FedInvent™ Patents
Patent Details for Tuesday, November 23, 2021
This page was updated on Wednesday, November 24, 2021 at 05:25 AM GMT
Department of Health and Human Services (HHS)
| US 11179047 | Mukkamala et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan); University of Maryland (College Park, Maryland) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Ramakrishna Mukkamala (Okemos, Michigan); Anand Chandrasekhar (East Lansing, Michigan); Jin-Oh Hahn (Rockville, Maryland) |
| ABSTRACT | A system and method is presented for cuff-less blood pressure measurement in a mobile device. A key aspect of this disclosure is the discovery of a new location for blood pressure measurement at the fingertip of a subject and that reflectance-mode photoplethysmography can be used to help make this measurement. Through experiments in human subjects, it was discovered that it is indeed possible to measure systemic blood pressure by having a subject press the fingertip against a reflectance-mode photo-plethysmography-force sensor unit under visual guidance and then compute blood pressure from the resulting variable-amplitude blood volume oscillations and applied pressure via an oscillometric algorithm. |
| FILED | Thursday, July 18, 2019 |
| APPL NO | 16/515590 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0077 (20130101) A61B 5/0261 (20130101) A61B 5/0295 (20130101) A61B 5/706 (20130101) A61B 5/743 (20130101) A61B 5/02055 (20130101) A61B 5/02141 (20130101) Original (OR) Class A61B 5/02225 (20130101) A61B 5/02416 (20130101) A61B 5/6898 (20130101) A61B 2560/0462 (20130101) A61B 2562/0238 (20130101) A61B 2562/0247 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11179050 | Liu et al. |
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| FUNDED BY |
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| APPLICANT(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan); UNIVERSITY OF MARYLAND (College Park, Maryland) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan); University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Jiankun Liu (East Lansing, Michigan); Mohsen Moslehpour (Sunnyvale, California); Jin-Oh Hahn (Rockville, Maryland); Ramakrishna Mukkamala (Okemos, Michigan) |
| ABSTRACT | Most automatic cuff blood pressure (BP) measurement devices are based on oscillometry. These devices estimate BP from the envelopes of the cuff pressure oscillations using fixed ratios. The values of the fixed ratios represent population averages, so the devices may be accurate only in subjects with normal BP levels. A patient-specific oscillometric BP measurement method was developed. The idea was to represent the cuff pressure oscillation envelopes with a physiologic model and then estimate the patient-specific parameters of the model, which includes BP levels, by optimally fitting it to the envelopes. |
| FILED | Friday, September 09, 2016 |
| APPL NO | 15/758401 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/02 (20130101) A61B 5/021 (20130101) A61B 5/022 (20130101) A61B 5/02225 (20130101) Original (OR) Class A61B 2562/0247 (20130101) Electric Digital Data Processing G06F 2111/10 (20200101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11179052 | Griswold et al. |
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| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Mark A. Griswold (Shaker Heights, Ohio); Anagha Deshmane (Cleveland Heights, Ohio); Jeffrey Sunshine (Pepper Pike, Ohio) |
| ABSTRACT | Example embodiments associated with characterizing a sample using NMR fingerprinting are described. One example NMR apparatus includes an NMR logic that repetitively and variably samples a (k, t, E) space associated with an object to acquire a set of NMR signals that are associated with different points in the (k, t, E) space. Sampling is performed with t and/or E varying in a non-constant way. The NMR apparatus may also include a signal logic that produces an NMR signal evolution from the NMR signals and a characterization logic that characterizes a tissue in the object as a result of comparing acquired signals to reference signals. Example embodiments facilitate distinguishing diseased tissue from healthy tissue based on tissue component fractions identified using the NMR fingerprinting. |
| FILED | Monday, October 15, 2018 |
| APPL NO | 16/159888 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/00 (20130101) A61B 5/055 (20130101) A61B 5/0263 (20130101) Original (OR) Class A61B 5/742 (20130101) A61B 5/4064 (20130101) A61B 17/00 (20130101) A61B 2217/00 (20130101) A61B 2218/00 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 1/00 (20130101) G01R 33/50 (20130101) G01R 33/448 (20130101) G01R 33/4818 (20130101) G01R 33/4828 (20130101) G01R 33/5602 (20130101) G01R 33/5608 (20130101) G01R 33/5611 (20130101) G01R 33/56366 (20130101) G01R 33/56563 (20130101) Image Data Processing or Generation, in General G06T 1/00 (20130101) G06T 2200/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11179156 | Rafiee et al. |
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| FUNDED BY |
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| APPLICANT(S) | Transmural (Andover, Massachusetts); The United States of America, as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary, Department of Health and Human Services (Bethseda, Maryland); Transmural Systems LLC (Andover, Massachusetts) |
| INVENTOR(S) | Nasser Rafiee (Andover, Massachusetts); Stuart MacDonald (Andover, Massachusetts); Robert J. Lederman (Chevy Chase, Maryland); Kanishka Ratnayaka (Bethesda, Maryland); Biwei MacDonald (Andover, Massachusetts); Alana Rafiee (Andover, Massachusetts) |
| ABSTRACT | In some implementations, a radially self-expanding endograft prosthesis is provided that includes (i) distal flange that is self-expanding and configured to flip generally perpendicularly with respect to a body of the prosthesis to help seat the prosthesis against a tissue wall, (ii) a distal segment extending proximally from the distal flange that has sufficient stiffness to maintain a puncture open that is formed through a vessel wall (iii) a compliant middle segment extending proximally from the distal segment, the middle segment being more compliant than the distal segment, and having independently movable undulating strut rings attached to a tubular fabric, the combined structure providing flexibility and compliance to allow for full patency while flexed, the segment being configured to accommodate up to a 90 degree bend, (iv) a proximal segment having a plurality of adjacent undulating strut rings that are connected to each other. |
| FILED | Tuesday, April 30, 2019 |
| APPL NO | 16/399670 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/11 (20130101) Original (OR) Class A61B 2017/00252 (20130101) A61B 2017/1107 (20130101) A61B 2017/1139 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/07 (20130101) A61F 2/064 (20130101) A61F 2002/828 (20130101) A61F 2002/91575 (20130101) A61F 2250/0029 (20130101) A61F 2250/0039 (20130101) A61F 2250/0082 (20130101) A61F 2250/0098 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11179341 | Traverso et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Carlo Giovanni Traverso (Newton, Massachusetts); Alex G. Abramson (St. Louis, Missouri); Ester Caffarel Salvador (Cambridge, Massachusetts); Niclas Roxhed (Cambridge, Massachusetts); Minsoo Khang (Boston, Massachusetts); Taylor Bensel (Walpole, Massachusetts); Robert S. Langer (Newton, Massachusetts) |
| ABSTRACT | Self-righting articles, such as self-righting capsules for administration to a subject, are generally provided. In some embodiments, the self-righting article may be configured such that the article may orient itself relative to a surface (e.g., a surface of a tissue of a subject). The self-righting articles described herein may comprise one or more tissue engaging surfaces configured to engage (e.g., interface with, inject into, anchor) with a surface (e.g., a surface of a tissue of a subject). In some embodiments, the self-righting article may have a particular shape and/or distribution of density (or mass) which, for example, enables the self-righting behavior of the article. In some embodiments, the self-righting article may comprise a tissue interfacing component and/or a pharmaceutical agent (e.g., for delivery of the active pharmaceutical agent to a location internal of the subject). In some cases, upon contact of the tissue with the tissue engaging surface of the article, the self-righting article may be configured to release one or more tissue interfacing components. In some cases, the tissue interfacing component is associated with a self-actuating component. For example, the self-righting article may comprise a self-actuating component configured, upon exposure to a fluid, to release the tissue interfacing component from the self-righting article. In some cases, the tissue interfacing component may comprise and/or be associated with the pharmaceutical agent (e.g., for delivery to a location internal to a subject). |
| FILED | Thursday, May 17, 2018 |
| APPL NO | 16/614083 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/14503 (20130101) A61B 5/14539 (20130101) A61B 10/02 (20130101) A61B 10/0233 (20130101) A61B 2010/0208 (20130101) Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 3/07 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0002 (20130101) A61K 9/0012 (20130101) A61K 9/0021 (20130101) A61K 9/0065 (20130101) A61K 9/0092 (20130101) A61K 9/4808 (20130101) Original (OR) Class A61K 9/4866 (20130101) A61K 38/28 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/158 (20130101) A61M 5/329 (20130101) A61M 5/2033 (20130101) A61M 5/3295 (20130101) A61M 5/14276 (20130101) A61M 31/002 (20130101) A61M 37/0015 (20130101) A61M 2005/1585 (20130101) A61M 2005/14284 (20130101) A61M 2037/0023 (20130101) A61M 2037/0053 (20130101) A61M 2205/21 (20130101) A61M 2205/0238 (20130101) A61M 2210/106 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/325 (20130101) A61N 1/0509 (20130101) A61N 1/36007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11179360 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Cincinnati (Cincinnati, Ohio) |
| ASSIGNEE(S) | University of Cincinnati (Cincinnati, Ohio) |
| INVENTOR(S) | Jianjun Chen (Cincinnati, Ohio); Rui Su (Cincinnati, Ohio) |
| ABSTRACT | Pharmaceutical compositions, kits and methods for treating tumors such as glioma and cancers such as leukemia with (R)-2-hydroxyglutarate (R-2HG) are provided, along with therapeutic regimens including treatment of a patient suffering from glioma or leukemia with a MYC-signaling inhibitor followed by or cotemporaneous with treatment with R-2HG, and optionally other chemotherapeutic agents. |
| FILED | Thursday, November 02, 2017 |
| APPL NO | 16/346654 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/194 (20130101) Original (OR) Class A61K 31/203 (20130101) A61K 31/704 (20130101) A61K 31/7068 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11179361 | Rahbar et al. |
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| FUNDED BY |
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| APPLICANT(S) | CITY OF HOPE (Duarte, California) |
| ASSIGNEE(S) | CITY OF HOPE (Duarte, California) |
| INVENTOR(S) | Samuel Rahbar (Beverly Hills, California); Timothy W. Synold (Monrovia, California); John Termini (Altadena, California); Gerald Wuenschell (Duarte, California); Daniel Tamae (Duarte, California) |
| ABSTRACT | Methods of quantifying a N2-(1-carboxyethyl)-2′-deoxyguanosine (CEdG) levels in biological samples and comparing those levels to known normal levels can diagnose a number of metabolic disorders or complications associated therewith, including diabetes, its associated complications, and cancer. Methods can also determine whether therapies for disorders are effective by measuring CEdG levels before and after treatment. Measurement of CEdG levels is achieved by using liquid chromatography electrospray ionization tandem mass spectrometry. |
| FILED | Friday, February 02, 2018 |
| APPL NO | 15/887857 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/121 (20130101) A61K 31/195 (20130101) Original (OR) Class A61K 45/06 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/7233 (20130101) G01N 30/7266 (20130101) G01N 33/6893 (20130101) G01N 2030/045 (20130101) G01N 2030/8827 (20130101) G01N 2030/8868 (20130101) G01N 2800/042 (20130101) G01N 2800/56 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11179374 | Sell et al. |
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| FUNDED BY |
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| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Christian Sell (Conshohocken, Pennsylvania); Timothy Nacarelli (Norristown, Pennsylvania); Ashley Azar (North Wales, Pennsylvania) |
| ABSTRACT | The present invention includes compositions and methods for treating or preventing certain dermal disorders including dermal atrophy, pseudoscars, actinic keratosis, seborrheic or actinic keratoses, lentigines, focal areas of dermal thickening, and coarse wrinkles. In certain embodiments, the compositions useful within the invention comprise a therapeutically effective amount of a mTORC1 inhibitor and a dermatologically acceptable carrier. |
| FILED | Thursday, May 21, 2020 |
| APPL NO | 16/880186 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/436 (20130101) Original (OR) Class A61K 31/501 (20130101) A61K 31/519 (20130101) A61K 31/5377 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11179379 | Blobel et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (Philadelphia, Pennsylvania); THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); COLD SPRING HARBOR LABORATORY (Cold Spring Harbor, New York) |
| ASSIGNEE(S) | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (Philadelphia, Pennsylvania); THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); COLD SPRING HARBOR LABORATORY (Cold Spring Harbor, New York) |
| INVENTOR(S) | Gerd Blobel (Bala Cynwyd, Pennsylvania); Jeremy Grevet (Philadelphia, Pennsylvania); Junwei Shi (Philadelphia, Pennsylvania); Christopher Vakoc (Cold Spring Harbor, New York) |
| ABSTRACT | Methods and compositions for producing fetal hemoglobin and treating a hemoglobinopathy or thalassemia are disclosed. |
| FILED | Tuesday, January 30, 2018 |
| APPL NO | 16/478651 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/454 (20130101) Original (OR) Class A61K 31/517 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/06 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11179385 | Xu et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Xiaowei Xu (Monmouth Drive, New Jersey); Shujing Liu (Philadelphia, Pennsylvania); Alain Rook (Wynnewood, Pennsylvania); Pankaj Karande (Troy, New York) |
| ABSTRACT | Compositions and methods for treatment of viral skin disease, precancerous and cancerous skin disease, and other neoplasms are disclosed. |
| FILED | Thursday, June 30, 2016 |
| APPL NO | 15/740147 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0019 (20130101) A61K 31/444 (20130101) A61K 31/444 (20130101) A61K 31/4745 (20130101) Original (OR) Class A61K 31/4745 (20130101) A61K 38/217 (20130101) A61K 39/00 (20130101) A61K 39/39558 (20130101) A61K 41/0057 (20130101) A61K 45/06 (20130101) A61K 47/12 (20130101) A61K 47/14 (20130101) A61K 47/20 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/12 (20180101) A61P 35/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11179412 | Tang et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Daolin Tang (Dallas, Texas); Timothy Billiar (Presto, Pennsylvania); Ling Zeng (Chongqing, China PRC) |
| ABSTRACT | A method of treating a patient having an elevated inflammatory response, such as an elevated Type I interferon response, is provided. The method can be used to treat sepsis. The method comprises administering to a patient having an elevated inflammatory response, an inhibitor of anaplastic lymphoma kinase (ALK inhibitors) or expression of ALK, in an amount effective to treat the elevated inflammatory response. |
| FILED | Tuesday, December 04, 2018 |
| APPL NO | 16/209206 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/439 (20130101) A61K 31/506 (20130101) A61K 31/675 (20130101) A61K 31/7105 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/06 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1136 (20130101) C12N 2310/14 (20130101) C12N 2320/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11179416 | Sharma et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| INVENTOR(S) | Blanka Sharma (Gainesville, Florida); Isaac Adjei (Gainesville, Florida); Shreedevi Kumar (Gainesville, Florida) |
| ABSTRACT | The present disclosure relates to manganese dioxide nanoparticles and their use in treatment of oxidative stress and conditions related to or characterized by oxidative stress, including osteoarthritis. |
| FILED | Wednesday, February 20, 2019 |
| APPL NO | 16/971399 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/1641 (20130101) A61K 9/1694 (20130101) A61K 33/32 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11179436 | Khaled et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Annette Khaled (Orlando, Florida); Rebecca Boohaker (Orlando, Florida); Michael Lee (Orlando, Florida); Jesus Perez Figueroa (Orlando, Florida) |
| ABSTRACT | In an aspect, the invention relates to compositions and methods for permeabilizing membranes of cells. In an aspect, the invention relates to compositions and methods for killing cells. In an aspect, the invention relates to compositions and methods of permeabilizing the membranes of cancer cells or microbial cells. |
| FILED | Tuesday, December 18, 2018 |
| APPL NO | 16/224004 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 43/38 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/513 (20130101) A61K 9/5153 (20130101) A61K 38/10 (20130101) Original (OR) Class A61K 38/16 (20130101) A61K 38/1761 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 7/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11179439 | John et al. |
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| FUNDED BY |
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| APPLICANT(S) | MandalMed, Inc. (San Francisco, California); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | MandalMed, Inc. (San Francisco, California); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Constance M. John (San Francisco, California); Meenakshi Gaur (San Francisco, California); Matthew L. Springer (San Francisco, California); Xiaoyin Wang (San Francisco, California) |
| ABSTRACT | Provided herein are methods and compositions for preventing and treating damage to the heart subsequent to myocardial infarction (MI) resulting from harmful fibrotic remodeling, thereby improving cardiac function and reducing mortality from subsequent heart failure. |
| FILED | Tuesday, June 18, 2019 |
| APPL NO | 16/445086 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0021 (20130101) A61K 38/1732 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11179476 | Law et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Shek Hang Benedict Law (New York, New York); Ching-Hsuan Tung (New York, New York); Vanessa Bellat (New York, New York) |
| ABSTRACT | The disclosure provides compositions comprising peptide-based nanofiber precursors and methods of using the same to inhibit cancerous cell growth and/or to deliver therapeutic or diagnostic agents to cells, e.g., cancerous cells. The compositions of the present technology include peptide-based nanofiber precursors as well as carrier complexes comprising a therapeutic or diagnostic agent, and a peptide-based nanofiber precursor. Also provided herein are methods for delivering a therapeutic or diagnostic agent to a cell comprising contacting the cell with a carrier complex including a therapeutic or diagnostic agent, and a peptide-based nanofiber precursor. |
| FILED | Friday, October 18, 2019 |
| APPL NO | 16/657748 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 9/70 (20130101) A61K 31/167 (20130101) A61K 31/704 (20130101) A61K 31/5365 (20130101) A61K 38/50 (20130101) A61K 38/063 (20130101) A61K 38/212 (20130101) A61K 38/2013 (20130101) A61K 38/2073 (20130101) A61K 47/42 (20130101) A61K 47/60 (20170801) A61K 47/65 (20170801) A61K 47/6953 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Enzymes C12Y 305/01001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11179484 | Schultz et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| ASSIGNEE(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| INVENTOR(S) | Michael K. Schultz (Iowa City, Iowa); Frances L. Johnson (Iowa City, Iowa); Somya Kapoor (Iowa City, Iowa); Dongyoul Lee (Iowa City, Iowa); Mengshi Li (Iowa City, Iowa); Molly Martin (Iowa City, Iowa) |
| ABSTRACT | The invention provides compositions, kits and methods to treat a hyperproliferative disorder with an agent that increases expression of MCR1 and an MCR1 ligand. The invention also provides a method of treating drug-resistant melanoma, comprising administering an MCR1 ligand to a patient in need thereof. The present invention also provides in certain embodiments a melanoma-targeting conjugate comprising Formula (I): T-L-X wherein T is a MCR1 ligand, L is a linker, and X an anti-cancer composition, for the therapeutic treatment of a hyperproliferative disorder. The present invention also provides methods, kits and uses of the conjugate of Formula (I). |
| FILED | Monday, June 26, 2017 |
| APPL NO | 16/312846 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/167 (20130101) A61K 31/192 (20130101) A61K 31/437 (20130101) A61K 31/519 (20130101) A61K 31/4427 (20130101) A61K 38/08 (20130101) A61K 47/60 (20170801) A61K 47/64 (20170801) A61K 47/545 (20170801) A61K 47/546 (20170801) A61K 51/048 (20130101) A61K 51/0482 (20130101) Original (OR) Class A61K 51/0497 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11179494 | Paten et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Jeffrey A. Paten (Hyde Park, Massachusetts); Jeffrey W. Ruberti (Lexington, Massachusetts) |
| ABSTRACT | Methods and devices for tissue remodeling and repair of collagenous tissues, including tendons, ligaments, and bone, as well as scalable connective tissue manufacturing, are provided. Collagen fibers are assembled by extensional strain-induced flow crystallization of collagen monomers. Extensional strain also drives the fusion of already formed short collagen fibrils to produce long-range, continuous fibers. Wearable devices for controlled tissue remodeling and wound healing deliver a tissue remodeling solution to a tissue repair site. The remodeling solution, together with appropriate application of strain to the tissue remodeling site, accelerate healing, prevent injury, and reduce scar formation. |
| FILED | Tuesday, December 15, 2015 |
| APPL NO | 15/536358 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/02 (20130101) A61H 1/008 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/39 (20130101) A61K 38/39 (20130101) A61K 38/47 (20130101) A61K 38/47 (20130101) A61K 38/4873 (20130101) A61K 38/4873 (20130101) A61K 38/4886 (20130101) A61K 38/4886 (20130101) A61K 47/183 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/24 (20130101) Original (OR) Class A61L 27/50 (20130101) A61L 27/54 (20130101) A61L 2300/41 (20130101) A61L 2300/426 (20130101) A61L 2400/06 (20130101) A61L 2430/10 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/14 (20130101) A61M 5/142 (20130101) A61M 5/14248 (20130101) A61M 2202/095 (20130101) A61M 2205/50 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0456 (20130101) Enzymes C12Y 302/01035 (20130101) C12Y 304/24 (20130101) C12Y 304/22001 (20130101) C12Y 304/24007 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/00 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 4/00 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2509/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11179498 | Bhumiratana et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Sarindr Bhumiratana (Davis, California); Gordana Vunjak-Novakovic (New York, New York) |
| ABSTRACT | Medical devices having engineered mechanically functional cartilage from adult human mesenchymal stem cells and method for making same. |
| FILED | Friday, July 21, 2017 |
| APPL NO | 15/656681 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/3094 (20130101) A61F 2/30756 (20130101) A61F 2002/30762 (20130101) A61F 2002/30766 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/46 (20130101) A61L 27/46 (20130101) A61L 27/50 (20130101) A61L 27/56 (20130101) A61L 27/425 (20130101) A61L 27/3608 (20130101) A61L 27/3612 (20130101) Original (OR) Class A61L 27/3834 (20130101) A61L 2400/06 (20130101) A61L 2430/06 (20130101) A61L 2430/10 (20130101) Compositions of Macromolecular Compounds C08L 89/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11179581 | Qin |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Foundation for The State University of New York (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for the State University of New York (Albany, New York) |
| INVENTOR(S) | Yi-Xian Qin (Setauket, New York) |
| ABSTRACT | Stimulating cell activity within a tissue is performed by an ultrasound array transducer having a plurality of transducer elements and a controller that actuates a plurality of transducer elements to emit focused acoustic energy to a plurality of focal zone locations in a scan direction at a focal zone scan rate. The actuation of the plurality of transducer elements to emit focused acoustic energy to the plurality of focal zone locations in the scan direction at the focal zone scan rate is repeated for a plurality of sweep cycles at a sweep rate which stimulates cells for optimal tissue growth. |
| FILED | Tuesday, March 08, 2016 |
| APPL NO | 15/557268 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/02 (20130101) Original (OR) Class A61N 2007/0095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11179717 | Lopez |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Gabriel P. Lopez (Durham, North Carolina) |
| ABSTRACT | A kit for detection of an analyte of interest in a liquid sample, and methods of using, are provided. The kit may include a pipette and a disposable pipette tip configured to engage the pipette. The pipette tip may define an acoustic channel configured for allowing flow-through of a liquid. The kit may also include a vibratory device in communication with the acoustic channel and configured for imparting a vibratory force thereto. The impartation of the vibratory force may create standing acoustic waves, thereby separating any negative acoustic contrast particles (NACPs) from the remaining contents of the liquid sample. The NACPs may capable of biospecific recognition of the analyte of interest, thereby separating the analytes of interest, which can then be collected or analyzed accordingly. |
| FILED | Tuesday, July 03, 2018 |
| APPL NO | 16/026581 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/0275 (20130101) Original (OR) Class B01L 2200/0652 (20130101) B01L 2200/0668 (20130101) B01L 2300/0832 (20130101) B01L 2300/0858 (20130101) B01L 2400/0433 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4077 (20130101) G01N 2001/4094 (20130101) G01N 2015/1006 (20130101) G01N 2035/1048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180481 | Arora et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York) |
| ASSIGNEE(S) | NEW YORK UNIVERSITY (New York, New York) |
| INVENTOR(S) | Paramjit S. Arora (Cold Spring Harbor, New York); Brooke Bullock Lao (Leesville, South Carolina); Danielle Guarracino (Princeton, New Jersey); Richard Bonneau (New York, New York); Kevin Drew (Austin, Texas) |
| ABSTRACT | The present invention relates to oligooxopiperazines for modulating the p53-Mdm2 interaction. Exemplary oligooxopiperazines include those of Formula IA, Formula IB, and Formula IC below (wherein the various substituents are as defined herein). Methods of using the oligooxopiperazines are also disclosed. |
| FILED | Wednesday, April 15, 2015 |
| APPL NO | 15/304490 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 241/08 (20130101) C07D 403/06 (20130101) Original (OR) Class C07D 403/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180489 | Thorpe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia); Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
| ASSIGNEE(S) | U niversity of Virginia Patent Foundation (Charlottesville, Virginia); Virginia Tech Entellectuzal Properties, Inc. (Blacksburg, Virginia) |
| INVENTOR(S) | Steven Brandon Thorpe (Palmyra, Virginia); Webster L. Santos (Blacksburg, Virginia); Kevin R. Lynch (Charlottesville, Virginia) |
| ABSTRACT | Sphingosine kinases are enzymes that catalyze the biosynthesis of sphingosine-1-phosphate. The invention provides prodrugs of compounds that are effective for inhibition of sphingosine kinase type 1, sphingosine kinase type 2, or both, according to formula (I) as described herein. Formula I compounds are useful in the treatment of a range of diseases wherein increasing the level of sphingosine-1-phosphate in blood is medically indicated. The invention also provides pharmaceutical compositions of Formula I compounds. |
| FILED | Wednesday, March 29, 2017 |
| APPL NO | 16/089939 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 413/04 (20130101) C07D 413/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180492 | Tan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan-Kettering Cancer Center (New York, New York); The Regents of the University of California (Oakland, California); University of Central Florida Research Foundation, Inc. (Orlando, Florida); The Broad Institute, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida); The Regents of the University of California (Oakland, California); Memorial Sloan-Kettering Cancer Center (New York, New York); The Broad Institute, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Derek Shieh Tan (New York, New York); Corinne N. Foley (New York, New York); Gustavo Moura-Letts (New York, New York); James McKerrow (New York, New York); Sivaraman Dandapani (Wakefield, Massachusetts); Rahul Edwankar (New York, New York); Alyssa Verano (New York, New York); Debopam Chakrabarti (Winter Springs, Florida); Bracken Roberts (Oviedo, Florida) |
| ABSTRACT | The present disclosure provides compounds of Formula (I′), Formula (II), and Formula (III). The compounds described herein may useful in treating and/or preventing protozoan infections in a subject in need thereof, treating and/or preventing trypanosomal infections (e.g., Trypanosoma cruzi (T. cruzi) or Trypanosoma brucei infections) and/or plasmodial infections in a subject in need thereof, treating and/or preventing diseases in a subject in need thereof (e.g., Chagas disease, malaria, and/or sleeping sickness), and may be useful in treating and/or preventing infectious diseases in a subject in need thereof. Also provided in the present disclosure are pharmaceutical compositions, kits, methods, and uses including a compound described herein. |
| FILED | Tuesday, January 17, 2017 |
| APPL NO | 16/070137 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 33/00 (20180101) A61P 33/06 (20180101) Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180498 | Krogstad et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Paul Krogstad (Los Angeles, California); Michael E. Jung (Los Angeles, California); Jun Zuo (Los Angeles, California); Yanpeng Xing (Los Angeles, California) |
| ABSTRACT | The present technology provides compounds according to Formula I expected to be useful in inhibiting an enterovirus, paramyxovirus, respiratory virus, flaviviridae virus, bunyaviridae virus, togaviridae virus, or rabies virus in a cell and/or treating subjects suffering from an enterovirus, paramyxovirus, respiratory virus, flaviviridae virus, bunyaviridae virus, togaviridae virus, or rabies virus. |
| FILED | Wednesday, September 26, 2018 |
| APPL NO | 16/649961 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class C07D 487/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180507 | Cui et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Xinyan Cui (Wexford, Pennsylvania); Bin Cao (Allison Park, Pennsylvania) |
| ABSTRACT | A method of forming a compound having the formula (I′): (I′) includes the reaction: (II′) in the presence of a base, wherein X is a halo atom selected from the group consisting of Cl, Br and I. |
| FILED | Monday, July 10, 2017 |
| APPL NO | 16/315954 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Heterocyclic Compounds C07D 495/04 (20130101) Original (OR) Class Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 2/58 (20130101) C08F 28/06 (20130101) C08F 2400/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180557 | Noelle |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | KING'S COLLEGE LONDON (London, United Kingdom); THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| ASSIGNEE(S) | KING'S COLLEGE LONDON (London, United Kingdom); THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | Randolph J. Noelle (Plainfield, New Hampshire) |
| ABSTRACT | The present disclosure relates to compositions and therapeutic methods for activating an immune response in a patient in need thereof. In a preferred embodiment, the subject methods and compositions are able to antagonize the activity of VISTA, a naturally occurring “checkpoint” protein which contributes to immune tolerance, optionally in combination with an antagonist of a second checkpoint pathway such as PD-1. For example, such methods and compositions may be suitable for preventing and treating colon cancer or another cancer. An exemplary VISTA antagonist, specifically, an anti-VISTA antibody, is demonstrated herein to activate an immune response against cancer cells in vitro and in vivo, thereby conferring protective anti-tumor immunity which decreased tumor burden. Additionally, an additive benefit was observed when a VISTA antagonist was used in combination with a second checkpoint protein antagonist, specifically, an antibody against PD-1 ligand (PD-L1). |
| FILED | Tuesday, December 19, 2017 |
| APPL NO | 15/847132 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 14/70532 (20130101) C07K 16/2803 (20130101) C07K 16/2827 (20130101) Original (OR) Class C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180565 | McGovern et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| ASSIGNEE(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| INVENTOR(S) | Dermot McGovern (Los Angeles, California); Stephan Targan (Santa Monica, California); Dalin Li (Walnut, California) |
| ABSTRACT | The aspects disclosed herein describe methods of identifying a subject that is non-responsive to anti-TNF therapy. The aspects disclosed herein further provide for a method of selecting a therapy for a subject with Inflammatory Bowel Disease (IBD), and treating the subject with the therapy. |
| FILED | Tuesday, March 10, 2020 |
| APPL NO | 16/814641 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/3955 (20130101) A61K 39/39541 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) Peptides C07K 16/241 (20130101) C07K 16/2875 (20130101) Original (OR) Class C07K 2317/76 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6827 (20130101) C12Q 1/6883 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6854 (20130101) G01N 33/6863 (20130101) G01N 2800/52 (20130101) G01N 2800/56 (20130101) G01N 2800/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180570 | Ho et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ImaginAb, Inc. (Inglewood, California) |
| ASSIGNEE(S) | ImaginAb, Inc. (Inglewood, California) |
| INVENTOR(S) | David T. Ho (Long Beach, California); Tove Olafsen (Reseda, California); Arye Lipman (El Segundo, California) |
| ABSTRACT | In one embodiment, a minibody monomer that binds PSMA is provided. The minibody monomer is encoded by a nucleotide sequence comprising, from N-terminus to C-terminus, an scFv sequence that can bind PSMA, an artificial hinge sequence, and a human IgG CH3 sequence. In another embodiment, a CysDB monomer that binds PSMA is provided. The CysDB monomer may be encoded by a nucleotide sequence comprising, from N-terminus to C-terminus, an scFv sequence that can bind PSMA and a cysteine tail. In other embodiments, methods for diagnosing or treating a cancer associated with PSMA expression in a subject are provided. |
| FILED | Tuesday, February 12, 2019 |
| APPL NO | 16/273948 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/1072 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/3069 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/56 (20130101) C07K 2317/64 (20130101) C07K 2317/77 (20130101) C07K 2317/90 (20130101) C07K 2317/526 (20130101) C07K 2317/622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180574 | Szeto et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell Research Foundation, Inc. (New York, New York) |
| ASSIGNEE(S) | CORNELL RESEARCH FOUNDATION INC. (New York, New York) |
| INVENTOR(S) | Hazel H. Szeto (New York, New York); Kesheng Zhao (Jackson Heights, New York); Hugh Robertson (New York, New York); Alex V. Birk (Woodhaven, New York) |
| ABSTRACT | The invention relates to carrier complexes and methods for delivering molecules to cells. The carrier complexes comprises a molecule and an aromatic cationic peptide in accordance with the invention. In one embodiment, the method for delivering a molecule to a cell comprises contacting the cell with a carrier complex. In another embodiment, the method for delivering a molecule to a cell comprises contacting the cell with a molecule and an aromatic cationic peptide. |
| FILED | Thursday, February 20, 2020 |
| APPL NO | 16/796063 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 38/47 (20130101) A61K 47/64 (20170801) A61K 47/645 (20170801) Peptides C07K 5/08 (20130101) C07K 5/1016 (20130101) C07K 5/1019 (20130101) C07K 17/00 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/96 (20130101) C12N 9/2471 (20130101) C12N 15/87 (20130101) C12N 15/113 (20130101) C12N 2310/3513 (20130101) C12N 2320/32 (20130101) Enzymes C12Y 302/01023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180724 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Abraham P. Lee (Irvine, California); Xiaolin Wang (Shanghai, China PRC); Duc Phan (Fountain Valley, California); Christopher C. W. Hughes (Irvine, California); Steven C. George (St. Louis, Missouri) |
| ABSTRACT | A pressure regulator module for a chip-based microfluidic platform is provided. The module includes a microfluidic channel for passing flowable material from the inlet region through the outlet region and into a downstream compartment; one or more microvalves fluidly connected to the microfluidic channel and upstream of the outlet region; and one or more reservoirs fluidly connected to the microvalves, for receiving flowable material diverted by the microvalves, where a flow of flowable material passing from the inlet region toward the downstream compartment is at least partially diverted by the microvalves into the reservoirs as a result of a pressure increase in the microfluidic channel. In some versions, the microvalves are capillary burst valves. A microfluidic chip containing the module and a method of using the module are provided. |
| FILED | Monday, October 24, 2016 |
| APPL NO | 15/333183 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502738 (20130101) B01L 3/502761 (20130101) B01L 2200/0647 (20130101) B01L 2300/0864 (20130101) B01L 2400/0688 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/16 (20130101) Original (OR) Class C12M 29/10 (20130101) C12M 41/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180730 | Regev et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Aviv Regev (Cambridge, Massachusetts); Ana Carrizosa Anderson (Brookline, Massachusetts); Le Cong (Cambridge, Massachusetts); Vijay K. Kuchroo (Chestnut Hill, Massachusetts); Meromit Singer (Somerville, Massachusetts); Chao Wang (Cambridge, Massachusetts) |
| ABSTRACT | The present invention provides markers, marker signatures and molecular targets that correlate with dysfunction of immune cells and are advantageously independent of the immune cell activation status. The present markers, marker signatures and molecular targets provide for new ways to evaluate and modulate immune responses. Specifically, GATA3 and/or FOXO1 modulation are provided for use as markers, marker signatures and molecular targets. Therapeutic methods are also provided to treat a patient in need thereof who would benefit from an increased immune response. |
| FILED | Monday, April 30, 2018 |
| APPL NO | 15/966290 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 39/0011 (20130101) A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0638 (20130101) Original (OR) Class C12N 15/1079 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/106 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/505 (20130101) G01N 33/5023 (20130101) G01N 33/5047 (20130101) G01N 2333/4703 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180735 | Neal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | James Neal (San Mateo, California); Calvin Jay Kuo (Palo Alto, California) |
| ABSTRACT | Functional in vitro assays are provided for determining patient specific responsiveness to immunotherapy agents within a clinically actionable time frame. |
| FILED | Wednesday, October 25, 2017 |
| APPL NO | 15/793249 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39558 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/2818 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 5/0693 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/5047 (20130101) G01N 33/57484 (20130101) G01N 2800/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180737 | Kawaoka et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
| INVENTOR(S) | Yoshihiro Kawaoka (Middleton, Wisconsin); Gabriele Neumann (Madison, Wisconsin) |
| ABSTRACT | Compositions and methods to prepare influenza virus-like particles (VLPs) are provided. |
| FILED | Wednesday, August 21, 2019 |
| APPL NO | 16/547262 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 2039/5254 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 2760/16123 (20130101) C12N 2760/16134 (20130101) C12N 2760/16151 (20130101) C12N 2760/16152 (20130101) C12N 2760/16223 (20130101) C12N 2760/16234 (20130101) C12N 2760/16251 (20130101) C12N 2760/16252 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180748 | Raines et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Ronald T. Raines (Madison, Wisconsin); Kalie Mix (Madison, Wisconsin) |
| ABSTRACT | Methods and reagents for esterification of biological molecules including proteins, polypeptides and peptides. Diazo compounds of formula I: where R is hydrogen, an alkyl, an alkenyl or an alkynyl, RA represents 1-5 substituents on the indicated phenyl ring and RM is an organic group. RM includes a label, a cell penetrating group, a cell targeting group, or a reactive group or latent reactive group for reaction to bond to a label, a cell penetrating group, or a cell targeting group, among other organic groups useful for esterification of biological molecules. Also provided are diazo compounds which are bifunctional and trifunctional coupling reagents as well as reagents for the synthesis of compounds of formula I. |
| FILED | Monday, September 30, 2019 |
| APPL NO | 16/588224 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 231/12 (20130101) C07C 231/12 (20130101) C07C 235/34 (20130101) C07C 245/18 (20130101) C07C 269/06 (20130101) C07C 269/06 (20130101) C07C 271/22 (20130101) C07C 319/12 (20130101) C07C 319/12 (20130101) C07C 323/52 (20130101) Heterocyclic Compounds C07D 207/46 (20130101) Peptides C07K 1/13 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/96 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180751 | Koonin et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts); Rutgers, the State University of New Jersey (New Brunswick, New Jersey); The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland); Skolkovo Institute of Science and Technology (Moscow, Russian Federation) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts); Rutgers, the State University of New Jersey (New Brunswick, New Jersey); The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); Skolkovo Institute of Science and Technology (Moscow, Russian Federation) |
| INVENTOR(S) | Eugene Koonin (Bethesda, Maryland); Feng Zhang (Cambridge, Massachusetts); Yuri I. Wolf (Bethesda, Maryland); Sergey Shmakov (Moscow, Russian Federation); Konstantin Severinov (Piscataway, New Jersey); Ekaterina Semenova (Piscataway, New Jersey); Leonid Minakhin (Piscataway, New Jersey); Kira S. Makarova (Bethesda, Maryland); Silvana Konermann (Zurich, Switzerland); Julia Joung (Boston, Massachusetts); Jonathan S. Gootenberg (Cambridge, Massachusetts); Omar O. Abudayyeh (Boston, Massachusetts) |
| ABSTRACT | The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered DNA or RNA-targeting systems comprising a novel DNA or RNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA. |
| FILED | Thursday, December 14, 2017 |
| APPL NO | 15/842073 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/102 (20130101) Original (OR) Class C12N 15/8213 (20130101) C12N 2310/20 (20170501) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180758 | Thomas et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | David Lee Thomas (Lutherville, Maryland); Ashwin Balagopal (Columbia, Maryland); Ramy El-Diwany (Baltimore, Maryland); Robert Siliciano (Baltimore, Maryland); Joel Blankson (Baltimore, Maryland); Stuart C Ray (Lutherville, Maryland); Michel Anand Chattergoon (Baltimore, Maryland); Justin Bailey (Baltimore, Maryland) |
| ABSTRACT | Three proteins, BCL-G (BCL2L14), CMPK2, and LAMP3, were discovered to independently restrict HIV-1 replication both in-vivo and in-vitro. Methods are described wherein subjects are given an effective amount of a pharmaceutical composition comprising a protein selected from the group consisting of BCL-G, CMPK2, LAMP3, functional parts thereof, recombinant proteins thereof, and combinations thereof, for the purpose of treating or preventing HIV. |
| FILED | Friday, February 24, 2017 |
| APPL NO | 16/078760 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/45 (20130101) A61K 38/1709 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1132 (20130101) Original (OR) Class Enzymes C12Y 207/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180760 | Zack et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Donald J. Zack (Baltimore, Maryland); Derek S. Welsbie (Lutherville-Timonium, Maryland) |
| ABSTRACT | Drug targets, pathways, kits and methods for treating conditions related to neurodegeneration or ocular disease, are disclosed. |
| FILED | Monday, March 11, 2013 |
| APPL NO | 14/383982 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/553 (20130101) A61K 31/713 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2320/30 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) C12Q 1/6883 (20130101) C12Q 2600/136 (20130101) Enzymes C12Y 207/10 (20130101) C12Y 207/11 (20130101) C12Y 207/99 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2500/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180765 | Curtiss, III et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Arizona Board of Regents for and on Behalf of Arizona State University (Scottsdale, Arizona); The Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | The Arizona Board of Regents for and on behalf of Arizona State University (Tempe, Arizona); The Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Roy Curtiss, III (Gainesville, Florida); Shifeng Wang (Gainesville, Florida); Soo-Young Wanda (Gainesville, Florida); Wei Kong (Phoenix, Arizona) |
| ABSTRACT | The invention relates to compositions and methods for making and using recombinant bacteria that are capable of regulated attenuation and/or regulated expression of one or more antigens of interest. |
| FILED | Tuesday, August 11, 2020 |
| APPL NO | 16/990033 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) A61K 39/00 (20130101) A61K 2035/11 (20130101) A61K 2039/522 (20130101) A61K 2039/523 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/36 (20130101) C12N 15/74 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180778 | Savage et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | David Frank Savage (Berkeley, California); Jennifer A. Doudna (Berkeley, California); Benjamin L. Oakes (Berkeley, California); Rayka Yokoo (Berkeley, California) |
| ABSTRACT | The present disclosure provides (i) RNA-guided polypeptides (e.g., circular permuted Cas9 proteins) in which the N-terminal end of an N-terminal fragment of a parent RNA-guided polypeptide (e.g., a parent Cas9 protein) is fused (e.g., via linker) to the C-terminal end of the C-terminal fragment (thereby generating new N- and C-termini), (ii) conditionally active RNA-guided polypeptides (e.g., conditionally active circular permuted Cas9 proteins), and (iiii) Cas9 fusion polypeptides that include an internal insertion of a heterologous polypeptide; as well as methods that employ the above polypeptides. |
| FILED | Thursday, November 09, 2017 |
| APPL NO | 16/342862 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 2319/50 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/74 (20130101) C12N 15/79 (20130101) C12N 15/113 (20130101) C12N 15/907 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180792 | O'Connell et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Mitchell R. O'Connell (Berkeley, California); Jennifer A. Doudna (Berkeley, California) |
| ABSTRACT | The present disclosure provides compositions and methods for labeling a single stranded target nucleic acid. Subject compositions include a Cas9 protein, a Cas9 guide RNA, and a quenched PAMmer. A subject quenched PAMmer is a single stranded oligonucleotide having (i) a protospacer adjacent motif (PAM) sequence; (ii) a detectable label; (iii) a quencher moiety that quenches the detectable label; and (iv) at least one of: a specificity segment positioned 5′ of the PAM sequence, and an orientation segment positioned 3′ of the PAM sequence. In the subject methods, the Cas9 protein cleaves the quenched PAMmer at a cleavage site positioned between the detectable label and the quencher moiety to produce: (a) a first cleavage product that is hybridized with the target nucleic acid and comprises the detectable label; and (b) a second cleavage product that is not hybridized with the target nucleic acid and comprises the quencher moiety. |
| FILED | Wednesday, January 27, 2016 |
| APPL NO | 15/540227 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/701 (20130101) C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6818 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180803 | Vogelstein et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Nickolas Papadopoulos (Towson, Maryland); Isaac Kinde (Beaumont, California) |
| ABSTRACT | Though massively parallel sequencing instruments are in principle well-suited to the task of identification of mutations present in a small fraction of DNA templates, the error rates in such instruments are generally too high to allow confident identification of rare variants. An approach that can substantially increase the sensitivity of massively parallel sequencing instruments for this purpose is called “Safe-SeqS” for (Safe-Sequencing System) and includes (i) assignment of a unique identifier (UID) to each template molecule; (ii) amplification of each uniquely tagged template molecule to create UID-families; and (iii) redundant sequencing of the amplification products. PCR fragments with the same UID are truly mutant (“super-mutants”) if ≥95% of them contain the identical mutation. |
| FILED | Thursday, August 18, 2016 |
| APPL NO | 15/240034 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 1/6874 (20130101) C12Q 1/6876 (20130101) C12Q 2525/179 (20130101) C12Q 2525/191 (20130101) C12Q 2535/122 (20130101) C12Q 2563/179 (20130101) C12Q 2565/514 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180804 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Fei Chen (Cambridge, Massachusetts); Andrew C. Payne (Cambridge, Massachusetts); Jason D. Buenrostro (Cambridge, Massachusetts); Paul Reginato (Cambridge, Massachusetts); Edward Stuart Boyden (Chestnut Hill, Massachusetts); Shahar Alon (Cambridge, Massachusetts) |
| ABSTRACT | The present invention provides methods for analyzing polynucleotides such as genomic DNA. In some embodiments, the disclosure provides a method for preparing and amplifying a genomic DNA library in situ in a fixed biological sample. The method comprises treating a fixed biological sample with an insertional enzyme complex to produce tagged fragments of genomic DNA. The method further comprises circularizing the tagged fragments of genomic DNA. The method further comprises amplifying the tagged fragments of genomic DNA. |
| FILED | Tuesday, July 24, 2018 |
| APPL NO | 16/043950 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) C12N 15/1082 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) C12Q 1/6809 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 2525/155 (20130101) C12Q 2525/155 (20130101) C12Q 2525/191 (20130101) C12Q 2525/191 (20130101) C12Q 2525/301 (20130101) C12Q 2525/301 (20130101) C12Q 2531/125 (20130101) C12Q 2531/125 (20130101) C12Q 2543/101 (20130101) C12Q 2543/101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180807 | Hatchwell et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Research Foundation of State of University of New York (Albany, New York); Population Bio, Inc. (New York, New York) |
| ASSIGNEE(S) | Population Bio, Inc. (New York, New York); The Research Foundation of State of University of New York (Albany, New York) |
| INVENTOR(S) | Eli Hatchwell (Winchester, United Kingdom); Peggy S. Eis (Fitchburg, Wisconsin) |
| ABSTRACT | This document provides methods and materials related to genetic variations of neurological disorders. For example, this document provides methods for using such genetic variations to assess susceptibility of developing Parkinson's disease. |
| FILED | Friday, November 02, 2012 |
| APPL NO | 13/668049 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6809 (20130101) C12Q 1/6813 (20130101) C12Q 1/6827 (20130101) C12Q 1/6869 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/48 (20130101) G01N 33/5005 (20130101) G01N 33/5023 (20130101) G01N 33/5058 (20130101) G01N 33/6896 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180811 | Gladyshev |
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| FUNDED BY |
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| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Vadim Gladyshev (Brookline, Massachusetts) |
| ABSTRACT | The invention provides a collection of gene expression signatures that is linked to longevity. Also provided herein are assays, methods, and systems for identifying a treatment that can modulate lifespan or determining an effect of a treatment on a health profile of a subject by using the collection of gene expression signatures described herein. |
| FILED | Wednesday, June 20, 2018 |
| APPL NO | 16/013135 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180812 | Lyden et al. |
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| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York); SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (New York, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York); SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (New York, New York) |
| INVENTOR(S) | David C. Lyden (New York, New York); Hector Peinado Selgas (New York, New York); Haiying Zhang (New York, New York); Jacqueline Bromberg (New York, New York) |
| ABSTRACT | The present invention is directed to methods of diagnosing, prognosing, and monitoring cancer in a subject. These methods involves selecting a subject having cancer, and obtaining, from the selected subject, a sample containing exosomal DNA. The presence or absence of one or more mutations in BRAF and/or EGFR is detected in the exosomal DNA sample from the subject, and a diagnosis and/or prognosis of the cancer is given based on the detection of the one or more mutations in BRAF and/or EGFR. The present invention further relates to methods of treating a subject having cancer and/or monitoring a subject response to therapy based on the detection of one or more mutations in BRAF and/or EGFR in the exosomal DNA sample. |
| FILED | Friday, August 16, 2013 |
| APPL NO | 14/422102 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180813 | Robins et al. |
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| FUNDED BY |
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| APPLICANT(S) | Adaptive Biotechnologies Corporation (Seattle, Washington); Memorial Sloan-Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | Adaptive Biotechnologies Corporation (Seattle, Washington); Memorial Sloan-Kettering Cancer Center (New York, New York) |
| INVENTOR(S) | Harlan S. Robins (Seattle, Washington); Julie Rubinstein (Seattle, Washington); Ryan Emerson (Seattle, Washington); Jianda Yuan (New York, New York) |
| ABSTRACT | Disclosed are methods for determining the immunological status of the adaptive immune system of a subject by identifying and quantifying rearranged DNA (and/or subsequently transcribed RNA) sequences encoding T cell receptor (TCR) and/or immunoglobulin (IG) polypeptides, in a lymphoid DNA-containing sample from the subject. TCR and/or IG sequence diversity and sequence distribution permit immunocompetence and immune repertoire assessment and reflect the degree of T cell or B cell clonality and clonal expansion in the sample. Methods for stratifying patient populations on the basis of immunocompetence including likelihood of responding to immunotherapy are also described. |
| FILED | Friday, May 11, 2018 |
| APPL NO | 15/977258 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6851 (20130101) C12Q 1/6851 (20130101) C12Q 1/6883 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2537/143 (20130101) C12Q 2600/16 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) G16B 30/00 (20190201) G16B 30/10 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180816 | Alland et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| INVENTOR(S) | David Alland (Bernardsville, New Jersey); Soumitesh Chakravorty (Somerset, New Jersey) |
| ABSTRACT | The present invention relates to novel primers and sloppy molecular beacon and molecular beacon probes for amplifying segments from different genes in Mycobacterium tuberculosis for identifying the presence of M.tb DNA and/or resistance to anti-tuberculosis drugs. |
| FILED | Friday, October 09, 2015 |
| APPL NO | 15/517042 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/689 (20130101) Original (OR) Class C12Q 1/6865 (20130101) C12Q 2525/143 (20130101) C12Q 2525/185 (20130101) C12Q 2600/16 (20130101) C12Q 2600/112 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11181520 | Yuan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Baohong Yuan (Arlington, Texas); Bingbing Cheng (Dallas, Texas); Mingyuan Wei (Arlington, Texas) |
| ABSTRACT | Methods of imaging described herein comprises disposing a first and second ultrasound-switchable fluorophore in an environment; exposing the environment to an ultrasound beam to create an activation region; disposing the first and/or second fluorophore within the activation region to switch the first and/or second fluorophore from an off state to an on state; exposing the environment to a beam of electromagnetic radiation; detecting a first photoluminescence signal at a first location within the environment, the photoluminescence signal comprising at least one of a first ultrasound fluorescence signal emitted by the first fluorophore, a first fluorescence signal emitted by the second fluorophore, and a background signal; correlating the first photoluminescence signal with a first reference signal to generate a correlation coefficient for the first location; and multiplying the first photoluminescence signal by the first correlation coefficient for the first location to generate a first modified photoluminescence signal for the first location. |
| FILED | Thursday, June 27, 2019 |
| APPL NO | 16/455157 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0071 (20130101) A61B 8/481 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 41/0028 (20130101) A61K 49/0034 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 33/542 (20130101) G01N 33/5091 (20130101) Original (OR) Class G01N 2201/06113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11181529 | Weinberger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GenNext Technologies, Inc. (Montara, California) |
| ASSIGNEE(S) | GenNext Technologies, Inc. (Half Moon Bay, California) |
| INVENTOR(S) | Scot Randy Weinberger (Montara, California); Joshua S. Sharp (Oxford, Mississippi); Sandeep Misra (Oxford, Mississippi) |
| ABSTRACT | The three-dimensional structural analysis of pharmaceutical and/or biological molecules is performed by the reaction of OH radicals on the surfaces of the molecules of interest. Quantitation and/or completeness of the OH radicals are optionally measured using buffers intrinsic to the sample solutions as internal standards. Measurements of the reactions of these buffers with OH radicals provide an internal standard while avoiding the use of prior art internal standards that can have unwanted effects on the three-dimensional structures of interest. |
| FILED | Friday, March 05, 2021 |
| APPL NO | 17/193913 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/33 (20130101) G01N 21/6428 (20130101) G01N 33/6803 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 436/203332 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11181536 | Everson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado, a Body Corporate (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a Body Corporate (Denver, Colorado) |
| INVENTOR(S) | Gregory Thomas Everson (Englewood, Colorado); Steve Mark Helmke (Denver, Colorado) |
| ABSTRACT | A Disease Severity Index (DSI) is provided for assessment of chronic liver disease in a patient using non-invasive liver function test results. A DSI was derived from non-invasive liver function test results based on hepatic blood flow. The DSI is used in methods for prediction of clinical outcomes, prediction of response to antiviral treatment, and assessment of progression of chronic liver diseases. Non-invasive methods to diagnose three distinct categories of patients with Primary Sclerosing Cholangitis (PSC) are provided. The methods can be used to diagnose PSC patients as Slow Progressors, Moderate Progressors and Rapid Progressors. |
| FILED | Tuesday, July 02, 2019 |
| APPL NO | 16/460767 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/575 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) Original (OR) Class G01N 2800/085 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11181595 | Mehta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Bhairav Bipin Mehta (Cleveland, Ohio); Simone Coppo (Cleveland, Ohio); Michael Twieg (Cleveland, Ohio); Mark A. Griswold (Cleveland, Ohio) |
| ABSTRACT | Systems and methods are provided for acquiring imaging data from one or more resonance species that simultaneously produce individual magnetic resonance signals in a plurality of different slices. The data is acquired by simultaneously exciting, using a pTX RF coil array, a plurality of different slices such that at least some of the plurality of different slices are excited by transmitting RF energy from a subset of transmit channels in the pTX RF coil array. The method also includes comparing the data to a dictionary of signal evolutions to determine quantitative values for two or more parameters of the resonant species based, at least in part, on matching the data to a set of known signal evolutions stored in the dictionary. The method includes producing an image for each of the plurality of different slice locations, at least in part, on the quantitative values. |
| FILED | Friday, April 06, 2018 |
| APPL NO | 16/603312 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4835 (20130101) Original (OR) Class G01R 33/5608 (20130101) G01R 33/5612 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11181599 | Dosenbach et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri); Oregon Health and Science University (Portland, Oregon) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri); Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | Nico Dosenbach (St. Louis, Missouri); Jonathan Koller (St. Louis, Missouri); Andrew Van (St. Louis, Missouri); Abraham Snyder (St. Louis, Missouri); Amy Mirro (St. Louis, Missouri); Damien Fair (Portland, Oregon); Eric Earl (Portland, Oregon); Rachel Klein (Portland, Oregon); Oscar Miranda Dominguez (Portland, Oregon); Anders Perrone (Portland, Oregon) |
| ABSTRACT | Methods, computer-readable storage devices, and systems are described for reducing movement of a patient undergoing a magnetic resonance imaging (MRI) scan by aligning MRI data, the method implemented on a Framewise Integrated Real-time MRI Monitoring (“FIRMM”) computing device including at least one processor in communication with at least one memory device. Aspects of the method comprise receiving a data frame from the MRI system, aligning the received data frame to a preceding data frame, calculating motion of a body part between the received data frame and the preceding data frame, calculating total frame displacement, and excluding data frames with a cutoff above a pre-identified threshold of the total frame displacement. |
| FILED | Thursday, March 08, 2018 |
| APPL NO | 16/491413 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/0041 (20130101) G01R 33/4831 (20130101) G01R 33/5608 (20130101) G01R 33/56509 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11181601 | Roldán-Alzate et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Alejandro Roldán-Alzate (Madison, Wisconsin); David Rutkowski (Madison, Wisconsin); Diego Hernando Arribas (Madison, Wisconsin) |
| ABSTRACT | In some embodiments, the present disclosure discloses a magnetic resonance (MR) phantom. The MR phantom includes a housing, a base medium disposed within the housing, and one or more compartment extending through the base medium, the one or more compartment comprising a crosslinked acrylamide-based polymer. The MR phantoms may be used as calibration phantoms for magnetic resonance elastography sequences and diffusion weighted images. |
| FILED | Tuesday, May 19, 2020 |
| APPL NO | 16/878399 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/4244 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/30 (20130101) G01R 33/58 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11182888 | McCall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SPECTRAL MD, INC. (Dallas, Texas) |
| ASSIGNEE(S) | SPECTRAL MD, INC. (Dallas, Texas) |
| INVENTOR(S) | Brian McCall (Dallas, Texas); Wensheng Fan (Plano, Texas); Jason Dwight (Dallas, Texas); Zhicun Gao (Plano, Texas); Jeffrey E. Thatcher (Irving, Texas); John Michael DiMaio (Dallas, Texas) |
| ABSTRACT | Generally described, one or more aspects of the present application correspond to systems and techniques for spectral imaging using a multi-aperture system with curved multi-bandpass filters positioned over each aperture. The present disclosure further relates to techniques for implementing spectral unmixing and image registration to generate a spectral datacube using image information received from such imaging systems. Aspects of the present disclosure relate to using such a datacube to analyze the imaged object, for example to analyze tissue in a clinical setting, perform biometric recognition, or perform materials analysis. |
| FILED | Friday, August 07, 2020 |
| APPL NO | 16/988064 |
| ART UNIT | 2481 — Recording and Compression |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/50 (20130101) Original (OR) Class G06T 7/0012 (20130101) G06T 7/33 (20170101) G06T 7/55 (20170101) G06T 7/62 (20170101) G06T 2207/10036 (20130101) G06T 2207/10144 (20130101) G06T 2207/20221 (20130101) Pictorial Communication, e.g Television H04N 5/265 (20130101) H04N 5/2254 (20130101) H04N 5/2256 (20130101) H04N 5/2356 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11183604 | Goldan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Albany, New York) |
| INVENTOR(S) | Amirhossein Goldan (Stony Brook, New York); Wei Zhao (East Setauket, New York) |
| ABSTRACT | Provided is a field shaping multi-well photomultiplier and method for fabrication thereof. The photomultiplier includes a field-shaping multi-well avalanche detector, including a lower insulator, an a-Se photoconductive layer and an upper insulator. The a-Se photoconductive layer is positioned between the lower insulator and the upper insulator. A light interaction region, an avalanche region, and a collection region are provided along a length of the photomultiplier, and the light interaction region and the collection region are positioned on opposite sides of the avalanche region. |
| FILED | Thursday, October 01, 2020 |
| APPL NO | 17/061035 |
| ART UNIT | 2819 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/10 (20130101) H01L 31/20 (20130101) H01L 31/054 (20141201) H01L 31/085 (20130101) H01L 31/107 (20130101) H01L 31/0272 (20130101) Original (OR) Class H01L 31/0376 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11179564 | Ray et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri); Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri); Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Wilson Z. Ray (St. Louis, Missouri); Matthew R. MacEwan (St. Louis, Missouri); Zohny S. Zohny (St. Louis, Missouri); John A. Rogers (Evanston, Illinois) |
| ABSTRACT | A system for stimulating tissue generally comprises a resorbable implant. The resorbable implant includes a substrate, at least one contact, and a transceiver, wherein the substrate, the at least one contact, and the transceiver are resorbable. The system also includes a controller configured to communicate with the transceiver of the resorbable implant and a power supply connected to the controller. The controller delivers power to the resorbable implant from the power supply. The resorbable implant delivers electrical stimulation to tissue when the resorbable implant receives power. |
| FILED | Wednesday, April 25, 2018 |
| APPL NO | 16/608218 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/20 (20130101) A61N 1/205 (20130101) Original (OR) Class A61N 1/375 (20130101) A61N 1/0456 (20130101) A61N 1/0504 (20130101) A61N 1/37217 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180251 | Kang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Hao Kang (Abingdon, Maryland); John W. Gerdes, III (Bel Air, Maryland) |
| ABSTRACT | A method and apparatus for an unmanned aerial system is described herein. An unmanned aerial system capable of being launched from a grenade launcher includes a tubular body that encloses a compartment for a payload and a battery, a motor coupled to the tubular body, a propeller coupled to the motor, and a parachute disposed within the tubular body when the unmanned aerial system is in a stowed configuration and disposed outside of the tubular body when the unmanned aerial system is in a powered flight configuration. |
| FILED | Tuesday, September 04, 2018 |
| APPL NO | 16/120488 |
| ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 39/028 (20130101) Original (OR) Class B64C 2201/08 (20130101) B64C 2201/20 (20130101) B64C 2201/107 (20130101) B64C 2201/165 (20130101) Apparatus for Launching Projectiles or Missiles From Barrels, e.g Cannons; Launchers for Rockets or Torpedoes; Harpoon Guns F41F 1/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180420 | Laskoski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Matthew Laskoski (Springfield, Virginia); Boris Dyatkin (Washington, District of Columbia); Teddy M. Keller (Fairfax Station, Virginia) |
| ABSTRACT | Disclosed is a composition having nanoparticles or particles of a refractory metal, a refractory metal hydride, a refractory metal carbide, a refractory metal nitride, or a refractory metal boride, an organic compound consisting of carbon and hydrogen, and a nitrogenous compound consisting of carbon, nitrogen, and hydrogen. The composition, optionally containing the nitrogenous compound, is milled, cured to form a thermoset, compacted into a geometric shape, and heated in a nitrogen atmosphere at a temperature that forms a nanoparticle composition comprising nanoparticles of metal nitride and optionally metal carbide. The nanoparticles have a uniform distribution of the nitride or carbide. |
| FILED | Wednesday, March 03, 2021 |
| APPL NO | 17/190977 |
| ART UNIT | 1796 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 21/0617 (20130101) C01B 21/0641 (20130101) C01B 21/0682 (20130101) C01B 21/0761 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/64 (20130101) C04B 35/76 (20130101) C04B 35/80 (20130101) Original (OR) Class C04B 35/83 (20130101) C04B 35/515 (20130101) C04B 35/524 (20130101) C04B 35/583 (20130101) C04B 35/584 (20130101) C04B 35/591 (20130101) C04B 35/6261 (20130101) C04B 35/6264 (20130101) C04B 35/58007 (20130101) C04B 35/58014 (20130101) C04B 35/58028 (20130101) C04B 35/58035 (20130101) C04B 2235/46 (20130101) C04B 2235/48 (20130101) C04B 2235/77 (20130101) C04B 2235/80 (20130101) C04B 2235/95 (20130101) C04B 2235/386 (20130101) C04B 2235/404 (20130101) C04B 2235/421 (20130101) C04B 2235/428 (20130101) C04B 2235/604 (20130101) C04B 2235/656 (20130101) C04B 2235/658 (20130101) C04B 2235/761 (20130101) C04B 2235/3817 (20130101) C04B 2235/3856 (20130101) C04B 2235/3873 (20130101) C04B 2235/3886 (20130101) C04B 2235/5248 (20130101) C04B 2235/5454 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180452 | Singhal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CFD RESEARCH CORPORATION (Huntsville, Alabama); THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (Norman, Oklahoma) |
| ASSIGNEE(S) | CFD Research Corporation (Huntsville, Alabama); The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| INVENTOR(S) | Anuj Singhal (Huntsville, Alabama); Robert H. Cichewicz (Norman, Oklahoma); Lin Du (Norman, Oklahoma); JianLan You (Forest Hills, New York); Hanumantha Rao Paritala (Madison, Alabama); Abigail Grace Edwards (Hazel Green, Alabama) |
| ABSTRACT | A method of selectively inhibiting pathogenic microbes includes: providing a compound that is functional as a selective antimicrobial having a structure of Formula 1, or derivative thereof, salt thereof, or stereoisomer thereof, or having any chirality at any chiral center, or tautomer, polymorph, solvate, or combination thereof; and contacting a pathogenic microbe with the compound such that the pathogenic microbe is selectively inhibited; wherein: ring A is a cycloalkyl, heterocycloalkyl, aryl, heteroaryl, or polycycle combination thereof; X is S, SO, or SO2; Y is a linker or bond; Z is CH, CR2, or N; Z1 is C or N to form an imidazopyridine; each Z2, Z3, or Z4 is independently CH, CR2, or N; each Z5 or Z6 is C or CH; each R1, R2, R3 and/or R4 is independently a substituent; m is 0, 1, 2, 3, or 4; and n is zero or a positive integer. |
| FILED | Wednesday, June 17, 2020 |
| APPL NO | 16/904364 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/08 (20130101) A01N 43/38 (20130101) A01N 43/40 (20130101) A01N 43/90 (20130101) A01N 55/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 47/54 (20170801) A61K 47/60 (20170801) A61K 47/545 (20170801) Heterocyclic Compounds C07D 209/30 (20130101) Original (OR) Class C07D 401/12 (20130101) C07D 417/12 (20130101) C07D 471/04 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/1804 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180528 | Bishop et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | George Mason University (Fairfax, Virginia) |
| ASSIGNEE(S) | George Mason University (Fairfax, Virginia) |
| INVENTOR(S) | Barney Bishop (Annandale, Virginia); Monique Van Hoek (Centreville, Virginia); Stephanie Barksdale (Woodbridge, Virginia) |
| ABSTRACT | Peptides are described herein, in particular peptides having antimicrobial properties, as are compositions, articles, and kits comprising such peptides, and methods for using the peptides. |
| FILED | Tuesday, November 26, 2019 |
| APPL NO | 16/696904 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/00 (20180101) Peptides C07K 4/00 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) G01N 33/56911 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180616 | Wiesner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Ulrich B. Wiesner (Ithaca, New York); Yuk Mun Li (Ithaca, New York); Qi Zhang (Ithaca, New York) |
| ABSTRACT | Methods of making blended, isoporous, asymmetric (graded) films (e.g. ultrafiltration membranes) comprising two or more chemically distinct block copolymers and blended, isoporous, asymmetric (graded) films (e.g. ultrafiltration membranes) comprising two or more chemically distinct block copolymers. The generation of blended membranes by mixing two chemically distinct block copolymers in the casting solution demonstrates a pathway to advanced asymmetric block copolymer derived films, which can be used as ultrafiltration membranes, in which different pore surface chemistries and associated functionalities can be integrated into a single membrane via standard membrane fabrication, i.e. without requiring laborious post-fabrication modification steps. The block copolymers may be diblock, triblock and/or multiblock mixes and some block copolymers in the mix may be functionally modified. Triblock copolymers comprising a reactive group (e.g., sulfhydryl group) terminated block and films comprising the triblock copolymers. |
| FILED | Monday, March 09, 2020 |
| APPL NO | 16/813444 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 61/145 (20130101) B01D 67/0013 (20130101) B01D 67/0079 (20130101) B01D 67/0093 (20130101) B01D 69/02 (20130101) B01D 69/14 (20130101) B01D 71/26 (20130101) B01D 71/28 (20130101) B01D 71/40 (20130101) B01D 71/66 (20130101) B01D 71/80 (20130101) B01D 2323/36 (20130101) B01D 2325/04 (20130101) B01D 2325/022 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/20 (20130101) B32B 5/32 (20130101) B32B 2250/02 (20130101) B32B 2250/22 (20130101) B32B 2266/025 (20130101) B32B 2266/102 (20161101) B32B 2266/0228 (20130101) B32B 2270/00 (20130101) B32B 2307/73 (20130101) B32B 2307/726 (20130101) B32B 2307/728 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 81/024 (20130101) Original (OR) Class Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/28 (20130101) C08J 9/0061 (20130101) C08J 9/365 (20130101) C08J 2201/0502 (20130101) C08J 2201/0542 (20130101) C08J 2205/042 (20130101) C08J 2353/02 (20130101) C08J 2453/02 (20130101) Compositions of Macromolecular Compounds C08L 53/00 (20130101) C08L 53/00 (20130101) C08L 53/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180696 | Boyd et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Darryl A. Boyd (Alexandria, Virginia); Michael H. Stewart (Springfield, Virginia); Kimihiro Susumu (Alexandria, Virginia); Eunkeu Oh (Alexandria, Virginia); James P. Wissman (Hyattsville, Maryland) |
| ABSTRACT | This disclosure concerns a method of making a ligand for Quantum Dot functionalization, a method of making a functionalized Quantum Dot (QD) with a ligand, and a method of making a transparent luminescent quantum dot thiol-yne nanocomposite with tailorable optical, thermal, and mechanical properties. The prepolymer solution and functionalized Quantum Dot can be used in additive manufacturing. |
| FILED | Friday, October 05, 2018 |
| APPL NO | 16/153357 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 339/04 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/02 (20130101) C09K 11/886 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180762 | Lieberman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Judy Lieberman (Brookline, Massachusetts); Adi Gilboa-Geffen (Brookline, Massachusetts); Lee Adam Wheeler (Boston, Massachusetts) |
| ABSTRACT | Described herein are methods and compositions relating to the treatment of cancer, e.g., breast cancer, using, e.g., aptamer-siRNA chimera molecules. |
| FILED | Friday, May 10, 2019 |
| APPL NO | 16/409081 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) A61K 2039/5152 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/00 (20130101) Peptides C07K 14/705 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/115 (20130101) Original (OR) Class C12N 15/1137 (20130101) C12N 2310/14 (20130101) C12N 2310/16 (20130101) C12N 2310/322 (20130101) C12N 2310/3519 (20130101) C12N 2310/3533 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11181006 | Smoke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | HONEYWELL INTERNATIONAL INC. (Charlotte, North Carolina) |
| INVENTOR(S) | Jason Smoke (Phoenix, Arizona); Kent L. Kime (Phoenix, Arizona); Blake Petersen (Scottsdale, Arizona); Luke Zurmehly (Phoenix, Arizona) |
| ABSTRACT | A shroud assembly for a gas turbine engine includes a plurality of shroud segments that are attached to a shroud support with an inter-segment joint defined between shroud segments. The shroud assembly also includes a cooling flow path cooperatively defined by the shroud support and the first shroud segment. The cooling flow path includes an internal cooling passage within the shroud segments. The cooling flow path includes an outlet chamber configured to receive flow from the internal cooling passage. The shroud assembly additionally includes a seal arrangement that extends across the inter-segment joint. The seal arrangement, the first shroud segment, and the second shroud segment cooperatively define a seal chamber that is enclosed. |
| FILED | Thursday, March 26, 2020 |
| APPL NO | 16/831045 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/04 (20130101) F01D 11/005 (20130101) F01D 11/08 (20130101) Original (OR) Class F01D 11/122 (20130101) F01D 25/12 (20130101) F01D 25/246 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/11 (20130101) F05D 2240/55 (20130101) F05D 2240/56 (20130101) F05D 2260/201 (20130101) F05D 2260/204 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11181046 | Brooks et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Florida Turbine Technologies, Inc. (Jupiter, Florida) |
| ASSIGNEE(S) | FLORIDA TURBINE TECHNOLOGIES, INC. (Jupiter, Florida) |
| INVENTOR(S) | Stephen M Brooks (Jupiter, Florida); Alex Pinera (Jupiter, Florida) |
| ABSTRACT | A gas turbine engine in which a long length-to-diameter (L/D) flexible shaft is used to connect two high speed shafts in order to tolerate misalignment. In order to reduce the overall system length, a smaller diameter flexible shaft is contained within but not in contact with a larger diameter primary turbomachinery shaft such that the smaller flexible shaft adjoins to the primary shaft aft of the primary shaft bearing. This design reduces a length of the overall system and reduces additional cost associated with a flex bellows or spline. |
| FILED | Tuesday, September 10, 2019 |
| APPL NO | 16/566434 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/36 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/62 (20130101) Couplings for Transmitting Rotation; Clutches; Brakes F16D 3/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11181354 | Meyer |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Charles Meyer (Gulf Breeze, Florida) |
| ABSTRACT | A countersink go/no-go gauge is configured to aid a determination of whether a countersink aperture for a rivet is formed to a desired depth. The countersink go/no-go gauge includes a head having a depth defined between a top surface and a bottom surface and a shaft extending from the top surface of the head. The depth of the head is substantially equal to a desired depth of a countersink aperture. In some embodiments the go/no-go gauge includes tolerance features to provide a range for an acceptable countersink depth. |
| FILED | Friday, March 05, 2021 |
| APPL NO | 17/192971 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Forging; Hammering; Pressing Metal; Riveting; Forge Furnaces B21J 15/02 (20130101) B21J 15/38 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 3/50 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11181460 | Wilke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Combat Capabilities Development Command, Chemical Biological Center (Apg, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Douglas E Wilke (Joppa, Maryland); Terrence G D'Onofrio (Bel Air, Maryland); Christopher B. Steinbach (Phoenix, Maryland) |
| ABSTRACT | A test cell may include a base frame including a test slot; a pressure-generating insert positioned on a pedestal within the test slot; an impermeable protective layer in contact with the base frame; a sorbent layer positioned between the pressure-generating insert and the impermeable protective layer; a complex protective material swatch in contact with the sorbent layer, the complex protective material swatch having a contaminant applied thereon; a locking frame in contact with the impermeable protective layer, wherein the locking frame secures the impermeable protective layer to the base frame; a sealing gasket in contact with at least the locking frame and the complex protective material swatch; a gasket compression frame in contact with the sealing gasket; a cover in contact with the stability plate; and weights in contact with the cover. The test cell may be included in methods for measuring permeation of contaminants through complex protective material swatches. |
| FILED | Wednesday, June 17, 2020 |
| APPL NO | 16/903729 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 11/08 (20130101) G01N 15/0806 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11181580 | Zobel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| INVENTOR(S) | Matthew S. Zobel (Mammoth Lakes, California); Brian R. Gonzales (Hermosa Beach, California); Jose A. Becerra (Downey, California); Javier Munoz (Hawthorne, California) |
| ABSTRACT | A non-volatile computer data storage programming system includes a scan chain modification configured to receive a default model defining a scan chain of an industry standardized device. A controller is in signal communication with the scan chain modification system, and is configured to program an industry standardized device. A non-volatile computer data storage device is configured to receive data from the industry standardized device. The scan chain modification system modifies the default model to generate a new model including a reduced scan chain, and the controller programs the industry standardized device based on the new model such that the industry standardized device is programmed with the reduced scan chain. |
| FILED | Thursday, October 03, 2019 |
| APPL NO | 16/592053 |
| ART UNIT | 2112 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/3177 (20130101) G01R 31/318572 (20130101) G01R 31/318597 (20130101) Original (OR) Class Static Stores G11C 16/04 (20130101) G11C 16/102 (20130101) G11C 29/32 (20130101) G11C 2029/3202 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11181630 | Weiner |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Ian Weiner (Arlington, Massachusetts) |
| ABSTRACT | A high-throughput communications channel is encoded using transmit waveforms which satisfy a variety of technical constraints deemed desirable for effective radar operations and signal processing. This enables new cooperative spectrum sharing modalities for radar and communications systems. |
| FILED | Friday, April 17, 2020 |
| APPL NO | 16/852005 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/42 (20130101) G01S 13/53 (20130101) Original (OR) Class G01S 13/505 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11182126 | Barillas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Ender Barillas (Orlando, Florida); Brian Filarsky (Tucson, Arizona) |
| ABSTRACT | Computationally efficient mixed precision floating point waveform generation takes advantage of the high-speed generation of waveforms with single-precision floating point numbers while reducing the generally unacceptable loss of precision of pure single-precision floating point to generate any waveform that repeats in 2π. This approaches computes a reference phase in double precision as the modulus of the phase with 2π and then computes offsets to that value in single precision. The double precision reference phase is recomputed as needed depending on how quickly the phase grows and how large a machine epsilon is desired. |
| FILED | Tuesday, June 25, 2019 |
| APPL NO | 16/451867 |
| ART UNIT | 2182 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 7/57 (20130101) G06F 7/60 (20130101) G06F 7/483 (20130101) Original (OR) Class G06F 9/545 (20130101) G06F 9/3001 (20130101) G06F 9/3887 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11182415 | Srirangamsridharan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Shreeranjani Srirangamsridharan (White Plains, New York); Raghu Kiran Ganti (Elmsford, New York); Mudhakar Srivatsa (White Plains, New York); Yeon-Sup Lim (White Plains, New York) |
| ABSTRACT | Embodiments of the invention include method, systems and computer program products for document vectorization. Aspects include receiving, by a processor, a plurality of documents each having a plurality of word. The processor utilizing a vector embeddings engine generates a vector to represent each of the plurality of words in the plurality of documents. An image representation for each document in the plurality of documents is created and a word probability for each of the plurality of words in the plurality of documents is generated. A position for each word probability is determined in the image based on the vector associated with each word and a compression operation on the images is performed to produce a compact representation for the plurality of documents. |
| FILED | Wednesday, July 11, 2018 |
| APPL NO | 16/032764 |
| ART UNIT | 2159 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/93 (20190101) G06F 16/313 (20190101) G06F 16/3347 (20190101) Original (OR) Class G06F 40/20 (20200101) G06F 40/40 (20200101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00456 (20130101) G06K 9/00463 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11182674 | Bose et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Pradip Bose (Yorktown Heights, New York); Alper Buyuktosunoglu (White Plains, New York); Augusto J. Vega (Mount Vernon, New York) |
| ABSTRACT | Embodiments of the present invention include a system, computer-implemented method, and a computer program product. A non-limiting example of the method includes a processor utilizing a model having a plurality of parameters. The processor compares a current value of a model parameter to a prior value of the model parameter. Based at least in part on comparing the current value of the model parameter to the prior value of the model parameter, a determination is made that the model being utilized by the processor has changed. The current value of the model parameter is transmitted by the processor. |
| FILED | Friday, March 17, 2017 |
| APPL NO | 15/461643 |
| ART UNIT | 2121 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/082 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11182888 | McCall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SPECTRAL MD, INC. (Dallas, Texas) |
| ASSIGNEE(S) | SPECTRAL MD, INC. (Dallas, Texas) |
| INVENTOR(S) | Brian McCall (Dallas, Texas); Wensheng Fan (Plano, Texas); Jason Dwight (Dallas, Texas); Zhicun Gao (Plano, Texas); Jeffrey E. Thatcher (Irving, Texas); John Michael DiMaio (Dallas, Texas) |
| ABSTRACT | Generally described, one or more aspects of the present application correspond to systems and techniques for spectral imaging using a multi-aperture system with curved multi-bandpass filters positioned over each aperture. The present disclosure further relates to techniques for implementing spectral unmixing and image registration to generate a spectral datacube using image information received from such imaging systems. Aspects of the present disclosure relate to using such a datacube to analyze the imaged object, for example to analyze tissue in a clinical setting, perform biometric recognition, or perform materials analysis. |
| FILED | Friday, August 07, 2020 |
| APPL NO | 16/988064 |
| ART UNIT | 2481 — Recording and Compression |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/50 (20130101) Original (OR) Class G06T 7/0012 (20130101) G06T 7/33 (20170101) G06T 7/55 (20170101) G06T 7/62 (20170101) G06T 2207/10036 (20130101) G06T 2207/10144 (20130101) G06T 2207/20221 (20130101) Pictorial Communication, e.g Television H04N 5/265 (20130101) H04N 5/2254 (20130101) H04N 5/2256 (20130101) H04N 5/2356 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11183227 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Jian-Ping Wang (Shoreview, Minnesota); Delin Zhang (Saint Paul, Minnesota); Protyush Sahu (Minneapolis, Minnesota) |
| ABSTRACT | A magnetic device may include a layer stack. The layer stack may include a first ferromagnetic layer; a spacer layer on the first ferromagnetic layer; a second ferromagnetic layer on the spacer layer; and a dielectric barrier layer on the second ferromagnetic layer. In some examples, the layer stack may also include an additional ferromagnetic layer and an additional spacer layer. The magnetic device also may include a voltage source configured to apply a bias voltage across the layer stack to cause switching of a magnetic orientation of the second ferromagnetic layer without application of an external magnetic field. |
| FILED | Wednesday, April 29, 2020 |
| APPL NO | 16/861869 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 11/18 (20130101) G11C 11/161 (20130101) Original (OR) Class G11C 11/1673 (20130101) G11C 11/1675 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/222 (20130101) H01L 43/04 (20130101) H01L 43/06 (20130101) H01L 43/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11183638 | Mei et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Jianguo Mei (West Lafayette, Indiana); Aristide Gumyusenge (West Lafayette, Indiana) |
| ABSTRACT | A composition for use as an electronic material. The composition contains at least one organic semiconducting material, and at least one electrically insulating polymer forming a semiconducting blend wherein the insulating polymer acts as a matrix for the organic semiconducting material resulting in an interpenetrating morphology of the polymer and the semiconductor material. The variation of charge carrier mobility with temperature in the semiconducting blend is less than 20 percent in a temperature range. A method of making a film of an electronic material. The method includes dissolving at least one organic semiconducting material and at least one insulating polymer into an organic solvent in a pre-determined ratio resulting in a semiconducting blend, depositing the blend onto a substrate to form a film comprising an interpenetrating morphology of the at least one insulating polymer and the at least one organic semiconductor material. |
| FILED | Friday, May 24, 2019 |
| APPL NO | 16/422665 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/004 (20130101) H01L 51/0007 (20130101) H01L 51/0028 (20130101) H01L 51/0035 (20130101) H01L 51/0036 (20130101) Original (OR) Class H01L 51/0042 (20130101) H01L 51/0043 (20130101) H01L 51/0545 (20130101) H01L 51/0566 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11183713 | Rastegar |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Omnitek Partners LLC (Ronkonkoma, New York) |
| ASSIGNEE(S) | OMNITEK PARTNERS, LLC (Ronkonkoma, New York) |
| INVENTOR(S) | Jahangir S Rastegar (Stony Brook, New York) |
| ABSTRACT | A method for fabricating a Lithium-Ion reserve battery, the method including: assembling an operational Lithium-ion battery having an anode, cathode, separator membrane between the anode and cathode and an electrolyte; charging the assembled Lithium-ion battery; disassembling the Lithium-ion battery by separating the anode, cathode and separator membrane and removing the electrolyte; rinsing and drying the disassembled cathode and anode; reassembling the rinsed and dried cathode and anode with a new separator membrane between the anode and cathode and without the electrolyte to provide the Lithium-Ion reserve battery; and discharging the Lithium-Ion reserve battery. |
| FILED | Wednesday, August 07, 2019 |
| APPL NO | 16/535000 |
| ART UNIT | 1728 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/0447 (20130101) H01M 10/446 (20130101) H01M 10/0525 (20130101) H01M 10/0585 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11183774 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The MITRE Corporation (McLean, Virginia) |
| ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
| INVENTOR(S) | Jerry T. W. Kim (Fairfax, Virginia); Behrooz Fakhari (North Potomac, Maryland) |
| ABSTRACT | A transportable, resilient, high frequency system with a compact footprint is provided. The system may include a plurality of antenna elements arranged around a circle. A circular array provides a resilient radiation pattern that does not change based on the number of antennas in the array and is tolerant of errors in antenna placement. The gain of the system may be increased by increasing the number of antenna elements in the array to compensate for reduced efficiency of antenna elements having a radiating element with a length of less than half the wavelength of an operating frequency of the array. |
| FILED | Friday, May 31, 2019 |
| APPL NO | 16/428327 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 3/28 (20130101) H01Q 21/20 (20130101) Original (OR) Class H01Q 21/26 (20130101) H01Q 21/293 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11184006 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Chen Wang (New Haven, Connecticut); Yvonne Gao (New Haven, Connecticut); Luigi Frunzio (North Haven, Connecticut); Michel Devoret (New Haven, Connecticut); Robert J. Schoelkopf, III (Madison, Connecticut) |
| ABSTRACT | According to some aspects, a method is provided of operating a system that includes a multi-level quantum system dispersively coupled to a first quantum mechanical oscillator and dispersively coupled to a second quantum mechanical oscillator, the method comprising applying a first drive waveform to the multi-level quantum system, applying one or more second drive waveforms to the first quantum mechanical oscillator, and applying one or more third drive waveforms to the second quantum mechanical oscillator. |
| FILED | Friday, January 13, 2017 |
| APPL NO | 16/068405 |
| ART UNIT | 2849 — Electrical Circuits and Systems |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 5/1847 (20130101) Pulse Technique H03K 19/195 (20130101) Original (OR) Class Transmission H04B 10/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11184016 | Hong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brian Daffern Hong (Sierra Madre, California) |
| ASSIGNEE(S) | Brian Daffern Hong (Sierra Madre, California) |
| INVENTOR(S) | Brian Daffern Hong (Sierra Madre, California); Seyed Ali Hajimiri (Pasadena, California) |
| ABSTRACT | The present disclosure includes a frequency divider circuit that includes a superharmonically injection-locked ring oscillator, injection circuitry, and various switches. The input can include a collection of signal components at different phases that are all at the same, but changeable, frequency. The divider's division ratio can be changed during the divider's operation by, for example, utilizing one or more switches to change: the number of stages in the ring oscillator, and/or which stage(s) of the ring oscillator are injected into by which input signal components. |
| FILED | Monday, January 11, 2021 |
| APPL NO | 17/145886 |
| ART UNIT | 2849 — Electrical Circuits and Systems |
| CURRENT CPC | Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 5/1228 (20130101) Pulse Technique H03K 3/0322 (20130101) Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses H03L 7/24 (20130101) Original (OR) Class H03L 7/183 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11184221 | Alvarez-Icaza Rivera et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Rodrigo Alvarez-Icaza Rivera (Mountain View, California); John V. Arthur (San Jose, California); Andrew S. Cassidy (Austin, Texas); Bryan L. Jackson (Fremont, California); Paul A. Merolla (Palo Alto, California); Dharmendra S. Modha (San Jose, California); Jun Sawada (Austin, Texas) |
| ABSTRACT | Embodiments of the invention provide a neurosynaptic network circuit comprising multiple neurosynaptic devices including a plurality of neurosynaptic core circuits for processing one or more data packets. The neurosynaptic devices further include a routing system for routing the data packets between the core circuits. At least one of the neurosynaptic devices is faulty. The routing system is configured for selectively bypassing each faulty neurosynaptic device when processing and routing the data packets. |
| FILED | Friday, August 16, 2019 |
| APPL NO | 16/543304 |
| ART UNIT | 2465 — Multiplex and VoIP |
| CURRENT CPC | Electric Digital Data Processing G06F 11/00 (20130101) G06F 11/20 (20130101) G06F 11/0724 (20130101) G06F 11/0793 (20130101) Computer Systems Based on Specific Computational Models G06N 3/049 (20130101) G06N 3/063 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 41/0659 (20130101) H04L 41/0668 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11184374 | Shu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Xiaokui Shu (Ossining, New York); Zhongshu Gu (Ridgewood, New Jersey); Heqing Huang (Mahweh, New Jersey); Marc Philippe Stoecklin (White Plains, New York); Jialong Zhang (White Plains, New York) |
| ABSTRACT | An automated method for cyberattack detection and prevention in an endpoint. The technique monitors and protects the endpoint by recording inter-process events, creating an inter-process activity graph based on the recorded inter-process events, matching the inter-process activity (as represented in the activity graph) against known malicious or suspicious behavior (as embodied in a set of one or more pattern graphs), and performing a post-detection operation in response to a match between an inter-process activity and a known malicious or suspicious behavior pattern. Preferably, matching involves matching a subgraph in the activity graph with a known malicious or suspicious behavior pattern as represented in the pattern graph. During this processing, preferably both direct and indirect inter-process activities at the endpoint (or across a set of endpoints) are compared to the known behavior patterns. The approach herein provides for systematic modeling of inter-process behaviors for characterizing malicious or suspicious patterns among processes. |
| FILED | Friday, October 12, 2018 |
| APPL NO | 16/158798 |
| ART UNIT | 2432 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 16/951 (20190101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/20 (20130101) H04L 63/1416 (20130101) H04L 63/1425 (20130101) Original (OR) Class H04L 63/1433 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11184564 | Genov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (Toronto, Canada) |
| ASSIGNEE(S) | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (Toronto, Canada) |
| INVENTOR(S) | Roman Genov (Toronto, Canada); Kiriakos Neoklis Kutulakos (Toronto, Canada); Navid Sarhangnejad (Toronto, Canada); Nikola Katic (Toronto, Canada); Mian Wei (Mississauga, Canada) |
| ABSTRACT | There is provided a method and system for pixel-wise imaging of a scene. The method including: receiving a pixel-wise pattern, the pixel-wise pattern including a masking value for each pixel in an array of pixels of an image sensor; producing an electronic signal at each pixel when such pixel is exposed to light received from the scene; and directing the electronic signal at each pixel to one or more collection nodes associated with such pixel based on the respective masking value, the one or more collection nodes each capable of integrating the received electronic signal. |
| FILED | Thursday, December 20, 2018 |
| APPL NO | 16/226808 |
| ART UNIT | 2697 — Selective Visual Display Systems |
| CURRENT CPC | Pictorial Communication, e.g Television H04N 5/3535 (20130101) Original (OR) Class H04N 13/254 (20180501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11184783 | Melodia et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | NORTHEASTERN UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Tommaso Melodia (Newton, Massachusetts); Francesco Restuccia (Boston, Massachusetts); Salvatore D'Oro (Allston, Massachusetts) |
| ABSTRACT | A communications system provides for accurate fingerprinting of devices across a communications channel. A transmitter device modifies a physical layer signal prior to transmission as a function of signal modification parameters. A receiver device classifies a received physical layer signal and to outputs a classification indicator and a score. The receiver further analyzes the classification indicator and the score to produce an updated set of signal modification parameters provides the parameters to the transmitter device. The transmitter device, in turn, updates its signal modification parameters accordingly, thereby generating subsequent communications that more clearly indicate a fingerprint of the transmitter device. |
| FILED | Friday, March 27, 2020 |
| APPL NO | 16/832741 |
| ART UNIT | 2412 — Multiplex and VoIP |
| CURRENT CPC | Wireless Communication Networks H04W 24/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11184975 | Charalambides et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Alexandros Charalambides (Pittsburgh, Pennsylvania); Carmel Majidi (Pittsburgh, Pennsylvania) |
| ABSTRACT | According to one embodiment is a flexible circuit comprising a flexible base, a conductive polymer supported by the base, and an integrated circuit component having an elongated electrical contact, wherein the elongated electrical contact penetrates into the conductive polymer, thereby providing a robust electrical connection. According to methods of certain embodiments, the flexible circuit is manufactured using a molding process, where a conductive polymer is deposited into recesses in a mold, integrated circuit components are placed in contact with the conductive polymer, and a flexible polymer base is poured over the mold prior to curing. In an alternative embodiment, a multiple-layer flexible circuit is manufacturing using a plurality of molds. |
| FILED | Tuesday, February 06, 2018 |
| APPL NO | 16/483841 |
| ART UNIT | 2848 — Electrical Circuits and Systems |
| CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/09 (20130101) H05K 1/185 (20130101) H05K 1/0277 (20130101) Original (OR) Class H05K 3/0014 (20130101) H05K 3/34 (20130101) H05K 3/107 (20130101) H05K 3/4038 (20130101) H05K 3/4644 (20130101) H05K 2201/0215 (20130101) H05K 2201/0329 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11178832 | Kaeppler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin); THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| INVENTOR(S) | Shawn Michael Kaeppler (Oregon, Wisconsin); Hannah Marie Schneider (Cologne, Minnesota); Jonathan Paul Lynch (Boalsburg, Pennsylvania); Malcolm John Bennett (Tollerton, United Kingdom) |
| ABSTRACT | The present invention relates to crop breeding. More particularly, the present invention relates to targeted modification of root angle to enhance abiotic stress tolerance in maize. In one aspect, the invention provides recombinant maize exhibiting increased root angle by decreasing the function of the maize ZMCIPK15 gene. Methods of making the recombinant maize and various methods of plant selection and breeding are further provided. |
| FILED | Friday, November 09, 2018 |
| APPL NO | 16/185739 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 1/04 (20130101) A01H 1/06 (20130101) Original (OR) Class A01H 5/10 (20130101) A01H 6/4684 (20180501) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/102 (20130101) C12N 15/1024 (20130101) C12N 15/8242 (20130101) C12N 15/8262 (20130101) C12N 15/8273 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6827 (20130101) C12Q 1/6895 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11179027 | Rentschler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a Body Corporate (Denver, Colorado) |
| INVENTOR(S) | Mark Rentschler (Boulder, Colorado); Levin J. Sliker (Boulder, Colorado); Madalyn D. Kern (Broomfield, Colorado); Joseph Micah Prendergast (Boulder, Colorado); William S. Smith (Boulder, Colorado); Kyle Galbraith (Santa Rosa, California); James Depoy (Parker, Colorado); Karina Rose Laguardia (Boulder, Colorado); Andrew Patrick Gloor (Salida, Colorado); Derek Sawyer (Colorado Springs, Colorado) |
| ABSTRACT | The invention provides devices that can be used for any endoscopy procedure. In certain embodiments, the devices of the invention reduce the occurrence of looping in the most difficult segment of the colon to navigate—the splenic flexure. In other embodiments, the devices of the invention make colonoscopies more comfortable for patients and reduce the risk of damage to the colon. In yet other embodiments, the devices of the invention comprise a supportive, friction-reducing device that can be attached to the tip of existing endoscopes to help the scope advance better through the colon and intestinal tract. |
| FILED | Monday, December 05, 2016 |
| APPL NO | 15/780493 |
| ART UNIT | 3795 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/31 (20130101) A61B 1/00082 (20130101) A61B 1/00135 (20130101) A61B 1/00154 (20130101) Original (OR) Class Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/1011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11179050 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan); UNIVERSITY OF MARYLAND (College Park, Maryland) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan); University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Jiankun Liu (East Lansing, Michigan); Mohsen Moslehpour (Sunnyvale, California); Jin-Oh Hahn (Rockville, Maryland); Ramakrishna Mukkamala (Okemos, Michigan) |
| ABSTRACT | Most automatic cuff blood pressure (BP) measurement devices are based on oscillometry. These devices estimate BP from the envelopes of the cuff pressure oscillations using fixed ratios. The values of the fixed ratios represent population averages, so the devices may be accurate only in subjects with normal BP levels. A patient-specific oscillometric BP measurement method was developed. The idea was to represent the cuff pressure oscillation envelopes with a physiologic model and then estimate the patient-specific parameters of the model, which includes BP levels, by optimally fitting it to the envelopes. |
| FILED | Friday, September 09, 2016 |
| APPL NO | 15/758401 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/02 (20130101) A61B 5/021 (20130101) A61B 5/022 (20130101) A61B 5/02225 (20130101) Original (OR) Class A61B 2562/0247 (20130101) Electric Digital Data Processing G06F 2111/10 (20200101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11179060 | Odame et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | Kofi Odame (Hanover, New Hampshire); Justice Amoh (Hanover, New Hampshire) |
| ABSTRACT | A system adapted to assisting patients manage asthma includes a wearable sensor for detection of asthma symptoms and inhaler use, having a microphone capable of generating an electrical signal indicative of asthma symptoms or inhaler use; a processor with firmware adapted to process the electrical signal to determine potential asthma symptoms and inhaler use; and store the electrical signal in the memory when the electrical signal potentially corresponds asthma symptoms or inhaler use. In particular embodiments, the system includes an electronic asthma diary including detected asthma symptoms and detected inhaler usage, both with timestamps, and a prescribed treatment protocol. Protocol firmware processes detected asthma symptoms an inhaler usage recorded in the asthma diary to determine if asthma is controlled, and if asthma is not determined controlled determines if a treatment change is authorized; if treatment change is authorized the treatment change is displayed in human-readable form. |
| FILED | Thursday, July 07, 2016 |
| APPL NO | 15/742510 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0024 (20130101) A61B 5/087 (20130101) A61B 5/486 (20130101) A61B 5/725 (20130101) A61B 5/0823 (20130101) Original (OR) Class A61B 5/6822 (20130101) A61B 5/6823 (20130101) A61B 5/7207 (20130101) A61B 5/7267 (20130101) A61B 7/003 (20130101) A61B 2562/0204 (20130101) A61B 2562/0219 (20130101) A61B 2562/0247 (20130101) A61B 2562/0261 (20130101) Electric Digital Data Processing G06F 16/22 (20190101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 20/10 (20180101) G16H 40/67 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11179682 | Yildiz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Bilge Yildiz (Cambridge, Massachusetts); Nikolai Tsvetkov (Cambridge, Massachusetts); Qiyang Lu (Cambridge, Massachusetts) |
| ABSTRACT | A method and a composition to stabilize the surface cation chemistry of the perovskite or related oxides, and thus, to minimize or completely avoid the detrimental segregation and phase separation of dopant cations at the surface can include modifying the surface with more oxidizable metal cations and/or more oxidizable metal oxides, thereby reducing the oxygen vacancy concentration at the very surface. |
| FILED | Wednesday, March 30, 2016 |
| APPL NO | 15/563535 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/228 (20130101) B01D 71/024 (20130101) Original (OR) Class Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/83 (20130101) B01J 2523/00 (20130101) B01J 2523/00 (20130101) B01J 2523/24 (20130101) B01J 2523/24 (20130101) B01J 2523/842 (20130101) B01J 2523/842 (20130101) B01J 2523/845 (20130101) B01J 2523/845 (20130101) B01J 2523/3706 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/34 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 11/0773 (20210101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/08 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/9025 (20130101) H01M 4/9033 (20130101) H01M 2008/1293 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11179717 | Lopez |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Gabriel P. Lopez (Durham, North Carolina) |
| ABSTRACT | A kit for detection of an analyte of interest in a liquid sample, and methods of using, are provided. The kit may include a pipette and a disposable pipette tip configured to engage the pipette. The pipette tip may define an acoustic channel configured for allowing flow-through of a liquid. The kit may also include a vibratory device in communication with the acoustic channel and configured for imparting a vibratory force thereto. The impartation of the vibratory force may create standing acoustic waves, thereby separating any negative acoustic contrast particles (NACPs) from the remaining contents of the liquid sample. The NACPs may capable of biospecific recognition of the analyte of interest, thereby separating the analytes of interest, which can then be collected or analyzed accordingly. |
| FILED | Tuesday, July 03, 2018 |
| APPL NO | 16/026581 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/0275 (20130101) Original (OR) Class B01L 2200/0652 (20130101) B01L 2200/0668 (20130101) B01L 2300/0832 (20130101) B01L 2300/0858 (20130101) B01L 2400/0433 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4077 (20130101) G01N 2001/4094 (20130101) G01N 2015/1006 (20130101) G01N 2035/1048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11179721 | Butler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Jason E. Butler (Gainesville, Florida); Anthony J. Ladd (Gainesville, Florida); Mert Arca (Hillsboro, Oregon) |
| ABSTRACT | Provided herein are microfluidic devices that can be configured to generate an electrophoretic flow that is in opposition to a fluid flow through a microcapillary of a microfluidic device provided herein. Also provided herein are methods that include adding an amount of particle to the inlet area of a microfluidic device as provided herein, generating a first fluid flow through a microcapillary of a microfluidic device provided herein; and applying a uniform electric field to the microfluidic device, where the uniform electric field generates an electrophoretic flow that is in opposition to the fluid flow. |
| FILED | Thursday, July 21, 2016 |
| APPL NO | 15/746319 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502715 (20130101) B01L 3/502761 (20130101) Original (OR) Class B01L 2200/0668 (20130101) B01L 2300/16 (20130101) B01L 2300/0838 (20130101) B01L 2400/0421 (20130101) B01L 2400/0487 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6816 (20130101) C12Q 1/6816 (20130101) C12Q 2565/125 (20130101) C12Q 2565/629 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4077 (20130101) G01N 27/447 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11179884 | Guimbretiere et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Francois Guimbretiere (Ithaca, New York); Huaishu Peng (Ithaca, New York); Stephen Robert Marschner (Ithaca, New York); Rundong Wu (Ithaca, New York) |
| ABSTRACT | Systems and methods are provided for incremental 3D printing, wherein wireframes are generated and printed (scheduled for print) during the design process. In another aspect, systems and methods are provided for printing arbitrary meshes. A 3D printer system is described having, for example, five degree-of-freedom (5DOF). The 5DOF printer may be used to perform any of the methods described herein and combinations of the methods. |
| FILED | Friday, April 14, 2017 |
| APPL NO | 16/093885 |
| ART UNIT | 2117 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/118 (20170801) B29C 64/141 (20170801) Original (OR) Class B29C 64/314 (20170801) B29C 64/321 (20170801) B29C 64/393 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 15/02 (20130101) Electric Digital Data Processing G06F 30/17 (20200101) Image Data Processing or Generation, in General G06T 17/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180481 | Arora et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York) |
| ASSIGNEE(S) | NEW YORK UNIVERSITY (New York, New York) |
| INVENTOR(S) | Paramjit S. Arora (Cold Spring Harbor, New York); Brooke Bullock Lao (Leesville, South Carolina); Danielle Guarracino (Princeton, New Jersey); Richard Bonneau (New York, New York); Kevin Drew (Austin, Texas) |
| ABSTRACT | The present invention relates to oligooxopiperazines for modulating the p53-Mdm2 interaction. Exemplary oligooxopiperazines include those of Formula IA, Formula IB, and Formula IC below (wherein the various substituents are as defined herein). Methods of using the oligooxopiperazines are also disclosed. |
| FILED | Wednesday, April 15, 2015 |
| APPL NO | 15/304490 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 241/08 (20130101) C07D 403/06 (20130101) Original (OR) Class C07D 403/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180627 | Hess et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Boulder, Colorado) |
| INVENTOR(S) | Andrew J. Hess (Louisville, Colorado); Qingkun Liu (Boulder, Colorado); Ivan I. Smalyukh (Boulder, Colorado) |
| ABSTRACT | Disclosed are cellulose-based flexible gels containing cellulose nanorods, ribbons, fibers, and the like, and cellulose-enabled inorganic or polymeric composites, wherein the gels have tunable optical, heat transfer, and stiffness properties. The disclosed gels are in the form of hydrogels, organogels, liquid-crystal (LC) gels, and aerogels, depending on the solvents in the gels. |
| FILED | Thursday, January 11, 2018 |
| APPL NO | 15/868714 |
| ART UNIT | 1783 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/28 (20130101) C08J 9/35 (20130101) Original (OR) Class C08J 9/0061 (20130101) C08J 2205/02 (20130101) C08J 2205/06 (20130101) C08J 2205/022 (20130101) C08J 2205/024 (20130101) C08J 2205/026 (20130101) C08J 2207/00 (20130101) C08J 2301/02 (20130101) C08J 2383/04 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 5/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180651 | Bates et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Frank S. Bates (St. Louis Park, Minnesota); Lorraine Francis (Minnetonka, Minnesota); Tuoqi Li (Freeport, Texas) |
| ABSTRACT | Embodiments are directed to compositions comprising (i) amphiphilic block copolymer, (ii) resin material; and amine modified graphene oxide; where the composition shows a synergic effect in critical strain energy release rate (Glc) value versus predicted value calculated by adding (i) the Glc value for neat resin material, plus (ii) the difference in Glc found when adding the amphiphilic block copolymer to the resin material versus the neat resin material, plus (iii) the difference in Glc found when adding the amine modified graphene oxide to the resin material versus the neat resin material. |
| FILED | Tuesday, September 05, 2017 |
| APPL NO | 16/331025 |
| ART UNIT | 1768 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/194 (20170801) C01B 32/198 (20170801) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/212 (20130101) C08J 2363/00 (20130101) C08J 2471/02 (20130101) Compositions of Macromolecular Compounds C08L 63/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180743 | Doudna et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jennifer A. Doudna (Berkeley, California); David Burstein (Berkeley, California); Janice S. Chen (Berkeley, California); Lucas B. Harrington (Berkeley, California); David Paez-Espino (Walnut Creek, California); Jillian F. Banfield (Berkeley, California) |
| ABSTRACT | Provided are compositions and methods that include one or more of: (1) a “CasZ” protein (also referred to as a CasZ polypeptide), a nucleic acid encoding the CasZ protein, and/or a modified host cell comprising the CasZ protein (and/or a nucleic acid encoding the same); (2) a CasZ guide RNA that binds to and provides sequence specificity to the CasZ protein, a nucleic acid encoding the CasZ guide RNA, and/or a modified host cell comprising the CasZ guide RNA (and/or a nucleic acid encoding the same); and (3) a CasZ transactivating noncoding RNA (trancRNA) (referred to herein as a “CasZ trancRNA”), a nucleic acid encoding the CasZ trancRNA, and/or a modified host cell comprising the CasZ trancRNA (and/or a nucleic acid encoding the same). |
| FILED | Wednesday, February 12, 2020 |
| APPL NO | 16/789049 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 2319/09 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 15/11 (20130101) C12N 15/113 (20130101) C12N 2310/20 (20170501) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180841 | Hosek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Persimmon Technologies, Corp. (Wakefield, Massachusetts) |
| ASSIGNEE(S) | Persimmon Technologies Corporation (Wakefield, Massachusetts) |
| INVENTOR(S) | Martin Hosek (Lowell, Massachusetts); Sripati Sah (Wakefield, Massachusetts); Jayaraman Krishnasamy (Boxborough, Massachusetts) |
| ABSTRACT | A soft magnetic material comprises a plurality of iron-containing particles and an insulating layer on the iron-containing particles, the insulating layer comprising an oxide. The soft magnetic material is an aggregate of permeable micro-domains separated by insulation boundaries. |
| FILED | Thursday, January 16, 2020 |
| APPL NO | 16/744382 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/02 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 4/08 (20130101) Original (OR) Class C23C 4/129 (20160101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/24 (20130101) H01F 1/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180877 | Wong |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Shing-Chung Josh Wong (Akron, Ohio) |
| ASSIGNEE(S) | The University of Akron (Akron, Ohio) |
| INVENTOR(S) | Shing-Chung Josh Wong (Akron, Ohio) |
| ABSTRACT | A dry adhesive includes a first plurality of fiber segments mechanically interlocked with a second plurality of fiber segments. A dry adhesive can include a first plurality of fibers mechanically interlocked with a second plurality of fibers or a single plurality of fibers having a first end region mechanically interlocked with a second end region. The fiber segments and fibers can be aligned, electrospun nanofibers. One or more continuous and scalable methods of making aligned fibers are also provided. One or more apparatuses are also provided. |
| FILED | Wednesday, July 25, 2018 |
| APPL NO | 16/044934 |
| ART UNIT | 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 5/00 (20130101) C09J 2301/31 (20200801) C09J 2400/263 (20130101) Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding D04H 1/74 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 29/49801 (20150115) Y10T 29/53526 (20150115) Y10T 428/24132 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11181383 | Amini et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Toyota Research Institute, Inc. (Los Altos, California); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Toyota Research Institute, Inc. (Los Altos, California); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Alexander Amini (Cambridge, Massachusetts); Guy Rosman (Newton, Massachusetts); Sertac Karaman (Cambridge, Massachusetts); Daniela Rus (Weston, Massachusetts) |
| ABSTRACT | Systems and methods described herein relate to vehicular navigation and localization. One embodiment extracts perceptual features from sensor data; extracts unrouted-map features from unrouted map data; combines the perceptual features and the unrouted-map features to produce first combined features data; outputs, based at least in part on the first combined features data, parameters of a probability distribution for one or more steering trajectories that are available to a vehicle; and performs a localization of the vehicle based, at least in part, on the parameters of the probability distribution. |
| FILED | Wednesday, May 08, 2019 |
| APPL NO | 16/406809 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 10/04 (20130101) B60W 10/18 (20130101) B60W 10/20 (20130101) B60W 30/18 (20130101) B60W 40/10 (20130101) B60W 2400/00 (20130101) B60W 2420/42 (20130101) B60W 2420/52 (20130101) B60W 2420/54 (20130101) B60W 2710/18 (20130101) B60W 2710/20 (20130101) B60W 2720/106 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/28 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11181482 | Pyayt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Anna Pyayt (Tampa, Florida); Arsenii Zhdanov (Tampa, Florida); Jordan Keefe (St. Petersburg, Florida); Luis Franco-Waite (Lutz, Florida) |
| ABSTRACT | A mobile phone-based system for ELISA (MELISA). The MELISA system can perform all steps of ELISA procedure and output hormone concentration values. The system includes a heater that keeps the temperature required for sample incubation, illumination system for sample image capturing, and a digital camera system. All components are enclosed in a dark box to create optimal light conditions for image capturing. After sample images are captured, they are digitally processed, and hormone concentration values are reported based on colorimetric data from the samples. The system can be used to complete all steps of the assay, including incubation and reading. It is lightweight, can be fabricated at low cost, is portable, and can transfer test results via mobile phone. MELISA can be calibrated for accurate measurements of progesterone and has demonstrated successful measurements with the calibrated system. |
| FILED | Wednesday, September 05, 2018 |
| APPL NO | 16/121932 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/29 (20130101) G01N 21/78 (20130101) Original (OR) Class G01N 21/253 (20130101) G01N 21/274 (20130101) G01N 21/0332 (20130101) G01N 21/6452 (20130101) G01N 33/569 (20130101) G01N 33/574 (20130101) G01N 33/54386 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11181520 | Yuan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Baohong Yuan (Arlington, Texas); Bingbing Cheng (Dallas, Texas); Mingyuan Wei (Arlington, Texas) |
| ABSTRACT | Methods of imaging described herein comprises disposing a first and second ultrasound-switchable fluorophore in an environment; exposing the environment to an ultrasound beam to create an activation region; disposing the first and/or second fluorophore within the activation region to switch the first and/or second fluorophore from an off state to an on state; exposing the environment to a beam of electromagnetic radiation; detecting a first photoluminescence signal at a first location within the environment, the photoluminescence signal comprising at least one of a first ultrasound fluorescence signal emitted by the first fluorophore, a first fluorescence signal emitted by the second fluorophore, and a background signal; correlating the first photoluminescence signal with a first reference signal to generate a correlation coefficient for the first location; and multiplying the first photoluminescence signal by the first correlation coefficient for the first location to generate a first modified photoluminescence signal for the first location. |
| FILED | Thursday, June 27, 2019 |
| APPL NO | 16/455157 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0071 (20130101) A61B 8/481 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 41/0028 (20130101) A61K 49/0034 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 33/542 (20130101) G01N 33/5091 (20130101) Original (OR) Class G01N 2201/06113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11181665 | Mecikalski |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | John R. Mecikalski (Madison, Alabama) |
| ASSIGNEE(S) | Board of Trustees of the University of Alabama (Huntsville, Alabama) |
| INVENTOR(S) | John R. Mecikalski (Madison, Alabama) |
| ABSTRACT | A weather forecasting system may receive satellite image samples and identify an updraft and components of the updraft within a cloud. These satellite image samples are collected over time (e.g., at 30 second to 1 minute time intervals). The system may identify an area of rotation and/or divergence at cloud top in a cumulus cloud or mature convective storm over time by comparing the samples and determine a parameter indicative of the updraft based on the area of rotation and divergence. The system may estimate aspects of the environment related to storm development and predict the occurrence of a weather event in the future based on the parameter and generate an output indicative of the occurrence. |
| FILED | Friday, March 20, 2020 |
| APPL NO | 16/824850 |
| ART UNIT | 2862 — Printing/Measuring and Testing |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 43/00 (20130101) Meteorology G01W 1/10 (20130101) Original (OR) Class G01W 2001/003 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/1062 (20190501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11181668 | Chisum et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Notre Dame du Lac (Notre Dame, Indiana) |
| ASSIGNEE(S) | University of Notre Dame du Lac (Notre Dame, Indiana) |
| INVENTOR(S) | Jonathan Chisum (Notre Dame, Indiana); Nicolas Garcia (South Bend, Indiana) |
| ABSTRACT | A film comprising a first plurality of voids is provided, wherein respective ones of the first plurality of voids have a regular n-gon geometry, and the first plurality of voids are arranged on a regular n-gon lattice having a first size. The film may comprise a second plurality of voids arranged on a regular n-gon lattice having a second size different from the first size. An optical element and manufacturing method are also provided. |
| FILED | Friday, July 12, 2019 |
| APPL NO | 16/509856 |
| ART UNIT | 2637 — Optical Communications |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 3/0087 (20130101) Original (OR) Class Antennas, i.e Radio Aerials H01Q 15/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11181727 | Howard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF NOTRE DAME DU LAC (South Bend, Indiana) |
| ASSIGNEE(S) | UNIVERSITY OF NOTRE DAME DU LAC (South Bend, Indiana) |
| INVENTOR(S) | Scott Howard (Notre Dame, Indiana); Genevieve Vigil (South Bend, Indiana); Yide Zhang (South Bend, Indiana) |
| ABSTRACT | One aspect of the present disclosure relates to systems and methods that can be used for super-sensitivity multiphoton frequency-domain fluorescence lifetime imaging microscopy (MPM-FD-FLIM). One or more laser light sources can deliver excitation light with an intensity modulated by a periodic function to a sample, which includes a fluorophore concentration. A receiver can receive a fluorescence signal emitted from the fluorophore concentration over a time period. A computing device can transform the fluorescence signal to the frequency domain and measure a fluorescence lifetime associated with the sample in the frequency domain based on a DC component and at least one higher harmonic component generated by non-linear optical mixing of the modulated excitation light. Using the DC component and the at least one higher harmonic component can increase the sensitivity of an image created by the MPM-FD-FLIM system. |
| FILED | Friday, March 10, 2017 |
| APPL NO | 16/076172 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/06 (20130101) Original (OR) Class G02B 21/16 (20130101) G02B 21/365 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11181746 | Hua et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona); AUGMENTED VISION, INC (Tucson, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona); AUGMENTED VISION, INC (Tucson, Arizona) |
| INVENTOR(S) | Hong Hua (Tucson, Arizona); Chunyu Gao (Tucson, Arizona) |
| ABSTRACT | Eye-tracked head-mounted displays are provide which, in one aspect, may utilize the same optics for eyetracking and image viewing, with a selected portion of the optics used for an eyetracking optical path and a selected portion of the display optics used for an image viewing optical path. |
| FILED | Thursday, January 28, 2021 |
| APPL NO | 17/160492 |
| ART UNIT | 2692 — Selective Visual Display Systems |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/04 (20130101) G02B 17/086 (20130101) G02B 17/0896 (20130101) G02B 27/017 (20130101) G02B 27/0093 (20130101) G02B 27/0172 (20130101) Original (OR) Class G02B 2027/011 (20130101) G02B 2027/0138 (20130101) G02B 2027/0187 (20130101) Electric Digital Data Processing G06F 3/013 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11183175 | Larson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Clinc, Inc. (Ann Arbor, Michigan) |
| ASSIGNEE(S) | Clinc, Inc. (Ann Arbor, Michigan) |
| INVENTOR(S) | Stefan Larson (Ann Arbor, Michigan); Kevin Leach (Ann Arbor, Michigan); Michael A. Laurenzano (Ann Arbor, Michigan) |
| ABSTRACT | A system and method of implementing an intuitive search interface for tactically searching one or more annotated utterance corpora in a machine learning-based dialogue system includes identifying an utterance corpus query for searching one or more annotated utterance corpora of a machine learning-based dialogue system; interpreting the utterance corpus query by translating the utterance corpus query into one or more search expressions recognizable to an utterance sample retrieval program searchably interfacing with the one or more annotated utterance corpora of the machine learning-based dialogue system; retrieving one or more annotated utterance samples from the one or more annotated utterance corpora based on the interpretation of the utterance corpus query; and returning the one or more annotated utterance samples to an intuitive utterance corpus search interface. |
| FILED | Wednesday, February 17, 2021 |
| APPL NO | 17/178052 |
| ART UNIT | 2656 — Digital Audio Data Processing |
| CURRENT CPC | Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/16 (20130101) Original (OR) Class G10L 15/22 (20130101) G10L 15/063 (20130101) G10L 15/1822 (20130101) G10L 2015/223 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11184201 | Prothero |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Astrapi Corporation (Dallas, Texas) |
| ASSIGNEE(S) | Astrapi Corporation (Dallas, Texas) |
| INVENTOR(S) | Jerrold Prothero (Delray Beach, Florida) |
| ABSTRACT | Systems, devices, and methods of the present invention facilitate secure communication by altering the set of symbol waveforms that may be in use in particular symbol times defined herein as Symbol Waveform Hopping. SWH may be enabled by selecting two or more modulation formats that have sufficiently comparable communication performance (e.g., occupied bandwidth and signal power efficiency), but characterized by symbol waveform alphabet that include different symbol waveform, so that the overall transmission/communication performance of data stream in a signal transmission channel of the system is not significantly affected by switching between modulation formats. Some or all of the symbol waveforms in each alphabet may not be present in other alphabets. |
| FILED | Wednesday, November 18, 2020 |
| APPL NO | 16/952066 |
| ART UNIT | 2632 — Digital Communications |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) H04L 1/0618 (20130101) H04L 5/0023 (20130101) H04L 27/0008 (20130101) Original (OR) Class H04L 27/34 (20130101) H04L 27/2602 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11184976 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Joseph Wang (San Diego, California); Rajan Kumar (La Jolla, California); Ying Shirley Meng (San Diego, California); Jae Wook Shin (La Jolla, California); Lu Yin (San Diego, California) |
| ABSTRACT | Disclosed are compositions, devices, systems and fabrication methods for stretchable composite materials and stretchable electronics devices. In some aspects, an elastic composite material for a stretchable electronics device includes a first material having a particular electrical, mechanical or optical property; and a multi-block copolymer configured to form a hyperelastic binder that creates contact between the first material and the multi-block copolymer, in which the elastic composite material is structured to stretch at least 500% in at least one direction of the material and to exhibit the particular electrical, mechanical or optical property imparted from the first material. In some aspects, the stretchable electronics device includes a stretchable battery, biofuel cell, sensor, supercapacitor or other device able to be mounted to skin, clothing or other surface of a user or object. |
| FILED | Tuesday, November 13, 2018 |
| APPL NO | 16/189701 |
| ART UNIT | 2848 — Electrical Circuits and Systems |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1477 (20130101) A61B 5/14865 (20130101) A61B 2562/164 (20130101) A61B 2562/166 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 13/4902 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/158 (20170801) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 297/046 (20130101) Compositions of Macromolecular Compounds C08L 53/02 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/48 (20130101) H01M 4/622 (20130101) H01M 4/663 (20130101) H01M 4/666 (20130101) H01M 4/668 (20130101) H01M 10/24 (20130101) H01M 10/0565 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/16 (20130101) H05K 1/028 (20130101) H05K 1/118 (20130101) H05K 1/0283 (20130101) Original (OR) Class H05K 1/0393 (20130101) H05K 3/326 (20130101) H05K 2201/0133 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11178828 | Henry et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
| ASSIGNEE(S) | The Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
| INVENTOR(S) | Christopher G. Henry (Stuttgart, Arkansas); Brian Koehler (Ainsworth, Iowa); Jim Nichols (Caro, Michigan) |
| ABSTRACT | A gravity irrigation system includes a distribution piping having apertures to distribute water to a field, and a valve located upstream of the distribution piping. The valve limits a pressure of the water being delivered to the distribution piping. The system also includes a sump to receive the water at a lowest elevation of the field, a depth sensor disposed within the sump, and a return pump disposed at least partially within the sump to move the water to an elevated portion of the field. The system also includes a motor to drive the return pump, and a power source coupled to a variable frequency drive that powers the motor and controls a motor speed proportionately to an indication of the depth sensor. The system also includes a transfer piping to bring the water from the return pump to a check valve and to the distribution piping. |
| FILED | Friday, December 15, 2017 |
| APPL NO | 16/471699 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 25/02 (20130101) Original (OR) Class A01G 25/06 (20130101) Hydraulic Engineering E02B 13/00 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 1/22 (20130101) F16K 37/005 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 10/40 (20141201) H02S 20/30 (20141201) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 60/12 (20151101) Y02P 60/14 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11179673 | Pavlish et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Midwest Energy Emissions Corp. (Lewis Center, Ohio) |
| ASSIGNEE(S) | Midwwest Energy Emission Corp. (Corsicana, Texas) |
| INVENTOR(S) | John H. Pavlish (East Grand Forks, Minnesota); Edwin S. Olson (Grand Forks, North Dakota); Michael J. Holmes (Thompson, North Dakota) |
| ABSTRACT | Various embodiments disclosed relate to sorbents for the oxidation and removal of mercury. The present invention includes removing mercury from a mercury-containing gas using a halide-promoted and optionally ammonium-protected sorbent that can include carbon sorbent, non-carbon sorbent, or a combination thereof. |
| FILED | Friday, December 22, 2017 |
| APPL NO | 15/853029 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/10 (20130101) B01D 53/64 (20130101) Original (OR) Class B01D 53/83 (20130101) B01D 2251/108 (20130101) B01D 2251/206 (20130101) B01D 2253/102 (20130101) B01D 2257/602 (20130101) B01D 2258/0283 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/04 (20130101) B01J 20/10 (20130101) B01J 20/12 (20130101) B01J 20/20 (20130101) B01J 20/027 (20130101) B01J 20/041 (20130101) B01J 20/043 (20130101) B01J 20/106 (20130101) B01J 20/223 (20130101) B01J 20/0262 (20130101) B01J 20/3416 (20130101) B01J 20/28004 (20130101) B01J 2220/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11179682 | Yildiz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Bilge Yildiz (Cambridge, Massachusetts); Nikolai Tsvetkov (Cambridge, Massachusetts); Qiyang Lu (Cambridge, Massachusetts) |
| ABSTRACT | A method and a composition to stabilize the surface cation chemistry of the perovskite or related oxides, and thus, to minimize or completely avoid the detrimental segregation and phase separation of dopant cations at the surface can include modifying the surface with more oxidizable metal cations and/or more oxidizable metal oxides, thereby reducing the oxygen vacancy concentration at the very surface. |
| FILED | Wednesday, March 30, 2016 |
| APPL NO | 15/563535 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/228 (20130101) B01D 71/024 (20130101) Original (OR) Class Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/83 (20130101) B01J 2523/00 (20130101) B01J 2523/00 (20130101) B01J 2523/24 (20130101) B01J 2523/24 (20130101) B01J 2523/842 (20130101) B01J 2523/842 (20130101) B01J 2523/845 (20130101) B01J 2523/845 (20130101) B01J 2523/3706 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/34 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 11/0773 (20210101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/08 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/9025 (20130101) H01M 4/9033 (20130101) H01M 2008/1293 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180394 | Yan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Y. Eugene Yan (Naperville, Illinois); Louis E. Martino (Clarksville, Maryland); Lorraine M. LaFreniere (Joliet, Illinois) |
| ABSTRACT | A method for treating chemicals below ground is provided. The system includes contacting the chemicals with a rhizosphere to maximize transpiration rate and minimize over-saturation of the rhizosphere. Also provided is a method for using contaminated groundwater as a sole source of irrigation. The method uses extracting the contaminated water and pumping the extracted water to an irrigation zone under the control of an autonomous irrigation system. Each zone includes some trees and the root system for each tree is modified to function as a treatment cell. The invention also provides a system for treating contaminated water, using a contaminated water source situated below ground surface. The system uses a pump for extracting contaminated water from the water source and prevents the contaminated water from directly contacting the atmosphere above the ground surface. Vegetation which defines an underground rhizosphere is adapted to directly receive the water. |
| FILED | Monday, September 30, 2019 |
| APPL NO | 16/588154 |
| ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Reclamation of Contaminated Soil B09C 1/002 (20130101) B09C 1/08 (20130101) B09C 1/105 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 3/32 (20130101) Original (OR) Class C02F 2103/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180621 | Murdock et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of South Carolina (Columbia, South Carolina) |
| ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
| INVENTOR(S) | Laura A. Murdock (Columbia, South Carolina); Fei Huang (West Columbia, South Carolina); Lihui Wang (Emeryville, California); Brian C. Benicewicz (Columbia, South Carolina) |
| ABSTRACT | A novel process for making PBI films starting from gel PBI membranes polymerized and casted in the PPA process wherein acid-imbibed gel PBIs are neutralized in a series of water baths and undergo controlled drying in association with a substrate material, yielding a PBI film without the use of organic solvents. |
| FILED | Friday, September 13, 2019 |
| APPL NO | 16/569983 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Separation B01D 67/0011 (20130101) B01D 67/0013 (20130101) B01D 67/0093 (20130101) B01D 2323/30 (20130101) B01D 2323/40 (20130101) B01D 2325/02 (20130101) B01D 2325/42 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/2256 (20130101) Original (OR) Class C08J 2379/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180670 | Perez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Lemuel Perez Perez (Livermore, California); Eric B. Duoss (Dublin, California); Jeremy Lenhardt (Tracy, California); Thomas S. Wilson (San Leandro, California) |
| ABSTRACT | According to one embodiment, a silicone-based ink for additive manufacturing includes a vinyl-terminated diphenyl siloxane macromer, a treated silica hydrophobic reinforcing filler, a rheology modifying additive, and a plurality of porogen particles. According to another embodiment, a product of additive manufacturing with a silicone-based ink includes a plurality of continuous filaments comprised of a siloxane matrix, where the continuous filaments are arranged in a geometric pattern, a plurality of inter-filament pores defined by the geometric pattern of the continuous filaments, and a plurality of intra-filament pores having an average diameter in a range of greater than 1 micron to less than 50 microns. |
| FILED | Thursday, March 28, 2019 |
| APPL NO | 16/368725 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/118 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 70/00 (20141201) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 77/20 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/26 (20130101) C08J 2201/042 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/013 (20180101) C08K 3/36 (20130101) C08K 5/21 (20130101) C08K 7/22 (20130101) C08K 9/06 (20130101) C08K 2201/003 (20130101) C08K 2201/006 (20130101) Compositions of Macromolecular Compounds C08L 71/02 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/16 (20130101) Original (OR) Class C09D 11/101 (20130101) C09D 11/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180702 | Sunkara et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Advanced Energy Materials, LLC (Louisville, Kentucky) |
| ASSIGNEE(S) | Advanced Energy Materials, LLC (Louisville, Kentucky) |
| INVENTOR(S) | Mahendra K. Sunkara (Louisville, Kentucky); Sivakumar Vasireddy (Louisville, Kentucky); Juan He (Louisville, Kentucky); Vivekanand Kumar (Louisville, Kentucky) |
| ABSTRACT | The present development is a metal particle coated nanowire catalyst for use in the hydrodesulfurization of fuels and a process for the production of the catalyst. The catalyst comprises titanium(IV) oxide nanowires wherein the nanowires are produced by exposure of a TiO2—KOH paste to microwave radiation. Metal particles selected from the group consisting of molybdenum, nickel, cobalt, tungsten, or a combination thereof, are impregnated on the metal oxide nanowire surface. The metal impregnated nanowires are sulfided to produce catalytically-active metal particles on the surface of the nanowires The catalysts of the present invention are intended for use in the removal of thiophenic sulfur from liquid fuels through a hydrodesulfurization (HDS) process in a fixed bed reactor. The presence of nanowires improves the HDS activity and reduces the sintering effect, therefore, the sulfur removal efficiency increases. |
| FILED | Friday, January 31, 2020 |
| APPL NO | 16/779016 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/04 (20130101) B01J 21/08 (20130101) B01J 21/063 (20130101) B01J 23/14 (20130101) B01J 23/882 (20130101) B01J 23/883 (20130101) B01J 27/0515 (20130101) B01J 35/006 (20130101) B01J 35/06 (20130101) B01J 35/023 (20130101) B01J 37/20 (20130101) B01J 37/346 (20130101) B01J 37/349 (20130101) B01J 2523/00 (20130101) B01J 2523/00 (20130101) B01J 2523/00 (20130101) B01J 2523/00 (20130101) B01J 2523/31 (20130101) B01J 2523/31 (20130101) B01J 2523/47 (20130101) B01J 2523/47 (20130101) B01J 2523/47 (20130101) B01J 2523/68 (20130101) B01J 2523/68 (20130101) B01J 2523/68 (20130101) B01J 2523/845 (20130101) B01J 2523/845 (20130101) B01J 2523/847 (20130101) B01J 2523/847 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/03 (20130101) C01P 2004/13 (20130101) C01P 2004/64 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 47/04 (20130101) Original (OR) Class C10G 47/12 (20130101) C10G 2300/202 (20130101) C10G 2300/207 (20130101) C10G 2400/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180743 | Doudna et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jennifer A. Doudna (Berkeley, California); David Burstein (Berkeley, California); Janice S. Chen (Berkeley, California); Lucas B. Harrington (Berkeley, California); David Paez-Espino (Walnut Creek, California); Jillian F. Banfield (Berkeley, California) |
| ABSTRACT | Provided are compositions and methods that include one or more of: (1) a “CasZ” protein (also referred to as a CasZ polypeptide), a nucleic acid encoding the CasZ protein, and/or a modified host cell comprising the CasZ protein (and/or a nucleic acid encoding the same); (2) a CasZ guide RNA that binds to and provides sequence specificity to the CasZ protein, a nucleic acid encoding the CasZ guide RNA, and/or a modified host cell comprising the CasZ guide RNA (and/or a nucleic acid encoding the same); and (3) a CasZ transactivating noncoding RNA (trancRNA) (referred to herein as a “CasZ trancRNA”), a nucleic acid encoding the CasZ trancRNA, and/or a modified host cell comprising the CasZ trancRNA (and/or a nucleic acid encoding the same). |
| FILED | Wednesday, February 12, 2020 |
| APPL NO | 16/789049 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 2319/09 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 15/11 (20130101) C12N 15/113 (20130101) C12N 2310/20 (20170501) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180839 | Shyam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); Nemak USA, Inc. (Southfield, Michigan); FCA US LLC (Auburn Hills, Michigan) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); Nemak USA, Inc. (Southfield, Michigan); FCA US LLC (Auburn Hills, Michigan) |
| INVENTOR(S) | Amit Shyam (Knoxville, Tennessee); James A. Haynes (Knoxville, Tennessee); Jose Alejandro Gonzalez Villarreal (Garcia, Mexico); Andres Fernando Rodriguez-Jasso (Garcia, Mexico); Gregg Thomas Black (Wayne County, Michigan); Christopher Randall Glaspie (Oakland County, Michigan); Seyed M. Mirmiran (Auburn Hills, Michigan) |
| ABSTRACT | Disclosed herein are embodiments of an aging heat treatment that can be used to replace conventional aging steps when making alloy embodiments of the present disclosure. Embodiments of the disclosed aging heat treatment reduce cost and complexity in producing aluminum alloy-based components while also promoting and/or improving microstructure stability of the aluminum alloys. |
| FILED | Thursday, October 25, 2018 |
| APPL NO | 16/171201 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 27/04 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0003 (20130101) Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 2211/004 (20130101) C21D 2221/00 (20130101) Alloys C22C 1/026 (20130101) C22C 21/12 (20130101) C22C 21/14 (20130101) C22C 21/16 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/057 (20130101) Original (OR) Class Pistons; Cylinders; Sealings F16J 1/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11181020 | Babbitt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ONBOARD DYNAMICS, INC. (Bend, Oregon) |
| ASSIGNEE(S) | ONBOARD DYNAMICS, INC. (Bend, Oregon) |
| INVENTOR(S) | Guy Robert Babbitt (Fort Collins, Colorado); Daniel Scott Pedersen (Fort Collins, Colorado) |
| ABSTRACT | An internal combustion engine may be used to compress natural gas for vehicle fuel. The engine may contain a plurality of gas compression cylinders, at least one standard combustion cylinder to drive the compression cylinders, and a common crankshaft in a crankcase coupling the compression cylinders and the at least one standard combustion cylinder. Some combustible gas being compressed may leak past the piston rings of the compression cylinders into the engine crankcase posing a safety concern. This invention eliminates this concern by actively flushing the crankcase at a higher rate than normal. |
| FILED | Wednesday, March 28, 2018 |
| APPL NO | 16/603146 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Lubricating of Machines or Engines in General; Lubricating Internal Combustion Engines; Crankcase Ventilating F01M 13/0011 (20130101) F01M 13/022 (20130101) Original (OR) Class F01M 13/028 (20130101) F01M 2013/0044 (20130101) Internal-combustion Piston Engines; Combustion Engines in General F02B 2075/027 (20130101) Supplying Combustion Engines in General With Combustible Mixtures or Constituents Thereof F02M 35/10222 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11181043 | Berry |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Jonathan Dwight Berry (Simpsonville, South Carolina) |
| ABSTRACT | Apparatuses for generating carbon particles and exhaust gas used by gas turbine systems are disclosed. One apparatus may include a decarbonization component combusting or reacting a mixture of a fuel and a mixing gas to generate the carbon particles and the exhaust gas and an exhaust conduit to receive the exhaust gas generated by the decarbonization component. The apparatus may also include a mixing duct in fluid communication with the exhaust conduit and the gas turbine system. The mixing duct may receive the exhaust gas and provide the exhaust gas to the gas turbine system to be used to produce a working fluid within the gas turbine system. The apparatus may further include a carbon particle collection component for receiving and storing the generated carbon particles. |
| FILED | Monday, September 30, 2019 |
| APPL NO | 16/587320 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/05 (20170801) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/20 (20130101) Original (OR) Class F02C 3/34 (20130101) F02C 6/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11181236 | Aceves et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California); FORD MOTOR COMPANY (Dearborn, Michigan); Klaus Szoucsek (Munich, Germany) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California); Ford Motor Company (Dearborn, Michigan) |
| INVENTOR(S) | Salvador Aceves (Livermore, California); John Elmer (Danville, California); Francisco Espinosa-Loza (Livermore, California); Guillaume Petitpas (Livermore, California); James Smith (Livermore, California); Michael Veenstra (Dearborn, Michigan); Klaus Szoucsek (Munich, Germany) |
| ABSTRACT | In one aspect the present disclosure relates to a method of manufacturing a cryogenic pressure vessel. The method may include providing a metal lined, composite wrapped vessel which has a boss. The method may further include securing an inlet to the boss, and then encapsulating the metal lined, composite wrapped vessel within a metallic layer in a vacuum controlled environment to form an encapsulated inner tank subassembly. The method may further include securing at least one support to an exterior of the encapsulated inner tank subassembly, and within the controlled vacuum environment, applying a metal coating over the encapsulated inner tank subassembly and the at least one support to form a metal coated, encapsulated inner tank subassembly. The method may further include, within the controlled vacuum environment, encapsulating the metal coated, encapsulated inner tank subassembly within a metallic vacuum jacket, which forms the cryogenic pressure vessel. |
| FILED | Monday, August 27, 2018 |
| APPL NO | 16/642684 |
| ART UNIT | 3733 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 13/001 (20130101) Original (OR) Class F17C 2201/035 (20130101) F17C 2201/0109 (20130101) F17C 2203/032 (20130101) F17C 2203/0391 (20130101) F17C 2203/0604 (20130101) F17C 2203/0607 (20130101) F17C 2203/0629 (20130101) F17C 2203/0643 (20130101) F17C 2203/0646 (20130101) F17C 2205/018 (20130101) F17C 2209/221 (20130101) F17C 2209/232 (20130101) F17C 2209/234 (20130101) F17C 2221/012 (20130101) F17C 2223/0161 (20130101) F17C 2260/013 (20130101) F17C 2270/0105 (20130101) F17C 2270/0131 (20130101) F17C 2270/0171 (20130101) F17C 2270/0176 (20130101) F17C 2270/0189 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11181326 | Ma et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Zhiwen Ma (Golden, Colorado); Patrick Gordon Davenport (Boulder, Colorado); Janna Martinek (Lafayette, Colorado) |
| ABSTRACT | Methods and devices for long-duration electricity storage using low-cost thermal energy storage and high-efficiency power cycle, are disclosed. In some embodiments it has the potential for superior long-duration, low-cost energy storage. |
| FILED | Tuesday, September 24, 2019 |
| APPL NO | 16/580421 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 17/005 (20130101) F28D 20/0043 (20130101) Original (OR) Class F28D 20/0056 (20130101) F28D 2020/0078 (20130101) F28D 2020/0082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11181446 | Kertesz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Vilmos Kertesz (Oak Ridge, Tennessee); Bernadeta R. Srijanto (Knoxville, Tennessee); Charles P. Collier (Knoxville, Tennessee); John F. Cahill (Knoxville, Tennessee) |
| ABSTRACT | A method and system for sampling a solid sample material can include the step of mounting the sample material on a support. A sample surface is coated with a surface treatment composition in a dry deposition process. A solvent supply conduit for supplying solvent to the sample surface and a solvent exhaust conduit for withdrawing solvent from the sample surface can be provided. Solvent is flowed from the solvent supply conduit to the surface treatment composition and the sample surface such that the solvent contacts the surface treatment composition. A laser beam is directed from a laser source to the sample and the surface treatment composition. The laser beam will ablate the sample and the surface treatment composition in portions intersected by the laser beam. Ablated sample material enters the solvent liquid and will be transported with the solvent away from the sample surface through the solvent exhaust conduit. |
| FILED | Friday, February 21, 2020 |
| APPL NO | 16/797712 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/04 (20130101) Original (OR) Class G01N 1/38 (20130101) G01N 2001/045 (20130101) G01N 2001/383 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/164 (20130101) H01J 49/0463 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11181564 | Ghosh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Soumyadip Ghosh (Peekskill, New York); Dung Phan (Ossining, New York); Xu Sun (Atlanta, Georgia) |
| ABSTRACT | A method for determining power output levels of a plurality of nodes in an electric power system includes receiving, at a first node of the plurality of nodes, voltage information and multipliers of all neighboring nodes of the first node within the electric power system, determining, by the first node, a local power generation and a local voltage using the voltage information and the multipliers of the neighboring nodes and distributing the local power generation and the local voltage to the neighboring nodes, determining, by the first node, an estimated voltage of each of the neighboring nodes and distributing the estimated voltage to each of the neighboring nodes, and updating, by the first node, a local multiplier using the voltage information received from the neighboring nodes and the estimated voltage of each of the neighboring nodes determined by the node. |
| FILED | Sunday, June 29, 2014 |
| APPL NO | 14/318658 |
| ART UNIT | 2865 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 19/2513 (20130101) G01R 21/133 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11183309 | O'Brien |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Robert C. O'Brien (Idaho Falls, Idaho) |
| ABSTRACT | A method of forming a fuel rod for a nuclear reactor comprises disposing a powder comprising particles of a fuel material on a substrate, exposing the powder to energy from an energy source to form a first layer of a nuclear fuel, the first layer comprising inter-granular bonds between the particles of the fuel material, disposing additional powder comprising particles of the fuel material over the first layer of the nuclear fuel, and exposing the additional powder to energy from the energy source to form a second layer of the nuclear fuel and to form the nuclear fuel to have a void fraction greater than about 0.20, the second layer comprising inter-granular bonds between the additional powder and the first layer of the nuclear fuel. Related nuclear fuels comprising a porous structure, fuel rods, nuclear reactors, and methods are disclosed. |
| FILED | Friday, December 14, 2018 |
| APPL NO | 16/220661 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Nuclear Reactors G21C 3/20 (20130101) G21C 3/044 (20130101) Original (OR) Class G21C 3/623 (20130101) G21C 21/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11183390 | Nichol et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nokomis, Inc. (Charleroi, Pennsylvania) |
| ASSIGNEE(S) | NOKOMIS, INC. (Charleroi, Pennsylvania) |
| INVENTOR(S) | Robert Michael Nichol (Washington, Pennsylvania); Walter John Keller, III (Bridgeville, Pennsylvania); Todd Eric Chornenky (Carmichaels, Pennsylvania) |
| ABSTRACT | A method for creating an enhanced multipaction resistant diamond-like coating (DLC) coating with lower Secondary Electron Emission (SEE) properties is performed on an initial surface by etching a DLC coating deposited on the surface after deposition and optionally creating interlayers to enhance adhesion mechanical properties between the DLC coating and the initial surface. |
| FILED | Tuesday, August 14, 2018 |
| APPL NO | 16/103519 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/0245 (20130101) C23C 16/276 (20130101) C23C 16/0281 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 1/32 (20130101) H01J 9/125 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02019 (20130101) H01L 21/02043 (20130101) H01L 21/02376 (20130101) H01L 21/3065 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11183670 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Jian Li (Tempe, Arizona); Kody George Klimes (Phoenix, Arizona) |
| ABSTRACT | An organic light emitting diode (OLED) device includes an emissive layer having a first sublayer with a first emitter as a dopant, a second sublayer with a second emitter as a dopant, and a third sublayer with a third emitter as a dopant. The second sublayer is between the first sublayer and the third sublayer. A concentration of the first emitter in the first sublayer exceeds a concentration of the third emitter in the third sublayer, and the concentration of the third emitter in the third sublayer exceeds a concentration of the second emitter in the second sublayer. |
| FILED | Monday, December 18, 2017 |
| APPL NO | 15/845575 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/006 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/185 (20130101) C09K 2211/1014 (20130101) C09K 2211/1044 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0008 (20130101) H01L 51/56 (20130101) H01L 51/0084 (20130101) H01L 51/504 (20130101) H01L 51/5016 (20130101) H01L 51/5278 (20130101) Original (OR) Class H01L 2251/558 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11183688 | Abruña et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Héctor D. Abruña (Ithaca, New York); Na Zhang (Ithaca, New York) |
| ABSTRACT | Provided are porous Fe3O4/sulfur composites. The composites are composed of porous Fe3O4 nanoparticles and sulfur, where the sulfur loading is 70-85% by weight based on the total weight of the composite. Also provided are batteries having cathodes containing porous FE3O4 composites of the present disclosure. |
| FILED | Monday, December 31, 2018 |
| APPL NO | 16/959086 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) Original (OR) Class H01M 4/364 (20130101) H01M 4/483 (20130101) H01M 10/44 (20130101) H01M 10/0525 (20130101) H01M 2004/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11183946 | Huynh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Phuc Thanh Huynh (Urbana, Illinois); Arijit Banerjee (Urbana, Illinois) |
| ABSTRACT | This disclosure relates AC-to-DC rectification and power flow control of electrical power generators. An integrated rectifier-generator AC-DC conversion circuit and system are disclosed for providing a regulated DC output. The integrated rectifier-generator AC-DC conversion circuit and system may include serially stacked passive and active rectifiers connected to multiple AC ports of an electrical power generator driven by mechanical energy captured by an energy harvester. The integrated rectifier-generator AC-DC conversion circuit and system may be configured to perform active ripple control and a maximum power tracking from the energy harvester by controlling a fraction of an overall power that flow through the active rectifier. |
| FILED | Thursday, March 12, 2020 |
| APPL NO | 16/817322 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/381 (20130101) H02J 2300/28 (20200101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/143 (20130101) H02M 7/06 (20130101) H02M 7/219 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11184087 | Buckley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Brandon Walter Buckley (Walnut Creek, California); David Simon Perlmutter (Oakland, California); Peter Thomas Setsuda DeVore (Livermore, California); Apurva Shantharaj Gowda (Mountain View, California); Jason Thomas Chou (Walnut Creek, California) |
| ABSTRACT | Devices, systems and methods for encoding information using optical components are described. Information associated with a first optical signal (e.g., an optical pump) is encoded onto the phase of a second optical signal (e.g., an optical probe) using cross phase modulation (XPM) in a non-linear optical medium. The optical signals are multiplexed together into the nonlinear optical medium. The probe experiences a modified index of refraction as it propagates through the medium and thus accumulates a phase change proportional to the intensity of the pump. The disclosed devices can be incorporated into larger components and systems for various applications such as scientific diagnostics, radar, remote sensing, wireless communications, and quantum computing that can benefit from encoding and generation of low noise, high resolution signals. Examples of the encoded information includes intrinsic noise from the optical source, or others signals of interest, such as electrical, optical, X-ray, or high-energy particle signals. |
| FILED | Friday, April 10, 2020 |
| APPL NO | 16/846143 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/21 (20130101) G02F 1/212 (20210101) G02F 1/365 (20130101) G02F 2/004 (20130101) G02F 2/006 (20210101) Transmission H04B 10/2557 (20130101) Original (OR) Class Multiplex Communication H04J 14/0221 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11184959 | Kisner |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Roger A. Kisner (Knoxville, Tennessee) |
| ABSTRACT | Conductors for use in heating systems are provided. The conductors are configured to have an extended current path for the current and increased resistance as seen by the current. The heating system may be an induction system. For example, the conductor may comprise a conductive material having a surface which faces an induction coil of an oscillating circuit. This surface may have a predetermined pattern of peaks and valleys. The peaks and valleys form a non-linear current path for the induced current when exposed to an electromagnetic field generated by the oscillating circuit. Other conductors such as a heat pipe may be used. The pipe may have walls with varying thicknesses over its length. The varying thicknesses may include a first thickness and a second thickness which alternate. The heat pipe may be used in an induction or direct contact heating system where AC is directly applied to the pipe. |
| FILED | Friday, January 04, 2019 |
| APPL NO | 16/240201 |
| ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Electric Heating; Electric Lighting Not Otherwise Provided for H05B 6/12 (20130101) Original (OR) Class H05B 6/062 (20130101) H05B 6/105 (20130101) H05B 6/1209 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11184976 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Joseph Wang (San Diego, California); Rajan Kumar (La Jolla, California); Ying Shirley Meng (San Diego, California); Jae Wook Shin (La Jolla, California); Lu Yin (San Diego, California) |
| ABSTRACT | Disclosed are compositions, devices, systems and fabrication methods for stretchable composite materials and stretchable electronics devices. In some aspects, an elastic composite material for a stretchable electronics device includes a first material having a particular electrical, mechanical or optical property; and a multi-block copolymer configured to form a hyperelastic binder that creates contact between the first material and the multi-block copolymer, in which the elastic composite material is structured to stretch at least 500% in at least one direction of the material and to exhibit the particular electrical, mechanical or optical property imparted from the first material. In some aspects, the stretchable electronics device includes a stretchable battery, biofuel cell, sensor, supercapacitor or other device able to be mounted to skin, clothing or other surface of a user or object. |
| FILED | Tuesday, November 13, 2018 |
| APPL NO | 16/189701 |
| ART UNIT | 2848 — Electrical Circuits and Systems |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1477 (20130101) A61B 5/14865 (20130101) A61B 2562/164 (20130101) A61B 2562/166 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 13/4902 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/158 (20170801) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 297/046 (20130101) Compositions of Macromolecular Compounds C08L 53/02 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/48 (20130101) H01M 4/622 (20130101) H01M 4/663 (20130101) H01M 4/666 (20130101) H01M 4/668 (20130101) H01M 10/24 (20130101) H01M 10/0565 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/16 (20130101) H05K 1/028 (20130101) H05K 1/118 (20130101) H05K 1/0283 (20130101) Original (OR) Class H05K 1/0393 (20130101) H05K 3/326 (20130101) H05K 2201/0133 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11178832 | Kaeppler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin); THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| INVENTOR(S) | Shawn Michael Kaeppler (Oregon, Wisconsin); Hannah Marie Schneider (Cologne, Minnesota); Jonathan Paul Lynch (Boalsburg, Pennsylvania); Malcolm John Bennett (Tollerton, United Kingdom) |
| ABSTRACT | The present invention relates to crop breeding. More particularly, the present invention relates to targeted modification of root angle to enhance abiotic stress tolerance in maize. In one aspect, the invention provides recombinant maize exhibiting increased root angle by decreasing the function of the maize ZMCIPK15 gene. Methods of making the recombinant maize and various methods of plant selection and breeding are further provided. |
| FILED | Friday, November 09, 2018 |
| APPL NO | 16/185739 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 1/04 (20130101) A01H 1/06 (20130101) Original (OR) Class A01H 5/10 (20130101) A01H 6/4684 (20180501) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/102 (20130101) C12N 15/1024 (20130101) C12N 15/8242 (20130101) C12N 15/8262 (20130101) C12N 15/8273 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6827 (20130101) C12Q 1/6895 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11178859 | Ciobanu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | The Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| INVENTOR(S) | Daniel Constantin Ciobanu (Lincoln, Nebraska); Lianna Rayne Walker (Lincoln, Nebraska); Taylor Benjamin Engle (Lincoln, Nebraska); Hiep Vu (Lincoln, Nebraska) |
| ABSTRACT | The present disclosure provides compositions and methods for increasing resistance to PCV2 infection in pigs. The increased resistance may be the result of siRNA or genetic modification through CRISPR or a vectored virus targeting SNPs that are resistant to PCV2 infection. |
| FILED | Monday, October 01, 2018 |
| APPL NO | 16/149059 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) Original (OR) Class A01K 2217/05 (20130101) A01K 2217/07 (20130101) A01K 2227/108 (20130101) A01K 2267/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8509 (20130101) C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11180765 | Curtiss, III et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Arizona Board of Regents for and on Behalf of Arizona State University (Scottsdale, Arizona); The Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | The Arizona Board of Regents for and on behalf of Arizona State University (Tempe, Arizona); The Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Roy Curtiss, III (Gainesville, Florida); Shifeng Wang (Gainesville, Florida); Soo-Young Wanda (Gainesville, Florida); Wei Kong (Phoenix, Arizona) |
| ABSTRACT | The invention relates to compositions and methods for making and using recombinant bacteria that are capable of regulated attenuation and/or regulated expression of one or more antigens of interest. |
| FILED | Tuesday, August 11, 2020 |
| APPL NO | 16/990033 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) A61K 39/00 (20130101) A61K 2035/11 (20130101) A61K 2039/522 (20130101) A61K 2039/523 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/36 (20130101) C12N 15/74 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 11180844 | Kitching |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
| INVENTOR(S) | John Kitching (Boulder, Colorado) |
| ABSTRACT | Making alkali metal vapor cells includes: providing a preform wafer that includes cell cavities in a cavity layer; providing a sealing wafer having a cover layer and transmission apertures; disposing a deposition assembly on the sealing wafer; disposing an alkali metal precursor in the deposition assembly; disposing the sealing wafer on the preform wafer; aligning the transmission apertures with the cell cavities; subjecting the alkali metal precursor to a reaction stimulus; producing alkali metal vapor in the deposition assembly; communicating the alkali metal vapor to the cell cavities; receiving, in the cell cavities, the alkali metal vapor from the transmission apertures; producing an alkali metal condensate in the cell cavity; moving the sealing wafer such that the cover layer encapsulates the alkali metal condensate in the cell cavities; and bonding the sealing wafer to the preform wafer to make individually sealed alkali metal vapor cells in the preform wafer. |
| FILED | Tuesday, March 19, 2019 |
| APPL NO | 16/357650 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 1/0008 (20130101) B23K 1/20 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 2203/031 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/18 (20130101) C23C 14/28 (20130101) C23C 14/046 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 29/49982 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11181489 | Thompson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lam Research Corporation (Fremont, California); Government of the USA, as represented by the Secretary of Commerce. (Gaithersburg, Maryland) |
| ASSIGNEE(S) | Lam Research Corporation (Fremont, California); The Government of the United States of America, represented by the Secretary of Commerce, National Institute of Standards and Technology (Gaithersburg, Maryland) |
| INVENTOR(S) | William Dean Thompson (Pleasanton, California); Regis Joseph Kline (Boonsboro, Maryland); Daniel F. Sunday (Gaithersburg, Maryland); Wenli Wu (Rockville, Maryland); Osman Sorkhabi (Danville, California); Jin Zhang (Fremont, California); Xiaoshu Chen (Fremont, California) |
| ABSTRACT | Provided herein are methods and apparatus for characterizing high aspect ratio (HAR) structures of fabricated or partially fabricated semiconductor devices. The methods involve using small angle X-ray scattering (SAXS) to determine average parameters of an array of HAR structures. In some implementations, SAXS is used to analyze symmetry of HAR structures in a sample and may be referred to as tilted structural symmetry analysis-SAXS (TSSA-SAXS) or TSSA. Analysis of parameters such as tilt, sidewall angle, bowing, and the presence of multiple tilts in HAR structures may be performed. |
| FILED | Tuesday, July 30, 2019 |
| APPL NO | 16/526858 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/18 (20130101) G01N 23/201 (20130101) Original (OR) Class G01N 2223/611 (20130101) G01N 2223/6113 (20130101) G01N 2223/6116 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11183567 | Slack et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Glen A. Slack (Scotia, New York); Leo J. Schowalter (Latham, New York) |
| ASSIGNEE(S) | Crystal IS, Inc. (Green Island, New York) |
| INVENTOR(S) | Glen A. Slack (Scotia, New York); Leo J. Schowalter (Latham, New York) |
| ABSTRACT | Fabrication of doped AlN crystals and/or AlGaN epitaxial layers with high conductivity and mobility is accomplished by, for example, forming mixed crystals including a plurality of impurity species and electrically activating at least a portion of the crystal. |
| FILED | Friday, May 15, 2020 |
| APPL NO | 16/874813 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 23/00 (20130101) C30B 29/403 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0254 (20130101) H01L 21/2258 (20130101) H01L 21/02579 (20130101) H01L 29/207 (20130101) Original (OR) Class H01L 29/2003 (20130101) H01L 33/325 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 11181648 | Pozzi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Sara Pozzi (Ann Arbor, Michigan); Shaun Clarke (Duns, United Kingdom); Marek Flaska (Spring Mills, Pennsylvania); Angela Di Fulvio (Champaign, Illinois) |
| ABSTRACT | A method for obtaining fast neutron and gamma ray quantities in an unknown neutron and gamma ray mixed field. The method is comprised of (1) a radiation detector capable of measuring neutrons and gamma rays, (2) identification of the neutron and the gamma ray interactions based on digital pulse shape analysis, (3) formation of a pulse height (or pulse area) histogram for both neutron and gamma ray events, (4) conversion of the neutron and gamma ray pulse height (or pulse area) histogram into a quantity of interest such as count rate, energy spectra, kerma, absorbed dose, and dose equivalent, for both instantaneous and integral readings, and (5) steps (2-4) occurring in real-time. |
| FILED | Thursday, January 30, 2020 |
| APPL NO | 16/776656 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/20 (20130101) Original (OR) Class G01T 1/023 (20130101) G01T 3/06 (20130101) Electric Digital Data Processing G06F 17/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11182774 | Boyd et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Daniel A. Boyd (Arlington, Virginia); Kelli L. Biegger (McLean, Virginia); Chang Ellison (Arlington, Virginia); Brandon P. Gutierrez (Burke, Virginia); Jason Lim (Alexandria, Virginia) |
| ABSTRACT | In an example involving a transaction conducted between a first party using a user mobile-identification-credential device (UMD) and a second party using a relying party system (RPS), RPS receives a request from UMD for transfer of an item, requests identification information of the first party from UMD, receives, based on consent of the first party, some or all user ID information associated with a mobile identification credential (MIC) which UMD received from an authorizing party system (APS), receives verification of the received user ID information, uses the verified user ID information to verify or not verify an identity of the first party, grants the request to transfer the item in exchange for payment or another item to be transferred from the first party to the second party when the identity of the first party is verified, and denies the request when the identity of the first party is not verified. |
| FILED | Thursday, March 18, 2021 |
| APPL NO | 17/205856 |
| ART UNIT | 2887 — Optics |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 20/326 (20200501) G06Q 20/347 (20130101) Original (OR) Class G06Q 20/3224 (20130101) G06Q 20/3226 (20130101) G06Q 20/3674 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11180841 | Hosek et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Persimmon Technologies, Corp. (Wakefield, Massachusetts) |
| ASSIGNEE(S) | Persimmon Technologies Corporation (Wakefield, Massachusetts) |
| INVENTOR(S) | Martin Hosek (Lowell, Massachusetts); Sripati Sah (Wakefield, Massachusetts); Jayaraman Krishnasamy (Boxborough, Massachusetts) |
| ABSTRACT | A soft magnetic material comprises a plurality of iron-containing particles and an insulating layer on the iron-containing particles, the insulating layer comprising an oxide. The soft magnetic material is an aggregate of permeable micro-domains separated by insulation boundaries. |
| FILED | Thursday, January 16, 2020 |
| APPL NO | 16/744382 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/02 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 4/08 (20130101) Original (OR) Class C23C 4/129 (20160101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/24 (20130101) H01F 1/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11183175 | Larson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Clinc, Inc. (Ann Arbor, Michigan) |
| ASSIGNEE(S) | Clinc, Inc. (Ann Arbor, Michigan) |
| INVENTOR(S) | Stefan Larson (Ann Arbor, Michigan); Kevin Leach (Ann Arbor, Michigan); Michael A. Laurenzano (Ann Arbor, Michigan) |
| ABSTRACT | A system and method of implementing an intuitive search interface for tactically searching one or more annotated utterance corpora in a machine learning-based dialogue system includes identifying an utterance corpus query for searching one or more annotated utterance corpora of a machine learning-based dialogue system; interpreting the utterance corpus query by translating the utterance corpus query into one or more search expressions recognizable to an utterance sample retrieval program searchably interfacing with the one or more annotated utterance corpora of the machine learning-based dialogue system; retrieving one or more annotated utterance samples from the one or more annotated utterance corpora based on the interpretation of the utterance corpus query; and returning the one or more annotated utterance samples to an intuitive utterance corpus search interface. |
| FILED | Wednesday, February 17, 2021 |
| APPL NO | 17/178052 |
| ART UNIT | 2656 — Digital Audio Data Processing |
| CURRENT CPC | Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/16 (20130101) Original (OR) Class G10L 15/22 (20130101) G10L 15/063 (20130101) G10L 15/1822 (20130101) G10L 2015/223 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 11180779 | Atiyeh |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Regents for Oklahoma State University (Stillwater, Oklahoma) |
| ASSIGNEE(S) | The Board of Regents for Oklahoma State University (Stillwater, Oklahoma) |
| INVENTOR(S) | Hasan K. Atiyeh (Stillwater, Oklahoma) |
| ABSTRACT | Biocatalytic conversion systems and methods of producing and using same that have improved yields are disclosed. The systems and methods involve co-fermentation of sugars and gaseous substrates for alcohol, ketone, and/or organic acid production. The systems and methods may include biocatalytically converting at least one sugar substrate into at least one of alcohol, at least one ketone, and/or at least one organic acid. The systems and methods may further include biocatalytically converting gases that comprise CO2 and H2 to at least one alcohol and/or at least one organic acid, thereby adding extra revenue to biorefineries. |
| FILED | Thursday, April 12, 2018 |
| APPL NO | 16/604242 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 21/12 (20130101) C12M 23/58 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 1/22 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/16 (20130101) C12P 7/28 (20130101) C12P 7/52 (20130101) C12P 7/54 (20130101) C12P 7/065 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 11179500 | Boden et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Scott D. Boden (Atlanta, Georgia); Sreedhara Sangadala (Dallas, Georgia) |
| ASSIGNEE(S) | EMORY UNIVERSITY (Altanta, Georgia); The United States Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Scott D. Boden (Atlanta, Georgia); Sreedhara Sangadala (Dallas, Georgia) |
| ABSTRACT | This disclosure relates to compounds and compositions for forming bone and methods related thereto. In certain embodiments, the disclosure relates to methods of forming bone comprising implanting a bone graft composition comprising a growth factor such as BMP in a subject at a site of desired bone growth or enhancement in combination with a JAB1 blocker. |
| FILED | Thursday, February 23, 2012 |
| APPL NO | 13/980593 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/46 (20130101) A61L 27/46 (20130101) A61L 27/54 (20130101) Original (OR) Class A61L 2300/414 (20130101) A61L 2430/02 (20130101) A61L 2430/06 (20130101) Compositions of Macromolecular Compounds C08L 89/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 11179673 | Pavlish et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Midwest Energy Emissions Corp. (Lewis Center, Ohio) |
| ASSIGNEE(S) | Midwwest Energy Emission Corp. (Corsicana, Texas) |
| INVENTOR(S) | John H. Pavlish (East Grand Forks, Minnesota); Edwin S. Olson (Grand Forks, North Dakota); Michael J. Holmes (Thompson, North Dakota) |
| ABSTRACT | Various embodiments disclosed relate to sorbents for the oxidation and removal of mercury. The present invention includes removing mercury from a mercury-containing gas using a halide-promoted and optionally ammonium-protected sorbent that can include carbon sorbent, non-carbon sorbent, or a combination thereof. |
| FILED | Friday, December 22, 2017 |
| APPL NO | 15/853029 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/10 (20130101) B01D 53/64 (20130101) Original (OR) Class B01D 53/83 (20130101) B01D 2251/108 (20130101) B01D 2251/206 (20130101) B01D 2253/102 (20130101) B01D 2257/602 (20130101) B01D 2258/0283 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/04 (20130101) B01J 20/10 (20130101) B01J 20/12 (20130101) B01J 20/20 (20130101) B01J 20/027 (20130101) B01J 20/041 (20130101) B01J 20/043 (20130101) B01J 20/106 (20130101) B01J 20/223 (20130101) B01J 20/0262 (20130101) B01J 20/3416 (20130101) B01J 20/28004 (20130101) B01J 2220/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11183626 | Dyson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of Americas as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Rodger W. Dyson (Elyria, Ohio); Geoffrey A. Bruder (Parma Heights, Ohio) |
| ABSTRACT | A magnetostrictive alternator configured to convert pressure waves into electrical energy is provided. It should be appreciated that the magnetostrictive alternator may be combined in some embodiments with a Stirling engine to produce electrical power. The Stirling engine creates the oscillating pressure wave and the magnetostrictive alternator converts the pressure wave into electricity. In some embodiments, the magnetostrictive alternator may include aerogel material and magnetostrictive material. The aerogel material may be configured to convert a higher amplitude pressure wave into a lower amplitude pressure wave. The magnetostrictive material may be configured to generate an oscillating magnetic field when the magnetostrictive material is compressed by the lower amplitude pressure wave. |
| FILED | Wednesday, December 13, 2017 |
| APPL NO | 15/840704 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/113 (20130101) H01L 41/125 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Geospatial Intelligence Agency (NGA)
| US 11183774 | Kim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The MITRE Corporation (McLean, Virginia) |
| ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
| INVENTOR(S) | Jerry T. W. Kim (Fairfax, Virginia); Behrooz Fakhari (North Potomac, Maryland) |
| ABSTRACT | A transportable, resilient, high frequency system with a compact footprint is provided. The system may include a plurality of antenna elements arranged around a circle. A circular array provides a resilient radiation pattern that does not change based on the number of antennas in the array and is tolerant of errors in antenna placement. The gain of the system may be increased by increasing the number of antenna elements in the array to compensate for reduced efficiency of antenna elements having a radiating element with a length of less than half the wavelength of an operating frequency of the array. |
| FILED | Friday, May 31, 2019 |
| APPL NO | 16/428327 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 3/28 (20130101) H01Q 21/20 (20130101) Original (OR) Class H01Q 21/26 (20130101) H01Q 21/293 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 11180804 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Fei Chen (Cambridge, Massachusetts); Andrew C. Payne (Cambridge, Massachusetts); Jason D. Buenrostro (Cambridge, Massachusetts); Paul Reginato (Cambridge, Massachusetts); Edward Stuart Boyden (Chestnut Hill, Massachusetts); Shahar Alon (Cambridge, Massachusetts) |
| ABSTRACT | The present invention provides methods for analyzing polynucleotides such as genomic DNA. In some embodiments, the disclosure provides a method for preparing and amplifying a genomic DNA library in situ in a fixed biological sample. The method comprises treating a fixed biological sample with an insertional enzyme complex to produce tagged fragments of genomic DNA. The method further comprises circularizing the tagged fragments of genomic DNA. The method further comprises amplifying the tagged fragments of genomic DNA. |
| FILED | Tuesday, July 24, 2018 |
| APPL NO | 16/043950 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) C12N 15/1082 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) C12Q 1/6809 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 2525/155 (20130101) C12Q 2525/155 (20130101) C12Q 2525/191 (20130101) C12Q 2525/191 (20130101) C12Q 2525/301 (20130101) C12Q 2525/301 (20130101) C12Q 2531/125 (20130101) C12Q 2531/125 (20130101) C12Q 2543/101 (20130101) C12Q 2543/101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 11181520 | Yuan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Baohong Yuan (Arlington, Texas); Bingbing Cheng (Dallas, Texas); Mingyuan Wei (Arlington, Texas) |
| ABSTRACT | Methods of imaging described herein comprises disposing a first and second ultrasound-switchable fluorophore in an environment; exposing the environment to an ultrasound beam to create an activation region; disposing the first and/or second fluorophore within the activation region to switch the first and/or second fluorophore from an off state to an on state; exposing the environment to a beam of electromagnetic radiation; detecting a first photoluminescence signal at a first location within the environment, the photoluminescence signal comprising at least one of a first ultrasound fluorescence signal emitted by the first fluorophore, a first fluorescence signal emitted by the second fluorophore, and a background signal; correlating the first photoluminescence signal with a first reference signal to generate a correlation coefficient for the first location; and multiplying the first photoluminescence signal by the first correlation coefficient for the first location to generate a first modified photoluminescence signal for the first location. |
| FILED | Thursday, June 27, 2019 |
| APPL NO | 16/455157 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0071 (20130101) A61B 8/481 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 41/0028 (20130101) A61K 49/0034 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 33/542 (20130101) G01N 33/5091 (20130101) Original (OR) Class G01N 2201/06113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 11181004 | Sunnarborg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Amy M. Sunnarborg (Jupiter, Florida); Brendan J. Dugan (Weatogue, Connecticut) |
| ABSTRACT | A pass through passage assembly of a gas turbine engine includes a compartment wall located between a first compartment and a second compartment, and a wall opening in the compartment wall connecting the first compartment and the second compartment, the wall opening having a central axis. A passage insert extends from the first compartment to the second compartment. A seal plate is positioned at the second compartment and extends about the central axis such that the compartment wall is located between an insert flange and the seal plate. A backing plate is positioned and retained between seal plate and the compartment wall, with the seal plate, the backing plate, the compartment wall, and the passage insert defining a seal cavity therebetween. A rope seal is located in the seal cavity and is retained in the seal cavity by the backing plate, the seal plate and the passage insert. |
| FILED | Friday, February 07, 2020 |
| APPL NO | 16/785204 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/005 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/55 (20130101) Pistons; Cylinders; Sealings F16J 15/022 (20130101) F16J 15/028 (20130101) F16J 15/104 (20130101) F16J 15/0812 (20130101) F16J 15/0887 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11181607 | Henderson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Shawn Henderson (Waltham, Massachusetts); Jerry Hosterman (Waltham, Massachusetts); Steven Eslinger (Waltham, Massachusetts); Megan J. Roberts (Waltham, Massachusetts) |
| ABSTRACT | In a geolocation system, ancillary parameter values, i.e., those produced during the geolocation process but not directly related to the calculation of the geolocation, are recorded and stored. These “ancillary” parameter values include signal characterization data and secondary measurements produced in the calculation of the geolocation. These parameter values are processed, in one approach, with respect to a weighted matrix in order to determine a confidence or fidelity value of the determined geolocation. Confidence is an indication of the likelihood that the geolocation result produced is in fact the desired target and that the identified location has a reasonable degree of quality so as to be practical or accurate. |
| FILED | Thursday, September 19, 2019 |
| APPL NO | 16/576314 |
| ART UNIT | 2864 — Printing/Measuring and Testing |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/021 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, November 23, 2021.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2021/details-patents-20210427.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page