FedInvent™ Patents
Patent Details for Tuesday, September 28, 2021
This page was updated on Wednesday, September 29, 2021 at 05:58 PM GMT
Department of Health and Human Services (HHS)
| US 11129543 | Neu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado (Denver, Colorado); Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | The Regents of the University of Colorado (Denver, Colorado) |
| INVENTOR(S) | Corey P. Neu (Boulder, Colorado); Robert L. Wilson (Boulder, Colorado); David Reiter (Decatur, Georgia) |
| ABSTRACT | A process for more sensitive characterization of tissue composition for generating a quantitative MRI (qMRI) map and corresponding delta analysis. Intervertebral disc degeneration (IVDD), resulting in the depletion of hydrophilic glycosaminoglycans (GAGs) located in the nucleus pulposus (NP), can lead to debilitating neck and back pain. Magnetic Resonance Imaging (MRI) is a promising means of IVD assessment due to the correlation between GAG content and MRI relaxation values. T1 and T2 relaxation data were obtained from healthy cervical IVDs, and relaxation data was modeled using both conventional and stretched exponential (SE) decays. Normalized histograms of the resultant quantitative MRI (qMRI) maps were fit with stable distributions. SE models fit relaxation behavior with lower error compared to monoexponential models, indicating anomalous relaxation behavior in healthy IVDs. SE model parameters T1 and T1 increased with IVD segment, while conventional monoexponential measures did not vary. The improved model fit and correlation between both SE T1 and T1 with IVD level suggests these parameters are more sensitive biomarkers for detection of GAG content variation. |
| FILED | Monday, July 08, 2019 |
| APPL NO | 17/259134 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Original (OR) Class A61B 5/0515 (20130101) A61B 5/742 (20130101) A61B 5/4566 (20130101) A61B 2560/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11129562 | Roberts et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | David W. Roberts (Lyme, New Hampshire); Keith D. Paulsen (Hanover, New Hampshire); Alexander Hartov (Enfield, New Hampshire); Songbai Ji (Hanover, New Hampshire); Xiaoyao Fan (Lebanon, New Hampshire) |
| ABSTRACT | A surgical guidance system has two cameras to provide stereo image stream of a surgical field; and a stereo viewer. The system has a 3D surface extraction module that generates a first 3D model of the surgical field from the stereo image streams; a registration module for co-registering annotating data with the first 3D model; and a stereo image enhancer for graphically overlaying at least part of the annotating data onto the stereo image stream to form an enhanced stereo image stream for display, where the enhanced stereo stream enhances a surgeon's perception of the surgical field. The registration module has an alignment refiner to adjust registration of the annotating data with the 3D model based upon matching of features within the 3D model and features within the annotating data; and in an embodiment, a deformation modeler to deform the annotating data based upon a determined tissue deformation. |
| FILED | Monday, February 10, 2020 |
| APPL NO | 16/785882 |
| ART UNIT | 2485 — Recording and Compression |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 5/0077 (20130101) A61B 5/369 (20210101) A61B 5/377 (20210101) Original (OR) Class A61B 2034/104 (20160201) A61B 2034/105 (20160201) A61B 2034/107 (20160201) A61B 2090/367 (20160201) Image Data Processing or Generation, in General G06T 3/0068 (20130101) G06T 7/33 (20170101) G06T 2207/10012 (20130101) G06T 2207/10064 (20130101) G06T 2207/10072 (20130101) G06T 2207/30016 (20130101) Pictorial Communication, e.g Television H04N 13/239 (20180501) H04N 13/257 (20180501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11129774 | Stewart et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (Toronto, Canada) |
| ASSIGNEE(S) | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (Toronto, Canada) |
| INVENTOR(S) | Cameron Alexander Stewart (Springwater, Canada); Benjamin David Hatton (Toronto, Canada); Yoav Finer (Toronto, Canada) |
| ABSTRACT | A biocompatible composite material for controlled release is disclosed, comprising a biocompatible metal oxide structure with a loaded network of pores. The pore network of the biocompatible composite material is filled with a uniformly distributed biologically active micellizing amphiphilic molecule, the size of these pores ranging from about 0.5 to about 100 nanometers. The material is characterized in that when exposed to phosphate-buffered saline (PBS), the controlled release of the active amphiphilic molecule is predominantly diffusion-driven over time. |
| FILED | Tuesday, May 16, 2017 |
| APPL NO | 16/301773 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/08 (20130101) A01N 43/40 (20130101) A01N 47/44 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 6/20 (20200101) A61K 6/30 (20200101) A61K 6/35 (20200101) A61K 6/40 (20200101) A61K 6/40 (20200101) A61K 6/54 (20200101) A61K 6/71 (20200101) A61K 6/74 (20200101) A61K 6/76 (20200101) A61K 6/80 (20200101) A61K 6/84 (20200101) Original (OR) Class A61K 6/86 (20200101) A61K 6/802 (20200101) A61K 6/849 (20200101) A61K 6/853 (20200101) A61K 6/864 (20200101) A61K 6/871 (20200101) A61K 9/0024 (20130101) A61K 9/0063 (20130101) A61K 9/143 (20130101) A61K 9/5115 (20130101) A61K 31/20 (20130101) A61K 31/155 (20130101) A61K 31/444 (20130101) A61K 31/785 (20130101) A61K 31/4425 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/10 (20130101) A61L 27/12 (20130101) A61L 27/025 (20130101) A61L 27/32 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/105 (20130101) A61L 27/306 (20130101) A61L 27/425 (20130101) A61L 27/427 (20130101) A61L 27/446 (20130101) A61L 2300/206 (20130101) A61L 2300/208 (20130101) A61L 2300/404 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/02 (20180101) A61P 31/02 (20180101) A61P 31/04 (20180101) Acyclic or Carbocyclic Compounds C07C 279/14 (20130101) C07C 279/26 (20130101) Heterocyclic Compounds C07D 213/20 (20130101) C07D 213/74 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/22 (20130101) C08K 3/32 (20130101) C08K 2003/325 (20130101) C08K 2003/2227 (20130101) C08K 2003/2237 (20130101) C08K 2003/2296 (20130101) Compositions of Macromolecular Compounds C08L 33/08 (20130101) C08L 33/08 (20130101) C08L 33/12 (20130101) C08L 2203/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11129790 | Zhou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Zhaohui Sunny Zhou (Wellesley, Massachusetts); George O'Doherty (Boston, Massachusetts); Shanshan Liu (Boston, Massachusetts); Kevin Ryan Moulton (Brighton, Massachusetts); Lincoln Ombelets (Boston, Massachusetts); Amissi Sadiki (Boston, Massachusetts) |
| ABSTRACT | A method is provided for reversibly modifying a protein or peptide on its glutamine residue(s) by performing a reaction, such as a transglutaminase-catalyzed reaction, between the protein or peptide and an amine-containing reagent, whereby the reagent is linked through its amine function to a side chain of the glutamine residue. Subjecting the modified protein to an appropriate stimulus regenerates the protein or peptide in its original form. |
| FILED | Monday, May 21, 2018 |
| APPL NO | 15/985494 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0002 (20130101) Original (OR) Class Peptides C07K 1/13 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1044 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/06 (20130101) Enzymes C12Y 203/02013 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11129825 | Jenkins |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Elysium Therapeutics, Inc. (Danville, California) |
| ASSIGNEE(S) | ELYSIUM THERAPEUTICS, INC. (Akron, Ohio) |
| INVENTOR(S) | Thomas E. Jenkins (Half Moon Bay, California) |
| ABSTRACT | The invention provides compositions and methods for the treatment or prevention of pain. The invention provides constructs whereby hydrolysis of the construct by a specified gastrointestinal enzyme directly, or indirectly, releases an opioid when taken orally as prescribed. The gastrointestinal enzyme mediated release of opioid from constructs of the invention is designed to be attenuated in vivo via a saturation or inhibition mechanism when overdoses are ingested. The invention further provides constructs that are highly resistant to oral overdose, chemical tampering, and abuse via non-oral routes of administration. |
| FILED | Tuesday, February 26, 2019 |
| APPL NO | 16/286096 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/485 (20130101) Original (OR) Class A61K 47/55 (20170801) A61K 47/61 (20170801) A61K 47/64 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11129830 | Hergenrother et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Paul J. Hergenrother (Champaign, Illinois); Jessie Peh (Champaign, Illinois) |
| ABSTRACT | Compositions and methods for the induction of cancer cell death. The compositions and methods of using them include use of compositions in therapy for the treatment of cancer and for the selective induction of apoptosis in cancer cells. The drug combinations described herein can be synergistic and can have lower neurotoxicity effects than the same amounts of other compounds and combinations of compounds and can be effective when a particular cancer has become resistant to previously administered therapies. |
| FILED | Monday, June 10, 2019 |
| APPL NO | 16/436542 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/12 (20130101) A61K 9/0019 (20130101) A61K 9/2027 (20130101) A61K 9/2054 (20130101) A61K 9/2059 (20130101) A61K 9/4866 (20130101) A61K 31/437 (20130101) A61K 31/437 (20130101) A61K 31/495 (20130101) A61K 31/495 (20130101) A61K 31/506 (20130101) Original (OR) Class A61K 31/506 (20130101) A61K 31/519 (20130101) A61K 31/519 (20130101) A61K 31/4184 (20130101) A61K 31/4184 (20130101) A61K 31/4439 (20130101) A61K 31/4439 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
11129831 — Identification of agents displaying functional activation of dopamine D2 and D4 receptors
| US 11129831 | Ablordeppey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Florida A and M University (Tallahassee, Florida) |
| ASSIGNEE(S) | Florida A and M University (Tallahassee, Florida) |
| INVENTOR(S) | Seth Y. Ablordeppey (Tallahassee, Florida); Xue Y. Zhu (Tallahassee, Florida) |
| ABSTRACT | A method of treating psychosis, and the underlying antipsychotic formulation. The method includes administering a therapeutically effective amount of synthetic agents that selectively recruit β-arrestin to D2 receptors and have little-to-no binding to culprit receptors associated with weight gain and Type II diabetes. The synthetic agents can include SYA16263 and SYA16264, and/or derivatives or analogs thereof. The 1-(pyridin-2-yl)piperazine moiety was found to play a significant role in recruiting β-arrestin to D2 receptors. In other embodiments, the current invention relates to synthetic agents that are selective of D4 receptors for treatment of psychosis and erectile dysfunction. The synthetic agents can include SYA27287 and/or derivatives or analogs thereof. In all embodiments, extrapyramidal side effects are eliminated or minimized. |
| FILED | Friday, August 09, 2019 |
| APPL NO | 16/537193 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/496 (20130101) A61K 31/506 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/18 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11129835 | Lu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); The United States of America, as represented by the Secretary, Department of Health and Human Services Office of Technology Transfer, National Institutes of Health (Bethesda, Maryland) |
| INVENTOR(S) | Kun Ping Lu (Newton, Massachusetts); Matthew Brian Boxer (Rockville, Maryland); Mindy Irene Emily Davis (Rockville, Maryland); Rajan Pragani (Rockville, Maryland); Min Shen (Rockville, Maryland); Anton Momtchilov Simeonov (Rockville, Maryland); Shuo Wei (Chestnut Hill, Massachusetts); Xiao Zhen Zhou (Newton, Massachusetts) |
| ABSTRACT | The invention features compositions and methods for inhibiting the Pin1 protein, and the treatment of disorders characterized by elevated Pin1 levels. |
| FILED | Friday, September 13, 2019 |
| APPL NO | 16/570470 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/185 (20130101) A61K 31/341 (20130101) A61K 31/357 (20130101) A61K 31/365 (20130101) A61K 31/381 (20130101) A61K 31/382 (20130101) A61K 31/402 (20130101) A61K 31/404 (20130101) A61K 31/405 (20130101) A61K 31/427 (20130101) A61K 31/428 (20130101) A61K 31/473 (20130101) A61K 31/473 (20130101) A61K 31/496 (20130101) A61K 31/4025 (20130101) A61K 31/4245 (20130101) A61K 31/4704 (20130101) A61K 31/5377 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11129844 | Freier et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ionis Pharmaceuticals, Inc. (Carlsbad, California); Baylor College of Medicine (Houston, Texas) |
| ASSIGNEE(S) | Ionis Pharmaceuticals, Inc. (Carlsbad, California); Baylor College of Medicine (Houston, Texas) |
| INVENTOR(S) | Susan M. Freier (San Diego, California); Huda Y. Zoghbi (Houston, Texas); Ezequiel Sztainberg (Houston, Texas) |
| ABSTRACT | Disclosed herein are compounds and methods for decreasing MECP2 mRNA and protein expression. Such compounds and methods are useful to treat, prevent, or ameliorate MECP2 associated disorders and syndromes. Such MECP2 associated disorders include MECP2 duplication syndrome. |
| FILED | Thursday, August 08, 2019 |
| APPL NO | 16/535888 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/712 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/22 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11129845 | Lu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Zheng-Rong Lu (Cleveland, Ohio); Anthony Malamas (Cleveland, Ohio); Maneesh Gujrati (Cleveland, Ohio); Da Sun (Cleveland, Ohio) |
| ABSTRACT | A compound comprising formula (I): wherein R1 is an akylamino group or a group containing at least one aromatic group; R2 and R3 are independently an aliphatic group or hydrophobic group; R4 and R5 are independently H, a substituted or unsubstituted akyl group, an akenyl group, an acyl group, an aromatic group, polymer, a targeting group, or a detectable moiety; a, b, c, and d are independently an integer from 1 to 10; and pharmaceutically acceptable salts thereof. |
| FILED | Thursday, June 18, 2015 |
| APPL NO | 14/743298 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Original (OR) Class A61K 48/0033 (20130101) Peptides C07K 5/0606 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2320/31 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11129846 | Ray et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Anuradha Ray (Pittsburgh, Pennsylvania); Prabir Ray (Pittsburgh, Pennsylvania); Timothy B. Oriss (Pittsburgh, Pennsylvania); Sally Ellen Wenzel (Pittsburgh, Pennsylvania) |
| ABSTRACT | Methods are provided for treating corticosteroid-resistant asthma in a patient, comprising decreasing Interferon Regulatory Factor 5 (IRF5) activity in the patient. Antisense or RNA interference reagents and methods can be used to decrease IRF5 activity in the patient. |
| FILED | Tuesday, August 13, 2019 |
| APPL NO | 16/539383 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/573 (20130101) A61K 31/713 (20130101) Original (OR) Class A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11129854 | Frank et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia); Schepens Eye Research Institute (Boston, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Schepens Eye Research Institute (Boston, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Markus H. Frank (Cambridge, Massachusetts); Natasha Y. Frank (Cambridge, Massachusetts); Bruce Ksander (Boston, Massachusetts); Paraskevi Evi Kolovou (Boston, Massachusetts) |
| ABSTRACT | Various aspects and embodiments of the present invention are directed to methods of treating a subject having an ocular condition, methods of isolating ocular stem cells, methods of selecting and/or producing ocular grafts for transplantation, and methods of promoting ocular cell regeneration as well as to grafts and preparations containing isolated ocular stem cells characterized by the expression of ABCB5 on their cell surface. |
| FILED | Monday, October 30, 2017 |
| APPL NO | 15/796920 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0051 (20130101) A61K 35/30 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/3834 (20130101) A61L 27/3839 (20130101) A61L 2430/16 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0621 (20130101) C12N 5/0623 (20130101) C12N 5/0668 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11129858 | Hsiao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Elaine Hsiao (Los Angeles, California); Jessica Yano (Los Angeles, California); Helen Vuong (Los Angeles, California); Christine Olson (Los Angeles, California) |
| ABSTRACT | Provided herein are methods and compositions related to treating or preventing seizures. In some aspects, provided herein are methods of treating or preventing seizures in a subject by administering to the subject a composition comprising Parabacteroides and Akkermansia bacteria. |
| FILED | Wednesday, December 20, 2017 |
| APPL NO | 16/471460 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/30 (20160801) A23L 33/135 (20160801) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0031 (20130101) A61K 9/0053 (20130101) A61K 35/74 (20130101) Original (OR) Class A61K 39/0216 (20130101) A61K 2035/115 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11129870 | McNamara et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | DUKE UNIVERSITY (Durhman, North Carolina) |
| INVENTOR(S) | James O. McNamara (Chapel Hill, North Carolina); Xiao-Ping He (Cary, North Carolina); Yangzhong Huang (Chapel Hill, North Carolina); Bin Gu (Durham, North Carolina) |
| ABSTRACT | The invention provides pharmaceutical compositions and methods of use thereof for preventing or ameliorating disorders of the nervous system. More specifically, the invention provides pharmaceutical compositions, including phosphopeptides that when administered disrupt the physical interaction of TrkB with its signaling effector, phospholipase Cγ1 (PLCγ1). The invention further provides method of treatment comprising administering phosphopeptides that uncouple TrkB from PLCγ1 in order to prevent and/or ameliorate nervous system disorders such as epilepsy, anxiety, and seizures. |
| FILED | Monday, June 10, 2019 |
| APPL NO | 16/436867 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) A61K 31/7105 (20130101) A61K 38/04 (20130101) A61K 38/04 (20130101) A61K 38/16 (20130101) Original (OR) Class A61K 38/16 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/2863 (20130101) C07K 2317/33 (20130101) C07K 2317/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11129871 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ying Chen (St. Louis, Missouri); Fumihiko Urano (St. Louis, Missouri); Yeawon Kim (St. Louis, Missouri); Sun-Ji Park (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Ying Chen (St. Louis, Missouri); Fumihiko Urano (St. Louis, Missouri); Yeawon Kim (St. Louis, Missouri); Sun-Ji Park (St. Louis, Missouri) |
| ABSTRACT | Among the various aspects of the present disclosure is the provision of methods and compositions to treat or prevent an endoplasmic reticulum (ER) stress-mediated kidney disease in a subject, the method comprising administering to the subject a pharmaceutical composition comprising a therapeutically effective amount of an ER calcium channel stabilizing agent or an ER stress modulating agent (e.g., mesencephalic astrocyte-derived neurotrophic factor (MANF), compound K201). |
| FILED | Wednesday, June 19, 2019 |
| APPL NO | 16/446073 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/554 (20130101) A61K 38/1709 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 13/12 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11129879 | Spiegelman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Bruce M. Spiegelman (Waban, Massachusetts); Christiane D. Wrann (Medford, Massachusetts) |
| ABSTRACT | The invention provides methods for identifying, assessing, preventing, and treating neurological disorders and diseases using Fndc5 and modulators of Fndc5 expression or activity. |
| FILED | Monday, March 25, 2019 |
| APPL NO | 16/362770 |
| ART UNIT | 1699 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/39 (20130101) Original (OR) Class A61K 38/1709 (20130101) A61K 48/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5023 (20130101) G01N 33/5058 (20130101) G01N 33/6896 (20130101) G01N 2333/78 (20130101) G01N 2800/28 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11129881 | Shea et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Lonnie D. Shea (Evanston, Illinois); Stephen D. Miller (Evanston, Illinois); Jonathan Woon Teck Yap (Evanston, Illinois); Daniel R. Getts (Northbrook, Illinois); Derrick McCarthy (Evanston, Illinois) |
| ABSTRACT | The present invention provides compositions comprising peptide-coupled biodegradable poly(lactide-co-glycolide) (PLG) particles. In particular, PLG particles are surface-functionalized to allow for coupling of peptide molecules to the surface of the particles (e.g., for use in eliciting induction of immunological tolerance). |
| FILED | Monday, April 13, 2020 |
| APPL NO | 16/847450 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/19 (20130101) A61K 9/1647 (20130101) A61K 9/5153 (20130101) A61K 39/00 (20130101) A61K 39/0008 (20130101) Original (OR) Class A61K 47/58 (20170801) A61K 47/6911 (20170801) A61K 47/6935 (20170801) A61K 47/6937 (20170801) A61K 2039/577 (20130101) A61K 2039/622 (20130101) A61K 2039/55555 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11129889 | Ruprecht et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Louisiana at Lafayette (Lafayette, Louisiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ruth M. Ruprecht (Lafayette, Louisiana); Hemant K. Vyas (San Antonio, Texas) |
| ABSTRACT | Provided herein are recombinant nucleic acid sequences derived from the C-terminal domain of the HIV-1 gp41 protein, and more specifically compositions and methods for using these epitopes to develop vaccine protection against HIV. Also provided here are monoclonal antibodies that specifically bind to these recombinant nucleic acid sequences derived from the C-terminal domain of the HIV-1 gp41 protein. |
| FILED | Tuesday, November 07, 2017 |
| APPL NO | 16/348097 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) Original (OR) Class A61K 2039/55566 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) A61P 31/18 (20180101) Peptides C07K 14/005 (20130101) C07K 16/1063 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/15034 (20130101) C12N 2740/16071 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) C12N 2740/16171 (20130101) C12N 2740/16334 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11129891 | Shenk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Thomas Shenk (Princeton, New Jersey); Dai Wang (Blue Bell, Pennsylvania) |
| ABSTRACT | Immunogenic compositions and prophylactic or therapeutic vaccines for use in protecting and treating against human cytomegalovirus (CMV) are disclosed. Subunit vaccines comprising a human CMV protein complex comprising pUL128 or pUL130, and nucleic acid vaccines comprising at least one nucleic acid encoding a CMV protein complex comprising pUL128 or pUL130 are described. Also disclosed are therapeutic antibodies reactive against a CMV protein complex comprising pUL128 or pUL130, as well as methods for screening compounds that inhibit CMV infection of epithelial and endothelial cells, methods for immunizing a subject against CMV infection, methods for determining the capability of neutralizing antibodies to inhibit CMV infection of cell types other than fibroblasts, and methods of diminishing an CMV infection. |
| FILED | Thursday, April 11, 2019 |
| APPL NO | 16/382125 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/245 (20130101) Original (OR) Class A61K 2039/505 (20130101) Peptides C07K 14/005 (20130101) C07K 16/085 (20130101) C07K 16/088 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/16122 (20130101) C12N 2710/16134 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/025 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2500/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11129902 | Alhamadsheh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mamoun M Alhamadsheh (Stockton, California) |
| ASSIGNEE(S) | Mamoun M. Alhamadsheh (Stockton, California) |
| INVENTOR(S) | Mamoun M. Alhamadsheh (Stockton, California); Miki S. Park (Stockton, California); William K. Chan (Elk Grove, California); Xiaoling Li (Dublin, California); Sravan C. Penchala (Stockton, California); Mark R. Miller (Stockton, California) |
| ABSTRACT | The teachings provide methods of delivering active agents that are conjugated with delivery systems that increase the half-life, and reduce the immunogenicity, of the active agents. Delivery systems and methods of making and using the delivery systems are also provided. The delivery systems have (i) a ligand that is selective for an endogeneous plasma protein in the serum of a subject; and, (ii) a linker configured for operatively attaching the ligand covalently to an active agent to increase the half-life of the active agent in the serum. |
| FILED | Wednesday, August 12, 2020 |
| APPL NO | 16/991404 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/4745 (20130101) A61K 38/00 (20130101) A61K 47/64 (20170801) Original (OR) Class A61K 47/545 (20170801) A61K 49/0052 (20130101) Heterocyclic Compounds C07D 231/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11129905 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sanofi (Paris, France) |
| ASSIGNEE(S) | SANOFI (Paris, France) |
| INVENTOR(S) | Zhi-Yong Yang (Bridgewater, New Jersey); Gary J. Nabel (Bridgewater, New Jersey); Ling Xu (Bridgewater, New Jersey); Jochen Beninga (Frankfurt am Main, Germany); Jochen Kruip (Erzhausen, Germany); Ercole Rao (Morfelden-Walldorf, Germany); Wulf Dirk Leuschner (Frankfurt am Main, Germany); Christian Beil (Frankfurt am Main, Germany); Christian Lange (Frankfurt am Main, Germany) |
| ABSTRACT | Provided herein are bivalent, bispecific binding proteins that specifically bind to two different HIV-1 Env protein epitopes. |
| FILED | Monday, October 21, 2019 |
| APPL NO | 16/659426 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 47/6881 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) Peptides C07K 16/468 (20130101) C07K 16/1063 (20130101) C07K 2317/31 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) C07K 2317/565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11129906 | Bermudes |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David Gordon Bermudes (Woodland Hills, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Gordon Bermudes (Woodland Hills, California) |
| ABSTRACT | Bacteria with tumor-targeting capability express, surface displayed, secreted and/or released modified chimeric therapeutic proteins with enhanced therapeutic activity against a neoplastic tissue including solid tumors, lymphomas and leukemias. The bacteria may be attenuated, non-pathogenic, low pathogenic or a probiotic. The chimeric proteins may be protease sensitive and may optionally be further accompanied by co-expression of a secreted protease inhibitor as a separate molecule or as a fusion. |
| FILED | Thursday, December 07, 2017 |
| APPL NO | 15/835093 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/162 (20130101) A61K 38/164 (20130101) A61K 45/06 (20130101) A61K 48/005 (20130101) Original (OR) Class Peptides C07K 14/005 (20130101) C07K 14/255 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/70 (20130101) C12N 15/74 (20130101) C12N 2710/00022 (20130101) C12N 2710/00033 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11129911 | Dharmakumar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| ASSIGNEE(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| INVENTOR(S) | Rohan Dharmakumar (Moorpark, California); Debiao Li (San Marino, California); Sotirios A. Tsaftaris (Lucca, Italy) |
| ABSTRACT | There are provided methods for diagnosing coronary heart disease in a subject in need thereof comprising administering an admixture comprising CO2 to a subject to reach a predetermined PaCO2 in the subject to induce hyperemia, monitoring vascular reactivity in the subject and diagnosing the presence or absence of coronary heart disease in the subject, wherein decreased vascular reactivity in the subject compared to a control subject is indicative of coronary heart disease. There are also provided methods for increasing sensitivity and specificity of BOLD MRI. |
| FILED | Friday, March 02, 2018 |
| APPL NO | 15/910718 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7076 (20130101) A61K 33/00 (20130101) A61K 49/08 (20130101) Original (OR) Class A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11129921 | Kaplan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
| ASSIGNEE(S) | Trustees of Tufts College (Medford, Massachusetts) |
| INVENTOR(S) | David L. Kaplan (Concord, Massachusetts); Ung-Jin Kim (Daejeon, South Korea); Jaehyung Park (Decatur, Georgia); Hyoung-Joon Jin (Seoul, South Korea) |
| ABSTRACT | The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels. |
| FILED | Wednesday, May 08, 2019 |
| APPL NO | 16/406538 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/38 (20130101) A61L 27/52 (20130101) A61L 27/56 (20130101) A61L 27/227 (20130101) Original (OR) Class A61L 27/3604 (20130101) A61L 2430/02 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 39/003 (20130101) B29C 39/203 (20130101) B29C 55/005 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 7/01 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2089/00 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2007/00 (20130101) B29L 2009/00 (20130101) Peptides C07K 14/43536 (20130101) C07K 14/43586 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/07 (20130101) C08J 3/075 (20130101) C08J 5/18 (20130101) C08J 9/26 (20130101) C08J 9/28 (20130101) C08J 9/0061 (20130101) C08J 2201/0444 (20130101) C08J 2201/0504 (20130101) C08J 2205/022 (20130101) C08J 2389/00 (20130101) Compositions of Macromolecular Compounds C08L 89/00 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0007 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 4/02 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/249921 (20150401) Y10T 442/10 (20150401) Y10T 442/60 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11129938 | Rosinko et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Beta Bionics, Inc. (Concord, Massachusetts) |
| ASSIGNEE(S) | Beta Bionics, Inc. (Concord, Massachusetts) |
| INVENTOR(S) | Michael J. Rosinko (Anaheim, California); Edward R. Damiano (Acton, Massachusetts); David Chi-Wai Lim (Irvine, California); Firas H. El-Khatib (Allston, Massachusetts); Himanshu Patel (Rancho Santa Margarita, California); John R. Costik (Livonia, New York); Justin P. Brown (Tustin, California); Bryan Dale Knodel (Flagstaff, Arizona) |
| ABSTRACT | Systems and methods are disclosed herein for updating an application controlling an ambulatory medical device such that application updates can be identified, downloaded and installed without interrupting therapy provided by the ambulatory medical device to a subject. The ambulatory medical device may receive an indication that an update to an application executing on the ambulatory insulin pump is available, establish a communication connection to a host computing system configured to host the application update, and download the application update. The disclosed systems and methods can determine an execution time of an installation and install the downloaded application update without interrupting therapy provided by the ambulatory medical device to the subject. |
| FILED | Friday, October 02, 2020 |
| APPL NO | 17/062356 |
| ART UNIT | 2192 — Interprocess Communication and Software Development |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/14532 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/142 (20130101) A61M 5/172 (20130101) Original (OR) Class A61M 5/1723 (20130101) A61M 5/14244 (20130101) A61M 5/14248 (20130101) A61M 5/16831 (20130101) A61M 2005/1726 (20130101) A61M 2005/14208 (20130101) A61M 2205/18 (20130101) A61M 2205/50 (20130101) A61M 2205/52 (20130101) A61M 2205/502 (20130101) A61M 2205/505 (20130101) A61M 2205/581 (20130101) A61M 2205/582 (20130101) A61M 2205/583 (20130101) A61M 2205/609 (20130101) A61M 2205/3327 (20130101) A61M 2205/3546 (20130101) A61M 2205/3553 (20130101) A61M 2205/3584 (20130101) A61M 2205/3592 (20130101) A61M 2230/201 (20130101) Electric Digital Data Processing G06F 3/04847 (20130101) G06F 3/04883 (20130101) G06F 8/61 (20130101) G06F 8/65 (20130101) G06F 8/656 (20180201) G06F 21/31 (20130101) G06F 21/84 (20130101) G06F 21/305 (20130101) G06F 21/6245 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/18 (20130101) G08B 21/0453 (20130101) G08B 25/00 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 20/17 (20180101) G16H 40/00 (20180101) G16H 40/40 (20180101) G16H 40/60 (20180101) G16H 40/67 (20180101) G16H 50/30 (20180101) G16H 80/00 (20180101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/30 (20130101) H04L 9/088 (20130101) H04L 63/101 (20130101) H04L 67/34 (20130101) Wireless Communication Networks H04W 76/10 (20180201) H04W 76/14 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11129983 | Lo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Yi-Kai Lo (Los Angeles, California); Wentai Liu (Los Angeles, California); Victor R. Edgerton (Los Angeles, California); Chih-Wei Chang (Los Angeles, California) |
| ABSTRACT | A wireless implant and associated system for motor function recovery after spinal cord injury, and more particularly a multi-channel wireless implant with small package size. The wireless implant can further be used in various medical applications, such as retinal prostheses, gastrointestinal implant, vagus nerve stimulation, and cortical neuromodulation. The system also includes a method and its implementation to acquire the impedance model of the electrode-tissue interface of the implant. |
| FILED | Tuesday, July 24, 2018 |
| APPL NO | 16/043414 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/08 (20130101) A61N 1/0551 (20130101) A61N 1/3787 (20130101) A61N 1/36003 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11129984 | Greenberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
| ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
| INVENTOR(S) | Robert Jay Greenberg (Los Angeles, California); Kelly Hobart McClure (Simi Valley, California); James S. Little (Arvada, Colorado); Rongqing Dai (Valencia, California); Arup Roy (Los Angeles, California); Richard Agustin Castro (Santa Monica, California); John Reinhold (Tarzana, California); Kea-Tiong Tang (Hsinchu, Taiwan); Sumit Yadav (Lake Forest, California); Chunhong Zhou (San Diego, California); David Daomin Zhou (Valencia, California); Pishoy Maksy (Newport Beach, California) |
| ABSTRACT | In electrically stimulating neural tissue it is important to prevent over stimulation and unbalanced stimulation, which would cause damage to the neural tissue, the electrode, or both. It is critical that neural tissue is not subjected to any direct current or alternating current above a safe threshold. Further, it is important to identify defective electrodes, as continued use may result in neural damage and further electrode damage. The present invention presents system and stimulator control mechanisms to prevent damage to neural tissue. |
| FILED | Thursday, July 18, 2019 |
| APPL NO | 16/516058 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/00 (20130101) A61N 1/08 (20130101) A61N 1/0543 (20130101) A61N 1/0551 (20130101) A61N 1/3603 (20170801) A61N 1/36046 (20130101) Original (OR) Class A61N 1/36142 (20130101) A61N 1/36185 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130679 | Moghaddam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Seyyed Pouya Hadipour Moghaddam (Salt Lake City, Utah); Hamidreza Ghandehari (Salt Lake City, Utah) |
| ABSTRACT | The disclosure extends to biodegradable hollow nanoparticles, and systems, methods, devices, and processes for producing the same. The disclosure includes a method of preparing a hollow mesoporous nanoparticle by providing a plurality of silica core particles. Each of the plurality of silica core particles comprises a diameter within a range of about 600 nanometers to about 30 nanometers. The method further includes synthesizing a mesoporous silica shell around the plurality of silica core particles forming a plurality of mesoporous coated silica core particles. Further, the method provides for etching the plurality of mesoporous coated silica core particles with an aqueous solution of sodium carbonate and water to remove the silica core particle from the plurality of mesoporous coated silica core particles forming a plurality of hollow mesoporous particles. The method also includes diffusing a payload into the plurality of hollow mesoporous particles in an aqueous solution. |
| FILED | Wednesday, March 06, 2019 |
| APPL NO | 16/294872 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 33/18 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/34 (20130101) C01P 2004/64 (20130101) C01P 2006/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130736 | David et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF KANSAS (Lawrence, Kansas) |
| ASSIGNEE(S) | University of Kansas (Lawrence, Kansas) |
| INVENTOR(S) | Sunil A. David (Lawrence, Kansas); Mallesh Beesu (Lawrence, Kansas); Giuseppe Caruso (Lawrence, Kansas); Alex Salyer (Marion, Ohio) |
| ABSTRACT | The disclosure provides human toll-like receptor modulators of general Formula (II), wherein R1, R2, R3, R4, R5, R6, R7, R8 are defined herein. |
| FILED | Friday, August 19, 2016 |
| APPL NO | 15/754193 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/02 (20180101) Heterocyclic Compounds C07D 215/38 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130737 | Tabakoff |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LOHOCLA RESEARCH CORPORATION (Evanston, Illinois) |
| ASSIGNEE(S) | LOHOCLA RESEARCH CORPORATION (Evanston, Illinois) |
| INVENTOR(S) | Boris Tabakoff (Elizabeth, Illinois) |
| ABSTRACT | Aminoquinoline compounds useful for treating chronic pain, addiction, and other conditions are provided. The aminoquinoline compound is represented by Formula (I): in which the substituents thereof are defined as set forth in the specification. |
| FILED | Monday, October 07, 2019 |
| APPL NO | 16/594333 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/485 (20130101) A61K 31/485 (20130101) A61K 31/616 (20130101) A61K 31/616 (20130101) A61K 31/4706 (20130101) A61K 31/4706 (20130101) A61K 33/24 (20130101) A61K 33/243 (20190101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 215/46 (20130101) C07D 215/48 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130743 | Dockendorff et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Marquette University (Milwaukee, Wisconsin) |
| ASSIGNEE(S) | Marquette University (Milwaukee, Wisconsin) |
| INVENTOR(S) | Christopher Dockendorff (Milwaukee, Wisconsin); Disha M. Gandhi (Carrboro, North Carolina); Ricardo Rosas, Jr. (Milwaukee, Wisconsin) |
| ABSTRACT | The present invention provides novel compounds with increased plasma stability that modulate PAR1 signaling, and methods of using them. The present invention provides methods of using the novel PAR1 modulators for the treatment of a number of disorders, including, inflammation, thrombosis, kidney disease, sepsis, stroke, as well as proliferation-related diseases. Furthermore, the PAR1 modulators of the present invention provide cytoprotection for certain cells and tissues, for example, in coronary blood vessels and tissues after a heart attack. |
| FILED | Monday, March 23, 2020 |
| APPL NO | 16/827147 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) Acyclic or Carbocyclic Compounds C07C 233/66 (20130101) C07C 233/80 (20130101) Heterocyclic Compounds C07D 233/90 (20130101) C07D 263/34 (20130101) C07D 277/587 (20130101) C07D 307/68 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130744 | Piazza et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ADT Pharmaceuticals, LLC (Orange Beach, Alabama) |
| ASSIGNEE(S) | ADT Pharmaceuticals, LLC (Orange Beach, Alabama) |
| INVENTOR(S) | Gary A. Piazza (Daphne, Alabama); Xi Chen (Hoover, Alabama); Adam B. Keeton (Gardendale, Alabama); Michael R. Boyd (Orange Beach, Alabama) |
| ABSTRACT | Disclosed are compounds, for example, compounds of formula I, wherein R, R0, R1-R8, n, X, Y, Y′, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer. |
| FILED | Monday, March 30, 2020 |
| APPL NO | 16/834348 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/36 (20130101) A61K 31/36 (20130101) A61K 31/40 (20130101) A61K 31/40 (20130101) A61K 31/44 (20130101) A61K 31/44 (20130101) A61K 31/341 (20130101) A61K 31/341 (20130101) A61K 31/401 (20130101) A61K 31/445 (20130101) A61K 31/445 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Acyclic or Carbocyclic Compounds C07C 233/58 (20130101) C07C 235/32 (20130101) C07C 237/20 (20130101) C07C 2601/02 (20170501) C07C 2602/08 (20170501) Heterocyclic Compounds C07D 207/14 (20130101) C07D 207/337 (20130101) C07D 211/56 (20130101) C07D 213/24 (20130101) C07D 213/75 (20130101) C07D 235/30 (20130101) C07D 307/38 (20130101) C07D 307/52 (20130101) C07D 307/54 (20130101) C07D 317/64 (20130101) Original (OR) Class C07D 405/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130772 | Schunck et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MAX-DELBRUECK-CENTRUM FUER MOLEKULARE MEDIZIN (Berlin, Germany); BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | MAX-DELBRUECK-CENTRUM FUER MOLEKULARE MEDIZIN (, None); BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (, None) |
| INVENTOR(S) | Wolf-Hagen Schunck (Berlin, Germany); Dominik Mueller (Berlin, Germany); Robert Fischer (Berlin, Germany); Gerd Wallukat (Berlin, Germany); Anne Konkel (Berlin, Germany); John Russell Falck (Dallas, Texas) |
| ABSTRACT | The present invention relates to compounds according to general formula (I) which are analogues of epoxymetabolites produced by cytochrome P450 (CYP) enzymes from omega-3 (n-3) polyunsaturated fatty acids (PUFAs). The present invention further relates to compositions containing one or more of these compounds and to the use of these compounds or compositions for the treatment or prevention of conditions and diseases associated with inflammation, proliferation, hypertension, coagulation, immune function, pathologic angiogenesis, heart failure and cardiac arrhythmias. |
| FILED | Wednesday, January 21, 2015 |
| APPL NO | 15/113139 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 309/21 (20130101) C07C 311/51 (20130101) C07C 323/41 (20130101) Heterocyclic Compounds C07D 277/82 (20130101) C07D 291/04 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/3826 (20130101) Original (OR) Class C07F 9/3882 (20130101) C07F 9/4015 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130779 | Evans et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Salk Institute for Biological Studies (La Jolla, California) |
| ASSIGNEE(S) | The Salk Institute for Biological Studies (La Jolla, California) |
| INVENTOR(S) | Ronald M. Evans (La Jolla, California); Michael Downes (La Jolla, California) |
| ABSTRACT | Provided herein are deuterated compounds and compositions useful in increasing PPARδ activity. The compounds have a formula where L5 comprises at least one deuterium. Exemplary species include The compounds and compositions provided herein are useful for the treatment of PPARδ related diseases (e.g., muscular diseases, vascular disease, demyelinating disease, and metabolic diseases). |
| FILED | Tuesday, December 17, 2019 |
| APPL NO | 16/717830 |
| ART UNIT | 1699 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 233/73 (20130101) C07C 233/75 (20130101) C07C 233/87 (20130101) C07C 235/42 (20130101) C07C 235/48 (20130101) C07C 235/84 (20130101) C07C 237/32 (20130101) C07C 255/57 (20130101) C07C 259/06 (20130101) C07C 317/44 (20130101) C07C 2601/02 (20170501) C07C 2601/08 (20170501) Heterocyclic Compounds C07D 205/04 (20130101) C07D 209/34 (20130101) C07D 213/40 (20130101) C07D 213/56 (20130101) C07D 213/64 (20130101) C07D 231/12 (20130101) C07D 271/12 (20130101) C07D 295/13 (20130101) C07D 295/155 (20130101) C07D 305/06 (20130101) C07D 307/54 (20130101) C07D 307/68 (20130101) C07D 307/81 (20130101) C07D 307/83 (20130101) C07D 309/04 (20130101) C07D 309/06 (20130101) C07D 333/24 (20130101) C07D 333/38 (20130101) C07D 401/04 (20130101) C07D 401/12 (20130101) C07D 405/04 (20130101) C07D 405/10 (20130101) C07D 405/12 (20130101) C07D 407/12 (20130101) C07D 409/12 (20130101) C07D 413/04 (20130101) C07D 413/12 (20130101) C07D 417/04 (20130101) C07D 417/10 (20130101) C07D 417/12 (20130101) Peptides C07K 5/06026 (20130101) C07K 5/06034 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130785 | Kwong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Peter D. Kwong (Washington, District of Columbia); Barney S. Graham (Rockville, Maryland); Jason S. McLellan (Austin, Texas); Jeffrey Boyington (Clarksburg, Maryland); Lei Chen (Rockville, Maryland); Man Chen (Bethesda, Maryland); Gwo-Yu Chuang (Rockville, Maryland); Ivelin Stefanov Georgiev (Nashville, Tennessee); Jason Gorman (Washington, District of Columbia); Michael Gordon Joyce (Washington, District of Columbia); Masaru Kanekiyo (Chevy Chase, Maryland); Gilad Ofek (Gaithersburg, Maryland); Marie Pancera (Seattle, Washington); Mallika Sastry (Rockville, Maryland); Cinque Soto (Rockville, Maryland); Sanjay Srivatsan (Lilburn, Georgia); Guillaume Stewart-Jones (Bethesda, Maryland); Yongping Yang (Potomac, Maryland); Baoshan Zhang (Bethesda, Maryland); Tongqing Zhou (Boyds, Maryland) |
| ABSTRACT | Disclosed are Respiratory Syncytial Virus (RSV) antigens including a recombinant RSV F protein stabilized in a prefusion conformation. Also disclosed are nucleic acids encoding the antigens and methods of producing the antigens. Methods for generating an immune response in a subject are also disclosed. In some embodiments, the method is a method for treating or preventing a RSV infection in a subject by administering a therapeutically effective amount of the antigen to the subject. |
| FILED | Monday, July 02, 2018 |
| APPL NO | 16/025858 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/155 (20130101) A61K 2039/53 (20130101) A61K 2039/543 (20130101) A61K 2039/5252 (20130101) A61K 2039/5254 (20130101) A61K 2039/55505 (20130101) A61K 2039/55561 (20130101) A61K 2039/55566 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 2319/21 (20130101) C07K 2319/22 (20130101) C07K 2319/50 (20130101) C07K 2319/70 (20130101) C07K 2319/735 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/10343 (20130101) C12N 2760/18522 (20130101) C12N 2760/18534 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130788 | Hagen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Andrew R. Hagen (Oakland, California); Cheryl A. Kerfeld (Walnut Creek, California); Nancy B. Sloan (Berkeley, California); Markus Sutter (Oakland, California); Bryan H. Ferlez (Haslett, Michigan) |
| ABSTRACT | The present invention provides for a fusion protein comprising (1) a bacterial microcompartment (BMC) shell protein comprising one or more subunit, and (2) a first component of a specific-binding pair, operably linked to the BMC shell protein such that the first component faces (i) a lumen (inside) side, or (ii) outside of a BMC shell formed incorporating the fusion protein and the fusion protein does not disrupt or prevent the folding of the BMC shell protein or the ability of the BMC shell protein to integrate with other BMC shell proteins into a BMC shell; wherein the first component is capable of forming a stable or irreversible interaction with a second component of the specific-binding pair. |
| FILED | Tuesday, May 14, 2019 |
| APPL NO | 16/412133 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Separation B01D 15/363 (20130101) B01D 15/3804 (20130101) Peptides C07K 1/22 (20130101) C07K 14/195 (20130101) Original (OR) Class C07K 14/315 (20130101) C07K 2319/70 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130798 | Ley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (La Jolla, California) |
| ASSIGNEE(S) | LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (La Jolla, California) |
| INVENTOR(S) | Klaus Ley (La Jolla, California); Alessandro Sette (La Jolla, California) |
| ABSTRACT | Provided herein are composition comprising novel epitopes of ApoB100, as well as sub-sequences, portions and modifications thereof, and uses thereof for treating adverse cardiovascular events, cardiovascular disease, atherosclerosis and certain liver disorders. |
| FILED | Wednesday, May 18, 2016 |
| APPL NO | 15/574784 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/10 (20130101) A61K 38/1709 (20130101) A61K 39/0005 (20130101) A61K 45/06 (20130101) A61K 2039/57 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/16 (20180101) A61P 9/10 (20180101) Peptides C07K 7/08 (20130101) C07K 14/775 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130801 | Medof et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | M. Edward Medof (Pepper Pike, Ohio); Michael G. Strainic (Westlake, Ohio); Elliot Pohlmann (Roanoke, Virginia); Ming-Shih Hwang (Danbury, Connecticut) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | M. Edward Medof (Pepper Pike, Ohio); Michael G. Strainic (Westlake, Ohio); Elliot Pohlmann (Roanoke, Virginia); Ming-Shih Hwang (Danbury, Connecticut) |
| ABSTRACT | A method of modulating growth factor responses of cells expressing C3a receptor (C3aR) and C5a receptor (C5aR) and at least one growth factor receptor includes administering to the cells at least one agent that modulates C3aR and/or C5aR signaling of the cells. |
| FILED | Friday, January 13, 2012 |
| APPL NO | 13/350402 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/06 (20130101) A61K 38/08 (20130101) A61K 38/57 (20130101) A61K 38/58 (20130101) A61K 45/06 (20130101) A61K 2039/507 (20130101) Peptides C07K 16/18 (20130101) Original (OR) Class C07K 16/28 (20130101) C07K 16/248 (20130101) C07K 2317/32 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) G01N 2500/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130813 | Weissman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Irving L. Weissman (Stanford, California); Stephen Willingham (Mountain View, California); Doris Po Yi Ho (Daly City, California); Piero D. Dalerba (New York, New York); Kelly Marie McKenna (Palo Alto, California); Jens-Peter Volkmer (Menlo Park, California) |
| ABSTRACT | Methods are provided for targeting cells for depletion, including without limitation cancer cells, in a regimen comprising contacting the targeted cells with a combination of agents, including (i) an agent that blockades CD47 activity; and (ii) an antibody that specifically binds to EGFR. In some embodiments the cancer cells have a mutated form of one or more of KRAS, NRAS or BRAF. The level of depletion of the targeted cell is enhanced relative to a regimen in which a single agent is used; and the effect may be synergistic relative to a regimen in which a single agent is used. |
| FILED | Tuesday, May 14, 2019 |
| APPL NO | 16/411547 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39558 (20130101) A61K 2039/507 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2803 (20130101) C07K 16/2839 (20130101) C07K 16/2863 (20130101) Original (OR) Class C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130821 | Rittenhouse-Olson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Foundation for The State University of New York (Amherst, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Amherst, New York) |
| INVENTOR(S) | Kate Rittenhouse-Olson (Williamsville, New York); Julia Abdullah (Amherst, New York); Jing Ying Eng (Selangor, Malaysia); Stephen T. Koury (Williamsville, New York) |
| ABSTRACT | Provided are humanized monoclonal antibodies (mAbs) or fragments thereof that bind with specificity to the Thomsen-Friedenreich (TF) human tumor antigen. Three distinct variable heavy and three variable light chains are provided, and can be combined to make a total of twenty-five distinct heavy and light chain combinations. Methods of using the mAbs and fragments thereof for cancer therapy and diagnostic imaging are provided, as are methods for making the mAbs and fragments thereof. In vitro cell cultures that express the mAbs and fragments thereof, and kits are also provided. |
| FILED | Thursday, May 10, 2018 |
| APPL NO | 15/976500 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/44 (20130101) C07K 16/2896 (20130101) C07K 16/3076 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/33 (20130101) C07K 2317/73 (20130101) C07K 2317/77 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/567 (20130101) C07K 2317/732 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130937 | Norris et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Steven J. Norris (Houston, Texas); Diane G. Edmondson (Houston, Texas) |
| ABSTRACT | Presented herein are compositions and methods for the long-term in vitro culturing of Treponema species such as T. pallidum. Culture media and systems for Treponema culture are also provided. |
| FILED | Friday, May 24, 2019 |
| APPL NO | 16/422155 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/18 (20130101) C12N 1/20 (20130101) Original (OR) Class C12N 5/06 (20130101) C12N 5/0018 (20130101) C12N 2502/09 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130951 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Jeannie T. Lee (Boston, Massachusetts); Athanasios Zovoilis (Cambridge, Massachusetts) |
| ABSTRACT | Methods of using B2 or Alu nucleic acids, or antisense oligonucleotides that modulate the EZH2/B2 or EZH2/Alu interaction and have the capacity to alter cleavage of B2 and Alu RNA, for increasing or decreasing cell and organismal viability. |
| FILED | Friday, June 09, 2017 |
| APPL NO | 16/308638 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/113 (20130101) C12N 2310/314 (20130101) C12N 2310/321 (20130101) C12N 2310/341 (20130101) C12N 2310/3145 (20130101) C12N 2310/3231 (20130101) C12N 2310/3233 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130989 | Chilkoti |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| INVENTOR(S) | Ashutosh Chilkoti (Durham, North Carolina) |
| ABSTRACT | An article such as a biosensor having a nonfouling surface thereon is described. The article comprises: (a) a substrate having a surface portion; (b) a linking layer on the surface portion; (c) a polymer layer comprising brush molecules formed on the linking layer; and (d) optionally but preferably, a first member of a specific binding pair (e.g., a protein, peptide, antibody, nucleic acid, etc.) coupled to the brush molecules. The polymer layer is preferably formed by the process of surface-initiated polymerization (SIP) of monomeric units thereon. Preferably, each of the monomeric units comprises a monomer (for example, a vinyl monomer) core group having at least one protein-resistant head group coupled thereto, to thereby form the brush molecule on the surface portion. Methods of using the articles are also described. |
| FILED | Tuesday, January 16, 2018 |
| APPL NO | 15/872392 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) B01J 2219/0061 (20130101) B01J 2219/0063 (20130101) B01J 2219/0074 (20130101) B01J 2219/00432 (20130101) B01J 2219/00596 (20130101) B01J 2219/00605 (20130101) B01J 2219/00608 (20130101) B01J 2219/00612 (20130101) B01J 2219/00626 (20130101) B01J 2219/00628 (20130101) B01J 2219/00635 (20130101) B01J 2219/00637 (20130101) B01J 2219/00659 (20130101) B01J 2219/00677 (20130101) B01J 2219/00722 (20130101) B01J 2219/00725 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 30/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/682 (20130101) Original (OR) Class C12Q 1/6837 (20130101) C12Q 1/6837 (20130101) C12Q 2521/131 (20130101) C12Q 2525/313 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 50/18 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5302 (20130101) G01N 33/54353 (20130101) G01N 33/54393 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130990 | Wu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Chao-ting Wu (Brookline, Massachusetts); George M. Church (Brookline, Massachusetts); Benjamin Richard Williams (Seattle, Washington) |
| ABSTRACT | Novel methods for making high resolution oligonucleotide paints are provided. Novel, high resolution oligonucleotide paints are also provided. |
| FILED | Friday, October 06, 2017 |
| APPL NO | 15/726870 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6841 (20130101) Original (OR) Class C12Q 1/6841 (20130101) C12Q 2537/143 (20130101) C12Q 2565/518 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130991 | He et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | THE UNIVERSITY OF CHICAGO (Chicago, Illinois) |
| INVENTOR(S) | Chuan He (Chicago, Illinois); Boxuan Simen Zhao (Chicago, Illinois); Pradnya Narkhede (Chicago, Illinois); Chang Liu (Chicago, Illinois); Xiaolong Cui (Chicago, Illinois) |
| ABSTRACT | Methods, compositions and kits are provided to amplify the amount of genomic methylated DNA can by subsequently analyzed and/or sequenced. It has particular use with small amounts of DNA, including, but not limited to cell free DNA samples. In some embodiments, the ratio of polymerase and methyltransferase is controlled in order to provide maximum yields. In some embodiments, a dual primase/polymerase is used. |
| FILED | Thursday, March 08, 2018 |
| APPL NO | 16/491278 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6844 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130992 | Makrigiorgos |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gerassimos Makrigiorgos (Chestnut Hill, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Gerassimos Makrigiorgos (Chestnut Hill, Massachusetts) |
| ABSTRACT | The present invention is directed to methods, compositions and reaction mixtures for multiplexing COLD-PCR/ice-COLD-PCR to enrich simultaneously several low abundance alleles (mutant target sequences) from a sample. The invention also involves COLD-PCR/ice-COLD-PCR amplification performed on DNA fragments that have different melting temperatures, and therefore different critical denaturation temperatures, in a graded temperature approach such that mutation enrichment is achieved on all diverse DNA fragments simultaneously (temperature-independent COLD-PCR or TI-COLD-PCR). The invention also involves methods for enabling identification of variant-sequence alleles in the presence of a large excess of non-variant alleles in nucleic acids without the complication of polymerase-introduced errors or other primer-introduced artifacts. |
| FILED | Friday, March 30, 2012 |
| APPL NO | 14/007173 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6853 (20130101) Original (OR) Class C12Q 1/6858 (20130101) C12Q 1/6858 (20130101) C12Q 2527/107 (20130101) C12Q 2537/143 (20130101) C12Q 2537/159 (20130101) C12Q 2537/163 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130996 | Salk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| INVENTOR(S) | Jesse Salk (Seattle, Washington); Lawrence A. Loeb (Bellevue, Washington); Michael Schmitt (Seattle, Washington) |
| ABSTRACT | Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand. This method uniquely capitalizes on the redundant information stored in double-stranded DNA, thus overcoming technical limitations of prior methods utilizing data from only one of the two strands. |
| FILED | Friday, August 31, 2018 |
| APPL NO | 16/119471 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6876 (20130101) Original (OR) Class C12Q 2525/179 (20130101) C12Q 2525/185 (20130101) C12Q 2525/191 (20130101) C12Q 2525/191 (20130101) C12Q 2535/119 (20130101) C12Q 2535/119 (20130101) C12Q 2535/122 (20130101) C12Q 2563/179 (20130101) C12Q 2565/514 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130998 | Jarrard et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | David Frazier Jarrard (Madison, Wisconsin); Bing Yang (Madison, Wisconsin) |
| ABSTRACT | A method of detecting the presence of a prostate cancer field defect in a human subject comprising the step of (a) obtaining genomic DNA from the human subject and (b) quantitating methylation in at least one target region selected from the group consisting of PLA2G16, CAV1, EVX1, MCF2L, FGF1, NCR2 and WNT2 and EXT1 and SPAG4 target, wherein significant methylation changes indicate the presence of prostate cancer or a prostate cancer field defect, wherein the change is relative to tissue from a second human subject who does not have prostate cancer. |
| FILED | Tuesday, November 14, 2017 |
| APPL NO | 15/811876 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6806 (20130101) C12Q 1/6853 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2337/00 (20130101) C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/154 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131615 | Savoy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nanohmics, Inc. (Austin, Texas) |
| ASSIGNEE(S) | Nanohmics, Inc. (Austin, Texas) |
| INVENTOR(S) | Steve M Savoy (Austin, Texas); Elzbieta A Ledwosinska (Austin, Texas); Jeremy J John (Austin, Texas); Kyle W Hoover (Austin, Texas); Daniel R Mitchell (Austin, Texas); Chris W Mann (Austin, Texas); Alexander P Greis (Austin, Texas) |
| ABSTRACT | An apparatus comprises a housing defining a chamber that has a liquid disposed therein, and a sensor submerged in the liquid. The sensor comprises a porous conductive film on a substrate, and the film comprises chemiresistive semiconducting metal oxide structures. The sensor also comprises an electrode pair operably connected to the porous conductive film for generating electric current in the film and for detecting a change in an electrical property of the film. The apparatus can be used to detect, identify, and quantify ions and molecules in a liquid sample. Molecules and ions, in a liquid sample, that interact with the porous conductive film can cause a change in an electrical property of the film. The change in electrical property of the film can be correlated with the presence and amount of the molecules or ions. |
| FILED | Thursday, June 06, 2019 |
| APPL NO | 16/434172 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/0606 (20130101) Original (OR) Class G01N 15/0656 (20130101) G01N 2015/0053 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131661 | Adzhubei et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (Washington, District of Columbia) |
| ASSIGNEE(S) | THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (Washington, District of Columbia) |
| INVENTOR(S) | Alexei Adzhubei (Moscow, Russian Federation); Michael Bukrinsky (Potomac, Maryland); Ruth Hunegnaw (Arlington, Virginia) |
| ABSTRACT | The invention relates to compounds and methods for restoring or preserving cholesterol efflux in a cell infected with Human Immunodeficiency Virus (HIV) by preventing or decreasing an interaction between Negative Regulatory Factor (Nef) protein and Calnexin protein, and methods for screening for such compounds. |
| FILED | Monday, April 06, 2020 |
| APPL NO | 16/841444 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/167 (20130101) A61K 31/404 (20130101) Acyclic or Carbocyclic Compounds C07C 223/06 (20130101) C07C 381/00 (20130101) Heterocyclic Compounds C07D 209/56 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) G01N 33/5041 (20130101) Original (OR) Class G01N 2333/163 (20130101) G01N 2333/4727 (20130101) G01N 2500/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131676 | Alaedini |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Armin Alaedini (New York, New York) |
| ABSTRACT | The present invention provides a method of using increased levels of one or more biomarkers to identify subjects having non-celiac gluten sensitivity or non-celiac wheat sensitivity. The identification would aid the physician or health professional to determine a specific treatment for the patient, for example, a diet that eliminates wheat, rye, and/or barley. In one embodiment, the biomarkers are one or more of soluble CD 14 (sCD14), lipopolysaccharide-binding protein (LBP), anti-lipopolysaccharide antibodies, anti-flagellin antibodies, anti-gliadin antibodies, and intestinal fatty acid-binding protein (FABP2). The present invention also provides a method of using the same markers to monitor the response to treatment for non-celiac wheat sensitivity in a subject. |
| FILED | Friday, February 24, 2017 |
| APPL NO | 16/079321 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/16 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) G01N 33/92 (20130101) G01N 33/564 (20130101) G01N 33/6893 (20130101) Original (OR) Class G01N 2333/4703 (20130101) G01N 2333/70596 (20130101) G01N 2800/02 (20130101) G01N 2800/24 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131677 | Prasad et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Bhagwat Prasad (Seattle, Washington); Abdul Basit (Seattle, Washington); Haeyoung Zhang (Seattle, Washington); John K. Amory (Seattle, Washington) |
| ABSTRACT | Treatment of testosterone deficiency in men by a precision medicine approach using a biomarker of activity of UGT2B17 that is involved in testosterone urinary elimination. By inhibiting UGT2B17, alone or in combination with administration of testosterone, testosterone deficiency in men can be treatable. Further, a method of dose selection for precise dosing of UGT2B17 substrate drugs is provided. Additionally, methods for safe dosing of pharmaceutical agents that undergo UGT2B17-mediated acyl glucuronidation are provided. |
| FILED | Wednesday, April 10, 2019 |
| APPL NO | 16/380876 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/167 (20130101) A61K 31/192 (20130101) A61K 31/196 (20130101) A61K 31/506 (20130101) A61K 31/4365 (20130101) A61K 31/5685 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 5/26 (20180101) Enzymes C12Y 204/01017 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) G01N 33/743 (20130101) Original (OR) Class G01N 2333/91102 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131732 | Park et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Silver Spring, Maryland) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Silver Spring, Maryland) |
| INVENTOR(S) | Bu S. Park (Bethesda, Maryland); Brenton McCright (Gaithersburg, Maryland); Sunder S. Rajan (Warrenton, Virginia) |
| ABSTRACT | An apparatus, method, and system are disclosed for improving uniformity of RF magnetic field in an MRI system, and thereby improving both signal-to-noise ratio and uniformity of imaging sensitivity across a sampling volume, to provide more uniform MRI images. A passive LC resonator develops induced EMF and induced currents in a primary RF magnetic field; the secondary magnetic field produced thereby can counteract magnetic field amplitude gradients to produce a more homogeneous RF magnetic field. In systems with separate transmit and receive coils, a shunt detuning circuit is pulsed ON to prevent interference during the transmit period. In a dual-frequency MRI machine (e.g. 19F and 1H), the RF magnetic field at the lower operating frequency can be homogenized by tuning the resonance of the passive resonator between the two operating frequencies. Another resonator can improve RF field uniformity at the higher operating frequency. Variants and experimental results are disclosed. |
| FILED | Friday, October 26, 2018 |
| APPL NO | 16/760202 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/3635 (20130101) G01R 33/3642 (20130101) Original (OR) Class G01R 33/5659 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131733 | Jiang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio); Siemens Healthcare GmbH (Erlangen, Germany) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio); Siemens Healthcare GmbH (Erlangen, Germany) |
| INVENTOR(S) | Yun Jiang (Cleveland, Ohio); Mark A. Griswold (Shaker Heights, Ohio); Gregor Korzdorfer (Erlangen, Germany); Mathias Nittka (Erlangen, Germany) |
| ABSTRACT | A system and method is provided for acquisition of magnetic resonance fingerprinting (“MRF”) data that includes determining a non-locally sequential sampling pattern for a Cartesian grid of k-space, performing a series of sequence blocks using acquisition parameters that vary between sequence blocks to acquire MRF data from a subject using the Cartesian grid of k-space and the determined non-locally sequential sampling pattern, assembling the MRF data into a series of signal evolutions, comparing the series of signal evolutions to a dictionary of known signal evolutions to determine tissue properties of the subject, and generating a report indicating the tissue properties of the subject. |
| FILED | Monday, April 27, 2020 |
| APPL NO | 16/859175 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) Original (OR) Class G01R 33/482 (20130101) G01R 33/543 (20130101) G01R 33/5608 (20130101) G01R 33/5615 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131737 | Frank et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Lawrence R. Frank (San Diego, California); Vitaly L. Galinsky (San Diego, California) |
| ABSTRACT | A method and for estimating local diffusion anisotropy and global tractography within neural architecture from diffusion weighted magnetic resonance image (dMRI) data uses a computer processor to integrate a first dataset comprising standard single pulsed field gradient (sPFG) dMRI data with a second dataset comprising double pulsed field gradient (dPFG) dMRI data into a common coordinate system with the same spatial resolution. The resulting image includes integrated macroscopic and microscopic anisotropy and global tractography within the target volume. |
| FILED | Thursday, June 04, 2020 |
| APPL NO | 16/893344 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5608 (20130101) G01R 33/56341 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131738 | Johnson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Curtis L. Johnson (Wilmington, Delaware); Bradley P. Sutton (Savoy, Illinois); Joseph L. Holtrop (Memphis, Tennessee) |
| ABSTRACT | A method and system provides an acquisition scheme for generating magnetic resonance elastography displacement data with whole-sample coverage, high spatial resolution, and adequate SNR in a short scan time. The method and system can acquire in-plane and through-plane k-space shots over a volume of a sample divided into a plurality of slabs that each include a plurality of non-adjacent slices to obtain three dimensional multiband, multishot data, can apply multiband radio frequency refocusing pulses to the sample, can acquire navigators before readout, and can correct for non-linear motion errors. |
| FILED | Friday, September 27, 2019 |
| APPL NO | 16/585539 |
| ART UNIT | 2868 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4826 (20130101) G01R 33/4835 (20130101) G01R 33/5611 (20130101) G01R 33/5673 (20130101) Original (OR) Class G01R 33/5676 (20130101) G01R 33/56358 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11132178 | Plusquellic |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | STC.UNM (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James Plusquellic (Albuquerque, New Mexico) |
| ABSTRACT | This disclosure describes techniques for analyzing statistical quality of bitstrings produced by a physical unclonable function (PUF). The PUF leverages resistance variations in the power grid wires of an integrated circuit. Temperature and voltage stability of the bitstrings are analyzed. The disclosure also describes converting a voltage drop into a digital code, wherein the conversion is resilient to simple and differential side-channel attacks. |
| FILED | Thursday, April 23, 2020 |
| APPL NO | 16/856887 |
| ART UNIT | 2182 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 7/588 (20130101) Original (OR) Class G06F 2207/58 (20130101) Ciphering or Deciphering Apparatus for Cryptographic or Other Purposes Involving the Need for Secrecy G09C 1/00 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/002 (20130101) H04L 9/0866 (20130101) H04L 2209/12 (20130101) H04L 2209/26 (20130101) Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 40/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE48751 | Govindan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Immunomedics, Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Immunomedics, Inc. (Morris Plains, New Jersey) |
| INVENTOR(S) | Serengulam V. Govindan (Summit, New Jersey); Sung-Ju Moon (New Providence, New Jersey); David M. Goldenberg (Mendham, New Jersey) |
| ABSTRACT | The present invention relates to therapeutic conjugates with improved ability to target various diseased cells containing a targeting moiety (such as an antibody or antibody fragment), a linker and a therapeutic moiety, and further relates to processes for making and using the conjugates. |
| FILED | Wednesday, December 12, 2018 |
| APPL NO | 16/218384 |
| ART UNIT | 3991 — Central Reexamination Unit (Chemical) |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4745 (20130101) A61K 45/06 (20130101) A61K 47/6803 (20170801) Original (OR) Class A61K 47/6841 (20170801) A61K 47/6849 (20170801) A61K 47/6851 (20170801) A61K 47/6853 (20170801) A61K 47/6855 (20170801) A61K 47/6857 (20170801) A61K 47/6861 (20170801) A61K 47/6889 (20170801) A61K 2039/505 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) Heterocyclic Compounds C07D 491/22 (20130101) Peptides C07K 16/18 (20130101) C07K 16/30 (20130101) C07K 16/303 (20130101) C07K 16/1063 (20130101) C07K 16/2803 (20130101) C07K 16/2833 (20130101) C07K 16/2863 (20130101) C07K 16/2887 (20130101) C07K 16/3046 (20130101) C07K 16/3076 (20130101) C07K 16/3092 (20130101) C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/31 (20130101) C07K 2317/40 (20130101) C07K 2317/52 (20130101) C07K 2317/53 (20130101) C07K 2317/94 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11129811 | Ketter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Patrick Ketter (San Antonio, Texas); Bernard Arulanandam (Helotes, Texas); M. Neal Guentzel (San Antonio, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Patrick Ketter (San Antonio, Texas); Bernard Arulanandam (Helotes, Texas); M. Neal Guentzel (San Antonio, Texas) |
| ABSTRACT | Certain embodiments are directed to methods and compositions for preventing or treating bacterial infections. In certain embodiments the compositions comprise thioredoxin inhibitors, and/or thioredoxin-like inhibitors. |
| FILED | Thursday, July 11, 2019 |
| APPL NO | 16/508883 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/52 (20130101) A61K 31/52 (20130101) A61K 31/428 (20130101) A61K 31/428 (20130101) A61K 31/437 (20130101) A61K 31/437 (20130101) A61K 31/522 (20130101) A61K 31/522 (20130101) A61K 31/4164 (20130101) Original (OR) Class A61K 31/4164 (20130101) A61K 31/4184 (20130101) A61K 31/4184 (20130101) A61K 31/4196 (20130101) A61K 31/4196 (20130101) A61K 31/5415 (20130101) A61K 31/5415 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11129921 | Kaplan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
| ASSIGNEE(S) | Trustees of Tufts College (Medford, Massachusetts) |
| INVENTOR(S) | David L. Kaplan (Concord, Massachusetts); Ung-Jin Kim (Daejeon, South Korea); Jaehyung Park (Decatur, Georgia); Hyoung-Joon Jin (Seoul, South Korea) |
| ABSTRACT | The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels. |
| FILED | Wednesday, May 08, 2019 |
| APPL NO | 16/406538 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/38 (20130101) A61L 27/52 (20130101) A61L 27/56 (20130101) A61L 27/227 (20130101) Original (OR) Class A61L 27/3604 (20130101) A61L 2430/02 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 39/003 (20130101) B29C 39/203 (20130101) B29C 55/005 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 7/01 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2089/00 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2007/00 (20130101) B29L 2009/00 (20130101) Peptides C07K 14/43536 (20130101) C07K 14/43586 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/07 (20130101) C08J 3/075 (20130101) C08J 5/18 (20130101) C08J 9/26 (20130101) C08J 9/28 (20130101) C08J 9/0061 (20130101) C08J 2201/0444 (20130101) C08J 2201/0504 (20130101) C08J 2205/022 (20130101) C08J 2389/00 (20130101) Compositions of Macromolecular Compounds C08L 89/00 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0007 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 4/02 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/249921 (20150401) Y10T 442/10 (20150401) Y10T 442/60 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130329 | McIver et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Carl R. McIver (Everett, Washington); Brice A. Johnson (Federal Way, Washington); Michael R. Anderson (Renton, Washington) |
| ABSTRACT | An apparatus is provided for peeling a liner away from a substrate. The apparatus comprises a first member rotatable about an axis. The apparatus also comprises a second member disposed on the first member and for generating a suction force to be applied to the liner to peel a portion of the liner away from the substrate when the suction force of the second member is applied to the liner and the first member is rotating about its axis. The apparatus further comprises a third member synchronized to rotation of the first member about its axis such that the third member clamps the peeled portion of the liner against the first member while the second member is applying suction force to the liner and the first member is rotating about its axis. |
| FILED | Friday, February 07, 2020 |
| APPL NO | 16/784732 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 38/10 (20130101) B32B 43/006 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 156/1132 (20150115) Y10T 156/1174 (20150115) Y10T 156/1195 (20150115) Y10T 156/1944 (20150115) Y10T 156/1978 (20150115) Y10T 156/1994 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130569 | Easley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Textron Innovations Inc. (Providence, Rhode Island) |
| ASSIGNEE(S) | Textron Innovations Inc. (Providence, Rhode Island) |
| INVENTOR(S) | Dakota Charles Easley (Hurst, Texas); Levi Charles Hefner (Arlington, Texas) |
| ABSTRACT | An unmanned aircraft system having a flying wing orientation includes an airframe having leading and trailing edges, a two-dimensional thrust array coupled to the leading edge, a power system and a flight control system operable to independently control the speed of each propulsion assembly of the two-dimensional thrust array. In the flying wing orientation, the two-dimensional distributed thrust array provides airspeed control responsive to collectively changing the speed of each propulsion assembly, pitch authority responsive to differentially changing the speed of the propulsion assemblies above the airframe relative to the propulsion assemblies below the airframe, roll authority responsive to differentially changing the speed of the propulsion assemblies rotating clockwise relative to the propulsion assemblies rotating counterclockwise and yaw authority responsive to differentially changing the speed of the propulsion assemblies on a port side of the airframe relative to the propulsion assemblies on a starboard side of the airframe. |
| FILED | Tuesday, July 10, 2018 |
| APPL NO | 16/031771 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) Original (OR) Class B64C 2201/20 (20130101) B64C 2201/024 (20130101) B64C 2201/028 (20130101) B64C 2201/042 (20130101) B64C 2201/108 (20130101) B64C 2201/141 (20130101) B64C 2201/146 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/26 (20130101) B64D 31/06 (20130101) B64D 2027/262 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0808 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130675 | Baker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Colin C. Baker (Alexandria, Virginia); Woohong Kim (Lorton, Virginia); Guillermo R. Villalobos (Springfield, Virginia); Jasbinder S. Sanghera (Ashburn, Virginia); Ishwar D. Aggarwal (Charlotte, North Carolina) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Colin C. Baker (Alexandria, Virginia); Woohong Kim (Lorton, Virginia); Guillermo R. Villalobos (Springfield, Virginia); Jasbinder S. Sanghera (Ashburn, Virginia); Ishwar D. Aggarwal (Charlotte, North Carolina) |
| ABSTRACT | A nanoparticle containing monoclinic lutetium oxide. A method of: dispersing a lutetium salt solution in a stream of oxygen gas to form droplets, and combusting the droplets to form nanoparticles containing lutetium oxide. The combustion occurs at a temperature sufficient to form monoclinic lutetium oxide in the nanoparticles. An article containing lutetium oxide and having an average grain size of at most 10 microns. |
| FILED | Wednesday, August 15, 2012 |
| APPL NO | 13/585884 |
| ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Original (OR) Class B82Y 40/00 (20130101) Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 17/224 (20200101) C01F 17/241 (20200101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 1/02 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/54 (20130101) C01P 2002/72 (20130101) C01P 2004/03 (20130101) C01P 2004/52 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/50 (20130101) C04B 35/6455 (20130101) C04B 35/62665 (20130101) C04B 2235/72 (20130101) C04B 2235/443 (20130101) C04B 2235/445 (20130101) C04B 2235/762 (20130101) C04B 2235/786 (20130101) C04B 2235/3203 (20130101) C04B 2235/5445 (20130101) C04B 2235/5454 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/7767 (20130101) C09K 11/7769 (20130101) C09K 11/7784 (20130101) Hot Gas or Combustion-product Positive-displacement Engine Plants; Use of Waste Heat of Combustion Engines; Not Otherwise Provided for F02G 2258/10 (20130101) F02G 2258/90 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130774 | Meylemans |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Heather A. Meylemans (Camarillo, California) |
| ABSTRACT | A series of 2,2′-dipyridyl ketone (DPK) containing metal complexes have been synthesized with metals including Mn, Fe, Co, Ni, Cu, Ru, Pd, and Pt. These complexes have one, two or three DPK ligands chelated to the metal center. In addition to the DPK ligands the complexes can comprise halogen ligands that can easily exchange with carbon dioxide to allow for reduction to small molecules such as methanol or oxalate. Initial electrochemical measurements show a reversible binding of carbon dioxide to the metal catalyst. |
| FILED | Monday, May 13, 2019 |
| APPL NO | 16/409950 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/127 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 1/08 (20130101) C07F 15/065 (20130101) Original (OR) Class Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/02 (20130101) C10L 1/04 (20130101) C10L 2290/38 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/25 (20210101) C25B 11/075 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130801 | Medof et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | M. Edward Medof (Pepper Pike, Ohio); Michael G. Strainic (Westlake, Ohio); Elliot Pohlmann (Roanoke, Virginia); Ming-Shih Hwang (Danbury, Connecticut) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | M. Edward Medof (Pepper Pike, Ohio); Michael G. Strainic (Westlake, Ohio); Elliot Pohlmann (Roanoke, Virginia); Ming-Shih Hwang (Danbury, Connecticut) |
| ABSTRACT | A method of modulating growth factor responses of cells expressing C3a receptor (C3aR) and C5a receptor (C5aR) and at least one growth factor receptor includes administering to the cells at least one agent that modulates C3aR and/or C5aR signaling of the cells. |
| FILED | Friday, January 13, 2012 |
| APPL NO | 13/350402 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/06 (20130101) A61K 38/08 (20130101) A61K 38/57 (20130101) A61K 38/58 (20130101) A61K 45/06 (20130101) A61K 2039/507 (20130101) Peptides C07K 16/18 (20130101) Original (OR) Class C07K 16/28 (20130101) C07K 16/248 (20130101) C07K 2317/32 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) G01N 2500/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130895 | Trifu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ASPEN AEROGELS,INC. (Northborough, Massachusetts) |
| ASSIGNEE(S) | Aspen Aerogels, Inc. (Northborough, Massachusetts) |
| INVENTOR(S) | Roxana Trifu (Worcester, Massachusetts); Redouane Begag (Hudson, Massachusetts); George Gould (Mendon, Massachusetts); Shannon White (Bolton, Massachusetts) |
| ABSTRACT | The present disclosure can provide aerogel compositions which have a thermal storage capacity, and which are durable and easy to handle. The present disclosure can provide aerogel compositions which include PCM coatings, particle mixtures, or PCM materials confined within the porous network of an aerogel composition. The present disclosure can provide methods for producing aerogel compositions by coating an aerogel composition with PCM materials, by forming particle mixtures with PCM materials, or by confining PCM materials within the porous network of an aerogel composition. |
| FILED | Tuesday, September 20, 2016 |
| APPL NO | 15/270759 |
| ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/18 (20130101) B32B 2266/102 (20161101) B32B 2266/126 (20161101) Non-metallic Elements; Compounds Thereof; C01B 33/1585 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/0009 (20130101) C08J 9/0014 (20130101) C08J 9/0023 (20130101) C08J 9/42 (20130101) C08J 9/0061 (20130101) C08J 9/0066 (20130101) C08J 9/0085 (20130101) C08J 9/286 (20130101) C08J 9/365 (20130101) C08J 2201/05 (20130101) C08J 2205/026 (20130101) C08J 2375/02 (20130101) C08J 2423/06 (20130101) C08J 2471/02 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/16 (20130101) C08K 5/01 (20130101) C08K 5/053 (20130101) C08K 2003/162 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 5/063 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/249953 (20150401) Y10T 428/249955 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130910 | Rand et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Barry Rand (Princeton, New Jersey); Ross Kerner (Princeton, New Jersey); Zhengguo Xiao (Plainsboro, New Jersey) |
| ABSTRACT | Organic-inorganic perovskite nanoparticle compositions are described herein. In some embodiments, a nanoparticle composition comprises a layer of organic-inorganic perovskite nanocrystals, the organic-inorganic perovskite nanocrystals comprising surfaces associated with ligands of size unable to incorporate into octahedral corner sites of the perovskite crystal structure. |
| FILED | Wednesday, March 22, 2017 |
| APPL NO | 16/095579 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) Original (OR) Class C09K 11/025 (20130101) C09K 2211/10 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/14 (20130101) C30B 29/12 (20130101) C30B 29/60 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/2009 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/42 (20130101) H01L 51/0077 (20130101) H01L 51/4253 (20130101) H01L 51/5032 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130955 | Chaikind et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Zymergen Inc. (Emeryville, California) |
| ASSIGNEE(S) | Zymergen Inc. (Emeryville, California) |
| INVENTOR(S) | Brian Chaikind (Orinda, California); Hendrik M. Van Rossum (Delft, Netherlands); Aaron Miller (El Cerrito, California); Paul Perkovich (Berkeley, California); Shawn Szyjka (Martinez, California); Kedar Patel (Fremont, California) |
| ABSTRACT | Methods, compositions, and kits for high throughput DNA assembly reactions in vitro. Modular CRISPR DNA constructs comprising modular insert DNA parts flanked by cloning tag segments comprising pre-validated CRISPR protospacer/protospacer adjacent motif sequence combinations. High throughput methods of CRISPRi and CRISPRa. |
| FILED | Thursday, August 15, 2019 |
| APPL NO | 16/541354 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/64 (20130101) Original (OR) Class C12N 15/102 (20130101) C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131039 | Hobart et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Karl D. Hobart (Alexandria, Virginia); Tatyana I. Feygelson (Springfield, Virginia); Marko J. Tadjer (Springfield, Virginia); Travis J. Anderson (Alexandria, Virginia); Andrew D. Koehler (Alexandria, Virginia); Samuel Graham, Jr. (Lithonia, Georgia); Mark Goorsky (Valencia, California); Zhe Cheng (Atlanta, Georgia); Luke Yates (Atlanta, Georgia); Tingyu Bai (Los Angeles, California); Yekan Wang (Los Angeles, California) |
| ABSTRACT | A method for growing polycrystalline diamond films having engineered grain growth and microstructure. Grain growth of a polycrystalline diamond film on a substrate is manipulated by growing the diamond on a nanopatterned substrate having features on the order of the initial grain size of the diamond film. By growing the diamond on such nanopatterned substrates, the crystal texture of a polycrystalline diamond film can be engineered to favor the preferred <110> orientation texture, which in turn enhances the thermal conductivity of the diamond film. |
| FILED | Thursday, May 23, 2019 |
| APPL NO | 16/420366 |
| ART UNIT | 1783 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/18 (20130101) C30B 29/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131192 | Goldfarb et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Michael Goldfarb (Nashville, Tennessee); Harrison Bartlett (Nashville, Tennessee); Beau Johnson (Nashville, Tennessee) |
| ABSTRACT | A cylinder actuator includes a body assembly and a piston assembly. The body assembly includes a first cylinder nested concentrically within a second cylinder. The piston assembly slides linearly within the first and second cylinders. The piston assembly includes a first piston assembly end and a second piston assembly end. The first piston assembly end includes first and second pistons. The first piston moves within the first cylinder. The second piston moves within the second cylinder. The piston assembly includes first and second piston rods. The first piston rod extends from the first piston through a first end of the first cylinder. The second piston rod extends from the second piston through a first end of the second cylinder. The piston rods are joined at the second end of the piston rod assembly located outside of the first and second cylinders. |
| FILED | Friday, February 01, 2019 |
| APPL NO | 16/963939 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Machines or Engines, in General or of Positive-displacement Type, e.g Steam Engines F01B 7/16 (20130101) Original (OR) Class Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 2211/7055 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131212 | Spangler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Brandon W. Spangler (Vernon, Connecticut); Adam P. Generale (Dobbs Ferry, New York); Ky H. Vu (East Hartford, Connecticut) |
| ABSTRACT | A component for a gas turbine engine includes a platform that has a gas path side and a non-gas path side. At least one airfoil extends from the gas path side of the platform. At least one airfoil includes a serpentine cavity and a serpentine turn extends from the non-gas path side of the platform. A cover plate is located adjacent the non-gas path side of the platform. The cover plate includes a first plurality of fluid openings that extend through the cover plate. At least one bulge at least partially defines a fluid passageway with the serpentine turn. |
| FILED | Wednesday, December 06, 2017 |
| APPL NO | 15/832925 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/147 (20130101) F01D 5/188 (20130101) F01D 9/041 (20130101) F01D 25/12 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2240/81 (20130101) F05D 2240/122 (20130101) F05D 2250/185 (20130101) F05D 2260/201 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131425 | Vizzio et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (, None) |
| INVENTOR(S) | Paul J Vizzio (New York, New York); David J Bamford (Wakefield, Rhode Island); Adam B Proulx (Whitman, Massachusetts) |
| ABSTRACT | A stabilization system is provided with at least one sensor to measure and correct orientation of a platform relative to an inertial reference frame. A roll motor is affixed to a platform for pivoting the platform about a roll axis and an elevation motor is configured to rotate the platform about an elevation axis. A rotation motor pivots the platform about an azimuth axis. A control system using the sensor measurements, actuates the roll motor, elevation motor and the rotation motor to maintain a substantially constant orientation of the platform relative to the inertial frame of reference. The rotation motor, the elevation motor and the roll motor are spaced apart from each other along the azimuth axis. |
| FILED | Tuesday, September 15, 2020 |
| APPL NO | 17/020904 |
| ART UNIT | 3631 — Static Structures, Supports and Furniture |
| CURRENT CPC | Frames, Casings or Beds of Engines, Machines or Apparatus, Not Specific to Engines, Machines or Apparatus Provided for Elsewhere; Stands; Supports F16M 11/18 (20130101) Original (OR) Class F16M 11/046 (20130101) F16M 11/126 (20130101) Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 11/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131527 | Kruft et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jonathan G. Kruft (Rockville, Maryland); Brandon L. Good (Doylestown, Pennsylvania); David A. Roper, Jr. (Glen Burnie, Maryland) |
| ABSTRACT | According to exemplary inventive practice, ceramic powder or slurry is selectively deposited at many discrete locations on each of many fiberglass fabric substrates. The sizes and/or shapes of the ceramic deposits vary among the substrates. The substrates are selectively ordered and stacked so that perpendicular through-plane alignments of respective ceramic deposits form selected three-dimensional geometric shapes. The resultant stack of substrates, characterized by many three-dimensional ceramic inclusions, is impregnated with an elastomer or an epoxy that binds the ceramic-deposited substrates together, resulting in a finished composite product. Inventive composite structures can be multifariously designed and embodied to afford selected ballistic and/or structural and/or electromagnetic qualities. Another mode of inventive practice provides for incorporation of the above-described inventive composite product as a layer in a multilayer composite system that also includes a high strain-rate-sensitivity-hardening polymer layer, a hybrid composite fabric layer, a ceramic layer, and a polymeric ballistic fabric layer. |
| FILED | Wednesday, November 23, 2016 |
| APPL NO | 15/360734 |
| ART UNIT | 1789 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/266 (20130101) B32B 5/022 (20130101) B32B 5/024 (20130101) B32B 5/26 (20130101) B32B 9/047 (20130101) B32B 27/12 (20130101) B32B 27/40 (20130101) B32B 2250/05 (20130101) B32B 2260/04 (20130101) B32B 2260/021 (20130101) B32B 2262/14 (20130101) B32B 2262/101 (20130101) B32B 2262/0253 (20130101) B32B 2264/107 (20130101) B32B 2307/54 (20130101) B32B 2307/558 (20130101) B32B 2571/02 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 5/0428 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131533 | Albrecht |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Nicholas H. Albrecht (Ridgecrest, California) |
| ABSTRACT | Shock resistant mounting structures for fuze systems. The shock resistant mounting structures may comprise: a shock resistant base cap and a shock resistant washer. The shock resistant base cap may comprise a circular cap housing and a plurality of first cripple studs disposed within the circular cap housing. The circular cap housing may be configured to engage a flange end of a fuze and may be adapted to snugly fit within a fuze well. The shock resistant washer may comprise a ring-shaped housing and one or more second cripple studs radially disposed within the ring-shaped housing. The ring-shaped housing may have a center opening adapted to engage a fuze body. When installed, the shock resistant base cap and shock resistant washer may be disposed within the fuze well and may minimize or divert shock loading energy from entering a fuze. |
| FILED | Wednesday, January 08, 2020 |
| APPL NO | 16/737214 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 39/24 (20130101) Ammunition Fuzes; Arming or Safety Means Therefor F42C 19/02 (20130101) F42C 19/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131615 | Savoy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nanohmics, Inc. (Austin, Texas) |
| ASSIGNEE(S) | Nanohmics, Inc. (Austin, Texas) |
| INVENTOR(S) | Steve M Savoy (Austin, Texas); Elzbieta A Ledwosinska (Austin, Texas); Jeremy J John (Austin, Texas); Kyle W Hoover (Austin, Texas); Daniel R Mitchell (Austin, Texas); Chris W Mann (Austin, Texas); Alexander P Greis (Austin, Texas) |
| ABSTRACT | An apparatus comprises a housing defining a chamber that has a liquid disposed therein, and a sensor submerged in the liquid. The sensor comprises a porous conductive film on a substrate, and the film comprises chemiresistive semiconducting metal oxide structures. The sensor also comprises an electrode pair operably connected to the porous conductive film for generating electric current in the film and for detecting a change in an electrical property of the film. The apparatus can be used to detect, identify, and quantify ions and molecules in a liquid sample. Molecules and ions, in a liquid sample, that interact with the porous conductive film can cause a change in an electrical property of the film. The change in electrical property of the film can be correlated with the presence and amount of the molecules or ions. |
| FILED | Thursday, June 06, 2019 |
| APPL NO | 16/434172 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/0606 (20130101) Original (OR) Class G01N 15/0656 (20130101) G01N 2015/0053 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131619 | Ozdemir et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Sahin Kaya Ozdemir (St. Louis, Missouri); Lan Yang (St. Louis, Missouri); Bo Peng (St. Louis, Missouri) |
| ABSTRACT | A system and method for engineering loss in a physical system by steering parameters of the physical system to the vicinity of an exceptional point is disclosed. In the vicinity of an exceptional point, localization of the fields helps to enhance any linear or nonlinear processes. As examples loss-induced transparency in the intracavity field intensities of coupled resonators, loss-induced suppression and enhancement of thermal nonlinearity in coupled resonators and loss-induced suppression and revival of Raman lasing in whispering-gallery-microcavities are demonstrated. |
| FILED | Wednesday, May 16, 2018 |
| APPL NO | 15/981228 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1434 (20130101) Original (OR) Class G01N 21/7746 (20130101) G01N 2021/655 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/88 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131627 | Bachalo |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Artium Technologies, Inc. (Sunnyvale, California) |
| ASSIGNEE(S) | Artium Technologies, Inc. (Sunnyvale, California) |
| INVENTOR(S) | William D. Bachalo (Los Altos Hills, California) |
| ABSTRACT | An apparatus to detect contaminants in a fuel comprises an input to receive a fuel flow. A light scattering system is coupled to the input. An imaging system is coupled to the light scattering system. A memory is coupled to the imaging system. A processor is coupled to the memory. Output signals from the imaging and light scattering systems are transferred to the processor. The processor is configured to cause the light scattering system to monitor the light scattering intensity from the contaminants in the fuel flow. The processor is configured to cause the light scattering system to measure a light scattering intensity signal from the contaminants in the fuel flow. The processor is configured to generate a trigger signal to turn on the imaging system when the light scattering intensity is greater than a predetermined threshold. |
| FILED | Wednesday, February 07, 2018 |
| APPL NO | 15/890559 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Controlling Combustion Engines F02D 41/22 (20130101) F02D 2200/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/06 (20130101) G01N 15/0227 (20130101) G01N 21/53 (20130101) G01N 21/85 (20130101) G01N 21/3577 (20130101) Original (OR) Class G01N 33/2835 (20130101) G01N 2015/003 (20130101) G01N 2015/0053 (20130101) G01N 2015/0693 (20130101) G01N 2021/4711 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131635 | Gupta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LASER and PLASMA TECHNOLOGIES, LLC (Hampton, Virginia) |
| ASSIGNEE(S) | LASER and PLASMA TECHNOLOGIES, LLC (Hampton, Virginia) |
| INVENTOR(S) | Mool C. Gupta (Yorktown, Virginia); Alexander C. Edrington (Norfolk, Virginia); James I. Harp (Williamsburg, Virginia); Waverley D. Marsh (Hampton, Virginia); Guoqing Paul Shen (Blacksburg, Virginia) |
| ABSTRACT | An infrared detection camera for the inspection of coated substrates. A corrosion sensing instrument is handheld, portable, battery powered, compact and lightweight. The camera performs nondestructive, real time imaging of corrosion and defects beneath painted metal or plastics or composite surfaces. The device includes a user-friendly computer interface for real time imaging and image storage capability and is typically used for detecting early stage corrosion beneath painted aircraft aluminum surfaces. The handheld device has a front “open air” imaging port which is designed to be placed in soft contact against the painted surface to be inspected by the instrument. The device includes an infrared camera and infrared lighting to capture an image of the surface. The captured image is transferred to a computer and analyzed to locate imperfections below a coating on a surface. |
| FILED | Friday, May 29, 2020 |
| APPL NO | 16/888140 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/8422 (20130101) Original (OR) Class G01N 21/8806 (20130101) G01N 2021/8427 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131701 | Mathis |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as Represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Ronald F. Mathis (Camarillo, California) |
| ABSTRACT | A multi-probe anechoic chamber (MPAC) for beam performance testing of a phased array system, including an active electronically steered array (AESA) system. The MPAC may comprise: an AESA antenna having a plurality of subarrays capable of emitting RF energy; an anechoic chamber having a wall, comprising a plurality of horn antennas for receiving the RF energy; a switch electrically coupled to the horn antennas for selectively coupling of the horn antennas to one or more output channels; various instruments electrically coupled to the output channels for measuring the RF energy; and a processor electrically coupled to the switch and the instruments for controlling the selective coupling of the switch, such that the processor and instruments cooperatively monitor and measure various beam parameters associated with the RF energy. The various beam parameters may include: signal-to-noise ratio, signal strength, beam phase, phase stability, frequency stability, beam shape, beam pointing accuracy, and beam switching rates. |
| FILED | Wednesday, July 03, 2019 |
| APPL NO | 16/503174 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 29/0821 (20130101) Original (OR) Class Antennas, i.e Radio Aerials H01Q 21/064 (20130101) Transmission H04B 17/15 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131741 | Ranney et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Army Research Laboratory ATTN: RDRL-LOC-I (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Kenneth Irving Ranney (Rockville, Maryland); Gregory James Mazzaro (Charleston, South Carolina); Kyle Alexander Gallagher (Silver Spring, Maryland); Stephen Freeman (Ellicott City, Maryland) |
| ABSTRACT | A method and apparatus for receiving signals from an unknown transmitting source and providing the location of the unknown transmitting source comprising a series of channels for receiving signals radiated by the unknown transmitting sources, generating preprocessed time domain data and generating a SAR image depicting a location of the unknown transmitting source, and a processor for processing the preprocessed time domain data to enhance a pixel value at each pixel location within the SAR image by summing signal data from each channel related to each pixel location to generate an enhanced SAR image. |
| FILED | Thursday, August 30, 2018 |
| APPL NO | 16/117346 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/043 (20130101) G01S 3/046 (20130101) Original (OR) Class G01S 13/90 (20130101) G01S 13/9004 (20190501) G01S 13/9005 (20130101) G01S 13/9019 (20190501) G01S 13/9021 (20190501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131860 | Mitchell |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wavefront Research, Inc. (Northampton, Pennsylvania) |
| ASSIGNEE(S) | Wavefront Research, Inc. (Northhampton, Pennsylvania) |
| INVENTOR(S) | Thomas A. Mitchell (Nazareth, Pennsylvania) |
| ABSTRACT | Imagers and imaging spectrometers, which are more compact in physical size with wider spatial fields than previous designs and include axis bending elements, are disclosed. |
| FILED | Thursday, September 08, 2016 |
| APPL NO | 15/259740 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/14 (20130101) G01J 3/2823 (20130101) G01J 2003/1208 (20130101) Optical Elements, Systems, or Apparatus G02B 27/126 (20130101) G02B 27/1013 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131898 | Basu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Rajratan Basu (Annapolis, Maryland); Daniel Kinnamon (Annapolis, Maryland); Christopher M. Spillmann (Annandale, Virginia); Jakub Kolacz (Washington, District of Columbia); Jesse A. Frantz (Washington, District of Columbia); Jason D. Myers (Alexandria, Virginia) |
| ABSTRACT | A graphene and liquid crystal device comprising a substrate, a layer of graphene on the substrate, and a layer of liquid crystal on the layer of graphene. A graphene and liquid crystal device wherein the layer of graphene is an alignment layer and an electrode for a liquid crystal device. |
| FILED | Thursday, January 09, 2020 |
| APPL NO | 16/738150 |
| ART UNIT | 2871 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/155 (20130101) G02F 1/0316 (20130101) G02F 1/1337 (20130101) G02F 1/1357 (20210101) G02F 1/1418 (20130101) Original (OR) Class G02F 1/133711 (20130101) G02F 1/133738 (20210101) G02F 1/133753 (20130101) G02F 1/133757 (20210101) G02F 1/133796 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11132017 | Strong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
| ASSIGNEE(S) | NORTHROP GRUMANN SYSTEMS CORPORATION (Falls Church, Virginia) |
| INVENTOR(S) | Joshua A. Strong (Ellicott City, Maryland); Max E. Nielsen (Caldwell, Idaho) |
| ABSTRACT | One embodiment includes a clock distribution system. The system includes at least one resonator spine that propagates a clock signal and at least one resonator rib conductively coupled to the at least one resonator spine and being arranged as a standing wave resonator. At least one of the at least one resonator rib has a thickness that varies along a length of the respective one of the at least one resonator rib. The system also includes at least one transformer-coupling line. Each of the at least one transformer-coupling line can be conductively coupled to an associated circuit and being inductively coupled to the at least one resonator rib to inductively generate a clock current corresponding to the clock signal to provide functions for the associated circuit. |
| FILED | Tuesday, November 24, 2020 |
| APPL NO | 17/103055 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 1/10 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/66 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 7/082 (20130101) Pulse Technique H03K 5/15013 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11132057 | Keesling |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Applied Invention, LLC (Burbank, California) |
| ASSIGNEE(S) | APPLIED INVENTION, LLC (Burbank, California) |
| INVENTOR(S) | Michael Keesling (Agoura Hills, California) |
| ABSTRACT | Various embodiments relate to apparatuses and methods that can determine an amount of force on a tissue. An apparatus can include an optical fiber including a first end and a second end. An electronics module of the apparatus is coupled to the first end of the optical fiber. The electronics module can include a light emitter that can transmit light to the tissue over the optical fiber and a light sensor that can receive light over the optical fiber. The received light includes a component of the transmitted light reflected by the tissue. The electronics module can include a processor that can determine the amount of force on the tissue based on characteristic(s) of the reflected light. The apparatus can also include an end cap coupled to the second end of the optical fiber. The end cap can introduce the transmitted light into the tissue and receive the reflected light. |
| FILED | Friday, January 10, 2020 |
| APPL NO | 16/739530 |
| ART UNIT | 2623 — Selective Visual Display Systems |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/16 (20130101) Electric Digital Data Processing G06F 3/014 (20130101) Original (OR) Class G06F 3/017 (20130101) G06F 3/0304 (20130101) G06F 3/0325 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11132437 | Bilzor |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Michael Bilzor (Millersville, Maryland) |
| ABSTRACT | Systems, methods, and devices are provided for eliminating binary-level exploitable vulnerabilities in computer systems, making the computer systems more secure. Embodiments of the present disclosure can improve security using a computer system that can force user applications to be interpreted high-level language code, permitting the implementation of several well-defined security mechanisms in the computer system. |
| FILED | Tuesday, January 29, 2019 |
| APPL NO | 16/260260 |
| ART UNIT | 2419 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 21/51 (20130101) Original (OR) Class G06F 21/62 (20130101) G06F 21/556 (20130101) G06F 2221/033 (20130101) G06F 2221/2113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11132445 | Aldridge et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hal A Aldridge (Raleigh, North Carolina); John T. Orr (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hal A Aldridge (Raleigh, North Carolina); John T. Orr (Raleigh, North Carolina) |
| ABSTRACT | A system and method for testing for software vulnerabilities within components installed within a compartmentalized testing environment is presented herein. The system allows software code to be run within a software simulation environment, providing representative signals, whether Radio Frequency, microwave, or other portions of the electromagnetic spectrum, to test signals to the component under test while its execution is monitored and controlled within the compartmentalized testing environment. The system and method is particularly effective for searching for and identifying vulnerabilities to combined Cyber/Electronic Warfare attacks. |
| FILED | Monday, June 04, 2018 |
| APPL NO | 15/996575 |
| ART UNIT | 2491 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 8/61 (20130101) G06F 11/3664 (20130101) G06F 11/3684 (20130101) G06F 11/3688 (20130101) G06F 11/3692 (20130101) G06F 21/577 (20130101) Original (OR) Class G06F 2221/033 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11132915 | McIver et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Stephen McIver (Oxnard, California); Nicholas Lombardo (Long Beach, California); Priya Malavia (Westlake Village, California) |
| ABSTRACT | An augmented reality (AR) system for field training. The AR system may comprise: user platform sensors for obtaining user platform data associated with geolocation/orientation/movement of a user platform; a weapon simulator configured for haptic feedback and comprising weapon sensors for obtaining weapon data associated with muzzle orientation and trigger actuation of the weapon simulator, a head-worn display device for depicting AR graphic elements associated with training simulation data; target platform sensors for obtaining target platform data associated with geolocation/orientation/movement of a target platform; a microcontroller for packetizing the target platform data for wireless transmission; a computer system for generating the training simulation data based on the user platform data, weapon data, and target platform data; and transceivers for providing wireless communication between the computer system and microcontroller. The AR graphic elements may provide visual indications of the training simulation data, including severity and location of a projectile impact. |
| FILED | Wednesday, January 23, 2019 |
| APPL NO | 16/254673 |
| ART UNIT | 2175 — Graphical User Interface and Document Processing |
| CURRENT CPC | Weapon Sights; Aiming F41G 3/26 (20130101) Optical Elements, Systems, or Apparatus G02B 27/0172 (20130101) G02B 2027/0141 (20130101) Electric Digital Data Processing G06F 3/016 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 9/003 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11133388 | Joynt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Robert J. Joynt (Madison, Wisconsin); Mark G. Friesen (Middleton, Wisconsin); Mark A. Eriksson (Madison, Wisconsin); Susan Nan Coppersmith (Madison, Wisconsin); Donald E. Savage (Madison, Wisconsin) |
| ABSTRACT | Semiconductor heterostructures, methods of making the heterostructures, and quantum dots and quantum computation devices based on the heterostructures are provided. The heterostructures include a quantum well of strained silicon seeded with a relatively low concentration of germanium impurities disposed between two quantum barriers of germanium or a silicon-germanium alloy. The quantum wells are characterized in that the germanium concentration in the wells has an oscillating profile that increases the valley splitting in the conduction band of the silicon quantum well. |
| FILED | Thursday, July 23, 2020 |
| APPL NO | 16/936697 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Alloys C22C 28/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/151 (20130101) H01L 29/165 (20130101) Original (OR) Class H01L 29/0665 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11133452 | Chang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Josephine B. Chang (Bedford Hills, New York); Gerald W. Gibson (Danbury, Connecticut); Mark B. Ketchen (Hadley, Massachusetts) |
| ABSTRACT | A technique relates to a trilayer Josephson junction structure. A dielectric layer is on a base electrode layer that is on a substrate. A counter electrode layer is on the dielectric layer. First and second counter electrodes are formed from the counter electrode layer. First and second dielectric layers are formed from the dielectric layer. First and second base electrodes are formed from base electrode layer. The first counter electrode, first dielectric layer, and first base electrode form a first stack. The second counter electrode, second dielectric layer, and second base electrode form a second stack. A shunting capacitor is between first and second base electrodes. An ILD layer is deposited on the substrate, the first and second counter electrodes, and the first and second base electrodes. A contact bridge connects the first and second counter electrodes. An air gap is formed underneath the contact bridge by removing ILD. |
| FILED | Tuesday, May 21, 2019 |
| APPL NO | 16/417711 |
| ART UNIT | 2892 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/18 (20130101) H01L 28/40 (20130101) H01L 39/025 (20130101) H01L 39/223 (20130101) Original (OR) Class H01L 39/2493 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11133521 | Platt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Solid Power, Inc. (Louisville, Colorado) |
| ASSIGNEE(S) | Solid Power, Inc. (Louisville, Colorado) |
| INVENTOR(S) | Heather A. S. Platt (Golden, Colorado); Brandon Kelly (Longmont, Colorado); Joshua Buettner-Garrett (Littleton, Colorado) |
| ABSTRACT | Described herein are various embodiments of binder and slurry compositions and methods of making a solid-state battery therefrom. An solid-state electrochemical cell may include a first electrode substrate with a separator layer that is continuously interleaved in an alternating pattern with a second electrode substrate. A method of making a solid-state electrochemical cell may include applying a separator layer to a first electrode substrate and continuously interleaving folded portions of the first electrode substrate with alternating folded portions of a second electrode substrate to form an electrochemical cell. |
| FILED | Friday, April 08, 2016 |
| APPL NO | 15/565370 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 75/14 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/13 (20130101) H01M 4/622 (20130101) H01M 10/0431 (20130101) Original (OR) Class H01M 10/0525 (20130101) H01M 10/0583 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11133588 | Matos et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Randy Matos (Miami, Florida); Nezih Pala (Miami, Florida) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida) |
| INVENTOR(S) | Randy Matos (Miami, Florida); Nezih Pala (Miami, Florida) |
| ABSTRACT | Ultra-reconfigurable reflectarrays using vanadium dioxide (VO2) are provided, as well as methods of fabricating and using the same. The ultra-reconfigurable reflectarrays operate based on the unique phase-change properties of VO2, by including a heating element configured to heat desired areas of a VO2 layer/reflector, such that the VO2 reflector/layer can be reconfigured to have a desired pattern heated (and therefore changed to a conducting state) at a given time, with a good spatial resolution of the desired pattern. |
| FILED | Monday, March 08, 2021 |
| APPL NO | 17/194924 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 3/34 (20130101) H01Q 3/46 (20130101) Original (OR) Class H01Q 15/148 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11133637 | Helle |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Michael H. Helle (Arlington, Virginia) |
| ABSTRACT | A laser architecture for selectively producing short high-energy laser pulses having octave-spanning, continuous tunability. Two oppositely chirped pulses are used in combination with a pair of tunable pulse stretcher/compressors to produce a short, high-energy, tunable, broadband pulse. |
| FILED | Thursday, October 24, 2019 |
| APPL NO | 16/662166 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/39 (20130101) G02F 1/392 (20210101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0057 (20130101) Original (OR) Class H01S 3/0085 (20130101) H01S 3/1106 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11133640 | Anderson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Timothy C. Anderson (McKinney, Texas); Adam R. Girard (Blue Ridge, Texas) |
| ABSTRACT | An apparatus includes a base that includes a raised surface and a first opening through the raised surface. The apparatus also includes a cover configured to be coupled to the base in order to form a cavity, where the cover includes a second opening through the cover. The raised surface is configured to allow passage of a first portion of optical energy through the first opening and to reflect a second portion of the optical energy. Portions of the cover and the base surrounding the cavity are configured to absorb the reflected second portion of the optical energy. The base may further include one or more baffles positioned around the raised surface, and/or the cover may further include one or more baffles positioned around the second opening. |
| FILED | Thursday, June 06, 2019 |
| APPL NO | 16/433077 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/02 (20130101) H01S 3/0071 (20130101) H01S 3/0407 (20130101) H01S 3/1103 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11130129 | Ball et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Cameron Scott Ball (Sunnyvale, California); Ronald F. Renzi (Rexford, New York); Robert Meagher (Mountain House, California) |
| ABSTRACT | The present invention relates to microfluidic check valves, as well as fluidic cartridges including such check valves. In particular examples, the check valve includes a pre-stressed spring formed from a planar substrate. Various characteristics of the valves, such as size, profile, opening pressure, etc., can be tuned to provide desired performance when employed within a fluidic cartridge. |
| FILED | Wednesday, October 09, 2019 |
| APPL NO | 16/597292 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502707 (20130101) B01L 3/502715 (20130101) B01L 3/502738 (20130101) Original (OR) Class B01L 2200/10 (20130101) B01L 2200/12 (20130101) B01L 2300/049 (20130101) B01L 2300/0887 (20130101) B01L 2400/0487 (20130101) B01L 2400/0605 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 99/0015 (20130101) F16K 99/0057 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130131 | Deotte et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Joshua R. Deotte (Livermore, California); Sarah Baker (Dublin, California); Eric Duoss (Danville, California); Jennifer Marie Knipe (Oakland, California); Fang Qian (Santa Cruz, California); Samantha Ruelas (Newberry Springs, California) |
| ABSTRACT | An engineered unit cell is disclosed for flowing a fluid therethrough in three dimensions. The unit cell may have a substrate with a plurality of flow channels around and between struts formed within the substrate. The struts may each be formed with a desired shape and orientation within the substrate to achieve a desired degree of fluid flow through the flow channels, in each of one of three dimensions, through the unit cell. |
| FILED | Thursday, September 26, 2019 |
| APPL NO | 16/584460 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 3/502746 (20130101) Original (OR) Class B01L 2300/0874 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130288 | Moran |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Bryan D. Moran (Pleasanton, California) |
| ABSTRACT | The present disclosure relates to a digital light projector (DLP) system which has first and second light sources. The first optical source may generate a first beam at a first wavelength which causes polymerization of a photopolymerizable resist. The second optical source may generate a second beam at a second wavelength different from the first wavelength, and where the second beam inhibits polymerization of the photopolymerizable resist. A digital micromirror device (DMD) is included which has a plurality of micromirrors and is configured to be illuminated by the first and second beams and to generate a pattern on the micromirrors which has light from the first and second light wavelengths controlled by the micromirror position. The first light image causes polymerization of a first portion of the photopolymerizable resist, while the second image inhibits polymerization of a second portion of the photopolymerizable resist. |
| FILED | Wednesday, June 27, 2018 |
| APPL NO | 16/020529 |
| ART UNIT | 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/268 (20170801) Original (OR) Class B29C 64/277 (20170801) B29C 64/393 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) B33Y 50/02 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130295 | Rodgers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GM Global Technology Operations LLC (Detroit, Michigan) |
| ASSIGNEE(S) | GM Global Technology Operations LLC (Detroit, Michigan) |
| INVENTOR(S) | William R. Rodgers (Bloomfield Township, Michigan); Venkateshwar R. Aitharaju (Troy, Michigan) |
| ABSTRACT | Presented are manufacturing control systems for fabricating composite-material structures, methods for making/operating such systems, and resin transfer molding techniques for ameliorating race-tracking effects in fiber-reinforced polymer panels. A method for forming a composite-material construction includes confirming, via a system electronic control unit (ECU), that a fiber-based preform is placed in a mold cavity and that opposing mold segments of the molding apparatus are sealed together. A filler, such as a compressible bladder, a cluster of spring-biased pins, or a spray-chopped fiber bed, is introduced into a void between the fiber-based preform and a tool face of one mold segment to thereby eliminate an unwanted resin race track. The system ECU commands a resin pump to inject resin through a primary gate of the molding apparatus and into the mold cavity to thereby impregnate the fiber-based preform with the resin. One or more vents operate to evacuate air from the mold. |
| FILED | Friday, January 25, 2019 |
| APPL NO | 16/257801 |
| ART UNIT | 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 51/20 (20130101) B29C 70/48 (20130101) B29C 70/443 (20130101) Original (OR) Class Pulse Technique H03K 19/1733 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130788 | Hagen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Andrew R. Hagen (Oakland, California); Cheryl A. Kerfeld (Walnut Creek, California); Nancy B. Sloan (Berkeley, California); Markus Sutter (Oakland, California); Bryan H. Ferlez (Haslett, Michigan) |
| ABSTRACT | The present invention provides for a fusion protein comprising (1) a bacterial microcompartment (BMC) shell protein comprising one or more subunit, and (2) a first component of a specific-binding pair, operably linked to the BMC shell protein such that the first component faces (i) a lumen (inside) side, or (ii) outside of a BMC shell formed incorporating the fusion protein and the fusion protein does not disrupt or prevent the folding of the BMC shell protein or the ability of the BMC shell protein to integrate with other BMC shell proteins into a BMC shell; wherein the first component is capable of forming a stable or irreversible interaction with a second component of the specific-binding pair. |
| FILED | Tuesday, May 14, 2019 |
| APPL NO | 16/412133 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Separation B01D 15/363 (20130101) B01D 15/3804 (20130101) Peptides C07K 1/22 (20130101) C07K 14/195 (20130101) Original (OR) Class C07K 14/315 (20130101) C07K 2319/70 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131167 | Su et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Jiann-Cherng Su (Albuquerque, New Mexico); Stephen Buerger (Albuquerque, New Mexico); Anirban Mazumdar (Albuquerque, New Mexico); Adam Foris (Albuquerque, New Mexico) |
| ABSTRACT | Drilling tools are frequently subject to rotation with respect to the central drilling axis caused by torque. A mechanical linkage can be configured to apply force that is proportional to the weight-on-bit on the borehole surface while transmitting axial loads used to generate weight-on-bit. The device can be used to manage drill string twist that could lead to drilling dysfunctions. |
| FILED | Friday, November 10, 2017 |
| APPL NO | 15/809639 |
| ART UNIT | 3676 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 4/18 (20130101) E21B 17/02 (20130101) E21B 17/10 (20130101) E21B 17/1057 (20130101) E21B 17/1078 (20130101) E21B 43/106 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131407 | Dannemann et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | William Jackson Dannemann (San Francisco, California); Keir Christopher Gonyea (Dublin, California) |
| ABSTRACT | An apparatus for providing a preload to mated pipes including a ring-shaped body formed by a sidewall and an attachment structure on a portion of the body. The ring-shaped body includes an aperture that extends through the sidewall. The attachment structure corresponds to an attachment portion of a pipe in the mated pipes and the attachment structure enables removable fastening of the body to the pipe. The apparatus may further include an adjustable preload mechanism that can be removably attached to the body to hold the body in a preloaded position. The preload mechanism can be adjusted to release a portion of the preload held by the body. |
| FILED | Monday, September 30, 2019 |
| APPL NO | 16/588365 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 15/006 (20130101) F16L 15/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131441 | Gladden et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Glint Photonics, Inc. (Burlingame, California) |
| ASSIGNEE(S) | Glint Photonics, Inc. (Burlingame, California) |
| INVENTOR(S) | Christopher Gladden (San Mateo, California); Andrew Kim (San Jose, California); Peter Kozodoy (Palo Alto, California); Barbara Kruse (San Francisco, California) |
| ABSTRACT | A luminaire for providing configurable static lighting or dynamically-adjustable lighting. The luminaire uses an array of focusing elements that act on light provided via a corresponding array of sources or via an edge-lit lightguide. Designs are provided for adjusting the number of distinct beams produced by the luminaire, as well as the angular width, angular profile, and pointing angle of the beams. Designs are also provided for systems utilizing the adjustable luminaires in various applications. |
| FILED | Wednesday, October 07, 2020 |
| APPL NO | 17/065357 |
| ART UNIT | 2875 — Optics |
| CURRENT CPC | Non-electric Light Sources Using Luminescence; Light Sources Using Electrochemiluminescence; Light Sources Using Charges of Combustible Material; Light Sources Using Semiconductor Devices as Light-generating Elements; Light Sources Not Otherwise Provided for F21K 9/61 (20160801) Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for F21V 5/007 (20130101) F21V 7/0008 (20130101) F21V 14/06 (20130101) Original (OR) Class F21V 17/02 (20130101) Indexing Scheme Associated With Subclasses F21K, F21L, F21S and F21V, Relating to the Form or the Kind of the Light Sources or of the Colour of the Light Emitted F21Y 2105/00 (20130101) F21Y 2115/10 (20160801) Optical Elements, Systems, or Apparatus G02B 3/0006 (20130101) G02B 6/005 (20130101) G02B 6/0036 (20130101) G02B 6/0055 (20130101) G02B 19/0028 (20130101) G02B 19/0066 (20130101) G02B 26/08 (20130101) G02B 26/0875 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131502 | Kisner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Roger A. Kisner (Knoxville, Tennessee); Christi R. Johnson (Kingston, Tennessee); Frederick K. Reed (Oak Ridge, Tennessee) |
| ABSTRACT | A system for heating a fluid and an electromagnetic acoustic transducer EMAT system is provided. Both systems have a drive circuit. The amount of heat and the amplitude (and acceleration) of the vibrations is respectively controllable by controlling an input to a terminal of a switch. The heating system comprises a porous graphite foam conductor which is exposed to an electromagnetic field generated by an oscillating circuit. When exposed, the foam conductor conducts induced electric current which heats the same and a fluid in contact with the conductor. The EMAT system comprises at least one magnet configured to generate a static magnetic field, an oscillating circuit and a working element. The working element, when exposed to the static magnetic field and the electromagnetic field produced by the oscillating circuit, vibrates against a load. The vibrations dry the load. |
| FILED | Tuesday, August 14, 2018 |
| APPL NO | 16/103340 |
| ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Drying Solid Materials or Objects by Removing Liquid Therefrom F26B 3/20 (20130101) F26B 5/02 (20130101) Original (OR) Class F26B 23/10 (20130101) F26B 25/02 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 5/005 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 1/0219 (20130101) H05B 1/0225 (20130101) H05B 1/0244 (20130101) H05B 6/108 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131506 | Coteus et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Paul W. Coteus (Yorktown, New York); Shawn A. Hall (Pleasantville, New York); Mark D. Schultz (Ossining, New York); Todd E. Takken (Brewster, New York); Shurong Tian (Mount Kisco, New York) |
| ABSTRACT | An method for forming a cooling apparatus for cooling an electronic component. The apparatus has a planar top member of a thermal energy conductive material and a parallel planar bottom member of the material, the planar bottom member including a surface having regions configured for heat exchange contact with the electronic component. The planar top member has a plurality of stamped indent formations at a plurality of locations, each indent formation providing a contact surface such that the planar top member is affixed to the bottom member by braze or solder at each contact surface. Alternatively, the planar bottom member also has a plurality of stamped indent formations in alignment with indent formations of the top member. The planar top member is affixed to the bottom member by brazing or soldering each respective contact surface of an indent formation of the planar top member to an opposing contact surface of a corresponding indent formation of the parallel planar bottom member. |
| FILED | Friday, January 25, 2019 |
| APPL NO | 16/257584 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Working or Processing of Sheet Metal or Metal Tubes, Rods or Profiles Without Essentially Removing Material; Punching Metal B21D 53/04 (20130101) B21D 53/022 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 1/0012 (20130101) B23K 1/0016 (20130101) Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 15/26 (20130101) B23P 2700/10 (20130101) Solar Heat Collectors; Solar Heat Systems F24S 10/506 (20180501) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 1/0308 (20130101) Original (OR) Class Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 3/02 (20130101) F28F 3/14 (20130101) F28F 3/044 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/4878 (20130101) H01L 21/4882 (20130101) H01L 23/473 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131530 | Wilkins |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Paul R. Wilkins (Oakland, California) |
| ABSTRACT | An opto-thermal laser detonator uses resonantly absorptive tuned nano-material associated with secondary explosives for optical absorption and initiation by an integral laser diode. The opto-thermal laser detonator includes main explosive material; resonantly absorptive tuned nano-material; secondary explosive material, wherein the resonantly absorptive tuned nano-material and the secondary explosive material are associated to form associated material made of the resonantly absorptive tuned nano-material and the secondary explosive material; and a laser diode operatively connected to the associated material, wherein the laser diode initiates the associated material which in turn initiates the main explosive material. |
| FILED | Monday, January 29, 2018 |
| APPL NO | 15/882172 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 3/11 (20130101) F42B 3/113 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131628 | O'Rourke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SAVANNAH RIVER NUCLEAR SOLUTIONS, LLC (Aiken, South Carolina) |
| ASSIGNEE(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
| INVENTOR(S) | Patrick E. O'Rourke (Martinez, Georgia); Kimberly Alicia Strange Fessler (Aiken, South Carolina); Nicholas F. Deroller (Aiken, South Carolina); Steven M. Serkiz (Aiken, South Carolina) |
| ABSTRACT | Disclosed are spectroscopy systems and methods. A spectroscopy system can include a reference cell and a multi-pass sample cell. The reference arm can include an etalon and a reference cavity containing a reference gas. A system can include a fractional sublimation cold trap. Detectors of the reference and sample arms can detect both intensity and absorption spectra of impinging beams. A frequency calibration based on a reference absorption spectra can be used to analyze a sample absorption spectrum. The analysis can provide information regarding an absorption band shift of the sample absorption spectrum, said shift being related to the isotope concentration of the sample. |
| FILED | Tuesday, May 12, 2020 |
| APPL NO | 16/872533 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4022 (20130101) G01N 21/031 (20130101) G01N 21/39 (20130101) Original (OR) Class G01N 21/255 (20130101) G01N 21/0332 (20130101) G01N 2021/396 (20130101) G01N 2021/3107 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131648 | Cao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Energy, United States Department of (Washington, District of Columbia) |
| ASSIGNEE(S) | U.S. Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Guoping Cao (Idaho Falls, Idaho); Shelly X. Li (Idaho Falls, Idaho); Steven Herrmann (Idaho Falls, Idaho); Brenda Serrano-Rodriguez (Spring Lake, North Carolina) |
| ABSTRACT | According to one aspect of the invention, a potentiometric sensor having a cathode and an anode. The cathode is configured to provide a summary voltage representative of at least two voltage points. The anode is configured to provide a first voltage. The cathode is in communication with the anode by a first electrolyte forming an open circuit having an open circuit potential. Within the first electrolyte is a concentration of a target ion. The open circuit potential mathematically corresponds to the concentration of the target ion. |
| FILED | Thursday, June 20, 2019 |
| APPL NO | 16/447028 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/30 (20130101) G01N 27/40 (20130101) G01N 27/301 (20130101) G01N 27/403 (20130101) G01N 27/4161 (20130101) Original (OR) Class G01N 33/205 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11132300 | Loh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Advanced Micro Devices, Inc. (Sunnyvale, California) |
| ASSIGNEE(S) | ADVANCED MICRO DEVICES, INC. (Sunnyvale, California) |
| INVENTOR(S) | Gabriel H. Loh (Bellevue, Washington); James M. O'Connor (Austin, Texas) |
| ABSTRACT | A system includes a device coupleable to a first memory. The device includes a second memory to cache data from the first memory. The second memory is to store a set of compressed pages of the first memory and a set of page descriptors. Each compressed page includes a set of compressed data blocks. Each page descriptor represents a corresponding page and includes a set of location identifiers that identify the locations of the compressed data blocks of the corresponding page in the second memory. The device further includes compression logic to compress data blocks of a page to be stored to the second memory and decompression logic to decompress compressed data blocks of a page accessed from the second memory. |
| FILED | Thursday, July 11, 2013 |
| APPL NO | 13/939380 |
| ART UNIT | 2137 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 12/023 (20130101) G06F 12/0868 (20130101) Original (OR) Class G06F 2212/401 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
11133170 — Atmospheric-pressure ionization and fragmentation of molecules for structural elucidation
| US 11133170 | Shelley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana); Kent State University (Kent, Ohio) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana); Kent State University (Kent, Ohio) |
| INVENTOR(S) | Jacob T. Shelley (Troy, New York); Kelsey L. Williams (Kent, Ohio); Gary M. Hieftje (Bloomington, Indiana); Andrew J. Schwartz (Williamsville, New York) |
| ABSTRACT | A solution-cathode glow discharge mass spectrometry (SCGD-MS) apparatus comprises a SCGD source and a mass spectrometer. The SCGD source may comprise conductive rods, a power source, and a capillary. A method for ionizing an analyte comprises flowing an electrically conductive liquid onto a conductive rod, applying an electric potential to a second conductive rod such that a plasma discharge forms between the first conductive rod and the electrically conductive liquid to produce ions, and separating the ions in a mass spectrometer. The analyte may be a polypeptide that may be contacted with trypsin. The analyte may be a solid, liquid, gas, chemical complex, or ion in solution. The method may comprise sequencing the polypeptide. |
| FILED | Wednesday, August 19, 2020 |
| APPL NO | 16/997061 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/67 (20130101) G01N 27/68 (20130101) G01N 27/622 (20130101) G01N 30/726 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 13/16 (20130101) H01J 15/00 (20130101) H01J 37/04 (20130101) H01J 37/32055 (20130101) H01J 37/32935 (20130101) H01J 37/32981 (20130101) H01J 49/12 (20130101) H01J 49/145 (20130101) Original (OR) Class H01J 49/167 (20130101) H01J 49/168 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11133190 | Harrison et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Sara E. Harrison (Fremont, California); Clint Frye (Livermore, California); Rebecca J. Nikolic (Oakland, California); Qinghui Shao (Fremont, California); Lars F. Voss (Livermore, California) |
| ABSTRACT | According to one embodiment, a method includes performing a plasma etching process on a masked III-V semiconductor, and forming a passivation layer on etched portions of the III-V semiconductor. The passivation layer includes at least one of a group III element and/or a metal from the following: Ni, Cr, W, Mo, Pt, Pd, Mg, Ti, Zr, Hf, Y, Ta, and Sc. |
| FILED | Friday, May 04, 2018 |
| APPL NO | 15/971999 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/308 (20130101) H01L 21/02057 (20130101) H01L 21/02178 (20130101) H01L 21/02241 (20130101) H01L 21/02274 (20130101) H01L 21/3081 (20130101) H01L 21/30621 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11133433 | Husko |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Chad Husko (Wauconda, Illinois) |
| ABSTRACT | A semiconductor optical device is comprised of a phonon donating material structurally connected to an indirect bandgap material to improve absorption and emission of light in the indirect bandgap material. An excitation energy source provides excitation radiation to the semiconductor optical device to excite electrons in the semiconductor optical device. Phonons from the phonon donating material present in the indirect bandgap material provide a mechanism for increased rates of electron-hole generation and recombination, and electrical leads provide an electrical connection to the semiconductor optical device. |
| FILED | Friday, January 24, 2020 |
| APPL NO | 16/751729 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/035209 (20130101) H01L 33/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11133530 | Zhu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wildcat Discovery Technologies, Inc (San Diego, California) |
| ASSIGNEE(S) | Wildcat Discovery Technologies, Inc. (San Diego, California) |
| INVENTOR(S) | Ye Zhu (San Diego, California); Gang Cheng (San Diego, California); Deidre Strand (San Diego, California); Jen-Hsien Yang (San Diego, California) |
| ABSTRACT | Additives to electrolytes that enable the formation of comparatively more robust SEI films on silicon anodes. The SEI films in these embodiments are seen to be more robust in part because the batteries containing these materials have higher coulombic efficiency and longer cycle life than comparable batteries without such additives. |
| FILED | Tuesday, April 30, 2019 |
| APPL NO | 16/399636 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/134 (20130101) H01M 10/0525 (20130101) H01M 10/0567 (20130101) Original (OR) Class H01M 10/0569 (20130101) H01M 2004/027 (20130101) H01M 2300/0025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11133757 | Lorimer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Spark Thermionics, Inc. (Emeryville, California) |
| ASSIGNEE(S) | Spark Thermionics, Inc. (Emeryville, California) |
| INVENTOR(S) | Adam Lorimer (Emeryville, California); Jared William Schwede (Emeryville, California) |
| ABSTRACT | A system for combined heat and electric power generation, preferably including a heat reservoir and one or more electric generators, each preferably including a heat source and an energy converter. A method for combined heat and electric power generation, preferably including activating an electric generator, deactivating the electric generator, and/or providing heat from a heat reservoir. |
| FILED | Monday, February 08, 2021 |
| APPL NO | 17/170748 |
| ART UNIT | 2832 — Semiconductors/Memory |
| CURRENT CPC | Electric Machines Not Otherwise Provided for H02N 10/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11133927 | Jenkins |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Christipher D. Jenkins (Albuquerque, New Mexico) |
| ABSTRACT | A moving target defense scheme for a serial communications system is disclosed herein. A bus controller generates and broadcasts a nonce to remote terminals over a bus. The bus controller and the remote terminals generate a randomized sequence based upon the nonce and a shared secret that is shared between the bus controller and the remote terminals. The bus controller broadcasts first messages over the bus on first addresses that are derived from first portions of the randomized sequence. The remote terminals listen for the first messages that are broadcast over the bus on the first addresses. The bus controller broadcasts a shift message that causes the remote terminals to listen for second messages that are broadcast over the bus on second addresses that are derived from second portions of the randomized sequence. |
| FILED | Thursday, March 14, 2019 |
| APPL NO | 16/353039 |
| ART UNIT | 2432 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 7/582 (20130101) G06F 13/1668 (20130101) G06F 13/4282 (20130101) G06F 21/602 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/085 (20130101) Original (OR) Class H04L 63/0428 (20130101) H04L 2209/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11129921 | Kaplan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
| ASSIGNEE(S) | Trustees of Tufts College (Medford, Massachusetts) |
| INVENTOR(S) | David L. Kaplan (Concord, Massachusetts); Ung-Jin Kim (Daejeon, South Korea); Jaehyung Park (Decatur, Georgia); Hyoung-Joon Jin (Seoul, South Korea) |
| ABSTRACT | The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels. |
| FILED | Wednesday, May 08, 2019 |
| APPL NO | 16/406538 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/38 (20130101) A61L 27/52 (20130101) A61L 27/56 (20130101) A61L 27/227 (20130101) Original (OR) Class A61L 27/3604 (20130101) A61L 2430/02 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 39/003 (20130101) B29C 39/203 (20130101) B29C 55/005 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 7/01 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2089/00 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2007/00 (20130101) B29L 2009/00 (20130101) Peptides C07K 14/43536 (20130101) C07K 14/43586 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/07 (20130101) C08J 3/075 (20130101) C08J 5/18 (20130101) C08J 9/26 (20130101) C08J 9/28 (20130101) C08J 9/0061 (20130101) C08J 2201/0444 (20130101) C08J 2201/0504 (20130101) C08J 2205/022 (20130101) C08J 2389/00 (20130101) Compositions of Macromolecular Compounds C08L 89/00 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0007 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 4/02 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/249921 (20150401) Y10T 442/10 (20150401) Y10T 442/60 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130847 | Zhou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Gongyao Zhou (Wilmington, Delaware); Steven K. Leist (Philadelphia, Pennsylvania); Daniel E. Hagaman (Cherry Hill, New Jersey); Haifeng Ji (Cherry Hill, New Jersey) |
| ABSTRACT | The present invention provides a 4D printed component that uses the photoisomerization stimulus as a method of activation. Other 4D printing methods use heat, moisture, a combination of heat and stress, and the heat from a light source as methods of activation. The present invention takes advantage of 3D printing capability and adds the capability of providing a printable material that dynamically changes shape over time when exposed to an external stimulus. The invention reduces the number of required 3D printed parts to create a moving object. This characteristic reduces the amount of onboard weight of the 3D printed components by reducing the number of parts required to create motion. The present invention removes the need for onboard sensors, processors, motors, power storage, etc. This characteristic will allow for manufacturing of, inter alia, novel medical devices, automated actuators, packaging, smart textiles, etc. |
| FILED | Wednesday, June 05, 2019 |
| APPL NO | 16/432664 |
| ART UNIT | 1796 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 70/00 (20141201) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/18 (20130101) Original (OR) Class C08J 2379/08 (20130101) C08J 2483/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131619 | Ozdemir et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Sahin Kaya Ozdemir (St. Louis, Missouri); Lan Yang (St. Louis, Missouri); Bo Peng (St. Louis, Missouri) |
| ABSTRACT | A system and method for engineering loss in a physical system by steering parameters of the physical system to the vicinity of an exceptional point is disclosed. In the vicinity of an exceptional point, localization of the fields helps to enhance any linear or nonlinear processes. As examples loss-induced transparency in the intracavity field intensities of coupled resonators, loss-induced suppression and enhancement of thermal nonlinearity in coupled resonators and loss-induced suppression and revival of Raman lasing in whispering-gallery-microcavities are demonstrated. |
| FILED | Wednesday, May 16, 2018 |
| APPL NO | 15/981228 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1434 (20130101) Original (OR) Class G01N 21/7746 (20130101) G01N 2021/655 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/88 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131631 | Howard et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF NOTRE DAME DU LAC (Notre Dame, Indiana) |
| ASSIGNEE(S) | UNIVERSITY OF NOTRE DAME DU LAC (Notre Dame, Indiana) |
| INVENTOR(S) | Scott S. Howard (Notre Dame, Indiana); Yide Zhang (Notre Dame, Indiana); Cody J. Smith (Notre Dame, Indiana) |
| ABSTRACT | A microscopy method and system includes obtaining a plurality of raw fluorescence images, respective ones of the plurality of raw fluorescence images obtained by exciting a sample using a light source at a respective irradiance value in a weak saturation region of the sample, and capturing the respective raw fluorescence image; applying a plurality of weights to the plurality of raw fluorescence images in a one-to-one correspondence so as to generate a plurality of weighted fluorescence images, wherein a respective weight is based on the respective irradiance value at which the corresponding raw fluorescence image was obtained; and linearly combining the plurality of weighted fluorescence images, thereby generating the output image having a resolution greater than a diffraction limit. Respective raw fluorescence images correspond to irradiance values different from one another. |
| FILED | Friday, December 28, 2018 |
| APPL NO | 16/757634 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 21/0072 (20130101) G02B 21/0076 (20130101) G02B 21/367 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131737 | Frank et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Lawrence R. Frank (San Diego, California); Vitaly L. Galinsky (San Diego, California) |
| ABSTRACT | A method and for estimating local diffusion anisotropy and global tractography within neural architecture from diffusion weighted magnetic resonance image (dMRI) data uses a computer processor to integrate a first dataset comprising standard single pulsed field gradient (sPFG) dMRI data with a second dataset comprising double pulsed field gradient (dPFG) dMRI data into a common coordinate system with the same spatial resolution. The resulting image includes integrated macroscopic and microscopic anisotropy and global tractography within the target volume. |
| FILED | Thursday, June 04, 2020 |
| APPL NO | 16/893344 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5608 (20130101) G01R 33/56341 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11132178 | Plusquellic |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | STC.UNM (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James Plusquellic (Albuquerque, New Mexico) |
| ABSTRACT | This disclosure describes techniques for analyzing statistical quality of bitstrings produced by a physical unclonable function (PUF). The PUF leverages resistance variations in the power grid wires of an integrated circuit. Temperature and voltage stability of the bitstrings are analyzed. The disclosure also describes converting a voltage drop into a digital code, wherein the conversion is resilient to simple and differential side-channel attacks. |
| FILED | Thursday, April 23, 2020 |
| APPL NO | 16/856887 |
| ART UNIT | 2182 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 7/588 (20130101) Original (OR) Class G06F 2207/58 (20130101) Ciphering or Deciphering Apparatus for Cryptographic or Other Purposes Involving the Need for Secrecy G09C 1/00 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/002 (20130101) H04L 9/0866 (20130101) H04L 2209/12 (20130101) H04L 2209/26 (20130101) Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 40/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11132441 | Denney et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kyle Denney (Miami, Florida); Enes Erdin (Miami, Florida); Leonardo Babun (Miami, Florida); A. Selcuk Uluagac (Miami, Florida); Kemal Akkaya (Miami, Florida) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida) |
| INVENTOR(S) | Kyle Denney (Miami, Florida); Enes Erdin (Miami, Florida); Leonardo Babun (Miami, Florida); A. Selcuk Uluagac (Miami, Florida); Kemal Akkaya (Miami, Florida) |
| ABSTRACT | Novel hardware-based frameworks and methods for the detection and inhibition or prevention of insider threats utilizing machine learning methods and data collection done at the physical layer are provided. Analysis is done on unknown USB-powered devices, such as a keyboard or mouse, introduced to a computing environment and, through the utilization of machine learning, the behavior of the unknown device is determined before it can potentially cause harm to the computing environment. |
| FILED | Friday, April 24, 2020 |
| APPL NO | 16/857401 |
| ART UNIT | 2497 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/55 (20130101) Original (OR) Class G06F 21/6218 (20130101) G06F 2221/034 (20130101) Computer Systems Based on Specific Computational Models G06N 5/003 (20130101) G06N 5/04 (20130101) G06N 20/20 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11132551 | Katoch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sameeksha Katoch (Tempe, Arizona); Pavan Turaga (Tempe, Arizona); Andreas Spanias (Tempe, Arizona); Cihan Tepedelenlioglu (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona) |
| INVENTOR(S) | Sameeksha Katoch (Tempe, Arizona); Pavan Turaga (Tempe, Arizona); Andreas Spanias (Tempe, Arizona); Cihan Tepedelenlioglu (Tempe, Arizona) |
| ABSTRACT | Various embodiments of a cyber-physical system for providing cloud prediction for photovoltaic array control are disclosed herein. |
| FILED | Friday, June 14, 2019 |
| APPL NO | 16/441939 |
| ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 17/16 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00697 (20130101) G06K 9/00718 (20130101) Original (OR) Class G06K 9/00744 (20130101) G06K 9/6202 (20130101) Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) Image Data Processing or Generation, in General G06T 7/246 (20170101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/385 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11133118 | Watkins et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | James Watkins (South Hadley, Massachusetts); Michael R. Beaulieu (Chicopee, Massachusetts); Nicholas R. Hendricks (South Deerfield, Massachusetts) |
| ABSTRACT | Aspects relate to patterned nanostructures having a feature size not including film thickness of below 5 microns. The patterned nanostructures are made up of nanoparticles having an average particle size of less than 100 nm. A nanoparticle composition, which, in some cases, includes a binder material, is applied to a substrate. A patterned mold used in concert with electromagnetic radiation function to manipulate the nanoparticle composition in forming the patterned nanostructure. In some embodiments, the patterned mold nanoimprints a suitable pattern on to the nanoparticle composition and the composition is cured through UV or thermal energy. Three-dimensional patterned nanostructures may be formed. A number of patterned nanostructure layers may be prepared and suitably joined together. In some cases, a patterned nanostructure may be formed as a layer that is releasable from the substrate upon which it is initially formed. Such releasable layers may, in turn, be arranged to form a three-dimensional patterned nanostructure in accordance with suitable applications. |
| FILED | Wednesday, May 22, 2013 |
| APPL NO | 13/900248 |
| ART UNIT | 1785 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/08 (20130101) Original (OR) Class H01B 3/10 (20130101) H01B 13/003 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0015 (20130101) H01L 51/442 (20130101) H01L 51/5209 (20130101) H01L 2251/5369 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/04 (20130101) H01M 4/0433 (20130101) H01M 6/40 (20130101) H01M 8/124 (20130101) H01M 8/1286 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/50 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11133160 | Holden et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THERMO FINNIGAN LLC (San Jose, California); THERMO FISHER SCIENTIFIC (BREMEN) GMBH (Bremen, Germany); BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); THERMO FISHER SCIENTIFIC (BREMEN) GMBH (Bremen, Germany); THERMO FINNIGAN LLC (San Jose, California) |
| INVENTOR(S) | Dustin D. Holden (Austin, Texas); Jens Griep-Raming (Bremen, Germany); Alexander A. Makarov (Bremen, Germany); Jennifer S. Brodbelt (Austin, Texas); Yevgeniy Zhuk (San Jose, California); Jae C. Schwartz (San Jose, California) |
| ABSTRACT | Systems, methods, and devices to dissociate ions using one or more light emitting diodes (LEDs). A mass spectrometer for ion dissociation includes an ion source for providing ions for dissociation, a mass analyzer, and a photodissociation (PD) device. The PD device includes an ion transport device. The ion transport device is configured perform one or more of: transporting the ions through the PD device, and trapping the ions within a region of the PD device. The PD device also includes one or more LEDs positioned to irradiate the ions in the PD device, resulting in fragmentation of the ions. |
| FILED | Friday, June 02, 2017 |
| APPL NO | 16/306238 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/14 (20130101) H01J 49/022 (20130101) H01J 49/0059 (20130101) Original (OR) Class H01J 49/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11133601 | Yoon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida); Electronics and Telecommunications Research Institute (ETRI) (Daejeon, South Korea) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida); Electronics and Telecommunications Research Institute (ETRI) (Daejeon, South Korea) |
| INVENTOR(S) | Yong Kyu Yoon (Gainesville, Florida); Seahee Hwangbo (Gainesville, Florida); Hae Yong Yang (Daejeon, South Korea) |
| ABSTRACT | Various examples are provided that are related to fractal-based reactive impedance surfaces. These surfaces allow for miniaturization of antennas. In one example, a fractal rectangular reactive impedance surface (FR-RIS) includes a plurality of fractal rectangular (FR) patches having an outer edge defined by a fractal rectangular pattern that is repeated along each side of inner FR patches of the plurality of FR patches. The fractal rectangular pattern of a FR patch matches with the fractal rectangular pattern of an adjacent FR patch. An antenna can include a planar antenna disposed over the FR-RIS. |
| FILED | Friday, April 14, 2017 |
| APPL NO | 16/092019 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/00 (20130101) H01Q 1/38 (20130101) H01Q 1/48 (20130101) H01Q 3/04 (20130101) H01Q 9/04 (20130101) H01Q 9/16 (20130101) H01Q 9/045 (20130101) H01Q 9/0407 (20130101) H01Q 9/0428 (20130101) H01Q 9/0442 (20130101) H01Q 11/10 (20130101) H01Q 13/10 (20130101) H01Q 15/0093 (20130101) H01Q 21/0025 (20130101) H01Q 21/065 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11133851 | Hokayem et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rimon Hokayem (Miami, Florida); Elias Alwan (Miami, Florida); John L. Volakis (Miami, Florida) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida) |
| INVENTOR(S) | Rimon Hokayem (Miami, Florida); Elias Alwan (Miami, Florida); John L. Volakis (Miami, Florida) |
| ABSTRACT | Systems and methods for beamforming based on mixing elements together instead of conventional phase shifting are provided. A beamformer can be used to cross-mix the elements with one another to compensate for delays in signal reception. By replacing phase shifters with mixers, the system becomes agnostic to frequency of operation and angle of arrival. |
| FILED | Tuesday, March 30, 2021 |
| APPL NO | 17/217520 |
| ART UNIT | 2843 — Semiconductors/Memory |
| CURRENT CPC | Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 5/16 (20130101) Antennas, i.e Radio Aerials H01Q 1/50 (20130101) Amplifiers H03F 3/19 (20130101) H03F 2200/294 (20130101) H03F 2200/451 (20130101) Transmission H04B 7/0617 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11129546 | Dietrich et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of Americas as represented by the Administrator of NASA (Washingon, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Daniel L. Dietrich (Westlake, Ohio); Jeffrey R. Juergens (Parma Heights, Ohio); Mark E. Lewis (Merritt Island, Florida); Nancy C. Piltch (Olmsted Falls, Ohio); Michael J. Lichter (Strongsville, Ohio); Russel W. Valentine (Wadsworth, Ohio); Dale M. Diedrick (Elyria, Ohio); Richard D Pettegrew (Parma Heights, Ohio); Peter M. Struk (Olmsted Township, Ohio) |
| ABSTRACT | A portable unit for metabolic analysis includes a manifold in fluid communication with a mouth of a test subject. A conduit extends from the manifold and defines a flow channel through which the breaths of the test subject travels. A carbon dioxide sensor is attached to the conduit. The carbon dioxide sensor includes an intermediate support housing enclosing a volume disposed along the flow channel to define a first part of the flow channel, an inner support housing attached to a first side of the intermediate support housing, a plurality of IR LEDs mounted to an interior surface of the inner support housing, an outer support housing attached to a second side of the intermediate support housing, and a photodetector attached to the outer support housing. The photodetector faces the flow channel and receives IR radiation emitted by the plurality of LEDs. |
| FILED | Monday, August 06, 2018 |
| APPL NO | 16/056153 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/08 (20130101) A61B 5/082 (20130101) A61B 5/083 (20130101) Original (OR) Class A61B 5/087 (20130101) A61B 5/097 (20130101) A61B 5/0836 (20130101) A61B 5/4836 (20130101) A61B 2010/0087 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/497 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130678 | Matter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | pH Matter, LLC (Columbus, Ohio) |
| ASSIGNEE(S) | Paul H. Matter (Columbus, Ohio) |
| INVENTOR(S) | Paul H. Matter (Columbus, Ohio); Michael G. Beachy (Gahanna, Ohio); James Gaydos (Hilliard, Ohio) |
| ABSTRACT | A novel carbon formation reactor for forming carbon from a carbon-bearing fluidic stream, and method of using the same, is described. The reactor uses a catalyst bearing surface placed within a heated zone in a carbon-bearing fluidic stream to form carbon, which can then be removed from the reactor, with the process repeatable to achieve high extraction efficiencies. |
| FILED | Thursday, July 20, 2017 |
| APPL NO | 15/654996 |
| ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/46 (20130101) B01D 53/76 (20130101) B01D 53/81 (20130101) B01D 53/96 (20130101) B01D 53/864 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/15 (20170801) C01B 32/16 (20170801) C01B 32/162 (20170801) C01B 32/164 (20170801) Original (OR) Class Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/283 (20130101) Acyclic or Carbocyclic Compounds C07C 1/12 (20130101) C07C 1/12 (20130101) C07C 9/04 (20130101) Apparatus for Enzymology or Microbiology; C12M 43/02 (20130101) C12M 43/06 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) Feeding Fuel to Combustion Apparatus F23K 5/002 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/36 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/582 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11130742 | Wohl, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Christopher J. Wohl, Jr. (Suffolk, Virginia); John W. Connell (Yorktown, Virginia); Emilie J. Siochi (Newport News, Virginia); Joseph G. Smith, Jr. (Smithfield, Virginia) |
| ABSTRACT | Copoly(imide oxetane) materials are disclosed that can exhibit a low surface energy while possessing the mechanical, thermal, chemical and optical properties associated with polyimides. The copoly(imide oxetane)s are prepared using a minor amount of fluorinated oxetane-derived oligomer with sufficient fluorine-containing segments of the copoly(imide oxetane)s migrate to the exterior surface of the polymeric material to yield low surface energies. Thus the coatings and articles of manufacture made with the copoly(imide oxetane)s of this invention are characterized as having an anisotropic fluorine composition. The low surface energies can be achieved with very low content of fluorinated oxetane-derived oligomer. The copolymers of this invention can enhance the viability of polyimides for many applications and may be acceptable where homopolyimide materials have been unacceptable. |
| FILED | Tuesday, April 21, 2020 |
| APPL NO | 16/854265 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Heterocyclic Compounds C07D 305/08 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/68 (20130101) C08G 65/16 (20130101) C08G 65/18 (20130101) C08G 65/322 (20130101) C08G 65/33389 (20130101) C08G 73/02 (20130101) C08G 73/105 (20130101) C08G 73/1042 (20130101) Compositions of Macromolecular Compounds C08L 67/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 179/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11131294 | Bauman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Steven W. Bauman (Cleveland, Ohio); Othmane Benafan (Middleburg Heights, Ohio) |
| ABSTRACT | A scalable plurality of shape memory alloy (SMA) elements are configured to provide a continuous rotation actuator system. The plurality of SMA elements are coupled to a Ring Gear element, as well as to a Sun Gear element and a provision for thermal cycle return assist of the SMA elements. A plurality of Transmission elements provide for controlled rotary actuation in a desired direction with lock capability that provides for continuous rotary motion even as the SMA elements undergo reciprocating rotary action during their thermal cycling without running into system component rotation limits. The innovation distinguishes over other innovative approaches by way of at least the Ring Gear element, the manner of lock control, and the return assist element. |
| FILED | Friday, January 24, 2020 |
| APPL NO | 16/751658 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 7/065 (20130101) Original (OR) Class Gearing F16H 1/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11132033 | Duva et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | HAMILTON SUNDSTRAND CORPORATION (Charlotte, North Carolina) |
| INVENTOR(S) | Conner Duva (Enfield, Connecticut); Chi Wan (South Windsor, Connecticut); Kevin Cremona (Westfield, Massachusetts) |
| ABSTRACT | A modular controller includes an enclosure having an interior, a motherboard with a signal trace and a power trace supported within the interior of the enclosure, and one or more control section. The control section includes one or more of an input power section, an electromagnetic interference section, a logic section, a control section, a output power section, and a signal section that is supported by the motherboard to selectively flow of electrical power through the power trace using a control signal carried by the signal trace. Electrical systems and methods of making modular controllers are also described. |
| FILED | Wednesday, January 16, 2019 |
| APPL NO | 16/249564 |
| ART UNIT | 2841 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 1/182 (20130101) Original (OR) Class G06F 13/4027 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 5/0026 (20130101) H05K 7/1459 (20130101) H05K 9/0022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 11129734 | Hansen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Department of Veterans Affairs (Washington, District of Columbia); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | U.S. Department of Veterans Affairs (Washington, District of Columbia); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Andrew H. Hansen (Apple Valley, Minnesota); Eric A. Nickel (Chicago, Illinois) |
| ABSTRACT | An ankle-foot prosthesis includes a foot plate, an ankle frame attached to the foot plate, a yoke pivotally connected to the ankle frame and including a member for attaching to a leg, a damper having a first end connected to the yoke and a second end connected to the ankle frame, and a control mechanism for switching the damper between low and high settings. |
| FILED | Tuesday, May 07, 2019 |
| APPL NO | 16/404777 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/6607 (20130101) Original (OR) Class A61F 2002/745 (20130101) A61F 2002/748 (20130101) A61F 2002/5006 (20130101) A61F 2002/6614 (20130101) A61F 2002/6642 (20130101) A61F 2002/30505 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11129808 | Patel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); THE USA GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS OFFICE OF THE GENERAL COUNSEL PSG IV (Washington, District of Columbia) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERRANS AFFAIRS OFFICE OF THE GENERAL COUNSEL (Washington, District of Columbia) |
| INVENTOR(S) | Niketa A. Patel (Land O' Lakes, Florida); Rekha S. Patel (Tampa, Florida); Robert Pleasants Sparks (Tampa, Florida); Wayne Charles Guida (Saint Pete Beach, Florida) |
| ABSTRACT | Provided herein are formulations that can contain an effective amount of a PKCδ inhibitor. Also provided herein are methods of inhibiting a PKCδ in a subject in need thereof, that can include the step of administering an effective amount of a compound that is capable of inhibiting a PKCδ. |
| FILED | Wednesday, March 15, 2017 |
| APPL NO | 16/085221 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/36 (20130101) A61K 31/357 (20130101) A61K 31/444 (20130101) A61K 31/517 (20130101) A61K 31/519 (20130101) A61K 31/4035 (20130101) Original (OR) Class A61K 31/4184 (20130101) A61K 31/4965 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11129854 | Frank et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia); Schepens Eye Research Institute (Boston, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Schepens Eye Research Institute (Boston, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Markus H. Frank (Cambridge, Massachusetts); Natasha Y. Frank (Cambridge, Massachusetts); Bruce Ksander (Boston, Massachusetts); Paraskevi Evi Kolovou (Boston, Massachusetts) |
| ABSTRACT | Various aspects and embodiments of the present invention are directed to methods of treating a subject having an ocular condition, methods of isolating ocular stem cells, methods of selecting and/or producing ocular grafts for transplantation, and methods of promoting ocular cell regeneration as well as to grafts and preparations containing isolated ocular stem cells characterized by the expression of ABCB5 on their cell surface. |
| FILED | Monday, October 30, 2017 |
| APPL NO | 15/796920 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0051 (20130101) A61K 35/30 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/3834 (20130101) A61L 27/3839 (20130101) A61L 2430/16 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0621 (20130101) C12N 5/0623 (20130101) C12N 5/0668 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11129825 | Jenkins |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Elysium Therapeutics, Inc. (Danville, California) |
| ASSIGNEE(S) | ELYSIUM THERAPEUTICS, INC. (Akron, Ohio) |
| INVENTOR(S) | Thomas E. Jenkins (Half Moon Bay, California) |
| ABSTRACT | The invention provides compositions and methods for the treatment or prevention of pain. The invention provides constructs whereby hydrolysis of the construct by a specified gastrointestinal enzyme directly, or indirectly, releases an opioid when taken orally as prescribed. The gastrointestinal enzyme mediated release of opioid from constructs of the invention is designed to be attenuated in vivo via a saturation or inhibition mechanism when overdoses are ingested. The invention further provides constructs that are highly resistant to oral overdose, chemical tampering, and abuse via non-oral routes of administration. |
| FILED | Tuesday, February 26, 2019 |
| APPL NO | 16/286096 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/485 (20130101) Original (OR) Class A61K 47/55 (20170801) A61K 47/61 (20170801) A61K 47/64 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11133521 | Platt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Solid Power, Inc. (Louisville, Colorado) |
| ASSIGNEE(S) | Solid Power, Inc. (Louisville, Colorado) |
| INVENTOR(S) | Heather A. S. Platt (Golden, Colorado); Brandon Kelly (Longmont, Colorado); Joshua Buettner-Garrett (Littleton, Colorado) |
| ABSTRACT | Described herein are various embodiments of binder and slurry compositions and methods of making a solid-state battery therefrom. An solid-state electrochemical cell may include a first electrode substrate with a separator layer that is continuously interleaved in an alternating pattern with a second electrode substrate. A method of making a solid-state electrochemical cell may include applying a separator layer to a first electrode substrate and continuously interleaving folded portions of the first electrode substrate with alternating folded portions of a second electrode substrate to form an electrochemical cell. |
| FILED | Friday, April 08, 2016 |
| APPL NO | 15/565370 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 75/14 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/13 (20130101) H01M 4/622 (20130101) H01M 10/0431 (20130101) Original (OR) Class H01M 10/0525 (20130101) H01M 10/0583 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Interior (DOI)
| US 11130910 | Rand et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Barry Rand (Princeton, New Jersey); Ross Kerner (Princeton, New Jersey); Zhengguo Xiao (Plainsboro, New Jersey) |
| ABSTRACT | Organic-inorganic perovskite nanoparticle compositions are described herein. In some embodiments, a nanoparticle composition comprises a layer of organic-inorganic perovskite nanocrystals, the organic-inorganic perovskite nanocrystals comprising surfaces associated with ligands of size unable to incorporate into octahedral corner sites of the perovskite crystal structure. |
| FILED | Wednesday, March 22, 2017 |
| APPL NO | 16/095579 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) Original (OR) Class C09K 11/025 (20130101) C09K 2211/10 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/14 (20130101) C30B 29/12 (20130101) C30B 29/60 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/2009 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/42 (20130101) H01L 51/0077 (20130101) H01L 51/4253 (20130101) H01L 51/5032 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Treasury (TREASURY)
| US 11129570 | Kron et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BioFluid Technology, Inc. (Bryn Mawr, Pennsylvania) |
| ASSIGNEE(S) | BioFluid Technology, Inc. (Bryn Mawr, Pennsylvania) |
| INVENTOR(S) | Reuben E Kron (Bryn Mawr, Pennsylvania); Stephen J Kron (Chicago, Illinois) |
| ABSTRACT | Provided are devices and methods suitable for immobilizing tissue and for use in non-invasive methods of assessing lower urinary tract symptoms as well as in surgical application. |
| FILED | Friday, August 17, 2018 |
| APPL NO | 16/104316 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/205 (20130101) A61B 5/208 (20130101) A61B 5/6834 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 11133452 | Chang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Josephine B. Chang (Bedford Hills, New York); Gerald W. Gibson (Danbury, Connecticut); Mark B. Ketchen (Hadley, Massachusetts) |
| ABSTRACT | A technique relates to a trilayer Josephson junction structure. A dielectric layer is on a base electrode layer that is on a substrate. A counter electrode layer is on the dielectric layer. First and second counter electrodes are formed from the counter electrode layer. First and second dielectric layers are formed from the dielectric layer. First and second base electrodes are formed from base electrode layer. The first counter electrode, first dielectric layer, and first base electrode form a first stack. The second counter electrode, second dielectric layer, and second base electrode form a second stack. A shunting capacitor is between first and second base electrodes. An ILD layer is deposited on the substrate, the first and second counter electrodes, and the first and second base electrodes. A contact bridge connects the first and second counter electrodes. An air gap is formed underneath the contact bridge by removing ILD. |
| FILED | Tuesday, May 21, 2019 |
| APPL NO | 16/417711 |
| ART UNIT | 2892 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/18 (20130101) H01L 28/40 (20130101) H01L 39/025 (20130101) H01L 39/223 (20130101) Original (OR) Class H01L 39/2493 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 11132358 | Beller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Charles E. Beller (Baltimore, Maryland); Kristen Maria Summers (Takoma Park, Maryland); Christopher F. Ackermann (Fairfax, Virginia); Michael Drzewucki (Woodbridge, Virginia); Andrew Doyle (Mount Rainier, Maryland) |
| ABSTRACT | A method includes searching an initial set of documents for an initial set of query names. Each query name of the initial set of query names is associated with at least one document of the initial set of documents. The method also includes prioritizing the initial set of query names based on at least one topic label. The method also includes searching an additional set of documents to generate candidate query names. The method also includes prioritizing the candidate query names based on the at least one topic label. The method further includes applying a temporal search filter to each candidate query name to determine whether the candidate query name was processed within a time frame. The method further includes performing disambiguation processing on each candidate query name not processed within the time frame. |
| FILED | Tuesday, February 19, 2019 |
| APPL NO | 16/279650 |
| ART UNIT | 2154 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/242 (20190101) Original (OR) Class G06F 16/2477 (20190101) G06F 40/295 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, September 28, 2021.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2021/details-patents-20210427.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page