FedInvent™ Patents

Patent Details for Tuesday, September 14, 2021 

This page was updated on Tuesday, September 14, 2021 at 10:06 PM GMT

Department of Health and Human Services (HHS) 

US 11116405 Partanen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
U.S. Public Health Service (USPHS)
APPLICANT(S) Profound Medical Inc. (Mississauga, Canada);  THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF HEALTH and HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH, OFFICE OF TECHNOLOGY TRANSFER (Bethesda, Maryland)
ASSIGNEE(S)
INVENTOR(S) Ari Ilkka Mikael Partanen (Bethesda, Maryland);  Matthew Robert Dreher (Rockville, Maryland);  Pavel Sergeyevich Yarmolenko (Germantown, Maryland);  Bradford Johns Wood (Bethesda, Maryland);  Elma Natalia Carvajal Gallardo (Enschede, Netherlands)
ABSTRACT The invention provides for a medical instrument (200) comprising a magnetic resonance imaging system (202) and a high-intensity focused ultrasound system (204) with an electronically controllable and a mechanically controllable focus. Execution of instructions by a processor (244) controlling the instrument cause the processor to: receive (100) a target zone (240, 264) descriptive of a zone within the subject; divide (102) the target zone into multiple sub-zones (416, 418, 420, 422, 424, 426, 428, 430, 432, 434); determine (104) a sequence (272) for moving the transducer position to each of the multiple sub-zones; determine (106) a selected sub-zone selected from the multiple sub-zones using the sequence; repeatedly control (108) the mechanical positioning system to move the transducer to the transducer position of the selected sub-zone; repeatedly acquire (110) the magnetic resonance thermometry data; repeatedly determine (112) a temperature property map (274); repeatedly heat (114) the regions independently to the target temperature by controlling the electronically controlled focus with a temperature feedback algorithm (286); and repeatedly change (116) the selected sub-zone using the sequence.
FILED Tuesday, April 09, 2013
APPL NO 14/390181
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/015 (20130101)
A61B 5/0036 (20180801) Original (OR) Class
A61B 5/055 (20130101)
A61B 5/7253 (20130101)
A61B 5/7264 (20130101)
A61B 34/10 (20160201)
A61B 2017/00084 (20130101)
A61B 2018/00791 (20130101)
A61B 2090/374 (20160201)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 7/02 (20130101)
A61N 2007/0091 (20130101)
A61N 2007/0095 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116445 Bentz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Brian Zahler Bentz (West Lafayette, Indiana);  Kevin John Webb (West Lafayette, Indiana);  Timothy Cheng-Hsien Wu (San Mateo, California);  Vaibhav Gaind (Fremont, California)
ABSTRACT Methods for locating blood vessels, lesions, and other discontinuities in tissue such as, but not limited to, the greater palatine artery (GPA) in the hard palate using an optical imaging process, surgical procedures utilizing the identified locations of discontinuities, and devices suitable for use during surgical procedures. According to one aspect, such a method locates a blood vessel or lesion in tissue by imaging the tissue via a diffuse optical imaging (DOI) process that measures light that travels through the tissue, and then locates the blood vessel or lesion in the tissue based on a difference in absorption of the light between the tissue and the blood vessel or lesion.
FILED Wednesday, May 09, 2018
APPL NO 15/975211
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 1/043 (20130101)
A61B 5/0059 (20130101)
A61B 5/0077 (20130101)
A61B 5/489 (20130101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 7/0012 (20130101)
G06T 2207/30101 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116459 Dejongh et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) ProtonVDA LLC (Naperville, Illinois)
ASSIGNEE(S) ProtonVDA LLC (Naperville, Illinois)
INVENTOR(S) Don F. Dejongh (Batavia, Illinois);  Victor Rykalin (Batavia, Illinois)
ABSTRACT A medical imaging system includes a first tracking detector and a second tracking detector. The tracking detectors are spaced to allow for an object to be present between the first tracking detector and the second tracking detector. The system also includes a residual range detector adjacent the first tracking detector. The residual range detector includes: (1) a scintillator material having a first surface at least partially covered with an anti-reflection material and a second surface facing the first tracking detector and (2) at least one photon detector coupled to the scintillator material at a third surface of the scintillator material different than the first surface and opposite the second surface.
FILED Thursday, May 19, 2016
APPL NO 15/159591
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/582 (20130101)
A61B 6/4216 (20130101)
A61B 6/4258 (20130101) Original (OR) Class
A61B 6/5205 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 2005/1054 (20130101)
A61N 2005/1087 (20130101)

Measurement of Nuclear or X-radiation
G01T 1/29 (20130101)
G01T 1/1603 (20130101)
G01T 5/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116729 Dahlman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Dental and Craniofacial Research (NIDCR)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) James Dahlman (Atlanta, Georgia);  Kalina Paunovska (Atlanta, Georgia)
ABSTRACT Lipid nanoparticles and compositions thereof are disclosed herein. An exemplary nanoparticle composition includes an ionizable lipid, a phospholipid, a PEG-lipid, and a cholesterol modified with a hydroxyl group near the D-sterol ring. The disclosed nanoparticle compositions can target liver Kupffer cells and endothelial cells more preferentially than hepatocytes which should be beneficial in treating liver diseases in which dysfunctional Kupffer cells and endothelial cells are involved in disease pathogenesis.
FILED Wednesday, January 15, 2020
APPL NO 16/743452
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5123 (20130101) Original (OR) Class
A61K 9/5146 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116738 Wu
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) CHILDREN'S HOSPITAL LOS ANGELES (Los Angeles, California)
ASSIGNEE(S) CHILDREN'S HOSPITAL LOS ANGELES (Los Angeles, California)
INVENTOR(S) Lingtao Wu (Rancho Palos Verdes, California)
ABSTRACT The invention provides methods for treating neutropenia in a subject in need thereof comprising providing a composition comprising a retinoid agonist and administering an effective amount of the composition to the subject to treat neutropenia, thereby treating neutropenia to the subject in need thereof.
FILED Friday, June 07, 2013
APPL NO 14/405141
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/192 (20130101)
A61K 31/196 (20130101) Original (OR) Class
A61K 45/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116753 Johnson
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
APPLICANT(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
ASSIGNEE(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S) Bankole A. Johnson (Charlottesville, Virginia)
ABSTRACT Compositions and methods are provided that are useful for diagnosing, treating, and monitoring alcohol dependence and disorders, susceptibility to alcohol dependence disorders, as well as drug related dependence and disorders. The methods include treating patients with an antagonist of the serotonin receptor 5-HT3 for such disorders, wherein the patient's serotonin transporter gene SLC6A4 is known to have particular genotypes.
FILED Friday, October 02, 2020
APPL NO 17/061749
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/4178 (20130101) Original (OR) Class
A61K 31/7048 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101)
C12Q 1/6888 (20130101)
C12Q 2600/106 (20130101)
C12Q 2600/156 (20130101)
C12Q 2600/172 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 20/00 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116754 Shirasu-Hiza et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of General Medical Sciences (NIGMS)
NIH Office of the Director (NIHOD)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Michele Shirasu-Hiza (New York, New York);  Julie Canman (New York, New York)
ABSTRACT This invention relates to methods and compositions for increasing immunity against, and survival of, a bacterial infection by inhibiting Target of Rapamycin (TOR) complex 2 or TORC 2. In particular, the current invention is useful in increasing immunity and survival after infection by Burkholderia cepacia as well as other bacteria since the agents that target TORC2 increase host tolerance of infection rather than target the clearance or containment of specific types of bacteria. This invention also relates to methods and compositions for increasing immunity against, survival of, and host tolerance to a bacterial infection by inhibiting the circadian regulator, Period protein.
FILED Monday, November 14, 2016
APPL NO 15/774403
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/436 (20130101) Original (OR) Class
A61K 31/519 (20130101)
A61K 31/715 (20130101)
A61K 31/4745 (20130101)
A61K 31/7105 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116757 Min et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Memorial Sloan Kettering Cancer Center (New York, New York);  St. Jude Children's Research Hospital (Memphis, Tennessee)
ASSIGNEE(S) MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York);  ST. JUDE CHILDREN'S RESEARCH HOSPITAL (Memphis, Tennessee)
INVENTOR(S) Jaeki Min (Memphis, Tennessee);  Daniel C. Scott (Marion, Arkansas);  Deepak Bhasin (Cordova, Tennessee);  Brenda A. Schulman (Memphis, Tennessee);  Bhuvanesh Singh (Old Westbury, New York);  Jared T. Hammill (Memphis, Tennessee);  R. Kiplin Guy (Memphis, Tennessee)
ABSTRACT In one aspect, the invention relates to substituted 1-phenyl-3-(piperidin-4-yl)urea analogs, derivatives thereof, and related compounds, which are useful as inhibitors of the DCN1-UBC12 interaction inhibitors of DCN1-mediated cullin-RING ligase activity, methods of making same, pharmaceutical compositions comprising same, methods of treating disorders using the disclosed compounds and compositions, methods of treating disorders associated with a DCN1-UBC12 interaction dysfunction, methods of treating disorders associated with a DCN1-mediated cullin-RING ligase activity dysfunction, methods of male contraception comprising the disclosed compounds and compositions, and kits comprising the disclosed compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
FILED Wednesday, November 13, 2019
APPL NO 16/683076
ART UNIT 1699 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/17 (20130101)
A61K 31/437 (20130101)
A61K 31/451 (20130101)
A61K 31/454 (20130101)
A61K 31/506 (20130101)
A61K 31/4525 (20130101)
A61K 31/4545 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 15/16 (20180101)
A61P 31/04 (20180101)
A61P 31/12 (20180101)

Heterocyclic Compounds
C07D 211/58 (20130101)
C07D 401/04 (20130101)
C07D 401/06 (20130101)
C07D 401/12 (20130101)
C07D 405/06 (20130101)
C07D 405/12 (20130101)
C07D 409/14 (20130101)
C07D 417/04 (20130101)
C07D 417/06 (20130101)
C07D 471/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116765 Gonda et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) GRIFOLS, S.A. (Los Angeles, California)
ASSIGNEE(S) GRIFOLS, S.A. (Los Angeles, California)
INVENTOR(S) Igor Gonda (San Francisco, California);  James Blanchard (El Granada, California);  David C. Cipolla (San Ramon, California);  Luiz Eduardo Moreira Bermudez (Corvallis, Oregon)
ABSTRACT Methods of treatment of NTM lung infections using formulations of liposomal ciprofloxacin. Specific liposome formulations and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described.
FILED Friday, June 26, 2020
APPL NO 16/914122
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/12 (20130101)
A61K 9/0073 (20130101)
A61K 9/0078 (20130101)
A61K 9/127 (20130101)
A61K 31/496 (20130101) Original (OR) Class
A61K 45/06 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116784 Parikh
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts)
INVENTOR(S) Samir M. Parikh (Boston, Massachusetts)
ABSTRACT Methods of treating ischemic tissue injury or kidney disease, e.g., delayed graft function, that include administering a Nicotinamide adenine dinucleotide (NAD)/niacinamide (NAM) pathway agonist.
FILED Tuesday, February 21, 2017
APPL NO 16/079963
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/44 (20130101)
A61K 31/403 (20130101)
A61K 31/455 (20130101)
A61K 31/706 (20130101)
A61K 31/711 (20130101)
A61K 31/4409 (20130101)
A61K 31/7084 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/10 (20180101)
A61P 13/12 (20180101)
A61P 41/00 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)
C12N 2310/11 (20130101)
C12N 2310/14 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5038 (20130101)
G01N 2800/50 (20130101)
G01N 2800/52 (20130101)
G01N 2800/347 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116804 Strandwitz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Holobiome, Inc. (South Boston, Massachusetts)
ASSIGNEE(S) Holobiome, Inc. (South Boston, Massachusetts)
INVENTOR(S) Philip Strandwitz (Medford, Massachusetts);  Kim Lewis (Newton, Massachusetts)
ABSTRACT The present disclosure relates to methods of treating at least one symptom of a mental disorder or disease of the central nervous system in a subject by modulating the amount of GABA produced in the subject's gut. The present disclosure also relates to methods of culturing the bacterial strain new bacterial strains. Also disclosed are methods of identifying bacterial strains capable of producing GABA, and engineering strains to produce GABA.
FILED Monday, March 13, 2017
APPL NO 16/084511
ART UNIT 1699 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/74 (20130101)
A61K 35/742 (20130101) Original (OR) Class
A61K 35/745 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/18 (20180101)
A61P 25/22 (20180101)
A61P 25/24 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/0008 (20130101)
C12N 9/0069 (20130101)
C12N 9/78 (20130101)
C12N 9/88 (20130101)
C12N 9/1096 (20130101)

Enzymes
C12Y 102/01019 (20130101)
C12Y 113/12001 (20130101)
C12Y 206/01082 (20130101)
C12Y 305/03011 (20130101)
C12Y 401/01015 (20130101)
C12Y 401/01017 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116815 Chen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of Mental Health (NIMH)
APPLICANT(S) The Penn State Research Foundation (University Park, Pennsylvania)
ASSIGNEE(S) The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S) Gong Chen (State College, Pennsylvania);  Gang-Yi Wu (State College, Pennsylvania);  Lei Zhang (State College, Pennsylvania);  Jiu-Chao Yin (State College, Pennsylvania);  Hana Yeh (State College, Pennsylvania);  Ning-Xin Ma (State College, Pennsylvania);  Grace Lee (State College, Pennsylvania)
ABSTRACT Provided are methods and compositions from reprogramming human glial cells into human neurons. The reprogramming is achieved using combinations of compounds that can modify signaling via Transforming growth factor beta (TGF-β), Bone morphogenetic protein (BMP), glycogen synthase kinase 3 (GSK-3), and γ-secretase/Notch pathways. The reprogramming is demonstrated using groups of three or four compounds that are chosen from the group thiazovivin, LDN193189, SB431542, TTNPB, CHIR99021, DAPT, VPA, SAG purmorphamine. Reprogramming is demonstrated using the group of LDN193189/CHIR99021/DAPT, the group of B431542/CHIR99021/DAPT, the group of LDN193189/DAPT/SB431542, the group of LDN193189/CHIR99021/SB431542, a three drug combination of SB431542/CHIR99021/DAPT. Reprogramming using functional analogs of the compounds is also provided, as are pharmaceutical formulations that contain the drug combinations.
FILED Monday, September 30, 2019
APPL NO 16/588054
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/00 (20130101)
A61K 31/506 (20130101)
A61K 31/506 (20130101)
A61K 31/519 (20130101)
A61K 31/519 (20130101)
A61K 31/4439 (20130101)
A61K 31/4439 (20130101)
A61K 38/05 (20130101) Original (OR) Class
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0619 (20130101)
C12N 2501/15 (20130101)
C12N 2501/155 (20130101)
C12N 2501/727 (20130101)
C12N 2501/998 (20130101)
C12N 2501/999 (20130101)
C12N 2506/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116816 Soliman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) Extend Biosciences, Inc. (Newton, Massachusetts)
ASSIGNEE(S) Extend Biosciences, Inc. (Newton, Massachusetts)
INVENTOR(S) Tarik Soliman (Cambridge, Massachusetts);  Laura M. Hales (Cambridge, Massachusetts);  Daniel B. Hall (Easton, Massachusetts);  Christopher So (Henderson, Nevada);  Howard P. Sard (Arlington, Massachusetts);  Vishnumurthy Hegde (Chelmsford, Massachusetts)
ABSTRACT The invention provides a parathyroid hormone (PTH) compound comprising a PTH peptide. The PTH compound has a significantly increased bioavailability or circulating half-life when compared to a bioavailability or a circulating half-life of a native form of the PTH peptide. The PTH compound has a significantly greater serum concentration at multiple timepoints post-administration to a rat when compared to that of a native PTH peptide.
FILED Tuesday, January 29, 2019
APPL NO 16/261507
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 38/10 (20130101) Original (OR) Class
A61K 38/22 (20130101)
A61K 47/60 (20170801)
A61K 47/551 (20170801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116818 Choe et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Children's Medical Center Corporation (Boston, Massachusetts);  Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Children's Medical Center Corporation Dana-Farber Cancer Institute (Boston, Massachusetts)
INVENTOR(S) Hyeryun Choe (Juno Beach, Florida);  Stephanie Jemielity (Waban, Massachusetts);  Dale T. Umetsu (Newton, Massachusetts);  Rosemarie H. De Kruyff (Newton, Massachusetts);  Gordon J. Freeman (Brookline, Massachusetts)
ABSTRACT The invention provides methods, compositions, and kits featuring agents that inhibit viral entry mediated by T-cell Immunoglobulin and Mucin-domain containing proteins (TIM proteins) and other phosphatidylserine receptors.
FILED Thursday, December 12, 2013
APPL NO 14/651934
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/685 (20130101)
A61K 31/713 (20130101)
A61K 31/7105 (20130101)
A61K 38/1774 (20130101) Original (OR) Class
A61K 45/00 (20130101)

Peptides
C07K 14/70503 (20130101)
C07K 16/2803 (20130101)
C07K 2317/76 (20130101)
C07K 2319/30 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)
C12N 15/1138 (20130101)
C12N 2310/11 (20130101)
C12N 2310/14 (20130101)
C12N 2310/17 (20130101)
C12N 2310/531 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116819 Scadden et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts);  The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts);  The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) David T. Scadden (Weston, Massachusetts);  Borja Saez (Boston, Massachusetts);  Francesca Ferraro (Lansdale, Pennsylvania);  Jonathan Hoggatt (Cambridge, Massachusetts)
ABSTRACT The present invention relates to methods and compositions for mobilizing hematopoietic stem cells and/or progenitor cells, and related methods of conditioning for engraftment of transplanted hematopoietic stem cells and/or progenitor cells, and methods of treating diseases requiring hematopoietic stem cell and/or progenitor cell transplantation.
FILED Friday, February 28, 2014
APPL NO 14/771280
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/395 (20130101)
A61K 31/395 (20130101)
A61K 31/727 (20130101)
A61K 31/727 (20130101)
A61K 35/28 (20130101)
A61K 36/00 (20130101)
A61K 38/193 (20130101)
A61K 38/193 (20130101)
A61K 38/195 (20130101) Original (OR) Class
A61K 38/195 (20130101)
A61K 38/202 (20130101)
A61K 38/202 (20130101)
A61K 38/1703 (20130101)
A61K 38/1703 (20130101)
A61K 39/3955 (20130101)
A61K 45/06 (20130101)
A61K 2035/124 (20130101)
A61K 2039/505 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0662 (20130101)
C12N 15/115 (20130101)
C12N 15/1136 (20130101)
C12N 2310/11 (20130101)
C12N 2310/16 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5073 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116827 Jones et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Materiel Development Activity (USAMMDA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) ETUBICS CORPORATION (Seattle, Washington)
ASSIGNEE(S) Etubics Corporation (Seattle, Washington)
INVENTOR(S) Frank R. Jones (Seattle, Washington);  Joseph Balint (Seattle, Washington);  Elizabeth Gabitzsch (Seattle, Washington)
ABSTRACT In certain embodiments, methods and compositions are provided for generating immune responses against tumor antigens such as antigens or epitopes of HER1, HER2/neu, HER3, HER4, or any combination thereof. In particular embodiments, there may be provided methods for constructing and producing recombinant adenovirus-based vector vaccines containing nucleic acid sequences encoding tumor antigens such as antigens or epitopes of HER1, HER2/neu, HER3, HER4, or any combination thereof, that allow for vaccinations in individuals with preexisting immunity to adenovirus.
FILED Saturday, June 02, 2018
APPL NO 16/615925
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/00117 (20180801)
A61K 39/001106 (20180801) Original (OR) Class
A61K 39/001152 (20180801)
A61K 2039/523 (20130101)

Peptides
C07K 16/2827 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
C12N 2710/10343 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116830 Price et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Silver Spring, Maryland)
ASSIGNEE(S) THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Gregory A. Price (Silver Spring, Maryland);  Che-Hung Robert Lee (Silver Spring, Maryland);  Margaret C. Bash (Silver Spring, Maryland)
ABSTRACT Immunogenic compositions that include a bacterial capsular polysaccharide conjugated to a carrier protein are described. In some embodiments, the bacterial capsular polysaccharide is a Neisseria meningitidis capsular polysaccharide. The carrier protein includes an N. meningitidis factor H binding protein (fHbp) linked to cholera toxin subunit B (CTB). Administration of the immunogenic compositions elicits an immune response that includes production of meningococcal polysaccharide-specific and fHbp-specific antibodies. Use of the immunogenic compositions as meningococcal vaccines is also described.
FILED Tuesday, December 18, 2018
APPL NO 16/954161
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/095 (20130101) Original (OR) Class
A61K 39/107 (20130101)
A61K 2039/70 (20130101)
A61K 2039/6037 (20130101)
A61K 2039/6068 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116846 Goldenberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Immunomedics, Inc. (Morris Plains, New Jersey)
ASSIGNEE(S) Immunomedics, Inc. (Morris Plains, New Jersey)
INVENTOR(S) David M. Goldenberg (Delray Beach, Florida);  Serengulam V. Govindan (Springfield, New Jersey)
ABSTRACT The present invention relates to therapeutic immunoconjugates comprising SN-38 attached to an antibody or antigen-binding antibody fragment. The antibody may bind to Trop-2 or CEACAM5 and the immunoconjugate may be administered at a dosage of between 4 mg/kg and 16 mg/kg, preferably 4, 6, 8, 9, 10, 12, or 16 mg/kg. When administered at specified dosages and schedules, the immunoconjugate can reduce solid tumors in size, reduce or eliminate metastases and is effective to treat cancers resistant to standard therapies, such as radiation therapy, chemotherapy or immunotherapy. Surprisingly, the immunoconjugate is effective to treat cancers that are refractory to or relapsed from irinotecan.
FILED Wednesday, October 21, 2020
APPL NO 17/076477
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/337 (20130101)
A61K 31/454 (20130101)
A61K 31/513 (20130101)
A61K 31/675 (20130101)
A61K 31/713 (20130101)
A61K 31/4184 (20130101)
A61K 31/4375 (20130101)
A61K 31/4745 (20130101)
A61K 31/7068 (20130101)
A61K 31/7088 (20130101)
A61K 39/39558 (20130101)
A61K 39/39558 (20130101)
A61K 41/0038 (20130101)
A61K 45/06 (20130101)
A61K 47/6803 (20170801)
A61K 47/6851 (20170801) Original (OR) Class
A61K 47/6855 (20170801)
A61K 47/6859 (20170801)
A61K 47/6863 (20170801)
A61K 47/6889 (20170801)
A61K 51/1045 (20130101)
A61K 2039/505 (20130101)
A61K 2300/00 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/1001 (20130101)
A61N 2005/1021 (20130101)

Peptides
C07K 16/30 (20130101)
C07K 16/2803 (20130101)
C07K 16/2833 (20130101)
C07K 16/2887 (20130101)
C07K 16/3007 (20130101)
C07K 16/3076 (20130101)
C07K 2317/24 (20130101)
C07K 2317/33 (20130101)
C07K 2317/77 (20130101)
C07K 2317/92 (20130101)
C07K 2317/94 (20130101)
C07K 2317/732 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116850 Hirsch et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S) Matthew Louis Hirsch (Chapel Hill, North Carolina);  Richard Jude Samulski (Chapel Hill, North Carolina)
ABSTRACT This invention relates to viral vectors for delivery of alpha-L-iduronidase to the cornea of a subject and methods of using the same for treatment and prevention of corneal clouding and blindness in a subject due to mucopolysaccharidosis I.
FILED Wednesday, February 22, 2017
APPL NO 16/076654
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/0048 (20130101)
A61K 35/76 (20130101)
A61K 48/00 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 27/00 (20180101)

Peptides
C07K 14/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/2402 (20130101)
C12N 9/2411 (20130101)
C12N 15/86 (20130101)
C12N 2710/10044 (20130101)
C12N 2750/14141 (20130101)
C12N 2750/14143 (20130101)
C12N 2800/22 (20130101)

Enzymes
C12Y 302/01076 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116851 Leonard et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Jack L. Leonard (Shrewsbury, Massachusetts);  Karl J. Simin (Princeton, Massachusetts);  Deborah M. Leonard (Shrewsbury, Massachusetts)
ABSTRACT The invention relates to the discovery of a vital new component of the Wnt pathway that regulates trafficking of β-catenin to the cell nucleus and novel therapeutic approaches to cancer treatment. Disclosed herein is a previously unknown, essential component of the Wnt/β-catenin signaling pathway that governs the quantity of β-catenin delivered to the cell nucleus. This intracellular inhibitor of β-catenin signaling (IBS) is transcribed from a second transcriptional start site adjacent to exon 3 of the Dkk3 gene and is required for early mouse development. IBS captures β-catenin destined for the nucleus in a complex with β-TrCP that is bound to the actin cytoskeleton and unavailable for nuclear translocation.
FILED Tuesday, October 18, 2016
APPL NO 15/765431
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0275 (20130101)
A01K 2217/072 (20130101)
A01K 2227/105 (20130101)
A01K 2267/0331 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 31/337 (20130101)
A61K 31/351 (20130101)
A61K 33/243 (20190101)
A61K 48/005 (20130101) Original (OR) Class
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/4703 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116854 Tanifum et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of Child Health and Human Development (NICHD)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) Texas Children's Hospital (Houston, Texas)
ASSIGNEE(S) Texas Children's Hospital (Houston, Texas)
INVENTOR(S) Eric A. Tanifum (Richmond, Texas);  Ketankumar B. Ghaghada (Sugar Land, Texas);  Ananth V. Annapragada (Manvel, Texas)
ABSTRACT A liposomal composition (“ADx-001”) is provided, ADx-001 comprising a first phospholipid; a sterically bulky excipient that is capable of stabilizing the liposomal composition; a second phospholipid that is derivatized with a first polymer; a macrocyclic gadolinium-based imaging agent; and a third phospholipid that is derivatized with a second polymer, the second polymer being conjugated to a targeting ligand. The macrocyclic gadolinium-based imaging agent may be conjugated to a fourth phospholipid.
FILED Friday, January 29, 2021
APPL NO 17/162126
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/24 (20130101)
A61K 49/108 (20130101)
A61K 49/1812 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116862 Xie
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of Child Health and Human Development (NICHD)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts)
ASSIGNEE(S) THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts)
INVENTOR(S) Zhongcong Xie (Andover, Massachusetts)
ABSTRACT A device for selectively providing an odor-rich environment includes a housing and a cover. The housing includes a central cavity and a plurality of chambers configured to store a predefined fragrance therein and having a respective outlet formed on an outer wall of the housing. The cover includes an exterior surface having at least one vent formed on the exterior surface. The exterior surface includes an interior sidewall and an exterior sidewall forming an inner chamber that slidably engages the housing such that the cover is configured to move between an open position and a closed position. Responsive to the cover being in the open position, the at least one vent is generally adjacent to the outlet of at least one of the plurality of chambers of the housing. The odor-rich environment can assist in preventing and/or treating postoperative delirium (POD) postoperative cognitive dysfunction (POCD), and/or pain in a subject.
FILED Wednesday, March 08, 2017
APPL NO 16/082853
ART UNIT 1796 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 9/122 (20130101)
A61L 9/125 (20130101) Original (OR) Class
A61L 2209/11 (20130101)
A61L 2209/12 (20130101)
A61L 2209/13 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116875 Alsberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) Eben Alsberg (Cleveland, Ohio);  Oju Jeon (Cleveland, Ohio);  Tae-Hee Kim (Cleveland, Ohio)
ABSTRACT A composition includes a dual crosslinkable hydrogel that includes a plurality of polymer macromers, which are crosslinked with a first agent and a second agent different than the first agent, wherein the crosslinks formed using the second agent are reversible and repeatable to allow the mechanical properties of the hydrogel to be dynamically adjusted.
FILED Tuesday, August 21, 2018
APPL NO 16/107774
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/20 (20130101)
A61L 27/26 (20130101)
A61L 27/26 (20130101)
A61L 27/26 (20130101)
A61L 27/44 (20130101) Original (OR) Class
A61L 27/52 (20130101)
A61L 27/54 (20130101)
A61L 27/58 (20130101)
A61L 27/3608 (20130101)
A61L 27/3834 (20130101)
A61L 2300/236 (20130101)
A61L 2300/252 (20130101)
A61L 2300/412 (20130101)
A61L 2300/414 (20130101)
A61L 2400/16 (20130101)
A61L 2430/40 (20130101)

Polysaccharides; Derivatives Thereof
C08B 37/0084 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 65/002 (20130101)

Derivatives of Natural Macromolecular Compounds
C08H 1/06 (20130101)

Compositions of Macromolecular Compounds
C08L 5/04 (20130101)
C08L 5/04 (20130101)
C08L 5/04 (20130101)
C08L 5/08 (20130101)
C08L 89/06 (20130101)
C08L 89/06 (20130101)
C08L 89/06 (20130101)
C08L 89/06 (20130101)
C08L 2205/04 (20130101)
C08L 2312/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116976 Edgerton et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
United States Army (USA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) The Regents of the University of California (Oakland, California);  California Institute of Technology (Pasadena, California);  University of Louisville Research Foundation, Inc. (Louisville, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Victor Reggie Edgerton (Los Angeles, California);  Roland R. Roy (Playa Vista, California);  Yury Gerasimenko (Los Angeles, California);  Joel W. Burdick (Pasadena, California);  Susan J. Harkema (Louisville, California);  Jonathan Hodes (Louisville, Kentucky);  Yu-Chong Tai (Pasadena, California);  Mandheerej S. Nandra (Pasadena, California);  Claudia A. Angeli (Louisville, Kentucky);  Thomas Anthony Desautels (Pasadena, California)
ABSTRACT Methods comprising applying electrical stimulation to patients in conjunction with physical training are described.
FILED Tuesday, January 23, 2018
APPL NO 15/878325
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body
A61H 1/0237 (20130101)
A61H 1/0274 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0551 (20130101)
A61N 1/0553 (20130101)
A61N 1/0556 (20130101)
A61N 1/3616 (20130101)
A61N 1/36003 (20130101)
A61N 1/36103 (20130101) Original (OR) Class

Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment
A63B 21/00181 (20130101)
A63B 22/0235 (20130101)
A63B 69/0064 (20130101)
A63B 2213/004 (20130101)
A63B 2220/805 (20130101)
A63B 2230/60 (20130101)

Rotary-piston, or Oscillating-piston, Positive-displacement Machines for Liquids; Rotary-piston, or Oscillating-piston, Positive-displacement Pumps
F04C 2270/0421 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117123 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Trustees of Boston College (Chestnut Hill, Massachusetts)
ASSIGNEE(S) The Trustees of Boston College (Chestnut Hill, Massachusetts)
INVENTOR(S) Xiao-Xiang Zhang (Newton, Massachusetts);  Yang Hu (Hockesssin, Delaware)
ABSTRACT In one aspect, the disclosure relates to a mode of asymmetric induction in radical processes based on enhanced hydrogen-bonding capability and the situation of metal centers in cavity-like chiral environments. Also disclosed is an asymmetric system for stereoselective synthesis of cyclopropane and aziridine derivatives. The disclosed Co(II)-based metalloradical system has been shown to have an unusual capability of controlling both the degree and sense of asymmetric induction in cyclopropanation and aziridination reactions in a systematic manner. The disclosed system is applicable to a broad scope of substrates having diazo or azido moieties and exhibits a remarkable profile of reactivity and selectivity, providing access to cyclopropane diastereomers and aziridine enantiomers in highly enantioenriched forms. Also disclosed are catalysts useful in the disclosed processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
FILED Thursday, April 16, 2020
APPL NO 16/851041
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 31/183 (20130101) Original (OR) Class

Acyclic or Carbocyclic Compounds
C07C 67/347 (20130101)
C07C 2601/02 (20170501)

Heterocyclic Compounds
C07D 203/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117808 Handa et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) University of Georgia Research Foundation, Inc. (Athens, Georgia)
ASSIGNEE(S) University of Georgia Research Foundation, Inc. (Athens, Georgia)
INVENTOR(S) Hitesh Handa (Athens, Georgia);  Marcus Goudie (Athens, Georgia);  Jitendra Pant (Athens, Georgia);  Bryan Grommersch (Alpharetta, Georgia);  Sean Hopkins (Athens, Georgia)
ABSTRACT Nitric oxide-releasing materials, methods of making nitric oxide-releasing materials, and uses of nitric oxide-releasing materials are provided. The nitric oxide-releasing materials include a mesoporous silica core and an outer surface having a plurality of nitric oxide donors. In an exemplary aspects, the nitric oxide-releasing material includes a mesoporous diatomaceous earth core, and an outer surface having a plurality of S-nitroso-N-acetyl-penicillamine groups covalently attached thereto. Uses of the nitric oxide-releasing materials can include coatings for medical devices such as catheters, grafts, and stents; wound gauzes; acne medications; and antiseptic mouthwashes; among others.
FILED Wednesday, August 01, 2018
APPL NO 16/051812
ART UNIT 1788 — Miscellaneous Articles, Stock Material
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/28 (20130101)
A61L 27/54 (20130101)
A61L 27/56 (20130101)
A61L 27/306 (20130101)
A61L 27/3637 (20130101)
A61L 29/08 (20130101)
A61L 29/16 (20130101)
A61L 29/106 (20130101)
A61L 29/146 (20130101)
A61L 31/08 (20130101)
A61L 31/16 (20130101)
A61L 31/088 (20130101)
A61L 31/146 (20130101)
A61L 2300/114 (20130101)
A61L 2420/04 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 33/149 (20130101) Original (OR) Class

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/82 (20130101)
C01P 2004/03 (20130101)
C01P 2004/61 (20130101)
C01P 2006/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117856 Fleeman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida)
ASSIGNEE(S) UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida)
INVENTOR(S) Renee Fleeman (Tampa, Florida);  Radleigh G. Santos (Port St. Lucie, Florida);  Marcello Angelo Giulianotti (Port St. Lucie, Florida);  Lindsey Shaw (Tampa, Florida)
ABSTRACT Disclosed herein are efflux pump inhibitors and pharmaceutical compositions comprising the same. The efflux pump inhibitors may be used in methods of preventing antibiotic resistance in a subject, and in methods of treating a bacterial infection in a subject. The efflux pump inhibitor may be co-administered with an antibiotic.
FILED Monday, April 29, 2019
APPL NO 16/397946
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/137 (20130101)
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/00 (20180101)
A61P 31/04 (20180101)

Acyclic or Carbocyclic Compounds
C07C 211/27 (20130101) Original (OR) Class

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117858 Schoenberger et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Center for Research Resources (NCRR)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute on Aging (NIA)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Matthias Schoenberger (Charlestown, Massachusetts);  Jacob Hooker (Charlestown, Massachusetts)
ABSTRACT Provided herein are radiolabeled compounds useful for minimally invasive imaging techniques. An exemplary radiolabeled compound provided herein is useful as a radiotracer for position emission tomography imaging of voltage gated sodium channels. Methods for prepared unlabeled and labeled compounds, and diagnostic methods using the compounds are also provided.
FILED Thursday, January 11, 2018
APPL NO 16/477257
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 51/04 (20130101)

General Methods of Organic Chemistry; Apparatus Therefor
C07B 2200/05 (20130101)

Acyclic or Carbocyclic Compounds
C07C 231/12 (20130101) Original (OR) Class
C07C 237/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117882 Acker et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Emory University (Atlanta, Georgia)
ASSIGNEE(S) Emory University (Atlanta, Georgia)
INVENTOR(S) Timothy M. Acker (San Francisco, California);  Dennis C. Liotta (Atlanta, Georgia);  Stephen F. Traynelis (Decatur, Georgia);  Yao Jing (Dunwoody, Georgia)
ABSTRACT This disclosure relates to pyrazoline dihydroquinolone derivatives, pharmaceutical compositions, and uses. In certain embodiments, the compounds are selective NMDA receptor inhibitors and are useful in therapeutic methods related thereto. In certain embodiments, this disclosure relates to pharmaceutical compositions comprising a compound of the following formula: or salts, esters, or prodrugs thereof, as provided herein.
FILED Thursday, August 02, 2018
APPL NO 16/053265
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/497 (20130101)
A61K 31/4709 (20130101)
A61K 31/4709 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)

Heterocyclic Compounds
C07D 401/04 (20130101)
C07D 401/14 (20130101) Original (OR) Class

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117884 Wagner et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts);  The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Steven L. Wagner (San Diego, California);  William C. Mobley (La Jolla, California);  Rudolph E. Tanzi (Hull, Massachusetts);  Graham Johnson (Sanbornton, New Hampshire);  Ronald Buckle (Delmar, New York);  Nicholas Mayhew (Niskayuna, New York);  Robert Jason Herr (Voorheesville, New York);  Kevin D. Rynearson (La Mesa, California)
ABSTRACT Provided herein are compounds and methods for treating a disorder associated with aberrant Aβ peptide levels, including Alzheimer's disease.
FILED Friday, October 25, 2019
APPL NO 16/664621
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/28 (20180101)

Heterocyclic Compounds
C07D 401/14 (20130101) Original (OR) Class
C07D 413/14 (20130101)
C07D 487/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117914 Pemberton et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
ASSIGNEE(S) Arizona Board of Regents on behalf of the University of Arizona (Tucson, Arizona)
INVENTOR(S) Jeanne E. Pemberton (Tucson, Arizona);  Robin L. Polt (Tucson, Arizona);  Raina M. Maier (Tucson, Arizona);  Ricardo Palos Pacheco (Tucson, Arizona)
ABSTRACT The present invention provides carbohydrate-based surfactants and methods for producing the same. Methods for producing carbohydrate-based surfactants include using a glycosylation promoter to link a carbohydrate or its derivative to a hydrophobic compound.
FILED Tuesday, November 22, 2016
APPL NO 15/358159
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 3/003 (20130101)
C07F 9/94 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 1/00 (20130101)
C07H 15/04 (20130101)
C07H 15/06 (20130101)
C07H 15/14 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117922 Leal et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Nicole A Leal (Gainesville, Florida);  Steven A Benner (Gainesville, Florida)
ASSIGNEE(S)
INVENTOR(S) Nicole A Leal (Gainesville, Florida);  Steven A Benner (Gainesville, Florida)
ABSTRACT This invention claims processes that append a single nucleotide having a 3′-ONH2 moiety to the 3′-ends of an oligonucleotide primer using 3′-deoxynucleoside triphosphates that have, instead of a 3′-OH moiety, a 3′-ONH2 moiety, where the nucleotides contain both standard and non-standard nucleobases, and where as a key claim limitation, substantially no hydroxylamine is present in the solutions used in the claimed processes.
FILED Monday, November 11, 2019
APPL NO 16/679501
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 19/10 (20130101)
C07H 19/12 (20130101)
C07H 19/14 (20130101)
C07H 19/20 (20130101) Original (OR) Class
C07H 19/048 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117933 Deverman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
NIH Office of the Director (NIHOD)
National Institute of Mental Health (NIMH)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Benjamin E. Deverman (Pasadena, California);  Paul H. Patterson (Altadena, California);  Viviana Gradinaru (La Cañada Flintridge, California)
ABSTRACT Provided herein are methods of selective screening. In addition, various targeting proteins and sequences, as well as methods of their use, are also provided.
FILED Monday, November 11, 2019
APPL NO 16/680402
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/47 (20130101)
A61K 38/50 (20130101)
A61K 38/1709 (20130101)
A61K 38/2093 (20130101)
A61K 38/4813 (20130101)
A61K 39/3955 (20130101)
A61K 48/005 (20130101)
A61K 48/0058 (20130101)

Peptides
C07K 7/06 (20130101)
C07K 14/005 (20130101) Original (OR) Class
C07K 2319/33 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101)
C12N 15/1068 (20130101)
C12N 2750/14122 (20130101)
C12N 2750/14143 (20130101)
C12N 2750/14145 (20130101)
C12N 2810/6027 (20130101)

Enzymes
C12Y 304/14009 (20130101)
C12Y 305/01015 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117934 McFadden et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona);  Oncomyx Therapeutics, Inc. (Phoenix, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona);  ONCOMYX THERAPEUTICS, INC. (Phoenix, Arizona)
INVENTOR(S) Douglas Grant McFadden (Tempe, Arizona);  Mohammed Masmudur Rahman (Chandler, Arizona);  Nancy Villa (Tempe, Arizona);  Lino Torres-Dominguez (Tempe, Arizona);  Lina Franco Achury (Tempe, Arizona);  Leslie Lynne Sharp (Rancho Santa Fe, California)
ABSTRACT Disclosed herein, in certain embodiments, are recombinant myxoma viruses (MYXVs) and nucleic acid constructs encoding the recombinant MYXVs. In some embodiments, the MYXVs are engineered to inactivate or attenuate an activity or expression level of an M153 protein. In some embodiments, the MYXVs are engineered to express one or more transgenes such as a tumor necrosis factor (TNF), interleukin-12 (IL-12), or decorin. Also disclosed herein, in certain embodiments, are methods of using the MYXVs. Some embodiments include providing a MYXV as described herein to a subject in need thereof.
FILED Wednesday, September 02, 2020
APPL NO 17/010711
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/275 (20130101)
A61K 45/06 (20130101)
A61K 2039/545 (20130101)
A61K 2039/572 (20130101)
A61K 2039/585 (20130101)
A61K 2039/5154 (20130101)
A61K 2039/5256 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/04 (20180101)

Peptides
C07K 14/005 (20130101) Original (OR) Class
C07K 14/525 (20130101)
C07K 14/5434 (20130101)
C07K 2319/33 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2710/24022 (20130101)
C12N 2710/24033 (20130101)
C12N 2710/24071 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117935 Dong et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Min Dong (Weatogue, Connecticut);  Liang Tao (Boston, Massachusetts)
ABSTRACT Disclosed herein are botulinum neurotoxin (BoNT) polypeptides with a modified BoNT/B4 receptor binding domain (B4-HC) having amino acid mutations that modify the binding of the BoNT to the human SytII receptor. Specific mutations and combinations of mutations are disclosed. Isolated modified HCs, polypeptides comprising such modified HCs, chimeric molecules, pharmaceutical compositions, and methods of making and using the same are also disclosed. Methods of identifying additional such modified receptor binding domains, are further disclosed.
FILED Thursday, August 24, 2017
APPL NO 16/326905
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 14/33 (20130101) Original (OR) Class
C07K 2319/55 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/52 (20130101)

Enzymes
C12Y 304/24069 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117936 Lohmueller
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburg Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Jason Lohmueller (Pittsburgh, Pennsylvania)
ABSTRACT A chimeric antigen receptor is disclosed that includes: (a) an extracellular high affinity streptavidin;(b) a hinge domain from CD8; (c) a CD28 transmembrane domain; (d) an intracellular 4-1BB and/or CD28 signaling domain; and (e) an intracellular CD3 zeta signaling domain, wherein (a)-(e) are in N-terminal to C-terminal order. Nucleic acids encoding this chimeric antigen receptor, and T and natural killer (NK) cells transformed with this chimeric antigen receptor are also disclosed. The use of this chimeric antigen receptor for the treatment of tumors is also disclosed.
FILED Wednesday, November 07, 2018
APPL NO 16/183579
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101)
A61K 38/00 (20130101)
A61K 39/0011 (20130101)
A61K 2039/5156 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
A61P 35/02 (20180101)

Peptides
C07K 14/36 (20130101) Original (OR) Class
C07K 14/7051 (20130101)
C07K 14/70517 (20130101)
C07K 14/70521 (20130101)
C07K 14/70578 (20130101)
C07K 16/2803 (20130101)
C07K 16/2863 (20130101)
C07K 16/2887 (20130101)
C07K 16/3092 (20130101)
C07K 2317/24 (20130101)
C07K 2317/73 (20130101)
C07K 2317/622 (20130101)
C07K 2319/02 (20130101)
C07K 2319/03 (20130101)
C07K 2319/20 (20130101)
C07K 2319/30 (20130101)
C07K 2319/33 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117943 Garcia et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Kenan Christopher Garcia (Menlo Park, California);  Aron Levin (New York City, New York);  Aaron Ring (Menlo Park, California)
ABSTRACT Novel human interleukin-2 (IL-2) muteins or variants thereof, and nucleic acid molecules and variants thereof are provided. Methods for producing these muteins as well as methods for stimulating the immune system of an animal are also disclosed. In addition, the invention provides recombinant expression vectors comprising the nucleic acid molecules of this invention and host cells into which expression vectors have been introduced. Pharmaceutical compositions are included comprising a therapeutically effective amount of a human IL-2 mutein of the invention and a pharmaceutically acceptable carrier. The IL-2 muteins can be used in pharmaceutical compositions for use in treatment of cancer and in stimulating the immune response.
FILED Thursday, December 13, 2018
APPL NO 16/219786
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 14/55 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117944 Manzano et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) UNIVERSITY OF WASHINGTON (Seattle, Washington);  THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California)
ASSIGNEE(S) University Of Washington (Seattle, Washington);  The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Daniel Adriano Silva Manzano (Seattle, Washington);  Shawn Yu (Seattle, Washington);  Umut Ulge (Seattle, Washington);  David Baker (Seattle, Washington);  Kenan Christopher Garcia (Stanford, California);  Jamie Spangler (Stanford, California);  Carl Walkey (Seattle, Washington);  Alfredo Quijano Rubio (Seattle, Washington);  Brian Weitzner (Seattle, Washington)
ABSTRACT De novo designed polypeptides that bind to IL-2 receptor βγc heterodimer (IL-2Rβγc), IL-4 receptor αγc heterodimer (IL-4Rαγc), or IL-13 receptor α subunit (IL-13Rα) are disclosed, as are methods for using and designing the polypeptides.
FILED Thursday, June 18, 2020
APPL NO 16/905669
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 47/60 (20170801)
A61K 47/62 (20170801)

General Methods of Organic Chemistry; Apparatus Therefor
C07B 2200/13 (20130101)

Peptides
C07K 14/55 (20130101) Original (OR) Class
C07K 14/5406 (20130101)
C07K 14/5437 (20130101)
C07K 14/5443 (20130101)
C07K 2319/30 (20130101)
C07K 2319/33 (20130101)
C07K 2319/74 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117952 Kapp et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Omniox, Inc. (San Carlos, California)
ASSIGNEE(S) OMNIOX, INC. (San Carlos, California)
INVENTOR(S) Gregory Kapp (San Francisco, California);  Laura Serwer (Brisbane, California);  Natacha Le Moan (San Francisco, California);  Stephen P. L. Cary (San Mateo, California)
ABSTRACT The invention provides polymeric H-NOX proteins for the delivery of oxygen with longer circulation half-lives compared to monomeric H-NOX proteins. Polymeric H-NOX proteins extravasate into and preferentially accumulate in tumor tissue for sustained delivery of oxygen. The invention also provides the use of H-NOX proteins as radiosensitizers for the treatment of brain cancers.
FILED Friday, July 17, 2020
APPL NO 16/931736
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/41 (20130101)
A61K 38/164 (20130101)
A61K 45/06 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/10 (20130101)
A61N 2005/1098 (20130101)

Peptides
C07K 14/795 (20130101) Original (OR) Class
C07K 2319/21 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/53 (20130101)
G01N 33/57407 (20130101)
G01N 2800/52 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117976 Braciale et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
ASSIGNEE(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S) Thomas J. Braciale (Charlottesville, Virginia);  Taeg S. Kim (Charlottesville, Virginia)
ABSTRACT The present application discloses a previously unknown function of CD24 expressed on a subset of dendritic cells. The invention encompasses regulating CD24 on these cells to regulate erythropoiesis, induce EPO production and levels, increase RBC levels, and to treat, for example, stress-mediated erythropoiesis. The compositions and methods of the invention are useful, for example, in treating anemia.
FILED Monday, September 24, 2018
APPL NO 16/139428
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 39/3955 (20130101)
A61K 45/06 (20130101)
A61K 2039/505 (20130101)

Peptides
C07K 16/2896 (20130101) Original (OR) Class
C07K 2317/75 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117977 Viapiano et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts)
ASSIGNEE(S) THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts)
INVENTOR(S) Mariano S. Viapiano (Syracuse, New York);  Nandhu Mohan Sobhana (Syracuse, New York);  Ennio Antonio Chiocca (Weston, Massachusetts)
ABSTRACT Embodiments described herein provide anti-fibulin-3 antibodies, recombinant proteins that bind specifically to fibulin-3, compositions and the treatment methods comprising these antibodies and recombinant proteins.
FILED Wednesday, January 30, 2019
APPL NO 16/262654
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/17 (20130101)
A61K 31/17 (20130101)
A61K 31/166 (20130101)
A61K 31/166 (20130101)
A61K 31/175 (20130101)
A61K 31/175 (20130101)
A61K 31/475 (20130101)
A61K 31/475 (20130101)
A61K 31/495 (20130101)
A61K 31/495 (20130101)
A61K 39/3955 (20130101)
A61K 39/3955 (20130101)
A61K 45/06 (20130101)
A61K 49/0021 (20130101)
A61K 2039/54 (20130101)
A61K 2039/505 (20130101)
A61K 2039/545 (20130101)
A61K 2039/5158 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Peptides
C07K 16/22 (20130101)
C07K 16/30 (20130101) Original (OR) Class
C07K 16/3053 (20130101)
C07K 2317/24 (20130101)
C07K 2317/34 (20130101)
C07K 2317/73 (20130101)
C07K 2317/76 (20130101)
C07K 2317/92 (20130101)
C07K 2317/622 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0636 (20130101)
C12N 5/0646 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118150 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
APPLICANT(S) Research Foundation of the City University of New York (New York, New York);  Memorial Sloan Kettering Cancer Center (New York, New York)
ASSIGNEE(S) Research Foundation of the City University of New York (New York, New York);  Memorial Sloan Kettering Cancer Center (New York, New York)
INVENTOR(S) Sihong Wang (Scarsdale, New York);  A. H. Rezwanuddin Ahmed (New York, New York);  Xuejun Jiang (Cresskill, New Jersey);  Chun-wei Chi (New York, New York);  Chenghai Li (New York, New York)
ABSTRACT A layered, microfluidic array is disclosed. The array has a first layer with a culture channels extending in a first longitudinal direction. Each culture channel includes multiple traps that entrap cell or tissue samples. The array also has a second layer with microfluidic channels extending in a second longitudinal direction that is orthogonal the first longitudinal direction. A third layer, disposed between the first layer and the second layer, has pores arranged within the third layer such that each nest is vertically stacked above, and fluidly connected with, a corresponding culture chamber in the first layer. Each nest is fluidly isolated from adjacent nests by a fluid impermeable region of the third layer such that horizontal diffusion of water within the third layer is prevented.
FILED Thursday, January 10, 2019
APPL NO 16/244797
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502715 (20130101)
B01L 3/502746 (20130101)
B01L 3/502761 (20130101)
B01L 2200/0668 (20130101)
B01L 2300/087 (20130101)
B01L 2300/168 (20130101)
B01L 2300/0816 (20130101)
B01L 2300/0819 (20130101)
B01L 2300/0874 (20130101)
B01L 2300/0887 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 23/16 (20130101) Original (OR) Class
C12M 23/22 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118162 Humes et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) SeaStar Medical, Inc. (Cardiff-By-The-Sea, California)
ASSIGNEE(S) SeaStar Medical, Inc. (Denver, Colorado)
INVENTOR(S) H. David Humes (Ann Arbor, Michigan);  Deborah A. Buffington (Ann Arbor, Michigan);  Christopher J. Pino (Saline, Michigan)
ABSTRACT The present invention relates to a cytopheretic cartridge for use in treating and/or preventing inflammatory conditions within a subject and to related methods. More particularly, the invention relates to a cytopheretic cartridge that includes a housing and, disposed within the housing, a solid support capable of sequestering activated leukocytes and/or platelets.
FILED Monday, July 31, 2017
APPL NO 15/664884
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 1/1698 (20130101)
A61M 1/3672 (20130101)
A61M 1/3675 (20130101)
A61M 1/3679 (20130101)
A61M 2202/0427 (20130101)
A61M 2202/0439 (20130101)

Separation
B01D 63/02 (20130101)
B01D 2313/44 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0634 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118164 Leen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Baylor College of Medicine (Houston, Texas)
ASSIGNEE(S) BAYLOR COLLEGE OF MEDICINE (Houston, Texas)
INVENTOR(S) Ann Marie Leen (Bellaire, Texas);  Juan Fernando Vera Valdes (Bellaire, Texas);  Cliona M. Rooney (Bellaire, Texas);  Ulrike Gerdemann (Cambridge, Massachusetts)
ABSTRACT The present invention concerns methods of generating CTLs that are able to target at least one antigen from two or more viruses. The method includes exposing mixtures of peptides for different antigens to the same plurality of PBMCs and, at least in certain aspects, expanding the cells in the presence of IL4 and IL7.
FILED Monday, February 26, 2018
APPL NO 15/905176
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 2039/57 (20130101)
A61K 2039/70 (20130101)
A61K 2039/572 (20130101)
A61K 2039/577 (20130101)
A61K 2039/5158 (20130101)
A61K 2039/55527 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0638 (20130101) Original (OR) Class
C12N 7/00 (20130101)
C12N 2501/2302 (20130101)
C12N 2501/2304 (20130101)
C12N 2501/2307 (20130101)
C12N 2501/2315 (20130101)
C12N 2710/16134 (20130101)
C12N 2710/16234 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118167 Stone et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Everett Stone (Austin, Texas);  Donjeta Gjuka (Austin, Texas)
ABSTRACT Methods and compositions related to the engineering of a protein with MTA/ADO-degrading enzyme activity are described. For example, in certain aspects there may be disclosed an MTase capable of degrading MTA/ADO. Furthermore, certain aspects of the invention provide compositions and methods for the treatment of cancer or SCID with an MTase using the disclosed proteins or nucleic acids.
FILED Tuesday, November 17, 2020
APPL NO 16/950622
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/45 (20130101)
A61K 39/3955 (20130101)
A61K 47/60 (20170801)
A61K 47/6849 (20170801)
A61K 47/6851 (20170801)
A61K 47/6855 (20170801)
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/02 (20180101)
A61P 35/04 (20180101)

Peptides
C07K 16/2818 (20130101)
C07K 2317/76 (20130101)
C07K 2317/622 (20130101)
C07K 2319/30 (20130101)
C07K 2319/33 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/96 (20130101)
C12N 9/1077 (20130101) Original (OR) Class

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101)
C12Q 2600/106 (20130101)
C12Q 2600/156 (20130101)

Enzymes
C12Y 204/02028 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/573 (20130101)
G01N 33/574 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118185 Lewin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida);  The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida);  The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Alfred S. Lewin (Gainesville, Florida);  William W. Hauswirth (Gainesville, Florida);  Michael T. Massengill (Gainesville, Florida);  William Beltran (Philadelphia, Pennsylvania);  Gustavo D. Aguirre (Media, Pennsylvania);  Artur Cideciyan (Lafayette Hill, Pennsylvania);  Samuel Jacobson (Penn Valley, Pennsylvania)
ABSTRACT Aspects of the disclosure relate to methods and compositions for treating retinitis pigmentosa. In some aspects, the disclosure provides compositions and methods for delivering an interfering nucleic acid (for example an interfering RNA) to a subject in order to reduce expression of one or both alleles of an endogenous rho gene (for example a mutant rho allele associated with retinitis pigmentosa) in the subject. In some embodiments, a replacement rho gene that is resistant to the interfering nucleic acid also is delivered to the subject.
FILED Wednesday, March 01, 2017
APPL NO 16/081307
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 27/02 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101)
C12N 15/113 (20130101)
C12N 15/1138 (20130101) Original (OR) Class
C12N 2310/14 (20130101)
C12N 2310/14 (20130101)
C12N 2310/122 (20130101)
C12N 2310/141 (20130101)
C12N 2310/531 (20130101)
C12N 2310/531 (20130101)
C12N 2330/51 (20130101)
C12N 2750/14143 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118186 Garcia-Blanco et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Mariano A. Garcia-Blanco (Galveston, Texas);  Gaddiel Galarza-Munoz (Galveston, Texas);  Shelton S. Bradrick (Galveston, Texas)
ABSTRACT The present invention includes compositions and methods for treating an autoimmune disorder or a cancer in a subject in need thereof, the method comprising: administering an effective amount of a composition comprising an oligonucleotide that specifically binds a complementary sequence of the Interleukin-7 receptor (IL7R) pre-mRNA that influences splicing of exon 6, wherein the SM-ASO increases or decreases inclusion of exon 6 in IL7R pre-mRNAs and respectively decreases or increases expression of the soluble isoform of IL7R (sIL7R). In certain embodiments, the oligonucleotide is an antisense oligonucleotide (ASO), or a splice-modulating antisense oligonucleotide (SM-ASO).
FILED Monday, September 21, 2020
APPL NO 17/027467
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7088 (20130101)
A61K 45/06 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1138 (20130101) Original (OR) Class
C12N 2310/11 (20130101)
C12N 2320/31 (20130101)
C12N 2320/33 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118206 Bau et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Haim H. Bau (Swarthmore, Pennsylvania);  Michael G. Mauk (Philadelphia, Pennsylvania);  Jinzhao Song (Philadelphia, Pennsylvania);  Changchun Liu (Bala Cynwyd, Pennsylvania)
ABSTRACT Disclosed herein are methods for multiple stage isothermal amplification of nucleic acid comprising a first substantially isothermal amplification reaction on the nucleic acid to generate a first amplification product and at least one substantially isothermal amplification reaction on the first amplification product to generate at least one second amplification product in an amount sufficient for recovery, testing, or characterization.
FILED Friday, January 13, 2017
APPL NO 16/068560
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/34 (20130101) Original (OR) Class

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/702 (20130101)
C12Q 1/703 (20130101)
C12Q 1/6846 (20130101)
C12Q 1/6846 (20130101)
C12Q 1/6848 (20130101)
C12Q 1/6893 (20130101)
C12Q 2521/107 (20130101)
C12Q 2521/507 (20130101)
C12Q 2527/101 (20130101)
C12Q 2537/143 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118210 Bourdeau et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Raymond W. Bourdeau (Watertown, Massachusetts);  Anupama Lakshmanan (Pasadena, California);  Arash Farhadi (Pasadena, California);  Mikhail G. Shapiro (Los Angeles, California);  Audrey Lee-Gosselin (Pasadena, California)
ABSTRACT Hybrid gas vesicle gene cluster (GVGC) configured for expression in a prokaryotic host are described comprising gas vesicle assembly (GVA) genes native to a GVA prokaryotic species and capable of being expressed in a functional form in the prokaryotic host, and one or more gas vesicle structural (GVS) genes native to one or more GVS prokaryotic species, at least one of the one or more GVS prokaryotic species different from the GVA prokaryotic species, and related gas vesicle reporting (GVR) genetic circuits, genetic, vectors, engineered cells, and related compositions methods and systems to produce GVs, hybrid GVGC and/or image a target site.
FILED Friday, July 28, 2017
APPL NO 15/663635
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/223 (20130101)
A61K 49/1896 (20130101)

Peptides
C07K 14/32 (20130101)
C07K 14/195 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/70 (20130101)
C12N 15/74 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/10 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118220 Daugharthy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of General Medical Sciences (NIGMS)
National Institute of Mental Health (NIMH)
U.S. Public Health Service (USPHS)
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Evan R. Daugharthy (Cambridge, Massachusetts);  Richard C. Terry (Carlisle, Massachusetts);  Je-hyuk Lee (Allston, Massachusetts);  George M. Church (Brookline, Massachusetts);  Benjamin W. Pruitt (Cambridge, Massachusetts)
ABSTRACT Methods of volumetric imaging of a three-dimensional matrix of nucleic acids within a cell is provided. An automated apparatus for sequencing and volumetric imaging of a three-dimensional matrix of nucleic acids is provided.
FILED Wednesday, April 17, 2019
APPL NO 16/386337
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/68 (20130101)
C12Q 1/6841 (20130101)
C12Q 1/6841 (20130101)
C12Q 1/6869 (20130101) Original (OR) Class
C12Q 1/6869 (20130101)
C12Q 2543/101 (20130101)
C12Q 2543/101 (20130101)
C12Q 2563/159 (20130101)
C12Q 2563/159 (20130101)
C12Q 2565/601 (20130101)
C12Q 2565/601 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118225 Salk et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute on Aging (NIA)
APPLICANT(S) UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington)
ASSIGNEE(S) UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington)
INVENTOR(S) Jesse Salk (Seattle, Washington);  Lawrence A. Loeb (Bellevue, Washington);  Michael Schmitt (Seattle, Washington)
ABSTRACT Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand. This method uniquely capitalizes on the redundant information stored in double-stranded DNA, thus overcoming technical limitations of prior methods utilizing data from only one of the two strands.
FILED Monday, August 31, 2020
APPL NO 17/008395
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101)
C12Q 1/6806 (20130101)
C12Q 1/6869 (20130101)
C12Q 1/6869 (20130101)
C12Q 1/6876 (20130101) Original (OR) Class
C12Q 2525/179 (20130101)
C12Q 2525/185 (20130101)
C12Q 2525/191 (20130101)
C12Q 2525/191 (20130101)
C12Q 2535/119 (20130101)
C12Q 2535/119 (20130101)
C12Q 2535/122 (20130101)
C12Q 2563/179 (20130101)
C12Q 2565/514 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118235 Bowers et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (Phoenix, Arizona);  ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY (Flagstaff, Arizona)
ASSIGNEE(S) The Translational Genomics Research Institute (Phoenix, Arizona);  Arizona Board of Regents on Behalf of Northern Arizona University (Flagstaff, Arizona)
INVENTOR(S) Jolene Bowers (Flagstaff, Arizona);  Elizabeth Driebe (Flagstaff, Arizona);  David Engelthaler (Flagstaff, Arizona);  Paul Keim (Flagstaff, Arizona)
ABSTRACT Embodiments of the invention provide a method of detecting one or more strains of Klebsiella pneumoniae. The method may include forming a plurality of mixtures for nucleic amplification. The method can include amplification of specific sequences within the K. pneumonia genome that can provide definitive information to distinguish between one or more types or strains of K. pneumonia.
FILED Friday, February 22, 2019
APPL NO 16/283232
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/689 (20130101) Original (OR) Class
C12Q 2600/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119054 Lindner et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania)
ASSIGNEE(S) THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania)
INVENTOR(S) Scott Eugene Lindner (State College, Pennsylvania);  Susan Hafenstein (Lemont, Pennsylvania)
ABSTRACT Provided are processes and materials for solving biological or structural information about proteins or other organic molecules. The processes capitalize on a rigid multimeric nanocage formed from self-assembling substructure proteins. The processes and materials allow for recognition and tight, optionally covalent, bonding of any protein molecule with a tag complementary to a capture sequence on the nanocage. The processes and materials may be used to obtain biological or structural information by cryo-electron microscopy and overcome prior limitations of target protein size or salt concentration.
FILED Friday, March 16, 2018
APPL NO 16/494502
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 1/00 (20130101)
C07K 14/47 (20130101)
C07K 2319/23 (20130101)
C07K 2319/50 (20130101)
C07K 2319/80 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/04 (20130101) Original (OR) Class
G01N 2223/612 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119061 Yu et al.
FUNDED BY
Department of Health and Human Services (HHS)
Food and Drug Administration (FDA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland)
ASSIGNEE(S) UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland)
INVENTOR(S) Yihua Bruce Yu (Ellicott City, Maryland);  Marc Taraban (Gaithersburg, Maryland);  Yue Feng (Niantic, Connecticut)
ABSTRACT The present invention generally relates to a method of using NMR relaxation rates (R2) of water molecules as an indicator of the extent of aggregation of biopharmaceutical formulations. The biopharmaceutical can be evaluated nondestructively without the vial or container being opened or protective seal compromised (i.e., broken). The method is applicable to all biopharmaceuticals and the water signal obtained by magnetic resonance relaxometry is very strong and sensitive because water is used as the solvent and is present in high (>90%) concentrations in every biopharmaceutical formulation.
FILED Monday, July 27, 2020
APPL NO 16/939424
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 24/08 (20130101) Original (OR) Class
G01N 33/15 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/50 (20130101)
G01R 33/448 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119069 Ibrahim et al.
FUNDED BY
Department of Energy (DOE)
Battelle Memorial Institute (BATTELLE)
Pacific Northwest National Laboratory (PNNL)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S) BATTELLE MEMORIAL INSTITUTE (Richland, Washington)
INVENTOR(S) Yehia M. Ibrahim (West Richland, Washington);  Adam L. Hollerbach (Richland, Washington);  Ailin Li (Richland, Washington)
ABSTRACT An apparatus includes multiple levels of ion transport channels, with successive levels coupled by elevator channels. Efficient three dimensional packing provides long path lengths in practical volumes for ion mobility separation with high resolving power. Disclosed elevator configurations provide efficient routing of ion transport channels across levels with low ion loss, enabling ion mobility separation over 100 levels or more. Elevator configurations include (i) opposed traveling waves meeting at an elevator entrance, (ii) external elevator with a wrap-around electrode bank, (iii) external elevator with electrode banks on parallel extension plates, or (iv) elevator operating in surfing mode, in various combinations. Manufacture is aided by printed wiring boards, with interchangeable boards. Assembly with motherboard, spacer block(s), and alignment pins provides efficient distribution of electrode excitations and accurate reproducible positioning.
FILED Friday, October 25, 2019
APPL NO 16/664435
ART UNIT 2881 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/68 (20130101)
G01N 27/622 (20130101) Original (OR) Class

Electric Discharge Tubes or Discharge Lamps
H01J 49/061 (20130101)
H01J 49/062 (20130101)
H01J 49/4225 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119081 Cooks et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Robert Graham Cooks (West Lafayette, Indiana);  Zheng Ouyang (West Lafayette, Indiana)
ABSTRACT The invention generally relates to ion generation using modified wetted porous materials. In certain aspects, the invention generally relates to systems and methods for ion generation using a wetted porous substrate that substantially prevents diffusion of sample into the substrate. In other aspects, the invention generally relate to ion generation using a wetted porous material and a drying agent. In other aspects, the invention generally relates to ion generation using a modified wetted porous substrate in which at least a portion of the porous substrate includes a material that modifies an interaction between a sample and the substrate.
FILED Thursday, June 18, 2020
APPL NO 16/905193
ART UNIT 2881 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 30/91 (20130101)
G01N 30/95 (20130101) Original (OR) Class
G01N 33/49 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 49/0031 (20130101)
H01J 49/167 (20130101)
H01J 49/168 (20130101)
H01J 49/0404 (20130101)
H01J 49/0409 (20130101)
H01J 49/0431 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119089 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
ASSIGNEE(S) Arizona Board of Regents on behalf of Arizona (Scottsdale, Arizona)
INVENTOR(S) Peiming Zhang (Gilbert, Arizona);  Sovan Biswas (Tempe, Arizona);  Suman Sen (Tempe, Arizona);  Stuart Lindsay (Phoenix, Arizona)
ABSTRACT The present disclosure provides apparatus and methods for determining the sequence of a nucleic acid. The apparatus comprises electrodes that form a tunnel gap through which the nucleic acid can pass. The electrodes comprise a reagent that is capable of selectively interacting with a nucleobase of the nucleic acid sequence. When the reagent interacts with a nucleobase, a detectable signal is produced and used to identify the nucleobase of the nucleic acid. Advantageously, the apparatus of this disclosure is specific to identifying nucleic acids.
FILED Monday, August 21, 2017
APPL NO 16/327232
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 321/10 (20130101)
C07C 2603/50 (20170501)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6869 (20130101)
C12Q 1/6869 (20130101)
C12Q 2563/116 (20130101)
C12Q 2563/157 (20130101)
C12Q 2565/607 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/48721 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119098 Swager et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Timothy M. Swager (Newton, Massachusetts);  Qifan Zhang (Cambridge, Massachusetts)
ABSTRACT Embodiments described herein may be useful in the detection of analytes. The systems and methods may allow for a relatively simple and rapid way for detecting analytes such as chemical and/or biological analytes and may be useful in numerous applications including sensing, food manufacturing, medical diagnostics, performance materials, dynamic lenses, water monitoring, environmental monitoring, detection of proteins, detection of DNA, among other applications. For example, the systems and methods described herein may be used for determining the presence of a contaminant such as bacteria (e.g., detecting pathogenic bacteria in food and water samples which helps to prevent widespread infection, illness, and even death). Advantageously, the systems and methods described herein may not have the drawbacks in current detection technologies including, for example, relatively high costs, long enrichment steps and analysis times, and/or the need for extensive user training. Another advantageous feature provided by the systems and methods described herein includes fabrication in a relatively large scale. In some embodiments, the systems and methods may be used in conjunction with a detector including handheld detectors incorporated with, for example, smartphones (e.g., for the on-site detection of analytes such as pathogenic bacteria).
FILED Tuesday, November 27, 2018
APPL NO 16/201961
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6816 (20130101)
C12Q 1/6816 (20130101)
C12Q 1/6834 (20130101)
C12Q 2527/125 (20130101)
C12Q 2563/159 (20130101)
C12Q 2565/629 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/59 (20130101)
G01N 21/77 (20130101)
G01N 21/78 (20130101)
G01N 33/5432 (20130101) Original (OR) Class
G01N 33/54326 (20130101)
G01N 33/54366 (20130101)
G01N 2021/7783 (20130101)
G01N 2201/0221 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119104 Barasch et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Jonathan Barasch (New York, New York);  Katherine Xu (New York, New York);  Paul Rosenstiel (New York, New York);  Paolo Guarnieri (New York, New York)
ABSTRACT The present invention provides methods for treatment of volume-dependent Acute Kidney Injury (vAKI) and ischemic Acute Kidney Injury (iAKI), as well as methods for diagnosing vAKI and iAKI. The methods are based on determining the levels of PAPPA2, NGAL, KRT20, or TACSTD2 protein in a sample from a patient, such as a urine sample. The present invention also provides a device and a diagnostics kit for determining whether a sample from a subject contains PAPPA2, NGAL, KRT20, or TACSTD2 protein.
FILED Friday, August 12, 2016
APPL NO 15/752230
ART UNIT 1699 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/68 (20130101)
G01N 33/70 (20130101)
G01N 33/573 (20130101) Original (OR) Class
G01N 33/6893 (20130101)
G01N 2333/96486 (20130101)
G01N 2800/347 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119165 Nevzorov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
APPLICANT(S) North Carolina State University (Raleigh, North Carolina)
ASSIGNEE(S) North Carolina State University Office of Research Commercialization (Raleigh, North Carolina)
INVENTOR(S) Alexander Nevzorov (Raleigh, North Carolina);  Alexej I. Smirnov (Raleigh, North Carolina);  Sergey Milikisiyants (Raleigh, North Carolina)
ABSTRACT Aspects of photonic band gap resonators for magnetic resonance are described. In one example, an apparatus includes a 1D structure having a plurality of layers. A respective thickness of the individual layers is one-quarter of a respective wavelength of a target magnetic resonance frequency within the individual layers of the plurality of layers, or a multiple thereof. A first layer has a first dielectric constant, and a second layer that is adjacent to the first layer has a second dielectric constant. A defect includes a sample. The defect has a thickness that is approximately up to one-half of a wavelength of the target magnetic resonance frequency within the defect.
FILED Wednesday, June 27, 2018
APPL NO 16/626714
ART UNIT 2866 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/30 (20130101)
G01R 33/341 (20130101)
G01R 33/34007 (20130101) Original (OR) Class
G01R 33/34069 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11120253 Yu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S) Stowers Institute for Medical Research (Kansas City, Missouri)
ASSIGNEE(S) Stowers Institute for Medical Research (Kansas City, Missouri)
INVENTOR(S) Congrong (Ron) Yu (Leawood, Kansas);  Rishabh Raj (Kansas City, Missouri);  Dar Wilbur Dahlen (Albany, California)
ABSTRACT This disclosure relates to the use of “pseudo-images” to perform image recognition, e.g., to perform facial image recognition. In an embodiment, the pseudo-image is obtained by starting with a real world image and, after optional preprocessing, subjecting the image to a non-linear transformation that converts the image into a pseudo-image. While real world objects (or, more generally, real world patterns) may be perceivable in the starting image, they cannot be perceived in the pseudo-image. Image recognition takes place by comparing the pseudo-image with a library of known pseudo-images, i.e., image recognition takes place in pseudo-image space without a return to real world space. In this way, robust image recognition is achieved even for imperfect real world images, such as, real world images that have been degraded by noise, poor illumination, uneven lighting, and/or occlusion, e.g., the presence of glasses, scarves, or the like in the case of facial images.
FILED Wednesday, June 26, 2019
APPL NO 16/453545
ART UNIT 2631 — Digital Communications
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/40 (20130101)
G06K 9/00275 (20130101)
G06K 9/00288 (20130101) Original (OR) Class
G06K 9/4652 (20130101)
G06K 9/4661 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11120307 Xie
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York)
ASSIGNEE(S) MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York)
INVENTOR(S) Chensu Xie (New York, New York)
ABSTRACT Presented herein are systems and methods for feature detection in images. A computing system may identify a biomedical image having features. The computing system may apply the biomedical image to a feature detection model. The feature detection model may include an encoder-decoder block to generate a feature map corresponding to the biomedical image, a confidence map generator having a second set of parameters to generate a confidence map using the feature map, and a localization map generator to generate a localization map using the feature map. The computing system may generate a resultant map based on the confidence map and the localization map. The resultant map identifying one or more points corresponding to the one or more features. The computing system may provide the one or more points identified in the resultant map for the biomedical image.
FILED Monday, August 24, 2020
APPL NO 17/001524
ART UNIT 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/0014 (20130101)
G06K 9/6232 (20130101)
G06K 9/6265 (20130101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 7/0012 (20130101)
G06T 2207/10056 (20130101)
G06T 2207/30061 (20130101)
G06T 2207/30068 (20130101)
G06T 2207/30096 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11120548 Wilson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S) Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S) David L. Wilson (Cleveland Heights, Ohio);  David Prabhu (Dublin, Ohio);  Chaitanya Kolluru (Cleveland, Ohio);  Yazan Gharaibeh (Cleveland, Ohio);  Hiram G. Bezerra (Cleveland, Ohio);  Hao Wu (Cleveland, Ohio)
ABSTRACT Embodiments discussed herein facilitate classification of vascular plaque. One example embodiment can: access vascular imaging data comprising one or more slices, wherein each slice comprises a plurality of A-lines of that slice; for each A-line of the plurality of A-lines of each slice of the one or more slices: extract one or more features for that A-line, wherein the one or more features for that A-line comprise at least one of: one or more features extracted from that A-line, one or more features extracted from the slice comprising that A-line, or one or more features extracted from the vascular imaging data; provide the one or more features for that A-line to at least one classifier; and generate a classification of that A-line via the at least one classifier, wherein the classification of that A-line is one of fibrocalcific, fibrolipidic, or other.
FILED Monday, February 10, 2020
APPL NO 16/786058
ART UNIT 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/628 (20130101)
G06K 9/6232 (20130101)
G06K 9/6262 (20130101)
G06K 9/6269 (20130101)

Computer Systems Based on Specific Computational Models
G06N 5/003 (20130101)
G06N 20/10 (20190101)

Image Data Processing or Generation, in General
G06T 5/20 (20130101)
G06T 7/0012 (20130101) Original (OR) Class
G06T 2207/10064 (20130101)
G06T 2207/10101 (20130101)
G06T 2207/10132 (20130101)
G06T 2207/20081 (20130101)
G06T 2207/30101 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11120889 Fine et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia)
INVENTOR(S) Eli Fine (Atlanta, Georgia);  Thomas J. Cradick (Atlanta, Georgia);  Yanni Lin (Atlanta, Georgia);  Gang Bao (Mabelton, Georgia)
ABSTRACT Endonucleases play an essential role in genetic engineering and molecular biology. A major barrier to the clinical adoption of nucleases and engineered nucleases remain the overall lack of specificity and activity. Off-site cleavage, cleavage at loci other than the target loci, typically occurs resulting in mutations, unexpected gene-knockouts, or translocations. Provided herein are systems and methods for identifying the off-site cleavage loci and predicting the activity of engineered endonucleases for a given genome. It is expected that these tools and methods will be useful for designing nucleases and other related DNA binding domains (e.g. TAL effectors) for genomic therapy and engineering.
FILED Friday, March 15, 2013
APPL NO 14/399837
ART UNIT 3619 — Semiconductors/Memory
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 20/00 (20190201) Original (OR) Class
G16B 30/00 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 11116740 Venn-Watson
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Secretary of the Navy (SECNAV)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (San Diego, California)
ASSIGNEE(S) United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Stephanie Venn-Watson (San Diego, California)
ABSTRACT Compositions including an odd chain fatty acid, and salts and derivatives thereof, and methods for metabolic syndrome treatment and prophylaxis are provided, including compositions and methods for treating diabetes, obesity, hyperferritinemia, elevated insulin, glucose intolerance, dyslipidemia and related conditions. Methods for the diagnosis and monitoring of metabolic syndrome are also provided.
FILED Wednesday, August 07, 2019
APPL NO 16/534382
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/20 (20130101) Original (OR) Class
A61K 31/201 (20130101)
A61K 31/202 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/92 (20130101)
G01N 2405/00 (20130101)
G01N 2800/04 (20130101)
G01N 2800/22 (20130101)
G01N 2800/042 (20130101)
G01N 2800/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116827 Jones et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Materiel Development Activity (USAMMDA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) ETUBICS CORPORATION (Seattle, Washington)
ASSIGNEE(S) Etubics Corporation (Seattle, Washington)
INVENTOR(S) Frank R. Jones (Seattle, Washington);  Joseph Balint (Seattle, Washington);  Elizabeth Gabitzsch (Seattle, Washington)
ABSTRACT In certain embodiments, methods and compositions are provided for generating immune responses against tumor antigens such as antigens or epitopes of HER1, HER2/neu, HER3, HER4, or any combination thereof. In particular embodiments, there may be provided methods for constructing and producing recombinant adenovirus-based vector vaccines containing nucleic acid sequences encoding tumor antigens such as antigens or epitopes of HER1, HER2/neu, HER3, HER4, or any combination thereof, that allow for vaccinations in individuals with preexisting immunity to adenovirus.
FILED Saturday, June 02, 2018
APPL NO 16/615925
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/00117 (20180801)
A61K 39/001106 (20180801) Original (OR) Class
A61K 39/001152 (20180801)
A61K 2039/523 (20130101)

Peptides
C07K 16/2827 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
C12N 2710/10343 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116870 Francis et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) EMBODY INC. (Norfolk, Virginia)
ASSIGNEE(S) EMBODY INC. (Norfolk, Virginia)
INVENTOR(S) Michael Francis (Norfolk, Virginia);  Nathan Kemper (Norfolk, Virginia);  Hilary Wriggers (Norfolk, Virginia)
ABSTRACT Compositions and blends of biopolymers and copolymers are described, along with their use to prepare biocompatible scaffolds and surgically implantable devices for use in supporting and facilitating the repair of soft tissue injuries.
FILED Tuesday, June 23, 2020
APPL NO 16/909058
ART UNIT 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0024 (20130101)
A61K 38/39 (20130101)
A61K 47/34 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/18 (20130101) Original (OR) Class
A61L 27/24 (20130101)
A61L 27/26 (20130101)
A61L 27/26 (20130101)
A61L 27/26 (20130101)
A61L 27/44 (20130101)
A61L 27/54 (20130101)
A61L 27/58 (20130101)
A61L 27/386 (20130101)
A61L 27/3804 (20130101)
A61L 2300/64 (20130101)
A61L 2300/604 (20130101)
A61L 2400/12 (20130101)
A61L 2430/10 (20130101)
A61L 2430/34 (20130101)

Compositions of Macromolecular Compounds
C08L 67/04 (20130101)
C08L 89/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116902 El-Khatib et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) BETA BIONICS, INC. (Concord, Massachusetts)
ASSIGNEE(S) Beta Bionics, Inc. (Concord, Massachusetts)
INVENTOR(S) Firas H. El-Khatib (Allston, Massachusetts);  Edward R. Damiano (Acton, Massachusetts)
ABSTRACT A blood glucose control system is configured to modify therapy provided to a subject. The system can cause first therapy to be delivered by the blood glucose control system to a subject during a first therapy period. The first therapy can be delivered based at least in part on a first value of a control parameter used by a control algorithm to generate a dose control signal. The system can determine a first effect corresponding at least in part to the first therapy and autonomously generate a second value of the control parameter. The system can cause second therapy to be delivered by the blood glucose control system to the subject during a second therapy period, wherein the second therapy is delivered based at least in part on the second value of the control parameter.
FILED Friday, October 02, 2020
APPL NO 17/061927
ART UNIT 3783 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 5/1723 (20130101) Original (OR) Class
A61M 5/14244 (20130101)
A61M 2005/1726 (20130101)
A61M 2005/14208 (20130101)
A61M 2205/16 (20130101)
A61M 2205/50 (20130101)
A61M 2205/52 (20130101)
A61M 2205/502 (20130101)
A61M 2205/505 (20130101)
A61M 2205/3553 (20130101)
A61M 2205/3561 (20130101)
A61M 2205/3584 (20130101)
A61M 2205/3592 (20130101)
A61M 2230/201 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 10/40 (20180101)
G16H 20/17 (20180101)
G16H 20/60 (20180101)
G16H 40/67 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116964 McLaughlin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
Army Research Laboratory (ARL)
Aberdeen Proving Ground (APG)
Army Research Office (ARO)
APPLICANT(S) Micro-Leads, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Micro-Leads, Inc. (Boston, Massachusetts)
INVENTOR(S) Bryan L. McLaughlin (Cambridge, Massachusetts);  Girish Chitnis (Watertown, Massachusetts);  John Ogren (Antrim, New Hampshire)
ABSTRACT An electrode array system includes a unitary body forming a plurality of apertures, and a plurality of continuous conductive elements at least partially encapsulated within the unitary body. The continuous conductive elements include/form a plurality of contacts, a plurality of electrode sites configured to couple with neural tissue (e.g., a spinal nerve or peripheral nerve), and a plurality of interconnects extending between the plurality of contacts and the plurality of electrode sites. The plurality of electrode sites are aligned with the plurality of apertures, and the plurality of apertures expose the plurality of electrodes.
FILED Tuesday, November 07, 2017
APPL NO 15/806005
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0534 (20130101)
A61N 1/0553 (20130101) Original (OR) Class
A61N 1/0556 (20130101)
A61N 1/0558 (20130101)
A61N 1/36062 (20170801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116976 Edgerton et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
United States Army (USA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) The Regents of the University of California (Oakland, California);  California Institute of Technology (Pasadena, California);  University of Louisville Research Foundation, Inc. (Louisville, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Victor Reggie Edgerton (Los Angeles, California);  Roland R. Roy (Playa Vista, California);  Yury Gerasimenko (Los Angeles, California);  Joel W. Burdick (Pasadena, California);  Susan J. Harkema (Louisville, California);  Jonathan Hodes (Louisville, Kentucky);  Yu-Chong Tai (Pasadena, California);  Mandheerej S. Nandra (Pasadena, California);  Claudia A. Angeli (Louisville, Kentucky);  Thomas Anthony Desautels (Pasadena, California)
ABSTRACT Methods comprising applying electrical stimulation to patients in conjunction with physical training are described.
FILED Tuesday, January 23, 2018
APPL NO 15/878325
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body
A61H 1/0237 (20130101)
A61H 1/0274 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0551 (20130101)
A61N 1/0553 (20130101)
A61N 1/0556 (20130101)
A61N 1/3616 (20130101)
A61N 1/36003 (20130101)
A61N 1/36103 (20130101) Original (OR) Class

Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment
A63B 21/00181 (20130101)
A63B 22/0235 (20130101)
A63B 69/0064 (20130101)
A63B 2213/004 (20130101)
A63B 2220/805 (20130101)
A63B 2230/60 (20130101)

Rotary-piston, or Oscillating-piston, Positive-displacement Machines for Liquids; Rotary-piston, or Oscillating-piston, Positive-displacement Pumps
F04C 2270/0421 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117008 Ananth et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Secretary of the Navy (SECNAV)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Ramagopal Ananth (Bryn Mawr, Pennsylvania);  Arthur W. Snow (Alexandria, Virginia);  Katherine Hinnant (Washington, District of Columbia);  Spencer L. Giles (Lorton, Virginia)
ABSTRACT Disclosed is a firefighting composition of the surfactants below and water. The values of m, n, x, and y are independently selected positive integers. R is an organic group. R′ is a siloxane group.
FILED Monday, March 18, 2019
APPL NO 16/356254
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Fire-fighting
A62C 5/02 (20130101)

Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus
A62D 1/0071 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117206 Grogan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
U.S. Navy
APPLICANT(S) Powdermet, Inc. (Euclid, Ohio)
ASSIGNEE(S) Powdermet, Inc. (Euclid, Ohio)
INVENTOR(S) Mark Grogan (Cleveland, Ohio);  Brian Doud (Cleveland Heights, Ohio);  Andrew Sherman (Mentor, Ohio)
ABSTRACT A heterogeneous composite consisting of near-nano ceramic clusters dispersed within a ductile matrix. The composite is formed through the high temperature compaction of a starting powder consisting of a core of ceramic nanoparticles held together with metallic binder. This core is clad with a ductile metal such that when the final powder is consolidated, the ductile metal forms a tough, near-zero contiguity matrix. The material is consolidated using any means that will maintain its heterogeneous structure.
FILED Thursday, November 16, 2017
APPL NO 15/814936
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/025 (20130101)
B22F 3/14 (20130101)
B22F 3/15 (20130101)
B22F 3/17 (20130101)
B22F 3/18 (20130101)
B22F 3/20 (20130101)
B22F 3/24 (20130101)
B22F 3/105 (20130101)

Working of Metal by the Action of a High Concentration of Electric Current on a Workpiece Using an Electrode Which Takes the Place of a Tool; Such Working Combined With Other Forms of Working of Metal
B23H 1/08 (20130101)
B23H 5/04 (20130101)
B23H 5/12 (20130101) Original (OR) Class
B23H 7/00 (20130101)

Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools
B23P 13/02 (20130101)

Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/5626 (20130101)
C04B 35/58014 (20130101)

Alloys
C22C 29/00 (20130101)
C22C 32/00 (20130101)

Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings
F16C 17/00 (20130101)
F16C 19/00 (20130101)
F16C 33/00 (20130101)
F16C 33/043 (20130101)
F16C 2206/80 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117243 Brown et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Secretary of the Navy (SECNAV)
APPLICANT(S) The United States of America As Represented by the Secretary of Navy (Indian Head, Maryland)
ASSIGNEE(S) The United States of American as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Lance A. Brown (King George, Virginia);  David G. Banks (White Plains, Maryland);  Keith Chamberlain (Waldorf, Maryland);  Lonnie Frericks (King George, Virginia);  Scott Steward (Accokeek, Maryland)
ABSTRACT A multi-tool for disrupter breech maintenance includes an elongate body having a first axial end and a second axial end. The elongate body encases a storage volume commencing at and accessible from the second axial end. An open-ended rectangular notch in a radial wall of the elongate body has a planar base. A hole extends radially through the elongate body with the hole originating in the notch's planar base and having a longitudinal axis perpendicular to the planar base. A rectangular well in the radial wall of the elongate body is provided adjacent to the rectangular notch. A first hexagonal socket is coupled to the first axial end of the elongate body. A second hexagonal socket is provided for attachment to the second axial end of the elongate body.
FILED Wednesday, May 01, 2019
APPL NO 16/501560
ART UNIT 3723 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Tools or Bench Devices Not Otherwise Provided For, for Fastening, Connecting, Disengaging or Holding
B25B 13/48 (20130101)
B25B 13/065 (20130101) Original (OR) Class

Handles for Hand Implements
B25G 1/085 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117666 Groen
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Skyworks Global Inc. (Salt Lake City, Utah)
ASSIGNEE(S) Skyworks Aeronautics Corp. (Salt Lake City, Utah)
INVENTOR(S) David Groen (Murray, Utah)
ABSTRACT A precision delivery vehicle having a vehicle body assembly, a fixed wing system, a rotor system and a guidance system. The vehicle body assembly can retain a payload. The fixed wing system includes first and second wings coupled to the vehicle body for fixed wing flight. The rotor system includes a mast structure, a rotor hub rotatable about the mast structure and at least two rotor blades coupled to the rotor hub and rotatable with the rotor hub relative to the mast structure. The at least two rotor blades are movable between a collapsed configuration and a deployed configuration. In the collapsed configuration, the precision delivery vehicle is in fixed wing flight. Upon placement of the at least two rotor blades into the deployed configuration, the precision delivery vehicle is placed into rotative flight. The guidance system is structurally configured to direct the precision delivery vehicle to a target.
FILED Wednesday, March 28, 2018
APPL NO 15/938227
ART UNIT 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeroplanes; Helicopters
B64C 3/56 (20130101)
B64C 29/02 (20130101)
B64C 39/024 (20130101)
B64C 2201/102 (20130101)
B64C 2201/108 (20130101)
B64C 2201/128 (20130101)
B64C 2201/206 (20130101)

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 1/12 (20130101) Original (OR) Class
B64D 17/80 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117667 McGann et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Secretary of the Navy (SECNAV)
APPLICANT(S) The United States of America as Represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Shawn Kerry McGann (Ridgecrest, California);  Nicholas McGaha (Ridgecrest, California)
ABSTRACT An unmanned aerial vehicle (UAV) jettison apparatus. The UAV jettison apparatus may comprise a payload bay, fairing, ejector plate, and releasable latch. The payload bay may be mounted beneath an aircraft and may have an inner space and a top plate attached therewith. The fairing may substantially cover the inner space of the payload bay and may have an opening positioned directly below the top plate. The ejector plate, which may be spring-loaded, may substantially cover the opening and may be used to mount the UAV. The releasable latch, which may be disposed between the top plate and the ejector plate, may releasably lock and hold the UAV in a stowed position and, upon release, may allow the ejector plate to move into a launch position, such that the UAV is released and jettisoned from a larger aircraft.
FILED Monday, November 05, 2018
APPL NO 16/180425
ART UNIT 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeroplanes; Helicopters
B64C 7/00 (20130101)
B64C 39/024 (20130101)
B64C 2201/082 (20130101)
B64C 2201/206 (20130101)

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 1/02 (20130101)
B64D 5/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117847 Harvey
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Secretary of the Navy (SECNAV)
APPLICANT(S) The United States of America, as Represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Benjamin G. Harvey (Ridgecrest, California)
ABSTRACT In the present method a reaction mixture is comprised of a source of adamantane, mixed with an alkane or cycloalkane. A Lewis acid catalyst is added to the reaction mixture which is heated and then purified. The resulting alkyl diamondoid mixtures have significantly higher densities and volumetric net heats of combustion while maintaining low viscosities which allow for use at low temperature.
FILED Friday, March 29, 2019
APPL NO 16/369829
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 2/74 (20130101) Original (OR) Class
C07C 7/04 (20130101)
C07C 7/005 (20130101)
C07C 7/14 (20130101)
C07C 13/615 (20130101)
C07C 2603/74 (20170501)

Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters
C10L 1/08 (20130101)
C10L 2270/04 (20130101)
C10L 2270/026 (20130101)
C10L 2290/543 (20130101)
C10L 2290/544 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118002 Davis
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Secretary of the Navy (SECNAV)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Matthew C. Davis (Ridgecrest, California)
ABSTRACT The invention generally relates to novel poly-substituted cis stilbenes, their synthesis, their purification, and their use in thermoset resins. These novel cis stilbenes give rise to thermoset resins with greatly improved processing characteristics such as lower melting temperature and lower viscosity; resulting in polymers and composites having greatly improved thermal stability.
FILED Monday, April 20, 2020
APPL NO 16/853260
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 18/7685 (20130101) Original (OR) Class
C08G 63/193 (20130101)
C08G 65/42 (20130101)
C08G 2650/62 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118048 Macfarlane et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Robert J. Macfarlane (Cambridge, Massachusetts);  Jianyuan Zhang (Cambridge, Massachusetts);  Peter Jeffries Santos (Cambridge, Massachusetts);  Paul Anthony Gabrys (Cambridge, Massachusetts)
ABSTRACT Nanostructures and associated compositions, systems, and methods are provided. In some embodiments, a nanostructure may comprise polymers, intermolecular bonding groups, and a particle. The polymers may be associated with the particle and the intermolecular bonding groups may be associated with at least some of the polymers. In some embodiments, at least some of the intermolecular bonding groups may have a different chemical composition and/or chemical property than the polymers. In some embodiments, nanostructures may reversibly associate with each other via the intermolecular bonding groups to form a material. In some such cases, the intermolecular bonding groups on different nanostructures may reversibly associate with each other. In some embodiments, the nanostructures may be designed, such that the energy required to disassociate at least a portion of the nanostructures in the material is greater than the energy required to dissociate a single association between intermolecular bonding groups.
FILED Thursday, September 21, 2017
APPL NO 16/335483
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)
B82Y 40/00 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 2438/00 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/16 (20130101)
C08K 3/22 (20130101)

Compositions of Macromolecular Compounds
C08L 51/00 (20130101)
C08L 51/10 (20130101) Original (OR) Class
C08L 2207/53 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118124 Harvey et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Secretary of the Navy (SECNAV)
APPLICANT(S) The United States of America, as Represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Benjamin G. Harvey (China Lake, California);  Matthew C. Davis (China Lake, California)
ABSTRACT A diamondoid fuel comprising a cage structure including 10, 14, 18, or 22 carbons. The diamondoid fuel also includes one of one to four cyclopropyl groups bonded to the cage structure or two to four functional groups bonded to the cage structure where the functional groups are an alkyl group, an allyl group, a cyclopropyl group, or combinations thereof. Additionally, at least one functional group is an allyl group and at least one functional group is a cyclopropyl group.
FILED Monday, October 07, 2019
APPL NO 16/595101
ART UNIT 1796 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 15/38 (20130101)
C07C 2603/74 (20170501)

Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters
C10L 1/04 (20130101) Original (OR) Class
C10L 7/02 (20130101)
C10L 2200/0407 (20130101)
C10L 2250/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118162 Humes et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) SeaStar Medical, Inc. (Cardiff-By-The-Sea, California)
ASSIGNEE(S) SeaStar Medical, Inc. (Denver, Colorado)
INVENTOR(S) H. David Humes (Ann Arbor, Michigan);  Deborah A. Buffington (Ann Arbor, Michigan);  Christopher J. Pino (Saline, Michigan)
ABSTRACT The present invention relates to a cytopheretic cartridge for use in treating and/or preventing inflammatory conditions within a subject and to related methods. More particularly, the invention relates to a cytopheretic cartridge that includes a housing and, disposed within the housing, a solid support capable of sequestering activated leukocytes and/or platelets.
FILED Monday, July 31, 2017
APPL NO 15/664884
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 1/1698 (20130101)
A61M 1/3672 (20130101)
A61M 1/3675 (20130101)
A61M 1/3679 (20130101)
A61M 2202/0427 (20130101)
A61M 2202/0439 (20130101)

Separation
B01D 63/02 (20130101)
B01D 2313/44 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0634 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118170 Pavlik et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
APPLICANT(S) Board of Regents of the University of Nebraska (Lincoln, Nebraska)
ASSIGNEE(S) The Board of Regents of the University of Nebraska (Lincoln, Nebraska)
INVENTOR(S) Benjamin J. Pavlik (Lincoln, Nebraska);  Paul Blum (Lincoln, Nebraska);  Kevin Van Cott (Hickman, Nebraska)
ABSTRACT An engineered payload-delivery system includes a target cell binding unit, covalently bound to a pore forming unit, and a payload portion adapted with a region capable of non-covalently binding to the pore forming unit. The pore forming unit is derived from a particular sub-serotype of Clostridium toxin, while the payload region is derived from a different sub-serotype of Clostridium toxin. The disclosed chimeric protein-based composition is capable of specifically delivering payload to neural cells.
FILED Tuesday, April 21, 2020
APPL NO 16/854551
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/45 (20130101)
A61K 47/6415 (20170801)
A61K 49/0056 (20130101)

Peptides
C07K 14/33 (20130101)
C07K 2319/33 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/52 (20130101) Original (OR) Class
C12N 15/62 (20130101)

Enzymes
C12Y 204/02 (20130101)
C12Y 304/24069 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118245 Berggren et al.
FUNDED BY
Department of Defense (DOD)
Defense Logistics Agency (DLA)
APPLICANT(S) Pioneer Astronautics (Lakewood, Colorado)
ASSIGNEE(S) Pioneer Astronautics (Lakewood, Colorado)
INVENTOR(S) Mark Berggren (Golden, Colorado);  Robert Zubrin (Golden, Colorado);  John T Henri (Longmont, Colorado);  Boris Nizamov (Highlands Ranch, Colorado)
ABSTRACT Novel methods of recovering neodymium and related rare earth elements from permanent magnets of various compositions are described. The methods employ processing steps including converting the magnet material to a higher surface area form such as a powder, treating the mixture with alkaline solutions to form product concentrated in neodymium and rare earth metals. Inexpensive materials such as ammonia, ammonium carbonate, carbon dioxide, water are recycled in a process that uses moderate temperatures, pressures and non-corrosive and environmentally-friendly chemicals.
FILED Friday, December 15, 2017
APPL NO 15/844127
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Production and Refining of Metals; Pretreatment of Raw Materials
C22B 1/005 (20130101)
C22B 3/44 (20130101)
C22B 7/008 (20130101)
C22B 59/00 (20130101) Original (OR) Class

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 10/20 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118270 Arumugam et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Research Laboratory (AFRL)
U.S. Air Force
APPLICANT(S) Oceanit Laboratories, Inc. (Honolulu, Hawaii)
ASSIGNEE(S) Oceanit Laboratories, Inc. (Honolulu, Hawaii)
INVENTOR(S) Ganesh Kumar Arumugam (Honolulu, Hawaii);  Vinod Veedu (Houston, Texas)
ABSTRACT A method for preparing an icephobic surface includes cleaning, etching and anodizing a target surface and applying fluorinated nanoparticles to the cleaned, etched and anodized target surface. A surface is treated according to this method.
FILED Tuesday, December 01, 2015
APPL NO 14/956375
ART UNIT 1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Processes for Applying Fluent Materials to Surfaces, in General
B05D 5/00 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 28/04 (20130101) Original (OR) Class
C23C 30/00 (20130101)

Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25
C23F 1/16 (20130101)

Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 11/02 (20130101)
C25D 11/04 (20130101)
C25D 11/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118273 Wilcox
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Secretary of the Navy (SECNAV)
APPLICANT(S) The United States of America, as Represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Benjamin Wilcox (Camarillo, California)
ABSTRACT A brine electrolysis system for producing pressurized chlorine and hydrogen gases. In its basic configuration, the brine electrolysis system may comprise: two liquid storage tanks for storing two liquid reactants; a tank having two interior spaces separated by a diaphragm for receiving the liquid reactants; two pumps for regulating the flow of the liquid reactants from the liquid storage tanks to the interior spaces of the tank, two open-bottom cylinders for storing and dispensing two gases; an electrolysis stack assembly for converting the liquid reactants into two gases; and two submersible pumps for pumping each liquid reactant into an electrolysis stack assembly. Each open-bottom cylinder may comprise a float sensor for determining the amount of fluid entering its cylindrical space. The system may further comprise controllers for regulating ionic concentrations within the two interior spaces. Dispense lines and valves may be utilized to release the gases.
FILED Tuesday, June 30, 2020
APPL NO 16/916320
ART UNIT 3617 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 1/46 (20130101) Original (OR) Class
C25B 9/23 (20210101)
C25B 15/02 (20130101)
C25B 15/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118471 Teixeira et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
United States Navy (USN)
APPLICANT(S) UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut)
ASSIGNEE(S) RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S) John D. Teixeira (Palm City, Florida);  Eric A. Grover (Tolland, Connecticut);  Raymond Surace (Newington, Connecticut)
ABSTRACT A gas turbine engine component includes an outer diameter endwall, an inner diameter endwall spaced radially inward of the outer diameter endwall, and at least one body supported between the outer and inner endwalls for rotation about an axis. The body includes an outer diameter surface spaced from the outer diameter endwall by a first gap and an inner diameter surface spaced from the inner diameter endwall by a second gap. The outer and inner diameter surfaces and the outer and inner diameter endwalls are configured such that the first and second gaps remain generally constant in size as the body rotates about the axis.
FILED Monday, October 20, 2014
APPL NO 15/027526
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/143 (20130101)
F01D 17/162 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2250/241 (20130101)
F05D 2250/711 (20130101)
F05D 2250/712 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 50/60 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118474 Propheter-Hinckley et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Research Laboratory (AFRL)
United States Air Force (USAF)
APPLICANT(S) UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
ASSIGNEE(S) Raytheon Technologies Corporation (Farmington, Connecticut)
INVENTOR(S) Tracy A. Propheter-Hinckley (Manchester, Connecticut);  Raymond Surace (Newington, Connecticut)
ABSTRACT A vane platform cooling system may comprise a combustor shell and a combustor panel. A cavity may be located between the combustor shell and the combustor panel. A surface of the cavity may be angled toward the combustor shell. An orifice may be formed in a vane platform located aft of the combustor panel. A standoff located in the cavity may direct air toward the vane platform. An aperture may be formed in a surface of the vane platform. A channel formed through the vane platform may connect the orifice and aperture.
FILED Monday, October 09, 2017
APPL NO 15/727816
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/141 (20130101)
F01D 5/147 (20130101)
F01D 5/186 (20130101)
F01D 5/187 (20130101)
F01D 9/041 (20130101)
F01D 25/12 (20130101) Original (OR) Class

Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 7/18 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2230/10 (20130101)
F05D 2230/21 (20130101)
F05D 2240/35 (20130101)
F05D 2240/81 (20130101)
F05D 2260/201 (20130101)
F05D 2260/202 (20130101)

Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers
F23R 3/002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118885 Williamson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Surface Warfare Center (NSWC)
Secretary of the Navy (SECNAV)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Crane, Indiana)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Christopher Williamson (Bloomfield, Indiana);  Lawrence Shirley (Bloomfield, Indiana)
ABSTRACT A portable item carrier and belt feed system is provided along with related methods. One illustrative embodiment includes a carrier and feed structure comprising a semi-rigid material with a divider support extending perpendicularly from a center floor section of the carrier. A belt of items is folded over the divider to reduce jams or misfeeds as the belt of items is pulled through a feed chute near an upper side section of the carrier and feed structure at a predetermined range of feed angles to the divider support. A latch disposed on a lid of the feed structure is configured for quick and easy access to the belt of items. A flexible outer container encloses the carrier and feed structure and can be coupled to a harness section configured to couple with a mobile structure. Additional embodiments include variants suitable for field manufacturing as well as portable manufacturing systems and methods.
FILED Thursday, June 25, 2015
APPL NO 14/750195
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Travelling or Camp Equipment: Sacks or Packs Carried on the Body
A45F 3/10 (20130101)
A45F 2003/045 (20130101)

Hand-held Nailing or Stapling Tools; Manually Operated Portable Stapling Tools
B25C 3/002 (20130101)

Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance
F41A 9/79 (20130101)

Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 39/02 (20130101) Original (OR) Class
F42B 39/08 (20130101)
F42B 39/26 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118886 Blazek et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Secretary of the Navy (SECNAV)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S)
INVENTOR(S) Benjamin M. Blazek (Ridgecrest, California);  Lee R. Hardt (Ridgecrest, California)
ABSTRACT Embodiments employ venting features and damping components both inside and concentric to a fuzewell to improve munition fuze survivability. Damping components are selected based on their densities, stiffness properties, and material strengths. A shock damping liner with longitudinal grooves is affixed to an inner surface of the fuzewell and envelops the fuze. A biased equivalent strength threaded shock damping ring is concentric about the outer surface of the fuzewell and attenuates shock between the outermost munition system layer (a munition case) and the fuzewell. The damping components' materials, orientations, and structural geometries provide increased damping, resulting in impedance mismatches across multiple interface surfaces in the munition, which reduces shock vibrational pressures and stresses transferred to the fuze.
FILED Thursday, June 04, 2020
APPL NO 16/892938
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 39/20 (20130101)

Ammunition Fuzes; Arming or Safety Means Therefor
F42C 19/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118909 Jankowski et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
U.S. Army Picatinny Arsenal (PICA)
Combat Capabilities Development Command Armaments Center (CCDCAC)
APPLICANT(S) Orbital Research Inc. (Cleveland, Ohio)
ASSIGNEE(S) Orbital Research Inc. (Cleveland, Ohio)
INVENTOR(S) Michael Jankowski (Winter Garden, Florida);  Edward J. Rapp (Cleveland Heights, Ohio)
ABSTRACT The present invention relates to systems and methods for providing location and guidance, and more particularly for providing location and guidance in environments where global position systems (GPS) are unavailable or unreliable (GPS denied and/or degraded environments). The present invention further relates to systems and methods for using inertial measurement units IMUs to provide location and guidance. More particularly, the present invention relates to the use of a series of low-accuracy or low-resolution IMUs, in combination, to provide high-accuracy or high-resolution location and guidance results. The present invention further relates to an electronics-control system for handing off control of the measurement and guidance of a body in flight between groups or subgroups of IMUs to alternate between high dynamic range/lower resolution and lower dynamic range/higher resolution measurement and guidance as the environment dictates.
FILED Tuesday, November 26, 2019
APPL NO 16/695449
ART UNIT 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 15/01 (20130101)
F42B 30/10 (20130101)

Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/16 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118981 Almasri et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Research Office (ARO)
National Science Foundation (NSF)
APPLICANT(S) The Curators of the University of Missouri (Columbia, Missouri)
ASSIGNEE(S) The Curators of the University of Missouri (Columbia, Missouri)
INVENTOR(S) Mahmoud Almasri (Columbia, Missouri);  Edward Kinzel (Columbia, Missouri)
ABSTRACT A metasurface integrated microbolometer having a sensing layer (e.g., SixGeyO1-x-y). The presence of the metasurface provides selectivity with respect to wavelength, polarization and angle-of-incidence. The presence of the metasurface into the microbolometer affects conversion of electromagnetic to thermal energy, thermal response, electrical integration of the microbolometer, and the tradeoff between resistivity and temperature coefficient of resistance, thereby allowing the ability to obtain a sensing with high temperature coefficient of resistance with lower resistivity values than that of films without the metasurface. The presence of the metasurface removes the need for a Fabry-Perot cavity.
FILED Wednesday, April 17, 2019
APPL NO 16/387514
ART UNIT 2884 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 5/20 (20130101) Original (OR) Class
G01J 5/58 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/16 (20130101)
H01L 37/025 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119042 Dutta et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Aveek Dutta (West Lafayette, Indiana);  Vladimir M. Shalaev (West Lafayette, Indiana);  Alexandra Boltasseva (West Lafayette, Indiana);  Esteban E. Marinero-Caceres (West Lafayette, Indiana)
ABSTRACT A system of writing to and reading from a magnetic nanostructure is disclosed which includes an opto-magnetic write arrangement including a polarizer configured to receive incident light and provide a circularly or linearly polarized light, wherein light polarization is controlled by the polarizer and its orientation with respect to polarization of the incident light, a nanomagnetic structure configured to receive the polarized light including a substrate, and a nanomagnetic stack including a nanomagnet, and a capping layer, wherein the nanomagnetic stack is configured to receive the polarized light and thereby switch orientation of a magnetic moment associated with the magnetic nanostructure whereby the magnetic moment direction specifies a bit value held in the magnetic structure, and a magnetic read arrangement, configured to receive and interpret an optical signal from the magnetic nanostructure indicating the magnetic moment orientation from the nanomagnetic stack.
FILED Tuesday, August 11, 2020
APPL NO 16/990754
ART UNIT 2886 — Optics
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 20/00 (20130101)
B82Y 35/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/01 (20130101)
G01N 21/553 (20130101) Original (OR) Class
G01N 2021/0162 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/1215 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119093 Ingber et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Army Research Office (ARO)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S) Donald E. Ingber (Boston, Massachusetts);  Kambez Hajipouran Benam (Cambridge, Massachusetts);  Remi Villenave (Boston, Massachusetts);  Geraldine A. Hamilton (Cambridge, Massachusetts);  Bryan Hassell (Cambridge, Massachusetts);  Christopher D. Hinojosa (Cambridge, Massachusetts);  Carolina Lucchesi (Westwood, Massachusetts)
ABSTRACT Provided herein relates to systems and methods for producing and using a body having a central channel separated by one or more membranes. The membrane(s) are configured to divide the central channel into at least one mesochannel and at least one microchannel. The height of the mesochannel is substantially greater than the height of the microchannel. A gaseous fluid can be applied through the mesochannel while a liquid fluid flowing through the microchannel. The systems and methods described herein can be used for various applications, including, e.g., growth and differentiation of primary cells such as human lung cells, as well as any other cells requiring low shear and/also stratified structures, or simulation of a microenvironment in living tissues and/or organs (to model physiology or disease states, and/or to identify therapeutic agents and/or vaccines). The systems and methods can also permit co-culture with one or more different cell types.
FILED Friday, December 19, 2014
APPL NO 15/105962
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 21/08 (20130101)
C12M 23/16 (20130101)
C12M 25/02 (20130101)
C12M 35/04 (20130101)
C12M 41/46 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5044 (20130101) Original (OR) Class
G01N 2800/122 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119099 Biris et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Materiel Development Activity (USAMMDA)
APPLICANT(S) BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas)
ASSIGNEE(S) BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas)
INVENTOR(S) Alexandru S. Biris (Little Rock, Arkansas);  Andrew G. Kumpuris (Little Rock, Arkansas);  Zeid Nima (Little Rock, Arkansas)
ABSTRACT A method of making a nanocomposite includes forming at least one gold nanorod; coating a silver layer on an outer surface of the gold nanorod; assembling a Raman reporter molecule layer on the coated silver layer; coating a pegylated layer on the assembled Raman reporter molecule layer; and conjugating the coated pegylated layer with an active layer, the active layer comprising at least one of a targeting molecule configured to bind to the target of interest and a functional molecule configured to interact with the target of interest.
FILED Tuesday, September 19, 2017
APPL NO 15/708841
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/658 (20130101)
G01N 33/54346 (20130101) Original (OR) Class
G01N 2800/28 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119114 Krueger et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Space Command (AFSPC)
Space Systems Command (SSC)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Space and Naval Warfare Systems (SPAWAR)
APPLICANT(S) Honeywell International Inc. (Morris Plains, New Jersey)
ASSIGNEE(S) Honeywell International Inc. (Charlotte, North Carolina)
INVENTOR(S) Neil Krueger (Saint Paul, Minnesota);  Matthew Puckett (Phoenix, Arizona);  Arthur Savchenko (Kirkland, Washington);  Chad Fertig (Bloomington, Minnesota);  Steven Tin (Plymouth, Minnesota);  Joshua Dorr (Minneapolis, Minnesota)
ABSTRACT This disclosure is related to devices, systems, and techniques for securing one or more mechanical structures to a frame of a proof mass assembly. For example, a system includes a light-emitting device configured to emit an optical signal, a circuit including a modulating device configured to modulate the optical signal to produce a modulated optical signal, and a mechanical assembly. The mechanical assembly includes an anchor structure including a set of connecting structures configured to pass the modulated optical signal, where the set of connecting structures includes two or more connecting structures, and where a width of each connecting structure of the set of connecting structures is less than a maximum width of the anchor structure and a mechanical structure intersecting with the anchor structure, the mechanical structure configured to guide the modulated optical signal.
FILED Wednesday, July 17, 2019
APPL NO 16/514864
ART UNIT 2861 — Printing/Measuring and Testing
CURRENT CPC
Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves
G01H 9/00 (20130101)

Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement
G01P 15/093 (20130101) Original (OR) Class
G01P 15/097 (20130101)
G01P 15/0802 (20130101)
G01P 2015/0814 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119115 Strehlow et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Honeywell International Inc. (Morris Plains, New Jersey)
ASSIGNEE(S) Honeywell International Inc. (Charlotte, North Carolina)
INVENTOR(S) John Strehlow (Mukilteo, Washington);  Mitchell Novack (Kenmore, Washington)
ABSTRACT A resonator defining a longitudinal axis that includes a mounting pad, a pad connector, at least one isolation mechanism, and a pair of elongated tines extending in the direction of the longitudinal axis. The isolation mechanism including an outer block defining a first outer end and a second outer end on opposite sides, an inner block defining a first inner end and a second inner end on opposite sides, and a pair of interconnect members, where each respective interconnect member of the pair of interconnect members connects the second outer end to the first inner end. The respective first ends of the pair of elongated tines being connected to the second inner end and the pad connector connects the mounting pad to the first outer end.
FILED Monday, August 27, 2018
APPL NO 16/113949
ART UNIT 2861 — Printing/Measuring and Testing
CURRENT CPC
Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement
G01P 15/097 (20130101) Original (OR) Class

Impedance Networks, e.g Resonant Circuits; Resonators
H03H 9/02259 (20130101)
H03H 9/02433 (20130101)
H03H 9/2473 (20130101)
H03H 2009/0248 (20130101)
H03H 2009/02291 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119116 Fertig et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Space Command (AFSPC)
Space Systems Command (SSC)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Space and Naval Warfare Systems (SPAWAR)
APPLICANT(S) Honeywell International Inc. (Morris Plains, New Jersey)
ASSIGNEE(S) Honeywell International Inc. (Charlotte, North Carolina)
INVENTOR(S) Chad Fertig (Bloomington, Minnesota);  Arthur Savchenko (Kirkland, Washington);  Joshua Dorr (Minneapolis, Minnesota);  Neil Krueger (Saint Paul, Minnesota);  Steven Tin (Plymouth, Minnesota)
ABSTRACT This disclosure is related to devices, systems, and techniques for determining, using an electro-opto-mechanical accelerometer system, a frequency value in order to determine an acceleration value. For example, an accelerometer system includes a light-emitting device configured to emit an optical signal and a circuit. The circuit is configured to modulate, using a modulating device, the optical signal to produce a modulated optical signal, receive, using a photoreceiver, the modulated optical signal, convert, using the photoreceiver, the modulated optical signal into an electrical signal, process the electrical signal to obtain a processed electrical signal, and transmit the processed electrical signal to the modulating device, where the modulating device is configured to modulate the optical signal based on the processed electrical signal. Additionally, the circuit is configured to determine, based on the processed electrical signal, a frequency value.
FILED Monday, April 01, 2019
APPL NO 16/371762
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement
G01P 15/097 (20130101) Original (OR) Class
G01P 15/0802 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119193 Cossairt et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) Northwestern University (Evanston, Illinois);  Southern Methodist University (Dallas, Texas)
ASSIGNEE(S) Northwestern University (Evanston, Illinois);  Southern Methodist University (Dallas, Texas)
INVENTOR(S) Oliver Strider Cossairt (Evanston, Illinois);  Fengqiang Li (Evanston, Illinois);  Florian Willomitzer (Evanston, Illinois);  Prasanna V. Rangarajan (Dallas, Texas)
ABSTRACT A system configured to generate images includes one or more narrowband electromagnetic sources configured to emit a first radiation and a second radiation. The system also includes a detector configured to detect first reflected radiation off of an object and second reflected radiation off of the object, where the first reflected radiation results from the first radiation and the second reflected radiation results from the second radiation. The system further includes a processor operatively coupled to the detector and configured to generate an image of the object based at least in part on a first amplitude of the first reflected radiation and a second amplitude of the second reflected radiation. The processor is also configured to determine a depth profile of the object based at least in part on the first reflected radiation and the second reflected radiation detected by the detector.
FILED Thursday, March 28, 2019
APPL NO 16/367532
ART UNIT 2886 — Optics
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 11/2441 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/4815 (20130101) Original (OR) Class
G01S 17/86 (20200101)
G01S 17/89 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119249 Ulmer et al.
FUNDED BY
Department of Defense (DOD)
United States Special Operations Command (SOCOM)
U.S. Special Operations Command (USSOCOM)
APPLICANT(S) Intellisense Systems, Inc. (Torrance, California)
ASSIGNEE(S) INTELLISENSE SYSTEMS, INC. (Torrance, California)
INVENTOR(S) Christopher Ulmer (San Pedro, California);  Dmitry Starodubov (Reseda, California);  Gregory Peng (Redondo Beach, California);  Rodion Tikhoplav (Santa Monica, California);  David Miller (San Pedro, California);  Andrew Kostrzewski (Garden Grove, California);  Koyiro Minakata (Irvine, California);  Gabriel Kaplan (Calabasas, California);  Tomasz Jannson (Torrance, California);  Edward Patton (Torrance, California);  Sookwang Ro (Glendale, California);  Ihor Berezhnyy (La Jolla, California)
ABSTRACT A portable weather station, including an lower body portion; an upper body portion disposed on the lower body portion in a spaced apart relationship thereby forming an open channel between the upper body portion and the lower body portion; and a plurality of weather condition sensors wherein a first set of one or more of the plurality of weather condition sensors is mounted on the upper body portion of the portable weather station and a second set of one or more of the plurality of weather condition sensors is mounted on the lower body portion of the portable weather station.
FILED Wednesday, May 29, 2019
APPL NO 16/425412
ART UNIT 2687 — Dynamic Storage Systems; Mechanical parts of Disk Drives
CURRENT CPC
Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 1/08 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/003 (20130101)
G01S 7/4813 (20130101)
G01S 17/86 (20200101)
G01S 17/95 (20130101)

Meteorology
G01W 1/02 (20130101) Original (OR) Class
G01W 1/08 (20130101)

Signalling or Calling Systems; Order Telegraphs; Alarm Systems
G08B 17/005 (20130101)
G08B 21/10 (20130101)
G08B 21/18 (20130101)

Technologies for Adaptation to Climate Change
Y02A 90/10 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119255 She et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S) Alan Jenting She (Somerville, Massachusetts);  Shuyan Zhang (Somerville, Massachusetts);  Federico Capasso (Cambridge, Massachusetts)
ABSTRACT A method of generating a layout data file for a metasurface device is disclosed. At a radial position of a metasurface device, the method determines a primitive cell of a first level having a metasurface feature pattern that is repeated around an arc corresponding to a circumference at the radial position. The method generates metasurface structures of higher levels. Each metasurface structure of a higher level includes multiple references to a structure or a primitive cell of a next lower level. The method stores at least a portion of a layout of the metasurface device to a layout data file. The layout includes references to metasurface structures of two or more of the higher levels.
FILED Thursday, July 19, 2018
APPL NO 16/040363
ART UNIT 2129 — AI & Simulation/Modeling
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 1/002 (20130101)
G02B 5/0268 (20130101) Original (OR) Class
G02B 27/0012 (20130101)

Electric Digital Data Processing
G06F 30/17 (20200101)
G06F 2119/18 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119256 Fuller
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) THE AEROSPACE CORPORATION (El Segundo, California)
ASSIGNEE(S) THE AEROSPACE CORPORATION (El Segundo, California)
INVENTOR(S) Jerome K. Fuller (Van Nuys, California)
ABSTRACT Many in the space weather community consider our understanding of the buoyancy of the thermosphere and its effects on the orbits of satellites in Low Earth Orbit (LEO) to be insufficient during short time frames. Disclosed herein is an approach for making on-demand thermosphere buoyancy measurements using a deployable low mass retroreflector with CubeSat-like dimensions. A CubeSat storing many retroreflectors can dispense one or more of these passive satellites according to a predetermined schedule or on-command, in response to an observed space weather phenomenon like a coronal mass ejection. With measurements of the orbit decay from these passive satellites, a better understanding of the relationship between space weather and orbital decay can be established with relatively low cost.
FILED Wednesday, April 03, 2019
APPL NO 16/374340
ART UNIT 2872 — Optics
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 11/25 (20130101)

Optical Elements, Systems, or Apparatus
G02B 5/13 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119257 Tabirian et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army
U.S. Army Natick Soldier Research, Development and Engineering Center (NSRDEC)
Secretary of the Army (SECARMY)
APPLICANT(S) Beam Engineering for Advanced Measurements Co. (Orlando, Florida);  U.S. Government as Represented by the Secretary of the Army (Natick, Massachusetts)
ASSIGNEE(S) Beam Engineering for Advanced Measurements Co (Orlando, Florida);  U.S. Government as Represented by the Secretary of the Army (Natick, Massachusetts)
INVENTOR(S) Nelson V. Tabirian (Winter Park, Florida);  Svetlana Serak (Oviedo, Florida);  David E. Roberts (Apopka, Florida);  Diane Steeves (Franklin, Massachusetts);  Brian Kimball (Shrewsbury, Massachusetts)
ABSTRACT Methods of fabricating optical lenses and mirrors, systems and composite structures based on diffractive waveplates, and fields of application of said lenses and mirrors that include imaging systems, astronomy, displays, polarizers, optical communication and other areas of laser and photonics technology. Diffractive lenses and mirrors of shorter focal length and larger size, with more closely spaced grating lines, and with more exacting tolerances on the optical characteristics, can be fabricated than could be fabricated by previous methods.
FILED Friday, December 07, 2018
APPL NO 16/213467
ART UNIT 1715 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Producing Particular Articles From Plastics or From Substances in a Plastic State
B29D 11/00269 (20130101)
B29D 11/00355 (20130101)
B29D 11/00432 (20130101)
B29D 11/00769 (20130101)

Optical Elements, Systems, or Apparatus
G02B 5/1857 (20130101)
G02B 5/1866 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119466 Michopoulos et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Secretary of the Navy (SECNAV)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) John Michopoulos (Washington, District of Columbia);  Athanasios Iliopoulos (Chevy Chase, Maryland);  John Steuben (Oxon Hill, Maryland)
ABSTRACT A method for flexible functionally tailorable slicing for additive manufacturing includes the steps of receiving and parsing an input model of an object to be additively manufactured; reconstructing a domain boundary of the object; computing individual layer boundaries of the object; constructing, for each layer, layer domains from respective enclosing boundaries; computing, for each layer, a perimeter shell and a volumetric infill by finding level sets of a field function selected by a user; collecting and arranging into a coherent sequence each perimeter shell and volumetric infill; and formatting the coherent sequence as motion commands for an additive manufacturing system.
FILED Friday, December 01, 2017
APPL NO 15/829088
ART UNIT 2119 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 50/02 (20141201)

Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 19/4099 (20130101) Original (OR) Class
G05B 2219/35134 (20130101)
G05B 2219/49007 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11120112 Chen
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Secretary of the Navy (SECNAV)
APPLICANT(S) United States of America as Represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Liping Chen (Port Hueneme, California)
ABSTRACT A three-factor authentication system for restricting and securing user-access to a system. The authentication system that includes a vein-image-capturing device for capturing and processing wrist-vein images. The unique biometric data is one factor of a three-factor authentication system, along with unique device identification data and a user PIN, all three used to validate and provide secure access to a user. This system can be used to restrict and provide secure access to information systems, physical spaces, personal computer devices, and any other device or system requiring controlled user access.
FILED Friday, September 27, 2019
APPL NO 16/585285
ART UNIT 2434 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/32 (20130101) Original (OR) Class
G06F 21/33 (20130101)
G06F 21/36 (20130101)
G06F 21/40 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/0643 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11120319 Wang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
U.S. Army Picatinny Arsenal (PICA)
APPLICANT(S) Advanced Functional Fabrics of America (Cambridge, Massachusetts)
ASSIGNEE(S) Advanced Functional Fabrics of America, Inc. (Cambridge, Massachusetts)
INVENTOR(S) Tairan Wang (Chelmsford, Massachusetts);  Tosha Hays (Atlanta, Georgia);  Yoel Fink (Brookline, Massachusetts);  Alexander Stolyarov (Belmont, Massachusetts);  Mihai Ibanescu (Somerville, Massachusetts)
ABSTRACT An article is a selected one of a set of articles. Each article of the set includes a fabric and is associated with a unique identification code. The selected article has a pattern distributed over at least 10% of an exposed surface of the selected article. The pattern encodes the identification code associated with the selected article, wherein the pattern is configured to be read and decoded by a mobile computing device in a manner wherein the selected article is contextually recognizable. A two-dimensional plaid pattern may be used to carry the identification code, which can be decoded according to described methods.
FILED Friday, June 28, 2019
APPL NO 16/457075
ART UNIT 2887 — Optics
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 19/06028 (20130101)
G06K 19/06103 (20130101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 7/13 (20170101)
G06T 11/00 (20130101)
G06T 2207/20021 (20130101)
G06T 2207/30204 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11120561 Andreopoulos et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Research Laboratory (AFRL)
United States Air Force (USAF)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Alexander Andreopoulos (San Jose, California);  Arnon Amir (San Jose, California);  Tapan K. Nayak (San Jose, California)
ABSTRACT Detection, tracking and recognition on networks of digital neurosynaptic cores are provided. In various embodiments, an image sensor is configured to provide a time-series of frames. A first artificial neural network is operatively coupled to the image sensor and configured to detect a plurality of objects in the time-series of frames. A second artificial neural network is operatively coupled to the first artificial neural network and configured to classify objects detected by the first neural network and output a location and classification of said classified objects. The first and second artificial neural networks comprise one or more spike-based neurosynaptic cores.
FILED Wednesday, October 31, 2018
APPL NO 16/177011
ART UNIT 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/6267 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/049 (20130101)
G06N 3/0454 (20130101)
G06N 3/0481 (20130101)

Image Data Processing or Generation, in General
G06T 7/251 (20170101) Original (OR) Class
G06T 2207/10016 (20130101)
G06T 2207/20084 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11120583 Raj et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
United States Army (USA)
Department of the Navy (DON)
Naval Research Laboratory (NRL)
Secretary of the Navy (SECNAV)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Raghu G. Raj (Fairfax, Virginia);  John Mckay (State College, Pennsylvania);  Vishal Monga (State College, Pennsylvania)
ABSTRACT Systems and methods are provided for imaging that demonstrably outperform previous approaches (especially compressive sensing based approaches). Embodiments of the present disclosure provide and solve an imaging cost function via a stochastic approximation approach. By doing so, embodiments of the preset disclosure provide a significant means of generalization and flexibility to adapt to different application domains while being competitive in terms of computational complexity.
FILED Tuesday, October 29, 2019
APPL NO 16/667473
ART UNIT 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image Data Processing or Generation, in General
G06T 11/006 (20130101) Original (OR) Class
G06T 2211/424 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11120856 Victora et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Randall H. Victora (New Brighton, Minnesota);  Roy C. Bell (Minneapolis, Minnesota)
ABSTRACT An example article includes a composite free layer and a conductive channel. The composite free layer includes a high-anisotropy ferromagnetic layer, a non-magnetic transition metal layer adjacent to the high-anisotropy ferromagnetic layer, and an ultra-low damping magnetic insulator. The non-magnetic transition metal layer is between the ultra-low damping magnetic insulator and the high-anisotropy ferromagnetic layer. An example spin-orbit torque (SOT) stack may include the example article. Techniques for forming and switching example articles and SOT stacks are described.
FILED Monday, April 22, 2019
APPL NO 16/390793
ART UNIT 2898 — Semiconductors/Memory
CURRENT CPC
Static Stores
G11C 11/161 (20130101) Original (OR) Class

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/222 (20130101)
H01L 43/08 (20130101)
H01L 43/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11120968 Hujsak et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Research Laboratory (AFRL)
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Karl A. Hujsak (Evanston, Illinois);  Vinayak P. Dravid (Glenview, Illinois)
ABSTRACT Aspects of the present disclosure involve applying a Multi-Objective Autonomous Dynamic Sampling algorithm in an electron or other radiation/charged-particle microscope for the characterization of elemental, chemical, and crystallographic information with over an order of magnitude improvement in time and exposure.
FILED Thursday, October 25, 2018
APPL NO 16/758326
ART UNIT 2881 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/2251 (20130101)
G01N 2223/402 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 37/28 (20130101) Original (OR) Class
H01J 2237/24485 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11121219 Dao et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  Nanyang Technological University (Singapore, Singapore)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  Nanyang Technological University (Singapore, Singapore)
INVENTOR(S) Ming Dao (West Roxbury, Massachusetts);  Ju Li (Weston, Massachusetts);  Zhe Shi (Cambridge, Massachusetts);  Subra Suresh (Wellesley, Massachusetts)
ABSTRACT Compositions and methods related to straining defect doped materials as well as their methods of use in electrical circuits are generally described.
FILED Friday, September 27, 2019
APPL NO 16/585308
ART UNIT 2895 — Semiconductors/Memory
CURRENT CPC
Microstructural Devices or Systems, e.g Micromechanical Devices
B81B 7/008 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/02664 (20130101)
H01L 29/1054 (20130101) Original (OR) Class
H01L 41/0536 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11121239 Petta et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army
Army Research Office (ARO)
National Security Agency (NSA)
APPLICANT(S) The Trustees of Princeton University (Princeton, New Jersey)
ASSIGNEE(S) The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S) Jason Petta (Princeton, New Jersey);  Xiao Mi (Princeton, New Jersey);  David Zajac (Gibsonia, Pennsylvania)
ABSTRACT Methods, devices, and systems are described for storing and transferring quantum information. An example device may comprise at least one semiconducting layer, one or more conducting layers configured to define at least two quantum states in the at least one semiconducting layer and confine an electron in or more of the at least two quantum states, and a magnetic field source configured to generate an inhomogeneous magnetic field. The inhomogeneous magnetic field may cause a first coupling of an electric charge state of the electron and a spin state of the electron. The device may comprise a resonator configured to confine a photon. An electric-dipole interaction may cause a second coupling of an electric charge state of the electron to an electric field of the photon.
FILED Wednesday, August 07, 2019
APPL NO 16/534431
ART UNIT 2826 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 29/66977 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11121305 Gong et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S) CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania);  University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Songbin Gong (Champaign, Illinois);  Gianluca Piazza (Pittsburgh, Pennsylvania)
ABSTRACT In one aspect, a microelectronic device comprises: a suspended lithium-based thin film; and one or more electrodes disposed on the suspended lithium-based thin film, wherein the one or more electrodes comprises one or more fingers, and a width of at least one outer finger of the one or more fingers is smaller than a width of at least one inner finger of the one or more fingers.
FILED Thursday, December 28, 2017
APPL NO 15/857323
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 41/047 (20130101) Original (OR) Class
H01L 41/313 (20130101)
H01L 41/332 (20130101)
H01L 41/0477 (20130101)
H01L 41/1873 (20130101)

Impedance Networks, e.g Resonant Circuits; Resonators
H03H 3/02 (20130101)
H03H 9/13 (20130101)
H03H 9/02228 (20130101)
H03H 9/02559 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11121336 Forrest et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Energy (DOE)
Office of Science (DOEOS)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Stephen R. Forrest (Ann Arbor, Michigan);  Jeramy D. Zimmerman (San Francisco, California);  Xin Xiao (Ann Arbor, Michigan)
ABSTRACT Disclosed herein are organic photosensitive optoelectronic devices comprising two electrodes in superposed relation; a mixed photoactive layer located between the two electrodes, wherein the mixed photoactive layer comprises at least one donor material having a HOMO energy and at least one acceptor material having a LUMO energy, wherein the at least one donor material and the at least one acceptor material form a mixed donor-acceptor heterojunction; a photoactive layer adjacent to and interfacing with the mixed photoactive layer, wherein the photoactive layer comprises a material having a LUMO energy within 0.3 eV of the LUMO energy of the at least one acceptor material or a HOMO energy within 0.3 eV of the HOMO energy of the at least one donor material; and a buffer layer adjacent to and interfacing with the mixed photoactive layer.
FILED Friday, November 22, 2013
APPL NO 14/646154
ART UNIT 2829 — Semiconductors/Memory
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 10/00 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 51/0046 (20130101)
H01L 51/0056 (20130101)
H01L 51/0072 (20130101)
H01L 51/4253 (20130101) Original (OR) Class
H01L 2251/552 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/549 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11121385 Wynne et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Teledyne Energy Systems, Inc. (Thousand Oaks, California)
ASSIGNEE(S) TELEDYNE ENERGY SYSTEMS, INC. (Thousand Oaks, California)
INVENTOR(S) Robert K. Wynne (New Freedom, Pennsylvania);  Patrick Scott Ferguson (Baltimore, Maryland);  Robert Christopher Utz (Phoenix, Maryland)
ABSTRACT A fuel cell purge system includes a primary fuel cell in fluid communication with a purge cell. Fuel and oxidant purged with inert gas impurities from the primary fuel cell react in the purge cell, thereby decreasing the volume of purged gases and facilitating storage while maintaining fuel cell electrochemical performance.
FILED Monday, November 18, 2019
APPL NO 16/686275
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 8/0662 (20130101)
H01M 8/04179 (20130101)
H01M 8/04231 (20130101) Original (OR) Class
H01M 8/04291 (20130101)
H01M 2008/1095 (20130101)
H01M 2250/20 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 90/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11121473 Chapman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
U.S. Air Force
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Adam J. Chapman (Medford, Massachusetts);  Alan J. Fenn (Wayland, Massachusetts);  Pierre Dufilie (Marlborough, Massachusetts)
ABSTRACT A compact shallow cavity-backed discone antenna array for conformal omnidirectional antenna applications is disclosed. The antenna array comprises a plurality of discone antennas arranged in a ring array within a circular contoured conical cavity. The cavity is covered with an electrically transparent radome. The individual discone antenna elements are fed with coaxial transmission lines. Good performance is demonstrated by simulation and by experiment in terms of reflection coefficient and omnidirectional gain radiation patterns from about 960 MHz to 1220 MHz. In one embodiment, the shallow cavity-backed discone antenna array may be used as a flush-mounted antenna that conforms to the outer mold line of an aircraft.
FILED Thursday, April 16, 2020
APPL NO 16/850372
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 1/286 (20130101)
H01Q 1/421 (20130101)
H01Q 9/28 (20130101)
H01Q 13/18 (20130101)
H01Q 21/0056 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11121523 Deppe
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Research Laboratory (ARL)
Army Research Office (ARO)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida)
ASSIGNEE(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida)
INVENTOR(S) Dennis G. Deppe (Oviedo, Florida)
ABSTRACT A semiconductor heterostructure device includes a middle layer including an inner conducting channel and an outer current blocking region. A depleted heterojunction current blocking region (DHCBR) is within the outer current blocking region. The DHCBR includes a first depleting impurity specie including a Column II acceptor, and a second depleting impurity comprising oxygen which increases a depletion of the DHCBR so that the DHCBR forces current to flow into the conducting channel during electrical biasing under normal operation of the semiconductor heterostructure device.
FILED Tuesday, October 08, 2019
APPL NO 16/595560
ART UNIT 2817 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/046 (20130101)
H01L 29/165 (20130101)
H01L 29/0619 (20130101)
H01L 29/1608 (20130101)
H01L 29/7395 (20130101)
H01L 29/7828 (20130101)
H01L 29/8083 (20130101)
H01L 33/145 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 5/2063 (20130101)
H01S 5/18308 (20130101) Original (OR) Class
H01S 5/18358 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11121557 Cottrell et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Aurora Flight Sciences Corporation (Manassas, Virginia)
ASSIGNEE(S) Aurora Flight Sciences Corporation (Manassas, Virginia)
INVENTOR(S) Daniel Cottrell (Manassas, Virginia);  Garrett Hennig (Manassas, Virginia);  Christopher Hermann (Manassas, Virginia)
ABSTRACT A power distribution system is disclosed for conducting electrical power through a combination of hollow tube conductors and flexible cabling. Each hollow tube conductor includes an end formed into flat pads. The flexible cabling comprises litz wire, and includes ends crimped to integral lugs. An end of the flexible cabling is coupled to an end of the hollow tube conductor. The other end of the flexible cabling is coupled to an electric device. The other end of the hollow tube conductor is coupled to another flexible cable, which is in turn coupled to another electric device. By connecting the hollow tube conductors, flexible cabling, and electrical devices in this way, an electrically conductive pathway may be established between the electrical devices. The power distribution system conducts alternating current (AC) power, and addresses the skin effect phenomenon that occurs when conducting AC power. The power distribution system can be utilized in the highly-constrained environment of electric aircraft, where weight and space is at a premium.
FILED Friday, April 06, 2018
APPL NO 15/946947
ART UNIT 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles
B60L 2230/12 (20130101)

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 31/14 (20130101)
B64D 33/00 (20130101)
B64D 41/00 (20130101)
B64D 2221/00 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 9/003 (20130101)

Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors
H01R 4/70 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 3/46 (20130101) Original (OR) Class
H02J 4/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11122026 Koved et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Air Force Research Laboratory (AFRL)
U.S. Air Force
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Lawrence Koved (Pleasantville, New York);  Bo Zhang (Hoboken, New Jersey)
ABSTRACT Adjustments to be made to a system for authenticating users may be made by performing the following operations: obtaining a stochastic model of the system, wherein the stochastic model includes two or more classes of requests; obtaining a set of preferences for handling authentication requests and a set of operational parameter values; determining, based at least in part on the stochastic model and the set of operational parameter values, that adjusting an authentication scheme will improve a probable degree to which the authentication system will meet the set of preferences; responsive to the determination that adjusting the authentication scheme will improve the probable degree to which the system for authenticating users will meet the set of preferences, adjusting the authentication scheme of the system for authenticating users; and performing an authentication of a user based on the adjusted authentication scheme.
FILED Thursday, August 01, 2019
APPL NO 16/528720
ART UNIT 2436 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/32 (20130101)
H04L 63/08 (20130101) Original (OR) Class
H04L 63/20 (20130101)
H04L 63/105 (20130101)

Wireless Communication Networks
H04W 12/06 (20130101)
H04W 12/065 (20210101)
H04W 12/068 (20210101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11122664 Irizarry
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Surface Warfare Center (NSWC)
Secretary of the Navy (SECNAV)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Crane, Indiana)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) George L Irizarry (Bloomington, Indiana)
ABSTRACT Exemplary embodiments are directed towards safety systems associated with ultra-fast fault signal pulses to increase the fault signal pulses from milliseconds to seconds to energize external devices (e.g., LED lights). This is turn will alert the operators that the system is operational or a fault was detected. The fault signal width pulses are extended to drive or trigger external devices, such as external relays, which in turn completes a circuit to energize any external devices.
FILED Thursday, September 24, 2020
APPL NO 17/031011
ART UNIT 2896 — Cryptography and Security
CURRENT CPC
Electric Heating; Electric Lighting Not Otherwise Provided for
H05B 45/32 (20200101)
H05B 45/37 (20200101)
H05B 45/50 (20200101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US D930788 Roth
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Secretary of the Army (SECARMY)
APPLICANT(S) The United State of America as represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Marc L. Roth (Owens Cross Roads, Alabama)
ABSTRACT
FILED Thursday, April 23, 2020
APPL NO 29/732318
ART UNIT 2925 — Design
CURRENT CPC
Environmental heating and cooling; fluid handling and sanitary equipment
D23/209
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 11116154 Shakoor et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) DONALD DANFORTH PLANT SCIENCE CENTER (St. Louis, Missouri)
ASSIGNEE(S) Donald Danforth Plant Science Center (St. Louis, Missouri)
INVENTOR(S) Nadia Shakoor (St. Louis, Missouri);  Todd Mockler (St. Louis, Missouri);  William Francis Kezele (St. Louis, Missouri)
ABSTRACT A field controller and sensor is presented as an elongate body having a hollow interior and axially opposite first and second ends with a first arm extending outward from the elongate body adjacent to the first axial end and a second arm extending outward from the elongate body adjacent to the second, axially opposite end. Each of the arms has an imaging device. The first arm imaging device is positioned to obtain images in a direction toward the second axial end of the elongate body. The second arm imaging device is positioned to obtain images in a direction toward the first axial end. The first and second arms are spaced apart from one another along a length of the elongate body at a distance sufficient to image a canopy of crop growth in a field in which the field controller and sensor is deployed. The sensor may be formed from modules that allow the operator the ability to vary the height of the sensor by stacking the modules together end to end, which in turn allows users to scale their particular system with varying crop sizes within crop rotations.
FILED Friday, September 08, 2017
APPL NO 16/328565
ART UNIT 2116 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Planting; Sowing; Fertilising
A01C 23/007 (20130101)

Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering
A01G 25/167 (20130101) Original (OR) Class

Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 19/042 (20130101)
G05B 2219/2625 (20130101)

Pictorial Communication, e.g Television
H04N 5/247 (20130101)
H04N 5/2253 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116244 Lee
FUNDED BY
Department of Energy (DOE)
Lawrence Livermore National Laboratory (LLNL)
Lawrence Livermore National Security LLC (LLNS)
APPLICANT(S) U.S. Department of Energy (Washington, District of Columbia)
ASSIGNEE(S) U.S. Department of Energy (Washington, District of Columbia)
INVENTOR(S) Henry Yu-Heng Lee (San Jose, California)
ABSTRACT The present invention comprises a precision cooking oven that utilizes laser sheets to cook food, thus creating homogeneously heated and uniformly seared food bodies and surfaces. Laser sheets move back and forth evenly injecting heat into items being cooked. All food cold or hot areas can be eliminated since intersecting laser lines can be completely projected on and accommodate an item's exterior surfaces. Items with non-uniform cross-sections and properties can be cooked uniformly by controlling the exact amount of energy projected into differing sections of the food. The oven is also capable of cooking autonomously. Since laser sheets can be precisely controlled, cooking results can be very predictable once the boundary conditions for a thermal analysis are determined. The oven can detect the properties of the items to be cooked and thereafter compute the needed time and power to achieve the desired results stipulated by an oven operator.
FILED Wednesday, January 16, 2019
APPL NO 16/249068
ART UNIT 3761 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Bakers\' Ovens; Machines or Equipment for Baking
A21B 1/02 (20130101)

Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General
A23L 5/10 (20160801)
A23L 5/15 (20160801) Original (OR) Class
A23L 5/30 (20160801)
A23L 5/32 (20160801)

Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages
A23V 2002/00 (20130101)

Domestic Stoves or Ranges; Details of Domestic Stoves or Ranges, of General Application
F24C 1/00 (20130101)
F24C 7/00 (20130101)
F24C 7/046 (20130101)
F24C 7/087 (20130101)

Electric Heating; Electric Lighting Not Otherwise Provided for
H05B 6/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117091 Aines et al.
FUNDED BY
Department of Energy (DOE)
Lawrence Livermore National Laboratory (LLNL)
Lawrence Livermore National Security LLC (LLNS)
APPLICANT(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California);  The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California);  The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Roger D. Aines (Livermore, California);  Christopher M. Spadaccini (Oakland, California);  Joshuah K. Stolaroff (Oakland, California);  William L. Bourcier (Livermore, California);  Jennifer A. Lewis (Cambridge, Massachusetts);  Eric B. Duoss (Dublin, California);  John J. Vericella (Oakland, California)
ABSTRACT Method and apparatus for separating a target substance from a fluid or mixture. Capsules having a coating and stripping solvents encapsulated in the capsules are provided. The coating is permeable to the target substance. The capsules having a coating and stripping solvents encapsulated in the capsules are exposed to the fluid or mixture. The target substance migrates through the coating and is taken up by the stripping solvents. The target substance is separated from the fluid or mixture by driving off the target substance from the capsules.
FILED Monday, July 16, 2018
APPL NO 16/036411
ART UNIT 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 53/229 (20130101)
B01D 53/1425 (20130101)
B01D 53/1456 (20130101)
B01D 53/1468 (20130101)
B01D 53/1475 (20130101) Original (OR) Class
B01D 53/1481 (20130101)
B01D 2252/102 (20130101)
B01D 2252/602 (20130101)
B01D 2252/20421 (20130101)
B01D 2252/20426 (20130101)
B01D 2252/20431 (20130101)
B01D 2252/20484 (20130101)
B01D 2258/0283 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/324 (20130101)
B01J 20/327 (20130101)
B01J 20/3244 (20130101)
B01J 20/3295 (20130101)

Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG]
Y02C 20/10 (20130101)
Y02C 20/40 (20200801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117092 Li et al.
FUNDED BY
Department of Energy (DOE)
National Energy Technology Laboratory (NETL)
APPLICANT(S) GAS TECHNOLOGY INSTITUTE (Des Plaines, Illinois)
ASSIGNEE(S) GAS TECHNOLOGY INSTITUTE (Des Plaines, Illinois)
INVENTOR(S) Shiguang Li (Mount Prospect, Illinois);  Travis Pyrzynski (Elgin, Illinois)
ABSTRACT Processes and systems for the energy efficient capture of CO2 from a flue gas stream such as produced or resulting from power plant operation, are provided. The processes and systems integrate the use of high CO2/N2 selectivity membranes and high CO2 flux membranes, to capture CO2. Useful membranes can desirably be graphene oxide-based membranes.
FILED Thursday, March 14, 2019
APPL NO 16/353061
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 53/226 (20130101) Original (OR) Class
B01D 53/265 (20130101)
B01D 71/024 (20130101)
B01D 2053/221 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/50 (20170801)
C01B 2210/0012 (20130101)
C01B 2210/0046 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117121 Paranthaman et al.
FUNDED BY
Department of Energy (DOE)
UT-Battelle, LLC (UT-BATTELLE)
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee);  Georgia Institute of Technology (Atlanta, Georgia);  Wake Forest University (Winston-Salem, North Carolina)
ASSIGNEE(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Mariappan Paranthaman (Knoxville, Tennessee);  Amit K. Naskar (Knoxville, Tennessee);  Abdou Lachgar (Winston-Salem, North Carolina);  Younan Xia (Atlanta, Georgia);  Zachary David Hood (Atlanta, Georgia);  Shiba Prasad Adhikari (Winston-Salem, North Carolina)
ABSTRACT The invention provides a catalyst and a method for making the catalyst. The catalyst comprises a porous carbon composite impregnated with a salt. The catalyst comprises a porous carbon composite impregnated with a salt.
FILED Monday, June 25, 2018
APPL NO 16/016704
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 27/053 (20130101) Original (OR) Class
B01J 35/002 (20130101)
B01J 35/109 (20130101)
B01J 35/1009 (20130101)
B01J 35/1028 (20130101)
B01J 35/1038 (20130101)
B01J 35/1061 (20130101)
B01J 37/084 (20130101)
B01J 37/0207 (20130101)
B01J 37/343 (20130101)
B01J 2523/62 (20130101)
B01J 2523/842 (20130101)

Destructive Distillation of Carbonageous Materials for Production of Gas, Coke, Tar, or Similar Materials
C10B 53/07 (20130101)

Fatty Acids From Fats, Oils or Waxes; Candles; Fats, Oils or Fatty Acids by Chemical Modification of Fats, Oils, or Fatty Acids Obtained Therefrom
C11C 3/00 (20130101)
C11C 3/003 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117217 Robinson
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
National Technology and Engineering Solutions of Sandia, LLC (NTESS)
Sandia National Laboratories (SNL)
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) David Robinson (Hayward, California)
ABSTRACT A metal film for use by an additive manufacturing apparatus is described herein. The metal film has a support structure and metal voxels removably attached to the support structure by respective junctions. When a metal voxel in the metal film is impacted by an energy pulse from an energy source of the additive manufacturing apparatus, one or more junctions that attach the metal voxel to the support structure are broken, resulting in the metal voxel detaching from the metal film (at a desired location in a two-dimensional plane).
FILED Thursday, August 31, 2017
APPL NO 15/693040
ART UNIT 1784 — Miscellaneous Articles, Stock Material
CURRENT CPC
Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 26/342 (20151001) Original (OR) Class
B23K 2103/16 (20180801)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 5/22 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 70/00 (20141201)

Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25
C23F 1/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117361 Hensleigh et al.
FUNDED BY
Department of Energy (DOE)
Lawrence Livermore National Laboratory (LLNL)
Lawrence Livermore National Security LLC (LLNS)
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Ryan Hensleigh (Colstrip, Montana);  Eric B. Duoss (Danville, California)
ABSTRACT The present disclosure relates to a method for performing a three dimensional (3D) printing process. A primary light beam having a wavelength sufficient to initiate polymerization of a photoresin is generated and patterned into a patterned primary beam. The patterned primary beam is directed toward an ultraviolet (UV) or visible light sensitive photoresin to initiate polymerization of select areas of the photoresin. The photoresin is also illuminated with a secondary light beam having a wavelength of at least one of about 765 nm, 1064 nm, or 1273 nm. The secondary light beam stimulates triplet oxygen into singlet oxygen, which controls oxygen inhibition in additional areas bordering the select areas, to enable controlled polymerization inhibition in the additional areas bordering the select areas.
FILED Thursday, April 09, 2020
APPL NO 16/844669
ART UNIT 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/20 (20170801)
B29C 64/124 (20170801)
B29C 64/135 (20170801)
B29C 64/227 (20170801)
B29C 64/264 (20170801)
B29C 64/386 (20170801)
B29C 64/393 (20170801)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
B33Y 50/02 (20141201) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117567 Huang et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Toyota Motor Engineering and Manufacturing North America, Inc. (Plano, Texas);  The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S) Toyota Motor Engineering and Manufacturing North America, Inc. (Plano, Texas);  The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Mike X. Huang (Ann Arbor, Michigan);  Yushi Shibaike (Canton, Michigan);  Shengqi Zhang (Houston, Texas);  Di Chen (Ann Arbor, Michigan);  Anna G Stefanopoulou (Ann Arbor, Michigan)
ABSTRACT The disclosure is directed to solving a full trajectory optimization problem in real-time for a hybrid electric vehicle (HEV) such that future driving conditions and energy usage may be fully considered in determining optimal engine energy usage and battery energy usage in real-time during a trip. An electronic control unit of the HEV may be configured to: receive route information for a route to be driven by the HEV; and after receiving the route information, iterating the operations of: measuring a current state of charge (SOC) of the battery; using at least the measured SOC and an initial co-state value stored in a memory, performing a process to iteratively update the co-state value to obtain an updated co-state value; using at least the updated co-state value, computing an updated control value; and applying the updated control value to control a usage of the battery and the internal combustion engine.
FILED Tuesday, June 26, 2018
APPL NO 16/019512
ART UNIT 3665 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit
B60W 20/11 (20160101)
B60W 20/12 (20160101) Original (OR) Class
B60W 50/0097 (20130101)
B60W 2510/244 (20130101)
B60W 2710/087 (20130101)

Systems for Controlling or Regulating Non-electric Variables
G05D 1/0217 (20130101)
G05D 2201/0213 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117810 Klausner et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) James Klausner (Gainesville, Florida);  Kelvin Fnu Randhir (Gainesville, Florida);  Nicholas AuYueng (Corvallis, Oregon);  Like Li (Gainesville, Florida);  Nathan Rhodes (Gainesville, Florida);  Amey Anand Barde (Gainesville, Florida);  Renwei Mei (Gainesville, Florida);  David Worthington Hahn (Gainesville, Florida)
ABSTRACT Disclosed herein is a method comprising heating a strontium-containing compound using radiation in a first reactor; decomposing the strontium-containing compound into an oxide and carbon dioxide as a result of heat generated by the exposure to the radiation; reacting the oxide and the carbon dioxide in a second reactor; where the oxide and carbon dioxide react to produce heat; heating a working fluid using the heat produced in the second reactor; and driving a turbine with the heated working fluid to generate energy. Disclosed herein too is a composition comprising strontium carbonate; and strontium zirconate; where the mass ratio of strontium carbonate to strontium zirconate 2:8 to 8:2.
FILED Wednesday, March 06, 2019
APPL NO 16/294152
ART UNIT 1796 — Miscellaneous Articles, Stock Material
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 15/04 (20130101)
C01B 32/50 (20170801)

Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals
C01F 11/06 (20130101) Original (OR) Class
C01F 11/187 (20130101)

Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for
F03G 6/003 (20130101)
F03G 6/06 (20130101)

Details of Heat-exchange and Heat-transfer Apparatus, of General Application
F28F 13/18 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/46 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 20/129 (20151101)
Y02P 20/133 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118160 Wan et al.
FUNDED BY
Department of Energy (DOE)
Lawrence Berkeley National Laboratory (LBNL)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Kenneth H. Wan (El Cerrito, California);  James B. Brown (El Sobrante, California);  Susan E. Celniker (Lafayette, California)
ABSTRACT The present invention provides for a probiotic composition for enhancing a subject's, such as an insect's, resistance to a pesticide comprising: (a) a microorganism capable of expressing one or more enzymes for metabolizing the pesticide, and (b) at least one feed ingredient for a subject. The present invention also provides for a method for enhancing a subject's, such as an insect's, resistance to a pesticide comprising administering to a subject the probiotic composition.
FILED Wednesday, November 07, 2018
APPL NO 16/183529
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 53/00 (20130101)
A01K 2227/706 (20130101)

Fodder
A23K 10/18 (20160501)
A23K 10/33 (20160501)
A23K 20/163 (20160501)
A23K 50/90 (20160501)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0056 (20130101)
A61K 35/741 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 1/14 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/205 (20210501) Original (OR) Class

Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms
C12R 2001/02 (20210501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118197 Xu et al.
FUNDED BY
Department of Energy (DOE)
Lawrence Berkeley National Laboratory (LBNL)
National Nuclear Security Administration (NNSA)
National Technology and Engineering Solutions of Sandia, LLC (NTESS)
APPLICANT(S) NATIONAL TECHNOLOGY and ENGINEERING SOLUTIONS OF SANDIA, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Feng Xu (Albany, California);  Blake Simmons (San Francisco, California);  Seema Singh (Clarksburg, Maryland)
ABSTRACT In one aspect, the present invention provides methods for preparing a fermentation product. The methods include pre-treating a mixture of biomass and ionic liquid, wherein the ionic liquid comprises a choline cation and the biomass comprises polysaccharide and lignin. The methods further include forming hydrolysates from the introduction of glycoside hydrolase to the pre-treated mixture at conditions sufficient to produce a sugar composition mixture for fermentation steps. The present invention provides methods for loading biomass mixtures in a batch-fed process, wherein the biomass slurries can be loaded into water or a concentrated sugar composition for hydrolysate production. The methods can be performed in a one-pot process, wherein the ionic liquids are present in the mixtures throughout each step. Aspects of the invention provide compositions of sugar composition mixtures and fermentation product mixtures.
FILED Monday, November 21, 2016
APPL NO 15/777649
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/10 (20130101) Original (OR) Class
C12P 19/02 (20130101)
C12P 19/14 (20130101)
C12P 2201/00 (20130101)
C12P 2203/00 (20130101)

Saccharides Obtained From Natural Sources or by Hydrolysis of Naturally Occurring Disaccharides, Oligosaccharides or Polysaccharides
C13K 1/02 (20130101)
C13K 13/002 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 50/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118204 Liszka et al.
FUNDED BY
Department of Energy (DOE)
Lawrence Berkeley National Laboratory (LBNL)
National Nuclear Security Administration (NNSA)
National Technology and Engineering Solutions of Sandia, LLC (NTESS)
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Michael Liszka (Berkeley, California);  Kenneth Sale (Livermore, California);  Blake Simmons (San Francisco, California)
ABSTRACT In one aspect, the present invention provides a method for preparing a sugar composition. The method includes: forming a mixture including polysaccharide biomass and an ionic liquid solution, wherein the ionic liquid solution contains water and an ionic liquid, and wherein the ionic liquid contains a dicarboxylic acid anion and a cation. The pH of the mixture is greater than or equal to about 10, and the molar ratio of the dicarboxylic acid anion to the cation is at least about 1:2. The method further includes: maintaining the mixture under conditions sufficient to dissolve at least a portion of the polysaccharide present in the polysaccharide biomass; reducing the pH of the mixture containing the dissolved polysaccharide to at least about 7; adding at least one glycoside hydrolase to the mixture having the reduced pH.
FILED Friday, October 30, 2015
APPL NO 15/523355
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Derivatives of Natural Macromolecular Compounds
C08H 8/00 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 5/002 (20130101)
C12P 5/007 (20130101)
C12P 7/04 (20130101)
C12P 19/02 (20130101)
C12P 19/14 (20130101) Original (OR) Class
C12P 2201/00 (20130101)

Saccharides Obtained From Natural Sources or by Hydrolysis of Naturally Occurring Disaccharides, Oligosaccharides or Polysaccharides
C13K 1/02 (20130101)
C13K 13/002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118247 Gong et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOEOS)
APPLICANT(S) QUESTEK INNOVATIONS LLC (Evanston, Illinois)
ASSIGNEE(S) QUESTEK INNOVATIONS LLC (Evanston, Illinois)
INVENTOR(S) Jiadong Gong (Evanston, Illinois);  David R. Snyder (Des Plaines, Illinois);  Jason T. Sebastian (Chicago, Illinois)
ABSTRACT Alloys, processes for preparing the alloys, and articles including the alloys are provided. The alloys can include, by weight, about 4% to about 7% aluminum, 0% to about 0.2% carbon, about 7% to about 11% cobalt, about 5% to about 9% chromium, about 0.01% to about 0.2% hafnium, about 0.5% to about 2% molybdenum, 0% to about 1.5% rhenium, about 8% to about 10.5% tantalum, about 0.01% to about 0.5% titanium, and about 6% to about 10% tungsten, the balance essentially nickel and incidental elements and impurities.
FILED Wednesday, March 13, 2019
APPL NO 16/352136
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Casting of Metals; Casting of Other Substances by the Same Processes or Devices
B22D 21/005 (20130101)
B22D 25/02 (20130101)

Alloys
C22C 1/023 (20130101)
C22C 19/05 (20130101)
C22C 19/057 (20130101) Original (OR) Class

Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys
C22F 1/10 (20130101)

Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/28 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/323 (20130101)
F05D 2230/21 (20130101)
F05D 2300/17 (20130101)
F05D 2300/607 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118249 Burtch
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
National Technology and Engineering Solutions of Sandia, LLC (NTESS)
Sandia National Laboratories (SNL)
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Nicholas C. Burtch (Oakland, California)
ABSTRACT A feedstock material for use in an additive manufacturing apparatus is prepared from a first material and a metal organic framework (MOF). The MOF comprises a plurality of nodes and a plurality of linkers, the plurality of linkers coupled to the plurality of nodes, thereby forming a framework. The MOF has a lower coefficient of thermal expansion than a coefficient of thermal expansion for the first material. As a result, the feedstock material has a reduced coefficient of thermal expansion as compared to the first material alone and thus exhibits low thermal expansion as its temperature is increased. The coefficient of thermal expansion for the MOF may be modified by using a different plurality of nodes and/or a different plurality of linkers, as well as by incorporating guest molecules or atoms into the framework of the MOF.
FILED Wednesday, September 27, 2017
APPL NO 15/717265
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 10/00 (20210101)

Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster
B28B 1/001 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/10 (20170801)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 70/00 (20141201)
B33Y 70/10 (20200101)

Alloys
C22C 1/05 (20130101)
C22C 32/0094 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118964 Williams
FUNDED BY
Department of Energy (DOE)
UT-Battelle, LLC (UT-BATTELLE)
Oak Ridge National Laboratory (ORNL)
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Brian P. Williams (Oak Ridge, Tennessee)
ABSTRACT A system and method with AC coupling that reserves photodiode bandwidth in a biased configuration, allows optimal transimpedance amplifier performance, retains DC signal measurement capability, and does not introduce noise into the balanced detection signal.
FILED Thursday, August 20, 2020
APPL NO 16/998678
ART UNIT 2878 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 1/18 (20130101) Original (OR) Class
G01J 1/4228 (20130101)
G01J 2001/186 (20130101)
G01J 2001/444 (20130101)
G01J 2001/446 (20130101)

Electric Digital Data Processing
G06F 7/588 (20130101)

Electric Heating; Electric Lighting Not Otherwise Provided for
H05B 47/11 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119069 Ibrahim et al.
FUNDED BY
Department of Energy (DOE)
Battelle Memorial Institute (BATTELLE)
Pacific Northwest National Laboratory (PNNL)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S) BATTELLE MEMORIAL INSTITUTE (Richland, Washington)
INVENTOR(S) Yehia M. Ibrahim (West Richland, Washington);  Adam L. Hollerbach (Richland, Washington);  Ailin Li (Richland, Washington)
ABSTRACT An apparatus includes multiple levels of ion transport channels, with successive levels coupled by elevator channels. Efficient three dimensional packing provides long path lengths in practical volumes for ion mobility separation with high resolving power. Disclosed elevator configurations provide efficient routing of ion transport channels across levels with low ion loss, enabling ion mobility separation over 100 levels or more. Elevator configurations include (i) opposed traveling waves meeting at an elevator entrance, (ii) external elevator with a wrap-around electrode bank, (iii) external elevator with electrode banks on parallel extension plates, or (iv) elevator operating in surfing mode, in various combinations. Manufacture is aided by printed wiring boards, with interchangeable boards. Assembly with motherboard, spacer block(s), and alignment pins provides efficient distribution of electrode excitations and accurate reproducible positioning.
FILED Friday, October 25, 2019
APPL NO 16/664435
ART UNIT 2881 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/68 (20130101)
G01N 27/622 (20130101) Original (OR) Class

Electric Discharge Tubes or Discharge Lamps
H01J 49/061 (20130101)
H01J 49/062 (20130101)
H01J 49/4225 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119386 Pooser et al.
FUNDED BY
Department of Energy (DOE)
UT-Battelle, LLC (UT-BATTELLE)
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Raphael C. Pooser (Oak Ridge, Tennessee);  Benjamin J. Lawrie (Oak Ridge, Tennessee);  Petro Maksymovych (Oak Ridge, Tennessee)
ABSTRACT A truncated non-linear interferometer-based atomic force microscope (AFM) includes an input port and a non-linear amplifier that renders a probe beam and a conjugate beam. The AFM includes local oscillators having a relationship with the probe beam and the conjugate beam. The displacement of the AFM's cantilever is transduced by the probe beam, and/or the conjugate beam or their respective local oscillators. The AFM's phase-sensitive detectors detect a phase modulation between the respective local oscillators and the probe beam and the conjugate beam. The detected phase modulation corresponds to the change in phase. The AFM's circuitry measures phase signals that are indicative of the cantilever displacement. The resulting measurement signals exhibit a quantum noise reduction in either the intensity difference or phase sum quadrature.
FILED Wednesday, December 18, 2019
APPL NO 16/719437
ART UNIT 2886 — Optics
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 35/00 (20130101)

Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 9/02 (20130101)
G01B 9/02003 (20130101)
G01B 9/02079 (20130101)
G01B 9/02081 (20130101)
G01B 2290/55 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/45 (20130101)

Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM]
G01Q 20/02 (20130101)
G01Q 60/24 (20130101)
G01Q 60/38 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/29 (20130101)
G02F 1/3538 (20130101) Original (OR) Class

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/10076 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119665 Das et al.
FUNDED BY
Department of Energy (DOE)
Exascale Computing Project (ECP)
PathForward Project (PATHFORWARD)
Lawrence Livermore National Laboratory (LLNL)
APPLICANT(S) ADVANCED MICRO DEVICES, INC. (Santa Clara, California)
ASSIGNEE(S) ADVANCED MICRO DEVICES, INC. (Santa Clara, California)
INVENTOR(S) Shomit N. Das (Austin, Texas);  Kishore Punniyamurthy (Austin, Texas)
ABSTRACT A processing system scales power to memory and memory channels based on identifying causes of stalls of threads of a wavefront. If the cause is other than an outstanding memory request, the processing system throttles power to the memory to save power. If the stall is due to memory stalls for a subset of the memory channels servicing memory access requests for threads of a wavefront, the processing system adjusts power of the memory channels servicing memory access request for the wavefront based on the subset. By boosting power to the subset of channels, the processing system enables the wavefront to complete processing more quickly, resulting in increased processing speed. Conversely, by throttling power to the remainder of channels, the processing system saves power without affecting processing speed.
FILED Thursday, December 06, 2018
APPL NO 16/212388
ART UNIT 2133 — Memory Access and Control
CURRENT CPC
Electric Digital Data Processing
G06F 3/0625 (20130101) Original (OR) Class
G06F 3/0653 (20130101)
G06F 3/0673 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119923 Farmahini Farahani et al.
FUNDED BY
Department of Energy (DOE)
Lawrence Livermore National Laboratory (LLNL)
APPLICANT(S) Advanced Micro Devices, Inc. (Sunnyvale, California)
ASSIGNEE(S) Advanced Micro Devices, Inc. (Santa Clara, California)
INVENTOR(S) Amin Farmahini Farahani (Santa Clara, California);  Nuwan Jayasena (Sunnyvale, California)
ABSTRACT A cache coherence technique for operating a multi-processor system including shared memory includes allocating a cache line of a cache memory of a processor to a memory address in the shared memory in response to execution of an instruction of a program executing on the processor. The technique includes encoding a shared information state of the cache line to indicate whether the memory address is a shared memory address shared by the processor and a second processor, or a private memory address private to the processor, in response to whether the instruction is included in a critical section of the program, the critical section being a portion of the program that confines access to shared, writeable data.
FILED Thursday, February 23, 2017
APPL NO 15/440979
ART UNIT 2135 — Memory Access and Control
CURRENT CPC
Electric Digital Data Processing
G06F 12/0811 (20130101)
G06F 12/0813 (20130101) Original (OR) Class
G06F 12/0837 (20130101)
G06F 2212/1024 (20130101)
G06F 2212/1041 (20130101)
G06F 2212/1048 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11120990 Warren et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
Alliance for Sustainable Energy, LLC (ASE)
National Renewable Energy Laboratory (NREL)
U.S. Agency for International Development (USAID)
Bureau for Economic Growth, Education, and Environment (EGEE)
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  Colorado School of Mines (Golden, Colorado)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) Emily Lowell Warren (Golden, Colorado);  Theresa Emily Saenz (Golden, Colorado);  Jeramy David Zimmerman (Golden, Colorado)
ABSTRACT The present disclosure relates to a method that includes directing a first precursor that includes a Group III element and a second precursor that includes a Group V element to a chamber containing crystalline silicon, where the crystalline silicon includes a substantially planar surface that is patterned with a plurality of v-grooves and the directing results in the forming of a III-V crystal preferentially on a (111) Si surface of the crystalline silicon.
FILED Monday, July 20, 2020
APPL NO 16/933847
ART UNIT 2812 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/0243 (20130101)
H01L 21/02373 (20130101)
H01L 21/02433 (20130101) Original (OR) Class
H01L 21/02538 (20130101)
H01L 29/20 (20130101)
H01L 29/0657 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11121278 Escarra et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) The Administrators of the Tulane Educational Fund (New Orleans, Louisiana)
ASSIGNEE(S) THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (New Orleans, Louisiana)
INVENTOR(S) Matthew David Escarra (New Orleans, Louisiana);  Benjamin Lewson (New Orleans, Louisiana);  Yaping Ji (New Orleans, Louisiana);  Qi Xu (New Orleans, Louisiana);  Adam Ollanik (Boulder, Colorado)
ABSTRACT The use of photovoltaic (PV) cells to convert solar energy to electricity is becoming increasingly prevalent; however, there are still significant limitations associated with the widespread adoption of PV cells for electricity needs. There is a clear need for a high efficiency solar power system that supplies electricity at a competitive cost and that provides for an on-demand supply of electricity as well as energy storage. By combining aspects of concentrated solar power and concentrated photovoltaics, the present invention provides a device that enables the conversion of sunlight to electricity at very high efficiencies and that enables the transmission of thermal energy to heat storage devices for later use. The disclosed device enables transmissive CPV through the use of a multijunction PV cell mounted on a transparent base. The use of a multijunction cell allows for highly efficient absorption of light above the bandgap of the lowest bandgap subcell. The transparent base permits transmission of a high percentage of the remaining light below the bandgap of the lowest bandgap subcell. The present invention also discloses a method of generating electricity through the use of a transmissive CPV device. Sunlight is concentrated onto one or more surfaces of the device. High energy light is absorbed by a multijunction PV cell and converted directly to electricity, while low energy light is transmitted through the device into a thermal storage device, which may then be coupled to a heat engine to generate dispatchable electricity.
FILED Monday, June 29, 2015
APPL NO 15/322417
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/042 (20130101)
H01L 31/048 (20130101)
H01L 31/0201 (20130101)
H01L 31/0488 (20130101)
H01L 31/0521 (20130101)
H01L 31/0547 (20141201)
H01L 31/0687 (20130101) Original (OR) Class
H01L 31/0693 (20130101)
H01L 31/02168 (20130101)

Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules
H02S 40/44 (20141201)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/52 (20130101)
Y02E 10/60 (20130101)
Y02E 10/544 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11121336 Forrest et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Energy (DOE)
Office of Science (DOEOS)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Stephen R. Forrest (Ann Arbor, Michigan);  Jeramy D. Zimmerman (San Francisco, California);  Xin Xiao (Ann Arbor, Michigan)
ABSTRACT Disclosed herein are organic photosensitive optoelectronic devices comprising two electrodes in superposed relation; a mixed photoactive layer located between the two electrodes, wherein the mixed photoactive layer comprises at least one donor material having a HOMO energy and at least one acceptor material having a LUMO energy, wherein the at least one donor material and the at least one acceptor material form a mixed donor-acceptor heterojunction; a photoactive layer adjacent to and interfacing with the mixed photoactive layer, wherein the photoactive layer comprises a material having a LUMO energy within 0.3 eV of the LUMO energy of the at least one acceptor material or a HOMO energy within 0.3 eV of the HOMO energy of the at least one donor material; and a buffer layer adjacent to and interfacing with the mixed photoactive layer.
FILED Friday, November 22, 2013
APPL NO 14/646154
ART UNIT 2829 — Semiconductors/Memory
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 10/00 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 51/0046 (20130101)
H01L 51/0056 (20130101)
H01L 51/0072 (20130101)
H01L 51/4253 (20130101) Original (OR) Class
H01L 2251/552 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/549 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11121355 Mane et al.
FUNDED BY
Department of Energy (DOE)
Argonne National Laboratory (ANL)
UChicago Argonne, LLC (UCHICAGO)
APPLICANT(S) UChicago Argonne, LLC (Chicago, Illinois)
ASSIGNEE(S) UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Anil U. Mane (Naperville, Illinois);  Jeffrey W. Elam (Elmhurst, Illinois);  Joong Sun Park (Woodridge, Illinois);  Jason R. Croy (Bolingbrook, Illinois)
ABSTRACT The fabrication of robust interfaces between transition metal oxides and non-aqueous electrolytes is one of the great challenges of lithium ion batteries. Atomic layer deposition (ALD) of aluminum tungsten fluoride (AlWxFy) improves the electrochemical stability of LiCoO2. AlWxFy thin films were deposited by combining trimethylaluminum and tungsten hexafluoride. in-situ quartz crystal microbalance and transmission electron microscopy studies show that the films grow in a layer-by-layer fashion and are amorphous nature. Ultrathin AlWxFy coatings (<10 Å) on LiCoO2 significantly enhance stability relative to bare LiCoO2 when cycled to 4.4 V. The coated LiCoO2 exhibited superior rate capability (up to 400 mA/g) and discharge capacities at a current of 400 mA/g were 51% and 92% of the first cycle capacities for the bare and AlWxFy coated materials. These results open new possibilities for designing ultrathin and electrochemically robust coatings of metal fluorides via ALD to enhance the stability of Li-ion electrodes.
FILED Monday, December 03, 2018
APPL NO 16/208381
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 16/30 (20130101)
C23C 16/45531 (20130101)
C23C 16/45555 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/131 (20130101)
H01M 4/366 (20130101)
H01M 4/0421 (20130101) Original (OR) Class
H01M 4/505 (20130101)
H01M 4/628 (20130101)
H01M 4/1391 (20130101)
H01M 10/0525 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11121398 Zhamu et al.
FUNDED BY
Department of Energy (DOE)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Global Graphene Group, Inc. (Dayton, Ohio)
ASSIGNEE(S) Global Graphene Group, Inc. (Dayton, Ohio)
INVENTOR(S) Aruna Zhamu (Springboro, Ohio);  Bor Z. Jang (Centerville, Ohio)
ABSTRACT Provided is a rechargeable alkali metal-sulfur cell comprising an anode active material layer, an electrolyte, and a cathode active material layer comprising multiple particulates, wherein at least one of the particulates comprises one or a plurality of sulfur-containing material particles being embraced or encapsulated by a thin layer of a conductive sulfonated elastomer composite having from 0.01% to 50% by weight of a conductive reinforcement material dispersed in a sulfonated elastomeric matrix material, wherein the conductive reinforcement material is selected from graphene sheets, carbon nanotubes, carbon nanofibers, metal nanowires, conductive polymer fibers, or a combination thereof and the composite has a recoverable tensile strain from 2% to 500%, a lithium ion conductivity from 10−7 S/cm to 5×10−2 S/cm, and a thickness from 0.5 nm to 10 μm. This battery exhibits an excellent combination of high sulfur content, high sulfur utilization efficiency, high energy density, and long cycle life.
FILED Friday, June 15, 2018
APPL NO 16/010213
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/38 (20130101)
H01M 4/133 (20130101)
H01M 4/136 (20130101)
H01M 4/137 (20130101)
H01M 4/364 (20130101)
H01M 4/366 (20130101)
H01M 4/587 (20130101)
H01M 4/604 (20130101)
H01M 4/623 (20130101)
H01M 4/625 (20130101)
H01M 4/5835 (20130101)
H01M 10/052 (20130101)
H01M 10/0525 (20130101) Original (OR) Class
H01M 10/0568 (20130101)
H01M 10/0569 (20130101)
H01M 2004/021 (20130101)
H01M 2004/028 (20130101)
H01M 2300/0037 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11121400 Dai et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOEOS)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Hongjie Dai (Stanford, California);  Michael R. Angell (Stanford, California);  Yingpeng Wu (Stanford, California);  Ming Gong (Stanford, California);  Chunze Yuan (Stanford, California)
ABSTRACT A metal-ion battery includes: 1) an anode including a metal; 2) a cathode; and 3) an ionic liquid electrolyte disposed between the anode and the cathode, wherein the ionic liquid electrolyte corresponds to a mixture of a metal halide and an organic compound.
FILED Wednesday, December 14, 2016
APPL NO 15/781099
ART UNIT 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/38 (20130101)
H01M 4/134 (20130101)
H01M 4/587 (20130101)
H01M 4/622 (20130101)
H01M 4/663 (20130101)
H01M 10/054 (20130101) Original (OR) Class
H01M 10/0569 (20130101)
H01M 50/44 (20210101)
H01M 50/431 (20210101)
H01M 2300/0022 (20130101)
H01M 2300/0045 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11121402 Tepavcevic et al.
FUNDED BY
Department of Energy (DOE)
Argonne National Laboratory (ANL)
UChicago Argonne, LLC (UCHICAGO)
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Sanja Tepavcevic (Chicago, Illinois);  Nigel Hajj Becknell (Glen Ellyn, Illinois);  Pietro Papa Lopes (Woodridge, Illinois);  Dusan Strmcnik (Lemont, Illinois);  Vojislav Stamenkovic (Naperville, Illinois)
ABSTRACT An alternative grid energy storage system is described herein. In one embodiment, an electrochemical cell comprises a high specific surface area cathode (e.g., a cathode comprising a carbon nanofoam paper, a carbon nanotube mesh, a particulate carbon material, electrolytic manganese dioxide, or a manganese dioxide film), a zinc or lead anode (e.g., Zn or Pb foil), a selective ion-conductive separator that does not conduct zinc ions (e.g., a NAFION sulfonated tetrafluoroethylene based fluoropolymer-copolymer separator) between the anode and the cathode, and an aqueous electrolyte comprising a manganese salt (e.g., aqueous manganese sulfate) contacting the electrodes and the separator. A battery comprising two or more of the electrochemical cells electrically connected together in series, parallel, or both, also is described.
FILED Friday, January 31, 2020
APPL NO 16/778175
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/505 (20130101)
H01M 4/587 (20130101)
H01M 4/622 (20130101)
H01M 4/661 (20130101)
H01M 4/663 (20130101)
H01M 4/669 (20130101)
H01M 10/054 (20130101) Original (OR) Class
H01M 50/44 (20210101)
H01M 50/411 (20210101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11121432 Carlson et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) OPTODOT CORPORATION (Devens, Massachusetts)
ASSIGNEE(S) Optodot Corporation (Devens, Massachusetts)
INVENTOR(S) Steven A. Carlson (Cambridge, Massachusetts);  Ifenna Kingsley Anakor (Allston, Massachusetts);  Greg Robert Farrell (Sudbury, Massachusetts)
ABSTRACT Provided are separators for use in an electrochemical cell comprising (a) an inorganic oxide and (b) an organic polymer, wherein the inorganic oxide comprises organic substituents. Also provided are electrochemical cells comprising such separators.
FILED Monday, September 14, 2020
APPL NO 17/019584
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 14/303 (20130101)
C04B 24/00 (20130101)
C04B 24/023 (20130101)
C04B 26/06 (20130101)
C04B 38/0074 (20130101)
C04B 2111/00612 (20130101)
C04B 2111/00801 (20130101)
C04B 2111/00853 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 50/409 (20210101)
H01M 50/411 (20210101)
H01M 50/431 (20210101)
H01M 50/446 (20210101) Original (OR) Class

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/10 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 29/49115 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11121437 Bazzarella et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) 24M Technologies, Inc. (Cambridge, Massachusetts)
ASSIGNEE(S) 24M Technologies, Inc. (Cambridge, Massachusetts)
INVENTOR(S) Ricardo Bazzarella (Woburn, Massachusetts);  Alexander H. Slocum (Bow, New Hampshire);  Tristan Doherty (Somerville, Massachusetts);  James C. Cross, III (Carlisle, Massachusetts)
ABSTRACT Electrochemical cells and methods of making electrochemical cells are described herein. In some embodiments, an apparatus includes a multi-layer sheet for encasing an electrode material for an electrochemical cell. The multi-layer sheet including an outer layer, an intermediate layer that includes a conductive substrate, and an inner layer disposed on a portion of the conductive substrate. The intermediate layer is disposed between the outer layer and the inner layer. The inner layer defines an opening through which a conductive region of the intermediate layer is exposed such that the electrode material can be electrically connected to the conductive region. Thus, the intermediate layer can serve as a current collector for the electrochemical cell.
FILED Friday, December 06, 2019
APPL NO 16/705949
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/0404 (20130101)
H01M 10/0413 (20130101)
H01M 10/0436 (20130101)
H01M 10/0525 (20130101)
H01M 50/10 (20210101)
H01M 50/124 (20210101)
H01M 50/543 (20210101) Original (OR) Class
H01M 50/545 (20210101)
H01M 2220/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11121604 Post
FUNDED BY
Department of Energy (DOE)
Lawrence Livermore National Laboratory (LLNL)
Lawrence Livermore National Security LLC (LLNS)
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Richard F. Post (Walnut Creek, California)
ABSTRACT Robust electro-static (ES) device embodiments, with application to energy storage flywheels as an example, are described that provide reliable, high-efficiency operation in the presence of thermal and mechanical perturbations, as well as seismic events. Electro-static generators and motors, when augmented with magnetic bearings, passive three-dimensional stabilization techniques and dynamic touch-down bearings, enable robust performance in the face of these environmental concerns, as well as efficient operation during typical operational sequences, including spin-up and steady-state modalities.
FILED Saturday, December 28, 2019
APPL NO 16/729317
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Springs; Shock-absorbers; Means for Damping Vibration
F16F 15/315 (20130101)

Dynamo-electric Machines
H02K 7/025 (20130101) Original (OR) Class

Electric Machines Not Otherwise Provided for
H02N 1/002 (20130101)
H02N 1/08 (20130101)
H02N 15/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11121951 Andrade Costa et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Carlos H. Andrade Costa (White Plains, New York);  Chen-Yong Cher (Port Chester, New York);  Yoonho Park (Chappaqua, New York);  Bryan S. Rosenburg (Cortlandt Manor, New York);  Kyung D. Ryu (New City, New York)
ABSTRACT A method for managing a network queue memory includes receiving sensor information about the network queue memory, predicting a memory failure in the network queue memory based on the sensor information, and outputting a notification through a plurality of nodes forming a network and using the network queue memory, the notification configuring communications between the nodes.
FILED Sunday, November 19, 2017
APPL NO 15/817254
ART UNIT 2124 — AI & Simulation/Modeling
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 41/147 (20130101)
H04L 41/0663 (20130101)
H04L 41/0668 (20130101)
H04L 43/0817 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11122079 Aloisio et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOEOS)
APPLICANT(S) Architecture Technology Corporation (Minneapolis, Minnesota)
ASSIGNEE(S) Architecture Technology Corporation (Minneapolis, Minnesota)
INVENTOR(S) Scott Aloisio (Willseyville, New York);  Robert A. Joyce (Ithaca, New York);  Paul Nicotera (Ithaca, New York);  Matthew A. Stillerman (Ithaca, New York)
ABSTRACT An example technique includes initializing, by an obfuscation computing system, communications with nodes in a distributed computing platform. The nodes include compute nodes that provide resources in the distributed computing platform and a controller node that performs resource management of the resources. The obfuscation computing system serves as an intermediary between the controller node and the compute nodes. The technique further includes outputting an interactive user interface (UI) providing a selection between a first privilege level and a second privilege level, and performing one of: based on the selection being for the first privilege level, a first obfuscation mechanism for the distributed computing platform to obfuscate digital traffic between a user computing system and the nodes, or based on the selection being for the second privilege level, a second obfuscation mechanism for the distributed computing platform to obfuscate digital traffic between the user computing system and the nodes.
FILED Monday, April 08, 2019
APPL NO 16/377971
ART UNIT 2491 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/14 (20130101)
G06F 21/6218 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/1425 (20130101)
H04L 63/1475 (20130101)
H04L 63/1491 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 11116211 Joy et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Abraham Joy (Copley, Ohio);  Chao Peng (Tallmadge, Ohio);  Zhuoran Li (Akron, Ohio);  Nicholas Nun (Akron, Ohio);  Apoorva Vishwakarma (Akron, Ohio)
ASSIGNEE(S) The University of Akron (Akron, Ohio)
INVENTOR(S) Abraham Joy (Copley, Ohio);  Chao Peng (Tallmadge, Ohio);  Zhuoran Li (Akron, Ohio);  Nicholas Nun (Akron, Ohio);  Apoorva Vishwakarma (Akron, Ohio)
ABSTRACT A functionalized polyurethane polymer is provided, the polymer defined by the formula
where each R′ is independently derived from a diisocyanate, where each R″ represents the soft segment of the polymer, where n is the number of repeat units within the soft segment of the polymer, where m is the number of repeating mer units in the polymer, where each E is a pendant-functionalized amide unit chain extender, wherein the nitrogen atom of the amide group is part of the polymer backbone. A method for preparing the polymer is also provided.
FILED Wednesday, June 12, 2019
APPL NO 16/438559
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 33/08 (20130101) Original (OR) Class

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 2/23 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 18/10 (20130101)
C08G 18/73 (20130101)
C08G 18/246 (20130101)
C08G 18/758 (20130101)
C08G 18/3206 (20130101)
C08G 18/3821 (20130101)
C08G 18/4854 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 5/18 (20130101)
C08J 2375/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116416 Matthews et al.
FUNDED BY
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Technology Transfer (STTR)
APPLICANT(S) Cardiac Motion, LLC (Truckee, California);  The Regents of The University of California (Oakland, California)
ASSIGNEE(S) Cardiac Motion, LLC (Truckee, California);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Dennis Matthews (Truckee, California);  Xiaoguang Liu (Davis, California);  Songjie Bi (Davis, California)
ABSTRACT The present disclosure describes a method and device to monitor the heart of a subject using radio signals. Availability of a portable heart monitor that can be used in a subject's home can increase patient compliance and improve diagnosis rates of cardiac conditions. A mobile heart monitor can be especially useful to those subjects who are elderly, incapacitated, or do not have easy access to a clinic, doctor's office, or hospital.
FILED Thursday, June 11, 2015
APPL NO 14/736745
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0022 (20130101)
A61B 5/024 (20130101)
A61B 5/361 (20210101)
A61B 5/0507 (20130101) Original (OR) Class
A61B 5/7282 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116816 Soliman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) Extend Biosciences, Inc. (Newton, Massachusetts)
ASSIGNEE(S) Extend Biosciences, Inc. (Newton, Massachusetts)
INVENTOR(S) Tarik Soliman (Cambridge, Massachusetts);  Laura M. Hales (Cambridge, Massachusetts);  Daniel B. Hall (Easton, Massachusetts);  Christopher So (Henderson, Nevada);  Howard P. Sard (Arlington, Massachusetts);  Vishnumurthy Hegde (Chelmsford, Massachusetts)
ABSTRACT The invention provides a parathyroid hormone (PTH) compound comprising a PTH peptide. The PTH compound has a significantly increased bioavailability or circulating half-life when compared to a bioavailability or a circulating half-life of a native form of the PTH peptide. The PTH compound has a significantly greater serum concentration at multiple timepoints post-administration to a rat when compared to that of a native PTH peptide.
FILED Tuesday, January 29, 2019
APPL NO 16/261507
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 38/10 (20130101) Original (OR) Class
A61K 38/22 (20130101)
A61K 47/60 (20170801)
A61K 47/551 (20170801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116848 Bilgicer et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) University of Notre Dame du Lac (South Bend, Indiana)
ASSIGNEE(S) University of Notre Dame du Lac (South Bend, Indiana)
INVENTOR(S) Zihni Basar Bilgicer (Granger, Indiana);  Nathan J. Alves (South Bend, Indiana)
ABSTRACT A method of crosslinking a hetero-bifunctional photo crosslinking compound to an immunoglobulin having at least one heterocyclic photo reactive group and at least one non-photo reactive group where the non-photo reactive group is coupled to an effector molecule and the photo reactive group is coupled to the nucleotide binding site of an immunoglobulin. Alternatively, the photo crosslinker contains an orthogonal reactive group such as a thiol, which can be coupled to an effector molecule or functionalized ligand.
FILED Monday, June 24, 2019
APPL NO 16/450615
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/337 (20130101)
A61K 47/6803 (20170801)
A61K 47/6889 (20170801) Original (OR) Class

Peptides
C07K 16/00 (20130101)
C07K 16/2887 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/531 (20130101)
G01N 33/532 (20130101)
G01N 33/533 (20130101)
G01N 33/54353 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116853 Wang et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Georgia State University Research Foundation, Inc. (Atlanta, Georgia)
ASSIGNEE(S) Georgia State University Research Foundation, Inc. (Atlanta, Georgia)
INVENTOR(S) Gangli Wang (Atlanta, Georgia);  Zhenghua Tang (Miami, Florida);  Cecil Conroy (Decatur, Georgia);  Tarushee Ahuja (Atlanta, Georgia)
ABSTRACT Monolayer protected nanoclusters (MPCs) are described herein. The MPCs contain a cluster of atoms or molecules (e.g. core) having bound thereto a plurality of ligands (e.g., monolayer). The ligands can be bound covalently or semi-covalently bound to the cluster. The ligands are generally in the form of a monolayer or mixed monolayer. The monolayer or mixed monolayer contains a plurality of ligands. In one embodiment, the monolayer and/or mixed monolayer contains 1,4-dithiolate ligands. The MPCs described herein exhibit improved quantum efficiency allowing for single cluster emissions to be measured. Moreover, some embodiments of the MPCs described herein exhibit enhanced redox activity, including the ability to transfer a plurality of electrons, i.e., up to about 19 or up to about 30 electrons under controlled conditions, while displaying improved overall chemical stability. Such behavior can be utilized in catalysis and nanoelectronics applications.
FILED Wednesday, May 15, 2013
APPL NO 14/400846
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/0093 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117117 Ghosh et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas)
ASSIGNEE(S) BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas)
INVENTOR(S) Anindya Ghosh (Little Rock, Arkansas);  Bijay P. Chhetri (Little Rock, Arkansas)
ABSTRACT A method of synthesizing a doped carbonaceous material includes mixing a carbon precursor material with at least one dopant to form a homogeneous/heterogeneous mixture; and subjecting the mixture to pyrolysis in an inert atmosphere to obtain the doped carbonaceous material. A method of purifying water includes providing an amount of the doped carbonaceous material in the water as a photocatalyst; and illuminating the water containing the doped carbonaceous material with visible light such that under visible light illumination, the doped carbonaceous material generates excitons (electron-hole pairs) and has high electron affinity, which react with oxygen and water adsorbed on its surface forming reactive oxygen species (ROS), such as hydroxyl radicals and superoxide radicals, singlet oxygen, hydrogen peroxide, that, in turn, decompose pollutants and micropollutants.
FILED Friday, July 13, 2018
APPL NO 16/034750
ART UNIT 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 21/18 (20130101) Original (OR) Class
B01J 21/063 (20130101)
B01J 21/066 (20130101)
B01J 23/06 (20130101)
B01J 23/10 (20130101)
B01J 23/14 (20130101)
B01J 23/22 (20130101)
B01J 23/26 (20130101)
B01J 23/28 (20130101)
B01J 23/30 (20130101)
B01J 23/36 (20130101)
B01J 23/72 (20130101)
B01J 23/75 (20130101)
B01J 23/462 (20130101)
B01J 23/745 (20130101)
B01J 23/755 (20130101)
B01J 27/04 (20130101)
B01J 27/043 (20130101)
B01J 27/047 (20130101)
B01J 27/051 (20130101)
B01J 31/182 (20130101)
B01J 31/183 (20130101)
B01J 31/1815 (20130101)
B01J 31/1825 (20130101)
B01J 31/2213 (20130101)
B01J 35/004 (20130101)
B01J 37/04 (20130101)
B01J 37/084 (20130101)
B01J 2231/005 (20130101)
B01J 2531/008 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/30 (20130101)
C02F 1/32 (20130101)
C02F 1/283 (20130101)
C02F 1/725 (20130101)
C02F 2101/308 (20130101)
C02F 2201/3222 (20130101)
C02F 2305/10 (20130101)
C02F 2305/023 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117123 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Trustees of Boston College (Chestnut Hill, Massachusetts)
ASSIGNEE(S) The Trustees of Boston College (Chestnut Hill, Massachusetts)
INVENTOR(S) Xiao-Xiang Zhang (Newton, Massachusetts);  Yang Hu (Hockesssin, Delaware)
ABSTRACT In one aspect, the disclosure relates to a mode of asymmetric induction in radical processes based on enhanced hydrogen-bonding capability and the situation of metal centers in cavity-like chiral environments. Also disclosed is an asymmetric system for stereoselective synthesis of cyclopropane and aziridine derivatives. The disclosed Co(II)-based metalloradical system has been shown to have an unusual capability of controlling both the degree and sense of asymmetric induction in cyclopropanation and aziridination reactions in a systematic manner. The disclosed system is applicable to a broad scope of substrates having diazo or azido moieties and exhibits a remarkable profile of reactivity and selectivity, providing access to cyclopropane diastereomers and aziridine enantiomers in highly enantioenriched forms. Also disclosed are catalysts useful in the disclosed processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
FILED Thursday, April 16, 2020
APPL NO 16/851041
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 31/183 (20130101) Original (OR) Class

Acyclic or Carbocyclic Compounds
C07C 67/347 (20130101)
C07C 2601/02 (20170501)

Heterocyclic Compounds
C07D 203/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117911 Therien et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Duke University (Durham, North Carolina)
ASSIGNEE(S) DUKE UNIVERSITY (Durham, North Carolina)
INVENTOR(S) Michael Therien (Durham, North Carolina);  Ting Jiang (Durham, North Carolina);  Nicholas Polizzi (Durham, North Carolina);  Jeffrey Rawson (Durham, North Carolina)
ABSTRACT High-potential photo-oxidants are provided with a supermolecule structure at least including a conjugated macrocycle linked to a metal complex. The conjugated macrocycle is electron-accepting relative to hydrogen or bears electron withdrawing substituents such as fluoroalkyl, fluoroaryl, fluoro, halo, cyano, or nitro. The metal complex is also electron-accepting relative to hydrogen or bears electron withdrawing substituents such as fluoroalkyl, fluoroaryl, fluoro, halo, cyano, or nitro. The linker can be thynyl, vinyl, thiophenyl, diethynylaryl, divinylaryl, diethynyl(unsaturated heterocycloalkenyl), divinyl(unsaturated heterocycloalkenyl), diethynyl(unsaturated heterocycloalkynyl), or divynyl(unsaturated heterocycloalkynyl). A specific implementation is an ethyne-bridged eDef-Rutpy-(porphinato)Zn(II) (eDef-RuPZn) supermolecule.
FILED Tuesday, June 05, 2018
APPL NO 16/000554
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 31/183 (20130101)
B01J 31/1815 (20130101)
B01J 35/004 (20130101)
B01J 2231/70 (20130101)
B01J 2531/025 (20130101)
B01J 2531/26 (20130101)
B01J 2531/0216 (20130101)
B01J 2531/0244 (20130101)
B01J 2531/821 (20130101)
B01J 2540/225 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 15/0053 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117914 Pemberton et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
ASSIGNEE(S) Arizona Board of Regents on behalf of the University of Arizona (Tucson, Arizona)
INVENTOR(S) Jeanne E. Pemberton (Tucson, Arizona);  Robin L. Polt (Tucson, Arizona);  Raina M. Maier (Tucson, Arizona);  Ricardo Palos Pacheco (Tucson, Arizona)
ABSTRACT The present invention provides carbohydrate-based surfactants and methods for producing the same. Methods for producing carbohydrate-based surfactants include using a glycosylation promoter to link a carbohydrate or its derivative to a hydrophobic compound.
FILED Tuesday, November 22, 2016
APPL NO 15/358159
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 3/003 (20130101)
C07F 9/94 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 1/00 (20130101)
C07H 15/04 (20130101)
C07H 15/06 (20130101)
C07H 15/14 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118008 Park et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) International Business Machines Corporation (Armonk, New York);  The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York);  THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California)
INVENTOR(S) Nathaniel H. Park (San Jose, California);  James L. Hedrick (Pleasanton, California);  Victoria A. Piunova (Los Gatos, California);  Dmitry Zubarev (San Jose, California);  Gavin O. Jones (San Jose, California);  Robert M. Waymouth (Palo Alto, California);  Binhong Lin (Stanford, California)
ABSTRACT Techniques regarding the synthesis of one or more polymers through one or more ring-opening polymerizations conducted within a flow reactor and facilitated by one or more anionic catalysts are provided. For example, one or more embodiments can comprise a method, which can comprise polymerizing, via a ring-opening polymerization within a flow reactor, a cyclic monomer in the presence of one or more anionic organocatalysts.
FILED Friday, July 06, 2018
APPL NO 16/028989
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 63/685 (20130101)
C08G 63/823 (20130101)
C08G 64/0208 (20130101) Original (OR) Class
C08G 67/00 (20130101)
C08G 75/26 (20130101)
C08G 79/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118150 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
APPLICANT(S) Research Foundation of the City University of New York (New York, New York);  Memorial Sloan Kettering Cancer Center (New York, New York)
ASSIGNEE(S) Research Foundation of the City University of New York (New York, New York);  Memorial Sloan Kettering Cancer Center (New York, New York)
INVENTOR(S) Sihong Wang (Scarsdale, New York);  A. H. Rezwanuddin Ahmed (New York, New York);  Xuejun Jiang (Cresskill, New Jersey);  Chun-wei Chi (New York, New York);  Chenghai Li (New York, New York)
ABSTRACT A layered, microfluidic array is disclosed. The array has a first layer with a culture channels extending in a first longitudinal direction. Each culture channel includes multiple traps that entrap cell or tissue samples. The array also has a second layer with microfluidic channels extending in a second longitudinal direction that is orthogonal the first longitudinal direction. A third layer, disposed between the first layer and the second layer, has pores arranged within the third layer such that each nest is vertically stacked above, and fluidly connected with, a corresponding culture chamber in the first layer. Each nest is fluidly isolated from adjacent nests by a fluid impermeable region of the third layer such that horizontal diffusion of water within the third layer is prevented.
FILED Thursday, January 10, 2019
APPL NO 16/244797
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502715 (20130101)
B01L 3/502746 (20130101)
B01L 3/502761 (20130101)
B01L 2200/0668 (20130101)
B01L 2300/087 (20130101)
B01L 2300/168 (20130101)
B01L 2300/0816 (20130101)
B01L 2300/0819 (20130101)
B01L 2300/0874 (20130101)
B01L 2300/0887 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 23/16 (20130101) Original (OR) Class
C12M 23/22 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118199 Reddy et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) WOODS HOLE OCEANOGRAPHIC INSTITUTION (Woods Hole, Massachusetts);  WESTERN WASHINGTON UNIVERSITY (Bellingham, Washington);  MARINE BIOLOGICAL LABORATORY (Woods Hole, Massachusetts)
ASSIGNEE(S) WOODS HOLE OCEANOGRAPHIC INSTITUTION (Woods Hole, Massachusetts);  WESTERN WASHINGTON UNIVERSITY (Bellingham, Washington);  MARINE BIOLOGICAL LABORATORY (Woods Hole, Massachusetts)
INVENTOR(S) Christopher M. Reddy (Woods Hole, Massachusetts);  Gregory W. O'Neil (Bellingham, Washington);  Scott R. Lindell (Woods Hole, Massachusetts)
ABSTRACT A method comprising a series of selective extraction techniques for the parallel production of biodiesel and isolation of several valuable co-products including an alkenone hydrocarbon mixture of the kerosene/jet fuel range (primarily C10-, C12-, and C17-hydrocarbons) and fucoxanthin, a high-valued carotenoid, from the marine alkenone-producing microalgae Isochrysis.
FILED Monday, January 28, 2019
APPL NO 16/259339
ART UNIT 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 49/00 (20130101)

Heterocyclic Compounds
C07D 303/32 (20130101)

Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters
C10L 1/19 (20130101)
C10L 1/185 (20130101)
C10L 1/1802 (20130101)
C10L 2200/0476 (20130101)
C10L 2200/0484 (20130101)

Fatty Acids From Fats, Oils or Waxes; Candles; Fats, Oils or Fatty Acids by Chemical Modification of Fats, Oils, or Fatty Acids Obtained Therefrom
C11C 3/003 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/12 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/26 (20130101)
C12P 7/649 (20130101) Original (OR) Class

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 50/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118220 Daugharthy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of General Medical Sciences (NIGMS)
National Institute of Mental Health (NIMH)
U.S. Public Health Service (USPHS)
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Evan R. Daugharthy (Cambridge, Massachusetts);  Richard C. Terry (Carlisle, Massachusetts);  Je-hyuk Lee (Allston, Massachusetts);  George M. Church (Brookline, Massachusetts);  Benjamin W. Pruitt (Cambridge, Massachusetts)
ABSTRACT Methods of volumetric imaging of a three-dimensional matrix of nucleic acids within a cell is provided. An automated apparatus for sequencing and volumetric imaging of a three-dimensional matrix of nucleic acids is provided.
FILED Wednesday, April 17, 2019
APPL NO 16/386337
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/68 (20130101)
C12Q 1/6841 (20130101)
C12Q 1/6841 (20130101)
C12Q 1/6869 (20130101) Original (OR) Class
C12Q 1/6869 (20130101)
C12Q 2543/101 (20130101)
C12Q 2543/101 (20130101)
C12Q 2563/159 (20130101)
C12Q 2563/159 (20130101)
C12Q 2565/601 (20130101)
C12Q 2565/601 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118224 Doudna et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jennifer A. Doudna (Berkeley, California);  Janice S. Chen (Berkeley, California);  Lucas Benjamin Harrington (Berkeley, California);  Enbo Ma (Moraga, California)
ABSTRACT Provided are compositions and methods for detecting a target DNA (double stranded or single stranded) in a sample. In some embodiments, a subject method includes: (a) contacting the sample with: (i) a type V CRISPR/Cas effector protein (e.g., a Cas12 protein such as Cas12a, Cas12b, Cas12c, Cas12d, Cas12e); (ii) a guide RNA (comprising a region that binds to the type V CRISPR/Cas effector protein, and a guide sequence that hybridizes with the target DNA); and (iii) a detector DNA that is single stranded (i.e., a “single stranded detector DNA”) and does not hybridize with the guide sequence of the guide RNA; and (b) measuring a detectable signal produced by cleavage (by the type V CRISPR/Cas effector protein) of the single stranded detector DNA. Also provided are compositions and methods for cleaving single stranded DNAs (e.g., non-target ssDNAs), e.g., inside of a cell.
FILED Tuesday, June 09, 2020
APPL NO 16/896731
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/11 (20130101)
C12N 2310/20 (20170501)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6823 (20130101)
C12Q 1/6823 (20130101)
C12Q 1/6876 (20130101) Original (OR) Class
C12Q 2521/301 (20130101)
C12Q 2521/543 (20130101)
C12Q 2522/101 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118613 Hussein et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) The Regents of the University of Colorado, a body corporate (Boulder, Colorado)
ASSIGNEE(S) The Regents of the University of Colorado, a body corporate (Denver, Colorado)
INVENTOR(S) Mahmoud I. Hussein (Superior, Colorado);  Sedat H. Biringen (Boulder, Colorado);  Osama R. Bilal (Boulder, Colorado);  Alec Kucala (Lafayette, Colorado)
ABSTRACT A phononic material and a method of using a phononic material for use in interacting with a fluid or solid flow are provided. The phononic material includes an interface surface and a subsurface feature. The interface surface is adapted to move in response to a pressure associated with at least one wave in a flow exerted on the interface surface. The subsurface feature extends from the interface surface. The subsurface feature comprises a phononic crystal or locally resonant metamaterial adapted to receive the at least one wave having the at least one frequency based upon the pressure from the flow via the interface surface and alter the phase of the at least one wave. The interface surface is adapted to vibrate at a frequency, phase and amplitude in response to the manipulated/altered phase of the at least one wave.
FILED Tuesday, July 28, 2015
APPL NO 14/811801
ART UNIT 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeroplanes; Helicopters
B64C 21/00 (20130101)
B64C 21/10 (20130101)

Fluid Dynamics, i.e Methods or Means for Influencing the Flow of Gases or Liquids
F15D 1/006 (20130101)
F15D 1/0025 (20130101) Original (OR) Class
F15D 1/0085 (20130101)

Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for
G10K 11/16 (20130101)
G10K 11/162 (20130101)
G10K 11/165 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11118981 Almasri et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Research Office (ARO)
National Science Foundation (NSF)
APPLICANT(S) The Curators of the University of Missouri (Columbia, Missouri)
ASSIGNEE(S) The Curators of the University of Missouri (Columbia, Missouri)
INVENTOR(S) Mahmoud Almasri (Columbia, Missouri);  Edward Kinzel (Columbia, Missouri)
ABSTRACT A metasurface integrated microbolometer having a sensing layer (e.g., SixGeyO1-x-y). The presence of the metasurface provides selectivity with respect to wavelength, polarization and angle-of-incidence. The presence of the metasurface into the microbolometer affects conversion of electromagnetic to thermal energy, thermal response, electrical integration of the microbolometer, and the tradeoff between resistivity and temperature coefficient of resistance, thereby allowing the ability to obtain a sensing with high temperature coefficient of resistance with lower resistivity values than that of films without the metasurface. The presence of the metasurface removes the need for a Fabry-Perot cavity.
FILED Wednesday, April 17, 2019
APPL NO 16/387514
ART UNIT 2884 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 5/20 (20130101) Original (OR) Class
G01J 5/58 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/16 (20130101)
H01L 37/025 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119013 Carter et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) SiMPore, Inc. (West Henrietta, New York)
ASSIGNEE(S) Simpore Inc. (West Henrietta, New York)
INVENTOR(S) Jared A. Carter (Rochester, New York);  Akash S. Patel (Utica, New York);  Cassandra R. Walinski (Lancaster, New York);  James A. Roussie (Rochester, New York)
ABSTRACT Provided are methods, devices, and kits for the isolation of extracellular vesicles using silicon nanomembranes. A method for EV isolation includes the steps of collecting a biofluid sample, contacting the biofluid sample with a pre-filtration membrane, thereby forming a first filtrate and a first retentate, optionally, washing the first retentate of the pre-filtration membrane, contacting the first filtrate from the pre-filtration membrane with a capture membrane, thereb forming a second filtrate and a second retentate, optionally, washing the second retentate, and eluting the second retentate from the capture membrane or lysing the second retentate to recover the contents.
FILED Friday, October 11, 2019
APPL NO 16/600322
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 61/027 (20130101)
B01D 71/022 (20130101)
B01D 2317/025 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502753 (20130101)
B01L 2200/0647 (20130101)
B01L 2300/0681 (20130101)
B01L 2300/0896 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/28 (20130101)
G01N 1/4005 (20130101) Original (OR) Class
G01N 2001/4016 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119061 Yu et al.
FUNDED BY
Department of Health and Human Services (HHS)
Food and Drug Administration (FDA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland)
ASSIGNEE(S) UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland)
INVENTOR(S) Yihua Bruce Yu (Ellicott City, Maryland);  Marc Taraban (Gaithersburg, Maryland);  Yue Feng (Niantic, Connecticut)
ABSTRACT The present invention generally relates to a method of using NMR relaxation rates (R2) of water molecules as an indicator of the extent of aggregation of biopharmaceutical formulations. The biopharmaceutical can be evaluated nondestructively without the vial or container being opened or protective seal compromised (i.e., broken). The method is applicable to all biopharmaceuticals and the water signal obtained by magnetic resonance relaxometry is very strong and sensitive because water is used as the solvent and is present in high (>90%) concentrations in every biopharmaceutical formulation.
FILED Monday, July 27, 2020
APPL NO 16/939424
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 24/08 (20130101) Original (OR) Class
G01N 33/15 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/50 (20130101)
G01R 33/448 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119097 Johnson, Jr. et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Alan T. Johnson, Jr. (Philadelphia, Pennsylvania);  Ye Lu (Philadelphia, Pennsylvania);  Joseph J. Mitala (Rockville, Maryland);  Bohdana Discher (Philadelphia, Pennsylvania);  Brett R. Goldsmith (Philadelphia, Pennsylvania)
ABSTRACT Provided are devices and methods featuring a nanoelectronic interface between graphene devices (for example, field effect transistors or FETs) and biomolecules such as proteins, which in turn provides a pathway for production of bioelectronic devices that combine functionalities of the biomolecular and inorganic components. In one exemplary application, one may functionalize graphene FETs with fluorescent proteins to yield hybrids that respond to light at wavelengths defined by the optical absorption spectrum of the protein. The devices may also include graphene in electronic communication with a biomolecule that preferentially binds to a particular analyte.
FILED Tuesday, November 20, 2012
APPL NO 14/362798
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/582 (20130101)
G01N 33/54306 (20130101) Original (OR) Class
G01N 33/54353 (20130101)
G01N 33/54373 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119159 He et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Marquette University (Milwaukee, Wisconsin)
ASSIGNEE(S) Marquette University (Milwaukee, Wisconsin)
INVENTOR(S) Jiangbiao He (Schenectady, New York);  Nabeel A. O. Demerdash (New Berlin, Wisconsin)
ABSTRACT Systems and methods of diagnosing open-circuit fault in power converters receives a neutral point current value, a switching state of the power converter, and load current values. At least one fault condition is identified based upon the switching state of the power converter and the load current values. The neutral point current value current value is compared to the at least one fault condition. An open circuit fault is determined to be present at the switching state of the power converter based upon the comparison.
FILED Thursday, November 10, 2016
APPL NO 15/775247
ART UNIT 2863 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/40 (20130101)
G01R 31/54 (20200101) Original (OR) Class

Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 7/487 (20130101)
H02M 7/537 (20130101)

Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils
H02P 27/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119165 Nevzorov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
APPLICANT(S) North Carolina State University (Raleigh, North Carolina)
ASSIGNEE(S) North Carolina State University Office of Research Commercialization (Raleigh, North Carolina)
INVENTOR(S) Alexander Nevzorov (Raleigh, North Carolina);  Alexej I. Smirnov (Raleigh, North Carolina);  Sergey Milikisiyants (Raleigh, North Carolina)
ABSTRACT Aspects of photonic band gap resonators for magnetic resonance are described. In one example, an apparatus includes a 1D structure having a plurality of layers. A respective thickness of the individual layers is one-quarter of a respective wavelength of a target magnetic resonance frequency within the individual layers of the plurality of layers, or a multiple thereof. A first layer has a first dielectric constant, and a second layer that is adjacent to the first layer has a second dielectric constant. A defect includes a sample. The defect has a thickness that is approximately up to one-half of a wavelength of the target magnetic resonance frequency within the defect.
FILED Wednesday, June 27, 2018
APPL NO 16/626714
ART UNIT 2866 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/30 (20130101)
G01R 33/341 (20130101)
G01R 33/34007 (20130101) Original (OR) Class
G01R 33/34069 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119193 Cossairt et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) Northwestern University (Evanston, Illinois);  Southern Methodist University (Dallas, Texas)
ASSIGNEE(S) Northwestern University (Evanston, Illinois);  Southern Methodist University (Dallas, Texas)
INVENTOR(S) Oliver Strider Cossairt (Evanston, Illinois);  Fengqiang Li (Evanston, Illinois);  Florian Willomitzer (Evanston, Illinois);  Prasanna V. Rangarajan (Dallas, Texas)
ABSTRACT A system configured to generate images includes one or more narrowband electromagnetic sources configured to emit a first radiation and a second radiation. The system also includes a detector configured to detect first reflected radiation off of an object and second reflected radiation off of the object, where the first reflected radiation results from the first radiation and the second reflected radiation results from the second radiation. The system further includes a processor operatively coupled to the detector and configured to generate an image of the object based at least in part on a first amplitude of the first reflected radiation and a second amplitude of the second reflected radiation. The processor is also configured to determine a depth profile of the object based at least in part on the first reflected radiation and the second reflected radiation detected by the detector.
FILED Thursday, March 28, 2019
APPL NO 16/367532
ART UNIT 2886 — Optics
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 11/2441 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/4815 (20130101) Original (OR) Class
G01S 17/86 (20200101)
G01S 17/89 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119272 Wang et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) OREGON STATE UNIVERSITY (Corvallis, Oregon)
ASSIGNEE(S) OREGON STATE UNIVERSITY (Corvallis, Oregon)
INVENTOR(S) Alan Xiaolong Wang (Corvallis, Oregon);  Erwen Li (Corvallis, Oregon)
ABSTRACT Electrically tunable hybrid silicon-transparent conductive oxide (Si-TCO) devices, such as dual-electrode micro-ring resonators and micro-disks for large-scale on-chip wavelength division multiplexing optical interconnects.
FILED Wednesday, October 14, 2020
APPL NO 17/069920
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/12007 (20130101) Original (OR) Class
G02B 6/29338 (20130101)
G02B 2006/121 (20130101)
G02B 2006/12164 (20130101)

Multiplex Communication
H04J 14/022 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119771 Tu et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida)
ASSIGNEE(S) UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida)
INVENTOR(S) Yicheng Tu (Tampa, Florida);  Napath Pitaksirianan (Tampa, Florida)
ABSTRACT Disclosed are various embodiments for computing 2-body statistics on graphics processing units (GPUs). Various types of two-body statistics (2-BS) are regarded as essential components of data analysis in many scientific and computing domains. However, the quadratic complexity of these computations hinders timely processing of data. According, various embodiments of the present disclosure involve parallel algorithms for 2-BS computation on Graphics Processing Units (GPUs). Although the typical 2-BS problems can be summarized into a straightforward parallel computing pattern, traditional wisdom from (general) parallel computing often falls short in delivering the best possible performance. Therefore, various embodiments of the present disclosure involve techniques to decompose 2-BS problems and methods for effective use of computing resources on GPUs. We also develop analytical models that guide users towards the appropriate parameters of a GPU program. Although 2-BS problems share the same core computations, each 2-BS problem however carries its own characteristics that calls for different strategies in code optimization. Accordingly, various embodiments of the present disclosure involve a software framework that automatically generates high-performance GPU code based on a few parameters and short primer code input.
FILED Thursday, July 25, 2019
APPL NO 16/521852
ART UNIT 2183 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 9/30043 (20130101)
G06F 9/30098 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11120968 Hujsak et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Research Laboratory (AFRL)
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Karl A. Hujsak (Evanston, Illinois);  Vinayak P. Dravid (Glenview, Illinois)
ABSTRACT Aspects of the present disclosure involve applying a Multi-Objective Autonomous Dynamic Sampling algorithm in an electron or other radiation/charged-particle microscope for the characterization of elemental, chemical, and crystallographic information with over an order of magnitude improvement in time and exposure.
FILED Thursday, October 25, 2018
APPL NO 16/758326
ART UNIT 2881 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/2251 (20130101)
G01N 2223/402 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 37/28 (20130101) Original (OR) Class
H01J 2237/24485 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11120984 Cooks et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Robert Graham Cooks (West Lafayette, Indiana);  Jason Duncan (Dayton, Indiana);  Joshua Wiley (Lafayette, Indiana)
ABSTRACT The invention generally relates to ion traps and methods of use thereof. In certain embodiments, the invention provides a system that includes a mass spectrometer including an ion trap, and a central processing unit (CPU). The CPU has storage that is coupled to the CPU for storing instructions that when executed by the CPU cause the system to apply a constant radio frequency (RF) signal to the ion trap, and apply a first alternating current (AC) signal to the ion trap the frequency of which varies as a function of time.
FILED Friday, October 21, 2016
APPL NO 15/769998
ART UNIT 2881 — Optics
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 49/0031 (20130101)
H01J 49/422 (20130101)
H01J 49/426 (20130101) Original (OR) Class
H01J 49/427 (20130101)
H01J 49/4285 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11121267 Zou et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
Division of Civil and Mechanical Systems (CMS)
APPLICANT(S) BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas)
ASSIGNEE(S) BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas)
INVENTOR(S) Min Zou (Fayetteville, Arkansas);  Corey Thompson (Springdale, Arkansas);  Robert A. Fleming (Fayetteville, Arkansas)
ABSTRACT One aspect of the disclosure is directed to a method for forming an antireflective coating on a substrate, which includes providing a polymer solution and a silica solution, depositing the polymer solution on a surface of the substrate to forming a polymer film thereon, depositing the silica solution on the formed polymer film on the substrate to form a silica film thereon, thereby forming a stack structure having the silica film formed on the polymer film that is, in turn, formed on the substrate, and drying the stack structure to form the antireflective coating on the substrate, wherein the antireflective coating comprises silica nanoparticles.
FILED Monday, March 03, 2014
APPL NO 14/771451
ART UNIT 1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials
C03C 17/001 (20130101)
C03C 17/32 (20130101)
C03C 17/42 (20130101)
C03C 2217/734 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/118 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/02168 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11121328 Li et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
ASSIGNEE(S) Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) Jian Li (Tempe, Arizona);  Eric Turner (Phoenix, Arizona)
ABSTRACT Platinum and palladium complexes are disclosed that can be useful as narrow band phosphorescent emitters. Also disclosed are methods for preparing and using the platinum and palladium complexes.
FILED Tuesday, September 01, 2020
APPL NO 17/008762
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 15/0086 (20130101)

Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 11/06 (20130101)
C09K 2211/185 (20130101)
C09K 2211/1044 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 51/0087 (20130101) Original (OR) Class
H01L 51/5016 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11121334 Sonkusale et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Trustees of Tufts College (Medford, Massachusetts)
ASSIGNEE(S) Trustees of Tufts College (Medford, Massachusetts)
INVENTOR(S) Sameer Sonkusale (Arlington, Massachusetts);  Shideh Kabiri Ameri Abootorabi (Medford, Massachusetts);  Pramod Kumar Singh (Ambedkar Nagar, India)
ABSTRACT A field effect transistor having a channel that comprises three-dimensional graphene foam. The subject matter of the invention concerns a three dimensional field-effect transistor having a channel based on graphene foam and the use of ionic liquid as a gate. The graphene foam is made of a three-dimensional network of single and double layer graphene that extends in all the three dimensions. Metal contacts on either end of the graphene foam form the drain and source contacts of the transistor.
FILED Friday, June 26, 2015
APPL NO 15/321296
ART UNIT 2893 — Semiconductors/Memory
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/1473 (20130101)
A61B 5/14528 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/4145 (20130101)
G01N 27/4146 (20130101)

Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 9/2013 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 29/0665 (20130101)
H01L 29/778 (20130101)
H01L 29/1606 (20130101)
H01L 51/0045 (20130101)
H01L 51/0558 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11121896 Bendlin et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) AT and T Intellectual Property I, L.P. (Atlanta, Georgia);  University of Notre Dame du Lac (South Bend, Indiana)
ASSIGNEE(S) AT and T Intellectual Property I, L.P. (Atlanta, Georgia);  University of Notre Dame du Lac (South Bend, Indiana)
INVENTOR(S) Ralf Bendlin (Cedar Park, Texas);  Aditya Chopra (Austin, Texas);  Bertrand Martyn Hochwald (South Bend, Indiana);  Nicholas Joseph Estes (South Bend, Indiana);  Jonathan David Chisum (South Bend, Indiana);  Kang Gao (San Diego, California)
ABSTRACT Aspects of the subject disclosure may include, for example, receiving a radio frequency (RF) signal having a carrier wave component that operates at a carrier frequency within a millimeter wave spectrum. The RF signal also includes an information component based on a phase shift keying (PSK) modulation of the carrier wave component. A local oscillator (LO) signal is obtained, which includes an LO frequency that approximates the carrier frequency. The received RF signal and the LO signal are combined without using signal multiplication to obtain a first combined output signal. The first combined output signal being detected via a non-linear energy detector to obtain a first detected signal. The first output signal includes information of the information component. Other embodiments are disclosed.
FILED Tuesday, November 24, 2020
APPL NO 17/103152
ART UNIT 2631 — Digital Communications
CURRENT CPC
Transmission
H04B 7/0413 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 27/22 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11121962 Michael et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) VMware, Inc. (Palo Alto, California)
ASSIGNEE(S) VMWARE, INC. (Palo Alto, California)
INVENTOR(S) Nithin Michael (San Francisco, California);  Ao Tang (San Francisco, California);  Victor de Souza Lima e Silva (San Francisco, California);  Thiago Sousa Santos (San Francisco, California);  Ning Wu (San Francisco, California);  Archit Baweja (San Francisco, California);  Ki Suh Lee (San Francisco, California);  Yao Wang (San Francisco, California);  Andrey Gushchin (San Francisco, California);  Sakethnath Are (San Francisco, California)
ABSTRACT A method comprising instantiating virtual routers (VRs) at each of a set of nodes that form a network. Each VR is coupled to the network and to a tenant of the node. The network comprises virtual links in an overlay network provisioned over an underlay network including servers of a public network. The method comprises configuring at least one VR to include a feedback control system comprising at least one objective function that characterizes the network. The method comprises configuring the VR to receive link state data of a set of virtual links of the virtual links, and control routing of a tenant traffic flow of each tenant according to a best route of the network determined by the at least one objective function using the link state data.
FILED Tuesday, April 09, 2019
APPL NO 16/378689
ART UNIT 2465 — Multiplex and VoIP
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 43/0864 (20130101)
H04L 43/0876 (20130101)
H04L 45/22 (20130101) Original (OR) Class
H04L 45/24 (20130101)
H04L 45/745 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 11116416 Matthews et al.
FUNDED BY
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Technology Transfer (STTR)
APPLICANT(S) Cardiac Motion, LLC (Truckee, California);  The Regents of The University of California (Oakland, California)
ASSIGNEE(S) Cardiac Motion, LLC (Truckee, California);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Dennis Matthews (Truckee, California);  Xiaoguang Liu (Davis, California);  Songjie Bi (Davis, California)
ABSTRACT The present disclosure describes a method and device to monitor the heart of a subject using radio signals. Availability of a portable heart monitor that can be used in a subject's home can increase patient compliance and improve diagnosis rates of cardiac conditions. A mobile heart monitor can be especially useful to those subjects who are elderly, incapacitated, or do not have easy access to a clinic, doctor's office, or hospital.
FILED Thursday, June 11, 2015
APPL NO 14/736745
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0022 (20130101)
A61B 5/024 (20130101)
A61B 5/361 (20210101)
A61B 5/0507 (20130101) Original (OR) Class
A61B 5/7282 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116765 Gonda et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) GRIFOLS, S.A. (Los Angeles, California)
ASSIGNEE(S) GRIFOLS, S.A. (Los Angeles, California)
INVENTOR(S) Igor Gonda (San Francisco, California);  James Blanchard (El Granada, California);  David C. Cipolla (San Ramon, California);  Luiz Eduardo Moreira Bermudez (Corvallis, Oregon)
ABSTRACT Methods of treatment of NTM lung infections using formulations of liposomal ciprofloxacin. Specific liposome formulations and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described.
FILED Friday, June 26, 2020
APPL NO 16/914122
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/12 (20130101)
A61K 9/0073 (20130101)
A61K 9/0078 (20130101)
A61K 9/127 (20130101)
A61K 31/496 (20130101) Original (OR) Class
A61K 45/06 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11116827 Jones et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Materiel Development Activity (USAMMDA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) ETUBICS CORPORATION (Seattle, Washington)
ASSIGNEE(S) Etubics Corporation (Seattle, Washington)
INVENTOR(S) Frank R. Jones (Seattle, Washington);  Joseph Balint (Seattle, Washington);  Elizabeth Gabitzsch (Seattle, Washington)
ABSTRACT In certain embodiments, methods and compositions are provided for generating immune responses against tumor antigens such as antigens or epitopes of HER1, HER2/neu, HER3, HER4, or any combination thereof. In particular embodiments, there may be provided methods for constructing and producing recombinant adenovirus-based vector vaccines containing nucleic acid sequences encoding tumor antigens such as antigens or epitopes of HER1, HER2/neu, HER3, HER4, or any combination thereof, that allow for vaccinations in individuals with preexisting immunity to adenovirus.
FILED Saturday, June 02, 2018
APPL NO 16/615925
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/00117 (20180801)
A61K 39/001106 (20180801) Original (OR) Class
A61K 39/001152 (20180801)
A61K 2039/523 (20130101)

Peptides
C07K 16/2827 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
C12N 2710/10343 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11121398 Zhamu et al.
FUNDED BY
Department of Energy (DOE)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Global Graphene Group, Inc. (Dayton, Ohio)
ASSIGNEE(S) Global Graphene Group, Inc. (Dayton, Ohio)
INVENTOR(S) Aruna Zhamu (Springboro, Ohio);  Bor Z. Jang (Centerville, Ohio)
ABSTRACT Provided is a rechargeable alkali metal-sulfur cell comprising an anode active material layer, an electrolyte, and a cathode active material layer comprising multiple particulates, wherein at least one of the particulates comprises one or a plurality of sulfur-containing material particles being embraced or encapsulated by a thin layer of a conductive sulfonated elastomer composite having from 0.01% to 50% by weight of a conductive reinforcement material dispersed in a sulfonated elastomeric matrix material, wherein the conductive reinforcement material is selected from graphene sheets, carbon nanotubes, carbon nanofibers, metal nanowires, conductive polymer fibers, or a combination thereof and the composite has a recoverable tensile strain from 2% to 500%, a lithium ion conductivity from 10−7 S/cm to 5×10−2 S/cm, and a thickness from 0.5 nm to 10 μm. This battery exhibits an excellent combination of high sulfur content, high sulfur utilization efficiency, high energy density, and long cycle life.
FILED Friday, June 15, 2018
APPL NO 16/010213
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/38 (20130101)
H01M 4/133 (20130101)
H01M 4/136 (20130101)
H01M 4/137 (20130101)
H01M 4/364 (20130101)
H01M 4/366 (20130101)
H01M 4/587 (20130101)
H01M 4/604 (20130101)
H01M 4/623 (20130101)
H01M 4/625 (20130101)
H01M 4/5835 (20130101)
H01M 10/052 (20130101)
H01M 10/0525 (20130101) Original (OR) Class
H01M 10/0568 (20130101)
H01M 10/0569 (20130101)
H01M 2004/021 (20130101)
H01M 2004/028 (20130101)
H01M 2300/0037 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11121523 Deppe
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Research Laboratory (ARL)
Army Research Office (ARO)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida)
ASSIGNEE(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida)
INVENTOR(S) Dennis G. Deppe (Oviedo, Florida)
ABSTRACT A semiconductor heterostructure device includes a middle layer including an inner conducting channel and an outer current blocking region. A depleted heterojunction current blocking region (DHCBR) is within the outer current blocking region. The DHCBR includes a first depleting impurity specie including a Column II acceptor, and a second depleting impurity comprising oxygen which increases a depletion of the DHCBR so that the DHCBR forces current to flow into the conducting channel during electrical biasing under normal operation of the semiconductor heterostructure device.
FILED Tuesday, October 08, 2019
APPL NO 16/595560
ART UNIT 2817 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/046 (20130101)
H01L 29/165 (20130101)
H01L 29/0619 (20130101)
H01L 29/1608 (20130101)
H01L 29/7395 (20130101)
H01L 29/7828 (20130101)
H01L 29/8083 (20130101)
H01L 33/145 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 5/2063 (20130101)
H01S 5/18308 (20130101) Original (OR) Class
H01S 5/18358 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 11116150 Martin et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia);  Active Influence and Scientific Management, SP (San Angelo, Texas)
ASSIGNEE(S) The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia);  Active Influence and Scientific Management, SP (Lubbock, Texas)
INVENTOR(S) Daniel E. Martin (College Station, Texas);  Arquimedes Ruiz-Columbie (San Angelo, Texas)
ABSTRACT The system uses a specifically modified spray assembly to spray electrically charged fluid below selected clouds so that an updraft carries the charged fluid into the cloud and induces precipitation. The size, charge, and design of the sprayers are specifically designed to elicit precipitation.
FILED Monday, April 08, 2019
APPL NO 16/377276
ART UNIT 3752 — Fluid Handling and Dispensing
CURRENT CPC
Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering
A01G 15/00 (20130101) Original (OR) Class

Spraying Apparatus; Atomising Apparatus; Nozzles
B05B 5/0255 (20130101)

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 1/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11117841 Slater et al.
FUNDED BY
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
Institute of Bioenergy, Climate, and Environment (IBCE)
APPLICANT(S) S2G VENTURES FUND II, L.P. (Chicago, Illinois)
ASSIGNEE(S) S2G VENTURES FUND II, L.P. (Chicago, Illinois)
INVENTOR(S) Steven C. Slater (Manchester, Washington);  Mauricio Avila-Segura (Madison, Wisconsin);  Margaret F. Phillips (McFarland, Wisconsin);  Lisa Leilani Z. Durand (Madison, Wisconsin);  Gary F. Zimmer (Madison, Wisconsin)
ABSTRACT Provided herein is technology relating to organic fertilizers and particularly, but not exclusively, to organic and/or biodegradable flocculants, methods of preparing organic fertilizers using an organic and/or biodegradable flocculant, and systems for treating water using an organic and/or biodegradable flocculant to prepare an organic fertilizer.
FILED Tuesday, July 23, 2019
APPL NO 16/519454
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Organic Fertilisers Not Covered by Subclasses C05B, C05C, e.g Fertilisers From Waste or Refuse
C05F 17/10 (20200101)
C05F 17/40 (20200101) Original (OR) Class

Mixtures of Fertilisers Covered Individually by Different Subclasses of Class C05; Mixtures of One or More Fertilisers With Materials Not Having a Specific Fertilising Activity, e.g Pesticides, Soil-conditioners, Wetting Agents; Fertilisers Characterised by Their Form
C05G 5/12 (20200201)
C05G 5/45 (20200201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US PP33473 Goffreda et al.
FUNDED BY
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey)
ASSIGNEE(S) Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
INVENTOR(S) Joseph C. Goffreda (Columbus, New Jersey);  Anna M. Voordeckers (East Windsor, New Jersey)
ABSTRACT A new and distinct peach variety of Prunus persica named ‘NJ360’ is provided. This variety is distinguished from other peach varieties by its unique combination of showy flowers, medium to large, round, semi-freestone fruit, with a red to greyed-purple blush over a bright yellow-white ground, ripening in mid-season, and possessing aromatic, sweet, sub-acid flavor.
FILED Friday, November 06, 2020
APPL NO 17/091077
ART UNIT 1661 — Plants
CURRENT CPC
Plants
PLT/197
VIEW PATENT @ USPTO:  Full Text   PDF 
US PP33474 Goffreda et al.
FUNDED BY
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey)
ASSIGNEE(S) Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
INVENTOR(S) Joseph C. Goffreda (Columbus, New Jersey);  Anna M. Voordeckers (East Windsor, New Jersey)
ABSTRACT A new and distinct peach variety of Prunus persica named ‘NJ361’ is provided. This variety is distinguished from other peach varieties by its unique combination of showy flowers, medium to large, round, semi-freestone fruit, with a red to greyed-purple blush over a unique bright yellow-orange ground, ripening in mid-season, and possessing aromatic, sweet, acidic flavor.
FILED Friday, November 06, 2020
APPL NO 17/091108
ART UNIT 1661 — Plants
CURRENT CPC
Plants
PLT/197
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 11118784 Sweeney et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Rolls-Royce North American Technologies, Inc. (Indianapolis, Indiana)
ASSIGNEE(S) Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana)
INVENTOR(S) Patrick C. Sweeney (Indianapolis, Indiana);  Douglas J. Snyder (Carmel, Indiana)
ABSTRACT Fuel-air heat exchange system and methods thereof for use in a gas turbine engine. The fuel-air heat exchanger allows heat transfer between a flow of cooling air used to cool components of the engine and a flow of fuel used to drive the engine.
FILED Thursday, May 11, 2017
APPL NO 15/592777
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 3/06 (20130101)
F02C 7/222 (20130101)
F02C 7/232 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2240/35 (20130101)
F05D 2260/20 (20130101)
F05D 2260/232 (20130101)

Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers
F23R 3/283 (20130101) Original (OR) Class

Climate Change Mitigation Technologies Related to Transportation
Y02T 50/60 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119072 Prasad
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
INVENTOR(S) Narasimha S. Prasad (Yorktown, Virginia)
ABSTRACT A system for monitoring vibrations in a target region of interest may include a pulsed laser transmitter assembly, interferometric, telescope, and receiver optics, a photo-EMF detector assembly, signal conditioning/processing electronics, and a monitoring circuit/display. The detector assembly, which has a photo-EMF detector and amplifier circuits, generates an output signal indicative of the vibrations. A laser module outputs a source beam at a PRF of at least 2 Hz. A beam splitter device splits the source beam into separate interrogating and reference beams. The mirror directs the reference beam onto the photo-EMF detector for interference with a reflected return signal. The telescope optics generates an amplified return signal, and directs the amplified return signal to the photo-emf detector. The monitoring computer compares the output signal from the signal processor to a baseline to ascertain a difference therebetween, and generates a diagnostic signal indicative of the difference.
FILED Friday, August 09, 2019
APPL NO 16/536467
ART UNIT 2886 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0006 (20130101)
A61B 5/0245 (20130101)
A61B 5/316 (20210101)
A61B 5/02405 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/39 (20130101)
G01N 21/45 (20130101)
G01N 21/1702 (20130101)
G01N 29/46 (20130101)
G01N 29/2418 (20130101) Original (OR) Class
G01N 2021/1704 (20130101)
G01N 2021/1761 (20130101)
G01N 2021/3125 (20130101)
G01N 2021/3185 (20130101)
G01N 2201/0221 (20130101)
G01N 2291/0255 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11119223 Dill et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
INVENTOR(S) Evan T. Dill (Poquoson, Virginia);  Russell V. Gilabert (Hampton, Virginia)
ABSTRACT A device and method which improves the accuracy of a global positioning system (GPS)-equipped mobile device. A time-stamped first set of GPS data is received via a GPS receiver, e.g., of the base station. A second set of GPS data describing a geoposition of the mobile device is received from the mobile device by the base station. A time of collection of the GPS data coincides. The GPS data includes code, carrier-phase, and pseudo-range information from each of the GPS satellites. A predetermined GPS position correction technique is used to generate a first corrected geoposition of the mobile device using the GPS data. Corrected, carrier-smoothed geoposition is generated as a second corrected geoposition using a carrier smoothing operation. The second corrected geoposition is transmitted to the mobile device and/or an external response system such as a drone or first responder.
FILED Friday, February 01, 2019
APPL NO 16/265408
ART UNIT 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 19/22 (20130101)
G01S 19/41 (20130101) Original (OR) Class
G01S 19/43 (20130101)
G01S 19/071 (20190801)
G01S 19/073 (20190801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11121518 Wroblewski
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Adam C. Wroblewski (North Olmsted, Ohio)
ABSTRACT An optical transmitter includes a beam steering system configured to direct an optical beam through a first optical element towards a second optical element. The beam steering system includes an adjustable optical element. The second optical element is susceptible to thermal and vibrational loads that disrupt an alignment between the first and second optical elements. The second optical element includes a main portion configured to direct the optical beam down a propagation path including a communications target. The second optical element also includes a reflective portion configured to direct an alignment portion of the optical beam back to the beam steering system through the first optical element. A detector is configured to receive the alignment portion and generate an alignment signal. A controller is configured to adjust the adjustable optical element based on the alignment signal to counteract the loads.
FILED Monday, August 20, 2018
APPL NO 15/999560
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 7/003 (20130101)
G02B 27/283 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/0071 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 11116463 Cheng et al.
FUNDED BY
Department of Homeland Security (DHS)
Science and Technology Directorate (DHS-S&T)
Transportation Security Administration (TSA)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Yao-Te Cheng (Sunnyvale, Canada);  Ludwig Galambos (Menlo Park, California);&