FedInvent™ Patents

Patent Details for Tuesday, November 16, 2021 

This page was updated on Wednesday, November 17, 2021 at 05:41 AM GMT

Department of Health and Human Services (HHS) 

US 11172827 Motafakker-Fard et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Ali Motafakker-Fard (Revere, Massachusetts);  Paulino Vacas Jacques (Boston, Massachusetts);  Guillermo Tearney (Cambridge, Massachusetts);  Mireille Rosenberg (Brookline, Massachusetts)
ABSTRACT An apparatus can be provided according to certain exemplary embodiments. For example, the apparatus can include a waveguiding first arrangement providing at least one electromagnetic radiation. A configuration can be provided that receives and splits the at least one electromagnetic radiation into a first radiation and a second radiation. The apparatus can further include a waveguiding second arrangement which has a first waveguide and a second waveguide, whereas the first waveguide receives the first radiation, and the second waveguide receives the second radiation. The first arrangement, the second arrangement and the configuration can be housed in a probe.
FILED Tuesday, April 03, 2018
APPL NO 15/944555
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 1/07 (20130101)
A61B 5/0066 (20130101)
A61B 5/0075 (20130101)
A61B 5/0084 (20130101) Original (OR) Class
A61B 2562/0233 (20130101)
A61B 2576/00 (20130101)

Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 9/02091 (20130101)

Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/2823 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/55 (20130101)
G01N 21/474 (20130101)
G01N 21/4795 (20130101)
G01N 2021/4757 (20130101)
G01N 2021/4761 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11172893 Zhu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Lei Zhu (Hefei, China PRC);  Michael Joseph Petrongolo, Jr. (Sewell, New Jersey)
ABSTRACT Disclosed herein is a system and method, which utilize primary beam modulation to enable single-scan dual-energy CT (DECT) on a conventional CT scanner. An attenuation sheet with a spatially-varying pattern is placed between the x-ray source and the imaged object. During the CT scan, the modulator selectively hardens the x-ray beam at specific detector locations. Thus, this method simultaneously acquires high and low energy data at each projection angle. High and low energy CT images can then reconstructed from the projections via an iterative CT reconstruction algorithm, which accounts for the spatial modulation of the projected x-rays.
FILED Thursday, June 29, 2017
APPL NO 16/310930
ART UNIT 2884 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/025 (20130101) Original (OR) Class
A61B 6/032 (20130101)
A61B 6/4035 (20130101)
A61B 6/4078 (20130101)
A61B 6/4085 (20130101)
A61B 6/4208 (20130101)
A61B 6/4435 (20130101)
A61B 6/5229 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/04 (20130101)
G01N 23/046 (20130101)
G01N 23/083 (20130101)
G01N 2223/424 (20130101)

Image Data Processing or Generation, in General
G06T 11/003 (20130101)
G06T 2211/408 (20130101)
G06T 2211/424 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11172910 Greenleaf et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) James F. Greenleaf (Rochester, Minnesota);  Shigao Chen (Rochester, Minnesota);  Armando Manduca (Rochester, Minnesota);  Pengfei Song (Rochester, Minnesota)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S) James F. Greenleaf (Rochester, Minnesota);  Shigao Chen (Rochester, Minnesota);  Armando Manduca (Rochester, Minnesota);  Pengfei Song (Rochester, Minnesota)
ABSTRACT Methods for measuring mechanical properties of an object or subject under examination with an ultrasound system and using unfocused ultrasound energy are provided. Shear waves that propagate in the object or subject are produced by applying unfocused ultrasound energy to the object or subject, and measurement data is acquired by applying focused or unfocused ultrasound energy to at least one location in the object or subject at which shear waves are present Mechanical properties are then calculated from the acquired measurement data.
FILED Monday, February 27, 2012
APPL NO 14/001604
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0059 (20130101)
A61B 8/461 (20130101)
A61B 8/485 (20130101) Original (OR) Class
A61B 8/5223 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/17 (20130101)
G01N 29/075 (20130101)
G01N 29/221 (20130101)
G01N 29/2456 (20130101)
G01N 2291/0422 (20130101)
G01N 2291/02475 (20130101)
G01N 2291/02827 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/4814 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/52042 (20130101)
G01S 15/8927 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173053 Colvin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) WillowWood Global LLC (Mount Sterling, Ohio)
ASSIGNEE(S) WILLOWWOOD GLOBAL LLC (Mount Sterling, Ohio)
INVENTOR(S) James M. Colvin (Hilliard, Ohio);  Matthew M. Wernke (Tampa, Florida);  Stephen A. Byers (Dublin, Ohio);  Evandro M. Ficanha (Grove City, Ohio)
ABSTRACT A prosthetic foot structure includes a plate assembly having a toe portion and a heel portion. The plate assembly includes a first plate adjoining a second plate along a seam at which the first plate is bonded to the second plate. The seam has an end between the first and second plates, and the first plate is spaced from the second plate across a gap that reaches away from the end of the seam. An attachment structure attaches the first plate to second plate. The attachment structure has a composite composition including a resin material containing reinforcing fibers. The reinforcing fibers reach through the first plate, across the gap, and through the second plate.
FILED Wednesday, March 04, 2020
APPL NO 16/808796
ART UNIT 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/66 (20130101) Original (OR) Class
A61F 2002/6621 (20130101)
A61F 2002/6642 (20130101)
A61F 2002/6657 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173119 Fahmy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
U.S. Public Health Service (USPHS)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S) YALE UNIVERSITY (New Haven, Connecticut)
ASSIGNEE(S) Yale University (New Haven, Connecticut)
INVENTOR(S) Tarek M. Fahmy (New Haven, Connecticut);  Eric Stern (Jamaica Plain, Massachusetts);  Richard A. Flavell (Guillford, Connecticut);  Jason Park (New York, New York);  Alyssa Siefert (Naugatuck, Connecticut);  Stephen H. Wrzesinski (Slingerlands, New York)
ABSTRACT A “nanolipogel” is a delivery vehicle including one or more lipid layer surrounding a hydrogel core, which may include an absorbent such as a cyclodextrin or ion-exchange resin. Nanolipogels can be constructed so as to incorporate a variety of different chemical entities that can subsequently be released in a controlled fashion. These different incorporated chemical entities can differ dramatically with respect to size and composition. Nanolipogels have been constructed to contain co-encapsulated proteins as well as small hydrophobic drugs within the interior of the lipid bilayer. Agents incorporated within nanolipogels can be released into the milieu in a controlled fashion, for example, nanolipogels provide a means of achieving simultaneous sustained release of agents that differ widely in chemical composition and molecular weight. Additionally, nanolipogels can favorably modulate biodistribution.
FILED Thursday, December 12, 2019
APPL NO 16/711591
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/127 (20130101) Original (OR) Class
A61K 9/1271 (20130101)
A61K 9/1273 (20130101)
A61K 9/1277 (20130101)
A61K 9/5153 (20130101)
A61K 31/343 (20130101)
A61K 38/1841 (20130101)
A61K 38/2013 (20130101)
A61K 47/24 (20130101)
A61K 47/40 (20130101)
A61K 47/58 (20170801)
A61K 47/6849 (20170801)
A61K 47/6937 (20170801)
A61K 47/6951 (20170801)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)

Peptides
C07K 16/2812 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173144 Shamloo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Mehrdad Shamloo (Stanford, California);  Alam Jahangir (San Jose, California);  Bitna Yi (San Mateo, California);  Andrew Kelley Evans (Essex Junction, Vermont);  Michael John Green (Half Moon Bay, California)
ABSTRACT Adrenergic receptor modulating compounds and methods of using the same are provided. Also provided are methods of treating a subject for a disease or condition associated with an adrenergic receptor including administering a therapeutically effective amount of the subject compound. Aspects of the disclosure include a method of modulating an inflammatory pathway in a cell, such as the production of TNF-alpha in the cell. The method can include contacting a cell with β1-selective adrenergic receptor modulating compound to selectively activate a cAMP pathway over a beta-arrestin pathway in the cell. Pharmaceutical compositions and kits which include the subject compounds are provided.
FILED Friday, May 12, 2017
APPL NO 16/099802
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/138 (20130101)
A61K 31/216 (20130101)
A61K 31/397 (20130101)
A61K 31/416 (20130101) Original (OR) Class
A61K 31/4453 (20130101)
A61K 31/5377 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 11/00 (20180101)
A61P 25/28 (20180101)
A61P 29/00 (20180101)
A61P 35/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173146 Wulff et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Heike Wulff (Davis, California);  Nichole Coleman (San Francisco, California);  Brandon M. Brown (Davis, California);  Aida Olivan-Viguera (Saragossa, Spain);  Ralf Kohler (Saragossa, Spain)
ABSTRACT Benzoxazole and indole type KCa3.1 activators as well as the therapeutic uses of such compounds in human or animal subjects and their use in ex vivo preservation of organs or tissues.
FILED Friday, April 24, 2015
APPL NO 15/306457
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/404 (20130101)
A61K 31/423 (20130101) Original (OR) Class
A61K 31/428 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173154 Marazzi
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Research Office (ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Centers of Excellence for Influenza Research and Response (CEIRR)
Center for Research on Influenza Pathogenesis (CRIP)
APPLICANT(S) ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York)
ASSIGNEE(S) ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York)
INVENTOR(S) Ivan Marazzi (New York, New York)
ABSTRACT A method of treating a disease, condition or state characterized by an exacerbated immune response is disclosed. The method of treatment can include topoisomerase I inhibitors and pharmaceutical compositions comprising topoisomerase I inhibitors, which can be administered alone or in combination with another therapeutic agent. The method can be used to treat a range of diseases, disorders, conditions and states, including but not limited to sepsis, acute liver failure, and endotoxic and/or exotoxic shock. These diseases, disorders, conditions and states can be caused by a variety of microorganisms and/or portions of microorganisms including but not limited to Ebola virus, Lassa virus, Influenza virus, Legionella, lipopolysaccharide (LPS), and bacterial endotoxins/exotoxins.
FILED Thursday, December 15, 2016
APPL NO 16/063009
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/05 (20130101)
A61K 31/473 (20130101)
A61K 31/4745 (20130101) Original (OR) Class
A61K 38/005 (20130101)
A61K 45/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173195 Nussenblatt et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Enzo Biochem, Inc. (New York, New York)
ASSIGNEE(S) Enzo Biochem, Inc. (New York, New York)
INVENTOR(S) Robert Nussenblatt (Bethesda, Maryland);  Baoying Liu (North Potomac, Maryland);  Lai Wei (Rockville, Maryland);  Elazar Rabbani (New York, New York);  James J. Donegan (Amesbury, Massachusetts)
ABSTRACT The invention provides immunomodulatory pharmaceutical compositions that include a synthetic peptide and transforming growth factor beta, (TGF-β).
FILED Tuesday, June 02, 2020
APPL NO 16/889838
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101)
A61K 39/0008 (20130101) Original (OR) Class
A61K 2039/577 (20130101)
A61K 2039/55583 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173198 Sun
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida)
ASSIGNEE(S) UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida)
INVENTOR(S) Xingmin Sun (Tampa, Florida)
ABSTRACT Described are immunogenic proteins against Clostridium difficile. Also described are compositions comprising the immunogenic proteins. Further described are methods of preventing or treating a Clostridium difficile infection in a subject in need thereof.
FILED Monday, February 10, 2020
APPL NO 16/786350
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/164 (20130101)
A61K 39/08 (20130101) Original (OR) Class
A61K 39/0275 (20130101)
A61K 2039/541 (20130101)
A61K 2039/543 (20130101)
A61K 2039/6037 (20130101)
A61K 2039/6068 (20130101)
A61K 2039/55561 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)

Peptides
C07K 14/33 (20130101)
C07K 14/255 (20130101)
C07K 19/00 (20130101)
C07K 2319/03 (20130101)
C07K 2319/55 (20130101)
C07K 2319/74 (20130101)

Enzymes
C12Y 204/00 (20130101)
C12Y 304/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173201 Volkmann et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Bavarian Nordic A/S (Kvistgaard, Denmark);  Janssen Vaccines and Prevention B.V. (Leiden, Netherlands);  The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethedsa, Maryland)
ASSIGNEE(S) Bavarian Nordic A/S (Kvistgaard, Denmark);  Janssen Vaccines and Prevention B.V. (Leiden, Netherlands);  The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Ariane Volkmann (Andechs, Germany);  Robin Steigerwald (Munich, Germany);  Ulrike Dirmeier (Starnberg, Germany);  Maria Grazia Pau (Leiden, Netherlands);  Benoit Christophe Stephan Callendret (The Hague, Netherlands);  Lucy A. Ward (Silver Spring, Maryland)
ABSTRACT The present invention provides compositions, vaccines and methods for inducing protective immunity against filovirus infection, particularly protective immunity against infection of one or more subtypes of Ebola viruses and Marburg virus.
FILED Thursday, October 17, 2019
APPL NO 16/655516
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101) Original (OR) Class
A61K 2039/545 (20130101)
A61K 2039/572 (20130101)
A61K 2039/575 (20130101)
A61K 2039/5254 (20130101)
A61K 2039/5256 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2710/10041 (20130101)
C12N 2710/24041 (20130101)
C12N 2760/14134 (20130101)
C12N 2760/14171 (20130101)
C12N 2760/14234 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173202 Oh et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) BAYLOR RESEARCH INSTITUTE (Dallas, Texas)
ASSIGNEE(S) Baylor Research Institute (Dallas, Texas)
INVENTOR(S) SangKon Oh (Baltimore, Maryland);  Dapeng Li (David, California)
ABSTRACT The present invention includes compositions and methods for making and using anti DC-ASGPR antibodies that can, e.g., activate DCs and other cells.
FILED Tuesday, April 02, 2019
APPL NO 16/372832
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/145 (20130101) Original (OR) Class
A61K 47/6849 (20170801)
A61K 51/1027 (20130101)
A61K 2039/5154 (20130101)

Peptides
C07K 14/005 (20130101)
C07K 14/37 (20130101)
C07K 14/195 (20130101)
C07K 14/405 (20130101)
C07K 14/435 (20130101)
C07K 16/28 (20130101)
C07K 2317/24 (20130101)
C07K 2317/33 (20130101)
C07K 2317/56 (20130101)
C07K 2317/74 (20130101)
C07K 2317/75 (20130101)
C07K 2317/92 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0639 (20130101)
C12N 7/00 (20130101)
C12N 2760/16122 (20130101)
C12N 2760/16134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173204 Callendret et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Janssen Vaccines and Prevention B.V. (Leiden, Netherlands);  Bavarian Nordic A/S (Kvistgaard, Denmark)
ASSIGNEE(S) Janssen Vaccines and Prevention B.V. (Leiden, Netherlands);  Bavarian Nordic A/S (Kvistgaard, Denmark)
INVENTOR(S) Benoit Christophe Stephan Callendret (The Hague, Netherlands);  Kerstin Luhn-Wegmann (Leiden, Netherlands)
ABSTRACT Compositions and methods are described for generating an improved effective immune response against an immunogen in humans. The enhanced immune response, is obtained by using an MVA vector as a prime, an adenovirus vector as a first boost, and an adenovirus vector as a second boost. The compositions and methods can be used to provide a protective immunity against a disease, such as an infection of one or more subtypes of Ebola and Marburg filoviruses, in humans.
FILED Friday, April 06, 2018
APPL NO 16/500567
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/235 (20130101) Original (OR) Class
A61K 2039/70 (20130101)
A61K 2039/545 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)
A61P 31/20 (20180101)
A61P 37/04 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173205 O'Reilly et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Memorial Sloan Kettering Cancer Center (New York, New York)
ASSIGNEE(S) Memorial Sloan Kettering Cancer Center (New York, New York)
INVENTOR(S) Richard J. O'Reilly (Roxbury, Connecticut);  Ekaterina Doubrovina (Bronx, New York);  Guenther Koehne (New York, New York);  Aisha N. Hasan (Blue Bell, Pennsylvania);  Susan E. Prockop (New York, New York)
ABSTRACT Disclosed herein are methods of selecting an allogeneic T cell line for therapeutic administration to a patient having or suspected of having a pathogen or cancer. Also disclosed are methods of selecting a donor from whom to derive an allogeneic T cell line for therapeutic administration to a patient having or suspected of having a pathogen or cancer.
FILED Wednesday, November 04, 2015
APPL NO 15/523544
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101)
A61K 39/0011 (20130101)
A61K 39/25 (20130101) Original (OR) Class
A61K 39/001153 (20180801)
A61K 2039/572 (20130101)
A61K 2039/5158 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6881 (20130101)
C12Q 2600/136 (20130101)
C12Q 2600/172 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/505 (20130101)
G01N 33/574 (20130101)
G01N 33/57407 (20130101)
G01N 2333/03 (20130101)
G01N 2333/05 (20130101)
G01N 2333/045 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 35/00 (20190201)
G16B 35/20 (20190201)
G16B 45/00 (20190201)

Computational Chemistry; Chemoinformatics; Computational Materials Science
G16C 20/60 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173210 Overstreet
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) Sonoran Biosciences, Inc. (Chandler, Arizona)
ASSIGNEE(S) Sonoran Biosciences, Inc. (Chandler, Arizona)
INVENTOR(S) Derek J. Overstreet (Chandler, Arizona)
ABSTRACT A polymer composition can include an aqueous vehicle and a temperature-responsive degradable polymer having a polymer including a LCST-imparting unit and a lactone-bearing unit including a pendent lactone group. The number of LCST-imparting units is greater than the number of lactone-bearing units. The temperature-responsive degradable polymer has an initial lower critical solution temperature (LCST) of 37° C. or below. The polymer composition can have a pH lower than 7.
FILED Friday, April 24, 2020
APPL NO 16/858479
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle
A61J 1/2096 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/06 (20130101)
A61K 31/435 (20130101)
A61K 31/702 (20130101)
A61K 31/7036 (20130101)
A61K 47/32 (20130101) Original (OR) Class

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 5/19 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 220/58 (20130101)
C08F 2800/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173211 Crew et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) ARVINAS OPERATIONS, INC. (New Haven, Connecticut);  YALE UNIVERSITY (New Haven, Connecticut)
ASSIGNEE(S) ARVINAS OPERATIONS, INC. (New Haven, Connecticut);  YALE UNIVERSITY (New Haven, Connecticut)
INVENTOR(S) Andrew P. Crew (Guilford, Connecticut);  Keith R. Hornberger (Southbury, Connecticut);  Jing Wang (Milford, Connecticut);  Saul Jaime-Figueroa (Morris Plains, New Jersey);  Hanqing Dong (Madison, Connecticut)
ABSTRACT The present disclosure relates to bifunctional compounds, which find utility as modulators of Rapidly Accelerated Fibrosarcoma (RAF, such as c-RAF, A-RAF and/or B-RAF; the target protein). In particular, the present disclosure is directed to bifunctional compounds, which contain on one end a Von Hippel-Lindau, cereblon, Inhibitors of Apotosis Proteins or mouse double-minute homolog 2 ligand which binds to the respective E3 ubiquitin ligase and on the other end a moiety which binds the target protein RAF, such that the target protein is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of target protein. The present disclosure exhibits a broad range of pharmacological activities associated with degradation/inhibition of target protein. Diseases or disorders that result from aggregation or accumulation of the target protein, or the constitutive activation of the target protein, are treated or prevented with compounds and compositions of the present disclosure.
FILED Saturday, September 07, 2019
APPL NO 16/563842
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/55 (20170801) Original (OR) Class

Heterocyclic Compounds
C07D 413/14 (20130101)
C07D 417/14 (20130101)
C07D 471/04 (20130101)
C07D 519/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173216 Roy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S) Subhojit Roy (Madison, Wisconsin);  Jichao Sun (Madison, Wisconsin)
ABSTRACT Described herein are CRISPR/Cas9 constructs designed for the C-terminal truncation of human amyloid precursor protein (APP) as well as methods of making and using such a construct. A Cas9 nuclease/gRNA ribonucleoprotein directs cleavage of an APP gene to provide a C-terminal truncated APP having a length of 659, 670, 676, or 686 amino acids, relative to the human or mouse APP sequence.
FILED Friday, January 18, 2019
APPL NO 16/251970
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 48/0008 (20130101)
A61K 48/0058 (20130101)
A61K 48/0066 (20130101) Original (OR) Class
A61K 48/0075 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/28 (20180101)

Peptides
C07K 14/4711 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/102 (20130101)
C12N 15/907 (20130101)
C12N 2310/20 (20170501)
C12N 2740/16043 (20130101)
C12N 2750/14143 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173227 Yang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania);  BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S) THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania);  BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Jian Yang (State College, Pennsylvania);  Kytai T. Nguyen (Grand Prairie, Texas);  Zhiwei Xie (State College, Pennsylvania)
ABSTRACT In one aspect, compositions and wound dressings are described herein. In some embodiments, a composition or wound dressing described herein comprises a mesh formed from a plurality of biodegradable polymer fibers; a first active agent dispersed in the biodegradable polymer fibers; a plurality of biodegradable polymer particles disposed in the mesh; and a second active agent dispersed in the biodegradable polymer particles. The particles can be disposed within the interiors of the fibers of the mesh or between the fibers of the mesh. In another aspect, a composition or wound dressing described herein comprises a first perforated mesh formed from a first plurality of biodegradable polymer fibers; and a second perforated mesh formed from a second plurality of biodegradable polymer fibers, wherein the second perforated mesh is disposed on the first perforated mesh in a stacked configuration and the first and second perforated meshes have different degrees of perforation.
FILED Wednesday, May 21, 2014
APPL NO 14/891862
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 15/26 (20130101)
A61L 15/26 (20130101)
A61L 15/28 (20130101)
A61L 15/28 (20130101)
A61L 15/28 (20130101)
A61L 15/44 (20130101)
A61L 15/64 (20130101)
A61L 15/225 (20130101) Original (OR) Class
A61L 15/425 (20130101)
A61L 31/06 (20130101)
A61L 31/06 (20130101)
A61L 31/16 (20130101)
A61L 31/042 (20130101)
A61L 31/042 (20130101)
A61L 31/042 (20130101)
A61L 31/129 (20130101)
A61L 31/129 (20130101)
A61L 31/129 (20130101)
A61L 31/129 (20130101)
A61L 31/129 (20130101)
A61L 31/146 (20130101)
A61L 31/148 (20130101)
A61L 2300/45 (20130101)
A61L 2300/252 (20130101)
A61L 2300/404 (20130101)
A61L 2300/414 (20130101)
A61L 2300/604 (20130101)
A61L 2300/624 (20130101)

Compositions of Macromolecular Compounds
C08L 1/26 (20130101)
C08L 1/26 (20130101)
C08L 1/26 (20130101)
C08L 5/08 (20130101)
C08L 5/08 (20130101)
C08L 5/08 (20130101)
C08L 67/04 (20130101)
C08L 67/04 (20130101)
C08L 71/02 (20130101)
C08L 71/02 (20130101)
C08L 71/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173278 Lederman et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland);  Henry Ford Health System (Detroit, Michigan)
ASSIGNEE(S) The USA, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland);  Henry Ford Health System (Detroit, Michigan)
INVENTOR(S) Robert J. Lederman (Chevy Chase, Maryland);  Toby Rogers (Washington, District of Columbia);  Nasser Rafiee (Andover, Maryland);  Adam B. Greenbaum (Detroit, Michigan);  William W. O'Neill (Grosse Point Farms, Michigan)
ABSTRACT Disclosed delivery catheters have a three-dimensional curvature that facilitates reaching the RAA from the inferior vena cava, positioning the distal end of the catheter generally parallel to the plane of the pericardial space at the puncture location within the RAA, orienting the puncturing device in a direction that avoids the right coronary artery, aorta, pulmonary artery, and other structures to prevent bystander injury to such structures, and provides sufficient rigidity to puncture through a wall of the RAA into the pericardial space.
FILED Monday, May 09, 2016
APPL NO 15/571342
ART UNIT 3783 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/00234 (20130101)
A61B 17/3415 (20130101)
A61B 17/12122 (20130101)
A61B 18/1492 (20130101)
A61B 2017/003 (20130101)
A61B 2017/00243 (20130101)
A61B 2017/00331 (20130101)
A61B 2017/22069 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 25/10 (20130101)
A61M 25/0041 (20130101) Original (OR) Class
A61M 25/0082 (20130101)
A61M 25/09041 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173305 Greenberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Second Sight Medical Products, Inc. (Sylmar, California)
ASSIGNEE(S) Second Sight Medical Products, Inc. (Sylmar, California)
INVENTOR(S) Robert Jay Greenberg (Los Angeles, California);  Kelly Hobart McClure (Simi Valley, California);  James S. Little (Arvada, Colorado);  Rongqing Dai (Valencia, California);  Arup Roy (Los Angeles, California);  Richard Agustin Castro (Santa Monica, California);  John Reinhold (Tarzana, California);  Kea-Tiong Tang (Hsinchu, Taiwan);  Sumit Yadav (Lake Forest, California);  Chunhong Zhou (San Diego, California);  David Daomin Zhou (Valencia, California);  Pishoy Maksy (Newport Beach, California)
ABSTRACT In electrically stimulating neural tissue it is important to prevent over stimulation and unbalanced stimulation, which would cause damage to the neural tissue, the electrode, or both. It is critical that neural tissue is not subjected to any direct current or alternating current above a safe threshold. Further, it is important to identify defective electrodes, as continued use may result in neural damage and further electrode damage. The present invention presents system and stimulator control mechanisms to prevent damage to neural tissue.
FILED Thursday, July 18, 2019
APPL NO 16/516046
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/00 (20130101)
A61N 1/08 (20130101)
A61N 1/0543 (20130101)
A61N 1/0551 (20130101)
A61N 1/3603 (20170801)
A61N 1/36046 (20130101) Original (OR) Class
A61N 1/36142 (20130101)
A61N 1/36185 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173306 Greenberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Second Sight Medical Products, Inc. (Sylmar, California)
ASSIGNEE(S) Second Sight Medical Products, Inc. (Sylmar, California)
INVENTOR(S) Robert Jay Greenberg (Los Angeles, California);  Kelly Hobart McClure (Simi Valley, California);  James S. Little (Arvada, Colorado);  Rongqing Dai (Valencia, California);  Arup Roy (Los Angeles, California);  Richard Agustin Castro (Santa Monica, California);  John Reinhold (Tarzana, California);  Kea-Tiong Tang (Hsinchu, Taiwan);  Sumit Yadav (Lake Forest, California);  Chunhong Zhou (San Diego, California);  David Daomin Zhou (Valencia, California);  Pishoy Maksy (Newport Beach, California)
ABSTRACT In electrically stimulating neural tissue it is important to prevent over stimulation and unbalanced stimulation, which would cause damage to the neural tissue, the electrode, or both. It is critical that neural tissue is not subjected to any direct current or alternating current above a safe threshold. Further, it is important to identify defective electrodes, as continued use may result in neural damage and further electrode damage. The present invention presents system and stimulator control mechanisms to prevent damage to neural tissue.
FILED Thursday, July 18, 2019
APPL NO 16/516078
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/00 (20130101)
A61N 1/08 (20130101)
A61N 1/0543 (20130101)
A61N 1/0551 (20130101)
A61N 1/3603 (20170801)
A61N 1/36046 (20130101) Original (OR) Class
A61N 1/36142 (20130101)
A61N 1/36185 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173487 Ros et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Alexandra Ros (Phoenix, Arizona);  Daihyun Kim (Mesa, Arizona);  Jinghui Luo (Covina, California)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S) Alexandra Ros (Phoenix, Arizona);  Daihyun Kim (Mesa, Arizona);  Jinghui Luo (Covina, California)
ABSTRACT Sub-micrometer bioparticles are separated by size in a microfluidic channel utilizing a ratchet migration mechanism. A structure within the microfluidic channel includes an array of micro-posts arranged in laterally shifted rows. Reservoirs are disposed at each end of the microfluidic channel. A biased AC potential is applied across the channel via electrodes immersed into fluid in each of the reservoirs to induce a non-uniform electric field through the microfluidic channel. The applied potential comprises a first waveform with a first frequency that induces electro-kinetic flow of sub-micrometer bioparticles in the microfluidic channel, and an intermittent superimposed second waveform with a higher frequency. The second waveform selectively induces a dielectrophoretic trapping force to selectively impart ratchet migration based on particle size for separating the sub-micrometer bioparticles by size in the microfluidic channel.
FILED Wednesday, December 19, 2018
APPL NO 16/226165
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/50273 (20130101)
B01L 3/502715 (20130101) Original (OR) Class
B01L 3/502753 (20130101)
B01L 3/502761 (20130101)
B01L 2200/0647 (20130101)
B01L 2200/0652 (20130101)
B01L 2300/0816 (20130101)
B01L 2400/086 (20130101)
B01L 2400/0406 (20130101)
B01L 2400/0415 (20130101)
B01L 2400/0424 (20130101)

Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields
B03C 5/005 (20130101)
B03C 5/026 (20130101)
B03C 5/028 (20130101)
B03C 2201/26 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 2001/4038 (20130101)
G01N 2015/0038 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173520 Ma et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Bo Ma (Palo Alto, California);  Kamyar Firouzi (Palo Alto, California);  Butrus T. Khuri-Yakub (Palo Alto, California);  Jose Joseph (Stanford, California)
ABSTRACT Aspects of this disclosure relate to driving a capacitive micromachined ultrasonic transducer (CMUT) with a pulse train of unipolar pulses. The CMUT may be electrically excited with a pulse train of unipolar pulses such that the CMUT operates in a continuous wave mode. In some embodiments, the CMUT may have a contoured electrode.
FILED Tuesday, January 19, 2021
APPL NO 17/152563
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General
B06B 1/0215 (20130101) Original (OR) Class
B06B 1/0651 (20130101)
B06B 1/0662 (20130101)
B06B 2201/55 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174216 Kahn et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Barbara B. Kahn (Cambridge, Massachusetts);  Mark A. Herman (Needham, Massachusetts);  Alan Saghatelian (La Jolla, California);  Edwin Homan (New York, New York);  Mark M. Yore (Boston, Massachusetts);  Ismail Syed (Revere, Massachusetts);  Pedro M. M. Moraes Vieira (Brookline, Massachusetts)
ABSTRACT The invention provides, inter alia, fatty acyl hydroxy fatty acid (FAHFA; a novel class of estolide-related molecules) and diagnostic and treatment methods for a variety of disorders—including diabetes-related disorders, Metabolic Syndrome, polycyctic ovarian syndrome, cancer, and inflammatory disorders—using them; as well as methods of screening for additional compounds that are useful in treating these disorders and/or that modulate FAHFA levels, FAHFA-mediated signaling, and FAHFA-mediated biological effects.
FILED Thursday, March 08, 2018
APPL NO 15/915957
ART UNIT 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 69/22 (20130101) Original (OR) Class
C07C 69/24 (20130101)
C07C 69/58 (20130101)
C07C 69/533 (20130101)

Heterocyclic Compounds
C07D 495/04 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/92 (20130101)
G01N 33/54306 (20130101)
G01N 2500/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174255 Cuny et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas);  TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts)
ASSIGNEE(S) UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas);  TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts)
INVENTOR(S) Gregory Cuny (Houston, Texas);  Sameer Nikhar (Houston, Texas);  Alexei Degterev (Brookline, Massachusetts)
ABSTRACT Identified compounds demonstrate protein kinase inhibitory activity. More specifically, the compounds having the structures below (I) are demonstrated to inhibit receptor interacting kinase 2 (RIPK2) and/or Activin-like kinase 2 (ALK2). Compounds that are either dual RIPK2/ALK2 inhibitors or that preferentially inhibit RIPK2 or ALK2 could provide therapeutic benefit.
FILED Tuesday, May 15, 2018
APPL NO 16/613003
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 471/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174267 Van Vranken et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) David Lee Van Vranken (Irvine, California);  Haoping Liu (Irvine, California);  Ilandari Dewage Udara Anulal Premachandra (Los Angeles, California);  Fuqiang Wang (Irvine, California);  Chengtian Shen (Irvine, California);  Kevin Andre Scott (Vista, California);  Shelley Ren-An Lane (Huntington Beach, California);  Aaron David Mood (Fullerton, California);  Stanley Chungsing Hiew (Irvine, California)
ABSTRACT Small molecules comprised of spiroindolinone analogues are provided. Some spiroindolinones are provided with a particular relative stereochemistry in which the indolone carbonyl and all three hydrogens are on the same face of the central pyrrolidine ring. A stereoselective method of synthesis is provided for making some of the spiroindolinones described above. Formulations and medicaments are also provided that are directed to the treatment of disease, such as, for example, fungal infections. Therapeutics are also provided containing a therapeutically effective dose of one or more small molecule compounds, present either as pharmaceutically effective salt or in pure form, including, but not limited to, formulations for oral, intravenous, or intramuscular administration.
FILED Monday, June 13, 2016
APPL NO 15/735873
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/10 (20180101)

Heterocyclic Compounds
C07D 487/14 (20130101) Original (OR) Class
C07D 487/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174287 Moudgil et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Kamal Moudgil (Silver Spring, Maryland);  Bodhraj Acharya (Baltimore, Maryland)
ASSIGNEE(S) UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland)
INVENTOR(S) Kamal Moudgil (Silver Spring, Maryland);  Bodhraj Acharya (Baltimore, Maryland)
ABSTRACT The present invention provides homing peptides that localize in central nervous system tissue characterized by neuroinflammation and methods of using the same.
FILED Wednesday, January 10, 2018
APPL NO 16/477125
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 47/64 (20170801)
A61K 47/6911 (20170801)
A61K 47/6927 (20170801)
A61K 47/6929 (20170801)
A61K 49/14 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/00 (20180101)
A61P 29/00 (20180101)

Peptides
C07K 7/06 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6896 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174291 Pettit et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) George Robert Pettit (Paradise Valley, Arizona);  Pablo Arce (Tempe, Arizona);  Robin K. Pettit (Fort McDowell, Arizona)
ASSIGNEE(S) Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) George Robert Pettit (Paradise Valley, Arizona);  Pablo Arce (Tempe, Arizona);  Robin K. Pettit (Fort McDowell, Arizona)
ABSTRACT The present disclosure relates to Silstatin compounds, pharmaceutical compositions comprising such compounds, kits, and methods for using such compounds or pharmaceutical compositions.
FILED Thursday, August 08, 2019
APPL NO 16/536039
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/15 (20130101)

Peptides
C07K 11/02 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5011 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174292 Kwong et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Peter Kwong (Washington, District of Columbia);  Barney Graham (Rockville, Maryland);  John Mascola (Rockville, Maryland);  Li Ou (Potomac, Maryland);  Aliaksandr Druz (Germantown, Maryland);  Man Chen (Bethesda, Maryland);  Wing-Pui Kong (Germantown, Maryland);  Ivelin Stefanov Georgiev (Nashville, Tennessee);  Emily Rundlet (New York, New York);  Michael Gordon Joyce (Washington, District of Columbia);  Yaroslav Tsybovsky (Frederick, Maryland);  Paul Thomas (Washington, District of Columbia);  Marie Pancera (Seattle, Washington);  Mallika Sastry (Rockville, Maryland);  Cinque Soto (Nashville, Tennessee);  Joseph Van Galen (North Wales, Pennsylvania);  Guillaume Stewart-Jones (Bethesda, Maryland);  Yongping Yang (Potomac, Maryland);  Baoshan Zhang (Bethesda, Maryland);  Ulrich Baxa (Frederick, Maryland)
ABSTRACT Embodiments of a recombinant Respiratory Syncytial Virus (RSV) F ectodomain trimer stabilized in a prefusion conformation are provided. Also disclosed are nucleic acids encoding the RSV F ectodomain trimer and methods of producing the RSV F ectodomain trimer. Methods for inducing an immune response in a subject are also disclosed. In some embodiments, the method can be a method for treating or preventing a RSV infection in a subject by administering a therapeutically effective amount of the recombinant RSV F ectodomain trimer to the subject.
FILED Wednesday, March 29, 2017
APPL NO 16/089993
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/00 (20130101)
A61K 39/12 (20130101)
A61K 2039/53 (20130101)
A61K 2039/543 (20130101)
A61K 2039/5252 (20130101)
A61K 2039/5254 (20130101)
A61K 2039/55505 (20130101)
A61K 2039/55561 (20130101)
A61K 2039/55566 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)
A61P 37/04 (20180101)

Peptides
C07K 14/005 (20130101) Original (OR) Class
C07K 2319/21 (20130101)
C07K 2319/22 (20130101)
C07K 2319/50 (20130101)
C07K 2319/70 (20130101)
C07K 2319/735 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2710/10343 (20130101)
C12N 2760/18522 (20130101)
C12N 2760/18523 (20130101)
C12N 2760/18534 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174303 Weiss
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S) Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S) Michael A. Weiss (Indianapolis, Indiana)
ABSTRACT A single-chain insulin analogue comprises a B-chain insulin polypeptide connected to an A-chain insulin polypeptide by a C-domain polypeptide. The B-chain insulin polypeptide contains a Cysteine substitution at position B4. The A-chain insulin polypeptide contains a Cysteine substitution at position A10. The C-domain polypeptide is 4 to 11 amino acids long. The analogue mitigates the unfavorable activity of this 4th disulfide bridge in conventional two-chain insulin analogues resulting in a duration of insulin signaling similar to that of wild-type insulin. A method of treating a patient with diabetes mellitus comprises the administration of a physiologically effective amount of the protein or a physiologically acceptable salt thereof to a patient. Use of a single-chain insulin analogue of the present invention in an insulin delivery device (such as a pump or pen) or as part of a high-temperature polymer-melt manufacturing process.
FILED Wednesday, March 07, 2018
APPL NO 16/492824
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 14/62 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174306 Young et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Scripps Research Institute (La Jolla, California)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Travis S. Young (La Jolla, California);  Leonard Presta (La Jolla, California);  David Rodgers (La Jolla, California);  Eric Hampton (La Jolla, California);  Timothy Wright (La Jolla, California);  Peter G. Schultz (La Jolla, California);  Eduardo Laborda (La Jolla, California);  Elvira Khialeeva (La Jolla, California);  Sophie Viaud (La Jolla, California)
ABSTRACT The present disclosure provides compositions, methods, kits, and platforms for selectively activating and deactivating chimeric receptor effector cells using humanized chimeric receptor effector cell switches that comprise a humanized targeting moiety that binds CD19 on a target cell and a chimeric receptor interacting domain that binds to a chimeric receptor effector cell and/or chimeric receptor effector cell switches comprising optimized chimeric receptor interacting domains. Also disclosed are methods of treating disease and conditions with such chimeric receptor effector cells and chimeric receptor effector cell switches.
FILED Thursday, October 19, 2017
APPL NO 16/343353
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/507 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/7051 (20130101)
C07K 14/70517 (20130101)
C07K 14/70521 (20130101)
C07K 14/70578 (20130101)
C07K 16/18 (20130101) Original (OR) Class
C07K 16/2803 (20130101)
C07K 2317/24 (20130101)
C07K 2317/34 (20130101)
C07K 2317/55 (20130101)
C07K 2317/73 (20130101)
C07K 2317/76 (20130101)
C07K 2317/92 (20130101)
C07K 2317/565 (20130101)
C07K 2317/622 (20130101)
C07K 2319/02 (20130101)
C07K 2319/03 (20130101)
C07K 2319/30 (20130101)
C07K 2319/33 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174307 Keane et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) University of Miami (Miami, Florida)
ASSIGNEE(S) UNIVERSITY OF MIAMI (Miami, Florida)
INVENTOR(S) Robert W. Keane (Miami, Florida);  W. Dalton Dietrich (Miami, Florida);  Juan Pablo De Rivero Vaccari (Miami, Florida);  Helen M. Bramlett (Miami, Florida)
ABSTRACT The compositions and methods described herein include methods and agents that inhibit inflammasome signaling in a mammal such as antibodies directed against inflammasome components used alone or in combination with extracellular vesicle uptake inhibitor(s) or other agents. Also described herein are compositions and methods of use thereof for treating viral-associated lung inflammation, for example lung inflammation associated with viral infections such as SARS-CoV-2.
FILED Thursday, April 23, 2020
APPL NO 16/856407
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 16/18 (20130101) Original (OR) Class
C07K 2317/21 (20130101)
C07K 2317/24 (20130101)
C07K 2317/34 (20130101)
C07K 2317/76 (20130101)
C07K 2317/565 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174308 Gavathiotis et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York);  THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (Toronto, Canada)
ASSIGNEE(S) ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (Bronx, New York);  THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (Toronto, Canada)
INVENTOR(S) Evripidis Gavathiotis (Flushing, New York);  Jonathan R. Lai (Dobbs Ferry, New York);  Sachdev Sidhu (Toronto, Canada)
ABSTRACT Synthetic fragment antigen-binding (Fab) antibodies are disclosed that bind to an N-terminal activation site of BCL-2-associated X-protein (BAX) and inhibit BAX activation. Also disclosed are methods of using the Fabs for measuring inactive monomeric BAX levels, screening for small molecules that bind to an N-terminal activation site of BAX, inhibiting apoptotic cell death, and predicting the ability of a cancer therapy to promote apoptotic cell death.
FILED Monday, August 10, 2020
APPL NO 16/988947
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/127 (20130101)
A61K 47/6843 (20170801)

Peptides
C07K 16/005 (20130101)
C07K 16/18 (20130101) Original (OR) Class
C07K 2317/10 (20130101)
C07K 2317/24 (20130101)
C07K 2317/55 (20130101)
C07K 2317/76 (20130101)
C07K 2317/92 (20130101)
C07K 2317/565 (20130101)
C07K 2317/622 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/574 (20130101)
G01N 2500/04 (20130101)
G01N 2510/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174323 Marasco et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S) DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts)
INVENTOR(S) Wayne A. Marasco (Wellsley, Massachusetts);  Agnes Lo (Jamaica Plain, Massachusetts);  Chen Xu (Beijing, China PRC);  Quan Zhu (Southborough, Massachusetts)
ABSTRACT The invention provides scFv antibodies and monoclonal antibodies that bind to and decrease an activity of Carbonic Anhydrase IX (G250). Also provided are the methods of treating and/or preventing cancer, such as renal clear cell cancer. Also provided are methods of identifying a carbonic anhydrase IX (G250) protein. The invention additionally provides methods of modifying immune effector cells, and the immune effector cells modified thereby.
FILED Monday, October 21, 2019
APPL NO 16/658867
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/2013 (20130101)
A61K 39/3955 (20130101)
A61K 51/1045 (20130101)
A61K 51/1075 (20130101)
A61K 2039/505 (20130101)

Peptides
C07K 16/30 (20130101)
C07K 16/40 (20130101) Original (OR) Class
C07K 2317/21 (20130101)
C07K 2317/73 (20130101)
C07K 2317/76 (20130101)
C07K 2317/565 (20130101)
C07K 2317/622 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174325 Fantin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania)
ASSIGNEE(S) CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania)
INVENTOR(S) Marco Fantin (Pittsburgh, Pennsylvania);  Pawel Chmielarz (Pittsburgh, Pennsylvania);  Yi Wang (Pittsburgh, Pennsylvania);  Francesca Lorandi (Pittsburgh, Pennsylvania);  Krzysztof Matyjaszewski (Pittsburgh, Pennsylvania)
ABSTRACT Systems and methods for Atom Transfer Radical Polymerization (ATRP) emulsion polymerization are provided. The ATRP emulsion polymerization comprises a suspending medium, a dispersed medium, a surfactant, a transition metal compound in a higher oxidation state, a ligand, and an ATRP initiator. The transition metal compound is capable of forming a catalyst complex in a presence of the ligand. The catalyst complex is soluble in the suspending medium and is capable of forming an ionic complex with the surfactant. The ionic complex is capable of moving between the suspending medium and the dispersed medium. A portion of the transition metal compound in the higher oxidation state within a portion of the catalyst complex is reduced by a physical and/or a chemical procedure thereby initiating a polymerization of one or more radically (co)polymerizable monomers by reaction with the initiator.
FILED Thursday, January 11, 2018
APPL NO 16/475886
ART UNIT 1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 2/26 (20130101)
C08F 2/38 (20130101) Original (OR) Class
C08F 4/10 (20130101)
C08F 4/40 (20130101)
C08F 220/18 (20130101)
C08F 2438/01 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174326 Scott et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Timothy F. Scott (Ann Arbor, Michigan);  Harry van der Laan (Ann Arbor, Michigan);  Megan A. Cole (Ann Arbor, Michigan);  Mark A. Burns (Ann Arbor, Michigan);  Martin P. De Beer (Ann Arbor, Michigan);  Zachary D. Pritchard (Ann Arbor, Michigan);  Avi Bregman (Ann Arbor, Michigan)
ABSTRACT Provided herein is technology relating to polymerization and producing polymers and particularly, but not exclusively, to methods, systems, and compositions for producing articles using three-dimensional printing and for improving control of polymerization using a polymerization photoinhibitor having fast back reaction kinetics such as hexaarylbiimidazole compounds and bridged hexaarylbiimidazole compounds.
FILED Tuesday, February 19, 2019
APPL NO 16/970600
ART UNIT 1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 2/50 (20130101) Original (OR) Class
C08F 4/04 (20130101)
C08F 4/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174486 Hasty et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Environmental Health Sciences (NIEHS)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Regents of the University of California (Oakland, California);  Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Jeff Hasty (Encinitas, California);  Lev Tsimring (San Diego, California);  Muhammad Omar Din (San Diego, California);  Arthur Prindle (San Diego, California);  Sangeeta Bhatia (Lexington, Massachusetts);  Tal Danino (Cambridge, Massachusetts)
ABSTRACT Some embodiments described herein relate to cells which have been genetically engineered to release a polypeptide when a population of the cells reaches a desired density. In some embodiments, the released polypeptide may be a therapeutic polypeptide. In some embodiments, the therapeutic polypeptide kills tumor cells or which inhibits the growth of tumor cells.
FILED Thursday, April 07, 2016
APPL NO 15/565131
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/74 (20130101)
A61K 38/16 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/06 (20130101)
C12N 1/20 (20130101)
C12N 15/63 (20130101)
C12N 15/74 (20130101) Original (OR) Class

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 21/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174495 Zemelman
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Boris Zemelman (Austin, Texas)
ABSTRACT The present invention provides methods and compositions for labeling and/or targeting cells with increased calcium by providing a CREB reporter system. In addition, methods of treating disorders with activated cells such as brain disorders or cancer are also provided herein.
FILED Monday, December 05, 2016
APPL NO 15/780852
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 48/0066 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/63 (20130101)
C12N 15/85 (20130101)
C12N 15/86 (20130101) Original (OR) Class
C12N 15/113 (20130101)
C12N 2830/001 (20130101)
C12N 2830/005 (20130101)
C12N 2830/008 (20130101)
C12N 2830/30 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6897 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174515 Abudayyeh et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts);  MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts);  PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Omar Abudayyeh (Cambridge, Massachusetts);  James Joseph Collins (Newton, Massachusetts);  Jonathan Gootenberg (Cambridge, Massachusetts);  Feng Zhang (Cambridge, Massachusetts);  Eric S. Lander (Cambridge, Massachusetts);  Aviv Regev (Cambridge, Massachusetts)
ABSTRACT The embodiments disclosed herein utilized RNA targeting effectors to provide a robust CRISPR-based diagnostic with attomolar sensitivity. Embodiments disclosed herein can detect both DNA and RNA with comparable levels of sensitivity and can differentiate targets from non-targets based on single base pair differences. Moreover, the embodiments disclosed herein can be prepared in freeze-dried format for convenient distribution and point-of-care (POC) applications. Such embodiments are useful in multiple scenarios in human health including, for example, viral detection, bacterial strain typing, sensitive genotyping, and detection of disease-associated cell free DNA.
FILED Thursday, March 15, 2018
APPL NO 15/922576
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/11 (20130101)
C12N 2310/20 (20170501)
C12N 2800/80 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/689 (20130101)
C12Q 1/6804 (20130101)
C12Q 1/6804 (20130101)
C12Q 1/6827 (20130101)
C12Q 1/6827 (20130101)
C12Q 1/6827 (20130101)
C12Q 1/6827 (20130101)
C12Q 1/6883 (20130101) Original (OR) Class
C12Q 1/6886 (20130101)
C12Q 1/6888 (20130101)
C12Q 2521/301 (20130101)
C12Q 2521/301 (20130101)
C12Q 2521/301 (20130101)
C12Q 2521/301 (20130101)
C12Q 2521/337 (20130101)
C12Q 2525/205 (20130101)
C12Q 2525/205 (20130101)
C12Q 2565/1015 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174518 You et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Cedars-Sinai Medical Center (Los Angeles, California)
ASSIGNEE(S) Cedars-Sinai Medical Center (Los Angeles, California)
INVENTOR(S) Sungyong You (Los Angeles, California);  Michael Freeman (West Hollywood, California);  Jayoung Kim (Beverly Hills, California);  Beatrice Knudsen (Los Angeles, California)
ABSTRACT The invention provides various methods for classifying prostate cancers into subtypes. The classification methods may be used to diagnose or prognose prostate cancers. In one embodiment, the subtypes are PCS1, PCS2, or PCS3. In one embodiment, the PCS1 subtype is most likely to progress to metastatic disease or prostate cancer specific mortality when compared to the PCS2 subtype or PCS3 subtype. In one embodiment, the PCS1 subtype is resistant to enzalutamide.
FILED Wednesday, October 05, 2016
APPL NO 15/764185
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/337 (20130101)
A61K 31/506 (20130101)
A61K 31/4166 (20130101)
A61K 33/243 (20190101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/112 (20130101)
C12Q 2600/158 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 20/00 (20190201)
G16B 20/20 (20190201)
G16B 25/00 (20190201)
G16B 25/10 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174952 Harbrecht et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Semba Biosciences, Inc. (Madison, Wisconsin)
ASSIGNEE(S) Semba Biosciences, Inc. (Madison, Wisconsin)
INVENTOR(S) Brian A. Harbrecht (Janesville, Wisconsin);  Robert Charles Mierendorf (Verona, Wisconsin);  Scott G. Manke (Sun Prairie, Wisconsin)
ABSTRACT An illustrative valve block includes a plate, a fluid transfer block, and a diaphragm. The plate includes a channel configured to receive a first fluid and a recess connected to the channel. The fluid transfer block includes an inlet connection configured to receive a second fluid and an outlet connection. The fluid transfer block also includes a plurality of valve inlet bores connected to the inlet connection. The plurality of valve inlet bores are distributed along at least part of a first curved shape. The fluid transfer block further includes a plurality of valve outlet bores each fluidly connected to the outlet connection. The plurality of valve outlet bores are distributed along at least part of a second curved shape. The diaphragm is between the pressure plate and the fluid transfer block. The plurality of valve inlet bores and the plurality of valve outlet bores adjoin the recess.
FILED Friday, October 18, 2019
APPL NO 16/657670
ART UNIT 3753 — Fluid Handling and Dispensing
CURRENT CPC
Separation
B01D 15/22 (20130101)
B01D 15/1842 (20130101)

Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating
F16K 7/17 (20130101) Original (OR) Class
F16K 11/22 (20130101)
F16K 25/005 (20130101)
F16K 27/003 (20130101)
F16K 27/0236 (20130101)
F16K 27/0263 (20130101)
F16K 31/1266 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11175280 Di Carlo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, Georgia)
INVENTOR(S) Dino Di Carlo (Los Angeles, California);  Peter Tseng (Saratoga, California);  Ivan Pushkarsky (San Diego, California)
ABSTRACT A system for assaying forces applied by cells includes an optically transparent substrate comprising a soft material having a Young's modulus within the range of about 3 kPa to about 100 kPa. An array of molecular patterns is disposed on a surface of the optically transparent substrate, the molecular patterns include fluorophore-conjugated patterns adherent to cells. The system includes at least one light source configured to excite the fluorophore-conjugated patterns and an imaging device configured to capture fluorescent light emitted from the fluorophore-conjugated patterns. Dimensional changes in the size of the patterns are used to determine contractile forces imparted by cells located on the patterns.
FILED Friday, September 25, 2020
APPL NO 17/033488
ART UNIT 2886 — Optics
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5085 (20130101)
B01L 2300/168 (20130101)
B01L 2300/0654 (20130101)
B01L 2300/0829 (20130101)

Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 1/247 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6458 (20130101)
G01N 33/487 (20130101)
G01N 33/582 (20130101)
G01N 33/5026 (20130101) Original (OR) Class
G01N 2021/6419 (20130101)
G01N 2021/6441 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11176677 Fuchs et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York)
ASSIGNEE(S) MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York)
INVENTOR(S) Thomas Fuchs (New York, New York);  David Joon Ho (New York, New York)
ABSTRACT Described herein are systems and methods of training models to segment images. A device may identify a training dataset. The training dataset may include images each having a region of interest. The training dataset may include first annotations. The device may train, using the training dataset, an image segmentation model having parameters to generate a corresponding first segmented images. The device may provide the first segmented images for presentation on a user interface to obtain feedback. The device may receive, via the user interface, a feedback dataset including second annotations for at least a subset of the first segmented images. Each of the second annotations may label at least a second portion of the region of interest in a corresponding image of the subset. The device may retrain, using the feedback dataset received via the user interface, the image segmentation model.
FILED Monday, March 15, 2021
APPL NO 17/201826
ART UNIT 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/6202 (20130101)
G06K 9/6267 (20130101)

Image Data Processing or Generation, in General
G06T 7/11 (20170101)
G06T 7/187 (20170101) Original (OR) Class
G06T 2207/20081 (20130101)
G06T 2207/30024 (20130101)
G06T 2207/30096 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11176717 Majeed et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Siemens Healthcare GmbH (Erlangen, Germany);  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland)
ASSIGNEE(S) Siemens Healthcare GmbH (Erlangen, Germany);  The United States of America, as Represented by the Secretary. Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Waqas Majeed (Ellicott City, Maryland);  Sunil Goraksha Patil (Ellicott City, Maryland);  Rainer Schneider (Erlangen, Germany);  Himanshu Bhat (Newton, Massachusetts);  Adrienne Campbell (Bethesda, Maryland)
ABSTRACT A method for decomposing noise into white and spatially correlated components during MR thermometry imaging includes acquiring a series of MR images of an anatomical object and generating a series of temperature difference maps of the anatomical object. The method further includes receiving a selection of a region of interest (ROI) within the temperature difference map and estimating total noise variance values depicting total noise variance in the temperature difference map. Each total noise variance value is determined using a random sampling of a pre-determined number of voxels from the ROI. A white noise component and a spatially correlated noise component of the total noise variance providing a best fit to the total noise variance values for all of the random samplings are identified. The white noise component and the spatially correlated noise component are displayed on a user interface.
FILED Thursday, September 26, 2019
APPL NO 16/583596
ART UNIT 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Electric Digital Data Processing
G06F 3/0482 (20130101)

Image Data Processing or Generation, in General
G06T 5/002 (20130101)
G06T 5/50 (20130101)
G06T 7/0016 (20130101)
G06T 11/008 (20130101) Original (OR) Class
G06T 11/203 (20130101)
G06T 2207/10088 (20130101)
G06T 2207/20182 (20130101)
G06T 2207/30016 (20130101)
G06T 2207/30056 (20130101)
G06T 2207/30096 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11177020 Jabara et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S) Cassandra B. Jabara (Ridgefield, Connecticut);  Jeffrey A. Anderson (Pennington, New Jersey);  Ronald I. Swanstrom (Chapel Hill, North Carolina)
ABSTRACT Methods and uses for molecular tags are disclosed. Molecular tags may be attached to nucleic acid molecules. The attachment of the nucleic acid molecules prior to PCR amplification and sequencing improves the accuracy of genetic analysis and detection of genetic variations and diversity. Molecular tags may also be used for detection of drug-resistant variants. Methods for using molecular tags for determining and correcting PCR errors and/or sequencing error are also disclosed.
FILED Wednesday, February 27, 2013
APPL NO 14/381526
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/689 (20130101)
C12Q 1/689 (20130101)
C12Q 1/703 (20130101)
C12Q 1/6853 (20130101)
C12Q 1/6853 (20130101)
C12Q 1/6874 (20130101)
C12Q 2525/161 (20130101)
C12Q 2525/161 (20130101)
C12Q 2537/159 (20130101)
C12Q 2537/159 (20130101)
C12Q 2600/16 (20130101)
C12Q 2600/156 (20130101)
C12Q 2600/172 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 30/00 (20190201)
G16B 30/10 (20190201) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 11173056 Altobelli et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army
Research, Development and Engineering Command (RDECOM)
APPLICANT(S) DEKA Products Limited Partnership (Manchester, New Hampshire)
ASSIGNEE(S) DEKA PRODUCTS LIMITED PARTNERSHIP (Manchester, New Hampshire)
INVENTOR(S) David E. Altobelli (Hollis, New Hampshire);  N. Christopher Perry (Manchester, New Hampshire)
ABSTRACT A dynamic support apparatus having a frame, a dynamic interface, a temperature control mechanism, and a control system. The dynamic interface is capable of changing its geometry and is disposed on the top surface of the frame. The control system is operably connected to the dynamic interface and controls the changing geometry of the dynamic interface. There is also a temperature control mechanism disposed on the top surface of the frame for maintaining a comfortable temperature and moisture environment between the apparatus and the user's body.
FILED Monday, October 27, 2014
APPL NO 14/524790
ART UNIT 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/70 (20130101)
A61F 2/602 (20130101)
A61F 2/7843 (20130101) Original (OR) Class
A61F 5/012 (20130101)
A61F 2002/501 (20130101)
A61F 2002/5012 (20130101)
A61F 2002/5032 (20130101)
A61F 2002/7615 (20130101)
A61F 2002/7887 (20130101)
A61F 2007/006 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 33/3842 (20130101)

Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles
B29L 2031/753 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173093 Mooney et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Dephy, Inc. (Maynard, Massachusetts)
ASSIGNEE(S) Dephy, Inc. (Maynard, Massachusetts)
INVENTOR(S) Luke Mooney (Sudbury, Massachusetts);  Jean-François Duval (Belmont, Massachusetts);  Nicholas Benz (Belmont, Massachusetts);  Jonathan Cummings (Concord, Massachusetts);  Matthew Mooney (Westford, Massachusetts)
ABSTRACT An apparatus for a battery-powered active exoskeleton boot includes a shin pad and one or more housings. The one or more housings enclose electronic circuitry and an electric motor. The apparatus includes a battery holder coupled to the shin pad and located below the knee of the user and above the one or more housings enclosing the electronic circuitry. The apparatus includes a battery module removably affixed to the battery holder and comprising a first power connector that electrically couples to a second power connector located in the battery holder while attached to the battery holder to provide electric power to the electronic circuitry and the electric motor. The apparatus includes an output shaft coupled to the electric motor. The electronic circuitry controls delivery of power from the battery module to the electric motor to generate torque about the axis of rotation of the ankle joint of the user.
FILED Wednesday, September 16, 2020
APPL NO 17/022982
ART UNIT 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 5/00 (20130101)

Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body
A61H 3/00 (20130101) Original (OR) Class

Manipulators; Chambers Provided With Manipulation Devices
B25J 9/0006 (20130101)
B25J 9/0009 (20130101)
B25J 9/16 (20130101)
B25J 19/005 (20130101)

Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils
H02P 1/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173154 Marazzi
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Research Office (ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Centers of Excellence for Influenza Research and Response (CEIRR)
Center for Research on Influenza Pathogenesis (CRIP)
APPLICANT(S) ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York)
ASSIGNEE(S) ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York)
INVENTOR(S) Ivan Marazzi (New York, New York)
ABSTRACT A method of treating a disease, condition or state characterized by an exacerbated immune response is disclosed. The method of treatment can include topoisomerase I inhibitors and pharmaceutical compositions comprising topoisomerase I inhibitors, which can be administered alone or in combination with another therapeutic agent. The method can be used to treat a range of diseases, disorders, conditions and states, including but not limited to sepsis, acute liver failure, and endotoxic and/or exotoxic shock. These diseases, disorders, conditions and states can be caused by a variety of microorganisms and/or portions of microorganisms including but not limited to Ebola virus, Lassa virus, Influenza virus, Legionella, lipopolysaccharide (LPS), and bacterial endotoxins/exotoxins.
FILED Thursday, December 15, 2016
APPL NO 16/063009
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/05 (20130101)
A61K 31/473 (20130101)
A61K 31/4745 (20130101) Original (OR) Class
A61K 38/005 (20130101)
A61K 45/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173175 Lee
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
INVENTOR(S) Byeong-Chel Lee (Pittsburgh, Pennsylvania)
ABSTRACT The present invention provides for compositions and methods for administering one or more UDP compound, alone or in combination with another hematopoietic progenitor cell mobilizing compound (for example, but not limited to G-CSF), to mobilize hematopoietic progenitor cells for transplant or other purposes. The methods of the invention may be particularly advantageous as applied to improve the stem cell yield in so-called “poor mobilizing” patients.
FILED Wednesday, August 17, 2016
APPL NO 15/239614
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/395 (20130101)
A61K 31/664 (20130101)
A61K 31/737 (20130101)
A61K 31/7072 (20130101) Original (OR) Class
A61K 31/7072 (20130101)
A61K 35/00 (20130101)
A61K 35/12 (20130101)
A61K 35/28 (20130101)
A61K 38/193 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173464 Roper et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Christopher S. Roper (Oak Park, California);  Shanying Cui (Calabasas, California);  Adam F. Gross (Santa Monica, California)
ABSTRACT Some variations provide a method of assembling a plurality of particles into particle assemblies, comprising: (a) obtaining a first fluid containing particles and a solvent for the particles; (b) obtaining a second fluid not fully miscible with the first fluid; (c) obtaining a third fluid that is a co-solvent for the first fluid and the second fluid; (d) combining the first fluid and the second fluid to generate an emulsion containing droplets of the first fluid in the second fluid; (e) adding the third fluid to the emulsion; and (f) dissolving out the solvent from the droplets into the third fluid, thereby forming particle assemblies. Some variations also provide an assembly of nanoparticles, wherein the assembly has a volume from 1 μm3 to 1 mm3, a packing fraction from 20% to 100%, and/or an average relative surface roughness less than 1%, wherein the assembly is not disposed on a substrate.
FILED Monday, May 13, 2019
APPL NO 16/411061
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 13/10 (20130101) Original (OR) Class

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173490 Moore et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) GENERAL ELECTRIC COMPANY (Schenectady, New York);  University of Washington (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington);  Global Life Sciences Solutions Operations UK Ltd. (Sheffield, United Kingdom)
INVENTOR(S) David Roger Moore (Schenectady, New York);  Matthew Jeremiah Misner (Delanson, New York);  Andrew Arthur Paul Burns (Schenectady, New York);  Joshua Bishop (Seattle, Washington);  Lisa K. Lafleur (Seattle, Washington);  Maxwell Wheeler (Seattle, Washington)
ABSTRACT The present disclosure relates to a sample assessment device. By way of example, the sample assessment device may include a substrate including a sample application region; an amplification region comprising a plurality of amplification reagents; a waste region comprising an entrance fluidically coupled to the amplification region and extending away from the amplification region; and a detection region spaced apart from the amplification region. The sample assessment device may also include a valve coupled to the substrate and configured to separate the amplification region from the detection region in a closed configuration, wherein the amplification region and the valve are positioned on the sample assessment device between the sample application region and the detection region and wherein the sample assessment device is configured to permit lateral flow from the amplification region to the detection region when the valve is in an open configuration.
FILED Monday, July 16, 2018
APPL NO 16/036430
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5023 (20130101)
B01L 3/502738 (20130101)
B01L 7/52 (20130101) Original (OR) Class
B01L 2200/10 (20130101)
B01L 2200/027 (20130101)
B01L 2300/18 (20130101)
B01L 2300/126 (20130101)
B01L 2300/0627 (20130101)
B01L 2300/0816 (20130101)
B01L 2300/0864 (20130101)
B01L 2300/0874 (20130101)
B01L 2300/0887 (20130101)
B01L 2400/06 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101)
C12Q 1/6806 (20130101)
C12Q 1/6844 (20130101)
C12Q 1/6844 (20130101)
C12Q 2565/629 (20130101)
C12Q 2565/629 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173617 Farritor et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Board of Regents of the University of Nebraska (Lincoln, Nebraska)
ASSIGNEE(S) BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska)
INVENTOR(S) Shane Farritor (Lincoln, Nebraska);  Thomas Frederick (Lincoln, Nebraska)
ABSTRACT The various embodiments herein relate to a coupling apparatus for a medical device having a coupler body, a cavity defined in the coupler body, a rotatable drive component disposed within the cavity and having at least two pin-receiving openings, and an actuable locking ring disposed around the cavity.
FILED Friday, August 25, 2017
APPL NO 15/687113
ART UNIT 3678 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/00234 (20130101)
A61B 34/30 (20160201)
A61B 34/70 (20160201)
A61B 2017/00477 (20130101)
A61B 2017/2931 (20130101)

Manipulators; Chambers Provided With Manipulation Devices
B25J 15/0408 (20130101)
B25J 19/0029 (20130101) Original (OR) Class

Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors
H01R 13/005 (20130101)
H01R 13/24 (20130101)
H01R 13/625 (20130101)
H01R 24/20 (20130101)
H01R 24/86 (20130101)
H01R 2107/00 (20130101)
H01R 2201/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174013 Olson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
Redstone Arsenal (REDSTONE)
APPLICANT(S) Textron Innovations Inc. (Providence, Rhode Island)
ASSIGNEE(S) Textron Innovations Inc. (Providence, Rhode Island)
INVENTOR(S) Eric Stephen Olson (Fort Worth, Texas);  David Andrew Prater (Hurst, Texas)
ABSTRACT A failsafe multimode clutch assembly is positioned in a powertrain of a rotorcraft. The clutch assembly includes a freewheeling unit having input and output races. The freewheeling unit has a driving mode in which torque applied to the input race is transferred to the output race and an overrunning mode in which torque applied to the output race is not transferred to the input race. A bypass assembly has an engaged position that couples the input and output races of the freewheeling unit. An actuator assembly must be energized to shift the bypass assembly from the engaged position to a disengaged position. In the disengaged position, the overrunning mode of the freewheeling unit is enabled such that the clutch assembly is configured for unidirectional torque transfer. In the engaged position, the overrunning mode of the freewheeling unit is disabled such that the clutch assembly is configured for bidirectional torque transfer.
FILED Tuesday, September 29, 2020
APPL NO 17/037476
ART UNIT 3659 — Material and Article Handling
CURRENT CPC
Aeroplanes; Helicopters
B64C 27/06 (20130101)
B64C 27/12 (20130101) Original (OR) Class

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 27/10 (20130101)
B64D 27/24 (20130101)
B64D 35/02 (20130101)

Couplings for Transmitting Rotation; Clutches; Brakes
F16D 25/14 (20130101)
F16D 25/061 (20130101)
F16D 28/00 (20130101)
F16D 41/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174014 Olson
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
Redstone Arsenal (REDSTONE)
APPLICANT(S) Textron Innovations Inc. (Providence, Rhode Island)
ASSIGNEE(S) Textron Innovations Inc. (Providence, Rhode Island)
INVENTOR(S) Eric Stephen Olson (Fort Worth, Texas)
ABSTRACT A failsafe multimode clutch assembly is positioned in a powertrain of a rotorcraft. The clutch assembly includes a freewheeling unit having input and output races. The freewheeling unit has a driving mode in which torque applied to the input race is transferred to the output race and an overrunning mode in which torque applied to the output race is not transferred to the input race. A bypass assembly has an engaged position that couples the input and output races of the freewheeling unit. An actuator assembly must be energized to shift the bypass assembly from the engaged position to a disengaged position. In the disengaged position, the overrunning mode of the freewheeling unit is enabled such that the clutch assembly is configured for unidirectional torque transfer. In the engaged position, the overrunning mode of the freewheeling unit is disabled such that the clutch assembly is configured for bidirectional torque transfer.
FILED Tuesday, September 29, 2020
APPL NO 17/037512
ART UNIT 3659 — Material and Article Handling
CURRENT CPC
Aeroplanes; Helicopters
B64C 27/06 (20130101)
B64C 27/12 (20130101) Original (OR) Class

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 27/10 (20130101)
B64D 27/24 (20130101)
B64D 35/02 (20130101)

Couplings for Transmitting Rotation; Clutches; Brakes
F16D 25/14 (20130101)
F16D 25/061 (20130101)
F16D 28/00 (20130101)
F16D 41/06 (20130101)
F16D 41/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174015 Goodwin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
Redstone Arsenal (REDSTONE)
APPLICANT(S) Textron Innovations Inc. (Providence, Rhode Island)
ASSIGNEE(S) Textron Innovations Inc. (Providence, Rhode Island)
INVENTOR(S) Douglas Andrew Goodwin (Fort Worth, Texas);  David Andrew Prater (Hurst, Texas);  Eric Stephen Olson (Fort Worth, Texas);  David Bryan Roberts (Bedford, Texas);  Chia-Wei Su (Lewisville, Texas);  Michael David Trantham (Arlington, Texas);  Charles Eric Covington (Colleyville, Texas)
ABSTRACT A multimode clutch assembly is positioned in a powertrain of a rotorcraft. The clutch assembly includes a freewheeling unit having a driving mode in which torque applied to the input race is transferred to the output race and an overrunning mode in which torque applied to the output race is not transferred to the input race. A bypass assembly has an engaged position that couples the input and output races of the freewheeling unit. An actuator assembly shifts the bypass assembly between engaged and disengaged positions. An engagement status sensor is configured to determine the engagement status of the bypass assembly. In the disengaged position, the overrunning mode of the freewheeling unit is enabled such that the clutch assembly is configured for unidirectional torque transfer. In the engaged position, the overrunning mode of the freewheeling unit is disabled such that the clutch assembly is configured for bidirectional torque transfer.
FILED Monday, October 05, 2020
APPL NO 17/063712
ART UNIT 3659 — Material and Article Handling
CURRENT CPC
Aeroplanes; Helicopters
B64C 27/12 (20130101) Original (OR) Class

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 35/08 (20130101)
B64D 2027/026 (20130101)

Couplings for Transmitting Rotation; Clutches; Brakes
F16D 41/04 (20130101)
F16D 2041/0603 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174352 Hill et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Research Office (ARO)
APPLICANT(S) Emory University (Atlanta, Georgia)
ASSIGNEE(S) Emory University (Atlanta, Georgia)
INVENTOR(S) Craig Hill (Atlanta, Georgia);  Kevin Sullivan (Atlanta, Georgia)
ABSTRACT This disclosure relates to polymers and polymer compositions having monomer units of polyoxometalates and monomer units comprising hydroxy-terminated molecules such as branched molecules or dendrimers and uses in degradation, decontamination, and deodorization. In certain embodiments, the hydroxy-terminated branched molecules or dendrimers comprise terminal 1,1-tris(hydroxymethyl)methyl or 1,1,1-tris(hydroxyalkyl)methyl groups. In certain embodiments, the hydroxy-terminated molecule is N,N′,N″-tris[tris(hydroxymethyl) methyl]-1,3,5-benzenetricarboxamide.
FILED Friday, December 09, 2016
APPL NO 16/061327
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus
A62D 3/35 (20130101)
A62D 3/38 (20130101)
A62D 2101/02 (20130101)
A62D 2101/26 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 83/001 (20130101)
C08G 83/003 (20130101) Original (OR) Class
C08G 83/004 (20130101)
C08G 2261/37 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174353 Old et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army
Army Research Office (ARO)
Subcellular Pan-Omics for Advanced Rapid Threat Assessment (SPARTA)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado)
ASSIGNEE(S) The Regents of the University of Colorado (Denver, Colorado)
INVENTOR(S) William Old (Denver, Colorado);  Douglas A. Chapnick (Boulder, Colorado);  Tristan D. McClure-Begley (Lafayette, Colorado);  Tao Gong (Superior, Colorado);  Brady Worrell (Boulder, Colorado);  Christopher C. Ebmeier (Arvada, Colorado);  Christopher Bowman (Boulder, Colorado)
ABSTRACT Crosslinking compounds for effective and efficient cross-linking and identification of intermolecular and intramolecular interactions of proteins, peptides and nucleic acids.
FILED Tuesday, March 05, 2019
APPL NO 16/293191
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Derivatives of Natural Macromolecular Compounds
C08H 1/00 (20130101) Original (OR) Class

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 5/10 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6848 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174359 Gunckel et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Research Office (ARO)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S) Ryan Gunckel (Tempe, Arizona);  Lenore Dai (Phoenix, Arizona);  Aditi Chattopadhyay (Chandler, Arizona);  Bonsung Koo (Tempe, Arizona)
ABSTRACT Composite material can include a matrix material, a fiber dispersed in the matrix material, and an ultraviolet (UV)-light sensitive mechanophore grafted to a surface of the fiber. A method for making a fiber-reinforced polymer composite can include contacting a fiber in a first solution, rinsing and then drying intermediate fiber, contacting dried fiber in a third solution, rinsing, and then drying the rinsed fiber thereby generating functionalized fiber that is sensitive to ultraviolet light. The functionalized fiber can be combined with a polymer matrix material, cured, and irradiated, thereby generating a fiber-reinforced polymer composite.
FILED Monday, April 22, 2019
APPL NO 16/390969
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 3/28 (20130101)
C08J 5/08 (20130101) Original (OR) Class
C08J 5/042 (20130101)
C08J 2363/00 (20130101)

Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 1/429 (20130101)

Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 1/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174418 Chipara et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) William Marsh Rice University (Houston, Texas);  The Board of Regents of The University Of Texas System (Austin, Texas)
ASSIGNEE(S) William Marsh Rice University (Houston, Texas);  Board of Regents of the University of Texas System (Austin, Texas)
INVENTOR(S) Alin C. Chipara (McAllen, Texas);  Mircea Chipara (McAllen, Texas);  Chandra S. Tiwary (Houston, Texas);  Pulickel M. Ajayan (Houston, Texas)
ABSTRACT Embodiments of the present disclosure pertain to adhesive compositions that include a fluorinated molecule and a hydrogen-containing molecule that are non-covalently associated with one another. The molecules may be non-covalently associated with one another through dipole-dipole interactions that create a fluorine-hydrogen electronegativity difference between at least some of the fluorine atoms of the fluorinated molecule and at least some of the hydrogen atoms of the hydrogen-containing molecule. The fluorinated molecule and the hydrogen-containing molecule may be in different phases, such as a liquid phase for one molecule and a solid phase for the other molecule. Additional embodiments pertain to methods of enhancing an adhesiveness of a surface by applying an adhesive composition of the present disclosure to the surface. Further embodiments pertain to methods of making the adhesive compositions by mixing a fluorinated molecule with a hydrogen-containing molecule such that the molecules become non-covalently associated with one another.
FILED Tuesday, June 27, 2017
APPL NO 16/312801
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Compositions of Macromolecular Compounds
C08L 27/16 (20130101)
C08L 83/04 (20130101)
C08L 101/02 (20130101)

Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives
C09J 11/00 (20130101)
C09J 127/16 (20130101)
C09J 127/18 (20130101) Original (OR) Class
C09J 183/04 (20130101)
C09J 183/04 (20130101)
C09J 201/04 (20130101)
C09J 201/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174460 Gurtner et al.
FUNDED BY
Department of Defense (DOD)
Armed Forces Institute of Regenerative Medicine (AFIRM)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Geoffrey C. Gurtner (Palo Alto, California);  Jayakumar Rajadas (Cupertino, California);  Robert C. Rennert (Palo Alto, California)
ASSIGNEE(S)
INVENTOR(S) Geoffrey C. Gurtner (Palo Alto, California);  Jayakumar Rajadas (Cupertino, California);  Robert C. Rennert (Palo Alto, California);  Dominik Duscher (Linz, Austria)
ABSTRACT Efficient stem cell delivery into biomaterials using capillary driven encapsulation are disclosed herein where stem/progenitor and/or tissue specific cells are rapidly and efficiently seeded via capillary driven encapsulation into a porous scaffold for cell delivery in the skin or any other organ. The rapid capillary force approach maximizes both seeding time and efficiency by combining hydrophobic, entropic and capillary forces to promote active, ‘bottom-up’ cell engraftment. This methodology uses micro domain patterned biopolymers in a porous dry gel to generate capillary pressure to move a viscous stem cell mix from a hydrophobic reservoir into the polymer matrix to promote active cell seeding within the entire gel volume.
FILED Thursday, December 17, 2015
APPL NO 14/973283
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/12 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 17/02 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0068 (20130101) Original (OR) Class
C12N 2527/00 (20130101)
C12N 2533/30 (20130101)
C12N 2533/54 (20130101)
C12N 2533/70 (20130101)
C12N 2535/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174477 Ismagilov et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Rustem Ismagilov (Altadena, California);  Erik Jue (Pasadena, California);  Daan Witters (San Diego, California)
ABSTRACT Methods and systems and related compositions for separating through a solid matrix a mixture comprising a nucleic acid together with a target compound having a water solubility equal to or greater than 0.01 mg per 100 mL, which can be used for managing fluid flow, biochemical reactions and purification of the nucleic acid or other target analytes.
FILED Friday, September 14, 2018
APPL NO 16/132235
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/508 (20130101)
B01L 3/50851 (20130101)
B01L 3/502753 (20130101)
B01L 7/52 (20130101)
B01L 2200/0631 (20130101)
B01L 2200/0689 (20130101)
B01L 2300/04 (20130101)
B01L 2300/18 (20130101)
B01L 2300/069 (20130101)
B01L 2300/0672 (20130101)
B01L 2400/0605 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1003 (20130101) Original (OR) Class
C12N 15/1006 (20130101)
C12N 15/1013 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6428 (20130101)
G01N 21/6456 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174515 Abudayyeh et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts);  MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts);  PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Omar Abudayyeh (Cambridge, Massachusetts);  James Joseph Collins (Newton, Massachusetts);  Jonathan Gootenberg (Cambridge, Massachusetts);  Feng Zhang (Cambridge, Massachusetts);  Eric S. Lander (Cambridge, Massachusetts);  Aviv Regev (Cambridge, Massachusetts)
ABSTRACT The embodiments disclosed herein utilized RNA targeting effectors to provide a robust CRISPR-based diagnostic with attomolar sensitivity. Embodiments disclosed herein can detect both DNA and RNA with comparable levels of sensitivity and can differentiate targets from non-targets based on single base pair differences. Moreover, the embodiments disclosed herein can be prepared in freeze-dried format for convenient distribution and point-of-care (POC) applications. Such embodiments are useful in multiple scenarios in human health including, for example, viral detection, bacterial strain typing, sensitive genotyping, and detection of disease-associated cell free DNA.
FILED Thursday, March 15, 2018
APPL NO 15/922576
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/11 (20130101)
C12N 2310/20 (20170501)
C12N 2800/80 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/689 (20130101)
C12Q 1/6804 (20130101)
C12Q 1/6804 (20130101)
C12Q 1/6827 (20130101)
C12Q 1/6827 (20130101)
C12Q 1/6827 (20130101)
C12Q 1/6827 (20130101)
C12Q 1/6883 (20130101) Original (OR) Class
C12Q 1/6886 (20130101)
C12Q 1/6888 (20130101)
C12Q 2521/301 (20130101)
C12Q 2521/301 (20130101)
C12Q 2521/301 (20130101)
C12Q 2521/301 (20130101)
C12Q 2521/337 (20130101)
C12Q 2525/205 (20130101)
C12Q 2525/205 (20130101)
C12Q 2565/1015 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174518 You et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Cedars-Sinai Medical Center (Los Angeles, California)
ASSIGNEE(S) Cedars-Sinai Medical Center (Los Angeles, California)
INVENTOR(S) Sungyong You (Los Angeles, California);  Michael Freeman (West Hollywood, California);  Jayoung Kim (Beverly Hills, California);  Beatrice Knudsen (Los Angeles, California)
ABSTRACT The invention provides various methods for classifying prostate cancers into subtypes. The classification methods may be used to diagnose or prognose prostate cancers. In one embodiment, the subtypes are PCS1, PCS2, or PCS3. In one embodiment, the PCS1 subtype is most likely to progress to metastatic disease or prostate cancer specific mortality when compared to the PCS2 subtype or PCS3 subtype. In one embodiment, the PCS1 subtype is resistant to enzalutamide.
FILED Wednesday, October 05, 2016
APPL NO 15/764185
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/337 (20130101)
A61K 31/506 (20130101)
A61K 31/4166 (20130101)
A61K 33/243 (20190101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/112 (20130101)
C12Q 2600/158 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 20/00 (20190201)
G16B 20/20 (20190201)
G16B 25/00 (20190201)
G16B 25/10 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174988 Matalanis et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
United States Army (USA)
APPLICANT(S) Sikorsky Aircraft Corporation (Stratford, Connecticut)
ASSIGNEE(S) SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut)
INVENTOR(S) Claude G. Matalanis (Longmeadow, Massachusetts);  Ulf J. Jonsson (South Windsor, Connecticut);  John D. Cannata (Marlborough, Connecticut);  Brian E. Wake (South Glastonbury, Connecticut)
ABSTRACT According to one aspect, a lubricant level sensing system for an actuator is provided. The lubricant level sensing system includes a pressure port in an outer housing of the actuator, a pressure sensor, and a pathway from the pressure port to the pressure sensor. The pathway establishes fluid communication between the pressure sensor and a free volume of an internal cavity of the outer housing relative to a lubricant level in the internal cavity such that the pressure sensor detects a pressure of the free volume used to derive the lubricant level.
FILED Monday, January 20, 2020
APPL NO 16/747133
ART UNIT 3654 — Material and Article Handling
CURRENT CPC
Aeroplanes; Helicopters
B64C 27/72 (20130101)
B64C 27/615 (20130101)
B64C 2027/7294 (20130101)

Lubricating
F16N 29/00 (20130101) Original (OR) Class
F16N 2250/04 (20130101)
F16N 2250/18 (20130101)

Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume
G01F 23/164 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11175118 Manley et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Secretary of the Army (SECARMY)
APPLICANT(S) U.S. Government as Represented by the Secretary of the Army (Dover, New Jersey)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) David Chalfant Manley (Budd Lake, New Jersey);  Thomas Michael Presutti, Jr. (Long Valley, New Jersey)
ABSTRACT A 40 millimeter (mm) projectile is capable of deploying a payload out of the rear of the projectile. The projectile carries the payload an extended distance from the muzzle and then disperses the payload after a command is provided to the projectile. The projectile includes a proximity fuze which allows it to sense a target and disperse the payload at a given distance from the target. Alternatively, a time-based fuze or radio frequency (RF) based fuze may be employed instead. The payload may be used against a variety of targets, such as personnel, vehicle or aerial targets. In addition, the projectile could be used as a training device for proximity, preprogrammed or RF-controlled fuzed projectiles.
FILED Wednesday, May 20, 2020
APPL NO 16/879329
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General
F41H 11/02 (20130101)
F41H 13/0006 (20130101)

Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 12/66 (20130101) Original (OR) Class

Ammunition Fuzes; Arming or Safety Means Therefor
F42C 9/00 (20130101)
F42C 13/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11175180 Fiordilino et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Surface Warfare Center (NSWC)
Secretary of the Navy (SECNAV)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Crane, Indiana)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Joseph A. Fiordilino (Pittsburgh, Pennsylvania);  Subrata Sanyal (Eastvale, California)
ABSTRACT The present invention relates to an optical energy meter. Illustrative embodiments of the present disclosure include a system controller, temperature sensing system, vibration sensing system, torque sensing system, graphical display system, climate control system, and vibration control system. The invention measures the radiation pressure of incident high power electromagnetic radiation. The measurement of radiation pressure can be used to determine the power of the radiation; that is, the purposes of the invention are to measure, with high precision and accuracy, and survive the power of an incident high power electromagnetic beam while minimizing size, weight, and power requirements.
FILED Thursday, June 14, 2018
APPL NO 16/008264
ART UNIT 2886 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 1/56 (20130101) Original (OR) Class
G01J 1/0252 (20130101)
G01J 1/0437 (20130101)

Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for
G01K 17/003 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11175191 Wall et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Walter W. Wall (Los Angeles, California);  Skyler Selvin (San Jose, California);  Geoffrey P. McKnight (Los Angeles, California);  Casey J. Sennott (Calabasas, California);  David W. Shahan (Malibu, California)
ABSTRACT A magnetic transmitting antenna has a beam member having a first end and a second end, wherein the beam member comprising: an elastic member; at least one magnetoelastic member disposed on a first surface of the elastic member; and an actuator disposed on a second surface of the elastic member, wherein the actuator is configured to apply stress to the elastic member thereby applying a bending stress thereto for changing the magnetic permeability of the at least one magnetoelastic member, which in turn, changes an external magnetic field. At least one magnet is disposed adjacent to the magnetoelastic member such that magnetization is induced in the magnetoelastic member.
FILED Wednesday, April 24, 2019
APPL NO 16/393830
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 1/125 (20130101) Original (OR) Class

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/09 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 41/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11175214 Williams et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) THE BOEING COMPANY (Chicago, Illinois)
ASSIGNEE(S) THE BOEING COMPANY (Chicago, Illinois)
INVENTOR(S) Kristen Smith Williams (Madison, Alabama);  Bruno Zamorano Senderos (Huntsville, Alabama);  David Adam Jackson (Madison, Alabama)
ABSTRACT In one aspect, an apparatus includes a chamber configured to control one or more of humidity, pressure, or temperature and a jaw configured to flex a material system. The chamber includes an enclosure disposed within the chamber, the enclosure having an insulating material, and a motor or an actuator disposed within the enclosure. The chamber includes an inlet tube coupled with the enclosure at a first end and a first wall of the chamber at a second end. In one aspect, a method for determining material performance includes exposing a material system to a relative humidity of from 0% to 98% and flexing the material system at a first temperature in a chamber, the chamber comprising an enclosure disposed within the chamber and a motor disposed within the enclosure. The method includes operating the motor at a second temperature different from the first temperature during the flexing.
FILED Tuesday, December 18, 2018
APPL NO 16/223285
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 17/002 (20130101) Original (OR) Class
G01N 17/006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11175441 Tabirian et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
U.S. Air Force
APPLICANT(S) Beam Engineering for Advanced Measurements Co. (Orlando, Florida)
ASSIGNEE(S) Beam Engineering for Advanced Measurements Co. (Orlando, Florida)
INVENTOR(S) Nelson V. Tabirian (Winter Park, Florida);  David E. Roberts (Apopka, Florida)
ABSTRACT Diffractive optical structures, lens, waveplates, systems and methods of combinations of CDWs (cycloidal diffractive waveplates) and PVGs (polarization volume gratings) that result in high efficiency polarization-insensitive diffraction. Although our modelling and experiments were performed for structures with optical axis orientation periodic along one of the Cartesian coordinates parallel to the plane of the structure, the results are applicable to more complex structures such as diffractive waveplate lenses. The focusing performance of such structures can be predicted by considering the structure to be locally periodic along one axis.
FILED Tuesday, March 05, 2019
APPL NO 16/293122
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 5/1833 (20130101) Original (OR) Class
G02B 5/1866 (20130101)
G02B 5/3025 (20130101)
G02B 5/3083 (20130101)
G02B 27/4205 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11175495 Watnik
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Secretary of the Navy (SECNAV)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Abbie T. Watnik (Washington, District of Columbia)
ABSTRACT An optical apparatus and method of using same. The optical apparatus includes a vortex optical isolator including an axis. The vortex optical isolator includes a first amplitude mask defining a first limiting aperture and aligned with the axis. The first limiting aperture includes a first radius. The vortex optical isolator includes a first lens aligned with the axis. The vortex optical isolator includes a vortex phase mask aligned with the axis. The vortex optical isolator includes a second lens aligned with the axis. The vortex optical isolator includes a second amplitude mask defining a second limiting aperture aligned with the axis. The second limiting aperture includes a second radius sufficiently smaller than the first radius so as to block reverse light traveling through the optical apparatus. The apparatus includes a standard light source configured to transmit forward light through the vortex optical isolator.
FILED Wednesday, June 12, 2019
APPL NO 16/438555
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 5/005 (20130101)
G02B 27/0018 (20130101) Original (OR) Class
G02B 27/286 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11175562 Skirlo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
U.S. Air Force
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Scott A. Skirlo (Boston, Massachusetts);  Cheryl Marie Sorace-Agaskar (Bedford, Massachusetts);  Marin Soljacic (Belmont, Massachusetts);  Simon Verghese (Arlington, Massachusetts);  Jeffrey S. Herd (Rowley, Massachusetts);  Paul William Juodawlkis (Arlington, Massachusetts);  Yi Yang (Cambridge, Massachusetts);  Dirk Englund (Brookline, Massachusetts);  Mihika Prabhu (Cambridge, Massachusetts)
ABSTRACT An integrated optical beam steering device includes a planar dielectric lens that collimates beams from different inputs in different directions within the lens plane. It also includes an output coupler, such as a grating or photonic crystal, that guides the collimated beams in different directions out of the lens plane. A switch matrix controls which input port is illuminated and hence the in-plane propagation direction of the collimated beam. And a tunable light source changes the wavelength to control the angle at which the collimated beam leaves the plane of the substrate. The device is very efficient, in part because the input port (and thus in-plane propagation direction) can be changed by actuating only log2 N of the N switches in the switch matrix. It can also be much simpler, smaller, and cheaper because it needs fewer control lines than a conventional optical phased array with the same resolution.
FILED Tuesday, April 07, 2020
APPL NO 16/842048
ART UNIT 2883 — Optics
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/4813 (20130101)
G01S 7/4814 (20130101)
G01S 7/4817 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/311 (20210101)
G02F 1/2955 (20130101)
G02F 1/3136 (20130101) Original (OR) Class
G02F 2201/02 (20130101)
G02F 2201/06 (20130101)
G02F 2201/302 (20130101)
G02F 2203/70 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11175563 Wong et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
U.S. Air Force
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Chee Wei Wong (Los Angeles, California);  Shu-Wei Huang (Los Angeles, California);  Abhinav Kumar Vinod (Los Angeles, California)
ABSTRACT Systems and methods in accordance with embodiments of the invention implement all-microwave stabilized microresonator-based optical frequency comb. In one embodiment, an all-microwave stabilized microresonator-based optical frequency comb includes: an optical pump configured to generate pulses of light; a microresonator including an input configured to receive pulses generated by an optical pump and an output configured to generate an optical frequency comb signal characterized by frep and ξ; where frep describes spacing of frequency components in the optical frequency comb; where the optical frequency comb includes a primary comb and a plurality of subcombs and ξ is a frequency offset between subcombs; and two phase locked loops that phase lock frep and ξ to low noise microwave oscillators by modulating output power and pump frequency of the optical pump.
FILED Thursday, August 17, 2017
APPL NO 16/326056
ART UNIT 2874 — Optics
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/3536 (20130101) Original (OR) Class
G02F 2203/15 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 5/14 (20130101)
H01S 5/0427 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11175584 Sierks et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S) Michael Sierks (Ft. McDowell, Arizona);  Stephanie Williams (Phoenix, Arizona)
ABSTRACT The present invention provides detection reagents and method for determining risk of traumatic brain injury (TBI), assessment of the amount of neuronal damage, and/or susceptibility to neurodegenerative disease in a subject.
FILED Tuesday, August 21, 2018
APPL NO 16/106699
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/47 (20130101)
C07K 2318/00 (20130101)
C07K 2319/70 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/11 (20130101)
C12N 15/62 (20130101)

Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor;
G03F 7/201 (20130101)
G03F 7/2004 (20130101) Original (OR) Class
G03F 7/2022 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11175649 Cunningham et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
U.S. Air Force
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Robert Cunningham (Lexington, Massachusetts);  Benjamin Kaiser (Cambridge, Massachusetts);  Margaret Boning (Cambridge, Massachusetts);  Jeffrey Brandon (Cambridge, Massachusetts);  Alice Lee (Cambridge, Massachusetts)
ABSTRACT A method for mediating an interaction between a control station and a remote system includes maintaining, at a command monitor, data characterizing an operation of the remote system in response to execution of commands at the remote system, receiving, at the command monitor, state information from the remote system, updating the data characterizing the operation of the remote system based on the received state information, receiving, at the command monitor, one or more commands sent from the control station, determining a predicted set of one or more outcomes that would result from execution of the one or more commands at the remote system based at least in part on the data characterizing the operation of the remote system, and preventing issuance of at least one command of the one or more commands at the remote system based on the predicted set of one or more outcomes.
FILED Tuesday, July 03, 2018
APPL NO 16/026266
ART UNIT 2412 — Multiplex and VoIP
CURRENT CPC
Cosmonautics; Vehicles or Equipment Therefor
B64G 1/10 (20130101)
B64G 1/24 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 19/02 (20130101)

Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 19/41835 (20130101) Original (OR) Class
G05B 19/41855 (20130101)
G05B 19/41885 (20130101)
G05B 2219/25274 (20130101)

Transmission
H04B 7/155 (20130101)
H04B 7/185 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/0825 (20130101)
H04L 9/3273 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11176150 Mirhaji
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Parsa Mirhaji (Pearland, Texas)
ABSTRACT Embodiments of methods and systems for informatics systems are disclosed. Such informatics systems may utilize a unifying format to represent text to facilitate linking between data from the text and one or more ontologies, and the commensurate ability to mine such data.
FILED Wednesday, August 14, 2019
APPL NO 16/540823
ART UNIT 2165 — Data Bases & File Management
CURRENT CPC
Electric Digital Data Processing
G06F 16/22 (20190101)
G06F 16/248 (20190101)
G06F 16/367 (20190101)
G06F 16/2465 (20190101) Original (OR) Class
G06F 16/3329 (20190101)
G06F 16/3344 (20190101)
G06F 16/9024 (20190101)
G06F 40/211 (20200101)
G06F 40/253 (20200101)
G06F 40/284 (20200101)
G06F 40/289 (20200101)

Computer Systems Based on Specific Computational Models
G06N 5/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11176361 Young et al.
FUNDED BY
Department of Defense (DOD)
Assistant Secretary of Defense for Special Operations/Low-Intensity Conflict (ASD SOLIC)
Combating Terrorism Technical Support Office (CTTSO)
APPLICANT(S) Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Darrell L. Young (Falls Church, Virginia);  Kevin C. Holley (Reston, Virginia)
ABSTRACT Disclosed are methods for handwriting recognition. In some aspects, an image representing a page of a sample document is analyzed to identify a region having indications of handwriting. The region is analyzed to determine frequencies of a plurality of geometric features within the region. The frequencies may be compared to profiles or histograms of known language types, to determine if there are similarities between the frequencies in the sample document relative to those of the known language types. In some aspects, machine learning may be used to characterize the document as a particular language type based on the frequencies of the geometric features.
FILED Friday, June 21, 2019
APPL NO 16/448883
ART UNIT 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Electric Digital Data Processing
G06F 40/263 (20200101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00409 (20130101) Original (OR) Class
G06K 9/00416 (20130101)
G06K 9/6256 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11176370 Mendoza-Schrock
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Secretary of the Air Force (SECAF)
APPLICANT(S) Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Olga Mendoza-Schrock (Kettering, Ohio)
ABSTRACT A method, computer program product, and customized image processing system provide aided target recognition (AiTR) using manifold transfer substance learning (MTSL). The method includes receiving image data. The method includes performing manifold learning technique comprising diffusion mapping on the received image data to transform the received image data. The method includes applying a transfer subspace learning technique comprising Transfer Fishers Linear Discriminative Analysis (TrFLDA) to the transformed data to recognize an object within the image data.
FILED Sunday, June 30, 2019
APPL NO 16/458126
ART UNIT 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/0063 (20130101) Original (OR) Class
G06K 9/6234 (20130101)
G06K 2209/21 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11176445 Esser et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Steve Kyle Esser (San Jose, California);  Dharmendra S. Modha (San Jose, California);  Anthony Ndirango (Berkeley, California)
ABSTRACT Embodiments of the invention relate to canonical spiking neurons for spatiotemporal associative memory. An aspect of the invention provides a spatiotemporal associative memory including a plurality of electronic neurons having a layered neural net relationship with directional synaptic connectivity. The plurality of electronic neurons configured to detect the presence of a spatiotemporal pattern in a real-time data stream, and extract the spatiotemporal pattern. The plurality of electronic neurons are further configured to, based on learning rules, store the spatiotemporal pattern in the plurality of electronic neurons, and upon being presented with a version of the spatiotemporal pattern, retrieve the stored spatiotemporal pattern.
FILED Friday, April 21, 2017
APPL NO 15/494343
ART UNIT 2198 — Graphical User Interface and Document Processing
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 3/049 (20130101) Original (OR) Class
G06N 3/063 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11176446 Amir et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Arnon Amir (Saratoga, California);  Pallab Datta (San Jose, California);  Dharmendra S. Modha (San Jose, California);  Benjamin G. Shaw (San Francisco, California)
ABSTRACT Embodiments of the invention provide a method comprising maintaining a library of one or more compositional prototypes. Each compositional prototype is associated with a neurosynaptic program. The method further comprises searching the library based on one or more search parameters. At least one compositional prototype satisfying the search parameters is selected. A neurosynaptic network is generated or extended by applying one or more rules associated with the selected compositional prototypes.
FILED Friday, March 16, 2018
APPL NO 15/924054
ART UNIT 2122 — AI & Simulation/Modeling
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/049 (20130101)
G06N 3/063 (20130101) Original (OR) Class
G06N 3/082 (20130101)
G06N 3/105 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11177563 Bermeo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Information Warfare Center (NIWC)
Secretary of the Navy (SECNAV)
APPLICANT(S) Naval Information Warfare Center, Pacific (San Diego, California)
ASSIGNEE(S) United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Dennis G. Bermeo (San Diego, California);  Peter S. Berens (San Diego, California);  David W. Brock (San Diego, California);  Christopher C. Obra (San Diego, California);  Jessica L. Watson (Santee, California);  Hoin Lim (Lihue, Hawaii)
ABSTRACT A lower element ground plane apparatus for maximizing ground plane surface area in an antenna system, the apparatus involving a lower element of a bi-element antenna and an array of monopole antennas coupled with the lower element of the bi-element antenna, the lower element of the bi-element antenna operable as a ground plane for the array of monopole antennas, whereby ground plane surface area is maximized.
FILED Thursday, August 15, 2019
APPL NO 16/541384
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 1/48 (20130101) Original (OR) Class
H01Q 1/52 (20130101)
H01Q 13/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11177622 Gord et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Secretary of the Air Force (SECAF)
APPLICANT(S) James R. Gord (Dayton, Ohio);  Paul S Hsu (Dayton, Ohio);  Sukesh Roy (Beavercreek, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) James R. Gord (Dayton, Ohio);  Paul S Hsu (Dayton, Ohio);  Sukesh Roy (Beavercreek, Ohio)
ABSTRACT A low-repetition-rate (10-Hz), picosecond (ps) optical parametric generator (OPG) system produces higher energy output levels in a more robust and reliable system than previously available. A picosecond OPG stage is seeded at an idler wavelength with a high-power diode laser and its output at ˜566 nm is amplified in a pulsed dye amplifier (PDA) stage having two dye cells, resulting in signal enhancement by more than three orders of magnitude. The nearly transform-limited beam at ˜566 nm has a pulse width of ˜170 ps with an overall output of ˜2.3 mJ/pulse. A spatial filter between the OPG and PDA stages and a pinhole between the two dye cells improve high output beam quality and enhances coarse and fine wavelength tuning capability.
FILED Monday, July 23, 2012
APPL NO 13/555198
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/392 (20210101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/11 (20130101)
H01S 3/213 (20130101)
H01S 3/0805 (20130101)
H01S 3/1083 (20130101) Original (OR) Class
H01S 3/10007 (20130101)
H01S 3/10023 (20130101)
H01S 3/10084 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11178314 Robison et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army
APPLICANT(S) BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
ASSIGNEE(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S) Derek T Robison (Acton, Massachusetts);  Brendan P. Cirillo (Merrimack, New Hampshire)
ABSTRACT A system for suppressing sight blooming in an infrared sight includes determining an n×n grid size; creating a grid of n×n averages; calculating a mean; determining if a heat source is detected; detecting a heat source radius; calculating the average of the outside boxes; estimating the average of the inside boxes; setting the source to zero; smoothing the boxes; subtracting the mean of the outside from the mean of the inside; feeding back the result into history; up-sampling the offset; subtracting the offsets; and displaying the image.
FILED Wednesday, December 05, 2018
APPL NO 16/210792
ART UNIT 2872 — Optics
CURRENT CPC
Weapon Sights; Aiming
F41G 1/01 (20130101)
F41G 1/02 (20130101)
F41G 1/36 (20130101)

Image Data Processing or Generation, in General
G06T 5/002 (20130101)
G06T 5/50 (20130101)
G06T 7/62 (20170101)
G06T 2207/10048 (20130101)
G06T 2207/20021 (20130101)
G06T 2207/20192 (20130101)
G06T 2207/20224 (20130101)
G06T 2207/30212 (20130101)

Pictorial Communication, e.g Television
H04N 5/33 (20130101)
H04N 5/217 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11178349 Sankaranarayanan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) William Marsh Rice University (Houston, Texas)
ASSIGNEE(S) William Marsh Rice University (Houston, Texas)
INVENTOR(S) Aswin Sankaranarayanan (Houston, Texas);  Ashok Veeraraghavan (Houston, Texas);  Lisa A. Hendricks (Houston, Texas);  Richard Baraniuk (Houston, Texas);  Ali Ayremlou (Houston, Texas);  M. Salman Asif (Houston, Texas)
ABSTRACT A lens-free imaging system for generating an image of a scene includes an electromagnetic (EM) radiation sensor; a mask disposed between the EM radiation sensor and the scene; an image processor that obtains signals from the EM radiation sensor while the EM radiation sensor is exposed to the scene; and estimates the image of the scene based on, at least in part, the signals and a transfer function between the scene and the EM radiation sensor.
FILED Friday, January 29, 2016
APPL NO 15/547235
ART UNIT 2698 — Selective Visual Display Systems
CURRENT CPC
Measurement of Nuclear or X-radiation
G01T 1/295 (20130101)

Optical Elements, Systems, or Apparatus
G02B 27/42 (20130101)
G02B 2207/129 (20130101)

Pictorial Communication, e.g Television
H04N 5/30 (20130101)
H04N 5/225 (20130101)
H04N 5/378 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 11172839 Ward et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Kevin R. Ward (Superior Township, Michigan);  Sardar Ansari (Richmond, Virginia);  Lu Wang (Ann Arbor, Michigan);  Kayvan Najarian (Northville, Michigan);  Kenn Oldham (Ann Arbor, Michigan)
ABSTRACT A wearable assembly has a pulse plethysmography (PPG) sensor and a piezoelectric pressure sensor and is attachable to a patient's finger or other area corresponding to a peripheral vascular region, and further includes a signal processor configured to monitor blood flow dependent measurements and pressure measurements over time, comparing these measurements to determine properties of the vascular region, such as vascular resistance of a blood vessel, vascular radius of the blood vessel, vascular stiffness of the vascular region, blood pressure, and/or cardiac vascular power. The signal processor may apply a hysteresis comparison of the sensor outputs, e.g., using an elliptical model, and in some examples may apply an extended Kalman filter for optimizing output of the vascular region properties.
FILED Wednesday, October 25, 2017
APPL NO 16/344671
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0295 (20130101) Original (OR) Class
A61B 5/1455 (20130101)
A61B 5/02007 (20130101)
A61B 5/02255 (20130101)
A61B 2562/0247 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173119 Fahmy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
U.S. Public Health Service (USPHS)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S) YALE UNIVERSITY (New Haven, Connecticut)
ASSIGNEE(S) Yale University (New Haven, Connecticut)
INVENTOR(S) Tarek M. Fahmy (New Haven, Connecticut);  Eric Stern (Jamaica Plain, Massachusetts);  Richard A. Flavell (Guillford, Connecticut);  Jason Park (New York, New York);  Alyssa Siefert (Naugatuck, Connecticut);  Stephen H. Wrzesinski (Slingerlands, New York)
ABSTRACT A “nanolipogel” is a delivery vehicle including one or more lipid layer surrounding a hydrogel core, which may include an absorbent such as a cyclodextrin or ion-exchange resin. Nanolipogels can be constructed so as to incorporate a variety of different chemical entities that can subsequently be released in a controlled fashion. These different incorporated chemical entities can differ dramatically with respect to size and composition. Nanolipogels have been constructed to contain co-encapsulated proteins as well as small hydrophobic drugs within the interior of the lipid bilayer. Agents incorporated within nanolipogels can be released into the milieu in a controlled fashion, for example, nanolipogels provide a means of achieving simultaneous sustained release of agents that differ widely in chemical composition and molecular weight. Additionally, nanolipogels can favorably modulate biodistribution.
FILED Thursday, December 12, 2019
APPL NO 16/711591
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/127 (20130101) Original (OR) Class
A61K 9/1271 (20130101)
A61K 9/1273 (20130101)
A61K 9/1277 (20130101)
A61K 9/5153 (20130101)
A61K 31/343 (20130101)
A61K 38/1841 (20130101)
A61K 38/2013 (20130101)
A61K 47/24 (20130101)
A61K 47/40 (20130101)
A61K 47/58 (20170801)
A61K 47/6849 (20170801)
A61K 47/6937 (20170801)
A61K 47/6951 (20170801)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)

Peptides
C07K 16/2812 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173227 Yang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania);  BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S) THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania);  BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Jian Yang (State College, Pennsylvania);  Kytai T. Nguyen (Grand Prairie, Texas);  Zhiwei Xie (State College, Pennsylvania)
ABSTRACT In one aspect, compositions and wound dressings are described herein. In some embodiments, a composition or wound dressing described herein comprises a mesh formed from a plurality of biodegradable polymer fibers; a first active agent dispersed in the biodegradable polymer fibers; a plurality of biodegradable polymer particles disposed in the mesh; and a second active agent dispersed in the biodegradable polymer particles. The particles can be disposed within the interiors of the fibers of the mesh or between the fibers of the mesh. In another aspect, a composition or wound dressing described herein comprises a first perforated mesh formed from a first plurality of biodegradable polymer fibers; and a second perforated mesh formed from a second plurality of biodegradable polymer fibers, wherein the second perforated mesh is disposed on the first perforated mesh in a stacked configuration and the first and second perforated meshes have different degrees of perforation.
FILED Wednesday, May 21, 2014
APPL NO 14/891862
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 15/26 (20130101)
A61L 15/26 (20130101)
A61L 15/28 (20130101)
A61L 15/28 (20130101)
A61L 15/28 (20130101)
A61L 15/44 (20130101)
A61L 15/64 (20130101)
A61L 15/225 (20130101) Original (OR) Class
A61L 15/425 (20130101)
A61L 31/06 (20130101)
A61L 31/06 (20130101)
A61L 31/16 (20130101)
A61L 31/042 (20130101)
A61L 31/042 (20130101)
A61L 31/042 (20130101)
A61L 31/129 (20130101)
A61L 31/129 (20130101)
A61L 31/129 (20130101)
A61L 31/129 (20130101)
A61L 31/129 (20130101)
A61L 31/146 (20130101)
A61L 31/148 (20130101)
A61L 2300/45 (20130101)
A61L 2300/252 (20130101)
A61L 2300/404 (20130101)
A61L 2300/414 (20130101)
A61L 2300/604 (20130101)
A61L 2300/624 (20130101)

Compositions of Macromolecular Compounds
C08L 1/26 (20130101)
C08L 1/26 (20130101)
C08L 1/26 (20130101)
C08L 5/08 (20130101)
C08L 5/08 (20130101)
C08L 5/08 (20130101)
C08L 67/04 (20130101)
C08L 67/04 (20130101)
C08L 71/02 (20130101)
C08L 71/02 (20130101)
C08L 71/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174277 Zhu et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
Alliance for Sustainable Energy, LLC (ASE)
National Renewable Energy Laboratory (NREL)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  Board of Trustees of Northern Illinois University (DeKalb, Illinois)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) Kai Zhu (Littleton, Colorado);  Tao Xu (Naperville, Illinois)
ABSTRACT The present disclosure relates to a composition that includes a sequestering material capable of binding a target material, where the sequestering material includes a first component that includes at least one of a functional group, a molecule, an oligomer, or a polymer, and the target material includes at least one of an element, a chemical, and/or a compound. In some embodiments of the present disclosure, the element may include at least one element from at least one of Rows 4, 5, 6, and 7 of the Periodic Table and/or an inner transition metal.
FILED Wednesday, January 08, 2020
APPL NO 16/736958
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/3873 (20130101)
C07F 9/4006 (20130101) Original (OR) Class

Compositions of Macromolecular Compounds
C08L 71/02 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/042 (20130101)

Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules
H02S 40/38 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174325 Fantin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania)
ASSIGNEE(S) CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania)
INVENTOR(S) Marco Fantin (Pittsburgh, Pennsylvania);  Pawel Chmielarz (Pittsburgh, Pennsylvania);  Yi Wang (Pittsburgh, Pennsylvania);  Francesca Lorandi (Pittsburgh, Pennsylvania);  Krzysztof Matyjaszewski (Pittsburgh, Pennsylvania)
ABSTRACT Systems and methods for Atom Transfer Radical Polymerization (ATRP) emulsion polymerization are provided. The ATRP emulsion polymerization comprises a suspending medium, a dispersed medium, a surfactant, a transition metal compound in a higher oxidation state, a ligand, and an ATRP initiator. The transition metal compound is capable of forming a catalyst complex in a presence of the ligand. The catalyst complex is soluble in the suspending medium and is capable of forming an ionic complex with the surfactant. The ionic complex is capable of moving between the suspending medium and the dispersed medium. A portion of the transition metal compound in the higher oxidation state within a portion of the catalyst complex is reduced by a physical and/or a chemical procedure thereby initiating a polymerization of one or more radically (co)polymerizable monomers by reaction with the initiator.
FILED Thursday, January 11, 2018
APPL NO 16/475886
ART UNIT 1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 2/26 (20130101)
C08F 2/38 (20130101) Original (OR) Class
C08F 4/10 (20130101)
C08F 4/40 (20130101)
C08F 220/18 (20130101)
C08F 2438/01 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174353 Old et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army
Army Research Office (ARO)
Subcellular Pan-Omics for Advanced Rapid Threat Assessment (SPARTA)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado)
ASSIGNEE(S) The Regents of the University of Colorado (Denver, Colorado)
INVENTOR(S) William Old (Denver, Colorado);  Douglas A. Chapnick (Boulder, Colorado);  Tristan D. McClure-Begley (Lafayette, Colorado);  Tao Gong (Superior, Colorado);  Brady Worrell (Boulder, Colorado);  Christopher C. Ebmeier (Arvada, Colorado);  Christopher Bowman (Boulder, Colorado)
ABSTRACT Crosslinking compounds for effective and efficient cross-linking and identification of intermolecular and intramolecular interactions of proteins, peptides and nucleic acids.
FILED Tuesday, March 05, 2019
APPL NO 16/293191
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Derivatives of Natural Macromolecular Compounds
C08H 1/00 (20130101) Original (OR) Class

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 5/10 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6848 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174404 Youngblood et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Jeffrey Paul Youngblood (Crawfordsville, Indiana);  Reaz Chowdhury (West Lafayette, Indiana);  Md Nuruddin (West Lafayette, Indiana)
ABSTRACT The present application relates to a novel method of large scale continuous roll-to-roll fabrication of cellulose nanocrystal (CNC) coatings with controlled anisotropy, and the cellulose nanocrystal (CNC) coated flexible substrate prepared with the novel method. An unexpectedly high order parameter of 0.78 is observed when in CNC-PVA composite at 70% CNC loading.
FILED Tuesday, September 04, 2018
APPL NO 16/643034
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 11/14 (20130101) Original (OR) Class
C09D 11/106 (20130101)
C09D 101/02 (20130101)
C09D 129/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174571 Parker et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Kevin Kit Parker (Cambridge, Massachusetts);  Grant Michael Gonzalez (Somerville, Massachusetts);  Holly M. Golecki (Urbana, Illinois);  Kwanwoo Shin (Rogers, Arkansas);  Josue A. Goss (Cambridge, Massachusetts)
ABSTRACT Exemplary embodiments provide systems, devices and methods for the fabrication of three-dimensional polymeric fibers having micron, submicron and nanometer dimensions, as well as methods of use of the polymeric fibers.
FILED Monday, November 11, 2019
APPL NO 16/679578
ART UNIT 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 5/18 (20130101)
C08J 2377/10 (20130101)

Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons
D01D 5/06 (20130101)
D01D 5/18 (20130101) Original (OR) Class

Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments
D01F 6/605 (20130101)
D01F 9/00 (20130101)

Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles
D10B 2331/021 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/249921 (20150401)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11175222 Cunningham et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Brian T. Cunningham (Champaign, Illinois);  John Michael Dallesasse (Geneva, Illinois)
ABSTRACT The present disclosure describes the design, fabrication, and demonstration of a compact spectroscopic analysis system that utilizes a linear variable filter chip attached directly over an image sensor array, and an integrated broadband LED illuminator that supplies light from the edge of the system to provide a low vertical dimension. The instrument is capable of accurately measuring the optical absorption spectra of colored liquids or the scattered spectra from solid objects that are placed in the illumination pathway. Due to the small vertical thickness of the system, the low cost of its components, and the accuracy with which it renders spectra in comparison to conventional spectrometers, we envision potential incorporation of the system into mobile communication devices, such as smartphones and tablets, as a means for providing a dedicated sensor for health diagnostic, environmental monitoring, and general-purpose color sensing applications.
FILED Thursday, November 15, 2018
APPL NO 16/191732
ART UNIT 2877 — Optics
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5027 (20130101)
B01L 3/5085 (20130101)
B01L 2200/025 (20130101)
B01L 2300/06 (20130101)
B01L 2300/0609 (20130101)
B01L 2300/0829 (20130101)
B01L 2300/0877 (20130101)

Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/46 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/27 (20130101)
G01N 21/255 (20130101) Original (OR) Class
G01N 2201/062 (20130101)
G01N 2201/0221 (20130101)
G01N 2201/0627 (20130101)
G01N 2201/0636 (20130101)

Telephonic Communication
H04M 1/0264 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11175244 Perry et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Sarah L. Perry (Belchertown, Massachusetts);  Shou Sui (Amherst, Massachusetts)
ABSTRACT The invention provides a novel microfluidic platform for use in electro-crystallization and electro-crystallography experiments. The manufacturing and use of graphene as X-ray compatible electrodes allows the application of electric fields on-chip, during X-ray analysis. The presence of such electric fields can be used to modulate the structure of protein (or other) molecules in crystalline (for X-ray diffraction) or solution form (for X-ray scattering). Additionally, the presence of an electric field can be used to extend the lifetime of fragile samples by expediting the removal of reactive secondary radiation damage species.
FILED Tuesday, June 18, 2019
APPL NO 16/444240
ART UNIT 2884 — Optics
CURRENT CPC
Separation
B01D 9/0072 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/06 (20130101)
B01L 3/502707 (20130101)
B01L 3/502761 (20130101)
B01L 2200/10 (20130101)

Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 7/14 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/20 (20130101)
G01N 23/22 (20130101)
G01N 23/201 (20130101)
G01N 23/203 (20130101)
G01N 23/205 (20130101)
G01N 23/207 (20130101)
G01N 23/223 (20130101)
G01N 23/2076 (20130101)
G01N 23/2202 (20130101)
G01N 23/2204 (20130101)
G01N 23/2206 (20130101)
G01N 23/2208 (20130101)
G01N 23/2209 (20180201)
G01N 23/20008 (20130101)
G01N 23/20025 (20130101) Original (OR) Class
G01N 23/20066 (20130101)
G01N 23/20083 (20130101)
G01N 23/20091 (20130101)
G01N 27/26 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11175306 Marohn et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) CORNELL UNIVERSITY (Ithaca, New York)
ASSIGNEE(S) CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S) John Marohn (Ithaca, New York);  Sarah Nathan (Ithaca, New York);  Ryan Dwyer (Pewaukee, Wisconsin)
ABSTRACT Atomic force microscopy apparatus and method that enable observing charge generation transients with nanometer spatial resolution and nanosecond to picosecond time resolution, the timescale relevant for studying photo-generated charges in the world's highest efficiency photovoltaic films. The AFM apparatus includes an AFM, a light source for illumination of a sample operatively coupled to the AFM, a voltage source operatively coupled to the AFM, and a control circuitry operatively coupled to the light source and the voltage source. The AFM apparatus improves the time resolution and enables rapid acquisition of photocapacitance transients in a wide array of solar-energy-harvesting materials.
FILED Thursday, May 10, 2018
APPL NO 16/612473
ART UNIT 2881 — Optics
CURRENT CPC
Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM]
G01Q 30/00 (20130101) Original (OR) Class
G01Q 60/30 (20130101)
G01Q 60/48 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11175544 Yang et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Canhui Yang (Somerville, Massachusetts);  Shuang Zhou (Somerville, Massachusetts);  Zhigang Suo (Lexington, Massachusetts)
ABSTRACT A stretchable electrooptical device includes a liquid crystal cell disposed between first and second ionic conducting gel layers; and first and second electronic conductors in electrical contact with the first and second ionic conducting gel layers, respectively, said first and second electronic conductors connectable to an external voltage source.
FILED Wednesday, March 07, 2018
APPL NO 16/491106
ART UNIT 2871 — Optics
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/0018 (20130101)
G02F 1/061 (20130101)
G02F 1/1525 (20130101)
G02F 1/13439 (20130101) Original (OR) Class
G02F 1/15165 (20190101)
G02F 1/133305 (20130101)

Arrangements or Circuits for Control of Indicating Devices Using Static Means to Present Variable Information
G09G 3/3655 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/0565 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11175641 Chiang et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Cornell University (Ithaca, New York)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) Hsiao-Dong Chiang (Ithaca, New York);  Tao Wang (Ithaca, New York)
ABSTRACT An apparatus comprises at least one processing device comprising a processor coupled to a memory. The at least one processing device is configured to obtain a system of nonlinear equations characterizing a physical system, to construct a flexible embedded system from the system of nonlinear equations, wherein the flexible embedded system is configurable with any of a plurality of arbitrary reference states as respective starting points, to utilize the flexible embedded system to generate at least one output providing a solution to the system of nonlinear equations, and to establish one or more operating parameters of the physical system based at least in part on the output generated utilizing the flexible embedded system. The physical system is configured in accordance with the one or more established operating parameters. The physical system in some embodiments illustratively comprises an electric power system, an integrated circuit, or another type of electrical or electronic system or circuit.
FILED Friday, July 26, 2019
APPL NO 16/523648
ART UNIT 2115 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 19/042 (20130101) Original (OR) Class
G05B 2219/2639 (20130101)

Electric Digital Data Processing
G06F 17/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11176082 Novotny
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Mark A. Novotny (Starkville, Mississippi)
ASSIGNEE(S) Mississippi State University (Mississippi State, Mississippi)
INVENTOR(S) Mark A. Novotny (Starkville, Mississippi)
ABSTRACT Computer architecture methods and system for providing novel inhomogeneous computer interconnects and interconnect topology framework for both classical and quantum computers are provided that result in enhanced computer functionality and efficiency. The architecture and methodologies include random small world (SW) interconnects or bonds and/or SW interconnects or bonds with constrained randomness.
FILED Tuesday, October 27, 2015
APPL NO 15/522359
ART UNIT 2128 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 15/8007 (20130101) Original (OR) Class
G06F 30/394 (20200101)

Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11176289 Abur et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) NORTHEASTERN UNIVERSITY (Boston, Massachusetts)
ASSIGNEE(S) Northeastern University (Boston, Massachusetts)
INVENTOR(S) Ali Abur (Brookline, Massachusetts);  Yuzhang Lin (Boston, Massachusetts)
ABSTRACT Techniques and apparatus for parameter error detection in a power system based on state estimation are described. In one embodiment, for example, an efficient process may be used to derive and compute only the necessary subset of the gain matrix and covariance matrix, thus avoiding the computation and storage of large dense matrices. The described efficient process can be applied either to single-scan or multiple-scan schemes. Other embodiments are described.
FILED Monday, August 13, 2018
APPL NO 16/102420
ART UNIT 2127 — AI & Simulation/Modeling
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 19/2513 (20130101)

Electric Digital Data Processing
G06F 11/00 (20130101)
G06F 17/16 (20130101)
G06F 17/18 (20130101)
G06F 30/20 (20200101) Original (OR) Class
G06F 2111/10 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11176377 Nandi et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Ohio State Innovation Foundation (Columbus, Ohio)
ASSIGNEE(S) Ohio State Innovation Foundation (Columbus, Ohio)
INVENTOR(S) Arnab Nandi (Columbus, Ohio);  Codi Burley (Grove City, Ohio)
ABSTRACT The exemplified system and method facilitates process, grammar, and framework to perform analytics operations, and visualize the result of analytics operations using augmented reality. The exemplified system and method can be used, but is not limited to, for augmented reality presentations of physical objects as paper documents, digital or printed signage, posters, physical or digital displays, real-world objects, indoor and outdoor spaces, hardware device displays, vehicle dashboards, and other real-world scenes.
FILED Wednesday, September 09, 2020
APPL NO 17/015276
ART UNIT 2175 — Graphical User Interface and Document Processing
CURRENT CPC
Electric Digital Data Processing
G06F 3/017 (20130101)
G06F 3/0484 (20130101)
G06F 3/04815 (20130101)
G06F 9/451 (20180201)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00449 (20130101)
G06K 9/00671 (20130101) Original (OR) Class
G06K 2209/01 (20130101)

Image Data Processing or Generation, in General
G06T 7/246 (20170101)
G06T 19/006 (20130101)
G06T 2207/10016 (20130101)
G06T 2207/20164 (20130101)
G06T 2207/30176 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11176631 Tu et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida)
ASSIGNEE(S) UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida)
INVENTOR(S) Yicheng Tu (Tampa, Florida);  Zhila Nouri Lewis (Tampa, Florida)
ABSTRACT Disclosed are various embodiments for GPU-based parallel indexing for concurrent spatial queries. A number of nodes in a tree to be partitioned is determined. The tree is then iteratively partitioned with the GPU. Nodes are created with the GPU. Finally, a point insertion is performed using the GPU.
FILED Tuesday, June 25, 2019
APPL NO 16/451295
ART UNIT 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Electric Digital Data Processing
G06F 9/3877 (20130101)
G06F 9/5061 (20130101)

Image Data Processing or Generation, in General
G06T 1/20 (20130101) Original (OR) Class
G06T 17/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11176960 Traynor et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S) Patrick G. Traynor (Gainesville, Florida);  Logan E. Blue (Gainesville, Florida);  Luis Vargas (Gainesville, Florida)
ABSTRACT A system for distinguishing between a human voice generated command and an electronic speaker generated command is provided. An exemplary system comprises a microphone array for receiving an audio signal collection, preprocessing circuitry configured for converting the audio signal collection into processed recorded audio signals, energy balance metric determination circuitry configured for calculating a final energy balance metric based on the processed recorded audio signals, and energy balance metric evaluation circuitry for outputting a command originator signal based at least in part on the final energy balance metric.
FILED Tuesday, June 18, 2019
APPL NO 16/444893
ART UNIT 2659 — Linguistics, Speech Processing and Audio Compression
CURRENT CPC
Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding
G10L 15/22 (20130101)
G10L 21/0232 (20130101)
G10L 21/0316 (20130101)
G10L 25/18 (20130101)
G10L 25/21 (20130101)
G10L 25/69 (20130101) Original (OR) Class
G10L 2015/223 (20130101)

Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems
H04R 1/406 (20130101)
H04R 3/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11176979 Wang et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Jian-Ping Wang (Minneapolis, Minnesota);  Sachin S. Sapatnekar (Minneapolis, Minnesota);  Ulya R. Karpuzcu (Minneapolis, Minnesota);  Zhengyang Zhao (Minneapolis, Minnesota);  Masoud Zabihi (Minneapolis, Minnesota);  Michael Salonik Resch (Minneapolis, Minnesota);  Zamshed I. Chowdhury (Minneapolis, Minnesota);  Thomas Peterson (Minneapolis, Minnesota)
ABSTRACT A logic-memory cell includes a spin-orbit torque device having first, second and third terminals configured such that current between the second and third terminals is capable of changing a resistance between the first and second terminals. In the cell, a first transistor is connected between a logic connection line and the first terminal of the spin-orbit torque device and a second transistor is connected between the logic connection line and the third terminal of the spin-orbit torque device.
FILED Thursday, February 27, 2020
APPL NO 16/803454
ART UNIT 2827 — Semiconductors/Memory
CURRENT CPC
Static Stores
G11C 11/161 (20130101) Original (OR) Class
G11C 11/1659 (20130101)
G11C 11/1673 (20130101)
G11C 11/1675 (20130101)
G11C 11/1697 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11177122 Jarrold et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana)
ASSIGNEE(S) The Trustees Of Indiana University (Bloomington, Indiana)
INVENTOR(S) Martin F. Jarrold (Bloomington, Indiana);  Andrew W. Alexander (Bloomington, Indiana);  Aaron R. Todd (Bloomington, Indiana)
ABSTRACT A CDMS may include an ELIT having a charge detection cylinder (CD), a charge generator for generating a high frequency charge (HFC), a charge sensitive preamplifier (CP) having an input coupled to the CD and an output configured to produce a charge detection signal (CHD) in response to a charge induced on the CD, and a processor configured to (a) control the charge generator to induce an HFC on the CD, (b) control operation of the ELIT to cause a trapped ion to oscillate back and forth through the CD each time inducing a charge thereon, and (c) process CHD to (i) determine a gain factor as a function of the HFC induced on the CD, and (ii) modify a magnitude of the portion of CHD resulting from the charge induced on the CD by the trapped ion passing therethrough as a function of the gain factor.
FILED Tuesday, June 04, 2019
APPL NO 17/058553
ART UNIT 2881 — Optics
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 49/0009 (20130101)
H01J 49/022 (20130101)
H01J 49/025 (20130101) Original (OR) Class
H01J 49/4245 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11177400 Welser et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
Small Business Administration (SBA)
Small Business Technology Transfer (STTR)
APPLICANT(S) Magnolia Optical Technologies, Inc. (Woburn, Massachusetts)
ASSIGNEE(S) Magnolia Optical Technologies, Inc. (Woburn, Massachusetts)
INVENTOR(S) Roger E. Welser (Providence, Rhode Island);  Ashok K. Sood (Brookline, Massachusetts)
ABSTRACT Refractive optical element designs are provided for high geometric optical efficiency over a wide range of incident angles. To minimize Fresnel reflection losses, the refractive optical element designs employ multiple encapsulant materials, differing in refractive index. Concentrator photovoltaic subassemblies are formed by embedding a high efficiency photovoltaic device within the refractive optical element, along with appropriate electrical contacts and heat sinks. Increased solar electric power output is obtained by employing a single-junction III-V material structure with light-trapping structures.
FILED Monday, September 18, 2017
APPL NO 15/708057
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/0232 (20130101) Original (OR) Class
H01L 31/0543 (20141201)
H01L 31/0547 (20141201)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11177902 Chacko et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
Directorate for Education and Human Resources (EHR)
Division of Undergraduate Education (DUE)
APPLICANT(S) Drexel University (Philadelphia, Pennsylvania)
ASSIGNEE(S) Drexel University (Philadelphia, Pennsylvania)
INVENTOR(S) James J. Chacko (Huntingdon Valley, Pennsylvania);  Kapil R. Dandekar (Philadelphia, Pennsylvania);  Marko Jacovic (Philadelphia, Pennsylvania);  Kyle Joseph Juretus (Quakertown, Pennsylvania);  Nagarajan Kandasamy (Philadelphia, Pennsylvania);  Cem Sahin (Peoria, Arizona);  Ioannis Savidis (Wallingford, Pennsylvania)
ABSTRACT A physical layer based technique secures wireless communication between a transmitter and receiver. The technique involves obfuscating the preamble data of the baseband signal through unique keys that are generated at the transmitter and the receiver based on channel characteristics known only to them.
FILED Monday, January 15, 2018
APPL NO 16/478148
ART UNIT 2491 — Cryptography and Security
CURRENT CPC
Secret Communication; Jamming of Communication
H04K 1/00 (20130101) Original (OR) Class

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/088 (20130101)

Wireless Communication Networks
H04W 12/03 (20210101)
H04W 12/037 (20210101)
H04W 12/041 (20210101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11178166 Al Faruque et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Mohammad Abdullah Al Faruque (Irvine, California);  Jiang Wan (Irvine, California);  Sujit Rokka Chhetri (Irvine, California);  Sina Faezi (Irvine, California)
ABSTRACT A methodology as described herein allows cyber-domain tools such as computer aided-manufacturing (CAM) to be aware of the existing information leakage. Then, either machine process or product design parameters in the cyber-domain are changed to minimize the information leakage. This methodology aids the existing cyber-domain and physical-domain security solution by utilizing the cross-domain relationship.
FILED Friday, March 29, 2019
APPL NO 16/369993
ART UNIT 2434 — Cryptography and Security
CURRENT CPC
Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 50/02 (20141201)
B33Y 99/00 (20141201)

Electric Digital Data Processing
G06F 21/10 (20130101)
G06F 21/554 (20130101)
G06F 21/608 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/1433 (20130101) Original (OR) Class
H04L 63/1466 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11178349 Sankaranarayanan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) William Marsh Rice University (Houston, Texas)
ASSIGNEE(S) William Marsh Rice University (Houston, Texas)
INVENTOR(S) Aswin Sankaranarayanan (Houston, Texas);  Ashok Veeraraghavan (Houston, Texas);  Lisa A. Hendricks (Houston, Texas);  Richard Baraniuk (Houston, Texas);  Ali Ayremlou (Houston, Texas);  M. Salman Asif (Houston, Texas)
ABSTRACT A lens-free imaging system for generating an image of a scene includes an electromagnetic (EM) radiation sensor; a mask disposed between the EM radiation sensor and the scene; an image processor that obtains signals from the EM radiation sensor while the EM radiation sensor is exposed to the scene; and estimates the image of the scene based on, at least in part, the signals and a transfer function between the scene and the EM radiation sensor.
FILED Friday, January 29, 2016
APPL NO 15/547235
ART UNIT 2698 — Selective Visual Display Systems
CURRENT CPC
Measurement of Nuclear or X-radiation
G01T 1/295 (20130101)

Optical Elements, Systems, or Apparatus
G02B 27/42 (20130101)
G02B 2207/129 (20130101)

Pictorial Communication, e.g Television
H04N 5/30 (20130101)
H04N 5/225 (20130101)
H04N 5/378 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 11173426 Baxter et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Sustainable Energy Solutions, Inc. (Provo, Utah)
ASSIGNEE(S) Sustainable Energy Solutions, Inc. (Ball Ground, Georgia)
INVENTOR(S) Larry Baxter (Orem, Utah);  David Frankman (Provo, Utah);  Skyler Chamberlain (Provo, Utah);  Nathan Davis (Bountiful, Utah)
ABSTRACT Devices, systems, and methods are disclosed to separate solids from liquids. A vessel includes a screw, an inlet, a first outlet, and a second outlet. The inlet receives a first slurry having an incoming solids concentration. The first slurry consists of solids and a contact liquid. The first outlet is disposed toward the first end of the vessel. The second outlet is disposed toward a second end of the vessel. The screw preferentially conveys the solids over the contact liquid towards the second end of the vessel, the solids displacing at least a portion of the contact liquid, causing that portion of the contact liquid to flow toward the first outlet. A melting device is included.
FILED Friday, December 22, 2017
APPL NO 15/852801
ART UNIT 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 17/0214 (20130101)
B01D 21/009 (20130101)
B01D 21/2461 (20130101) Original (OR) Class

Refrigerators; Cold Rooms; Ice-boxes; Cooling or Freezing Apparatus Not Otherwise Provided for
F25D 3/10 (20130101)
F25D 3/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173461 Ye et al.
FUNDED BY
Department of Energy (DOE)
Lawrence Livermore National Laboratory (LLNL)
Lawrence Livermore National Security LLC (LLNS)
APPLICANT(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California);  PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California);  Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Congwang Ye (Livermore, California);  Roger D. Aines (Livermore, California);  Sarah E. Baker (Dublin, California);  Caitlyn Christian Cook (Livermore, California);  Eric B. Duoss (Dublin, California);  Joshua D. Kuntz (Livermore, California);  Elaine Lee (Brooklyn, New York);  James S. Oakdale (Castro Valley, California);  Andrew J. Pascall (Livermore, California);  Joshuah K. Stolaroff (Oakland, California);  Marcus A. Worsley (Hayward, California);  Carlos J. Martinez (West Lafayette, Indiana)
ABSTRACT Fabrication of functional polymer-based particles by crosslinking UV-curable polymer drops in mid-air and collecting crosslinked particles in a solid container, a liquid suspension, or an air flow. The particles can contain different phases in the form or layered structures that contain one to multiple cores, or structures that are blended with dissolved or emulsified smaller domains. A curing system produces ultraviolet rays that are directed onto the particles in the jet stream from one side. A reflector positioned on other side of the jet stream reflects the ultraviolet rays back onto the particles in the jet stream.
FILED Thursday, March 22, 2018
APPL NO 15/928522
ART UNIT 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 2/04 (20130101) Original (OR) Class
B01J 13/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173470 Tan et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYTEM (Austin, Texas)
ASSIGNEE(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Kui Tan (Plano, Texas);  Yves J. Chabal (Richardson, Texas)
ABSTRACT In some aspects, the present disclosure provides compositions comprising a nanoporous material such as a metal organic framework and an amine containing compound. In some aspects, these compositions may be used to improve the affinity of a guest molecule to the nanoporous material relative a nanoporous material which had not been treated with the amine containing compound.
FILED Tuesday, October 10, 2017
APPL NO 15/729350
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 53/02 (20130101)
B01D 2253/204 (20130101)
B01D 2253/308 (20130101)
B01D 2257/302 (20130101)
B01D 2257/404 (20130101)
B01D 2257/502 (20130101)
B01D 2257/504 (20130101)
B01D 2257/7022 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/223 (20130101) Original (OR) Class
B01J 20/2808 (20130101)
B01J 20/3425 (20130101)
B01J 20/3491 (20130101)
B01J 31/0209 (20130101)
B01J 31/0237 (20130101)
B01J 2220/46 (20130101)
B01J 2531/004 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 3/56 (20130101)

Acyclic or Carbocyclic Compounds
C07C 7/13 (20130101)
C07C 7/13 (20130101)
C07C 7/13 (20130101)
C07C 11/04 (20130101)
C07C 11/24 (20130101)
C07C 51/418 (20130101)

Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG]
Y02C 20/40 (20200801)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 20/50 (20151101)
Y02P 20/52 (20151101)
Y02P 20/151 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11173545 Qi et al.
FUNDED BY
Department of Energy (DOE)
Lawrence Livermore National Laboratory (LLNL)
Lawrence Livermore National Security LLC (LLNS)
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Zhen Qi (Tracy, California);  Juergen Biener (San Leandro, California);  Wen Chen (Livermore, California);  Eric Duoss (Dublin, California);  Christopher Spadaccini (Oakland, California);  Marcus A. Worsley (Hayward, California);  Jianchao Ye (Tracy, California);  Cheng Zhu (Livermore, California)
ABSTRACT The present disclosure relates to a method for forming a three dimensional, hierarchical, porous metal structure with deterministically controlled 3D multiscale pore architectures. The method may involve providing a feedstock able to be applied in an additive manufacturing process, and using an additive manufacturing process to produce a three dimensional (3D) structure using the feedstock. The method may involve further processing the 3D structure through at least a de-alloying operation to form a metallic 3D structure having an engineered, digitally controlled macropore morphology with integrated nanoporosity.
FILED Monday, October 23, 2017
APPL NO 15/790810
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 3/1115 (20130101)
B22F 3/1121 (20130101)
B22F 3/1146 (20130101) Original (OR) Class
B22F 10/10 (20210101)
B22F 10/20 (20210101)
B22F 10/38 (20210101)
B22F 10/62 (20210101)
B22F 2003/244 (20130101)
B22F 2003/248 (20130101)
B22F 2301/255 (20130101)
B22F 2998/10 (20130101)
B22F 2998/10 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 40/00 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174203 de Diego et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FE)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Peter de Diego (Zirconia, North Carolina);  John Ellington Greene (Greenville, South Carolina);  David Randall Hobart (Cincinnati, Ohio);  James Joseph Murray, III (Mauldin, South Carolina)
ABSTRACT A method of manufacturing a ceramic matrix composite (CMC) turbine nozzle shell is provided. The method includes: assembling a primary outer nozzle platform, a primary inner nozzle platform, a core and trailing edge preform, and an airfoil-shaped body; joining the primary outer nozzle platform to a secondary outer nozzle platform of the airfoil-shaped body; and joining the primary inner nozzle platform to a secondary inner nozzle platform of the airfoil-shaped body. Composite plies circumferentially surround the airfoil-shaped body, and their longitudinal edges are cut into fingers that are folded down. The fingers are interleaved between secondary platform plies to form the secondary outer and inner nozzle platforms.
FILED Thursday, October 25, 2018
APPL NO 16/170773
ART UNIT 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/80 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174276 Zhu et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
Alliance for Sustainable Energy, LLC (ASE)
National Renewable Energy Laboratory (NREL)
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) Kai Zhu (Littleton, Colorado);  Mengjin Yang (Dallas, Texas);  Donghoe Kim (Superior, Colorado)
ABSTRACT The present disclosure relates to a method that includes treating a liquid that includes a first precursor at a concentration C1, a second precursor at a concentration C2, a third precursor at a concentration C3, and an additive at a concentration C4, where the treating results in a perovskite, each of C1, C2, and C3 are between 0.001 M and 100 M, inclusively, and at least one of C4/C1 or C4/C2 equals a ratio greater than or equal to zero
FILED Wednesday, September 05, 2018
APPL NO 16/640903
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 7/24 (20130101) Original (OR) Class

Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 9/2059 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 51/0003 (20130101)
H01L 51/42 (20130101)
H01L 51/0077 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174277 Zhu et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
Alliance for Sustainable Energy, LLC (ASE)
National Renewable Energy Laboratory (NREL)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  Board of Trustees of Northern Illinois University (DeKalb, Illinois)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) Kai Zhu (Littleton, Colorado);  Tao Xu (Naperville, Illinois)
ABSTRACT The present disclosure relates to a composition that includes a sequestering material capable of binding a target material, where the sequestering material includes a first component that includes at least one of a functional group, a molecule, an oligomer, or a polymer, and the target material includes at least one of an element, a chemical, and/or a compound. In some embodiments of the present disclosure, the element may include at least one element from at least one of Rows 4, 5, 6, and 7 of the Periodic Table and/or an inner transition metal.
FILED Wednesday, January 08, 2020
APPL NO 16/736958
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/3873 (20130101)
C07F 9/4006 (20130101) Original (OR) Class

Compositions of Macromolecular Compounds
C08L 71/02 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/042 (20130101)

Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules
H02S 40/38 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174343 Rorrer et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
Alliance for Sustainable Energy, LLC (ASE)
National Renewable Energy Laboratory (NREL)
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) Nicholas Rorrer (Golden, Colorado);  Gregg Tyler Beckham (Golden, Colorado);  Caroline Bradshaw Hoyt (Denver, Colorado);  Jared Jon Anderson (Minneapolis, Minnesota)
ABSTRACT The present disclosure relates to a composition that includes
where A includes at least one of a carbon-carbon bond or a bridging group, R includes between 0 and 4 of a first hydrocarbon, and n is between 2 and 3,000. In some embodiments of the present disclosure, the bridging group may include a linear hydrocarbon chain and/or a branched hydrocarbon chain. In some embodiments of the present disclosure, the bridging group may include between 1 and 10 carbon atoms.
FILED Friday, February 14, 2020
APPL NO 16/791873
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 69/017 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 63/00 (20130101)
C08G 63/66 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174467 Malik et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Yield10 Bioscience, Inc. (Woburn, Massachusetts)
ASSIGNEE(S) YIELD10 BIOSCIENCE, INC. (Woburn, Massachusetts)
INVENTOR(S) Meghna Malik (Saskatoon, Canada);  Jihong Tang (West Roxbury, Massachusetts);  Kristi D. Snell (Belmont, Massachusetts)
ABSTRACT Transgenic plants having enhanced yield and having enhanced seed yield are disclosed. The transgenic plants are transformed with a transgenic polynucleotide encoding one or more metabolic enzymes. The metabolic enzymes can be from any biological source. The transgenic polynucleotide(s) comprises a nucleic acid sequences encoding the metabolic enzymes under the control of functional plant promoters, the one or more metabolic enzymes are targeted to the plastids by the addition of plastid targeting signals. Optionally the functional plant promoters are seed specific promoters and the metabolic enzymes are targeted to the plastids by the addition of plastid targeting peptide heterologous to the metabolic enzymes. Methods of making the transgenic plants and transgenic polynucleotides are disclosed. The magnitude of the increases in seed yield achieved with these transgenic plants are simply unprecedented.
FILED Friday, April 08, 2016
APPL NO 15/565086
ART UNIT 1663 — Plants
CURRENT CPC
Peptides
C07K 14/415 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/0006 (20130101) Original (OR) Class
C12N 15/52 (20130101)
C12N 15/8243 (20130101)
C12N 15/8247 (20130101)
C12N 15/8261 (20130101)

Enzymes
C12Y 101/01082 (20130101)

Technologies for Adaptation to Climate Change
Y02A 40/146 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174536 Tripathy
FUNDED BY
Department of Energy (DOE)
Battelle Energy Alliance, LLC (BEA)
APPLICANT(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S) Prabhat K. Tripathy (Idaho Falls, Idaho)
ABSTRACT A material (e.g., an alloy) comprises molybdenum, rhenium, and at least one element selected from the group consisting of tellurium, iodine, selenium, chromium, nickel, copper, titanium, zirconium, tungsten, vanadium, and niobium. Methods of forming the material (e.g., the alloy) comprise mixing molybdenum powder, rhenium powder, and a powder comprising at least one element selected from the group consisting of tellurium, iodine, selenium, chromium, nickel, copper, titanium, zirconium, tungsten, vanadium, and niobium. The mixed powders may be coalesced to form the material (e.g., the alloy).
FILED Tuesday, July 23, 2019
APPL NO 16/520117
ART UNIT 1796 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Alloys
C22C 1/045 (20130101)
C22C 27/04 (20130101) Original (OR) Class

Nuclear Reactors
G21C 3/07 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174570 Bidhar
FUNDED BY
Department of Energy (DOE)
Fermi National Accelerator Laboratory (FNAL)
Fermi Research Alliance, LLC (FRA)
APPLICANT(S) Fermi Research Alliance, LLC (Batavia, Illinois)
ASSIGNEE(S) Fermi Research Alliance, LLC (Batavia, Illinois)
INVENTOR(S) Sujit Bidhar (Carol Stream, Illinois)
ABSTRACT An electrospinning system, method, and apparatus comprises a dual polarity high voltage power supply with much less power out for safe operation, a solution dispensing assembly held at high positive potential by the dual polarity power supply, a Corona discharge assembly held at high negative potential by the dual polarity power supply, and a drum collector held at ground potential wherein a solution is drawn from the solution dispensing assembly to the drum collector thereby forming a fiber mat.
FILED Monday, February 04, 2019
APPL NO 16/266569
ART UNIT 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons
D01D 5/0038 (20130101)
D01D 5/0061 (20130101)
D01D 5/0069 (20130101)
D01D 5/0076 (20130101)
D01D 5/0084 (20130101) Original (OR) Class
D01D 5/0092 (20130101)
D01D 10/00 (20130101)

Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments
D01F 1/09 (20130101)
D01F 6/94 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174976 Symington et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOEOS)
APPLICANT(S) ULC ROBOTICS, INC. (Hauppauge, New York)
ASSIGNEE(S) ULC Robotics, Inc. (Hauppauge, New York)
INVENTOR(S) Alex Symington (Middle Island, New York);  David Meck (Patchogue, New York);  Aalap Rajendra Shah (Westbury, New York)
ABSTRACT A magnetic patch system includes a sealing member configured for attachment to a pipeline proximate to a breach in a wall of the pipeline. A magnet is positioned at least partially within a housing arrangement. The magnet may be oriented to generate a force toward the wall of the pipeline to attach the housing arrangement to the wall of the pipeline and capture the sealing member between the housing arrangement and the wall of the pipeline. The system may be installed inside a pipeline using a remotely controlled robotic system.
FILED Thursday, February 27, 2020
APPL NO 16/802906
ART UNIT 3753 — Fluid Handling and Dispensing
CURRENT CPC
Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General
F16L 55/18 (20130101)
F16L 55/162 (20130101) Original (OR) Class
F16L 55/1683 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11175417 Rice et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
National Technology and Engineering Solutions of Sandia, LLC (NTESS)
Sandia National Laboratories (SNL)
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) William Charles Rice (Torrance, California);  Matthew Jordan (Albuquerque, New Mexico);  James Ewers Levy (Albuquerque, New Mexico);  David P. Adams (Albuquerque, New Mexico);  Douglas R. Nichols (Albuquerque, New Mexico);  Richard Karl Harrison (Albuquerque, New Mexico);  Liam D. Claus (Albuquerque, New Mexico);  Daniel J. Dorsey (Sandia Park, New Mexico)
ABSTRACT A neutron detector including a plurality of layers of converter material and a plurality of layers of detector material. Each layer of converter material can be immediately adjacent to at least one layer of detector material and each layer of detector material can be immediately adjacent to at least one layer of converter material. The neutron detector may further include a read out integrated circuit (ROIC) that is electrically coupled to the plurality of layers of detector material. A value output by the ROIC may be indicative of a neutron interacting with a layer of converter material from amongst the plurality of layers of converter material.
FILED Monday, September 30, 2019
APPL NO 16/587580
ART UNIT 2884 — Optics
CURRENT CPC
Measurement of Nuclear or X-radiation
G01T 3/06 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11177047 van Rooyen et al.
FUNDED BY
Department of Energy (DOE)
Battelle Energy Alliance, LLC (BEA)
APPLICANT(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S) Isabella J. van Rooyen (Idaho Falls, Idaho);  Sean R. Morrell (Pocatello, Idaho)
ABSTRACT A method of forming one or more structures by additive manufacturing comprises introducing a first layer of a powder mixture comprising graphite and a fuel on a surface of a substrate. The first layer is at least partially compacted and then exposed to laser radiation to form a first layer of material comprising the fuel dispersed within a graphite matrix material. At least a second layer of the powder mixture is provided over the first layer of material and exposed to laser radiation to form inter-granular bonds between the second layer and the first layer. Related structures and methods of forming one or more structures are also disclosed.
FILED Tuesday, February 25, 2020
APPL NO 16/801011
ART UNIT 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 10/20 (20210101)
B22F 10/28 (20210101)

Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster
B28B 1/001 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/153 (20170801)
B29C 64/268 (20170801)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 70/00 (20141201)
B33Y 80/00 (20141201)

Nuclear Reactors
G21C 3/16 (20130101)
G21C 3/044 (20130101)
G21C 3/62 (20130101)
G21C 3/623 (20130101)
G21C 3/626 (20130101)
G21C 21/02 (20130101) Original (OR) Class

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 30/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11177055 Burkes
FUNDED BY
Department of Energy (DOE)
Savannah River Nuclear Solutions, LLC (SRNS)
APPLICANT(S) Savannah River Nuclear Solutions, LLC (Aiken, South Carolina)
ASSIGNEE(S) Savannah River Nuclear Solutions, LLC (Aiken, South Carolina)
INVENTOR(S) Klaehn W. Burkes (Wagener, South Carolina)
ABSTRACT A system for detecting water trees in branching underground electrical cables includes a pulse generator configured to inject a pulse into a first underground cable that branches into a second underground cable and a third underground cable. The system includes a first sensor associated with the first cable, a second sensor associated with the second cable, and a third sensor associated with the third cable. The system includes a control device configured to obtain a first, second, and third signal associated with the first, second and third sensors, respectively. The control device determines a lead-lag relationship between the second and third signals and determines presence of a water tree within at least one of the second and third cable based on the lead-lag relationship. When presence of a water tree is determined, the control device generates a control action associated with repairing or replacing the second and/or third cable.
FILED Friday, March 02, 2018
APPL NO 15/910407
ART UNIT 2867 — Printing/Measuring and Testing
CURRENT CPC
Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 7/32 (20130101)
H01B 7/2813 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11177126 Monavarian et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) STC.UNM (Albuquerque, New Mexico)
ASSIGNEE(S)
INVENTOR(S) Morteza Monavarian (Albuquerque, New Mexico);  Daniel Feezell (Albuquerque, New Mexico);  Andrew Aragon (Albuquerque, New Mexico);  Saadat Mishkat-Ul-Masabih (Albuquerque, New Mexico);  Andrew Allerman (Tijeras, New Mexico);  Andrew Armstrong (Albuquerque, New Mexico);  Mary Crawford (Albuquerque, New Mexico)
ABSTRACT A method comprises providing a substrate comprising an n-type Al/In/GaN semiconductor material. A surface of the substrate is dry-etched to form a trench therein and cause dry-etch damage to remain on the surface. The surface of the substrate is immersed in an electrolyte solution and illuminated with above bandgap light having a wavelength that generates electron-hole pairs in the n-type Al/In/GaN semiconductor material, thereby photoelectrochemically etching the surface to remove at least a portion of the dry-etch damage.
FILED Thursday, November 14, 2019
APPL NO 16/684313
ART UNIT 2816 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/0254 (20130101)
H01L 21/02057 (20130101) Original (OR) Class
H01L 21/02389 (20130101)
H01L 21/02433 (20130101)
H01L 21/3065 (20130101)
H01L 21/30612 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11177396 Wheeler
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
Alliance for Sustainable Energy, LLC (ASE)
National Renewable Energy Laboratory (NREL)
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) Lance Michael Wheeler (Golden, Colorado)
ABSTRACT The present disclosure relates to a device that includes a perovskite layer, a first charge-transport layer, and an adhesion layer, where the adhesion layer is positioned between the charge transport layer and the perovskite layer, the adhesion layer forms a first bond with the charge transport layer, and the adhesion layer forms a second bond with the perovskite layer.
FILED Sunday, December 23, 2018
APPL NO 16/231571
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/15 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/048 (20130101)
H01L 31/02008 (20130101)
H01L 31/02021 (20130101) Original (OR) Class
H01L 51/0037 (20130101)
H01L 51/44 (20130101)
H01L 51/424 (20130101)
H01L 51/4246 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11177402 Ptak et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
Alliance for Sustainable Energy, LLC (ASE)
National Renewable Energy Laboratory (NREL)
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) Aaron Joseph Ptak (Littleton, Colorado);  Kevin Louis Schulte (Denver, Colorado);  John David Simon (Austin, Texas)
ABSTRACT The present disclosure relates to a method that includes contacting a surface of a first layer that includes a Group III element and a Group V element with a gas that includes HCl, where the first layer is positioned in thermal contact with a wafer positioned in a chamber of a reactor, and the contacting results in a roughening of the surface.
FILED Tuesday, September 10, 2019
APPL NO 16/565827
ART UNIT 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/186 (20130101)
H01L 31/0445 (20141201)
H01L 31/0547 (20141201)
H01L 31/0735 (20130101)
H01L 31/1844 (20130101)
H01L 31/02363 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11177439 Bailie et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Tandem PV, Inc. (Palo Alto, California)
ASSIGNEE(S) Tandem PV, Inc. (Palo Alto, California)
INVENTOR(S) Colin David Bailie (Morgan Hill, California);  Chris Eberspacher (Palo Alto, California);  Matthew Cornyn Kuchta (San Francisco, California)
ABSTRACT A method can comprise providing an ink comprising reactants, a complexing agent, and a solvent, depositing the ink onto a substrate to form a wet film, drying the wet film to form a precursor layer, and annealing the precursor layer to form a perovskite film. The reactants can comprise a first and a second cation, a first metal, and a first and a second anion, wherein the first and second cations are different from each other, and the first and second anions are different from each other. The complexing agent can comprise a heterocyclic donor material. The perovskite film can comprise a mixed-cation mixed-halide perovskite material, and less than 5% by mass of the complexing agent. The perovskite film can also be formed using a one-step process.
FILED Tuesday, March 03, 2020
APPL NO 16/808175
ART UNIT 2819 — Semiconductors/Memory
CURRENT CPC
Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 9/2059 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/18 (20130101)
H01L 51/0004 (20130101) Original (OR) Class
H01L 51/0026 (20130101)
H01L 51/42 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11177497 Sankarasubramanian et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Shrihari Sankarasubramanian (St. Louis, Missouri);  Vijay K. Ramani (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Shrihari Sankarasubramanian (St. Louis, Missouri);  Vijay K. Ramani (St. Louis, Missouri)
ABSTRACT Disclosed herein is a redox flow battery (RFB). The battery generally includes: a positive electrolyte that is a first metal ion, a negative electrolyte that is a second metal ion, an ion exchange membrane positioned between the positive electrolyte and the negative electrolyte. The membrane is configured to restrict and/or prevent the passage of the first metal ion and/or the second metal ion therethrough, and is configured to maintain ionic conductivity between the positive electrolyte and the negative electrolyte.
FILED Tuesday, March 12, 2019
APPL NO 16/299693
ART UNIT 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 8/083 (20130101)
H01M 8/188 (20130101) Original (OR) Class
H01M 8/0482 (20130101)
H01M 8/1004 (20130101)
H01M 2300/0011 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11177626 Patra et al.
FUNDED BY
Department of Energy (DOE)
Lawrence Livermore National Laboratory (LLNL)
Lawrence Livermore National Security LLC (LLNS)
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Liveremore National Security, LLC (Livermore, California)
INVENTOR(S) Susant Patra (Brentwood, California);  Robert J. Deri (Pleasanton, California);  John W. Elmer (Danville, California)
ABSTRACT A pyrolytic graphite (PG) substrate and laser diode package includes a substrate body having a PG crystalline structure with a basal plane oriented at a pre-determined orientation angle as measured from a longitudinal axis of a heat generating material, such as a laser diode, mounted on a surface of the PG substrate, so that a coefficient of thermal expansion (CTE) of the PG substrate is substantially matched with a CTE of the material.
FILED Thursday, March 24, 2016
APPL NO 15/080516
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 23/5226 (20130101)
H01L 23/53228 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 5/021 (20130101)
H01S 5/024 (20130101)
H01S 5/0206 (20130101)
H01S 5/02423 (20130101)
H01S 5/02469 (20130101) Original (OR) Class
H01S 5/4025 (20130101)
H01S 5/32316 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11177890 Soh et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
National Technology and Engineering Solutions of Sandia, LLC (NTESS)
Sandia National Laboratories (SNL)
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Daniel Beom Soo Soh (Pleasanton, California);  Matt Eichenfield (Albuquerque, New Mexico)
ABSTRACT A quantum communication system includes a first quantum transceiver, a second quantum transceiver, and a quantum communication mediator (QCM) system. The transceivers have different resonant frequencies or physical systems. The QCM system receives an initial quantum signal from the first quantum transceiver. The QCM system transfers a quantum state of the initial quantum signal to a first mechanical signal and then from the first mechanical signal to a first pair of optical signals by way of a first three-wave mixing process. The QCM transfers the quantum state to a second pair of optical signals from the first pair by way of a four-wave mixing process. The QCM transfers the quantum state from the second pair of optical signals to a second mechanical signal by way of a second three-wave mixing process. The QCM transfers the quantum state from the second mechanical signal to a final quantum signal by mechanical transduction.
FILED Thursday, December 03, 2020
APPL NO 17/110477
ART UNIT 2636 — Optical Communications
CURRENT CPC
Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement
G01P 15/093 (20130101)

Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101)

Transmission
H04B 10/70 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11178176 McCann et al.
FUNDED BY
Department of Energy (DOE)
Office of Electricity (DOE-OE)
APPLICANT(S) BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas)
ASSIGNEE(S) BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas)
INVENTOR(S) Roy McCann (Fayetteville, Arkansas);  Hamdi Mansour Albunashee (Fayetteville, Arkansas)
ABSTRACT A system for detecting MITM for SCADA communication networks includes secure substation-substation communication links for providing secure and reliable paths to exchange OT data between substations for OT data consistency check; a SIB in each substation for sampling CT and PT measurements to calculate voltage magnitude and phase angle thereof; a S&C server in each substation coupled to the SIB for receiving the voltage magnitude and phase angle from the SIB and obtaining a packet carrying active power flow in transmission lines between two substations and a time stamp; an IDS server placed in a SCADA center for collecting the packet of each substation sent by the S&C server; analyzing the received packet from every adjacent substation; inspecting the payload of the received packet; and triggering an intrusion alarm to a SCADA operator when the power flow is not the same as the payload of the packets.
FILED Tuesday, March 24, 2020
APPL NO 16/828006
ART UNIT 2493 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 43/106 (20130101)
H04L 63/1425 (20130101)
H04L 63/1466 (20130101) Original (OR) Class
H04L 69/22 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 11174816 Banham et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Rolls-Royce Corporation (Indianapolis, Indiana)
ASSIGNEE(S) Rolls-Royce Corporation (Indianapolis, Indiana)
INVENTOR(S) Christopher Banham (Indianapolis, Indiana);  Rex M. Little (Indianapolis, Indiana)
ABSTRACT A gas turbine engine coupled to an aircraft includes an engine core arranged axially along an axis, a bypass duct arranged circumferentially around the engine core to define a bypass channel, and a heat exchanger system. The bypass channel is arranged to conduct bypass air around the engine core to provide thrust for the gas turbine engine. The heat exchanger system is configured to provide cooling for the engine core.
FILED Monday, February 25, 2019
APPL NO 16/284597
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 33/08 (20130101)
B64D 2033/024 (20130101)
B64D 2033/0286 (20130101)

Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 7/18 (20130101)

Jet-propulsion Plants
F02K 3/06 (20130101) Original (OR) Class
F02K 3/025 (20130101)
F02K 3/115 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2260/213 (20130101)
F05D 2260/232 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174850 Benafan et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Glenn Research Center (GLENN)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Othmane Benafan (Middleburg Heights, Ohio);  Phillip B. Abel (Cleveland, Ohio);  Steven W. Bauman (Cleveland, Ohio);  Darrell J. Gaydosh (Cleveland, Ohio);  Paul A. Solano (Cleveland, Ohio)
ABSTRACT A plurality of shape memory alloy tubes (SMTs) of one or more shape memory alloy (SMA) types is configured as an element in a rotary actuator system in a nested manner. In various configurations, the nested SMTs provide one or more modes of multiplication (torque output or angular displacement), rotation reversibility and bias loading. The innovation provides for leveraging the modes for reductions in the rotary actuator system size, weight, or complexity or combinations thereof, or providing improved and more stable actuation capabilities in a given envelope.
FILED Friday, January 24, 2020
APPL NO 16/751749
ART UNIT 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for
F03G 7/065 (20130101) Original (OR) Class

Gearing
F16H 35/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11175232 Abedin et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
INVENTOR(S) M. Nural Abedin (Yorktown, Virginia);  Arthur T. Bradley (Yorktown, Virginia);  Anupam Kumar Misra (Honolulu, Hawaii);  Yingxin Bai (Yorktown, Virginia)
ABSTRACT Standoff ultra-compact micro-Raman sensors configured to receive Raman scattering from a substance are disclosed. A laser device may be configured to transmit a laser at a first wavelength. The laser may be expanded to a predetermined size, focused through a lens, and made incident on an unknown substance. A filter may reflect the laser and Rayleigh scattering from the substance, but may permit Raman scattering and laser-induced fluorescence from the substance. One or more lenses and/or filters may receive and pass the Raman scattering and/or laser-induced fluorescence to a light sensor. The received Raman scattering and/or laser-induced fluorescence may be compared to known fingerprints of substances to determine an identity of the substance. The wavelength of the laser, the width of the laser, and other parameters may be varied based on the distance between the standoff ultra-compact micro-Raman sensor and the substance.
FILED Wednesday, December 19, 2018
APPL NO 16/225786
ART UNIT 2886 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/65 (20130101) Original (OR) Class
G01N 21/6402 (20130101)
G01N 21/6458 (20130101)
G01N 2201/0221 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11177512 Chou et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Jet Propulsion Laboratory (JPL)
APPLICANT(S) HONDA MOTOR CO., LTD. (Tokyo, Japan);  CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) HONDA MOTOR CO., LTD. (Tokyo, Japan);  CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Nam Hawn Chou (Dublin, Ohio);  Kaoru Omichi (Columbus, Ohio);  Ryan McKenney (Upper Arlington, Ohio);  Qingmin Xu (Columbus, Ohio);  Christopher Brooks (Dublin, Ohio);  Simon C. Jones (Azusa, California);  Isabelle M. Darolles (Azusa, California);  Hongjin Tan (Pasadena, California)
ABSTRACT The present disclosure relates to a method of making core-shell and yolk-shell nanoparticles, and to electrodes comprising the same. The core-shell and yolk-shell nanoparticles and electrodes comprising them are suitable for use in electrochemical cells, such as fluoride shuttle batteries. The shell may protect the metal core from oxidation, including in an electrochemical cell. In some embodiments, an electrochemically active structure includes a dimensionally changeable active material forming a particle that expands or contracts upon reaction with or release of fluoride ions. One or more particles are at least partially surrounded with a fluoride-conducting encapsulant and optionally one or more voids are formed between the active material and the encapsulant using sacrificial layers or selective etching. The fluoride-conducting encapsulant may comprise one or more metals. When the electrochemically active structures are used in secondary batteries, the presence of voids can accommodate dimensional changes of the active material.
FILED Wednesday, June 20, 2018
APPL NO 16/013739
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals
C01F 11/22 (20130101)
C01F 17/30 (20200101)
C01F 17/265 (20200101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/54 (20130101)
C01P 2002/72 (20130101)
C01P 2002/85 (20130101)
C01P 2004/03 (20130101)
C01P 2004/04 (20130101)
C01P 2004/80 (20130101)
C01P 2006/40 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/38 (20130101)
H01M 4/136 (20130101)
H01M 4/366 (20130101)
H01M 10/36 (20130101) Original (OR) Class
H01M 10/054 (20130101)
H01M 2300/0034 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 11175224 Douglass et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland)
ASSIGNEE(S) GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland)
INVENTOR(S) Kevin O'Connell Douglass (Ellicott City, Maryland);  Stephen Paul Eckel (Gaithersburg, Maryland);  Jacob Edmond Ricker (Gaithersburg, Maryland);  Jay Howard Hendricks (Clarksburg, Maryland)
ABSTRACT An optical refraction barometer measures pressure based on refractivity changes and includes: an optical light source; an optical frequency controller; a first optical phase controller; a first polarization controller; an electronic reference arm in optical communication with the first polarization controller; a second optical phase controller in optical communication with the optical frequency controller; a second polarization controller in optical communication with the second optical phase controller; an electronic sample arm in optical communication with the second polarization controller and in electrical communication with the second optical phase controller; a second sideband frequency generator; a mixer in electrical communication with the detector and the second sideband frequency generator; and a first sideband frequency generator in electrical communication with the mixer; and a dual fixed length optical cavity refractometer.
FILED Friday, July 24, 2020
APPL NO 16/938300
ART UNIT 2877 — Optics
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 9/02011 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/41 (20130101) Original (OR) Class
G01N 2021/4106 (20130101)
G01N 2021/4153 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11175826 Kuhn
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland)
ASSIGNEE(S) GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland)
INVENTOR(S) David Richard Kuhn (Columbia, Maryland)
ABSTRACT Provided is a process including: initializing a data block matrix; making supra-diagonal nodes that include at most one more node than sub-diagonal nodes; making a hash nodes with a hash sequence length that is proportional to a number of nodes in the row or column of nodes in which the hash node is arranged; and writing data blocks in nodes of the data block matrix such that a number of data blocks in nodes in the data block matrix is less than (N2−N) for N number of nodes in the data block matrix, wherein the data block matrix has dispersed data blocks.
FILED Wednesday, April 29, 2020
APPL NO 16/861309
ART UNIT 2138 — Memory Access and Control
CURRENT CPC
Electric Digital Data Processing
G06F 3/067 (20130101)
G06F 3/0604 (20130101) Original (OR) Class
G06F 3/0652 (20130101)
G06F 3/0659 (20130101)
G06F 21/6218 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 11173871 Eddy et al.
FUNDED BY
Department of Transportation (USDOT)
APPLICANT(S) The University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) THE UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts)
INVENTOR(S) Douglas Eddy (Amherst, Massachusetts);  Sundar Krishnamurty (Amherst, Massachusetts);  Shreyas Patil (Amherst, Massachusetts);  Anne Schewe (Amherst, Massachusetts)
ABSTRACT Disclosed is a retrofitting seatbelt system for a motor coach, the system including: a base plate, the base plate configured to connect to a floor rail of the motor coach; a longitudinal post configured to support a belt, the longitudinal post defines a longitudinal post inner end connected to the base plate, wherein the longitudinal post extends away from the base plate in a longitudinal direction to a longitudinal post outer end, wherein the longitudinal post defines a forward-side that faces a forward direction, and an aft-side that faces an aft direction, wherein the forward direction and the aft direction are disposed along a forward-aft axis; and a first motion damper connected to the longitudinal post near the longitudinal post outer end, the first motion damper extends in the aft direction, beyond the aft-side of the longitudinal post.
FILED Thursday, February 13, 2020
APPL NO 16/789842
ART UNIT 3616 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Vehicles, Vehicle Fittings, or Vehicle Parts, Not Otherwise Provided for
B60R 22/22 (20130101)
B60R 22/34 (20130101)
B60R 22/3413 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174214 Brown et al.
FUNDED BY
Department of Transportation (USDOT)
Federal Aviation Administration (FAA)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Moira Caitlin Brown (Chicago, Illinois);  Elizabeth Ganz Stubbs (Amherst, Massachusetts);  Todd Emrick (South Deerfield, Massachusetts)
ABSTRACT The invention provides novel deoxybenzoin-containing polymers exhibiting branched (including hyperbranched) architectures, and related methods and uses thereof.
FILED Friday, May 17, 2019
APPL NO 16/415081
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 51/347 (20130101)
C07C 65/40 (20130101) Original (OR) Class

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 63/06 (20130101)

Compositions of Macromolecular Compounds
C08L 67/04 (20130101)
C08L 2201/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 11173150 Finegold
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) United States Government As Represented By The Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) United States Government As Represented By The Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Sydney M. Finegold (Los Angeles, California)
ABSTRACT The invention provides for methods of treating autism associated with Desulfovibrio overgrowth in the gastrointestinal tract of a patient, said method comprising administering to the patient suffering from said autism a treatment course of aztreonam in an amount effective to treat autism in the patient, thereby treating autism.
FILED Friday, November 16, 2018
APPL NO 16/192880
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/43 (20130101)
A61K 31/43 (20130101)
A61K 31/397 (20130101)
A61K 31/397 (20130101)
A61K 31/424 (20130101)
A61K 31/424 (20130101)
A61K 31/427 (20130101) Original (OR) Class
A61K 31/427 (20130101)
A61K 31/431 (20130101)
A61K 31/431 (20130101)
A61K 35/741 (20130101)
A61K 35/745 (20130101)
A61K 35/747 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/18 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11174521 Finegold et al.
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Sydney M. Finegold (Los Angeles, California);  Paula Carlson (Los Angeles, California)
ABSTRACT The invention includes a method of diagnosis and treating autism associated with an overgrowth of beta2-toxin-gene-positive Clostridium perfringens in the gut of an autistic subject. In one embodiment, the method comprises administering to the subject (e.g. a subject having an overgrowth of beta2-toxin-gene-positive Clostridium perfringens in the gut) one or more agents to reduce or eliminate beta2-toxin-gene positive Clostridium perfringens in the subject so as to relieve one or more symptoms of autism.
FILED Friday, May 10, 2019
APPL NO 16/409334
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/689 (20130101) Original (OR) Class
C12Q 1/6883 (20130101)
C12Q 2600/106 (20130101)
C12Q 2600/118 (20130101)
C12Q 2600/158 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US PP33636 Lewers et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Kimberly S. Lewers (Columbia, Maryland);  John M. Enns (Hyattsville, Maryland)
ABSTRACT This invention relates to a new and distinct cultivar of strawberry named ‘Cordial’. The new late-season cultivar is primarily characterized by the uniformity and symmetry of fruit shape and size, evenness of color, glossiness of fruit skin, freshness and health of calyx, being free of physiologically-based blemishes such sun scald, bronzing, and rain damage and shelf life of the fruit.
FILED Monday, July 27, 2020
APPL NO 16/939591
ART UNIT 1661 — Plants
CURRENT CPC
Plants
PLT/208
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 11177631 Kurczveil et al.
FUNDED BY
National Security Agency (NSA)
Maryland Procurement Office (MPO)
APPLICANT(S) HEWLETT PACKARD ENTERPRISE DEVELOPMENT LP (Houston, Texas)
ASSIGNEE(S) Hewlett Packard Enterprise Development LP (Houston, Texas)
INVENTOR(S) Geza Kurczveil (Palo Alto, California);  Di Liang (Palo Alto, California);  Raymond G. Beausoleil (Palo Alto, California)
ABSTRACT Examples disclosed herein relate to multi-wavelength semiconductor comb lasers. In some examples disclosed herein, a multi-wavelength semiconductor comb laser may include a waveguide included in an upper silicon layer of a silicon-on-insulator (SOI) substrate. The comb laser may include a quantum dot (QD) active gain region above the SOI substrate defining an active section in a laser cavity of the comb laser and a dispersion tuning section included in the laser cavity to tune total cavity dispersion of the comb laser.
FILED Wednesday, May 13, 2020
APPL NO 15/930955
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/106 (20130101)
H01S 5/14 (20130101)
H01S 5/021 (20130101)
H01S 5/026 (20130101)
H01S 5/068 (20130101)
H01S 5/142 (20130101)
H01S 5/0651 (20130101)
H01S 5/1014 (20130101)
H01S 5/1032 (20130101) Original (OR) Class
H01S 5/1039 (20130101)
H01S 5/1071 (20130101)
H01S 5/1096 (20130101)
H01S 5/3412 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 11177400 Welser et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
Small Business Administration (SBA)
Small Business Technology Transfer (STTR)
APPLICANT(S) Magnolia Optical Technologies, Inc. (Woburn, Massachusetts)
ASSIGNEE(S) Magnolia Optical Technologies, Inc. (Woburn, Massachusetts)
INVENTOR(S) Roger E. Welser (Providence, Rhode Island);  Ashok K. Sood (Brookline, Massachusetts)
ABSTRACT Refractive optical element designs are provided for high geometric optical efficiency over a wide range of incident angles. To minimize Fresnel reflection losses, the refractive optical element designs employ multiple encapsulant materials, differing in refractive index. Concentrator photovoltaic subassemblies are formed by embedding a high efficiency photovoltaic device within the refractive optical element, along with appropriate electrical contacts and heat sinks. Increased solar electric power output is obtained by employing a single-junction III-V material structure with light-trapping structures.
FILED Monday, September 18, 2017
APPL NO 15/708057
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/0232 (20130101) Original (OR) Class
H01L 31/0543 (20141201)
H01L 31/0547 (20141201)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 11174757 Cerino et al.
FUNDED BY
APPLICANT(S) United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S) Raytheon Technologies Corporation (Farmington, Connecticut)
INVENTOR(S) Joseph N. Cerino (Middletown, Connecticut);  Andrew Yanaros (West Hartford, Connecticut);  Paul W. Duesler (Manchester, Connecticut)
ABSTRACT An assembly is provided for a turbine engine with an axial centerline. This assembly includes a turbine engine structure and a valve assembly. The turbine engine structure includes an outer duct wall, an inner duct wall, a first flow path and a second flow path. The inner duct wall is radially inward of the outer duct wall. The first flow path is radially inward of the inner duct wall. The second flow path is radially outward of the inner duct wall and is radially inward of the outer duct wall. The valve assembly includes a valve element and a valve actuator. The valve element is configured to regulate flow of fluid between the first flow path and the second flow path. The valve actuator is configured to move the valve element. The valve actuator is positioned entirely radially outward of the outer duct wall.
FILED Monday, January 20, 2020
APPL NO 16/747330
ART UNIT 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 17/105 (20130101)
F01D 25/24 (20130101) Original (OR) Class

Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 6/08 (20130101)
F02C 9/18 (20130101)
F02C 9/52 (20130101)

Non-positive-displacement Pumps
F04D 27/023 (20130101)
F04D 27/0215 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11175437 Starkovich et al.
FUNDED BY
APPLICANT(S) Northrop Grumman Systems Corporation (Falls Church, Virginia)
ASSIGNEE(S) NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia)
INVENTOR(S) John A. Starkovich (Redondo Beach, California);  Edward M. Silverman (Encino, California)
ABSTRACT A high-performance optical absorber includes: a texturized base layer, the base layer comprising one or more of a polymer film and a polymer coating; and a surface layer located above and immediately adjacent to the base layer, the surface layer joined to the base layer, the surface layer comprising a plasma-functionalized, non-woven carbon nanotube (CNT) sheet. A method using capillary force lamination (CFL) for manufacturing a high-performance optical absorber, includes: texturizing a base layer of the high-performance optical absorber, the base layer comprising one or more of a polymer film and a polymer coating; joining a surface layer of the high-performance optical absorber to the base layer, the surface layer comprising a non-woven carbon nanotube (CNT) sheet; wetting the joined surface layer and base layer with a solvent; drying the joined surface layer and base layer; and treating the resulting base layer with plasma, creating the high-performance optical absorber.
FILED Tuesday, December 29, 2020
APPL NO 17/136703
ART UNIT 2872 — Optics
CURRENT CPC
Producing Particular Articles From Plastics or From Substances in a Plastic State
B29D 11/0074 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 80/00 (20141201)

Optical Elements, Systems, or Apparatus
G02B 5/003 (20130101) Original (OR) Class
G02B 2207/101 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11177848 Zalucki et al.
FUNDED BY
APPLICANT(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
ASSIGNEE(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S) Michael A. Zalucki (Hollis, New Hampshire);  Tyler M. Hayslett (Nashua, New Hampshire)
ABSTRACT Techniques are provided for signal detection based on the Gibbs phenomenon. A methodology implementing the techniques according to an embodiment includes transforming an input signal to the frequency domain and performing median filtering of amplitudes associated with frequency bins of the frequency domain transformed input signal. The median filtering is performed to attenuate longer duration or continuous signal components that may be present in the input signal. The method also includes identifying a sinc function main lobe in the median filtered signal, the sinc function associated with the Gibbs phenomenon. The method further includes detecting a discontinuity in the input signal based on the identified sinc function main lobe. The discontinuity is associated with a shorter duration signal component that is present in the input signal. Shorter duration signal components may include relatively narrow signal pulses and relatively fast rising or falling signal edges.
FILED Friday, September 11, 2020
APPL NO 17/018299
ART UNIT 2637 — Optical Communications
CURRENT CPC
Electric Digital Data Processing
G06F 17/142 (20130101)

Transmission
H04B 1/16 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11177852 Zalucki
FUNDED BY
APPLICANT(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
ASSIGNEE(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S) Michael A. Zalucki (Hollis, New Hampshire)
ABSTRACT Techniques are provided for tracking of signals. A methodology implementing the techniques according to an embodiment includes filtering a first segment of an input signal, associated with a first time interval, into a first plurality of frequency bins. The method also includes detecting a signal of interest (SOI) in one of the first plurality of frequency bins. The method further includes filtering a second segment of the input signal, associated with a second time interval, into a second plurality of frequency bins. The method further includes determining movement of the SOI from a first frequency bin, of the first plurality of frequency bins, to a second frequency bin, of the second plurality of frequency bins. The method further includes tracking the SOI based on the movement determination. In some cases, the method further includes creating a composite signal based on the tracking over multiple frequency bins and multiple time intervals.
FILED Tuesday, September 22, 2020
APPL NO 17/027901
ART UNIT 2636 — Optical Communications
CURRENT CPC
Transmission
H04B 1/7102 (20130101) Original (OR) Class

Transmission of Digital Information, e.g Telegraphic Communication
H04L 2025/03522 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, November 16, 2021.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

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THE PANEL
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FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
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FILED
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APPL NO
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3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

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CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

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You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2021/details-patents-20210427.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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