FedInvent™ Patents

Patent Details for Tuesday, December 28, 2021 

This page was updated on Thursday, December 30, 2021 at 11:15 PM GMT

Department of Health and Human Services (HHS) 

US 11206976 Smith
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) New York University (New York, New York)
ASSIGNEE(S) NEW YORK UNIVERSITY (New York, New York)
INVENTOR(S) R. Theodore Smith (New York, New York)
ABSTRACT A system and method are for analyzing fluorescence of fluorophors in an eye using a non-negative matrix factorization (NMF) method. The NMF method may be initialized with Gaussian mixture model fits and may optionally be constrained to provide identical abundance images for data obtained in response to two or more excitation wavelengths.
FILED Thursday, October 15, 2015
APPL NO 14/884445
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 3/10 (20130101)
A61B 3/12 (20130101)
A61B 3/14 (20130101)
A61B 3/0025 (20130101) Original (OR) Class
A61B 3/1025 (20130101)

Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/4406 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6486 (20130101)
G01N 2021/6417 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 40/10 (20190201)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 30/00 (20180101)
G16H 50/20 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207010 Simon
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Anthony J. Simon (Davis, California)
ABSTRACT The disclosed embodiments relate to a system that uses a video game to improve spatial and/or temporal information-processing capabilities of a user. During operation, the system enables the user to play the video game. During execution of the video game, the system first measures spatial and/or temporal information-processing capabilities of the user during the course of playing the video game. Next, the system uses the measured spatial and/or temporal information-processing capabilities to control a spatial placement and/or a temporal presentation rate of target items that the user is required to respond to during subsequent game play to stimulate enhancement of the user's spatial and/or temporal information-processing capabilities.
FILED Wednesday, September 04, 2019
APPL NO 16/560651
ART UNIT 3715 — Amusement and Education Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/162 (20130101) Original (OR) Class
A61B 5/168 (20130101)
A61B 5/4836 (20130101)
A61B 5/7475 (20130101)

Card, Board, or Roulette Games; Indoor Games Using Small Moving Playing Bodies; Video Games; Games Not Otherwise Provided for
A63F 13/44 (20140902)
A63F 13/67 (20140902)
A63F 2300/64 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207028 Shusterman
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Vladimir Shusterman (Pittsburgh, Pennsylvania)
ASSIGNEE(S)
INVENTOR(S) Vladimir Shusterman (Pittsburgh, Pennsylvania)
ABSTRACT A system and method adapted for at least one health-related application selected from physiological monitoring, defibrillation, and pacing in the presence of electromagnetic interference (EMI) using the time-domain features of EMI patterns and physiological waveforms. The invention enables EMI detection and identification in a plurality of signals, including various physiological signals, which may contain both physiological information and EMI-generated artifacts. The system utilizes adaptive and versatile modular architecture with a set of modules for various filtering, conditioning, processing, and wireless transmission functions, which can be assembled in different configurations for different settings. In some preferred embodiments, the method and system of this invention are incorporated into (or attached to) an external cardiac defibrillator/monitor or cardiac pacing device. Other preferred embodiments include a wireless monitoring system that provides reliable wireless data transmission during patient table (bed) movement.
FILED Monday, January 28, 2019
APPL NO 16/260098
ART UNIT 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0002 (20130101)
A61B 5/002 (20130101)
A61B 5/0006 (20130101)
A61B 5/021 (20130101)
A61B 5/0024 (20130101)
A61B 5/053 (20130101)
A61B 5/055 (20130101)
A61B 5/0205 (20130101)
A61B 5/0263 (20130101)
A61B 5/0285 (20130101)
A61B 5/0295 (20130101)
A61B 5/318 (20210101)
A61B 5/369 (20210101)
A61B 5/389 (20210101)
A61B 5/02152 (20130101)
A61B 5/02433 (20130101)
A61B 5/7203 (20130101) Original (OR) Class
A61B 5/7217 (20130101)
A61B 5/7225 (20130101)
A61B 5/7282 (20130101)
A61B 5/14551 (20130101)
A61B 5/14552 (20130101)
A61B 7/04 (20130101)
A61B 2562/0219 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/3718 (20130101)
A61N 1/3925 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/42 (20130101)
G01R 33/5673 (20130101)

Transmission Systems for Measured Values, Control or Similar Signals
G08C 17/02 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 40/63 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207053 Walton
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) UNIVERSITY OF HAWAII (Honolulu, Hawaii)
ASSIGNEE(S) UNIVERSITY OF HAWAII (Honolulu, Hawaii)
INVENTOR(S) Chad Walton (Honolulu, Hawaii)
ABSTRACT The present disclosure generally relates to using high frequency ultrasound to assess blood volume changes in a subject. A baseline blood volume value can be determined based on a weight of a subject or based on an initial/previous assessment test value. An image taken with the high frequency ultrasound can be retrieved. A test blood volume value can be measured in a field of view of the image. For example, the test blood volume can be determined based on a destruction/replenishment of a contrast agent during imaging by the high frequency ultrasound. A change in blood volume in the subject can be estimated by comparing the test blood volume value to the baseline blood volume value. The estimate of the change in blood volume can be used to assess a condition of the subject.
FILED Wednesday, August 31, 2016
APPL NO 15/765295
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 8/06 (20130101)
A61B 8/481 (20130101) Original (OR) Class
A61B 8/488 (20130101)
A61B 8/0883 (20130101)
A61B 8/0891 (20130101)
A61B 8/4488 (20130101)
A61B 8/5223 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207277 Gudas et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Cornell University (Ithaca, New York)
ASSIGNEE(S) CORNELL UNIVERISITY (Ithaca, New York)
INVENTOR(S) Lorraine J Gudas (New York, New York);  Yannick Benoit (Ontario, Canada);  Ronald Perez (Somerset, New Jersey);  Xiao-Han Tang (Staten Island, New York);  Steven Trasino (Brooklyn, New York)
ABSTRACT This invention relates to pharmaceutical composition and methods of using vitamin A and/or RARβ agonist for the treatment or prevention of diseases or conditions associated with high fat diet and/or vitamin deficiency.
FILED Friday, November 08, 2019
APPL NO 16/677780
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/07 (20130101) Original (OR) Class
A61K 31/192 (20130101)
A61K 31/203 (20130101)
A61K 31/426 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207283 Silverman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois);  The University of Chicago (Chicago, Illinois)
INVENTOR(S) Richard B. Silverman (Winnetka, Illinois);  Hoang V. Le (Oxford, Mississippi);  Rima L. McLeod (Chicago, Illinois);  Dustin D. Hawker (Evanston, Illinois)
ABSTRACT Disclosed are methods, compounds, and compositions for treating infection by an Apicomplexan parasite that include administering a compound that selectively inactivates ornithine aminotransferase of the Apicomplexan parasite. Specifically, the methods, compounds, compounds may be utilized for treating infection by Toxoplasma gondii and toxoplasmosis and for treating infection by Plasmodium falciparum and malaria. The compounds disclosed herein are observed to selectively inactivate Toxoplasma gondii ornithine aminotransferase (TgOAT) relative to human OAT and relative to human γ-aminobutyric aminotransferase (GABA-AT).
FILED Tuesday, March 31, 2020
APPL NO 16/836870
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/03 (20130101)
A61K 31/13 (20130101)
A61K 31/035 (20130101)
A61K 31/40 (20130101)
A61K 31/196 (20130101) Original (OR) Class
A61K 31/341 (20130101)
A61K 31/381 (20130101)

Acyclic or Carbocyclic Compounds
C07C 229/34 (20130101)
C07C 229/38 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1096 (20130101)

Enzymes
C12Y 206/01013 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207296 Turchi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Cancer Institute (NCI)
APPLICANT(S) INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (Indianapolis, Indiana)
ASSIGNEE(S) Indiana University Research and Technology Corporation (Indianapolis, Indiana)
INVENTOR(S) John J. Turchi (Indianapolis, Indiana);  Navnath Gavande (Indianapolis, Indiana);  Pamela S. Vandervere-Carozza (Zionsville, Indiana)
ABSTRACT The present disclosure relates to certain compounds having binding affinity for XPA, and uses thereof. Specifically, the present disclosure relates to the use of XPA inhibitors as described herein in in methods of treating cancer.
FILED Tuesday, September 18, 2018
APPL NO 16/647746
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/4155 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207315 Tang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida);  THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland);  The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) Florida State University Research Foundation, Inc. (Tallahassee, Florida);  The Johns Hopkins University (Baltimore, Maryland);  The United States of America, as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Hengli Tang (Tallahassee, Florida);  Emily M. Lee (Tallahassee, Florida);  Anil Mathew Tharappel (Tallahassee, Florida);  Hongjun Song (Baltimore, Maryland);  Guo-Li Ming (Baltimore, Maryland);  Wei Zheng (Rockville, Maryland);  Miao Xu (Rockville, Maryland);  Shu Yang (Rockville, Maryland);  Ruili Huang (Rockville, Maryland);  Wenwei Huang (Rockville, Maryland);  Khalida Shamim (Gaithersburg, Maryland);  Hao Li (Rockville, Maryland)
ABSTRACT The present invention concerns the use of emetine compounds for the treatment or prevention of Flavivirus infections, such as dengue virus infections. Aspects of the invention include methods for treating or preventing Flavivirus virus infection, such as dengue virus infection, by administering an emetine compound such as emetine or cephaeline, or a combination of two or more emetine compounds, to a subject in need thereof; methods for inhibiting Flavivirus infections such as dengue virus infections in a cell in vitro or in vivo; pharmaceutical compositions; packaged dosage formulations; and kits for treating or preventing Flavivirus infections, such dengue virus infections.
FILED Wednesday, December 18, 2019
APPL NO 16/718343
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/4745 (20130101) Original (OR) Class
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207320 De Waal et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts);  Bayer Pharma Aktiengesellschaft (Berlin, Germany)
ASSIGNEE(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts);  Bayer Pharma Aktiengesellschaft (Berlin, Germany)
INVENTOR(S) Luc De Waal (Boston, Massachusetts);  Matthew Meyerson (Boston, Massachusetts);  Heidi Greulich (Boston, Massachusetts);  Monica Schenone (Boston, Massachusetts);  Alex Burgin (Cambridge, Massachusetts);  Xiaoyun Wu (Cambridge, Massachusetts);  Ulrike Sack (Monheim Am Rhein, Germany)
ABSTRACT The present invention features improved methods of identifying patients having cancer (e.g., melanoma, adenocarcinoma, lung, cervical, liver or breast cancer) using biomarkers (e.g., PDE3A, SLFN12) that correlate with drug sensitivity and consequently treating a stratified patient population with an agent of the invention (e.g., DNMDP, zardaverine, and anagrelide).
FILED Friday, August 12, 2016
APPL NO 15/752130
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/0053 (20130101)
A61K 31/50 (20130101) Original (OR) Class
A61K 31/519 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57488 (20130101)
G01N 2333/916 (20130101)
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207329 Rotolo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Sloan Kettering Institute for Cancer Research (New York, New York);  Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) SLOAN KETTERING INSTITUTE FOR CANCER RESEARCH (New York, New York);  BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Jimmy Andrew Rotolo (Port Washington, New York);  Richard N. Kolesnick (New York, New York);  Renata Pasqualini (Los Ranchos de Albuquerque, New Mexico);  Wadih Arap (Los Ranchos de Albuquerque, New Mexico)
ABSTRACT We have discovered that administering anti-ceramide antibody treats and prevents an array of diseases mediated by cytolytic T lymphocyte (CTLs)-induced killing and by damage to endothelial microvasculture, including radiation-induced GI syndrome, Graft vs. Host diseases, inflammatory diseases and autoimmune diseases. We have also discovered new anti-ceramide monoclonal antibodies, that have therapeutic use preferably in humanized form to treat or prevent these diseases.
FILED Tuesday, February 27, 2018
APPL NO 15/906868
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/55 (20130101) Original (OR) Class
A61K 2039/505 (20130101)

Peptides
C07K 16/28 (20130101)
C07K 16/40 (20130101)
C07K 16/44 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207339 Lobb et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland);  Aleta Biotherapeutics, Inc. (Natick, Massachusetts)
ASSIGNEE(S) The United States of America, as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland);  Aleta Biotherapeutics Inc. (Natick, Massachusetts)
INVENTOR(S) Roy Lobb (Westwood, Massachusetts);  Paul David Rennert (Holliston, Massachusetts);  John Todd Schiller (Kensington, Maryland)
ABSTRACT Some embodiments of the present disclosure are directed to methods that include delivering to a subject a nucleic acid encoding an antigen, wherein the nucleic acid is delivered via a tumor-selective vehicle or via intratumoral injection, and delivering to the subject an immune cell expressing a receptor that binds to the antigen.
FILED Friday, October 28, 2016
APPL NO 15/772134
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 31/7088 (20130101) Original (OR) Class
A61K 35/761 (20130101)
A61K 35/763 (20130101)
A61K 35/765 (20130101)
A61K 35/766 (20130101)
A61K 35/768 (20130101)
A61K 39/0011 (20130101)
A61K 39/00115 (20180801)
A61K 39/00116 (20180801)
A61K 39/00117 (20180801)
A61K 39/001104 (20180801)
A61K 39/001106 (20180801)
A61K 39/001109 (20180801)
A61K 39/001112 (20180801)
A61K 39/001113 (20180801)
A61K 39/001119 (20180801)
A61K 39/001122 (20180801)
A61K 39/001124 (20180801)
A61K 39/001166 (20180801)
A61K 39/001168 (20180801)
A61K 39/001171 (20180801)
A61K 39/001174 (20180801)
A61K 39/001182 (20180801)
A61K 39/001186 (20180801)
A61K 39/001188 (20180801)
A61K 39/001191 (20180801)
A61K 39/001192 (20180801)
A61K 39/001195 (20180801)
A61K 2039/5152 (20130101)
A61K 2039/5156 (20130101)
A61K 2039/5158 (20130101)

Peptides
C07K 14/70503 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207361 Chiorini et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The USA, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) John A. Chiorini (Dayton, Maryland);  Giovanni DiPasquale (Kensington, Maryland);  Edoardo Mannucci (Prato, Italy)
ABSTRACT The invention relates to a gene transfer-based method to protect a subject from diabetes or obesity. The method comprises administering to a salivary gland of the subject an AAV virion comprising an AAV vector that encodes an exendin-4 protein. Also provided are exendin-4 proteins and nucleic acid molecules that encode such exendin-4 proteins. Also provided are AAV vectors and AAV virions that encode an exendin-4 protein. One embodiment is an exendin-4 protein that is a fusion protein comprising an NGF secretory segment joined to the amino terminus of an exendin-4 protein domain.
FILED Friday, April 26, 2019
APPL NO 16/396262
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/76 (20130101) Original (OR) Class
A61K 35/761 (20130101)
A61K 38/1703 (20130101)
A61K 48/005 (20130101)
A61K 48/0075 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/04 (20130101)

Peptides
C07K 14/48 (20130101)
C07K 14/605 (20130101)
C07K 14/57563 (20130101)
C07K 2319/50 (20130101)
C07K 2319/055 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/79 (20130101)
C12N 15/86 (20130101)
C12N 2750/14143 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207374 Pamer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York)
ASSIGNEE(S) MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York)
INVENTOR(S) Eric Pamer (Montclair, New Jersey);  Sohn Kim (New York, New York);  Peter McKenney (New York, New York);  Silvia Caballero (Cambridge, Massachusetts)
ABSTRACT The present disclosure relates to novel lantibiotics, lantibiotic pharmaceutical compositions, isolated and recombinant lantibiotic-producing bacteria, bacterial pharmaceutical compositions, methods of producing novel lantibiotics from lantibiotic-producing bacteria, and methods of using such lantibiotics, lantibiotic pharmaceutical compositions, and bacterial pharmaceutical compositions to treat gram-positive bacteria infections, including vancomycin resistant enterococci infections, in patients, and to treat food and other objects to avoid gram-positive bacteria contamination.
FILED Monday, October 21, 2019
APPL NO 16/659199
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/12 (20130101) Original (OR) Class
A61K 38/443 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/20 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 21/00 (20130101)

Enzymes
C12Y 101/0112 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207378 Hewlett et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
ASSIGNEE(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S) Erik L. Hewlett (Charlottesville, Virginia);  Casandra L. Hoffman (Portland, Oregon)
ABSTRACT Provided are compositions that include an effective amount of a peptide or polypeptide derived from a Bordetella ACT AC domain, optionally wherein the peptide or polypeptide is 80-100% identical to an amino acid sequence as set forth in SEQ ID NOs: 1-5 and 44-53. Also provided are methods of using the same for preventing and/or treating a diseases, disorders, and conditions associated with the presence and/or development of biofilm; and for reducing the incidence of nosocomial infections; for inhibiting biofilm development and/or for reducing or eliminating biofilm present on medical, dental, and industrial surfaces.
FILED Tuesday, April 04, 2017
APPL NO 16/091046
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 25/28 (20130101)
A01N 63/10 (20200101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 38/164 (20130101) Original (OR) Class
A61K 39/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)
A61P 41/00 (20180101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 21/00 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/025 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207380 Debinski et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Wake Forest University Health Sciences (Winston-Salem, North Carolina)
ASSIGNEE(S) Wake Forest University Health Sciences (Winston-Salem, North Carolina)
INVENTOR(S) Waldemar Debinski (Winston-Salem, North Carolina);  Jill Wykosky (La Jolla, California);  Denise Mazess Herpai (Winston-Salem, North Carolina)
ABSTRACT The present invention provides compounds, compositions, and methods for detecting, diagnosing and treating cancers such as glioblastoma multiforme.
FILED Thursday, April 19, 2018
APPL NO 15/957445
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/45 (20130101)
A61K 38/177 (20130101) Original (OR) Class
A61K 38/2086 (20130101)
A61K 45/06 (20130101)
A61K 47/64 (20170801)
A61K 47/642 (20170801)
A61K 47/6801 (20170801)
A61K 49/0002 (20130101)

Peptides
C07K 14/52 (20130101)
C07K 14/705 (20130101)

Enzymes
C12Y 204/02036 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207393 Sharpe et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts);  Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts);  Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S) Arlene H. Sharpe (Brookline, Massachusetts);  Gordon J. Freeman (Brookline, Massachusetts);  Loise M. Francisco (Belmont, Massachusetts);  Peter T. Sage (Brookline, Massachusetts);  Sun J. Lee (Statesboro, Georgia);  Scott B. Lovitch (Somerville, Massachusetts);  Vikram R. Juneja (Boston, Massachusetts);  Catherine L. Tan (Boston, Massachusetts)
ABSTRACT The present invention is based, in part, on the identification of methods of modulating PD-1 expression and/or activity in regulatory T cells (Tregs) to thereby regulate effector immune responses in effector T cells (Teffs).
FILED Friday, October 14, 2016
APPL NO 15/768077
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 2227/105 (20130101)
A01K 2267/0325 (20130101)
A01K 2267/0331 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 35/17 (20130101)
A61K 38/1774 (20130101)
A61K 39/008 (20130101)
A61K 39/001129 (20180801) Original (OR) Class
A61K 39/39541 (20130101)
A61K 45/06 (20130101)
A61K 2039/5158 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
A61P 37/02 (20180101)

Peptides
C07K 14/00 (20130101)
C07K 14/70503 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207394 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Qiong J. Wang (Potomac, Maryland);  Zhiya Yu (Potomac, Maryland);  James C. Yang (Bethesda, Maryland)
ABSTRACT Disclosed is an isolated or purified T cell receptor (TCR) having antigenic specificity for an HLA-A11-restricted epitope of mutated Kirsten rat sarcoma viral oncogene homolog (KRAS) (KRAS7-16), Neuroblastoma RAS Viral (V-Ras) Oncogene Homolog (NRAS), or Harvey Rat Sarcoma Viral Oncogene Homolog (HRAS). Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal.
FILED Tuesday, November 24, 2015
APPL NO 15/528813
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 39/001164 (20180801) Original (OR) Class
A61K 2039/5152 (20130101)

Peptides
C07K 14/82 (20130101)
C07K 14/7051 (20130101)

Enzymes
C12Y 306/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5748 (20130101)
G01N 2333/914 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207395 Eappen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Congressionally Directed Medical Research Programs (CDMRP)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Sanaria Inc. (Rockville, Maryland)
ASSIGNEE(S) Sanaria Inc. (Rockville, Maryland)
INVENTOR(S) Abraham G. Eappen (Ellicott City, Maryland);  Stephen L. Hoffman (Gaithersburg, Maryland)
ABSTRACT The application is directed to in vitro-reared Plasmodium sporozoites of human host range wherein sporogony from gametocyte stage to sporozoite stage is external to mosquitoes, and methods of producing the same. Provided herein are in vitro-reared infectious Plasmodium sporozoites (SPZ) of human host range, particularly P. falciparum, P. vivax, P. ovale, P. malariae, and P. knowlesi, wherein sporogony from gametocyte stage to sporozoite stage is external to mosquitoes, and methods of producing the same.
FILED Thursday, September 05, 2019
APPL NO 16/561814
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/015 (20130101) Original (OR) Class
A61K 2039/52 (20130101)
A61K 2039/522 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/10 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207396 Orihuela et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S) The Board Of Regents Of The University Of Texas System (Austin, Texas);  St. Jude Children's Research Hospital (Memphis, Tennessee)
INVENTOR(S) Carlos J. Orihuela (San Antonio, Texas);  Elaine I. Tuomanen (San Antonio, Texas);  Armand O. Brown (San Antonio, Texas)
ABSTRACT In some aspects, provided herein are methods and compositions for treating or preventing adverse cardiac events in a patient who has suffered an invasive pneumococcal infection or is at risk of such an infection. The compositions include fusion proteins comprising a CbpA polypeptide or active fragment or variant thereof and optionally a T cell epitope (TCE) and a third immunogenic polypeptide from a bacteria.
FILED Monday, May 19, 2014
APPL NO 14/891814
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/092 (20130101) Original (OR) Class
A61K 45/06 (20130101)
A61K 2039/64 (20130101)
A61K 2039/6037 (20130101)

Peptides
C07K 14/3156 (20130101)
C07K 2319/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207400 Barouch et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Janssen Vaccines and Prevention B.V. (Leiden, Netherlands);  Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Janssen Vaccines and Prevention B.V. (Leiden, Netherlands);  Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts)
INVENTOR(S) Dan Barouch (Newton, Massachusetts);  Johanna Schuitemaker (Amstelveen, Netherlands);  Maria Grazia Pau (Leiden, Netherlands);  Danielle Van Manen (Leiden, Netherlands);  Frank Tomaka (Titusville, New Jersey);  Jennifer Anne Hendriks (Poeldijk, Netherlands)
ABSTRACT Compositions, vaccines and methods for inducing an immunity, including a protective immunity, against Human Immunodeficiency Virus (HIV) infection are described. Heterologous vaccine combinations of one or more adenovirus 26 vectors using for priming immunization and an isolated HIV antigenic polypeptide in combination with one or more MVA vectors for boosting immunization induced strong protective immunity against infections by one or multiple clades of HIV.
FILED Friday, October 04, 2019
APPL NO 16/593658
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/21 (20130101) Original (OR) Class
A61K 2039/575 (20130101)
A61K 2039/55505 (20130101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101)
C12N 2710/10043 (20130101)
C12N 2710/24143 (20130101)
C12N 2740/16034 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207402 Ertl et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Wistar Institute of Anatomy and Biology (Philadelphia, Pennsylvania)
INVENTOR(S) Hildegund C. J. Ertl (Villanova, Pennsylvania);  Marcio O. Lasaro (Maple Shade, New Jersey);  Luis C. S. Ferreira (Sao Paulo, Brazil)
ABSTRACT Chimeric protein constructs including a herpesvirus glycoprotein D (gD) and a heterologous polypeptide that interact with herpes virus entry mediator (HVEM) and enhance and enhance an immune response against the heterologous polypeptide and methods for their use are provided.
FILED Friday, May 10, 2019
APPL NO 16/408730
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/245 (20130101) Original (OR) Class
A61K 2039/53 (20130101)
A61K 2039/57 (20130101)

Peptides
C07K 14/005 (20130101)
C07K 2319/00 (20130101)
C07K 2319/10 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2710/10043 (20130101)
C12N 2710/16622 (20130101)
C12N 2710/16634 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207404 Burkhart et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) GLAXOSMITHKLINE BIOLOGICALS, SA (Rixensart, Belgium)
ASSIGNEE(S) GLAXOSMITHKLINE BIOLOGICALS SA (Rixensart, Belgium)
INVENTOR(S) David Burkhart (Research Triangle Park, North Carolina);  Michael Cochran (Research Triangle Park, North Carolina);  Christopher W Cluff (Research Triangle Park, North Carolina);  Daniel Larocque (Research Triangle Park, North Carolina);  Helene G. Bazin-Lee (Research Triangle Park, North Carolina);  Julien St-Jean (Research Triangle Park, North Carolina)
ABSTRACT The present invention relates to immunogenic compositions and methods for producing them, and in particular, immunogenic compositions comprising a protein antigen cross linked to an oxoadenine adjuvant.
FILED Wednesday, April 15, 2020
APPL NO 16/848910
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/52 (20130101)
A61K 31/522 (20130101)
A61K 39/39 (20130101) Original (OR) Class
A61K 2039/555 (20130101)
A61K 2039/627 (20130101)
A61K 2039/55511 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207418 Irvine et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Darrell J. Irvine (Arlington, Massachusetts);  Eric Dane (Cambridge, Massachusetts)
ABSTRACT The present disclosure provides a synthetic nanoparticle comprising a peptide nucleic acid (PNA) oligomer conjugated to a lipid, wherein the PNA oligomer noncovalently complexes with an immunomodulatory compound, thereby forming a nanoparticle. The nanoparticles are useful to elicit immune responses and can be used to treat a broad range of cancers and infectious diseases.
FILED Wednesday, April 10, 2019
APPL NO 16/380886
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5123 (20130101)
A61K 47/64 (20170801)
A61K 47/542 (20170801)
A61K 47/543 (20170801)
A61K 47/645 (20170801)
A61K 47/6425 (20170801) Original (OR) Class
A61K 47/6807 (20170801)
A61K 47/6911 (20170801)

Peptides
C07K 14/003 (20130101)
C07K 19/00 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 69/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207421 Lovell et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
NIH Office of the Director (NIHOD)
APPLICANT(S) The Research Foundation for The State University of New York (Buffalo, New York);  PATH (Seattle, Washington)
ASSIGNEE(S) The Research Foundation for The State University of New York (Amherst, New York);  PATH (Seattle, Washington)
INVENTOR(S) Jonathan Lovell (Niagara Falls, Canada);  Shuai Shao (Tonawanda, New York);  Jumin Geng (Williamsville, New York);  Wei-Chiao Huang (Amherst, New York);  Shwu-Maan Lee (Rockville, Maryland);  Charles Richter King (Washington, District of Columbia)
ABSTRACT The present disclosure provides nanostructures (e.g., monolayer or bilayer nanostructures) comprising porphyrins with cobalt chelated thereto such that the cobalt metal resides within monolayer or bilayer in the porphyrin macrocycle. The nanostructures can have presentation molecules comprising epitopes from microorganisms with a histidine tag attached thereto, such that at least a part of the his-tag is within the monolayer or bilayer and coordinated to the cobalt metal core and the presentation molecules are exposed to the outside of the nanostructures. The nanostructures can further comprise a cargo. The nanostructures can be used to deliver the cargo to an individual.
FILED Tuesday, April 30, 2019
APPL NO 16/399581
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/1271 (20130101)
A61K 39/02 (20130101)
A61K 39/145 (20130101)
A61K 39/155 (20130101)
A61K 47/6911 (20170801) Original (OR) Class
A61K 47/6929 (20170801)
A61K 2039/64 (20130101)
A61K 2039/552 (20130101)
A61K 2039/6018 (20130101)
A61K 2039/55505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)
A61P 31/14 (20180101)
A61P 31/16 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2760/16034 (20130101)
C12N 2760/16071 (20130101)
C12N 2760/18534 (20130101)
C12N 2760/18571 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207423 Henkin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Jack Henkin (Highland Park, Illinois);  Ignacio Melgar-Asensio (Chicago, Illinois)
ABSTRACT Disclosed are biodegradable nanocarriers that have a net positive surface charge and zeta potential between about +2 to about +20 mV. The positive surface charge of the nanocarriers is provided by peptides that are covalently attached to the surface of the nanocarriers. The nanocarriers may comprise a drug and may be administered for localized and sustained delivery of the drug.
FILED Tuesday, March 10, 2020
APPL NO 16/814567
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0048 (20130101)
A61K 9/0051 (20130101)
A61K 38/00 (20130101)
A61K 47/61 (20170801)
A61K 47/542 (20170801)
A61K 47/6903 (20170801)
A61K 47/6921 (20170801)
A61K 47/6935 (20170801)
A61K 47/6939 (20170801) Original (OR) Class

Peptides
C07K 7/06 (20130101)
C07K 14/47 (20130101)
C07K 14/75 (20130101)
C07K 14/78 (20130101)
C07K 14/811 (20130101)
C07K 14/8121 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207424 Ikeda et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota);  University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota);  University of Pittsburgh Of the Commonwealth System of Higher Educat (Pittsburgh, Pennsylvania)
INVENTOR(S) Yasuhiro Ikeda (Rochester, Minnesota);  Claire A. Schreiber (Rochester, Minnesota);  Toshie Sakuma (Rochester, Minnesota);  Sara J. Holditch (Rochester, Minnesota);  Kazunori Koide (Pittsburgh, Pennsylvania)
ABSTRACT This document relates to methods and materials for increasing viral vector infectivity. For example, methods and materials for using spliceosome inhibitors (e.g., U2 snRNP spliceosome inhibitors such as meayamycin B or pladienolide derivative E7107) to increase viral vector (e.g., adeno-associated virus-based vector) infectivity are provided.
FILED Friday, June 12, 2015
APPL NO 15/318618
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/5377 (20130101)
A61K 38/00 (20130101)
A61K 48/00 (20130101) Original (OR) Class
A61K 48/0083 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
C12N 2750/14143 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207426 Szabo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Gyongyi Szabo (Worcester, Massachusetts);  Guangping Gao (Westborough, Massachusetts);  Abhishek Satishchandran (Worcester, Massachusetts)
ABSTRACT In some aspects, the disclosure relates to methods and compositions for modulation of miR-122 expression in a cell or a subject. In some embodiments, methods and compositions described by the disclosure are useful for the treatment of liver-associated diseases (e.g., chronic liver disease, alcoholic liver disease).
FILED Wednesday, April 05, 2017
APPL NO 16/091675
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 31/713 (20130101)
A61K 31/7105 (20130101)
A61K 47/6807 (20170801)
A61K 48/0016 (20130101)
A61K 48/0058 (20130101) Original (OR) Class
A61K 48/0075 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 1/16 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/067 (20130101)
C12N 15/113 (20130101)
C12N 2310/113 (20130101)
C12N 2310/141 (20130101)
C12N 2750/14143 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207428 Yantasee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) PDX Pharmaceuticals, Inc. (Portland, Oregon);  Oregon Health and Science University (Portland, Oregon)
ASSIGNEE(S) Oregon Health and Science University (Portland, Oregon);  PDX Pharmaceuticals, Inc. (Portland, Oregon)
INVENTOR(S) Wassana Yantasee (Lake Oswego, Oregon);  Worapol Ngamcherdtrakul (Portland, Oregon);  Jingga Morry (Portland, Oregon);  David Castro (Portland, Oregon);  Joe Gray (Lake Oswego, Oregon)
ABSTRACT Disclosed herein are nanoconstructs comprising a nanoparticle, coated with additional agents such as cationic polymers, stabilizers, targeting molecules, labels, oligonucleotides and small molecules. These constructs may be used to deliver compounds to treat solid tumors and to diagnose cancer and other diseases. Further disclosed are methods of making such compounds and use of such compounds to treat or diagnose human disease.
FILED Friday, February 10, 2017
APPL NO 15/429971
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/713 (20130101)
A61K 38/16 (20130101)
A61K 47/59 (20170801)
A61K 47/60 (20170801)
A61K 47/551 (20170801)
A61K 47/6849 (20170801)
A61K 47/6855 (20170801)
A61K 47/6923 (20170801)
A61K 47/6929 (20170801)
A61K 49/0093 (20130101) Original (OR) Class
A61K 49/186 (20130101)
A61K 49/1857 (20130101)
A61K 49/1875 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)
B82Y 30/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207429 Mash et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona);  H. Lee Moffitt Cancer Center and Research Institute (Tampa, Florida)
ASSIGNEE(S) Arizona Board of Regents on behalf of the University of Arizona (Tucson, Arizona)
INVENTOR(S) Eugene A. Mash (Tucson, Arizona);  Parastou Foroutan (Tampa, Florida);  Suryakiran Navath (Tucson, Arizona);  Robert J. Gillies (Tampa, Florida);  Gary V. Martinez (Tampa, Florida);  David L. Morse (Tampa, Florida)
ABSTRACT Disclosed is CT or MR contrast agent which comprises a base or carrier scaffold formed of a polyhydroxol compound having a linker to which a Gd-DOTA is covalently bonded. Also disclosed is a method of screening a patient for colon cancer using a CT or MR contrast, which method comprises administering to a patient undergoing screening a compound as above described.
FILED Monday, May 11, 2015
APPL NO 15/316810
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/085 (20130101)
A61K 49/108 (20130101) Original (OR) Class
A61K 49/124 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207430 Ho et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Rodney J. Y. Ho (Mercer Island, Washington);  John D. Hoekman (Seattle, Washington);  Ken Maravilla (Bellevue, Washington)
ABSTRACT Lipid nanoparticles expressing metal ions and methods for using the compositions for magnetic resonance imaging.
FILED Monday, December 05, 2016
APPL NO 15/369661
ART UNIT 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/085 (20130101)
A61K 49/1806 (20130101)
A61K 49/1812 (20130101)
A61K 49/1824 (20130101) Original (OR) Class
A61K 49/1881 (20130101)
A61K 51/0408 (20130101)
A61K 51/0497 (20130101)
A61K 51/1227 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207431 Hooker et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Jacob Hooker (Belmont, Massachusetts);  Changning Wang (Melrose, Massachusetts);  Martin Georg Strebl-Bantillo (Somerville, Massachusetts)
ABSTRACT Provided herein are compounds useful for binding to one or more histone deacetylase enzymes (HDACs). The present application further provides radiolabeled compounds useful as a radiotracer for position emission tomography imaging of HDAC. Methods for prepared unlabeled and labeled compounds, diagnostic methods, and methods of treating diseases associated HDAC are also provided.
FILED Wednesday, April 11, 2018
APPL NO 16/603746
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 51/04 (20130101) Original (OR) Class

General Methods of Organic Chemistry; Apparatus Therefor
C07B 2200/05 (20130101)

Acyclic or Carbocyclic Compounds
C07C 259/10 (20130101)
C07C 2602/42 (20170501)
C07C 2603/74 (20170501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207433 Liu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Yongjian Liu (St. Louis, Missouri);  Pamela K. Woodard (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Yongjian Liu (St. Louis, Missouri);  Pamela K. Woodard (St. Louis, Missouri)
ABSTRACT The present invention relates to various compositions and methods of using these compositions for imaging natriuretic peptide receptors using, for example, positron emission tomography.
FILED Friday, June 21, 2019
APPL NO 16/449147
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 51/025 (20130101)
A61K 51/088 (20130101) Original (OR) Class
A61K 51/1244 (20130101)

Measurement of Nuclear or X-radiation
G01T 1/2985 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207519 Joyner et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S) Michael j. Joyner (Rochester, Minnesota);  Bruce D. Johnson (Rochester, Minnesota);  Thomas P. Olson (Cannon Falls, Minnesota)
ABSTRACT This document provides methods and materials for modulating afferent nerve signals to treat medical conditions such as CHF, CHF respiration, dyspnea, peripheral vascular disease (e.g., peripheral arterial disease or venous insufficiency), hypertension (e.g., age-associated hypertension, resistant hypertension, or chronic refractory hypertension), COPD, sleep apnea, and chronic forms of lung disease where muscle dysfunction is a part of the disease pathophysiology. For example, methods and materials involved in using electrical and/or chemical techniques to block or reduce afferent nerve signals (e.g., nerve signals of group III and/or IV afferents coming from skeletal muscle and/or the kidneys) are provided.
FILED Tuesday, May 21, 2019
APPL NO 16/418307
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/245 (20130101)
A61K 31/4468 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/3611 (20130101)
A61N 1/36057 (20130101)
A61N 1/36114 (20130101) Original (OR) Class
A61N 1/36117 (20130101)
A61N 1/36146 (20130101)
A61N 2/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207655 Jones et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) BioFire Diagnostics, LLC (Salt Lake City, Utah)
ASSIGNEE(S) BioFire Diagnostics, LLC (Salt Lake City, Utah)
INVENTOR(S) David E. Jones (Layton, Utah);  Kirk Max Ririe (Salt Lake City, Utah);  Thomas Charles Robbins (Salt Lake City, Utah);  Elizabeth Doman Copene (Salt Lake City, Utah);  Charles Benjamin Cox (Sandy, Utah)
ABSTRACT Devices and methods are provided for spotting an array with fluid. Arrays produced by such methods are also provided. In one aspect of the invention, a spotter device for spotting a plurality of fluids into an array is described, the spotter device comprising a plurality of reservoirs provided in a first configuration, each reservoir holding its respective fluid, a print head having a plurality of positions provided in a second configuration, the second configuration being different from the first configuration, a plurality of tubes, each tube configured to provide fluid communication from a reservoir at a first end of the tube to a position in the print head at the second end of the tube, and a pump for pumping fluid through the tubes from the reservoir to the print head.
FILED Friday, October 11, 2019
APPL NO 16/599352
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/0046 (20130101) Original (OR) Class
B01J 2219/00313 (20130101)
B01J 2219/00355 (20130101)
B01J 2219/00376 (20130101)
B01J 2219/00385 (20130101)
B01J 2219/00585 (20130101)
B01J 2219/00693 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/0262 (20130101)
B01L 3/0265 (20130101)
B01L 2200/16 (20130101)
B01L 2300/0861 (20130101)
B01L 2300/1822 (20130101)
B01L 2300/1827 (20130101)
B01L 2400/0478 (20130101)
B01L 2400/0487 (20130101)
B01L 2400/0605 (20130101)
B01L 2400/0616 (20130101)
B01L 2400/0655 (20130101)
B01L 2400/0677 (20130101)
B01L 2400/0683 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207676 Saunders
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Marnie M. Saunders (Canton, Ohio)
ASSIGNEE(S) The University of Akron (Akron, Ohio)
INVENTOR(S) Marnie M. Saunders (Canton, Ohio)
ABSTRACT A lab-on-a-chip (LOC) for the biomimetic study of the multicellular interactions of bone cells includes a PDMS substrate and cap, which together form one or more wells that are fluidly coupled by tubes. The wells are configured to support various bone cells and related cellular support substrates therein, while the tubes allow conditioned medium (CM), including soluble signals, and various other co-factors to be communicated among the various wells. By controlling the configuration among and between various bone cells in the wells, the temporal and spatial limitations associated with traditional in vivo bone tissue models is removed. In addition, the LOC enables a particular research objective to be studied by allowing the user to configure the arrangement of the wells/tubes of the LOC, so as to control the manner in which bone cell soluble signals, bone cell contact, and bone cell matrix interaction interplay.
FILED Thursday, April 26, 2018
APPL NO 15/963360
ART UNIT 1799 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5027 (20130101) Original (OR) Class
B01L 3/502761 (20130101)
B01L 2300/16 (20130101)
B01L 2300/042 (20130101)
B01L 2300/163 (20130101)
B01L 2300/0829 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 21/08 (20130101)
C12M 23/12 (20130101)
C12M 23/16 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0068 (20130101)
C12N 5/0643 (20130101)
C12N 5/0654 (20130101)
C12N 2533/30 (20130101)
C12N 2533/54 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207679 Dorfman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Kevin David Dorfman (Edina, Minnesota);  Paridhi Agrawal (Minneapolis, Minnesota)
ABSTRACT A DNA extraction device may include a substrate, at least one first side channel electrode, at least one second side channel electrode, optionally, at least one elongate central channel electrode, and a voltage source connected between the electrodes. The substrate defines an elongate central channel defining a major axis. A width of the elongate central channel is greater than its depth, and its depth is less than about 15 times a diameter of a cell to be introduced in the elongate central channel. The substrate also defines first and second side channels adjacent to the elongate central channel on opposite sides of the major axis. The substrate further defines first and second trapezoidally shaped connecting channels connecting the elongate central channel and the first and second side channels, respectively. The smaller parallel sides of the first and second trapezoidally shaped connecting channels open to the respective side channels.
FILED Friday, April 12, 2019
APPL NO 16/383129
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502715 (20130101) Original (OR) Class
B01L 2300/0645 (20130101)
B01L 2300/0861 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1003 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208330 Nel et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
APPLICANT(S) The Regents of the University of California (Oakland, California);  Northwestern University (Evanston, Illinois)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  Northwestern University (Evanston, Illinois)
INVENTOR(S) Andre E. Nel (Sherman Oaks, California);  Tian Xia (Los Angeles, California);  Ruibin Li (Los Angeles, California);  Mark C. Hersam (Wilmette, Illinois);  Nikhita D. Mansukhani (Allston, Massachusetts);  Linda Guiney (Chicago, Illinois)
ABSTRACT In various embodiments functionalized graphene oxide(s) are provided that demonstrate improved antimicrobial activity, where the graphene oxide(s) are functionalized to increase carbon radical (.C) density.
FILED Wednesday, November 15, 2017
APPL NO 16/348862
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 43/90 (20130101)
A01N 59/00 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/08 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/198 (20170801) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208386 Thompson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Paul R. Thompson (Wellesley, Massachusetts);  Aaron Muth (Brighton, Massachusetts);  Venkataraman Subramanian (Worcester, Massachusetts)
ABSTRACT The invention provides novel inhibitors or inactivators of protein arginine deiminases, pharmaceutical compositions and methods of use thereof. The invention also relates to molecular probes based on such compounds and methods of use thereof.
FILED Monday, November 27, 2017
APPL NO 16/464317
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 235/14 (20130101) Original (OR) Class
C07D 403/12 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/34 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/582 (20130101)
G01N 2333/978 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208390 Hilderbrand et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Research Service Award (NRSA)
Institutional Research Training Grant (T32)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Scott A. Hilderbrand (Swampscott, Massachusetts);  Neal K. Devaraj (Boston, Massachusetts);  Ralph Weissleder (Peabody, Massachusetts);  Mark R. Karver (Chicago, Illinois)
ABSTRACT The present application relates to functionalized 1,2,4,5-tetrazine compounds. The compounds are useful in compositions and methods using bioorthogonal inverse electron demand Diels-Alder cycloaddition reactions for the rapid and specific covalent delivery of a “payload” to a ligand bound to a biological target.
FILED Monday, March 02, 2020
APPL NO 16/807037
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 257/08 (20130101) Original (OR) Class
C07D 401/04 (20130101)
C07D 403/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208411 Rutaganira et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California);  Washington University (St. Louis, Missouri)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  Washington University (St. Louis, Missouri)
INVENTOR(S) Florentine Rutaganira (Woodland, California);  Kevan M. Shokat (San Francisco, California);  Laurence David Sibley (St. Louis, Missouri);  James W. Janetka (St. Louis, Missouri)
ABSTRACT Disclosed herein, inter alia, are compositions and methods for treating parasitic diseases.
FILED Friday, March 17, 2017
APPL NO 16/085981
ART UNIT 1699 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/42 (20130101)
A61K 31/505 (20130101)
A61K 31/7056 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 33/02 (20180101)

Heterocyclic Compounds
C07D 487/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208435 Johnston et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of General Medical Sciences (NIGMS)
National Institute of Neurological Disorders and Stroke (NINDS)
National Research Service Award (NRSA)
Institutional Research Training Grant (T32)
APPLICANT(S) Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) Jeffrey N. Johnston (Nashville, Tennessee);  Suzanne Batiste (Nashville, Tennessee);  Bjorn C. Knollmann (Bethesda, Maryland);  Daniel J Blackwell (Nashville, Tennessee);  Nieves Gomez-Hurtado (Nashville, Tennessee)
ABSTRACT The non-natural enantiomer (ent-(+)-verticilide) and uses for treatment of RyR2-mediated spontaneous Ca2+ leak, arrhythmia and memory loss.
FILED Monday, June 25, 2018
APPL NO 16/626073
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/06 (20180101)

Peptides
C07K 11/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208438 Asokan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina);  University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina);  University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Aravind Asokan (Chapel Hill, North Carolina);  Mavis Agbandje-McKenna (Gainesville, Florida);  Long Ping Victor Tse (Carrboro, North Carolina);  Brittney Gurda (Collegeville, Pennsylvania)
ABSTRACT The present invention provides AAV capsid proteins comprising a modification in the amino acid sequence and virus vectors comprising the modified AAV capsid protein. The invention also provides methods of administering the virus vectors and virus capsids of the invention to a cell or to a subject in vivo.
FILED Monday, July 06, 2020
APPL NO 16/921239
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/505 (20130101)
A61K 2039/507 (20130101)

Peptides
C07K 14/005 (20130101) Original (OR) Class
C07K 16/081 (20130101)
C07K 2317/33 (20130101)
C07K 2317/34 (20130101)
C07K 2317/76 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
C12N 2750/14122 (20130101)
C12N 2750/14143 (20130101)
C12N 2810/6027 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208445 Guillemin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) University of Oregon (Eugene, Oregon)
ASSIGNEE(S) University of Oregon (Eugene, Oregon)
INVENTOR(S) Karen Guillemin (Eugene, Oregon);  Annah Rolig (Eugene, Oregon);  Emily Sweeney (Eugene, Oregon)
ABSTRACT Methods of treating or inhibiting inflammation in a subject include administering an anti-inflammatory protein to the subject. In some embodiments, the protein has at least 80% sequence identity to the amino acid sequence set forth as SEQ ID NO: 1, SEQ ID NO: 17, or fragments thereof. Isolated polypeptides, nucleic acids, and recombinant vectors including a nucleic acid encoding the anti-inflammatory protein (such as a nucleic acid encoding a protein with at least 80% sequence identity to SEQ ID NO: 1, SEQ ID NO: 17, or fragments thereof) operably linked to a heterologous promoter are also disclosed.
FILED Thursday, July 30, 2020
APPL NO 16/943763
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 29/00 (20180101)

Peptides
C07K 4/12 (20130101)
C07K 14/4702 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/70 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208453 Weiss
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S) Michael A. Weiss (Moreland Hills, Ohio)
ABSTRACT A two-chain insulin analogue contains a modified A-chain polypeptide and a modified B-chain polypeptide. The A-chain polypeptide comprises one or more of: a His or Glu substitution at position A8, a Glu substitution at position A14; and a Gln or Arg substitution at positon A17. The B-chain polypeptide comprises one or more of: a deletion of the amino acids at position B1, B1-B2, B1-B3, B30 or a combination thereof; an Ala or Glu substitution at position B2; a Glu substitution at position B3. The analogue exhibits thermodynamic stability in a zinc-free solution, decreased self-association, maintains biological potency, and no increased mitogenicity. The analogue exhibits resistance to chemical degradation and physical degradation. A method of treating a patient with diabetes mellitus or obesity comprises administering a physiologically effective amount of the insulin analogue or a physiologically acceptable salt thereof to a patient.
FILED Tuesday, November 21, 2017
APPL NO 16/462440
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 3/10 (20180101)

Peptides
C07K 14/62 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208454 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
ASSIGNEE(S) TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
INVENTOR(S) Tong Zhang (Beijing, China PRC);  Charles L. Sentman (Grantham, New Hampshire)
ABSTRACT The present invention relates to chimeric immune receptor molecules for reducing or eliminating tumors. The chimeric receptors are composed a C-type lectin-like natural killer cell receptor, or a protein associated therewith, fused to an immune signaling receptor containing an immunoreceptor tyrosine-based activation motif. Methods for using the chimeric receptors are further provided.
FILED Friday, May 17, 2019
APPL NO 16/415309
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101)
A61K 38/10 (20130101)
A61K 45/06 (20130101)

Peptides
C07K 14/705 (20130101) Original (OR) Class
C07K 14/715 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208456 Tran et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Eric Tran (Portland, Oregon);  Yong-Chen Lu (Rockville, Maryland);  Anna Pasetto (Stockholm, Sweden);  Paul F. Robbins (Chevy Chase, Maryland);  Steven A. Rosenberg (Potomac, Maryland);  Zhili Zheng (Gaithersburg, Maryland)
ABSTRACT Disclosed is an isolated or purified T cell receptor (TCR) having antigenic specificity for mutated Kirsten rat sarcoma viral oncogene homolog (KRAS) presented in the context of an HLA-Cw*0802 molecule. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal.
FILED Thursday, April 02, 2020
APPL NO 16/838395
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/82 (20130101)
C07K 14/7051 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/85 (20130101)
C12N 2015/8518 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57407 (20130101)
G01N 2333/7051 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208468 Somasundaram et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Wistar Institute of Anatomy and Biology (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Wistar Institute of Anatomy and Biology (Philadelphia, Pennsylvania)
INVENTOR(S) Rajasekharan Somasundaram (West Chester, Pennsylvania);  Meenhard Herlyn (Wynnewood, Pennsylvania);  Dorothee Herlyn (Wynnewood, Pennsylvania)
ABSTRACT Compositions and methods for treating melanoma are provided. Compositions include BRAFV600E-based peptides, alone or admixed with T helper peptides. Other compositions include nucleic acid sequences encoding the BRAFV600E-based peptides, alone or admixed with nucleic acid sequences T helper peptides. Dendritic cells pretreated with the BRAFV600E-based peptides, alone or admixed with T helper peptides, are also provided. These compositions are useful to treat melanoma, optionally co-administered with antibodies to checkpoint inhibitors or molecules that mimic the action of such antibodies.
FILED Thursday, February 16, 2017
APPL NO 15/998913
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/127 (20130101)
A61K 35/15 (20130101)
A61K 38/1709 (20130101)
A61K 39/39541 (20130101)
A61K 39/39541 (20130101)
A61K 2039/505 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/82 (20130101) Original (OR) Class
C07K 16/2818 (20130101)
C07K 2317/76 (20130101)
C07K 2319/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/12 (20130101)

Enzymes
C12Y 207/11001 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208472 Fertala et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) Thomas Jefferson University (Philadelphia, Pennsylvania)
ASSIGNEE(S) Thomas Jefferson University (Philadelphia, Pennsylvania)
INVENTOR(S) Andrzej Fertala (Voorhees, New Jersey);  Andrzej Steplewski (Phoenixville, Pennsylvania)
ABSTRACT A chimeric, humanized or single-chain antibody contains a light chain variable region containing the complementarity determining regions of SEQ ID NO: 1, SEQ ID NO:2 and SEQ ID NO:3, and a heavy chain variable region containing the complementarity determining regions SEQ ID NO:5 and SEQ ID NO:6. The antibody or antibody fragment thereof is capable of binding the C-terminal telopeptide of the α2(I) chain of human collagen I, and is useful in the treatment of diseases or disorders associated with excessive collagen fibril.
FILED Friday, December 06, 2019
APPL NO 16/705538
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/505 (20130101)

Peptides
C07K 16/18 (20130101) Original (OR) Class
C07K 2317/24 (20130101)
C07K 2317/76 (20130101)
C07K 2317/92 (20130101)
C07K 2317/565 (20130101)
C07K 2317/622 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208478 Altieri
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Wistar Institute of Anatomy and Biology (Philadelphia, Pennsylvania)
ASSIGNEE(S) THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (Philadelphia, Pennsylvania)
INVENTOR(S) Dario C. Altieri (Philadelphia, Pennsylvania)
ABSTRACT Therapeutic treatments of a tumor expressing pT346 PDK1, including glioma expressing pT346 PDK1, are disclosed.
FILED Friday, August 04, 2017
APPL NO 16/323648
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/19 (20130101)
A61K 31/19 (20130101)
A61K 31/20 (20130101)
A61K 31/20 (20130101)
A61K 31/167 (20130101)
A61K 31/167 (20130101)
A61K 31/385 (20130101)
A61K 31/385 (20130101)
A61K 31/444 (20130101)
A61K 31/444 (20130101)
A61K 31/496 (20130101)
A61K 31/496 (20130101)
A61K 31/519 (20130101)
A61K 31/519 (20130101)
A61K 31/4439 (20130101)
A61K 31/4439 (20130101)
A61K 31/5383 (20130101)
A61K 31/5383 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 16/28 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/573 (20130101)
G01N 33/574 (20130101)
G01N 33/57407 (20130101)
G01N 2333/91205 (20130101)
G01N 2440/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208481 Ring et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Aaron Michael Ring (New Haven, Connecticut);  Kenan Christopher Garcia (Menlo Park, California);  Kipp Andrew Weiskopf (Brookline, Massachusetts);  Aron M. Levin (Cambridge, Massachusetts);  Irving L. Weissman (Stanford, California)
ABSTRACT High affinity SIRP-α reagent are provided, which (i) comprise at least one amino acid change relative to the wild-type protein; and (ii) have an increased affinity for CD47 relative to the wild-type protein. Compositions and methods are provided for modulating phagocytosis in a mammal by administering a therapeutic dose of a pharmaceutical composition comprising a high affinity SIRPα reagent, which blocks the physiological binding interaction between SIRPα and its ligand CD47.
FILED Monday, March 05, 2018
APPL NO 15/912471
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/16 (20130101)

Peptides
C07K 14/4703 (20130101)
C07K 16/2803 (20130101) Original (OR) Class
C07K 2317/52 (20130101)
C07K 2319/30 (20130101)

Enzymes
C12Y 301/03048 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208488 Rosenthal et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) Alector LLC (South San Francisco, California)
ASSIGNEE(S) Alector LLC (South San Francisco, California)
INVENTOR(S) Arnon Rosenthal (Woodside, California);  Tina Schwabe (San Francisco, California);  Michael Kurnellas (San Francisco, California);  Robert Pejchal (Lebanon, New Hampshire);  Anthony B. Cooper (Lebanon, New Hampshire)
ABSTRACT The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind on or more epitopes within a Sortilin protein, e.g., human Sortilin or a mammalian Sortilin, and use of such compostions in preventing, reducing risk, or treating an individual in need thereof.
FILED Tuesday, September 18, 2018
APPL NO 16/134830
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7088 (20130101)

Peptides
C07K 16/286 (20130101)
C07K 16/2863 (20130101) Original (OR) Class
C07K 2317/14 (20130101)
C07K 2317/21 (20130101)
C07K 2317/31 (20130101)
C07K 2317/34 (20130101)
C07K 2317/55 (20130101)
C07K 2317/56 (20130101)
C07K 2317/76 (20130101)
C07K 2317/92 (20130101)
C07K 2319/30 (20130101)
C07K 2319/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208493 Liu
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Bin Liu (San Francisco, California)
ABSTRACT In various embodiments various cancer specific antibodies and immunoconjugates are provided. In certain embodiments the antibodies specifically bind and are internalized into a prostate cancer cell, where the antibodies specifically binds cells that express or overexpress a CD46, and where the antibodies specifically bind sushi domain 1 of said CD46 (CD46 CPP1).
FILED Friday, July 19, 2019
APPL NO 16/517401
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/6803 (20170801)
A61K 47/6811 (20170801)
A61K 47/6829 (20170801)
A61K 47/6849 (20170801)
A61K 47/6869 (20170801)
A61K 51/1072 (20130101)
A61K 51/1093 (20130101)
A61K 51/1096 (20130101)

Peptides
C07K 16/2896 (20130101) Original (OR) Class
C07K 16/3069 (20130101)
C07K 2317/21 (20130101)
C07K 2317/34 (20130101)
C07K 2317/56 (20130101)
C07K 2317/77 (20130101)
C07K 2317/565 (20130101)
C07K 2317/567 (20130101)
C07K 2317/622 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57434 (20130101)
G01N 33/57492 (20130101)
G01N 2333/70596 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208634 Vallera
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Daniel Attilio Vallera (Richfield, Minnesota)
ABSTRACT This disclosure provides a bispecific ligand directed toxin (BLT) that includes a diphtheria toxin (DT) molecule that has been mutated to create a DT molecule that induces less of an immune response than native diphtheria toxin. The deimmunized DT molecule is fused with targeting ligands to create a fusion protein that can selectively deliver the deimmunized DT to target cells to kill the target cells.
FILED Friday, September 30, 2016
APPL NO 15/764047
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 47/6829 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/34 (20130101)
C07K 14/485 (20130101)
C07K 14/5437 (20130101)
C07K 2319/01 (20130101)
C07K 2319/33 (20130101)
C07K 2319/55 (20130101)
C07K 2319/74 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1077 (20130101) Original (OR) Class

Enzymes
C12Y 204/02036 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208652 Church et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) George M. Church (Brookline, Massachusetts);  Luhan Yang (Somerville, Massachusetts);  Margo R. Monroe (Boston, Massachusetts)
ABSTRACT Methods and compositions of altering mitochondrial DNA of a eukaryotic cell are provided using one or more of a mitochondrial specific adeno-associated virus to deliver one or more nucleic acids encoding CRISPR system including a Cas9 protein or its nuclease inactive variant and a guide RNA into a mitochondria for expression within the mitochondria. The Cas9 system can cut, nick or regulate a target mitochondrial nucleic acid.
FILED Thursday, February 02, 2017
APPL NO 16/075247
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 48/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 9/22 (20130101)
C12N 15/63 (20130101)
C12N 15/102 (20130101)
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/20 (20170501)
C12N 2750/14143 (20130101)
C12N 2800/80 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208653 Chen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Whitehead Institute for Biomedical Research (Cambridge, Massachusetts)
ASSIGNEE(S) Whitehead Institute for Biomedical Research (Cambridge, Massachusetts)
INVENTOR(S) Grace Chen (Somerville, Massachusetts);  David Bartel (Brookline, Massachusetts);  Hazel Sive (Newton, Massachusetts)
ABSTRACT Methods and compositions for increasing RNAi efficiency through single nucleotide mismatches.
FILED Thursday, April 27, 2017
APPL NO 16/097179
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/14 (20130101)
C12N 2320/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208654 Yu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) CITY OF HOPE (Duarte, California)
ASSIGNEE(S) CITY OF HOPE (Duarte, California)
INVENTOR(S) Hua Yu (Glendora, California);  Marcin Kortylewski (Monrovia, California);  Richard Jove (Pasadena, California);  Piotr Marek Swiderski (San Dimas, California);  John J. Rossi (Azusa, California)
ABSTRACT The present invention relates to methods and compositions for the treatment of diseases, including cancer, infectious diseases and autoimmune diseases. The present invention also relates to methods and compositions for improving immune function. More particularly, the present invention relates to multifunctional molecules that are capable of being delivered to cells of interest for the treatment of diseases and for the improvement in immune function.
FILED Wednesday, March 06, 2019
APPL NO 16/294537
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/713 (20130101)
A61K 31/7105 (20130101)
A61K 47/55 (20170801)
A61K 47/61 (20170801)
A61K 47/64 (20170801)
A61K 47/549 (20170801)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/02 (20130101)

Peptides
C07K 14/47 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 15/1135 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208661 Zhao et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Yangbing Zhao (Lumberton, New Jersey);  Jiangtao Ren (Philadelphia, Pennsylvania);  Xiaojun Liu (Swarthmore, Pennsylvania);  Carl H. June (Merion Station, Pennsylvania)
ABSTRACT The present invention relates to compositions and methods for generating a modified T cell with a nucleic acid capable of downregulating endogenous gene expression selected from the group consisting of TCR α chain, TCR β chain, beta-2 microglobulin and FAS further comprising a nucleic acid encoding a modified T cell receptor (TCR) comprising affinity for a surface antigen on a target cell or an electroporated nucleic acid encoding a chimeric antigen receptor (CAR). Also included are methods and pharmaceutical compositions comprising the modified T cell for adoptive therapy and treating a condition, such as an autoimmune disease.
FILED Thursday, October 15, 2015
APPL NO 15/516052
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101)
A61K 35/26 (20130101)
A61K 39/001102 (20180801)
A61K 2039/5156 (20130101)
A61K 2039/5158 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
A61P 37/06 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/85 (20130101)
C12N 15/1138 (20130101) Original (OR) Class
C12N 2310/10 (20130101)
C12N 2310/20 (20170501)
C12N 2501/48 (20130101)
C12N 2501/515 (20130101)
C12N 2501/599 (20130101)
C12N 2501/998 (20130101)
C12N 2510/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208664 Voigt et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Christopher Voigt (Belmont, Massachusetts);  Mao Taketani (Cambridge, Massachusetts)
ABSTRACT The present disclosure relates, in some aspects, to bile acid sensors.
FILED Tuesday, September 12, 2017
APPL NO 15/701498
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 49/0097 (20130101)

Peptides
C07K 14/28 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/74 (20130101) Original (OR) Class
C12N 15/635 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6897 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208676 Xuan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Feng Xuan (Boston, Massachusetts);  Peng Yin (Brookline, Massachusetts);  Mingjie Dai (Brookline, Massachusetts);  Xi Chen (West Newton, Massachusetts)
ABSTRACT The present disclosure provides, in some embodiments, methods and compositions for single-molecule detection.
FILED Friday, May 26, 2017
APPL NO 16/304323
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6804 (20130101) Original (OR) Class
C12Q 1/6804 (20130101)
C12Q 2525/186 (20130101)
C12Q 2525/301 (20130101)
C12Q 2531/119 (20130101)
C12Q 2565/514 (20130101)

Combinatorial Chemistry; Libraries, e.g Chemical Libraries
C40B 70/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208681 Blattman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
ASSIGNEE(S) Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) Joseph Blattman (Scottsdale, Arizona);  Louis Schoettle (Tempe, Arizona)
ABSTRACT Methods for incorporation of unique bowtie-barcodes into a nucleic acid origami nanostructure (FIG. 1). In particular, provided herein are methods that facilitate pairing and analysis of nucleic acids from individual cells using, for example, high-throughput next-generation sequencing.
FILED Monday, August 14, 2017
APPL NO 16/320962
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/87 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101) Original (OR) Class
C12Q 1/6869 (20130101)
C12Q 1/6869 (20130101)
C12Q 2563/159 (20130101)
C12Q 2563/179 (20130101)
C12Q 2565/133 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208683 Rao et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Children's Medical Center Corporation (Boston, Massachusetts);  The United States of America, As Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The Children's Medical Center Corporation (Boston, Massachusetts);  The United States of America, As Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Anjana Rao (La Jolla, California);  Mamta Tahiliani (New York, New York);  Kian Peng Koh (Jamaica Plain, Massachusetts);  Suneet Agarwal (Belmont, Massachusetts);  Aravind Iyer (Bethesda, Maryland)
ABSTRACT The present invention provides for methods of epigenetic analysis. In some cases, the methods may include obtaining a sample comprising a nucleic acid sequence. In some cases, the nucleic acid sequence may comprise one or more epigenetic marks. The methods may include performing a sequencing. The methods may include distinguishing a hydroxymethylated base from a methylated base.
FILED Thursday, April 15, 2021
APPL NO 17/231671
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1007 (20130101)
C12N 2501/70 (20130101)
C12N 2501/71 (20130101)
C12N 2501/724 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/26 (20130101)
C12Q 1/6806 (20130101)
C12Q 1/6827 (20130101) Original (OR) Class
C12Q 1/6827 (20130101)
C12Q 1/6869 (20130101)
C12Q 2521/531 (20130101)
C12Q 2521/531 (20130101)
C12Q 2522/10 (20130101)
C12Q 2522/10 (20130101)
C12Q 2537/164 (20130101)
C12Q 2537/164 (20130101)
C12Q 2600/154 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5308 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208691 Ju et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Jingyue Ju (Englewood Cliffs, New Jersey);  Huanyan Cao (Changzhou, China PRC);  Zengmin Li (Flushing, New York);  Qinglin Meng (Foster City, California);  Jia Guo (Chandler, Arizona);  Shenglong Zhang (Fort Lee, New Jersey);  Lin Yu (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Jingyue Ju (Englewood Cliffs, New Jersey);  Huanyan Cao (Changzhou, China PRC);  Zengmin Li (Flushing, New York);  Qinglin Meng (Foster City, California);  Jia Guo (Chandler, Arizona);  Shenglong Zhang (Fort Lee, New Jersey);  Lin Yu (New York, New York)
ABSTRACT This invention provides novel azido linkers for deoxynucleotide analogues having a detectable marker attached thereto.
FILED Monday, December 03, 2018
APPL NO 16/208379
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 19/06 (20130101)
C07H 19/10 (20130101)
C07H 19/14 (20130101)
C07H 19/16 (20130101)
C07H 19/20 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6869 (20130101) Original (OR) Class
C12Q 1/6869 (20130101)
C12Q 2525/301 (20130101)
C12Q 2525/301 (20130101)
C12Q 2537/157 (20130101)
C12Q 2537/157 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209367 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Yale University (New Haven, Connecticut)
ASSIGNEE(S) YALE UNIVERSITY (New Haven, Connecticut)
INVENTOR(S) Yongdeng Zhang (New Haven, Connecticut);  Joerg Bewersdorf (Guilford, Connecticut)
ABSTRACT Methods and systems for fluorescence imaging are described herein. The method can include: receiving a fluorescence signal including an excitation signal, a first emission signal for a first fluorophore having a first emission spectra, and a second emission signal for a second fluorophore having a second emission spectra; filtering the fluorescence signal to: isolate a first channel encompassing at least one of: a bandwidth of at least 1 nm within which an emission intensity of the first emission spectra is at least twice an emission intensity of the second emission spectra, a bandwidth having a rising edge of the first emission spectra; and at least 10% by height of a rising edge of the first emission spectra, and produce a channel including the fluorescence signal less the first channel; and directing the first channel and the resulting channel to different regions of one or more cameras for collecting fluorescence emissions.
FILED Monday, August 26, 2019
APPL NO 16/551192
ART UNIT 2884 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6458 (20130101) Original (OR) Class
G01N 2021/6421 (20130101)

Optical Elements, Systems, or Apparatus
G02B 21/16 (20130101)
G02B 21/0032 (20130101)
G02B 21/0072 (20130101)
G02B 21/0076 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209390 Ha et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Noel Seunghyun Ha (Los Angeles, California);  R. Michael Van Dam (Los Angeles, California);  Jimmy Ly (San Francisco, California)
ABSTRACT A volumetric microfluidic injector for capillary electrophoresis (CE) for highly repeatable sample injection has been designed and built to eliminate known injection bias in hydrodynamic injection. A defined volume from 1-10 nL or 0.1-100 nL of sample is confined in a defined region of a micro-valve PDMS microfluidic injector chip and electrophoretic potential is applied to drive sample into a separation device such as an embedded fused silica capillary for separation and detection. Using a 75 μm ID capillary, the RSD of an absorbance peak area as low as 1.32% (n=11) is obtained. As a comparison, the time-dependent injection was tested using the same chip which resulted in an inferior repeatability.
FILED Friday, October 06, 2017
APPL NO 16/339348
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/50273 (20130101)
B01L 3/502738 (20130101)
B01L 2400/0421 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/453 (20130101)
G01N 27/44743 (20130101)
G01N 27/44791 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209393 Garimella et al.
FUNDED BY
Department of Energy (DOE)
Battelle Memorial Institute (BATTELLE)
Pacific Northwest National Laboratory (PNNL)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Venkata B S Garimella (Richland, Washington);  Ahmed M. Hamid (Richland, Washington);  Yehia M. Ibrahim (West Richland, Washington);  Richard D. Smith (Richland, Washington)
ABSTRACT Methods and apparatuses for ion manipulations, including ion trapping, transfer, and mobility separations, using traveling waves (TW) formed by continuous alternating current (AC) are disclosed. An apparatus for ion manipulation includes a surface to which are coupled a first plurality of continuous electrodes and a second plurality of segmented electrodes. The second plurality of segmented electrodes is arranged in longitudinal sets between or adjacent to the first plurality of electrodes. An RF voltage applied to adjacent electrodes of the first plurality of electrodes is phase shifted by approximately 180° to confine ions within the apparatus. An AC voltage waveform applied to adjacent electrodes within a longitudinal set of the second plurality of segmented electrodes is phase shifted on the adjacent electrodes by 1°-359° to move ions longitudinally through the apparatus for separation.
FILED Monday, May 06, 2019
APPL NO 16/404472
ART UNIT 2881 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/624 (20130101) Original (OR) Class

Electric Discharge Tubes or Discharge Lamps
H01J 49/26 (20130101)
H01J 49/0027 (20130101)
H01J 49/062 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209420 Bar-Sagi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) New York University (New York, New York)
ASSIGNEE(S) NEW YORK UNIVERSITY (New York, New York)
INVENTOR(S) Dafna Bar-Sagi (Miller Place, New York);  Cosimo Commisso (New York, New York);  Rengin De Chey (New York, New York)
ABSTRACT The present invention is directed to methods of inhibiting both proliferation and survival of cancer cells and for treating a subject having cancer. The present invention is further directed to methods of diagnosing cancer in a subject and identifying cancer therapeutics.
FILED Friday, May 25, 2018
APPL NO 15/990030
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/192 (20130101)
A61K 31/352 (20130101)
A61K 31/366 (20130101)
A61K 31/407 (20130101)
A61K 31/435 (20130101)
A61K 31/685 (20130101)
A61K 31/4178 (20130101)
A61K 31/4965 (20130101)
A61K 31/5377 (20130101)
A61K 38/00 (20130101)
A61K 45/06 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/10 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/574 (20130101)
G01N 33/5005 (20130101) Original (OR) Class
G01N 33/5011 (20130101)
G01N 2800/7028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209426 Gendelman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Institute on Drug Abuse (NIDA)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Board of the Regents of the University of Nebraska (Lincoln, Nebraska)
ASSIGNEE(S) BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska)
INVENTOR(S) Howard E. Gendelman (Omaha, Nebraska);  R. Lee Mosley (Omaha, Nebraska);  Jessica A. Saunders (Stanford, California)
ABSTRACT Methods and compositions for detecting and diagnosing Parkinson's disease are disclosed.
FILED Friday, December 07, 2012
APPL NO 14/357682
ART UNIT 1699 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/53 (20130101)
G01N 33/6896 (20130101)
G01N 33/54306 (20130101) Original (OR) Class
G01N 2800/2835 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209427 Kamei et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Daniel T. Kamei (Monterey Park, California);  Maie A. ST John (Los Angeles, California);  Zachary D. Taylor (Los Angeles, California);  Daniel W. Bradbury (Los Angeles, California);  Ashley E. Kita (Los Angeles, California)
ABSTRACT Devices and methods are provided for the detection of CSF in a biological sample. In certain embodiments the device is a lateral flow device comprising: a porous substrate; a sample addition zone disposed on or in said porous substrate; a detection zone disposed on or in said porous substrate where said detection zone comprises at least a first test line (T1) and a second test line (T2) each test line comprising binding moieties that bind a complex formed between beta-trace protein (betaTP) and an indicator attached to a betaTP binding molecule; wherein said porous substrate defines a flow path through which a sample applied to the sample addition zone flows under capillary action away from said sample addition zone into said detection zone.
FILED Monday, March 26, 2018
APPL NO 16/498312
ART UNIT 1799 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5023 (20130101)
B01L 2400/0406 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/54386 (20130101) Original (OR) Class
G01N 2333/99 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209433 Campbell et al.
FUNDED BY
Department of Health and Human Services (HHS)
Assistant Secretary for Preparedness and Response (ASPR)
APPLICANT(S) Becton, Dickinson and Company (Franklin Lakes, New Jersey)
ASSIGNEE(S) Becton, Dickinson and Company (Franklin Lakes, New Jersey)
INVENTOR(S) Robert Campbell (Bullock, North Carolina);  Kevin G. Dolan (Holly Springs, North Carolina);  Eric Fallows (Apex, North Carolina);  Randal A. Hoke (Cary, North Carolina);  Ross Jacobson (Hillsborough, North Carolina);  J. Bruce Pitner (Durham, North Carolina);  Glenn P. Vonk (Fuquay Varina, North Carolina);  Rajashaker Kache (Cary, North Carolina);  Upma Gulati (Cary, North Carolina);  Herman D. Himel, IV (Cary, North Carolina);  Rosemary B. Evans-Storms (Durham, North Carolina)
ABSTRACT Some embodiments provided herein relate to combined assays. In some embodiments, an assay for identifying influenza type A or influenza type B is combined with an assay for determining the sensitivity of an influenza neuraminidase to an antiviral drug.
FILED Monday, April 15, 2019
APPL NO 16/384020
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 15/203 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56983 (20130101) Original (OR) Class
G01N 2333/11 (20130101)
G01N 2333/924 (20130101)
G01N 2500/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209434 Leung et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) National Jewish Health (Denver, Colorado)
ASSIGNEE(S) National Jewish Health (Denver, Colorado)
INVENTOR(S) Donald Y. M. Leung (Denver, Colorado);  Elena Goleva (Denver, Colorado);  Lingbo Li (Denver, Colorado)
ABSTRACT The present invention is directed toward novel methods to identify as well as to treat a subject having an inflammatory disease resistant to corticosteroids.
FILED Tuesday, July 10, 2018
APPL NO 16/031633
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 16/40 (20130101)
C07K 2317/76 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1137 (20130101)
C12N 2310/14 (20130101)
C12N 2320/30 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/485 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/573 (20130101) Original (OR) Class
G01N 2333/91205 (20130101)
G01N 2333/91215 (20130101)
G01N 2800/52 (20130101)
G01N 2800/122 (20130101)
G01N 2800/7095 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209440 Kuchroo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Institute of Allergy and Infectious Diseases (NIAID)
NIH Office of the Director (NIHOD)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts);  THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts);  PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts);  MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
ASSIGNEE(S)
INVENTOR(S) Vijay Kuchroo (Newton, Massachusetts);  Aviv Regev (Cambridge, Massachusetts);  Jellert Gaublomme (Maasmechelen, Belgium);  Youjin Lee (San Francisco, California);  Alexander K. Shalek (Lexington, Massachusetts);  Chao Wang (Cambridge, Massachusetts);  Nir Yosef (Richmond, California);  Hongkun Park (Cambridge, Massachusetts)
ABSTRACT This invention relates generally to compositions and methods for identifying the regulatory network that modulates, controls or otherwise influences T cell balance, for example, Th17 cell differentiation, maintenance and/or function, as well compositions and methods for exploiting the regulatory network that modulates, controls or otherwise influences T cell balance in a variety of therapeutic and/or diagnostic indications. This invention also relates generally to identifying and exploiting target genes and/or target gene products that modulate, control or otherwise influence T cell balance in a variety of therapeutic and/or diagnostic indications.
FILED Wednesday, August 24, 2016
APPL NO 15/245748
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 48/00 (20130101)

Peptides
C07K 16/2866 (20130101)
C07K 16/2896 (20130101)
C07K 2317/21 (20130101)
C07K 2317/24 (20130101)
C07K 2317/75 (20130101)
C07K 2317/76 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/68 (20130101)
C12N 15/86 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101)
C12Q 2600/112 (20130101)
C12Q 2600/118 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6863 (20130101) Original (OR) Class
G01N 2800/50 (20130101)
G01N 2800/52 (20130101)
G01N 2800/56 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209454 Fu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Kevin Fu (Ann Arbor, Michigan);  Peter Honeyman (Ann Arbor, Michigan);  Timothy Trippel (Ann Arbor, Michigan);  Ofir Weisse (Ann Arbor, Michigan)
ABSTRACT Cyber-physical systems depend on sensors to make automated decisions. Resonant acoustic injection attacks are already known to cause malfunctions by disabling MEMS-based gyroscopes. However, an open question remains on how to move beyond denial of service attacks to achieve full adversarial control of sensor outputs. This work investigates how analog acoustic injection attacks can damage the digital integrity of a popular type of sensor: the capacitive MEMS accelerometer. Spoofing such sensors with intentional acoustic interference enables an out-of-spec pathway for attackers to deliver chosen digital values to microprocessors and embedded systems that blindly trust the unvalidated integrity of sensor outputs. Two software-based solutions are presented for mitigating acoustic interference with output of a MEMS accelerometer and other types of motion sensors.
FILED Friday, May 19, 2017
APPL NO 16/303495
ART UNIT 2862 — Printing/Measuring and Testing
CURRENT CPC
Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement
G01P 13/00 (20130101) Original (OR) Class
G01P 15/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209776 Brooker et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) CellOptic, Inc. (Rockville, Maryland)
ASSIGNEE(S) CELLOPTIC, INC. (Rockville, Maryland)
INVENTOR(S) Gary Brooker (Rockville, Maryland);  Nisan Siegel (Silver Spring, Maryland)
ABSTRACT Techniques to improve image quality in holography utilizing lenses made from materials with non-quantized anisotropic electromagnetic properties, such as birefringent materials, to advantageously split an incoming beam of light into two coincident beams with different focal lengths that interfere with one another and thus create holograms free of electro-optical or pixelated devices are disclosed for microscopy and other applications. The use of thin birefringent lenses and single crystal alpha-BBO lenses are introduced. Corresponding systems, methods and apparatuses are described.
FILED Thursday, March 12, 2020
APPL NO 16/816949
ART UNIT 2872 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 3/13 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/02 (20130101)
G02B 3/08 (20130101)
G02B 5/3016 (20130101)
G02B 5/3083 (20130101)
G02B 21/0056 (20130101)
G02B 21/0068 (20130101)

Holographic Processes or Apparatus
G03H 1/0005 (20130101)
G03H 1/06 (20130101)
G03H 1/041 (20130101) Original (OR) Class
G03H 1/0443 (20130101)
G03H 1/0866 (20130101)
G03H 2001/005 (20130101)
G03H 2001/0447 (20130101)
G03H 2001/0452 (20130101)
G03H 2222/24 (20130101)
G03H 2223/17 (20130101)
G03H 2223/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11210967 Kofler
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida)
ASSIGNEE(S) Florida State University Research Foundation, INC. (Tallahassee, Florida)
INVENTOR(S) Michael J. Kofler (Tallahassee, Florida)
ABSTRACT Various embodiments are directed to a central executive training (CET) platform that targets central executive processes, rather than short term memory. Central executive deficits have been linked experimentally and developmentally with Attention Deficit Hyperactivity Disorder (ADHD) symptoms and impairments. Unfortunately, substantial evidence indicates that conventional working memory training programs fail to improve these symptoms and impairments. This discrepancy may reflect insufficient targeting, as extant protocols focus on short term memory and do not adequately engage the specific central executive components linked with the disorder's behavioral and functional impairments.
FILED Wednesday, March 28, 2018
APPL NO 15/938018
ART UNIT 3715 — Amusement and Education Devices
CURRENT CPC
Card, Board, or Roulette Games; Indoor Games Using Small Moving Playing Bodies; Video Games; Games Not Otherwise Provided for
A63F 13/67 (20140902)
A63F 13/80 (20140902)

Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 5/06 (20130101)
G09B 19/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11211168 Mohr et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) David C. Mohr (Evanston, Illinois);  Christopher Karr (Chicago, Illinois)
ABSTRACT Disclosed is an intelligent recommendation system for identifying and/or providing personalized one or more independent applications and/or healthcare related media content (e.g., multimedia content and applications involved in healthcare or the treatment of various health conditions of a user) to a plurality of user devices and/or client devices.
FILED Wednesday, July 19, 2017
APPL NO 15/654245
ART UNIT 3686 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC
Electric Digital Data Processing
G06F 3/048 (20130101)

Computer Systems Based on Specific Computational Models
G06N 5/02 (20130101)
G06N 20/00 (20190101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 50/30 (20180101) Original (OR) Class

Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/22 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 11206978 Hu et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Juejun Hu (Newton, Massachusetts);  Tian Gu (Fairfax, Virginia);  Mikhail Shalaginov (Somerville, Massachusetts);  Fan Yang (Cambridge, Massachusetts)
ABSTRACT Meta-lens based ocular imaging, near-eye display, and eye-tracking systems are described. The systems can include a single focusing optic and an integrated circuit that provides illumination light and includes an imaging array. The focusing optic includes meta-atoms formed on a substrate. The systems may have no moving parts and achieve imaging or image-projection fields-of-view approaching or exceeding 180 degrees. Because of their low part count, the systems can be robust and have a very small form factor.
FILED Monday, February 01, 2021
APPL NO 17/164425
ART UNIT 2872 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 3/12 (20130101)
A61B 3/14 (20130101) Original (OR) Class
A61B 3/113 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/002 (20130101)
G02B 27/0093 (20130101)
G02B 27/0172 (20130101)
G02B 2027/0123 (20130101)
G02B 2027/0147 (20130101)

Electric Digital Data Processing
G06F 3/013 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207227 Cable et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
U.S. Air Force
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Cornerstone Research Group, Inc. (Miamisburg, Ohio)
ASSIGNEE(S) Cornerstone Research Group, Inc. (Miamisburg, Ohio)
INVENTOR(S) Kristin M. Cable (Dayton, Ohio);  Brian R. Pleiman (Dayton, Ohio);  Joshua E. Nieman (Centerville, Ohio)
ABSTRACT Mattresses for human stabilization may include a mass of foam material. A cover including a fabric material may at least partially surrounding the mass of foam material. Head blocks including a foam material may be located proximate to one end of the mattress. The fabric material of the cover may at least partially cover the head blocks, and the head blocks may be foldable relative to the mass of foam material to enable the head blocks to be positioned against lateral sides of a person's head. Human stabilization platforms may include a litter having a surface sized and shaped to support a person thereabove. Straps may be configured to restrain a person's head, the straps having releasable connectors at ends thereof. A track may be located on the surface of the litter, and may be configured to receive the connectors to affix the straps to the litter.
FILED Friday, May 15, 2020
APPL NO 16/875745
ART UNIT 3673 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Chairs; Sofas; Beds
A47C 27/14 (20130101)

Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 5/3769 (20130101)
A61F 5/3776 (20130101)
A61F 5/3784 (20130101)

Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices
A61G 1/044 (20130101) Original (OR) Class
A61G 1/048 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207395 Eappen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Congressionally Directed Medical Research Programs (CDMRP)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Sanaria Inc. (Rockville, Maryland)
ASSIGNEE(S) Sanaria Inc. (Rockville, Maryland)
INVENTOR(S) Abraham G. Eappen (Ellicott City, Maryland);  Stephen L. Hoffman (Gaithersburg, Maryland)
ABSTRACT The application is directed to in vitro-reared Plasmodium sporozoites of human host range wherein sporogony from gametocyte stage to sporozoite stage is external to mosquitoes, and methods of producing the same. Provided herein are in vitro-reared infectious Plasmodium sporozoites (SPZ) of human host range, particularly P. falciparum, P. vivax, P. ovale, P. malariae, and P. knowlesi, wherein sporogony from gametocyte stage to sporozoite stage is external to mosquitoes, and methods of producing the same.
FILED Thursday, September 05, 2019
APPL NO 16/561814
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/015 (20130101) Original (OR) Class
A61K 2039/52 (20130101)
A61K 2039/522 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/10 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207398 Ciaramella et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) ModernaTX, Inc. (Cambridge, Massachusetts)
ASSIGNEE(S) ModernaTX, Inc. (Cambridge, Massachusetts)
INVENTOR(S) Giuseppe Ciaramella (Sudbury, Massachusetts);  Sunny Himansu (Winchester, Massachusetts)
ABSTRACT Provided herein, in some embodiments, are Zika virus RNA vaccines and methods of producing an antigen-specific immune response in a subject.
FILED Tuesday, April 14, 2020
APPL NO 16/848318
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101) Original (OR) Class
A61K 2039/53 (20130101)
A61K 2039/54 (20130101)
A61K 2039/545 (20130101)
A61K 2039/575 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2770/24134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207489 Patel et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Aashish N. Patel (Cordova, Tennessee);  Praveen K. Pilly (West Hills, California)
ABSTRACT Described is an improved brain-machine interface including a neural interface and a controllable device in communication with the neural interface. The neural interface includes a neural device with one or more sensors for collecting signals of interest and one or more processors for conditioning the signals of interest, extracting salient neural features from and decoding the conditioned signals of interest, and generating a control command for the controllable device. The controllable device performs one or more operations according to the control command, and the neural device administers neuromodulation stimulation to reinforce operation of the controllable device.
FILED Thursday, May 30, 2019
APPL NO 16/426198
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/291 (20210101)

Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/72 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 21/00 (20130101) Original (OR) Class
A61M 2021/0027 (20130101)
A61M 2021/0044 (20130101)
A61M 2021/0055 (20130101)
A61M 2205/52 (20130101)
A61M 2205/502 (20130101)
A61M 2205/3313 (20130101)
A61M 2230/10 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0456 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207836 Ramos et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems (SPAWAR)
National Science Foundation (NSF)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Javier E. Ramos (Brookline, Massachusetts);  Pitchaya Sitthi-Amorn (Cambridge, Massachusetts);  Wojciech Matusik (Lexington, Massachusetts);  Yuwang Wang (Beijing, China PRC)
ABSTRACT The present application relates generally to systems and methods for using machine vision to provide information on one or more aspects of an additive fabrication device, such as calibration parameters and/or an object formed by the device or in the process of being formed by the device. According to some aspects, a method is provided for calibrating an additive fabrication device. According to some aspects, a method is provided for assessing at least a portion of an object formed using an additive fabrication device. According to some aspects, a method is provided for fabricating a second object in contact with a first object using an additive fabrication device. According to some aspects, an additive fabrication device configured to perform one or more of the above methods may be provided.
FILED Tuesday, July 30, 2019
APPL NO 16/526068
ART UNIT 1747 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/106 (20170801)
B29C 64/112 (20170801)
B29C 64/386 (20170801) Original (OR) Class
B29C 64/393 (20170801)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
B33Y 50/02 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208180 Ruffa
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Secretary of the Navy (SECNAV)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (, None)
INVENTOR(S) Anthony A Ruffa (Hope Valley, Rhode Island)
ABSTRACT A system is provided to compensate for heave of a vessel in which the compensation system has a first panel with a first magnetic field having magnetic flux disposed in a first direction and a second panel parallel to the first panel. The second panel has a second magnetic field having magnetic flux disposed in a second direction with the first magnetic field parallel to the second magnetic field. A conducting loop is located between the first panel and the second panel. The conducting loop is attachable to a cable connected to a load suspended in water. Compensating force generated by the first magnetic field and the second magnetic field transfers to the cable to compensate for heaving motion of the vessel and stabilize the cable-connected load in the water.
FILED Tuesday, July 14, 2020
APPL NO 16/928041
ART UNIT 3617 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Ships or Other Waterborne Vessels; Equipment for Shipping
B63B 21/56 (20130101)
B63B 39/00 (20130101) Original (OR) Class

Capstans; Winches; Tackles, e.g Pulley Blocks; Hoists
B66D 1/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208420 Sadler et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Secretary of the Army (SECARMY)
APPLICANT(S) DREXEL UNIVERSITY (Philadelphia, Pennsylvania);  The Government of the United States of America as Represented by the Secretary of the Army (Adelphi, Maryland)
ASSIGNEE(S) Drexel University (Philadelphia, Pennsylvania);  THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Washington, District of Columbia)
INVENTOR(S) Joshua Matthew Sadler (Middle River, Maryland);  John Joseph La Scala (Wilmington, Delaware);  Giuseppe R. Palmese (Hainesport, New Jersey)
ABSTRACT This invention outlines a method for synthesizing a blended resin system in a one pot reaction that may utilize, for example, bio-based anhydrosugars such as isosorbide as a principle component to produce isosorbide dimethacrylate and other monomeric materials for thermosetting applications. This invention establishes a one-pot procedure for reacting a hydroxy group containing compound with methacrylic anhydride in the first step and using the by-product methacrylic acid to react with glycidyl ethers to form additional methacrylate compounds in the second step. This methodology can be formulated to produce a wide array of resin systems that have controlled ratios of hydroxy group containing compound/crosslinker/reactive diluent. Additionally, the novel resin systems may be partially to fully biobased, promoting global sustainability and reducing costs, and when free radically polymerized have properties that meet or exceed their petroleum derived counterparts.
FILED Thursday, November 16, 2017
APPL NO 16/462741
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Heterocyclic Compounds
C07D 493/04 (20130101) Original (OR) Class

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 59/42 (20130101)
C08G 59/1466 (20130101)
C08G 59/4238 (20130101)

Compositions of Macromolecular Compounds
C08L 33/08 (20130101)
C08L 33/10 (20130101)
C08L 63/00 (20130101)
C08L 2312/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208478 Altieri
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Wistar Institute of Anatomy and Biology (Philadelphia, Pennsylvania)
ASSIGNEE(S) THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (Philadelphia, Pennsylvania)
INVENTOR(S) Dario C. Altieri (Philadelphia, Pennsylvania)
ABSTRACT Therapeutic treatments of a tumor expressing pT346 PDK1, including glioma expressing pT346 PDK1, are disclosed.
FILED Friday, August 04, 2017
APPL NO 16/323648
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/19 (20130101)
A61K 31/19 (20130101)
A61K 31/20 (20130101)
A61K 31/20 (20130101)
A61K 31/167 (20130101)
A61K 31/167 (20130101)
A61K 31/385 (20130101)
A61K 31/385 (20130101)
A61K 31/444 (20130101)
A61K 31/444 (20130101)
A61K 31/496 (20130101)
A61K 31/496 (20130101)
A61K 31/519 (20130101)
A61K 31/519 (20130101)
A61K 31/4439 (20130101)
A61K 31/4439 (20130101)
A61K 31/5383 (20130101)
A61K 31/5383 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 16/28 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/573 (20130101)
G01N 33/574 (20130101)
G01N 33/57407 (20130101)
G01N 2333/91205 (20130101)
G01N 2440/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208571 Wang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) University of Maryland, College Park (College Park, Maryland)
ASSIGNEE(S) UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland)
INVENTOR(S) YuHuang Wang (Laurel, Maryland);  Peng Wang (Rockville, Maryland);  Mijin Kim (New York, New York);  Chiyu Zhang (Berwyn Heights, Maryland)
ABSTRACT A method termed “superacid-surfactant exchange” (S2E) for the dispersion of carbon nanomaterials in aqueous solutions. This S2E method enables nondestructive dispersion of carbon nanomaterials (including single-walled carbon nanotubes, double-walled carbon nanotubes, multi-wall carbon nanotubes, and graphene) at rapidly and at large scale in aqueous solution without a requirement for expensive or complicated equipment. Dispersed carbon nanotubes obtained from this method feature long length, low defect density, high electrical conductivity, and in the case of semiconducting single-walled carbon nanotubes, bright photoluminescence in the near-infrared.
FILED Thursday, August 08, 2019
APPL NO 16/536166
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 32/19 (20170801)
C01B 32/21 (20170801)
C01B 32/156 (20170801)
C01B 32/159 (20170801)
C01B 32/172 (20170801)
C01B 32/174 (20170801)
C01B 32/194 (20170801)
C01B 2202/02 (20130101)
C01B 2202/04 (20130101)
C01B 2202/06 (20130101)
C01B 2202/22 (20130101)
C01B 2202/28 (20130101)
C01B 2202/34 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 11/037 (20130101)
C09D 11/52 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208630 Clement et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S) Nathalie Clement (Gainesville, Florida);  Barry John Byrne (Gainesville, Florida);  Laura A. Small (Gainesville, Florida)
ABSTRACT Provided herein are methods of improving rAAV production in cells, the method comprising increasing the salt concentration in the media in which the cells are infected or transfected, cultured, or in which they produce AAV. Aspects of the disclosure relate to improved methods of rAAV production by co-infecting suspension adapted cells (e.g., suspension adapted HEK293 cells) with viruses that encode one or more AAV components for producing rAAV particles within the suspension adapted cells.
FILED Friday, December 23, 2016
APPL NO 16/065546
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101) Original (OR) Class
C12N 15/86 (20130101)
C12N 2710/16644 (20130101)
C12N 2750/14151 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208676 Xuan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Feng Xuan (Boston, Massachusetts);  Peng Yin (Brookline, Massachusetts);  Mingjie Dai (Brookline, Massachusetts);  Xi Chen (West Newton, Massachusetts)
ABSTRACT The present disclosure provides, in some embodiments, methods and compositions for single-molecule detection.
FILED Friday, May 26, 2017
APPL NO 16/304323
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6804 (20130101) Original (OR) Class
C12Q 1/6804 (20130101)
C12Q 2525/186 (20130101)
C12Q 2525/301 (20130101)
C12Q 2531/119 (20130101)
C12Q 2565/514 (20130101)

Combinatorial Chemistry; Libraries, e.g Chemical Libraries
C40B 70/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208954 Loebig et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
United States Air Force (USAF)
APPLICANT(S) Rolls-Royce Corporation (Indianapolis, Indiana);  Rolls-Royce North American Technologies, Inc. (Indianapolis, Indiana)
ASSIGNEE(S) Rolls-Royce Corporation (Indianapolis, Indiana);  Rolls-Royce North American Technologies, Inc. (Indianapolis, Indiana)
INVENTOR(S) James C. Loebig (Greenwood, Indiana);  Emil R. Dejulio (Columbus, Indiana)
ABSTRACT A microchannel heat exchanger (MCHX) includes an air-passage layer including a plurality of air-passage microchannels, a working fluid layer including a plurality of working fluid microchannels, and a sealing layer coupled to the working fluid layer to provide a working/sealing layer set. The working/sealing layer set includes an arrangement of raised pedestals. The raised pedestals may extend from the working fluid layer to the sealing layer and contact the sealing layer.
FILED Wednesday, June 26, 2019
APPL NO 16/453061
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 3/04 (20130101)
F02C 7/18 (20130101) Original (OR) Class
F02C 7/143 (20130101)

Jet-propulsion Plants
F02K 3/115 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2210/13 (20130101)
F05D 2220/62 (20130101)
F05D 2220/72 (20130101)
F05D 2230/11 (20130101)
F05D 2260/204 (20130101)
F05D 2260/205 (20130101)
F05D 2260/207 (20130101)

Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 9/0012 (20130101)
F28D 9/0031 (20130101)
F28D 9/0037 (20130101)
F28D 2021/0026 (20130101)

Details of Heat-exchange and Heat-transfer Apparatus, of General Application
F28F 3/048 (20130101)
F28F 9/026 (20130101)
F28F 2260/00 (20130101)
F28F 2275/00 (20130101)
F28F 2275/061 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208998 Hosoi et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Anette E. Hosoi (Cambridge, Massachusetts);  Youzhi Liang (Cambridge, Massachusetts);  Irmgard Bischofberger (Somerville, Massachusetts);  Yongbin Sun (Malden, Massachusetts);  Qing Zhang (Cambridge, Massachusetts);  Tianshi Fang (Cambridge, Massachusetts)
ABSTRACT A microfluidic pumping system configured to prevent backflow from an outlet of the system toward an inlet of the system. The microfluidic pumping system comprising a gear housing that has an inlet and an outlet and that houses a drive gear, an idler gear and a drive shaft. The system further includes a front end plate that is coupled to a first surface of the gear housing and a rear end plate that is coupled to a second, different surface of the gear housing. Also coupled to the gear housing is a first and second Halbach magnet arrays that is disposed between the front end plate and the rear end plate. The first and second Halbach magnet arrays include one or more solenoids and the first Halbach magnet array is disposed proximate to the drive gear and the second Halbach magnet array is disposed proximate to the idler gear.
FILED Thursday, June 27, 2019
APPL NO 16/454405
ART UNIT 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Rotary-piston, or Oscillating-piston, Positive-displacement Machines for Liquids; Rotary-piston, or Oscillating-piston, Positive-displacement Pumps
F04C 2/18 (20130101) Original (OR) Class
F04C 13/001 (20130101)
F04C 15/0026 (20130101)
F04C 27/00 (20130101)

Indexing Scheme Relating to Materials, Material Properties or Material Characteristics for Machines, Engines or Pumps Other Than Non-positive-displacement Machines or Engines
F05C 2251/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209022 Filardo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Pliant Energy Systems LLC (Brooklyn, New York)
ASSIGNEE(S) Pliant Energy Systems LLC (Brooklyn, New York)
INVENTOR(S) Benjamin Pietro Filardo (New York, New York);  Daniel S. Zimmerman (Brooklyn, New York);  Michael I. Weaker (Brooklyn, New York)
ABSTRACT The VEHICLE WITH TRAVELING WAVE THRUST MODULE APPARATUSES, METHODS AND SYSTEMS include force or forces applied to an arc-like flexible sheet-like material to create a deformed crenated strip fin with strained-deformations. The strained-deformations take on a sinusoid-like form that express the internal energy state of the flexible sheet-like material after it has been configured into a crenated strip fin. After being incorporated into a mechanism with couplings that prevent the crenated strip fin from returning to its un-strained state, the strained-deformations persist. Actuators may be used to sequentially rotate vertebrae attached to the fins causing the travel of sinusoid-like deformations along the fins. The fin, fin actuator or actuators, power source and central controller may be incorporated into a thrust module. Two thrust modules couple to each other via roll actuators and flexible coupling members may form a vehicle with exceptional maneuverability.
FILED Monday, December 30, 2019
APPL NO 16/730649
ART UNIT 2832 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Marine Propulsion or Steering
B63H 1/37 (20130101)

Machines or Engines for Liquids
F03B 5/00 (20130101)

Wind Motors
F03D 5/06 (20130101)

Non-positive-displacement Pumps
F04D 33/00 (20130101) Original (OR) Class

Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G
F05B 2240/40 (20130101)
F05B 2240/97 (20130101)
F05B 2240/311 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209255 Sequeira et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Secretary of the Army (SECARMY)
APPLICANT(S) U.S. Government as Represented by the Secretary of the Army (Dover, New Jersey)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) John Sequeira (Jersey City, New Jersey);  Sean Swaszek (Denville, New Jersey)
ABSTRACT An improved process provides high-density pre-form billets that meet dimensional limitations required for case-load tooling. Previous isostatic fill procedures were improved in two ways to accommodate varying bulk densities or powder compositions. First, during the isostatic fill procedure, the powder fill is subject to both a high frequency vibration and a high amplitude, low frequency impulse. The combination of these two inputs is critical to ensure polymer bonded explosives pack to consistent densities. Second, unlike in conventional practices, the fill rate is kept constant throughout the entire fill process and the mold is completely filled by the time the required powder mass has been dispensed.
FILED Thursday, September 03, 2020
APPL NO 17/010933
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Machines, Apparatus or Devices For, or Methods Of, Packaging Articles or Materials; Unpacking
B65B 3/34 (20130101)

Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 33/001 (20130101)
F42B 33/02 (20130101)
F42B 33/0257 (20130101) Original (OR) Class
F42B 33/0285 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209369 Wilson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Secretary of the Army (SECARMY)
APPLICANT(S) United States of America as Represented by The Secretary of the Army (Alexandria, Virginia)
ASSIGNEE(S) UNITED STATES of AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia)
INVENTOR(S) Rebekah C Wilson (Mahomet, Illinois);  Benjamin C Masters (Urbana, Illinois)
ABSTRACT Disclosed are methods that, by not physically touching a material being measured, can measure the material's differential response quite accurately. A collimated light shines on the material under test, is reflected off it, and is then captured by a device that records the position where the reflected light is captured. This process is done both before and after the material is processed in some way (e.g., by applying a coat of paint). The change in position where the reflected light is captured is used in calculating the deflection of the material as induced by the process. This measured induced deflection is then used to accurately determinate the stress introduced into the material by the process. Other characteristics of the material under test, such as aspects of the material composition of a bi-metallic strip, for example, may also be determined from a deflection measurement.
FILED Monday, September 30, 2019
APPL NO 16/588185
ART UNIT 2886 — Optics
CURRENT CPC
Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 1/24 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/86 (20130101) Original (OR) Class
G01N 21/8422 (20130101)
G01N 2021/8438 (20130101)
G01N 2021/8636 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209412 Hasty et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
United States Army (USA)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jeff Hasty (Encinitas, California);  Leo Alexander Baumgart (San Diego, California);  Scott Cookson (Encinitas, California);  Michael Ferry (San Diego, California);  Garrett Graham (San Diego, California);  Ramon Huerta (San Diego, California);  Ryan Johnson (San Diego, California);  Lev Tsimring (San Diego, California)
ABSTRACT Provided are a microfluidic biosensors that are suitable for continuously monitoring toxin levels in water supplies.
FILED Friday, February 12, 2016
APPL NO 15/551124
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/50273 (20130101)
B01L 2300/023 (20130101)
B01L 2300/0654 (20130101)
B01L 2400/0481 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 23/16 (20130101)
C12M 41/00 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/02 (20130101)
C12Q 1/6897 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/1813 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209429 Kidwell
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Secretary of the Navy (SECNAV)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) David A. Kidwell (Alexandria, Virginia)
ABSTRACT The present invention provides a method for increasing the sensitivity of LFIAs by using palladium nanoparticles, selecting appropriate dye chemistries, and improving the timing of the development chemistry. In the presence of a palladium nanoparticle, three reagents interact with a catalytic label to form a colored dye. The three reagents include a hydrogen peroxide source, a color developer (a substituted para-phenylenediamine), and a color coupler (e.g. a napthol or a phenol). The timing of the development chemistry is improved by any combination of using a reducing agent, delaying hydrogen peroxide application by diffusion, using dissolving materials as a time delay, using serpentine flow, and separating the color coupler and the color developer on the strip.
FILED Thursday, May 02, 2019
APPL NO 16/401411
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 99/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/78 (20130101)
G01N 33/531 (20130101)
G01N 33/533 (20130101)
G01N 33/558 (20130101)
G01N 33/583 (20130101)
G01N 33/587 (20130101)
G01N 33/5306 (20130101)
G01N 33/54346 (20130101)
G01N 33/54393 (20130101) Original (OR) Class
G01N 2021/7756 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209432 Cartwright et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Space and Naval Warfare Systems (SPAWAR)
APPLICANT(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S) Mark J. Cartwright (West Newton, Massachusetts);  Nazita Gamini (Somerville, Massachusetts);  Donald E. Ingber (Boston, Massachusetts);  Martin Rottman (La Celle-Saint-Cloud, France);  Michael Super (Lexington, Massachusetts);  Julie A. Tomolonis (Houston, Texas);  Karen A. Sinclair (Cambridge, Massachusetts)
ABSTRACT The disclosure provides methods, compositions, and kits for enhanced detection of microbes in samples and monitoring of antimicrobial activity in a subject.
FILED Thursday, June 11, 2020
APPL NO 16/898754
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/18 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5695 (20130101)
G01N 33/56911 (20130101) Original (OR) Class
G01N 33/56961 (20130101)
G01N 2333/4724 (20130101)
G01N 2400/00 (20130101)
G01N 2800/26 (20130101)
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209571 Crocker et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Secretary of the Navy (SECNAV)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (, None)
INVENTOR(S) Steven E Crocker (Bristol, Rhode Island);  Ronald R Smalley (North Kingstown, Rhode Island)
ABSTRACT A method is provided to measure a modulus of complex sensitivity of hydrophone data channels using a quasi-diffuse sound field. In the method, a radiation pattern representing shallow water sources directs to a location as a direct acoustic path and sound reflects to the location from the water bottom as a reflected acoustic path. At least one hydrophone receives the sounds at the location as acoustic signals with an acoustic intensity being the sound intensities along the acoustic paths. The sound intensity at the hydrophones also relates to a zenith angle and a bottom intensity reflection coefficient. The modulus of the frequency dependent sensitivity of the hydrophone is computed from measurements of the voltage output and voltages of reference hydrophones with the sound intensity as factor and with uncertainty reduced by averaging hydrophone sensitivities.
FILED Tuesday, September 25, 2018
APPL NO 16/140642
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags
G01V 1/186 (20130101)
G01V 13/00 (20130101) Original (OR) Class

Transmission
H04B 1/0475 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209675 Manzur et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Secretary of the Navy (SECNAV)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (, None)
INVENTOR(S) Tariq Manzur (Lincoln, Rhode Island);  Yifei Li (East Walpole, Massachusetts)
ABSTRACT An optically biased photonic link receives a radio frequency (RF) signal and includes a signal laser joined to an optical intensity modulator. A low noise amplifier receives the RF signal and provides an amplified signal to the modulator. The modulator converts the signal into an optical signal. The amplifier and modulator are powered by a photovoltaic array. The array receives power from a remotely located power laser. The optical signal is received by a link receiver which provides an analysis signal and an output signal. A bias logic circuit uses the analysis signal to provide an optical bias signal to an optical detector joined to modulator. The optical detector provides a responsive bias voltage to the modulator.
FILED Thursday, July 02, 2020
APPL NO 16/919253
ART UNIT 2636 — Optical Communications
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/0123 (20130101) Original (OR) Class

Transmission
H04B 10/54 (20130101)
H04B 10/66 (20130101)
H04B 10/505 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209716 Valentine et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) Vanderbuilt University (Nashville, Tennessee)
INVENTOR(S) Jason G. Valentine (Nashville, Tennessee);  Richard F. Haglund (Nashville, Tennessee);  Zhihua Zhu (Nashville, Tennessee);  Austin Howes (Nashville, Tennessee)
ABSTRACT According to some aspects, a transmissive and all-dielectric optical component/limiter with great cutoff efficiency using Vanadium Dioxide (VO2) as the active component is disclosed. In some embodiments, Vanadium dioxide is used for an optical limiter due to the large contrast in optical constants upon undergoing the semiconductor to metal phase transition. When triggered optically, this transition occurs within 60 fs, making the device suitable for an ultrafast laser environment. In addition, the phase transition threshold is tunable by applying stress or doping; therefore, the device cutoff intensity can be adjusted to fulfill specific requirements.
FILED Friday, October 04, 2019
APPL NO 16/593551
ART UNIT 2874 — Optics
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/3501 (20130101)
G02F 1/3507 (20210101)
G02F 1/3509 (20210101)
G02F 1/3523 (20130101) Original (OR) Class
G02F 1/3556 (20130101)
G02F 1/3558 (20130101)
G02F 2202/30 (20130101)
G02F 2203/15 (20130101)
G02F 2203/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11210441 Chappell et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Secretary of the Army (SECARMY)
APPLICANT(S) United States of America as Represented by The Secretary of The Army (Alexandria, Virginia)
ASSIGNEE(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia)
INVENTOR(S) Mark A Chappell (Vicksburg, Mississippi);  Michael L Mayo (Vicksburg, Mississippi);  Jonathon A. Brame (Vicksburg, Mississippi);  Matthew C. Brondum (Vicksburg, Mississippi)
ABSTRACT The present invention is a computer modeling system for creating a comprehensive environmental impact model. The system performs a series of novel functions to reflect the impact of multiple emissions on all species of interest within an environment at designated concentration levels. The system can be further utilized as a repository to update environmental data received from scientific researchers and to update existing models accordingly. The system integrates new data and updates calculations to create increasingly complex, comprehensive and reliable predictive models for users, which include US and foreign entities charged with developing emissions standards.
FILED Monday, January 13, 2020
APPL NO 16/741705
ART UNIT 2127 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 17/18 (20130101)
G06F 30/20 (20200101) Original (OR) Class
G06F 2111/10 (20200101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/063 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11210570 Shen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
United States Air Force (USAF)
APPLICANT(S) Intelligent Fusion Technology, Inc (Germantown, Maryland)
ASSIGNEE(S) INTELLIGENT FUSION TECHNOLOGY, INC. (Germantown, Maryland)
INVENTOR(S) Dan Shen (Germantown, Maryland);  Peter Zulch (Rome, New York);  Marcello Disasio (Rome, New York);  Erik Blasch (Arlington, Virginia);  Genshe Chen (Germantown, Maryland);  Zhonghai Wang (Germantown, Maryland);  Jingyang Lu (Germantown, Maryland)
ABSTRACT The present disclosure provides a method for joint manifold learning based heterogenous sensor data fusion, comprising: obtaining learning heterogeneous sensor data from a plurality sensors to form a joint manifold, wherein the plurality sensors include different types of sensors that detect different characteristics of targeting objects; performing, using a hardware processor, a plurality of manifold learning algorithms to process the joint manifold to obtain raw manifold learning results, wherein a dimension of the manifold learning results is less than a dimension of the joint manifold; processing the raw manifold learning results to obtain intrinsic parameters of the targeting objects; evaluating the multiple manifold learning algorithms based on the raw manifold learning results and the intrinsic parameters to determine one or more optimum manifold learning algorithms; and applying the one or more optimum manifold learning algorithms to fuse heterogeneous sensor data generated by the plurality sensors.
FILED Tuesday, January 23, 2018
APPL NO 15/878188
ART UNIT 2488 — Recording and Compression
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 13/58 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/0063 (20130101)
G06K 9/685 (20130101)
G06K 9/6248 (20130101)
G06K 9/6288 (20130101) Original (OR) Class
G06K 2009/6871 (20130101)

Computer Systems Based on Specific Computational Models
G06N 7/08 (20130101)

Image Data Processing or Generation, in General
G06T 7/80 (20170101)
G06T 2207/10048 (20130101)
G06T 2207/20081 (20130101)
G06T 2207/30252 (20130101)

Pictorial Communication, e.g Television
H04N 5/33 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11210806 Qian et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) ObjectVideo Labs, LLC (Tysons, Virginia)
ASSIGNEE(S) ObjectVideo Labs, LLC (Tysons, Virginia)
INVENTOR(S) Gang Qian (McLean, Virginia);  Yunxian Zhou (Herndon, Virginia);  David Conger (Sterling, Virginia);  Allison Beach (Leesburg, Virginia)
ABSTRACT Methods and apparatus are disclosed for enhancing urban surface model with image data obtained from a satellite image. Three dimensional models of an urban cityscape obtained from digital surface models may comprise surface location information but lack image information associated with the cityscape, such as the color and texture of building facades. The location of the satellite at the time of recording the satellite image interest may be obtained from metadata associated with the satellite image. A 3D model of a cityscape corresponding to the satellite image may be subjected to a transformation operation to determine portions of the 3D model that are viewable from a location corresponding to the location of the satellite when taking the picture. Visible facades buildings of the 3D model ma be identified and mapped to portions of the satellite image which may then be used in rendering 2D images from the 3D model. In some examples a satellite image projection model may be adjusted to more accurately determine geolocations of portions of the satellite image by analysis of a plurality of satellite images.
FILED Wednesday, August 21, 2019
APPL NO 16/546393
ART UNIT 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Image Data Processing or Generation, in General
G06T 7/60 (20130101) Original (OR) Class
G06T 15/04 (20130101)
G06T 2207/10032 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11210836 Amer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
U.S. Army
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) SRI International (Menlo Park, California)
ASSIGNEE(S) SRI International (Menlo Park, California)
INVENTOR(S) Mohamed R. Amer (Brooklyn, New York);  Xiao Lin (Princeton, New Jersey)
ABSTRACT This disclosure describes techniques that include generating, based on a description of a scene, a movie or animation that represents at least one possible version of a story corresponding to the description of the scene. This disclosure also describes techniques for training a machine learning model to generate predefined data structures from textual information, visual information, and/or other information about a story, an event, a scene, or a sequence of events or scenes within a story. This disclosure also describes techniques for using GANs to generate, from input, an animation of motion (e.g., an animation or a video clip). This disclosure also describes techniques for implementing an explainable artificial intelligence system that may provide end users with information (e.g., through a user interface) that enables an understanding of at least some of the decisions made by the AI system.
FILED Friday, December 21, 2018
APPL NO 16/231020
ART UNIT 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Electric Digital Data Processing
G06F 16/345 (20190101)
G06F 16/738 (20190101)
G06F 16/9024 (20190101)
G06F 40/205 (20200101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00335 (20130101)
G06K 9/00342 (20130101)
G06K 9/00718 (20130101)
G06K 9/00744 (20130101)
G06K 9/6215 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 3/084 (20130101)
G06N 3/088 (20130101)
G06N 3/0445 (20130101)
G06N 3/0454 (20130101)
G06N 20/00 (20190101)

Image Data Processing or Generation, in General
G06T 7/251 (20170101)
G06T 13/40 (20130101)
G06T 13/80 (20130101) Original (OR) Class
G06T 2207/10016 (20130101)
G06T 2207/20081 (20130101)
G06T 2207/20084 (20130101)
G06T 2207/30196 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11211205 Cao et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida);  GENERAL CAPACITOR, LLC (Tallahassee, Florida)
ASSIGNEE(S) THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida)
INVENTOR(S) Wanjun Cao (Tallahassee, Florida);  Jian-ping Zheng (Tallahassee, Florida)
ABSTRACT The present invention is directed to a method for pre-lithiation of negative electrodes during lithium loaded electrode manufacturing for use in lithium-ion capacitors. There is provided a system and method of manufacture of LIC electrodes using thin lithium film having holes therein, and in particular, to the process of manufacturing lithium loaded negative electrodes for lithium-ion capacitors by pre-lithiating electrodes with thin lithium metal films, wherein the thin lithium metal films include holes therein, and the lithium loaded negative electrodes are manufactured using a roll-to-roll lamination manufacturing, process.
FILED Monday, August 10, 2020
APPL NO 16/989622
ART UNIT 2812 — Semiconductors/Memory
CURRENT CPC
Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 11/06 (20130101)
H01G 11/14 (20130101)
H01G 11/50 (20130101) Original (OR) Class
H01G 11/54 (20130101)
H01G 11/86 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/13 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11211306 Ellis et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Research Laboratory (AFRL)
United States Air Force (USAF)
APPLICANT(S) ELEMENT SIX TECHNOLOGIES LIMITED (Didcot, United Kingdom)
ASSIGNEE(S) ELEMENT SIX TECHNOLOGIES LIMITED (Didcot, United Kingdom)
INVENTOR(S) Julian Ellis (Didcot, United Kingdom);  John Brandon (Didcot, United Kingdom);  Francis Mark Reininger (Pasadena, California)
ABSTRACT A synthetic diamond plate comprising a polygonal plate formed of synthetic diamond material, the polygonal plate of synthetic diamond material having a thickness in a range 0.4 mm to 1. mm, and rounded corners having a radius of curvature in a range 1 mm to 6 mm. A mounted synthetic diamond plate is also disclosed comprising a polygonal synthetic diamond plate as described and a base to which the polygonal synthetic diamond plate is bonded, wherein the base comprises a cooling channel. An array of mounted synthetic diamond plates is also described, comprising a plurality of mounted synthetic diamond plates described above, wherein the cooling channels of the mounted synthetic diamond plates are linked to form a common cooling channel across the array of mounted synthetic diamond plates.
FILED Friday, December 15, 2017
APPL NO 16/464397
ART UNIT 2814 — Semiconductors/Memory
CURRENT CPC
Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 25/18 (20130101)
C30B 29/04 (20130101)
C30B 29/64 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 23/3732 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11211418 Arbabi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) SAMSUNG ELECTRONICS CO., LTD. (Suwon-si, South Korea);  CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) SAMSUNG ELECTRONICS CO., LTD. (Suwon-si, South Korea);  CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Amir Arbabi (Pasadena, California);  Seunghoon Han (Suwon-si, South Korea);  Andrei Faraon (Pasadena, California);  Hyeonsoo Park (Suwon-si, South Korea)
ABSTRACT An image sensor includes a substrate, thin lenses disposed on a first surface of the substrate and configured to concentrate lights incident on the first surface, and light-sensing cells disposed on a second surface of the substrate, the second surface facing the first surface, and the light-sensing cells being configured to sense lights passing through the thin lenses, and generate electrical signals based on the sensed lights. A first thin lens and second thin lens of the thin lenses are configured to concentrate a first light and a second light, respectively, of the incident lights onto the light-sensing cells, the first light having a different wavelength than the second light.
FILED Friday, August 21, 2020
APPL NO 16/999627
ART UNIT 2878 — Optics
CURRENT CPC
Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor
G03B 35/10 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/14605 (20130101)
H01L 27/14621 (20130101)
H01L 27/14627 (20130101) Original (OR) Class

Pictorial Communication, e.g Television
H04N 5/2257 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11211509 Cornfeld et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
United States Air Force (USAF)
APPLICANT(S) SolAero Technologies Corp. (Albuquerque, New Mexico)
ASSIGNEE(S) SolAero Technologies Corp. (Albuquerque, New Mexico)
INVENTOR(S) Arthur Cornfeld (Sandy Springs, Georgia);  Mark A. Stan (Albuquerque, New Mexico)
ABSTRACT A multijunction solar cell includes an InGaAs buffer layer and an InGaAlAs grading interlayer disposed below, and adjacent to, the InGaAs buffer layer. The grading interlayer achieves a transition in lattice constant from one solar subcell to another solar subcell.
FILED Tuesday, November 19, 2019
APPL NO 16/688745
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/06 (20130101) Original (OR) Class
H01L 31/184 (20130101)
H01L 31/0693 (20130101)
H01L 31/1844 (20130101)
H01L 31/03046 (20130101)
H01L 31/06875 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/544 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11211546 Szelag et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Secretary of the Navy (SECNAV)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island);  Pamela Benjamin (Somerset, Massachusetts)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (, None)
INVENTOR(S) Jeffrey A Szelag (Tiverton, Rhode Island);  Michael R Zarnetske (Bristol, Rhode Island);  Kim C Benjamin (Somerset, Massachusetts)
ABSTRACT A method for applying a waterproof coating to a transducer component includes the steps of cleaning and promoting bonding on the transducer component by immersing the component in a mixture of isopropyl alcohol, deionized water, and siline. The component is then air dried and rinsed in pure isopropyl alcohol. After drying, the component is vacuum baked and subjected to a vacuum for twelve hours. A parylene coating is provided to the component surface. The parylene coating is abraded, and the surface is rinsed with pure isopropyl alcohol. After drying, polyurethane is provided on the abraded parylene surface. The polyurethane is cured to form a waterproof coating on the transducer component. In further embodiments, a second parylene coating can be provided outside the polyurethane.
FILED Wednesday, June 10, 2020
APPL NO 16/897536
ART UNIT 1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Processes for Applying Fluent Materials to Surfaces, in General
B05D 3/108 (20130101)
B05D 3/0218 (20130101)
B05D 3/0406 (20130101)
B05D 5/00 (20130101)
B05D 7/24 (20130101)
B05D 7/544 (20130101)

Cleaning in General; Prevention of Fouling in General
B08B 3/08 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 147/00 (20130101)
C09D 175/04 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 41/23 (20130101) Original (OR) Class
H01L 41/183 (20130101)
H01L 41/0533 (20130101)
H01L 41/0825 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11211675 Tomasic et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Secretary of the Air Force (SECAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S)
INVENTOR(S) Boris Tomasic (Harvard, Massachusetts);  Carl R. Pfeiffer (Beavercreek, Ohio);  Thomas P. Steffen (Xenia, Ohio)
ABSTRACT A linear-to-circular polarizer antenna is disclosed. In accordance with embodiments of the invention, the polarizer antenna includes an antenna operable to transmit and receive polarized signals and a linear-to-circular polarizer coupled to the antenna. The polarizer includes a plurality of cascaded elements, waveplates or anisotropic sheets, having biaxial permittivity. Each cascaded element has a principal axis rotated at different angles relative to an adjacent element about a z-axis of a 3-dimensional x, y, z coordinate system, and each element is composed of an artificial anisotropic dielectric. The polarizer further includes impedance matching layers disposed adjacent the cascaded elements.
FILED Tuesday, November 27, 2018
APPL NO 16/201037
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 27/286 (20130101)

Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 1/17 (20130101) Original (OR) Class
H01P 1/171 (20130101)
H01P 1/172 (20130101)
H01P 1/173 (20130101)
H01P 11/00 (20130101)

Antennas, i.e Radio Aerials
H01Q 3/40 (20130101)
H01Q 3/2676 (20130101)
H01Q 5/335 (20150115)
H01Q 15/04 (20130101)
H01Q 15/24 (20130101)
H01Q 15/244 (20130101)
H01Q 15/246 (20130101)
H01Q 21/0031 (20130101)
H01Q 21/064 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11211820 Gong et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Songbin Gong (Champaign, Illinois);  Yansong Yang (Urbana, Illinois);  Justin Postma (Twin Falls, Idaho);  Liuqing Gao (Champaign, Illinois);  Brandon Arakawa (Tempe, Arizona)
ABSTRACT An inductive wireless power transfer apparatus includes a source coil coupled to a power source such that current flows through the source coil when the source coil is excited by the power source. The apparatus further includes a first capacitor coupled in series to the source coil. The apparatus further includes an intermediate coil surrounding the source coil and positioned within an identical plane as the source coil, and a second capacitor coupled in series to the intermediate coil. The capacitances of the first capacitor and the second capacitor are set to tune out self-inductances of the source coil and the intermediate coil. In embodiments, the source coil is to inductively power the intermediate coil, which is to inductively power a load coil positioned a distance away from the intermediate coil.
FILED Monday, May 14, 2018
APPL NO 15/979065
ART UNIT 2836 — Electrical Circuits and Systems
CURRENT CPC
Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 50/05 (20160201)
H02J 50/12 (20160201) Original (OR) Class
H02J 50/50 (20160201)
H02J 50/80 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 11207422 Coleman et al.
FUNDED BY
Department of Energy (DOE)
Lawrence Livermore National Laboratory (LLNL)
Lawrence Livermore National Security LLC (LLNS)
APPLICANT(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
ASSIGNEE(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
INVENTOR(S) Matthew A. Coleman (Oakland, California);  Nicholas O. Fischer (Livermore, California);  Amy Rasley (Livermore, California);  Craig D. Blanchette (San Leandro, California);  Todd Peterson (Coronado, California)
ABSTRACT A telodendrimer-nanolipoprotein particle (t-NLP), comprising one or more membrane forming lipids, one or more telodendrimers, and a scaffold protein and a Chlamydia major outer membrane protein (MOMP) comprising a MOMP hydrophobic region, and related compositions methods and systems.
FILED Tuesday, May 01, 2018
APPL NO 16/609420
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/0043 (20130101)
A61K 9/1273 (20130101)
A61K 9/1277 (20130101)
A61K 39/39 (20130101)
A61K 39/0208 (20130101)
A61K 47/6915 (20170801) Original (OR) Class
A61K 2039/54 (20130101)
A61K 2039/543 (20130101)
A61K 2039/545 (20130101)
A61K 2039/6018 (20130101)
A61K 2039/6093 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207614 Werner
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FE)
APPLICANT(S) University of Kentucky Research Foundation (Lexington, Kentucky)
ASSIGNEE(S) University of Kentucky Research Foundation (Lexington, Kentucky)
INVENTOR(S) Joshua Michael Werner (Lexington, Kentucky)
ABSTRACT A single stage clarifier mixing assembly includes a housing having a circular sidewall and a center axis, a mixing section in the housing, a clarifier section overlying and axially aligned with the mixing section along the center axis within the housing, an inlet delivering an inlet stream to the mixing section and an agitator. The agitator is adapted for mixing the inlet stream in the mixing chamber.
FILED Thursday, July 23, 2020
APPL NO 16/937032
ART UNIT 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 21/0042 (20130101)
B01D 21/0048 (20130101)
B01D 21/0057 (20130101)
B01D 21/286 (20130101)
B01D 21/2405 (20130101) Original (OR) Class
B01D 21/2427 (20130101)

Mixing, e.g Dissolving, Emulsifying, Dispersing
B01F 7/00341 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207634 Irvin et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FE)
APPLICANT(S) University of Kentucky Research Foundation (Lexington, Kentucky)
ASSIGNEE(S) University of Kentucky Research Foundation (Lexington, Kentucky)
INVENTOR(S) Bradley David Irvin (Lexington, Kentucky);  Amanda Warriner (Lexington, Kentucky);  Leland R. Widger (St. Clair, Michigan);  Kunlei Liu (Lexington, Kentucky)
ABSTRACT A method and apparatus are provided for recovering an amine solvent from an acid gas stream. The apparatus includes a water wash recovery column, a nozzle for spraying water wash and an amine nucleation agent into the water wash recovery column and an inlet port for introducing acid gas into the water wash recovery column adjacent the lower end thereof. The method includes the steps of treating the acid gas stream in the water wash recovery column with a counter-current flow of water wash in an amine nucleation agent, discharging treated acid gas from an upper end of the water wash recovery column and collecting water wash, amine nucleation agent and entrained amine solvent from the acid gas stream and a sump at a lower end of the water wash recovery column.
FILED Tuesday, July 02, 2019
APPL NO 16/460229
ART UNIT 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 47/06 (20130101)
B01D 47/14 (20130101)
B01D 53/002 (20130101)
B01D 53/78 (20130101)
B01D 53/96 (20130101)
B01D 53/1425 (20130101)
B01D 53/1475 (20130101) Original (OR) Class
B01D 53/1493 (20130101)
B01D 2252/204 (20130101)
B01D 2257/504 (20130101)
B01D 2258/0283 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207658 Matteo et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
National Technology and Engineering Solutions of Sandia, LLC (NTESS)
Sandia National Laboratories (SNL)
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Edward N. Matteo (Albuquerque, New Mexico);  Clay Payne (Albuquerque, New Mexico);  Amanda Sanchez (Albuquerque, New Mexico);  Nelson S. Bell (Albuquerque, New Mexico);  Yifeng Wang (Albuquerque, New Mexico);  Jessica N. Kruichak (Albuquerque, New Mexico);  Melissa Marie Mills (Albuquerque, New Mexico)
ABSTRACT An anionic sorption agent, method for forming the anionic sorption agent and a barrier system are disclosed. The anionic sorption agent including a modified pseudo or glycol-boehmite base comprising a structure having cationic metal ion sites. The method for forming the anionic sorption agent includes providing a pseudo or glycol-boehmite base and contacting the pseudo or glycol-boehmite base a modifying composition comprising a metallic ion to form the modified pseudo or glycol-boehmite base comprising a structure having cationic metal ion sites. The barrier system includes the anionic sorption agent comprising a first barrier component comprising a modified pseudo or glycol-boehmite base comprising a structure having cationic metal ion sites and a second barrier component comprising a cationic sorption agent.
FILED Friday, December 08, 2017
APPL NO 15/836331
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/08 (20130101)
B01J 20/223 (20130101) Original (OR) Class
B01J 20/28061 (20130101)
B01J 20/28064 (20130101)
B01J 20/28066 (20130101)
B01J 41/09 (20170101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207662 Berry et al.
FUNDED BY
Department of Energy (DOE)
National Energy Technology Laboratory (NETL)
APPLICANT(S) United States Department of Energy (Washington, District of Columbia)
ASSIGNEE(S) U.S. Department of Energy (Washington, District of Columbia)
INVENTOR(S) David A. Berry (Mount Morris, Pennsylvania);  Dushyant Shekhawat (Morgantown, West Virginia);  Daniel J. Haynes (Morgantown, West Virginia);  Mark W. Smith (Fairmont, West Virginia)
ABSTRACT One or more embodiments relates to a method of catalytically converting a reactant gas mixture for pollution abatement of products of hydrocarbon fuel combustion. The method provides substituted mixed-metal oxides where catalytically active metals are substituted within the crystal lattice to create an active and well dispersed metal catalyst available to convert the reactant gas mixture. Embodiments may be used with gasoline and diesel fueled internal combustion engine exhaust, although specific embodiments may differ somewhat for each.
FILED Wednesday, May 20, 2020
APPL NO 16/879203
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 53/945 (20130101)
B01D 2255/40 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 23/002 (20130101) Original (OR) Class
B01J 35/04 (20130101)
B01J 35/0006 (20130101)
B01J 35/026 (20130101)

Gas-flow Silencers or Exhaust Apparatus for Machines or Engines in General; Gas-flow Silencers or Exhaust Apparatus for Internal Combustion Engines
F01N 3/035 (20130101)
F01N 3/101 (20130101)
F01N 3/0814 (20130101)
F01N 2570/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207672 Lee et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Laboratory (LANL)
Los Alamos National Security, LLC (LANS)
National Science Foundation (NSF)
APPLICANT(S) RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York)
ASSIGNEE(S) Rensselaer Polytechnic Institute (Troy, New York)
INVENTOR(S) Sangwoo Lee (Cohoes, New York);  Chulsung Bae (Cohoes, New York);  Musashi J. Briem (Troy, New York);  Sungmin Park (Troy, New York)
ABSTRACT The anion exchange membranes exhibit enhanced chemical stability and ion conductivity when compared with traditional styrene-based alkaline anion exchange membranes. A copolymer backbone is polymerized from a reaction medium that includes a diphenylalkylene and an alkadiene. The copolymer includes a plurality of pendant phenyl groups. The diphenyl groups on the polymer backbone are functionalized with one or more haloalkylated precursor substrates. The terminal halide from the precursor substrate can then be substituted with a desired ionic group. The diphenylethylene-based alkaline anion exchange membranes lack the α-hydrogens sharing tertiary carbons with phenyl groups from polystyrene or styrene-based precursor polymers, resulting in higher chemical stability. The ionic groups are also apart from each other by about 3 to 6 carbons in the polymer backbone, enhancing ion conductivity. These membrane are advantageous for use in fuel cells, electrolyzers employing hydrogen, ion separations, etc.
FILED Tuesday, October 22, 2019
APPL NO 17/287639
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Separation
B01D 61/44 (20130101)
B01D 71/06 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 41/07 (20170101) Original (OR) Class
B01J 41/14 (20130101)
B01J 47/12 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/469 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 212/32 (20130101)
C08F 2810/00 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 5/2287 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208322 Walczak et al.
FUNDED BY
Department of Energy (DOE)
Joint Center for Artificial Photosynthesis (JCAP)
Lawrence Berkeley National Laboratory (LBNL)
Office of Science (DOE-SC)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Karl A. Walczak (Albuquerque, New Mexico);  Jeffrey W. Beeman (El Sobrante, California);  Ian D. Sharp (Garching, Germany)
ABSTRACT This disclosure provides systems, methods, and apparatus related to a solar fuel generator. In one aspect, a device includes a photovoltaic cell, the photovoltaic cell having a first surface and a second surface, a mesh disposed on the first surface of the photovoltaic cell, and a polymer disposed on the mesh and on the first surface of the photovoltaic cell. The mesh has a catalyst disposed thereon. The polymer covers the first surface of the photovoltaic cell, with at least a portion of the mesh not being covered with the polymer.
FILED Friday, January 11, 2019
APPL NO 16/245595
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 3/04 (20130101)
C01B 3/042 (20130101) Original (OR) Class
C01B 3/047 (20130101)

Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 1/00 (20130101)
C25B 1/04 (20130101)
C25B 1/55 (20210101)
C25B 3/25 (20210101)
C25B 9/05 (20210101)
C25B 9/19 (20210101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/36 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208334 Balema et al.
FUNDED BY
Department of Energy (DOE)
Ames Laboratory (AL)
Office of Science (DOE-SC)
APPLICANT(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
ASSIGNEE(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
INVENTOR(S) Viktor Balema (Ames, Iowa);  Ihor Hlova (Ames, Iowa);  Vitalij K. Pecharsky (Ames, Iowa)
ABSTRACT A method embodiment involves preparing single metal or mixed transition metal chalcogenide using exfoliation of two or more different bulk transition metal dichalcogenides in a manner to form an intermediate hetero-layered transition metal chalcogenide structure, which can be treated to provide a single-phase transition metal chalcogenide.
FILED Thursday, July 26, 2018
APPL NO 15/998266
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Crushing, Pulverising, or Disintegrating in General; Milling Grain
B02C 15/004 (20130101)
B02C 19/06 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 19/002 (20130101)

Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 39/06 (20130101) Original (OR) Class
C01G 41/00 (20130101)
C01G 41/006 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/01 (20130101)
C01P 2002/72 (20130101)
C01P 2002/85 (20130101)
C01P 2002/88 (20130101)
C01P 2004/03 (20130101)
C01P 2004/04 (20130101)
C01P 2004/20 (20130101)
C01P 2004/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208366 Weaver et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Jason F. Weaver (Gainesville, Florida);  Yingxue Bian (Golden, Colorado)
ABSTRACT Methods of converting ethane to ethylene at relatively low temperatures are described. Ir02-based catalysts are used in the conversion. Methods of converting a base gas to a first gas by exposing the base gas to an IrO2-based catalyst and forming the first gas are described. The base gas can be an alkane. The first gas can include an alkene, an alkyne, an alcohol, an aldehyde, or combinations thereof.
FILED Friday, January 18, 2019
APPL NO 16/959325
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 23/468 (20130101)

Acyclic or Carbocyclic Compounds
C07C 5/3337 (20130101) Original (OR) Class
C07C 11/04 (20130101)
C07C 2523/46 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208534 Guan
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Zhibin Guan (Irvine, California)
ABSTRACT The disclosure provides for dynamic polymers based on silyl ether exchange that are malleable and recyclable which have favorable mechanical properties and chemical resistance, methods of making thereof, and uses and applications thereof.
FILED Tuesday, June 26, 2018
APPL NO 16/019500
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 8/44 (20130101)
C08F 8/44 (20130101)
C08F 12/22 (20130101)
C08F 12/24 (20130101)
C08F 12/24 (20130101)
C08F 212/08 (20130101)
C08F 212/08 (20130101)
C08F 212/14 (20130101)
C08F 212/24 (20200201)
C08F 216/06 (20130101)
C08F 220/20 (20130101)
C08F 230/08 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 3/24 (20130101) Original (OR) Class
C08J 2325/18 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 5/5415 (20130101)

Compositions of Macromolecular Compounds
C08L 2312/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208571 Wang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) University of Maryland, College Park (College Park, Maryland)
ASSIGNEE(S) UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland)
INVENTOR(S) YuHuang Wang (Laurel, Maryland);  Peng Wang (Rockville, Maryland);  Mijin Kim (New York, New York);  Chiyu Zhang (Berwyn Heights, Maryland)
ABSTRACT A method termed “superacid-surfactant exchange” (S2E) for the dispersion of carbon nanomaterials in aqueous solutions. This S2E method enables nondestructive dispersion of carbon nanomaterials (including single-walled carbon nanotubes, double-walled carbon nanotubes, multi-wall carbon nanotubes, and graphene) at rapidly and at large scale in aqueous solution without a requirement for expensive or complicated equipment. Dispersed carbon nanotubes obtained from this method feature long length, low defect density, high electrical conductivity, and in the case of semiconducting single-walled carbon nanotubes, bright photoluminescence in the near-infrared.
FILED Thursday, August 08, 2019
APPL NO 16/536166
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 32/19 (20170801)
C01B 32/21 (20170801)
C01B 32/156 (20170801)
C01B 32/159 (20170801)
C01B 32/172 (20170801)
C01B 32/174 (20170801)
C01B 32/194 (20170801)
C01B 2202/02 (20130101)
C01B 2202/04 (20130101)
C01B 2202/06 (20130101)
C01B 2202/22 (20130101)
C01B 2202/28 (20130101)
C01B 2202/34 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 11/037 (20130101)
C09D 11/52 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208628 Strano et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
APPLICANT(S) Michael S. Strano (Lexington, Massachusetts);  Juan Pablo Giraldo Gomez (Somerville, Massachusetts);  Sean Mitchell Faltermeier (Cambridge, Massachusetts);  Markita P. Landry (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) Michael S. Strano (Lexington, Massachusetts);  Juan Pablo Giraldo Gomez (Somerville, Massachusetts);  Sean Mitchell Faltermeier (Cambridge, Massachusetts);  Markita P. Landry (Cambridge, Massachusetts)
ABSTRACT In one aspect, a composition can include an organelle, and a nanoparticle having a zeta potential of less than −10 mV or greater than 10 mV contained within the organelle. In a preferred embodiment, the organelle can be a chloroplast and the nanoparticle can be a single-walled carbon nanotube associated with a strongly anionic or strongly cationic polymer.
FILED Thursday, August 07, 2014
APPL NO 14/454196
ART UNIT 1663 — Plants
CURRENT CPC
New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques
A01H 3/00 (20130101)
A01H 5/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/04 (20130101) Original (OR) Class
C12N 15/87 (20130101)
C12N 15/8207 (20130101)
C12N 15/8212 (20130101)
C12N 15/8214 (20130101)
C12N 15/8269 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208641 Spodsberg
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Novozymes, Inc. (Davis, California)
ASSIGNEE(S) Novozymes, Inc. (Davis, California)
INVENTOR(S) Nikolaj Spodsberg (Bagsvaerd, Denmark)
ABSTRACT The present invention relates to isolated polypeptides having cellobiohydrolase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
FILED Wednesday, April 03, 2019
APPL NO 16/374131
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/2437 (20130101) Original (OR) Class

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/14 (20130101)
C12P 19/02 (20130101)
C12P 19/14 (20130101)
C12P 2203/00 (20130101)

Enzymes
C12Y 302/01091 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 50/10 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 20/52 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208642 Beckham et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
Alliance for Sustainable Energy, LLC (ASE)
National Renewable Energy Laboratory (NREL)
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  Montana State University (Bozeman, Montana);  University of Portsmouth (Portsmouth, United Kingdom)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  Montana State University (Bozeman, Montana);  University of Portsmouth (Portsmouth, United Kingdom)
INVENTOR(S) Gregg Tyler Beckham (Golden, Colorado);  Jennifer DuBois (Bozeman, Montana);  Melodie M. Machovina (Urbana, Illinois);  Simon James Bradshaw Mallinson (Oxford, United Kingdom);  John E. McGeehan (Portsmouth, United Kingdom);  Christopher W. Johnson (Denver, Colorado);  Alexander William Meyers (Denver, Colorado)
ABSTRACT Disclosed herein are compositions of non-naturally occurring enzymes to enable microbial syringol utilization with GcoAB.
FILED Thursday, November 14, 2019
APPL NO 16/684206
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/2437 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208666 Brandon et al.
FUNDED BY
Department of Energy (DOE)
Lawrence Berkeley National Laboratory (LBNL)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Andrew Brandon (Berkeley, California);  Henrik Vibe Scheller (Millbrae, California);  Dominique Loque (Vernier, Switzerland)
ABSTRACT The present invention provides for a polypeptide capable of dominant suppression of a first naturally occurring IRX10, wherein the polypeptide comprises an amino acid sequence having at least 70% identity as compared to a second naturally occurring IRX10 wherein the polypeptide comprises one or more of the conserved amino acid indicated in FIG. 2 substituted with a different amino acid residue.
FILED Tuesday, December 19, 2017
APPL NO 15/847788
ART UNIT 1663 — Plants
CURRENT CPC
Peptides
C07K 14/415 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1077 (20130101)
C12N 15/8202 (20130101)
C12N 15/8216 (20130101) Original (OR) Class
C12N 15/8246 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209219 Youchison
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
National Technology and Engineering Solutions of Sandia, LLC (NTESS)
Sandia National Laboratories (SNL)
APPLICANT(S) Sandia Corporation (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Dennis L. Youchison (Albuquerque, New Mexico)
ABSTRACT A heat exchanger is disclosed that includes a cold heat exchange zone including a foam material having an annular geometry and having fluid distribution and collection slots configured to distribute a cooling fluid circumferentially through the foam material.
FILED Wednesday, September 11, 2013
APPL NO 14/024101
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Details of Heat-exchange and Heat-transfer Apparatus, of General Application
F28F 1/10 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209249 Rhodes et al.
FUNDED BY
Department of Energy (DOE)
Lawrence Livermore National Laboratory (LLNL)
Lawrence Livermore National Security LLC (LLNS)
APPLICANT(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Mark Rhodes (Pleasanton, California);  Chadd M. May (Livermore, California)
ABSTRACT Exploding foil initiator apparatus, system, and method that improve the current density in the bridge region by modifying the shape and dimensions of the bridge and related components. The exploding foil initiator reduces burn-back by making areas of the bridge thicker except directly under the flyer. The exploding foil initiator boards are built so the flyer is not connected to the rest of the top cover-lay. This avoids losing energy due to the flyer having to tear away from the solid cover-lay.
FILED Friday, August 17, 2018
APPL NO 16/639974
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 3/11 (20130101)
F42B 3/121 (20130101)
F42B 3/124 (20130101) Original (OR) Class
F42B 3/127 (20130101)
F42B 3/128 (20130101)

Ammunition Fuzes; Arming or Safety Means Therefor
F42C 19/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209390 Ha et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Noel Seunghyun Ha (Los Angeles, California);  R. Michael Van Dam (Los Angeles, California);  Jimmy Ly (San Francisco, California)
ABSTRACT A volumetric microfluidic injector for capillary electrophoresis (CE) for highly repeatable sample injection has been designed and built to eliminate known injection bias in hydrodynamic injection. A defined volume from 1-10 nL or 0.1-100 nL of sample is confined in a defined region of a micro-valve PDMS microfluidic injector chip and electrophoretic potential is applied to drive sample into a separation device such as an embedded fused silica capillary for separation and detection. Using a 75 μm ID capillary, the RSD of an absorbance peak area as low as 1.32% (n=11) is obtained. As a comparison, the time-dependent injection was tested using the same chip which resulted in an inferior repeatability.
FILED Friday, October 06, 2017
APPL NO 16/339348
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/50273 (20130101)
B01L 3/502738 (20130101)
B01L 2400/0421 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/453 (20130101)
G01N 27/44743 (20130101)
G01N 27/44791 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209393 Garimella et al.
FUNDED BY
Department of Energy (DOE)
Battelle Memorial Institute (BATTELLE)
Pacific Northwest National Laboratory (PNNL)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Venkata B S Garimella (Richland, Washington);  Ahmed M. Hamid (Richland, Washington);  Yehia M. Ibrahim (West Richland, Washington);  Richard D. Smith (Richland, Washington)
ABSTRACT Methods and apparatuses for ion manipulations, including ion trapping, transfer, and mobility separations, using traveling waves (TW) formed by continuous alternating current (AC) are disclosed. An apparatus for ion manipulation includes a surface to which are coupled a first plurality of continuous electrodes and a second plurality of segmented electrodes. The second plurality of segmented electrodes is arranged in longitudinal sets between or adjacent to the first plurality of electrodes. An RF voltage applied to adjacent electrodes of the first plurality of electrodes is phase shifted by approximately 180° to confine ions within the apparatus. An AC voltage waveform applied to adjacent electrodes within a longitudinal set of the second plurality of segmented electrodes is phase shifted on the adjacent electrodes by 1°-359° to move ions longitudinally through the apparatus for separation.
FILED Monday, May 06, 2019
APPL NO 16/404472
ART UNIT 2881 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/624 (20130101) Original (OR) Class

Electric Discharge Tubes or Discharge Lamps
H01J 49/26 (20130101)
H01J 49/0027 (20130101)
H01J 49/062 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209423 Beer et al.
FUNDED BY
Department of Energy (DOE)
Lawrence Livermore National Laboratory (LLNL)
Lawrence Livermore National Security LLC (LLNS)
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) N. Reginald Beer (Pleasanton, California);  Steven W. Bond (Livermore, California)
ABSTRACT The disclosed technology includes a planar device for performing multiple biochemical assays at the same time, or nearly the same time. Each assay may include a biosample including a biochemical, enzyme, DNA, and/or any other biochemical or biological sample. Each assay may include one or more tags including dyes and/or other chemicals/reagents whose optical characteristics change based on chemical characteristics of the biological sample being tested. Each assay may be optically pumped to cause one or more of luminescence, phosphorescence, or fluorescence of the assay that may be detected by one or more optical detectors. For example, an assay may include two tags and a biosample. Each tag may be pumped by different wavelengths of light and may produce different wavelengths of light that is filtered and detected by one or more detectors. The pump wavelengths may be different from one another and different from the produced wavelengths.
FILED Tuesday, July 24, 2018
APPL NO 16/043808
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/50 (20130101)
B01L 2300/0609 (20130101)
B01L 2300/0887 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101)
C12Q 1/6806 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/64 (20130101)
G01N 33/521 (20130101)
G01N 33/525 (20130101) Original (OR) Class
G01N 33/54366 (20130101)
G01N 2021/6419 (20130101)
G01N 2021/6421 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209469 Liu et al.
FUNDED BY
Department of Energy (DOE)
UT-Battelle, LLC (UT-BATTELLE)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) University of Tennessee Research Foundation (Knoxville, Tennessee)
ASSIGNEE(S) UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee);  UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Yilu Liu (Knoxville, Tennessee);  Wenpeng Yu (Knoxville, Tennessee);  Wenxuan Yao (Knoxville, Tennessee)
ABSTRACT A method includes performing by a processor: receiving a plurality of synchrophasor measurements of a power system signal associated with a time interval from a phasor measurement unit (PMU), each of the plurality of synchrophasor measurements including a phase angle, frequency value, and a timestamp associated with the synchrophasor measurement, determining a plurality of relative phase angles based on the plurality of phase angles, determining a correlation coefficient between the plurality of relative phase angles and a plurality of corresponding frequency values of the power system signal, and detecting an error in the plurality of timestamps based on the correlation coefficient; estimating the error in the plurality of timestamps based on the plurality of relative phase angles and the plurality of corresponding frequency values.
FILED Tuesday, May 21, 2019
APPL NO 16/418540
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 19/2513 (20130101)
G01R 25/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209714 Gowda et al.
FUNDED BY
Department of Energy (DOE)
Lawrence Livermore National Laboratory (LLNL)
Lawrence Livermore National Security LLC (LLNS)
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Apurva Shantharaj Gowda (Mountain View, California);  Jacky Chak-Kee Chan (Livermore, California);  Peter Thomas Setsuda DeVore (Livermore, California);  David Simon Perlmutter (Oakland, California);  Jason Thomas Chou (Walnut Creek, California)
ABSTRACT Devices, methods and systems for generating wideband, high-fidelity arbitrary radio frequency (RF) passband signals are described. A voltage tunable optical filter for arbitrary RF passband signal generation includes a first input configured to receive a broadband optical pulse train, a second input configured to receive a first control voltage representative of an amplitude signal, an electrooptic modulator to receive the broadband optical pulse train and the first control voltage, to modulate the broadband optical pulse train in accordance with the amplitude signal, and to produce two complementary optical outputs that form two arms of an interferometer, an optical delay component to impart an optical path difference into one of the complementary outputs of the electrooptic modulator, and a combiner or a splitter to receive two complementary optical outputs of the electrooptic modulator after impartation of the optical path difference and to produce an output interference pattern of fringes.
FILED Friday, January 24, 2020
APPL NO 16/751839
ART UNIT 2636 — Optical Communications
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 5/20 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/21 (20130101) Original (OR) Class
G02F 1/0123 (20130101)
G02F 1/212 (20210101)

Multiplex Communication
H04J 14/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209716 Valentine et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) Vanderbuilt University (Nashville, Tennessee)
INVENTOR(S) Jason G. Valentine (Nashville, Tennessee);  Richard F. Haglund (Nashville, Tennessee);  Zhihua Zhu (Nashville, Tennessee);  Austin Howes (Nashville, Tennessee)
ABSTRACT According to some aspects, a transmissive and all-dielectric optical component/limiter with great cutoff efficiency using Vanadium Dioxide (VO2) as the active component is disclosed. In some embodiments, Vanadium dioxide is used for an optical limiter due to the large contrast in optical constants upon undergoing the semiconductor to metal phase transition. When triggered optically, this transition occurs within 60 fs, making the device suitable for an ultrafast laser environment. In addition, the phase transition threshold is tunable by applying stress or doping; therefore, the device cutoff intensity can be adjusted to fulfill specific requirements.
FILED Friday, October 04, 2019
APPL NO 16/593551
ART UNIT 2874 — Optics
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/3501 (20130101)
G02F 1/3507 (20210101)
G02F 1/3509 (20210101)
G02F 1/3523 (20130101) Original (OR) Class
G02F 1/3556 (20130101)
G02F 1/3558 (20130101)
G02F 2202/30 (20130101)
G02F 2203/15 (20130101)
G02F 2203/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11210089 Byrne et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Hewlett Packard Enterprise Development LP (Houston, Texas)
ASSIGNEE(S) Hewlett Packard Enterprise Development LP (Houston, Texas)
INVENTOR(S) John L. Byrne (Palo Alto, California);  Harumi Kuno (Palo Alto, California);  Jeffrey Drummond (Palo Alto, California)
ABSTRACT Methods and systems for conducting vector send operations are provided. The processor of a sender node receives a request to perform a collective send operation (e.g., MPI_Broadcast) from a user application, requesting a copy of data in one or more send buffers by sent to each of a plurality of destinations in a destination vector. The processor invokes a vector send operation from a software communications library, placing a remote enqueue atomic send command for each destination node of the destination vector in an entry of a transmit data mover (XDM) command queue in a single call. The processor executes all of the commands in the XDM command queue and writes the data in the one or more send buffers into each receive queue of each destination identified in the destination vector.
FILED Thursday, July 11, 2019
APPL NO 16/508769
ART UNIT 2184 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 9/544 (20130101)
G06F 9/546 (20130101)
G06F 9/30036 (20130101) Original (OR) Class
G06F 13/28 (20130101)
G06F 13/4027 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11210747 Frolik et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) University of Vermont and State Agricultural College (Burlington, Vermont)
ASSIGNEE(S) University of Vermont and State Agricultural College (Burlington, Vermont)
INVENTOR(S) Jeff Frolik (Burlington, Vermont);  Paul Hines (Burlington, Vermont);  Mads Almassalkhi (Burlington, Vermont)
ABSTRACT The present disclosure provides a distributed and anonymous approach to demand response of an electricity system. The approach conceptualizes energy consumption and production of distributed-energy resources (DERs) via discrete energy packets that are coordinated by a cyber computing entity that grants or denies energy packet requests from the DERs. The approach leverages a condition of a DER, which is particularly useful for (1) thermostatically-controlled loads, (2) non-thermostatic conditionally-controlled loads, and (3) bi-directional distributed energy storage systems. In a first aspect of the present approach, each DER independently requests the authority to switch on for a fixed amount of time (i.e., packet duration). The coordinator determines whether to grant or deny each request based electric grid and/or energy or power market conditions. In a second aspect, bi-directional DERs, such as distributed-energy storage systems (DESSs) are further able to request to supply energy to the grid.
FILED Thursday, September 21, 2017
APPL NO 15/712089
ART UNIT 2119 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electric Digital Data Processing
G06F 17/18 (20130101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 50/06 (20130101) Original (OR) Class

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 3/00 (20130101)
H02J 3/003 (20200101)
H02J 3/14 (20130101)
H02J 13/00 (20130101)

Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications
Y02B 70/3225 (20130101)

Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids
Y04S 20/222 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11211559 Forrest et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Stephen R. Forrest (Ann Arbor, Michigan);  Brian E. Lassiter (Ypsilanti, Michigan);  Jun Y. Lee (Seongnam-si, South Korea);  Kyoung S. Yook (Yongin-si, South Korea);  Soon O. Jeon (Seoul, South Korea);  Byung D. Chin (Seongnam-si, South Korea)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan);  Industry-Academic Cooperation Foundation Dankook University (Guepmgoo, South Korea)
INVENTOR(S) Stephen R. Forrest (Ann Arbor, Michigan);  Brian E. Lassiter (Ypsilanti, Michigan);  Jun Y. Lee (Seongnam-si, South Korea);  Kyoung S. Yook (Yongin-si, South Korea);  Soon O. Jeon (Seoul, South Korea);  Byung D. Chin (Seongnam-si, South Korea)
ABSTRACT There is disclosed ultrathin film material templating layers that force the morphology of subsequently grown electrically active thin films have been found to increase the performance of small molecule organic photovoltaic (OPV) cells. There is disclosed electron-transporting material, such as hexaazatriphenylene-hexacarbonitrile (HAT-CN) can be used as a templating material that forces donor materials, such as copper phthalocyanine (CuPc) to assume a vertical-standing morphology when deposited onto its surface on an electrode, such as an indium tin oxide (ITO) electrode. It has been shown that for a device with HAT-CN as the templating buffer layer, the fill factor and short circuit current of CuPc:C60 OPVs were both improved compared with cells lacking the HAT-CN template. This is explained by the reduction of the series resistance due to the improved crystallinity of CuPc grown onto the ITO surface.
FILED Friday, October 14, 2011
APPL NO 13/273753
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 10/00 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 51/001 (20130101)
H01L 51/0012 (20130101) Original (OR) Class
H01L 51/0046 (20130101)
H01L 51/0072 (20130101)
H01L 51/424 (20130101)
H01L 51/4246 (20130101)
H01L 51/4253 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/549 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 70/50 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11211773 Jung et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) TRANSWAVE PHOTONICS, LLC. (Austin, Texas)
ASSIGNEE(S) TRANSWAVE PHOTONICS, LLC. (Austin, Texas)
INVENTOR(S) Seungyong Jung (Austin, Texas);  Mikhail A. Belkin (Austin, Texas)
ABSTRACT A photonic integrated circuit device includes a passive waveguide section formed over a substrate, a quantum cascade laser (QCL) gain section formed over the substrate and adjacent to the passive waveguide section, and a taper section disposed between and in contact with each of the passive waveguide section and the QCL gain section. In some embodiments, the passive waveguide section includes a passive waveguide core layer disposed between a first cladding layer and a second cladding layer. In some examples, the QCL gain section includes a QCL active region disposed between a first confinement layer and a second confinement layer, where the QCL active region has a lower index of refraction than each of the first and second confinement layers. In some embodiments, the taper section is configured to optically couple the QCL gain section to the passive waveguide section.
FILED Tuesday, May 07, 2019
APPL NO 16/405827
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/1228 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 5/026 (20130101)
H01S 5/1014 (20130101)
H01S 5/1032 (20130101)
H01S 5/3401 (20130101)
H01S 5/3402 (20130101) Original (OR) Class
H01S 5/3406 (20130101)
H01S 5/34313 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11211800 Mohsenian-Rad et al.
FUNDED BY
Department of Energy (DOE)
Lawrence Livermore National Security LLC (LLNS)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California);  Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California);  LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
INVENTOR(S) Hamed Mohsenian-Rad (Riverside, California);  Mohammad Farajollahi (Riverside, California);  Alireza Shahsavari (Riverside, California);  Emma Mary Stewart (Danville, California)
ABSTRACT A method and system is disclosed for identifying a location of an event in a power distribution network. The method includes receiving voltage and current flowing downstream and upstream of the distribution feeder from at least two distribution-level phasor measurement units (PMUs) installed on a distribution feeder in the power distribution network; calculating changes in forward nodal voltages along the distribution feeder using measurements from at least one PMU of the at least two distribution-level PMUs; calculating changes in backward nodal voltages along the distribution feeder using the measurements from another PMU of the at least two distribution-level PMUs; comparing the calculated changes in the forward nodal voltages to the calculated changes in the backward nodal voltages; and determining the location of the event based on the comparison of the calculated changes of the forward nodal voltages to the calculated changes backward nodal voltages.
FILED Friday, June 07, 2019
APPL NO 16/435119
ART UNIT 2836 — Electrical Circuits and Systems
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 19/2513 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 3/02 (20130101)
H02J 3/46 (20130101) Original (OR) Class
H02J 3/1878 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11211913 Dong et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) The George Washington University (Washington, District of Columbia)
ASSIGNEE(S) The George Washington University (Washington, District of Columbia)
INVENTOR(S) Boqun Dong (Arlington, Virginia);  Mona Zaghloul (Washington, District of Columbia)
ABSTRACT A device employing the generation and enhancement of surface acoustic waves on a highly doped p-type III-V semiconductor substrate (e.g., GaAs, GaSb, InAs, or InGaAs). The device includes two SiO2/ZnO islands, each including a SiO2 buffer layer deposited on the doped p-type III-V semiconductor substrate and a ZnO layer deposited on the SiO2 buffer layer. An input interdigital transducers (IDT) and an output IDT are each patterned on one of the SiO2/ZnO islands. The IDTs generates surface acoustic waves along an exposed surface of the highly doped p-type III-V semiconductor substrate. The surface acoustic waves improve the photoelectric and photovoltaic properties of the device. The device is manufactured using a disclosed technique for propagating strong surface acoustic waves on weak piezoelectric materials. Also disclosed is a photodetector developed using that technique.
FILED Wednesday, July 15, 2020
APPL NO 16/929234
ART UNIT 2826 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 29/20 (20130101)
H01L 41/18 (20130101)

Impedance Networks, e.g Resonant Circuits; Resonators
H03H 9/02566 (20130101) Original (OR) Class
H03H 9/6426 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11212008 Brandt-Pearce et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
ASSIGNEE(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S) Maite Brandt-Pearce (Free Union, Virginia);  Jie Lian (Charlottesville, Virginia)
ABSTRACT A system and method for providing optical multiple input and multiple output data communication using optical signals includes a plurality of light sources, a plurality of photodetectors, and at least one controller. The plurality of light sources are configured to emit optical signals to communicate data. The plurality of photodetectors are configured to sense the optical signals, and are embedded in at least one receiver. At least one of the plurality of photodetectors is configured to receive the optical signals from two or more of the plurality of light sources. The controller is configured to assign a transmit power to at least some of the plurality of light sources based on parameters of the plurality of photodetectors.
FILED Thursday, May 09, 2019
APPL NO 16/407769
ART UNIT 2636 — Optical Communications
CURRENT CPC
Transmission
H04B 10/116 (20130101)
H04B 10/564 (20130101) Original (OR) Class
H04B 10/672 (20130101)
H04B 10/808 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 11207672 Lee et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Laboratory (LANL)
Los Alamos National Security, LLC (LANS)
National Science Foundation (NSF)
APPLICANT(S) RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York)
ASSIGNEE(S) Rensselaer Polytechnic Institute (Troy, New York)
INVENTOR(S) Sangwoo Lee (Cohoes, New York);  Chulsung Bae (Cohoes, New York);  Musashi J. Briem (Troy, New York);  Sungmin Park (Troy, New York)
ABSTRACT The anion exchange membranes exhibit enhanced chemical stability and ion conductivity when compared with traditional styrene-based alkaline anion exchange membranes. A copolymer backbone is polymerized from a reaction medium that includes a diphenylalkylene and an alkadiene. The copolymer includes a plurality of pendant phenyl groups. The diphenyl groups on the polymer backbone are functionalized with one or more haloalkylated precursor substrates. The terminal halide from the precursor substrate can then be substituted with a desired ionic group. The diphenylethylene-based alkaline anion exchange membranes lack the α-hydrogens sharing tertiary carbons with phenyl groups from polystyrene or styrene-based precursor polymers, resulting in higher chemical stability. The ionic groups are also apart from each other by about 3 to 6 carbons in the polymer backbone, enhancing ion conductivity. These membrane are advantageous for use in fuel cells, electrolyzers employing hydrogen, ion separations, etc.
FILED Tuesday, October 22, 2019
APPL NO 17/287639
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Separation
B01D 61/44 (20130101)
B01D 71/06 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 41/07 (20170101) Original (OR) Class
B01J 41/14 (20130101)
B01J 47/12 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/469 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 212/32 (20130101)
C08F 2810/00 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 5/2287 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207676 Saunders
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Marnie M. Saunders (Canton, Ohio)
ASSIGNEE(S) The University of Akron (Akron, Ohio)
INVENTOR(S) Marnie M. Saunders (Canton, Ohio)
ABSTRACT A lab-on-a-chip (LOC) for the biomimetic study of the multicellular interactions of bone cells includes a PDMS substrate and cap, which together form one or more wells that are fluidly coupled by tubes. The wells are configured to support various bone cells and related cellular support substrates therein, while the tubes allow conditioned medium (CM), including soluble signals, and various other co-factors to be communicated among the various wells. By controlling the configuration among and between various bone cells in the wells, the temporal and spatial limitations associated with traditional in vivo bone tissue models is removed. In addition, the LOC enables a particular research objective to be studied by allowing the user to configure the arrangement of the wells/tubes of the LOC, so as to control the manner in which bone cell soluble signals, bone cell contact, and bone cell matrix interaction interplay.
FILED Thursday, April 26, 2018
APPL NO 15/963360
ART UNIT 1799 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5027 (20130101) Original (OR) Class
B01L 3/502761 (20130101)
B01L 2300/16 (20130101)
B01L 2300/042 (20130101)
B01L 2300/163 (20130101)
B01L 2300/0829 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 21/08 (20130101)
C12M 23/12 (20130101)
C12M 23/16 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0068 (20130101)
C12N 5/0643 (20130101)
C12N 5/0654 (20130101)
C12N 2533/30 (20130101)
C12N 2533/54 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11207836 Ramos et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems (SPAWAR)
National Science Foundation (NSF)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Javier E. Ramos (Brookline, Massachusetts);  Pitchaya Sitthi-Amorn (Cambridge, Massachusetts);  Wojciech Matusik (Lexington, Massachusetts);  Yuwang Wang (Beijing, China PRC)
ABSTRACT The present application relates generally to systems and methods for using machine vision to provide information on one or more aspects of an additive fabrication device, such as calibration parameters and/or an object formed by the device or in the process of being formed by the device. According to some aspects, a method is provided for calibrating an additive fabrication device. According to some aspects, a method is provided for assessing at least a portion of an object formed using an additive fabrication device. According to some aspects, a method is provided for fabricating a second object in contact with a first object using an additive fabrication device. According to some aspects, an additive fabrication device configured to perform one or more of the above methods may be provided.
FILED Tuesday, July 30, 2019
APPL NO 16/526068
ART UNIT 1747 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/106 (20170801)
B29C 64/112 (20170801)
B29C 64/386 (20170801) Original (OR) Class
B29C 64/393 (20170801)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
B33Y 50/02 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208330 Nel et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
APPLICANT(S) The Regents of the University of California (Oakland, California);  Northwestern University (Evanston, Illinois)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  Northwestern University (Evanston, Illinois)
INVENTOR(S) Andre E. Nel (Sherman Oaks, California);  Tian Xia (Los Angeles, California);  Ruibin Li (Los Angeles, California);  Mark C. Hersam (Wilmette, Illinois);  Nikhita D. Mansukhani (Allston, Massachusetts);  Linda Guiney (Chicago, Illinois)
ABSTRACT In various embodiments functionalized graphene oxide(s) are provided that demonstrate improved antimicrobial activity, where the graphene oxide(s) are functionalized to increase carbon radical (.C) density.
FILED Wednesday, November 15, 2017
APPL NO 16/348862
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 43/90 (20130101)
A01N 59/00 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/08 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/198 (20170801) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208379 Grapperhaus et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (Louisville, Kentucky)
ASSIGNEE(S) UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (Louisville, Kentucky)
INVENTOR(S) Craig A. Grapperhaus (Jeffersonville, Indiana);  Robert M. Buchanan (Louisville, Kentucky);  Nicholas S. Vishnosky (Marlborough, Connecticut);  Jason O. E. Young (Owensboro, Kentucky);  Paula J. Bates (Louisville, Kentucky);  Sarah A. Andres (Floyds Knobs, Indiana);  Caleb Aaron Calvary (Louisville, Kentucky)
ABSTRACT Some embodiments of the invention include inventive compounds (e.g., compounds of Formula (I) or (Ia)). Other embodiments include compositions (e.g., pharmaceutical compositions) comprising the inventive compound. Still other embodiments of the invention include compositions (e.g., pharmaceutical compositions) for treating, for example, certain diseases using the inventive compounds. Some embodiments include methods of using the inventive compound (e.g., in compositions or in pharmaceutical compositions) for administering and treating (e.g., diseases such as cancer). Further embodiments include methods for making the inventive compounds. Additional embodiments of the invention are also discussed herein.
FILED Sunday, November 03, 2019
APPL NO 16/672481
ART UNIT 1699 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Acyclic or Carbocyclic Compounds
C07C 335/40 (20130101) Original (OR) Class

Heterocyclic Compounds
C07D 265/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208394 Dauenhauer et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Paul J. Dauenhauer (Shoreview, Minnesota);  Daniel J. Lundberg (Minneapolis, Minnesota);  David J. Lundberg (Minneapolis, Minnesota);  Marc A. Hillmyer (Minneapolis, Minnesota)
ABSTRACT Synthesizing an alkyl-caprolactone includes hydrogenating an alkyl-phenol to yield a first mixture comprising an alkyl-cyclohexanone and an alkyl-cyclohexanol; separating the alkyl-cyclohexanone from the first mixture to yield a first portion of a purified alkyl-cyclohexanone; oxidizing the first portion of the purified alkyl-cyclohexanone to yield a second mixture comprising an alkyl-caprolactone, the alkyl-cyclohexanone, and the alkyl-cyclohexanol; separating the alkyl-caprolactone from the second mixture to yield a third mixture comprising the alkyl-cyclohexanone and the alkyl-cyclohexanol; combining the third mixture and the first mixture in to yield a fourth mixture; separating the alkyl-cyclohexanone from the fourth mixture to yield a second portion of the purified alkyl-cyclohexanone; oxidizing the second portion of the purified alkyl-cyclohexanone to yield a fifth mixture comprising the alkyl-caprolactone, the alkyl-cyclohexanone, and the alkyl-cyclohexanol; separating the alkyl-caprolactone from the fifth mixture; and combining the alkyl-caprolactone from the fifth mixture with the alkyl-caprolactone from the second mixture.
FILED Friday, September 06, 2019
APPL NO 16/562971
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 313/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208534 Guan
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Zhibin Guan (Irvine, California)
ABSTRACT The disclosure provides for dynamic polymers based on silyl ether exchange that are malleable and recyclable which have favorable mechanical properties and chemical resistance, methods of making thereof, and uses and applications thereof.
FILED Tuesday, June 26, 2018
APPL NO 16/019500
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 8/44 (20130101)
C08F 8/44 (20130101)
C08F 12/22 (20130101)
C08F 12/24 (20130101)
C08F 12/24 (20130101)
C08F 212/08 (20130101)
C08F 212/08 (20130101)
C08F 212/14 (20130101)
C08F 212/24 (20200201)
C08F 216/06 (20130101)
C08F 220/20 (20130101)
C08F 230/08 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 3/24 (20130101) Original (OR) Class
C08J 2325/18 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 5/5415 (20130101)

Compositions of Macromolecular Compounds
C08L 2312/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208571 Wang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) University of Maryland, College Park (College Park, Maryland)
ASSIGNEE(S) UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland)
INVENTOR(S) YuHuang Wang (Laurel, Maryland);  Peng Wang (Rockville, Maryland);  Mijin Kim (New York, New York);  Chiyu Zhang (Berwyn Heights, Maryland)
ABSTRACT A method termed “superacid-surfactant exchange” (S2E) for the dispersion of carbon nanomaterials in aqueous solutions. This S2E method enables nondestructive dispersion of carbon nanomaterials (including single-walled carbon nanotubes, double-walled carbon nanotubes, multi-wall carbon nanotubes, and graphene) at rapidly and at large scale in aqueous solution without a requirement for expensive or complicated equipment. Dispersed carbon nanotubes obtained from this method feature long length, low defect density, high electrical conductivity, and in the case of semiconducting single-walled carbon nanotubes, bright photoluminescence in the near-infrared.
FILED Thursday, August 08, 2019
APPL NO 16/536166
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 32/19 (20170801)
C01B 32/21 (20170801)
C01B 32/156 (20170801)
C01B 32/159 (20170801)
C01B 32/172 (20170801)
C01B 32/174 (20170801)
C01B 32/194 (20170801)
C01B 2202/02 (20130101)
C01B 2202/04 (20130101)
C01B 2202/06 (20130101)
C01B 2202/22 (20130101)
C01B 2202/28 (20130101)
C01B 2202/34 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 11/037 (20130101)
C09D 11/52 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208628 Strano et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
APPLICANT(S) Michael S. Strano (Lexington, Massachusetts);  Juan Pablo Giraldo Gomez (Somerville, Massachusetts);  Sean Mitchell Faltermeier (Cambridge, Massachusetts);  Markita P. Landry (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) Michael S. Strano (Lexington, Massachusetts);  Juan Pablo Giraldo Gomez (Somerville, Massachusetts);  Sean Mitchell Faltermeier (Cambridge, Massachusetts);  Markita P. Landry (Cambridge, Massachusetts)
ABSTRACT In one aspect, a composition can include an organelle, and a nanoparticle having a zeta potential of less than −10 mV or greater than 10 mV contained within the organelle. In a preferred embodiment, the organelle can be a chloroplast and the nanoparticle can be a single-walled carbon nanotube associated with a strongly anionic or strongly cationic polymer.
FILED Thursday, August 07, 2014
APPL NO 14/454196
ART UNIT 1663 — Plants
CURRENT CPC
New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques
A01H 3/00 (20130101)
A01H 5/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/04 (20130101) Original (OR) Class
C12N 15/87 (20130101)
C12N 15/8207 (20130101)
C12N 15/8212 (20130101)
C12N 15/8214 (20130101)
C12N 15/8269 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11208676 Xuan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Feng Xuan (Boston, Massachusetts);  Peng Yin (Brookline, Massachusetts);  Mingjie Dai (Brookline, Massachusetts);  Xi Chen (West Newton, Massachusetts)
ABSTRACT The present disclosure provides, in some embodiments, methods and compositions for single-molecule detection.
FILED Friday, May 26, 2017
APPL NO 16/304323
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6804 (20130101) Original (OR) Class
C12Q 1/6804 (20130101)
C12Q 2525/186 (20130101)
C12Q 2525/301 (20130101)
C12Q 2531/119 (20130101)
C12Q 2565/514 (20130101)

Combinatorial Chemistry; Libraries, e.g Chemical Libraries
C40B 70/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209383 Seker et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Erkin Seker (Davis, California);  Joshua Hihath (Woodland, California);  Maria Marco (Davis, California);  Paul Feldstein (Sacramento, California);  Pallavi Daggumati (Emeryville, California);  Yuanhui Li (Davis, California);  Zimple Matharu (Davis, California);  Juan Artes Vivancos (Amstelveen, Netherlands)
ABSTRACT A biosensor platform apparatus and method are provided that can detect, purify and identify nucleic acid (DNA and RNA) biomarkers in complex biological fluids. The methods use a two-stage molecular based approach. The first stage screens for specific nucleic acid-based biomarkers in complex biological fluids by electrochemical detection of DNA:RNA hybridization and facilitates the removal of remaining complex media constituents. The first stage utilizes probes within a tunable nanoporous electrode. The second stage identifies the purified specific hybrids by single-molecule conductance measurements via break junction scanning. Identification can be assisted with a library of conductance measurements. The methods can provide strain level information that can be used for identifying anti-microbial resistance in detected pathogens. Collection of RNA targets allows for biomarker detection and identification without the need for amplification and can provide information about the viability of the sample organism.
FILED Wednesday, October 31, 2018
APPL NO 16/176877
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6825 (20130101)
C12Q 1/6825 (20130101)
C12Q 1/6834 (20130101)
C12Q 1/6834 (20130101)
C12Q 2563/116 (20130101)
C12Q 2563/116 (20130101)
C12Q 2565/519 (20130101)
C12Q 2565/519 (20130101)
C12Q 2565/607 (20130101)
C12Q 2565/629 (20130101)
C12Q 2565/629 (20130101)
C12Q 2565/631 (20130101)
C12Q 2565/631 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/26 (20130101)
G01N 27/3276 (20130101) Original (OR) Class
G01N 27/3277 (20130101)
G01N 27/44791 (20130101)
G01N 33/483 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209454 Fu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Kevin Fu (Ann Arbor, Michigan);  Peter Honeyman (Ann Arbor, Michigan);  Timothy Trippel (Ann Arbor, Michigan);  Ofir Weisse (Ann Arbor, Michigan)
ABSTRACT Cyber-physical systems depend on sensors to make automated decisions. Resonant acoustic injection attacks are already known to cause malfunctions by disabling MEMS-based gyroscopes. However, an open question remains on how to move beyond denial of service attacks to achieve full adversarial control of sensor outputs. This work investigates how analog acoustic injection attacks can damage the digital integrity of a popular type of sensor: the capacitive MEMS accelerometer. Spoofing such sensors with intentional acoustic interference enables an out-of-spec pathway for attackers to deliver chosen digital values to microprocessors and embedded systems that blindly trust the unvalidated integrity of sensor outputs. Two software-based solutions are presented for mitigating acoustic interference with output of a MEMS accelerometer and other types of motion sensors.
FILED Friday, May 19, 2017
APPL NO 16/303495
ART UNIT 2862 — Printing/Measuring and Testing
CURRENT CPC
Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement
G01P 13/00 (20130101) Original (OR) Class
G01P 15/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209469 Liu et al.
FUNDED BY
Department of Energy (DOE)
UT-Battelle, LLC (UT-BATTELLE)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) University of Tennessee Research Foundation (Knoxville, Tennessee)
ASSIGNEE(S) UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee);  UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Yilu Liu (Knoxville, Tennessee);  Wenpeng Yu (Knoxville, Tennessee);  Wenxuan Yao (Knoxville, Tennessee)
ABSTRACT A method includes performing by a processor: receiving a plurality of synchrophasor measurements of a power system signal associated with a time interval from a phasor measurement unit (PMU), each of the plurality of synchrophasor measurements including a phase angle, frequency value, and a timestamp associated with the synchrophasor measurement, determining a plurality of relative phase angles based on the plurality of phase angles, determining a correlation coefficient between the plurality of relative phase angles and a plurality of corresponding frequency values of the power system signal, and detecting an error in the plurality of timestamps based on the correlation coefficient; estimating the error in the plurality of timestamps based on the plurality of relative phase angles and the plurality of corresponding frequency values.
FILED Tuesday, May 21, 2019
APPL NO 16/418540
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 19/2513 (20130101)
G01R 25/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209536 Joshi et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California)
ASSIGNEE(S) THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California)
INVENTOR(S) Kiran Joshi (Sunnyvale, California);  Dinesh Bharadia (Menlo Park, California);  Sachin Katti (Stanford, California);  Manikanta Kotaru (Stanford, California)
ABSTRACT Techniques for a motion tracing device using radio frequency signals are presented. The motion tracing device utilizes radio frequency signals, such as WiFi to identify moving objects and trace their motion. Methods and apparatus are defined that can measure multiple WiFi backscatter signals and identify the backscatter signals that correspond to moving objects. In addition, motion of a plurality of moving objects can be detected and traced for a predefined duration of time.
FILED Monday, May 04, 2015
APPL NO 15/307721
ART UNIT 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 13/56 (20130101) Original (OR) Class
G01S 13/87 (20130101)
G01S 13/538 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209716 Valentine et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) Vanderbuilt University (Nashville, Tennessee)
INVENTOR(S) Jason G. Valentine (Nashville, Tennessee);  Richard F. Haglund (Nashville, Tennessee);  Zhihua Zhu (Nashville, Tennessee);  Austin Howes (Nashville, Tennessee)
ABSTRACT According to some aspects, a transmissive and all-dielectric optical component/limiter with great cutoff efficiency using Vanadium Dioxide (VO2) as the active component is disclosed. In some embodiments, Vanadium dioxide is used for an optical limiter due to the large contrast in optical constants upon undergoing the semiconductor to metal phase transition. When triggered optically, this transition occurs within 60 fs, making the device suitable for an ultrafast laser environment. In addition, the phase transition threshold is tunable by applying stress or doping; therefore, the device cutoff intensity can be adjusted to fulfill specific requirements.
FILED Friday, October 04, 2019
APPL NO 16/593551
ART UNIT 2874 — Optics
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/3501 (20130101)
G02F 1/3507 (20210101)
G02F 1/3509 (20210101)
G02F 1/3523 (20130101) Original (OR) Class
G02F 1/3556 (20130101)
G02F 1/3558 (20130101)
G02F 2202/30 (20130101)
G02F 2203/15 (20130101)
G02F 2203/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11210428 Zhu et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana)
ASSIGNEE(S) THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana)
INVENTOR(S) Ruiyu Zhu (Bloomington, Indiana);  Yan Huang (Greenwood, Indiana)
ABSTRACT Technologies are disclosed herein for running a long-term on-demand service for executing actively-secure computations. A function circuit may be represented as a stream of buckets, in which each bucket represents a logical AND gate. A pool having a plurality of garbled AND gates is generated. Garbled AND gates are randomly selected from the pool for placement in one of the buckets. An output for the bucket is determined by an evaluation of the selected garbled AND gates. The output represents an execution of the logical AND gate. The determined output is applied as a parameter in a secure protocol.
FILED Thursday, June 06, 2019
APPL NO 16/433455
ART UNIT 2492 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 9/541 (20130101)
G06F 11/00 (20130101)
G06F 12/14 (20130101)
G06F 21/72 (20130101) Original (OR) Class
G06F 21/602 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11210747 Frolik et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) University of Vermont and State Agricultural College (Burlington, Vermont)
ASSIGNEE(S) University of Vermont and State Agricultural College (Burlington, Vermont)
INVENTOR(S) Jeff Frolik (Burlington, Vermont);  Paul Hines (Burlington, Vermont);  Mads Almassalkhi (Burlington, Vermont)
ABSTRACT The present disclosure provides a distributed and anonymous approach to demand response of an electricity system. The approach conceptualizes energy consumption and production of distributed-energy resources (DERs) via discrete energy packets that are coordinated by a cyber computing entity that grants or denies energy packet requests from the DERs. The approach leverages a condition of a DER, which is particularly useful for (1) thermostatically-controlled loads, (2) non-thermostatic conditionally-controlled loads, and (3) bi-directional distributed energy storage systems. In a first aspect of the present approach, each DER independently requests the authority to switch on for a fixed amount of time (i.e., packet duration). The coordinator determines whether to grant or deny each request based electric grid and/or energy or power market conditions. In a second aspect, bi-directional DERs, such as distributed-energy storage systems (DESSs) are further able to request to supply energy to the grid.
FILED Thursday, September 21, 2017
APPL NO 15/712089
ART UNIT 2119 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electric Digital Data Processing
G06F 17/18 (20130101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 50/06 (20130101) Original (OR) Class

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 3/00 (20130101)
H02J 3/003 (20200101)
H02J 3/14 (20130101)
H02J 13/00 (20130101)

Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications
Y02B 70/3225 (20130101)

Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids
Y04S 20/222 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11211091 Singer et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio);  FOLIO PHOTONICS, INC. (Solon, Ohio)
INVENTOR(S) Kenneth D. Singer (Pepper Pike, Ohio);  Irina Shiyanovskaya (Cleveland, Ohio)
ABSTRACT An optical information storage medium includes a substrate and a multilayer polymeric film. The multilayer polymeric film has a first surface and an opposite second surface that extend the length of the multilayer polymeric film. The second surface is adhered to a surface of the substrate. The multilayer polymeric film includes a plurality of coextruded alternating polymeric active data storage layers and polymeric buffer layers.
FILED Tuesday, March 12, 2019
APPL NO 16/351166
ART UNIT 1737 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Information Storage Based on Relative Movement Between Record Carrier and Transducer
G11B 7/26 (20130101)
G11B 7/0052 (20130101)
G11B 7/0079 (20130101)
G11B 7/242 (20130101)
G11B 7/245 (20130101)
G11B 7/24027 (20130101)
G11B 7/24038 (20130101) Original (OR) Class
G11B 7/24044 (20130101)
G11B 7/24056 (20130101)
G11B 7/24065 (20130101)
G11B 2007/0013 (20130101)
G11B 2007/24624 (20130101)
G11B 2007/240025 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11211525 Rajan et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Ohio State Innovation Foundation (Columbus, Ohio)
ASSIGNEE(S) Ohio State Innovation Foundation (Columbus, Ohio)
INVENTOR(S) Siddharth Rajan (Columbus, Ohio);  Yuewei Zhang (Columbus, Ohio);  Zane Jamal-Eddine (Columbus, Ohio);  Fatih Akyol (Corum/Merkez, Turkey)
ABSTRACT An example tunnel junction ultraviolet (UV) light emitting diode (LED) is described herein. The UV LED can include a mesa structure having at least one of: an n-doped bottom contact region, a p-doped region, and a tunnel junction arranged in contact with the p-doped region. Additionally, a geometry of the mesa structure can be configured to increase respective efficiencies of extracting transverse-electric (TE) polarized light and transverse-magnetic (TM) polarized light from the tunnel junction UV LED. The mesa structure can be configured such that an emitted photon travels less than 10 μm before reaching the inclined sidewall.
FILED Tuesday, May 01, 2018
APPL NO 16/610158
ART UNIT 2816 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 33/06 (20130101)
H01L 33/20 (20130101) Original (OR) Class
H01L 33/32 (20130101)
H01L 33/385 (20130101)
H01L 33/405 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11211569 Jurchescu et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) Wake Forest University (Winston-Salem, North Carolina)
ASSIGNEE(S) WAKE FOREST UNIVERSITY (Winston-Salem, North Carolina)
INVENTOR(S) Oana Diana Jurchescu (Winston-Salem, North Carolina);  Peter James Diemer (Mocksville, North Carolina)
ABSTRACT Organic semiconductor compositions (OSCs) compatible with laser printing techniques are described herein. In being compatible with laser printing techniques, the OSCs are in particulate form and generally comprise an organic semiconductor component and carrier. The organic semiconductor component can comprise any small molecule semiconductor or polymeric semiconductor not inconsistent with the laser printing methods.
FILED Monday, January 30, 2017
APPL NO 16/073643
ART UNIT 2899 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 51/0004 (20130101)
H01L 51/0013 (20130101)
H01L 51/0026 (20130101)
H01L 51/0055 (20130101)
H01L 51/0074 (20130101) Original (OR) Class
H01L 51/0094 (20130101)
H01L 51/0097 (20130101)
H01L 51/0558 (20130101)
H01L 51/0566 (20130101)
H01L 51/4253 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/549 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11212173 Narayanan et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) AT and T Intellectual Property I, L.P. (Atlanta, Georgia);  The Research Foundation For The State University of New York (Albany, New York)
ASSIGNEE(S) AT and T Intellectual Property I, L.P. (Atlanta, Georgia);  The Research Foundation for the State University of New York (Albany, New York)
INVENTOR(S) Shankaranarayanan Puzhavakath Narayanan (Hillsborough, New Jersey);  Bharath Balasubramanian (Princeton, New Jersey);  Gueyoung Jung (Belle Mead, New Jersey);  Muhammad Wajahat (Stony Brook, New York);  Anshul Gandhi (Westbury, New York)
ABSTRACT A system that determines whether a trigger has occurred within a cloud infrastructure. The system, in response to determining that a trigger has occurred, extracts characteristics from one or more virtual network functions (VNFs) of a service chain. The system, in response to extracting characteristics from the one or more VNFs, determines rehoming actions for each of the one or more VNFs. The system, in response to determining rehoming actions, predicts a rehoming delay or a chain downtime for each of the rehoming actions for each of the one or more VNFs. The system determines an optimal rehoming action from the rehoming actions for at least one of the one or more VNFs using the rehoming delay or the chain downtime for each rehoming action of the rehoming actions. The system performs the optimal rehoming action for the at least one of one or more VNFs.
FILED Thursday, December 12, 2019
APPL NO 16/712594
ART UNIT 2457 — Computer Networks
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 41/0816 (20130101) Original (OR) Class
H04L 67/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11212479 Gollakota et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Shyamnath Gollakota (Seattle, Washington);  Saman Naderiparizi (Seattle, Washington);  Mehrdad Hessar (Seattle, Washington);  Vamsi Talla (Seattle, Washington);  Joshua R. Smith (Seattle, Washington)
ABSTRACT Examples described herein include systems, devices, and methods for backscattering carrier signals in accordance with pixel values of an image and/or video. Signals having a property proportionate to pixel values may be converted into a pulse-containing waveform having pulses whose widths and/or duty cycles are determined based on the pixel values. Backscatter transmitters may backscatter a carrier signal in accordance with the pulse-containing waveform to provide the pixel values to a receiver. In this manner, video transmission at low power and/or battery-free operation may be provided.
FILED Friday, April 06, 2018
APPL NO 16/603195
ART UNIT 2422 — Cable and Television
CURRENT CPC
Pictorial Communication, e.g Television
H04N 5/40 (20130101) Original (OR) Class
H04N 5/44 (20130101)
H04N 5/335 (20130101)
H04N 7/045 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 11208217 Valinia et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) Azita Valinia (Greenbelt, Maryland);  Irving Burt (Greenbelt, Maryland);  Bruce Pham (Greenbelt, Maryland);  Opher Ganel (Greenbelt, Maryland)
ABSTRACT In at least one aspect, a small satellite includes a cylindrical body, a predetermined payload volume, a payload adapter ring mechanical interface for interchangeably mechanically coupling to a launch vehicle payload adapter ring, an electrical interface specifying a set of electrical specifications for interchangeably electrically coupling to the launch vehicle payload adapter ring, a specified center of gravity location and specified frequency response, where the predetermined payload volume, payload adapter ring mechanical interface, electrical interface, specified center of gravity location, and frequency response range allow the small satellite to be interchanged with other small satellites when coupling to the launch vehicle.
FILED Tuesday, March 31, 2020
APPL NO 16/835366
ART UNIT 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Cosmonautics; Vehicles or Equipment Therefor
B64G 1/10 (20130101) Original (OR) Class
B64G 1/428 (20130101)
B64G 1/641 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209858 Mautner et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Johnson Space Center (JSC)
APPLICANT(S) THE CHARLES STARK DRAPER LABORATORY, INC. (Cambridge, Massachusetts)
ASSIGNEE(S) THE CHARLES STARK DRAPER LABORATORY, INC. (Cambridge, Massachusetts)
INVENTOR(S) Eric Karl Mautner (Hudson, Massachusetts);  Brianna Klingensmith (Arlington, Massachusetts)
ABSTRACT The present disclosure relates to systems and methods to maintain clock synchronization of multiple computers, or computer systems, through the exchange of communication messages that include clock and/or timing information.
FILED Thursday, July 25, 2019
APPL NO 16/522151
ART UNIT 2186 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 1/12 (20130101)
G06F 1/14 (20130101) Original (OR) Class
G06F 13/122 (20130101)

Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses
H03L 7/0814 (20130101)
H03L 7/0991 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 7/0025 (20130101)
H04L 7/0037 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US PP33787 Hokanson et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
INVENTOR(S) Stanley Hokanson (North Oaks, Minnesota);  Steven Thomas McNamara (Victoria, Minnesota)
ABSTRACT A new cultivar of hybrid Rhododendron plant named ‘UMNAZ633’ that is characterized by its rounded plant form with compactly branched plant habit; reaching 1 m in height and width after 15 years of growth, its abundance of flowers that are red in color in mid to late May in Excelsior, Minn. with the red color retained throughout the bloom period without substantial fading prior to abscission, its good cold hardiness with flower buds that are resistant to cold damage and consistently bloom even when exposed to temperatures as low as −25°, and its foliage with relatively good tolerance to powdery mildew.
FILED Thursday, April 08, 2021
APPL NO 17/225284
ART UNIT 1661 — Plants
CURRENT CPC
New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques
A01H 6/364 (20180501) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 11209314 Fleisher et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland)
ASSIGNEE(S) GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland)
INVENTOR(S) Adam Joseph Fleisher (Gaithersburg, Maryland);  Keith Alan Gillis (Washington Grove, Maryland);  Joseph Terence Hodges (Washington Grove, Maryland)
ABSTRACT A cavity buildup dispersion spectrometer includes a shutter that modulates coherent electromagnetic radiation at a shutter frequency; and produces modulated electromagnetic radiation; a frequency shifter that frequency shifts the modulated electromagnetic radiation to a shifter frequency and produces frequency shifted radiation; a resonator that produces cavity radiation from the frequency shifted radiation and the coherent electromagnetic radiation, receives an analyte; subjects the analyte to cavity radiation, and transmits the cavity radiation as transmitted electromagnetic radiation; and a receiver that: produces a detector signal from the transmitted electromagnetic radiation, such that the detector signal includes a beat frequency that corresponds to a change in a motion of resonator that includes a change in the distance between the mirrors or a change of refractive index of the analyte in the intracavity space.
FILED Friday, December 18, 2020
APPL NO 17/126118
ART UNIT 2886 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/10 (20130101)
G01J 3/12 (20130101)
G01J 3/021 (20130101)
G01J 3/0232 (20130101)
G01J 3/4338 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Office of the Director of National Intelligence (ODNI) 

US 11210806 Qian et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) ObjectVideo Labs, LLC (Tysons, Virginia)
ASSIGNEE(S) ObjectVideo Labs, LLC (Tysons, Virginia)
INVENTOR(S) Gang Qian (McLean, Virginia);  Yunxian Zhou (Herndon, Virginia);  David Conger (Sterling, Virginia);  Allison Beach (Leesburg, Virginia)
ABSTRACT Methods and apparatus are disclosed for enhancing urban surface model with image data obtained from a satellite image. Three dimensional models of an urban cityscape obtained from digital surface models may comprise surface location information but lack image information associated with the cityscape, such as the color and texture of building facades. The location of the satellite at the time of recording the satellite image interest may be obtained from metadata associated with the satellite image. A 3D model of a cityscape corresponding to the satellite image may be subjected to a transformation operation to determine portions of the 3D model that are viewable from a location corresponding to the location of the satellite when taking the picture. Visible facades buildings of the 3D model ma be identified and mapped to portions of the satellite image which may then be used in rendering 2D images from the 3D model. In some examples a satellite image projection model may be adjusted to more accurately determine geolocations of portions of the satellite image by analysis of a plurality of satellite images.
FILED Wednesday, August 21, 2019
APPL NO 16/546393
ART UNIT 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Image Data Processing or Generation, in General
G06T 7/60 (20130101) Original (OR) Class
G06T 15/04 (20130101)
G06T 2207/10032 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 11209166 Vallejo Ruiz et al.
FUNDED BY
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Ernesto Andres Vallejo Ruiz (Cincinnati, Ohio);  Aaron Michael Dziech (Crittenden, Kentucky);  Jonathon Eli Farmer (Newport, Kentucky)
ABSTRACT A combustor assembly for a gas turbine engine defining a radial direction and a circumferential direction includes a liner assembly at least partially defining a combustion chamber and including at least one liner extending between a downstream end and an upstream end, the downstream end of the at least one liner defining a radial opening and an interface surface extending along the circumferential direction and along the radial direction; and a seal member including a body, a flange, and a radial element, the body defining a body surface extending along the radial direction and positioned adjacent the interface surface of the at least one liner, the flange extending forward from the body, and the radial element coupled to the flange and extending into the radial opening defined by the at least one liner.
FILED Wednesday, December 05, 2018
APPL NO 16/210385
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 9/023 (20130101)

Jet-propulsion Plants
F02K 1/82 (20130101)

Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers
F23R 3/007 (20130101)
F23R 3/60 (20130101) Original (OR) Class
F23R 2900/00012 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11209849 Hsia et al.
FUNDED BY
APPLICANT(S) Timothy T. Hsia (Irvine, California);  Victor K. Lee (Irvine, California)
ASSIGNEE(S) NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia)
INVENTOR(S) Timothy T. Hsia (Irvine, California);  Victor K. Lee (Irvine, California)
ABSTRACT A circuit includes a regulation module having a threshold input to receive a clamp threshold voltage and a feedback input to monitor a swing-limited output voltage. The regulation module generates a difference signal that indicates a difference between the clamp threshold voltage and the swing-limited output voltage. A current compensation module includes a clamp port and an input port. The clamp port to controls the swing-limited output voltage and the input port receives the difference signal. The clamp port generates an adjustment current to control the swing-limited output voltage based on the difference signal. An adjustment network receives an input voltage and the adjustment current from the clamp port. The adjustment current to generate a voltage across the adjustment network such that the swing-limited output voltage at the clamp port is adjusted within a voltage range of the input voltage.
FILED Friday, September 06, 2019
APPL NO 16/563023
ART UNIT 2838 — Electrical Circuits and Systems
CURRENT CPC
Systems for Regulating Electric or Magnetic Variables
G05F 1/575 (20130101) Original (OR) Class
G05F 1/625 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, December 28, 2021.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2021/details-patents-20210427.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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