FedInvent™ Patent Applications
Application Details for Thursday, January 06, 2022
This page was updated on Friday, January 07, 2022 at 06:40 PM GMT
Department of Health and Human Services (HHS)
| US 20220000084 | Stevens et al. |
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| FUNDED BY |
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| APPLICANT(S) | Regeneron Pharmaceuticals, Inc. (Tarrytown, New York); Yale University (New Haven, Connecticut); Institute for Research in Biomedicine (IRB) (Bellinzona, Switzerland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sean Stevens (Del Mar, California); Andrew J. Murphy (Croton-on-Hudson, New York); Richard Flavell (Guilford, Connecticut); Elizabeth Eynon (New Haven, Connecticut); Jorge Galan (New Haven, Connecticut); Tim Willinger (Ultran, Sweden); Markus Manz (Zollikon, Switzerland); Anthony Rongvaux (New Haven, Connecticut); George D. Yancopoulos (Yorktown Heights, New York) |
| ABSTRACT | A mouse with a humanization of the mIL-3 gene and the mGM-CSF gene, a knockout of a mRAG gene, and a knockout of a mIl2rg subunit gene; and optionally a humanization of the TPO gene is described. A RAG/Il2rg KO/hTPO knock-in mouse is described. A mouse engrafted with human hematopoietic stem cells (HSCs) that maintains a human immune cell (HIC) population derived from the HSCs and that is infectable by a human pathogen, e.g., S. typhi or M. tuberculosis is described. A mouse that models a human pathogen infection that is poorly modeled in mice is described, e.g., a mouse that models a human mycobacterial infection, wherein the mouse develops one or more granulomas comprising human immune cells. A mouse that comprises a human hematopoietic malignancy that originates from an early human hematopoietic cells is described, e.g., a myeloid leukemia or a myeloproliferative neoplasia. |
| FILED | Wednesday, June 09, 2021 |
| APPL NO | 17/343294 |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0271 (20130101) A01K 67/0275 (20130101) A01K 67/0278 (20130101) Original (OR) Class A01K 2207/12 (20130101) A01K 2207/15 (20130101) A01K 2217/15 (20130101) A01K 2217/072 (20130101) A01K 2217/075 (20130101) A01K 2227/105 (20130101) A01K 2267/03 (20130101) A01K 2267/0331 (20130101) A01K 2267/0337 (20130101) A01K 2267/0381 (20130101) A01K 2267/0387 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/00 (20130101) Peptides C07K 14/524 (20130101) C07K 14/535 (20130101) C07K 14/5403 (20130101) C07K 14/7155 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220000103 | Benfey et al. |
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| FUNDED BY |
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| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Philip Benfey (Durham, North Carolina); Alexandra Dickinson (Durham, North Carolina) |
| ABSTRACT | This disclosure relates to methods of regulating growth in a plant. Specifically, the methods of the disclosure regulate growth of the plant by administration of a composition comprising an effective amount of one or more apocarotenoids to the plant, its part, or the seed. |
| FILED | Saturday, November 09, 2019 |
| APPL NO | 17/291992 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 31/02 (20130101) A01N 31/04 (20130101) A01N 33/02 (20130101) Original (OR) Class A01N 37/06 (20130101) A01N 37/08 (20130101) A01N 43/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220000118 | Melander et al. |
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| FUNDED BY |
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| APPLICANT(S) | NORTH CAROLINA STATE UNIVERSITY (Raleigh, North Carolina); AGILE SCIENCES, INC. (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christian Melander (Raleigh, North Carolina); David Kendall Jung (Durham, North Carolina); Samuel Onofre Reyes (Cary, North Carolina) |
| ABSTRACT | Provided are 2-aminoimidazole-phenyl derivative compounds of Formula (I): which compounds are useful in methods of controlling microbial growth, such as by enhancing the effects of an antibiotic administered in combination with the compound. Compositions including these compounds, devices including these compounds, and methods of using the same are also provided. |
| FILED | Thursday, March 08, 2018 |
| APPL NO | 16/492722 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 47/30 (20130101) Original (OR) Class A01N 47/32 (20130101) A01N 47/36 (20130101) Biocidal, Pest Repellant, Pest Attractant or Plant Growth Regulatory Activity of Chemical Compounds or Preparations A01P 1/00 (20210801) Preparations for Medical, Dental, or Toilet Purposes A61K 31/4168 (20130101) A61K 31/4178 (20130101) A61K 31/4184 (20130101) A61K 31/4439 (20130101) A61K 31/5377 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/232 (20130101) A61L 2202/24 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Heterocyclic Compounds C07D 233/88 (20130101) C07D 235/30 (20130101) C07D 401/12 (20130101) C07D 403/12 (20130101) C07D 405/12 (20130101) C07D 409/12 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220000119 | Koo et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Hyun Koo (Philadelphia, Pennsylvania); Kathleen Stebe (Penn Valley, Pennsylvania); Vijay Kumar (Wilmington, Delaware); Elizabeth Hunter (Philadelphia, Pennsylvania); Edward Steager (Media, Pennsylvania); Evan Brink (Philadelphia, Pennsylvania) |
| ABSTRACT | Systems and methods for eradicating biofilms by killing bacteria within a biofilm, degrading the matrix and removing biofilm debris are disclosed herein. The disclosed subject matter provides techniques for administering a suspension of H2O2 and iron oxide nanoparticles to substantially eradicate bacteria within a biofilm matrix and degrade the bio film matrix, actuating the iron oxide nanoparticles for assembly into biohybrid robots suitable for removal of biofilm debris, and moving the biohybrid robots to remove the bio film debris from accessible or enclosed surfaces. In some embodiments, the disclosed subject matter can include embedding iron oxide nanoparticles in a hydrogel to form a soft robotic structure, administering the soft robotic structure to a biofilm-covered location, and magnetizing the soft robot structure to substantially eradicate bacteria within a biofilm matrix, degrade the biofilm matrix, and remove biofilm debris from enclosed surfaces. |
| FILED | Monday, November 25, 2019 |
| APPL NO | 17/291326 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/04 (20130101) A01N 59/16 (20130101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 6/52 (20200101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 25/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2454 (20130101) Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 7/017 (20210801) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220000588 | TAPALTSYAN et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF CENTRAL OKLAHOMA (Edmond, Oklahoma) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vagan TAPALTSYAN (El Cerrito, California); Morshed KHANDAKER (Edmond, Oklahoma); Shahram RIAHINEZHAD (Fort Lee, New Jersey); Rami Mohanad Mahdi ALKHALEELI (Edmond, Oklahoma); Niyaf Nidhal Kadhem ALKADHEM (Edmond, Oklahoma) |
| ABSTRACT | The present invention enables modification of an intraosseous implant device that is not only biologically non-inert, but can stimulate bone and vascular growth; decrease localized inflammation; and fight local infections. The method of the present invention provides a fiber with any of the following modifications: (1) Nanofiber with PDGF, (2) Nanofiber with PDGF+BMP2, and (3) Nanofiber with BMP2 and Ag. Nanofiber can be modified with other growth factors that have been shown to improve bone growth and maturation—BMP and PDGF being the most common. Nanofiber can be applied on the surface of the implant in several ways. First, a spiral micro-notching can be applied on the implant in the same direction as the threads with the nanofibers embedded into the notches. Second, the entire surface of the implant may be coated with a mesh of nanofibers. Third, it can be a combination of both embedding and notching. |
| FILED | Wednesday, September 15, 2021 |
| APPL NO | 17/476182 |
| CURRENT CPC | Dentistry; Apparatus or Methods for Oral or Dental Hygiene A61C 8/0006 (20130101) Original (OR) Class A61C 8/0013 (20130101) A61C 8/0016 (20130101) A61C 8/0022 (20130101) A61C 13/0018 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 6/891 (20200101) A61K 6/898 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220000703 | Lerner et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of Northern Arizona University (Flagstaff, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zachary F. Lerner (Flagstaff, Arizona); James Babers (Flagstaff, Arizona) |
| ABSTRACT | A foot plate for an assistive device is disclosed. The foot plate includes a planar vertical mounting portion on its lateral side, and a planar foot bed. The foot plate includes a gradual shoulder portion, such as a web of material that ties the vertical mounting portion to the foot bed. The foot plate also includes a heel cup at a posterior end for engaging the heel of a user. The foot plate also includes a rocker portion underneath the toes of a user, on an anterior end of the foot plate. The rocker portion enables the toes to flex in the dorsal direction during walking without the foot becoming disengaged from the foot plate. |
| FILED | Thursday, July 01, 2021 |
| APPL NO | 17/365768 |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 3/00 (20130101) Original (OR) Class A61H 2201/1215 (20130101) A61H 2201/1642 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220000722 | STEWART et al. |
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| FUNDED BY |
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| APPLICANT(S) | MESOSIL INC. (Toronto, Canada) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Cameron Alexander STEWART (Springwater, Canada); Benjamin David HATTON (Toronto, Canada); Yoav FINER (Toronto, Canada) |
| ABSTRACT | A biocompatible composite material for controlled release is disclosed, comprising a biocompatible metal oxide structure with a loaded network of pores. The pore network of the biocompatible composite material is filled with a uniformly distributed biologically active micellizing amphiphilic molecule, the size of these pores ranging from about 0.5 to about 100 nanometers. The material is characterized in that when exposed to phosphate-buffered saline (PBS), the controlled release of the active amphiphilic molecule is predominantly diffusion-driven over time. |
| FILED | Tuesday, August 31, 2021 |
| APPL NO | 17/463002 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/08 (20130101) A01N 43/40 (20130101) A01N 47/44 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 6/20 (20200101) A61K 6/35 (20200101) A61K 6/40 (20200101) A61K 6/54 (20200101) A61K 6/71 (20200101) A61K 6/74 (20200101) A61K 6/76 (20200101) A61K 6/80 (20200101) A61K 6/84 (20200101) Original (OR) Class A61K 6/86 (20200101) A61K 6/802 (20200101) A61K 6/849 (20200101) A61K 6/853 (20200101) A61K 6/864 (20200101) A61K 6/871 (20200101) A61K 9/0024 (20130101) A61K 9/0063 (20130101) A61K 9/143 (20130101) A61K 9/5115 (20130101) A61K 31/20 (20130101) A61K 31/155 (20130101) A61K 31/444 (20130101) A61K 31/785 (20130101) A61K 31/4425 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/10 (20130101) A61L 27/12 (20130101) A61L 27/025 (20130101) A61L 27/32 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/105 (20130101) A61L 27/306 (20130101) A61L 27/425 (20130101) A61L 27/427 (20130101) A61L 27/446 (20130101) A61L 2300/206 (20130101) A61L 2300/208 (20130101) A61L 2300/404 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/02 (20180101) A61P 31/02 (20180101) A61P 31/04 (20180101) Acyclic or Carbocyclic Compounds C07C 279/14 (20130101) C07C 279/26 (20130101) Heterocyclic Compounds C07D 213/20 (20130101) C07D 213/74 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/22 (20130101) C08K 3/32 (20130101) C08K 2003/325 (20130101) C08K 2003/2227 (20130101) C08K 2003/2237 (20130101) C08K 2003/2296 (20130101) Compositions of Macromolecular Compounds C08L 33/12 (20130101) C08L 2203/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220000765 | STEINBACH-RANKINS et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (Louisville, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | JILL M. STEINBACH-RANKINS (LOUISVILLE, Kentucky); KENNETH PALMER (ANCHORAGE, Kentucky) |
| ABSTRACT | Described herein are antimicrobial (e.g., antibacterial, antiviral) compositions and methods of using such compositions. |
| FILED | Thursday, May 14, 2020 |
| APPL NO | 17/291495 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) Original (OR) Class A61K 9/0036 (20130101) A61K 9/70 (20130101) A61K 9/5153 (20130101) A61K 47/36 (20130101) A61K 47/6811 (20170801) A61K 47/6933 (20170801) A61K 2035/115 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220000768 | Freeman et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (, None) |
| INVENTOR(S) | William Freeman (Del Mar, California); Michael J. Sailor (La Jolla, California); Lingyun Cheng (San Diego, California); Frederique Cunin (Montpellier, France); Emily Anglin (San Diego, California); Yang Yang Li (Hong Kong, China Hong Kong) |
| ABSTRACT | A minimally invasive controlled drug delivery system for delivering a particular drug or drugs to a particular location of the eye, the system including a porous film template having pores configured and dimensioned to at least partially receive at least one drug therein, and wherein the template is dimensioned to be delivered into or onto the eye. |
| FILED | Monday, November 06, 2017 |
| APPL NO | 15/804856 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/0017 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) Original (OR) Class A61K 9/0051 (20130101) A61K 47/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220000790 | Dayton et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); The Arizona Board of Regents on behalf of the University of Arizona (Tucson, Arizona); The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul A. Dayton (Carrboro, North Carolina); Paul S. Sheeran (Durham, North Carolina); Terry O. Matsunaga (Tucson, Arizona); Mark A. Borden (Boulder, Colorado) |
| ABSTRACT | Acoustically activatable particles having low vaporization energy and methods for making and using same are disclosed. A particle of material includes a first substance that includes at least one component that is a gas 25° C. and atmospheric pressure. A second substance, different from the first substance, encapsulates the first substance to create a droplet or emulsion that is stable at room temperature and atmospheric pressure. At least some of the first substance exists in a gaseous phase at the time of encapsulation of the first substance within the second substance to form a bubble. After formation of the bubble, the bubble is condensed into a liquid phase, which causes the bubble to transform into the droplet or emulsion having a core consisting of a liquid. The droplet or emulsion is an activatable phase change agent that remains a droplet having a core consisting of a liquid at 25° C. and atmospheric pressure. The first substance has a boiling point below 25° C. at atmospheric pressure. |
| FILED | Monday, September 20, 2021 |
| APPL NO | 17/479395 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/51 (20130101) Original (OR) Class A61K 9/5123 (20130101) A61K 9/5192 (20130101) A61K 41/0028 (20130101) A61K 47/06 (20130101) A61K 48/00 (20130101) A61K 49/0002 (20130101) A61K 49/221 (20130101) A61K 49/223 (20130101) A61K 49/226 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220000799 | DONG et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| ASSIGNEE(S) | THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| INVENTOR(S) | Jiajia DONG (Shanghai city, China PRC); K. Barry SHARPLESS (La Jolla, California); Jeffery W. KELLY (La Jolla, California); Aleksandra BARANCZAK (Gurnee, Illinois); Wentao CHEN (Walnut Creek, California) |
| ABSTRACT | This application describes modified amino acids and polypeptides comprising a SO2F or CH2CH2SO2F group bound to the side chain of an amono acid or amino acid residue of a polypeptide in place of a hydrogen of a hydroxyl or amino substituent thereof. Methods of covalently binding the polypeptides to receptot sites of receptor proteins are also described herein. |
| FILED | Friday, September 10, 2021 |
| APPL NO | 17/471936 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/05 (20130101) Original (OR) Class A61K 31/14 (20130101) A61K 31/40 (20130101) A61K 31/47 (20130101) A61K 31/53 (20130101) A61K 31/56 (20130101) A61K 31/65 (20130101) A61K 31/70 (20130101) A61K 31/136 (20130101) A61K 31/197 (20130101) A61K 31/198 (20130101) A61K 31/397 (20130101) A61K 31/407 (20130101) A61K 31/439 (20130101) A61K 31/473 (20130101) A61K 31/485 (20130101) A61K 31/505 (20130101) A61K 31/515 (20130101) A61K 31/655 (20130101) A61K 31/4045 (20130101) A61K 31/4168 (20130101) A61K 31/4245 (20130101) A61K 31/4353 (20130101) A61K 31/4709 (20130101) A61K 31/4745 (20130101) A61K 31/5513 (20130101) A61K 31/7048 (20130101) A61K 38/31 (20130101) A61K 47/54 (20170801) A61K 51/0497 (20130101) Acyclic or Carbocyclic Compounds C07C 305/26 (20130101) C07C 2601/14 (20170501) C07C 2603/18 (20170501) Heterocyclic Compounds C07D 277/82 (20130101) C07D 279/08 (20130101) C07D 295/26 (20130101) C07D 295/088 (20130101) C07D 295/185 (20130101) C07D 501/18 (20130101) Peptides C07K 1/02 (20130101) C07K 1/1136 (20130101) C07K 2/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220000837 | Zucker et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| INVENTOR(S) | Irving H. Zucker (Omaha, Nebraska); Hanjun Wang (Omaha, Nebraska) |
| ABSTRACT | The present application provides methods for treating cardiovascular conditions. The methods can include administering a Transient Receptor Potential Vanilloid 1 (TRPV1) receptor agonist to an epidural space. The methods can be used to treat a variety of conditions such as hypertension, prehypertension, mild hypertension, severe hypertension, refractory hypertension, congestive heart failure and myocardial scarring. |
| FILED | Wednesday, July 14, 2021 |
| APPL NO | 17/375796 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0085 (20130101) A61K 31/357 (20130101) Original (OR) Class A61K 31/4468 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220000842 | Huang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Georgetown University (Washington, District of Columbia) |
| ASSIGNEE(S) | Georgetown University (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey Huang (Bethesda, Maryland); Maryna Baydyuk (Speingfield, Virginia) |
| ABSTRACT | The present application is directed to methods and compositions for treating a condition marked by enhanced inflammation in the central nervous system (CNS). The methods comprise administering to a subject in need of treatment of enhanced inflammation in the CNS an inhibitor of an amino acid transporter in inflammatory cells present in the CNS. The compositions of the present invention relate to compositions comprising an inhibitor of an amino acid transporter in inflammatory cells, or a pharmaceutically acceptable salt thereof, wherein the composition is formulated for direct administration into the CNS of a mammal. |
| FILED | Wednesday, October 02, 2019 |
| APPL NO | 17/281659 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/423 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220000862 | HERGENROTHER et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Paul J. HERGENROTHER (Champaign, Illinois); Matthew Wesley BOUDREAU (Urbana, Illinois) |
| ABSTRACT | Synergistic drug combinations with the small molecule PAC-1 against uveal or cutaneous melanoma. There are no current targeted drug treatments for the mutations associated with uveal melanoma. Despite primary radiation or surgical therapy, up to 50% of patients eventually develop metastatic disease, for which there is no standard therapy nor treatment shown to improve overall survival. Drug combinations with PAC-1 allow the use of lower dosages of this compound that result in cancer cell death in uveal melanoma. Drug combinations of PAC-1 with the kinase inhibitor entrectinib have shown a synergistic effect against uveal melanoma cell lines. Specifically, PAC-1 and entrectinib are synergistic against wild-type and mutant uveal melanoma cell lines (e.g., GNAQ and GNA11). |
| FILED | Thursday, October 03, 2019 |
| APPL NO | 17/281453 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/496 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220000867 | Sotomayor et al. |
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| FUNDED BY |
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| APPLICANT(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eduardo M. Sotomayor (Tampa, Florida); Alejandro V. Villagra (Tampa, Florida) |
| ABSTRACT | Disclosed are methods whereby an effective amount of a HDAC6 inhibitor is used to activate a subjects T-cell response to tumor or tumor vaccine. Methods of using HDAC6 inhibitors to increase a subjects anti-tumor immune response, alone or in conjunction with other tumor treatments, are also disclosed. |
| FILED | Tuesday, February 16, 2021 |
| APPL NO | 17/176243 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/17 (20130101) A61K 31/69 (20130101) A61K 31/416 (20130101) A61K 31/422 (20130101) A61K 31/437 (20130101) A61K 31/454 (20130101) A61K 31/505 (20130101) Original (OR) Class A61K 39/0011 (20130101) A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 2039/57 (20130101) A61K 2039/545 (20130101) A61K 2039/585 (20130101) A61K 2039/5158 (20130101) A61K 2039/55511 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 5/0638 (20130101) C12N 2501/065 (20130101) C12N 2501/2302 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220000873 | Watson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Buck Institute for Research on Aging (Novato, California) |
| ASSIGNEE(S) | Buck Institute for Research on Aging (Novato, California) |
| INVENTOR(S) | Mark A. Watson (Northfield, Birmingham, United Kingdom); Martin D. Brand (San Rafael, California); Pankaj Kapahi (Kensington, California) |
| ABSTRACT | In various embodiments methods for the treatment or prophylaxis of an age-related and/or pathology-associated increase in intestinal barrier permeability are provided. In certain embodiments the methods comprise administering to a mammal in need thereof an effective amount of one or more agent(s) that inhibit superoxide or hydrogen peroxide production from the outer ubiquinone-binding site of complex III of the mitochondrial electron transport chain (site IIIQo). |
| FILED | Monday, December 09, 2019 |
| APPL NO | 17/311975 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/343 (20130101) A61K 31/445 (20130101) A61K 31/495 (20130101) A61K 31/517 (20130101) A61K 31/519 (20130101) Original (OR) Class A61K 31/4365 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) A61P 3/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220000883 | Ganesh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thota Ganesh (Alpharetta, Georgia); Jianxiong Jiang (Memphis, Tennessee); Raymond Dingledine (Norcross, Georgia) |
| ABSTRACT | The disclosure relates to Prostaglandin receptor EP2 antagonists, derivatives, compositions, and methods related thereto. In certain embodiments, the disclosure relates to methods of treating or preventing conditions and diseases in which EP2 receptor activation has a physiological role, such as but not limited to, brain injury, inflammatory diseases, neuroinflamation after a seizure, pain, endometriosis, cancer, rheumatoid arthritis, skin inflammation, vascular inflammation, colitis, and neurological disorders by administering a pharmaceutical composition comprising a compound disclosed herein to a subject in need thereof. |
| FILED | Thursday, July 15, 2021 |
| APPL NO | 17/376944 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) A61K 31/454 (20130101) A61K 31/496 (20130101) A61K 31/506 (20130101) A61K 31/517 (20130101) A61K 31/551 (20130101) Original (OR) Class A61K 31/4184 (20130101) A61K 31/4192 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220000884 | ARONOFF |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David ARONOFF (Nashville, Tennessee) |
| ABSTRACT | The present invention relates to compositions and methods for the treatment or prevention of the recurrence of C. difficile infections using misoprostol. |
| FILED | Tuesday, September 14, 2021 |
| APPL NO | 17/474258 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/20 (20130101) A61K 9/209 (20130101) A61K 31/5575 (20130101) Original (OR) Class A61K 31/7042 (20130101) A61K 35/741 (20130101) A61K 35/745 (20130101) A61K 35/747 (20130101) A61K 38/14 (20130101) A61K 39/395 (20130101) A61K 45/06 (20130101) A61K 2035/115 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220000899 | Korinek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ASTROCYTE PHARMACEUTICALS, INC. (Cambridge, Massachusetts); THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | William S. Korinek (Mystic, Connecticut); James D. Lechleiter (San Antonio, Texas); Theodore E. Liston (Stonington, Connecticut) |
| ABSTRACT | The present invention relates to compounds and methods of use thereof for treatment of certain disorders and conditions, for example brain injuries such as stroke or traumatic brain injuries. |
| FILED | Friday, February 19, 2021 |
| APPL NO | 17/180469 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/52 (20130101) A61K 31/7076 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220000920 | Mamonkin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Baylor College of Medicine (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Maksim Mamonkin (Houston, Texas); Malcolm K. Brenner (Houston, Texas); Feiyan Mo (Houston, Texas) |
| ABSTRACT | Embodiments of the disclosure concern engineered auto/allo-immune defense receptor (ADR)-expressing T cells that selectively target activated T cells, including pathogenic T cells, to incapacitate them. The chimeric receptors comprise moieties for targeting 4-1BB, OX40, and CD40L, for example, whose expression is indicative of activated T cells. In particular embodiments, there are methods of preventing or treating conditions associated with activated T cells using adoptive T-cell transfer of cells encoding the ADRs. |
| FILED | Friday, February 26, 2021 |
| APPL NO | 17/187399 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/06 (20180101) Peptides C07K 14/70575 (20130101) C07K 14/70578 (20130101) C07K 2319/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220000974 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Oncolmmune, Inc. (Rockville, Maryland); Children's Research Institute, Children's National Medical Center (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yang Liu (Washington, District of Columbia); Pan Zheng (Washington, District of Columbia); Xu Wang (Washington, District of Columbia); Martin Devenport (Gaithersburg, Maryland) |
| ABSTRACT | Provided herein are methods and compositions for lowering low-density lipoprotein cholesterol or glucose levels, and for treating subjects with prediabetes or diabetes by targeting CD24-Siglec interactions. |
| FILED | Wednesday, February 05, 2020 |
| APPL NO | 17/428784 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/177 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/06 (20180101) A61P 3/10 (20180101) Peptides C07K 14/70596 (20130101) C07K 2319/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220000976 | CHATILA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Talal A. CHATILA (Boston, Massachusetts); Azza ABDEL-GADIR (Boston, Massachusetts); Emmanuel Stephen VICTOR (Udayagiri, India); Rima RACHID (Belmont, Massachusetts) |
| ABSTRACT | Described herein are methods and compositions for treating or preventing a food allergy. Aspects of the invention relates to administering to a subject an agent that induces a regulatory T cell, or population thereof, that expresses ROR yt. Another aspect of the invention relates to administering a fecal matter transplant to a subject having reduced ROR yt-expressing regulatory T cells to treat or prevent a food allergy. |
| FILED | Friday, November 08, 2019 |
| APPL NO | 17/292319 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/404 (20130101) A61K 35/76 (20130101) A61K 38/1783 (20130101) Original (OR) Class A61K 48/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/08 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220000994 | Shea et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lonnie D. Shea (Evanston, Illinois); Stephen D. Miller (Evanston, Illinois); Jonathan Woon Teck Yap (Evanston, Illinois); Daniel R. Getts (Northbrook, Illinois); Derrick McCarthy (Evanston, Illinois) |
| ABSTRACT | The present invention provides compositions comprising peptide-coupled biodegradable poly(lactide-co-glycolide) (PLG) particles. In particular, PLG particles are surface-functionalized to allow for coupling of peptide molecules to the surface of the particles (e.g., for use in eliciting induction of immunological tolerance). |
| FILED | Wednesday, June 30, 2021 |
| APPL NO | 17/364351 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/19 (20130101) A61K 9/1647 (20130101) A61K 9/5153 (20130101) A61K 39/00 (20130101) A61K 39/0008 (20130101) Original (OR) Class A61K 47/58 (20170801) A61K 47/6911 (20170801) A61K 47/6935 (20170801) A61K 47/6937 (20170801) A61K 2039/622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001004 | Demehri |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shadmehr Demehri (Charlestown, Massachusetts) |
| ABSTRACT | Immune-based approaches to treat and prevent skin cancer by boosting T cell immunity against commensal HPVs present on skin. Thus, provided herein are compositions comprising: (i) a plurality of antigenic peptides each comprising a sequence of 9-30 amino acids derived from proteins from commensal human papilloma viruses, (ii) a plurality of live or live attenuated commensal human papilloma viruses, (iii) a plurality of antigenic proteins from commensal human papilloma viruses, preferably in virus-like particles, and/or (iv) a plurality of nucleic acids encoding (a) a plurality of antigenic peptides, each comprising a sequence of 9-30 amino acids derived from proteins from commensal human papilloma viruses or (b) a plurality of antigenic proteins from commensal human papilloma viruses; and optionally a T cell adjuvant that increases T cell response to the antigenic peptides. |
| FILED | Tuesday, November 26, 2019 |
| APPL NO | 17/296829 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/5258 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/20034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001006 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota); New York Blood Center, Inc. (New York, New York) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota); New York Blood Center, Inc. (New York, New York) |
| INVENTOR(S) | Frank Jonathan Lee (Minneapolis, Minnesota); Qibin Geng (Minneapolis, Minnesota); Jian Shang (Minneapolis, Minnesota); Marc Jenkins (Minneapolis, Minnesota); Sung-Wook Hong (Minneapolis, Minnesota); Lanying Du (New York, New York); Wanbo Tai (New York, New York); Yushun Wan (Minneapolis, Minnesota) |
| ABSTRACT | The present disclosure provides virus like nanoparticles (VLPs), which are capable of displaying multiple copies of a SARS-CoV-2 antigen, for eliciting protective immunity against a SARS-CoV-2 infection, as well as polypeptides, compositions and methods thereof. |
| FILED | Tuesday, June 29, 2021 |
| APPL NO | 17/361486 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/215 (20130101) Original (OR) Class Peptides C07K 16/10 (20130101) C07K 2317/52 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/20023 (20130101) C12N 2770/20034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001011 | Basilion |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James Basilion (Shaker Heights, Ohio) |
| ABSTRACT | A photodynamic therapy composition, the composition includes a plurality of targeted phthalocyanine gold nanoparticle conjugates, wherein each targeted phthalocyanine gold nanoparticle conjugate includes a plurality of phthalocyanine compounds covalently coupled to a surface of the gold nanoparticle via bio-cleavable linker and a plurality of cancer or tissue targeting agents coupled to the gold nanoparticle. |
| FILED | Tuesday, July 06, 2021 |
| APPL NO | 17/368574 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 41/0057 (20130101) Original (OR) Class A61K 47/60 (20170801) A61K 47/65 (20170801) A61K 47/6929 (20170801) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001018 | Ji et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Peng Ji (Wilmelte, Illinois); Gary E. Schillz (Naperville, Illinois); Rama K. Mishra (Chicago, Illinois); Atul D. Jain (Chicago, Illinois) |
| ABSTRACT | Disclosed herein are compounds, compositions, and methods for treating cell proliferative diseases and disorders based on present inventors discovery that Pleckstrin-2 (Plek2) can be targeted to treat cell proliferative diseases and disorders. The compositions and methods disclosed herein include or utilize the disclosed compounds as therapeutic agents which inhibit the biological activity or expression of Pleckstrin-2 (Plek2) and collectively may be referred to as “Plek2 inhibitors.” Disclosed are small molecule inhibitors of Plek2 biological activity. The compositions and method may be utilized for treating cell proliferative diseases and disorders that are characterized by elevated levels of Plek2 expression and/or by activation of the phosphatidylinositide 3-kinase (PI3K)/Akt pathway. Cell proliferative diseases and disorders that may be treated using the disclosed compositions and methods may include, but not limited to, myeloproliferative neoplasms (MPNs) such as Philadelphia (Ph)-negative MPNs, and cancers such as acute myeloid leukemia (AML) and cancers characterized by solid tumors. |
| FILED | Friday, November 01, 2019 |
| APPL NO | 17/309179 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/54 (20170801) A61K 47/55 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 403/06 (20130101) C07D 409/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001019 | Soo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | B. Chia Soo (Los Angeles, California); Kang Ting (Los Angeles, California); Benjamin M. Wu (San Marino, California) |
| ABSTRACT | The present invention discloses a random conjugate molecule (CMN), comprising a formula of CG-X-N and methods of making and using the same. The present invention also discloses a composition comprising the CMN and methods of making and using the composition. |
| FILED | Friday, April 03, 2020 |
| APPL NO | 16/839717 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/19 (20130101) A61K 47/60 (20170801) A61K 47/64 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001035 | Ran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chongzhao Ran (Winchester, Massachusetts); Anna Moore (Stoneham, Massachusetts); Jian Yang (Boston, Massachusetts) |
| ABSTRACT | Provided herein are curcumin analogues that are able to interact with amyloid beta (Aβ) and to attenuate the copper-induced crosslinking of Aβ. Also provided herein are methods of using the compounds as imaging agents of amyloid beta and for the treatment of diseases associated with amyloid beta. Methods of preparing unlabeled and radiolabeled compounds useful for interacting with amyloid beta and pharmaceutical compositions are also provided. |
| FILED | Wednesday, September 22, 2021 |
| APPL NO | 17/448463 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/04 (20130101) A61K 51/0453 (20130101) Original (OR) Class A61K 51/0455 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) General Methods of Organic Chemistry; Apparatus Therefor C07B 59/002 (20130101) Acyclic or Carbocyclic Compounds C07C 49/248 (20130101) C07C 49/252 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001036 | Ran et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chongzhao Ran (Winchester, Massachusetts); Anna Moore (Stoneham, Massachusetts); Jian Yang (Boston, Massachusetts) |
| ABSTRACT | Provided herein are curcumin analogues that are able to interact with amyloid beta (Aβ) and to attenuate the copper-induced crosslinking of Aβ. Also provided herein are methods of using the compounds as imaging agents of amyloid beta and for the treatment of diseases associated with amyloid beta. Methods of preparing unlabeled and radiolabeled compounds useful for interacting with amyloid beta and pharmaceutical compositions are also provided. |
| FILED | Tuesday, September 21, 2021 |
| APPL NO | 17/480924 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/04 (20130101) A61K 51/0453 (20130101) Original (OR) Class A61K 51/0455 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) General Methods of Organic Chemistry; Apparatus Therefor C07B 59/002 (20130101) Acyclic or Carbocyclic Compounds C07C 49/248 (20130101) C07C 49/252 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001039 | Thorek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Daniel Thorek (St. Louis, Missouri); Hanwen Zhang (St. Louis, Missouri); Diane Abou (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Daniel Thorek (St. Louis, Missouri); Hanwen Zhang (St. Louis, Missouri); Diane Abou (St. Louis, Missouri) |
| ABSTRACT | Among the various aspects of the present disclosure is the provision of compositions of imaging agents and methods for use in imaging ACE2 expression profiles. The ACE2 expression profiles may be used for detecting, monitoring, and evaluating ACE2 associated diseases, disorders, and conditions. |
| FILED | Friday, June 25, 2021 |
| APPL NO | 17/359490 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/08 (20130101) Original (OR) Class A61K 51/0482 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001189 | EFIMOV et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | The Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Igor R. EFIMOV (Arlington, Virginia); Wenwen LI (St. Louis, Missouri); Ajit JANARDHAN (St. Louis, Missouri) |
| ABSTRACT | Methods and apparatus for a three-stage atrial cardioversion therapy that treats atrial arrhythmias within pain tolerance thresholds of a patient An implantable therapy generator adapted to generate and selectively deliver a three-stage atrial cardioversion therapy and at least two leads, each having at least one electrode adapted to he positioned proximate the atrium of the patient. The device is programmed for delivering a three-stage atrial cardioversion therapy via both a far-field configuration and a near-field configuration of the electrodes upon detection of an atrial arrhythmia. The three-stage atrial cardioversion therapy includes a first stage for unpinning of one or more singularities associated with an atrial arrhythmia, a second stage for anti-repinning of the one or more singularities, both of which are delivered via the far-field configuration of the electrodes, and a third stage for extinguishing of tire one or more singularities delivered via the near-field configuration of the electrodes. |
| FILED | Monday, July 19, 2021 |
| APPL NO | 17/305972 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/395 (20130101) A61N 1/3624 (20130101) A61N 1/3906 (20130101) A61N 1/3956 (20130101) Original (OR) Class A61N 1/3987 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001193 | ZHU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Timothy C. ZHU (Glen Mills, Pennsylvania); Arjun G. YODH (Merion, Pennsylvania) |
| ABSTRACT | Methods and systems are described for implementing a photodynamic therapy. An example method may comprise determining, during photodynamic therapy and using a plurality of optical probes spatially distributed within a patient, data indicative of one or more of a photodynamic therapy dosage, a fluence rate of a photodynamic therapy treatment light, or a reactive oxygen species concentration associated with corresponding locations of the plurality of optical probes. The example method may comprise changing, based on the data, one or more treatment parameters associated with providing a photodynamic therapy. |
| FILED | Wednesday, November 06, 2019 |
| APPL NO | 17/291703 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0261 (20130101) A61B 5/1459 (20130101) A61B 5/4836 (20130101) A61B 5/6852 (20130101) A61B 2562/228 (20130101) A61B 2562/0233 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) Original (OR) Class A61N 5/0603 (20130101) A61N 2005/063 (20130101) A61N 2005/0628 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001197 | Huettemann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wayne state University (Detroit, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Maik Huettemann (Grosse Pointe Park, Michigan); Mauri ce-Andre Recanati (New York, New York); Thomas H. Sanderson (Plymouth, Michigan) |
| ABSTRACT | A method and apparatus for minimizing tissue adhesion in a tissue of a subject includes applying light, to the tissue, that reduces at least one adhesion marker in the tissue, the light having wavelengths in at least one of a first wavelength range of 730-770 nm and a second wavelength range of 930-970 nm, wherein the at least one adhesion marker includes at least one of a transforming growth factor beta 1 (TGF-β1), a vascular endothelial growth factor, (VEGF), and a collagen alpha-1(I) chain (COL|α|), and wherein the light is free of wavelengths that increase the at least one adhesion marker. |
| FILED | Thursday, October 31, 2019 |
| APPL NO | 17/290577 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 5/0603 (20130101) A61N 5/0616 (20130101) Original (OR) Class A61N 2005/063 (20130101) A61N 2005/0652 (20130101) A61N 2005/0659 (20130101) A61N 2005/0663 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001357 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Sumin Lee (Berkeley, California); Adam Uliana (Berkeley, California); Jeffrey R. Long (Berkeley, California); Christopher J. Chang (Berkeley, California) |
| ABSTRACT | Ether-thioether functionalized porous aromatic framework (PAF) polymers provide high selectivity for iron(II) and iron(III) adsorption in aqueous samples. |
| FILED | Friday, September 17, 2021 |
| APPL NO | 17/478874 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/265 (20130101) Original (OR) Class B01J 20/3085 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/285 (20130101) C02F 2101/203 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 31/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001378 | ZENHAUSERN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona); The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Frederic ZENHAUSERN (Phoenix, Arizona); Brett DUANE (Phoenix, Arizona); Jian GU (Phoenix, Arizona); Alan NORDQUIST (Phoenix, Arizona); David BRENNER (New York, New York); Mikhail REPIN (New York, New York) |
| ABSTRACT | Provided herein are methods and related devices for preprocessing a biological sample during transit. The method may comprise the steps of: storing a biological sample in a storage container having walls that defines a storage volume; transporting the storage container with the stored biological sample to a sample processing facility; controlling one or more storage container parameters during the transporting step to initiate preprocessing of the biological sample; wherein the controlling step improves a processing parameter at the sample processing facility. |
| FILED | Thursday, December 05, 2019 |
| APPL NO | 17/293707 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50 (20130101) Original (OR) Class B01L 2200/185 (20130101) B01L 2300/18 (20130101) B01L 2300/021 (20130101) B01L 2300/023 (20130101) B01L 2300/0663 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002274 | Witt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Trustees of the Southern Illinois University (Edwardsville, Illinois) |
| ASSIGNEE(S) | Board of Trustees of the Southern Illinois University (Edwardsville, Illinois) |
| INVENTOR(S) | Kenneth A. Witt (Edwardsville, Illinois); Albert M. Crider (Maryville, Illinois); William Neumann (St. Louis, Missouri); Audrey Hospital (Robbinsville, New Jersey); Karin Sandoval (Edwardsville, Illinois); Maria Kontoyianni (Glen Carbon, Illinois) |
| ABSTRACT | The present disclosure describes novel compounds that are somatostatin receptor type 4 agonists. |
| FILED | Friday, September 03, 2021 |
| APPL NO | 17/466480 |
| CURRENT CPC | Heterocyclic Compounds C07D 401/14 (20130101) C07D 403/06 (20130101) C07D 403/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002296 | AUGERI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| INVENTOR(S) | David J. AUGERI (New Brunswick, New Jersey); Hatem SABAAWY (New Brunswick, New Jersey); John A. GILLERAN (New Brunswick, New Jersey) |
| ABSTRACT | The invention provides compounds of formula (16) and (17); and salts thereof, as well as compositions comprising such compounds and salts, complexes comprising such compounds and salts, and methods for treating cancer, inhibiting BMI1 expression, or treating Huntington's disease using such compounds, salts, and complexes. The compounds, salts, and complexes have potency, permeability, and oral bioavailability that make them particularly useful, for example, for the treatment of glioblastoma. |
| FILED | Tuesday, November 26, 2019 |
| APPL NO | 17/297397 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/05 (20130101) Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002300 | JANDA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kim D. JANDA (La Jolla, California); Nicholas T. JACOB (San Diego, California); Jonathan W. LOCKNER (San Diego, California) |
| ABSTRACT | There are disclosed imidazolinopyrimidinone compounds that have activity to induce TRAIL gene expression in macrophages. There is further disclosed a method for treating various cancers comprising administering effective amounts of an imidazolinopyrimidinone having the structure of Formula I herein. |
| FILED | Monday, July 12, 2021 |
| APPL NO | 17/372894 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) Heterocyclic Compounds C07D 471/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002322 | BURNS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VenatoRx Pharmaceuticals, Inc. (Malvern, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher J. BURNS (Malvern, Pennsylvania); Daniel C. PEVEAR (Downingtown, Pennsylvania); Luigi XERRI (Wayne, Pennsylvania); Timothy HENKEL (Berwyn, Pennsylvania); Daniel MCGARRY (Malvern, Pennsylvania); Lawrence ROSEN (Malvern, Pennsylvania); Gerald BRENNER (Plymouth, Pennsylvania); Jean-Baptiste ARLIN (Amsterdam, Netherlands); Ana FERNANDEZ CASARES (Amsterdam, Netherlands) |
| ABSTRACT | Described herein are crystalline forms of (R)-3-(2-(trans-4-(2-aminoethylamino)cyclohexyl)acetamido)-2-hydroxy-3,4-dihydro-2H-benzo[e][1,2]oxaborinine-8-carboxylic acid. In some embodiments, the crystalline forms are formulated for treating a subject in need thereof with a bacterial infection. |
| FILED | Monday, June 21, 2021 |
| APPL NO | 17/353377 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0095 (20130101) A61K 31/546 (20130101) A61K 47/02 (20130101) A61K 47/12 (20130101) A61K 47/26 (20130101) A61K 47/183 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/027 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002328 | Jeon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Junha Jeon (Southlake, Texas); Hiep Hoang Nguyen (Arlington, Texas) |
| ABSTRACT | The present disclosure provides compounds that may be used as ligands in metal-catalyzed reactions, in particular 3,3′-bisilyl biaryl phosphoramidite compounds and processes for preparing the same. |
| FILED | Friday, July 02, 2021 |
| APPL NO | 17/366374 |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/081 (20130101) C07F 7/0812 (20130101) C07F 7/0829 (20130101) C07F 9/65744 (20130101) C07F 9/65842 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002335 | BOUGHER, III et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Chimerix, Inc. (Durham, North Carolina); The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John Henry BOUGHER, III (Durham, North Carolina); Ramamurty V S CHANGALVALA (Durham, North Carolina); Aaron Leigh DOWNEY (Durham, North Carolina); John C. DRACH (Ann Arbor, Michigan); Ernest Randall LANIER, JR. (Durham, North Carolina); Andrew Louis MCIVER (Durham, North Carolina); Bradley David ROBERTSON (Durham, North Carolina); Dean Wallace SELLESETH (Durham, North Carolina); Phiroze Behram SETHNA (Durham, North Carolina); Leroy TOWNSEND (Ann Arbor, Michigan); Roy W. WARE (Durham, North Carolina) |
| ABSTRACT | The present disclosure provides pyrrolopyrimidine nucleoside analogs of the Formula I, Formula IA, Formula IB, or Formula II and phospholipid conjugates and pharmaceutical compositions thereof wherein Rc and A are defined herein. Also presented are methods of treating and/or preventing viral infection and/or viral infection-associated disease or disorder with one or more compounds of Formula I, Formula IA, Formula IB, or Formula II. |
| FILED | Wednesday, January 27, 2021 |
| APPL NO | 17/159451 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7052 (20130101) Heterocyclic Compounds C07D 239/70 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/14 (20130101) Original (OR) Class C07H 19/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002342 | MACMILLAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David MACMILLAN (Princeton, New Jersey); Daniel Novoa (New York, New York); Stefan McCarver (Princeton, New Jersey) |
| ABSTRACT | Synthetic methods are described herein operable to efficiently produce a wide variety of molecular species through conjugate additions via decarboxylative mechanisms. For example, methods of functionalization of peptide residues are described, including selective functionalization of peptide C-terminal residues. In one aspect, a method of peptide functionalization comprises providing a reaction mixture including a Michael acceptor and a peptide and coupling the Michael acceptor with the peptide via a mechanism including decarboxylation of a peptide reside. |
| FILED | Wednesday, September 08, 2021 |
| APPL NO | 17/469102 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/181 (20130101) B01J 31/1815 (20130101) B01J 35/004 (20130101) B01J 2231/324 (20130101) B01J 2231/348 (20130101) B01J 2531/827 (20130101) B01J 2540/12 (20130101) B01J 2540/22 (20130101) B01J 2540/225 (20130101) Peptides C07K 1/107 (20130101) C07K 1/113 (20130101) Original (OR) Class C07K 5/0205 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/29 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002346 | LOKEY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | R. Scott LOKEY (Santa Cruz, California); Akihiro FURUKAWA (Tokyo, Japan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | R. Scott LOKEY (Santa Cruz, California); Akihiro FURUKAWA (Tokyo, Japan) |
| ABSTRACT | Molecular scaffolds, including cyclic peptides, that have high (large) cell permeability. |
| FILED | Friday, July 02, 2021 |
| APPL NO | 17/366822 |
| CURRENT CPC | Peptides C07K 7/54 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002351 | Kwong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Servic (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Servic (Bethesda, Mississippi) |
| INVENTOR(S) | Peter D. Kwong (Washington, District of Columbia); Barney S. Graham (Rockville, Maryland); Jason S. McLellan (Austin, Texas); Jeffrey Boyington (Clarksburg, Maryland); Lei Chen (Rockville, Maryland); Man Chen (Bethesda, Maryland); Gwo-Yu Chuang (Rockville, Maryland); Ivelin Stefanov Georgiev (Nashville, Tennessee); Jason Gorman (Washington, District of Columbia); Michael Gordon Joyce (Washington, District of Columbia); Masaru Kanekiyo (Chevy Chase, Maryland); Gilad Ofek (Gaithersburg, Maryland); Marie Pancera (Seattle, Washington); Mallika Sastry (Rockville, Maryland); Cinque Soto (Rockville, Maryland); Sanjay Srivatsan (Liburn, Georgia); Guillaume Stewart-Jones (Cambridge, Massachusetts); Yongping Yang (Potomac, Maryland); Baoshan Zhang (Bethesda, Maryland); Tongqing Zhou (Boyds, Maryland) |
| ABSTRACT | Disclosed are Respiratory Syncytial Virus (RSV) antigens including a recombinant RSV F protein stabilized in a prefusion conformation. Also disclosed are nucleic acids encoding the antigens and methods of producing the antigens. Methods for generating an immune response in a subject are also disclosed. In some embodiments, the method is a method for treating or preventing a RSV infection in a subject by administering a therapeutically effective amount of the antigen to the subject. |
| FILED | Friday, September 17, 2021 |
| APPL NO | 17/478533 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/155 (20130101) A61K 2039/5252 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002354 | Crawford et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jason Crawford (Shelton, Connecticut); Jhe-Hao Li (New Haven, Connecticut); Joonseok Oh (West Haven, Connecticut) |
| ABSTRACT | The present disclosure includes a construct comprising a leupeptin biosynthesis operon, the operon comprising leupA, leupB, leupC, and leupD genes operably linked to a promoter. Also included are cells comprising the construct, and methods for production of leupeptin peptide. |
| FILED | Wednesday, June 30, 2021 |
| APPL NO | 17/363433 |
| CURRENT CPC | Peptides C07K 14/195 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002357 | Strachan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ryan Strachan (Chapel Hill, North Carolina); Reid Olsen (Oxford, United Kingdom); Bryan Leo Roth (Durham, North Carolina); Justin Gregory English (Chapel Hill, North Carolina); Jeffrey Frederick Diberto (Carrboro, North Carolina) |
| ABSTRACT | Disclosed herein is a G protein-coupled receptor (GPCR) assay platform comprised of two complementary systems that equate dynamic intermolecular interactions between a receptor and transducer with more complex stimulus-response cascades in living cells. In the disclosed in vitro ADSoRB method, the forced dissociation of transducers like G protein heterotrimers from receptors alters receptor conformations and ligand interactions to simulate pathway activation in a cell. In the disclosed TRUPATH method, measuring the extent of engineered G protein heterotrimer complex dissociation provides single transducer resolution in a cell. |
| FILED | Tuesday, December 03, 2019 |
| APPL NO | 17/296818 |
| CURRENT CPC | Peptides C07K 14/39 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/52 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/566 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002363 | Matute-Bello et al. |
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| FUNDED BY |
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| APPLICANT(S) | United States Government As Represented By The Department of Veterans Affairs (Washington, District of Columbia); University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gustavo Matute-Bello (Seattle, Washington); Osamu Kajikawa (Seattle, Washington) |
| ABSTRACT | Disclosed herein, are peptides capable of inhibiting sFasL activity, and pharmaceutical compositions containing the peptides and methods treating a pulmonary disease. |
| FILED | Friday, July 02, 2021 |
| APPL NO | 17/366844 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) Peptides C07K 14/4703 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002369 | Hartigan-O'Connor |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Dennis Hartigan-O'Connor (Davis, California) |
| ABSTRACT | Provided herein are systems, compositions, and methods for expressing an antigen and a protein having interleukin-10-like activity in a cell. The systems, compositions, and methods described herein can be used to induce an immune response against an antigen and are useful, for example, in the prevention and treatment of a number of infectious diseases and cancers. |
| FILED | Thursday, June 17, 2021 |
| APPL NO | 17/350898 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/04 (20130101) A61K 39/21 (20130101) A61K 39/39 (20130101) A61K 39/001186 (20180801) A61K 2039/55527 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) A61P 35/00 (20180101) Peptides C07K 14/5428 (20130101) Original (OR) Class C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 2740/15022 (20130101) C12N 2740/15034 (20130101) C12N 2740/15071 (20130101) C12N 2740/16034 (20130101) C12N 2750/14143 (20130101) C12N 2750/14171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002373 | WEISS |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael A. WEISS (Indianapolis, Indiana) |
| ABSTRACT | A single-chain insulin analogue containing an engineered C-domain segment of lengths 4-11 conforming to the sequence pattern [Asp/Glu]-Ala-An-Ala-Xaa where An designates a sub-segment of 0-7 Alanine residues and where Xaa designates an amino-acid residue selected from the amino acids Alanine, Arginine, Asparagine, Aspartic Acid, Glutamic Acid, Histine, Lysine and Serine. The analogue may be an analogue of a mammalian insulin, such as human insulin, may optionally include standard or non-standard modifications that (i) augment the stability of insulin, (ii) cause a shift in the isoelectric point to enhance or impair the solubilty of the protein at neutral pH or (iii) reduce cross-binding of the protein to the Type I IGF receptor. A method of treating a patient with diabetes mellitus comprising the administration of a physiologically effective amount of the protein or a physiologically acceptable salt thereof to a patient. |
| FILED | Tuesday, November 19, 2019 |
| APPL NO | 17/294948 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/62 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002379 | Kuhns et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael S. Kuhns (Tucson, Arizona); Deepta Bhattacharya (Tucson, Arizona); Heather Lynn Bronnimann (Tucson, Arizona) |
| ABSTRACT | Surrogate co-receptors for T cells, including T cells expressing chimeric receptors comprising major histocompatibility molecules grafted onto T cell receptor molecules. The surrogate co-receptors feature a portion of CD8, wherein the Ig domains of CD8 are replaced with Ig domains that confer novel specificities (e.g. antibody Fv fragments specific for a target of interest.) The surrogate co-receptors may be used to help enhance CRMpMHC-CD3 signaling as part of a 5-module receptor system. The present invention also describes Lck fusions. |
| FILED | Monday, September 20, 2021 |
| APPL NO | 17/479898 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Peptides C07K 14/705 (20130101) C07K 14/7051 (20130101) C07K 14/70539 (20130101) Original (OR) Class C07K 2319/02 (20130101) C07K 2319/03 (20130101) C07K 2319/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 9/12 (20130101) Enzymes C12Y 207/10002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002382 | Dranoff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Glenn Dranoff (Sudbury, Massachusetts); Matthew Vanneman (Cambridge, Massachusetts); Gordon Freeman (Brookline, Massachusetts) |
| ABSTRACT | Methods for cancer immunotherapy are provided. The methods involve the use of a chimeric molecule (e.g., fusion protein) comprising an NKG2D portion and an Fc portion, which binds one or more NKG2D ligands. The methods disclosed herein are useful for the treatment of cancer that is associated with abnormal expression of one or more NKG2D ligands. |
| FILED | Friday, April 02, 2021 |
| APPL NO | 17/221295 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/177 (20130101) A61K 45/06 (20130101) Peptides C07K 14/7056 (20130101) C07K 14/70596 (20130101) Original (OR) Class C07K 2319/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002383 | Wong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Altor BioScience, LLC. (Culver City, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hing C. Wong (Weston, Florida); Peter Rhode (Miami, Florida); Bai Liu (Cooper City, Florida); Xiaoyun Zhu (Weston, Florida); Kai-Ping Han (Weston, Florida) |
| ABSTRACT | The present invention features compositions and methods featuring ALT-803, a complex of an interleukin-15 (IL-15) superagonist mutant and a dimeric IL-15 receptor α/Fc fusion protein useful for enhancing an immune response against a neoplasia (e.g., multiple myeloma, melanoma, lymphoma) or a viral infection (e.g., human immunodeficiency virus). |
| FILED | Monday, July 26, 2021 |
| APPL NO | 17/385714 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/1793 (20130101) A61K 38/2086 (20130101) A61K 39/3955 (20130101) A61K 45/06 (20130101) Peptides C07K 14/5443 (20130101) C07K 14/7155 (20130101) Original (OR) Class C07K 16/18 (20130101) C07K 16/2887 (20130101) C07K 2317/622 (20130101) C07K 2317/732 (20130101) C07K 2319/21 (20130101) C07K 2319/22 (20130101) C07K 2319/30 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/09 (20130101) C12N 15/62 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002387 | Termini et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MIAMI (Miami, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James M. Termini (Miami, Florida); Ronald Desrosiers (Miami, Florida) |
| ABSTRACT | The disclosure provides an expression vector (e.g., AAV vector) comprising a nucleic acid sequence encoding (1) the heavy and/or light chain of an antibody and (2) one or more shRNA sequences targeting fucosyltransferase-8 (FUT8). |
| FILED | Wednesday, November 06, 2019 |
| APPL NO | 17/291884 |
| CURRENT CPC | Peptides C07K 16/00 (20130101) Original (OR) Class C07K 2317/41 (20130101) C07K 2317/52 (20130101) C07K 2317/732 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1051 (20130101) C12N 15/86 (20130101) C12N 15/1137 (20130101) C12N 2310/531 (20130101) C12N 2750/14143 (20130101) Enzymes C12Y 204/01068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002390 | Mouquet et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Rockefeller University (New York, New York); California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | The Rockefeller University (New York, New York); California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Hugo Mouquet (New York, New York); Michel Nussenzweig (New York, New York); Pamela J. Bjorkman (La Canada Flintridge, California); Louise Scharf (Porter Ranch, California) |
| ABSTRACT | The present invention relates to anti-HIV antibodies. Also disclosed are related methods and compositions. HIV causes acquired immunodeficiency syndrome (AIDS), a condition in humans characterized by clinical features including wasting syndromes, central nervous system degeneration and profound immunosuppression that results in life-threatening opportunistic infections and malignancies. Since its discovery in 1981, HIV type 1 (HIV-1) has led to the death of at least 25 million people worldwide. |
| FILED | Thursday, September 09, 2021 |
| APPL NO | 17/470184 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/1045 (20130101) Original (OR) Class C07K 16/1063 (20130101) C07K 2317/21 (20130101) C07K 2317/33 (20130101) C07K 2317/34 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16111 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002391 | Nussenzweig et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Rockefeller University (New York, New York); California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | The Rockefeller University (New York, New York); California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Michel Nussenzweig (New York, New York); Pamela J. Bjorkman (La Canada Flintridge, California); Louise Scharf (Porter Ranch, California); Johannes Scheid (New York, New York) |
| ABSTRACT | The present invention relates to broadly neutralizing anti-HIV-1 antibodies and isolated antigens. Also disclosed are related methods and compositions. |
| FILED | Friday, September 10, 2021 |
| APPL NO | 17/471573 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/21 (20130101) A61K 39/42 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) Peptides C07K 14/005 (20130101) C07K 16/1063 (20130101) Original (OR) Class C07K 2299/00 (20130101) C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/55 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16111 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56988 (20130101) G01N 2333/162 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002399 | VOGEL et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, Baltimore (Baltimore, Maryland); The United Stated of America, as represented by the Secretary, Departmnet of Health and Human Servic (Besthesda, Maryland) |
| ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland); The United Stated of America, as represented by the Secretary, Departmnet of Health and Human Servic (Bethesda, Maryland) |
| INVENTOR(S) | Stefanie N VOGEL (Columbia, Maryland); Kari Ann SHIREY (Cockeysville, Maryland); Frank CUTTITTA (Adamstown, Maryland) |
| ABSTRACT | Gastrin-releasing peptide (GRP) is a neuroendocrine peptide that acts as a novel contributor to the inflammatory response to influenza infection. Thus, inhibition of GRP or antagonizing the GRP receptor (GRPR) during influenza infection represents a novel therapeutic approach to mitigating lung damage. The present invention encompasses methods of treatment based on these novel findings and observations. |
| FILED | Tuesday, September 10, 2019 |
| APPL NO | 17/274564 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/122 (20130101) A61K 31/505 (20130101) A61K 31/4245 (20130101) A61K 38/22 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) A61P 29/00 (20180101) A61P 31/16 (20180101) Peptides C07K 16/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002400 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); The General Hospital Corporation dba Massachusetts General Hospital (Boston, Massachusetts); University of Edinburgh (Midlothian, United Kingdom) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bo Li (Cambridge, Massachusetts); Nir Hacohen (Boston, Massachusetts); J. Kenneth Baillie (Midlothian, United Kingdom) |
| ABSTRACT | Methods of treating influenza A are provided, comprising administering to a subject at least one agent selected from a WDR7 inhibitor, a CCDC115 inhibitor, a TMEM199 inhibitor, and a CMTR1 inhibitor. |
| FILED | Friday, September 24, 2021 |
| APPL NO | 17/484995 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/16 (20180101) Peptides C07K 16/18 (20130101) C07K 16/28 (20130101) Original (OR) Class C07K 16/40 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1137 (20130101) C12N 15/1138 (20130101) C12N 2310/11 (20130101) C12N 2310/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002429 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Huiping Liu (Chicago, Illinois); Xia Liu (Chicago, Illinois); Valery Adorno-Cruz (Chicago, Illinois); Rokana Taftaf (Chicago, Illinois) |
| ABSTRACT | Disclosed are methods for treating cancer in a subject. The methods typically include administering to the subject a therapeutic agent that inhibits aggregation of tumor cells. |
| FILED | Thursday, October 24, 2019 |
| APPL NO | 17/309115 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) Peptides C07K 16/2821 (20130101) C07K 16/2863 (20130101) C07K 16/2884 (20130101) Original (OR) Class C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002646 | Han et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Texas A and M University System (College Station, Texas); Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Arum Han (College Station, Texas); Sungjin Kim (Bryan, Texas); Ramkumar Menon (League City, Texas); Lauren Richardson (College Station, Texas); Ourlad Alzeus Tantengco (Bataan, Philippines) |
| ABSTRACT | In an embodiment, the present disclosure pertains to an organ-chip model having a plurality of cell culture chambers connected through arrays of microfluidic channels. In some embodiments, each cell culture chamber of the plurality of cell culture chambers include an inlet and an outlet. In some embodiments, the inlet is configured to receive at least one of a cell, cell media, or a cell stimulant. In some embodiments, at least one outlet is configured to collect effluent. In some embodiments, the organ-chip model can include, without limitation, an organ-chip model of amnion membrane, an organ-chip model of a feto-maternal interface (fetal membrane-decidua parietalis), an organ-chip model of a feto-maternal interface (placenta-decidua interface), an organ-chip model of a cervix, and combinations thereof. In some embodiments, the organ-chip model is an interconnected organ-chip model having a combination of one or more organ-chip models with interconnected cell culture chambers. |
| FILED | Wednesday, June 02, 2021 |
| APPL NO | 17/336730 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) Original (OR) Class C12M 23/16 (20130101) C12M 25/02 (20130101) C12M 29/10 (20130101) C12M 33/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002672 | Kim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The USA, as represented by the Secretary, Department of Health and Human Services. (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yong Chan Kim (Rockville, Maryland); Ethan Shevach (Rockville, Maryland) |
| ABSTRACT | The present invention provides methods for producing cell populations enriched for stable, regulatory T cells (Tregs). In particular, the invention relates to methods for culturing T cells such that the final culture is enriched for stable, regulatory T cells. It also relates to methods for stabilizing regulatory T cells. Also provided are compositions enriched for stable, regulatory T cells, which are useful for treating individuals in need of such treatment. The methods and compositions disclosed herein can also be used to treat an individual suffering from an immune-mediated disease. |
| FILED | Friday, July 09, 2021 |
| APPL NO | 17/371589 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 2035/124 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 5/0637 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002718 | Joung et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | J. Keith Joung (Winchester, Massachusetts); Peter Cabeceiras (Boston, Massachusetts) |
| ABSTRACT | Tunneling nanotube (TNT) cells, comprising a TNT promoting factor (TPF); and a biomolecule cargo overexpressed by the TNT cell, and methods of use thereof for delivery of the biomolecule cargo from TNT cells to neighboring cells. |
| FILED | Wednesday, June 23, 2021 |
| APPL NO | 17/355638 |
| CURRENT CPC | Peptides C07K 14/4705 (20130101) C07K 2319/81 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0603 (20130101) C12N 5/0636 (20130101) C12N 15/111 (20130101) Original (OR) Class C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002730 | Kortylewski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | City of Hope (Duarte, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Marcin Tomasz Kortylewski (Monrovia, California); Piotr Marek Swiderski (San Dimas, California) |
| ABSTRACT | Disclosed herein, inter alia, are oligonucleotide inhibitors of the Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells (NF-κB) signaling pathway and methods of use thereof. |
| FILED | Friday, August 23, 2019 |
| APPL NO | 17/269229 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/548 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/117 (20130101) Original (OR) Class C12N 2310/13 (20130101) C12N 2310/17 (20130101) C12N 2310/315 (20130101) C12N 2310/3519 (20130101) C12N 2320/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002732 | KARTHIKEYAN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF SOUTH CAROLINA (COLUMBIA, South Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | MYTHREYE KARTHIKEYAN (COLUMBIA, South Carolina); PRIYANKA SINGH (COLUMBIA, South Carolina) |
| ABSTRACT | Contact of endothelial cells with inhibitors of inhibin and/or the alpha-subunit of inhibin can be utilized to modify the activity of endothelial cell expression products including SMAD1/5. Methods can also include inhibiting ALK1 and/or endoglin as components of inhibin-activated pathway of SMAD1/5 signaling. Methods can be combined with other anti-angiogenesis therapies such as anti-VEGF therapies. Methods can be utilized in treatment of inhibin-expressing cancers (e.g., ovarian cancer, pancreatic cancer) as well as other pathologies such as pre-eclampsia and PCOS. |
| FILED | Thursday, September 16, 2021 |
| APPL NO | 17/476803 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1136 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/531 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002753 | Qi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Lei S. Qi (Stanford, California); Haifeng Wang (Stanford, California) |
| ABSTRACT | Provided herein are systems and methods for the controlling the spatial positioning of a target polynucleotide in a compartment of a cell. |
| FILED | Friday, February 19, 2021 |
| APPL NO | 17/180535 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/85 (20130101) C12N 15/90 (20130101) Original (OR) Class C12N 15/111 (20130101) C12N 2310/20 (20170501) C12N 2320/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002794 | Druley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Todd E. Druley (St. Louis, Missouri); Andrew Young (St. Louis, Missouri) |
| ABSTRACT | The present disclosure encompasses methods of error corrected sequencing (ECS) that enable detection of very rare mutations well below the error rate of convention next generation sequencing (NGS). Further, the methods disclosed herein enable multiplex targeting of genomic DNA. |
| FILED | Wednesday, September 22, 2021 |
| APPL NO | 17/448472 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6855 (20130101) C12Q 1/6858 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 1/6883 (20130101) C12Q 1/6886 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002804 | Hare |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MIAMI (Miami, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joshua M. Hare (Miami Beach, Florida) |
| ABSTRACT | The present disclosure is directed to methods for determining responsiveness to cell therapy in a subject suffering from a cardiovascular disorder (e.g., cardiomyopathy) and methods of treating subjects suffering from a cardiovascular disorder. |
| FILED | Friday, November 08, 2019 |
| APPL NO | 17/291556 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002809 | Horvath et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Stefan Horvath (Los Angeles, California); Ake Tzu-Hui Lu (Los Angeles, California) |
| ABSTRACT | The invention disclosed herein is a DNA methylation-based estimator of human telomere length (“DNAmTL”) that is based on 140 CpGs, and is applicable across the entire age spectrum. DNAmTL is even more strongly associated with chronological age than is measured TL (r˜−0.75 for DNAmTL versus r˜−0.35 for TL) and outperforms the latter in predicting i) time-to-death (P=4.1E-15), ii) time-to-coronary heart disease (p=6.6E-5), and iii) time-to-congestive heart failure (p=3.5E-6); all of which were corroborated with large sets of blood methylation data (N=6,850). DNAmTL is also associated with non-pathological conditions including physical functioning (P=7.6E-3), age-at-menopause (P=0.039), dietary variables (omega 3, fish, vegetable), educational attainment (P=4.3E-6) and income (P=3.1E-5). DNAmTL is an attractive molecular biomarker of aging due to its superior performance to measured TL, its intuitive interpretation of telomere length, its ease of use in vivo and in vitro, and its robustness. |
| FILED | Wednesday, February 05, 2020 |
| APPL NO | 17/419641 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6881 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/154 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002810 | Xu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wake Forest University Health Sciences (Winston-Salem, North Carolina); Karolinska Institutet Innovations AB (Stockholm, Sweden); The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jianfeng Xu (Clemmons, North Carolina); S. Lilly Zheng (Clemmons, North Carolina); Henrik Grönberg (Umea, Sweden); William B. Isaacs (Glyndon, Maryland) |
| ABSTRACT | The present invention provides a method of identifying a subject as having an increased risk of developing prostate cancer, comprising detecting in the subject the presence of various polymorphisms associated with an increased risk of developing prostate cancer. |
| FILED | Wednesday, February 17, 2021 |
| APPL NO | 17/177568 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/172 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002816 | THOMPSON-ELLIOTT et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Center for Cancer Research and Therapeutic Development, Clark Atlanta University (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bethtrice THOMPSON-ELLIOTT (Kennesaw, Georgia); Shafiq Ahmed KHAN (Mableton, Georgia); Ana Cecilia MILLENA (Austell, Georgia) |
| ABSTRACT | This disclosure generally relates to the development of therapeutic and chemo-preventative strategies to prostate cancer initiation and carcinogenesis. Specifically, the disclosure relates to the role the JunD transcription factor plays in the deregulation of cell proliferation. The disclosure relates to a novel method of identifying JunD target genes and inhibiting the expression and/or function of the JunD target genes to interfere with the regulation of cancer cell proliferation and early stages of carcinogenesis. |
| FILED | Thursday, October 31, 2019 |
| APPL NO | 17/293003 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/551 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220003731 | DU et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Florida Atlantic University Board of Trustees (Boca Raton, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | E DU (Boca Raton, Florida); Yuhao QIANG (Boca Raton, Florida); Darryl DIEUJUSTE (North Miami, Florida); Jia LIU (Boca Raton, Florida) |
| ABSTRACT | An exemplary portable automated device is developed for in vitro testing of blood vascular occlusion as a result of sickle cell disease. The portable automated device may be controlled by a computer (e.g., smartphone) application. Calibration of the portable device may be performed using a component of known impedance value. With the developed portable automated device, analysis may be performed on sickle cell samples on a microfluidic platform that mimics the structure of human capillaries. Significant differences in cell impedance signals may be observed between sickle cells and normal cells, as well as between sickle cells under hypoxia and normoxia conditions. |
| FILED | Thursday, May 06, 2021 |
| APPL NO | 17/313235 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4077 (20130101) G01N 33/0022 (20130101) Original (OR) Class G01N 33/491 (20130101) G01N 33/6893 (20130101) G01N 2001/4088 (20130101) G01N 2800/224 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220003776 | Lara Gutierrez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Juanita M. Lara Gutierrez (Cambridge, Massachusetts); Maier S. Avendano Amado (Cambridge, Massachusetts); Peng Yin (Cambridge, Massachusetts) |
| ABSTRACT | This disclosure provides methods and compositions for detecting intramolecular and intermolecular interactions, such as protein-protein interactions. These methods detect such interactions at sub-diffraction distances, and thus are referred to as super-resolution detection and imaging methods. |
| FILED | Thursday, July 08, 2021 |
| APPL NO | 17/370925 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) C12Q 1/6897 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/6845 (20130101) Original (OR) Class G01N 2458/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220003777 | Bertozzi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Carolyn R. Bertozzi (Menlo Park, California); Stacy A. Malaker (Menlo Park, California); Kayvon Pedram (Stanford, California); Dayeon Shon (Stanford, California) |
| ABSTRACT | The present disclosure provides compositions and methods involving the use of mucin-specific proteases for mucin-specific cleavage, labeling, and/or enrichment of mucin domain glycoproteins. Also provided are methods for the analysis of mucin-domain glycoproteins useful in glycomapping of mucin glycosites and their associated glycoforms. Provided compositions and methods are also useful for selective cleavage, release, and enrichment of mucins from cell and tissue samples, for the study of native mucin biology, and for the detection and analysis of mucins that are aberrantly expressed in various conditions, including cancer. |
| FILED | Thursday, November 07, 2019 |
| APPL NO | 17/291376 |
| CURRENT CPC | Enzymes C12Y 402/02001 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/6818 (20130101) G01N 33/6848 (20130101) Original (OR) Class G01N 2333/95 (20130101) G01N 2333/988 (20130101) G01N 2333/4725 (20130101) G01N 2400/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220005547 | Ye et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Chun Ye (San Francisco, California); Meena SUBRAMANIAM (Fremont, California); Rachel GATE (San Francisco, California); Sasha TARG (San Francisco, California) |
| ABSTRACT | Techniques for multiplexed droplet-based sequencing using natural genetic barcodes. An exemplary technique determining a unique variant combination associated with each subject from a plurality of subjects, determining a presence of a plurality of target variants in sequence reads grouped into partitions, and performing a sample demultiplexing and multiplet detection technique (demuxlet) on the sequence reads to: (i) remove sequence reads for partitions that are determined to be doublets based on a first statistical comparison of the unique variant combination associated with each subject and the plurality of target variants in the sequence reads, and (ii) assign a subject from the plurality of subjects to the remaining partitions remaining based on a second statistical comparison of the unique variant combination associated with the each subject from the plurality of subjects and the plurality of target variants in the sequence reads. |
| FILED | Tuesday, December 10, 2019 |
| APPL NO | 17/294977 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) C12Q 1/6874 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/20 (20190201) G16B 20/20 (20190201) Original (OR) Class G16B 25/10 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220005681 | Cooks et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert Graham Cooks (West Lafayette, Indiana); Alan Keith Jarmusch (Lafayette, Indiana); Valentina Pirro (West Lafayette, Indiana) |
| ABSTRACT | The invention generally relates to systems and methods for sample analysis using swabs. In certain aspects, the invention provides systems that include a probe having a conductive proximal portion coupled to a porous material at a distal portion of the probe that is configured to retain a portion of a sample that has contacted the porous material, and a mass spectrometer having an inlet. The system is configured such that the porous material at a distal portion of the probe is aligned over the inlet of the mass spectrometer. |
| FILED | Monday, April 05, 2021 |
| APPL NO | 17/222194 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/7282 (20130101) A61B 5/14503 (20130101) A61B 10/02 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 13/38 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/72 (20130101) G01N 2001/028 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/165 (20130101) H01J 49/0409 (20130101) H01J 49/0459 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220006221 | van Welie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ingrid van Welie (Newton, Massachusetts); Leonard Kogos (Salem, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ingrid van Welie (Newton, Massachusetts); Leonard Kogos (Salem, Massachusetts) |
| ABSTRACT | The invention relates to an apparatus, system and method for a direct flex cable to flex cable connection, with guides through which the said flex cables are aligned upon insertion and a pressing mechanism which in its latched state perfectly aligns corresponding guides to each other and by extension also aligns corresponding contact pads on the flex cables, and brings them into firm electrical contact. |
| FILED | Friday, July 03, 2020 |
| APPL NO | 16/920503 |
| CURRENT CPC | Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 12/79 (20130101) Original (OR) Class H01R 12/91 (20130101) H01R 12/774 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220006557 | Pierson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Timothy J. Pierson (Hanover, Vermont); Ronald Peterson (Brattleboro, Vermont); David F. Kotz (Brattleboro, Vermont) |
| ABSTRACT | Apparatuses that provide for secure wireless communications between wireless devices under cover of one or more jamming signals. Each such apparatus includes at least one data antenna and at least one jamming antenna. During secure-communications operations, the apparatus transmits a data signal containing desired data via the at least one data antenna while also at least partially simultaneously transmitting a jamming signal via the at least one jamming antenna. When a target antenna of a target device is in close proximity to the data antenna and is closer to the data antenna than to the jamming antenna, the target device can successfully receive the desired data contained in the data signal because the data signal is sufficiently stronger than the jamming signal within a finite secure-communications envelope due to the Inverse Square Law of signal propagation. Various related methods and machine-executable instructions are also disclosed. |
| FILED | Friday, September 17, 2021 |
| APPL NO | 17/477718 |
| CURRENT CPC | Transmission H04B 1/1009 (20130101) Secret Communication; Jamming of Communication H04K 3/42 (20130101) Original (OR) Class H04K 3/43 (20130101) Wireless Communication Networks H04W 4/80 (20180201) H04W 12/033 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20220000138 | Harris et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Gabriel Keith Harris (Raleigh, North Carolina); Matthew Alan Robinson Sharp (Raleigh, North Carolina) |
| ABSTRACT | Disclosed is a composition comprising a dispersion of an ingredient in a fat matrix, optionally wherein the ingredient is selected from the group comprising a macronutrient, a micronutrient, a dietary bioactive, a pharmaceutical ingredient, and combinations thereof, further optionally, wherein the dispersion is a uniform dispersion. In some embodiments, the macronutrient is a protein, a carbohydrate, a second type of fat in addition to the one forming the primary fat matrix, water, or a combination thereof. Also disclosed is a process for preparing a dispersion of an ingredient in a fat matrix, optionally wherein the ingredient is selected from the group comprising a macronutrient, a micronutrient, a dietary bioactive, a pharmaceutical ingredient, and combinations thereof, further optionally, wherein the dispersion is a uniform dispersion. In some embodiments, the process comprises: (a) heating the fat matrix to provide a melted or heat-plasticized fat matrix; (b) mixing the ingredient into the melted or heat-plasticized fat matrix, optionally wherein the ingredient comprises particles; and (c) cooling the mixture formed in step (b) to form the composition comprising a dispersion of an ingredient in a fat matrix, optionally wherein the ingredient is selected from the group comprising a macronutrient, a micronutrient, a dietary bioactive, a pharmaceutical ingredient, and combinations thereof, further optionally, wherein the dispersion is a uniform dispersion. |
| FILED | Monday, November 11, 2019 |
| APPL NO | 17/291474 |
| CURRENT CPC | Edible Oils or Fats, e.g Margarines, Shortenings, Cooking Oils A23D 9/04 (20130101) A23D 9/06 (20130101) Original (OR) Class A23D 9/007 (20130101) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/19 (20160801) A23L 33/115 (20160801) A23L 33/125 (20160801) A23L 33/185 (20160801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220000486 | Williams et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Timothy K. Williams (Winston-Salem, North Carolina); Lucas Paul Neff (Winston-Salem, North Carolina) |
| ABSTRACT | An endovascular occlusion device. The endovascular occlusion device (300) has a balloon (306) and a catheter (304). The catheter (304) has a distal end (308), a proximal end, and a lumen (318) extending therebetween. The balloon (306) is positioned proximate to the distal end (308) of the catheter (304) and has a deflated state and an inflated state. The catheter (304) further includes a plurality of ports (314) proximate to a proximal end of the balloon (306). Each port (314) extends through a wall of the catheter (304) such that surface (316) of the catheter (304) is in fluid communication with the lumen (318) of the catheter (304). A flow restrictor (324) is positioned within, and is in sliding relation with, the lumen (318) of the catheter (304). Movement of the flow restrictor (324) is configured to close one or more ports (314) of the plurality so as to limit blood flow through the lumen (318) of the catheter (304). |
| FILED | Wednesday, May 12, 2021 |
| APPL NO | 17/318512 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/1204 (20130101) A61B 17/12036 (20130101) Original (OR) Class A61B 17/12109 (20130101) A61B 17/12136 (20130101) A61B 2017/1205 (20130101) A61B 2090/061 (20160201) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/10 (20130101) A61M 25/0097 (20130101) A61M 29/02 (20130101) A61M 2025/1095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220000768 | Freeman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (, None) |
| INVENTOR(S) | William Freeman (Del Mar, California); Michael J. Sailor (La Jolla, California); Lingyun Cheng (San Diego, California); Frederique Cunin (Montpellier, France); Emily Anglin (San Diego, California); Yang Yang Li (Hong Kong, China Hong Kong) |
| ABSTRACT | A minimally invasive controlled drug delivery system for delivering a particular drug or drugs to a particular location of the eye, the system including a porous film template having pores configured and dimensioned to at least partially receive at least one drug therein, and wherein the template is dimensioned to be delivered into or onto the eye. |
| FILED | Monday, November 06, 2017 |
| APPL NO | 15/804856 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/0017 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) Original (OR) Class A61K 9/0051 (20130101) A61K 47/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001197 | Huettemann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wayne state University (Detroit, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Maik Huettemann (Grosse Pointe Park, Michigan); Mauri ce-Andre Recanati (New York, New York); Thomas H. Sanderson (Plymouth, Michigan) |
| ABSTRACT | A method and apparatus for minimizing tissue adhesion in a tissue of a subject includes applying light, to the tissue, that reduces at least one adhesion marker in the tissue, the light having wavelengths in at least one of a first wavelength range of 730-770 nm and a second wavelength range of 930-970 nm, wherein the at least one adhesion marker includes at least one of a transforming growth factor beta 1 (TGF-β1), a vascular endothelial growth factor, (VEGF), and a collagen alpha-1(I) chain (COL|α|), and wherein the light is free of wavelengths that increase the at least one adhesion marker. |
| FILED | Thursday, October 31, 2019 |
| APPL NO | 17/290577 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 5/0603 (20130101) A61N 5/0616 (20130101) Original (OR) Class A61N 2005/063 (20130101) A61N 2005/0652 (20130101) A61N 2005/0659 (20130101) A61N 2005/0663 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001378 | ZENHAUSERN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona); The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Frederic ZENHAUSERN (Phoenix, Arizona); Brett DUANE (Phoenix, Arizona); Jian GU (Phoenix, Arizona); Alan NORDQUIST (Phoenix, Arizona); David BRENNER (New York, New York); Mikhail REPIN (New York, New York) |
| ABSTRACT | Provided herein are methods and related devices for preprocessing a biological sample during transit. The method may comprise the steps of: storing a biological sample in a storage container having walls that defines a storage volume; transporting the storage container with the stored biological sample to a sample processing facility; controlling one or more storage container parameters during the transporting step to initiate preprocessing of the biological sample; wherein the controlling step improves a processing parameter at the sample processing facility. |
| FILED | Thursday, December 05, 2019 |
| APPL NO | 17/293707 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50 (20130101) Original (OR) Class B01L 2200/185 (20130101) B01L 2300/18 (20130101) B01L 2300/021 (20130101) B01L 2300/023 (20130101) B01L 2300/0663 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001597 | Sodano et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents Of The University Of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Henry A. Sodano (Ann Arbor, Michigan); Ruowen Tu (Ann Arbor, Michigan) |
| ABSTRACT | The disclosure relates to methods of forming three-dimensional (3D) polymeric articles and additive manufacturing apparatuses for the same. The methods include providing a polymeric solution comprising a polymer dissolved in a solvent; providing a non-solvent, wherein the solvent is miscible in the non-solvent, and the polymer is insoluble in the non-solvent; and injecting the polymeric solution into the non-solvent in a pre-determined 3D pattern to provide a 3D polymeric article. |
| FILED | Thursday, July 01, 2021 |
| APPL NO | 17/365099 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/106 (20170801) Original (OR) Class B29C 64/295 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2101/10 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 40/20 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001983 | Groen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Skyworks Aeronautics Corp. (Salt Lake City, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Groen (Murray, Utah) |
| ABSTRACT | A precision delivery vehicle having a vehicle body assembly, a fixed wing system, a rotor system and a guidance system. The vehicle body assembly can retain a payload. The fixed wing system includes first and second wings coupled to the vehicle body for fixed wing flight. The rotor system includes a mast structure, a rotor hub rotatable about the mast structure and at least two rotor blades coupled to the rotor hub and rotatable with the rotor hub relative to the mast structure. The at least two rotor blades are movable between a collapsed configuration and a deployed configuration. In the collapsed configuration, the precision delivery vehicle is in fixed wing flight. Upon placement of the at least two rotor blades into the deployed configuration, the precision delivery vehicle is placed into rotative flight. The guidance system is structurally configured to direct the precision delivery vehicle to a target. |
| FILED | Tuesday, September 14, 2021 |
| APPL NO | 17/475207 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 3/56 (20130101) B64C 29/02 (20130101) B64C 39/024 (20130101) B64C 2201/102 (20130101) B64C 2201/108 (20130101) B64C 2201/128 (20130101) B64C 2201/206 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 1/12 (20130101) Original (OR) Class B64D 17/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002238 | FAIRBANKS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Carolyn A. FAIRBANKS (Minneapolis, Minnesota); Herbert T. NAGASAWA (Minneapolis, Minnesota); George L. WILCOX (Minneapolis, Minnesota); Cristina D. PETERSON (Minneapolis, Minnesota); Kelley F. KITTO (Minneapolis, Minnesota) |
| ABSTRACT | The invention provides a compound of formula I and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the formula I compounds, as well as methods of using such as therapeutic agents for the treatment of pain-related disorders and diseases and in combination with other therapeutic agents. |
| FILED | Wednesday, November 06, 2019 |
| APPL NO | 17/291345 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 279/14 (20130101) C07C 279/24 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002429 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Huiping Liu (Chicago, Illinois); Xia Liu (Chicago, Illinois); Valery Adorno-Cruz (Chicago, Illinois); Rokana Taftaf (Chicago, Illinois) |
| ABSTRACT | Disclosed are methods for treating cancer in a subject. The methods typically include administering to the subject a therapeutic agent that inhibits aggregation of tumor cells. |
| FILED | Thursday, October 24, 2019 |
| APPL NO | 17/309115 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) Peptides C07K 16/2821 (20130101) C07K 16/2863 (20130101) C07K 16/2884 (20130101) Original (OR) Class C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002497 | ZHANG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Notre Dame du Lac (South Bend, Indiana); Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | University of Notre Dame du Lac (South Bend, Indiana); Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Yizhou ZHANG (South Bend, Indiana); William A. PHILLIP (South Bend, Indiana); Matthew J. WEBBER (South Bend, Indiana); Bryan W. BOUDOURIS (West Lafayette, Indiana) |
| ABSTRACT | A highly permeable sorbent platform based on polysulfone and polystyrene-b-poly(acrylic acid) composite membranes. The membranes possess a fully interconnected network of poly(acrylic acid)-lined pores, which enables the surface chemistry to be tailored through sequential attachment of polyethyleneimine moieties and metal-binding terpyridine ligands. The polyethyleneimine moieties increase the saturation capacity, while the addition of terpyridine enables high-affinity binding to a diversity of transition metal ions. This membrane platform removes such metal contaminants from solution. The metal capture performance of the functionalized membranes persists even in high concentrations of competitive ions. Also, fluorescence quenching of the terpyridine moiety upon metal ion complexation offers an in-situ probe to monitor the extent of sorbent saturation. The permeability, capacity, and affinity of these membranes, with high-density display of a metal-binding ligand, offer a chemically tailored platform to address the challenges that arise in ensuring clean water. |
| FILED | Wednesday, October 30, 2019 |
| APPL NO | 17/289647 |
| CURRENT CPC | Separation B01D 67/0011 (20130101) B01D 67/0013 (20130101) B01D 67/0093 (20130101) B01D 69/02 (20130101) B01D 69/12 (20130101) B01D 69/147 (20130101) B01D 71/40 (20130101) B01D 71/60 (20130101) B01D 71/68 (20130101) B01D 71/80 (20130101) B01D 2325/02 (20130101) B01D 2325/34 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 39/04 (20130101) B01J 39/19 (20170101) B01J 47/12 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/44 (20130101) C02F 2101/20 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 81/024 (20130101) Original (OR) Class Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/2268 (20130101) C08J 5/2287 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002554 | AIZENBERG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joanna AIZENBERG (Cambridge, Massachusetts); Nicolas VOGEL (Erlangen, Germany); Ian BURGESS (Toronto, Canada); Mathias KOLLE (Hull, Massachusetts); Tanya SHIRMAN (Arlington, Massachusetts); Stefanie UTECH (Erlangen, Germany); Katherine Reece PHILLIPS (Cambridge, Massachusetts); David A. WEITZ (Bolton, Massachusetts); Natalie KOAY (Somerville, Massachusetts) |
| ABSTRACT | A pigment comprising a plurality of photonic crystal particles dispersed in a medium, each photonic crystal particles containing a plurality of spectrally selective absorbing components dispersed within each photonic crystal particle that selectively absorb electromagnetic radiation without substantially absorbing electromagnetic radiation near a resonant wavelength of each photonic crystal particle, wherein each photonic crystal particle has a predetermined minimum number of repeat units of a photonic crystal structure, wherein the predetermined minimum number of repeat units is related to the resonant wavelength, the full-width at half maximum of the resonant wavelength, and the refractive index contrast in the photonic crystal. |
| FILED | Thursday, September 16, 2021 |
| APPL NO | 17/476950 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/19 (20130101) A61K 8/25 (20130101) A61K 8/29 (20130101) A61K 8/0283 (20130101) A61K 8/8176 (20130101) A61K 2800/43 (20130101) A61K 2800/412 (20130101) A61K 2800/5922 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 1/02 (20130101) A61Q 1/06 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/64 (20130101) Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black; C09C 1/62 (20130101) C09C 1/0081 (20130101) Original (OR) Class C09C 3/06 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 17/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002737 | THESS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CureVac AG (Tübingen, Germany) |
| ASSIGNEE(S) | CureVac AG (Tübingen, Germany) |
| INVENTOR(S) | Andreas THESS (Kusterdingen, Germany); Thomas SCHLAKE (Gundelfingen, Germany); Stefanie GRUND (Stuttgart, Germany) |
| ABSTRACT | The invention relates to an artificial nucleic acid molecule comprising an open reading frame and a 3′-UTR comprising at least one poly(A) sequence or a polyadenylation signal. The invention further relates to a vector comprising the artificial nucleic acid molecule comprising an open reading frame and a 3′-UTR comprising at least one poly(A) sequence or a polyadenylation signal, to a cell comprising the artificial nucleic acid molecule or the vector, to a pharmaceutical composition comprising the artificial nucleic acid molecule or the vector and to a kit comprising the artificial nucleic acid molecule, the vector and/or the pharmaceutical composition. The invention also relates to a method for increasing protein production from an artificial nucleic acid molecule and to the use of a 3′-UTR for a method for increasing protein production from an artificial nucleic acid molecule. Moreover, the invention concerns the use of the artificial nucleic acid molecule, the vector, the kit or the pharmaceutical composition as a medicament, as a vaccine or in gene therapy. |
| FILED | Friday, August 20, 2021 |
| APPL NO | 17/408332 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/145 (20130101) A61K 39/205 (20130101) A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/67 (20130101) Original (OR) Class C12N 15/68 (20130101) C12N 15/85 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002758 | Barton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hazel A. Barton (Akron, Ohio); Matthew Jennings (Akron, Ohio); George Breley (Akron, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hazel A. Barton (Akron, Ohio); Matthew Jennings (Akron, Ohio); George Breley (Akron, Ohio) |
| ABSTRACT | A method for sequestering CO2 and creating precipitated calcium carbonates includes: (a) providing a liquid calcification medium including: a nutrient broth including water and a yeast extract, a carbon source selected from calcium carboxylic acids and calcium dicarboxylic acids and mixtures thereof, and bacteria that naturally express the chaA gene; (b) introducing CO2 to the liquid calcification medium; and (c) allowing microbial induced carbonate precipitation of calcium carbonate, thereby sequestering at least some of the CO2 introduced in said step of introducing |
| FILED | Monday, May 03, 2021 |
| APPL NO | 17/306189 |
| CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 3/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002790 | KISHI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Jocelyn Yoshiko KISHI (Boston, Massachusetts); Sinem K. SAKA (Allston, Massachusetts); Ninning LIU (Boston, Massachusetts); Peng YIN (Boston, Massachusetts) |
| ABSTRACT | Provided herein are methods and compositions related to nucleic acid barcoding. In some aspects, provided herein are methods and compositions for writing, storing, reading, and resetting data, for example, using photocrosslinking and/or a substrate or compressible hydrogel. |
| FILED | Friday, November 01, 2019 |
| APPL NO | 17/289889 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6834 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002810 | Xu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wake Forest University Health Sciences (Winston-Salem, North Carolina); Karolinska Institutet Innovations AB (Stockholm, Sweden); The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jianfeng Xu (Clemmons, North Carolina); S. Lilly Zheng (Clemmons, North Carolina); Henrik Grönberg (Umea, Sweden); William B. Isaacs (Glyndon, Maryland) |
| ABSTRACT | The present invention provides a method of identifying a subject as having an increased risk of developing prostate cancer, comprising detecting in the subject the presence of various polymorphisms associated with an increased risk of developing prostate cancer. |
| FILED | Wednesday, February 17, 2021 |
| APPL NO | 17/177568 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/172 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220003119 | Ghigliotty et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Jaime G. Ghigliotty (Cabo Rojo, Puerto Rico); David J. Candelori (Glastonbury, Connecticut); San Quach (Southington, Connecticut) |
| ABSTRACT | An airfoil for a gas turbine engine is disclosed. In various embodiments, the airfoil includes a cooling passage; an outer wall separating a core flow path from the cooling passage; a diffuser in fluid communication with the cooling passage and opening into the core flow path, the diffuser being characterized by a linear ridge on a downstream end of the diffuser; and a thermal barrier coating covering the outer wall and the linear ridge. |
| FILED | Thursday, July 02, 2020 |
| APPL NO | 16/920014 |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/186 (20130101) Original (OR) Class F01D 25/12 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/12 (20130101) F05D 2240/14 (20130101) F05D 2240/35 (20130101) F05D 2250/12 (20130101) F05D 2260/202 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220003120 | Quach et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | San Quach (East Hartford, Connecticut); Tracy A. Propheter-Hinckley (Manchester, Connecticut); Steven Bruce Gautschi (Naugatuck, Connecticut) |
| ABSTRACT | A component for a gas turbine engine includes, among other things, an airfoil that includes a pressure sidewall and a suction sidewall that meet together at both a leading edge and a trailing edge, the airfoil extending radially from a platform to a tip, a tip pocket formed in the tip and terminating prior to the trailing edge, and one or more heat transfer augmentation devices formed in the tip pocket. |
| FILED | Thursday, September 23, 2021 |
| APPL NO | 17/482478 |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/20 (20130101) F01D 5/147 (20130101) F01D 5/186 (20130101) F01D 5/187 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2260/202 (20130101) F05D 2260/221 (20130101) F05D 2260/2212 (20130101) F05D 2260/2214 (20130101) F05D 2260/22141 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220003221 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Na Li (Richardson, Texas); Carter S. Haines (Murphy, Texas); Marco D. Lima (Richardson, Texas); Monica Jung DeAndrade (Richardson, Texas); Shaoli Fang (Richardson, Texas); Jiyoung Oh (Richardson, Texas); Mikhail E. Kozlov (Dallas, Texas); Dongseok Suh (Plano, Texas); Ray H. Baughman (Dallas, Texas) |
| ABSTRACT | Actuators (artificial muscles) comprising twist-spun nanofiber yarn or twist-inserted polymer fibers generate actuation when powered electrically, photonically, chemically, thermally, by absorption, or by other means. These artificial muscles utilize polymer fibers non-coiled or coiled yarns and can be either neat or comprising a guest. Devices comprising these artificial muscles are also described. In some embodiments, thermally-powered polymer fiber torsional actuator has a twisted, chain-oriented polymer fiber that has a first degree of twist at a first temperature and a second degree of twist at a second temperature in which the bias angles of the first degree and second degree of twist are substantially different. |
| FILED | Tuesday, September 21, 2021 |
| APPL NO | 17/480635 |
| CURRENT CPC | Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0007 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 6/00 (20130101) Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads D02G 3/02 (20130101) D02G 3/26 (20130101) D02G 3/448 (20130101) Braiding or Manufacture of Lace, Including Bobbin-net or Carbonised Lace; Braiding Machines; Braid; Lace D04C 1/02 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2401/046 (20130101) D10B 2401/061 (20130101) D10B 2509/00 (20130101) Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 7/06 (20130101) Original (OR) Class Electric Machines Not Otherwise Provided for H02N 10/00 (20130101) H02N 11/006 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2925 (20150115) Y10T 428/249921 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220003353 | Gorodetsky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Alon A. Gorodetsky (Irvine, California); Steven R. Jim (Hillsboro, Oregon); George Stiubianu (Iasi, Romania); Erica Leung (Piedmont, California); Kyle Naughton (Laguna Beach, California); Priyam Patel (Irvine, California); Maurizio Follador (Givoletto, Italy); Emil Karshalev (San Diego, California) |
| ABSTRACT | Composite materials with adjustable spectral properties comprised of IR-reflecting micro-domains overlaying an IR-transparent elastomeric matrix, and capable of dynamically controlling IR radiation transmission are described, as well as methods of fabrication thereof. Systems with capabilities to regulate IR radiation (including heat) transmission based thereon, and methods of regulating IR radiation transmission (including thermal regulation) using the same are also provided. |
| FILED | Wednesday, November 27, 2019 |
| APPL NO | 17/297888 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 41/003 (20130101) B29C 41/04 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2025/08 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/0005 (20130101) C23C 14/16 (20130101) C23C 14/30 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 59/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220003776 | Lara Gutierrez et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Juanita M. Lara Gutierrez (Cambridge, Massachusetts); Maier S. Avendano Amado (Cambridge, Massachusetts); Peng Yin (Cambridge, Massachusetts) |
| ABSTRACT | This disclosure provides methods and compositions for detecting intramolecular and intermolecular interactions, such as protein-protein interactions. These methods detect such interactions at sub-diffraction distances, and thus are referred to as super-resolution detection and imaging methods. |
| FILED | Thursday, July 08, 2021 |
| APPL NO | 17/370925 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) C12Q 1/6897 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/6845 (20130101) Original (OR) Class G01N 2458/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220003824 | Klug et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Christopher A. Klug (Falls Church, Virginia); Stefan Benders, III (New York, New York); Mohadesse Mohammadi (Woodside, New York); Alexej Jerschow (New York, New York) |
| ABSTRACT | Disclosed herein is a method of: providing a circuit having: a rechargeable pouch cell battery comprising lithium and an electrically insulating coating, a first electrical lead in contact with the coating at a first location on the battery, a second electrical lead in contact with the coating at a second location on the battery, a tuning capacitor in parallel to the battery, and an impedance matching capacitor in series with the battery and the tuning capacitor; placing the battery in a magnetic field; applying a radio frequency voltage to the circuit; and detecting a 7Li nuclear magnetic resonance signal in response to the voltage. |
| FILED | Thursday, July 01, 2021 |
| APPL NO | 17/365278 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 24/08 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 31/364 (20190101) G01R 31/392 (20190101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/052 (20130101) H01M 50/105 (20210101) H01M 50/569 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220003894 | SHAPIRO et al. |
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| FUNDED BY |
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| APPLICANT(S) | Sofar Ocean Technologies, Inc. (San Francisco, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Evan SHAPIRO (San Francisco, California); Tim JANSSEN (Montara, California); Pieter SMIT (Stanford, California) |
| ABSTRACT | A computer-implemented method for forecasting weather uses a trained machine learning model to determine the error in a weather forecast, e.g., for a selected ocean region. The machine learning model is configured to determine the predicted forecasting error given the weather forecast and a set of existing conditions. The weather forecast is adjusted using the predicted forecasting error to produce an augmented weather forecast. Training the machine learning model may include the utilization of hindcasting methods. Determination of existing conditions and other modeling may include the use of data from an array of metocean sensor nodes dispersed on a body of water. |
| FILED | Thursday, September 26, 2019 |
| APPL NO | 17/279477 |
| CURRENT CPC | Meteorology G01W 1/10 (20130101) Original (OR) Class G01W 2203/00 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/0454 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220003978 | Hall |
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| FUNDED BY |
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| APPLICANT(S) | United States of America, as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John M. Hall (Stafford, Virginia) |
| ABSTRACT | A low magnification mode of operation of a multiple field of view optical system is based on off-axis reflective afocal assemblies with a common optical exit pupil and having a common mechanical axis of rotation which provides both field of view switching and image de-roll functions. A reflective afocal switching assembly permits variable fields of view while at the same time providing a common axis and mechanism to achieve an optical de-roll of the image. This complex arrangement provides a relatively large change in magnification for an all-reflective optical system than can image over 0.4-12.0 micron spectrum. |
| FILED | Tuesday, September 21, 2021 |
| APPL NO | 17/480190 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/10 (20130101) G02B 7/1821 (20130101) G02B 17/0636 (20130101) G02B 17/0694 (20130101) Original (OR) Class G02B 26/0816 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220004016 | ROBERTS et al. |
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| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gregory ROBERTS (Pasadena, California); Andrei FARAON (Pasadena, California) |
| ABSTRACT | Methods and devices to split electromagnetic waves across broad bandwidths in correspondence with predefined polarization state vectors are disclosed. The described methods can be used cameras or image sensors measuring directly the polarization states of an incident electromagnetic waves. The devices include three-dimensional (3D) scattering structures made of dielectric pillars and using existing CMOS processes and direct write lithography techniques. Performance metrics based on the intensity and contrast of the split electromagnetic waves are also disclosed. |
| FILED | Tuesday, September 14, 2021 |
| APPL NO | 17/475167 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/283 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220004430 | Vega et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Augusto Vega (Mount Vernon, New York); Alper Buyuktosunoglu (White Plains, New York); Hubertus Franke (Cortlandt Manor, New York); John-David Wellman (Hopewell Junction, New York); Pradip Bose (Yorktown Heights, New York); Robert Matthew Senger (Tarrytown, New York); Aporva Amarnath (Ann Arbor, Michigan) |
| ABSTRACT | Described are techniques for scheduling tasks on a heterogeneous system on a chip (SoC). The techniques including receiving a directed acyclic graph at a meta pre-processor associated with a heterogeneous system-on-chip and communicatively coupled to a scheduler, where the directed acyclic graph corresponds to a control flow graph of respective tasks associated with an application executed by the heterogeneous system-on-chip. The techniques further including determining, using a learning agent implementing machine learning algorithms, a rank for a respective task in the directed acyclic graph, wherein the learning agent receives as input the directed acyclic graph, constraints associated with the directed acyclic graph, and heuristics regarding previously completed tasks. The techniques further including providing the respective task to the scheduler for execution on the heterogeneous system-on-chip according to the rank. |
| FILED | Wednesday, July 01, 2020 |
| APPL NO | 16/917981 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/4881 (20130101) Original (OR) Class G06F 16/9024 (20190101) Computer Systems Based on Specific Computational Models G06N 5/043 (20130101) G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220004433 | Vega et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Augusto Vega (Mount Vernon, New York); Alper Buyuktosunoglu (White Plains, New York); Hubertus Franke (Cortlandt Manor, New York); John-David Wellman (Hopewell Junction, New York); Pradip Bose (Yorktown Heights, New York); Robert Matthew Senger (Tarrytown, New York); Aporva Amarnath (Ann Arbor, Michigan) |
| ABSTRACT | Described are techniques for scheduling tasks on a heterogeneous system on a chip (SoC). The techniques including receiving a directed acyclic graph at a meta pre-processor associated with a heterogeneous SoC and communicatively coupled to a scheduler, wherein the directed acyclic graph corresponds to a control flow graph of tasks associated with an application executed by the heterogeneous SoC. The techniques further including determining a rank for a respective task in the directed acyclic graph, wherein the rank is based on a priority of the respective task and a slack in the directed acyclic graph. The techniques further including providing the respective task to the scheduler for execution on the heterogeneous SoC according to the rank. |
| FILED | Wednesday, July 01, 2020 |
| APPL NO | 16/917975 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/4893 (20130101) Original (OR) Class G06F 16/9024 (20190101) G06F 2209/486 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 20/145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220004709 | WU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTH CAROLINA STATE UNIVERSITY (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tianfu WU (Cary, North Carolina); Xilai LI (Raleigh, North Carolina) |
| ABSTRACT | The exemplified methods and systems provides deep neural network configured with a deep compositional grammatical architecture (e.g., to facilitate end-to-end representation learning). The instant deep compositional grammatical architecture beneficially integrates the compositionality and reconfigurability of grammar models with the capability of learning rich features of the deep neural networks in a principled way (e.g., for a convolutional neural network or a recombinant neural network). The instant deep compositional grammatical architecture utilizes AND-OR grammars to form an AND-OR grammar network. |
| FILED | Thursday, November 14, 2019 |
| APPL NO | 17/293980 |
| CURRENT CPC | Electric Digital Data Processing G06F 16/9024 (20190101) G06F 40/253 (20200101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/628 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220005367 | Gera et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ralucca Gera (Seaside, California); Michelle Lynn Isenhour (Pinehurst, North Carolina); D'Marie Ellison Bartolf (Owings, Maryland) |
| ABSTRACT | An adaptive education system is described. The adaptive education system includes a storage device to store aggregated learning content that includes learning units with learning material, the learning material having audio material, visual material, audiovisual material, or interactive material, CHUNKlets that each is of a CHUNKlet type and includes learning units, where the CHUNKlet type is an introductory type, an assessment type, an application type, or a methodology type, and CHUNKs that each includes CHUNKlets. The adaptive education system also includes an aggregation engine to group learning units into CHUNKlets and CHUNKlets into CHUNKs based on inputs from course authors and define prerequisite relationships between CHUNKs based on inputs from course authors. |
| FILED | Tuesday, July 06, 2021 |
| APPL NO | 17/368639 |
| CURRENT CPC | Electric Digital Data Processing G06F 16/435 (20190101) G06F 16/438 (20190101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 5/12 (20130101) G09B 5/067 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220005516 | Victora et al. |
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| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Randall H. Victora (New Brighton, Minnesota); Roy C. Bell (Minneapolis, Minnesota) |
| ABSTRACT | An example article includes a composite free layer and a conductive channel. The composite free layer includes a high-anisotropy ferromagnetic layer, a non-magnetic transition metal layer adjacent to the high anisotropy ferromagnetic layer, and an ultra-low damping magnetic insulator. The non-magnetic transition metal layer is between the ultra-low damping magnetic insulator and the high-anisotropy ferromagnetic layer. An example spin-orbit torque (SOT) stack may include the example article. Techniques for forming and switching example articles and SOT stacks are described. |
| FILED | Friday, September 10, 2021 |
| APPL NO | 17/447354 |
| CURRENT CPC | Static Stores G11C 11/161 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/222 (20130101) H01L 43/08 (20130101) H01L 43/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220005707 | Aliev et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ali E. Aliev (Plano, Texas); Ray H. Baughman (Dallas, Texas) |
| ABSTRACT | A dry-state non-contact method for patterning of nanostructured conducting materials is disclosed. Short self-generated electron-emission pulses in air at atmospheric pressure can enable an electron-emission-based (field enhancement) interaction between a sharp tungsten tip and elements of the nanostructured materials to cause largely non-oxidative sequential decomposition of the nanostructured elements. Embodiments can employ a substrate/tip gap of 10 to 20 nm, discharge voltages of 25-30 V, and patterning speeds as fast as 10 cm/s to provide precisely patterned nanostructures (<200 nm) that are largely free of foreign contaminants, thermal impact and sub-surface structural changes. |
| FILED | Friday, July 02, 2021 |
| APPL NO | 17/305295 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/32136 (20130101) Original (OR) Class H01L 51/0018 (20130101) H01L 51/0048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220005980 | Margalith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Tal Margalith (Santa Barbara, California); Matthew S. Wong (Santa Barbara, California); Lesley Chan (Goleta, California); Steven P. DenBaars (Goleta, California) |
| ABSTRACT | Micro-scale light emitting diodes (micro-LEDs) with ultra-low leakage current results from a sidewall passivation method for the micro-LEDs using a chemical treatment followed by conformal dielectric deposition, which reduces or eliminates sidewall damage and surface recombination, and the passivated micro-LEDs can achieve higher efficiency than micro-LEDs without sidewall treatments. Moreover, the sidewall profile of micro-LEDs can be altered by varying the conditions of chemical treatment. |
| FILED | Thursday, October 31, 2019 |
| APPL NO | 17/281700 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/30621 (20130101) H01L 33/007 (20130101) H01L 33/025 (20130101) H01L 33/32 (20130101) H01L 33/44 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220006005 | Sun et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nian-Xiang Sun (Winchester, Massachusetts); Nirjhar Bhattacharjee (Cambridge, Massachusetts) |
| ABSTRACT | A sputter growth method for a crystalline ordered topological insulator (TI) material on an amorphous substrate, which is possible to use at a CMOS-compatible temperature. The process can be integrated into CMOS fabrication processes for Spin Orbit Torque (SOT) devices. The resulting material can include a thin film crystalline ordered TI layer, sputter deposited on an amorphous substrate, and an adjacent ferromagnetic (FM) layer in which spin-orbit torque is provided by the TI layer, for example to cause switching in magnetic states in a magnetic memory device. |
| FILED | Thursday, July 01, 2021 |
| APPL NO | 17/365779 |
| CURRENT CPC | Static Stores G11C 11/161 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/222 (20130101) H01L 43/02 (20130101) H01L 43/08 (20130101) Original (OR) Class H01L 43/10 (20130101) H01L 43/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220006027 | Forrest et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen R. Forrest (Ann Arbor, Michigan); Jongchan Kim (Ann Arbor, Michigan); Siwei Zhang (Ann Arbor, Michigan) |
| ABSTRACT | An organic light emitting device comprises an anode and a cathode, at least one organic layer configured between the anode and the cathode, and at least one two-dimensional emissive layer configured between the anode and the cathode. A method of fabricating an organic light emitting device is also disclosed. |
| FILED | Thursday, June 24, 2021 |
| APPL NO | 17/357485 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0059 (20130101) H01L 51/0067 (20130101) H01L 51/0072 (20130101) Original (OR) Class H01L 51/0073 (20130101) H01L 51/0074 (20130101) H01L 51/5072 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220006104 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Zhongyang Wang (St. Louis, Missouri); Javier Parrondo (St. Louis, Missouri); Vijay K. Ramani (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Zhongyang Wang (St. Louis, Missouri); Javier Parrondo (St. Louis, Missouri); Vijay K. Ramani (St. Louis, Missouri) |
| ABSTRACT | The present disclosure is directed to triblock copolymer based anion exchange membranes (AEMs) and methods for making same. The membranes are useful as separators in electrochemical devices, such as fuel cells, electrolyzers, water desalination systems, and redox flow batteries. |
| FILED | Monday, December 07, 2020 |
| APPL NO | 17/113973 |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/2243 (20130101) C08J 2353/00 (20130101) C08J 2353/02 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/368 (20130101) H01M 8/188 (20130101) H01M 8/0221 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220007311 | Kwon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wichita State University (Wichita, Kansas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hyuck M. Kwon (Wichita, Kansas); Madhuprana Goswami (Wichita, Kansas); Vidhi Rana (Wichita, Kansas); Khanh Pham (Albuquerque, New Mexico) |
| ABSTRACT | A satellite communications system is disclosed, the system comprising a ground controller, a decode-and-forward (DF) satellite transponder, and a digital high-power amplifier (HPA). The DF is further comprised of a transponder front end including a digital channelizer and a predistorter. The ground controller is configured to transmit multiple-access frequency-division-multiplexed signals to the DF, where the DF is configured to down-convert the signals received at the transponder front end. The digital channelizer is configured to convert the signals received into a single sample steam and feed the stream through the predistorter into the single digital HPA, wherein the HPA is configured to amplify each input sample of the stream in sample-by-sample fashion and generates a discrete output. The DF is further configured to convert the output of the digital HPA to a continuous time signal and up-convert the output with a main carrier frequency for down-link transmission to multiple-access ground users. |
| FILED | Tuesday, June 29, 2021 |
| APPL NO | 17/361962 |
| CURRENT CPC | Transmission H04B 1/59 (20130101) H04B 7/19 (20130101) H04B 7/2621 (20130101) H04B 7/18517 (20130101) Wireless Communication Networks H04W 52/52 (20130101) Original (OR) Class H04W 52/243 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20220000912 | Morrison et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Keith David Morrison (Livermore, California); Gabriela G. Loots (Oakland, California); Ty James Samo (Walnut Creek, California); Kelly Anne Martin (Dublin, California) |
| ABSTRACT | Provided herein are pharmaceutical compositions comprising a Fe2+-exchanged fluorinated synthetic smectite and a synthetic semiconducting metal sulfide. The compositions can be used to treat topical conditions and gastrointestinal ailments, and can be incorporated into wound dressings, hydrogels, personal protective equipment, and 3D printed articles. Also provided are methods of synthesizing the Fe2+-exchanged fluorinated synthetic smectite and methods of making the synthetic semiconducting metal sulfide. |
| FILED | Friday, June 25, 2021 |
| APPL NO | 17/358929 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/26 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/18 (20130101) A61L 15/44 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 70/10 (20200101) B33Y 80/00 (20141201) Compositions of Macromolecular Compounds C08L 83/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001347 | YE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Congwang YE (Livermore, California); Julie A. MANCINI (Livermore, California); Kevin Scott PAULSEN (Oakland, California); William SMITH (Oakland, California) |
| ABSTRACT | The present disclosure relates to a nozzle system for use in a microfluidic production application for producing at least one of particles, capsules or fibers. The system has a main body portion having a compressed fluid inlet and a core fluid inlet, and a plurality of parallel arranged core fluid nozzles that receive the core fluid and create a plurality of core fluid streams. At least one compressed fluid inlet associated with the main body channels compressed fluid to areas adjacent ends of the core fluid nozzles. An apertured plate having a plurality of apertures is arranged near the ends of the core fluid nozzles, with each aperture being uniquely associated with a single one of the core fluid nozzles. The compressed fluid acts on the core fluid streams exiting the core fluid nozzles to help create, with the apertures, at least one of core fluid droplets or core fluid fibers from the core fluid streams. |
| FILED | Thursday, July 02, 2020 |
| APPL NO | 16/920083 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 2/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001352 | Leon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Patricia Ignacio de Leon (Westmont, Illinois); Philip D. Laible (Downers Grove, Illinois); Mackenzie Elizabeth Meyer (Ann Arbor, Michigan); Christopher R. Povinelli (Milwaukee, Wisconsin); Killian L. Tracey (Geneva, Illinois); Daniel Yoav Arenas (Chicago, Illinois) |
| ABSTRACT | A process for separations and recovery from mixtures via specific adsorption using high-surface area, flexible silica-based nanostructured gel adsorbents and articles of manufacture relating to same. |
| FILED | Friday, July 02, 2021 |
| APPL NO | 17/367205 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/24 (20130101) B01J 20/103 (20130101) Original (OR) Class B01J 20/223 (20130101) B01J 20/3064 (20130101) B01J 20/3085 (20130101) B01J 20/3204 (20130101) B01J 20/3265 (20130101) B01J 20/3268 (20130101) B01J 20/28047 (20130101) B01J 20/28085 (20130101) Non-metallic Elements; Compounds Thereof; C01B 33/163 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 3/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001357 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Sumin Lee (Berkeley, California); Adam Uliana (Berkeley, California); Jeffrey R. Long (Berkeley, California); Christopher J. Chang (Berkeley, California) |
| ABSTRACT | Ether-thioether functionalized porous aromatic framework (PAF) polymers provide high selectivity for iron(II) and iron(III) adsorption in aqueous samples. |
| FILED | Friday, September 17, 2021 |
| APPL NO | 17/478874 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/265 (20130101) Original (OR) Class B01J 20/3085 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/285 (20130101) C02F 2101/203 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 31/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001530 | SAMEOTO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dan SAMEOTO (Edmonton, Canada); Amit NAGARKAR (Boston, Massachusetts); Daniel J. PRESTON (Cambridge, Massachusetts); Stephanie OYOLA-REYNOSO (Burlington, Massachusetts); George M. WHITESIDES (Newton, Massachusetts) |
| ABSTRACT | An actuator is described, including a first sheet comprising a plurality of first openings,; and a second sheet comprising a plurality of second openings; wherein the first and second sheets are stacked together such that at least one of the first and second openings are misaligned; and the actuator is configured to move from a first state to a second state, wherein in the first state, out-of-plane motion of the first and second sheets is permitted; and in the second state, the first and second sheets as well as the misaligned first and second openings are jammed together to restrict the out-of-plane motion of the first and second sheets. Methods of actuating and making such actuator are also described. |
| FILED | Tuesday, October 29, 2019 |
| APPL NO | 17/289924 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1075 (20130101) Original (OR) Class Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 1/08 (20130101) B32B 3/263 (20130101) B32B 3/266 (20130101) B32B 7/022 (20190101) B32B 2307/732 (20130101) Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 15/103 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001850 | Ramakrishnan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cummins Inc. (Columbus, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kesavan Ramakrishnan (Columbus, Indiana); Vaidehi Y. Hoshing (Columbus, Indiana) |
| ABSTRACT | Methods and systems of power management in a hybrid vehicle are disclosed. A control system of the hybrid vehicle obtains battery temperature and catalyst temperature. The control system determines (a) whether the battery temperature is within an optimal battery temperature range and (b) whether the catalyst temperature is within an optimal catalyst temperature range. The control system determines a power split ratio (PSR) based on the determination of (a) and (b). The control system controls the engine and the motor-generator based on the determined PSR. |
| FILED | Wednesday, July 01, 2020 |
| APPL NO | 16/918481 |
| CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 10/06 (20130101) B60W 10/08 (20130101) B60W 20/16 (20160101) Original (OR) Class B60W 2510/244 (20130101) B60W 2510/246 (20130101) Gas-flow Silencers or Exhaust Apparatus for Machines or Engines in General; Gas-flow Silencers or Exhaust Apparatus for Internal Combustion Engines F01N 11/002 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/3461 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002229 | Jansone-Popova et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Santa Jansone-Popova (Knoxville, Tennessee); Ilja Popovs (Knoxville, Tennessee); Bruce A. Moyer (Oak Ridge, Tennessee) |
| ABSTRACT | Rare earth extractant compounds having the following structure: wherein R1, R2, R3, and R4 are independently selected from alkyl groups containing 1-30 carbon atoms and optionally containing an ether or thioether linkage connecting between carbon atoms, provided that the total carbon atoms in R1, R2, R3, and R4 is at least 12; R5 and R6 are independently selected from hydrogen atom and alkyl groups containing 1-3 carbon atoms; and provided that at least one of the conditions (i)-(iv) apply as follows: presence of a distal branched group in at least one of R1-R4 (condition i), asymmetry in R1-R4 (condition ii), presence of amine-containing ring (condition iii), or presence of lactam ring (condition iv). Also described are hydrophobic water-insoluble solutions containing at least one extractant compound of Formula (1), as well as method for extracting rare earth elements from aqueous solution by contacting the aqueous solution with the water-insoluble solution. |
| FILED | Friday, July 02, 2021 |
| APPL NO | 17/366172 |
| CURRENT CPC | Separation B01D 11/0492 (20130101) Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 17/17 (20200101) Acyclic or Carbocyclic Compounds C07C 235/06 (20130101) Original (OR) Class Heterocyclic Compounds C07D 207/08 (20130101) C07D 207/12 (20130101) C07D 211/42 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 3/282 (20210501) C22B 59/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002472 | Abu-Omar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Mahdi M. Abu-Omar (Goleta, California); Shou Zhao (Goleta, California) |
| ABSTRACT | A thermoset precursor composition includes a backbone comprising an imine bond bonding at least one of: 1) aromatic compounds together, or 2) bonding an aromatic compound to an aliphatic chain, and at least one of: an epoxy group terminating the backbone or an aldehyde group terminating the backbone. The thermoset precursor can have at least two epoxy groups, one epoxy group and one aldehyde group, or two aldehyde groups. |
| FILED | Wednesday, November 20, 2019 |
| APPL NO | 17/294244 |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 59/28 (20130101) C08G 59/3227 (20130101) Original (OR) Class Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 11/08 (20130101) C08J 2363/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002555 | MELOSH et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicholas Alexander MELOSH (Menlo Park, California); Matthew A. GEBBIE (Stanford, California); Patrick MCQUADE (Stanford, California); Andrew E. GONZALEZ (Stanford, California) |
| ABSTRACT | This disclosure enables the generation and patterning of color centers with nanometer-scale spatial control in a variety of materials in repeatable fashion and without the use of radiation. Embodiments in accordance with the present disclosure employ a layer of vacancy-injection material disposed on a host-material, where the vacancy-injection material forms a compound with host-material atoms at elevated temperatures. During compound formation, lattice vacancies are generated in the host material and diffuse within the substrate lattice to bond with impurity atoms, thereby forming color centers. High-resolution lithographic patterning of the vacancy-injection film and the short diffusion lengths of the lattice vacancies enables nanometer-level spatial control over the lateral positions of the color centers. Furthermore, the depth of the color centers in the substrate can be controlled by controlling the coating material, thickness, anneal time, and anneal temperature. |
| FILED | Wednesday, October 30, 2019 |
| APPL NO | 17/291494 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black; C09C 1/44 (20130101) Original (OR) Class C09C 3/04 (20130101) C09C 3/063 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/12 (20130101) C23C 16/56 (20130101) C23C 16/4417 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002619 | LUTHER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph Matthew LUTHER (Boulder, Colorado); Matthew Craig BEARD (Arvada, Colorado); Young-Hoon KIM (Lakewood, Colorado) |
| ABSTRACT | The present disclosure relates to a composition that includes a nanocrystalline core that includes a perovskite and having an outer surface, and a chiral molecule having a functional group, where the functional group is bonded to a first portion of the outer surface, and the composition is capable of circularly polarized luminescence (CPL). In some embodiments of the present disclosure, the composition is capable of absorbing circularly-polarized light. |
| FILED | Monday, June 28, 2021 |
| APPL NO | 17/360064 |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/24 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) Original (OR) Class C09K 2211/188 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 10/3259 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/02 (20130101) H01L 51/0077 (20130101) H01L 51/428 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002744 | Karlen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin); THE UNIVERSITY OF BRITISH COLUMBIA (Vancouver, Canada) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin); THE UNIVERSITY OF BRITISH COLUMBIA (Vancouver, Canada) |
| INVENTOR(S) | Steven D. Karlen (Madison, Wisconsin); Rebecca Anne Smith (Madison, Wisconsin); John Ralph (Madison, Wisconsin); Emily Beebe (Stoughton, Wisconsin); Craig Bingman (Fitchburg, Wisconsin); Brian Fox (Madison, Wisconsin); Shawn Mansfield (Vancouver, Canada); Heather Mackay (Vancouver, Canada); Hoon Kim (Madison, Wisconsin); Yaseen Mottiar (Vancouver, Canada); Faride Unda (Vancouver, Canada) |
| ABSTRACT | The invention is directed to BAHD acyltransferase enzymes, nucleic acids encoding BAHD acyltransferase enzymes, and inhibitory nucleic acids adapted to inhibit the expression and/or translation of BAHD acyltransferase RNA; expression cassettes, plant cells, and plants that have or encode such nucleic acids and enzymes; and methods of making and using such nucleic acids, enzymes, expression cassettes, cells, and plants. |
| FILED | Friday, November 08, 2019 |
| APPL NO | 17/291932 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1029 (20130101) C12N 15/8255 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002840 | Jansone-Popova et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Santa Jansone-Popova (Knoxville, Tennessee); Kevin L. Lyon (Rigby, Idaho); Ilja Popovs (Knoxville, Tennessee); Bruce A. Moyer (Oak Ridge, Tennessee) |
| ABSTRACT | A method for extracting rare earth elements from aqueous solution, comprising: (i) acidifying an aqueous solution containing said rare earth elements with an inorganic acid to result in an acidified aqueous solution containing said rare earth elements and containing the inorganic acid in a concentration of 1-12 M, wherein said rare earth elements are selected from lanthanides, actinides, or combination thereof, and (ii) contacting the acidified aqueous solution with an aqueous-insoluble hydrophobic solution comprising a rare earth extractant compound dissolved in an aqueous-insoluble hydrophobic solvent to result in extraction of one or more of the rare earth elements into the aqueous-insoluble hydrophobic solution by binding of the rare earth extractant compound to the one or more rare earth elements, wherein the rare earth extractant compound has the following structure: provided that at least one of the conditions (a)-(d) applies. |
| FILED | Friday, July 02, 2021 |
| APPL NO | 17/366185 |
| CURRENT CPC | Production and Refining of Metals; Pretreatment of Raw Materials C22B 7/007 (20130101) C22B 59/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002842 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Xinghang Zhang (West Lafayette, Indiana); Qiang Li (West Lafayette, Indiana); Haiyan Wang (West Lafayette, Indiana); Sichuang Xue (West Lafayette, Indiana); Yifan Zhang (West Lafayette, Indiana) |
| ABSTRACT | A high-strength aluminum alloy coating. The coating includes aluminum, 9R phase, fine grains, nanotwins, stacking faults, and a solute capable of stabilizing the 9R phase, the fine grains, and the stacking faults. A method of making a high-strength aluminum alloy coating on a substrate. The method includes, depositing the constituents of an aluminum alloy on a substrate such that the deposit forms a high-strength aluminum alloy coating containing 9R phase, fine grains, nanotwins, and stacking faults. A high-strength deformation layer in and on a casting of an aluminum alloy containing 9R phase, fine grains, nanotwins, stacking faults, and a solute capable of stabilizing the PR phase, the fine grains, and the stacking faults. A method of making a high-strength deformation layer in and on a casting of an aluminum alloy by deforming the alloy such that deformation layer contains 9R phase, fine grains, nanotwins, and stacking faults. |
| FILED | Friday, June 25, 2021 |
| APPL NO | 17/358844 |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 15/016 (20130101) B32B 2307/536 (20130101) Alloys C22C 21/00 (20130101) Original (OR) Class Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/04 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/12764 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002961 | Cotrell |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RCAM Technologies, Inc. (Boulder, Colorado) |
| ASSIGNEE(S) | RCAM Technologies, Inc. (Boulder, Colorado) |
| INVENTOR(S) | Jason Rust Cotrell (Boulder, Colorado) |
| ABSTRACT | In a general aspect, suction anchors are presented for securing structures to an underwater floor. The suction anchors include a tubular body formed at least in part of cementitious materials and having a closed end and an open end. The tubular body includes an edge defining an opening for the open end. The edge is configured to penetrate the underwater floor. The suction anchors also include a port configured to fluidly-couple a cavity within the tubular body to an exterior of the tubular body. The suction anchors additionally include a pad eye extending from an outer surface of the tubular body and configured to couple to a mooring line. In another aspect, methods of manufacturing the suction anchors are also presented. |
| FILED | Tuesday, August 03, 2021 |
| APPL NO | 17/392662 |
| CURRENT CPC | Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 1/001 (20130101) B28B 23/02 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Hydraulic Engineering E02B 2017/0078 (20130101) Foundations; Excavations; Embankments; Underground or Underwater Structures E02D 5/32 (20130101) Original (OR) Class E02D 27/525 (20130101) E02D 2250/0023 (20130101) Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 47/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002962 | Zeng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xiangwu Zeng (Solon, Ohio); Xuefei Wang (Cleveland Heights, Ohio); Xu Yang (Tianjin, China PRC); Xinyao Li (Cleveland, Ohio) |
| ABSTRACT | A hybrid offshore wind turbine includes a monopile, friction wheel, and suction bucket. |
| FILED | Monday, October 07, 2019 |
| APPL NO | 17/282890 |
| CURRENT CPC | Foundations; Excavations; Embankments; Underground or Underwater Structures E02D 27/425 (20130101) Original (OR) Class E02D 27/525 (20130101) Wind Motors F03D 13/22 (20160501) F03D 13/25 (20160501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220003353 | Gorodetsky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Alon A. Gorodetsky (Irvine, California); Steven R. Jim (Hillsboro, Oregon); George Stiubianu (Iasi, Romania); Erica Leung (Piedmont, California); Kyle Naughton (Laguna Beach, California); Priyam Patel (Irvine, California); Maurizio Follador (Givoletto, Italy); Emil Karshalev (San Diego, California) |
| ABSTRACT | Composite materials with adjustable spectral properties comprised of IR-reflecting micro-domains overlaying an IR-transparent elastomeric matrix, and capable of dynamically controlling IR radiation transmission are described, as well as methods of fabrication thereof. Systems with capabilities to regulate IR radiation (including heat) transmission based thereon, and methods of regulating IR radiation transmission (including thermal regulation) using the same are also provided. |
| FILED | Wednesday, November 27, 2019 |
| APPL NO | 17/297888 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 41/003 (20130101) B29C 41/04 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2025/08 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/0005 (20130101) C23C 14/16 (20130101) C23C 14/30 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 59/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220003503 | IYER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jaisree Kannan IYER (Fremont, California); Pratanu ROY (San Ramon, California); Du T. NGUYEN (Fremont, California); Joshuah K. STOLAROFF (Oakland, California) |
| ABSTRACT | The present disclosure relates to a transport mechanism apparatus for transporting at least one of a gas or a fluid. The transport mechanism may have an inlet, an outlet and an engineered cellular structure forming a periodic nodal surface, which may include a triply periodic minimal surface (TPMS) structure. The structure is formed in a layer-by-layer three dimensional (3D) printing operation to include cells propagating in three dimensions, where the cells include non-intersecting, continuously curving wall portions having openings, and where the opening in the cells form a plurality of flow paths throughout the transport mechanism from the inlet to the outlet, and where portions of the cells form the inlet and the outlet. |
| FILED | Thursday, July 01, 2021 |
| APPL NO | 17/365622 |
| CURRENT CPC | Separation B01D 53/0407 (20130101) B01D 67/002 (20130101) B01D 67/0041 (20130101) B01D 69/02 (20130101) Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/04099 (20130101) B01F 5/0691 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 4/004 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Come into Direct Contact Without Chemical Interaction F28C 3/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220003628 | Challener |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William Albert Challener (Glenville, New York) |
| ASSIGNEE(S) | BAKER HUGHES HOLDINGS LLC (Houston, Texas) |
| INVENTOR(S) | William Albert Challener (Glenville, New York) |
| ABSTRACT | A gas sensing tube includes an outer surface, and an inner surface defining a passage. A sensor node is arranged along the sensing tube. The sensor node includes an inlet fluidically connected to the passage, an outlet fluidically connected to the passage, and an interior chamber arranged between the inlet and the outlet. A sensor cable extends along the sensing tube. The sensor cable includes a first conduit having a first connector coupled to the sensor node at the inlet and a second conduit having a second connector connected to the sensor node at the outlet. The sensor cable has a first conductor extending through the first conduit and being coupled to the first connector and a second conductor extending through the second conduit and being coupled to the second connector. |
| FILED | Thursday, September 16, 2021 |
| APPL NO | 17/476688 |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 3/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220003694 | SEIDLER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gerald Todd SEIDLER (Seattle, Washington); Oliver HOIDN (Seattle, Washington); William HOLDEN (Seattle, Washington) |
| ABSTRACT | A spectrometer includes a crystal analyzer having a radius of curvature that defines a Rowland circle, a sample stage configured to support a sample such that the sample is offset from the Rowland circle, x-ray source configured to emit unfocused x-rays toward the sample stage, and a position-sensitive detector that is tangent to the Rowland circle. A method performed via a spectrometer includes emitting, via an x-ray source, unfocused x-rays toward a sample that is mounted on a sample stage such that the sample is offset from the Rowland Circle, thereby causing the sample to emit x-rays that impinge on the crystal analyzer or transmit a portion of the unfocused x-rays to impinge on the crystal analyzer; scattering, via the crystal analyzer, the x-rays that impinge on the crystal analyzer; and detecting the scattered x-rays via a position-sensitive detector that is tangent to the Rowland circle. |
| FILED | Friday, July 02, 2021 |
| APPL NO | 17/366759 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/207 (20130101) G01N 23/2076 (20130101) Original (OR) Class G01N 23/20008 (20130101) G01N 23/20025 (20130101) G01N 23/20091 (20130101) G01N 2223/5015 (20130101) Measurement of Nuclear or X-radiation G01T 7/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220003773 | Winter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jessica Winter (Columbus, Ohio); Elizabeth Jergens (Columbus, Ohio); Kil Ho Lee (Columbus, Ohio) |
| ABSTRACT | Disclosed herein are erasable label systems that involve nanocage molecules positioned around nanoparticles, which can be loaded with, bound to, or adsorbed with imaging agents. The nanocages can contain targeting arms composed of ssDNA or ssRNA that can be used to target biomolecules. For DNA or RNA targeting, this can be done directly. Antibodies can be targeted using avidin-biotin coupling to ssDNA or direct ssDNA conjugation to the antibody surface. ssDNA or ssRNA complementary to one of the arms can then be used to “erase” the label. |
| FILED | Friday, November 15, 2019 |
| APPL NO | 17/292955 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/585 (20130101) Original (OR) Class G01N 33/54393 (20130101) G01N 2458/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220003826 | Ohodnicki et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States Department of Energy (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul Ohodnicki (Pittsburgh, Pennsylvania); Derek Lau (San Jose, California); Jagannath Devkota (Pittsburgh, Pennsylvania); Michael McHenry (Pittsburgh, Pennsylvania); Alex Leary (Pittsburgh, Pennsylvania); Richard Beddingfield (Raleigh, North Carolina); Michael Buric (Morgantown, West Virginia) |
| ABSTRACT | The invention provides a method for measuring the magnetic field of an electromagnetic component having the steps of: instrumenting one or more portions of an electromagnetic component by placing an optical fiber in electromagnetic communication with the one or more portions of said electromagnetic component; energizing the electromagnetic component; interrogating the optical fiber using light and an optical detector; and determining changes in the magnetic field incident on the optical fiber based on the detected changes in the light received by the optical detector. |
| FILED | Monday, July 19, 2021 |
| APPL NO | 17/379389 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/032 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220003884 | GARZON et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNM Rainforest Innovations (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Fernando Henry GARZON (Santa Fe, New Mexico); Kannan RAMAIYAN (Albuquerque, New Mexico); Kyle TROCHE (Albuquerque, New Mexico); Timothy J. Boyle (Albuquerque, New Mexico) |
| ABSTRACT | A low cost, rapid, flexible radiation detector uses inorganic metal halide precursors and dyes that respond to self-quenching hybrid scintillation. Remote, high-contrast, laser sensing can be used to determine when exposure of the detector to radiation occurs (even temporally). |
| FILED | Wednesday, July 21, 2021 |
| APPL NO | 17/382140 |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 29/12 (20130101) Measurement of Nuclear or X-radiation G01T 1/2023 (20130101) G01T 1/2045 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220004425 | Baskaran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Reservoir Labs, Inc. (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Muthu M. Baskaran (Old Tappan, New Jersey); Thomas Henretty (Brooklyn, New York); M. H. Langston (Beacon, New York); Richard A. Lethin (New York, New York); Benoit J. Meister (New York, New York); Nicolas T. Vasilache (New York, New York); David E. Wohlford (Portland, Oregon) |
| ABSTRACT | In a system for automatic generation of event-driven, tuple-space based programs from a sequential specification, a hierarchical mapping solution can target different runtimes relying on event-driven tasks (EDTs). The solution uses loop types to encode short, transitive relations among EDTs that can be evaluated efficiently at runtime. Specifically, permutable loops translate immediately into conservative point-to-point synchronizations of distance one. A runtime-agnostic which can be used to target the transformed code to different runtimes. |
| FILED | Friday, February 14, 2020 |
| APPL NO | 16/791361 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/4843 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220005625 | EHST et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | David A. EHST (Downers Grove, Illinois); James L. WILLIT (Batavia, Illinois) |
| ABSTRACT | The present invention provides a target unit and a sublimation apparatus suitable for use in a method for producing Cu67 radioisotope suitable for use in medical applications. The apparatus comprises a sublimation tube with one open end. The sublimation tube contains an ingot comprising Zn68 and Cu67 in a ceramic capsule contacting a closed end the sublimation tube. A removable vacuum dome is sealable over the open end of the sublimation tube so that interior of the apparatus can be placed under vacuum. |
| FILED | Wednesday, June 23, 2021 |
| APPL NO | 17/355679 |
| CURRENT CPC | Separation B01D 7/00 (20130101) Conversion of Chemical Elements; Radioactive Sources G21G 1/001 (20130101) G21G 1/12 (20130101) G21G 2001/0094 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 5/08 (20130101) Original (OR) Class Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 6/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220005651 | Campbell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Patrick G. Campbell (Livermore, California); Monika M. Biener (Livermore, California); Maira Raquel Ceron Hernandez (Livermore, California) |
| ABSTRACT | Disclosed here is a method for producing a graphene macro-assembly (GMA)-fullerene composite, comprising providing a mixture of graphene oxide and water, adding a hydroxylated fullerene to the mixture, and forming a gel of the hydroxylated fullerene and the mixture. Also described are a GMA-fullerene composite produced, an electrode comprising the GMA-fullerene composite, and a supercapacitor comprising the electrode. |
| FILED | Friday, July 02, 2021 |
| APPL NO | 17/367167 |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/64 (20130101) C04B 35/528 (20130101) C04B 35/624 (20130101) C04B 35/62635 (20130101) C04B 2235/422 (20130101) C04B 2235/528 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/34 (20130101) H01G 11/36 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220005998 | Lagally et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin); University of Hamburg (Hamburg, Germany) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Max G. Lagally (Madison, Wisconsin); Robert H. Blick (Hamburg, Germany) |
| ABSTRACT | Josephson junctions (JJ) based on bilayers of azimuthally misaligned two-dimensional materials having superconducting states are provided. Also provided are electronic devices and circuits incorporating the JJs as active components and methods of using the electronic devices and circuits. The JJs are formed from bilayers composed of azimuthally misaligned two-dimensional materials having a first superconducting segment and a second superconducting segment separated by a weak-link region that is integrated into the bilayer. |
| FILED | Friday, July 02, 2021 |
| APPL NO | 17/366195 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/025 (20130101) Original (OR) Class H01L 39/125 (20130101) H01L 39/223 (20130101) H01L 39/228 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 3/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220006090 | Hays et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Zenlabs Energy, Inc. (Fremont, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kevin Hays (Fremont, California); Subramanian Venkatachalam (Pleasanton, California); Herman A. Lopez (Sunnyvale, California) |
| ABSTRACT | Polymer binders for negative electrodes with silicon based active materials are described based on poly(acrylamide-co-acrylate salts). Lithium ion batteries incorporating electrodes formed with the binders achieve longer cycling with suitable performance. Mechanical properties associated with each of the moieties of the copolymers are studied to guide polymer selection. |
| FILED | Thursday, July 02, 2020 |
| APPL NO | 16/920047 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/48 (20130101) H01M 4/587 (20130101) H01M 4/622 (20130101) Original (OR) Class H01M 4/1315 (20130101) H01M 10/0525 (20130101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220006104 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Zhongyang Wang (St. Louis, Missouri); Javier Parrondo (St. Louis, Missouri); Vijay K. Ramani (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Zhongyang Wang (St. Louis, Missouri); Javier Parrondo (St. Louis, Missouri); Vijay K. Ramani (St. Louis, Missouri) |
| ABSTRACT | The present disclosure is directed to triblock copolymer based anion exchange membranes (AEMs) and methods for making same. The membranes are useful as separators in electrochemical devices, such as fuel cells, electrolyzers, water desalination systems, and redox flow batteries. |
| FILED | Monday, December 07, 2020 |
| APPL NO | 17/113973 |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/2243 (20130101) C08J 2353/00 (20130101) C08J 2353/02 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/368 (20130101) H01M 8/188 (20130101) H01M 8/0221 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220006196 | Byers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (KANSAS CITY, Missouri) |
| INVENTOR(S) | Kyle J. Byers (Kansas City, Missouri); Louis Brown (Kansas City, Missouri); Daniel John Salzman (Lees Summit, Missouri) |
| ABSTRACT | A method of tuning an electrically small antenna comprising a radiating element and a support structure comprises applying a force to the support structure to change a shape or a dimension of the radiating element to increase or decrease a frequency at which the electrically small antenna resonates. |
| FILED | Wednesday, July 01, 2020 |
| APPL NO | 16/918157 |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/36 (20130101) H01Q 9/14 (20130101) Original (OR) Class H01Q 9/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220006793 | Choi |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sung Nam Choi (Sandia Park, New Mexico) |
| ABSTRACT | The present disclosure is directed to methods that provide a secure communication protocol by utilizing one step process of authenticating and encrypting data without having to exchange symmetric keys or needing to renew or re-issue digital identities fundamental to asymmetric encryption methodology. |
| FILED | Thursday, July 08, 2021 |
| APPL NO | 17/370769 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0643 (20130101) H04L 9/0866 (20130101) H04L 9/0869 (20130101) H04L 9/3236 (20130101) H04L 63/06 (20130101) H04L 63/083 (20130101) H04L 63/0435 (20130101) Original (OR) Class H04L 63/0853 (20130101) H04L 2209/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20220000408 | EMAMINEJAD et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Sam EMAMINEJAD (Los Angeles, California); Shuyu LIN (Los Angeles, California) |
| ABSTRACT | Example implementations include a device with an electrode electrically responsive to presence of a biochemical present within a biofluid, and one or more biofouling and interferent mitigation layers disposed on the electrode to block transmission of biofouling agents to the electrode and the reaction of interferents on the electrode. Example implementations also include a method of obtaining a biofluid sample, mitigating a biofouling characteristic associated with the biofluid sample, and obtaining a biochemical characteristic associated with the biofluid sample. |
| FILED | Tuesday, July 06, 2021 |
| APPL NO | 17/368694 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/256 (20210101) A61B 5/263 (20210101) Original (OR) Class A61B 5/4266 (20130101) A61B 5/4277 (20130101) A61B 2562/125 (20130101) A61B 2562/0209 (20130101) A61B 2562/247 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220000498 | Leuthardt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eric Leuthardt (St. Louis, Missouri); Mohamed Zayed (St. Louis, Missouri); Guy Genin (St. Louis, Missouri); Joshua Osbun (St. Louis, Missouri); Gayan De Silva (St. Louis, Missouri); Sanghun A. Lee (St. Louis, Missouri); Dillon Williams (St. Louis, Missouri); Alexander Wirtz (St. Louis, Missouri) |
| ABSTRACT | The disclosure provides for an adjustable catheter system with isovolumetric suction and restoration of fluid for the removal of a thrombus and a method of use thereof. The catheter system includes an inner catheter and an outer sheath surrounding at least a portion of the inner catheter. The inner catheter may include at least three lumina extending from the proximal end to the distal end of the inner catheter, at least one infusion fenestration along the infusion segment, and a distal encapsulation balloon at the distal end. The outer sheath may include at least three lumina extending from the proximal end to the distal end of the outer sheath and a proximal encapsulation balloon at the distal end. The catheter system may further include an agitator for mechanical morcellation of the thrombus. |
| FILED | Tuesday, September 07, 2021 |
| APPL NO | 17/467926 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/22 (20130101) Original (OR) Class A61B 17/320725 (20130101) A61B 2017/22054 (20130101) A61B 2017/22062 (20130101) A61B 2017/22079 (20130101) A61B 2017/22082 (20130101) A61B 2017/320012 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/003 (20130101) A61M 25/0043 (20130101) A61M 25/0662 (20130101) A61M 25/1011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220000768 | Freeman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (, None) |
| INVENTOR(S) | William Freeman (Del Mar, California); Michael J. Sailor (La Jolla, California); Lingyun Cheng (San Diego, California); Frederique Cunin (Montpellier, France); Emily Anglin (San Diego, California); Yang Yang Li (Hong Kong, China Hong Kong) |
| ABSTRACT | A minimally invasive controlled drug delivery system for delivering a particular drug or drugs to a particular location of the eye, the system including a porous film template having pores configured and dimensioned to at least partially receive at least one drug therein, and wherein the template is dimensioned to be delivered into or onto the eye. |
| FILED | Monday, November 06, 2017 |
| APPL NO | 15/804856 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/0017 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) Original (OR) Class A61K 9/0051 (20130101) A61K 47/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220000799 | DONG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| ASSIGNEE(S) | THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| INVENTOR(S) | Jiajia DONG (Shanghai city, China PRC); K. Barry SHARPLESS (La Jolla, California); Jeffery W. KELLY (La Jolla, California); Aleksandra BARANCZAK (Gurnee, Illinois); Wentao CHEN (Walnut Creek, California) |
| ABSTRACT | This application describes modified amino acids and polypeptides comprising a SO2F or CH2CH2SO2F group bound to the side chain of an amono acid or amino acid residue of a polypeptide in place of a hydrogen of a hydroxyl or amino substituent thereof. Methods of covalently binding the polypeptides to receptot sites of receptor proteins are also described herein. |
| FILED | Friday, September 10, 2021 |
| APPL NO | 17/471936 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/05 (20130101) Original (OR) Class A61K 31/14 (20130101) A61K 31/40 (20130101) A61K 31/47 (20130101) A61K 31/53 (20130101) A61K 31/56 (20130101) A61K 31/65 (20130101) A61K 31/70 (20130101) A61K 31/136 (20130101) A61K 31/197 (20130101) A61K 31/198 (20130101) A61K 31/397 (20130101) A61K 31/407 (20130101) A61K 31/439 (20130101) A61K 31/473 (20130101) A61K 31/485 (20130101) A61K 31/505 (20130101) A61K 31/515 (20130101) A61K 31/655 (20130101) A61K 31/4045 (20130101) A61K 31/4168 (20130101) A61K 31/4245 (20130101) A61K 31/4353 (20130101) A61K 31/4709 (20130101) A61K 31/4745 (20130101) A61K 31/5513 (20130101) A61K 31/7048 (20130101) A61K 38/31 (20130101) A61K 47/54 (20170801) A61K 51/0497 (20130101) Acyclic or Carbocyclic Compounds C07C 305/26 (20130101) C07C 2601/14 (20170501) C07C 2603/18 (20170501) Heterocyclic Compounds C07D 277/82 (20130101) C07D 279/08 (20130101) C07D 295/26 (20130101) C07D 295/088 (20130101) C07D 295/185 (20130101) C07D 501/18 (20130101) Peptides C07K 1/02 (20130101) C07K 1/1136 (20130101) C07K 2/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001048 | Jun et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Young-Shin Jun (St. Louis, Missouri); Srikanth Singamaneni (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Young-Shin Jun (St. Louis, Missouri); Srikanth Singamaneni (St. Louis, Missouri) |
| ABSTRACT | Self-sterilizing filtration materials are disclosed that include at least one polydopamine-functionalized layer. The at least one polydopamine-functionalized layer is configured to heat to a sterilization temperature when illuminated by light with a light intensity. The self-sterilizing filtration materials may be included in a filtering respirator mask. Methods of sterilizing filtration materials and filtering respirator masks containing at least one polydopamine-functionalized layer by exposing to sunlight are also disclosed. In addition, methods of producing a self-sterilizing filtering respirator mask by polydopamine-functionalizing at least one layer of the filtration material in an existing filtering respirator mask. |
| FILED | Friday, July 02, 2021 |
| APPL NO | 17/366440 |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 13/1192 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/084 (20130101) Original (OR) Class Devices, Apparatus or Methods for Life-saving A62B 23/025 (20130101) Separation B01D 39/083 (20130101) B01D 46/0001 (20130101) B01D 46/0028 (20130101) B01D 46/0063 (20130101) B01D 2239/10 (20130101) B01D 2239/0428 (20130101) B01D 2239/0442 (20130101) B01D 2239/0478 (20130101) B01D 2239/0618 (20130101) B01D 2239/0622 (20130101) B01D 2239/0627 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001077 | RUBERTI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeffrey William RUBERTI (Lexington, Massachusetts); Patrick Anthony BRADLEY (Boston, Massachusetts) |
| ABSTRACT | Compositions and methods are provided to accelerate and improve wound repair and reconstruction of connective tissue structures, including tendons, by assembly of collagen using liquid crystalline collagen. The compositions and methods can be used to treat various forms of connective tissue injury or to prevent or slow degeneration to vulnerable tendons that are generally refractory to repair. |
| FILED | Wednesday, November 13, 2019 |
| APPL NO | 17/293561 |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 23/0245 (20130101) A61H 2201/10 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/39 (20130101) A61K 38/1841 (20130101) A61K 38/2006 (20130101) A61K 38/4886 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/24 (20130101) Original (OR) Class A61L 27/54 (20130101) A61L 27/227 (20130101) A61L 27/386 (20130101) A61L 27/3834 (20130101) A61L 27/3843 (20130101) A61L 27/3895 (20130101) A61L 2300/41 (20130101) A61L 2300/236 (20130101) A61L 2300/252 (20130101) A61L 2300/412 (20130101) A61L 2400/12 (20130101) A61L 2430/10 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/04 (20180101) Peptides C07K 14/78 (20130101) Compositions of Macromolecular Compounds C08L 89/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001208 | Zeidell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WAKE FOREST UNIVERSITY (Winston-Salem, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew Zeidell (Winston-Salem, North Carolina); Oana D. Jurchescu (Winston-Salem, North Carolina); J. Daniel Bourland (Winston-Salem, North Carolina); Tong Ren (Winston-Salem, North Carolina) |
| ABSTRACT | In one aspect, radiation dosimeters are described herein comprising organic field effect transistors. Briefly, a radiation dosimeter comprises an organic field effect transistor having composition and/or electronic structure exhibiting a shift in threshold voltage as a function of radiation dose. |
| FILED | Thursday, July 01, 2021 |
| APPL NO | 17/365438 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1071 (20130101) Original (OR) Class Measurement of Nuclear or X-radiation G01T 1/026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001441 | Han |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Qingyou Han (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Qingyou Han (West Lafayette, Indiana) |
| ABSTRACT | A method of forming high quality metallurgical bonds in a composite casting is provided. The bonding technology of this invention includes the step of introducing a liquid material to contact the solid components placed in a mold cavity, applying an external field to generate stirring near the solid/liquid interface to wash off bubbles and oxide particles that prevent the liquid material from reacting to the solid component, and causing progressive solidification from the surfaces of the solid component to the liquid to drive away bubbles in the mushy zone near the bonding region. High quality metallurgical bonds are formed within the composite casting after the liquid solidifies. The resultant large composite casting has minimal defects, such as pores and oxides, at the interfaces between the solidified material and the solid objects. |
| FILED | Wednesday, July 01, 2020 |
| APPL NO | 16/919054 |
| CURRENT CPC | Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 11/115 (20130101) Original (OR) Class B22D 21/04 (20130101) Alloys C22C 21/02 (20130101) C22C 23/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001495 | Knox et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Wayne H. Knox (Rochester, New York); Ruiting Huang (Rochester, New York) |
| ABSTRACT | Methods of designing a laser writing system for modifying a plurality of ophthalmic devices, and systems designed in accordance with those methods. One example of such a method includes: (a) determining at least one material characteristic of the ophthalmic devices, determined over a range of laser writing system parameters; (b) determining at least one design characteristic of the ophthalmic device; and (c) using at least the determined material and design characteristics, configuring at least one system parameter of the laser writing system to optimize throughput of the laser writing system, the laser writing system including: (i) a laser configured to generate a laser beam, (ii) a splitter configured to split the laser beam into a plurality of outputs, and (iii) a plurality of writing heads, each writing head configured to direct at least one of the outputs to an ophthalmic device to write one or more localized refractive index modifications into the ophthalmic device. |
| FILED | Thursday, November 14, 2019 |
| APPL NO | 17/293740 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/16 (20130101) A61F 2/142 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/53 (20151001) Original (OR) Class B23K 26/0624 (20151001) B23K 26/0673 (20130101) B23K 26/705 (20151001) Optical Elements, Systems, or Apparatus G02B 27/144 (20130101) G02B 27/146 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/4099 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001530 | SAMEOTO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dan SAMEOTO (Edmonton, Canada); Amit NAGARKAR (Boston, Massachusetts); Daniel J. PRESTON (Cambridge, Massachusetts); Stephanie OYOLA-REYNOSO (Burlington, Massachusetts); George M. WHITESIDES (Newton, Massachusetts) |
| ABSTRACT | An actuator is described, including a first sheet comprising a plurality of first openings,; and a second sheet comprising a plurality of second openings; wherein the first and second sheets are stacked together such that at least one of the first and second openings are misaligned; and the actuator is configured to move from a first state to a second state, wherein in the first state, out-of-plane motion of the first and second sheets is permitted; and in the second state, the first and second sheets as well as the misaligned first and second openings are jammed together to restrict the out-of-plane motion of the first and second sheets. Methods of actuating and making such actuator are also described. |
| FILED | Tuesday, October 29, 2019 |
| APPL NO | 17/289924 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1075 (20130101) Original (OR) Class Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 1/08 (20130101) B32B 3/263 (20130101) B32B 3/266 (20130101) B32B 7/022 (20190101) B32B 2307/732 (20130101) Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 15/103 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001597 | Sodano et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents Of The University Of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Henry A. Sodano (Ann Arbor, Michigan); Ruowen Tu (Ann Arbor, Michigan) |
| ABSTRACT | The disclosure relates to methods of forming three-dimensional (3D) polymeric articles and additive manufacturing apparatuses for the same. The methods include providing a polymeric solution comprising a polymer dissolved in a solvent; providing a non-solvent, wherein the solvent is miscible in the non-solvent, and the polymer is insoluble in the non-solvent; and injecting the polymeric solution into the non-solvent in a pre-determined 3D pattern to provide a 3D polymeric article. |
| FILED | Thursday, July 01, 2021 |
| APPL NO | 17/365099 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/106 (20170801) Original (OR) Class B29C 64/295 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2101/10 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 40/20 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001877 | Welch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gregory Welch (Orlando, Florida); Gerd Bruder (Orlando, Florida) |
| ABSTRACT | Virtual humans exhibit behaviors associated with inputs and outputs of an autonomous control system for medical monitoring of patients. To foster the awareness and trust, the virtual humans exhibit situational awareness via apparent (e.g., rendered) behaviors based on inputs such as physiological vital signs. The virtual humans also exhibit situational control via apparent behaviors associated with outputs such as direct control of devices, functions of control, actions based on high-level goals, and the optional use of virtual versions of conventional physical controls. A dynamic virtual human who continually exhibits awareness of the system state and relevant contextual circumstances, along with the ability to directly control the system, is used to reduce negative feelings associated with the system such as uncertainty, concern, stress, or anxiety on the part of real human patients. |
| FILED | Thursday, September 16, 2021 |
| APPL NO | 17/476597 |
| CURRENT CPC | Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles B60K 35/00 (20130101) B60K 2370/165 (20190501) B60K 2370/175 (20190501) B60K 2370/785 (20190501) B60K 2370/1529 (20190501) Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 40/08 (20130101) Original (OR) Class B60W 50/0098 (20130101) Optical Elements, Systems, or Apparatus G02B 27/0172 (20130101) Electric Digital Data Processing G06F 3/011 (20130101) G06F 3/017 (20130101) Image Data Processing or Generation, in General G06T 13/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002199 | Kawashima et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shiho Kawashima (Brooklyn, New York); AlaEddin Douba (New York, New York) |
| ABSTRACT | Viscosity and static yield stress are significant rheological properties for 3D concrete printing (3DCP), in which process high static yield stress is associated with high buildability and shape stability and low viscosity is associated with extrudability and pumping. The challenge in concrete rheology lies in decoupling the effect of admixtures on these two properties, i.e., achieving high static yield stresses while still maintaining moderately low viscosities. In meeting this challenge, provided here is an additive system of nanoclays and viscosity modifying admixtures that can tailor the rheological properties of cement composites to meet 3DCP performance requirements. Further, because 3DCP is a technology of scales, any additive must meet scalability and stability requirements for construction, i.e., ease of processing in abundance and relatively low cost, and exhibit an extended shelf life. |
| FILED | Friday, July 02, 2021 |
| APPL NO | 17/366697 |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 70/10 (20200101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 14/10 (20130101) C04B 24/383 (20130101) Original (OR) Class C04B 28/02 (20130101) C04B 40/0046 (20130101) C04B 2103/0079 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002497 | ZHANG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Notre Dame du Lac (South Bend, Indiana); Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | University of Notre Dame du Lac (South Bend, Indiana); Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Yizhou ZHANG (South Bend, Indiana); William A. PHILLIP (South Bend, Indiana); Matthew J. WEBBER (South Bend, Indiana); Bryan W. BOUDOURIS (West Lafayette, Indiana) |
| ABSTRACT | A highly permeable sorbent platform based on polysulfone and polystyrene-b-poly(acrylic acid) composite membranes. The membranes possess a fully interconnected network of poly(acrylic acid)-lined pores, which enables the surface chemistry to be tailored through sequential attachment of polyethyleneimine moieties and metal-binding terpyridine ligands. The polyethyleneimine moieties increase the saturation capacity, while the addition of terpyridine enables high-affinity binding to a diversity of transition metal ions. This membrane platform removes such metal contaminants from solution. The metal capture performance of the functionalized membranes persists even in high concentrations of competitive ions. Also, fluorescence quenching of the terpyridine moiety upon metal ion complexation offers an in-situ probe to monitor the extent of sorbent saturation. The permeability, capacity, and affinity of these membranes, with high-density display of a metal-binding ligand, offer a chemically tailored platform to address the challenges that arise in ensuring clean water. |
| FILED | Wednesday, October 30, 2019 |
| APPL NO | 17/289647 |
| CURRENT CPC | Separation B01D 67/0011 (20130101) B01D 67/0013 (20130101) B01D 67/0093 (20130101) B01D 69/02 (20130101) B01D 69/12 (20130101) B01D 69/147 (20130101) B01D 71/40 (20130101) B01D 71/60 (20130101) B01D 71/68 (20130101) B01D 71/80 (20130101) B01D 2325/02 (20130101) B01D 2325/34 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 39/04 (20130101) B01J 39/19 (20170101) B01J 47/12 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/44 (20130101) C02F 2101/20 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 81/024 (20130101) Original (OR) Class Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/2268 (20130101) C08J 5/2287 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002502 | Scott et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Evan A. Scott (Chicago, Illinois); Sean D. Allen (Chicago, Illinois) |
| ABSTRACT | Described herein are flash nanoprecipitation methods capable of encapsulating hydrophobic molecules, hydrophilic molecules, bioactive protein therapeutics, or other target molecules in amphiphilic copolymer nanocarriers. |
| FILED | Monday, September 20, 2021 |
| APPL NO | 17/448151 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/107 (20130101) A61K 9/1273 (20130101) A61K 31/352 (20130101) A61K 31/365 (20130101) A61K 31/436 (20130101) A61K 38/465 (20130101) A61K 47/34 (20130101) A61K 47/36 (20130101) A61K 49/0047 (20130101) A61K 49/0054 (20130101) A61K 49/0065 (20130101) Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/0807 (20130101) B01F 3/0861 (20130101) B01F 5/02 (20130101) B01F 5/0256 (20130101) B01F 13/0059 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/14 (20130101) Original (OR) Class C08J 2371/02 (20130101) C08J 2381/02 (20130101) C08J 2381/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2320/32 (20130101) Enzymes C12Y 301/03001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002740 | Lippman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Zachary Lippman (North Bellmore, New York); Sebastian Soyk (Cold Spring Harbor, New York); Zachary Hartford Lemmon (Cold Spring Harbor, New York) |
| ASSIGNEE(S) | Cold Spring Harbor Laboratory (Cold Spring Harbor, New York) |
| INVENTOR(S) | Zachary Lippman (North Bellmore, New York); Sebastian Soyk (Cold Spring Harbor, New York); Zachary Hartford Lemmon (Huntington Station, New York) |
| ABSTRACT | Aspects of the disclosure relate to plants, such as Solanaceae plants containing one or more of a mutant Solyc04g005320 gene (or a homolog thereof), a mutant Solycl2g038510 gene (or a homolog thereof), and a mutant Solyc03gl14840 gene (or a homolog thereof), as well as methods of producing such plants. In some aspects, such plants have one or more improved traits, such as modified inflorescence architecture, modified flower number, modified fruit number, higher yield, higher quality products, and higher fruit productivity. |
| FILED | Thursday, May 17, 2018 |
| APPL NO | 16/613660 |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 5/08 (20130101) A01H 5/10 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/8213 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002746 | Simon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); The Regents of the University of California (Oakland, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Anne Elizabeth Simon (Bowie, Maryland); Jingyuan Liu (College Park, Maryland); Georgios Vidalakis (Riverside, California); Sohrab Bodaghi (Laguna Niguel, California) |
| ABSTRACT | The present disclosure relates to a single stranded RNA vector suitable for introducing a therapeutic agent, such as a peptide, a protein or a small RNA, into a host plant. The vector does not encode for any movement protein or coat protein, but is capable of capable of systemic and phloem-limited movement and replication within the host plant. |
| FILED | Tuesday, November 12, 2019 |
| APPL NO | 17/291431 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/60 (20200101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/64 (20130101) C12N 15/8218 (20130101) C12N 15/8281 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002768 | Pluskal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| INVENTOR(S) | Tomás Pluskal (Boston, Massachusetts); Jing-Ke Weng (Belmont, Massachusetts) |
| ABSTRACT | Disclosed are methods, compositions, proteins, nucleic acids, cells, vectors, compounds, reagents, and systems for the preparation of kavalactones, flavokavains, and kavalactone and flavokavain biosynthetic intermediates using enzymes expressed in heterologous host cells, such as microorganisms or plants, or using in vitro enzymatic reactions. This invention also provides for the expression of the enzymes by recombinant cell lines and vectors. Furthermore, the enzymes can be components of constructs such as fusion proteins. The kavalactones produced can be utilized to treat anxiety disorder, insomnia, and other psychological and neurological disorders. The flavokavains produced can be utilized to treat various cancers including colon, bladder, and breast cancers. |
| FILED | Wednesday, March 03, 2021 |
| APPL NO | 17/190872 |
| CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/26 (20130101) C12P 17/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002769 | Pluskal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| INVENTOR(S) | Tomás Pluskal (Boston, Massachusetts); Jing-Ke Weng (Belmont, Massachusetts) |
| ABSTRACT | Disclosed are methods, compositions, proteins, nucleic acids, cells, vectors, compounds, reagents, and systems for the preparation of kavalactones, flavokavains, and kavalactone and flavokavain biosynthetic intermediates using enzymes expressed in heterologous host cells, such as microorganisms or plants, or using in vitro enzymatic reactions. This invention also provides for the expression of the enzymes by recombinant cell lines and vectors. Furthermore, the enzymes can be components of constructs such as fusion proteins. The kavalactones produced can be utilized to treat anxiety disorder, insomnia, and other psychological and neurological disorders. The flavokavains produced can be utilized to treat various cancers including colon, bladder, and breast cancers. |
| FILED | Wednesday, March 03, 2021 |
| APPL NO | 17/191051 |
| CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/26 (20130101) C12P 17/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002790 | KISHI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Jocelyn Yoshiko KISHI (Boston, Massachusetts); Sinem K. SAKA (Allston, Massachusetts); Ninning LIU (Boston, Massachusetts); Peng YIN (Boston, Massachusetts) |
| ABSTRACT | Provided herein are methods and compositions related to nucleic acid barcoding. In some aspects, provided herein are methods and compositions for writing, storing, reading, and resetting data, for example, using photocrosslinking and/or a substrate or compressible hydrogel. |
| FILED | Friday, November 01, 2019 |
| APPL NO | 17/289889 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6834 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220003674 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Shuangming Li (Santa Clara, California); Venkat R. Bhethanabotla (Tampa, Florida) |
| ABSTRACT | Chips and metallic nanostructure biosensors comprising a dielectric substrate and discontinuous and disordered metallic nanostructures of flat island shapes thereon are disclosed herein. Also disclosed are methods of making and using the same. |
| FILED | Thursday, July 01, 2021 |
| APPL NO | 17/365818 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/554 (20130101) Original (OR) Class G01N 21/648 (20130101) G01N 21/6408 (20130101) G01N 33/553 (20130101) G01N 33/54346 (20130101) G01N 33/54373 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220003773 | Winter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jessica Winter (Columbus, Ohio); Elizabeth Jergens (Columbus, Ohio); Kil Ho Lee (Columbus, Ohio) |
| ABSTRACT | Disclosed herein are erasable label systems that involve nanocage molecules positioned around nanoparticles, which can be loaded with, bound to, or adsorbed with imaging agents. The nanocages can contain targeting arms composed of ssDNA or ssRNA that can be used to target biomolecules. For DNA or RNA targeting, this can be done directly. Antibodies can be targeted using avidin-biotin coupling to ssDNA or direct ssDNA conjugation to the antibody surface. ssDNA or ssRNA complementary to one of the arms can then be used to “erase” the label. |
| FILED | Friday, November 15, 2019 |
| APPL NO | 17/292955 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/585 (20130101) Original (OR) Class G01N 33/54393 (20130101) G01N 2458/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220003776 | Lara Gutierrez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Juanita M. Lara Gutierrez (Cambridge, Massachusetts); Maier S. Avendano Amado (Cambridge, Massachusetts); Peng Yin (Cambridge, Massachusetts) |
| ABSTRACT | This disclosure provides methods and compositions for detecting intramolecular and intermolecular interactions, such as protein-protein interactions. These methods detect such interactions at sub-diffraction distances, and thus are referred to as super-resolution detection and imaging methods. |
| FILED | Thursday, July 08, 2021 |
| APPL NO | 17/370925 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) C12Q 1/6897 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/6845 (20130101) Original (OR) Class G01N 2458/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220003792 | FAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (Louisville, Kentucky) |
| ASSIGNEE(S) | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (Louisville, Kentucky) |
| INVENTOR(S) | Teresa Whei-Mei FAN (Lexington, Kentucky); Andrew Nicholas LANE (Lexington, Kentucky); Richard M. HIGASHI (Lexington, Kentucky); Michael BOUSAMRA (Louisville, Kentucky) |
| ABSTRACT | Methods to determine the absence or presence of one or more cancer types in an animal are disclosed herein. In some embodiments, amounts of lipids in a sample (e.g., a bodily fluid or treatment thereof) from the animal are used with a predictive model to make the determination. The lipid amounts can be measured, in some instances, using a mass spectrometry system. |
| FILED | Thursday, July 15, 2021 |
| APPL NO | 17/305824 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) Original (OR) Class G01N 33/57488 (20130101) G01N 2570/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220003975 | Hua et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hong Hua (Tucson, Arizona); Rui Zhang (Kirkland, Washington) |
| ABSTRACT | The present invention relates generally to a head-mounted projection display, and more particularly, but not exclusively to a polarized head-mounted projection display including a light engine and a compact, high-performance projection lens for use with reflective microdisplays. |
| FILED | Friday, September 17, 2021 |
| APPL NO | 17/478033 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/30 (20130101) G02B 5/3083 (20130101) G02B 9/34 (20130101) G02B 13/004 (20130101) G02B 13/04 (20130101) G02B 13/16 (20130101) G02B 13/22 (20130101) Original (OR) Class G02B 13/0065 (20130101) G02B 27/0172 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220004670 | King et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan King (Pittsburgh, Pennsylvania); Nancy S. Pollard (Pittsburgh, Pennsylvania); Stelian Coros (Zürich, Switzerland); Kai-Hung Chang (El Cerrito, California); Cornelia Ulrike Bauer (Pittsburgh, Pennsylvania); Dominik Bauer (Pittsburgh, Pennsylvania); Daniele Moro (Boise, Idaho) |
| ABSTRACT | A manipulation device includes an appendage extending from a base, the appendage comprising a flexible material having a resting pose and adapted to be deformed into a plurality of different poses, and at least one tendon attached to an end of the appendage and passing through the base or a portion of the appendage between the base and the distal end, such that actuation of the at least one tendon causes deformation of the appendage from the resting pose to a new pose. Systems and methods for fabricating and optimizing a manipulation device are also provided. |
| FILED | Thursday, October 03, 2019 |
| APPL NO | 17/281817 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 3/04 (20130101) B25J 9/104 (20130101) B25J 13/02 (20130101) B25J 15/0009 (20130101) Electric Digital Data Processing G06F 30/10 (20200101) Original (OR) Class G06F 30/27 (20200101) Computer Systems Based on Specific Computational Models G06N 3/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220004772 | Katoch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sameeksha Katoch (Tempe, Arizona); Pavan Turaga (Tempe, Arizona); Andreas Spanias (Tempe, Arizona); Cihan Tepedelenlioglu (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona) |
| INVENTOR(S) | Sameeksha Katoch (Tempe, Arizona); Pavan Turaga (Tempe, Arizona); Andreas Spanias (Tempe, Arizona); Cihan Tepedelenlioglu (Tempe, Arizona) |
| ABSTRACT | Various embodiments of a cyber-physical system for providing cloud prediction for photovoltaic array control are disclosed herein. |
| FILED | Monday, September 20, 2021 |
| APPL NO | 17/479120 |
| CURRENT CPC | Electric Digital Data Processing G06F 17/16 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00697 (20130101) G06K 9/00718 (20130101) Original (OR) Class G06K 9/00744 (20130101) G06K 9/6202 (20130101) Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) Image Data Processing or Generation, in General G06T 7/246 (20170101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220006482 | He et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Tian HE (Arden Hills, Minnesota); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tian He (Arden Hills, Minnesota); Wenchao Jiang (Singapore, Singapore); Ruofeng Liu (Falcon Heights, Minnesota) |
| ABSTRACT | Systems, devices, and techniques for allowing communication between two or more computing devices are described herein. For example, a method includes receiving, by a first computing device configured to operate in accordance with a first wireless protocol, one or more data packets via one or more signals output by a second computing device according to a second wireless protocol, where the first computing device is not configured to operate in accordance with the second wireless protocol. Additionally, or alternatively, a method includes receiving, by a first computing device configured to operate in accordance with a first wireless protocol, at least one signal including a data packet, wherein a payload of the data packet comprises an indication of a symbol defined in accordance with a second wireless protocol. |
| FILED | Friday, October 25, 2019 |
| APPL NO | 17/309107 |
| CURRENT CPC | Transmission H04B 1/406 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0061 (20130101) H04L 69/22 (20130101) Wireless Communication Networks H04W 4/38 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220006557 | Pierson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Timothy J. Pierson (Hanover, Vermont); Ronald Peterson (Brattleboro, Vermont); David F. Kotz (Brattleboro, Vermont) |
| ABSTRACT | Apparatuses that provide for secure wireless communications between wireless devices under cover of one or more jamming signals. Each such apparatus includes at least one data antenna and at least one jamming antenna. During secure-communications operations, the apparatus transmits a data signal containing desired data via the at least one data antenna while also at least partially simultaneously transmitting a jamming signal via the at least one jamming antenna. When a target antenna of a target device is in close proximity to the data antenna and is closer to the data antenna than to the jamming antenna, the target device can successfully receive the desired data contained in the data signal because the data signal is sufficiently stronger than the jamming signal within a finite secure-communications envelope due to the Inverse Square Law of signal propagation. Various related methods and machine-executable instructions are also disclosed. |
| FILED | Friday, September 17, 2021 |
| APPL NO | 17/477718 |
| CURRENT CPC | Transmission H04B 1/1009 (20130101) Secret Communication; Jamming of Communication H04K 3/42 (20130101) Original (OR) Class H04K 3/43 (20130101) Wireless Communication Networks H04W 4/80 (20180201) H04W 12/033 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220006726 | Michael et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VMware, Inc. (Palo Alto, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nithin Michael (San Francisco, California); Ao Tang (San Francisco, California); Victor de Souza Lima e Silva (San Francisco, California); Thiago Sousa Santos (San Francisco, California); Ning Wu (San Francisco, California); Archit Baweja (San Francisco, California); Ki Suh Lee (San Francisco, California); Yao Wang (San Francisco, California); Andrey Gushchin (San Francisco, California); Sakethnath Are (San Francisco, California) |
| ABSTRACT | A method comprising instantiating virtual routers (VRs) at each of a set of nodes that form a network. Each VR is coupled to the network and to a tenant of the node. The network comprises virtual links in an overlay network provisioned over an underlay network including servers of a public network. The method comprises configuring at least one VR to include a feedback control system comprising at least one objective function that characterizes the network. The method comprises configuring the VR to receive link state data of a set of virtual links of the virtual links, and control routing of a tenant traffic flow of each tenant according to a best route of the network determined by the at least one objective function using the link state data. |
| FILED | Monday, September 13, 2021 |
| APPL NO | 17/474034 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 43/0864 (20130101) H04L 43/0876 (20130101) H04L 45/22 (20130101) Original (OR) Class H04L 45/24 (20130101) H04L 45/745 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20220000609 | Kintzing et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California); The U.S. Government, The Department of Veterans Affairs (Washington, District of Columbia); The Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James Kintzing (San Jose, California); McCutcheon Brandon (Rochester, Minnesota); Nayak Jayakar (Stanford, California) |
| ABSTRACT | Systems and methods are provided for altering the shape of a target tissue structure of a subject, e.g., a nasal septum or other nasal tissue that include securing a first end of a shaping element to tissue adjacent the structure; manipulating the tissue to alter a shape of the structure; and applying a force to the shaping element to maintain the altered shape of the structure. |
| FILED | Thursday, June 10, 2021 |
| APPL NO | 17/344848 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/186 (20130101) Original (OR) Class A61F 2/2875 (20130101) A61F 2002/2885 (20130101) A61F 2210/0014 (20130101) A61F 2220/0016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220000980 | CASTILLO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York); UNITED STATES GOVERNMENT AS REPRESENTED BY THEDEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alesha CASTILLO (New York, New York); Jin Kim MONTCLARE (New York, New York); Kamia PUNIA (Staten Island, New York) |
| ABSTRACT | The present invention provides compositions and methods for treating a disease or disorder associated with bone defects or reduced or abnormal bone formation. |
| FILED | Friday, September 27, 2019 |
| APPL NO | 17/280297 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/663 (20130101) A61K 38/195 (20130101) Original (OR) Class A61K 47/54 (20170801) A61K 47/55 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/08 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220000983 | Jackson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia); University of Miami (Miami, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert M. Jackson (Miami, Florida); Andrew V. Schally (Miami Beach, Florida); Renzhi Cai (Miami, Florida) |
| ABSTRACT | Described herein are compositions and methods for treating pulmonary fibrosis and cancer. The compositions include growth hormone releasing hormone peptides. The methods include reducing lung inflammation, lung scarring, reducing expression of T cell receptor complex genes as well as inhibiting tumor growth. |
| FILED | Friday, August 06, 2021 |
| APPL NO | 17/396577 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/25 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002363 | Matute-Bello et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Government As Represented By The Department of Veterans Affairs (Washington, District of Columbia); University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gustavo Matute-Bello (Seattle, Washington); Osamu Kajikawa (Seattle, Washington) |
| ABSTRACT | Disclosed herein, are peptides capable of inhibiting sFasL activity, and pharmaceutical compositions containing the peptides and methods treating a pulmonary disease. |
| FILED | Friday, July 02, 2021 |
| APPL NO | 17/366844 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) Peptides C07K 14/4703 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20220002597 | Tisserat |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brent Tisserat (WASHINGTON, Illinois) |
| ABSTRACT | The invention relates to bio-based adhesives comprising seed flour and distiller's dried grains and solubles (DDGS). The seed flour may be soybean seed flour, and the bio-based adhesive my contain a 50:50 mixture of seed flour and DDGS. The invention also relates to methods for using such bio-based adhesives in the preparation of composite wood panels. |
| FILED | Wednesday, June 30, 2021 |
| APPL NO | 17/364283 |
| CURRENT CPC | Manufacture by Dry Processes of Articles, With or Without Organic Binding Agents, Made From Particles or Fibres Consisting of Wood or Other Lignocellulosic or Like Organic Material B27N 3/002 (20130101) B27N 3/02 (20130101) B27N 3/08 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 9/00 (20130101) C09J 103/02 (20130101) Original (OR) Class C09J 2400/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220002746 | Simon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); The Regents of the University of California (Oakland, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Anne Elizabeth Simon (Bowie, Maryland); Jingyuan Liu (College Park, Maryland); Georgios Vidalakis (Riverside, California); Sohrab Bodaghi (Laguna Niguel, California) |
| ABSTRACT | The present disclosure relates to a single stranded RNA vector suitable for introducing a therapeutic agent, such as a peptide, a protein or a small RNA, into a host plant. The vector does not encode for any movement protein or coat protein, but is capable of capable of systemic and phloem-limited movement and replication within the host plant. |
| FILED | Tuesday, November 12, 2019 |
| APPL NO | 17/291431 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/60 (20200101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/64 (20130101) C12N 15/8218 (20130101) C12N 15/8281 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220005606 | Aly et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sharif Aly (Tulare, California); Gabriele Maier (Woodland, California); Sasha Dubrovsky (Sacramento, California) |
| ABSTRACT | Provided are methods of determining the risk of bovine respiratory disease (BRD) in pre-weaned dairy calves on a dairy farm. In certain aspects, the methods include extracting dairy farm management practice information from a dairy farm, wherein the dairy farm management practice information comprises one or more items of information for two or more dairy farm management practice categories selected from the group consisting of: basic herd risk profile, maternity pen management, colostrum management, milk feeding, vaccinations, and calf housing. In certain aspects, the methods further include assigning weighted risk scores to the items of dairy farm management practice information extracted, and determining a total risk score for each of the two or more dairy farm management practice categories based on the assigned weighted risk scores. Also provided are non-transitory computer-readable media and computer devices that find use, e.g., in practicing the methods of the present disclosure. |
| FILED | Wednesday, November 13, 2019 |
| APPL NO | 17/292645 |
| CURRENT CPC | Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/30 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20220000974 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Oncolmmune, Inc. (Rockville, Maryland); Children's Research Institute, Children's National Medical Center (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yang Liu (Washington, District of Columbia); Pan Zheng (Washington, District of Columbia); Xu Wang (Washington, District of Columbia); Martin Devenport (Gaithersburg, Maryland) |
| ABSTRACT | Provided herein are methods and compositions for lowering low-density lipoprotein cholesterol or glucose levels, and for treating subjects with prediabetes or diabetes by targeting CD24-Siglec interactions. |
| FILED | Wednesday, February 05, 2020 |
| APPL NO | 17/428784 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/177 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/06 (20180101) A61P 3/10 (20180101) Peptides C07K 14/70596 (20130101) C07K 2319/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220001441 | Han |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Qingyou Han (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Qingyou Han (West Lafayette, Indiana) |
| ABSTRACT | A method of forming high quality metallurgical bonds in a composite casting is provided. The bonding technology of this invention includes the step of introducing a liquid material to contact the solid components placed in a mold cavity, applying an external field to generate stirring near the solid/liquid interface to wash off bubbles and oxide particles that prevent the liquid material from reacting to the solid component, and causing progressive solidification from the surfaces of the solid component to the liquid to drive away bubbles in the mushy zone near the bonding region. High quality metallurgical bonds are formed within the composite casting after the liquid solidifies. The resultant large composite casting has minimal defects, such as pores and oxides, at the interfaces between the solidified material and the solid objects. |
| FILED | Wednesday, July 01, 2020 |
| APPL NO | 16/919054 |
| CURRENT CPC | Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 11/115 (20130101) Original (OR) Class B22D 21/04 (20130101) Alloys C22C 21/02 (20130101) C22C 23/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220006221 | van Welie et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ingrid van Welie (Newton, Massachusetts); Leonard Kogos (Salem, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ingrid van Welie (Newton, Massachusetts); Leonard Kogos (Salem, Massachusetts) |
| ABSTRACT | The invention relates to an apparatus, system and method for a direct flex cable to flex cable connection, with guides through which the said flex cables are aligned upon insertion and a pressing mechanism which in its latched state perfectly aligns corresponding guides to each other and by extension also aligns corresponding contact pads on the flex cables, and brings them into firm electrical contact. |
| FILED | Friday, July 03, 2020 |
| APPL NO | 16/920503 |
| CURRENT CPC | Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 12/79 (20130101) Original (OR) Class H01R 12/91 (20130101) H01R 12/774 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 20220002001 | Washington, II et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | William J. Washington, II (North Potomac, Maryland); Christian Jordan (Baltimore, Maryland) |
| ABSTRACT | A bag unlocking method includes receiving, by a bag handling system, a bag during a check-in process. The bag handling system identifies, from a travel carrier system, traveler information corresponding to the bag. A securing device of the bag is programmed, using an unlock code pertaining to the traveler information. The bag handling system reads a bag tag of the bag at a baggage inspection station and determines the unlock code pertaining to the bag tag. The bag handling system transmits the unlock code to cause the securing device to unlock at the baggage inspection station. |
| FILED | Monday, September 20, 2021 |
| APPL NO | 17/479766 |
| CURRENT CPC | Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 1/366 (20130101) Original (OR) Class B64F 1/368 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220005049 | Boyd et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Daniel Boyd (Arlington, Virginia); Arun Vemury (North Bethesda, Maryland) |
| ABSTRACT | Systems and methods are described, and an example method includes storing, in an access control memory of an access control computer system a set of access control identity records, receiving from an individual a proffered biographic information, and comparing the proffered biographic information to the access control identity records, In response to the comparing indicating a subset of than one access control identity records having biographic information having similarity to the proffered biographic information exceeding a threshold, generating and sending to a central resource computer system a biometric comparison request. The request includes the proffered biographic information of the persons, an indication of the biometric information of the person, and indication of biographic information in the identity records in the subset, A response is received from the central resource computer indicating whether a central resource identity record includes both a matching identity record biographic information and a matching identity record biometric information. |
| FILED | Friday, September 17, 2021 |
| APPL NO | 17/478552 |
| CURRENT CPC | Electric Digital Data Processing G06F 16/22 (20190101) G06F 21/32 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/06037 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 20/40145 (20130101) Original (OR) Class G06Q 50/265 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20220003665 | SWENSON et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Charles Swenson (North Logan, Utah); Alan Marchant (North Logan, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Charles SWENSON (North Logan, Utah); Alan MARCHANT (North Logan, Utah) |
| ABSTRACT | A system and methods for optically detecting a target atmospheric gas are disclosed and described. An imaging system can include a narrow-band optical interference filter with a center wavelength that corresponds to a feature in an absorption spectrum of a target gas at a normal angle of incidence. An optical component can receive incoming light from the target gas that has passed through the narrow-band optical interference filter, wherein the narrow-band optical interference filter is tilted relative to the optical component, which tilt shifts the wavelength of light from each target point that is able to pass through the narrow-band optical interference filter. A camera can receive the incoming light that has been focused by the optical component. Multiple image frames are collected for different orientations of the system with respect to the target and analyzed to perform hyperspectral characterization of target gas absorption. |
| FILED | Thursday, May 27, 2021 |
| APPL NO | 17/332914 |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/42 (20130101) G01J 3/108 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/3504 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220003678 | Adell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Philippe C. Adell (Pasadena, California); Harry A. Atwater (South Pasadena, California) |
| ABSTRACT | The disclosed technology generally relates to characterization of semiconductor structures, and more particularly to optical characterization of high-k dielectric materials. A method includes providing a semiconductor structure comprising a semiconductor and a high-k dielectric layer formed over the semiconductor, wherein the dielectric layer has electron traps formed therein. The method additionally includes at least partially transmitting an incident light having an incident energy through the high-k dielectric layer and at least partially absorbing the incident light in the semiconductor. The method additionally includes measuring a nonlinear optical spectrum resulting from the light having the energy different from the incident energy, the nonlinear optical spectrum having a first region and a second region, wherein the first region changes at a different rate in intensity compared to the second region. The method further includes determining from the nonlinear optical spectrum one or both of a first time constant from the first region and a second time constant from the second region, and determining a trap density in the high-k dielectric layer based on the one or both of the first time constant and the second time constant. |
| FILED | Tuesday, January 12, 2021 |
| APPL NO | 17/147371 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/636 (20130101) G01N 21/6489 (20130101) Original (OR) Class G01N 21/8851 (20130101) G01N 21/9501 (20130101) G01N 21/9505 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 29/24 (20130101) G01R 31/302 (20130101) G01R 31/2648 (20130101) G01R 31/2656 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 22/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 20220000256 | TARTAL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES POSTAL SERVICE (WASHINGTON, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | William A. TARTAL (Baltimore, Maryland); Joel L. DEWNANDAN (Bladensburg, Maryland); Joram SHENHAR (Fairfax, Virginia) |
| ABSTRACT | A portable workstation apparatus includes: a pair of collapsible legs. Each leg incudes a frame, a first extension, a second extension, a lower post housed within a sleeve, an upper post, a hinge connecting the lower post and the upper post, a first brace connecting the first extension to the sleeve, a second brace connecting the second extension to the sleeve, multiple holes on an exterior face of the lower post or the upper post. Each leg is configured to collapse by folding the upper post towards the lower post via the hinge and rotating the first extension and the second extension toward the lower post. The apparatus further includes a height-adjustable desk portion capable of being attached to the pair of collapsible legs via a pair of brackets and capable of being removed from the pair of collapsible legs. |
| FILED | Tuesday, June 29, 2021 |
| APPL NO | 17/362236 |
| CURRENT CPC | Tables; Desks; Office Furniture; Cabinets; Drawers; General Details of Furniture A47B 3/08 (20130101) Original (OR) Class A47B 9/14 (20130101) A47B 21/02 (20130101) A47B 83/04 (20130101) A47B 2003/0824 (20130101) A47B 2009/145 (20130101) A47B 2200/004 (20130101) A47B 2200/0029 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220005297 | Tartal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | William Albert Tartal (Baltimore, Maryland); Gabriel Michael Yessin (Arlington, Virginia); Robert E. Dalton, JR. (Greenville, South Carolina) |
| ABSTRACT | Locking systems and devices and methods for using the systems and devices are provided. A locking system may include a receptacle having a lock and an electronic credential. If the electronic credential is brought into proximity of the receptacle, then a key can be used to open the lock. The electronic credential can be incorporated into a vehicle or into a handheld device. |
| FILED | Monday, September 20, 2021 |
| APPL NO | 17/448182 |
| CURRENT CPC | Locks; Accessories Therefor; Handcuffs E05B 47/026 (20130101) Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere G07C 9/00309 (20130101) Original (OR) Class G07C 9/00912 (20130101) G07C 2009/00396 (20130101) G07C 2009/00769 (20130101) G07C 2009/00968 (20130101) G07C 2209/63 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 20220003221 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Na Li (Richardson, Texas); Carter S. Haines (Murphy, Texas); Marco D. Lima (Richardson, Texas); Monica Jung DeAndrade (Richardson, Texas); Shaoli Fang (Richardson, Texas); Jiyoung Oh (Richardson, Texas); Mikhail E. Kozlov (Dallas, Texas); Dongseok Suh (Plano, Texas); Ray H. Baughman (Dallas, Texas) |
| ABSTRACT | Actuators (artificial muscles) comprising twist-spun nanofiber yarn or twist-inserted polymer fibers generate actuation when powered electrically, photonically, chemically, thermally, by absorption, or by other means. These artificial muscles utilize polymer fibers non-coiled or coiled yarns and can be either neat or comprising a guest. Devices comprising these artificial muscles are also described. In some embodiments, thermally-powered polymer fiber torsional actuator has a twisted, chain-oriented polymer fiber that has a first degree of twist at a first temperature and a second degree of twist at a second temperature in which the bias angles of the first degree and second degree of twist are substantially different. |
| FILED | Tuesday, September 21, 2021 |
| APPL NO | 17/480635 |
| CURRENT CPC | Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0007 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 6/00 (20130101) Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads D02G 3/02 (20130101) D02G 3/26 (20130101) D02G 3/448 (20130101) Braiding or Manufacture of Lace, Including Bobbin-net or Carbonised Lace; Braiding Machines; Braid; Lace D04C 1/02 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2401/046 (20130101) D10B 2401/061 (20130101) D10B 2509/00 (20130101) Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 7/06 (20130101) Original (OR) Class Electric Machines Not Otherwise Provided for H02N 10/00 (20130101) H02N 11/006 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2925 (20150115) Y10T 428/249921 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 20220006504 | Robinson |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rampart Communications, Inc. (Annapolis, Maryland) |
| ASSIGNEE(S) | Rampart Communications, Inc. (Annapolis, Maryland) |
| INVENTOR(S) | Matthew Brandon Robinson (Crownsville, Maryland) |
| ABSTRACT | A processor coupled to a first communication device produces and transmits a first encoded vector and a second encoded vector to a second communication device via a communication channel that applies a channel transformation to the encoded vectors during transmission. A processor coupled to the second communication device receives the transformed signals, constructs a matrix based on the transformed signals, detects an effective channel thereof, and identifies left and right singular vectors of the effective channel. A precoding matrix is selected from a codebook of unitary matrices based on a message, and a second encoded vector is produced based on a second known vector, the precoding matrix, a complex conjugate of the left singular vectors, and the right singular vectors. A first symbol of the second encoded vector and a second symbol of the second encoded vector are sent to the first communication device for identification of the message. |
| FILED | Friday, September 17, 2021 |
| APPL NO | 17/478099 |
| CURRENT CPC | Transmission H04B 7/0417 (20130101) H04B 7/0456 (20130101) H04B 7/0634 (20130101) Original (OR) Class H04B 7/0639 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, January 06, 2022.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2021/details-patents-20210427.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page