FedInvent™ Patents
Patent Details for Tuesday, December 21, 2021
This page was updated on Tuesday, December 21, 2021 at 09:39 PM GMT
Department of Health and Human Services (HHS)
| US 11202449 | Belfort et al. |
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| FUNDED BY |
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| APPLICANT(S) | RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York); HEALTH RESEARCH, INC. (Menands, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York); Health Research, Inc. (Menands, New York) |
| INVENTOR(S) | Georges Belfort (Albany, New York); C. Seth Pearson (Albany, New York); Brian Murray (Haverhill, Massachusetts); Pankaj Sakharam Karande (Troy, New York); Jun Ha Kwak (Troy, New York); Kathleen A. McDonough (Albany, New York); Zachary Andrew Kloos (New Haven, Connecticut) |
| ABSTRACT | Disclosed herein are novel anti-microbial peptides with inhibitory activity against M. tuberculosis and streptococcus bacteria. Additionally, a method for designing novel anti-microbial peptides is disclosed. |
| FILED | Tuesday, May 14, 2019 |
| APPL NO | 16/411652 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 43/38 (20130101) A01N 63/50 (20200101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/10 (20130101) A61K 45/06 (20130101) Peptides C07K 7/08 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11202589 | Albuquerque et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| ASSIGNEE(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| INVENTOR(S) | Romulo Albuquerque (Lexington, Kentucky); Nicholas Bell (Lexington, Kentucky); Paras Vora (Lexington, Kentucky) |
| ABSTRACT | A system and method for assessing blood flow include: an ocular lens; a light source; a digital video camera; a biosensor; a trigger; and a computer. The ocular lens is for viewing a fundus of an eye. The light source is for illuminating the fundus. The digital video camera is for imaging the fundus. The biosensor is for sensing a pulse waveform. The computer is configured for: recording input frames and pulse waveform data in response to an input from the trigger; defining a low-pass frequency and a high-pass frequency from the pulse waveform data; stabilizing the input frames; enhancing contrast of the input frames; separating the input frames into sub-channels; conducting eulerian video magnification for color amplification using the inputs of image sampling rate, the low-pass frequency, the high-pass frequency, and an amplification factor; reconstructing the sub-channels into output frames; and combining the output frames with the input frames. |
| FILED | Friday, November 30, 2018 |
| APPL NO | 16/206039 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/0041 (20130101) A61B 3/0083 (20130101) A61B 3/145 (20130101) A61B 3/1233 (20130101) A61B 3/1241 (20130101) A61B 5/318 (20210101) A61B 5/02416 (20130101) A61B 5/6821 (20130101) A61B 5/7257 (20130101) A61B 5/14555 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 5/009 (20130101) G06T 5/40 (20130101) G06T 5/50 (20130101) G06T 2207/10016 (20130101) G06T 2207/20021 (20130101) G06T 2207/20056 (20130101) G06T 2207/20104 (20130101) G06T 2207/20212 (20130101) G06T 2207/30041 (20130101) G06T 2207/30104 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11202590 | Delgado Alonso et al. |
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| FUNDED BY |
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| APPLICANT(S) | Intelligent Optical Systems, Inc. (Torrance, California) |
| ASSIGNEE(S) | Intelligent Optical Systems, Inc. (Torrance, California) |
| INVENTOR(S) | Jesus Delgado Alonso (Torrance, California); Robert Lieberman (Torrance, California); David Berry (Torrance, California) |
| ABSTRACT | Disclosed is a system which adds biochemical sensitivity to a standard biopsy needle such that the practitioner is provided immediate feedback on the metabolism and physiology of tissue in the local environment. Disclosed is a sensor integrated biopsy device for in situ and real time tissue analysis. The sensor integrated biopsy (SIB) needle system will enable biopsy teams to measure local tissue biochemistry in real time during biopsy procedures, adding a valuable new set of parameters to augment and extend conventional image-guided procedures. |
| FILED | Thursday, June 01, 2017 |
| APPL NO | 15/610822 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1459 (20130101) Original (OR) Class A61B 5/6848 (20130101) A61B 5/14532 (20130101) A61B 10/0233 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11202596 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Peng-Sheng Chen (Indianapolis, Indiana); Lan S. Chen (Indianapolis, Indiana) |
| ABSTRACT | A system and methods utilizing electrical stimulation to achieve a desired therapeutic effect are provided. In one aspect, a method for controlling nerve activity in a subject is provided. The method includes receiving input indicating a desired therapeutic effect for at least one neural structure of a subject, and selecting, based on the input received, an electrical stimulation configured to achieve the desired therapeutic effect. The method also includes controlling a sympathetic nerve activity in the subject by delivering the electrical stimulation using electrodes positioned proximate to nerves innervating the subject's skin. |
| FILED | Wednesday, January 17, 2018 |
| APPL NO | 16/479094 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/24 (20210101) Original (OR) Class A61B 5/725 (20130101) A61B 5/4035 (20130101) A61B 5/4041 (20130101) A61B 5/4836 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0456 (20130101) A61N 1/0476 (20130101) A61N 1/0551 (20130101) A61N 1/36031 (20170801) A61N 1/36034 (20170801) A61N 1/36057 (20130101) A61N 1/36114 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11202602 | Rajapakse et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); New York University (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); NEW YORK UNIVERSITY (New York, New York) |
| INVENTOR(S) | Chamith Sudesh Rajapakse (Cherry Hill, New Jersey); Gregory Chang (New York, New York) |
| ABSTRACT | Methods, systems, and computer readable media for non-invasively predicting patient-specific mechanical competence at an anatomical site. In some examples, a method includes receiving images from the anatomical site of a patient; using computational analysis of the images to simulate mechanical loading at the anatomical site; and generating, based on the analysis, an indication of stiffness, strength, resilience or toughness under the mechanical loading conditions. |
| FILED | Monday, December 03, 2018 |
| APPL NO | 16/208054 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/1072 (20130101) A61B 5/4504 (20130101) Original (OR) Class A61B 6/032 (20130101) A61B 6/505 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 30/40 (20180101) G16H 50/20 (20180101) G16H 50/30 (20180101) G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11202603 | Frederick et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cleveland Medical Devices Inc. (Cleveland, Ohio) |
| ASSIGNEE(S) | Cleveland Medical Devices Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Craig A Frederick (Solon, Ohio); Hani Kayyali (Shaker Heights, Ohio); Robert N. Schmidt (Ft. Myers, Florida); Brian M. Kolkowski (Leroy, Ohio) |
| ABSTRACT | The various embodiments of the method of the present invention include a method to improving or expanding the capacity of a sleep analysis unit or laboratory, a method sleep analysis testing a patient admitted for diagnosis or treatment of another primary medical condition while being treated or diagnosed for that condition, a method of sleep analysis testing a patient that cannot be easily moved or treated in a sleep analysis unit or laboratory and other like methods. |
| FILED | Friday, October 11, 2019 |
| APPL NO | 16/599330 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0006 (20130101) A61B 5/0022 (20130101) A61B 5/087 (20130101) A61B 5/369 (20210101) A61B 5/486 (20130101) A61B 5/4815 (20130101) Original (OR) Class A61B 5/6831 (20130101) A61B 5/7282 (20130101) A61B 5/14552 (20130101) A61B 2560/0214 (20130101) A61B 2560/0475 (20130101) A61B 2562/0219 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11202759 | Huebsch et al. |
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| FUNDED BY |
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| APPLICANT(S) | Nathaniel D. Huebsch (Colma, California); Christopher M. Madl (Vestal, New York); Kangwon Lee (Lexington, Massachusetts); Maria M. Xu (Morgantown, West Virginia); David J. Mooney (Sudbury, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Nathaniel D. Huebsch (Colma, California); Christopher M. Madl (Vestal, New York); Kangwon Lee (Lexington, Massachusetts); Maria M. Xu (Morgantown, West Virginia); David J. Mooney (Sudbury, Massachusetts) |
| ABSTRACT | The invention provides compositions and methods to form pores in situ within hydrogels following hydrogel injection. Pores formed in situ via degradation of sacrificial porogens within the surrounding hydrogel facilitate recruitment or release of cells. Disclosed herein is a material that is not initially porous, but which becomes macroporous over time. |
| FILED | Thursday, October 06, 2011 |
| APPL NO | 13/877572 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1652 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/20 (20130101) A61L 27/20 (20130101) A61L 27/26 (20130101) A61L 27/38 (20130101) A61L 27/48 (20130101) A61L 27/48 (20130101) A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/58 (20130101) A61L 2300/414 (20130101) A61L 2400/06 (20130101) Compositions of Macromolecular Compounds C08L 5/04 (20130101) C08L 5/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11202773 | Hu |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| ASSIGNEE(S) | University of Houston System (Houston, Texas) |
| INVENTOR(S) | Ming Hu (Bellaire, Texas) |
| ABSTRACT | Drugs have been designed and developed with a structural motif allowing local bioavailability in the target organ but that are not broadly distributed at a concentration sufficient to illicit toxic side effects in non-targeted organs. The structural motif subjects the compound to be rapidly metabolized by metabolic enzymes before reaching the non-targeted organs. |
| FILED | Wednesday, April 20, 2016 |
| APPL NO | 15/568195 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/415 (20130101) A61K 31/4155 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11202801 | Roybal et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California, UCSF (San Francisco, California) |
| INVENTOR(S) | Kole T. Roybal (San Francisco, California); Raymond Liu (San Francisco, California); Iowis Zhu (San Francisco, California) |
| ABSTRACT | The present disclosure generally relates to, inter alia, a new class of receptors engineered to modulate transcriptional regulation in a ligand-dependent manner. Particularly, the new receptors, even though derived from Notch, do not require the Notch negative regulatory regions previously believed to be essential for the functioning of the receptors. In addition, the new receptors described herein incorporate an extracellular oligomerization domain to promote oligomer formation of the chimeric receptors. The disclosure also provides compositions and methods useful for producing such receptors, nucleic acids encoding same, host cells genetically modified with the nucleic acids, as well as methods for modulating an activity of a cell and/or for the treatment of various health conditions such as cancers. |
| FILED | Tuesday, March 30, 2021 |
| APPL NO | 17/217618 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/00 (20130101) A61K 2039/505 (20130101) A61K 2039/5156 (20130101) A61K 2039/5158 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/705 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 16/32 (20130101) C07K 16/2803 (20130101) C07K 16/2878 (20130101) C07K 2317/53 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/622 (20130101) C07K 2319/03 (20130101) C07K 2319/30 (20130101) C07K 2319/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11202809 | Bailey et al. |
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| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Antoinette Bailey (Pasadena, California); Sarkis K. Mazmanian (Porter Ranch, California); Paul H. Patterson (Altadena, California) |
| ABSTRACT | Some embodiments include bacterial species for use in treatment of one or more autism spectrum disorder (ASD), and/or schizophrenia symptoms in a subject in need thereof. The subject in need thereof can have a gut microbiota signature characteristic of an adult. The bacterial species can include Bacteroides (e.g., B. fragilis, B. thetaiotaomicron, and/or B. vulgatus), and/or Enterococcus (e.g., E. faecalis, E. faecium, E. hirae, E. avium, E. durans, E. gallinarum, or E. casseliflavus). Upon treatment, one or more ASD-related behaviors can be improved in the subject. |
| FILED | Friday, May 01, 2020 |
| APPL NO | 16/865001 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) A61K 35/741 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11202817 | Lin et al. |
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| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Gang Lin (Forest Hills, New York); Carl Nathan (Larchmont, New York); Pradeep K. Singh (New York, New York) |
| ABSTRACT | The compounds of the present invention are represented by the following compounds having Formula I: where the substituents R1, R4, L, M, X, Y, and s are as defined herein. The compounds of the present invention are also represented by the following compounds having Formula (Ia), Formula (Ib), or Formula (Ic): where the substituents R1-R4, Rx, Ry, X, Y, and s are as defined herein. These compounds are used in the treatment of cancer, immunologic disorders, autoimmune disorders, neurodegenerative disorders, or inflammatory disorders or for providing immunosuppression for transplanted organs or tissues. |
| FILED | Wednesday, August 12, 2015 |
| APPL NO | 15/504951 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/42 (20130101) A61K 31/165 (20130101) A61K 38/02 (20130101) A61K 38/05 (20130101) Original (OR) Class Acyclic or Carbocyclic Compounds C07C 237/06 (20130101) C07C 237/12 (20130101) C07C 237/22 (20130101) C07C 271/22 (20130101) C07C 311/14 (20130101) C07C 311/19 (20130101) C07C 2601/02 (20170501) Heterocyclic Compounds C07D 209/18 (20130101) C07D 261/18 (20130101) Peptides C07K 5/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11202818 | Socolovsky et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Merav Socolovsky (Brookline, Massachusetts); Allon M. Klein (Brookline, Massachusetts); Samuel Wolock (Cambridge, Massachusetts); Betsabeh K. Tusi (Shrewsbury, Massachusetts); Yung Hwang (Worcester, Massachusetts); Caleb Weinreb (Newton, Massachusetts) |
| ABSTRACT | In certain aspects, disclosed herein are novel compositions and methods related to either the enhancement or inhibition of erythropoiesis that are useful, for example, in the treatment of anemia or erythrocytosis. |
| FILED | Thursday, September 14, 2017 |
| APPL NO | 16/332879 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/407 (20130101) A61K 31/437 (20130101) A61K 31/497 (20130101) A61K 31/506 (20130101) A61K 31/519 (20130101) A61K 31/541 (20130101) A61K 31/5377 (20130101) A61K 38/20 (20130101) A61K 38/1816 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11202823 | Scott et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Evan A. Scott (Northfield, Illinois); Chyung-Ru Wang (Evanston, Illinois); Shaobin Shang (Evanston, Illinois); Dina Kats (Evanston, Illinois) |
| ABSTRACT | Provided herein are subunit vaccine compositions comprising a nanocarrier and a lipid antigen, a peptide antigen or combinations thereof that elicit bother a CD1-restricted and an MHC-restricted T cell response in a subject. Methods for making and using the subunit vaccine compositions are also provided. |
| FILED | Friday, April 03, 2020 |
| APPL NO | 16/839861 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/51 (20130101) A61K 39/04 (20130101) Original (OR) Class A61K 2039/54 (20130101) A61K 2039/543 (20130101) A61K 2039/55588 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11202824 | Khurana |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Silver Spring, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Silver Spring, Maryland) |
| INVENTOR(S) | Surender Khurana (Clarksburg, Maryland) |
| ABSTRACT | Isolated peptides comprising one or more antigenic sites of filovirus glycoprotein and methods of their use and production are disclosed. Nucleic acid molecules encoding the peptides are also provided. In several embodiments, the peptides can be used to induce an immune response to filovirus glycoprotein, such as Zaire ebolavirus glycoprotein, in a subject, for example, to treat or prevent infection of the subject with the virus. |
| FILED | Tuesday, October 31, 2017 |
| APPL NO | 16/346009 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/6081 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2760/14122 (20130101) C12N 2760/14134 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2469/20 (20130101) G01N 2800/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11202830 | Barouch |
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| FUNDED BY |
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| APPLICANT(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Dan H. Barouch (Newton, Massachusetts) |
| ABSTRACT | Described are N332 glycan-dependent antibodies for treating human immunodeficiency virus (HIV) in a subject that is infected with HIV and that is receiving antiretroviral therapy (ART). |
| FILED | Thursday, August 08, 2019 |
| APPL NO | 16/535921 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) Original (OR) Class A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) Peptides C07K 16/1045 (20130101) C07K 16/1063 (20130101) C07K 2317/76 (20130101) C07K 2317/94 (20130101) C07K 2317/565 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16111 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11202834 | Palermo et al. |
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| FUNDED BY |
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| APPLICANT(S) | RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Edmund Francis Palermo (Delmar, New York); Anthony Richard D'Amato (Troy, New York); Ryan J. Gilbert (Cohoes, New York); Samuel Ellman (Troy, New York) |
| ABSTRACT | The poly(pro-drug) material includes one or more alternating therapeutic compounds and biodegradable hydrocarbyl groups. The therapeutic compounds and biodegradable hydrocarbyl groups are separated by cleavable linker compounds. The therapeutic compounds, such as estrogen, curcumin, and fingolimod, include a plurality of substitutable functional groups that provide reaction sites for complexing with the cleavable linkers and in turn one or more polymers, such that the poly(pro-drug) material ends up composed of the therapeutic compound itself. In aqueous media and at physiological temperature and pH, the poly(pro-drug) materials degrade to release the therapeutic compounds from the material with a zero-order release profile. Advantageously, the poly(pro-drug) materials release the therapeutic compounds on time scales of years. The poly(pro-drug) materials also exhibit reduced to allow for prolonged implantation within a patient. These materials are enticing for a myriad of biomedical applications, including veterinary medicine, cancer treatments, birth control, and hormone replacement therapy. |
| FILED | Wednesday, October 16, 2019 |
| APPL NO | 17/285544 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/565 (20130101) A61K 47/55 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11202840 | Duan et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE CURATORS OF THE UNIVERSITY OF MISSOURI (Columbia, Missouri) |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Dongsheng Duan (Columbia, Macau); Yi Lai (Columbia, Missouri); Junling Zhao (Columbia, Missouri); Yongping Yue (Columbia, Missouri) |
| ABSTRACT | Synthetic nucleic acids encoding mini and microdystrophin genes comprising the membrane binding motifs or domains of the R10-R11-R12 region are provided. Also provided are vectors, host cells, and related methods of using the same to treat a subject suffering from Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD) or X-linked dilated cardiomyopathy (XLDC), or for ameliorating one or more adverse effects of DMD, BMD, or XLDC. Also provided are a fusion protein comprising a nNOS binding domain of dystrophin R16-R17 that is operably linked to a syntrophin PDZ domain and synthetic nucleic acids comprising the same that can be used to treat subjects with diseases characterized by loss of sarcolemmal neuronal nitric oxide synthase (nNOS) activity. |
| FILED | Wednesday, June 21, 2017 |
| APPL NO | 16/311236 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 35/00 (20130101) A61K 35/28 (20130101) A61K 38/00 (20130101) A61K 48/00 (20130101) A61K 48/005 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/14 (20180101) Peptides C07K 14/4716 (20130101) C07K 2319/00 (20130101) C07K 2319/01 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0663 (20130101) C12N 15/62 (20130101) C12N 15/85 (20130101) C12N 15/86 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11202850 | Bowlin et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE UNIVERSITY OF MEMPHIS RESEARCH FOUNDATION (Memphis, Tennessee); THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Memphis, Tennessee) |
| ASSIGNEE(S) | The University of Memphis Research Foundation (Memphis, Tennessee); The University of Tennessee Research Foundation (Memphis, Tennessee) |
| INVENTOR(S) | Gary L. Bowlin (Memphis, Tennessee); Allison E. Fetz (Memphis, Tennessee); Marko Z. Radic (Memphis, Tennessee) |
| ABSTRACT | As described below, the present invention features compositions and methods for inhibiting inflammation in connection with an acellular template (e.g., an electrospun template). In one embodiment, the template is impregnated with an agent (e.g., N-α-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide (Cl-amidine)) that inhibits a peptidylarginine deaminase (e.g., PAD4). |
| FILED | Monday, March 11, 2019 |
| APPL NO | 16/298891 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) Original (OR) Class A61L 27/54 (20130101) A61L 27/58 (20130101) A61L 2300/41 (20130101) A61L 2300/204 (20130101) A61L 2300/434 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/06 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/20 (20130101) C08K 5/29 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) C08L 67/04 (20130101) C08L 67/04 (20130101) C08L 89/06 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0007 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 1/10 (20130101) D01F 6/625 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11202888 | Paul, Jr. et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cook Medical Technologies LLC (Bloomington, Indiana) |
| ASSIGNEE(S) | Cook Medical Technologies LLC (Bloomington, Indiana) |
| INVENTOR(S) | Ram H Paul, Jr. (Bloomington, Indiana); Richard Swift (South Bend, Indiana); Shuo Yang (West Lafayette, Indiana); Tracy Willis (Bloomington, Indiana); Gary Neff (Bloomington, Indiana) |
| ABSTRACT | The disclosure relates to medical devices and methods of assembling medical devices, such as MRI-compatible interventional wireguides. An example of a wireguide includes a series of individual segments, a plurality of connectors, and a plurality of spacers. Each segment in the series of individual segments has a first end and a second end. Each connector of the plurality of connectors joins adjacent segments in the series of individual segments to one another such that a first end of a first segment and a second end of a second segment in the series of individual segments are attached to a connector of the plurality of connectors. A spacer of the plurality of spacers is disposed between each pair of adjacent segments in the series of individual segments. Each of the segments in the series of individual segments is electrically insulated from an adjacent segment in the series of individual segments. |
| FILED | Monday, December 03, 2018 |
| APPL NO | 16/207391 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/09 (20130101) Original (OR) Class A61M 2025/09083 (20130101) A61M 2025/09133 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/285 (20130101) G01R 33/286 (20130101) G01R 33/3685 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203014 | Funk et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | William E. Funk (Evanston, Illinois); Thomas W. McDade (Evanston, Illinois); Andrew Unger (Bethlehem, Pennsylvania) |
| ABSTRACT | Disclosed are devices, kits, compositions, and methods for collecting, transporting, and detecting toxicants, pathogens, and biomarkers in a biological sample. The devices, kits, compositions and methods may be utilized to collect and transport dried blood samples from a skin prick and detect toxicants, pathogens, and biomarkers in the dried blood samples. |
| FILED | Monday, August 05, 2019 |
| APPL NO | 16/532336 |
| ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/151 (20130101) A61B 5/15105 (20130101) A61B 5/15142 (20130101) A61B 5/150022 (20130101) A61B 5/150305 (20130101) A61B 5/150358 (20130101) A61B 5/150412 (20130101) A61B 5/150503 (20130101) A61B 5/150755 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 1/52 (20190801) B01L 3/5023 (20130101) Original (OR) Class B01L 3/5055 (20130101) B01L 2200/141 (20130101) B01L 2200/185 (20130101) B01L 2200/0689 (20130101) B01L 2300/021 (20130101) B01L 2300/069 (20130101) B01L 2300/126 (20130101) B01L 2300/0681 (20130101) B01L 2300/0816 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/84 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203576 | Betts et al. |
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| FUNDED BY |
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| APPLICANT(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida) |
| ASSIGNEE(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida) |
| INVENTOR(S) | Brian Betts (Tampa, Florida); Said M. Sebti (Tampa, Florida); Harshani Lawrence (Tampa, Florida); Nicholas Lawrence (Tampa, Florida); Claudio Anasetti (Tampa, Florida); Joseph Pidala (Tampa, Florida) |
| ABSTRACT | Disclosed herein are compounds and methods for reducing the risk of developing, preventing, or treating graft versus host disease (GVHD) in a subject. The compounds can concurrently block Aurora kinase A and JAK2 signal transduction which synergistically suppresses alloreactive human T-cells in vitro, prevents xenogeneic graft-versus-host disease without impairing anti-tumor responses, and promotes the development and suppressive potency of CD39+ inducible Treg. In certain aspects, disclosed are compounds of Formula I-V. |
| FILED | Monday, March 13, 2017 |
| APPL NO | 16/083681 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/505 (20130101) A61K 31/506 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 239/48 (20130101) Original (OR) Class C07D 401/12 (20130101) C07D 403/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203582 | Wang |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| INVENTOR(S) | Weidong Wang (Edmond, Oklahoma) |
| ABSTRACT | Novel 3-(N-piperidinyl)methyl benzamide derivatives are disclosed. The compounds can be used in treating diseases and conditions which are associated with abnormal cell function related to endoplasmic reticulum (ER) stress. For example, the compounds can be used as suppressors of ER stress-induced pancreatic β-cell dysfunction and death, for example in the treatment of diabetes. |
| FILED | Friday, June 15, 2018 |
| APPL NO | 16/621154 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 233/65 (20130101) Heterocyclic Compounds C07D 207/09 (20130101) C07D 211/34 (20130101) C07D 317/68 (20130101) C07D 319/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203588 | Burkart et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Michael D. Burkart (San Diego, California); James J. La Clair (San Diego, California); Sachin Dhar (Pleasanton, California); Justin C. Hammons (San Diego, California); Brian Leon (San Diego, California) |
| ABSTRACT | There are provided inter alia stable anti-cancer compounds and splice modulators and methods of synthesis and use thereof. |
| FILED | Friday, March 10, 2017 |
| APPL NO | 16/083419 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 309/10 (20130101) C07D 405/06 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/1804 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203596 | Silverman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Richard B. Silverman (Winnetka, Illinois); Matthew J. Moschitto (Evanston, Illinois) |
| ABSTRACT | Disclosed are compound and methods of using the compounds for modulating ornithine aminotransferase (OAT) activity. The disclosed compound are characterized as analogs of 3-amino-4-(propan-2-ylidene)cyclopentane-1-carboxylic acid which may be formulated as therapeutic agents for treating diseases and disorders associated with ornithine aminotransferase (OAT) activity such as hepatocellular carcinoma and other cancers. |
| FILED | Tuesday, February 25, 2020 |
| APPL NO | 16/800753 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) Acyclic or Carbocyclic Compounds C07C 229/48 (20130101) C07C 233/03 (20130101) Heterocyclic Compounds C07D 471/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203598 | El-Deiry et al. |
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| FUNDED BY |
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| APPLICANT(S) | Institute For Cancer Research (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Institute For Cancer Research (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Wafik S. El-Deiry (Philadelphia, Pennsylvania); Shengliang Zhang (Philadelphia, Pennsylvania); Liz J. Hernandez Borrero (Philadelphia, Pennsylvania) |
| ABSTRACT | The disclosure generally relates to compounds, compositions, and methods for the treatment of cancer by restoring the P53 pathway signaling to repress cancer cell growth. In particular, the compounds comprise Formula I: or a pharmaceutically acceptable salt thereof, wherein: R1 is hydrogen or a haloalkyl group; and each R2, R3, R4, R5, R6, and R7 is, independently, hydrogen, halogen, hydroxyl, cyano, alkyl, alkenyl, alkoxy, substituted or unsubstituted aryl, heteroaryl, phosphate, phosphoramidate, amine, alkylamino, acylamino, aminoalkoxy, or alkylthio. |
| FILED | Wednesday, January 23, 2019 |
| APPL NO | 16/255204 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/522 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 473/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203608 | Lippard et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Stephen J. Lippard (Washington, District of Columbia); Omer Yilmaz (Cambridge, Massachusetts); Fang Wang (Cambridge, Massachusetts); Jonathan Braverman (Cambridge, Massachusetts) |
| ABSTRACT | Platinum-containing compounds are generally described. For example, compounds of Formula (II) are generally described. Inventive compositions and uses thereof are also described. For example, methods of treating cancer in a subject comprising administering to the subject a therapeutically effective amount of a compound of Formula (II) are generally described. |
| FILED | Friday, April 03, 2020 |
| APPL NO | 16/839629 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/0093 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203616 | Hughes et al. |
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| FUNDED BY |
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| APPLICANT(S) | NovoBiotic Pharmaceuticals, LLC (Cambridge, Massachusetts) |
| ASSIGNEE(S) | NovoBiotic Pharmaceuticals, LLC (Cambridge, Massachusetts) |
| INVENTOR(S) | Dallas Hughes (Bolton, Massachusetts); Amy Spoering (Waltham, Massachusetts); Aaron J. Peoples (Somerville, Massachusetts); Losee Lucy Ling (Arlington, Massachusetts); Anthony Nitti (Lexington, Massachusetts); William Millett (Worcester, Massachusetts); Ashley Zullo (Cambridge, Massachusetts); Kim Lewis (Newton, Massachusetts); Slava Epstein (Dedham, Massachusetts); Alysha Desrosiers (Medford, Massachusetts); Catherine Achorn (Cambridge, Massachusetts); Kelly Demeo (Brookline, Massachusetts) |
| ABSTRACT | The present invention relates generally to novel depsipeptides, to methods for the preparation of the novel depsipeptides, to pharmaceutical compositions comprising the novel depsipeptides; and to methods of using the novel depsipeptides to treat or inhibit various disorders. |
| FILED | Friday, March 30, 2018 |
| APPL NO | 16/500470 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Peptides C07K 11/02 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203617 | Steichen et al. |
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| FUNDED BY |
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| APPLICANT(S) | International AIDS Vaccine Initiative (New York, New York); The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | INTERNATIONAL AIDS VACCINE INITIATIVE (New York, New York); THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| INVENTOR(S) | Jon Steichen (La Jolla, California); Dan Kulp (New York, New York); Xiaozhen Hu (La Jolla, California); Sergey Menis (New York, New York); William Schief (La Jolla, California); Sebastian Raemisch (La Jolla, California) |
| ABSTRACT | The invention relates to PGT121-germline-targeting designs, trimer stabilization designs, combinations of those two, trimers designed with modified surfaces helpful for immunization regimens, other trimer modifications and on development of trimer nanoparticles and methods of making and using the same. |
| FILED | Monday, September 24, 2018 |
| APPL NO | 16/139173 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/21 (20130101) A61K 2039/575 (20130101) Peptides C07K 14/005 (20130101) C07K 14/162 (20130101) Original (OR) Class C07K 2319/20 (20130101) C07K 2319/21 (20130101) C07K 2319/70 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203626 | Bishai et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland); Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | William R. Bishai (Baltimore, Maryland); John R. Murphy (Tilghman, Maryland); Laurene Cheung (Baltimore, Maryland); Shashank Gupta (Frederick, Maryland); Cynthia K. Bullen (Baltimore, Maryland) |
| ABSTRACT | The present invention is a DNA expression vector comprising: a toxP; a mutant toxO that blocks Fe-mediated regulation of gene expression; and a DNA sequence encoding a protein, wherein the toxP and the mutant toxO regulate expression of the DNA segment encoding the protein. It is preferred that DNA expression vectors of the present invention include DNA sequences encoding a signal peptide so that a protein expressed is attached to the signal peptide prior to processing. Novel proteins are produced off of the DNA expression vector of the present invention. |
| FILED | Monday, September 11, 2017 |
| APPL NO | 16/611243 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/34 (20130101) C07K 14/55 (20130101) Original (OR) Class C07K 2319/02 (20130101) C07K 2319/21 (20130101) C07K 2319/33 (20130101) C07K 2319/034 (20130101) C07K 2319/55 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/77 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203636 | Testani et al. |
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| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut); Novo Nordisk A/S (Bagsværd, Denmark) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut); Novo Nordisk A/S (Bagsvaerd, Denmark) |
| INVENTOR(S) | Jeffrey Testani (Guilford, Connecticut); Veena Rao (Derby, Connecticut); Rahul Kakkar (Weston, Massachusetts); Madhav N. Devalaraja (Acton, Massachusetts); Chih-Hung Lo (Rockville, Maryland) |
| ABSTRACT | The present disclosure provides methods of treating diuretic resistance by administering an IL-6 antagonist to patients who require diuresis. In typical embodiments, the patient has heart failure. Optionally, the patient has elevated urine levels of IL-6, plasma levels of IL-6, or both urine and plasma levels of IL-6. |
| FILED | Thursday, February 01, 2018 |
| APPL NO | 16/482038 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/248 (20130101) Original (OR) Class C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203739 | Finley et al. |
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| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York); The Rockefeller University (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan-Kettering Cancer Center (New York, New York); The Rockefeller University (New York, New York) |
| INVENTOR(S) | Lydia W. S. Finley (New York, New York); Bryce W. Carey (New York, New York); Craig B. Thompson (New York, New York); C. David Allis (New York, New York) |
| ABSTRACT | Disclosed herein are compositions, systems, and methods for modulating proliferation, differentiation and pluripotency of cells. |
| FILED | Tuesday, April 07, 2015 |
| APPL NO | 15/302560 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/194 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0606 (20130101) Original (OR) Class C12N 5/0696 (20130101) C12N 2500/30 (20130101) C12N 2501/727 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203758 | Zhao et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Yangbing Zhao (Lumberton, New Jersey); Jiangtao Ren (Philadelphia, Pennsylvania); Xiaojun Liu (Wallingford, Pennsylvania); Carl H. June (Merion Station, Pennsylvania) |
| ABSTRACT | The present invention relates to compositions and methods for generating a modified T cell with a nucleic acid capable of downregulating endogenous gene expression selected from the group consisting of TCR α chain, TCR β chain, beta-2 microglobulin and FAS further comprising a nucleic acid encoding a modified T cell receptor (TCR) comprising affinity for a surface antigen on a target cell or an electroporated nucleic acid encoding a chimeric antigen receptor (CAR). Also included are methods and pharmaceutical compositions comprising the modified T cell for adoptive therapy and treating a condition, such as an autoimmune disease. |
| FILED | Wednesday, April 25, 2018 |
| APPL NO | 15/962379 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 35/26 (20130101) A61K 39/001102 (20180801) A61K 2039/5156 (20130101) A61K 2039/5158 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 37/06 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) C12N 15/1138 (20130101) Original (OR) Class C12N 2310/10 (20130101) C12N 2310/20 (20170501) C12N 2501/48 (20130101) C12N 2501/515 (20130101) C12N 2501/599 (20130101) C12N 2501/998 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203759 | Kiley et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Patricia J. Kiley (Middleton, Wisconsin); Dan M. Park (Dublin, California) |
| ABSTRACT | The invention provided herein relates to sequence determinants that elicit certain levels of gene expression and methods for obtaining engineered ligand-responsive gene switches comprising these sequence determinants. More particularly, the invention provided herein relates to molecular building blocks (i.e., discrete nucleotide sequences), synthetic ligand-responsive gene switches comprising an assembly of these molecular building blocks, and methods of using synthetic ligand-responsive gene switches as customizable and controllable expression systems and sensors. |
| FILED | Thursday, September 07, 2017 |
| APPL NO | 15/698302 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) C12N 15/70 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203767 | Anderson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Daniel G. Anderson (Framingham, Massachusetts); Robert Alexander Wesselhoeft (Boston, Massachusetts); Piotr S. Kowalski (Allston, Massachusetts) |
| ABSTRACT | Methods and constructs for engineering circular RNA are disclosed. In some embodiments, the methods and constructs comprise a vector for making circular RNA, the vector comprising the following elements operably connected to each other and arranged in the following sequence: a.) a 5′ homology arm, b.) a 3′ group I intron fragment containing a 3′ splice site dinucleotide, c.) optionally, a 5′ spacer sequence, d.) a protein coding or noncoding region, e.) optionally, a 3′ spacer sequence, f.) a 5′ Group I intron fragment containing a 5′ splice site dinucleotide, and g.) a 3′ homology arm, the vector allowing production of a circular RNA that is translatable or biologically active inside eukaryotic cells. Methods for purifying the circular RNA produced by the vector and the use of nucleoside modifications in circular RNA produced by the vector are also disclosed. |
| FILED | Wednesday, March 03, 2021 |
| APPL NO | 17/191697 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 16/2803 (20130101) C07K 2317/31 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 15/85 (20130101) Original (OR) Class C12N 2015/859 (20130101) C12N 2015/8518 (20130101) C12N 2800/70 (20130101) C12N 2800/107 (20130101) C12N 2800/202 (20130101) C12N 2840/55 (20130101) C12N 2840/60 (20130101) C12N 2840/203 (20130101) C12N 2999/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203768 | Uchida et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Naoya Uchida (Rockville, Maryland); Juan J. Haro Mora (Washington, District of Columbia); John F. Tisdale (Washington, District of Columbia) |
| ABSTRACT | The invention is directed to a system comprising a lentivirus vector particle which encodes at least one guide RNA sequence that is complementary to a first DNA sequence in a host cell genome, a Cas9 protein, and optionally a donor nucleic acid molecule comprising a second DNA sequence. The invention also is directed to a method of altering a DNA sequence in a host cell using such a system, where the host cell can be in a human and the altered DNA can be of the human β-globin gene. The invention also is directed to a fusion protein comprising a Cas9 protein and a cyclophilin A (CypA) protein. The invention also is directed to sequences of vectors that can be used in the system and method. |
| FILED | Monday, April 02, 2018 |
| APPL NO | 15/942673 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 7/645 (20130101) C07K 14/155 (20130101) C07K 14/4717 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/90 (20130101) C12N 15/11 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 15/102 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) C12N 2740/15011 (20130101) C12N 2740/15023 (20130101) C12N 2740/15032 (20130101) C12N 2740/15041 (20130101) C12N 2740/15042 (20130101) C12N 2740/15043 (20130101) C12N 2740/16011 (20130101) C12N 2740/16023 (20130101) C12N 2740/16031 (20130101) C12N 2740/16041 (20130101) C12N 2740/16043 (20130101) C12N 2800/80 (20130101) Enzymes C12Y 502/01008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203772 | Xu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yongmei Xu (Durham, North Carolina); Jian Liu (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Yongmei Xu (Durham, North Carolina); Jian Liu (Chapel Hill, North Carolina) |
| ABSTRACT | Methods for preparing synthetic heparins are provided. Synthetic heparin compounds, including ultralow molecular weight heparin compounds are provided. Also provided are methods of chemoenzymatically synthesizing structurally homogeneous ultra-low molecular weight heparins. Heparin compounds provided herein can have anticoagulant activity. |
| FILED | Thursday, December 22, 2011 |
| APPL NO | 13/996930 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Polysaccharides; Derivatives Thereof C08B 37/0075 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1051 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/04 (20130101) C12P 19/18 (20130101) Original (OR) Class C12P 19/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203787 | Abate et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Adam R. Abate (Daly City, California); Dennis Jay Eastburn (Burlingame, California); Adam R. Sciambi (San Francisco, California) |
| ABSTRACT | Methods for the detection of components from biological samples are provided. In certain aspects, the methods may be used to detect and/or quantify specific components in a biological sample, such as tumor cells (e.g., circulating tumor cells). Systems and devices for practicing the subject methods are also provided. |
| FILED | Thursday, October 18, 2018 |
| APPL NO | 16/164707 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/0807 (20130101) B01F 5/0652 (20130101) B01F 13/0062 (20130101) B01F 13/0076 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502784 (20130101) B01L 7/52 (20130101) B01L 2200/0652 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2300/0883 (20130101) B01L 2300/1822 (20130101) B01L 2400/0415 (20130101) B01L 2400/0487 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/686 (20130101) C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6844 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2537/143 (20130101) C12Q 2563/159 (20130101) C12Q 2563/159 (20130101) C12Q 2565/629 (20130101) C12Q 2600/16 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11204353 | Zhao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PTM BIO LLC (Chicago, Illinois) |
| ASSIGNEE(S) | PTM Biolab Inc. (Hangzhou, China PRC) |
| INVENTOR(S) | Yingming Zhao (Chicago, Illinois); Lunzhi Dai (Chicago, Illinois) |
| ABSTRACT | The invention provides an isolated peptide comprising a lysine 2-hydroxyisobutyrylation site, a lysine 2-hydroxyisobutyrylation specific affinity reagent that specifically binds to the peptide, and a method for detecting protein lysine 2-hydroxyisobutyrylation in a sample using the reagent. |
| FILED | Friday, January 18, 2019 |
| APPL NO | 16/251822 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/18 (20130101) C07K 16/44 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6875 (20130101) Original (OR) Class G01N 2440/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11204354 | Tarca et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WAYNE STATE UNIVERSITY (Detroit, Michigan); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| ASSIGNEE(S) | Wayne State University (Detroit, Michigan); The United States of America, as Represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Adi L. Tarca (South Lyon, Michigan); Piya Chaemsaithong (Shatin, China Hong Kong); Tinnakorn Chaiworapongsa (Grosse Pointe Park, Michigan); Sonia S. Hassan (Novi, Michigan); Roberto Romero (Grosse Pointe, Michigan) |
| ABSTRACT | Kits and methods to distinguish between false and true labor are provided. The kits and methods can utilize differences in abundance and/or differences in the rate of change in abundance of B7-H2, SORC2, TF, C1-Esterase Inhibitor, Ran, IMD-H1 and/or PGAM1, as markers of true labor. |
| FILED | Monday, November 07, 2016 |
| APPL NO | 15/773980 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Enzymes C12Y 101/01205 (20130101) C12Y 504/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/543 (20130101) G01N 33/689 (20130101) Original (OR) Class G01N 2333/4727 (20130101) G01N 2800/368 (20130101) Electric Digital Data Processing G06F 17/18 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) G16B 5/20 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11204355 | Liebler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Daniel C. Liebler (Brentwood, Tennessee); Lisa J. Zimmerman (Franklin, Tennessee); Hyoungjoo Lee (Brentwood, Tennessee); Carlos A. Morales Betanzos (Brentwood, Tennessee); Douglas B. Johnson (Nashville, Tennessee) |
| ABSTRACT | The present disclosure relates generally to the analysis of immune checkpoint proteins involved in cancer. In particular, the present disclosure provides material and methods for determining abundance ratios of various immune checkpoint proteins (e.g., PD-1, PD-L1, and PD-L2) present in a biospecimen sample based on quantification of peak area using mass spectrometry analysis. The methods disclosed herein provide an alternative platform for diagnosing and treating cancer, especially in cases limited by ineffective antibody recognition. |
| FILED | Tuesday, February 20, 2018 |
| APPL NO | 15/899970 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2818 (20130101) C07K 16/2827 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6848 (20130101) G01N 33/6893 (20130101) Original (OR) Class G01N 33/57492 (20130101) G01N 2333/70521 (20130101) G01N 2333/70532 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11204398 | Goodwill |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Magnetic Insight, Inc. (Alameda, California); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | MAGNETIC INSIGHT, INC. (Alameda, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Patrick W. Goodwill (Oakland, California) |
| ABSTRACT | A Magnetic Particle Imaging (MPI) system with a magnet configured to generate a magnetic field with a field free line, the magnet integrated with a flux return designed so that a flux path at approximately the center of the field-free line has a first reluctance and a second flux path distal from the center of the field-free line has a second reluctance, and the second reluctance is lower than the first reluctance to facilitate a high fidelity magnetic field and high fidelity field free line. |
| FILED | Wednesday, July 12, 2017 |
| APPL NO | 15/648401 |
| ART UNIT | 2868 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0515 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/72 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/10 (20130101) G01R 33/0213 (20130101) G01R 33/1276 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11204409 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Luonan Wang (Auburn, California); Daniel Stuart Weller (Charlottesville, Virginia); John P. Mugler, III (Charlottesville, Virginia); Craig H. Meyer (Charlottesville, Virginia) |
| ABSTRACT | Systems and methods for reconstructing a motion-compensated magnetic resonance image are presented. In certain implementations, a computer-implemented method is provided. The method may include a plurality of operations, including receiving a set of k-space data from a magnetic resonance imaging device, dividing the set of k-space data into a plurality of groups, performing a plurality of initialization operations, performing a first iterative process until a first criteria for the first iterative process is achieved for a current scale of motion estimation, performing a second iterative process until a second criteria for the second iterative process is achieved, and outputting a motion-compensated magnetic resonance image reconstructed in accordance with a predetermined scale of motion estimation. |
| FILED | Friday, October 11, 2019 |
| APPL NO | 16/599853 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/58 (20130101) G01R 33/5611 (20130101) G01R 33/5676 (20130101) G01R 33/56308 (20130101) G01R 33/56509 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11205097 | Masse et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | THE UNIVERSITY OF CHICAGO (Chicago, Illinois) |
| INVENTOR(S) | Nicolas Y. Masse (Chicago, Illinois); Gregory D. Grant (Chicago, Illinois); David J. Freedman (Chicago, Illinois) |
| ABSTRACT | A computing device may receive a first set of training data for training an ANN to predict output data for a first task, and may train the ANN with the first set of training data by only adjusting values of weights associated with a first subset of neurons, the first subset selected based on an identity of the first task. The computing device may receive a second, different set of training data for training the ANN to predict output data for a second task, and may train the ANN with the second set of training data by only adjusting values of weights associated with a second subset of neurons, the second subset selected based on an identity of the second task. During training, adjusting of the value of any weight may entail weight stabilization that depends on whether there has been any training for one or more previous tasks. |
| FILED | Tuesday, January 28, 2020 |
| APPL NO | 16/774343 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6228 (20130101) G06K 9/6257 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11202587 | Plaxco et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Kevin Plaxco (Santa Barbara, California); Hui Li (Wuhan, China PRC); Netzahualcoyotl Arroyo Curras (Santa Barbara, California); Di Kang (Glendora, California); Francesco Ricci (Rome, Italy) |
| ABSTRACT | The invention encompasses novel methods of operating electrochemical sensors such as aptamer-based sensors to analyze complex samples, such as flowing whole blood both in vitro or in vivo. In such environments, electrochemical sensors are often subject to drift, which complicates the interpretation of sensor output in terms of target concentration. The method of the invention utilizes a dual-reporter recognition element that generates a first, sensing current that is responsive to target binding and to environmental factors and a second, reference current that is only affected by environmental factors. The reference current provides information about environmentally-induced drift, which allows the drift effect to be subtracted out. By removing drift artifacts, electrochemical sensors may be deployed to analyze complex samples, such as whole blood, in vivo. |
| FILED | Monday, September 25, 2017 |
| APPL NO | 16/336113 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/24 (20210101) A61B 5/0031 (20130101) A61B 5/1473 (20130101) A61B 5/14546 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) C12Q 1/6825 (20130101) C12Q 2525/205 (20130101) C12Q 2545/101 (20130101) C12Q 2545/114 (20130101) C12Q 2565/101 (20130101) C12Q 2565/607 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3275 (20130101) G01N 33/542 (20130101) G01N 33/5438 (20130101) G01N 33/54353 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11202715 | Harshbarger et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Stuart D. Harshbarger (Woodbine, Maryland); James D. Beaty (Wiesbaden, Germany); R. Jacob Vogelstein (Bethesda, Maryland); Nitish V. Thakor (Clarksville, Maryland) |
| ABSTRACT | Methods and systems to interface between physiological devices and a prosthetic device, including to receive a plurality of types of physiological activity signals from a user, decode a user movement intent from each of the plurality of signals types, and fuse the movement intents into a joint decision to control moveable elements of the prosthetic device. |
| FILED | Tuesday, September 24, 2019 |
| APPL NO | 16/580271 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/369 (20210101) A61B 5/398 (20210101) A61B 5/7264 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/54 (20130101) A61F 2/68 (20130101) Original (OR) Class A61F 2/72 (20130101) A61F 2002/5058 (20130101) A61F 2002/5059 (20130101) A61F 2002/5061 (20130101) A61F 2002/5063 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11202840 | Duan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE CURATORS OF THE UNIVERSITY OF MISSOURI (Columbia, Missouri) |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Dongsheng Duan (Columbia, Macau); Yi Lai (Columbia, Missouri); Junling Zhao (Columbia, Missouri); Yongping Yue (Columbia, Missouri) |
| ABSTRACT | Synthetic nucleic acids encoding mini and microdystrophin genes comprising the membrane binding motifs or domains of the R10-R11-R12 region are provided. Also provided are vectors, host cells, and related methods of using the same to treat a subject suffering from Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD) or X-linked dilated cardiomyopathy (XLDC), or for ameliorating one or more adverse effects of DMD, BMD, or XLDC. Also provided are a fusion protein comprising a nNOS binding domain of dystrophin R16-R17 that is operably linked to a syntrophin PDZ domain and synthetic nucleic acids comprising the same that can be used to treat subjects with diseases characterized by loss of sarcolemmal neuronal nitric oxide synthase (nNOS) activity. |
| FILED | Wednesday, June 21, 2017 |
| APPL NO | 16/311236 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 35/00 (20130101) A61K 35/28 (20130101) A61K 38/00 (20130101) A61K 48/00 (20130101) A61K 48/005 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/14 (20180101) Peptides C07K 14/4716 (20130101) C07K 2319/00 (20130101) C07K 2319/01 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0663 (20130101) C12N 15/62 (20130101) C12N 15/85 (20130101) C12N 15/86 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11202843 | Eden et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | J. Gary Eden (Champaign, Illinois); Peter Peng Sun (Urbana, Illinois) |
| ABSTRACT | An air fed mycoplasma device includes an array of elongate microchannels formed in a plastic or ceramic having tolerance to ozone and other radicals formed when plasma is generated from air in the microchannels. The microchannels include inlets configured to accept an air feed, and outlets configured to direct plasma jets toward a surface (which may be flat or internal to a pipe, for example) or object. An array of electrodes within the plastic/ceramic housing is configured to ignite and maintain plasma in the microchannels and is isolated by the dielectric from the microchannels. A supply intake for is configured to providing a plasma medium into the microchannels. |
| FILED | Wednesday, May 16, 2018 |
| APPL NO | 15/981085 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/14 (20130101) Original (OR) Class A61L 9/22 (20130101) A61L 2202/11 (20130101) A61L 2202/15 (20130101) A61L 2202/17 (20130101) A61L 2202/24 (20130101) A61L 2202/25 (20130101) Cleaning in General; Prevention of Fouling in General B08B 1/04 (20130101) B08B 9/04 (20130101) B08B 9/045 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/30 (20130101) C02F 1/72 (20130101) C02F 1/78 (20130101) C02F 2103/003 (20130101) C02F 2103/06 (20130101) C02F 2201/782 (20130101) C02F 2303/04 (20130101) C02F 2303/20 (20130101) C02F 2305/023 (20130101) C02F 2307/14 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/2406 (20130101) H05H 1/2418 (20210501) H05H 1/2437 (20210501) H05H 1/2443 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11202855 | Young et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CYTOSORBENTS CORPORATION (Monmouth Junction, New Jersey) |
| ASSIGNEE(S) | CYTOSORBENTS CORPORATION (Monmouth Junction, New Jersey) |
| INVENTOR(S) | Wei-Tai Young (Hillsborough, New Jersey); Tamaz Guliashvili (Philadelphia, Pennsylvania); Andrew Scheirer (Bethlehem, Pennsylvania); Josh Vichare (New Brunswick, New Jersey); Timothy Kovacs (Allentown, Pennsylvania); Maryann Gruda (Yardley, Pennsylvania); Thomas Golobish (Princeton, New Jersey); Vincent Capponi (Monmouth Junction, New Jersey); Phillip Chan (Cherry Hill, New Jersey) |
| ABSTRACT | This invention discloses methods for reducing physiologic molecules in abnormal levels and/or exogenous toxins in blood from blood by way of an extracorporeal circuit comprising a hollow-fiber filter module and polymer sorbent in combination. |
| FILED | Thursday, March 22, 2018 |
| APPL NO | 16/497982 |
| ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/3475 (20140204) A61M 1/3486 (20140204) Original (OR) Class A61M 1/3663 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11202998 | Colling, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| INVENTOR(S) | Arthur K. Colling, Jr. (Monson, Massachusetts); Benjamin E. Bishop (South Glastonbury, Connecticut); Allison B. Thomas (Hampden, Massachusetts) |
| ABSTRACT | A discharge system includes a mixing vessel and a feedstock input in fluid communication with the mixing vessel. A solvent input is in fluid communication with the mixing vessel. A discharge output is in fluid communication with an outlet of the mixing vessel to discharge effluent. A method for generating turbulence on a liquid surface within a discharge system includes supplying a mixing vessel with feedstock fluid and solvent fluid to generate a liquid mixture and a gas pocket in the mixing vessel. The method includes supplying an impinging solvent fluid through a nozzle extending from a first end of the mixing vessel to generate a roiling surface at an interface between the gas pocket and the liquid mixture and permit uptake of gas from the gas pocket into the liquid mixture. |
| FILED | Monday, March 16, 2020 |
| APPL NO | 16/820693 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 1/0022 (20130101) B01F 1/0027 (20130101) B01F 3/04248 (20130101) B01F 3/04496 (20130101) B01F 3/04737 (20130101) B01F 5/0057 (20130101) B01F 5/0682 (20130101) Original (OR) Class B01F 2201/00 (20130101) Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/08 (20130101) Gas-flow Silencers or Exhaust Apparatus for Machines or Engines in General; Gas-flow Silencers or Exhaust Apparatus for Internal Combustion Engines F01N 3/04 (20130101) F01N 13/12 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 21/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203031 | Albrecht |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | John William Albrecht (Silverdale, Washington) |
| ABSTRACT | Apparatuses and methods related to improving environmental protection and waste collection from application of deposition material using portable systems that are easier for operators to use on surfaces such as ship hulls are provided. Embodiments include a portable and repositionable deposition material applicator enclosure and application system for applying deposition material on a substrate employing non-adherent deposition material waste removal and selective enclosure coupling and decoupling structures or systems employing magnetic and suction or differential pressure based forces. |
| FILED | Tuesday, July 09, 2019 |
| APPL NO | 16/506086 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Spraying Apparatus; Atomising Apparatus; Nozzles B05B 14/30 (20180201) Original (OR) Class Apparatus for Applying Fluent Materials to Surfaces, in General B05C 11/1039 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/06 (20130101) B05D 1/12 (20130101) B05D 2401/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203160 | Vora et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Hitesh D Vora (Stillwater, Oklahoma); Subrata Sanyal (Norco, California) |
| ABSTRACT | Apparatuses and methods are provided that provide adaptive multi-process additive manufacturing systems for monitoring, measuring, and controlling additive manufacturing processes. A first laser (e.g., a fiber laser) is used for melting and consolidating the powder, and a second laser is utilized for dual purpose: (a) for metrology to measure the surface roughness, dimensional accuracy, material properties, etc., and (b) based on the evaluated measurements to take corrective actions (laser ablation, etc.) to attain the desired surface finish and dimensional accuracy. Various elements provide defect detection, defect identification, and defect response actions which remove defect related material or address under print or missing material in a build object. |
| FILED | Friday, March 29, 2019 |
| APPL NO | 16/370871 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/188 (20170801) B29C 64/268 (20170801) B29C 64/393 (20170801) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) B33Y 40/20 (20200101) B33Y 50/02 (20141201) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203385 | Blankespoor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Boston Dynamics, Inc. (Waltham, Massachusetts) |
| ASSIGNEE(S) | Boston Dynamics, Inc. (Waltham, Massachusetts) |
| INVENTOR(S) | Kevin Blankespoor (Arlington, Massachusetts); Alex Perkins (Arlington, Massachusetts); Marco da Silva (Arlington, Massachusetts) |
| ABSTRACT | An example method may include i) determining a first distance between a pair of feet of a robot at a first time, where the pair of feet is in contact with a ground surface; ii) determining a second distance between the pair of feet of the robot at a second time, where the pair of feet remains in contact with the ground surface from the first time to the second time; iii) comparing a difference between the determined first and second distances to a threshold difference; iv) determining that the difference between determined first and second distances exceeds the threshold difference; and v) based on the determination that the difference between the determined first and second distances exceeds the threshold difference, causing the robot to react. |
| FILED | Wednesday, April 24, 2019 |
| APPL NO | 16/393003 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1694 (20130101) Motor Vehicles; Trailers B62D 57/02 (20130101) Original (OR) Class Systems for Controlling or Regulating Non-electric Variables G05D 1/027 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203424 | Darmstadt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Patrick Darmstadt (Claymont, Delaware); Yiyi Zhang (Wallingford, Pennsylvania); Mark J. Robuck (Chadds Ford, Pennsylvania) |
| ABSTRACT | A mechanical power transmission that pivots about an axis to vary an angle between an input shaft and an output shaft. The mechanical power transmission includes an input gear having an input shaft that couples to a drive shaft, an output gear having an output shaft that couples to a tail rotor, a first intermediate gear rotationally coupled to the input gear, and a second intermediate gear rotationally coupled to the output gear. The mechanical power transmission further comprises a shaft that mechanically couples the first intermediate gear with the second intermediate gear, where a centerline of the shaft is coincident with the axis. |
| FILED | Wednesday, March 13, 2019 |
| APPL NO | 16/351971 |
| ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/16 (20130101) B64C 27/22 (20130101) B64C 27/82 (20130101) Original (OR) Class B64C 2027/8236 (20130101) B64C 2027/8272 (20130101) Gearing F16H 57/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203436 | Beckman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Mary Eileen Beckman (West Chester, Pennsylvania); Mark Steven Kuehn (Gilbert, Arizona); Robert Herkimer (Savannah, Georgia) |
| ABSTRACT | A system for cooling a plurality of electrical equipment components inside a mobile platform may include at least one manifold and a plurality of flexible tubing ducts. The manifold may have an outlet, and a plurality of inlet tubing connections in fluid communication with the outlet. The outlet may be coupled to an interface of a cooling system of the platform by exhaust tubing. Each of the flexible tubing ducts may have a proximal end and a distal end. Each proximal end may be selectively connectable to the inlet tubing connections. Each distal end may have an air intake port that is alternatively positionable in two or more thermal dissipation zones of the electrical equipment components for permitting an exhaust profile inside the platform to the interface to be reconfigured based at least in part on respective positions of the electrical equipment components. |
| FILED | Friday, November 22, 2019 |
| APPL NO | 16/693041 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Arrangements of Heating, Cooling, Ventilating or Other Air-treating Devices Specially Adapted for Passenger or Goods Spaces of Vehicles B60H 1/00564 (20130101) B60H 2001/00614 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 13/08 (20130101) Original (OR) Class B64D 47/00 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/2059 (20130101) H05K 7/20572 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203444 | Morrison |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Matthew Morrison (Leonardtown, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Matthew Morrison (Leonardtown, Maryland) |
| ABSTRACT | An arm removal system for removing an arm. The system includes an anvil, and a removal assembly with at least two jackscrews. The arm has an extension radially extending from the arm and an arm outer surface. The arm is disposed within a wedge shaped collet that is disposed within a socket in an aircraft with an aircraft outer surface. The removal assembly includes an extension engaging surface and threaded jackscrew holes for accepting the jackscrews, such that when the jackscrews are tightened within the jackscrew holes, the jackscrews apply force on the anvil and the aircraft outer surface in the direction away from the removal assembly such that the arm is eventually removed entirely from the aircraft. |
| FILED | Tuesday, April 07, 2020 |
| APPL NO | 16/842165 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 19/025 (20130101) Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 5/50 (20170101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203447 | Holmes |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Michael Holmes (Boron, California) |
| ABSTRACT | An electric propulsion module coupled to a spacecraft capable of providing thrust at a level required for multi-burn orbit transfer is disclosed herein. The electric propulsion system includes an electric propulsion thruster, a propellant tank and an energy storage device. In one form the energy storage device is a battery operable to provide sufficient power to maneuver the spacecraft quickly to avoid space debris and/or move to a different orbit through a multi-burn thrust procedure. |
| FILED | Wednesday, February 27, 2019 |
| APPL NO | 16/286719 |
| ART UNIT | 3619 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/007 (20130101) Original (OR) Class B64G 1/242 (20130101) B64G 1/405 (20130101) B64G 1/425 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203525 | Plochowietz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Anne Plochowietz (Palo Alto, California); Matthew Shreve (Mountain View, California) |
| ABSTRACT | Disclosed are methods and systems of controlling the placement of micro-objects on the surface of a micro-assembler. Control patterns may be used to cause phototransistors or electrodes of the micro-assembler to generate dielectrophoretic (DEP) and electrophoretic (EP) forces which may be used to manipulate, move, position, or orient one or more micro-objects on the surface of the micro-assembler. A set of micro-object may be analyzed. Geometric properties of the set of micro-objects may be identified. The set of micro-objects may be divided into multiple sub-sets of micro-objects based on the one or more geometric properties and one or more control patterns. |
| FILED | Monday, December 31, 2018 |
| APPL NO | 16/237360 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 99/002 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/67271 (20130101) H01L 21/67294 (20130101) H01L 24/95 (20130101) H01L 2224/95133 (20130101) H01L 2224/95145 (20130101) H01L 2924/1461 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49133 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203695 | Tuteja et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of The University of Michigan (Ann Arbor, Michigan); The Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson Air Force Base, Ohio) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); The Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson Air Force Base, Ohio) |
| INVENTOR(S) | Anish Tuteja (Ann Arbor, Michigan); Kevin Golovin (Ann Arbor, Michigan); James W. Gose (Ann Arbor, Michigan); Mathew Boban (Ann Arbor, Michigan); Joseph M. Mabry (West Lancaster, California); Marc Perlin (Ann Arbor, Michigan); Steven Ceccio (Dexter, Michigan) |
| ABSTRACT | Durable superhydrophobic components have a superhydrophobic material disposed (e.g., disposed) thereon that exhibits an apparent advancing dynamic contact angle of ≥about 150° and a roll-off angle of about ≤15° for water after at least 100 abrasion cycles. The superhydrophobic material may comprise a low surface energy material and a polymeric material. The superhydrophobic material may be self-healing and capable of recovering its wettability after damage. In yet other aspects, a component comprises a surface that is superhydrophobic and reduces drag in turbulent flow conditions. The surface has an apparent advancing dynamic contact angle of ≥about 150° and a roll-off angle of ≤about 15° for water, and a product of dimensionless roughness (k+) and a higher-pressure contact angle hysteresis of less than or equal to about 5.8. Methods of making such materials are also provided. |
| FILED | Wednesday, September 06, 2017 |
| APPL NO | 16/330987 |
| ART UNIT | 1787 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 27/20 (20130101) B32B 27/283 (20130101) B32B 2255/26 (20130101) B32B 2264/1021 (20200801) B32B 2307/73 (20130101) B32B 2307/554 (20130101) B32B 2307/584 (20130101) B32B 2307/714 (20130101) B32B 2383/00 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/36 (20130101) C08K 3/36 (20130101) C08K 5/549 (20130101) C08K 5/549 (20130101) C08K 9/02 (20130101) C08K 9/02 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/00 (20130101) C09D 5/16 (20130101) C09D 5/1675 (20130101) C09D 5/1675 (20130101) C09D 5/1681 (20130101) Original (OR) Class C09D 7/63 (20180101) C09D 7/63 (20180101) C09D 7/65 (20180101) C09D 7/65 (20180101) C09D 201/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/31 (20150115) Y10T 428/31663 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203696 | Mahoney et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Clare M. Mahoney (Washington, District of Columbia); Richard A. Vaia (Beavercreek, Ohio); Kyoungweon Park (Beavercreek, Ohio) |
| ABSTRACT | The present invention relates to processes for selective reshaping of nanoparticles in three dimensional articles, three dimensional articles produced by such processes, and methods of using such three dimensional articles. As a result of the aforementioned process, such three dimensional articles can have selective tuning that arises, at least in part, from the reshaped nanoparticles found in such articles. Such tuning provides the aforementioned articles with superior performance that can be advantageous in the areas including such as optical filters, multi-functional composites and sensing elements. |
| FILED | Friday, May 17, 2019 |
| APPL NO | 16/415163 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 35/0805 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2105/162 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 70/00 (20141201) B33Y 80/00 (20141201) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/037 (20130101) Original (OR) Class C09D 11/101 (20130101) C09D 11/106 (20130101) C09D 11/107 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203721 | Zoican-Loebick |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PRECISION COMBUSTION, INC. (North Haven, Connecticut) |
| ASSIGNEE(S) | PRECISION COMBUSTION, INC. (North Haven, Connecticut) |
| INVENTOR(S) | Codruta Maria Zoican-Loebick (North Haven, Connecticut) |
| ABSTRACT | A process of removing at least one metal contaminant, such as copper, from a fluid hydrocarbon, for example, crude oil or a liquid hydrocarbon fuel, such as an aviation fuel. The process involves contacting the metal-contaminated fluid hydrocarbon with a sorbent selected from graphene oxide or a functionalized graphene oxide, particularly, a graphene oxide treated with a polycarboxylic acid, such as a saccharide polycarboxylic acid or a salt thereof, examples of which include alginic acid and Group IA and IIA salts thereof. The process removes greater than 99 percent of the metal contaminant without reducing concentrations of advantageous fuel additives, such as, antioxidants, icing inhibitors and corrosion inhibitors. Also described are a purified fluid hydrocarbon composition and a metal contaminant filter system. |
| FILED | Monday, June 29, 2020 |
| APPL NO | 16/914693 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/20 (20130101) B01J 20/3085 (20130101) B01J 20/3202 (20130101) B01J 20/28061 (20130101) B01J 20/28095 (20130101) B01J 2220/46 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 25/003 (20130101) Original (OR) Class C10G 2300/205 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/182 (20130101) C10L 1/226 (20130101) C10L 10/04 (20130101) C10L 2230/081 (20130101) C10L 2230/083 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203726 | Harvey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Benjamin G. Harvey (Ridgecrest, California); Matthew C. Davis (Ridgecrest, California) |
| ABSTRACT | A diamondoid fuel comprising a cage structure including 10, 14, 18, or 22 carbons. The diamondoid fuel also includes one of one to four cyclopropyl groups bonded to the cage structure or two to four functional groups bonded to the cage structure where the functional groups are an alkyl group, an allyl group, a cyclopropyl group, or combinations thereof. Additionally, at least one functional group is an allyl group and at least one functional group is a cyclopropyl group. |
| FILED | Tuesday, March 31, 2020 |
| APPL NO | 16/835639 |
| ART UNIT | 1759 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 43/00 (20130101) Acyclic or Carbocyclic Compounds C07C 2/56 (20130101) C07C 2/86 (20130101) C07C 7/04 (20130101) C07C 7/11 (20130101) C07C 7/14 (20130101) C07C 13/615 (20130101) C07C 22/00 (20130101) Compositions of Macromolecular Compounds C08L 45/00 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/00 (20130101) C10L 1/04 (20130101) Original (OR) Class C10L 10/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203744 | Lynch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| INVENTOR(S) | Michael David Lynch (Durham, North Carolina); Zhixia Ye (Raleigh, North Carolina) |
| ABSTRACT | The present disclosure is related to genetically engineered microbial strains and related bioprocesses for the production of pyruvate and related products. Specifically, the use of dynamically controlled synthetic metabolic valves to reduce the activity of enzymes known to contribute to pyruvate synthesis, leads to increased pyruvate production in a two-stage process rather than a decrease in production. |
| FILED | Friday, June 21, 2019 |
| APPL NO | 16/448292 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) C12N 9/0036 (20130101) C12N 9/0051 (20130101) C12N 9/1025 (20130101) C12N 9/1205 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/40 (20130101) Enzymes C12Y 101/01049 (20130101) C12Y 106/03001 (20130101) C12Y 108/01004 (20130101) C12Y 203/03001 (20130101) C12Y 207/0104 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203767 | Anderson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Daniel G. Anderson (Framingham, Massachusetts); Robert Alexander Wesselhoeft (Boston, Massachusetts); Piotr S. Kowalski (Allston, Massachusetts) |
| ABSTRACT | Methods and constructs for engineering circular RNA are disclosed. In some embodiments, the methods and constructs comprise a vector for making circular RNA, the vector comprising the following elements operably connected to each other and arranged in the following sequence: a.) a 5′ homology arm, b.) a 3′ group I intron fragment containing a 3′ splice site dinucleotide, c.) optionally, a 5′ spacer sequence, d.) a protein coding or noncoding region, e.) optionally, a 3′ spacer sequence, f.) a 5′ Group I intron fragment containing a 5′ splice site dinucleotide, and g.) a 3′ homology arm, the vector allowing production of a circular RNA that is translatable or biologically active inside eukaryotic cells. Methods for purifying the circular RNA produced by the vector and the use of nucleoside modifications in circular RNA produced by the vector are also disclosed. |
| FILED | Wednesday, March 03, 2021 |
| APPL NO | 17/191697 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 16/2803 (20130101) C07K 2317/31 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 15/85 (20130101) Original (OR) Class C12N 2015/859 (20130101) C12N 2015/8518 (20130101) C12N 2800/70 (20130101) C12N 2800/107 (20130101) C12N 2800/202 (20130101) C12N 2840/55 (20130101) C12N 2840/60 (20130101) C12N 2840/203 (20130101) C12N 2999/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203770 | Angenent et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Largus T. Angenent (Tübingen, Germany); Leo Kucek (Lake Mills, Wisconsin) |
| ABSTRACT | Methods and systems to produce product compositions comprising caprylate products using chain-elongating bacteria. For example, the caprylate product in the product composition is n-caprylic acid (C8) and the n-caprylic (C8) to n-caproic (C6) acid ratio is higher than 1:1. These methods use chain elongation towards C8 rather than C6. High n-caprylate productivity and specificity was accomplished by: 1) feeding a substrate with, for example, ethanol as the carbon source or alternatively, a high ethanol-to-acetate ratio as the carbon source; 2) extracting caprylate product(s) (e.g., n-caprylate product) from the bioreactor broth; and 3) acclimating an efficient chain-elongating microbiome. The methods can produce caprylate products such as, for example, n-caprylic acid, which is a higher value chemical than C4 and C6. |
| FILED | Monday, January 06, 2020 |
| APPL NO | 16/735469 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/6409 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203976 | Guardi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Vito Guardi (Stratford, Connecticut); Christopher B. Lyons (West Hartford, Connecticut); Nathan Snape (Tolland, Connecticut) |
| ABSTRACT | A turbine engine includes a compressor section, a combustor in fluid communication with the compressor section, and a turbine section in fluid communication with the combustor. Also included in the turbine engine is a mixing chamber. The mixing chamber is located between the compressor section and the combustor section and the mixing chamber is radially outward of a primary fluid flow path connecting the compressor section, the combustor section, and the turbine section. |
| FILED | Monday, February 24, 2020 |
| APPL NO | 16/798969 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/18 (20130101) F01D 9/065 (20130101) F01D 25/14 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) F02C 6/08 (20130101) F02C 7/18 (20130101) Original (OR) Class F02C 7/185 (20130101) F02C 9/18 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/35 (20130101) F05D 2260/20 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/283 (20130101) F23R 3/286 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11204189 | Sharar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Department of the Army, U.S. Army CCDC Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Darin J. Sharar (Silver Spring, Maryland); Brendan M. Hanrahan (Silver Spring, Maryland) |
| ABSTRACT | A method of cooling includes providing an elastocaloric material; continuously applying a force on the elastocaloric material to cause a continuous mechanical deformation of the elastocaloric material for a predetermined period of time, such that the continuous mechanical deformation creates a solid-to-solid phase transformation in the elastocaloric material; emitting exothermic latent heat from the elastocaloric material to increase a temperature of the elastocaloric material; removing the force from the elastocaloric material upon expiration of the predetermined period of time; and absorbing endothermic latent heat into the elastocaloric material to decrease the temperature of the elastocaloric material and/or an environment adjacent to the elastocaloric material or an electronic/phononic device, etc. |
| FILED | Tuesday, July 02, 2019 |
| APPL NO | 16/459667 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 23/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11204246 | Strandjord et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| INVENTOR(S) | Lee K. Strandjord (Tonka Bay, Minnesota); Norman Gerard Tarleton (Glendale, Arizona); Chuck Croker (Glendale, Arizona) |
| ABSTRACT | Systems and methods are provided to reduce at least one differential harmonics of a resonance tracking modulation in a resonant fiber optic gyroscope (RFOG). The fundamental frequency of the resonance tracking modulation of each of the clockwise and counter clockwise optical signals is substantially identical; however, the amplitude and phase of the Nth harmonic of a clockwise (CW) resonance tracking modulation and the Nth harmonic of a clockwise (CCW) resonance tracking modulation may differ due to non-linearities in the RFOG. Embodiments of the invention diminish, e.g., reduce to zero such vectoral difference. Differential harmonics may be generated at one or more harmonics. |
| FILED | Friday, June 12, 2020 |
| APPL NO | 16/900419 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/721 (20130101) G01C 19/727 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11204320 | Millard et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| ASSIGNEE(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| INVENTOR(S) | John A. Millard (Sahuarita, Arizona); John O. Crawford (Vail, Arizona) |
| ABSTRACT | A transmissometer and method for determining a transmissivity of an atmosphere within a chamber. A chamber contains the atmosphere. A light source generates a test beam and a light detector detects the test beam. A periscope is movable between a first position which allows the test beam to pass through the atmosphere in the chamber and into the light detector and a second position in which the test beam is deflected to pass into the light detector without passing through the atmosphere in the chamber. A processor determines the transmissivity of the atmosphere from a transmissivity measurement for the test beam obtained by the light detector when the periscope is in the first position and a transfer standard obtained at the light detector when the periscope is in the second position. |
| FILED | Thursday, April 23, 2020 |
| APPL NO | 16/856370 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/59 (20130101) Original (OR) Class G01N 2201/12769 (20130101) Optical Elements, Systems, or Apparatus G02B 23/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11204327 | Postelnicu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Eveline Postelnicu (Somerville, Massachusetts); Samarth Aggarwal (Cambridge, Massachusetts); Kazumi Wada (Lexington, Massachusetts); Jurgen Michel (Arlington, Massachusetts); Lionel C. Kimerling (Concord, Massachusetts); Michelle L. Clark (Pelham, New Hampshire); Anuradha M. Agarwal (Weston, Massachusetts) |
| ABSTRACT | A layer of amorphous Ge is formed on a substrate using electron-beam evaporation. The evaporation is performed at room temperature. The layer of amorphous Ge has a thickness of at least 50 nm and a purity of at least 90% Ge. The substrate is complementary metal-oxide-semiconductor (CMOS) compatible and is transparent at Long-Wave Infrared (LWIR) wavelengths. The layer of amorphous Ge can be used as a waveguide in chemical sensing and data communication applications. The amorphous Ge waveguide has a transmission loss in the LWIR of 11 dB/cm or less at 8 μm. |
| FILED | Thursday, November 21, 2019 |
| APPL NO | 16/691007 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/7746 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 6/125 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02592 (20130101) H01L 21/02595 (20130101) H01L 2021/60165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11204468 | Chandrahalim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | US Gov't as represented by Secretary of Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Hengky Chandrahalim (Beavercreek, Ohio); Jonathan Smith (Xenia, Ohio) |
| ABSTRACT | A passive microscopic Fabry-Pérot Interferometer (FPI) sensor includes an optical fiber a three-dimensional microscopic optical structure formed on a cleaved tip of an optical fighter that reflects a light signal back through the optical fiber. The reflected light is altered by refractive index changes in the three-dimensional structure that is subject to at least one of: (i) thermal radiation; and (ii) volatile organic compounds. |
| FILED | Tuesday, December 29, 2020 |
| APPL NO | 17/136552 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 20/00 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/26 (20130101) G01J 3/0218 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/09 (20130101) G01N 21/274 (20130101) G01N 21/8507 (20130101) Optical Elements, Systems, or Apparatus G02B 6/02033 (20130101) G02B 6/3624 (20130101) G02B 6/29358 (20130101) G02B 6/29359 (20130101) Original (OR) Class G02B 2006/12159 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11204838 | Mitsch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Stefan Mitsch (Pittsburgh, Pennsylvania); Andre Platzer (Pittsburgh, Pennsylvania) |
| ABSTRACT | Disclosed herein are techniques to make the synthesized monitoring conditions of partially-observable hybrid systems robust to partial observability of sensor uncertainty and partial controllability due to actuator disturbance. The approach herein shows that the monitoring conditions result in provable safety guarantees with fallback controllers that react to monitor violation at runtime. |
| FILED | Friday, November 15, 2019 |
| APPL NO | 16/685099 |
| ART UNIT | 2128 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 11/1415 (20130101) Original (OR) Class G06F 11/3409 (20130101) G06F 30/27 (20200101) G06F 2201/805 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11205524 | Raman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Chandra Raman (Atlanta, Georgia); Farrokh Ayazi (Atlanta, Georgia) |
| ABSTRACT | Embodiments of the present disclosure relate to atomic beam collimators and, more particularly, to miniaturized coplanar atomic beam collimators. In some examples, an atomic beam collimator may comprise an atomic channel disposed in a substrate. Additional atomic channels may be provided coplanar with the first atomic channel in the substrate. Some examples include a series of cascaded atomic channels, each cascaded atomic channel separated by a gap. The gaps may reduce the off-flux atoms in the output of the atomic collimator. In some examples, a system may comprise an atomic collimator, an atom source, and/or a microelectromechanical system device. These component can be separate devices or can be incorporated into a common substrate. |
| FILED | Friday, May 17, 2019 |
| APPL NO | 17/055931 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Time-interval Measuring G04F 5/14 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11205535 | Levy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Jeremy Levy (Pittsburgh, Pennsylvania); Feng Bi (Pittsburgh, Pennsylvania); Patrick R. Irvin (Allison Park, Pennsylvania) |
| ABSTRACT | A structure includes an electronically controllable ferromagnetic oxide structure that includes at least three layers. The first layer comprises STO. The second layer has a thickness of at least about 3 unit cells, said thickness being in a direction substantially perpendicular to the interface between the first and second layers. The third layer is in contact with either the first layer or the second layer or both, and is capable of altering the charge carrier density at the interface between the first layer and the second layer. The interface between the first and second layers is capable of exhibiting electronically controlled ferromagnetism. |
| FILED | Wednesday, October 23, 2019 |
| APPL NO | 16/661908 |
| ART UNIT | 1785 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Static Stores G11C 11/155 (20130101) G11C 11/161 (20130101) G11C 11/1675 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/40 (20130101) H01F 10/06 (20130101) H01F 10/193 (20130101) H01F 10/3213 (20130101) H01F 13/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11205826 | Nagulu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Aravind Nagulu (New York, New York); Harish Krishnaswamy (New York, New York) |
| ABSTRACT | A circulator, comprising: a gyrator having a first side (1S) and a second side (2S) connected to a third port; a first transmission line section (TLS) having a 1 S connected to the 1 S of the gyrator and a 2S connected to a first port; a second TLS having a 1S connected to the first port and having a 2S connected to a second port; a third TLS having a 1S connected to the second port and having a 2S connected to the third port; a first cancellation path (CP) that is connected between the first port and the third port and introduces a current that is 90 degrees out of phase with a first voltage at the first port; and a second CP that is connected between the second port and the third port and introduces a current that is orthogonal to the current introduces by the first CP. |
| FILED | Tuesday, June 11, 2019 |
| APPL NO | 17/255679 |
| ART UNIT | 2843 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/38 (20130101) H01P 1/397 (20130101) Original (OR) Class Demodulation or Transference of Modulation From One Carrier to Another H03D 7/1458 (20130101) H03D 7/1466 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11205828 | Behdad et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Nader Behdad (Oregon, Wisconsin); John H. Booske (McFarland, Wisconsin); Hung Thanh Luyen (Madison, Wisconsin); Zongtang Zhang (Madison, Wisconsin) |
| ABSTRACT | A waveguide includes a first double-ridge waveguide, a second double-ridge waveguide, and a polarization rotator. The first double-ridge waveguide provides a phase of an input electrical field rotated 0° or 90°. The second double-ridge outputs an electric field with a polarization that is perpendicular to a first polarization of the input electrical field. The polarization rotator is mounted between the first double-ridge waveguide and the second double-ridge waveguide and includes a frame, a dielectric layer, a first conducting pattern layer forming a first conductor and a second conductor, a first switch connected between the first conductor and the second conductor, a second conducting pattern layer forming a third conductor and a fourth conductor, and a second switch connected between the third conductor and the fourth conductor. Wherein a phase rotation of 90° or −90° is provided by the polarization rotator based on a state of the first and second switch. |
| FILED | Tuesday, January 07, 2020 |
| APPL NO | 16/735846 |
| ART UNIT | 2843 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/165 (20130101) H01P 3/123 (20130101) Original (OR) Class Antennas, i.e Radio Aerials H01Q 1/50 (20130101) H01Q 21/0006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11205863 | Eiermann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Robert Eiermann (Ashland, Massachusetts); Richard J. Adams (Charlestown, Massachusetts) |
| ABSTRACT | An electrical nut assembly for coupling an electrical lug to an electrical post is disclosed. The electrical nut assembly comprises a compression fitting and a compression sleeve. The compression fitting comprises a material comprising a first yield strength and comprises an internal thread operable to electrically couple to the electrical post and a base surface configured to electrically couple to the electrical lug. The compression sleeve comprises a material comprising a second yield strength greater than the first yield strength and is sized to at least partially cover the compression fitting. The compression sleeve is configured to compress the compression fitting in a radial direction when fitted at least partially over the compression fitting and pressed or advanced axially towards the base surface and as the compression fitting makes contact with the electrical lug. |
| FILED | Tuesday, September 29, 2020 |
| APPL NO | 17/037184 |
| ART UNIT | 2833 — Electrical Circuits and Systems |
| CURRENT CPC | Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 4/34 (20130101) H01R 4/302 (20130101) Original (OR) Class H01R 4/305 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11205953 | Jacobson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| ASSIGNEE(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| INVENTOR(S) | Boris S. Jacobson (Westford, Massachusetts); Steven D. Bernstein (Brighton, Massachusetts); Steven M. Lardizabal (Westford, Massachusetts); Jason Adams (Medway, Massachusetts); Jeffrey R. Laroche (Austin, Texas) |
| ABSTRACT | A power converter assembly is provided and includes high quality factor (Q) shield-to-transistor integrated low-inductance capacitor elements to divert common mode (CM) currents, high Q shield-to-shield integrated low-inductance capacitor elements to compliment line-to-line filter capacitors and high Q baseplate integrated low-inductance capacitor elements to attenuate residual CM currents. |
| FILED | Monday, January 13, 2020 |
| APPL NO | 16/741318 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 27/36 (20130101) H01F 27/2804 (20130101) H01F 27/2885 (20130101) H01F 2027/2809 (20130101) H01F 2027/2819 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/005 (20200101) H02J 50/10 (20160201) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/44 (20130101) Original (OR) Class H02M 1/4258 (20130101) H02M 7/003 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/165 (20130101) H05K 2201/086 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11206276 | Nitz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Kenneth C. Nitz (Redwood City, California); Phillip Porras (Cupertino, California); Steven Cheung (San Francisco, California) |
| ABSTRACT | A correlator that includes a number of modules cooperating with each other. A transaction correlation module correlates network flow information for one or more network packet flows corresponding to one or more host-agent network-transaction records on whom participated in a network packet flow. The host-agent network-transaction records at least contain source information. A host input module to take in the host-agent network-transaction records from each host agent on its host computing device connecting to the correlator. A merged record creator creates a merged record for corresponding matches of one or more of the host-agent network-transaction records to one or more of the network packet flows. The merged record gives the network policy enforcement module a complete picture of both the network traffic flow information along with the source information that participated in the network packet flows in order to apply network polices against the network packet flows. |
| FILED | Monday, June 03, 2019 |
| APPL NO | 16/430185 |
| ART UNIT | 2435 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/20 (20130101) H04L 63/0236 (20130101) H04L 63/1425 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11206740 | Cole et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cree Fayetteville, Inc. (Fayetteville, Arkansas) |
| ASSIGNEE(S) | Cree Fayetteville, Inc. (Fayetteville, Arkansas) |
| INVENTOR(S) | Zachary Cole (Summers, Arkansas); Brandon Passmore (Fayetteville, Arkansas) |
| ABSTRACT | A power module includes a number of sub-modules connected via removable jumpers. The removable jumpers allow the connections between one or more power semiconductor die in the sub-modules to be reconfigured, such that when the removable jumpers are provided, the power module has a first function, and when the removable jumpers are removed, the power module has a second function. The removable jumpers may also allow for independent testing of the sub-modules. The power module may also include a multi-layer printed circuit board (PCB), which is used to connect one or more contacts of the power semiconductor die. The multi-layer PCB reduces stray inductance between the contacts and therefore improves the performance of the power module. |
| FILED | Thursday, July 23, 2020 |
| APPL NO | 16/936552 |
| ART UNIT | 2847 — Electrical Circuits and Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/4093 (20130101) H01L 23/5382 (20130101) H01L 25/072 (20130101) H01L 25/115 (20130101) H01L 25/162 (20130101) H01L 29/78 (20130101) H01L 29/1608 (20130101) H01L 2224/49111 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/088 (20130101) H02M 7/003 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0298 (20130101) H05K 5/0065 (20130101) Original (OR) Class H05K 5/0069 (20130101) H05K 2201/10166 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11202449 | Belfort et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York); HEALTH RESEARCH, INC. (Menands, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York); Health Research, Inc. (Menands, New York) |
| INVENTOR(S) | Georges Belfort (Albany, New York); C. Seth Pearson (Albany, New York); Brian Murray (Haverhill, Massachusetts); Pankaj Sakharam Karande (Troy, New York); Jun Ha Kwak (Troy, New York); Kathleen A. McDonough (Albany, New York); Zachary Andrew Kloos (New Haven, Connecticut) |
| ABSTRACT | Disclosed herein are novel anti-microbial peptides with inhibitory activity against M. tuberculosis and streptococcus bacteria. Additionally, a method for designing novel anti-microbial peptides is disclosed. |
| FILED | Tuesday, May 14, 2019 |
| APPL NO | 16/411652 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 43/38 (20130101) A01N 63/50 (20200101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/10 (20130101) A61K 45/06 (20130101) Peptides C07K 7/08 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11202759 | Huebsch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nathaniel D. Huebsch (Colma, California); Christopher M. Madl (Vestal, New York); Kangwon Lee (Lexington, Massachusetts); Maria M. Xu (Morgantown, West Virginia); David J. Mooney (Sudbury, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Nathaniel D. Huebsch (Colma, California); Christopher M. Madl (Vestal, New York); Kangwon Lee (Lexington, Massachusetts); Maria M. Xu (Morgantown, West Virginia); David J. Mooney (Sudbury, Massachusetts) |
| ABSTRACT | The invention provides compositions and methods to form pores in situ within hydrogels following hydrogel injection. Pores formed in situ via degradation of sacrificial porogens within the surrounding hydrogel facilitate recruitment or release of cells. Disclosed herein is a material that is not initially porous, but which becomes macroporous over time. |
| FILED | Thursday, October 06, 2011 |
| APPL NO | 13/877572 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1652 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/20 (20130101) A61L 27/20 (20130101) A61L 27/26 (20130101) A61L 27/38 (20130101) A61L 27/48 (20130101) A61L 27/48 (20130101) A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/58 (20130101) A61L 2300/414 (20130101) A61L 2400/06 (20130101) Compositions of Macromolecular Compounds C08L 5/04 (20130101) C08L 5/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11202823 | Scott et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Evan A. Scott (Northfield, Illinois); Chyung-Ru Wang (Evanston, Illinois); Shaobin Shang (Evanston, Illinois); Dina Kats (Evanston, Illinois) |
| ABSTRACT | Provided herein are subunit vaccine compositions comprising a nanocarrier and a lipid antigen, a peptide antigen or combinations thereof that elicit bother a CD1-restricted and an MHC-restricted T cell response in a subject. Methods for making and using the subunit vaccine compositions are also provided. |
| FILED | Friday, April 03, 2020 |
| APPL NO | 16/839861 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/51 (20130101) A61K 39/04 (20130101) Original (OR) Class A61K 2039/54 (20130101) A61K 2039/543 (20130101) A61K 2039/55588 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11202841 | Dragnea |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Indiana University (Bloomington, Indiana) |
| ASSIGNEE(S) | THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana) |
| INVENTOR(S) | Bogdan Dragnea (Bloomington, Indiana) |
| ABSTRACT | A multi-chromophore virus particle is constructed by covalent binding of chromophores and provides super-radiant behavior. A virus-enabled targeted vector is provided for imaging with qualitatively different optical emission properties from state-of-the-art agents. Bright emission is obtained through quantum coherence, which in turn is facilitated by the symmetry of the virus shell. In an exemplary embodiment the targeted vector is used in laser-guided surgery, specifically for the treatment of in brain cancer. |
| FILED | Tuesday, August 20, 2019 |
| APPL NO | 16/545301 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/20 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/0043 (20130101) A61K 49/0056 (20130101) A61K 49/0065 (20130101) A61K 49/0097 (20130101) Original (OR) Class A61K 49/1833 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 25/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203744 | Lynch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| INVENTOR(S) | Michael David Lynch (Durham, North Carolina); Zhixia Ye (Raleigh, North Carolina) |
| ABSTRACT | The present disclosure is related to genetically engineered microbial strains and related bioprocesses for the production of pyruvate and related products. Specifically, the use of dynamically controlled synthetic metabolic valves to reduce the activity of enzymes known to contribute to pyruvate synthesis, leads to increased pyruvate production in a two-stage process rather than a decrease in production. |
| FILED | Friday, June 21, 2019 |
| APPL NO | 16/448292 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) C12N 9/0036 (20130101) C12N 9/0051 (20130101) C12N 9/1025 (20130101) C12N 9/1205 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/40 (20130101) Enzymes C12Y 101/01049 (20130101) C12Y 106/03001 (20130101) C12Y 108/01004 (20130101) C12Y 203/03001 (20130101) C12Y 207/0104 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203765 | Song et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Wen-Yuan Song (Gainesville, Florida); Xiuhua Chen (St. Louis, Missouri); Xiaoen Huang (Gainesville, Florida) |
| ABSTRACT | Described are methods and compositions for enhancing drought tolerance in plants. Nucleic acid constructs therefore are also described. Transgenic plants are also provided that exhibit enhanced agronomic properties. The inventors have demonstrated increased drought tolerance in connection with increased expression of the Xa21 gene. |
| FILED | Monday, November 12, 2018 |
| APPL NO | 16/186954 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8237 (20130101) C12N 15/8273 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203770 | Angenent et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Largus T. Angenent (Tübingen, Germany); Leo Kucek (Lake Mills, Wisconsin) |
| ABSTRACT | Methods and systems to produce product compositions comprising caprylate products using chain-elongating bacteria. For example, the caprylate product in the product composition is n-caprylic acid (C8) and the n-caprylic (C8) to n-caproic (C6) acid ratio is higher than 1:1. These methods use chain elongation towards C8 rather than C6. High n-caprylate productivity and specificity was accomplished by: 1) feeding a substrate with, for example, ethanol as the carbon source or alternatively, a high ethanol-to-acetate ratio as the carbon source; 2) extracting caprylate product(s) (e.g., n-caprylate product) from the bioreactor broth; and 3) acclimating an efficient chain-elongating microbiome. The methods can produce caprylate products such as, for example, n-caprylic acid, which is a higher value chemical than C4 and C6. |
| FILED | Monday, January 06, 2020 |
| APPL NO | 16/735469 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/6409 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203773 | Shrader et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | Alanna Schepartz Shrader (New Haven, Connecticut); Wesley E. Robertson (New Haven, Connecticut); Clarissa Melo Czekster (St. Andrews, United Kingdom) |
| ABSTRACT | Engineered 23S rRNAs and methods of use thereof for translation of proteins incorporating non-standard amino acids are provided. Typically, the 23S rRNA includes one or more mutations at positions 2496-2507 relative to E. coli wildtype 23S rRNA, wherein a ribosome composed of the 23S rRNA can catalyze the covalent transfer of a non-standard amino acid from an aminoacyl-RNA onto a nascent peptide chain. For example, the 23S rRNA can include the sequence UGACUU at positions 2502-2507 relative to E. coli wildtype 23S rRNA, and optionally the sequence AGCGUGA from positions 2057-2063 relative to E. coli wildtype 23S rRNA. The 23S rRNA can include additional or alternative deletions, substitutions, insertions, or combination thereof. The compositions and methods can be used to make polypeptides and sequence defined polymers. |
| FILED | Friday, March 17, 2017 |
| APPL NO | 16/085927 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/104 (20130101) C12N 15/11 (20130101) C12N 15/67 (20130101) C12N 15/70 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Original (OR) Class Enzymes C12Y 203/02012 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203787 | Abate et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Adam R. Abate (Daly City, California); Dennis Jay Eastburn (Burlingame, California); Adam R. Sciambi (San Francisco, California) |
| ABSTRACT | Methods for the detection of components from biological samples are provided. In certain aspects, the methods may be used to detect and/or quantify specific components in a biological sample, such as tumor cells (e.g., circulating tumor cells). Systems and devices for practicing the subject methods are also provided. |
| FILED | Thursday, October 18, 2018 |
| APPL NO | 16/164707 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/0807 (20130101) B01F 5/0652 (20130101) B01F 13/0062 (20130101) B01F 13/0076 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502784 (20130101) B01L 7/52 (20130101) B01L 2200/0652 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2300/0883 (20130101) B01L 2300/1822 (20130101) B01L 2400/0415 (20130101) B01L 2400/0487 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/686 (20130101) C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6844 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2537/143 (20130101) C12Q 2563/159 (20130101) C12Q 2563/159 (20130101) C12Q 2565/629 (20130101) C12Q 2600/16 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203812 | Modestino et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | New York University (New York, New York) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Miguel A. Modestino (New York, New York); Yury Dvorkin (New York, New York); Daniel Frey (New York, New York); Daniela Eugenia Blanco Jimenez (Brooklyn, New York) |
| ABSTRACT | Provided are electrochemical cells for hydrogen production and methods for hydrogen production. The electrochemical cell and methods use a mediator that may have a reversible redox potential lying outside the onset of the oxygen evolution reaction (OER) and the hydrogen evolution reaction (HER). Also, provided are systems for generating hydrogen and water from oxygen and generating water from oxygen and hydrogen. |
| FILED | Monday, February 24, 2020 |
| APPL NO | 16/799454 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/02 (20130101) C25B 1/04 (20130101) Original (OR) Class C25B 9/19 (20210101) C25B 9/73 (20210101) C25B 15/08 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 16/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203817 | Acik et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Muge Acik (Lisle, Illinois); Seth B. Darling (Chicago, Illinois) |
| ABSTRACT | A method of forming lead halide perovskite crystals in a solvent. The perovskite is form by solution processing of an organic and inorganic precursor in a polar protic solvent. |
| FILED | Friday, June 30, 2017 |
| APPL NO | 15/640268 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/04 (20130101) Original (OR) Class C30B 7/14 (20130101) C30B 29/12 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/2059 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/005 (20130101) H01L 51/0007 (20130101) H01L 51/42 (20130101) H01L 51/5012 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11204251 | Schertz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Kathryn E. Schertz (Chicago, Illinois); Omid Kardan (Chicago, Illinois); Marc G. Berman (Chicago, Illinois); Thomas N. Kompare (Chicago, Illinois) |
| ABSTRACT | An embodiment may involve obtaining data representing a transportation map, a greenspace map, a noise map, and a crime map of a geographical location. The transportation map represents route segments within the geographical location, the greenspace map represents natural features within the geographical location, the noise map represents human-made noise within the geographical location, and the crime map represents reported crimes within the geographical location. The embodiment may also involve, for each of the route segments: (i) calculating a restorative score that is proportional to an amount of natural features associated with the respective route segment in the greenspace map, inversely proportional to an amount of human-made noise associated with the respective route segment in the noise map, and inversely proportional to an amount of crime associated with the respective route segment in the crime map. |
| FILED | Tuesday, May 21, 2019 |
| APPL NO | 16/418522 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/343 (20130101) Original (OR) Class G01C 21/3461 (20130101) G01C 21/3476 (20130101) G01C 21/3614 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11204838 | Mitsch et al. |
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| FUNDED BY |
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| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Stefan Mitsch (Pittsburgh, Pennsylvania); Andre Platzer (Pittsburgh, Pennsylvania) |
| ABSTRACT | Disclosed herein are techniques to make the synthesized monitoring conditions of partially-observable hybrid systems robust to partial observability of sensor uncertainty and partial controllability due to actuator disturbance. The approach herein shows that the monitoring conditions result in provable safety guarantees with fallback controllers that react to monitor violation at runtime. |
| FILED | Friday, November 15, 2019 |
| APPL NO | 16/685099 |
| ART UNIT | 2128 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 11/1415 (20130101) Original (OR) Class G06F 11/3409 (20130101) G06F 30/27 (20200101) G06F 2201/805 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11205097 | Masse et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | THE UNIVERSITY OF CHICAGO (Chicago, Illinois) |
| INVENTOR(S) | Nicolas Y. Masse (Chicago, Illinois); Gregory D. Grant (Chicago, Illinois); David J. Freedman (Chicago, Illinois) |
| ABSTRACT | A computing device may receive a first set of training data for training an ANN to predict output data for a first task, and may train the ANN with the first set of training data by only adjusting values of weights associated with a first subset of neurons, the first subset selected based on an identity of the first task. The computing device may receive a second, different set of training data for training the ANN to predict output data for a second task, and may train the ANN with the second set of training data by only adjusting values of weights associated with a second subset of neurons, the second subset selected based on an identity of the second task. During training, adjusting of the value of any weight may entail weight stabilization that depends on whether there has been any training for one or more previous tasks. |
| FILED | Tuesday, January 28, 2020 |
| APPL NO | 16/774343 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6228 (20130101) G06K 9/6257 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11205103 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University (Binghamton, New York) |
| INVENTOR(S) | Zhongfei Zhang (Vestal, New York); Shuangfei Zhai (Binghamton, New York) |
| ABSTRACT | A method of modelling data, comprising: training an objective function of a linear classifier, based on a set of labeled data, to derive a set of classifier weights; defining a posterior probability distribution on the set of classifier weights of the linear classifier; approximating a marginalized loss function for an autoencoder as a Bregman divergence, based on the posterior probability distribution on the set of classifier weights learned from the linear classifier; and classifying unlabeled data using the autoencoder according to the marginalized loss function. |
| FILED | Monday, December 11, 2017 |
| APPL NO | 15/838000 |
| ART UNIT | 2122 — AI & Simulation/Modeling |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6256 (20130101) G06K 9/6269 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/084 (20130101) G06N 3/0454 (20130101) G06N 3/0472 (20130101) G06N 7/005 (20130101) G06N 20/10 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11205139 | Woodbury |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Neal Woodbury (Tempe, Arizona) |
| ABSTRACT | Methods and systems, including those employing machine learning, utilizing one or more algorithms for relating the structure of a molecule in a library to its function are described. Embodiments described herein relate structure to function by considering the covalent structure of the molecule, the components of that structure that are common to many molecules in the library, and the properties of those components as they relate to the function in question. Applications include, for example, enhancement and amplification of the diagnostic and prognostic signals provided by peptide arrays for use in analyzing the profile of antibodies in the blood produced in response to a disease, condition or treatment. |
| FILED | Friday, August 02, 2019 |
| APPL NO | 16/637369 |
| ART UNIT | 2124 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 20/10 (20190101) Original (OR) Class Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11205535 | Levy et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Jeremy Levy (Pittsburgh, Pennsylvania); Feng Bi (Pittsburgh, Pennsylvania); Patrick R. Irvin (Allison Park, Pennsylvania) |
| ABSTRACT | A structure includes an electronically controllable ferromagnetic oxide structure that includes at least three layers. The first layer comprises STO. The second layer has a thickness of at least about 3 unit cells, said thickness being in a direction substantially perpendicular to the interface between the first and second layers. The third layer is in contact with either the first layer or the second layer or both, and is capable of altering the charge carrier density at the interface between the first layer and the second layer. The interface between the first and second layers is capable of exhibiting electronically controlled ferromagnetism. |
| FILED | Wednesday, October 23, 2019 |
| APPL NO | 16/661908 |
| ART UNIT | 1785 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Static Stores G11C 11/155 (20130101) G11C 11/161 (20130101) G11C 11/1675 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/40 (20130101) H01F 10/06 (20130101) H01F 10/193 (20130101) H01F 10/3213 (20130101) H01F 13/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11205565 | Belmont et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WYOMING (Laramie, Wyoming) |
| ASSIGNEE(S) | UNIVERSITY OF WYOMING (Laramie, Wyoming) |
| INVENTOR(S) | Erica Belmont (Laramie, Wyoming); Franco Basile (Ft. Collins, Colorado); James Rundel (Laramie, Wyoming); Andrew Goodenough (Laramie, Wyoming) |
| ABSTRACT | A method and apparatus for monitoring and/or controlling the extent of denaturation and/or bond cleavages of proteins on any surface (e.g., biological tissues, biofilms, etc.). In one embodiment, a low power laser (e.g., a 5 mW, 362 nm diode laser) is directed through a biological sample to a photodetector. The sample is heated by a set of radiant heaters to between about 220° C. and about 250° C. in a time period of between 10 seconds to 60 seconds. The baseline transmissivity of the sample is monitored continuously throughout treatment of the biological sample via continuous monitoring of the signal voltage detected at the photodetector. Upon detection of increase in relative transmissivity in the biological sample, the heating treatment is concluded and the biological sample is removed for in situ protein identification as part of an imaging MALDI-MS measurement. |
| FILED | Monday, July 29, 2019 |
| APPL NO | 16/524916 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/0004 (20130101) H01J 49/164 (20130101) H01J 49/0418 (20130101) Original (OR) Class H01J 49/0459 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11206146 | Thapliyal et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| ASSIGNEE(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| INVENTOR(S) | Himanshu Thapliyal (Lexington, Kentucky); Carson Labrado (Lexington, Kentucky) |
| ABSTRACT | An equivalent circuit architecture and attendant methods for generating a physically unclonable function (PUF) response include a plurality of devices capable of generating a voltage output, a voltage source, and a microcontroller adapted to receive the voltage output from each device of the plurality of devices. The devices may be energy harvesting devices or sensors. The microcontroller is configured to determine an average peak voltage for predefined groups of the plurality of devices, to compare summation voltage values for the predefined groups, and from that information to output response values defining a 128-bit PUF response. The microcontroller determines a peak voltage of each device of the plurality of devices an equal number of times to generate the 128 bit PUF response value, this preventing biasing the response towards any individual device or group of devices. |
| FILED | Monday, August 03, 2020 |
| APPL NO | 16/983329 |
| ART UNIT | 2491 — Cryptography and Security |
| CURRENT CPC | Information and Communication Technology Specially Adapted for the Internet of Things [IOT] G16Y 30/10 (20200101) Electric Machines Not Otherwise Provided for H02N 2/181 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3278 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11203013 | Davis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California); William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California); William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Mark E. Davis (Pasadena, California); Stephen Kramer Brand (Pasadena, California); Joel E. Schmidt (Utrecht, Netherlands); Michael W. Deem (West University Place, Texas) |
| ABSTRACT | This disclosure describes enantiomerically enriched chiral molecular sieves and methods of making and using the same. In some embodiments, the molecular sieves are silicates or germanosilicates of STW topology. |
| FILED | Friday, January 19, 2018 |
| APPL NO | 15/875245 |
| ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 29/047 (20130101) Original (OR) Class B01J 31/0244 (20130101) B01J 35/002 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/07 (20130101) Acyclic or Carbocyclic Compounds C07C 2529/04 (20130101) Heterocyclic Compounds C07D 233/66 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/20075 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/46 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203553 | Gomez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| ASSIGNEE(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| INVENTOR(S) | Enrique Gomez (University Park, Pennsylvania); Wonho Lee (University Park, Pennsylvania) |
| ABSTRACT | Highly dense lithium based ceramics can be prepared by a low temperature process including combining a lithium based ceramic with a polar solvent having a lithium based salt dissolved therein and applying pressure and heat to the combination to form a salt-ceramic composite. Advantageously, the lithium salt is one that dissolves in the polar solvent and the heat applied to the combination is no greater than about 250° C. Such composites can also have high ionic conductivity. |
| FILED | Friday, April 05, 2019 |
| APPL NO | 16/376538 |
| ART UNIT | 1759 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/515 (20130101) Original (OR) Class C04B 35/6264 (20130101) C04B 2235/447 (20130101) C04B 2235/604 (20130101) C04B 2235/608 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/052 (20130101) H01M 10/056 (20130101) H01M 2300/0091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203702 | Whiting et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Joshua J. Whiting (Albuquerque, New Mexico); David R. Wheeler (Albuquerque, New Mexico); Robert J. Simonson (Cedar Crest, New Mexico); Douglas Read (Bosque Farms, New Mexico); Leah Appelhans (Tijeras, New Mexico) |
| ABSTRACT | The present invention relates to functionalized polymers useful for coating surfaces, such as the internal bore of a column. In particular embodiments, such functionalized polymers provide a selective stationary phase useful for separating and detecting organophosphorous agents. Methods of using such polymers are also described herein. |
| FILED | Thursday, October 17, 2019 |
| APPL NO | 16/656228 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 7/22 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/23 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 7/63 (20180101) C09D 183/06 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/56 (20130101) G01N 2030/025 (20130101) G01N 2030/143 (20130101) G01N 2030/567 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203746 | Morant et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Novozymes, Inc. (Davis, California) |
| ASSIGNEE(S) | Novozymes, Inc. (Davis, California) |
| INVENTOR(S) | Marc D. Morant (Bagsvaerd, Denmark); Paul Harris (Carnation, Washington) |
| ABSTRACT | The present invention relates to isolated polypeptides having cellobiohydrolase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. |
| FILED | Thursday, December 06, 2018 |
| APPL NO | 16/211604 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2437 (20130101) Original (OR) Class C12N 9/2445 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/14 (20130101) C12P 19/02 (20130101) C12P 19/14 (20130101) C12P 21/00 (20130101) C12P 2201/00 (20130101) Enzymes C12Y 302/01004 (20130101) C12Y 302/01091 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203759 | Kiley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Patricia J. Kiley (Middleton, Wisconsin); Dan M. Park (Dublin, California) |
| ABSTRACT | The invention provided herein relates to sequence determinants that elicit certain levels of gene expression and methods for obtaining engineered ligand-responsive gene switches comprising these sequence determinants. More particularly, the invention provided herein relates to molecular building blocks (i.e., discrete nucleotide sequences), synthetic ligand-responsive gene switches comprising an assembly of these molecular building blocks, and methods of using synthetic ligand-responsive gene switches as customizable and controllable expression systems and sensors. |
| FILED | Thursday, September 07, 2017 |
| APPL NO | 15/698302 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) C12N 15/70 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203817 | Acik et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Muge Acik (Lisle, Illinois); Seth B. Darling (Chicago, Illinois) |
| ABSTRACT | A method of forming lead halide perovskite crystals in a solvent. The perovskite is form by solution processing of an organic and inorganic precursor in a polar protic solvent. |
| FILED | Friday, June 30, 2017 |
| APPL NO | 15/640268 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/04 (20130101) Original (OR) Class C30B 7/14 (20130101) C30B 29/12 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/2059 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/005 (20130101) H01L 51/0007 (20130101) H01L 51/42 (20130101) H01L 51/5012 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203947 | Croteau et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Paul F. Croteau (Columbia, Connecticut); John E. Holowczak (Windsor, Connecticut); Thomas J. Martin (East Hampton, Connecticut); Paul Attridge (Colchester, Connecticut) |
| ABSTRACT | An airfoil includes an airfoil section that has an airfoil wall that surrounds a cavity. The airfoil wall includes a first wall section comprised of a monolithic ceramic shell, a second wall section comprised of a CMC liner that is bonded along an interface to an interior side of the monolithic ceramic shell, and a ceramic barrier coating that is bonded to an exterior side of the monolithic ceramic shell. The airfoil wall includes at least one of: inter-section cooling channels that extend along the interface and are bounded by the monolithic ceramic shell and the CMC liner, or intra-section cooling channels that extend within the CMC liner. |
| FILED | Friday, May 08, 2020 |
| APPL NO | 16/870310 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/02 (20130101) F01D 9/065 (20130101) Original (OR) Class F01D 25/12 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/12 (20130101) F05D 2300/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11204321 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Hanyu Zhang (Indianapolis, Indiana); Elisa M. Link (Denver, Colorado) |
| ABSTRACT | The present disclosure relates to a device that includes a light source, a detector; and a film having a first surface that includes a transition metal dichalcogenide, where the film is configured to interact with a volume of gas containing a concentration of water vapor, the light source is configured to shine a first light onto the first surface, the film is configured, as a result of the first light, to emit from the first surface a second light, the detector is configured to receive at least a portion of the second light, and the detector is configured to generate a signal proportional to an intensity of the second light. |
| FILED | Monday, August 24, 2020 |
| APPL NO | 17/000469 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/56 (20130101) C23C 16/305 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/64 (20130101) Original (OR) Class G01N 2201/062 (20130101) G01N 2201/06113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11204444 | Bahritdinov |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Farhod Bahritdinov (Amarillo, Texas) |
| ABSTRACT | A quantum dot (QD) lightning detection and warning (LDW) system and method. This LDW system and method find broader applicability to spark and other transient optical event detection as well. The QDs are operable for receiving ultraviolet (UV), infrared (IR), visible, x-ray, and/or gamma ray radiation emanating from lightning or the like and generating visible radiation that may be detected and utilized to generate topological event information, such that property, human life, and the like may be safeguarded. |
| FILED | Monday, October 01, 2018 |
| APPL NO | 16/147981 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/781 (20130101) G01S 3/7806 (20130101) G01S 5/16 (20130101) G01S 5/166 (20130101) Meteorology G01W 1/16 (20130101) Original (OR) Class Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11205530 | Watson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Scott Avery Watson (Jemez Springs, New Mexico); Nicola Maree Winch (Los Alamos, New Mexico); Eric Byron Sorensen (Los Alamos, New Mexico); Lawrence Eugene Bronisz (Los Alamos, New Mexico); David Platts (Los Alamos, New Mexico); Michael L. Krogh (Los Alamos, New Mexico); Marcelo Norona (Los Alamos, New Mexico); Phillip A. Duran (Los Alamos, New Mexico) |
| ABSTRACT | A process for constructing a high-tensile strength, high-gradient insulator (HGI) may include stacking alternating layers of conductors and insulators, and vacuum pressure potting the stacked layers onto an insulating rod. The process may also include post machining the stacked layers to form a complete assembly of the HGI. |
| FILED | Tuesday, December 11, 2018 |
| APPL NO | 16/217021 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 17/28 (20130101) H01B 17/64 (20130101) H01B 17/66 (20130101) H01B 19/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11205734 | France et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); California Institute of Technology (Pasedena, California) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Ryan Matthew France (Golden, Colorado); John Franz Geisz (Wheat Ridge, Colorado); Pilar Espinet-Gonzalez (Pasadena, California) |
| ABSTRACT | Distributed Bragg reflectors are incorporated into the compositionally graded buffers of metamorphic solar cells, adding functionality to the buffer without adding cost. The reflection aids in collection in subcells that are optically thin due to low diffusion length, high bulk recombination, radiation hardness, partially-absorbing quantum structures, or simply for cost savings. Performance enhancements are demonstrated in GaAs subcells with QWs, which is beneficial when GaAs is not the ideal bandgap. |
| FILED | Friday, February 22, 2019 |
| APPL NO | 16/283375 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0547 (20141201) H01L 31/03046 (20130101) H01L 31/06875 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11205778 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gao Liu (Piedmont, California); Tianyue Zheng (Albany, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Gao Liu (Piedmont, California); Tianyue Zheng (Albany, California) |
| ABSTRACT | The present invention provides for an emulsion comprising solid particles of a single composition, or a mixture thereof, comprising a polymer comprising one monomer of an aryl methacrylate, or a mixture thereof, co-polymerized with a monomer of an alkyl methacrylate, or a mixture thereof; wherein Ar is an aryl group and R is an alkyl group, and n:m has a ratio of from about 0:100 to about 100:0. |
| FILED | Friday, June 12, 2020 |
| APPL NO | 16/900556 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/1804 (20200201) C08F 220/1818 (20200201) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/07 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/20 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/386 (20130101) H01M 4/387 (20130101) H01M 4/622 (20130101) Original (OR) Class H01M 4/625 (20130101) H01M 10/0525 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11205795 | Surendranath et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | FuelCell Energy, Inc. (Danbury, Connecticut) |
| ASSIGNEE(S) | FuelCell Energy, Inc. (Danbury, Connecticut) |
| INVENTOR(S) | Arun Surendranath (Danbury, Connecticut); Abdelkader Hilmi (Bethel, Connecticut); Chao-Yi Yuh (New Milford, Connecticut) |
| ABSTRACT | A reinforced electrolyte matrix for a molten carbonate fuel cell includes a porous ceramic matrix, a molten carbonate salt provided in the porous ceramic matrix, and at least one reinforcing structure comprised of at least one of yttrium, zirconium, cerium or oxides thereof. The reinforcing structure does not react with the molten carbonate salt. The reinforced electrolyte matrix separates a porous anode and a porous cathode in the molten carbonate fuel cell. |
| FILED | Monday, November 21, 2016 |
| APPL NO | 15/357607 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/905 (20130101) H01M 4/8605 (20130101) H01M 4/9033 (20130101) H01M 8/142 (20130101) H01M 8/145 (20130101) Original (OR) Class H01M 8/0295 (20130101) H01M 2008/147 (20130101) H01M 2300/0051 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/50 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/50 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11205972 | Post |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Richard F. Post (Walnut Creek, California) |
| ABSTRACT | A mechanical system is provided for maintaining a desired gap between a stator electrode array and a rotor electrode array by employing repelling magnets on the inner surface of the rotor and on movable carts that support azimuthally segmented stator arrays. |
| FILED | Thursday, March 28, 2019 |
| APPL NO | 16/368478 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Machines Not Otherwise Provided for H02N 1/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11206278 | Veeramany et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Arun Veeramany (Richland, Washington); William James Hutton, III (Benton City, Washington); Siddharth Sridhar (Seattle, Washington); Sri Nikhil Gupta Gourisetti (Richland, Washington); Garill A. Coles (Richland, Washington); Mark J. Rice (Richland, Washington); Paul M. Skare (Richland, Washington); David O. Manz (Pasco, Washington); Jeffery E. Dagle (Richland, Washington); Stephen D. Unwin (Richland, Washington) |
| ABSTRACT | Technology related to risk-informed autonomous adaptive cyber controllers is disclosed. In one example of the disclosed technology, a method includes generating probabilities of a cyber-attack occurring along an attack surface of a network. The probabilities can be generated using sensor and operational data of a network as inputs to an attack graph. The risk scores can be determined using a plurality of fault trees and the generated probabilities from the attack graph. The respective risk scores can correspond to respective nodes of an event tree. The event tree and the determined risk scores can be used to determine risk estimates for a plurality of configurations of the network. The risk estimates for the plurality of configurations of the network can be used to reconfigure the network to reduce a risk from the cyber-attack. |
| FILED | Wednesday, June 05, 2019 |
| APPL NO | 16/432655 |
| ART UNIT | 2434 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/16 (20130101) H04L 41/142 (20130101) H04L 63/20 (20130101) H04L 63/0236 (20130101) H04L 63/1416 (20130101) H04L 63/1433 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11206287 | Pal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Seemita Pal (Richland, Washington); Arun Veeramany (Richland, Washington); Christopher A. Bonebrake (West Richland, Washington); Beverly E. Johnson (Richland, Washington); William James Hutton, III (Benton City, Washington); Siddharth Sridhar (Seattle, Washington); Sri Nikhil Gupta Gourisetti (Richland, Washington); Garill A. Coles (Richland, Washington) |
| ABSTRACT | Technology related to evaluating cyber-risk for synchrophasor systems is disclosed. In one example of the disclosed technology, a method includes generating an event tree model of a timing-attack on a synchrophasor system architecture. The event tree model can be based on locations and types of timing-attacks, an attack likelihood, vulnerabilities and detectability along a scenario path, and consequences of the timing-attack. A cyber-risk score of the synchrophasor system architecture can be determined using the event tree model. The synchrophasor system architecture can be adapted in response to the cyber-risk score. |
| FILED | Tuesday, January 29, 2019 |
| APPL NO | 16/261283 |
| ART UNIT | 2494 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1433 (20130101) H04L 63/1466 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11202419 | Goodstal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arcadia Biosciences, Inc. (Davis, California) |
| ASSIGNEE(S) | ARCADIA BIOSCIENCES, INC. (Phoenix, Arizona) |
| INVENTOR(S) | Floyd John Goodstal (Davis, California); Daniel Facciotti (Davis, California) |
| ABSTRACT | Soybean plants with one or more non-transgenic human-induced mutations of the phytate transport genes, LPA-3 and LPA-19, and the agglutinin gene, LEC1, are disclosed. Soybean plants and seeds having reduced levels of phytate and/or lectin as a result of such non-transgenic human-induced mutations are provided. Meal prepared from soybean seeds provided herein is useful, for example, as a source of food or feed for poultry, human, swine, or fish, wherein the food or feed has reduced levels of antinutrient factors, including phytate and lectin. |
| FILED | Thursday, March 12, 2020 |
| APPL NO | 16/816751 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 1/06 (20130101) Original (OR) Class A01H 5/10 (20130101) A01H 6/542 (20180501) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8218 (20130101) C12N 15/8251 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203618 | Joens et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Lynn A. Joens (Tucson, Arizona); Bibiana Law (Tucson, Arizona); Alexandra Armstrong (Tucson, Arizona) |
| ABSTRACT | The present disclosure provides immunogenic compositions against Campylobacter and methods for using the immunogenic composition to generate an immune response against Campylobacter and/or reduce intestinal colonization by Campylobacter. |
| FILED | Friday, June 05, 2020 |
| APPL NO | 16/893667 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/105 (20130101) A61K 2039/53 (20130101) A61K 2039/522 (20130101) A61K 2039/523 (20130101) Peptides C07K 14/205 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/74 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11203765 | Song et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Wen-Yuan Song (Gainesville, Florida); Xiuhua Chen (St. Louis, Missouri); Xiaoen Huang (Gainesville, Florida) |
| ABSTRACT | Described are methods and compositions for enhancing drought tolerance in plants. Nucleic acid constructs therefore are also described. Transgenic plants are also provided that exhibit enhanced agronomic properties. The inventors have demonstrated increased drought tolerance in connection with increased expression of the Xa21 gene. |
| FILED | Monday, November 12, 2018 |
| APPL NO | 16/186954 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8237 (20130101) C12N 15/8273 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11204274 | Moore et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | Andrew J. Moore (Williamsburg, Virginia); Nicholas H. Rymer (Hampton, Virginia); Matthew R. Schubert (Newport News, Virginia) |
| ABSTRACT | Systems, methods, and devices of the various embodiments may enable the detection and localization of power line corona discharges and/or electrical arcs by an unmanned aerial vehicle (UAV) including an ultraviolet (UV) sensor and a reflective parabolic dish. In various embodiments, the UV sensor may use the photoelectric effect to sense narrow-band UV photons in a Geiger-Mueller tube and circuit configuration. In various embodiments, the reflective parabolic dish may be fixed relative to the UV sensor and include a reflective concave surface. The reflective concave surface may be configured to reflect narrow-band UV photons toward the UV sensor. |
| FILED | Monday, October 15, 2018 |
| APPL NO | 16/159907 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/12 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/0219 (20130101) G01J 1/0411 (20130101) G01J 1/429 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 31/1218 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 47/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11204334 | Kutscha et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Eileen O. Kutscha (Seattle, Washington); Tyler J. Zimmerman (Edmonds, Washington); Richard A. Miller, II (Seattle, Washington); Kay Y. Blohowiak (Issaquah, Washington) |
| ABSTRACT | There is provided a method for determining a quality of an abrasive surface preparation of a composite surface, prior to the composite surface undergoing a post-processing operation. The method includes fabricating levels of abrasive surface preparation standards for a reference composite surface; using a surface analysis tool in the form of an ohm meter, to create target values for quantifying the levels; and measuring, with the surface analysis tool, one or more abrasive surface preparation locations on the composite surface of a test composite structure, to measure one or more of, electrical resistance and surface resistivity, of the composite surface, to obtain test result measurement(s). The method further includes comparing the test result measurement(s) to the levels, to obtain test result level(s); determining if the test result level(s) meet the target value(s); and determining whether the composite surface is acceptable to proceed with the post-processing operation. |
| FILED | Monday, August 19, 2019 |
| APPL NO | 16/544859 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 7/12 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/20 (20130101) Original (OR) Class G01N 27/041 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 27/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11205987 | Biglari et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Geocent, LLC (Metarie, Louisiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Haik Biglari (Huntsville, Alabama); David Young (Madison, Alabama); Nicolas Mateo (Huntsville, Alabama); Matthew Owney (Merritt Island, Florida) |
| ABSTRACT | A specialized variable speed drive of the present invention is capable of controlling a motor and increasing the efficiency of both an ACIM or DCBL motor by biasing operation in favor of a class AB mode. The variable speed drive may be configured with two gate drivers where one gate driver is a class D gate driver and the second gate driver is either a class AB gate driver or a class C gate driver. The system also operates to reduce electro-magnetic interference in the operation of motors while increasing the reliability of the overall VSD system. |
| FILED | Monday, January 13, 2020 |
| APPL NO | 16/741387 |
| ART UNIT | 2846 — Electrical Circuits and Systems |
| CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 10/08 (20130101) Positive-displacement Machines for Liquids; Pumps F04B 49/065 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 7/5395 (20130101) Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 27/14 (20130101) H02P 27/085 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 11204288 | Tew, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
| INVENTOR(S) | Weston Leo Tew, Jr. (Clarksburg, Maryland); Jay Robert Nanninga (Monrovia, Maryland) |
| ABSTRACT | A triple point immersion cell article determines a triple point of a non-metallic analyte and includes: a first cryochamber including a first cryo-zone; a second cryochamber including a second cryo-zone that is: nested and disposed in the first cryochamber; and thermally isolated by the first cryochamber; a third cryochamber including a third cryo-zone, the third cryochamber being: nested and disposed in the second cryochamber; thermally isolated from the exterior environment by the first cryochamber and the second cryochamber; and thermally isolated from the first cryochamber by the second cryochamber; and a fourth cryochamber including a fourth cryo-zone disposed in the third cryochamber; a triple-point pressure vessel disposed in the fourth cryochamber; and a thermowell disposed in the triple-point pressure vessel. |
| FILED | Wednesday, September 11, 2019 |
| APPL NO | 16/567765 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 1/02 (20130101) G01K 1/08 (20130101) G01K 11/06 (20130101) G01K 13/006 (20130101) Original (OR) Class G01K 2203/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 11206544 | Boyd et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Apple Inc. (Cupertino, California) |
| ASSIGNEE(S) | Apple Inc. (Cupertino, California) |
| INVENTOR(S) | Daniel A. Boyd (Arlington, Virginia); Kelli L. Biegger (McLean, Virginia); Chang Ellison (Arlington, Virginia); Brandon P. Gutierrez (Burke, Virginia); Jason Lim (Alexandria, Virginia); Ho Cheung Chung (Sunnyvale, California); Irene M. Graff (Cupertino, California); Martijn Theo Haring (Utrecht, Netherlands); Ahmer A. Khan (San Jose, California); Franck Farian Rakotomalala (Dublin, California) |
| ABSTRACT | An embodiment includes a method to increase the efficiency of security checkpoint operations. A security checkpoint kiosk serves as a Relying Party System (RPS). The RPS establishes a secure local connection between the RPS and a User Mobile-Identification-Credential Device (UMD). The RPS sends a user information request to the UMD, via the secure local connection, seeking release of user information associated with a Mobile Identification Credential (MIC). The RPS obtains authentication of the user information received in response to the user information request. The RPS retrieves user travel information based on the user information. The RPS determines that the user travel information matches the user information. When the user travel information matches the user information, the RPS approves the user to proceed past the security checkpoint kiosk. |
| FILED | Friday, February 19, 2021 |
| APPL NO | 17/180509 |
| ART UNIT | 2493 — Cryptography and Security |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/265 (20130101) Wireless Communication Networks H04W 4/80 (20180201) H04W 12/02 (20130101) H04W 12/037 (20210101) H04W 12/47 (20210101) H04W 12/69 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11202419 | Goodstal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arcadia Biosciences, Inc. (Davis, California) |
| ASSIGNEE(S) | ARCADIA BIOSCIENCES, INC. (Phoenix, Arizona) |
| INVENTOR(S) | Floyd John Goodstal (Davis, California); Daniel Facciotti (Davis, California) |
| ABSTRACT | Soybean plants with one or more non-transgenic human-induced mutations of the phytate transport genes, LPA-3 and LPA-19, and the agglutinin gene, LEC1, are disclosed. Soybean plants and seeds having reduced levels of phytate and/or lectin as a result of such non-transgenic human-induced mutations are provided. Meal prepared from soybean seeds provided herein is useful, for example, as a source of food or feed for poultry, human, swine, or fish, wherein the food or feed has reduced levels of antinutrient factors, including phytate and lectin. |
| FILED | Thursday, March 12, 2020 |
| APPL NO | 16/816751 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 1/06 (20130101) Original (OR) Class A01H 5/10 (20130101) A01H 6/542 (20180501) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8218 (20130101) C12N 15/8251 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 11203619 | Gruver et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PIONEER HI-BRED INTERNATIONAL, INC. (Johnston, Iowa) |
| ASSIGNEE(S) | PIONEER HI-BRED INTERNATIONAL, INC. (, None) |
| INVENTOR(S) | Steven D Gruver (Pacifica, California); Heather Kozy (Walnut Creek, California); Jessica O'Rear (Redwood City, California); Barbara Rosen (Mountain View, California); Ute Schellenberger (Palo Alto, California); Jun-Zhi Wei (Hayward, California); Weiping Xie (East Palo Alto, California); Xiaohong Zhong (San Leandro, California); Genhai Zhu (San Jose, California) |
| ABSTRACT | Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity. |
| FILED | Monday, September 28, 2020 |
| APPL NO | 17/034019 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/46 (20130101) A01N 63/27 (20200101) A01N 63/50 (20200101) A01N 63/50 (20200101) Peptides C07K 14/21 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8286 (20130101) Technologies for Adaptation to Climate Change Y02A 40/146 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, December 21, 2021.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2021/details-patents-20210427.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page