FedInvent™ Patents

Patent Details for Tuesday, December 07, 2021 

This page was updated on Tuesday, December 07, 2021 at 10:10 PM GMT

Department of Health and Human Services (HHS) 

US 11191459 Friedman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S) Paul A. Friedman (Rochester, Minnesota);  Michael J. Ackerman (Rochester, Minnesota);  Samuel J. Asirvatham (Rochester, Minnesota);  Itzhak Zachi Attia (Rochester, Minnesota);  Kevin E. Bennet (Rochester, Minnesota);  Charles J. Bruce (Ponte Verda, Florida);  John J. Dillon (Rochester, Minnesota);  Jennifer L. Dugan (Rochester, Minnesota);  Dorothy J. Ladewig (Mazeppa, Minnesota);  Virend K. Somers (Rochester, Minnesota)
ABSTRACT Systems, methods, and other techniques for estimating the level of an analyte present in a patient during a time interval using electrocardiogram (ECG) signals. The estimate can be improved using information about the patient's posture.
FILED Tuesday, September 12, 2017
APPL NO 16/332692
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/316 (20210101)
A61B 5/349 (20210101)
A61B 5/352 (20210101)
A61B 5/366 (20210101)
A61B 5/1116 (20130101)
A61B 5/6803 (20130101)
A61B 5/6893 (20130101)
A61B 5/6898 (20130101)
A61B 5/14546 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191474 Efimov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Washington University (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Igor R. Efimov (Wildwood, Missouri);  Valentin I. Krinski (Villeneuve Loubet, France);  Vladmir P. Nikolski (St. Anthony, Minnesota)
ABSTRACT A method for extinguishing a cardiac arrhythmia utilizes destructive interference of the passing of the reentry wave tip of an anatomical reentry through a depolarized region created by a relatively low voltage electric field in such a way as to effectively unpin the anatomical reentry. Preferably, the relatively low voltage electric field is defined by at least one unpinning shock(s) that are lower than an expected lower limit of vulnerability as established, for example, by a defibrillation threshold test. By understanding the physics of the electric field distribution between cardiac cells, the method permits the delivery of an electric field sufficient to unpin the core of the anatomical reentry, whether the precise or estimated location of the reentry is known or unknown and without the risk of inducting ventricular fibrillation. A number of embodiments for performing the method are disclosed.
FILED Monday, December 23, 2019
APPL NO 16/725538
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/318 (20210101) Original (OR) Class
A61B 5/363 (20210101)
A61B 5/7239 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/3627 (20130101)
A61N 1/3906 (20130101)
A61N 1/3925 (20130101)
A61N 1/3987 (20130101)
A61N 1/39622 (20170801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191519 Waag et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) HABICO, Inc. (Honeoye Falls, New York)
ASSIGNEE(S) Habico, Inc. (Honey Falls, New York)
INVENTOR(S) Robert C. Waag (Buffalo, New York);  Jeffrey P. Astheimer (Honeoye Falls, New York)
ABSTRACT A device, system, and method for volumetric ultrasound imaging is described. The device and system include an array of transducer elements grouped in triangular planar facets and substantially configured in the shape of a hemisphere to form a cup-shaped volumetric imaging region within the cavity of the hemisphere, A plurality of data-acquisition assemblies are connected to the transducers, which are configured to collect ultrasound signals received from the transducers and transmit image data to a network of processors that are configured to construct a volumetric image of an object within the imaging region based on the image data received from the data-acquisition assemblies.
FILED Tuesday, August 04, 2015
APPL NO 15/501792
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 8/08 (20130101)
A61B 8/14 (20130101)
A61B 8/15 (20130101)
A61B 8/406 (20130101)
A61B 8/483 (20130101)
A61B 8/0825 (20130101) Original (OR) Class
A61B 8/4281 (20130101)
A61B 8/4494 (20130101)
A61B 8/5207 (20130101)
A61B 8/5269 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 15/8915 (20130101)
G01S 15/8929 (20130101)
G01S 15/8959 (20130101)
G01S 15/8977 (20130101)
G01S 15/8993 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191667 Santa Maria et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Peter Santa Maria (Redwood City, California);  Brian Hsueh (Pacifica, California);  Brian Kannard (Mountain View, California);  Ritu Lal (Palo Alto, California);  Abhinav Ramani (Herndon, Virginia);  John Paderi (San Francisco, California)
ABSTRACT A method for maintaining and/or increasing body temperature of a patient may involve delivering heat to a first location on a limb of the patient, delivering heat to a second location on the limb, apart from the first location, and applying intermittent compression to a third location on the limb, located between the first location and the second location. A device for maintaining and/or increasing body temperature of a patient may include a sleeve for positioning over at least part of one of the patient's limbs, first and second heat delivery members coupled with the sleeve, and an intermittent compression member coupled with the sleeve between the first and second heat delivery members.
FILED Tuesday, March 13, 2018
APPL NO 15/919953
ART UNIT 3785 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 7/02 (20130101) Original (OR) Class
A61F 7/03 (20130101)
A61F 2007/023 (20130101)
A61F 2007/0042 (20130101)
A61F 2007/0043 (20130101)
A61F 2007/0045 (20130101)
A61F 2007/0047 (20130101)
A61F 2007/0055 (20130101)
A61F 2007/0065 (20130101)
A61F 2007/0086 (20130101)
A61F 2007/0088 (20130101)
A61F 2007/0091 (20130101)
A61F 2007/0226 (20130101)
A61F 2007/0239 (20130101)
A61F 2007/0268 (20130101)
A61F 2007/0288 (20130101)

Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body
A61H 9/00 (20130101)
A61H 9/005 (20130101)
A61H 9/0057 (20130101)
A61H 9/0078 (20130101)
A61H 9/0092 (20130101)
A61H 39/04 (20130101)
A61H 2201/02 (20130101)
A61H 2201/0103 (20130101)
A61H 2201/164 (20130101)
A61H 2201/165 (20130101)
A61H 2201/0184 (20130101)
A61H 2201/0207 (20130101)
A61H 2201/0214 (20130101)
A61H 2201/0228 (20130101)
A61H 2201/0242 (20130101)
A61H 2201/0278 (20130101)
A61H 2201/501 (20130101)
A61H 2201/1619 (20130101)
A61H 2201/1635 (20130101)
A61H 2201/5007 (20130101)
A61H 2201/5097 (20130101)
A61H 2209/00 (20130101)
A61H 2230/50 (20130101)
A61H 2230/505 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/36042 (20130101)
A61N 7/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191724 He et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
APPLICANT(S) BRANDEIS UNIVERSITY (Waltham, Massachusetts)
ASSIGNEE(S) BRANDEIS UNIVERSITY (Waltham, Massachusetts)
INVENTOR(S) Hongjian He (Waltham, Massachusetts);  Bing Xu (Newton, Massachusetts)
ABSTRACT The present invention relates to a branched peptide that includes a first peptide chain and a second peptide chain having its C-terminal amino acid covalently linked to a sidechain of an amino acid residue of the first peptide chain, wherein the first peptide chain includes a plurality of aromatic amino acids and, optionally, an aromatic group linked to an amino terminus of the first peptide chain; and the second peptide chain includes a plurality of hydrophilic amino acids and an enzyme cleavage site. Pharmaceutical compositions containing the branched peptide and one or more therapeutic agents in an aqueous medium are disclosed, where the branched peptides form micelle structures in the aqueous medium. Methods of using the pharmaceutical composition to deliver therapeutic agents, and for treating various disease conditions are also described.
FILED Tuesday, September 18, 2018
APPL NO 16/648295
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/1075 (20130101) Original (OR) Class
A61K 31/704 (20130101)
A61K 47/42 (20130101)
A61K 47/6907 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 7/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191727 Graham et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The USA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Barney S. Graham (Rockville, Maryland);  Masaru Kanekiyo (Chevy Chase, Maryland);  Hadi M. Yassine (Boyds, Maryland)
ABSTRACT Novel, nanoparticle-based vaccines are provided that elicit an immune response to a broad range of infectious agents, such as influenza viruses. The nanoparticles comprise a heterogeneous population of fusion proteins, each comprising a monomeric subunit of a self-assembly protein, such as ferritin, joined to one or more immunogenic portions of a protein from an infectious agent, such as influenza virus. The fusion proteins self-assemble to form nanoparticles that display a heterogeneous population of immunogenic portions on their surface. When administered to an individual, such nanoparticles elicit an immune response to different strains, types, subtypes and species with in the same taxonomic family. Thus, such nanoparticles can be used to vaccinate an individual against infection by different Types, subtypes and/or strains of infectious agents. Also provided are specific fusion proteins, nucleic acid molecules encoding such fusion proteins and methods of using nanoparticles of the invention to vaccinate individuals.
FILED Thursday, December 31, 2015
APPL NO 15/540898
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/167 (20130101) Original (OR) Class
A61K 39/12 (20130101)
A61K 39/145 (20130101)
A61K 2039/70 (20130101)
A61K 2039/575 (20130101)
A61K 2039/6031 (20130101)
A61K 2039/6068 (20130101)
A61K 2039/6075 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2760/16134 (20130101)
C12N 2760/16171 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191732 Slusher et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
INVENTOR(S) Barbara S. Slusher (Baltimore, Maryland);  Anne Le (Baltimore, Maryland);  Takashi Tsukamoto (Ellicott City, Maryland)
ABSTRACT Currently available glutaminase inhibitors are generally poorly soluble, metabolically unstable, and/or require high doses, which together reduce their efficacy and therapeutic index. These can be formulated into nanoparticles and delivered safely and effectively for treatment of pancreatic cancer and other glutamine addicted cancers. Studies demonstrate that nanoparticle delivery of BPTES, relative to use of BPTES alone, can be safely administered and provides dramatically improved tumor drug exposure, resulting in greater efficacy. GLS inhibitors can be administered in higher concentrations with sub-100 nm nanoparticles, since the nanoparticles package the drug into “soluble” colloidal nanoparticles, and the nanoparticles deliver higher drug exposure selectively to the tumors due to the enhanced permeability and retention (EPR) effect. These factors result in sustained drug levels above the IC50 within the tumors for days, providing significantly enhanced efficacy compared to unencapsulated drug.
FILED Monday, April 20, 2020
APPL NO 16/853276
ART UNIT 1699 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/5146 (20130101)
A61K 9/5153 (20130101) Original (OR) Class
A61K 31/337 (20130101)
A61K 31/337 (20130101)
A61K 31/433 (20130101)
A61K 31/433 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Heterocyclic Compounds
C07D 285/135 (20130101)
C07D 417/12 (20130101)
C07D 417/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191743 Chang
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Dignity Health (Phoenix, Arizona)
ASSIGNEE(S)
INVENTOR(S) Yongchang Chang (Glendale, Arizona)
ABSTRACT Various embodiments disclosed herein include methods of modulating the function of Zinc Activated Cation Channel (ZACN) in a subject comprising: administering to the subject a pharmaceutically effective dosage of ATP, a purinergic compound, red or blue dye, heparin or heparin analog, desipramine, reboxetine, and/or tomoxetine; and modulating the function of ZACN in the subject. Various embodiments disclosed herein also include methods of treating a disease in a subject comprising: administering to the subject a pharmaceutically effective dosage of a compound capable of modulating the function of the Zinc Activated Cation Channel (ZACN), and treating the disease.
FILED Wednesday, January 11, 2017
APPL NO 16/068814
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/41 (20130101)
A61K 31/55 (20130101)
A61K 31/55 (20130101)
A61K 31/138 (20130101)
A61K 31/138 (20130101)
A61K 31/185 (20130101) Original (OR) Class
A61K 31/185 (20130101)
A61K 31/365 (20130101)
A61K 31/365 (20130101)
A61K 31/727 (20130101)
A61K 31/727 (20130101)
A61K 31/5375 (20130101)
A61K 31/5375 (20130101)
A61K 31/5415 (20130101)
A61K 31/7076 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/24 (20180101)
A61P 35/00 (20180101)

Peptides
C07K 14/705 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101)
C12Q 1/6886 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191745 Tiet et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) CITY OF HOPE (Duarte, California)
ASSIGNEE(S) CITY OF HOPE (Duarte, California)
INVENTOR(S) Pamela Tiet (Pasadena, California);  Jacob Berlin (Monrovia, California)
ABSTRACT Disclosed herein, inter alia, are nanoparticle compositions (e.g., silica nanoparticles) including insoluble drug nanocrystals and methods of using the same for treating cancer.
FILED Friday, February 02, 2018
APPL NO 16/483212
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/14 (20130101)
A61K 31/337 (20130101) Original (OR) Class
A61K 47/24 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 977/773 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191750 Sharp et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S) THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Zelton Dave Sharp (San Antonio, Texas);  Randy Strong (San Antonio, Texas);  Paul Hasty (San Antonio, Texas);  Carolina Livi (San Antonio, Texas);  Arlan Richardson (San Antonio, Texas)
ABSTRACT Disclosed are methods and compositions for the treatment or prevention of intestinal polyps or prevention of cancer in a patient who has been identified as being at risk for developing intestinal polyps or intestinal cancer. The disclosed methods and compositions include rapamycin, a rapamycin analog, or another such inhibitor of the target of rapamycin (TOR).
FILED Monday, June 29, 2020
APPL NO 16/915506
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5138 (20130101)
A61K 31/192 (20130101)
A61K 31/192 (20130101)
A61K 31/415 (20130101)
A61K 31/415 (20130101)
A61K 31/436 (20130101) Original (OR) Class
A61K 31/436 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191752 Palczewski et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio);  UNIVERSITY OF PITTSBURGH (Pittsburgh, Pennsylvania)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio);  UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
INVENTOR(S) Krzysztof Palczewski (Cleveland, Ohio);  Yuanyuan Chen (Cleveland, Ohio)
ABSTRACT This application relates to compounds and methods of treating retinal degeneration associated with inherited rhodopsin mutations in the ocular tissue of a subject. The retinal degeneration, can include, for example, macular degeneration, a including age-related macular degeneration, Stargardt disease, and retinitis pigmentosa. The retinitis pigmentosa can include autosomal dominate retinitis pigmentosa associated with a P23H RHO mutation. A method of treating retinal degeneration in a subject includes administering to the subject a therapeutically effective amount of a compound of formula (I), wherein the compound of formula (I) acts as a chaperone of rhodopsin.
FILED Monday, April 30, 2018
APPL NO 16/609162
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/365 (20130101)
A61K 31/381 (20130101)
A61K 31/4402 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 29/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191754 Tavis et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Saint Louis University (St. Louis, Missouri)
ASSIGNEE(S) Saint Louis University (St. Louis, Missouri)
INVENTOR(S) John Edwin Tavis (Kirkwood, Missouri);  Lynda Anne Morrison (Webster Groves, Missouri);  Marvin Meyers (Wentzville, Missouri)
ABSTRACT The present disclosure relates to identification of inhibitors of hepatitis and herpesvirus replication including compounds of the formula:
wherein the variables are as defined herein. Also provided are methods of treatment using agents so identified.
FILED Tuesday, August 06, 2019
APPL NO 16/533204
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 31/52 (20130101)
A61K 31/122 (20130101)
A61K 31/513 (20130101)
A61K 31/522 (20130101)
A61K 31/662 (20130101)
A61K 31/675 (20130101)
A61K 31/4375 (20130101)
A61K 31/4412 (20130101) Original (OR) Class
A61K 31/7072 (20130101)
A61K 31/7076 (20130101)
A61K 38/212 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/22 (20180101)

Acyclic or Carbocyclic Compounds
C07C 50/28 (20130101)
C07C 2601/18 (20170501)

Heterocyclic Compounds
C07D 213/89 (20130101)
C07D 471/04 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)

Enzymes
C12Y 301/26004 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191755 Gudas et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Cornell University (Ithaca, New York)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) Lorraine J Gudas (New York, New York);  Xiao-Han Tang (Staten Island, New York)
ABSTRACT The invention provides compositions and methods for providing a cardioprotective effect in a subject. Specifically, the invention provides compositions and methods for treating cardiovascular ailments, for example, ischemia/reperfusion (I/R) injury, cardiac arrhythmias, oxidative stress, or cardiac failure by administering a retinoic acid receptor-beta (RARβ) agonist.
FILED Thursday, June 14, 2018
APPL NO 16/008946
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/192 (20130101)
A61K 31/426 (20130101)
A61K 31/4436 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/06 (20180101)
A61P 9/10 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191763 Garcia Lerma et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Jose Gerardo Garcia Lerma (Decatur, Georgia);  Ivana Mabel Massud (Atlanta, Georgia);  Walid M. Heneine (Atlanta, Georgia)
ABSTRACT Disclosed is the use of a nucleoside reverse transcriptase inhibitor, a nucleotide reverse transcriptase inhibitor, and an integrase inhibitor after exposure to a potential human immunodeficiency virus (HIV) infection to inhibit or prevent an HIV infection. In some embodiments, a pharmacologically effective amount of emtricitabine (FTC), a pharmacologically effective amount of tenofovir alafenamide (TAF) or tenofovir disproxil fumarate (TDF), a pharmacologically effective amount of the integrase inhibitor elvitegravir (EVG), and optionally cobistat (COBI) are used to inhibit or prevent an HIV infection, wherein these agents are administered only after a potential exposure to HIV. In specific non-limiting examples, only one or two doses of the anti-retroviral viral agents are administered to a subject after the potential exposure to HIV.
FILED Monday, March 19, 2018
APPL NO 16/494696
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/47 (20130101)
A61K 31/513 (20130101) Original (OR) Class
A61K 31/675 (20130101)
A61K 31/5377 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/18 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191773 Kahne et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts);  Ohio State Innovation Foundation (Columbus, Ohio)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts);  The Ohio State University (Columbus, Ohio)
INVENTOR(S) Daniel E. Kahne (Cambridge, Massachusetts);  Michael D. Mandler (Cambridge, Massachusetts);  Vadim Baidin (Cambridge, Massachusetts);  Natividad Ruiz (Columbus, Ohio)
ABSTRACT This invention features new compositions and methods that are useful in treating a host with a Gram-negative bacterial infection. Combination therapies comprising an aminocoumarin compound and a polymyxin compound are disclosed, including certain combinations that exhibit synergistic effects. Furthermore, aminocoumarin compounds are described having altered inhibition of DNA gyrase in Gram-negative bacteria and/or the ability to target the transport proteins responsible for assembling lipopolysaccharide in the outer membrane of Gram-negative bacteria.
FILED Monday, July 16, 2018
APPL NO 16/631717
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7048 (20130101)
A61K 31/7056 (20130101) Original (OR) Class
A61K 38/12 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191774 Mitragotri et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Samir Mitragotri (Lexington, Massachusetts);  Marta Broto (Barcelona, Spain);  Kathryn M. Camacho (Los Angeles, California);  Stefano Menegatti (Raleigh, North Carolina)
ABSTRACT Compounds and pharmaceutical formulations containing these compounds are described. Also described are methods of making and using the compounds. The compounds include nucleobases, nucleobase analogues, or combinations thereof. In one embodiment, a nucleobase analogue is combined with doxorubicin and encapsulated within a liposome for use in inhibiting or preventing the growth of cancer cells. Further described are pharmaceutical compositions containing two or more therapeutically active agents encapsulated within a vesicle, such as a liposome, wherein the molar ratio of the agents provides a synergistic therapeutic effect.
FILED Wednesday, November 23, 2016
APPL NO 15/779232
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/1273 (20130101)
A61K 31/506 (20130101)
A61K 31/513 (20130101)
A61K 31/7072 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191778 Azhdarinia et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S) THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Ali Azhdarinia (Houston, Texas);  Sukhen C. Ghosh (Houston, Texas);  Nathaniel L. Wilganowski (Houston, Texas);  Eva M. Sevick-Muraca (Houston, Texas)
ABSTRACT In some aspects, the present disclosure provides compositions comprising an N4-based MMC ligand, a cell targeting group, and a fluorophore or a therapeutic compound comprising a formula:
wherein the variables are as defined herein. In some embodiments, these compositions may be used in the imaging techniques or in the treatment of a disease or disorder such as cancer.
FILED Friday, July 26, 2019
APPL NO 16/523044
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 33/02 (20130101) Original (OR) Class
A61K 33/24 (20130101)
A61K 33/243 (20190101)
A61K 33/244 (20190101)
A61K 38/16 (20130101)
A61K 39/385 (20130101)
A61K 39/395 (20130101)
A61K 49/0021 (20130101)
A61K 2039/5152 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191785 Lagasse
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
ASSIGNEE(S) UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
INVENTOR(S) Eric Lagasse (Pittsburgh, Pennsylvania)
ABSTRACT The present invention relates to methods and compositions for transplanting non-lymphoid tissues into lymphoid organs. It may be used to cultivate organ tissues including for the purpose of supplementing or reconstituting organ function. Tissues that may be propagated in this manner include but are not limited to lung, kidney, thyroid, intestine, and brain.
FILED Monday, July 27, 2015
APPL NO 14/810064
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/22 (20130101)
A61K 35/26 (20130101) Original (OR) Class
A61K 35/30 (20130101)
A61K 35/38 (20130101)
A61K 35/39 (20130101)
A61K 35/42 (20130101)
A61K 35/55 (20130101)
A61K 2035/122 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191805 Watnick
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts)
ASSIGNEE(S) CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts)
INVENTOR(S) Randolph S. Watnick (Newton, Massachusetts)
ABSTRACT Provided herein are cyclic prosaposin peptides and compositions and uses thereof. Exemplary uses include use in the treatment of cancer or in the treatment of inflammatory diseases or disorders.
FILED Tuesday, April 21, 2020
APPL NO 16/854792
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/08 (20130101)
A61K 38/12 (20130101) Original (OR) Class

Peptides
C07K 7/64 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191811 Karsenty et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Gerard Karsenty (New York, New York);  Paula Mera (New York, New York);  Emilio Arteaga-Solis (Brooklyn, New York)
ABSTRACT Methods and compositions for treating frailty in mammals, preferably humans, are provided. The methods generally involve modulation of the OST-PTP signaling pathway or the PTP-1B signaling pathway involving gamma-carboxylase and osteocalcin, e.g., by administration of undercarboxylated/uncarboxylated osteocalcin. The methods comprise alleviating at least one of: muscle wasting or a lung disorder while also alleviating at least one of: a metabolic disorder, a male reproductive disorder, or a cognitive disorder.
FILED Thursday, November 19, 2015
APPL NO 15/528085
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 38/22 (20130101) Original (OR) Class
A61K 38/39 (20130101)

Peptides
C07K 14/78 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191821 Seder et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Robert Seder (Chevy Chase, Maryland);  Geoffrey Lynn (Baltimore, Maryland)
ABSTRACT Embodiments of a novel platform for delivering a peptide antigen to a subject to induce an immune response to the peptide antigen are provided. For example, nanoparticle polyplexes are provided that comprise a polymer linked to a peptide conjugate by an electrostatic interaction. The conjugate comprises a peptide antigen linked to a peptide tag through an optional linker. An adjuvant may be included in the nanoparticle polyplex, linked to either the polymer or the conjugate, or admixed with the nanoparticles. The nanoparticle polyplex can be administered to a subject to induce an immune response to the peptide antigen.
FILED Monday, February 27, 2017
APPL NO 16/079972
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 39/0011 (20130101) Original (OR) Class
A61K 39/39 (20130101)
A61K 39/001102 (20180801)
A61K 2039/60 (20130101)
A61K 2039/555 (20130101)
A61K 2039/6093 (20130101)
A61K 2039/55555 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191823 Abraham et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts);  DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts)
ASSIGNEE(S) CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts);  DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts)
INVENTOR(S) Jonathan Abraham (Boston, Massachusetts);  Stephen Harrison (Boston, Massachusetts);  Kai Wucherpfennig (Boston, Massachusetts)
ABSTRACT The invention generally provides compositions and methods of treating or preventing an arenavirus infection, using an agent that inhibits binding of an arenavirus glycoprotein 1 (GP1) polypeptide to transferrin receptor 1 (TfR1). The invention also provides methods of designing or identifying therapeutic agents that bind to or target a GP1 receptor-binding site (RBS) to inhibit arenavirus attachment to a cell, and therapeutic agents identified using the methods.
FILED Wednesday, June 07, 2017
APPL NO 16/308318
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101) Original (OR) Class
A61K 39/39516 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)

Peptides
C07K 14/08 (20130101)
C07K 16/10 (20130101)
C07K 2317/21 (20130101)
C07K 2317/33 (20130101)
C07K 2317/55 (20130101)
C07K 2317/76 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
C12N 2760/10022 (20130101)
C12N 2760/10031 (20130101)
C12N 2760/10043 (20130101)
C12N 2760/16134 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/53 (20130101)
G01N 33/56983 (20130101)
G01N 2333/08 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 15/00 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191841 Webber et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Matthew J. Webber (Cambridge, Massachusetts);  Eric Andrew Appel (Palo Alto, California);  Robert S. Langer (Newton, Massachusetts);  Daniel Griffith Anderson (Framingham, Massachusetts)
ABSTRACT The modification of biomolecules, small molecules, and other agents of via conjugation of excipients, tags, or labels is of great importance. For example, the modification of therapeutic agents can confer improved stability, solubility, duration of action, or pharmacological properties. Supramolecular chemistry utilizes specific, directional, reversible, non-covalent molecular recognition motifs in order to achieve organization of molecules, and can be used to complex tags to agents of interest (e.g., insulin, glucagon, antibodies). The present invention provides useful supramolecular complexes wherein an agent of interest is specifically bound to a host via non-covalent interactions, and wherein the host is conjugated to a tag. The present invention also provides methods and compounds useful in preparing supramolecular complexes, and methods of treating diseases using the supramolecular complexes.
FILED Thursday, October 06, 2016
APPL NO 15/765585
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/26 (20130101)
A61K 38/28 (20130101)
A61K 47/34 (20130101)
A61K 47/60 (20170801)
A61K 47/545 (20170801) Original (OR) Class
A61K 47/6889 (20170801)

Heterocyclic Compounds
C07D 519/00 (20130101)

Peptides
C07K 14/62 (20130101)
C07K 14/605 (20130101)
C07K 16/2896 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191850 Strongin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Portland State University (Portland, Oregon)
ASSIGNEE(S) Portland State University (Portland, Oregon)
INVENTOR(S) Robert M Strongin (Portland, Oregon);  Martha Sibrian-Vazquez (Portland, Oregon);  Lei Wang (Camas, Washington);  Jorge O. Escobedo Cordova (Portland, Oregon);  Mark A. Lowry (Portland, Oregon)
ABSTRACT Molecular probes for detecting and imaging pancreatic cancer are disclosed. The probes are modified benzoxanthene fluorophores, which are selectively taken up by pancreatic cancer cells, such as pancreatic ductal adenocarcinoma cells. Embodiments of the disclosed probes are useful for pancreatic cancer detection, therapeutic monitoring, and/or image-guided surgery.
FILED Tuesday, May 23, 2017
APPL NO 16/304109
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0012 (20130101)
A61K 49/006 (20130101)
A61K 49/0043 (20130101) Original (OR) Class

Heterocyclic Compounds
C07D 311/86 (20130101)
C07D 491/16 (20130101)

Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes
C09B 11/16 (20130101)
C09B 11/22 (20130101)
C09B 11/24 (20130101)

Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 11/06 (20130101)
C09K 2211/1007 (20130101)
C09K 2211/1018 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191871 Alsberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) Eben Alsberg (Cleveland, Ohio);  Rui Tang (Solon, Ohio)
ABSTRACT A composition includes a plurality of particulate coated hydrogel microparticles, each of the microparticles including a hydrogel inner core and a particulate shell defined by a plurality of solid nanoparticles, the particulate shell inhibiting aggregation of the microparticles in an aqueous medium and being permeable to allow release of agents from the hydrogel inner core.
FILED Monday, April 01, 2019
APPL NO 16/371806
ART UNIT 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5084 (20130101)
A61K 47/02 (20130101)
A61K 47/42 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/24 (20130101) Original (OR) Class
A61L 27/36 (20130101)
A61L 27/54 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)
B82Y 40/00 (20130101)

Peptides
C07K 14/78 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 3/075 (20130101)
C08J 2389/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0068 (20130101)
C12N 2533/54 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191872 Kyriakides et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) YALE UNIVERSITY (New Haven, Connecticut)
ASSIGNEE(S) Yale University (New Haven, Connecticut)
INVENTOR(S) Themis Kyriakides (Branford, Connecticut);  Nina Kristofik (Wallingford, Connecticut)
ABSTRACT The present invention relates to novel compositions and methods for reducing or eliminating the thrombogenicity of a graft by modifying the graft with a cell-derived extracellular matrix lacking thrombospondin-2 (TSP2-null ECM) to render it non-thrombogenic when transplanted to a subject in need thereof. The invention also provides a method for improving the biocompatibility of a medical device or an implant by modifying the medical device or implant with a cell-derived TSP2-null ECM, whereby the medical device or implant is rendered non-thrombogenic and pro-migratory.
FILED Tuesday, April 25, 2017
APPL NO 16/095815
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/28 (20130101) Original (OR) Class
A61L 27/34 (20130101)
A61L 27/54 (20130101)
A61L 27/3633 (20130101)
A61L 29/085 (20130101)
A61L 31/10 (20130101)
A61L 33/18 (20130101)
A61L 33/128 (20130101)
A61L 2300/42 (20130101)
A61L 2300/606 (20130101)
A61L 2430/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191875 Baker et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah);  UNIVERSITY AT BUFFALO (Amherst, New York)
ASSIGNEE(S) UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah);  UNIVERSITY AT BUFFALO (Amherst, New York)
INVENTOR(S) Olga Baker (Salt Lake City, Utah);  Kihoon Nam (Salt Lake City, Utah);  Pedro Lei (Salt Lake City, Utah);  Stelios Andreadis (Salt Lake City, Utah)
ABSTRACT The invention is directed to a composition comprising a fibrin hydrogel conjugated to peptides of laminin-111 (L1) and methods for repairing damaged salivary tissue using the composition.
FILED Tuesday, September 19, 2017
APPL NO 16/326326
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/64 (20170801)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/52 (20130101) Original (OR) Class
A61L 27/225 (20130101)
A61L 2430/22 (20130101)
A61L 2430/40 (20130101)

Peptides
C07K 14/75 (20130101)
C07K 14/78 (20130101)
C07K 19/00 (20130101)
C07K 2319/50 (20130101)
C07K 2319/60 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191886 Karimov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Non-Profit Organization (NPO)
The Cleveland Clinic Foundation
APPLICANT(S) THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio)
ASSIGNEE(S) THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio)
INVENTOR(S) Jamshid Karimov (Cleveland Hts., Ohio);  Kiyotaka Fukamachi (Mayfield Hts., Ohio);  Ray Dessoffy (Parma, Ohio)
ABSTRACT A device for minimizing obstruction in a medical device that carries fluids includes a housing defining a channel configured to receive and secure a section of the medical device such that the section of the medical device extends coaxially with a central longitudinal axis of the channel. The device also includes components supported in the housing, including a motor, wherein the components are configured to be operated to impart motion to the housing and the attached medical device. The motion is configured to produce oscillatory motion of a frequency sufficient to concentrate shear stresses in a fluid boundary layer adjacent an inner wall of the medical device. The housing and the components supported in the housing are configured and arranged so that a device center of mass lies along or near the longitudinal axis of the channel.
FILED Friday, March 02, 2018
APPL NO 15/910399
ART UNIT 3781 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 2090/701 (20160201)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 1/04 (20130101)
A61M 1/842 (20210501) Original (OR) Class
A61M 25/00 (20130101)
A61M 25/02 (20130101)
A61M 2025/0019 (20130101)
A61M 2205/103 (20130101)
A61M 2205/106 (20130101)
A61M 2205/8206 (20130101)
A61M 2206/16 (20130101)
A61M 2209/10 (20130101)
A61M 2210/101 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191958 Tai
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Changfeng Tai (Wexford, Pennsylvania)
ABSTRACT Provided herein are methods and devices useful for inhibiting or treating urological conditions, such as overactive bladder (OAB) symptoms including bladder overactivity, urinary frequency, urinary urgency, urinary incontinence, interstitial cystitis (IC), urinary retention, and pelvic pain; gastrointestinal conditions, such as fecal incontinence, irritable bowel syndrome (IBS), and constipation; and sexual conditions, such as premature ejaculation, erectile disorder, and female sexual arousal disorder by non-invasive transcutaneous electrical stimulation of the foot.
FILED Monday, May 13, 2019
APPL NO 16/410206
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/36007 (20130101) Original (OR) Class
A61N 1/36034 (20170801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11192109 Ben-Yakar et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Adela Ben-Yakar (Austin, Texas);  Navid Ghorashian (Sunnyvale, California);  Sertan Kutal Gökçe (Austin, Texas);  Sam Xun Guo (Katy, Texas);  William Neil Everett (Cedar Park, Texas);  Frederic Bourgeois (Lynn, Massachusetts)
ABSTRACT Microfluidic devices for the rapid and automated processing of sample populations are provided. Described are multiplexer microfluidic devices configured to serially deliver a plurality of distinct sample populations to a sample processing element rapidly and automatically, without cross-contaminating the distinct sample populations. Also provided are microfluidic sample processing elements that can be used to rapidly and automatically manipulate and/or interrogate members of a sample population. The microfluidic devices can be used to improve the throughput and quality of experiments involving model organisms, such as C. elegans.
FILED Wednesday, July 18, 2018
APPL NO 16/038415
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502715 (20130101)
B01L 3/502738 (20130101)
B01L 3/502761 (20130101) Original (OR) Class
B01L 2200/027 (20130101)
B01L 2200/0652 (20130101)
B01L 2200/0668 (20130101)
B01L 2300/0816 (20130101)
B01L 2300/0861 (20130101)
B01L 2300/0867 (20130101)
B01L 2300/0877 (20130101)
B01L 2400/06 (20130101)
B01L 2400/0487 (20130101)
B01L 2400/0655 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/4833 (20130101)
G01N 2333/43534 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11192850 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Zhong-Yin Zhang (West Lafayette, Indiana);  Kasi Viswanatharaju Ruddraraju (West Lafayette, Indiana)
ABSTRACT The present disclosure relates to novel N-aryl oxamic acid based inhibitors for Mycobacterium tuberculosis protein tyrosine phosphatase B (mPTPB), and to the method of making and using the novel N-aryl oxamic acid based inhibitors. More specifically, compounds provided in this disclosure can be used to inhibit Mycobacterium tuberculosis protein tyrosine phosphatase B (mPTPB) and to treat a patient having a Tuberculosis disease.
FILED Monday, February 01, 2021
APPL NO 17/163650
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/06 (20180101)

Acyclic or Carbocyclic Compounds
C07C 235/74 (20130101) Original (OR) Class
C07C 317/14 (20130101)

Heterocyclic Compounds
C07D 215/48 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11192859 Schmidt et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) NEW YORK UNIVERSITY (New York, New York);  UNIVERSITY OF ALBANY (Albany, New York)
ASSIGNEE(S)
INVENTOR(S) Ann Marie Schmidt (Franklin Lakes, New Jersey);  Ravichandran Ramasamy (Ardsley, New York);  Alexander Shekhtman (Glenmont, New York);  Vivek Rai (Allahabad, India);  Michaele B. Manigrasso (New York, New York)
ABSTRACT Quinoline compounds are disclosed that have a formula represented by the following:
and wherein Cy, R1, R4a, R4b, and n are as described herein. The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, diabetes complications, inflammation, and neurodegeneration, obesity, cancer, ischemia/reperfusion injury, cardiovascular disease and other diseases related to RAGE activity.
FILED Tuesday, April 18, 2017
APPL NO 16/094270
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/47 (20130101)
A61K 31/4709 (20130101)
A61K 31/5377 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 29/00 (20180101)

Heterocyclic Compounds
C07D 215/12 (20130101)
C07D 215/14 (20130101) Original (OR) Class
C07D 215/52 (20130101)
C07D 401/04 (20130101)
C07D 401/06 (20130101)
C07D 401/14 (20130101)
C07D 413/14 (20130101)
C07D 498/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11192866 Myers et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Andrew G. Myers (Boston, Massachusetts);  Mark G. Charest (Belle Mead, New Jersey);  Christian D. Lerner (Binningen, Switzerland);  Jason D. Brubaker (Cheshire, Connecticut);  Dionicio R. Siegel (New York, New York)
ABSTRACT The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the tetracyclines in human and veterinary medicine has led to resistance among many organisms previously susceptible to tetracycline antibiotics. The modular synthesis of tetracyclines and tetracycline analogs described provides an efficient and enantioselective route to a variety of tetracycline analogs and polycyclines previously inaccessible via earlier tetracycline syntheses and semi-synthetic methods. These analogs may be used as anti-microbial agents or anti-proliferative agents in the treatment of diseases of humans or other animals.
FILED Monday, May 20, 2019
APPL NO 16/417458
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 231/10 (20130101)
C07C 237/26 (20130101)

Heterocyclic Compounds
C07D 209/56 (20130101)
C07D 209/58 (20130101)
C07D 213/56 (20130101)
C07D 221/18 (20130101)
C07D 235/02 (20130101)
C07D 237/26 (20130101)
C07D 239/70 (20130101)
C07D 241/38 (20130101)
C07D 261/20 (20130101) Original (OR) Class
C07D 263/52 (20130101)
C07D 277/30 (20130101)
C07D 277/56 (20130101)
C07D 277/64 (20130101)
C07D 277/66 (20130101)
C07D 307/77 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11192869 Verkman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Eye Institute (NEI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Alan S. Verkman (San Francisco, California);  Marc H. Levin (San Francisco, California);  Onur Cil (San Francisco, California)
ABSTRACT Provided herein are compounds that activate CFTR and methods for treating constipation, dry eye disorders or other diseases and disorders.
FILED Monday, October 28, 2019
APPL NO 16/666278
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 1/10 (20180101)
A61P 27/04 (20180101)

Heterocyclic Compounds
C07D 285/135 (20130101) Original (OR) Class
C07D 417/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11192871 Canney et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) Temple University-Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania)
ASSIGNEE(S) Temple University-Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania)
INVENTOR(S) Daniel J. Canney (Ambler, Pennsylvania);  Benjamin E. Blass (Eagleville, Pennsylvania);  Rong Gao (Eugene, Oregon);  Magid Abou-Gharbia (Exton, Pennsylvania)
ABSTRACT Pharmaceutical compositions of the invention comprise functionalized lactone derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity.
FILED Thursday, December 12, 2019
APPL NO 16/712711
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 307/28 (20130101)
C07D 307/33 (20130101) Original (OR) Class
C07D 307/94 (20130101)
C07D 405/06 (20130101)
C07D 405/12 (20130101)
C07D 405/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11192889 Coller et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Rockefeller University (New York, New York);  ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York)
ASSIGNEE(S) THE ROCKEFELLER UNIVERSITY (New York, New York)
INVENTOR(S) Barry S. Coller (New York, New York);  Marta Filizola (Riverdale, New York);  Michael Andrew Foley (New York, New York)
ABSTRACT Tetrahydronaphthyridines of formula
are disclosed. These compounds selectively inhibit αVβ3 without activating the αVβ3 receptor. They are useful for treating osteoporosis, acute myelogenous leukemia, sickle cell disease, focal segmental glomerulosclerosis, fibrosis, supravalvular aortic stenosis associated with Williams syndrome, tumors expressing αVβ3, tumor metastasis, bone resorption, T-cell lymphoma, retinal disease, age-related macular degeneration, diabetic retinitis, and herpes simplex virus infection. They may also be used for inhibiting tumor angiogenesis.
FILED Wednesday, July 05, 2017
APPL NO 16/315093
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 471/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11192893 Kapoor et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Rockefeller University (New York, New York)
ASSIGNEE(S) The Rockefeller University (New York, New York)
INVENTOR(S) Tarun M. Kapoor (New York, New York);  Moriteru Asano (Tokushima, Japan);  Kazuyoshi Aso (Kanagawa, Japan);  Michael A. Foley (New York, New York);  Yoshiyuki Fukase (Edgewater, New Jersey);  Hideki Furukawa (Chigasaki, Japan);  Yashuhiro Hirata (Kanagawa, Japan);  Sachie Takashima (Kanagawa, Japan);  Tomohiro Okawa (Kanagawa, Japan);  Yuta Tanaka (Kanagawa, Japan);  Yayoi Yoshitomi (Kanagawa, Japan)
ABSTRACT Compounds of formula:
are useful as antitumor agents. In these compounds, R10 is (a) (C1-C10) hydrocarbyl, (C1-C10)halohydrocarbyl, (C1-C6)hydroxyalkyl, or
or R10 is (b)
in which Q and A are linkers and Ar is optionally substituted monocyclic or bicyclic aryl or heteroaryl.
FILED Friday, May 18, 2018
APPL NO 16/614621
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Heterocyclic Compounds
C07D 487/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11192903 Sato et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of Americans, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Noriko Sato (Potomac, Maryland);  Haitao Wu (Rockville, Maryland);  Gary L. Griffiths (North Potomac, Maryland);  Peter L. Choyke (Rockville, Maryland)
ABSTRACT The invention provides a method of preparing a 89Zr-oxine complex of the formula
The invention also provides a method of labeling a cell with the 89Zr-oxine complex and a method for detecting a biological cell in a subject comprising administering the 89Zr-oxine complex to the subject.
FILED Friday, December 20, 2019
APPL NO 16/723601
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 51/0478 (20130101)
A61K 51/1203 (20130101)

General Methods of Organic Chemistry; Apparatus Therefor
C07B 59/004 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 7/003 (20130101) Original (OR) Class

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/16 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/60 (20130101)
G01N 2458/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11192929 Harris et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
NIH Office of the Director (NIHOD)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Reuben S. Harris (St. Paul, Minnesota);  Hideki Aihara (Roseville, Minnesota)
ABSTRACT Materials and methods for using modified Cas9-APOBEC fusion polypeptides for targeted modification of specific DNA sequences are provided herein.
FILED Friday, December 08, 2017
APPL NO 15/836598
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 14/4703 (20130101) Original (OR) Class
C07K 2319/80 (20130101)
C07K 2319/85 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/102 (20130101)
C12N 15/1082 (20130101)
C12N 2310/20 (20170501)

Enzymes
C12Y 302/02027 (20130101)
C12Y 305/04005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11192942 DeLisa et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) CORNELL UNIVERSITY (Ithaca, New York)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) Matthew DeLisa (Ithaca, New York);  Jeffrey Varner (Ithaca, New York);  Alyse Portnoff (Ithaca, New York)
ABSTRACT The present invention relates to an isolated chimeric molecule comprising a degradation domain including a eukaryotic U-box motif and a targeting domain capable of immunospecifically directing the degradation domain to a substrate where the targeting domain is heterologous to the degradation domain. A linker couples the degradation domain to the targeting domain. Also disclosed are compositions as well as methods of treating a disease, substrate silencing, screening agents for therapeutic efficacy against a disease, and methods of screening for disease biomarkers.
FILED Tuesday, April 09, 2019
APPL NO 16/379309
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 16/00 (20130101)
C07K 16/18 (20130101) Original (OR) Class
C07K 2319/00 (20130101)
C07K 2319/50 (20130101)
C07K 2319/95 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/93 (20130101)

Enzymes
C12Y 603/02019 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11192958 Molldrem et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Jeffrey Molldrem (Houston, Texas);  Anna Sergeeva (Houston, Texas)
ABSTRACT The specification describes the sequences for antibodies that recognize the HLA-A2-restricted peptide PR-1 in the context of HLA presentation on the surface of cancer cells. Use of these antibodies in the diagnosis and treatment of cancer and immune-related diseases are also provided.
FILED Tuesday, February 13, 2018
APPL NO 15/895782
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/00 (20130101)
A61K 45/06 (20130101)
A61K 47/6851 (20170801)
A61K 47/6871 (20170801)

Peptides
C07K 16/30 (20130101)
C07K 16/40 (20130101) Original (OR) Class
C07K 16/2833 (20130101)
C07K 16/3061 (20130101)
C07K 2317/24 (20130101)
C07K 2317/32 (20130101)
C07K 2317/34 (20130101)
C07K 2317/71 (20130101)
C07K 2317/73 (20130101)
C07K 2317/92 (20130101)
C07K 2317/567 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57488 (20130101)
G01N 2333/96433 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11192978 Lam et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Kit S. Lam (Davis, California);  Yuanpei Li (Davis, California);  Juntao Luo (Jamesville, New York);  Kai Xiao (Sacramento, California)
ABSTRACT The present invention provides amphiphilic telodendrimers that aggregate to form nanocarriers characterized by a hydrophobic core and a hydrophilic exterior. The nanocarrier core may include amphiphilic functionality such as cholic acid or cholic acid derivatives, and the exterior may include branched or linear poly(ethylene glycol) segments. Nanocarrier cargo such as hydrophobic drugs and other materials may be sequester in the core via non-covalent means or may be covalently bound to the telodendrimer building blocks. Telodendrimer structure may be tailored to alter loading properties, interactions with materials such as biological membranes, and other characteristics.
FILED Friday, September 14, 2018
APPL NO 16/131644
ART UNIT 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/1075 (20130101)
A61K 9/1271 (20130101)
A61K 31/337 (20130101)
A61K 45/06 (20130101)
A61K 47/28 (20130101)
A61K 47/34 (20130101)
A61K 47/60 (20170801)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 65/329 (20130101)
C08G 65/3348 (20130101) Original (OR) Class
C08G 83/004 (20130101)

Compositions of Macromolecular Compounds
C08L 71/02 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/2982 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193110 Allbritton et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S) Nancy Allbritton (Chapel Hill, North Carolina);  Yuli Wang (Cary, North Carolina);  Christopher Sims (Chapel Hill, North Carolina);  Scott Magness (Chapel Hill, North Carolina);  Scott Bultman (Chapel Hill, North Carolina)
ABSTRACT A method of making a live cell construct is carried out by: (a) providing a non-cellular support having a top surface and a bottom surface, (b) contacting live undifferentiated cells to the non-cellular support, and then (c) propagating a gastrointestinal epithelial cell monolayer on said top surface. In some embodiments, the live cells in the monolayer include: (i) undifferentiated cells (e.g., stem or progenitor cells); and (ii) optionally, but in some embodiments preferably, differentiated cells (e.g., enterocytes, Paneth cells, enteroendocrine cells, tuft cells, microcells, intra-epithelial lymphocytes, and/or goblet cells). Constructs formed by such methods and methods of using the same (e.g., in high through-put screening) are also described.
FILED Friday, January 29, 2016
APPL NO 15/545456
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0679 (20130101)
C12N 5/0697 (20130101) Original (OR) Class
C12N 2501/11 (20130101)
C12N 2501/15 (20130101)
C12N 2501/415 (20130101)
C12N 2501/727 (20130101)
C12N 2501/998 (20130101)
C12N 2501/999 (20130101)
C12N 2513/00 (20130101)
C12N 2533/54 (20130101)
C12N 2533/90 (20130101)
C12N 2535/00 (20130101)
C12N 2537/10 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/08 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 2500/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193111 Steinmetz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) Nicole F. Steinmetz (Cleveland, Ohio);  Amy M. Wen (Cleveland, Ohio)
ABSTRACT Virus particle multimers and methods of making and using such virus particle multimer are described. Virus particle multimers are constructed by preparing a plurality of asymmetrically functionalized virus particles bearing one or more functional groups and contacting the asymmetrically functionalized virus particles with a first linker molecule that reacts with the functional groups to form a virus particle multimer that includes a plurality of asymmetrically functionalized virus particles connected by the linker molecule. The asymmetrically functionalized virus particles are typically prepared by attaching the virus particles to a support surface to allow asymmetrical functionalization to be introduced.
FILED Friday, December 27, 2013
APPL NO 14/761444
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101) Original (OR) Class
C12N 2770/32023 (20130101)
C12N 2770/32051 (20130101)
C12N 2770/32142 (20130101)
C12N 2810/856 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193118 Dorfman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Kevin David Dorfman (Edina, Minnesota);  Pranav Agrawal (Minnepolis, Minnesota)
ABSTRACT A molecular filter that may include a substrate. The substrate may define a first channel, a second channel, at least one slit fluidically coupling the first channel to the second channel, at least one inlet port fluidically coupled to the first channel, at least one recovery port fluidically coupled to the first channel, at least one purge port fluidically coupled to the first channel, and at least one filtrate port fluidically coupled to the second channel. A respective cross-sectional area of each respective slit of the at least one slit in a plane perpendicular to a long axis of the respective slit is smaller than a cross-sectional area of the first channel in a plane perpendicular to a long axis of the first channel.
FILED Wednesday, September 19, 2018
APPL NO 16/135737
ART UNIT 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1017 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/4077 (20130101)
G01N 2001/4088 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193127 Terns et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia)
ASSIGNEE(S) UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia)
INVENTOR(S) Rebecca M. Terns (Athens, Georgia);  Michael P. Terns (Athens, Georgia);  Joshua R. Elmore (Knoxville, Tennessee)
ABSTRACT Provided herein is a programmable RNA-activated DNA endonuclease activity associated with a Cmr complex. In one embodiment, the enzyme is a general double-stranded DNA endonuclease. Also provided is a programmable RNA endonuclease activity associated with a Cmr complex. In one embodiment, a Cmr2 protein present in a Cmr complex includes a mutation that reduces RNA-activated DNAse activity of the Cmr complex. In one embodiment, a Cmr4 protein present in a Cmr complex includes a mutation that reduces the RNase activity of the Cmr complex. Compositions including components of a Cmr complex and a CRISPR-RNA, and an optional activating RNA, are provided. Also provided are methods for using the compositions, and genetically engineered cells that include components of a Cmr complex and a CRISPR-RNA, and an optional activating RNA.
FILED Friday, January 06, 2017
APPL NO 16/065236
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 14/195 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/20 (20130101)
C12N 9/22 (20130101)
C12N 15/111 (20130101)
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/10 (20130101)
C12N 2310/20 (20170501)
C12N 2510/00 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101)
C12Q 1/6806 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193141 Dever et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California)
INVENTOR(S) Daniel P. Dever (Stanford, California);  Rasmus O. Bak (Stanford, California);  Ayal Hendel (Stanford, California);  Waracharee Srifa (Stanford, California);  Matthew H. Porteus (Stanford, California)
ABSTRACT In certain aspects, the present invention provides methods for inducing a stable gene modification of a target nucleic acid via homologous recombination in a primary cell, such as a primary blood cell and/or a primary mesenchymal cell. In certain other aspects, the present invention provides methods for enriching a population of genetically modified primary cells having targeted integration at a target nucleic acid. The methods of the present invention rely on the introduction of a DNA nuclease such as a Cas polypeptide and a homologous donor adeno-associated viral (AAV) vector into the primary cell to mediate targeted integration of the target nucleic acid. Also provided herein are methods for preventing or treating a disease in a subject in need thereof by administering to the subject any of the genetically modified primary cells or pharmaceutical compositions described herein to prevent the disease or ameliorate one or more symptoms of the disease.
FILED Wednesday, March 21, 2018
APPL NO 15/927750
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7115 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 7/00 (20180101)

Peptides
C07K 14/805 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0635 (20130101)
C12N 5/0636 (20130101)
C12N 5/0665 (20130101)
C12N 9/22 (20130101)
C12N 15/113 (20130101)
C12N 15/907 (20130101) Original (OR) Class
C12N 15/8645 (20130101)
C12N 2310/20 (20170501)
C12N 2310/311 (20130101)
C12N 2310/313 (20130101)
C12N 2310/3125 (20130101)
C12N 2750/14143 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193155 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland)
ASSIGNEE(S) UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland)
INVENTOR(S) Lai-Xi Wang (Ellicott City, Maryland);  Chao Li (College Park, Maryland);  Shilei Zhu (Halethorpe, Maryland)
ABSTRACT The present invention provides for novel fucosidase mutants that server as fuco-ligases for core fucosylation of a range of biological glycopeptides and glycoproteins including intact therapeutic antibodies. Several mutants with mutation at the general acid/base residue E274 of the Lactobacillus casei α1,6-fucosidase, including E274A, E274S, and E274G, were able to efficiently fucosylate a wide variety of complex N-glycopeptides and intact glycoproteins. The site specific mutants enable the transfer of fucose to a core GlcNAc-Asn residue and useful for drug delivery and vaccine development.
FILED Thursday, August 10, 2017
APPL NO 16/323355
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 2319/21 (20130101)
C07K 2319/50 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/2402 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 21/005 (20130101) Original (OR) Class

Enzymes
C12Y 302/01127 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193945 Paczesny
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (Indianapolis, Indiana)
ASSIGNEE(S) Indiana Research and Technology Corporation (Indianapolis, Indiana)
INVENTOR(S) Sophie Paczesny (Indianapolis, Indiana)
ABSTRACT Disclosed are biomarker panels for evaluating subjects at risk of sinusoidal obstruction syndrome (SOS) early after hematopoietic stem cell transplantation (HSCT). In particular, the present disclosure relates to the use of one or more of ST2, ANG2, L-Ficolin, HA, and VCAM1 for prognosing, diagnosing, and/or treating SOS.
FILED Tuesday, February 04, 2020
APPL NO 16/781407
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/14546 (20130101)

Peptides
C07K 14/78 (20130101)
C07K 14/7056 (20130101)
C07K 14/7155 (20130101)
C07K 14/70542 (20130101)
C07K 16/2836 (20130101)
C07K 16/2851 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 30/72 (20130101)
G01N 33/53 (20130101)
G01N 33/68 (20130101)
G01N 33/577 (20130101)
G01N 33/6893 (20130101) Original (OR) Class
G01N 2333/78 (20130101)
G01N 2333/4724 (20130101)
G01N 2333/70503 (20130101)
G01N 2400/40 (20130101)
G01N 2800/08 (20130101)
G01N 2800/52 (20130101)
G01N 2800/085 (20130101)
G01N 2800/245 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193947 Zhang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Cedars-Sinai Medical Center (Los Angeles, California)
ASSIGNEE(S) CEDARS-SINAI MEDICAL CENTER (Los Angeles, California)
INVENTOR(S) Shenyan Zhang (Beijing, China PRC);  Koen Raedschelders (Venice, California);  Jennifer Van Eyk (Los Angeles, California)
ABSTRACT Described herein are methods for assessing the risk of cardiovascular disease in a subject in need thereof by detecting the presence of one or more cleavage products of the one or more natriuretic peptides over a period of time, wherein the presence of one or more cleavage products is indicative of an increased risk of the subject developing cardiovascular disease. Provided herein are compositions and kits comprising a non-natural natriuretic peptide comprising one or more D-amino acids. Also provided herein are methods of diagnosing a subject for a disease and treating the subject for the disease, wherein the method comprises the use of a non-natural natriuretic peptide comprising one or more D-amino acids.
FILED Thursday, October 04, 2018
APPL NO 16/152336
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/74 (20130101) Original (OR) Class
G01N 2570/00 (20130101)
G01N 2800/32 (20130101)
G01N 2800/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11194290 Brooker et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) CellOptic, Inc. (Rockville, Maryland)
ASSIGNEE(S) CELLOPTIC, INC. (Rockville, Maryland)
INVENTOR(S) Gary Brooker (Rockville, Maryland);  Nisan Siegel (Silver Spring, Maryland)
ABSTRACT Techniques to improve image quality in holography utilizing lenses made from materials with non-quantized anisotropic electromagnetic properties, such as birefringent materials, to advantageously split an incoming beam of light into two coincident beams with different focal lengths that interfere with one another and thus create holograms free of electro-optical or pixelated devices are disclosed. Corresponding systems, methods and apparatuses are described.
FILED Monday, May 13, 2019
APPL NO 16/410365
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 5/3083 (20130101)

Holographic Processes or Apparatus
G03H 1/041 (20130101) Original (OR) Class
G03H 1/0443 (20130101)
G03H 1/0866 (20130101)
G03H 2001/0445 (20130101)
G03H 2001/0452 (20130101)
G03H 2223/17 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11195280 Harrison et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institutes of Health Clinical Center (NIHCL)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, As Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Adam Patrick Harrison (Bethesda, Maryland);  Ziyue Xu (Reston, Virginia);  Le Lu (Poolesville, Maryland);  Ronald M. Summers (Potomac, Maryland);  Daniel Joseph Mollura (Chevy Chase, Maryland)
ABSTRACT Methods include processing image data through a plurality of network stages of a progressively holistically nested convolutional neural network, wherein the processing the image data includes producing a side output from a network stage m, of the network stages, where m>1, based on a progressive combination of an activation output from the network stage m and an activation output from a preceding stage m−1. Image segmentations are produced. Systems include a 3D imaging system operable to obtain 3D imaging data for a patient including a target anatomical body, and a computing system comprising a processor, memory, and software, the computing system operable to process the 3D imaging data through a plurality of progressively holistically nested convolutional neural network stages of a convolutional neural network.
FILED Friday, June 08, 2018
APPL NO 16/620464
ART UNIT 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/7267 (20130101)
A61B 6/032 (20130101)
A61B 6/50 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/084 (20130101)
G06N 3/0454 (20130101)
G06N 3/0481 (20130101)

Image Data Processing or Generation, in General
G06T 7/0016 (20130101) Original (OR) Class
G06T 7/174 (20170101)
G06T 2207/10081 (20130101)
G06T 2207/20081 (20130101)
G06T 2207/20084 (20130101)
G06T 2207/30061 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 30/40 (20180101)
G16H 50/50 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11195281 Schoess et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Jeffrey Norman Schoess (Howard Lake, Minnesota);  David G Armstrong (Studio City, California)
ASSIGNEE(S)
INVENTOR(S) Jeffrey Norman Schoess (Howard Lake, Minnesota);  David G Armstrong (Studio City, California)
ABSTRACT A method for determining healing progress of a tissue disease state includes receiving a thermal image of a target wound area from a thermal imaging system, processing the thermal image to construct an isotherm map of at least one selected area, determining a thermal index value from the isotherm map, correlating the wound thermal index value with a reference thermal index value representative of an injury-free state.
FILED Thursday, August 27, 2020
APPL NO 17/005257
ART UNIT 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0008 (20130101)
A61B 5/015 (20130101)
A61B 5/0077 (20130101)
A61B 5/445 (20130101)
A61B 5/7267 (20130101)
A61B 2576/02 (20130101)

Image Data Processing or Generation, in General
G06T 7/0016 (20130101) Original (OR) Class
G06T 2207/10048 (20130101)
G06T 2207/30088 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 30/40 (20180101)
G16H 40/67 (20180101)
G16H 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11195596 Meuleman
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Wouter Meuleman (Cambridge, Massachusetts)
ABSTRACT Embodiments of techniques for analyzing one or more genomic regions of a genome of an organism. Data about a genomic region may be analyzed to determine an information content of the genomic region, which may indicate an amount of information provided by the genomic region. The data about the genomic region may be or include data identifying a chromatin state for the genomic region. A chromatin state may be one of a set of chromatin states that each define a different set of one or more chromatin characteristics. Chromatin characteristics may be structural and/or functional features of genomic regions. A chromatin state of a genomic region may be determined from, and describe, the genomic region such that when a genomic region has a set of one or more chromatin characteristics, a chromatin state associated with that combination of one or more chromatin characteristics is identified for the genomic region.
FILED Friday, January 29, 2016
APPL NO 15/547240
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 20/00 (20190201)
G16B 20/20 (20190201)
G16B 30/00 (20190201) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11195615 Harley et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) Zeriscope, Inc. (Mount Pleasant, South Carolina)
ASSIGNEE(S) Zeriscope, Inc. (Mount Pleasant, South Carolina)
INVENTOR(S) William G. Harley (Mount Pleasant, South Carolina);  Ronald Ettore Acierno (Houston, Texas)
ABSTRACT A multimodal data acquisition and communication system and method for distributed management of in vivo exposure (IVE) therapy. An exemplary system, method, and apparatus according to certain aspects of the present disclosure may include a patient interface comprising (a) one or more sensors configured to collect quantitative (e.g., physiological data) and qualitative data (e.g., video/audio data) from a patient user during an IVE therapy session, and (b) a mobile computing device, such as a smartphone, comprising a mobile software application configured to establish a data transfer interface with the one or more sensors and provide a graphical user interface to the patient user. The mobile computing device may be communicatively engaged with a cloud-based server over a wireless communications network to enable real-time collection, communication, storage and analysis of IVE data and bi-directional audio/video communication with at least one clinician client device.
FILED Monday, August 10, 2020
APPL NO 16/989681
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0022 (20130101)
A61B 5/024 (20130101)
A61B 5/0077 (20130101)
A61B 5/369 (20210101)
A61B 5/389 (20210101)
A61B 5/0531 (20130101)
A61B 5/0816 (20130101)
A61B 5/1112 (20130101)
A61B 5/1118 (20130101)
A61B 5/02055 (20130101)
A61B 5/7264 (20130101)
A61B 5/7465 (20130101)
A61B 2560/0252 (20130101)
A61B 2562/029 (20130101)
A61B 2562/0219 (20130101)
A61B 2562/0271 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 10/60 (20180101)
G16H 20/70 (20180101)
G16H 40/67 (20180101) Original (OR) Class
G16H 50/20 (20180101)
G16H 50/70 (20180101)
G16H 80/00 (20180101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE48842 Verkman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Library of Medicine (NLM)
Extramural Programs (NLMEP)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Alan S. Verkman (San Francisco, California);  David S. Snyder (Davis, California)
ABSTRACT Provided herein are benzopyrimido-pyrrolo-oxazine-dione (BPO) compounds and pyrimido-pyrrolo-quinoxalinedione (PPQ) compounds, and compositions comprising these compounds, that inhibit cystic fibrosis transmembrane conductance regulator (CFTR) mediated ion transport and that are useful for treating diseases and disorders associated with aberrantly increased CFTR chloride channel activity, such as polycystic kidney disease and secretory diarrheas. The compounds and compositions comprising the compounds described herein may be used for inhibiting expansion or preventing formation of cysts in persons who have polycystic kidney disease.
FILED Tuesday, January 14, 2020
APPL NO 16/742778
ART UNIT 3991 — Central Reexamination Unit (Chemical)
CURRENT CPC
Heterocyclic Compounds
C07D 487/14 (20130101)
C07D 498/14 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 11191309 McCusker et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Secretary of the Army (SECARMY)
APPLICANT(S) U.S. Government as Represented by the Secretary of the Army (Natick, Massachusetts)
ASSIGNEE(S) U.S. Government as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Kathryn L McCusker (Uxbridge, Massachusetts);  Robert E Drown (Wilmington, Massachusetts);  Matthew J Hurley (Framingham, Massachusetts);  Alfredo Lujan (Suffolk, Massachusetts)
ABSTRACT A knee pad assembly includes a protective member, a hard shell member and a hinge member connecting the protective member and the hard shell member. A first end of the hard shell member is connected to the hinge member. A second end of the hard shell member opposing the first end has an upper lip member and a lower lip member, the upper lip member and the lower lip member defining a recessed member that extends from one side of second end of the hard shell member to an other side of the second end of the hard shell member.
FILED Tuesday, April 16, 2019
APPL NO 16/385064
ART UNIT 3732 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Outerwear; Protective Garments; Accessories
A41D 13/065 (20130101)
A41D 13/0575 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191493 Hu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
United States Air Force (USAF)
APPLICANT(S) The University of Maryland, Baltimore (Baltimore, Maryland)
ASSIGNEE(S) The University of Maryland, Baltimore (Baltimore, Maryland)
INVENTOR(S) Fu-Ming Hu (Ellicott City, Maryland);  Colin Mackenzie (Pasadena, Maryland);  Shiming Yang (Halethrope, Maryland);  Hegang Chen (Ellicott City, Maryland)
ABSTRACT A method is provided for predicting that a patient will require a blood transfusion during a treatment. The method includes obtaining, on a processor, first data that indicates values for one or more parameters of a characteristic of a continuous photoplethysmographic (PPG) waveform collected during the treatment. The method further includes applying, on the processor, coefficients to the values for the one or more parameters. The method further includes determining, on the processor, second data that indicates a prediction that the patient will require the blood transfusion during the treatment based on applying the coefficients to the values for the one or more parameters. An apparatus is also provided for predicting that the patient will require the blood transfusion during the treatment.
FILED Thursday, February 28, 2019
APPL NO 16/288207
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0205 (20130101)
A61B 5/742 (20130101)
A61B 5/02042 (20130101)
A61B 5/02416 (20130101)
A61B 5/4836 (20130101)
A61B 5/7275 (20130101) Original (OR) Class
A61B 5/14551 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 20/40 (20180101)
G16H 50/20 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11192182 Wu
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Secretary of the Navy (SECNAV)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Chun-Hsien Wu (Louisville, Kentucky)
ABSTRACT A substrate for 3D printing using a cold spray technique. The substrate of the present invention has a porous surface with the size of pores smaller than approximately 24.4 times the mean particle size of feedstock powders for cold spray processing and larger than or equal to approximately 6.84 times the mean particle size. Due to no adhesion of a 3D-printed part to the porous regions of the substrate, the parts fabricated by cold spray can be easily removed from the porous substrate without cutting.
FILED Thursday, November 15, 2018
APPL NO 16/192434
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Casting of Metals; Casting of Other Substances by the Same Processes or Devices
B22D 23/003 (20130101)

Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 3/02 (20130101)
B22F 3/005 (20130101) Original (OR) Class
B22F 10/40 (20210101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
B33Y 40/00 (20141201)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 24/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11192261 Jackowski et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
United States Army (USA)
APPLICANT(S) Boston Dynamics, Inc. (Waltham, Massachusetts)
ASSIGNEE(S) Boston Dynamics, Inc. (Waltham, Massachusetts)
INVENTOR(S) Zachary Jackowski (Somerville, Massachusetts);  Kevin Blankespoor (Arlington, Massachusetts);  John Aaron Saunders (Arlington, Massachusetts);  Francis M. Agresti (Waltham, Massachusetts)
ABSTRACT Example methods and devices for touch-down detection for a robotic device are described herein. In an example embodiment, a computing system may receive a force signal due to a force experienced at a limb of a robotic device. The system may receive an output signal from a sensor of the end component of the limb. Responsive to the received signals, the system may determine whether the force signal satisfies a first threshold and determine whether the output signal satisfies a second threshold. Based on at least one of the force signal satisfying the first threshold or the output signal satisfying the second threshold, the system of the robotic device may provide a touch-down output indicating touch-down of the end component of the limb with a portion of an environment.
FILED Thursday, January 17, 2019
APPL NO 16/250458
ART UNIT 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 9/1694 (20130101)
B25J 13/081 (20130101)
B25J 13/085 (20130101) Original (OR) Class

Motor Vehicles; Trailers
B62D 57/032 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 901/01 (20130101)
Y10S 901/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11192612 Conner
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Secretary of the Navy (SECNAV)
APPLICANT(S) Robert Conner (Panama City, Florida)
ASSIGNEE(S) United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Robert Conner (Panama City, Florida)
ABSTRACT A minimally invasive method for attaching to a surface is provided. The method utilizes an attachment apparatus for non-penetrating mechanical attachment of components to a target surface. The apparatus includes a cartridge assembly and mounting assembly. Actuation of the cartridge assembly causes first and second exothermic reactants located between outer casing and the inner casing to come into contact and cause an exothermic reaction. This reaction liquefies a bonding material between the cartridge assembly and mounting assembly, allowing it to flow around the mounting assembly and onto a target surface creating a seal. Vacuum pressure will bind the mounting assembly to a target surface.
FILED Wednesday, August 31, 2016
APPL NO 15/252484
ART UNIT 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 65/483 (20130101)
B29C 66/00145 (20130101)

Ships or Other Waterborne Vessels; Equipment for Shipping
B63B 9/00 (20130101) Original (OR) Class
B63B 2221/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11192923 Alvarez
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
United States Army (USA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Theradaptive, Inc. (Frederick, Maryland)
ASSIGNEE(S) Theradaptive, Inc. (Frederick, Maryland)
INVENTOR(S) Luis Alvarez (Lexington, Massachusetts)
ABSTRACT Provided herein are beta-TCP binding sequences and chimeric polypeptides that include one or more beta-TCP binding sequences and a mammalian growth factor, compositions comprising any of these chimeric polypeptides (and optionally, beta-TCP), and methods of promoting bone or cartilage formulation, methods of replacing and/or repairing bone or cartilage, and methods of treating a bone fraction or bone loss that include administration of any of these compositions.
FILED Wednesday, June 03, 2020
APPL NO 16/892141
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/04 (20130101)
A61K 38/16 (20130101)
A61K 38/1875 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 19/00 (20180101)

Peptides
C07K 7/08 (20130101) Original (OR) Class
C07K 14/001 (20130101)
C07K 14/51 (20130101)
C07K 14/475 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11192967 Harvey et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Secretary of the Navy (SECNAV)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Benjamin G. Harvey (Ridgecrest, California);  Andrew Chafin (Ridgecrest, California);  Matthew C. Davis (Ridgecrest, California)
ABSTRACT A method for making thermosetting polyimides from resveratrol including converting resveratrol to trisaniline, reacting trisaniline with one or more dianhydride and thermosetting endcap to form amic acid, thermally imidizing amic acid to form polyimide oligomer, and cross-linking polyimide oligomer with heat and pressure to generate polyimide thermoset.
FILED Wednesday, June 05, 2019
APPL NO 16/431790
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/123 (20130101)

Acyclic or Carbocyclic Compounds
C07C 209/22 (20130101)
C07C 211/51 (20130101)
C07C 217/90 (20130101)

Heterocyclic Compounds
C07D 235/20 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 132/08 (20130101) Original (OR) Class

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 7/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193042 Claridge et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Shelley A. Claridge (Lafayette, Indiana);  Tyson C. Davis (Lafayette, Indiana)
ABSTRACT The present invention generally relates to a method for creating a chemically structured surface with structural elements as small as 1 nm, on a material that does not itself display a high degree of ordering, using thin molecular layers that minimize the material added through the coating. In particular, the present invention discloses a method for assembling a chemical pattern on a surface, comprising pattern elements with scales that can be as small as 1 nm, and then transferring that pattern to another substrate, on which the pattern would not form natively. In the described method, the patterned monolayer is comprised of polymerizable amphiphiles such as diyne phospholipids or diynoic acids, which are transferred from the ordering substrate using a transferring material such as poly(dimethylsiloxane).
FILED Tuesday, March 17, 2020
APPL NO 16/820786
ART UNIT 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Processes for Applying Fluent Materials to Surfaces, in General
B05D 1/286 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 191/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193149 Lynch et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
APPLICANT(S) DUKE UNIVERSITY (Durham, North Carolina)
ASSIGNEE(S) DUKE UNIVERSITY (Durham, North Carolina)
INVENTOR(S) Michael David Lynch (Durham, North Carolina);  Zhixia Ye (Raleigh, North Carolina)
ABSTRACT The present disclosure provides compositions and methods for rapid production of chemicals in genetically engineered microorganisms in a large scale. Also provided herein is a high-throughput metabolic engineering platform enabling the rapid optimization of microbial production strains. The platform, which bridges a gap between current in vivo and in vitro bio-production approaches, relies on dynamic minimization of the active metabolic network.
FILED Wednesday, October 23, 2019
APPL NO 16/661027
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/001 (20130101)
C12N 9/0006 (20130101)
C12N 9/0008 (20130101)
C12N 9/0016 (20130101)
C12N 9/0051 (20130101)
C12N 9/1025 (20130101)
C12N 15/746 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/42 (20130101) Original (OR) Class
C12P 13/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193153 Xuan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Feng Xuan (Boston, Massachusetts);  Jocelyn Yoshiko Kishi (Boston, Massachusetts);  Peng Yin (Brookline, Massachusetts)
ABSTRACT The present disclosure provides, in some embodiments, methods and compositions for exponential amplification of single- and double-stranded DNA under isothermal conditions.
FILED Monday, March 19, 2018
APPL NO 16/495721
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/34 (20130101) Original (OR) Class

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6853 (20130101)
C12Q 2531/119 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193551 Jahromi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Babak Haghpanah Jahromi (Irvine, California);  Lorenzo Valdevit (Irvine, California);  Jonathan Hopkins (Los Angeles, California)
ABSTRACT In one embodiment, a shape-reconfigurable structure includes a rigid base having first and second ends, a rigid first beam having a lateral end and a central end, the lateral end being connected to the first end of the base, and a rigid second beam having a lateral end and a central end, the lateral end of the second beam being connected to the second end of the base and the central end of the second beam being connected to the central end of the first beam, wherein the structure can be placed in an expanded orientation in which the first and second beams extend outward away from the base and a contracted orientation in which the first and second beams extend inward toward the base.
FILED Thursday, April 27, 2017
APPL NO 15/498648
ART UNIT 3633 — Static Structures, Supports and Furniture
CURRENT CPC
Springs; Shock-absorbers; Means for Damping Vibration
F16F 1/025 (20130101)
F16F 7/00 (20130101) Original (OR) Class
F16F 2230/34 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193558 Miller
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Picatinny Arsenal (PICA)
APPLICANT(S) Loc Performance, Inc. (Plymouth, Michigan)
ASSIGNEE(S) Loc Performance Products, LLC (Plymouth, Michigan)
INVENTOR(S) Scott C Miller (Troy, Michigan)
ABSTRACT A dual bidirectional input to single bidirectional output transmission (or gear box) comprising of unique gear ratios between each of the bidirectional inputs and the single, or common, bidirectional output is disclosed. The gear box has a gear train design with two bidirectional inputs and one (or common) bidirectional output. The device is configured to enable torque to be transmitted through either one or both of the bidirectional inputs to the bidirectional output. The gear train may be a constant mesh system which eliminates sliding splines, dog clutches or synchronizers to switch between operational modes. A locking feature/component/element allows the power or torque to be transmitted from a first bidirectional input to the common bidirectional output using a second bidirectional input as a fixed rotation reference. Similarly power or torque from the second bidirectional input to the common bidirectional output may use the first bidirectional input as a fixed rotation reference. The disclosure may also include a planetary gear set load combiner to cause both bidirectional inputs to transmit torque or power to the common output simultaneously. Additionally, the locking feature/component/element enables the transfer of torque from either inputs independently without back driving the other input.
FILED Thursday, May 02, 2019
APPL NO 16/401989
ART UNIT 3658 — Material and Article Handling
CURRENT CPC
Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles
B60K 6/365 (20130101)

Gearing
F16H 3/089 (20130101) Original (OR) Class
F16H 3/091 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193743 Blazek et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Secretary of the Navy (SECNAV)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Benjamin M. Blazek (Ridgecrest, California);  Lee R. Hardt (Ridgecrest, California)
ABSTRACT Embodiments are directed cook-off mitigation systems. As assembled, a munition fuzewell is torqued into the aft end of a munition. The fuzewell is hollow and has an inner and an outer surface. The hollow fuzewell is configured to release during cook-off. Release is assisted by employing a biased equivalent strength threaded release ring concentric about the fuzewell. The biased equivalent strength threaded release ring has a threaded inner surface and a threaded outer surface. The biased equivalent strength threaded release ring's threaded inner surface threadingly-engages with threads on the fuzewell's outer surface. A munition case is concentric about the biased equivalent strength threaded release ring.
FILED Thursday, June 04, 2020
APPL NO 16/892879
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 12/20 (20130101)
F42B 12/207 (20130101)
F42B 39/14 (20130101)
F42B 39/20 (20130101) Original (OR) Class

Ammunition Fuzes; Arming or Safety Means Therefor
F42C 19/02 (20130101)
F42C 19/04 (20130101)
F42C 19/0807 (20130101)
F42C 19/0838 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193745 Campbell et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Secretary of the Army (SECARMY)
APPLICANT(S) U.S. Government as Represented by the Secretary of the Army (Dover, New Jersey)
ASSIGNEE(S) The United States of America as Represented bv the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Daniel Campbell (Morristown, New Jersey);  Geraldine Reilly (Hackettstown, New Jersey)
ABSTRACT A single-point munition arming interface provides a more efficient approach to arming a canister-based munition. The single-point munition arming interface interfaces with electrically-initiated canister-based munitions. The arming interface locks and arms munitions in a baseplate system before initiation. The single-point munition arming interface includes a feature for removing the first safety in the munitions safe and arm device which is actuated upon insertion of the munition into the interface. The second step in the procedure is a user action which simultaneously locks the munition to the interface and completes the arming sequence by using a single mechanism to achieve both essential motions. The arming interface can be mechanically or electrically actuated allowing for remote activation which increases operator safety.
FILED Friday, May 08, 2020
APPL NO 16/869730
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 23/24 (20130101)

Ammunition Fuzes; Arming or Safety Means Therefor
F42C 15/40 (20130101) Original (OR) Class
F42C 15/184 (20130101)
F42C 15/196 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193746 Albrecht
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Secretary of the Navy (SECNAV)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Nicholas H. Albrecht (Ridgecrest, California)
ABSTRACT The embodiments are directed to methods of initiating insensitive explosive formulations. The disclosed methods include positioning a donor explosive pellet adjacent to an insensitive acceptor explosive pellet having a plurality of relative percent theoretical maximum density (TMD) zones. The insensitive acceptor explosive pellet is adjacent to an insensitive explosive fill. Upon donor explosive pellet initiation, the donor explosive pellet provides a shock stimulus to the insensitive acceptor explosive pellet, which initiates the insensitive acceptor explosive pellet, causing a detonation wave to be driven through the plurality of relative percent TMD zones and into the insensitive explosive fill.
FILED Wednesday, December 02, 2020
APPL NO 17/109663
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ammunition Fuzes; Arming or Safety Means Therefor
F42C 19/0815 (20130101) Original (OR) Class
F42C 19/0838 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193829 Shaltout et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of the Army (DOA)
Army Research Office (ARO)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Amr Mohammad E Shaltout (West Lafayette, Indiana);  Alexander V. Kildishev (West Lafayette, Indiana);  Vladimir M Shalaev (West Lafayette, Indiana);  Jingjing Liu (West Lafayette, Indiana)
ABSTRACT A circular dichroism spectrometer which comprises a metasurface. The metasurface has a plurality of anisotropic antennas configured to simultaneously spatially separate LCP and RCP spectral components from an incoming light beam. An optical detector array is included which detects the LCP and RCP spectral components. A transparent medium is situated between the metasurface and the optical detector array.
FILED Monday, July 20, 2020
APPL NO 16/932834
ART UNIT 2886 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/0224 (20130101)
G01J 3/0256 (20130101)
G01J 3/447 (20130101) Original (OR) Class
G01J 3/2803 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/19 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193834 Sanyal et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Surface Warfare Center (NSWC)
Secretary of the Navy (SECNAV)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Crane, Indiana)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Subrata Sanyal (Eastvale, California);  Joseph A. Fiordilino (Corona, California)
ABSTRACT The present invention relates to a system for measuring the power of electromagnetic radiation (EMR) using piezoelectric transducers (PZTs) and pyroelectric transducers (PRTs). According to an illustrative embodiment of the present disclosure, a target cell has a mirrored surface that can partially reflect and partially absorb EMR. Each target cell can include or be coupled to PZTs and PRTs. When incident EMR reflects off of targets cells, the reflected portion creates radiation pressure and the non-reflected portions creates heat. The PZTs convert the pressure into a first electric current, and the PRTs convert the heat into a second electric current. Measuring the first and/or second currents allows a user to calculate the original power of an EMR source. By utilizing multiple target cells placed in specially designed arrays, a user can calculate fluctuations of EMR power by time and location across the target cells.
FILED Thursday, June 11, 2020
APPL NO 16/898694
ART UNIT 2884 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 5/34 (20130101) Original (OR) Class
G01J 2005/345 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193928 Beshay et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Intelligent Optical Systems, Inc. (Torrance, California)
ASSIGNEE(S) Intelligent Optical Systems, Inc. (Torrance, California)
INVENTOR(S) Manal Beshay (Rancho Palos Verdes, California);  Janet L Jensen (Aberdeen, Maryland);  James M Cress (Aberdeen, Maryland)
ABSTRACT An unmanned vehicle operated autonomously or by remotely piloting incorporates an onboard camera which is affixed with clear tape coated with a chemical colorimetric sensor dye sensitive to chemical warfare agents. Chemical warfare agents are detected by visual review or autonomous measurement of sensor color changes while the unmanned vehicle travels through a region suspected of having chemical warfare agents present. In various implementations, the sensor output color changes may be visually monitored by a vehicle operator viewing the camera image from a remote location. In various embodiments, the detection of chemical warfare agents may be confirmed by processing the coated tape with a calibrated opto-electronic reader.
FILED Friday, June 12, 2020
APPL NO 16/900850
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/783 (20130101)
G01N 33/52 (20130101) Original (OR) Class
G01N 33/0057 (20130101)
G01N 2021/7756 (20130101)
G01N 2021/7759 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193947 Zhang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Cedars-Sinai Medical Center (Los Angeles, California)
ASSIGNEE(S) CEDARS-SINAI MEDICAL CENTER (Los Angeles, California)
INVENTOR(S) Shenyan Zhang (Beijing, China PRC);  Koen Raedschelders (Venice, California);  Jennifer Van Eyk (Los Angeles, California)
ABSTRACT Described herein are methods for assessing the risk of cardiovascular disease in a subject in need thereof by detecting the presence of one or more cleavage products of the one or more natriuretic peptides over a period of time, wherein the presence of one or more cleavage products is indicative of an increased risk of the subject developing cardiovascular disease. Provided herein are compositions and kits comprising a non-natural natriuretic peptide comprising one or more D-amino acids. Also provided herein are methods of diagnosing a subject for a disease and treating the subject for the disease, wherein the method comprises the use of a non-natural natriuretic peptide comprising one or more D-amino acids.
FILED Thursday, October 04, 2018
APPL NO 16/152336
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/74 (20130101) Original (OR) Class
G01N 2570/00 (20130101)
G01N 2800/32 (20130101)
G01N 2800/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11194014 Jackson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Secretary of the Air Force (SECAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Julie Ann Jackson (Xenia, Ohio);  Forest A. Lee-Elkin (Xenia, Ohio)
ABSTRACT A method and apparatus that measure M coupled channels of radar polarization data ({tilde over (y)}), that is a subset, which is less than the full set of received coupled channels. Sparse recovery operations are performed on the measured M coupled channels of radar polarization data ({tilde over (y)}) and a representation of a set of more than M channels of radar polarization data is generated from the sparse recovery performed on the subset of coupled channels.
FILED Tuesday, February 05, 2019
APPL NO 16/267444
ART UNIT 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/023 (20130101) Original (OR) Class
G01S 7/024 (20130101)
G01S 7/4008 (20130101)
G01S 7/4021 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11194038 Moulder et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
U.S. Air Force
Under Secretary of Defense for Research and Engineering (USDR&E)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) William F. Moulder (Nashua, New Hampshire);  James D. Krieger (Cambridge, Massachusetts);  Denise T. Maurais-Galejs (Carlisle, Massachusetts);  Huy T. Nguyen (Burlington, Massachusetts);  Jeffrey S. Herd (Rowley, Massachusetts)
ABSTRACT A multistatic array topology and image reconstruction process for fast 3D near field microwave imaging are presented. Together, the techniques allow for hardware efficient realization of an electrically large aperture and video-rate image reconstruction. The array topology samples the scene on a regular grid of phase centers, using a tiling of multistatic arrays. Following a multistatic-to-monostatic correction, the sampled data can then be processed with the well-known and highly efficient monostatic Fast Fourier Transform (FFT) imaging algorithm. In this work, the approach is described and validated experimentally with the formation of high quality microwave images. The scheme is more than two orders of magnitude more computationally efficient than the backprojection method. In fact, it is so efficient that a cluster of four commercial off-the-shelf (COTS) graphical processing units (GPUs) can render a 3D image of a human-sized scene in 0.048-0.101 seconds.
FILED Thursday, June 06, 2019
APPL NO 16/433074
ART UNIT 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 13/003 (20130101)
G01S 13/89 (20130101) Original (OR) Class
G01S 13/865 (20130101)
G01S 13/867 (20130101)
G01S 13/887 (20130101)

Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags
G01V 3/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11194082 Zhu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S) Alexander Yutong Zhu (Cambridge, Massachusetts);  Wei-Ting Chen (Cambridge, Massachusetts);  Mohammadreza Khorasaninejad (Cambridge, Massachusetts);  Jaewon Oh (Cambridge, Massachusetts);  Muhammad Aun Abbas Zaidi (Cambridge, Massachusetts);  Robert C. Devlin (Cambridge, Massachusetts);  Federico Capasso (Cambridge, Massachusetts)
ABSTRACT An optical device includes: (1) a substrate; and (2) multiple meta-lenses disposed on the substrate, each meta-lens of the meta-lenses including multiple nanofins disposed on a respective region of the substrate, the nanofins together specifying a phase profile of the meta-lens.
FILED Tuesday, December 19, 2017
APPL NO 16/471549
ART UNIT 2886 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/0208 (20130101)
G01J 3/0224 (20130101)
G01J 3/2823 (20130101)

Optical Elements, Systems, or Apparatus
G02B 3/0043 (20130101)
G02B 5/1861 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11194223 Lipson et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Michal Lipson (New York, New York);  Christopher Thomas Phare (New York, New York);  Moshe Zadka (Bronx, New York)
ABSTRACT A method of forming an emitting array of waveguides, comprising providing a plurality of waveguides that exhibit different propagation constants so as to ensure that nearby waveguides do not couple evenly over parallel propagation lengths by varying a length in one or more dimensions of respective waveguides, whereby the respective waveguides are phase mismatched with at least their nearest neighbor.
FILED Tuesday, June 26, 2018
APPL NO 16/626635
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/125 (20130101)
G02B 6/1228 (20130101)
G02B 6/12011 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/292 (20130101)
G02F 1/2955 (20130101) Original (OR) Class
G02F 1/3544 (20130101)
G02F 2202/30 (20130101)

Antennas, i.e Radio Aerials
H01Q 13/28 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11194550 Davis et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Architecture Technology Corporation (Minneapolis, Minnesota)
ASSIGNEE(S) Architecture Technology Corporation (Minneapolis, Minnesota)
INVENTOR(S) Paul C. Davis (Saratoga, California);  Douglas Sweet (Sunnyvale, California);  Erin Gambucci (San Jose, California)
ABSTRACT A computer-implemented method for migrating a monolithic legacy software system to a well-defined modular target software architecture includes selecting a method, based on predefined patterns, for transforming the software legacy software system; creating an abstract syntax tree from the legacy software system's source code; from the abstract syntax tree, determining a flow of the source code and any coding violations and coding smells in the legacy software system's source code; using the flow and the coding violations, identifying architecture issues in the legacy software system; scheduling tasks for transforming the legacy software system into the target software architecture; automatically generating new source code according to the target software architecture; and automatically and autonomously refactoring the new source code.
FILED Wednesday, August 26, 2020
APPL NO 17/003201
ART UNIT 2192 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 8/30 (20130101) Original (OR) Class
G06F 8/72 (20130101)
G06F 8/76 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11194636 Flajslik et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) Intel Corporation (Santa Clara, California)
ASSIGNEE(S) Intel Corporation (Santa Clara, California)
INVENTOR(S) Mario Flajslik (Hopkinton, Massachusetts);  Keith D. Underwood (Powell, Texas);  Timo Schneider (Hudson, Massachusetts);  James Dinan (Hudson, Massachusetts)
ABSTRACT Technologies for generating triggered conditional events operations include a host fabric interface (HFI) of a compute device configured to receive an operation execution command message associated with a triggered operation that has been fired, process the received operation execution command message to extract and store argument information from the received operation execution command, and increment an event counter associated with the fired triggered operation. The HFI is further configured to perform a triggered compare-and-generate event (TCAGE) operation as a function of the extracted argument information, determine whether to generate a triggering event, generate the triggering event as a function of the performed TCAGE operation, insert the generated triggered event into a triggered operation queue, and update the value of the event counter. Other embodiments are described herein.
FILED Friday, March 30, 2018
APPL NO 15/941509
ART UNIT 2194 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 9/542 (20130101) Original (OR) Class
G06F 9/544 (20130101)
G06F 9/546 (20130101)
G06F 2209/548 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11194744 Dunning et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Qualcomm Intelligent Solutions, Inc. (San Diego, California)
ASSIGNEE(S) Qualcomm Intelligent Solutions, Inc (San Diego, California)
INVENTOR(S) David Stewart Dunning (Portland, Oregon);  Shekhar Yeshwant Borkar (Beaverton, Oregon);  Nitin Yeshwant Borkar (Redmond, Washington);  Matthew Scott Radecic (San Diego, California)
ABSTRACT In-line memory module (IMM) computing nodes with an embedded processor(s) to support local processing of memory-based operations for lower latency and reduced power consumption, and related methods are disclosed. The IMM computing node that includes one or more memory chips mounted on a circuit board. The IMM computing node also includes one or more embedded processor(s) on the circuit board that are each interfaced to at least one memory chip among the one or more memory chips. The processor(s) can be configured to access its interfaced memory chip(s) through an internal memory bus on the circuit board to perform processing onboard the IMM computing node in an offload computing access mode. The embedded processors(s) can also be configured to forward memory access requests received from an external processor to the memory chip(s) for data storage and retrieval in a transparent access mode without further local processing of the memory access requests.
FILED Monday, March 16, 2020
APPL NO 16/820572
ART UNIT 2181 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 13/1668 (20130101) Original (OR) Class
G06F 13/4027 (20130101)
G06F 15/7821 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11194978 Suko et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Scott K. Suko (Dayton, Maryland);  Diana S. Hage (Great Falls, Virginia);  Brian J. Griffiths (Laurel, Maryland);  Parrish E. Ralston (Baltimore, Maryland)
ASSIGNEE(S) Northrop Grumman Systems Corporation (Falls Church, Virginia);  RFID Global Solution, Inc. (Reston, Virginia)
INVENTOR(S) Scott K. Suko (Dayton, Maryland);  Diana S. Hage (Great Falls, Virginia);  Brian J. Griffiths (Laurel, Maryland);  Parrish E. Ralston (Baltimore, Maryland)
ABSTRACT An apparatus and method for combined radio frequency identification (RFID)-based asset management and component authentication are provided. The apparatus comprises a plurality of components to be authenticated, a memory configured to store inventory data, a plurality of root-of-trust (RoT) integrated circuits (ICs), a wired communication bus, and a radio frequency identification (RFID) relay tag. Each RoT IC is mechanically coupled to a corresponding one of the plurality of components and configured to generate authentication data based on a unique key generated for authenticating the corresponding component. The RFID relay tag is connected to each of the RoT ICs via the wired communication bus and is configured to communicate with each of the RoT ICs via the wired communication bus and pass the authentication data and the inventory data to an RFID reader via a radio frequency signal to facilitate authentication of components and inventory management.
FILED Friday, July 12, 2019
APPL NO 16/509869
ART UNIT 2887 — Optics
CURRENT CPC
Electric Digital Data Processing
G06F 2213/0016 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 7/10366 (20130101) Original (OR) Class
G06K 19/0723 (20130101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/087 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/3271 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11195117 Monroe et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) UNIVERSITY OF MARYLAND (College Park, Maryland);  DUKE UNIVERSITY (Durham, North Carolina);  UNIVERSITY OF BRITISH COLUMBIA (Vancouver, Canada)
ASSIGNEE(S) University of Maryland (College Park, Maryland);  Duke University (Durham, North Carolina);  University of British Columbia (Vancouver, Canada)
INVENTOR(S) Christopher Monroe (Ellicott City, Maryland);  Jungsang Kim (Chapel Hill, North Carolina);  Robert Raussendorf (Vancouver, Canada)
ABSTRACT A modular quantum computer architecture is developed with a hierarchy of interactions that can scale to very large numbers of qubits. Local entangling quantum gates between qubit memories within a single modular register are accomplished using natural interactions between the qubits, and entanglement between separate modular registers is completed via a probabilistic photonic interface between qubits in different registers, even over large distances. This architecture is suitable for the implementation of complex quantum circuits utilizing the flexible connectivity provided by a reconfigurable photonic interconnect network. The subject architecture is made fault-tolerant which is a prerequisite for scalability. An optimal quantum control of multimode couplings between qubits is accomplished via individual addressing the qubits with segmented optical pulses to suppress crosstalk in each register, thus enabling high-fidelity gates that can be scaled to larger qubit registers for quantum computation and simulation.
FILED Friday, December 15, 2017
APPL NO 15/844357
ART UNIT 2896 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/113 (20130101)

Electric Digital Data Processing
G06F 15/76 (20130101)
G06F 2015/768 (20130101)

Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11195318 Suma et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Army Research Office (ARO)
APPLICANT(S) UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
ASSIGNEE(S) UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
INVENTOR(S) Evan Suma (Los Angeles, California);  Gerard Medioni (Los Angeles, California);  Mark Bolas (Los Angeles, California);  Ari Y. Shapiro (Sherman Oaks, California);  Wei-Wen Feng (Marina del Rey, California);  Ruizhe Wang (Pasadena, California)
ABSTRACT A non-transitory, tangible, computer-readable storage medium may contain a program of instructions that cause a computer system running the program of instructions to automatically generate a 3D avatar of a living being, including automatically: causing one or more sensors to generate 3D data indicative of the three dimensional shape and appearance of at least a portion of the living being; and generating a virtual character based on the 3D data that can be animated and controlled.
FILED Thursday, April 23, 2015
APPL NO 14/694670
ART UNIT 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Image Data Processing or Generation, in General
G06T 15/005 (20130101) Original (OR) Class
G06T 2215/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11195602 Myers et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Vivonics, Inc. (Bedford, Massachusetts)
ASSIGNEE(S) Vivonics, Inc. (Bedford, Massachusetts)
INVENTOR(S) Ryan Myers (North Andover, Massachusetts);  Gordon B. Hirschman (Cohoes, New York)
ABSTRACT A system to electronically coordinate and document patient care regardless of physical setting. The system includes a wearable subsystem attached to a patient at the point of injury and configured to remain attached to the patient at the point of injury and during one or more encounters with medical personnel or to a time the patient reaches a clinical health care facility. The wearable subsystem is configured to store patient identification information and critical health care information received via wireless communication from an end user computing device at the point of injury and is configured to store added health care information provided by medical personnel from or at the point of injury and during the one or more encounters with the medical personnel or to a time the patient reaches a clinical care facility.
FILED Friday, May 29, 2020
APPL NO 16/887180
ART UNIT 3686 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/6833 (20130101)

Electric Digital Data Processing
G06F 1/163 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 10/65 (20180101) Original (OR) Class

Wireless Communication Networks
H04W 4/80 (20180201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11196072 Gervasio et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
APPLICANT(S) Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
ASSIGNEE(S)
INVENTOR(S) Dominic Francis Gervasio (Tucson, Arizona);  Peiwen Li (Tucson, Arizona);  Xinhai Xu (Tucson, Arizona);  Shuyang Zhang (Tucson, Arizona);  Xiaoxin Wang (Tucson, Arizona)
ABSTRACT A composite proton-conducting membrane comprising an inorganic polymer whose pores are filled with an organic polymer, wherein both the inorganic polymer and the organic polymer are proton conductors and wherein said composite proton-conducting membrane can operate in the absence of solvents, such as water.
FILED Wednesday, June 26, 2019
APPL NO 16/453575
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Positive-displacement Machines for Liquids; Pumps
F04B 43/00 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/92 (20130101)
H01M 4/8605 (20130101)
H01M 8/0258 (20130101)
H01M 8/0267 (20130101)
H01M 8/1213 (20130101) Original (OR) Class
H01M 8/04029 (20130101)
H01M 8/04074 (20130101)
H01M 2008/1095 (20130101)
H01M 2300/002 (20130101)
H01M 2300/0082 (20130101)
H01M 2300/0091 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11196098 McCoy
FUNDED BY
Department of Defense (DOD)
Missile Defense Agency (MDA)
APPLICANT(S) CAMX POWER, LLC. (Lexington, Massachusetts)
ASSIGNEE(S) CAMX Power LLC (Lexington, Massachusetts)
INVENTOR(S) Christopher H. McCoy (Sherborn, Massachusetts)
ABSTRACT A process and system for measuring internal faults in an electrochemical cell. The process for detecting an internal fault in an electrochemical cell includes measuring a voltage difference or a rate of change in voltage difference between a common terminal of a first electrochemical cell and a second electrochemical cell. The measuring is a time measurement. The first electrochemical cell or second electrochemical cell is accepted based on the measuring, or first electrochemical cell or second electrochemical cell is rejected based on the measure of the internal fault of the electrochemical cell.
FILED Friday, November 10, 2017
APPL NO 16/348666
ART UNIT 2868 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/3835 (20190101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/44 (20130101)
H01M 10/482 (20130101)
H01M 10/4285 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11196179 Kindt
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
United States Army (USA)
Department of the Navy (DON)
Naval Research Laboratory (NRL)
Secretary of the Navy (SECNAV)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Rick Kindt (Arlington, Virginia)
ABSTRACT Systems and methods are provided for implementing wideband radiators that conform to regular equilateral triangular lattices with little to no performance compromise for typical offset pairs of dual-polarized element arrangements. This general radiator family/group/configuration can be referred to as the Slant Tri-V (STV) element based on the basic characteristic set of this radiator group and relative differences to conventional array elements normally seen on rectangular or triangular lattice arrangements. The STV array element has wideband, dual-polarized operation and conforms to the most efficiently sampled array lattice for the lowest array element count possible for phased arrays.
FILED Monday, May 18, 2020
APPL NO 16/877216
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 1/40 (20130101)
H01Q 1/243 (20130101)
H01Q 1/245 (20130101)
H01Q 1/2283 (20130101)
H01Q 3/26 (20130101)
H01Q 5/35 (20150115)
H01Q 21/26 (20130101) Original (OR) Class
H01Q 21/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11196182 Taylor et al.
FUNDED BY
Department of Defense (DOD)
Defense MicroElectronics Activity (DMEA)
APPLICANT(S) Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Brian L. Taylor (Anna, Texas);  David M. Dyer (Prosper, Texas);  Steven Sprinkle (Van Alstyne, Texas);  Paul E. Schlittler (Mc Kinney, Texas)
ABSTRACT A radio frequency (RF) circuit connection assembly comprises a RF circuit board and a RF connector. The RF circuit board has a first side and a second side opposite the first side. A RF circuit is located on the first side and an aperture extends through the RF circuit board from the first side to the second side. The RF connector comprises a barrel having a socket configured to receive a RF bullet, a flange having a mounting surface, and a RF connector pin extending laterally from the barrel. The barrel of the RF connector extends through the aperture of the RF circuit board such that the mounting surface of the flange is seated against the first side of the RF circuit board, and the RF connector pin is electrically coupled to the RF circuit on the first side of the RF circuit board.
FILED Tuesday, June 09, 2020
APPL NO 16/897149
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 9/16 (20130101)
H01Q 21/28 (20130101)
H01Q 23/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11196184 Jordan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Cubic Corporation (San Diego, California)
ASSIGNEE(S) Cubic Corporation (San Diego, California)
INVENTOR(S) Jared W Jordan (Raleigh, North Carolina);  Kenneth J Vanhille (Cary, North Carolina);  Timothy A Smith (Durham, North Carolina);  William Stacy (Blacksburg, Virginia);  Benjamin L Cannon (Apex, North Carolina);  David W Sherrer (Cary, North Carolina)
ABSTRACT Antenna arrays, including a broadband single or dual polarized, tightly coupled radiator arrays.
FILED Tuesday, June 19, 2018
APPL NO 16/076354
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 1/40 (20130101)
H01Q 5/25 (20150115)
H01Q 5/48 (20150115)
H01Q 9/065 (20130101)
H01Q 9/285 (20130101)
H01Q 13/085 (20130101)
H01Q 21/24 (20130101)
H01Q 21/062 (20130101)
H01Q 21/064 (20130101)
H01Q 21/0093 (20130101)
H01Q 25/001 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11196430 Tarleton et al.
FUNDED BY
Department of Defense (DOD)
DOD Ordnance Technology Consortium (DOTC)
APPLICANT(S) Honeywell International Inc. (Morris Plains, New Jersey)
ASSIGNEE(S) Honeywell International Inc. (Charlotte, North Carolina)
INVENTOR(S) Norman Gerard Tarleton (Glendale, Arizona);  Chuck Croker (Glendale, Arizona);  Lee K. Strandjord (Tonka Bay, Minnesota)
ABSTRACT In one embodiment, a phase lock loop circuit includes a control circuit, wherein the control circuit is configured to input an estimation having a second frequency and a second phase. The second frequency is selected from a range of frequencies including a first frequency from an acquired signal. A numerically controlled oscillator is coupled to the control circuit, wherein the control circuit is configured to control an output response of the numerically controlled oscillator. The numerically controlled oscillator is configured to receive the estimation from the control circuit and generate an output signal in response to the estimation. A phase detector is coupled to the control circuit and the numerically controlled oscillator, wherein the phase detector is configured to compare the first signal and the output signal and produce a comparison output, the comparison output indicative of a phase difference between the first signal and the estimation.
FILED Wednesday, February 19, 2020
APPL NO 16/795365
ART UNIT 2896 — Electrical Circuits and Systems
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 19/727 (20130101)

Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses
H03L 7/093 (20130101)
H03L 7/103 (20130101) Original (OR) Class
H03L 7/0994 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11196486 Hosseini et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Research Laboratory (ARL)
Army Research Office (ARO)
Department of the Navy (DON)
U.S. Navy
APPLICANT(S) Analog Photonics LLC (Boston, Massachusetts)
ASSIGNEE(S) Analog Photonics LLC (Boston, Massachusetts)
INVENTOR(S) Ehsan Shah Hosseini (Boston, Massachusetts);  Michael Robert Watts (Hingham, Massachusetts)
ABSTRACT Optical communication with a remote node comprises: transmitting at least one optical beam to the remote node; receiving at least a portion of at least one optical beam from the remote node; providing intensity information based on one or more signals from one or more optical detector modules in an array of optical detector modules detecting the portion of the optical beam received from the remote node; and controlling at least one optical phased array to steer the optical beam transmitted to the remote node based on intensity information received from the remote node.
FILED Monday, November 09, 2020
APPL NO 17/092531
ART UNIT 2636 — Optical Communications
CURRENT CPC
Transmission
H04B 10/112 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11196782 Ethier et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of the Navy (DON)
Space and Naval Warfare Systems (SPAWAR)
APPLICANT(S) The MITRE Corporation (McLean, Virginia)
ASSIGNEE(S) The MITRE Corporation (McLean, Virginia)
INVENTOR(S) Randall Paul Joseph Ethier (Burke, Virginia);  Gene Lee Harrison (Leesburg, Virginia)
ABSTRACT Disclosed herein are system, apparatus, method and/or computer program product embodiments for providing survivable calling and conferencing. An embodiment operates by providing, by a first server, a first sub-conference to a plurality of user devices over first lines. The first sub-conference is combined with a second sub-conference to form a collective conference of the plurality of user devices. The first server accesses the conference. A second server is configured to provide the second sub-conference of the collective conference to the plurality of user devices over second lines, the first and second lines being distinct from each other. The collective conference may provide resilient and reliable sharing of information among participants and may leverage dispersed elements or diverse links simultaneously without impediments of echoes, loops, or other impacts.
FILED Friday, December 11, 2020
APPL NO 17/119187
ART UNIT 2454 — Computer Networks
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 65/80 (20130101)
H04L 65/403 (20130101) Original (OR) Class
H04L 65/1073 (20130101)
H04L 65/1096 (20130101)
H04L 65/4076 (20130101)
H04L 67/10 (20130101)
H04L 69/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 11192760 Nadiadi et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
National Technology and Engineering Solutions of Sandia, LLC (NTESS)
Sandia National Laboratories (SNL)
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Irfan Nadiadi (Richmond, California);  John Monson (Livermore, California)
ABSTRACT An assembly for rotating a workpiece including a locking side pull hoist ring removably attachable to a side surface of the workpiece. The locking side pull hoist ring comprises a load bearing structure, a rotation mechanism attached to the side surface of the workpiece that rotates about a rotation axis extending through the rotation mechanism, a locking mechanism configured to transition between a locked state and an unlocked state, and a support member connecting the load bearing structure and the rotation mechanism. The support member rotatably supports the rotation mechanism for rotation about the rotation axis and rotatably supports the load bearing structure for rotation about a second axis. In the locked state, the locking mechanism prevents rotation of the rotation mechanism by securing the rotation mechanism to the support member.
FILED Wednesday, July 15, 2020
APPL NO 16/929852
ART UNIT 3651 — Material and Article Handling
CURRENT CPC
Cranes; Load-engaging Elements or Devices for Cranes, Capstans, Winches, or Tackles
B66C 1/66 (20130101) Original (OR) Class

Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing
F16B 45/00 (20130101)
F16B 2200/506 (20180801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11192783 Stavila et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
National Technology and Engineering Solutions of Sandia, LLC (NTESS)
Sandia National Laboratories (SNL)
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Vitalie Stavila (Pleasanton, California);  Leonard E. Klebanoff (Dublin, California)
ABSTRACT A method and a system is provided for obtaining solid-state hydrogen storage and release in materials with at least theoretical loaded hydrogen densities of 11 wt % or greater that can deliver hydrogen and be recharged at moderate temperatures enabling incorporation into hydrogen storage systems suitable for transportation applications. These materials comprise ternary boride materials comprising certain light transition metals and alkaline or alkaline earth metals, and ideally have no or very little phase separation. A process of making these materials is also provided.
FILED Tuesday, November 14, 2017
APPL NO 15/812254
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 3/0031 (20130101) Original (OR) Class
C01B 3/0078 (20130101)
C01B 3/0084 (20130101)
C01B 6/21 (20130101)
C01B 6/23 (20130101)
C01B 6/24 (20130101)
C01B 35/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193075 Monroe et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
National Technology and Engineering Solutions of Sandia, LLC (NTESS)
Sandia National Laboratories (SNL)
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Eric Monroe (Pleasanton, California);  Joseph Carlson (Castro Valley, California);  Ryan Wesley Davis (San Jose, California)
ABSTRACT A fuel for an internal combustion engine includes a fatty alkyl ether having a formula corresponding to formula (II):
wherein x is 1-8, and y is 0 to 3; and the alkyl is an alkyl group having a number of carbon atoms that is less than the number of carbon atoms in the alkyl chain on the opposite side of the oxygen atom. The fatty alky ether can be used as a neat fuel or blend with biodiesel, diesel, ethanol or other fuels. The fatty alkyl ethers are improved in cetane number and cold flow properties over a biodiesel with fatty acid methyl acid methyl ester compounds. This is particularly valuable for compression ignition engines. A method of combustion in several types of engines is also disclosed.
FILED Thursday, July 16, 2020
APPL NO 16/930453
ART UNIT 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters
C10L 1/02 (20130101)
C10L 1/1852 (20130101) Original (OR) Class
C10L 10/12 (20130101)
C10L 10/16 (20130101)
C10L 2200/0484 (20130101)

Internal-combustion Piston Engines; Combustion Engines in General
F02B 1/02 (20130101)
F02B 1/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193078 Ohler et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Amyris, Inc. (Emeryville, California)
ASSIGNEE(S) AMYRIS, INC. (Emeryville, California)
INVENTOR(S) Nicholas Ohler (Emeryville, California);  Karl Fisher (Emeryville, California);  Jin Ki Hong (Emeryville, California)
ABSTRACT Provided herein are olefinic feedstocks derived from conjugated hydrocarbon terpenes (e.g., C10-C30 terpenes), methods for making the same, and methods for their use.
FILED Friday, April 19, 2019
APPL NO 16/389690
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 5/03 (20130101)
C07C 5/05 (20130101)
C07C 5/05 (20130101)
C07C 11/02 (20130101)
C07C 2521/04 (20130101)
C07C 2523/44 (20130101)
C07C 2523/75 (20130101)

Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters
C10L 1/04 (20130101)

Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition
C10M 105/02 (20130101) Original (OR) Class
C10M 105/04 (20130101)
C10M 107/14 (20130101)
C10M 2203/003 (20130101)
C10M 2203/022 (20130101)
C10M 2203/024 (20130101)
C10M 2203/0206 (20130101)
C10M 2205/083 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 20/582 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193133 Bartley et al.
FUNDED BY
Department of Energy (DOE)
Lawrence Berkeley National Laboratory (LBNL)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Laura E. Bartley (Norman, Oklahoma);  Pamela Ronald (Davis, California);  Henrik Vibe Scheller (Millbrae, California)
ABSTRACT The invention provides methods of engineering plants to modulate hydroxycinnamic acid content. The invention additionally provides compositions and methods comprising such plants.
FILED Monday, October 21, 2019
APPL NO 16/659230
ART UNIT 1663 — Plants
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1025 (20130101)
C12N 15/8246 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193190 Maziasz et al.
FUNDED BY
Department of Energy (DOE)
UT-Battelle, LLC (UT-BATTELLE)
APPLICANT(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Philip J Maziasz (Oak Ridge, Tennessee);  Govindarajan Muralidharan (Knoxville, Tennessee);  Bruce A. Pint (Knoxville, Tennessee);  Kinga A. Unocic (Knoxville, Tennessee);  Ying Yang (Farragut, Tennessee)
ABSTRACT An air castable Fe-based stainless steel alloy comprises in weight % based on the total weight of the alloy 18-22% Cr, 15-22% Ni, 3-6% Al, 0.5-5% Mn, 0-3.5% W, 0-5% Cu, 0-2% Si, 1-2.5% Nb, 0.3-0.6% C balance Fe wherein, Cu+W+Si=0.5-10.5, and the alloy provides an oxidation resistance of 0.5<specific mass change<+2 mg/cm2 after 400 one hour cycles at 900° C. in 10% water vapor.
FILED Friday, July 12, 2019
APPL NO 16/510524
ART UNIT 1737 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Alloys
C22C 38/06 (20130101)
C22C 38/34 (20130101)
C22C 38/38 (20130101)
C22C 38/42 (20130101) Original (OR) Class
C22C 38/44 (20130101)
C22C 38/48 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193688 Konrad et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Trustees of Boston University (Boston, Massachusetts)
ASSIGNEE(S) Trustees of Boston University (Boston, Massachusetts)
INVENTOR(S) Janusz L. Konrad (Framingham, Massachusetts);  Prakash Ishwar (Brookline, Massachusetts);  Thomas D C Little (Newton, Massachusetts);  Michael Gevelber (Auburndale, Massachusetts)
ABSTRACT Sensing and control apparatus for a building HVAC system includes interior and boundary sensors, such as cameras and thermal sensors, generating sensor signals conveying occupancy-related features for an area. A controller uses the sensor signals to produce an occupancy estimate and to generate equipment-control signals to cause the HVAC system to supply conditioned air to the area based on the occupancy estimate. The controller includes fusion systems collectively generating the occupancy estimate by corresponding fusion calculations, the fusion systems producing a boundary occupancy-count change based on sensor signals from the boundary sensors, an interior occupancy count based on sensor signals from the interior sensors, and the overall occupancy estimate. Fusion may be of one or multiple types including cross-modality fusion across different sensor types, within-modality fusion across different instances of same-type sensors, and cross-algorithm fusion using different algorithms for the same sensor(s).
FILED Thursday, May 23, 2019
APPL NO 16/420797
ART UNIT 2896 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening
F24F 11/47 (20180101)
F24F 11/56 (20180101) Original (OR) Class
F24F 11/63 (20180101)
F24F 11/74 (20180101)
F24F 11/88 (20180101)
F24F 11/89 (20180101)
F24F 2120/10 (20180101)
F24F 2120/12 (20180101)
F24F 2120/14 (20180101)

Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 2219/2614 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193696 Holladay et al.
FUNDED BY
Department of Energy (DOE)
Battelle Memorial Institute (BATTELLE)
Pacific Northwest National Laboratory (PNNL)
APPLICANT(S) Jamie D. Holladay (Richland, Washington);  Kerry D. Meinhardt (Kennewick, Washington);  Evgueni Polikarpov (Richland, Washington);  Edwin C. Thomsen (Richland, Washington);  John Barclay (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington);  Emerald Energy NW, LLC (Bothell, Washington)
INVENTOR(S) Jamie D. Holladay (Richland, Washington);  Kerry D. Meinhardt (Kennewick, Washington);  Evgueni Polikarpov (Richland, Washington);  Edwin C. Thomsen (Richland, Washington);  John Barclay (Richland, Washington)
ABSTRACT A process for liquefying a process gas that includes introducing a heat transfer fluid into an active magnetic regenerative refrigerator apparatus that comprises a single stage comprising dual multilayer regenerators located axially opposite to each other.
FILED Tuesday, March 27, 2018
APPL NO 15/937776
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems
F25B 21/00 (20130101) Original (OR) Class
F25B 2321/0021 (20130101)
F25B 2321/0022 (20130101)

Refrigerators; Cold Rooms; Ice-boxes; Cooling or Freezing Apparatus Not Otherwise Provided for
F25D 11/02 (20130101)

Liquefaction, Solidification or Separation of Gases or Gaseous Mixtures by Pressure and Cold Treatment
F25J 1/001 (20130101)
F25J 2270/908 (20130101)

Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 15/0275 (20130101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 1/012 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 37/04 (20130101)

Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications
Y02B 30/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193825 Rimshaw et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOEOS)
APPLICANT(S) The Penn State Research Foundation (University Park, Pennsylvania)
ASSIGNEE(S) The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S) Adam Rimshaw (Fairfield, Pennsylvania);  Christopher Grieco (Yonkers, New York);  Eric Kennehan (Berlin Center, Ohio);  John B. Asbury (State College, Pennsylvania)
ABSTRACT A high-sensitivity nanosecond to millisecond transient absorption spectrometer for measurements of miniscule signals under low excitation intensities includes an excitation source generating a >100 Hz, <5 ns pulsewidth excitation pulse for exciting a light absorbing sample, a probe light source for generating a high photon flux probe light beam producing an average irradiance greater than 1 μW m-2 nm-1 for measuring the transient absorption spectrum of the sample before and after excitation by the excitation source, a DC-coupled detector capable of measuring light for enabling synchronous measurement of both the transmission of the probe light beam and the change in transmission of the probe light beam between a signal with the excitation pulse present and a signal in the absence of the excitation pulse, and a digital oscilloscope with a trigger rearm time capable of collecting every trigger event at frequencies including 1MHz, for enabling sequential noise subtraction protocols.
FILED Thursday, May 24, 2018
APPL NO 16/613717
ART UNIT 2886 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/18 (20130101)
G01J 3/42 (20130101) Original (OR) Class
G01J 3/0297 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/31 (20130101)
G01N 2021/3125 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 13/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193884 Frenkel et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOEOS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Research Foundation for The State University of New York (Albany, New York)
ASSIGNEE(S) The Research Foundation for The State University of New York (Albany, New York)
INVENTOR(S) Anatoly Frenkel (Great Neck, New York);  Janis Timosenko (Upton, New York)
ABSTRACT A method of supervised machine learning-based spectrum analysis information, using a neural network trained with spectrum information, to identify a specified feature of a given material, a system for supervised machine learning-based spectrum analysis, and a method of training a neural network to analyze spectrum data. The method of supervised machine learning-base spectrum analysis comprises inputting into the neural network spectrum data obtained from a sample of the given material; and the neural network processing the spectrum data, in accordance with the training of the neural network, and outputting one or more values for the specified feature of the sample of the material. In an embodiment, the training set of data includes x-ray absorption spectroscopy data for the given material. In an embodiment, the training set of data includes electron energy loss spectra (EELS) data.
FILED Tuesday, July 02, 2019
APPL NO 16/460117
ART UNIT 2884 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/3103 (20130101) Original (OR) Class

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 20/00 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193979 Steingart et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Feasible, Inc. (Emeryville, California);  The Trustees of Princeton University (Princeton, New Jersey)
ASSIGNEE(S) Feasible, Inc. (Emeryville, California);  The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S) Daniel A. Steingart (Princeton, New Jersey);  Greg Davies (Plainsboro, New Jersey);  Shaurjo Biswas (El Cerrito, California);  Andrew G. Hsieh (Berkeley, California);  Barry Van Tassell (El Cerrito, California);  Thomas Hodson (Princeton, New Jersey);  Shan Dou (Berkeley, California)
ABSTRACT Systems and methods for prediction of state of charge (SOH), state of health (SOC) and other characteristics of batteries using acoustic signals, includes determining acoustic data at two or more states of charge and determining a reduced acoustic data set representative of the acoustic data at the two or more states of charge. The reduced acoustic data set includes time of flight (TOF) shift, total signal amplitude, or other data points related to the states of charge. Machine learning models use at least the reduced acoustic dataset in conjunction with non-acoustic data such as voltage and temperature for predicting the characteristics of any other independent battery.
FILED Thursday, August 30, 2018
APPL NO 16/117421
ART UNIT 2862 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 29/07 (20130101)
G01N 29/11 (20130101)
G01N 29/12 (20130101)
G01N 29/043 (20130101)
G01N 29/46 (20130101)
G01N 29/48 (20130101)
G01N 29/50 (20130101)
G01N 29/4418 (20130101)
G01N 29/4436 (20130101)
G01N 29/4481 (20130101)
G01N 2291/011 (20130101)
G01N 2291/102 (20130101)
G01N 2291/02441 (20130101)
G01N 2291/2697 (20130101)
G01N 2291/02827 (20130101)
G01N 2291/02854 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/385 (20190101) Original (OR) Class
G01R 31/392 (20190101)
G01R 31/3835 (20190101)
G01R 31/3842 (20190101)

Computer Systems Based on Specific Computational Models
G06N 5/046 (20130101)
G06N 20/00 (20190101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/48 (20130101)
H01M 10/425 (20130101)
H01M 10/486 (20130101)
H01M 10/4285 (20130101)
H01M 2010/4271 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11194059 Frisch et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOEOS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Physics (PHY)
APPLICANT(S) The University of Chicago (Chicago, Illinois)
ASSIGNEE(S) The University of Chicago (Chicago, Illinois)
INVENTOR(S) Henry J. Frisch (Chicago, Illinois);  Evan Angelico (San Marcos, California);  Andrey Elagin (Bolingbrook, Illinois);  Eric Spieglan (Lisle, Illinois)
ABSTRACT Hermetically sealed electronic devices and methods for fabricating the hermetically sealed electronic devices are provided. The devices include a solder sealed vacuum housing. The solder seal is formed using a solder wick having an external solder reservoir. When the reservoir is filled with molten solder, the solder is drawn via capillary action into a precisely defined narrow gap between two components of the housing where it forms an airtight and vacuum-tight seal.
FILED Tuesday, April 07, 2020
APPL NO 16/842261
ART UNIT 2847 — Electrical Circuits and Systems
CURRENT CPC
Measurement of Nuclear or X-radiation
G01T 1/17 (20130101) Original (OR) Class

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/0203 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 5/03 (20130101)
H05K 5/062 (20130101)
H05K 5/063 (20130101)
H05K 5/069 (20130101)
H05K 5/0247 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11194373 Al-Rawi et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Intel Corporation (Santa Clara, California)
ASSIGNEE(S) Intel Corporation (Santa Clara, California)
INVENTOR(S) Asma Al-Rawi (Hillsboro, Oregon);  Federico Ardanaz (Hillsboro, Oregon);  Jonathan M. Eastep (Portland, Oregon);  Nikhil Gupta (Portland, Oregon);  Ankush Varma (Hillsboro, Oregon);  Krishnakanth V. Sistla (Beaverton, Oregon);  Ian M. Steiner (Portland, Oregon)
ABSTRACT Various embodiments comprise prioritizing frequency allocations in thermally- or power-constrained computing devices. Computer elements may be assigned ‘weights’ based on their priorities. The computer elements with higher weights may receive higher frequency allocations to assure they receive priority in processing more quickly. The computer elements with lower weights may receive lower frequency allocations and suffer a slowdown in their processing. Elements with the same weight may be grouped together for the purpose of frequency allocation.
FILED Monday, April 20, 2020
APPL NO 16/853570
ART UNIT 2186 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 1/206 (20130101)
G06F 1/324 (20130101)
G06F 1/3206 (20130101) Original (OR) Class
G06F 1/3228 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 12/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11194634 Rao et al.
FUNDED BY
Department of Energy (DOE)
Exascale Computing Project (ECP)
PathForward Project (PATHFORWARD)
Lawrence Livermore National Laboratory (LLNL)
APPLICANT(S) Advanced Micro Devices, Inc. (Santa Clara, California)
ASSIGNEE(S) Advanced Micro Devices, Inc. (Santa Clara, California)
INVENTOR(S) Karthik Rao (Austin, Texas);  Shomit N. Das (Austin, Texas);  Xudong An (Austin, Texas);  Wei Huang (Dallas, Texas)
ABSTRACT In some examples, thermal aware optimization logic determines a characteristic (e.g., a workload or type) of a wavefront (e.g., multiple threads). For example, the characteristic indicates whether the wavefront is compute intensive, memory intensive, mixed, and/or another type of wavefront. The thermal aware optimization logic determines temperature information for one or more compute units (CUs) in one or more processing cores. The temperature information includes predictive thermal information indicating expected temperatures corresponding to the one or more CUs and historical thermal information indicating current or past thermal temperatures of at least a portion of a graphics processing unit (GPU). The logic selects the one or more compute units to process the plurality of threads based on the determined characteristic and the temperature information. The logic provides instructions to the selected subset of the plurality of CUs to execute the wavefront.
FILED Friday, December 14, 2018
APPL NO 16/220827
ART UNIT 2193 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 1/3206 (20130101)
G06F 3/0613 (20130101)
G06F 9/3867 (20130101)
G06F 9/3877 (20130101)
G06F 9/4893 (20130101)
G06F 9/5027 (20130101)
G06F 9/5094 (20130101) Original (OR) Class
G06F 13/409 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/12 (20130101)

Pictorial Communication, e.g Television
H04N 19/436 (20141101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11194707 Stalzer
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Mark A. Stalzer (Pasadena, California)
ABSTRACT Systems and methods of building massively parallel computing systems using low power computing complexes in accordance with embodiments of the invention are disclosed. A massively parallel computing system in accordance with one embodiment of the invention includes at least one Solid State Blade configured to communicate via a high performance network fabric. In addition, each Solid State Blade includes a processor configured to communicate with a plurality of low power computing complexes interconnected by a router, and each low power computing complex includes at least one general processing core, an accelerator, an I/O interface, and cache memory and is configured to communicate with non-volatile solid state memory.
FILED Friday, January 18, 2019
APPL NO 16/252332
ART UNIT 2136 — Memory Access and Control
CURRENT CPC
Electric Digital Data Processing
G06F 12/0246 (20130101) Original (OR) Class
G06F 12/0866 (20130101)
G06F 2212/214 (20130101)
G06F 2212/224 (20130101)
G06F 2212/7201 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 49/25 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11194763 Grider
FUNDED BY
Department of Energy (DOE)
Los Alamos National Laboratory (LANL)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Triad National Security, LLC (Triad)
APPLICANT(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S) Triad National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Gary A. Grider (Los Alamos, New Mexico)
ABSTRACT Systems, apparatus, and methods are disclosed for performing scalable operations in a file system. Metadata entries in a namespace or directory tree are sharded across multiple file metadata servers. An augmented enumeration operation, such as listing a directory, is parallelized across the multiple file metadata servers, transparently to clients. Exemplary augmentation features can include filtering and sorting. Augmentation features can be executed concurrently with enumeration, prior to enumeration, after enumeration, or as a combination of these, and can utilize pre-built index structures or holding structures for intermediate results. Augmented enumeration operations can also include no-output operations such as changing file attributes or deleting a file, and cumulative operations such as counting total disk space usage. The parallelization is compatible with tree-level parallelization and storage-level parallelization. Disclosed technologies can be applied to other fields requiring scalable enumeration, such as database and network applications.
FILED Friday, September 22, 2017
APPL NO 15/713495
ART UNIT 2168 — Data Bases & File Management
CURRENT CPC
Electric Digital Data Processing
G06F 16/14 (20190101) Original (OR) Class
G06F 16/134 (20190101)
G06F 16/162 (20190101)
G06F 16/1767 (20190101)
G06F 16/2246 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11195504 Hammetter et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
National Technology and Engineering Solutions of Sandia, LLC (NTESS)
Sandia National Laboratories (SNL)
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Chris Hammetter (Albuquerque, New Mexico);  Michael B. Sinclair (Albuquerque, New Mexico);  Timothy F. Walsh (West Lafayette, Indiana);  Harlan James Brown-Shaklee (Albuquerque, New Mexico)
ABSTRACT A method and apparatus for attenuating acoustic waves is provided. A lattice is formed with a plurality of support struts. A plurality of resonating struts are formed extending between the support struts, wherein the resonating struts are configured to attenuate acoustic waves within a predetermined range of frequencies while allowing acoustic waves outside the predetermined range of frequencies to pass through the resonant structure unattenuated. The resonant structure is interposed between two bodies to isolate one body from acoustic waves from the other body over the predetermined range of frequencies.
FILED Friday, November 30, 2018
APPL NO 16/206722
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 50/02 (20141201)
B33Y 80/00 (20141201)

Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for
G10K 11/162 (20130101) Original (OR) Class
G10K 11/172 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11195644 Wang et al.
FUNDED BY
Department of Energy (DOE)
UT-Battelle, LLC (UT-BATTELLE)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota);  UT-BATTELLE, LLC (Oak Ridge, Tennessee);  UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee)
ASSIGNEE(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota);  UT-BATTELLE, LLC (Oak Ridge, Tennessee);  UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee)
INVENTOR(S) Jian-Ping Wang (Shoreview, Minnesota);  Yanfeng Jiang (Minneapolis, Minnesota);  Craig A. Bridges (Knoxville, Tennessee);  Michael Brady (Oak Ridge, Tennessee);  Orlando Rios (Knoxville, Tennessee);  Roberta A. Meisner (Knoxville, Tennessee);  Lawrence F. Allard (Knoxville, Tennessee);  Edgar Lara-Curzio (Lenoir City, Tennessee);  Shihai He (Fremont, California)
ABSTRACT The disclosure describes techniques for forming nanoparticles including Fe16N2 phase. In some examples, the nanoparticles may be formed by first forming nanoparticles including iron, nitrogen, and at least one of carbon or boron. The carbon or boron may be incorporated into the nanoparticles such that the iron, nitrogen, and at least one of carbon or boron are mixed. Alternatively, the at least one of carbon or boron may be coated on a surface of a nanoparticle including iron and nitrogen. The nano particle including iron, nitrogen, and at least one of carbon or boron then may be annealed to form at least one phase domain including at least one of Fe16N2, Fe16(NB)2, Fe16(NC)2, or Fe16(NCB)2.
FILED Thursday, March 26, 2015
APPL NO 15/129439
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/0018 (20130101)

Alloys
C22C 38/001 (20130101)
C22C 38/002 (20130101)
C22C 2202/02 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 14/0036 (20130101)
C23C 14/165 (20130101)
C23C 14/185 (20130101)
C23C 14/566 (20130101)
C23C 14/568 (20130101)
C23C 14/586 (20130101)
C23C 14/0605 (20130101)
C23C 14/3414 (20130101)
C23C 14/3464 (20130101)
C23C 14/5806 (20130101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 1/047 (20130101) Original (OR) Class
H01F 1/0054 (20130101)
H01F 1/065 (20130101)
H01F 41/0253 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11195667 Liang et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOEOS)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S) Yu Teng Liang (Chicago, Illinois);  Baiju K. Vijayan (Kerala, India);  Kimberly A. Gray (Evanston, Illinois);  Mark C. Hersam (Wilmette, Illinois)
ABSTRACT In one aspect of the invention, a dye sensitized solar cell has a counter-electrode including carbon-titania nanocomposite thin films made by forming a carbon-based ink; forming a titania (TiO2) solution; blade-coating a mechanical mixture of the carbon-based ink and the titania solution onto a substrate; and annealing the blade-coated substrate at a first temperature for a first period of time to obtain the carbon-based titania nanocomposite thin films. In certain embodiments, the carbon-based titania nanocomposite thin films may include solvent-exfoliated graphene titania (SEG-TiO2) nanocomposite thin films, or single walled carbon nanotube titania (SWCNT-TiO2) nanocomposite thin films.
FILED Tuesday, June 14, 2016
APPL NO 15/181802
ART UNIT 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 21/18 (20130101)
B01J 35/004 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/19 (20170801)
C01B 32/192 (20170801)

Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 23/053 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2004/03 (20130101)
C01P 2004/04 (20130101)
C01P 2004/24 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 11/52 (20130101)

Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 9/2022 (20130101) Original (OR) Class

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/00 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/542 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 70/50 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11195968 Jiang et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Texas Tech University System (Lubbock, Texas)
ASSIGNEE(S) Texas Tech University System (Lubbock, Texas)
INVENTOR(S) Hongxing Jiang (Lubbock, Texas);  Jingyu Lin (Lubbock, Texas);  Jing Li (Lubbock, Texas);  Avisek Maity (Lubbock, Texas);  Sam Grenadier (Lubbock, Texas)
ABSTRACT A method for fabricating a neutron detector includes providing an epilayer wafer of Boron-10 enriched hexagonal boron nitride (h-10BN or h-BN or 10BN or BN) having a thickness (t), dicing or cutting the epilayer wafer into one or more BN strips having a width (W) and a length (L), and depositing a first metal contact on a first surface of at least one of the BN strip and a second metal contact on a second surface of the at least one BN strip. The neutron detector includes an electrically insulating submount, a BN epilayer of Boron-10 enriched hexagonal boron nitride (h-10BN or h-BN or 10BN or BN) placed on the insulating submount, a first metal contact deposited on a first surface of the BN epilayer, and a second metal contact deposited on a second surface of the BN epilayer.
FILED Wednesday, June 10, 2020
APPL NO 16/897742
ART UNIT 2897 — Semiconductors/Memory
CURRENT CPC
Measurement of Nuclear or X-radiation
G01T 3/08 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/036 (20130101)
H01L 31/115 (20130101) Original (OR) Class
H01L 31/1856 (20130101)
H01L 31/1892 (20130101)
H01L 31/02019 (20130101)
H01L 31/03044 (20130101)
H01L 31/022408 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11196053 Pan et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Ke-Ji Pan (Ellicott City, Maryland);  Mohammed Hussain Abdul Jabbar (College Park, Maryland);  Dong Ding (Idaho Falls, Idaho);  Eric Wachsman (Fulton, Maryland)
ASSIGNEE(S) REDOX POWER SYSTEMS, LLC (College Park, Maryland);  UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland)
INVENTOR(S) Ke-Ji Pan (Ellicott City, Maryland);  Mohammed Hussain Abdul Jabbar (College Park, Maryland);  Dong Ding (Idaho Falls, Idaho);  Eric Wachsman (Fulton, Maryland)
ABSTRACT In various embodiments, a solid oxide fuel cell features a functional layer for reducing interfacial resistance between the cathode and the solid electrolyte.
FILED Tuesday, September 17, 2019
APPL NO 16/572938
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes for Applying Fluent Materials to Surfaces, in General
B05D 3/0254 (20130101)
B05D 7/50 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/8663 (20130101) Original (OR) Class
H01M 4/9033 (20130101)
H01M 4/9066 (20130101)
H01M 8/126 (20130101)
H01M 8/1213 (20130101)
H01M 8/1246 (20130101)
H01M 8/1253 (20130101)
H01M 2008/1293 (20130101)
H01M 2250/30 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/50 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 70/50 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11196057 Friesen et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (Tempe, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (Tempe, Arizona)
INVENTOR(S) Cody A. Friesen (Fort McDowell, Arizona);  Daniel Buttry (Tempe, Arizona)
ABSTRACT Systems and methods drawn to an electrochemical cell comprising a low temperature ionic liquid comprising positive ions and negative ions and a performance enhancing additive added to the low temperature ionic liquid. The additive dissolves in the ionic liquid to form cations, which are coordinated with one or more negative ions forming ion complexes. The electrochemical cell also includes an air electrode configured to absorb and reduce oxygen. The ion complexes improve oxygen reduction thermodynamics and/or kinetics relative to the ionic liquid without the additive.
FILED Thursday, June 27, 2019
APPL NO 16/455185
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/86 (20130101)
H01M 4/90 (20130101)
H01M 8/02 (20130101) Original (OR) Class
H01M 8/08 (20130101)
H01M 12/06 (20130101)
H01M 12/08 (20130101)
H01M 2300/0022 (20130101)
H01M 2300/0025 (20130101)
H01M 2300/0045 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11196072 Gervasio et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
APPLICANT(S) Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
ASSIGNEE(S)
INVENTOR(S) Dominic Francis Gervasio (Tucson, Arizona);  Peiwen Li (Tucson, Arizona);  Xinhai Xu (Tucson, Arizona);  Shuyang Zhang (Tucson, Arizona);  Xiaoxin Wang (Tucson, Arizona)
ABSTRACT A composite proton-conducting membrane comprising an inorganic polymer whose pores are filled with an organic polymer, wherein both the inorganic polymer and the organic polymer are proton conductors and wherein said composite proton-conducting membrane can operate in the absence of solvents, such as water.
FILED Wednesday, June 26, 2019
APPL NO 16/453575
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Positive-displacement Machines for Liquids; Pumps
F04B 43/00 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/92 (20130101)
H01M 4/8605 (20130101)
H01M 8/0258 (20130101)
H01M 8/0267 (20130101)
H01M 8/1213 (20130101) Original (OR) Class
H01M 8/04029 (20130101)
H01M 8/04074 (20130101)
H01M 2008/1095 (20130101)
H01M 2300/002 (20130101)
H01M 2300/0082 (20130101)
H01M 2300/0091 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11196338 Beddingfield et al.
FUNDED BY
Department of Energy (DOE)
National Energy Technology Laboratory (NETL)
SunShot National Laboratory Multiyear Partnership (SuNLaMP)
APPLICANT(S) North Carolina State University (Raleigh, North Carolina)
ASSIGNEE(S) North Carolina State University (Raleigh, North Carolina)
INVENTOR(S) Richard B. Beddingfield (Raleigh, North Carolina);  Subhashish Bhattacharya (Raleigh, North Carolina)
ABSTRACT Various examples are provided related to semiconductor topologies and devices that can be used for soft starting and active fault protection of power converters. In one example, an active switch device includes an active switch having a gating control input; and a thyristor having a gating control input. The thyristor is coupled in parallel with the active switch. The active switch can be an IGBT, MOSFET, or other appropriate device. In another example, a power converter can include the active switch devices and switching control circuitry coupled to gating control inputs of the active switch devices.
FILED Saturday, December 29, 2018
APPL NO 16/958959
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 1/32 (20130101)
H02M 1/36 (20130101) Original (OR) Class
H02M 7/1557 (20130101)

Pulse Technique
H03K 17/164 (20130101)
H03K 17/08124 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11196611 Patel et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
National Technology and Engineering Solutions of Sandia, LLC (NTESS)
Sandia National Laboratories (SNL)
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Silpan M. Patel (Albuquerque, New Mexico);  Peter A. Knee (Albuquerque, New Mexico)
ABSTRACT Various technologies for communicating with systems that communicate using an unknown communications protocol are described herein. A transceiver intercepts a plurality of communications exchanged between two or more transceivers on a communications network. Pattern-recognition algorithms are executed over the plurality of communications, and features of an unknown communications protocol that governs the communications between the two or more transceivers are inferred based upon output of the pattern-recognition algorithms. A communication is formatted based upon the inferred features of the unknown communications protocol, and the communication transmitted to one or more systems on the communications network by way of the transceiver. The communication at least partially conforms to the unknown communications protocol, and so may be interpreted by systems on the network.
FILED Thursday, August 24, 2017
APPL NO 15/685373
ART UNIT 2457 — Computer Networks
CURRENT CPC
Electric Digital Data Processing
G06F 17/18 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00523 (20130101)
G06K 9/6201 (20130101)

Computer Systems Based on Specific Computational Models
G06N 5/04 (20130101)
G06N 20/00 (20190101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 29/06013 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11197401 Hatch et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Kansas City National Security Campus (KCNSC)
Honeywell Federal Manufacturing and Technologies, LLC (FM&T)
APPLICANT(S) HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri)
ASSIGNEE(S) Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
INVENTOR(S) Jonathan Douglas Hatch (Cleveland, Missouri);  Stephen McGarry Hatch (Blue Springs, Missouri)
ABSTRACT A method for the large-scale production of PCBs including a continuous selective adhesion process for creating printed circuit traces providing input to a production line. A roll of printed circuit traces is produced using rolls of flexible substrate, conductive layer, and conductive layer support by applying adhesive between the rolls of flexible substrate and conductive layer, bringing the rolls together, transferring a circuit pattern onto the flexible substrate, curing the adhesive through non-opaque areas of the circuit pattern, and separating the non-bonded areas. The resulting printed circuit traces are applied from the roll to mounts, and circuit components are applied from a roll to the traces as the mounts move along the line. Additional rolls of printed circuit traces and circuit components may be incorporated, and multi-layer PCBs may be produced. As part of the production line, the finished PCBs may be applied to flat or contoured products.
FILED Tuesday, January 22, 2019
APPL NO 16/253296
ART UNIT 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 13/06 (20130101) Original (OR) Class
H05K 13/0417 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 11191721 Gregory et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Jessica M. Gregory (Butte, Montana);  Jack L. Skinner (Butte, Montana);  Marisa L. Pedulla (Butte, Montana);  M. Katie Hailer (Butte, Montana)
ASSIGNEE(S)
INVENTOR(S) Jessica M. Gregory (Butte, Montana);  Jack L. Skinner (Butte, Montana);  Marisa L. Pedulla (Butte, Montana);  M. Katie Hailer (Butte, Montana)
ABSTRACT Disclosed herein is a particle delivery system comprising electrospun nanofiber comprised of coaxial fiber with a microfluidic core. Iron-doped apatite nanoparticles (IDANPs) have demonstrated a unique influence over phage killing of bacteria, whereby, IDANP-exposed bacterial cultures experience 2× the bacterial death as controls. IDANPs consist of hydroxyapatite (HA) doped with iron. HA is a mineral known to be biocompatible and analogous to the inorganic constituent of mammalian bone and teeth and has been approved by the Food and Drug Administration (FDA) for many applications in medicine and dentistry. Previous work has shown that for IDANPs to enhance antibacterial activity of phage to the greatest extent, bacterial cultures should be exposed to IDANPs for 1 hr prior to phage introduction. Biocompatible polymer materials which encase IDANPs and/or phage can be used to disseminate IDANPs and/or phage in a controlled manner into a physiological system for treatment of bacterial infection. When components of said materials contain micro- or nano-scale components, high surface-to-volume ratio for treatment delivery is garnered.
FILED Thursday, May 23, 2019
APPL NO 16/421108
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 25/10 (20130101)
A01N 25/34 (20130101)
A01N 63/00 (20130101)

Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General
A23L 3/34635 (20130101)

Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages
A23V 2002/00 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/70 (20130101)
A61K 9/0092 (20130101) Original (OR) Class
A61K 35/76 (20130101)
A61K 47/02 (20130101)
A61K 47/34 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2795/00031 (20130101)
C12N 2795/00032 (20130101)

Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons
D01D 5/0007 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191724 He et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
APPLICANT(S) BRANDEIS UNIVERSITY (Waltham, Massachusetts)
ASSIGNEE(S) BRANDEIS UNIVERSITY (Waltham, Massachusetts)
INVENTOR(S) Hongjian He (Waltham, Massachusetts);  Bing Xu (Newton, Massachusetts)
ABSTRACT The present invention relates to a branched peptide that includes a first peptide chain and a second peptide chain having its C-terminal amino acid covalently linked to a sidechain of an amino acid residue of the first peptide chain, wherein the first peptide chain includes a plurality of aromatic amino acids and, optionally, an aromatic group linked to an amino terminus of the first peptide chain; and the second peptide chain includes a plurality of hydrophilic amino acids and an enzyme cleavage site. Pharmaceutical compositions containing the branched peptide and one or more therapeutic agents in an aqueous medium are disclosed, where the branched peptides form micelle structures in the aqueous medium. Methods of using the pharmaceutical composition to deliver therapeutic agents, and for treating various disease conditions are also described.
FILED Tuesday, September 18, 2018
APPL NO 16/648295
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/1075 (20130101) Original (OR) Class
A61K 31/704 (20130101)
A61K 47/42 (20130101)
A61K 47/6907 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 7/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191773 Kahne et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts);  Ohio State Innovation Foundation (Columbus, Ohio)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts);  The Ohio State University (Columbus, Ohio)
INVENTOR(S) Daniel E. Kahne (Cambridge, Massachusetts);  Michael D. Mandler (Cambridge, Massachusetts);  Vadim Baidin (Cambridge, Massachusetts);  Natividad Ruiz (Columbus, Ohio)
ABSTRACT This invention features new compositions and methods that are useful in treating a host with a Gram-negative bacterial infection. Combination therapies comprising an aminocoumarin compound and a polymyxin compound are disclosed, including certain combinations that exhibit synergistic effects. Furthermore, aminocoumarin compounds are described having altered inhibition of DNA gyrase in Gram-negative bacteria and/or the ability to target the transport proteins responsible for assembling lipopolysaccharide in the outer membrane of Gram-negative bacteria.
FILED Monday, July 16, 2018
APPL NO 16/631717
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7048 (20130101)
A61K 31/7056 (20130101) Original (OR) Class
A61K 38/12 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191774 Mitragotri et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Samir Mitragotri (Lexington, Massachusetts);  Marta Broto (Barcelona, Spain);  Kathryn M. Camacho (Los Angeles, California);  Stefano Menegatti (Raleigh, North Carolina)
ABSTRACT Compounds and pharmaceutical formulations containing these compounds are described. Also described are methods of making and using the compounds. The compounds include nucleobases, nucleobase analogues, or combinations thereof. In one embodiment, a nucleobase analogue is combined with doxorubicin and encapsulated within a liposome for use in inhibiting or preventing the growth of cancer cells. Further described are pharmaceutical compositions containing two or more therapeutically active agents encapsulated within a vesicle, such as a liposome, wherein the molar ratio of the agents provides a synergistic therapeutic effect.
FILED Wednesday, November 23, 2016
APPL NO 15/779232
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/1273 (20130101)
A61K 31/506 (20130101)
A61K 31/513 (20130101)
A61K 31/7072 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11192266 Schimmels et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
National Robotics Initiative (NRI)
APPLICANT(S) Marquette University (Milwaukee, Wisconsin)
ASSIGNEE(S) Marquette University (Milwaukee, Wisconsin)
INVENTOR(S) Joseph M. Schimmels (Milwaukee, Wisconsin);  Andrew Bernhard (Milwaukee, Wisconsin);  Jacob Rice (Milwaukee, Wisconsin)
ABSTRACT A variable stiffness actuator comprises a flexure plate which comprises a first cantilevered beam that extends inwards from an outer periphery of the flexure plate. A housing and the flexure plate rotatable about a common joint axis. A first contactor is pivotably secured at a revolute joint to the housing. The first contactor rotates about the revolute joint at a first rotation axis. The first rotation axis offset on the housing from the joint axis. The first contactor engages the first cantilevered beam at a variable angle about the rotation axis to adjust a stiffness of a mechanical connection between the flexure plate and the housing.
FILED Friday, April 14, 2017
APPL NO 16/092661
ART UNIT 3658 — Material and Article Handling
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 9/126 (20130101)
B25J 9/1005 (20130101)
B25J 17/00 (20130101)
B25J 17/0241 (20130101)
B25J 19/068 (20130101) Original (OR) Class

Springs; Shock-absorbers; Means for Damping Vibration
F16F 1/22 (20130101)

Gearing
F16H 49/001 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11192292 Fernandez-Nieves et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida);  Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida);  Georigia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Alberto Fernandez-Nieves (Atlanta, Georgia);  Thomas Ettor Angelini (Gainesville, Florida);  Ya-Wen Chang (Atlanta, Georgia);  Samantha M. Marquez (Midlothian, Virginia)
ABSTRACT A method or apparatus for three-dimensionally printing. The method may comprise causing a phase change in a region of the first material by applying focused energy to the region using a focused energy source, and displacing the first material with a second material. The apparatus may comprise a container configured to hold a first material, a focused energy source configured to cause a phase change in a region of the first material by applying focused energy to the region, and an injector configured to displace the first material with a second material. The first material may comprise a yield stress material, which is a material exhibiting Herschel-Bulkley behavior. The yield stress material may comprise a soft granular gel. The second material may comprise one or more cells.
FILED Friday, December 04, 2015
APPL NO 15/533222
ART UNIT 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/40 (20170801)
B29C 64/106 (20170801) Original (OR) Class
B29C 64/153 (20170801)
B29C 64/209 (20170801)
B29C 64/259 (20170801)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2023/06 (20130101)
B29K 2033/08 (20130101)
B29K 2033/26 (20130101)
B29K 2105/0061 (20130101)
B29K 2105/251 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
B33Y 70/00 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11192915 Cummins et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) Christopher C. Cummins (Dorchester, Massachusetts);  Scott Shepard (Somerville, Massachusetts)
ABSTRACT Metaphosphate compounds can directly phosphorylate other compounds to provide easy synthetic access to phosphorylated compounds, including cyclic phosphate compounds.
FILED Thursday, July 04, 2019
APPL NO 16/503551
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/098 (20130101)
C07F 9/65746 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 19/10 (20130101)
C07H 19/20 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11192929 Harris et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
NIH Office of the Director (NIHOD)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Reuben S. Harris (St. Paul, Minnesota);  Hideki Aihara (Roseville, Minnesota)
ABSTRACT Materials and methods for using modified Cas9-APOBEC fusion polypeptides for targeted modification of specific DNA sequences are provided herein.
FILED Friday, December 08, 2017
APPL NO 15/836598
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 14/4703 (20130101) Original (OR) Class
C07K 2319/80 (20130101)
C07K 2319/85 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/102 (20130101)
C12N 15/1082 (20130101)
C12N 2310/20 (20170501)

Enzymes
C12Y 302/02027 (20130101)
C12Y 305/04005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11192994 Leventis et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Aerogel Technologies, LLC (Glendale, Wisconsin)
ASSIGNEE(S) Aerogel Technologies, LLC (Boston, Massachusetts)
INVENTOR(S) Nicholas Leventis (Rolla, Missouri);  Chariklia Sotiriou-Leventis (Rolla, Missouri);  Sudhir Mulik (North Wales, Pennsylvania)
ABSTRACT Porous three-dimensional networks of polyurea and porous three-dimensional networks of carbon and methods of their manufacture are described. In an example, polyurea aerogels are prepared by mixing an triisocyanate with water and a triethylamine to form a sol-gel material and supercritically drying the sol-gel material to form the polyurea aerogel. Subjecting the polyurea aerogel to a step of pyrolysis may result in a three dimensional network having a carbon skeleton, yielding a carbon aerogel. The density and morphology of polyurea aerogels can be controlled by varying the amount of isocyanate monomer in the initial reaction mixture. A lower density in the aerogel gives rise to a fibrous morphology, whereas a greater density in the aerogel results in a particulate morphology. Polyurea aerogels described herein may also exhibit a reduced flammability.
FILED Thursday, April 04, 2019
APPL NO 16/374958
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/00 (20170801)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 18/18 (20130101)
C08G 18/302 (20130101)
C08G 18/792 (20130101)
C08G 2110/0091 (20210101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 9/02 (20130101) Original (OR) Class
C08J 2205/026 (20130101)
C08J 2375/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193111 Steinmetz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) Nicole F. Steinmetz (Cleveland, Ohio);  Amy M. Wen (Cleveland, Ohio)
ABSTRACT Virus particle multimers and methods of making and using such virus particle multimer are described. Virus particle multimers are constructed by preparing a plurality of asymmetrically functionalized virus particles bearing one or more functional groups and contacting the asymmetrically functionalized virus particles with a first linker molecule that reacts with the functional groups to form a virus particle multimer that includes a plurality of asymmetrically functionalized virus particles connected by the linker molecule. The asymmetrically functionalized virus particles are typically prepared by attaching the virus particles to a support surface to allow asymmetrical functionalization to be introduced.
FILED Friday, December 27, 2013
APPL NO 14/761444
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101) Original (OR) Class
C12N 2770/32023 (20130101)
C12N 2770/32051 (20130101)
C12N 2770/32142 (20130101)
C12N 2810/856 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193149 Lynch et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
APPLICANT(S) DUKE UNIVERSITY (Durham, North Carolina)
ASSIGNEE(S) DUKE UNIVERSITY (Durham, North Carolina)
INVENTOR(S) Michael David Lynch (Durham, North Carolina);  Zhixia Ye (Raleigh, North Carolina)
ABSTRACT The present disclosure provides compositions and methods for rapid production of chemicals in genetically engineered microorganisms in a large scale. Also provided herein is a high-throughput metabolic engineering platform enabling the rapid optimization of microbial production strains. The platform, which bridges a gap between current in vivo and in vitro bio-production approaches, relies on dynamic minimization of the active metabolic network.
FILED Wednesday, October 23, 2019
APPL NO 16/661027
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/001 (20130101)
C12N 9/0006 (20130101)
C12N 9/0008 (20130101)
C12N 9/0016 (20130101)
C12N 9/0051 (20130101)
C12N 9/1025 (20130101)
C12N 15/746 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/42 (20130101) Original (OR) Class
C12P 13/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193513 Staack et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Physics (PHY)
APPLICANT(S) The Texas A and M University System (College Station, Texas)
ASSIGNEE(S) The Texas A and M University System (College Station, Texas)
INVENTOR(S) David Staack (College Station, Texas);  Xin Tang (College Station, Texas)
ABSTRACT In an embodiment, the present disclosure pertains to a cavitation generation device that includes a dactyl plunger rotatable about an axis between an open position and a closed position and a propus socket having a channel. The propus socket is rigidly mounted below the dactyl plunger, and the dactyl plunger is received into the propus socket when the dactyl plunger is in the closed position. The cavitation generation device can also include a torsion spring that biases the dactyl plunger into contact with the propus socket. In another embodiment, the present disclosure pertains to a method of inducing a cavitation including biasing a dactyl plunger via a torsion spring, and rotating the dactyl plunger, by action of the torsion spring, into a propus socket. The propus socket includes a nozzle-shaped channel. The method further includes ejecting a socket cavity volume through the nozzle-shaped channel thereby inducing a cavitation event.
FILED Thursday, July 18, 2019
APPL NO 16/515885
ART UNIT 3753 — Fluid Handling and Dispensing
CURRENT CPC
Fluid Dynamics, i.e Methods or Means for Influencing the Flow of Gases or Liquids
F15D 1/007 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193829 Shaltout et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of the Army (DOA)
Army Research Office (ARO)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Amr Mohammad E Shaltout (West Lafayette, Indiana);  Alexander V. Kildishev (West Lafayette, Indiana);  Vladimir M Shalaev (West Lafayette, Indiana);  Jingjing Liu (West Lafayette, Indiana)
ABSTRACT A circular dichroism spectrometer which comprises a metasurface. The metasurface has a plurality of anisotropic antennas configured to simultaneously spatially separate LCP and RCP spectral components from an incoming light beam. An optical detector array is included which detects the LCP and RCP spectral components. A transparent medium is situated between the metasurface and the optical detector array.
FILED Monday, July 20, 2020
APPL NO 16/932834
ART UNIT 2886 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/0224 (20130101)
G01J 3/0256 (20130101)
G01J 3/447 (20130101) Original (OR) Class
G01J 3/2803 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/19 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193884 Frenkel et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOEOS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Research Foundation for The State University of New York (Albany, New York)
ASSIGNEE(S) The Research Foundation for The State University of New York (Albany, New York)
INVENTOR(S) Anatoly Frenkel (Great Neck, New York);  Janis Timosenko (Upton, New York)
ABSTRACT A method of supervised machine learning-based spectrum analysis information, using a neural network trained with spectrum information, to identify a specified feature of a given material, a system for supervised machine learning-based spectrum analysis, and a method of training a neural network to analyze spectrum data. The method of supervised machine learning-base spectrum analysis comprises inputting into the neural network spectrum data obtained from a sample of the given material; and the neural network processing the spectrum data, in accordance with the training of the neural network, and outputting one or more values for the specified feature of the sample of the material. In an embodiment, the training set of data includes x-ray absorption spectroscopy data for the given material. In an embodiment, the training set of data includes electron energy loss spectra (EELS) data.
FILED Tuesday, July 02, 2019
APPL NO 16/460117
ART UNIT 2884 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/3103 (20130101) Original (OR) Class

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 20/00 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193906 Anderson et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Evan Anderson (Minneapolis, Minnesota);  Philippe Buhlmann (Minneapolis, Minnesota);  Sujay Chopade (Minneapolis, Minnesota);  Marc Hillmyer (Minneapolis, Minnesota);  Tim Lodge (Minneapolis, Minnesota)
ABSTRACT An electrode and a method of making an electrode includes treating polymers that contain functional groups, which by surface functionalization, such as hydrolysis, ozone treatment or carbon-carbon double-bond oxidation to produce hydroxyl functional groups on the surface. Reacting methacryloyl chloride with the resulting hydroxyl functional groups thereby providing a reactive surface. Photopolymerizing or thermal polymerization of crosslinked acrylate or methacrylate polymers on the reactive surface to produce a membrane covalently bonded to the underlying substrate. In addition such an electrode can also be produced on a polystyrene substrate by reacting methacryloyl chloride with the polystyrene substrate and photopolymerizing or thermally polymerizing to produce crosslinked acrylate or methacrylate polymers on the reactive surface to produce a membrane covalently bonded to the underlying polystyrene substrate.
FILED Friday, March 13, 2020
APPL NO 16/818727
ART UNIT 1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 3/28 (20130101)
C08J 3/245 (20130101)
C08J 2367/02 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/3335 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11194059 Frisch et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOEOS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Physics (PHY)
APPLICANT(S) The University of Chicago (Chicago, Illinois)
ASSIGNEE(S) The University of Chicago (Chicago, Illinois)
INVENTOR(S) Henry J. Frisch (Chicago, Illinois);  Evan Angelico (San Marcos, California);  Andrey Elagin (Bolingbrook, Illinois);  Eric Spieglan (Lisle, Illinois)
ABSTRACT Hermetically sealed electronic devices and methods for fabricating the hermetically sealed electronic devices are provided. The devices include a solder sealed vacuum housing. The solder seal is formed using a solder wick having an external solder reservoir. When the reservoir is filled with molten solder, the solder is drawn via capillary action into a precisely defined narrow gap between two components of the housing where it forms an airtight and vacuum-tight seal.
FILED Tuesday, April 07, 2020
APPL NO 16/842261
ART UNIT 2847 — Electrical Circuits and Systems
CURRENT CPC
Measurement of Nuclear or X-radiation
G01T 1/17 (20130101) Original (OR) Class

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/0203 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 5/03 (20130101)
H05K 5/062 (20130101)
H05K 5/063 (20130101)
H05K 5/069 (20130101)
H05K 5/0247 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11194094 Baer et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) Eric Baer (Cleveland Heights, Ohio);  Andy Olah (Spencer, Ohio);  Zhenpeng Li (Shaker Heights, Ohio);  Michael Hore (Shaker Heights, Ohio);  Cong Zhang (Cleveland, Ohio)
ABSTRACT A security marking has a physically unclonable function (PUF) wherein the PUF includes a disordered multilayer photonic crystal structure having an electromagnetic transmission and/or reflection spectrum and/or spectra upon receipt of electromagnetic radiation within a photonic bandgap region of the structure that is unique to the structure.
FILED Friday, June 14, 2019
APPL NO 16/441982
ART UNIT 2886 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/1225 (20130101) Original (OR) Class
G02B 6/02347 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 5/11 (20210101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/3278 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11194834 Smilowitz et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Karen R. Smilowitz (Evanston, Illinois);  George T. Chiampas (Wilmette, Illinois);  Taylor G. Hanken (Chicago, Illinois);  Rachel G. Lin (Evanston, Illinois);  Ryan W. Rose (Evanston, Illinois);  Bruno P. Velazquez (Evanston, Illinois);  Samuel H. Young (Evanston, Illinois)
ABSTRACT Aspects of the present disclosure relate to data visualization, and more specifically, to technology that automatically visualizes various analytics and predictions generated for mass participation endurance events, or other events of interest.
FILED Monday, April 03, 2017
APPL NO 15/478033
ART UNIT 2125 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 3/048 (20130101)
G06F 16/26 (20190101) Original (OR) Class

Computer Systems Based on Specific Computational Models
G06N 3/006 (20130101)
G06N 5/02 (20130101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/04 (20130101)
G06Q 10/06 (20130101)

Image Data Processing or Generation, in General
G06T 17/05 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/22 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 11192667 Gordon et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) U.S.A. as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) Keith L. Gordon (Hampton, Virginia);  Scott R. Zavada (Ypsilanti, Michigan);  Timothy F. Scott (Ann Arbor, Michigan)
ABSTRACT Various embodiments provide multi-layered self-healing materials, capable of repairing puncture damage. The multi-layered self-healing materials, capable of repairing puncture damage of the various embodiments may be constructed by sandwiching a reactive (e.g., oxygen sensitive) liquid monomer formulation between two solid polymer panels, such as a polymer panel of Barex 210 IN (PBG) serving as the front layer panel and a polymer panel of Surlyn® 8940 serving as the back layer panel. The various embodiments may provide methods to produce multi-layered healing polymer systems. The various embodiments may provide a two-tier, self-healing material system that provides a non-intrusive capability to mitigate mid to high velocity impact damage in structures.
FILED Tuesday, December 15, 2015
APPL NO 14/969855
ART UNIT 1787 — Miscellaneous Articles, Stock Material
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 27/08 (20130101)
B32B 27/308 (20130101)
B32B 2255/10 (20130101)
B32B 2255/24 (20130101)
B32B 2307/762 (20130101)
B32B 2307/7244 (20130101)

Cosmonautics; Vehicles or Equipment Therefor
B64G 1/56 (20130101) Original (OR) Class
B64G 6/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11192780 Biaggi-Labiosa et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Azlin M. Biaggi-Labiosa (North Ridgeville, Ohio);  Gary W. Hunter (Oberlin, Ohio)
ABSTRACT A microsensor and its method of manufacture are disclosed based on templated metal or metal oxide nanostructures. The microsensor includes an electrode that in one embodiment may be configured as a first sawtooth patterned electrode having a series of first peaks and first valleys and a second electrode that by be configured as a second sawtooth patterned electrode having a series of second peaks and second valleys where the second peaks generally align with the first peaks of the first electrode. A plurality of templated metal or metal oxide nanostructures connect on one side to the first electrode and on another side to the second electrode, where an electrical property of the microsensor changes in response to exposure to an environment to be monitored.
FILED Monday, March 25, 2019
APPL NO 16/363169
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems
B81C 1/00341 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11194936 Farkas et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) THE BOEING COMPANY (Chicago, Illinois)
ASSIGNEE(S) THE BOEING COMPANY (Chicago, Illinois)
INVENTOR(S) Michael A. Farkas (Hunstiville, Alabama);  Adam L. Griswold (Garden Grove, California);  David R. Mahakian (Anaheim, California);  Justin McFatter (League City, Texas);  Benjamin H. Rothenberg (Costa Mesa, California)
ABSTRACT A system includes a processor and a memory coupled to the processor. The memory stores instructions that cause the processor to determine a first motion envelope of an object. The first motion envelope corresponds to a kinematic envelope of positions of the object which are achievable. The instructions also cause the processor to determine an operational envelope of the object based on an intersection of the first motion envelope and a second motion envelope of the object. The second motion envelope corresponds to a range of motion of the object constrained by dynamic motion limits of the object, and the operational envelope is indicative of a range of motion of the object during operation of the object. The instructions further cause the processor to generate a virtual model of the object based on the operational envelope. The virtual model is used to virtually model operation of the object.
FILED Tuesday, August 21, 2018
APPL NO 16/107738
ART UNIT 2128 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 30/00 (20200101) Original (OR) Class
G06F 2111/20 (20200101)

Image Data Processing or Generation, in General
G06T 17/20 (20130101)
G06T 2210/21 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11195072 Wagner et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) USA as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Raymond S Wagner (Houston, Texas);  David S Hafermalz (Houston, Texas);  Patrick W. Fink (Missouri City, Texas);  Chad Zalkin (Houston, Texas);  Ray Seegmiller (Houston, Texas)
ABSTRACT A method for streaming sensor data from a set of radio-frequency identification (RFID) tags includes determining an initial communication approach to be performed with respect to each RFID tag. The method also includes managing access to the RFID tag by refining the initial communication approach based on records of successes and failures of the initial communication approach. A radio-frequency identification (RFID) system is also disclosed, the system comprising one or more processors and a memory system comprising one or more non-transitory computer-readable media storing instructions that, when executed by at least one of the one or more processors, causes the system to perform operations for streaming sensor data from one or more RFID tags to one or more RFID readers.
FILED Wednesday, February 27, 2019
APPL NO 16/287456
ART UNIT 2699 — Search and Capture Special Detail
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 19/0705 (20130101) Original (OR) Class
G06K 19/0712 (20130101)
G06K 19/0715 (20130101)
G06K 19/0723 (20130101)

Wireless Communication Networks
H04W 52/0229 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11196184 Jordan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Cubic Corporation (San Diego, California)
ASSIGNEE(S) Cubic Corporation (San Diego, California)
INVENTOR(S) Jared W Jordan (Raleigh, North Carolina);  Kenneth J Vanhille (Cary, North Carolina);  Timothy A Smith (Durham, North Carolina);  William Stacy (Blacksburg, Virginia);  Benjamin L Cannon (Apex, North Carolina);  David W Sherrer (Cary, North Carolina)
ABSTRACT Antenna arrays, including a broadband single or dual polarized, tightly coupled radiator arrays.
FILED Tuesday, June 19, 2018
APPL NO 16/076354
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 1/40 (20130101)
H01Q 5/25 (20150115)
H01Q 5/48 (20150115)
H01Q 9/065 (20130101)
H01Q 9/285 (20130101)
H01Q 13/085 (20130101)
H01Q 21/24 (20130101)
H01Q 21/062 (20130101)
H01Q 21/064 (20130101)
H01Q 21/0093 (20130101)
H01Q 25/001 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 11191273 Schrader et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia);  Villanova University (Villanova, Pennsylvania)
ASSIGNEE(S) The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia);  Villanova University (Villanova, Pennsylvania)
INVENTOR(S) Kevin Schrader (Oxford, Mississippi);  Stephen O. Duke (Oxford, Mississippi);  Robert M. Giuliano (Wayne, Pennsylvania)
ABSTRACT Disclosed herein are methods of making (4aR,6S,8aR)-6-((R)-1-hydroxyethyl)-6,8a-dihydropyrano[3,2-b]pyran-2-(4aH)-one (2) and methods of making (4aR,6S,8aR)-6-cyano-6,8a-dihydropyrano-[3,2-b]pyran-2(4aH)-one (4). Other pyranopyrans were also synthesized. Also compositions containing (4aR,6S,8aR)-6-cyano-6,8a-dihydropyrano-[3,2-b]pyran-2(4aH)-one (4) (or other pyranopyrans described herein) and optionally a carrier. In addition, methods for killing microorganisms or weeds on or in an object or area involving contacting the object or area with an effective microorganisms or weeds killing amount of a composition containing (4aR,6S,8aR)-6-cyano-6,8a-dihydropyrano-[3,2-b]pyran-2(4aH)-one (4) (or other pyranopyrans described herein) and optionally a carrier.
FILED Monday, September 23, 2019
APPL NO 16/579065
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 43/90 (20130101) Original (OR) Class

Heterocyclic Compounds
C07D 493/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11191275 Ravishankar et al.
FUNDED BY
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) Sadhana Ravishankar (Tucson, Arizona);  Govindaraj Dev Kumar (Atlanta, Georgia);  Libin Zhu (Tucson, Arizona);  Bibiana Law (Tucson, Arizona)
ASSIGNEE(S) Arizona Board of Regents on Behalf of The University of Arizona (Tucson, Arizona)
INVENTOR(S) Sadhana Ravishankar (Tucson, Arizona);  Govindaraj Dev Kumar (Atlanta, Georgia);  Libin Zhu (Tucson, Arizona);  Bibiana Law (Tucson, Arizona)
ABSTRACT Compositions and methods that utilize a combination of essential oils or other plant-derived extracts or compounds and an emulsifier as an antimicrobial are provided. In some embodiments the compositions further include ozone. In some embodiments, the composition includes one or more plant essential oils, plant extracts, or plant-derived compounds, or combinations thereof, and an emulsifier (such as a saponin). The antimicrobial composition may also include water, peracetic acid, acetic acid, lactic acid, citric acid, and/or hydrogen peroxide. Methods of killing a microorganism, including contacting the microorganism with the disclosed antimicrobial compositions are also provided. The microorganism may be present on a food item or a food contact of non-food contact surface and may be in the form of a biofilm. In some examples, the antimicrobial composition is used one or more times (such as 1 to 5 times).
FILED Thursday, December 05, 2019
APPL NO 16/704950
ART UNIT 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 59/00 (20130101) Original (OR) Class
A01N 65/00 (20130101)
A01N 65/08 (20130101)
A01N 65/22 (20130101)
A01N 65/24 (20130101)
A01N 65/34 (20130101)
A01N 65/36 (20130101)
A01N 65/38 (20130101)
A01N 65/44 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11192913 Jackson et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented The Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Michael A. Jackson (Morton, Illinois);  Neil P. Price (Edelstein, Illinois)
ABSTRACT Disclosed are C-glycoside amine derivatives of the formula:
R—CH2—C(CH3)—NH—R2
wherein R is a saccharide (e.g., as described in U.S. Pat. No. 8,314,219) and R2 is an acyl moiety derived from any ketone of the formula R3—C(O)—R3 wherein R3 is C1 to C22 straight or branched chain hydrocarbon which may be saturated or unsaturated. In addition, a method for making the C-glycoside amine derivatives involving (1) reacting a saccharide (e.g., glucose) C-glycoside ketone with a catalyst (e.g., Rh), about 10 to about 25 fold excess NH3, and an organic solvent (e.g., methanol) to form a saccharide C-glycoside amine, and (2) reacting said saccharide C-glycoside amine with a catalyst (e.g., Rh), an organic solvent (e.g., methanol), and an acyl moiety derived from any ketone of the formula R3—C(O)—R3 wherein R3 is C1 to C22 straight or branched chain hydrocarbon which may be saturated or unsaturated to form said C-glycoside amine derivative.
FILED Monday, January 04, 2021
APPL NO 17/140415
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 1/00 (20130101)
C07H 7/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 11191824 Puckette
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
INVENTOR(S) Michael Puckette (Waterford, Connecticut)
ABSTRACT A method of producing purified FMDV VLPs, comprising contacting cells containing FMDV VLPs with a lysis buffer and allowing the cells to lyse, the lysis buffer comprising 10-20 mM Tris-HCl, 150-200 mM NaCl, 3 mM MgCl2, and 1% Triton X-100, wherein the lysis buffer does not contain EDTA; centrifuging a solution; and removing a supernatant from the solution, the supernatant containing the purified FMDV VLPs.
FILED Thursday, May 20, 2021
APPL NO 17/326023
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/39 (20130101)
A61K 39/135 (20130101) Original (OR) Class
A61K 2039/552 (20130101)
A61K 2039/5258 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2770/32123 (20130101)
C12N 2770/32134 (20130101)
C12N 2770/32151 (20130101)
C12N 2770/32171 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193526 Adrezin et al.
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
INVENTOR(S) Ronald Adrezin (East Lyme, Connecticut);  Michael Daeffler (Washington, District of Columbia);  Michael F. Derrico (Washington, District of Columbia);  Mary Shalane Regan (Groton, Connecticut);  Matthew K. Mothander (Washington, District of Columbia);  Ryan R. Young (Washington, District of Columbia)
ABSTRACT In an example, a compliant shaft enclosure support system for coupling to a shaft enclosure surrounding a shaft includes a bar having a first member slidably coupled to a second member. The bar is oriented along the pitch axis of the shaft. A first bar end of the bar is rotatably connected, around the roll axis and pitch axis of the shaft, to the shaft enclosure at a first connection. A second bar end of the bar is rotatably connected, around the roll axis and pitch axis, to the structure at a second connection. A link is rotatably connected, around the roll axis, at a first link end to the bar, at an intermediate location spaced from the first and second bar ends. The link is rotatably connected, around the pitch axis, at a second link end to the shaft enclosure at a third connection spaced from the first connection.
FILED Tuesday, April 06, 2021
APPL NO 17/223898
ART UNIT 3656 — Material and Article Handling
CURRENT CPC
Marine Propulsion or Steering
B63H 23/34 (20130101)

Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings
F16C 3/02 (20130101)
F16C 3/03 (20130101)
F16C 7/06 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11195967 Kanatzidis et al.
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Mercouri G. Kanatzidis (Wilmette, Illinois);  Yihui He (Evanston, Illinois)
ABSTRACT Methods and devices for detecting incident radiation are provided. The methods and devices use high quality single-crystals of photoactive semiconductor compounds in combination with metal anodes and metal cathodes that provide for enhanced photodetector performance.
FILED Thursday, September 06, 2018
APPL NO 16/644404
ART UNIT 2884 — Optics
CURRENT CPC
Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 11/003 (20130101)
C30B 29/12 (20130101)

Measurement of Nuclear or X-radiation
G01T 1/24 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/032 (20130101)
H01L 31/085 (20130101) Original (OR) Class
H01L 31/0224 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Office of the Director of National Intelligence (ODNI) 

US 11194915 Stolfo et al.
FUNDED BY
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Salvatore J. Stolfo (New York, New York);  Preetam Kumar Dutta (New York, New York)
ABSTRACT Methods, systems, and media for testing insider threat detection systems are provided. In some embodiments, the method comprises: receiving, using a hardware processor, a first plurality of actions in a computing environment that are associated with one of a plurality of user accounts; generating a plurality of models of user behavior based at least in part on the first plurality of actions, wherein each of the plurality of models of user behavior is associated with each of the plurality of user accounts; selecting a model of user behavior from the plurality of models of user behavior, wherein the model of user behavior is associated with a malicious user type; generating a simulated user bot based on the selected model of user behavior; executing the simulated user bot in the computing environment, wherein the simulated user bot injects a second plurality of actions in the computing environment; determining whether an insider threat detection system executing within the computing environment identifies the simulated user bot as a malicious user; and transmitting a notification indicating an efficacy of the insider threat detection system based on the determination.
FILED Monday, April 16, 2018
APPL NO 16/498847
ART UNIT 2446 — Computer Networks
CURRENT CPC
Electric Digital Data Processing
G06F 21/577 (20130101) Original (OR) Class
G06F 2221/034 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/22 (20130101)
H04L 67/306 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11195117 Monroe et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) UNIVERSITY OF MARYLAND (College Park, Maryland);  DUKE UNIVERSITY (Durham, North Carolina);  UNIVERSITY OF BRITISH COLUMBIA (Vancouver, Canada)
ASSIGNEE(S) University of Maryland (College Park, Maryland);  Duke University (Durham, North Carolina);  University of British Columbia (Vancouver, Canada)
INVENTOR(S) Christopher Monroe (Ellicott City, Maryland);  Jungsang Kim (Chapel Hill, North Carolina);  Robert Raussendorf (Vancouver, Canada)
ABSTRACT A modular quantum computer architecture is developed with a hierarchy of interactions that can scale to very large numbers of qubits. Local entangling quantum gates between qubit memories within a single modular register are accomplished using natural interactions between the qubits, and entanglement between separate modular registers is completed via a probabilistic photonic interface between qubits in different registers, even over large distances. This architecture is suitable for the implementation of complex quantum circuits utilizing the flexible connectivity provided by a reconfigurable photonic interconnect network. The subject architecture is made fault-tolerant which is a prerequisite for scalability. An optimal quantum control of multimode couplings between qubits is accomplished via individual addressing the qubits with segmented optical pulses to suppress crosstalk in each register, thus enabling high-fidelity gates that can be scaled to larger qubit registers for quantum computation and simulation.
FILED Friday, December 15, 2017
APPL NO 15/844357
ART UNIT 2896 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/113 (20130101)

Electric Digital Data Processing
G06F 15/76 (20130101)
G06F 2015/768 (20130101)

Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 11193914 Hwang et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland)
ASSIGNEE(S) GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland)
INVENTOR(S) Jeeseong Hwang (Louisville, Colorado);  Christopher Yung (Louisville, Colorado);  Kimberly Ann Briggman (Boulder, Colorado);  John Henry Lehman (Boulder, Colorado)
ABSTRACT A photoacoustic photon meter includes: a photoacoustic generative array including carbon nanotubes disposed in a photoacoustic generating pattern, such that the carbon nanotubes: receive photons comprising optical energy, and produce thermal energy from the optical energy; and a superstratum including a thermally expandable elastomer on which the photoacoustic generative array is fixedly disposed in position on the superstratum to spatially conserve the photoacoustic generating pattern, and such that the superstratum: is optically transparent to the photons; receives the thermal energy from the photoacoustic generative array; expands and contracts in response to receipt of the thermal energy; and produces photoacoustic pressure waves in response to the expansion and contraction, the photoacoustic pressure waves including a photoacoustic intensity and photoacoustic frequency that are based upon an amount of optical pressure applied to the carbon nanotubes by the photons, a spatial photon fluence of the photons, or a spectral photon fluence of photons.
FILED Tuesday, January 28, 2020
APPL NO 16/774646
ART UNIT 2861 — Printing/Measuring and Testing
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 32/158 (20170801)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 29/221 (20130101)
G01N 29/2418 (20130101) Original (OR) Class
G01N 2291/101 (20130101)
G01N 2291/02872 (20130101)
G01N 2291/02881 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 11191851 Tomlinson et al.
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) MUSC Foundation for Research Development (Charleston, South Carolina);  The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia);  The Regents of the University of Colorado, a body corporate (Denver, Colorado);  Universitat de Barcelona (Barcelona, Spain)
ASSIGNEE(S) MUSC Foundation for Research Development (Charleston, South Carolina)
INVENTOR(S) Stephen Tomlinson (Charleston, South Carolina);  V. Michael Holers (Aurora, Colorado);  Pablo Engel (Barcelona, Spain)
ABSTRACT Provided herein, inter alia, are compositions and methods of using the same for detecting complement activation.
FILED Monday, September 16, 2019
APPL NO 16/572260
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/16 (20130101)
A61K 49/0043 (20130101)
A61K 49/0058 (20130101) Original (OR) Class
A61K 51/1009 (20130101)
A61K 51/1018 (20130101)

Peptides
C07K 16/18 (20130101)
C07K 16/2896 (20130101)
C07K 2317/92 (20130101)
C07K 2317/622 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/534 (20130101)
G01N 33/5695 (20130101)
G01N 2469/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 11194636 Flajslik et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) Intel Corporation (Santa Clara, California)
ASSIGNEE(S) Intel Corporation (Santa Clara, California)
INVENTOR(S) Mario Flajslik (Hopkinton, Massachusetts);  Keith D. Underwood (Powell, Texas);  Timo Schneider (Hudson, Massachusetts);  James Dinan (Hudson, Massachusetts)
ABSTRACT Technologies for generating triggered conditional events operations include a host fabric interface (HFI) of a compute device configured to receive an operation execution command message associated with a triggered operation that has been fired, process the received operation execution command message to extract and store argument information from the received operation execution command, and increment an event counter associated with the fired triggered operation. The HFI is further configured to perform a triggered compare-and-generate event (TCAGE) operation as a function of the extracted argument information, determine whether to generate a triggering event, generate the triggering event as a function of the performed TCAGE operation, insert the generated triggered event into a triggered operation queue, and update the value of the event counter. Other embodiments are described herein.
FILED Friday, March 30, 2018
APPL NO 15/941509
ART UNIT 2194 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 9/542 (20130101) Original (OR) Class
G06F 9/544 (20130101)
G06F 9/546 (20130101)
G06F 2209/548 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Non-Profit Organization (NPO) 

US 11191886 Karimov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Non-Profit Organization (NPO)
The Cleveland Clinic Foundation
APPLICANT(S) THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio)
ASSIGNEE(S) THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio)
INVENTOR(S) Jamshid Karimov (Cleveland Hts., Ohio);  Kiyotaka Fukamachi (Mayfield Hts., Ohio);  Ray Dessoffy (Parma, Ohio)
ABSTRACT A device for minimizing obstruction in a medical device that carries fluids includes a housing defining a channel configured to receive and secure a section of the medical device such that the section of the medical device extends coaxially with a central longitudinal axis of the channel. The device also includes components supported in the housing, including a motor, wherein the components are configured to be operated to impart motion to the housing and the attached medical device. The motion is configured to produce oscillatory motion of a frequency sufficient to concentrate shear stresses in a fluid boundary layer adjacent an inner wall of the medical device. The housing and the components supported in the housing are configured and arranged so that a device center of mass lies along or near the longitudinal axis of the channel.
FILED Friday, March 02, 2018
APPL NO 15/910399
ART UNIT 3781 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 2090/701 (20160201)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 1/04 (20130101)
A61M 1/842 (20210501) Original (OR) Class
A61M 25/00 (20130101)
A61M 25/02 (20130101)
A61M 2025/0019 (20130101)
A61M 2205/103 (20130101)
A61M 2205/106 (20130101)
A61M 2205/8206 (20130101)
A61M 2206/16 (20130101)
A61M 2209/10 (20130101)
A61M 2210/101 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 11193593 Chuong
FUNDED BY
APPLICANT(S) United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S) RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S) Conway Chuong (Manchester, Connecticut)
ABSTRACT A hydrostatic seal assembly includes a primary seal configured to maintain a selected gap between the primary seal and a rotating component. The primary seal includes a seal support, a seal shoe, and one or more seal beams operably connecting the seal support to the seal shoe. The one or more seal beams are configured as spring elements integral with the seal shoe to allow radial movement of the seal shoe relative to the seal support. A seal carrier including a radial outer wall is configured to radially position the primary seal. The seal carrier is configured for a non-contact relationship with the seal shoe during operation of the hydrostatic seal assembly.
FILED Tuesday, September 03, 2019
APPL NO 16/558900
ART UNIT 3675 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 11/003 (20130101)

Pistons; Cylinders; Sealings
F16J 15/348 (20130101)
F16J 15/442 (20130101) Original (OR) Class
F16J 15/3468 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11193750 Fertig et al.
FUNDED BY
APPLICANT(S) Honeywell International Inc. (Morris Plains, New Jersey)
ASSIGNEE(S) Honeywell International Inc. (Charlotte, North Carolina)
INVENTOR(S) Chad Fertig (Bloomington, Minnesota);  David Campagna (Westminster, Colorado);  Karl D. Nelson (Plymouth, Minnesota)
ABSTRACT Systems and methods for dynamic optical interferometer locking using entangled photons are provided. In certain embodiments, a system includes an optical source for generating a pair of photons. Also, the system includes first and second emitter/receivers that emit first and second photons towards first and second remote reflectors and receive reflected first and second photons along first and second optical paths. Additionally, the system includes a mode combiner for combining the reflected first photon and second photon into a first and second output port. Moreover, the system includes a coarse adjuster that performs coarse adjustments and a fine adjuster that performs fine adjustments to the first and second optical paths. Further, the system includes a plurality of photodetectors that detect photons from the first and second output ports. Additionally, the system includes a processor that controls the coarse and fine adjustments based on received signals from the photodetectors.
FILED Wednesday, July 22, 2020
APPL NO 16/936294
ART UNIT 2877 — Optics
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 9/02007 (20130101) Original (OR) Class
G01B 11/043 (20130101)
G01B 2290/70 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 19/23 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11195107 Jiang et al.
FUNDED BY
APPLICANT(S) HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Qin Jiang (Oak Park, California);  Kang-Yu Ni (Calabasas, California);  Tsai-Ching Lu (Thousand Oaks, California)
ABSTRACT Described is a system for predicting future social activity. The system extracts social activities from spatial-temporal social network data collected in a first time period ranging from hours to days to capture spatial structures of social activities in a graph network representation. A graph matching technique is applied over a set of spatial-temporal social network data collected in a second time period ranging from weeks to months to capture temporal structures of the social activities. A spatial-temporal structure of each social activity is represented as an activity core, where each activity core is defined as active nodes that participate in the social activity with a frequency over a predetermined threshold over the second time period. For each activity core, the system computes statistics of the social activity and uses the statistics to generate a prediction of future behaviors of the social activity.
FILED Thursday, December 05, 2019
APPL NO 16/705219
ART UNIT 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 5/02 (20130101)
G06N 5/04 (20130101) Original (OR) Class

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 50/01 (20130101)
G06Q 50/265 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/18 (20130101)
H04L 67/22 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, December 07, 2021.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2021/details-patents-20210427.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital