FedInvent™ Patent Applications
Application Details for Thursday, January 13, 2022
This page was updated on Monday, January 17, 2022 at 04:35 PM GMT
Department of Health and Human Services (HHS)
US 20220007939 | Dave et al. |
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FUNDED BY |
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APPLICANT(S) | PlenOptika, Inc. (Cambridge, Massachusetts) |
ASSIGNEE(S) | |
INVENTOR(S) | Shivang R. Dave (Boston, Massachusetts); Daryl Lim (Singapore, Singapore); Nicholas James Durr (Baltimore, Maryland) |
ABSTRACT | An apparatus, and corresponding method, for determining a property of an eye includes a housing with a proximal port that receives an eye and also light from the eye. The housing further includes a distal port, and the two ports together form a visual channel providing an open view to enable the eye to see target indicia external to and spaced away from the housing. A wavefront sensor within the housing is configured to receive the light from the eye via the optical path and to measure a wavefront of the light. A determination module determines an objective refractive correction based on the wavefront and predicts a subjective refractive preference of a person having the eye based on the objective refractive correction. Embodiments can be handheld, and binocular, and predict subjective refraction based on demographic and other information. |
FILED | Tuesday, July 20, 2021 |
APPL NO | 17/380891 |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/005 (20130101) A61B 3/0008 (20130101) A61B 3/09 (20130101) A61B 3/18 (20130101) Original (OR) Class A61B 3/028 (20130101) A61B 3/0033 (20130101) A61B 3/103 (20130101) A61B 3/0285 (20130101) A61B 3/1208 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220007943 | Sanchez et al. |
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APPLICANT(S) | ENSPECTRA HEALTH, INC. (Mountain View, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Gabriel Sanchez (Menlo Park, California); Fred Landavazo, IV (Redwood City, California); Kathryn Montgomery (Mountain View, California); Piyush Arora (San Carlos, California) |
ABSTRACT | Provided herein are methods, devices, and systems that may improve optical resolution when imaging through a thickness of samples. A method for generating a depth profile of a tissue of a subject may comprise using an optical probe to transmit an excitation light beam from a light source towards a surface of the tissue; using one or more focusing units in the optical probe to simultaneously adjust a depth and a position of a focal point of the excitation light beam along a scanning path; detecting at least a subset of the signals generated upon contacting the tissue with the excitation light beam; and using one or more computer processors programmed to process the at least the subset of the signals to generate the depth profile of the tissue. |
FILED | Tuesday, May 11, 2021 |
APPL NO | 17/317661 |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0071 (20130101) A61B 5/0075 (20130101) Original (OR) Class A61B 5/0084 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/10016 (20130101) G06T 2207/10028 (20130101) G06T 2207/30024 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220007969 | Balter et al. |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
ASSIGNEE(S) | |
INVENTOR(S) | James Balter (Ann Arbor, Michigan); Yue Cao (Ann Arbor, Michigan); Lianli Liu (Ann Arbor, Michigan); Adam Johnsson (Uppsala, Sweden) |
ABSTRACT | The following relates generally to motion prediction in magnetic resonance (MR) imaging. In some embodiments, a “modular” approach is taken to motion correction. That is, individual motion sources (e.g., a patient's breathing, heartbeat, stomach contractions, peristalsis, and so forth) are accounted for individually in the motion correction. In some embodiments, to correct for a particular motion source, a reference state is created from a volume of interest (VOI), and other states are created and deformably aligned to the reference state. |
FILED | Wednesday, June 30, 2021 |
APPL NO | 17/364845 |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/113 (20130101) A61B 5/1107 (20130101) Original (OR) Class A61B 5/1128 (20130101) A61B 6/466 (20130101) A61B 6/4042 (20130101) Image Data Processing or Generation, in General G06T 7/207 (20170101) G06T 2207/10088 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220007991 | ROBERTS et al. |
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APPLICANT(S) | The Trustees of Dartmouth College (Hanover, New Hampshire) |
ASSIGNEE(S) | |
INVENTOR(S) | David W. ROBERTS (Lyme, New Hampshire); Keith D. PAULSEN (Hanover, New Hampshire); Alexander HARTOV (Enfield, New Hampshire); Songbai JI (Hanover, New Hampshire); Xiaoyao FAN (Lebanon, New Hampshire) |
ABSTRACT | A surgical guidance system has two cameras to provide stereo image stream of a surgical field; and a stereo viewer. The system has a 3D surface extraction module that generates a first 3D model of the surgical field from the stereo image streams; a registration module for co-registering annotating data with the first 3D model; and a stereo image enhancer for graphically overlaying at least part of the annotating data onto the stereo image stream to form an enhanced stereo image stream for display, where the enhanced stereo stream enhances a surgeon's perception of the surgical field. The registration module has an alignment refiner to adjust registration of the annotating data with the 3D model based upon matching of features within the 3D model and features within the annotating data; and in an embodiment, a deformation modeler to deform the annotating data based upon a determined tissue deformation. |
FILED | Monday, September 27, 2021 |
APPL NO | 17/486839 |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/0077 (20130101) A61B 5/377 (20210101) Original (OR) Class A61B 2034/104 (20160201) Image Data Processing or Generation, in General G06T 3/0068 (20130101) G06T 7/33 (20170101) Pictorial Communication, e.g Television H04N 13/239 (20180501) H04N 13/257 (20180501) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220007997 | MANNOH et al. |
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APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
ASSIGNEE(S) | |
INVENTOR(S) | Emmanuel A. MANNOH (Nashville, Tennessee); Anita MAHADEVAN-JANSEN (Nashville, Tennessee) |
ABSTRACT | A combined auto-fluorescence imaging and laser speckle contrast imaging (LSCI) system to enable intra-operative parathyroid identification and viability assessment with the same tool. The system includes a light source for emitting a beam of light to illuminate a target of interest, and an imaging head positioned over the target of interest for individually acquiring auto-fluorescence images and LSCI images of light from the illuminated target of interest responsive to the illumination. Auto-fluorescence imaging helps identify the parathyroid, while LSCI helps assess its viability. |
FILED | Monday, November 04, 2019 |
APPL NO | 17/289323 |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0071 (20130101) A61B 5/0075 (20130101) A61B 5/0086 (20130101) A61B 5/415 (20130101) Original (OR) Class A61B 5/418 (20130101) A61B 5/742 (20130101) A61B 5/4227 (20130101) A61B 34/20 (20160201) A61B 2034/2055 (20160201) A61B 2505/05 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) G01N 21/6456 (20130101) G01N 2021/6439 (20130101) G01N 2201/0221 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008060 | Gittard et al. |
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APPLICANT(S) | Muffin Incorporated (West Lafayette, Indiana); National Institutes of Health, an Agency of the Department of Health and Human Services (Bethesda, Maryland) |
ASSIGNEE(S) | Muffin Incorporated (West Lafayette, Indiana); National Institutes of Health, an Agency of the Department of Health and Human Services (Bethesda, Maryland) |
INVENTOR(S) | Shaun Davis Gittard (Winston-Salem, North Carolina); Gregory James Hardy (Asheville, North Carolina); John C. Sigmon, JR. (Winston-Salem, North Carolina); Jeremy T. Newkirk (West Lafayette, Indiana); William J. Havel (West Lafayette, Indiana); Neal E. Fearnot (West Lafayette, Indiana); Toby Rogers (Washington, District of Columbia); Kanishka Ratnayaka (Bethesda, Maryland); Robert L. Lederman (Chevy Chase, Maryland) |
ABSTRACT | Among other things, there is disclosed structure and methods for maintaining access to a location in the body while reducing or eliminating the potential for pulling an access device (e.g. a catheter) back through an opening. An introducer sheath includes a distal indented portion and a balloon, so that once placed in a desired location through tissue, the balloon can be inflated to anchor the sheath against retraction. In particular embodiments, structure and methods for accessing the pericardial cavity via the right atrial appendage are shown. |
FILED | Monday, July 26, 2021 |
APPL NO | 17/385230 |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/0218 (20130101) Original (OR) Class A61B 90/39 (20160201) A61B 2017/3486 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/10 (20130101) A61M 25/0041 (20130101) A61M 25/0045 (20130101) A61M 2025/0047 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008346 | Wilson et al. |
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APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
ASSIGNEE(S) | |
INVENTOR(S) | John T. Wilson (Nashville, Tennessee); Daniel Shae (Nashville, Tennessee); Dinh Chuong Nguyen (Phu Nhuan District, Ho Chi Minh, Viet Nam) |
ABSTRACT | A graft copolymer and a method of delivering an active agent to a subject are provided. The graft copolymer includes a polymer backbone, a hydrophilic segment grafted to the polymer backbone, a pH-responsive segment grafted to the polymer backbone, and an endosomal disruption segment grafted to the polymer backbone. The method of delivering an active agent to a subject includes encapsulating the active agent with the graft copolymer and administering the encapsulated active agent to the subject. |
FILED | Wednesday, October 30, 2019 |
APPL NO | 17/290618 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5026 (20130101) Original (OR) Class Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 290/062 (20130101) C08F 2438/03 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008350 | VISHWANATHA et al. |
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APPLICANT(S) | University of North Texas Health Science Center (Fort Worth, Texas) |
ASSIGNEE(S) | University of North Texas Health Science Center (Fort Worth, Texas) |
INVENTOR(S) | Jamboor K. VISHWANATHA (Fort Worth, Texas); Andrew GDOWSKI (Fort Worth, Texas); Amalendu Prakash RANJAN (Fort Worth, Texas); Anindita MUKERJEE (Fort Worth, Texas) |
ABSTRACT | Certain embodiments are directed to methods for making programmable bioinspired nanoparticles (P-BiNP). Nanoparticles are coated with a cell membrane derived from a cell stimulated to express or overexpress a protein identified as being expressed in a target cell, forming a homotypic and organ targeted nanoparticle delivery vehicle. |
FILED | Wednesday, October 16, 2019 |
APPL NO | 17/309030 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5153 (20130101) A61K 9/5176 (20130101) Original (OR) Class A61K 9/5192 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008365 | Daniels et al. |
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APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
ASSIGNEE(S) | |
INVENTOR(S) | Anthony B. Daniels (Nashville, Tennessee); Debra L. Friedman (Nashville, Tennessee) |
ABSTRACT | Methods of treating a proliferative conditions of the eye, comprising administering to a patient a therapeutically effective amount of a composition that comprises a compound that inhibits the biological activity of a mammalian histone deacetylase (HDAC), or a pharmaceutically acceptable salt thereof; and a pharmaceutical carrier. |
FILED | Thursday, November 14, 2019 |
APPL NO | 17/294339 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/165 (20130101) Original (OR) Class A61K 31/4045 (20130101) A61K 31/4406 (20130101) A61K 38/15 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008368 | CHUN et al. |
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FUNDED BY |
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APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
INVENTOR(S) | Eunyoung CHUN (Brookline, Massachusetts); Wendy Sarah GARRETT (Brookline, Massachusetts) |
ABSTRACT | Described herein are methods, assays, and compositions and uses thereof related to treating, preventing, and detecting a gastrointestinal disease with an agent that targets Ffar2. The agents described herein can further increase populations of group 3 innate lymphoid cells (ILC3s) in the gut. |
FILED | Thursday, November 14, 2019 |
APPL NO | 17/293840 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/19 (20130101) Original (OR) Class A61K 31/426 (20130101) A61K 31/513 (20130101) A61K 38/177 (20130101) A61K 48/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/04 (20180101) A61P 29/00 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) G01N 33/5047 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008376 | LU |
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APPLICANT(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
ASSIGNEE(S) | |
INVENTOR(S) | Wuyuan LU (Clarkville, Maryland) |
ABSTRACT | Type 3 Secretion System (T3 SS) inhibitors, tanshinones and tanshinone analogs, and methods of using the same for the treatment of disease are disclosed. The invention relates generally to antibiotic compounds and methods of treating or preventing bacterial infections using the same, and more particularly, but not exclusively, to compounds that inhibit biogenesis of the Type 3 Secretion System (T3 SS) needle, including tanshinone and tanshinone analogs, and methods of using the same. |
FILED | Friday, November 01, 2019 |
APPL NO | 17/290691 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/343 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008408 | Zhou et al. |
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APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
INVENTOR(S) | Pei Zhou (Durham, North Carolina); Jiyong Hong (Durham, North Carolina) |
ABSTRACT | This invention relates to compounds, pharmaceutical compositions comprising them, and methods of using the compounds and compositions for treating diseases related to translesion synthesis (TLS) pathway. More particularly, this disclosure relates to small molecule inhibitors of TLS, methods of inhibiting TLS pathway with these compounds, and methods of treating diseases related to the TLS pathway. |
FILED | Wednesday, October 09, 2019 |
APPL NO | 17/283461 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4706 (20130101) Original (OR) Class A61K 33/243 (20190101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008418 | Rawat et al. |
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APPLICANT(S) | The McLean Hospital Corporation (Belmont, Massachusetts); University of Delhi (Delhi, India) |
ASSIGNEE(S) | |
INVENTOR(S) | Diwan S. Rawat (Delhi, India); Sunny Manohar (Delhi, India); Ummadisetty Chinna Rajesh (Delhi, India); DEEPAK KUMAR (Delhi, India); Anuj Thakur (Delhi, India); Mohit Tripathi (Delhi, India); Panyala Linga Reddy (Delhi, India); Shamseer Kulangara Kandi (Delhi, India); Satyapavan Vardhineni (Delhi, India); Kwang-Soo Kim (Lexington, Massachusetts); Chun-Hyung Kim (Lexington, Massachusetts) |
ABSTRACT | Described herein are aminoquinoline and aminoacridine based hybrids, pharmaceutical compositions and medicaments that include such aminoquinoline and aminoacridine based hybrids, and methods of using such compounds for diagnosing and/or treating infections, neurodegerative diseases or disorders, inflammation, inflammation associated diseases and disorders, and/or diseases or disorders that are treatable with dopamine agonists such as the restless leg syndrome. |
FILED | Monday, April 26, 2021 |
APPL NO | 17/240886 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) Original (OR) Class A61K 31/5355 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 401/12 (20130101) C07D 401/14 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) C12N 2506/02 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008420 | BRADNER et al. |
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APPLICANT(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts); DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
ASSIGNEE(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts); DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
INVENTOR(S) | James BRADNER (Weston, Massachusetts); Jun QI (Sharon, Massachusetts); Dennis BUCKLEY (Cambridge, Massachusetts); Leonard I. ZON (Brookline, Massachusetts); Elizabeth MACARI (Wilmington, Massachusetts) |
ABSTRACT | The present invention relates to methods, compositions and kits for treatment of ribosomal disorders and ribosomopathies, e.g. Diamond Blackfan anemia (DBA). In some embodiments, the invention relates to the use of novel classes of compounds, i.e. inhibitors of RSK (p90S6K); inhibitors of p70S6K; and inhibitors of rps6, to treat ribosomal disorders and ribosomopathies. In some embodiments, the invention relates to the use of specific Chk2 inhibitors and to the use of specific phenothiazine derivatives to treat ribosomal disorders and ribosomopathies, e.g. DBA. |
FILED | Friday, February 12, 2021 |
APPL NO | 17/175079 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) A61K 31/225 (20130101) A61K 31/403 (20130101) A61K 31/506 (20130101) A61K 31/517 (20130101) Original (OR) Class A61K 31/519 (20130101) A61K 31/5415 (20130101) A61K 31/7048 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/06 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008429 | UEHARA et al. |
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APPLICANT(S) | Shionogi and Co., Ltd. (Osaka-shi, Osaka, Japan); F. HOFFMANN-LA ROCHE AG (Basel, Switzerland) |
ASSIGNEE(S) | |
INVENTOR(S) | Takeki UEHARA (Osaka, Japan); Toru ISHIBASHI (Osaka, Japan); Takao SHISHIDO (Osaka, Japan); Keita FUKAO (Osaka, Japan); Motoyasu OONISHI (Osaka, Japan); Barry CLINCH (Welwyn Garden City, United Kingdom); Jaspinder RANDHAWA (Welwyn Garden City, United Kingdom) |
ABSTRACT | A method for treating an influenza virus infection is described. The disclosed method generally involves administering an effective amount of a compound (A), for example baloxavir marboxil, and a compound (B), for example a neuraminidase inhibor, to a subject that (1) has an influenza virus infection, (2) has been symptomatic of the influenza virus infection for no more than 96 hours, and (3) further has at least one severe influenza condition selected from the following: (a) being hospitalized due to severe influenza virus infection, (b) requiring an extension of hospitalization because of the influenza virus infection during the hospitalization, (c) having a National Early Warning Score 2 of four or more, (d) being on support for respiration, and (e) having at least one complication attributable to the influenza virus infection that necessitates hospitalization. |
FILED | Friday, March 20, 2020 |
APPL NO | 16/825263 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/215 (20130101) A61K 31/5383 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/16 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008433 | Edge et al. |
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APPLICANT(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts) |
ASSIGNEE(S) | |
INVENTOR(S) | Albert Edge (Brookline, Massachusetts); Niliksha Gunewardene (Boston, Massachusetts) |
ABSTRACT | Methods for the generation of sensorineural hair cells, and more particularly to the use of epigenetic modulation of Atoh1 expression using a combination of Histone Lysine Demethylase (KDM) inhibitors and Wnt activators to generate sensorineural hair cells. |
FILED | Tuesday, November 26, 2019 |
APPL NO | 17/296764 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) Original (OR) Class A61K 31/137 (20130101) A61K 31/506 (20130101) A61K 45/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008442 | Otto et al. |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | |
INVENTOR(S) | Mario Otto (Fitchburg, Wisconsin); Dana C. Baiu (Madison, Wisconsin); Bryan P. Bednarz (Madison, Wisconsin); Jamey Paul Weichert (Sun Prairie, Wisconsin) |
ABSTRACT | It is disclosed herein that that certain alkylphosphocholine analogs are preferentially taken up by malignant pediatric tumor cells. The alkylphophocholine analogs are compounds having the formula: or salts thereof, wherein n is an integer from 12 to 24; and R2 is —N+(CH3)3. The compounds can be used to treat pediatric solid tumors or to detect pediatric solid tumors. In therapeutic treatment, R1 includes a radioactive iodine isotope that locally delivers therapeutic dosages of radiation to the malignant pediatric tumor cells that preferentially take up the compound. In detection/imaging applications, R1 includes a detection moiety, such as a fluorophore or a radioactive iodine isotope. |
FILED | Tuesday, September 21, 2021 |
APPL NO | 17/480239 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/69 (20130101) A61K 31/685 (20130101) Original (OR) Class A61K 31/6615 (20130101) A61K 33/18 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57407 (20130101) G01N 33/57484 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008443 | O'CONNOR et al. |
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FUNDED BY |
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APPLICANT(S) | Washington State University (Pullman, Washington); Tufts Medical Center, Inc. (Boston, Massachusetts); University of Utah Research Foundation (Salt Lake City, Utah) |
ASSIGNEE(S) | |
INVENTOR(S) | Roberta O'CONNOR (Pullman, Washington); Eric W. SCHMIDT (Salt Lake City, Utah) |
ABSTRACT | Methods and compositions for preventing and/or treating diseases and conditions caused by certain apicomplexan infections are provided. The methods involve administering/providing to a subject one or more of tartrolon D and E, including isomers thereof. Exemplary apicomplexan infections that are prevented/treated by the compounds of the invention include those caused by Cryptosporidium, Babesia, Cyclospora, Isospora, Plasmodium, Sarcocystis, Besnoitia, Hammondia, Neospora, Theileria and Toxoplasma. |
FILED | Friday, August 27, 2021 |
APPL NO | 17/459985 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/69 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 33/06 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008452 | CHUN et al. |
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APPLICANT(S) | YALE UNIVERSITY (NEW HAVEN, Connecticut) |
ASSIGNEE(S) | |
INVENTOR(S) | Hyung CHUN (Guilford, Connecticut); Takaomi ADACHI (East Haven, Connecticut) |
ABSTRACT | In various aspects and embodiments the invention provides compositions and methods useful in the treatment of certain metabolic diseases, such as but not limited to NASH, NAFLD, diabetes, atherosclerosis, and/or obesity. |
FILED | Friday, December 06, 2019 |
APPL NO | 17/311502 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/04 (20180101) A61P 3/10 (20180101) A61P 9/10 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008500 | Kay et al. |
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APPLICANT(S) | The George Washington University (Washington, District of Columbia); The U.S. Government as represented by The Department of Veterans Affairs (Washington, District of Columbia) |
ASSIGNEE(S) | |
INVENTOR(S) | Matthew Kay (Kensington, Maryland); Kara Garrott (Washington, District of Columbia); Jhansi Dyavanapalli (Gaithersburg, Maryland); David Mendelowitz (Vienna, Virginia); Gregory Trachiotis (Arlington, Virginia) |
ABSTRACT | Methods of treating a subject having heart failure including heart failure with reduced ejection fraction, heart failure with preserved ejection fraction, and left ventricular hypertrophy-induced heart failure. The methods include activating hypothalamic oxytocin neurons in the brain of the subject and/or administering intranasally to the subject a therapeutically effective amount of oxytocin. Intranasal formulations for the treatment of a subject diagnosed with heart failure are also provided. |
FILED | Wednesday, June 16, 2021 |
APPL NO | 17/349771 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0043 (20130101) A61K 38/095 (20190101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008504 | Fang et al. |
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APPLICANT(S) | The Methodist Hospital (Houston, Texas) |
ASSIGNEE(S) | The Methodist Hospital (Houston, Texas) |
INVENTOR(S) | Longhou Fang (Katy, Texas); Qilin Gu (Quincy, Massachusetts) |
ABSTRACT | Embodiments of the present disclosure pertain to methods of reducing hematopoiesis in a subject by administering to the subject a therapeutically effective amount of an inhibitor of Srebp2. Additional embodiments of the present disclosure pertain to compositions for reducing hematopoiesis in a subject. In some embodiments, the compositions include a therapeutically effective amount of an inhibitor of Srebp2. Further embodiments of the present disclosure pertain to methods of enhancing hematopoiesis in a subject by administering to the subject a therapeutically effective amount of an active ingredient. Additional embodiments of the present disclosure pertain to compositions for enhancing hematopoiesis in a subject. In some embodiments, the compositions of the present disclosure include active ingredients that enhance hematopoiesis in the subject. |
FILED | Wednesday, January 29, 2020 |
APPL NO | 17/297543 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/22 (20130101) A61K 31/40 (20130101) A61K 31/047 (20130101) A61K 31/47 (20130101) A61K 31/366 (20130101) A61K 31/405 (20130101) A61K 31/505 (20130101) A61K 31/4418 (20130101) A61K 31/4439 (20130101) A61K 31/7105 (20130101) A61K 38/177 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/06 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008512 | SHIRWAN et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (Louisville, Kentucky); FASCURE THERAPEUTICS, LLC (Louisville, Kentucky) |
ASSIGNEE(S) | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (Louisville, Kentucky); FASCURE THERAPEUTICS, LLC (Louisville, Kentucky) |
INVENTOR(S) | Haval SHIRWAN (Columbia, Missouri); Esma S. YOLCU (Columbia, Missouri); Rajesh SHARM (San Diego, California) |
ABSTRACT | Described herein are methods for treating and preventing cancer. In particular, described herein are methods using SA-4-1BBL as a monotherapy agent to treat, prevent or reduce the risk of cancer, treat, prevent, or reduce the risk of tumorigenesis, and treat, prevent, or reduce the risk of post-surgical tumor recurrence. SA-4-1BBL for use as a monotherapy in such methods also is provided. |
FILED | Friday, November 15, 2019 |
APPL NO | 17/294157 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/191 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008520 | Ambrosio et al. |
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FUNDED BY |
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APPLICANT(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | |
INVENTOR(S) | Fabrisia Ambrosio (Pittsburgh, Pennsylvania); Aaron Barchowsky (Pittsburgh, Pennsylvania); Amin Cheikhi (Pittsburgh, Pennsylvania); Rada Koldamova (Bethel Park, Pennsylvania); Iliya Lefterov (Bethel Park, Pennsylvania); Amrita Sahu (Pittsburgh, Pennsylvania) |
ABSTRACT | This document provides methods and materials for treating aging. For example, a mammal having, or at risk for developing, an age-related impairment (e.g., age-related cognitive decline) can be treated by increasing the level of one or more myokine polypeptides (e.g., one or more Klotho polypeptides) within cells within the mammal. This document also provides methods and materials for increasing the ability of muscle progenitor cells to regenerate muscle cells by increasing the level(s) of one or more myokine polypeptides (e.g., an α-Klotho polypeptide) within a muscle progenitor cell. |
FILED | Thursday, November 21, 2019 |
APPL NO | 17/294726 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 38/47 (20130101) Original (OR) Class A61K 48/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/06 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008523 | Shea et al. |
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FUNDED BY |
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APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
ASSIGNEE(S) | |
INVENTOR(S) | Lonnie D. Shea (Evanston, Illinois); Stephen D. Miller (Evanston, Illinois); Jonathan Woon Teck Yap (Evanston, Illinois); Daniel R. Getts (Northbrook, Illinois); Derrick McCarthy (Evanston, Illinois) |
ABSTRACT | The present invention provides compositions comprising peptide-coupled biodegradable poly(lactide-co-glycolide) (PLG) particles. In particular, PLG particles are surface-functionalized to allow for coupling of peptide molecules to the surface of the particles (e.g., for use in eliciting induction of immunological tolerance). |
FILED | Wednesday, September 22, 2021 |
APPL NO | 17/482043 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/19 (20130101) A61K 9/1647 (20130101) A61K 9/5153 (20130101) A61K 39/00 (20130101) A61K 39/0008 (20130101) Original (OR) Class A61K 47/58 (20170801) A61K 47/6911 (20170801) A61K 47/6935 (20170801) A61K 47/6937 (20170801) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008535 | Zaghouani |
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FUNDED BY |
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APPLICANT(S) | The Curators of the University of Missouri (Columbia, Missouri) |
ASSIGNEE(S) | |
INVENTOR(S) | Habib Zaghouani (Columbia, Missouri) |
ABSTRACT | The disclosure relates generally to methods and compositions of treating or preventing diabetes mellitus by administering to a subject a composition comprising an amount of stem and/or progenitor cells and at least one antigen-specific therapy. |
FILED | Friday, September 03, 2021 |
APPL NO | 17/466097 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) A61K 35/545 (20130101) A61K 38/10 (20130101) A61K 38/51 (20130101) A61K 38/1774 (20130101) A61K 39/39533 (20130101) Original (OR) Class A61K 2039/505 (20130101) Peptides C07K 16/18 (20130101) C07K 2318/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008543 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
ASSIGNEE(S) | |
INVENTOR(S) | Dong Wang (Omaha, Nebraska); Steven R. Goldring (Auburndale, Massachusetts); Gang Zhao (Omaha, Nebraska); Rongguo Ren (Omaha, Nebraska); Zhenshan Jia (Omaha, Nebraska); Xin Wei (Omaha, Nebraska) |
ABSTRACT | This application discloses prodrug-based thermosensitive gel (“ProGel”) comprised of conjugates of dmg molecules with water-soluble polymeric carriers, which are capable of controlled release of the dmg molecules into the tissue of a subject. Use of the ProGel-Drug conjugates for treatment of various diseases or disorders and methods of preparing them are also disclosed. |
FILED | Sunday, October 27, 2019 |
APPL NO | 17/288814 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/55 (20170801) A61K 47/58 (20170801) Original (OR) Class A61K 47/545 (20170801) A61K 47/554 (20170801) A61K 47/6903 (20170801) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008560 | KAPILOFF et al. |
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FUNDED BY |
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APPLICANT(S) | University of Miami (Miami, Florida); The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
ASSIGNEE(S) | University of Miami (Miami, Florida); The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Michael KAPILOFF (Los Altos, California); Jinliang LI (Palo Alto, California) |
ABSTRACT | The present invention provides a method of treating heart failure with reduced ejection fraction, by administering to a patient at risk of such damage, a pharmaceutically effective amount of a composition which inhibits the anchoring of PP2A to mAKAPβ. This composition is preferably in the form of a viral based gene therapy vector that encodes a fragment of mAKAPβ to which PP2A binds. |
FILED | Friday, March 13, 2020 |
APPL NO | 16/818771 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/761 (20130101) A61K 48/0066 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/04 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008563 | Mukherjee et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Jogeshwar Mukherjee (Irvine, California); Christopher Liang (Irvine, California); Phuc Quang Lam (Irvine, California); Rommani Mondal (Chino Hills, California); Stephanie Martinez (Irvine, California) |
ABSTRACT | The disclosure provides compounds for detecting neurodegeneration and/or identifying and monitoring the progression of inflammation in neurodegenerative diseases. The disclosure further provides compounds that inhibit the activity of monoamine oxidases, and uses thereof. |
FILED | Friday, July 09, 2021 |
APPL NO | 17/372410 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/0455 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) General Methods of Organic Chemistry; Apparatus Therefor C07B 59/002 (20130101) Heterocyclic Compounds C07D 471/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/60 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008567 | Chilkoti et al. |
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FUNDED BY |
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APPLICANT(S) | Duke University (Durham, North Carolina) |
ASSIGNEE(S) | |
INVENTOR(S) | Ashutosh Chilkoti (Durham, North Carolina); Jeffrey L. Schaal (Durham, North Carolina); Wenge Liu (Durham, North Carolina) |
ABSTRACT | Described herein are compositions for liquidly injectable, self-stabilizing biopolymers for the delivery of radionuclide brachytherapy. Also described herein are methods of using the compositions. |
FILED | Wednesday, November 13, 2019 |
APPL NO | 17/294368 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/088 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008701 | Langer et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Robert S. Langer (Newton, Massachusetts); Carlo Giovanni Traverso (Newton, Massachusetts); Ester Caffarel Salvador (Cambridge, Massachusetts); Sahab Babaee (Arlington, Massachusetts); Simo Pajovic (Mississauga, Canada) |
ABSTRACT | Systems and methods related to reconfigurable medical devices are described. In some embodiments, a reconfigurable medical device may include a central core and a plurality of arms. The arms may be rotatably coupled to the central core such that the plurality of arms may rotate outwards away from the central core to selectively reconfigure the reconfigurable device between a retracted configuration and an expanded configuration. In an initial state, the arms may be biased outwards away from the central core into the expanded configuration. When the reconfigurable device is exposed to a temperature greater than a threshold temperature, the arms may be biased towards the central core into the retracted configuration. In some embodiments, a reconfigurable medical device may include therapeutic compound-loaded needles coupled to distal portions of the arms. |
FILED | Friday, November 15, 2019 |
APPL NO | 17/293799 |
CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 31/002 (20130101) Original (OR) Class A61M 37/00 (20130101) A61M 2205/0266 (20130101) A61M 2210/105 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008748 | Huang et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Charles Huang (San Diego, California); Lei Xing (Palo Alto, California) |
ABSTRACT | A method for radiation therapy treatment planning includes: a) defining a decision variable search space by projecting an initial seed point onto a pareto front, where the pareto front and decision variable search space are defined in the same coordinate space; b) projecting search points in the decision variable search space to the pareto front using a one-dimensional search algorithm to produce projected points on the pareto front; c) updating the search points by performing a gradient-free optimization that evaluates a treatment planning scoring function at the projected points on the pareto front; and d) repeating steps (b), (c) to search within the decision variable search space until a convergence criterion is satisfied, thereby producing a pareto optimal and clinically acceptable treatment plan. |
FILED | Thursday, July 08, 2021 |
APPL NO | 17/370383 |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1031 (20130101) Original (OR) Class A61N 5/1077 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008926 | Cameron et al. |
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FUNDED BY |
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APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
INVENTOR(S) | Craig Eugene Cameron (State College, Pennsylvania); Wu Liu (State College, Pennsylvania) |
ABSTRACT | The present invention provides microfluidic devices capable of sequestering single particles in individual microchambers and isolating the particles from one another. The devices provide a plurality of channels fluidly connected to a plurality of microchambers. A fluid suspension comprising particles of interest can be passed through the devices in a first direction to sequester single particles in each microchamber. An isolating fluid can be passed through the devices in a second, reverse direction to isolate the particles from one another. The devices can selectively isolate several particles in each microchamber. |
FILED | Tuesday, July 06, 2021 |
APPL NO | 17/367827 |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) Original (OR) Class B01L 2200/0652 (20130101) B01L 2300/16 (20130101) B01L 2300/168 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/405 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220009124 | Xiao et al. |
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FUNDED BY |
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APPLICANT(S) | Clemson University Research Foundation (Clemson, South Carolina) |
ASSIGNEE(S) | |
INVENTOR(S) | Hai Xiao (Clemson, South Carolina); Jianhua Tong (Central, South Carolina); Fei Peng (Clemson, South Carolina); Kyle S. Brinkman (Clemson, South Carolina); Shenglong Mu (Clemson, South Carolina); Jincheng Lei (Clemson, South Carolina); Yuzhe Hong (Clemson, South Carolina); Hua Huang (Clemson, South Carolina); Rajendra Bordia (Seneca, South Carolina) |
ABSTRACT | A method for fabricating a protonic ceramic energy device includes: coating an electrolyte layer on an anode layer; and densifying the electrolyte layer by a rapid laser reactive sintering (RLRS) process on the electrolyte layer and/or the anode layer to form a half-cell comprising a dense electrolyte and a porous anode. |
FILED | Wednesday, December 30, 2020 |
APPL NO | 17/138173 |
CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/402 (20130101) B23K 2103/52 (20180801) Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 1/001 (20130101) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 40/20 (20200101) Manufacture, Shaping, or Supplementary Processes C03B 19/01 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220009891 | KWON et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Oyhun KWON (Los Angeles, California); Qihai XU (Los Angeles, California); Nathan J. DUPPER (Los Angeles, California); Jau-Nian CHEN (Los Angeles, California); Adam D. LANGENBACHER (Los Angeles, California) |
ABSTRACT | R-aplexone, methods of preparing R-aplexone, or aplexone substantially free of its S-stereoisomer are disclosed. Methods of using R-aplexone or a pharmaceutically acceptable salt or solvate thereof to treat and/or prevent disease are disclosed. Methods of preparing 6-substituted tetrahydropyridine motifs with high enantiomeric excess are also disclosed. |
FILED | Thursday, September 19, 2019 |
APPL NO | 17/278230 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Heterocyclic Compounds C07D 211/96 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220009905 | ARANCIO et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York); Northwestern University (Evanston, Illinois) |
ASSIGNEE(S) | |
INVENTOR(S) | Ottavio ARANCIO (New York, New York); Daniel Martin WATTERSON (Douglas, Michigan); Jeffrey Claude PELLETIER (Lafayette Hill, Pennsylvania); Saktimayee Mitra ROY (Evanston, Illinois) |
ABSTRACT | The invention provides for novel MAP kinase inhibitors and compositions comprising the same. In some embodiments, the MAP kinase inhibitors are p38α MAP kinase inhibitors. The invention further provides for methods for treatment of diseases comprising administration of MAP kinase inhibitors or compositions comprising MAP kinase inhibitors. In some embodiments, the disease is Alzheimer's Disease, ALS, Huntington's Disease or Parkinson's Disease. |
FILED | Thursday, September 16, 2021 |
APPL NO | 17/476648 |
CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Heterocyclic Compounds C07D 401/04 (20130101) C07D 401/14 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220009914 | Johnson et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Indiana University (Indianapolis, Indiana); ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
ASSIGNEE(S) | |
INVENTOR(S) | Steven Johnson (Indianapolis, Indiana); Eli Chapman (Tucson, Arizona) |
ABSTRACT | Novel compounds and methods of killing or inhibiting the growth of bacteria. |
FILED | Thursday, July 01, 2021 |
APPL NO | 17/365390 |
CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Acyclic or Carbocyclic Compounds C07C 251/86 (20130101) C07C 2602/10 (20170501) Heterocyclic Compounds C07D 215/12 (20130101) C07D 215/26 (20130101) C07D 215/28 (20130101) C07D 307/52 (20130101) C07D 307/73 (20130101) C07D 401/12 (20130101) C07D 405/12 (20130101) C07D 409/12 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220009941 | Natarajan et al. |
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FUNDED BY |
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APPLICANT(S) | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska) |
ASSIGNEE(S) | |
INVENTOR(S) | Amarnath Natarajan (Elkhorn, Nebraska); Sandeep Rana (Omaha, Nebraska) |
ABSTRACT | Provided herein are compounds and methods for modulating the NFκB pathway. More particularly, provided are inhibitors of the NFκB pathway and the uses of such inhibitors in regulating diseases and disorders, e.g., to treat cancer, autoimmune diseases, inflammatory diseases, diabetes, cardiovascular diseases, or neurological diseases. |
FILED | Wednesday, July 21, 2021 |
APPL NO | 17/382083 |
CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 487/10 (20130101) C07D 491/107 (20130101) Original (OR) Class C07D 519/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220009967 | Franzblau |
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FUNDED BY |
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APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
INVENTOR(S) | Scott G. Franzblau (Chicago, Illinois) |
ABSTRACT | Provided herein are compounds having a structure according to formula I, pharmaceutical compositions thereof, and methods of treating a bacterial infection thereof. |
FILED | Tuesday, July 13, 2021 |
APPL NO | 17/305713 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 7/64 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220009977 | Cherqui |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Stephanie Cherqui (La Jolla, California) |
ABSTRACT | Provided herein are methods for treating a disease or disorder associated with mitochondrial dysfunction through ex vivo introduction of a nucleic acid molecule into hematopoietic stem and progenitor cells (HSPCs) followed by transplantation of the HSPCs into a subject in need of treatment. The nucleic acid molecule may include a functional human frataxin (hFXN) or may include a gene editing system that when transfected into the cells removes a trinucleotide extension mutation of endogenous hFXN. |
FILED | Friday, September 24, 2021 |
APPL NO | 17/484324 |
CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0276 (20130101) A01K 67/0278 (20130101) A01K 2207/15 (20130101) A01K 2217/05 (20130101) A01K 2217/15 (20130101) A01K 2217/075 (20130101) A01K 2227/105 (20130101) A01K 2267/0318 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Peptides C07K 14/47 (20130101) Original (OR) Class C07K 2319/60 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/86 (20130101) C12N 2310/20 (20170501) C12N 2740/16043 (20130101) C12N 2800/80 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220009980 | Zhuang et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
ASSIGNEE(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
INVENTOR(S) | Zhengping Zhuang (Bethesda, Maryland); Emeline Tabouret (Marseille, France); Herui Wang (McLean, Virginia); Harish Pant (Rockville, Maryland); Niranjana D. Amin (Clarksburg, Maryland) |
ABSTRACT | Methods of decreasing cell viability of cancer cells, increasing apoptosis of cancer cells, and treating cancer in a mammal with cancer are provided. The methods include administering (i) a polypeptide comprising an amino acid sequence with at least 95% sequence identity to the amino acid sequence of SEQ ID NO: 1, (ii) a nucleic acid molecule comprising a nucleic acid sequence encoding the polypeptide, (iii) a vector comprising the nucleic acid molecule, (iv) a recombinant cell comprising any one of (i)-(iii), and/or (v) a composition comprising any one of (i)-(iv). |
FILED | Wednesday, November 13, 2019 |
APPL NO | 17/294011 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4745 (20130101) A61K 38/00 (20130101) Peptides C07K 14/4703 (20130101) Original (OR) Class C07K 14/4738 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220009991 | Antipov et al. |
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FUNDED BY |
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APPLICANT(S) | Silver Creek Pharmaceuticals, Inc. (San Francisco, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Laura D.J. Antipov (Oakland, California); Shawdee Eshghi (Oakland, California); Kristopher M. Kuchenbecker (Phoenix, Arizona); Bjorn L. Millard (Orinda, California); Matthew D. Onsum (El Cerrito, California); Andrea D. Nickerson (San Francisco, California); Timothy R. Stowe (San Francisco, California); Yan Zhang (San Francisco, California) |
ABSTRACT | Bi-specific fusion proteins with therapeutic uses are provided, as well as pharmaceutical compositions comprising such fusion proteins, and methods for using such fusion proteins to repair or regenerate damaged or diseased tissue. |
FILED | Tuesday, September 28, 2021 |
APPL NO | 17/487120 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/47 (20130101) C07K 14/65 (20130101) Original (OR) Class C07K 14/765 (20130101) C07K 2319/035 (20130101) C07K 2319/75 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010019 | Swirski et al. |
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FUNDED BY |
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APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
ASSIGNEE(S) | |
INVENTOR(S) | Filip K. Swirski (Swampscott, Massachusetts); Shun He (Malden, Massachusetts) |
ABSTRACT | Methods and compositions of treating patients with metabolic syndrome or a disease associated with metabolic syndrome using inhibitors that target natural intraepithelial lymphocytes. |
FILED | Tuesday, November 26, 2019 |
APPL NO | 17/297153 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/26 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/2839 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010273 | Gabrilovich |
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FUNDED BY |
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APPLICANT(S) | The Wistar Institute of Anatomy and Biology (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | |
INVENTOR(S) | Dmitry I. Gabrilovich (Villanova, Pennsylvania) |
ABSTRACT | Provided herein are methods of generating MDSCs ex vivo. The methods include culturing blood cells with lactoferrin. |
FILED | Tuesday, August 13, 2019 |
APPL NO | 17/291808 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/15 (20130101) A61K 38/40 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/06 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0634 (20130101) Original (OR) Class C12N 2501/73 (20130101) C12N 2501/2306 (20130101) C12N 2506/11 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010279 | QUACH et al. |
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FUNDED BY |
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APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York); THE GEORGE WASHINGTON UNIVERSITY (Washington, District of Columbia) |
ASSIGNEE(S) | |
INVENTOR(S) | Bonnie QUACH (Ithaca, New York); Trine KROGH-MADSEN (Ithaca, New York); David J. CHRISTINI (Ithaca, New York); Emilia ENTCHEVA (Washington, District of Columbia) |
ABSTRACT | The present disclosure is directed to kits and methods for performing optical dynamic clamping on an excitable cell. In some embodiments, the excitable cell is selected from the group consisting of a neuron, a muscle cell and an excitable cell derived from an induced Pluripotent Stem Cell (IPSC). In a specific embodiment, the muscle cell is a cardiomyocyte. |
FILED | Tuesday, October 01, 2019 |
APPL NO | 17/282181 |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) C12N 5/0657 (20130101) Original (OR) Class C12N 5/0696 (20130101) C12N 2506/45 (20130101) C12N 2529/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010282 | Karp et al. |
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APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
ASSIGNEE(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
INVENTOR(S) | Jeffrey Karp (Boston, Massachusetts); Amit Choudhary (Boston, Massachusetts); Kisuk Yang (Boston, Massachusetts); Miseon Lee (Cambridge, Massachusetts); Peter Jones (Cambridge, Massachusetts) |
ABSTRACT | 3D cell cultures and devices for 3D cell culture, and methods of use thereof are provided. In some embodiments, the 3D cell culture comprise pancreatic β cells and can be generated in multi-well plates, allowing for high throughput assays on the cell culture. |
FILED | Wednesday, June 16, 2021 |
APPL NO | 17/349646 |
CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/12 (20130101) C12M 23/24 (20130101) C12M 23/48 (20130101) C12M 25/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0677 (20130101) Original (OR) Class C12N 2513/00 (20130101) C12N 2533/30 (20130101) C12N 2533/52 (20130101) C12N 2533/54 (20130101) C12N 2533/90 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010284 | Silpe et al. |
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APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
INVENTOR(S) | Justin E. Silpe (Lawrenceville, New Jersey); Bonnie L. Bassler (Princeton, New Jersey) |
ABSTRACT | Disclosed are recombinant phages that infect and kill bacterial hosts in response to user-defined inputs. The components that encode the user-defined inputs can be combined, such that multiple inputs are maintained on a single recombinant phage, enabling precise control over the targeting strategy. The phages can be engineered to kill a specific bacterial species or multiple species simultaneously. Recombinant phages can also be engineered to harbor fluorescent and bioluminescent reporter genes that enable them to be used for tracking, detection, and in biosensing applications. Recombinant phages can also be used to lyse bacterial cells that produce recombinant proteins, as a rapid method to enable extraction and high-level purification of potentially valuable and/or industrially important proteins. Also disclosed is a system that can also be used to control the activity of a protein of interest, by taking advantage of an interaction between Qtip and a phage repressor protein; a phage repressor protein can be fused to a protein-of-interest, and by controlling the expression of qtip, the phage repressor protein fused to a protein-of-interest will be inactivated when Qtip is expressed and interacts with the phage repressor protein. |
FILED | Thursday, October 31, 2019 |
APPL NO | 17/289336 |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 15/73 (20130101) C12N 15/74 (20130101) C12N 2795/10121 (20130101) C12N 2795/10122 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010285 | LIU |
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FUNDED BY |
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APPLICANT(S) | BioVentures, LLC (Little Rock, Arkansas) |
ASSIGNEE(S) | BioVentures, LLC (Little Rock, Arkansas) |
INVENTOR(S) | Jia LIU (Little Rock, Arkansas) |
ABSTRACT | The present disclosure provides compositions and methods for increasing the production of virus in vitro. Modified cells which are modified to eliminate or reduce as compared to a control cell the activity or expression of a Sterile a motif-domain containing protein 9 (SAMD9) polypeptide are provided. Methods of using these cells are also provided. |
FILED | Wednesday, November 20, 2019 |
APPL NO | 17/295761 |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 9/22 (20130101) C12N 15/111 (20130101) C12N 2710/24052 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010299 | Das et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Rhiju Das (Palo Alto, California); Christian A. Choe (Stanford, California); Hannah K. Wayment-Steele (Stanford, California); Wipapat Kladwang (Stanford, California) |
ABSTRACT | Embodiments herein describe systems and methods to enhance RNA translation and stability and uses thereof. Many embodiments generate RNA molecules possessing increased structure and/or reduced free energy over an initial sequence. Such RNA molecules can be used as therapeutics and/or vaccines. |
FILED | Thursday, July 01, 2021 |
APPL NO | 17/364890 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7115 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/102 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010300 | Wyss-Coray et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Anton Wyss-Coray (Palo Alto, None); Carolyn R. Bertozzi (Menlo Park, California); Julia Marschallinger (Palo Alto, California); Michael S. Haney (Mountain View, California) |
ABSTRACT | Methods of treating a subject for a neurodegenerative disorder are provided. Aspects of the methods include administering to a subject in need thereof an effective amount of an agent that reduces the prevalence of lipid droplet accumulating microglia (LAM) to treat the subject for the neurodegenerative disorder. A variety of neurodegenerative disorders may be treated by practice of the methods. Also provided are methods of identifying lipid droplet-associated target genes, including target genes that are positive and negative regulators of lipid droplet formation, as well as methods of treating a neurodegenerative disorder in a subject by administering to the subject an antagonist of a positive regulator of lipid droplet formation and/or an agonist of a negative regulator of lipid droplet formation. |
FILED | Thursday, January 09, 2020 |
APPL NO | 17/413360 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) Peptides C07K 16/18 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1037 (20130101) Original (OR) Class C12N 2310/14 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010302 | Mirkin et al. |
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FUNDED BY |
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APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
ASSIGNEE(S) | |
INVENTOR(S) | Chad A. Mirkin (Wilmette, Illinois); Gokay Yamankurt (Chicago, Illinois); Milan Mrksich (Hinsdale, Illinois); Eric J. Berns (Park Ridge, Illinois); Neda Bagheri (Chicago, Illinois); Albert Xue (Chicago, Illinois); Andrew Lee (Evanston, Illinois) |
ABSTRACT | The present disclosure provides methods for the rapid synthesis of large libraries of spherical nucleid acid (SNA) nanoparticles, their screening for activity, and a machine learning algorithm to analyze the data. |
FILED | Friday, April 12, 2019 |
APPL NO | 17/046482 |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1086 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010307 | Mischel et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California); Ludwig Institute for Cancer Research Ltd (La Jolla, California); The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Paul Mischel (La Jolla, California); Bing Ren (La Jolla, California); Kristen Turner (La Jolla, California); Sihan Wu (La Jolla, California); Vineet Bafna (Oakland, California); Nam-phuong Nguyen (Oakland, California); Howard Chang (Stanford, California) |
ABSTRACT | Provided herein are, inter alia, methods and compositions to detect, monitor and treat cancer, wherein the cancer includes amplified extrachromosomal oncogenes. The methods are useful for personalized treatment and exploit differential expression and chromatin structure of extrachromosomal oncogenes in cancer cells. |
FILED | Tuesday, December 10, 2019 |
APPL NO | 17/311980 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) Original (OR) Class C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2310/20 (20170501) C12N 2320/31 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010309 | Khvorova et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
ASSIGNEE(S) | |
INVENTOR(S) | Anastasia Khvorova (Westborough, Massachusetts); Loïc Maurice René Jean Roux (Worcester, Massachusetts); Ken Yamada (Boston, Massachusetts) |
ABSTRACT | This disclosure relates to the synthesis of novel modified oligonucleotides. The synthesis of novel phosphoramidites are also provided. |
FILED | Friday, March 26, 2021 |
APPL NO | 17/213852 |
CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/067 (20130101) C07H 21/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/314 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010310 | Feinberg et al. |
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FUNDED BY |
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APPLICANT(S) | The Brigham and Women`s Hospital, Inc. (Boston, Massachusetts) |
ASSIGNEE(S) | |
INVENTOR(S) | Mark W. Feinberg (Newton, Massachusetts); Stefan Haemmig (Brookline, Massachusetts) |
ABSTRACT | Methods and compositions for use in treating subjects suffering from a disease associated with a malfunction in DNA repair response using compositions that comprise or encode SNHG12 long non-coding RNA. |
FILED | Tuesday, November 12, 2019 |
APPL NO | 17/291922 |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/317 (20130101) C12N 2310/321 (20130101) C12N 2310/3521 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010312 | Mueller et al. |
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FUNDED BY |
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APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
INVENTOR(S) | Christian Mueller (Concord, Massachusetts); Neil Aronin (Newtonville, Massachusetts); Edith L. Pfister (Boxborough, Massachusetts) |
ABSTRACT | Aspects of the disclosure relate to compositions and methods useful for treating Huntington's disease. In some embodiments, the disclosure provides interfering nucleic acids (e.g., artificial miRNAs) targeting the huntingtin gene (HTT) and methods of treating Huntington's disease using the same. |
FILED | Friday, May 21, 2021 |
APPL NO | 17/326400 |
CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/141 (20130101) C12N 2310/3519 (20130101) C12N 2330/51 (20130101) C12N 2750/14121 (20130101) C12N 2750/14141 (20130101) C12N 2750/14143 (20130101) C12N 2750/14171 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010313 | Friedland et al. |
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FUNDED BY |
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APPLICANT(S) | EDITAS MEDICINE, INC. (Cambridge, Massachusetts) |
ASSIGNEE(S) | EDITAS MEDICINE, INC. (Cambridge, Massachusetts) |
INVENTOR(S) | Ari E. Friedland (Boston, Massachusetts); Penrose O'Donnell (Yarmouth, Maine); David A. Bumcrot (Belmont, Massachusetts) |
ABSTRACT | CRISPR/CAS-related systems, compositions and methods for editing RS1, RL2, and/or LAT genes in human cells are described, as are cells and compositions including cells edited according to the same. |
FILED | Monday, April 19, 2021 |
APPL NO | 17/234145 |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/102 (20130101) C12N 15/1133 (20130101) Original (OR) Class C12N 2310/10 (20130101) C12N 2310/20 (20170501) C12N 2800/80 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010317 | BORDENSTEIN et al. |
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FUNDED BY |
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APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee); lNSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNI (Paris, France); THE UNIVERSITY OF CHICAGO (Chicago, Israel) |
ASSIGNEE(S) | |
INVENTOR(S) | Sarah BORDENSTEIN (Nashville, Tennessee); Julie REVEILLAUD (Montpellier, France); A. Murat EREN (Chicago, Illinois); Seth BORDENSTEIN (Nashville, Tennessee) |
ABSTRACT | The present disclosure relates to plasmids, systems, and methods for the transformation of Wolbachia. Disclosed herein are plasmids and systems for use in methods of transforming Wolbachia. The inventors have identified extrachromosomal plasmids within Wolbachia. Disclosed herein is a non-naturally occurring plasmid comprising a nucleic acid encoding a transposase. Disclosed herein is a method for transforming a Wolbachia cell, comprising introducing a non-naturally occurring plasmid into the cell, wherein the plasmid comprises a nucleic acid sequence capable of transforming a Wolbachia cell. |
FILED | Friday, November 15, 2019 |
APPL NO | 17/293634 |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/74 (20130101) Original (OR) Class C12N 2800/101 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010331 | Thomson et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Resarch Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | |
INVENTOR(S) | James Thomson (Madison, Wisconsin); Junying Yu (Middleton, Wisconsin) |
ABSTRACT | Methods for reprogramming primate somatic cells to pluripotency using an episomal vector that does not encode an infectious virus are disclosed. Pluripotent cells produced in the methods are also disclosed. |
FILED | Monday, June 21, 2021 |
APPL NO | 17/352873 |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0696 (20130101) C12N 15/85 (20130101) Original (OR) Class C12N 2501/602 (20130101) C12N 2501/603 (20130101) C12N 2501/604 (20130101) C12N 2501/605 (20130101) C12N 2501/606 (20130101) C12N 2501/608 (20130101) C12N 2510/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010333 | Mali et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Prashant Mali (La Jolla, California); Dhruva Katrekar (La Jolla, California); Dario Meluzzi (La Jolla, California); Genghao Chen (La Jolla, California); Kyle M. Ford (La Jolla, California) |
ABSTRACT | Disclosed herein is a system to recruit ADARs to catalyze therapeutic editing of point mutations via the use of engineered RNA scaffolds, engineered DNA scaffolds or DNA-RNA hybrid scaffolds. The system comprises an engineered ADAR2 guide RNA (adRNA) that bears a 20-100 bp complementarity with the target RNA and ADAR2 recruiting domain from the GluR2 mRNA at either or both the 5′ end or the 3′ end. |
FILED | Friday, September 06, 2019 |
APPL NO | 17/273885 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) A61K 48/0066 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2310/16 (20130101) C12N 2310/531 (20130101) C12N 2320/31 (20130101) C12N 2320/32 (20130101) C12N 2320/33 (20130101) C12N 2320/35 (20130101) C12N 2750/14343 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010335 | RAO et al. |
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FUNDED BY |
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APPLICANT(S) | The Catholic University of America (Washington, District of Columbia) |
ASSIGNEE(S) | |
INVENTOR(S) | Venigalla B. RAO (Silver Spring, Maryland); Jingen ZHU (Washington, District of Columbia) |
ABSTRACT | Described is hybrid viral vector comprising: a first virus such as bacteriophage T4; one or more second virus such as adeno-associated virus (AAV) attached to the first virus through cross-bridges, such as avidin-biotin cross-bridges; one or more DNA molecules packaged in the first virus; one or more nucleic acid molecules packaged in the second virus; and one or more proteins displayed on the surface of the first virus. Also described are methods of making and using such a hybrid viral vector. |
FILED | Wednesday, September 29, 2021 |
APPL NO | 17/488542 |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2750/14133 (20130101) C12N 2750/14134 (20130101) C12N 2795/10133 (20130101) C12N 2795/10134 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010338 | Doudna et al. |
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FUNDED BY |
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APPLICANT(S) | Emmanuelle Charpentier (Berlin, Germany); The Regents of the University of California (Oakland, California); University of Vienna (Vienna, Austria) |
ASSIGNEE(S) | |
INVENTOR(S) | Jennifer A. Doudna (Berkeley, California); Martin Jinek (Berkeley, California); Krzysztof Chylinski (Vienna, Austria); Emmanuelle Charpentier (Berlin, Germany) |
ABSTRACT | The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a polypeptide associated with the target DNA. The present disclosure further provides site-specific modifying polypeptides. The present disclosure further provides methods of site-specific modification of a target DNA and/or a polypeptide associated with the target DNA The present disclosure provides methods of modulating transcription of a target nucleic acid in a target cell, generally involving contacting the target nucleic acid with an enzymatically inactive Cas9 polypeptide and a DNA-targeting RNA. Kits and compositions for carrying out the methods are also provided. The present disclosure provides genetically modified cells that produce Cas9; and Cas9 transgenic non-human multicellular organisms. |
FILED | Tuesday, September 21, 2021 |
APPL NO | 17/481063 |
CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 6/4684 (20180501) Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/027 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/465 (20130101) A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/63 (20130101) C12N 15/70 (20130101) C12N 15/90 (20130101) C12N 15/102 (20130101) C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 15/746 (20130101) C12N 15/902 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/13 (20130101) C12N 2310/20 (20170501) C12N 2310/531 (20130101) C12N 2310/3519 (20130101) C12N 2800/80 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Enzymes C12Y 301/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010339 | ZHANG et al. |
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FUNDED BY |
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APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Feng ZHANG (Cambridge, Massachusetts); Omar O. ABUDAYYEH (Cambridge, Massachusetts); James E. DAHLMAN (Cambridge, Massachusetts); Patrick HSU (Cambridge, Massachusetts); David A. SCOTT (Cambridge, Massachusetts) |
ABSTRACT | The invention provides for systems, methods, and compositions for altering expression of target gene sequences and related gene products. Provided are structural information on the Cas protein of the CRISPR-Cas system, use of this information in generating modified components of the CRISPR complex, vectors and vector systems which encode one or more components or modified components of a CRISPR complex, as well as methods for the design and use of such vectors and components. Also provided are methods of directing CRISPR complex formation in eukaryotic cells and methods for utilizing the CRISPR-Cas system. In particular the present invention comprehends optimized functional CRISPR-Cas enzyme systems, wherein the guide sequence is modified by secondary structure to increase the specificity of the CRISPR-Cas system and whereby the secondary structure can protect against exonuclease activity and allow for 5′ additions to the guide sequence. |
FILED | Wednesday, September 29, 2021 |
APPL NO | 17/489308 |
CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) A01K 2217/07 (20130101) A01K 2227/105 (20130101) Peptides C07K 14/4702 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/96 (20130101) C12N 15/11 (20130101) C12N 15/111 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/20 (20170501) Enzymes C12Y 301/21004 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010365 | Wolff et al. |
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FUNDED BY |
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APPLICANT(S) | The Government of the USA as represented by the Secretary of the Dept. of Health and Human Services (Atlanta, Georgia) |
ASSIGNEE(S) | The Government of the USA as represented by the Secretary of the Dept. of Health and Human Services (Atlanta, Georgia) |
INVENTOR(S) | Bernard J. Wolff (Roswell, Georgia); Jonas M. Winchell (Lilburn, Georgia); Maureen Diaz (Atlanta, Georgia) |
ABSTRACT | Methods for detecting presence of one or more of Acinetobacter baumannii, Pseudomonas aeruginosa, Klebsiella pneumooniae, Toxoplasma gondii, Moraxella catarrhalis, Escherichia coli, Shigella, Staphylococcus aureus, Pneumocystis jirovecii, Chlamydia trachomatis, Ureaplasma urealyticum, Ureaplasma parvum, Ureaplasma spp., Bartonella spp., Streptococcus agalactiae, and Neisseria meningitidis nucleic acids in a sample, such as a biological sample obtained from a subject, or an environmental sample, are provided. This disclosure also provides probes, primers, and kits for detecting one or more of Acinetobacter baumannii, Pseudomonas aeruginosa, Klebsiella pneumoniae, Toxoplasma gondii, Moraxella catarrhalis, Escherichia coli, Shigella, Staphylococcus aureus, Pneumocystis jirovecii, Chlamydia trachomatis, Ureaplasma urealyticum, Ureaplasma parvum, Ureaplasma spp., Bartonella spp., Streptococcus agalactiae, and Neisseria meningitidis in a sample. |
FILED | Monday, September 27, 2021 |
APPL NO | 17/485953 |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Original (OR) Class C12Q 1/6895 (20130101) C12Q 2600/16 (20130101) C12Q 2600/158 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010376 | SALK et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (SEATTLE, Washington) |
ASSIGNEE(S) | |
INVENTOR(S) | Jesse SALK (Seattle, Washington); Lawrence A. LOEB (Bellevue, Washington); Michael SCHMITT (Seattle, Washington) |
ABSTRACT | Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand. This method uniquely capitalizes on the redundant information stored in double-stranded DNA, thus overcoming technical limitations of prior methods utilizing data from only one of the two strands. |
FILED | Monday, September 27, 2021 |
APPL NO | 17/448973 |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) C12Q 1/6876 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010380 | Hoyo et al. |
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FUNDED BY |
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APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
INVENTOR(S) | Cathrine Hoyo (Raleigh, North Carolina); David Skaar (Raleigh, North Carolina); Dereje Jima (Raleigh, North Carolina); Randy L. Jirtle (Raleigh, North Carolina) |
ABSTRACT | Provided are compositions and methods for determining an imprinting status of a gene subject to parent-of-origin, monoalleleic expression in a subject, and for using the information derived therefrom to detect a presence of and/or a susceptibility to a medical condition associated with monoallelic expression in a subject, predict a susceptibility to future development of a medical condition prior to the onset of any symptoms, monitor the development of such a medical condition and/or the effectiveness of a treatment, and for treating such a medical condition. In some embodiments, a composition for use in the disclosed methods is nucleic acid array, which in some embodiments can include one or more interrogatable nucleotide molecules, wherein the interrogatable nucleotide molecules are designed to allow identification of the DNA methylation status of one or more imprint control regions (ICRs) that regulate one or more genes subject to monoalleleic expression in subjects. |
FILED | Friday, July 09, 2021 |
APPL NO | 17/372113 |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/154 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220011216 | Lo et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Yu-Hwa Lo (San Diego, California); Yuanyuan Han (San Diego, California); Yi Gu (San Diego, California); Ce Zhang (La Jolla, California) |
ABSTRACT | Disclosed are systems, devices and methods for imaging and image-based sorting of particles in a flow system, including cells in a flow cytometer. In some aspects, a system includes a particle flow device to flow particles through a channel, an imaging system to obtain image data of a particle during flow through the channel, a processing unit to determine a property associated with the particle and to produce a control command for sorting the particle based on sorting criteria associated with particle properties, and an actuator to direct the particle into one of a plurality of output paths of the particle flow device in real-time. |
FILED | Thursday, May 20, 2021 |
APPL NO | 17/326312 |
CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/36 (20130101) G01J 3/46 (20130101) G01J 3/51 (20130101) G01J 3/0208 (20130101) G01J 3/0229 (20130101) G01J 3/4406 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/147 (20130101) G01N 15/1429 (20130101) G01N 15/1475 (20130101) Original (OR) Class G01N 15/1484 (20130101) G01N 2015/1006 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220011270 | Arvanitis et al. |
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FUNDED BY |
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APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
ASSIGNEE(S) | |
INVENTOR(S) | Costas Arvanitis (Atlanta, Georgia); Arpit Patel (Atlanta, Georgia); Scott Joseph Schoen, Jr. (Atlanta, Georgia); Zhigen Zhao (Atlanta, Georgia) |
ABSTRACT | This disclosure describes systems and methods for ultrasound imaging and targeting. In one example, the systems and methods improve targeting and imaging through a heterogenous medium by using the angular spectrum approach (ASA) alone or in combination with passive acoustic mapping (PAM). In another example, the systems and methods improve the ultrasound imaging of vessels using microbubbles. The imaging of the vessels is also aided by the ASA and PAM. A closed loop controller is described that adjusts the ultrasound pressure provided to a region of interest to a desired pressure based at least in part on the harmonic, ultra-harmonic, sub-harmonic, or broadband frequency ranges for the microbubbles. |
FILED | Thursday, November 07, 2019 |
APPL NO | 17/291504 |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/221 (20130101) G01N 29/348 (20130101) G01N 29/0654 (20130101) Original (OR) Class G01N 2291/102 (20130101) G01N 2291/02475 (20130101) G01N 2291/02483 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220011296 | Ligon et al. |
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FUNDED BY |
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APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Keith Ligon (Brookline, Massachusetts); Seth William Malinowski (Boston, Massachusetts); Scott R. Manalis (Cambridge, Massachusetts); Selim Olcum (Cambridge, Massachusetts); Robert J. Kimmerling (Cambridge, Massachusetts); Nicholas L. Calistri (New Fairfield, Connecticut); David Weinstock (Jamaica Plain, Massachusetts); Mark Murakami (Cambridge, Massachusetts); Mark M. Stevens (Seattle, Washington) |
ABSTRACT | Aspects of the application relate to methods and systems for evaluating treatment response by measuring treatment-induced changes at the single cell level. The disclosure provides methods for isolating single cells that are primary cancer cells, including primary cancer cells from solid tumors, and detecting in minutes to hours from their removal from the body the response of such cells to anti-cancer agents such as radiation, small molecules, biologies, DNA damaging agents and the like. |
FILED | Thursday, November 14, 2019 |
APPL NO | 17/293890 |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5017 (20130101) Original (OR) Class G01N 33/5085 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220011304 | Hu et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF NOTRE DAME DU LAC (Notre Dame, Indiana) |
ASSIGNEE(S) | |
INVENTOR(S) | Jiayun Hu (Notre Dame, Indiana); Paul W. Bohn (Notre Dame, Indiana); Marvin J. Miller (South Bend, Indiana); Manuka Ghosh (Granger, Indiana) |
ABSTRACT | Described is a biosensor for detection of analytes and methods of using the same for detecting bacterial infection in a subject. The biosensor comprises an array of gold nanoparticles, biotinylated polyethylene glycol thiol, polyethylene glycol thiol, at least one neutravidin molecule, and at least one affinity reagent immobilized on a surface of the at least one neutravidin molecule. The affinity reagent may be an aptamer or a siderophore. The biosensors demonstrate extraordinary selectively and sensitivity for rapid detection of whole-cell bacteria. |
FILED | Thursday, December 20, 2018 |
APPL NO | 17/297385 |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) C12N 2310/16 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101) G01N 33/54373 (20130101) Original (OR) Class G01N 33/56911 (20130101) G01N 2333/21 (20130101) G01N 2333/22 (20130101) G01N 2800/26 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220011325 | Krishnan et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
ASSIGNEE(S) | |
INVENTOR(S) | Yamuna Krishnan (Chicago, Illinois); Kasturi Chakraborty (Chicago, Illinois); Ka Ho Leung (Chicago, Illinois); Anand Saminathan (Chicago, Illinois) |
ABSTRACT | This disclosure relates to methods for determining pH and also calcium (Ca2+) concentration or chloride (Cl−) concentration in biological samples. More particularly, this disclosure relates to methods capable of simultaneously determining pH and Ca2+ concentration, or pH and Cl− concentration using nucleic acid complexes. |
FILED | Monday, December 02, 2019 |
APPL NO | 17/295704 |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/84 (20130101) Original (OR) Class G01N 33/582 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220011386 | Knappe et al. |
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FUNDED BY |
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APPLICANT(S) | Yoshio OKADA (Denver, Colorado); The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
ASSIGNEE(S) | |
INVENTOR(S) | Svenja Knappe (Boulder, Colorado); Yoshio Okada (Brookline, Massachusetts); Sean Krzyzewski (Boulder, Colorado) |
ABSTRACT | Various embodiments of the present technology relate generally to the field of imaging the spatial distribution of magnetic field of biologic and non-biologic materials that may change over time and more particularly to the apparatus and methods for making such a static or dynamic spatial imaging of magnetic field distributions. Some embodiments provide for apparatus and methods for a novel magnetographic camera which enables a unique ability to determine the spatial distribution of magnetic field in a biological or non-biological sample with high spatial and temporal resolutions and high sensitivity. The use of these embodiments will greatly expand the applications of OPM-based cameras in medicine, science and industry. |
FILED | Thursday, November 21, 2019 |
APPL NO | 17/296179 |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/26 (20130101) Original (OR) Class G01R 33/246 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220012875 | Arnaout |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Rima Arnaout (San Francisco, California) |
ABSTRACT | Systems and methods for medical image diagnoses in accordance with embodiments of the invention are illustrated. One embodiment includes a method for evaluating multimedia content. The method includes steps for receiving multimedia content and identifying a set of one or more image frames for each of several target views from the received multimedia content. For each target view, the method includes steps for evaluating the corresponding set of image frames to generate an intermediate result. The method includes steps for determining a composite result based on the intermediate results for each of the several target views. |
FILED | Wednesday, September 18, 2019 |
APPL NO | 17/281883 |
CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/628 (20130101) G06K 9/6262 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 7/13 (20170101) G06T 2207/10016 (20130101) G06T 2207/20132 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220012902 | Madabhushi et al. |
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FUNDED BY |
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APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
ASSIGNEE(S) | |
INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Jacob Antunes (Cincinnati, Ohio); Zhouping Wei (Cleveland, Ohio); Pallavi Tiwari (Wexford, Pennsylvania); Satish E. Viswanath (Pepper Pike, Ohio); Charlems Alvarez Jimenez (Bogotá, Colombia) |
ABSTRACT | The present disclosure, in some embodiments, relates to a non-transitory computer-readable medium storing computer-executable instructions. The computer readable medium is configured to cause a processor to access an image volume of a rectum comprising a rectal tumor. A forward mapping is generated based on non-rigidly registering a healthy rectal atlas to the image volume. The forward mapping is inverted to generate an inverse mapping from the image volume to the healthy rectal atlas. Based on the inverse mapping, a plurality of deformation vectors, associated with a deformation within a rectal wall of the rectum, are determined. Magnitude based deformation features and orientation based deformation features are computed from the plurality of deformation vectors. One or more of the magnitude based deformation features and one or more of the orientation based deformation features are utilized to determine a response of a patient to a chemoradiation treatment. |
FILED | Wednesday, September 22, 2021 |
APPL NO | 17/481625 |
CURRENT CPC | Image Data Processing or Generation, in General G06T 7/33 (20170101) Original (OR) Class G06T 7/38 (20170101) G06T 2207/10088 (20130101) G06T 2207/30096 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/40 (20180101) G16H 50/70 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
US 20220007819 | O'Brien |
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FUNDED BY |
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APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
ASSIGNEE(S) | |
INVENTOR(S) | Justin O'Brien (Huber Heights, Ohio) |
ABSTRACT | Personal hydration systems with cooling and/or warming capability, and the components thereof are disclosed. The personal hydration systems may include a liquid transport system for transporting cooling or heating fluid between a reservoir and a pad, which pad is configured for wearing adjacent to a wearer's body. A pump is provided for pumping the liquid through the system. A drinking tube is connected to the system for removing liquid from the system. Liquid can be removed from the system for drinking by sucking on the end of the drinking tube. A check valve is used to bypass the pump so the user will not have to suck the liquid through the pump. Alternatively, liquid can be removed by spraying the liquid out of the drinking tube using the power of the pump. |
FILED | Friday, April 16, 2021 |
APPL NO | 17/232183 |
CURRENT CPC | Travelling or Camp Equipment: Sacks or Packs Carried on the Body A45F 3/20 (20130101) Original (OR) Class A45F 2003/166 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008001 | Argenta et al. |
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FUNDED BY |
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APPLICANT(S) | Applied Research Associates, Inc. (Albuquerque, New Mexico) |
ASSIGNEE(S) | |
INVENTOR(S) | Christopher Argenta (Albuquerque, New Mexico); Aaron Williams (Albuquerque, New Mexico); Greg Foderaro (Albuquerque, New Mexico); Thomas Paniagua (Albuquerque, New Mexico) |
ABSTRACT | A system and method of generating an enhanced Lund and Browder chart and total body surface area burn score is described herein. In some embodiments, a plurality of images is obtained from of a patient using a camera system. The images may be taken by aligning the patient's body with pose templates presented on a display of the camera system. The non-skin portions of the images may be removed, and skin analysis performed on the skin portion to determine burn location, coverage, and depth. Further, landmarks may be detected in the images to morph and align the images with the pose templates to obtain standard poses. The plurality of images may be combined and presented in two-dimensional and three-dimensional models with labels and the total surface area burn score. |
FILED | Tuesday, July 07, 2020 |
APPL NO | 16/922598 |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0013 (20130101) A61B 5/0075 (20130101) A61B 5/0077 (20130101) A61B 5/445 (20130101) Original (OR) Class A61B 5/743 (20130101) A61B 5/744 (20130101) A61B 5/6898 (20130101) A61B 5/7264 (20130101) A61B 5/7282 (20130101) A61B 2576/02 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/52 (20130101) G06K 9/00671 (20130101) G06K 9/2018 (20130101) G06K 9/4604 (20130101) G06K 2209/05 (20130101) Image Data Processing or Generation, in General G06T 11/206 (20130101) G06T 19/20 (20130101) G06T 2219/2016 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008346 | Wilson et al. |
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FUNDED BY |
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APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
ASSIGNEE(S) | |
INVENTOR(S) | John T. Wilson (Nashville, Tennessee); Daniel Shae (Nashville, Tennessee); Dinh Chuong Nguyen (Phu Nhuan District, Ho Chi Minh, Viet Nam) |
ABSTRACT | A graft copolymer and a method of delivering an active agent to a subject are provided. The graft copolymer includes a polymer backbone, a hydrophilic segment grafted to the polymer backbone, a pH-responsive segment grafted to the polymer backbone, and an endosomal disruption segment grafted to the polymer backbone. The method of delivering an active agent to a subject includes encapsulating the active agent with the graft copolymer and administering the encapsulated active agent to the subject. |
FILED | Wednesday, October 30, 2019 |
APPL NO | 17/290618 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5026 (20130101) Original (OR) Class Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 290/062 (20130101) C08F 2438/03 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008383 | Yee et al. |
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FUNDED BY |
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APPLICANT(S) | Amy Yee (Brookline, Massachusetts); Eric Paulson (Brookline, Massachusetts) |
ASSIGNEE(S) | |
INVENTOR(S) | Amy Yee (Brookline, Massachusetts); Eric Paulson (Brookline, Massachusetts) |
ABSTRACT | The present invention relates to compositions and methods of treating a subject having cancer by stimulating the subject's immune system and/or enhancing immunotherapies. Specifically, the present invention relates to methods of treating a subject by administering (1) a catechin ester or a derivative or metabolite thereof (e.g., EGCG) and (2) a nucleoside analogue (e.g., DAC), in combination with a checkpoint inhibitor or T-cell therapy. |
FILED | Wednesday, November 13, 2019 |
APPL NO | 17/293648 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/353 (20130101) Original (OR) Class A61K 31/7068 (20130101) Peptides C07K 16/2818 (20130101) C07K 16/2827 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008918 | ISMAGILOV et al. |
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FUNDED BY |
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APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Rustem F. ISMAGILOV (Altadena, California); Travis S. SCHLAPPI (Pasadena, California); Stephanie E. MCCALLA (Bozeman, Montana); Nathan G. SCHOEPP (Pasadena, California) |
ABSTRACT | Methods and devices for detecting a low concentration analyte in a sample are provided herein. The methods include flowing a sample through a porous membrane coated with a capture matrix to capture the low concentration analyte. The methods also can include detecting the captured analyte, such as by performing in-situ amplification of the analyte. |
FILED | Friday, July 07, 2017 |
APPL NO | 16/316193 |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5023 (20130101) B01L 3/502715 (20130101) Original (OR) Class B01L 7/52 (20130101) B01L 2300/069 (20130101) B01L 2300/163 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220009199 | Smith et al. |
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FUNDED BY |
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APPLICANT(S) | SWIFT TEXTILE METALIZING LLC (Bloomfield, Connecticut) |
ASSIGNEE(S) | |
INVENTOR(S) | Alexander T. Smith (Knoxville, Tennessee); Jared DG Butlin (Longmeadow, Massachusetts) |
ABSTRACT | A composite structure is provided that includes a polymer layer and an auxetic material layer disposed within or partially within the polymer layer. The auxetic material layer provides increased conductivity and elastomeric reinforcement to the polymer layer. |
FILED | Wednesday, June 16, 2021 |
APPL NO | 17/349762 |
CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/026 (20130101) B32B 7/12 (20130101) B32B 7/022 (20190101) Original (OR) Class B32B 7/025 (20190101) B32B 27/12 (20130101) B32B 27/20 (20130101) B32B 2255/02 (20130101) B32B 2255/26 (20130101) B32B 2262/02 (20130101) B32B 2307/202 (20130101) B32B 2307/212 (20130101) B32B 2307/706 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220009300 | Benedict et al. |
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FUNDED BY |
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APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
ASSIGNEE(S) | The Texas A and M University System (College Station, Texas) |
INVENTOR(S) | Moble Benedict (College Station, Texas); Sean M. McHugh (San Jose, California); Chase B. Wiley (Keller, Texas); Ramsay A. Ramsey (College Station, Texas); Adam Kellen (San Antonio, Texas); Yin Lu Young (Ann Arbor, Michigan) |
ABSTRACT | An amphibious vehicle for traversing land and bodies of water includes a chassis, and a cycloidal propeller coupled to the chassis and which includes a plurality of cycloidal propeller blades rotatably coupled to the chassis and each extending parallel a rotational axis of the cycloidal propeller, and an extension/retraction system configured to extend the plurality of cycloidal propeller blades away from the chassis and to retract the plurality of cycloidal propeller blades towards the chassis. |
FILED | Friday, May 14, 2021 |
APPL NO | 17/321048 |
CURRENT CPC | Vehicles for Use Both on Rail and on Road; Amphibious or Like Vehicles; Convertible Vehicles B60F 3/0007 (20130101) Original (OR) Class Marine Propulsion or Steering B63H 1/06 (20130101) B63H 3/00 (20130101) B63H 21/17 (20130101) B63H 25/42 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220009532 | Notomista et al. |
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FUNDED BY |
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APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
ASSIGNEE(S) | |
INVENTOR(S) | Gennaro Notomista (Atlanta, Georgia); Magnus B. Egerstedt (Atlanta, Georgia); Yousef A. Emam (Atlanta, Georgia) |
ABSTRACT | An exemplary embodiment of the present disclosure provides a robot comprising a body, a processor, and a memory. The memory further comprising instructions that, when executed by the processor cause the body to engage a first wire to support the robot from the first wire, traverse the first wire, engage a second wire simultaneously while engaging the first wire, the second wire branching from the first wire, then after engaging the second wire, disengage the first wire and traverse the second wire. |
FILED | Tuesday, February 16, 2021 |
APPL NO | 17/176927 |
CURRENT CPC | Railway Systems; Equipment Therefor Not Otherwise Provided for B61B 3/02 (20130101) Guiding Railway Traffic; Ensuring the Safety of Railway Traffic B61L 3/006 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220009651 | Lampazzi et al. |
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FUNDED BY |
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APPLICANT(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
ASSIGNEE(S) | |
INVENTOR(S) | Margaret MacIsaac Lampazzi (Newtown, Connecticut); Carl John Pankok, JR. (Philadelphia, Pennsylvania); Igor Cherepinsky (Sandy Hook, Connecticut) |
ABSTRACT | A technique relates to interactive aircraft operation. An interactive electronic checklist is selected from a plurality of interactive electronic checklists, the interactive electronic checklists each comprising checklist tasks. It is perceived that one or more of the checklist tasks in the interactive electronic checklist is executable by an autonomous system. The one or more of the checklist tasks is performed using the autonomous system, an operator being designated to perform any other ones of the checklist tasks. |
FILED | Wednesday, July 08, 2020 |
APPL NO | 16/923143 |
CURRENT CPC | Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 5/60 (20170101) Original (OR) Class Electric Digital Data Processing G06F 3/0482 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010055 | Nuckolls et al. |
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FUNDED BY |
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APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
INVENTOR(S) | Colin Nuckolls (New York, New York); Xavier Roy (New York, New York); Jake Carter Russell (New York, New York); Samuel R. Peurifoy (New York, New York) |
ABSTRACT | The present disclosure provides organic compounds having pseudocapacitive performance and methods of preparing said compounds. The organic compounds can include perylene diamine (PDI) subunits and hexaazatrinaphthylene (HATN) subunits. |
FILED | Friday, February 19, 2021 |
APPL NO | 17/180046 |
CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/122 (20130101) Original (OR) Class C08G 2261/12 (20130101) C08G 2261/228 (20130101) C08G 2261/411 (20130101) C08G 2261/3241 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/48 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010165 | Lukus et al. |
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FUNDED BY |
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APPLICANT(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio) |
ASSIGNEE(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio) |
INVENTOR(S) | Peter Alan Lukus (Sarver, Pennsylvania); Michael J. Pawlik (Glenshaw, Pennsylvania); Silvia Bezer (Gibsonia, Pennsylvania); Steven R. Zawacky (Cranberry Township, Pennsylvania); Diane Jean Schillinger (Allison Park, Pennsylvania); Samuel Logan Esarey (Allison Park, Pennsylvania) |
ABSTRACT | The present invention is directed to an aqueous curable film-forming composition comprising: (a) a film-forming component comprising an aliphatic di- or higher functional polyisocyanate; and (b) a catalyst additive comprising: (i) a catalytic organic compound comprising iron (II) and optionally tin; and (ii) a beta-diketone. The present invention is further directed to a method of controlling the rate of cure of an aqueous curable film-forming composition. The method comprises adding to the aqueous curable film-forming composition the catalyst additive described above; the aqueous curable film-forming composition comprises a film-forming component comprising an aliphatic di- or higher functional polyisocyanate. The present invention is additionally directed to a coated article comprising a cured coating layer applied on at least one surface of a substrate to form a coated substrate; wherein the cured coating layer is deposited from the aqueous curable film-forming composition described above. |
FILED | Thursday, November 08, 2018 |
APPL NO | 17/292413 |
CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/222 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/002 (20130101) C09D 7/20 (20180101) C09D 175/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010228 | Collett et al. |
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FUNDED BY |
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APPLICANT(S) | METSS Corp. (Westerville, Ohio) |
ASSIGNEE(S) | METSS Corp. (Westerville, Ohio) |
INVENTOR(S) | Brian R. Collett (Columbus, Ohio); Angela Theys (Kansas City, Missouri); Michelle Docter (Columbus, Ohio); Joseph Sanders (Powell, Ohio); Kenneth J. Heater (Delaware, Ohio) |
ABSTRACT | Lubricating compositions are described, the lubricating compositions comprising a base oil component and an additive component, wherein the additive component comprises a non-silicone anti-foaming agent. |
FILED | Tuesday, July 06, 2021 |
APPL NO | 17/367964 |
CURRENT CPC | Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition C10M 101/00 (20130101) C10M 107/10 (20130101) C10M 129/34 (20130101) C10M 133/12 (20130101) C10M 133/44 (20130101) C10M 137/04 (20130101) C10M 145/14 (20130101) Original (OR) Class C10M 169/044 (20130101) C10M 2205/0285 (20130101) C10M 2207/123 (20130101) C10M 2209/084 (20130101) C10M 2215/06 (20130101) C10M 2215/223 (20130101) C10M 2223/041 (20130101) Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions C10N 2020/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010269 | Cullen et al. |
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FUNDED BY |
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APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
ASSIGNEE(S) | |
INVENTOR(S) | Daniel Kacy Cullen (Media, Pennsylvania); Suradip Das (Philadelphia, Pennsylvania); Wisberty Gordian-Velez (Philadelphia, Pennsylvania) |
ABSTRACT | In various aspects and embodiments, the present invention provides methods for preparing innervated tissue. In various embodiments the invention further provides innervated tissue generated using the methods described herein. In various embodiments the inclusion of optogenetically transducible TENGs or Micro-TENNs in the innervated tissue allows the modulation of tissue or organs by using light to stimulate the optogenetically transducible TENGs or Micro-TENNs. |
FILED | Friday, November 08, 2019 |
APPL NO | 17/291869 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/34 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) Original (OR) Class C12N 5/0619 (20130101) C12N 5/0633 (20130101) C12N 5/0648 (20130101) C12N 5/0657 (20130101) C12N 5/0658 (20130101) C12N 5/0677 (20130101) C12N 5/0679 (20130101) C12N 5/0685 (20130101) C12N 2502/081 (20130101) C12N 2513/00 (20130101) C12N 2533/76 (20130101) C12N 2533/80 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010391 | Lloyd et al. |
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FUNDED BY |
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APPLICANT(S) | U.S. Army Combat Capabilities Development Command, Army Research Labortary (Adelphi, Maryland) |
ASSIGNEE(S) | |
INVENTOR(S) | Jeffrey T. Lloyd (Aberdeen, Maryland); Phillip A. Jannotti (Baltimore, Maryland); Daniel J. Magagnosc (Baltimore, Maryland) |
ABSTRACT | A metal structure includes an alloy material containing structural deformation twins embedded during a manufacturing process of the alloy material along defined directions, a defined deformation sequence, and defined strain levels. The embedded structural deformation twins mitigate failure and fracture in the alloy material. |
FILED | Friday, July 10, 2020 |
APPL NO | 16/925697 |
CURRENT CPC | Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 7/10 (20130101) Original (OR) Class Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/06 (20130101) C22F 1/183 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010981 | Narayanan et al. |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Vinod Narayanan (Davis, California); Erfan Rasouli (Davis, California) |
ABSTRACT | The disclosed embodiments relate to a system that provides a polymer heat exchanger with internal microscale flow passages. The system includes a set of plates comprised of a polymer that includes internal microscale flow passages, which are configured to carry a liquid. The set of plates is organized into a stack, wherein consecutive plates in the stack are separated by fins to form intervening air passages. The system includes a liquid flow pathway, which flows from a liquid inlet, through the internal microscale flow passages in the stack of plates, to a liquid outlet. It also includes an airflow pathway, which flows from an airflow inlet, through the intervening air passages between the consecutive plates in the stack of plates, to an airflow outlet. The liquid flow pathway flows in a direction opposite to a direction of the airflow pathway to provide a counterflow design that optimizes heat transfer between the liquid flow pathway and the airflow pathway. |
FILED | Wednesday, January 13, 2021 |
APPL NO | 17/148359 |
CURRENT CPC | Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 1/0067 (20190201) Original (OR) Class F24F 1/00077 (20190201) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 9/002 (20130101) F25B 30/02 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 3/022 (20130101) F28F 3/048 (20130101) F28F 2250/106 (20130101) F28F 2255/143 (20130101) F28F 2260/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220011057 | Brown et al. |
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APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
ASSIGNEE(S) | |
INVENTOR(S) | Robert F. Brown (Summerland Key, Florida); Gregory M. Smith (Alexandria, Virginia); Christopher Brady (Bradenton, Florida) |
ABSTRACT | A cooling system for a cold spray nozzle or a thermal spray barrel and a fabrication method thereof are provided. The cooling system includes a sleeve with cooling fins that encapsulate a spray nozzle or barrel to enable heat transfer from the nozzle or barrel to the fins and then to the external ambient environment. The sleeve may optionally include one or more channels with cooling tubes to enable enhanced cooling with a cooling medium flowing through the tubes and across the fins. |
FILED | Tuesday, June 22, 2021 |
APPL NO | 17/354780 |
CURRENT CPC | Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 1/26 (20130101) Original (OR) Class Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 21/24 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220011089 | Garan et al. |
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FUNDED BY |
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APPLICANT(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (, None) |
INVENTOR(S) | Jacob D. Garan (Honolulu, Hawaii); Mark S. Branham (Oro Valley, Arizona); Christopher E. Saxer (Southport, North Carolina) |
ABSTRACT | A splitting and recombining optical component with an increased field of view while maintaining or only minimally increasing the space requirements therefor is provided. Further, the combination of the changes in physical geometry and refractive index of the beam splitting and recombining optical device can increase the field of view of a system while maintaining, or even reducing, the mass of the system in which the present beam splitting and recombining optic may be utilized |
FILED | Thursday, July 09, 2020 |
APPL NO | 16/924876 |
CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02022 (20130101) Original (OR) Class G01B 9/02068 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220011161 | Han et al. |
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FUNDED BY |
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APPLICANT(S) | SAMSUNG ELECTRONICS CO., LTD. (Suwon-si, South Korea); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
ASSIGNEE(S) | SAMSUNG ELECTRONICS CO., LTD. (Suwon-si, South Korea); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
INVENTOR(S) | Seunghoon Han (Seoul, South Korea); Amir Arbabi (Pasadena, California); Andrei Faraon (Pasadena, California); Ehsan Arbabi (Pasadena, California) |
ABSTRACT | A spectrometer includes a transparent substrate including a first surface and a second surface that face each other and are substantially parallel to each other; a slit provided on the first surface and through which light is incident onto the transparent substrate; a spectrum optical system including metasurface including a plurality of nanostructures that are two-dimensionally arranged and satisfy a sub-wavelength scattering condition, wherein the metasurface includes a focusing metasurface which includes first nanostructures of the plurality of nanostructures, and is configured to reflect, disperse, and focus the light incident thereon through the slit, at different angles based on respective wavelengths; and a sensor configured to receive the light from the focusing metasurface. When L is a total length of an optical path from the slit to the sensor and D is a thickness of the transparent substrate, L and D satisfy the following inequality: L/D>3. |
FILED | Monday, September 27, 2021 |
APPL NO | 17/486326 |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/0205 (20130101) G01J 3/0208 (20130101) Original (OR) Class G01J 3/0224 (20130101) G01J 3/0256 (20130101) G01J 3/0259 (20130101) G01J 3/447 (20130101) G01J 3/2803 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220011163 | Shi et al. |
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FUNDED BY |
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APPLICANT(S) | University of South Florida (Tampa, Florida) |
ASSIGNEE(S) | The University of Rochester (Rochester, New York); University of South Florida (Tampa, Florida) |
INVENTOR(S) | Zhimin Shi (Tampa, Florida); Darrick Hay (Brandon, Florida); Ziyi Zhu (Tampa, Florida); Yiyu Zhou (Rochester, New York); Robert W. Boyd (Webster, New York) |
ABSTRACT | An apparatus measures the transverse profile of vectorial optical field beams, including both the phase and the polarization spatial profile. The apparatus contains a polarization separation module, a weak perturbation module, and a detection module. Characterizing the transverse profile of vector fields provides an optical metrology tool for both fundamental studies of vectorial optical fields and a wide spectrum of applications, including microscopy, surveillance, imaging, communication, material processing, and laser trapping. |
FILED | Monday, July 19, 2021 |
APPL NO | 17/379507 |
CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 4/04 (20130101) Original (OR) Class G01J 11/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220011300 | Ramsey et al. |
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FUNDED BY |
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APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hil, North Carolina) |
ASSIGNEE(S) | |
INVENTOR(S) | John Michael Ramsey (Chapel Hill, North Carolina); William Hampton Henley (Chapel Hill, North Carolina); Thomas Linz (Chapel Hill, North Carolina) |
ABSTRACT | Decoding methods are provided for identifying populations in assays, particularly multiplexing assays and those associated with fluidic devices. |
FILED | Thursday, April 29, 2021 |
APPL NO | 17/244257 |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/542 (20130101) Original (OR) Class G01N 33/54313 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220011363 | Rupper et al. |
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FUNDED BY |
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APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
ASSIGNEE(S) | |
INVENTOR(S) | Greg Rupper (Silver Spring, Maryland); John Suarez (Brooklyn, New York); Sergey Rudin (Dayton, Maryland); Meredith Reed (Perry Hall, Maryland); Michael Shur (Latham, New York) |
ABSTRACT | Various embodiments are described that relate to failure determination for an integrated circuit. An integrated circuit can be tested to determine if the integrated circuit is functioning properly. The integrated circuit can be subjected to a specific radiation such that the integrated circuit produces a response. This response can be compared against an expected response to determine if the response matches the expected response. If the response does not match the expected response, then the integrated circuit fails the test. If the response matches the expected response, then the integrated circuit passes the test. |
FILED | Tuesday, December 15, 2020 |
APPL NO | 17/121851 |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/311 (20130101) Original (OR) Class G01R 31/2656 (20130101) G01R 31/2815 (20130101) G01R 31/318533 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220011383 | Barry et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | John F. Barry (Arlington, Massachusetts); Reed Anderson Irion (Belmont, Massachusetts); Jessica Kedziora (Shirley, Massachusetts); Matthew Steinecker (Medford, Massachusetts); Daniel K. Freeman (Reading, Massachusetts); Danielle A. Braje (Winchester, Massachusetts) |
ABSTRACT | Ferrimagnetic oscillator magnetometers do not use lasers to stimulate fluorescence emission from defect centers in solid-state hosts (e.g., nitrogen vacancies in diamonds). Instead, in a ferrimagnetic oscillator magnetometer, the applied magnetic field shifts the resonance of entangled electronic spins in a ferrimagnetic crystal. These spins are entangled and can have an ensemble resonance linewidth of approximately 370 kHz to 10 MHz. The resonance shift produces microwave sidebands with amplitudes proportional to the magnetic field strength at frequencies proportional to the magnetic field oscillation frequency. These sidebands can be coherently averaged, digitized, and coherently processed, yielding magnetic field measurements with sensitivities possibly approaching the spin projection limit of 1 attotesla/√{square root over (Hz)}. The encoding of magnetic signals in frequency rather than amplitude relaxes or removes otherwise stringent requires on the digitizer. |
FILED | Wednesday, May 12, 2021 |
APPL NO | 17/317983 |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/02 (20130101) Original (OR) Class Electric Digital Data Processing G06F 3/046 (20130101) Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 15/006 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220011512 | Ramachandran et al. |
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APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
ASSIGNEE(S) | |
INVENTOR(S) | Siddharth Ramachandran (Boston, Massachusetts); Zelin Ma (Boston, Massachusetts) |
ABSTRACT | An optical fiber system exploits a principle of topological confinement for guided higher-order modes, in contrast to more conventional total-internal-reflection (TIR) confinement. The optical fiber has a geometry and index profile defining a cutoff wavelength for a predetermined L-mode of optical signal propagation in the optical fiber, where L is azimuthal mode index. An optical source subsystem is coupled to the optical fiber to establish an optical signal propagating in the optical fiber, wherein the optical signal has the predetermined L-mode and a wavelength being either (1) at least 15% above the cutoff wavelength such that the optical beam propagates as a topologically confined mode, or (2) sufficiently above the cutoff wavelength that, based on the L-mode of the optical beam, the optical beam propagates as a topologically confined mode having propagation loss less than 3 dB/meter. |
FILED | Sunday, May 09, 2021 |
APPL NO | 17/315314 |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/14 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220011646 | Semmlinger et al. |
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FUNDED BY |
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APPLICANT(S) | William Marsh Rice University (Houston, Texas); Academia Sinica (Taipei, Taiwan) |
ASSIGNEE(S) | William Marsh Rice University (Houston, Texas); Academia Sinica (Taipei, Taiwan) |
INVENTOR(S) | Michael Semmlinger (Houston, Texas); Ming Lun Tseng (Taipei, Taiwan); Jian Yang (Houston, Texas); Ming Zhang (Houston, Texas); Din Ping Tsai (Taipei, Taiwan); Liangliang Dong (Houston, Texas); Arash Ahmadivand (Houston, Texas); Peter Nordlander (Houston, Texas); Nancy Jean Halas (Houston, Texas) |
ABSTRACT | A harmonic light-generating metasurface includes a base substrate and a plurality of structures, that include nonlinear material, that are disposed in a pattern on a surface of the base substrate. Each structure of the plurality of structures individually supports a magnetic dipole mode. An electromagnetic field enhancement of the magnetic dipole mode induces generation of a harmonic signal by the plurality of structures. Alternatively, a harmonic light-generating metasurface, includes a base substrate, a supporting substrate that includes a nonlinear material, and a plurality of paired structures disposed in a pattern on a surface of the supporting substrate. Each paired structure, of the plurality of paired structures, collectively supports a toroidal dipole mode. An electromagnetic field enhancement of the toroidal dipole mode penetrates the supporting substrate to induce generation of a harmonic signal by the supporting substrate. |
FILED | Tuesday, October 01, 2019 |
APPL NO | 17/281814 |
CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/37 (20130101) Original (OR) Class G02F 1/354 (20210101) G02F 2202/30 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220011664 | Talapin et al. |
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APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
ASSIGNEE(S) | |
INVENTOR(S) | Dmitri V. Talapin (La Grange Park, Illinois); Yuanyuan Wang (Nanjing, China PRC); Jia-Ahn Pan (Chicago, Illinois); Haoqi Wu (Chicago, Illinois) |
ABSTRACT | Ligand-capped inorganic particles, dispersions of the ligand-capped inorganic particles, and films composed of the ligand-capped inorganic particles are provided. Also provided are methods of patterning the films and electronic, photonic, and optoelectronic devices that incorporate the films. The ligands include bifunctional ligands and two-component ligand systems that include a photosensitive group, cation, or molecule. |
FILED | Friday, October 11, 2019 |
APPL NO | 17/283457 |
CURRENT CPC | Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/008 (20130101) G03F 7/20 (20130101) G03F 7/32 (20130101) G03F 7/0045 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220012060 | Fok et al. |
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FUNDED BY |
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APPLICANT(S) | Femtosense, Inc. (Palo Alto, California) |
ASSIGNEE(S) | Femtosense, Inc. (Palo Alto, California) |
INVENTOR(S) | Sam Brian Fok (San Leandro, California); Alexander Smith Neckar (Redwood City, California) |
ABSTRACT | Systems, apparatus, and methods for thread-based scheduling within a multicore processor. Neural networking uses a network of connected nodes (aka neurons) to loosely model the neuro-biological functionality found in the human brain. Various embodiments of the present disclosure use thread dependency graphs analysis to decouple scheduling across many distributed cores. Rather than using thread dependency graphs to generate a sequential ordering for a centralized scheduler, the individual thread dependencies define a count value for each thread at compile-time. Threads and their thread dependency count are distributed to each core at run-time. Thereafter, each core can dynamically determine which threads to execute based on fulfilled thread dependencies without requiring a centralized scheduler. |
FILED | Monday, July 05, 2021 |
APPL NO | 17/367521 |
CURRENT CPC | Electric Digital Data Processing G06F 9/3802 (20130101) G06F 9/3818 (20130101) G06F 9/3838 (20130101) Original (OR) Class G06F 11/3024 (20130101) G06F 11/3433 (20130101) Computer Systems Based on Specific Computational Models G06N 3/063 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220012213 | Ganti et al. |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | |
INVENTOR(S) | Raghu Kiran Ganti (Elmsford, New York); Shen Li (Urbana, Illinois); Mudhakar Srivatsa (White Plains, New York) |
ABSTRACT | A spatial-temporal storage method, system, and non-transitory computer readable medium include dynamically managing a plurality of region servers for querying spatiotemporal data in noSQL databases. |
FILED | Thursday, September 23, 2021 |
APPL NO | 17/482651 |
CURRENT CPC | Electric Digital Data Processing G06F 16/275 (20190101) G06F 16/284 (20190101) G06F 16/1844 (20190101) Original (OR) Class G06F 16/2452 (20190101) G06F 16/2453 (20190101) G06F 16/2477 (20190101) G06F 16/9537 (20190101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220012575 | Fok et al. |
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FUNDED BY |
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APPLICANT(S) | Femtosense, Inc. (Palo Alto, California) |
ASSIGNEE(S) | Femtosense, Inc. (Palo Alto, California) |
INVENTOR(S) | Sam Brian Fok (San Leandro, California); Alexander Smith Neckar (Redwood City, California); Scott Henry Reid (Palo Alto, California) |
ABSTRACT | Methods and apparatus for localized processing within multicore neural networks. Unlike existing solutions that rely on commodity software and hardware to perform “brute force” large scale neural network processing the various techniques described herein map and partition a neural network into the hardware limitations of a target platform. Specifically, the various implementations described herein synergistically leverage localization, sparsity, and distributed scheduling, to enable neural network processing within embedded hardware applications. As described herein, hardware-aware mapping/partitioning enhances neural network performance by e.g., avoiding pin-limited memory accesses, processing data in compressed formats/skipping unnecessary operations, and decoupling scheduling between cores. |
FILED | Monday, July 05, 2021 |
APPL NO | 17/367512 |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/063 (20130101) Original (OR) Class G06N 3/0454 (20130101) G06N 3/0481 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220012598 | Fok et al. |
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FUNDED BY |
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APPLICANT(S) | Femtosense, Inc. (Palo Alto, California) |
ASSIGNEE(S) | Femtosense, Inc. (Palo Alto, California) |
INVENTOR(S) | Sam Brian Fok (San Leandro, California); Alexander Smith Neckar (Redwood City, California); Manish Shrivastava (Pleasanton, California) |
ABSTRACT | Methods and apparatus for matrix and vector storage and operations are disclosed. Vectors and matrices may be represented differently to further enhance performance of operations. Exemplary embodiments compress sparse neural network data structures based on actual, non-null, connectivity (rather than all possible connections). This greatly reduces storage requirements as well as computational complexity. In some variants, the compression and reduction in complexity is sized to fit within the memory footprint and processing capabilities of a core. The exemplary compression schemes represent sparse matrices with links to compressed column data structures, where each compressed column data structure only stores non-null entries to optimize column-based lookups of non-null entries. Similarly, sparse vector addressing skips nulled entries to optimize for vector-specific non-null multiply-accumulate operations. |
FILED | Monday, July 05, 2021 |
APPL NO | 17/367517 |
CURRENT CPC | Electric Digital Data Processing G06F 16/901 (20190101) G06F 17/16 (20130101) Computer Systems Based on Specific Computational Models G06N 3/10 (20130101) Original (OR) Class Coding; Decoding; Code Conversion in General H03M 7/702 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220012619 | ROQUES-CARMES et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Charles ROQUES-CARMES (Cambridge, Massachusetts); Yichen Shen (Cambridge, Massachusetts); Li JING (Cambridge, Massachusetts); Tena DUBCEK (Cambridge, Massachusetts); Scott A. SKIRLO (Boston, Massachusetts); Hengameh BAGHERIANLEMRASKI (Cambridge, Massachusetts); Marin SOLJACIC (Belmont, Massachusetts) |
ABSTRACT | A photonic parallel network can be used to sample combinatorially hard distributions of Ising problems. The photonic parallel network, also called a photonic processor, finds the ground state of a general Ising problem and can probe critical behaviors of universality classes and their critical exponents. In addition to the attractive features of photonic networks—passivity, parallelization, high-speed and low-power—the photonic processor exploits dynamic noise that occurs during the detection process to find ground states more efficiently. |
FILED | Monday, April 26, 2021 |
APPL NO | 17/239830 |
CURRENT CPC | Electric Digital Data Processing G06F 17/16 (20130101) Computer Systems Based on Specific Computational Models G06N 3/084 (20130101) G06N 3/0445 (20130101) G06N 3/0454 (20130101) G06N 3/0472 (20130101) G06N 3/0675 (20130101) G06N 7/005 (20130101) G06N 10/00 (20190101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220012646 | RUBENSTEIN et al. |
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FUNDED BY |
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APPLICANT(S) | BROWN UNIVERSITY (, None) |
ASSIGNEE(S) | |
INVENTOR(S) | Brenda RUBENSTEIN (Providence, Rhode Island); Jacob Karl ROSENSTEIN (Providence, Rhode Island); Christopher ARCADIA (Providence, Rhode Island); Shui Ling CHEN (Harrisburg, Pennsylvania); Amanda Doris DOMBROSKI (Cranston, Rhode Island); Joseph D. GEISER (Barrington, Rhode Island); Eamonn KENNEDY (West Warwick, Rhode Island); Eunsuk KIM (Providence, Rhode Island); Kady M. OAKLEY (North Attleboro, Massachusetts); Sherief REDA (Barrington, Rhode Island); Christopher ROSE (Providence, Rhode Island); Jason Kelby SELLO (Tiverton, Rhode Island); Hokchhay TANN (Providence, Rhode Island); Peter WEBER (Barrington, Rhode Island) |
ABSTRACT | The invention provides methods for computing with chemicals by encoding digital data into a plurality of chemicals to obtain a dataset; translating the dataset into a chemical form; reading the data set; querying the dataset by performing an operation to obtain a perceptron; and analyzing the perceptron for identifying chemical structure and/or concentration of at least one of the chemicals, thereby developing a chemical computational language. The invention demonstrates a workflow for representing abstract data in synthetic metabolomes. Also presented are several demonstrations of kilobyte-scale image data sets stored in synthetic metabolomes, recovered at >99% accuracy. |
FILED | Monday, July 19, 2021 |
APPL NO | 17/378988 |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 99/007 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220012902 | Madabhushi et al. |
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FUNDED BY |
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APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
ASSIGNEE(S) | |
INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Jacob Antunes (Cincinnati, Ohio); Zhouping Wei (Cleveland, Ohio); Pallavi Tiwari (Wexford, Pennsylvania); Satish E. Viswanath (Pepper Pike, Ohio); Charlems Alvarez Jimenez (Bogotá, Colombia) |
ABSTRACT | The present disclosure, in some embodiments, relates to a non-transitory computer-readable medium storing computer-executable instructions. The computer readable medium is configured to cause a processor to access an image volume of a rectum comprising a rectal tumor. A forward mapping is generated based on non-rigidly registering a healthy rectal atlas to the image volume. The forward mapping is inverted to generate an inverse mapping from the image volume to the healthy rectal atlas. Based on the inverse mapping, a plurality of deformation vectors, associated with a deformation within a rectal wall of the rectum, are determined. Magnitude based deformation features and orientation based deformation features are computed from the plurality of deformation vectors. One or more of the magnitude based deformation features and one or more of the orientation based deformation features are utilized to determine a response of a patient to a chemoradiation treatment. |
FILED | Wednesday, September 22, 2021 |
APPL NO | 17/481625 |
CURRENT CPC | Image Data Processing or Generation, in General G06T 7/33 (20170101) Original (OR) Class G06T 7/38 (20170101) G06T 2207/10088 (20130101) G06T 2207/30096 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/40 (20180101) G16H 50/70 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220012937 | Lilley et al. |
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FUNDED BY |
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APPLICANT(S) | Cesium GS, Inc. (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | |
INVENTOR(S) | Ian Lilley (Philadelphia, Pennsylvania); Sean Lilley (Philadelphia, Pennsylvania); Patrick Cozzi (Drexel Hill, Pennsylvania) |
ABSTRACT | Systems, methods, devices, and non-transitory media of various embodiments enable rendering of a time-dynamic (4D) volume dataset. Various embodiments may provide a method for responsive and high quality rendering of time-dynamic hierarchical level-of-detail voxel datasets. Various embodiments may provide a prioritization system that balances visual quality and temporal responsiveness even with slow network or filesystem speeds. Various embodiments may provide a compact and efficient storage format for time-dynamic and mixed-resolution voxel rendering on a graphics processing unit (GPU). |
FILED | Friday, July 09, 2021 |
APPL NO | 17/372344 |
CURRENT CPC | Image Data Processing or Generation, in General G06T 15/04 (20130101) G06T 15/005 (20130101) G06T 15/08 (20130101) Original (OR) Class G06T 15/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220013288 | SPANIER et al. |
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FUNDED BY |
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APPLICANT(S) | Jonathan E. SPANIER (Bala Cynwyd, Pennsylvania); Iryna S. GOLOVINA (Philadelphia, Pennsylvania); Aleksandr V. PLOKHIKH (Philadelphia, Pennsylvania); Mattias FALMBIGL (Syosset, New York) |
ASSIGNEE(S) | |
INVENTOR(S) | Jonathan E. SPANIER (Bala Cynwyd, Pennsylvania); Iryna S. GOLOVINA (Philadelphia, Pennsylvania); Aleksandr V. PLOKHIKH (Philadelphia, Pennsylvania); Mattias FALMBIGL (Syosset, New York) |
ABSTRACT | Provided is the dielectric response of atomic layer-deposited and annealed polymorphic BaTiO3 and BaTiO3—Al2O3 bi-layer thin films based on nanocry stalline BaTiO3 containing the perovskite and hexagonal polymorphs. Also provided are BaTiO3 films having tuned Curie temperatures. Further provided are capacitive components, comprising: a plurality of films, the plurality of films comprising: a first grained film component, the first grained film component comprising at least one of SrTiO3, BaTiO3, and (Ba, Sr)TiO3, and the first grained film component being characterized as being at least partially polymorphic crystalline in nature; a second film component contacting the first grained film component, the second film component optionally comprising Al2O3, and the first grained film component optionally defining an average grain size of less than about 10 micrometers. |
FILED | Wednesday, November 13, 2019 |
APPL NO | 17/293575 |
CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 4/008 (20130101) H01G 4/10 (20130101) H01G 4/33 (20130101) H01G 4/306 (20130101) H01G 4/1227 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 28/56 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220013719 | CADY et al. |
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FUNDED BY |
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APPLICANT(S) | The Research Foundation for the State University of New York (Albany, New York); GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (Wright-Patterson AFB, Ohio) |
ASSIGNEE(S) | |
INVENTOR(S) | Nathaniel CADY (Delmar, New York); Karsten BECKMANN (Albany, New York); Joseph VAN NOSTRAND (Rome, New York) |
ABSTRACT | A resistive random access memory (ReRAM) device includes a bottom electrode and a top electrode with a switching layer disposed therebetween. The bottom electrode has a top surface in contact with a bottom surface of the switching layer. The bottom electrode also has first and second sidewalls spaced apart by a first distance where the sidewalls contact the bottom surface of the switching layer. The switching layer has first and second sidewalls spaced apart by a second distance that is larger than the first distance. The top electrode is disposed over the switching layer. The first sidewall of the switching layer overhangs the first sidewall of the bottom electrode by an overhang distance of 5 nanometers or more. The second sidewall of the switching layer overhangs the second sidewall of the bottom electrode by an overhang distance of 5 nanometers or more. |
FILED | Monday, September 23, 2019 |
APPL NO | 17/295920 |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 45/08 (20130101) H01L 45/146 (20130101) H01L 45/1233 (20130101) H01L 45/1253 (20130101) Original (OR) Class H01L 45/1675 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220013977 | Zhou et al. |
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FUNDED BY |
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APPLICANT(S) | Board of Regents, The University of Texas System (UsAustin, Texas) |
ASSIGNEE(S) | |
INVENTOR(S) | Weidong Zhou (Southlake, Texas); Xiaochen Ge (Sugar Land, Texas) |
ABSTRACT | In one embodiment, a nanobeam cavity device includes an elongated waveguide having a central optical cavity, first and second lateral substrates that are positioned on opposed lateral sides of the waveguide, and carrier-injection beams that extend from the first and second lateral substrates to the central optical cavity of the elongated waveguide. |
FILED | Wednesday, July 07, 2021 |
APPL NO | 17/369789 |
CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/11 (20210101) H01S 5/026 (20130101) Original (OR) Class H01S 5/1042 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220014280 | Hutchinson et al. |
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FUNDED BY |
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APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | |
INVENTOR(S) | Meredith N. Hutchinson (Washington, District of Columbia); Jonathan M. Nichols (Crofton, Maryland) |
ABSTRACT | Methods, apparatuses, and systems for removing noise from a received signal. A signal is received, at a controller, that was recorded by a sensor and emitted by a source. The signal includes a signal of interest component and a noise component. The noise component of the signal is sampled, and the sampled noise component of the signal is used to estimate a variance in the noise component. An energy of the signal of interest component of the signal is determined. A cumulative distribution function for the received signal is calculated, and a cumulative distribution function of the signal of interest component of the received signal is then calculated based on the estimated variance in the sampled noise component, the determined energy of the signal of interest component of the signal, and the calculated cumulative distribution function for the received signal. |
FILED | Monday, June 21, 2021 |
APPL NO | 17/353766 |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 29/26 (20130101) Transmission H04B 15/00 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220014347 | TIAN et al. |
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FUNDED BY |
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APPLICANT(S) | INTELLIGENT FUSION TECHNOLOGY, INC. (Germantown, Maryland) |
ASSIGNEE(S) | |
INVENTOR(S) | Xin TIAN (Germantown, Maryland); Genshe CHEN (Germantown, Maryland); Khanh PHAM (Kirtland AFB, New Mexico); Erik BLASCH (Arlington, Virginia) |
ABSTRACT | A method for emulating a communication system with fast changing link condition, applied to a testbed system including an interference emulator, a transmitter, and a receiver, includes: by the transmitter, generating code-word symbols, in an initial symbol sequence, according to information bits; evaluating an interference condition and a time duration for each code-word symbol; reordering the code-word symbols to a reordered symbol sequence based on interference conditions; evaluating a total time duration of code-word symbols under each interference condition; and transmitting the code-word symbols in the reordered symbol sequence. The method also includes: by the interference emulator, obtaining the total time duration of code-word symbols under each interference condition from the transmitter; and providing an emulated interference environment by ordering the time durations of different interference conditions. The start time for transmitting code-word symbols with an interference condition is synchronized with the start time for emulating the interference condition. |
FILED | Thursday, July 09, 2020 |
APPL NO | 16/924853 |
CURRENT CPC | Transmission H04B 17/373 (20150115) H04B 17/3913 (20150115) Transmission of Digital Information, e.g Telegraphic Communication H04L 5/1453 (20130101) Original (OR) Class H04L 25/0204 (20130101) H04L 25/03343 (20130101) H04L 2025/03401 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 20220007677 | Gibbons et al. |
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FUNDED BY |
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APPLICANT(S) | PRAIRIE AQUATECH LLC (Brookings, South Dakota) |
ASSIGNEE(S) | PRAIRIE AQUATECH LLC (Brookings, South Dakota) |
INVENTOR(S) | William Gibbons (Brookings, South Dakota); Michael L. Brown (Volga, South Dakota) |
ABSTRACT | The present invention describes a bio-based process to produce high quality protein concentrate (HQPC) by converting plant derived celluloses into bioavailable protein via aerobic incubation, including the use of such HQPC so produced as a nutrient, including use as a fish meal replacement in aquaculture diets. |
FILED | Friday, September 17, 2021 |
APPL NO | 17/477676 |
CURRENT CPC | Protein Compositions for Foodstuffs; Working-up Proteins for Foodstuffs; Phosphatide Compositions for Foodstuffs A23J 1/14 (20130101) A23J 1/125 (20130101) Original (OR) Class A23J 1/148 (20130101) Fodder A23K 10/14 (20160501) A23K 10/38 (20160501) A23K 20/147 (20160501) A23K 40/20 (20160501) A23K 40/25 (20160501) A23K 50/80 (20160501) Technologies for Adaptation to Climate Change Y02A 40/818 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220007958 | Grayson et al. |
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FUNDED BY |
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APPLICANT(S) | Northwestern University (Evanston, Illinois) |
ASSIGNEE(S) | |
INVENTOR(S) | Matthew Allen Grayson (Evanston, Illinois); Chulin Wang (Evanston, Illinois); Claire Cecelia Onsager (Stoughton, Wisconsin); Can Cenap Aygen (Chicago, Illinois); Charles M. Costakis (Evanston, Illinois); Lauren E. Lang (Boulder, Colorado); Andreas Tzavelis (Demarest, New Jersey); John Ashley Rogers (Wilmette, Illinois) |
ABSTRACT | The disclosed 2-D and 3-D tomographic resistance imaging method improves tomographic resistance image resolution by adopting an orthogonal basis with the maximum number of elements N to describe the maximum resolution resistivity map ρ(r), where this number of elements N is set according to the number of electrodes Q; by defining the orthogonal basis according to any known constraints in the problem, thereby enhancing the resolution where it is needed; by positioning electrodes to be sensitive to these basis functions; and by choosing current I and voltage V contact electrode pairs that maximize signal-to-noise ratio. |
FILED | Friday, November 29, 2019 |
APPL NO | 17/295318 |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0536 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008346 | Wilson et al. |
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FUNDED BY |
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APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
ASSIGNEE(S) | |
INVENTOR(S) | John T. Wilson (Nashville, Tennessee); Daniel Shae (Nashville, Tennessee); Dinh Chuong Nguyen (Phu Nhuan District, Ho Chi Minh, Viet Nam) |
ABSTRACT | A graft copolymer and a method of delivering an active agent to a subject are provided. The graft copolymer includes a polymer backbone, a hydrophilic segment grafted to the polymer backbone, a pH-responsive segment grafted to the polymer backbone, and an endosomal disruption segment grafted to the polymer backbone. The method of delivering an active agent to a subject includes encapsulating the active agent with the graft copolymer and administering the encapsulated active agent to the subject. |
FILED | Wednesday, October 30, 2019 |
APPL NO | 17/290618 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5026 (20130101) Original (OR) Class Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 290/062 (20130101) C08F 2438/03 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008347 | Baxter et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Ryan Baxter (Merced, California); Sayantani Ghosh (Merced, California) |
ABSTRACT | Self-assembled organic ligand functionalized microcapsules encapsulating one or more substrates, which release the substrates upon activation with a power source, are provided. Compositions that include these microcapsules, as well as methods of making the microcapsules and releasing the encapsulated substrates are also provided. The structures, compositions and methods find use in a variety of applications, such as drug and cell encapsulation technologies, for direct delivery, control, and activation of medicines and therapies to specific tissues in a living host. |
FILED | Wednesday, November 20, 2019 |
APPL NO | 17/296187 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0009 (20130101) A61K 9/143 (20130101) A61K 9/5015 (20130101) A61K 9/5089 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008736 | Babakhani et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California); Texas Heart Institute (Houston, Texas) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Texas Heart Institute (Houston, Texas) |
INVENTOR(S) | Aydin Babakhani (Los Angeles, California); Hongming Lyu (Los Angeles, California); Razavi Mehdi (Houston, Texas); Mathews M. John (Houston, Texas); Allison Post (Houston, Texas) |
ABSTRACT | Systems and methods for heart stimulation in accordance with embodiments of the invention are illustrated. One embodiment includes a heart stimulation system, including a first wirelessly powered, leadless pacemaker, including a wireless power receiver tuned to a first frequency, an energy harvesting circuitry, a stimulation circuitry, and a stimulation electrode, a controller, including a wireless power signal generator, a wireless power transmitter tuned to the frequency, a processor, and a memory containing a stimulation control application, where the stimulation control application directs the processor to generate a power transfer signal using the first wireless power signal generator, and transmit the power transfer signal using the wireless power transmitter, wherein the wirelessly powered, leadless pacemaker receives the power transfer signal using the first wireless power receiver, and when receiving the power transfer signal, the energy harvesting circuitry stores power received via the wireless power receiver in at least one capacitor. |
FILED | Wednesday, November 20, 2019 |
APPL NO | 17/295005 |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/3684 (20130101) A61N 1/3756 (20130101) Original (OR) Class A61N 1/3787 (20130101) A61N 1/37288 (20130101) A61N 1/37512 (20170801) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008970 | Quigley et al. |
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FUNDED BY |
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APPLICANT(S) | Loci Controls, Inc. (Fall River, Massachusetts) |
ASSIGNEE(S) | |
INVENTOR(S) | Peter Quigley (Duxbury, Massachusetts); Ian Martin (Sharon, Massachusetts); Jack Rowbottom (Swansea, Massachusetts); Nicole Neff (Colorado Springs, Colorado) |
ABSTRACT | Systems and methods for controlling extraction of landfill gas from a landfill via a gas extraction system are provided herein. According to some aspects of the technology, there is provided site-level control methods for globally controlling one or more wells based on one or more characteristics of aggregate landfill gas collected from a plurality of wells at a gas output. According to some aspects of the technology, there is provided well-level control methods for locally controlling a first well based on or more characteristics of landfill gas collected from the first well. According to further aspects of the technology, there is provided hybrid control methods for making adjustments to a respective well based on both site-level and well-level control methods. |
FILED | Monday, July 13, 2020 |
APPL NO | 16/927471 |
CURRENT CPC | Disposal of Solid Waste B09B 1/006 (20130101) B09B 3/0016 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/123 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008971 | Quigley et al. |
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FUNDED BY |
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APPLICANT(S) | Loci Controls, Inc. (Fall River, Massachusetts) |
ASSIGNEE(S) | |
INVENTOR(S) | Peter Quigley (Duxbury, Massachusetts); Ian Martin (Sharon, Massachusetts); Jack Rowbottom (Swansea, Massachusetts); Nicole Neff (Colorado Springs, Colorado) |
ABSTRACT | Systems and methods for controlling extraction of landfill gas from a landfill via a gas extraction system are provided herein. According to some aspects of the technology, there is provided site-level control methods for globally controlling one or more wells based on one or more characteristics of aggregate landfill gas collected from a plurality of wells at a gas output. According to some aspects of the technology, there is provided well-level control methods for locally controlling a first well based on or more characteristics of landfill gas collected from the first well. According to further aspects of the technology, there is provided hybrid control methods for making adjustments to a respective well based on both site-level and well-level control methods. |
FILED | Monday, July 13, 2020 |
APPL NO | 16/927479 |
CURRENT CPC | Reclamation of Contaminated Soil B09C 1/005 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 34/00 (20130101) E21B 47/06 (20130101) E21B 49/0875 (20200501) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 11/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/004 (20130101) G01N 33/0044 (20130101) G01N 33/0047 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008972 | Quigley et al. |
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FUNDED BY |
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APPLICANT(S) | Loci Controls, Inc. (Fall River, Massachusetts) |
ASSIGNEE(S) | |
INVENTOR(S) | Peter Quigley (Duxbury, Massachusetts); Ian Martin (Sharon, Massachusetts); Jack Rowbottom (Swansea, Massachusetts); Nicole Neff (Colorado Springs, Colorado) |
ABSTRACT | Systems and methods for controlling extraction of landfill gas from a landfill via a gas extraction system are provided herein. According to some aspects of the technology, there is provided site-level control methods for globally controlling one or more wells based on one or more characteristics of aggregate landfill gas collected from a plurality of wells at a gas output. According to some aspects of the technology, there is provided well-level control methods for locally controlling a first well based on or more characteristics of landfill gas collected from the first well. According to further aspects of the technology, there is provided hybrid control methods for making adjustments to a respective well based on both site-level and well-level control methods. |
FILED | Monday, July 13, 2020 |
APPL NO | 16/927482 |
CURRENT CPC | Reclamation of Contaminated Soil B09C 1/005 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 34/00 (20130101) E21B 47/06 (20130101) E21B 49/0875 (20200501) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/004 (20130101) G01N 33/0044 (20130101) G01N 33/0047 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008973 | Quigley et al. |
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FUNDED BY |
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APPLICANT(S) | Loci Controls, Inc. (Fall River, Massachusetts) |
ASSIGNEE(S) | |
INVENTOR(S) | Peter Quigley (Duxbury, Massachusetts); Ian Martin (Sharon, Massachusetts); Jack Rowbottom (Swansea, Massachusetts); Nicole Neff (Colorado Springs, Colorado) |
ABSTRACT | Systems and methods for controlling extraction of landfill gas from a landfill via a gas extraction system are provided herein. According to some aspects of the technology, there is provided site-level control methods for globally controlling one or more wells based on one or more characteristics of aggregate landfill gas collected from a plurality of wells at a gas output. According to some aspects of the technology, there is provided well-level control methods for locally controlling a first well based on or more characteristics of landfill gas collected from the first well. According to further aspects of the technology, there is provided hybrid control methods for making adjustments to a respective well based on both site-level and well-level control methods. |
FILED | Monday, July 13, 2020 |
APPL NO | 16/927488 |
CURRENT CPC | Reclamation of Contaminated Soil B09C 1/005 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 34/00 (20130101) E21B 47/06 (20130101) E21B 49/0875 (20200501) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/004 (20130101) G01N 33/0044 (20130101) G01N 33/0047 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220009940 | Guo |
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FUNDED BY |
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APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
ASSIGNEE(S) | |
INVENTOR(S) | Maolin Guo (Dartmouth, Massachusetts) |
ABSTRACT | The present disclosure relates to compounds of Formula I, II, or III and compositions of the same, which are reversible off-on or ratiometric fluorescent iron sensors and are useful in live-cell imaging of labile iron ions and their quantification in subcellular compartments, as well as treatment of diseases associated with iron dyshomoestasis. |
FILED | Thursday, February 01, 2018 |
APPL NO | 16/485469 |
CURRENT CPC | Heterocyclic Compounds C07D 491/22 (20130101) C07D 491/107 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/643 (20130101) G01N 33/52 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220009944 | Beaudry et al. |
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FUNDED BY |
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APPLICANT(S) | Oregon State University (Corvallis, Oregon) |
ASSIGNEE(S) | Oregon State University (Corvallis, Oregon) |
INVENTOR(S) | Christopher M. Beaudry (Corvallis, Oregon); Xuan Ju (Danbury, Connecticut) |
ABSTRACT | Disclosed herein are embodiments of a compound having a Formula I or a salt, solvate, N-oxide, prodrug, diastereomer or enantiomer thereof. Also disclosed are derivative compounds made from the compound of Formula I. Certain derivative compounds have a Formula V-2, or a salt, solvate, N-oxide, prodrug, diastereomer or enantiomer thereof. Also disclosed are method for making and using the disclosed compounds. Certain disclosed embodiments are useful for treating and/or preventing certain diseases and/or disorders, including proliferation diseases, such as leukemia. |
FILED | Thursday, September 09, 2021 |
APPL NO | 17/470608 |
CURRENT CPC | Heterocyclic Compounds C07D 491/153 (20130101) C07D 498/06 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010055 | Nuckolls et al. |
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FUNDED BY |
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APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
INVENTOR(S) | Colin Nuckolls (New York, New York); Xavier Roy (New York, New York); Jake Carter Russell (New York, New York); Samuel R. Peurifoy (New York, New York) |
ABSTRACT | The present disclosure provides organic compounds having pseudocapacitive performance and methods of preparing said compounds. The organic compounds can include perylene diamine (PDI) subunits and hexaazatrinaphthylene (HATN) subunits. |
FILED | Friday, February 19, 2021 |
APPL NO | 17/180046 |
CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/122 (20130101) Original (OR) Class C08G 2261/12 (20130101) C08G 2261/228 (20130101) C08G 2261/411 (20130101) C08G 2261/3241 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/48 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010160 | Zhong et al. |
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FUNDED BY |
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APPLICANT(S) | The Research Foundation for The State University of new York (Binghamton, New York) |
ASSIGNEE(S) | |
INVENTOR(S) | Chuan-Jian Zhong (Endwell, New York); Shan Yan (Medford, New York); Shiyao Shan (Vestal, New York); Ning He (Xiamen, China PRC); Ning Kang (Irvine, California); Jin Luo (Vestal, New York) |
ABSTRACT | A low temperature sinterable copper nanoparticle or nanowire, comprising gold, zinc, nickel, tin, or aluminum as an alloying metal, and a capping agent. The nanoparticles or nanowires may be deposited on porous or fibrous substrates, the capping agent desorbed, and sintered at low temperature to form conductive traces or sensing elements. The nanoparticles or nanowires may be deposited by aerosol jet, inkjet or dispenser printers, for example. |
FILED | Friday, July 09, 2021 |
APPL NO | 17/305583 |
CURRENT CPC | Printing, Duplicating, Marking, or Copying Processes; Colour Printing, B41M 5/0023 (20130101) B41M 7/009 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/033 (20130101) C09D 11/037 (20130101) C09D 11/52 (20130101) Original (OR) Class Alloys C22C 9/00 (20130101) Pulp Compositions; Preparation Thereof Not Covered by Subclasses D21C or D21D; Impregnating or Coating of Paper; Treatment of Finished Paper Not Covered by Class B31 or Subclass D21G; Paper Not Otherwise Provided for D21H 19/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010284 | Silpe et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
INVENTOR(S) | Justin E. Silpe (Lawrenceville, New Jersey); Bonnie L. Bassler (Princeton, New Jersey) |
ABSTRACT | Disclosed are recombinant phages that infect and kill bacterial hosts in response to user-defined inputs. The components that encode the user-defined inputs can be combined, such that multiple inputs are maintained on a single recombinant phage, enabling precise control over the targeting strategy. The phages can be engineered to kill a specific bacterial species or multiple species simultaneously. Recombinant phages can also be engineered to harbor fluorescent and bioluminescent reporter genes that enable them to be used for tracking, detection, and in biosensing applications. Recombinant phages can also be used to lyse bacterial cells that produce recombinant proteins, as a rapid method to enable extraction and high-level purification of potentially valuable and/or industrially important proteins. Also disclosed is a system that can also be used to control the activity of a protein of interest, by taking advantage of an interaction between Qtip and a phage repressor protein; a phage repressor protein can be fused to a protein-of-interest, and by controlling the expression of qtip, the phage repressor protein fused to a protein-of-interest will be inactivated when Qtip is expressed and interacts with the phage repressor protein. |
FILED | Thursday, October 31, 2019 |
APPL NO | 17/289336 |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 15/73 (20130101) C12N 15/74 (20130101) C12N 2795/10121 (20130101) C12N 2795/10122 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010307 | Mischel et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California); Ludwig Institute for Cancer Research Ltd (La Jolla, California); The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Paul Mischel (La Jolla, California); Bing Ren (La Jolla, California); Kristen Turner (La Jolla, California); Sihan Wu (La Jolla, California); Vineet Bafna (Oakland, California); Nam-phuong Nguyen (Oakland, California); Howard Chang (Stanford, California) |
ABSTRACT | Provided herein are, inter alia, methods and compositions to detect, monitor and treat cancer, wherein the cancer includes amplified extrachromosomal oncogenes. The methods are useful for personalized treatment and exploit differential expression and chromatin structure of extrachromosomal oncogenes in cancer cells. |
FILED | Tuesday, December 10, 2019 |
APPL NO | 17/311980 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) Original (OR) Class C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2310/20 (20170501) C12N 2320/31 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010317 | BORDENSTEIN et al. |
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FUNDED BY |
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APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee); lNSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNI (Paris, France); THE UNIVERSITY OF CHICAGO (Chicago, Israel) |
ASSIGNEE(S) | |
INVENTOR(S) | Sarah BORDENSTEIN (Nashville, Tennessee); Julie REVEILLAUD (Montpellier, France); A. Murat EREN (Chicago, Illinois); Seth BORDENSTEIN (Nashville, Tennessee) |
ABSTRACT | The present disclosure relates to plasmids, systems, and methods for the transformation of Wolbachia. Disclosed herein are plasmids and systems for use in methods of transforming Wolbachia. The inventors have identified extrachromosomal plasmids within Wolbachia. Disclosed herein is a non-naturally occurring plasmid comprising a nucleic acid encoding a transposase. Disclosed herein is a method for transforming a Wolbachia cell, comprising introducing a non-naturally occurring plasmid into the cell, wherein the plasmid comprises a nucleic acid sequence capable of transforming a Wolbachia cell. |
FILED | Friday, November 15, 2019 |
APPL NO | 17/293634 |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/74 (20130101) Original (OR) Class C12N 2800/101 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220011249 | Yao et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Norman Ying Yao (Berkeley, California); Raymond Jeanloz (Berkeley, California); Thomas Mittiga (Berkeley, California); Prabudhya Bhattacharyya (Berkeley, California); Thomas J. Smart (Berkeley, California); Francisco Machado (Berkeley, California); Bryce Kobrin (Berkeley, California); Soonwon Choi (Berkeley, California); Joel Moore (Berkeley, California); Satcher Hsieh (Berkeley, California); Chong Zu (Berkeley, California) |
ABSTRACT | A pressure chamber has a chamber wall. The chamber wall includes a sensor integrated within the chamber wall, wherein the sensor integrated in the chamber wall comprises defects. A method of determining an effect of pressure on a material is further described. The method includes applying pressure to a material within a pressure chamber and to a pressure chamber wall of the pressure chamber, where the pressure chamber wall has defects. A signal from the defects is sensed while the material and the pressure chamber wall are under pressure. A property of the material is determined based on the sensed signal. |
FILED | Thursday, December 19, 2019 |
APPL NO | 17/312893 |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/28 (20170801) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/12 (20130101) G01N 23/20041 (20130101) Original (OR) Class G01N 2203/0488 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/46 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220011270 | Arvanitis et al. |
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APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
ASSIGNEE(S) | |
INVENTOR(S) | Costas Arvanitis (Atlanta, Georgia); Arpit Patel (Atlanta, Georgia); Scott Joseph Schoen, Jr. (Atlanta, Georgia); Zhigen Zhao (Atlanta, Georgia) |
ABSTRACT | This disclosure describes systems and methods for ultrasound imaging and targeting. In one example, the systems and methods improve targeting and imaging through a heterogenous medium by using the angular spectrum approach (ASA) alone or in combination with passive acoustic mapping (PAM). In another example, the systems and methods improve the ultrasound imaging of vessels using microbubbles. The imaging of the vessels is also aided by the ASA and PAM. A closed loop controller is described that adjusts the ultrasound pressure provided to a region of interest to a desired pressure based at least in part on the harmonic, ultra-harmonic, sub-harmonic, or broadband frequency ranges for the microbubbles. |
FILED | Thursday, November 07, 2019 |
APPL NO | 17/291504 |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/221 (20130101) G01N 29/348 (20130101) G01N 29/0654 (20130101) Original (OR) Class G01N 2291/102 (20130101) G01N 2291/02475 (20130101) G01N 2291/02483 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220011302 | Johnson, JR. et al. |
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APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | |
INVENTOR(S) | Alan T. Johnson, JR. (Philadelphia, Pennsylvania); Ye Lu (Philadelphia, Pennsylvania); Joseph J. Mitala, JR. (Rockville, Maryland); Bohdana Discher (Philadelphia, Pennsylvania); Brett R. Goldsmith (Philadelphia, Pennsylvania) |
ABSTRACT | Provided are devices and methods featuring a nanoelectronic interface between graphene devices (for example, field effect transistors or FETs) and biomolecules such as proteins, which in turn provides a pathway for production of bioelectronic devices that combine functionalities of the biomolecular and inorganic components. In one exemplary application, one may functionalize graphene FETs with fluorescent proteins to yield hybrids that respond to light at wavelengths defined by the optical absorption spectrum of the protein. The devices may also include graphene in electronic communication with a bio-molecule that preferentially binds to a particular analyte. |
FILED | Monday, September 13, 2021 |
APPL NO | 17/473412 |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/54306 (20130101) Original (OR) Class G01N 33/54353 (20130101) G01N 33/54373 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220011512 | Ramachandran et al. |
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APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
ASSIGNEE(S) | |
INVENTOR(S) | Siddharth Ramachandran (Boston, Massachusetts); Zelin Ma (Boston, Massachusetts) |
ABSTRACT | An optical fiber system exploits a principle of topological confinement for guided higher-order modes, in contrast to more conventional total-internal-reflection (TIR) confinement. The optical fiber has a geometry and index profile defining a cutoff wavelength for a predetermined L-mode of optical signal propagation in the optical fiber, where L is azimuthal mode index. An optical source subsystem is coupled to the optical fiber to establish an optical signal propagating in the optical fiber, wherein the optical signal has the predetermined L-mode and a wavelength being either (1) at least 15% above the cutoff wavelength such that the optical beam propagates as a topologically confined mode, or (2) sufficiently above the cutoff wavelength that, based on the L-mode of the optical beam, the optical beam propagates as a topologically confined mode having propagation loss less than 3 dB/meter. |
FILED | Sunday, May 09, 2021 |
APPL NO | 17/315314 |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/14 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220011535 | Monroe et al. |
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FUNDED BY |
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APPLICANT(S) | James Alan Monroe (College Station, Texas); David Scott Content (Spring, Texas); Jeremy Sean McAllister (Bryan, Texas); Jay Russell Zgarba (Sugar Land, Texas) |
ASSIGNEE(S) | |
INVENTOR(S) | James Alan Monroe (College Station, Texas); David Scott Content (Spring, Texas); Jeremy Sean McAllister (Bryan, Texas); Jay Russell Zgarba (Sugar Land, Texas) |
ABSTRACT | A lens alignment system and method is disclosed. The disclosed system/method integrates one or more lens retaining members/tubes (LRM/LRT) and focal length spacers (FLS) each comprising a metallic material product (MMP) specifically manufactured to have a thermal expansion coefficient (TEC) in a predetermined range via selection of the individual MMP materials and an associated MMP manufacturing process providing for controlled TEC. This controlled LRM/LRT TEC enables a plurality of optical lenses (POL) fixed along a common optical axis (COA) by the LRM/LRT to maintain precise interspatial alignment characteristics that ensure consistent and/or controlled series focal length (SFL) within the POL to generate a thermally neutral optical system (TNOS). Integration of the POL using this LRM/LRT/FLS lens alignment system reduces the overall TNOS implementation cost, reduces the overall TNOS mass, reduces TNOS parts component count, and increases the reliability of the overall optical system. |
FILED | Tuesday, September 07, 2021 |
APPL NO | 17/467719 |
CURRENT CPC | Alloys C22C 14/00 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/183 (20130101) Optical Elements, Systems, or Apparatus G02B 7/003 (20130101) G02B 7/028 (20130101) Original (OR) Class G02B 23/2407 (20130101) G02B 27/0012 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220011646 | Semmlinger et al. |
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APPLICANT(S) | William Marsh Rice University (Houston, Texas); Academia Sinica (Taipei, Taiwan) |
ASSIGNEE(S) | William Marsh Rice University (Houston, Texas); Academia Sinica (Taipei, Taiwan) |
INVENTOR(S) | Michael Semmlinger (Houston, Texas); Ming Lun Tseng (Taipei, Taiwan); Jian Yang (Houston, Texas); Ming Zhang (Houston, Texas); Din Ping Tsai (Taipei, Taiwan); Liangliang Dong (Houston, Texas); Arash Ahmadivand (Houston, Texas); Peter Nordlander (Houston, Texas); Nancy Jean Halas (Houston, Texas) |
ABSTRACT | A harmonic light-generating metasurface includes a base substrate and a plurality of structures, that include nonlinear material, that are disposed in a pattern on a surface of the base substrate. Each structure of the plurality of structures individually supports a magnetic dipole mode. An electromagnetic field enhancement of the magnetic dipole mode induces generation of a harmonic signal by the plurality of structures. Alternatively, a harmonic light-generating metasurface, includes a base substrate, a supporting substrate that includes a nonlinear material, and a plurality of paired structures disposed in a pattern on a surface of the supporting substrate. Each paired structure, of the plurality of paired structures, collectively supports a toroidal dipole mode. An electromagnetic field enhancement of the toroidal dipole mode penetrates the supporting substrate to induce generation of a harmonic signal by the supporting substrate. |
FILED | Tuesday, October 01, 2019 |
APPL NO | 17/281814 |
CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/37 (20130101) Original (OR) Class G02F 1/354 (20210101) G02F 2202/30 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220011664 | Talapin et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
ASSIGNEE(S) | |
INVENTOR(S) | Dmitri V. Talapin (La Grange Park, Illinois); Yuanyuan Wang (Nanjing, China PRC); Jia-Ahn Pan (Chicago, Illinois); Haoqi Wu (Chicago, Illinois) |
ABSTRACT | Ligand-capped inorganic particles, dispersions of the ligand-capped inorganic particles, and films composed of the ligand-capped inorganic particles are provided. Also provided are methods of patterning the films and electronic, photonic, and optoelectronic devices that incorporate the films. The ligands include bifunctional ligands and two-component ligand systems that include a photosensitive group, cation, or molecule. |
FILED | Friday, October 11, 2019 |
APPL NO | 17/283457 |
CURRENT CPC | Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/008 (20130101) G03F 7/20 (20130101) G03F 7/32 (20130101) G03F 7/0045 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220012850 | Ozcan et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Aydogan Ozcan (Los Angeles, California); Yair Rivenson (Los Angeles, California); Yichen Wu (Los Angeles, California) |
ABSTRACT | A trained deep neural network transforms an image of a sample obtained with a holographic microscope to an image that substantially resembles a microscopy image obtained with a microscope having a different microscopy image modality. Examples of different imaging modalities include bright-field, fluorescence, and dark-field. For bright-field applications, deep learning brings bright-field microscopy contrast to holographic images of a sample, bridging the volumetric imaging capability of holography with the speckle-free and artifact-free image contrast of bright-field microscopy. Holographic microscopy images obtained with a holographic microscope are input into a trained deep neural network to perform cross-modality image transformation from a digitally back-propagated hologram corresponding to a particular depth within a sample volume into an image that substantially resembles a microscopy image of the sample obtained at the same particular depth with a microscope having the different microscopy image modality. |
FILED | Thursday, November 14, 2019 |
APPL NO | 17/294384 |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/0008 (20130101) G02B 21/365 (20130101) Holographic Processes or Apparatus G03H 1/0005 (20130101) G03H 1/268 (20130101) G03H 2001/005 (20130101) Image Data Processing or Generation, in General G06T 5/002 (20130101) Original (OR) Class G06T 7/50 (20170101) G06T 2207/10056 (20130101) G06T 2207/10064 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220012890 | Wu et al. |
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FUNDED BY |
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APPLICANT(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
INVENTOR(S) | Xiaodong Wu (Iowa City, Iowa); Leixin Zhou (Iowa City, Iowa); John M Buatti (Iowa City, Iowa); Hui Xie (North Liberty, Iowa) |
ABSTRACT | An automated method for segmentation includes steps of receiving at a computing device an input image representing at least one surface and performing by the computing device image segmentation on the input image based on a graph surface segmentation model with deep learning. The deep learning may be used to parameterize the graph surface segmentation model. |
FILED | Thursday, July 01, 2021 |
APPL NO | 17/365572 |
CURRENT CPC | Image Data Processing or Generation, in General G06T 7/11 (20170101) Original (OR) Class G06T 7/0012 (20130101) G06T 7/162 (20170101) G06T 2207/10072 (20130101) G06T 2207/10132 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220012901 | Sun et al. |
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FUNDED BY |
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APPLICANT(S) | University of South Florida (Tampa, Florida) |
ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
INVENTOR(S) | Yu Sun (Tampa, Florida); David Andres Paulius (Tampa, Florida); Maxat Alibayev (Tampa, Florida) |
ABSTRACT | A method for motion recognition and embedding is disclosed. The method may include receiving a plurality of frames of an input video for extracting a feature vector of a motion in the plurality of frames, generating a plurality of sets of one or more motion component bits based on the feature vector and a plurality of classifiers, the plurality of sets corresponding to the plurality of classifiers, each set of one or more motion component bits representing a physical or mechanical attribute of the motion; and generating a motion code for a machine to execute the motion by combining the plurality of sets of one or more motion component bits. Other aspects, embodiments, and features are also claimed and described. |
FILED | Monday, July 12, 2021 |
APPL NO | 17/373276 |
CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00718 (20130101) G06K 9/00744 (20130101) Image Data Processing or Generation, in General G06T 7/248 (20170101) Original (OR) Class G06T 2207/10016 (20130101) G06T 2207/30241 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220012923 | LEBECK et al. |
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FUNDED BY |
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APPLICANT(S) | University of Washington (Seattle, Washington) |
ASSIGNEE(S) | University of Washington (Seattle, Washington) |
INVENTOR(S) | Kiron LEBECK (Seattle, Washington); Tadayoshi KOHNO (Seattle, Washington); Franziska ROESNER (Seattle, Washington) |
ABSTRACT | In some embodiments, an augmented reality system is provided. The augmented reality system is configured to detect real-world objects, create software objects that represent the real-world objects, receive requests from applications to present virtual objects at locations associated with the real-world objects, and to present the virtual objects. In some embodiments, an operating system of the augmented reality system is configured to resolve conflicts between requests from multiple applications. In some embodiments, the operating system of the augmented reality system is configured to provide information to applications to allow the applications to avoid or resolve conflicts amongst themselves. |
FILED | Wednesday, December 11, 2019 |
APPL NO | 17/413516 |
CURRENT CPC | Image Data Processing or Generation, in General G06T 11/00 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220013247 | Watkins et al. |
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FUNDED BY |
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APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
INVENTOR(S) | James Watkins (South Hadley, Massachusetts); Michael R. Beaulieu (Chicopee, Massachusetts); Nicholas R. Hendricks (South Deerfield, Massachusetts) |
ABSTRACT | Aspects relate to patterned nanostructures having a feature size not including film thickness of below 5 microns. The patterned nanostructures are made up of nanoparticles having an average particle size of less than 100 nm. A nanoparticle composition, which, in some cases, includes a binder, is applied to a substrate. A patterned mold used in concert with electromagnetic radiation function to manipulate the nanoparticle composition in forming the patterned nanostructure. In some embodiments, the patterned mold nanoimprints a pattern onto the nanoparticle composition and the composition is cured through UV or thermal energy, Three-dimensional patterned nanostructures may be formed. A number of patterned nanostructure layers may be prepared and joined together. In some cases, a patterned nanostructure may be formed as a layer that is releasable from the substrate upon which it is initially formed. Such releasable layers may be arranged to form a three-dimensional patterned nanostructure for suitable applications. |
FILED | Friday, September 24, 2021 |
APPL NO | 17/485281 |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/08 (20130101) Original (OR) Class H01B 3/10 (20130101) H01B 13/003 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0015 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/04 (20130101) H01M 6/40 (20130101) H01M 8/124 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220013324 | FAN |
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FUNDED BY |
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APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
INVENTOR(S) | Qi Hua FAN (Okemos, Michigan) |
ABSTRACT | A single beam plasma or ion source apparatus, including multiple and different power sources, is provided. An aspect of the present apparatus and method employs simultaneous excitation of an ion source by DC and AC, or DC and RF power supplies. Another aspect employs an ion source including multiple magnets and magnetic shunts arranged in a generally E cross-sectional shape. |
FILED | Thursday, September 23, 2021 |
APPL NO | 17/482833 |
CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/35 (20130101) C23C 14/46 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/08 (20130101) Original (OR) Class H01J 2237/0815 (20130101) H01J 2237/3146 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220013349 | JARROLD et al. |
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FUNDED BY |
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APPLICANT(S) | THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana) |
ASSIGNEE(S) | |
INVENTOR(S) | Martin F. JARROLD (Bloomington, Indiana); Aaron R. TODD (Bloomington, Indiana) |
ABSTRACT | An orbitrap may include elongated inner and outer electrodes, wherein the inner and outer electrodes each define two axially spaced apart electrode halves with a central transverse plane extending through the electrodes also passing between both sets of electrode halves, a cavity defined radially about and axially along the inner electrode between the two inner electrode halves and the two outer electrode halves, means for establishing an electric field configured to trap an ion in the cavity and to cause the trapped ion to rotate about, and oscillate axially along, the inner electrode, wherein the rotating and oscillating ion induces charges on the inner and outer electrode halves, and charge detection circuitry configured to detect the charges induced on the inner and on outer electrode halves, and to combine the detected charges for each oscillation to produce a measured ion charge signal. |
FILED | Friday, January 11, 2019 |
APPL NO | 17/293850 |
CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/425 (20130101) Original (OR) Class H01J 49/4255 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220013350 | JARROLD et al. |
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FUNDED BY |
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APPLICANT(S) | THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana) |
ASSIGNEE(S) | |
INVENTOR(S) | Martin F. JARROLD (Bloomington, Indiana); Daniel BOTAMANENKO (Bloomington, Indiana) |
ABSTRACT | A charge detection mass spectrometer may include an ion source, an electrostatic linear ion trap (ELIT) including a charge detection cylinder disposed between a pair of coaxially aligned ion mirrors, means for selectively establishing electric fields within the ion mirrors configured to cause the trapped ions in the ELIT to oscillate back and forth between the ion mirrors each time passing through the charge detection cylinder, and means for controlling a trajectory of the beam of ions entering the ELIT to cause the subsequently trapped ions to oscillate with different planar ion oscillation trajectories angularly offset from one another about the longitudinal axis with each extending along and crossing the longitudinal axis in each of the ion mirrors or with different cylindrical ion oscillation trajectories radially offset from one another about the longitudinal axis to form nested cylindrical trajectories each extending along the longitudinal axis. |
FILED | Friday, January 11, 2019 |
APPL NO | 17/293852 |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/623 (20210101) Electric Discharge Tubes or Discharge Lamps H01J 49/022 (20130101) H01J 49/025 (20130101) H01J 49/426 (20130101) H01J 49/4245 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220013417 | Sreenivasan et al. |
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FUNDED BY |
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APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
ASSIGNEE(S) | |
INVENTOR(S) | Sidlgata V. Sreenivasan (Austin, Texas); Shrawan Singhal (Austin, Texas); Lawrence R. Dunn (Austin, Texas) |
ABSTRACT | Various embodiments of the present technology generally relate to substrate planarization. More specifically, some embodiments of the present technology relate a versatile systems and methods for precision surface topography optimization known as planarization on nominally planar substrates. In some embodiments, a method for planarization of a patterned substrate using inkjets can determine the global and nanoscale topography and pattern information of the patterned substrate. Based upon the global and nanoscale topography and pattern information, a drop pattern can be determined and then dispensed on the patterned substrate. A gap between the patterned substrate and a superstrate causing the dispensed drops can be closed to form a substantially contiguous film. The substantially contiguous film can be cured and the superstrate can be separated from the patterned substrate with substantially contiguous film on the patterned substrate. |
FILED | Friday, December 13, 2019 |
APPL NO | 17/413523 |
CURRENT CPC | Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) G03F 7/16 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/042 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/31051 (20130101) H01L 22/12 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220013765 | Weng et al. |
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FUNDED BY |
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APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York) |
ASSIGNEE(S) | |
INVENTOR(S) | Guoming Weng (Guangdong, China PRC); Hang Wang (Brooklyn, New York); André D. Taylor (Brooklyn, New York) |
ABSTRACT | A composition comprising a graphitic carbon nitride material and a conductive carbon material coating may be used in electrodes or in batteries such as sodium ion batteries. The composition may be prepared using a method comprising the steps of providing a nitrogenous compound; adding a carbonaceous material to the nitrogenous compound to form a slurry; drying the slurry to form a coated mixture; and carbonizing the coated mixture. |
FILED | Friday, July 09, 2021 |
APPL NO | 17/371613 |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 21/0605 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/133 (20130101) Original (OR) Class H01M 4/1393 (20130101) H01M 10/054 (20130101) H01M 2004/028 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220013807 | Li et al. |
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FUNDED BY |
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APPLICANT(S) | Xiaowei Li (Philadelphia, Pennsylvania); Yongwei Zheng (Philadelphia, Pennsylvania); Christopher Li (Bala Cynwyd, Pennsylvania) |
ASSIGNEE(S) | |
INVENTOR(S) | Xiaowei Li (Philadelphia, Pennsylvania); Yongwei Zheng (Philadelphia, Pennsylvania); Christopher Li (Bala Cynwyd, Pennsylvania) |
ABSTRACT | Ionic liquid N-methyl-N-propyl-pyrrolidinium bis(fluorosulfonyl)imide (Pyr13FSI) was introduced into a hybrid network to obtain a series of gel polymer electrolytes (GPEs). Mechanical and electrochemical properties of the GPEs were tuned through controlling the network structure and ionic liquid contents, and ionic conductivity higher than 1 mS cm−1 at room temperature was achieved. The newly developed GPEs are flame-retardant and show excellent thermal and electrochemical stability as well as ultra-stability with lithium metal anode. Symmetrical lithium cells with the GPEs exhibit a stable cycling over 6800 h at a current density of 0.1 mA cm−2 and stable lithium stripping-plating at 1 mA cm−2, the highest current density reported for ionic liquid-based GPEs. Moreover, Li/LiFePO4 batteries with the obtained GPEs exhibit desirable cycling stability and rate performance over a wide temperature range from 0° C. to 90° C. |
FILED | Sunday, May 02, 2021 |
APPL NO | 17/246681 |
CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/336 (20130101) C08G 2220/00 (20130101) C08G 2650/20 (20130101) C08G 2650/50 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0565 (20130101) Original (OR) Class H01M 10/0567 (20130101) H01M 10/4235 (20130101) H01M 2004/027 (20130101) H01M 2300/0085 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220014158 | Bameri et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Hadi Bameri (Davis, California); Omeed Momeni (Davis, California) |
ABSTRACT | A power amplifier (amp) is disclosed. This power amp can include a first transistor configured in the common source (CS) amplification mode, wherein the gate terminal of the first transistor is used as the input port of the power amp; and a second transistor configured in the common gate (CG) amplification mode, wherein the drain terminal of the second transistor is used as the output port of the power amp. The power amp also includes a first inductive component coupled between the drain terminal of the first transistor and the ground to increase the impedance between the drain terminal of the first transistor and the ground, thereby increasing an output power at the output port. The power amp additionally includes a second inductive component coupled between the drain terminal of the first transistor and the source terminal of the second transistor to increase the conductance in the output admittance at the output port, thereby further increasing the output power at the output port. |
FILED | Wednesday, July 07, 2021 |
APPL NO | 17/369879 |
CURRENT CPC | Amplifiers H03F 3/211 (20130101) Original (OR) Class H03F 2200/451 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220014764 | Mazumdar et al. |
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FUNDED BY |
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APPLICANT(S) | University of Washington (Seattle, Washington) |
ASSIGNEE(S) | University of Washington (Seattle, Washington) |
INVENTOR(S) | Amrita Mazumdar (Seattle, Washington); Luis Ceze (Seattle, Washington); Mark H. Oskin (Seattle, Washington) |
ABSTRACT | Examples of systems and methods described herein may provide saliency-based video compression. A saliency map associated with a video may be generated and/or provided. A tile configuration may be selected for the video and quality settings assigned to each tile in accordance with the saliency map. The video may then be compressed (e.g., encoded) in tiles in accordance with the quality settings. Compressed videos may be stored together with saliency metadata, facilitating storage management and/or re-compression. |
FILED | Tuesday, August 06, 2019 |
APPL NO | 17/281915 |
CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/036 (20130101) G06K 9/00765 (20130101) G06K 9/4671 (20130101) Pictorial Communication, e.g Television H04N 19/40 (20141101) H04N 19/115 (20141101) H04N 19/119 (20141101) H04N 19/176 (20141101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 20220008380 | Jacobson et al. |
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FUNDED BY |
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APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | |
INVENTOR(S) | Daniel A. Jacobson (Oak Ridge, Tennessee); Erica Teixeira Prates (Oak Ridge, Tennessee); John I. Miller (Oak Ridge, Tennessee); Michael R. Garvin (Oak Ridge, Tennessee) |
ABSTRACT | This disclosure provides methods for treating a SARS-CoV-2 infection in a subject comprising administering to the subject an effective amount of an inhibitor of COVID-induced RAS imbalance, that downregulates, for example, the Bradykinin system, the Renin-Angiotensin system, the hyaluronan synthesis pathway, or the fibrinogenesis pathway. |
FILED | Wednesday, July 07, 2021 |
APPL NO | 17/368911 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/58 (20130101) A61K 31/59 (20130101) A61K 31/352 (20130101) Original (OR) Class A61K 38/08 (20130101) A61K 38/2292 (20130101) A61K 45/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008898 | BECKHAM et al. |
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FUNDED BY |
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APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
ASSIGNEE(S) | |
INVENTOR(S) | Gregg Tyler BECKHAM (Golden, Colorado); Lucas Delano ELLIS (Boulder, Colorado) |
ABSTRACT | The present disclosure relates to a composition that includes a dehydrogenation (D) catalyst and a cross metathesis (CM) catalyst, where both catalysts are positioned on a support. |
FILED | Thursday, July 08, 2021 |
APPL NO | 17/370244 |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 6/001 (20130101) B01J 21/04 (20130101) B01J 23/42 (20130101) Original (OR) Class B01J 37/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220009124 | Xiao et al. |
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FUNDED BY |
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APPLICANT(S) | Clemson University Research Foundation (Clemson, South Carolina) |
ASSIGNEE(S) | |
INVENTOR(S) | Hai Xiao (Clemson, South Carolina); Jianhua Tong (Central, South Carolina); Fei Peng (Clemson, South Carolina); Kyle S. Brinkman (Clemson, South Carolina); Shenglong Mu (Clemson, South Carolina); Jincheng Lei (Clemson, South Carolina); Yuzhe Hong (Clemson, South Carolina); Hua Huang (Clemson, South Carolina); Rajendra Bordia (Seneca, South Carolina) |
ABSTRACT | A method for fabricating a protonic ceramic energy device includes: coating an electrolyte layer on an anode layer; and densifying the electrolyte layer by a rapid laser reactive sintering (RLRS) process on the electrolyte layer and/or the anode layer to form a half-cell comprising a dense electrolyte and a porous anode. |
FILED | Wednesday, December 30, 2020 |
APPL NO | 17/138173 |
CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/402 (20130101) B23K 2103/52 (20180801) Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 1/001 (20130101) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 40/20 (20200101) Manufacture, Shaping, or Supplementary Processes C03B 19/01 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220009813 | Kostecki et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Robert Kostecki (Lafayette, California); Ravi S. Prasher (Danville, California); Akanksha K. Menon (Berkeley, California); Andrew Z. Haddad (Berkeley, California); Jeffrey J. Urban (Emeryville, California) |
ABSTRACT | This disclosure provides systems, methods, and apparatus related to water desalination. In one aspect, a method includes generating a diluted draw solution using forward osmosis. Wastewater is on a first side of an osmotic membrane and a draw solution is on a second side of the osmotic membrane. The draw solution comprises a mixture of water and an ionic liquid. Water in the wastewater diffuses across the osmotic membrane to the draw solution to form the diluted draw solution. The diluted draw solution is heated using a photonic heater to a temperature above a lower critical solution temperature (LCST) of the ionic liquid to phase separate the diluted draw solution into the ionic liquid and treated water. |
FILED | Thursday, July 08, 2021 |
APPL NO | 17/370379 |
CURRENT CPC | Separation B01D 61/04 (20130101) B01D 61/005 (20130101) B01D 61/027 (20130101) B01D 61/58 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/445 (20130101) C02F 9/00 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010137 | Naskar et al. |
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FUNDED BY |
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APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Amit K. Naskar (Knoxville, Tennessee); Ngoc A. Nguyen (Oak Ridge, Tennessee) |
ABSTRACT | A solid polymer blend material comprising: (i) a lignin-acrylonitrile component containing a homogeneous blend of a lignin component and an acrylonitrile-containing rubber component; and (ii) a styrene-containing thermoplastic component that is non-elastomeric; wherein components (i) and (ii) are homogeneously dispersed in the polymer blend material. Methods for producing the blend material are also described. Methods for producing objects made of the blend material by melt extrusion are also described, comprising: (a) melt blending components (i) and (ii) to form a polymer blend in which components (i) and (ii) are homogeneously blended, wherein the polymer blend exhibits a melt viscosity of no more than 2000 Pa·s at a shear rate of 100-1000 s−1 and when heated to a temperature of no more than 240° C.; and (b) forming an object made of said polymer blend material. |
FILED | Tuesday, September 28, 2021 |
APPL NO | 17/487061 |
CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/106 (20170801) B29C 64/118 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 70/00 (20141201) Derivatives of Natural Macromolecular Compounds C08H 6/00 (20130101) Compositions of Macromolecular Compounds C08L 9/02 (20130101) C08L 25/06 (20130101) C08L 25/14 (20130101) C08L 55/02 (20130101) C08L 97/005 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010429 | Yacout et al. |
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FUNDED BY |
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APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
ASSIGNEE(S) | |
INVENTOR(S) | Abdellatif M. Yacout (Naperville, Illinois); Sumit Bhattacharya (Darien, Illinois); Yinbin Miao (Naperville, Illinois); Nicolas E. Stauff (Oak Park, Illinois) |
ABSTRACT | Provided herein is a hydrogen permeation barrier coating, a coated substrate, and methods of coating a substrate. |
FILED | Friday, July 10, 2020 |
APPL NO | 16/925782 |
CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/06 (20130101) C23C 16/403 (20130101) C23C 16/45529 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010437 | Kuhl et al. |
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FUNDED BY |
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APPLICANT(S) | Opus 12 Incorporated (Berkeley, California); The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Kendra P. Kuhl (Oakland, California); Etosha R. Cave (Berkeley, California); George Leonard (Oakland, California) |
ABSTRACT | A platform technology that uses a novel membrane electrode assembly including a cathode layer comprising a reduction catalyst and a first anion-and-cation-conducting polymer, an anode layer comprising an oxidation catalyst and a cation-conducting polymer, a membrane layer comprising a cation-conducting polymer, the membrane layer arranged between the cathode layer and the anode layer and conductively connecting the cathode layer and the anode layer, in a COx reduction reactor has been developed. The reactor can be used to synthesize a broad range of carbon-based compounds from carbon dioxide. |
FILED | Thursday, July 08, 2021 |
APPL NO | 17/369952 |
CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/25 (20210101) C25B 9/23 (20210101) Original (OR) Class C25B 11/051 (20210101) C25B 11/057 (20210101) C25B 13/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010623 | Su et al. |
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FUNDED BY |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | |
INVENTOR(S) | Jiann-Cherng Su (Albuquerque, New Mexico); Somuri V. Prasad (Albuquerque, New Mexico); Rand Garfield (Corrales, New Mexico) |
ABSTRACT | A coating architecture is disclosed that includes a substrate having a surface finish Ra of 0.3μ or finer, an intermediate layer overlying and in contact with the substrate; and a solid lubricant layer overlying and in contact with the intermediate layer. The test results of applying the coating architecture to a reciprocating hammer drill utilizing the coating is also disclosed. |
FILED | Monday, September 27, 2021 |
APPL NO | 17/485749 |
CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 9/007 (20130101) B32B 15/18 (20130101) B32B 2311/18 (20130101) B32B 2313/04 (20130101) B32B 2315/02 (20130101) Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 4/003 (20130101) Original (OR) Class E21B 4/14 (20130101) E21B 17/1007 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010662 | Guyer et al. |
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FUNDED BY |
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APPLICANT(S) | Chevron U.S.A. Inc. (San Ramon, California); Triad National Security, LLC (Los Alamos, New Mexico) |
ASSIGNEE(S) | |
INVENTOR(S) | Robert A. Guyer (Los Alamos, New Mexico); Timothy James Ulrich, II (Los Alamos, New Mexico); James A. Ten Cate (Los Alamos, New Mexico); Harvey Edwin Goodman (Houston, Texas) |
ABSTRACT | Strain information may define strain of a material to stress. The strain of the material may be decomposed into classical strain, hysteretic strain, and residual strain. The classical strain, the hysteretic strain, and the residual strain may be used to facilitate modeling of the material. For example, the classical strain, the hysteretic strain, and the residual strain of a rock may be used to facilitate modeling of a subsurface region that includes the rock such as a reservoir simulation to predict hydrocarbon recovery. |
FILED | Friday, July 09, 2021 |
APPL NO | 17/371566 |
CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/16 (20130101) Original (OR) Class Electric Digital Data Processing G06F 30/20 (20200101) G06F 2111/10 (20200101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010684 | BALDWIN et al. |
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FUNDED BY |
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APPLICANT(S) | General Electric Company (Schenectady, New York) |
ASSIGNEE(S) | |
INVENTOR(S) | Donald Joseph BALDWIN (Galway, New York); Joshua Lee MARGOLIES (Niskayuna, New York); Jacob John Kittleson (Greenville, South Carolina) |
ABSTRACT | A method of protecting a gas turbine component for operation in a high temperature environment that includes the gas turbine component including a substrate having a silicon-containing layer, wherein the gas turbine component has a curved surface; forming a flexible mask configured to cover the curved surface of the gas turbine component, the flexible mask including a plurality of slots disposed in a pattern; disposing the flexible mask in direct contact with the curved surface of the gas turbine component; applying a bondcoat onto the flexible mask and the gas turbine component, such that bondcoat fills the plurality of slots and contacts the curved surface; and removing the flexible mask by heat or chemical reaction, such that, after removing the flexible mask, the curved surface of the gas turbine component comprises a patterned bondcoat layer in the pattern defined by the flexible mask. |
FILED | Monday, September 27, 2021 |
APPL NO | 17/485732 |
CURRENT CPC | Spraying Apparatus; Atomising Apparatus; Nozzles B05B 12/20 (20180201) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/322 (20130101) B05D 3/12 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 41/009 (20130101) C04B 41/52 (20130101) C04B 41/89 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/288 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2300/611 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010833 | RIOT et al. |
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FUNDED BY |
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APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Vincent RIOT (Oakland, California); Darrell CARTER (Livermore, California); Todd Alan DECKER (Grants Pass, Oregon) |
ABSTRACT | The present disclosure relates to a reduced friction torsion component system that makes use of a first frame portion adapted to be coupled to, or integrally formed with, a first object, and forming a first bore, and a second frame portion adapted to be coupled to, or integrally formed with, a second object, and forming a second bore. The two bores are axially aligned and receive at least one elongated hinge component. The elongated hinge component operates to both couple the first and second frame portions together for pivoting movement relative to one another, and also provides a torsional biasing force to enable pivotal deployment from a first position to a second position of one of the first or second frame portions. |
FILED | Monday, July 13, 2020 |
APPL NO | 16/927235 |
CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/443 (20130101) Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 7/065 (20130101) Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 11/12 (20130101) Original (OR) Class F16C 2202/28 (20130101) F16C 2204/42 (20130101) F16C 2204/52 (20130101) F16C 2226/00 (20130101) F16C 2226/60 (20130101) F16C 2229/00 (20130101) F16C 2240/70 (20130101) F16C 2326/47 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010929 | Miao et al. |
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FUNDED BY |
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APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
ASSIGNEE(S) | |
INVENTOR(S) | Yinbin Miao (Naperville, Illinois); Nicolas E. Stauff (Oak Park, Illinois); Sumit Bhattacharya (Darien, Illinois); Abdellatif M. Yacout (Naperville, Illinois); Taek K. Kim (Naperville, Illinois) |
ABSTRACT | A gas enclosure of can include a refractory metal liner adapted to surround and enclose a gas to be contained; a ceramic matrix composite cladding; and a diffusion barrier layer disposed between the refractory metal liner and the ceramic matrix composite cladding. |
FILED | Friday, July 10, 2020 |
APPL NO | 16/925839 |
CURRENT CPC | Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 1/10 (20130101) Original (OR) Class F17C 1/14 (20130101) F17C 2203/0604 (20130101) F17C 2203/0607 (20130101) F17C 2203/0639 (20130101) F17C 2203/0646 (20130101) F17C 2203/0648 (20130101) F17C 2209/225 (20130101) F17C 2221/011 (20130101) F17C 2221/012 (20130101) F17C 2221/017 (20130101) F17C 2260/053 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220011188 | Kotovsky et al. |
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FUNDED BY |
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APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Jack Kotovsky (Alameda, California); Taylor Bevis (Bothell, Washington) |
ABSTRACT | Measurement of pressure of a fluid in a vessel using a cantilever spring in the vessel; a magnet connected to the cantilever spring in the vessel; an electromagnet outside of the vessel operatively connected to the magnet and the cantilever spring in the vessel, wherein the electromagnet induces movement of the magnet and the cantilever spring in the vessel, and wherein the movement is related to the pressure of the fluid in the vessel; a receiving coil operatively positioned relative to the magnet, wherein movement of the cantilever spring and the magnet in the vessel creates an electromotive response in the coil; and a controller analyzer connected to the receiving coil, wherein the controller analyzer uses the electromotive response in the coil for measuring the pressure of the fluid in the vessel. |
FILED | Tuesday, September 28, 2021 |
APPL NO | 17/449168 |
CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 9/02 (20130101) G01L 9/007 (20130101) G01L 9/10 (20130101) G01L 9/12 (20130101) G01L 9/14 (20130101) Original (OR) Class G01L 9/0051 (20130101) G01L 9/0072 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220011249 | Yao et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Norman Ying Yao (Berkeley, California); Raymond Jeanloz (Berkeley, California); Thomas Mittiga (Berkeley, California); Prabudhya Bhattacharyya (Berkeley, California); Thomas J. Smart (Berkeley, California); Francisco Machado (Berkeley, California); Bryce Kobrin (Berkeley, California); Soonwon Choi (Berkeley, California); Joel Moore (Berkeley, California); Satcher Hsieh (Berkeley, California); Chong Zu (Berkeley, California) |
ABSTRACT | A pressure chamber has a chamber wall. The chamber wall includes a sensor integrated within the chamber wall, wherein the sensor integrated in the chamber wall comprises defects. A method of determining an effect of pressure on a material is further described. The method includes applying pressure to a material within a pressure chamber and to a pressure chamber wall of the pressure chamber, where the pressure chamber wall has defects. A signal from the defects is sensed while the material and the pressure chamber wall are under pressure. A property of the material is determined based on the sensed signal. |
FILED | Thursday, December 19, 2019 |
APPL NO | 17/312893 |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/28 (20170801) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/12 (20130101) G01N 23/20041 (20130101) Original (OR) Class G01N 2203/0488 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/46 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220011512 | Ramachandran et al. |
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FUNDED BY |
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APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
ASSIGNEE(S) | |
INVENTOR(S) | Siddharth Ramachandran (Boston, Massachusetts); Zelin Ma (Boston, Massachusetts) |
ABSTRACT | An optical fiber system exploits a principle of topological confinement for guided higher-order modes, in contrast to more conventional total-internal-reflection (TIR) confinement. The optical fiber has a geometry and index profile defining a cutoff wavelength for a predetermined L-mode of optical signal propagation in the optical fiber, where L is azimuthal mode index. An optical source subsystem is coupled to the optical fiber to establish an optical signal propagating in the optical fiber, wherein the optical signal has the predetermined L-mode and a wavelength being either (1) at least 15% above the cutoff wavelength such that the optical beam propagates as a topologically confined mode, or (2) sufficiently above the cutoff wavelength that, based on the L-mode of the optical beam, the optical beam propagates as a topologically confined mode having propagation loss less than 3 dB/meter. |
FILED | Sunday, May 09, 2021 |
APPL NO | 17/315314 |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/14 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220011535 | Monroe et al. |
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FUNDED BY |
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APPLICANT(S) | James Alan Monroe (College Station, Texas); David Scott Content (Spring, Texas); Jeremy Sean McAllister (Bryan, Texas); Jay Russell Zgarba (Sugar Land, Texas) |
ASSIGNEE(S) | |
INVENTOR(S) | James Alan Monroe (College Station, Texas); David Scott Content (Spring, Texas); Jeremy Sean McAllister (Bryan, Texas); Jay Russell Zgarba (Sugar Land, Texas) |
ABSTRACT | A lens alignment system and method is disclosed. The disclosed system/method integrates one or more lens retaining members/tubes (LRM/LRT) and focal length spacers (FLS) each comprising a metallic material product (MMP) specifically manufactured to have a thermal expansion coefficient (TEC) in a predetermined range via selection of the individual MMP materials and an associated MMP manufacturing process providing for controlled TEC. This controlled LRM/LRT TEC enables a plurality of optical lenses (POL) fixed along a common optical axis (COA) by the LRM/LRT to maintain precise interspatial alignment characteristics that ensure consistent and/or controlled series focal length (SFL) within the POL to generate a thermally neutral optical system (TNOS). Integration of the POL using this LRM/LRT/FLS lens alignment system reduces the overall TNOS implementation cost, reduces the overall TNOS mass, reduces TNOS parts component count, and increases the reliability of the overall optical system. |
FILED | Tuesday, September 07, 2021 |
APPL NO | 17/467719 |
CURRENT CPC | Alloys C22C 14/00 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/183 (20130101) Optical Elements, Systems, or Apparatus G02B 7/003 (20130101) G02B 7/028 (20130101) Original (OR) Class G02B 23/2407 (20130101) G02B 27/0012 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220011742 | Shusteff et al. |
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FUNDED BY |
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APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Maxim Shusteff (Piedmont, California); Kyle Champley (Pleasanton, California); Erika Jo Fong (San Ramon, California); Hayden Taylor (Berkeley, California); Chi Chung Li (Berkeley, California); Trevor Rongey, JR. (Livermore, California); Sui Man Luk (Berkeley, California); Heting Fu (Berkeley, California); Samira Feili (Berkeley, California); Joseph Toombs (Berkeley, California); Hossein Heidari (Berkeley, California) |
ABSTRACT | A system for determining a light intensity field for use in manufacturing a 3D object from a volume of material. The system receives a 3D specification of a 3D geometry for the 3D object that specifies voxels within the volume that contain material that is to be part of the 3D object. The system employs a cost function for effectiveness of a light intensity field in manufacturing the 3D object. The cost function may be an adjoint of an Attenuated Radon Transform that models an energy dose that each voxel would receive during manufacture of the 3D object using the light intensity field. The system applies an optimization technique that employs the cost function to generate a measure of the effectiveness of possible light intensity fields and outputs an indication of a light intensity field that will be effective in manufacturing the 3D object. |
FILED | Monday, July 13, 2020 |
APPL NO | 16/927469 |
CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/4099 (20130101) Original (OR) Class G05B 2219/49023 (20130101) Image Data Processing or Generation, in General G06T 7/0004 (20130101) G06T 2207/30108 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220012178 | Michelogiannakis et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Georgios Michelogiannakis (Berkeley, California); John Shalf (Oakland, California) |
ABSTRACT | A last-level collective hardware prefetcher (LLCHP) is described. The LLCHP is to detect a first off-chip memory access request by a first processor core of a plurality of processor cores. The LLCHP is further to determine, based on the first off-chip memory access request, that first data associated with the first off-chip memory access request is associated with second data of a second processor core of the plurality of processor cores. The LLCHP is further to prefetch the first data and the second data based on the determination. |
FILED | Wednesday, November 06, 2019 |
APPL NO | 17/295797 |
CURRENT CPC | Electric Digital Data Processing G06F 12/0811 (20130101) G06F 12/0835 (20130101) G06F 12/0862 (20130101) Original (OR) Class G06F 15/7825 (20130101) G06F 2212/6026 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220012367 | Ramanan et al. |
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FUNDED BY |
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APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
ASSIGNEE(S) | |
INVENTOR(S) | Paritosh P. Ramanan (Atlanta, Georgia); Nagi Z. Gebraeel (Marietta, Georgia) |
ABSTRACT | An exemplary blockchain-based decentralized computing system and method are disclosed for industrial analytics applications. The exemplary system and method leverage blockchain technology to deliver and execute privacy-preserving decentralized predictive analytics, machine learning, and optimization operations for various industrial applications using a set of self-contained analytics block smart contracts that can be readily utilized and in analytics applications to deploy across multiple sites. |
FILED | Friday, July 09, 2021 |
APPL NO | 17/372064 |
CURRENT CPC | Electric Digital Data Processing G06F 8/41 (20130101) G06F 11/3688 (20130101) G06F 16/27 (20190101) G06F 16/2379 (20190101) G06F 21/64 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220013243 | Miao et al. |
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FUNDED BY |
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APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
ASSIGNEE(S) | |
INVENTOR(S) | Yinbin Miao (Naperville, Illinois); Nicolas E. Stauff (Oak Park, Illinois); Sumit Bhattacharya (Darien, Illinois); Abdellatif M. Yacout (Naperville, Illinois); Taek K. Kim (Naperville, Illinois) |
ABSTRACT | Provided herein is a moderation module and a thermal neutron micro-reactor. |
FILED | Friday, July 10, 2020 |
APPL NO | 16/926132 |
CURRENT CPC | Nuclear Reactors G21C 5/12 (20130101) Original (OR) Class G21C 15/08 (20130101) Nuclear Power Plant G21D 5/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220013268 | GE et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | |
INVENTOR(S) | Shencheng GE (Boston, Massachusetts); George M. WHITESIDES (Newton, Massachusetts) |
ABSTRACT | A magnetic levitation system is described, including a first cylinder-shaped magnet; a second cylinder-shaped magnet coaxially aligned with the first cylinder-shaped magnet; and a first cavity coaxially aligned with the first cylinder-shaped magnet; wherein the surfaces of the like-poles of the first and second cylinder-shaped magnets are parallel to each other and face each other to result in a linear magnetic field between the first and the second magnets. Methods of using a magnetic levitation system for analyzing a diamagnetic or paramagnetic sample are also described. |
FILED | Thursday, September 26, 2019 |
APPL NO | 17/279419 |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 9/00 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 7/0236 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220013671 | Zhao et al. |
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FUNDED BY |
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APPLICANT(S) | Yuji Zhao (Chandler, Arizona); Chen Yang (Tempe, Arizona); Houqiang Fu (Tempe, Arizona); Xuanqi Huang (Tempe, Arizona); Kai Fu (Tempe, Arizona) |
ASSIGNEE(S) | |
INVENTOR(S) | Yuji Zhao (Chandler, Arizona); Chen Yang (Tempe, Arizona); Houqiang Fu (Tempe, Arizona); Xuanqi Huang (Tempe, Arizona); Kai Fu (Tempe, Arizona) |
ABSTRACT | Fabricating a vertical-channel junction field-effect transistor includes forming an unintentionally doped GaN layer on a bulk GaN layer by metalorganic chemical vapor deposition, forming a Cr/SiO2 hard mask on the unintentionally doped GaN layer, patterning a fin by electron beam lithography, defining the Cr and SiO2 hard masks by reactive ion etching, improving a regrowth surface with inductively coupled plasma etching, removing hard mask residuals, regrowing a p-GaN layer, selectively etching the p-GaN layer, forming gate electrodes by electron beam evaporation, and forming source and drain electrodes by electron beam evaporation. The resulting vertical-channel junction field-effect transistor includes a doped GaN layer, an unintentionally doped GaN layer on the doped GaN layer, and a p-GaN regrowth layer on the unintentionally doped GaN layer. Portions of the p-GaN regrowth layer are separated by a vertical channel of the unintentionally doped GaN layer. |
FILED | Monday, July 12, 2021 |
APPL NO | 17/372810 |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/3065 (20130101) H01L 21/3081 (20130101) H01L 29/1058 (20130101) H01L 29/2003 (20130101) H01L 29/8083 (20130101) Original (OR) Class H01L 29/66446 (20130101) H01L 29/66909 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220013704 | Chen et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Renkun Chen (San Diego, California); Sahngki Hong (La Jolla, California) |
ABSTRACT | Thermoelectric devices (TE) devices may be used to power wearable electronics, such as watches and sensors by harvesting heat from the body. These TE devices may fully power or partially power the wearable devices to extend a usage time, or to recharge a battery. In other example embodiments, TE devices can be used to provide heating and/or cooling. The TE devices can be integrated into garments such as clothes, vests, and armbands for outdoor and indoor environments. For outdoor environments, applications include, but are not limited to, sports such as golfing, bicycling, running, walking, training, soccer, hiking, and other outdoor activities related to occupations, such as construction, fire-fighting, military operations, law enforcement, farming, underground mining, and so on. In other example embodiments, TE devices can be used to provide thermal camouflaging for people and objects so as to not be seen by thermal imaging devices. |
FILED | Wednesday, November 20, 2019 |
APPL NO | 17/295851 |
CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 31/04 (20190201) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/30 (20130101) H01L 35/32 (20130101) Original (OR) Class H01L 35/34 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220013733 | Li |
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FUNDED BY |
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APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
ASSIGNEE(S) | |
INVENTOR(S) | Jian Li (Tempe, Arizona) |
ABSTRACT | A white organic light emitting device comprises a first electrode; a hole transporting layer in contact with the first electrode; a second electrode; an electron transporting layer in contact with the second electrode; and an emissive layer between the hole transporting layer and the electron transporting layer. The emissive layer comprises a host, a fluorescent emitter, and a phosphorescent emitter. The fluorescent emitter harvests singlet excitons and emits blue light, and the phosphorescent emitter harvests triplet excitons and emits yellow-amber light. |
FILED | Tuesday, June 15, 2021 |
APPL NO | 17/347716 |
CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/008 (20130101) H01L 51/0084 (20130101) Original (OR) Class H01L 51/5056 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220013787 | Gleason et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | |
INVENTOR(S) | Karen K. Gleason (Cambridge, Massachusetts); Fikile Brushett (Cambridge, Massachusetts); Charles Wan (Cambridge, Massachusetts); Antoni Forner-Cuenca (Eindhoven, Netherlands); Meysam Heydari Gharahcheshmeh (Somerville, Massachusetts); Yasser Ashraf Gandomi (Somerville, Massachusetts) |
ABSTRACT | The present disclosure relates to electrodes comprising a polymer film and a substrate, wherein the polymer film has a thickness of about 5 nm to about 600 nm. The present disclosure also relates to electrochemical cells and batteries comprising the electrodes disclosed herein. The present disclosure also relates to methods of making the electrodes disclosed herein. |
FILED | Thursday, July 08, 2021 |
APPL NO | 17/370611 |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/366 (20130101) H01M 4/368 (20130101) H01M 4/0404 (20130101) H01M 4/624 (20130101) Original (OR) Class H01M 4/663 (20130101) H01M 8/188 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220013800 | Sankarasubramanian et al. |
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FUNDED BY |
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APPLICANT(S) | Washington University (St. Louis, Missouri) |
ASSIGNEE(S) | |
INVENTOR(S) | Shrihari Sankarasubramanian (St. Louis, Missouri); Vijay Ramani (St. Louis, Missouri) |
ABSTRACT | Described herein is a novel electrode-decoupled redox flow battery, a novel reinforced electrode-decoupled redox flow battery, and methods of using same to store energy. Advantages of these novel electrode-decoupled redox flow batteries include long life, excellent rate capability, and stability. |
FILED | Wednesday, July 07, 2021 |
APPL NO | 17/305422 |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/94 (20130101) H01M 8/188 (20130101) Original (OR) Class H01M 2300/0011 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220013857 | Visco et al. |
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FUNDED BY |
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APPLICANT(S) | PolyPlus Battery Company (Berkeley, California) |
ASSIGNEE(S) | PolyPlus Battery Company (Berkeley, California) |
INVENTOR(S) | Steven J. Visco (Berkeley, California); Yevgeniy S. Nimon (Danville, California); Bruce D. Katz (Moraga, California) |
ABSTRACT | Manufacturing methods for making a substantially rectangular and flat glass preform for manufacturing a Li ion conducting glass separator can involve drawing the preform to a thin sheet and may involve one or more of slumping, rolling or casting the glass within a frame that defines a space filling region and therewith the shape and size of the preform. The thickness of the rectangular flat preform so formed may be about 2 mm or less. The frame may be slotted having a back surface and widthwise wall portion that define the height and width of the space filling region. The flat backing surface and surfaces of the widthwise wall portions are defined may be coated by a material that is inert in direct contact with the heated glass material, such as gold. |
FILED | Tuesday, May 04, 2021 |
APPL NO | 17/302491 |
CURRENT CPC | Manufacture, Shaping, or Supplementary Processes C03B 15/02 (20130101) C03B 19/02 (20130101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 17/22 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0562 (20130101) H01M 50/403 (20210101) Original (OR) Class H01M 50/437 (20210101) H01M 50/449 (20210101) H01M 50/466 (20210101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220014378 | Duncan et al. |
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FUNDED BY |
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APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | |
INVENTOR(S) | Andrew M. Duncan (Oak Ridge, Tennessee); Andrew Harter (Oak Ridge, Tennessee); Charles K. Roberts, II (Oak Ridge, Tennessee); Brad J. Stinson (Oak Ridge, Tennessee); Thad Thompson (Oak Ridge, Tennessee); Bogdan Vacaliuc (Oak Ridge, Tennessee) |
ABSTRACT | A multimodal communication system includes a vehicle controller that controls one or more systems or subsystems of an unmanned vehicle. The communication controller manages communication and logical access to the unmanned vehicle. One or more sensors in communication with the communication controller detects and measures physical properties in proximity to the unmanned vehicle. Transceivers receive the unmanned vehicle commands that are transmitted simultaneously or concurrently and a monotonic generator generates a monotonic object each time the unmanned vehicle's operating state changes. The communication controller executes the first unmanned vehicle command received that has the correct cryptographic hash validating knowledge of the unmanned vehicle's current operating state. |
FILED | Friday, April 23, 2021 |
APPL NO | 17/239067 |
CURRENT CPC | Systems for Controlling or Regulating Non-electric Variables G05D 1/0022 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3236 (20130101) Original (OR) Class Wireless Communication Networks H04W 12/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
US 20220007939 | Dave et al. |
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FUNDED BY |
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APPLICANT(S) | PlenOptika, Inc. (Cambridge, Massachusetts) |
ASSIGNEE(S) | |
INVENTOR(S) | Shivang R. Dave (Boston, Massachusetts); Daryl Lim (Singapore, Singapore); Nicholas James Durr (Baltimore, Maryland) |
ABSTRACT | An apparatus, and corresponding method, for determining a property of an eye includes a housing with a proximal port that receives an eye and also light from the eye. The housing further includes a distal port, and the two ports together form a visual channel providing an open view to enable the eye to see target indicia external to and spaced away from the housing. A wavefront sensor within the housing is configured to receive the light from the eye via the optical path and to measure a wavefront of the light. A determination module determines an objective refractive correction based on the wavefront and predicts a subjective refractive preference of a person having the eye based on the objective refractive correction. Embodiments can be handheld, and binocular, and predict subjective refraction based on demographic and other information. |
FILED | Tuesday, July 20, 2021 |
APPL NO | 17/380891 |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/005 (20130101) A61B 3/0008 (20130101) A61B 3/09 (20130101) A61B 3/18 (20130101) Original (OR) Class A61B 3/028 (20130101) A61B 3/0033 (20130101) A61B 3/103 (20130101) A61B 3/0285 (20130101) A61B 3/1208 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220007943 | Sanchez et al. |
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FUNDED BY |
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APPLICANT(S) | ENSPECTRA HEALTH, INC. (Mountain View, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Gabriel Sanchez (Menlo Park, California); Fred Landavazo, IV (Redwood City, California); Kathryn Montgomery (Mountain View, California); Piyush Arora (San Carlos, California) |
ABSTRACT | Provided herein are methods, devices, and systems that may improve optical resolution when imaging through a thickness of samples. A method for generating a depth profile of a tissue of a subject may comprise using an optical probe to transmit an excitation light beam from a light source towards a surface of the tissue; using one or more focusing units in the optical probe to simultaneously adjust a depth and a position of a focal point of the excitation light beam along a scanning path; detecting at least a subset of the signals generated upon contacting the tissue with the excitation light beam; and using one or more computer processors programmed to process the at least the subset of the signals to generate the depth profile of the tissue. |
FILED | Tuesday, May 11, 2021 |
APPL NO | 17/317661 |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0071 (20130101) A61B 5/0075 (20130101) Original (OR) Class A61B 5/0084 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/10016 (20130101) G06T 2207/10028 (20130101) G06T 2207/30024 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008970 | Quigley et al. |
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FUNDED BY |
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APPLICANT(S) | Loci Controls, Inc. (Fall River, Massachusetts) |
ASSIGNEE(S) | |
INVENTOR(S) | Peter Quigley (Duxbury, Massachusetts); Ian Martin (Sharon, Massachusetts); Jack Rowbottom (Swansea, Massachusetts); Nicole Neff (Colorado Springs, Colorado) |
ABSTRACT | Systems and methods for controlling extraction of landfill gas from a landfill via a gas extraction system are provided herein. According to some aspects of the technology, there is provided site-level control methods for globally controlling one or more wells based on one or more characteristics of aggregate landfill gas collected from a plurality of wells at a gas output. According to some aspects of the technology, there is provided well-level control methods for locally controlling a first well based on or more characteristics of landfill gas collected from the first well. According to further aspects of the technology, there is provided hybrid control methods for making adjustments to a respective well based on both site-level and well-level control methods. |
FILED | Monday, July 13, 2020 |
APPL NO | 16/927471 |
CURRENT CPC | Disposal of Solid Waste B09B 1/006 (20130101) B09B 3/0016 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/123 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008971 | Quigley et al. |
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FUNDED BY |
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APPLICANT(S) | Loci Controls, Inc. (Fall River, Massachusetts) |
ASSIGNEE(S) | |
INVENTOR(S) | Peter Quigley (Duxbury, Massachusetts); Ian Martin (Sharon, Massachusetts); Jack Rowbottom (Swansea, Massachusetts); Nicole Neff (Colorado Springs, Colorado) |
ABSTRACT | Systems and methods for controlling extraction of landfill gas from a landfill via a gas extraction system are provided herein. According to some aspects of the technology, there is provided site-level control methods for globally controlling one or more wells based on one or more characteristics of aggregate landfill gas collected from a plurality of wells at a gas output. According to some aspects of the technology, there is provided well-level control methods for locally controlling a first well based on or more characteristics of landfill gas collected from the first well. According to further aspects of the technology, there is provided hybrid control methods for making adjustments to a respective well based on both site-level and well-level control methods. |
FILED | Monday, July 13, 2020 |
APPL NO | 16/927479 |
CURRENT CPC | Reclamation of Contaminated Soil B09C 1/005 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 34/00 (20130101) E21B 47/06 (20130101) E21B 49/0875 (20200501) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 11/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/004 (20130101) G01N 33/0044 (20130101) G01N 33/0047 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008972 | Quigley et al. |
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FUNDED BY |
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APPLICANT(S) | Loci Controls, Inc. (Fall River, Massachusetts) |
ASSIGNEE(S) | |
INVENTOR(S) | Peter Quigley (Duxbury, Massachusetts); Ian Martin (Sharon, Massachusetts); Jack Rowbottom (Swansea, Massachusetts); Nicole Neff (Colorado Springs, Colorado) |
ABSTRACT | Systems and methods for controlling extraction of landfill gas from a landfill via a gas extraction system are provided herein. According to some aspects of the technology, there is provided site-level control methods for globally controlling one or more wells based on one or more characteristics of aggregate landfill gas collected from a plurality of wells at a gas output. According to some aspects of the technology, there is provided well-level control methods for locally controlling a first well based on or more characteristics of landfill gas collected from the first well. According to further aspects of the technology, there is provided hybrid control methods for making adjustments to a respective well based on both site-level and well-level control methods. |
FILED | Monday, July 13, 2020 |
APPL NO | 16/927482 |
CURRENT CPC | Reclamation of Contaminated Soil B09C 1/005 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 34/00 (20130101) E21B 47/06 (20130101) E21B 49/0875 (20200501) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/004 (20130101) G01N 33/0044 (20130101) G01N 33/0047 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220008973 | Quigley et al. |
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FUNDED BY |
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APPLICANT(S) | Loci Controls, Inc. (Fall River, Massachusetts) |
ASSIGNEE(S) | |
INVENTOR(S) | Peter Quigley (Duxbury, Massachusetts); Ian Martin (Sharon, Massachusetts); Jack Rowbottom (Swansea, Massachusetts); Nicole Neff (Colorado Springs, Colorado) |
ABSTRACT | Systems and methods for controlling extraction of landfill gas from a landfill via a gas extraction system are provided herein. According to some aspects of the technology, there is provided site-level control methods for globally controlling one or more wells based on one or more characteristics of aggregate landfill gas collected from a plurality of wells at a gas output. According to some aspects of the technology, there is provided well-level control methods for locally controlling a first well based on or more characteristics of landfill gas collected from the first well. According to further aspects of the technology, there is provided hybrid control methods for making adjustments to a respective well based on both site-level and well-level control methods. |
FILED | Monday, July 13, 2020 |
APPL NO | 16/927488 |
CURRENT CPC | Reclamation of Contaminated Soil B09C 1/005 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 34/00 (20130101) E21B 47/06 (20130101) E21B 49/0875 (20200501) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/004 (20130101) G01N 33/0044 (20130101) G01N 33/0047 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220009991 | Antipov et al. |
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FUNDED BY |
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APPLICANT(S) | Silver Creek Pharmaceuticals, Inc. (San Francisco, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Laura D.J. Antipov (Oakland, California); Shawdee Eshghi (Oakland, California); Kristopher M. Kuchenbecker (Phoenix, Arizona); Bjorn L. Millard (Orinda, California); Matthew D. Onsum (El Cerrito, California); Andrea D. Nickerson (San Francisco, California); Timothy R. Stowe (San Francisco, California); Yan Zhang (San Francisco, California) |
ABSTRACT | Bi-specific fusion proteins with therapeutic uses are provided, as well as pharmaceutical compositions comprising such fusion proteins, and methods for using such fusion proteins to repair or regenerate damaged or diseased tissue. |
FILED | Tuesday, September 28, 2021 |
APPL NO | 17/487120 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/47 (20130101) C07K 14/65 (20130101) Original (OR) Class C07K 14/765 (20130101) C07K 2319/035 (20130101) C07K 2319/75 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220013767 | YUSHIN et al. |
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FUNDED BY |
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APPLICANT(S) | Sila Nanotechnologies Inc. (Alameda, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Gleb YUSHIN (Atlanta, Georgia); Oleksandr MAGAZYNSKYY (Atlanta, Georgia); Patrick DIXON (Dunwoody, Georgia); Benjamin HERTZBERG (New York, New York) |
ABSTRACT | Described herein are improved composite anodes and lithium-ion batteries made therefrom. Further described are methods of making and using the improved anodes and batteries. In general, the anodes include a porous composite having a plurality of agglomerated nanocomposites. At least one of the plurality of agglomerated nanocomposites is formed from a dendritic particle, which is a three-dimensional, randomly-ordered assembly of nanoparticles of an electrically conducting material and a plurality of discrete non-porous nanoparticles of a non-carbon Group 4A element or mixture thereof disposed on a surface of the dendritic particle. At least one nanocomposite of the plurality of agglomerated nanocomposites has at least a portion of its dendritic particle in electrical communication with at least a portion of a dendritic particle of an adjacent nanocomposite in the plurality of agglomerated nanocomposites. |
FILED | Friday, September 24, 2021 |
APPL NO | 17/484451 |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/133 (20130101) H01M 4/134 (20130101) H01M 4/137 (20130101) H01M 4/366 (20130101) Original (OR) Class H01M 4/587 (20130101) H01M 4/602 (20130101) H01M 4/625 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
US 20220008500 | Kay et al. |
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FUNDED BY |
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APPLICANT(S) | The George Washington University (Washington, District of Columbia); The U.S. Government as represented by The Department of Veterans Affairs (Washington, District of Columbia) |
ASSIGNEE(S) | |
INVENTOR(S) | Matthew Kay (Kensington, Maryland); Kara Garrott (Washington, District of Columbia); Jhansi Dyavanapalli (Gaithersburg, Maryland); David Mendelowitz (Vienna, Virginia); Gregory Trachiotis (Arlington, Virginia) |
ABSTRACT | Methods of treating a subject having heart failure including heart failure with reduced ejection fraction, heart failure with preserved ejection fraction, and left ventricular hypertrophy-induced heart failure. The methods include activating hypothalamic oxytocin neurons in the brain of the subject and/or administering intranasally to the subject a therapeutically effective amount of oxytocin. Intranasal formulations for the treatment of a subject diagnosed with heart failure are also provided. |
FILED | Wednesday, June 16, 2021 |
APPL NO | 17/349771 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0043 (20130101) A61K 38/095 (20190101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220010269 | Cullen et al. |
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FUNDED BY |
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APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
ASSIGNEE(S) | |
INVENTOR(S) | Daniel Kacy Cullen (Media, Pennsylvania); Suradip Das (Philadelphia, Pennsylvania); Wisberty Gordian-Velez (Philadelphia, Pennsylvania) |
ABSTRACT | In various aspects and embodiments, the present invention provides methods for preparing innervated tissue. In various embodiments the invention further provides innervated tissue generated using the methods described herein. In various embodiments the inclusion of optogenetically transducible TENGs or Micro-TENNs in the innervated tissue allows the modulation of tissue or organs by using light to stimulate the optogenetically transducible TENGs or Micro-TENNs. |
FILED | Friday, November 08, 2019 |
APPL NO | 17/291869 |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/34 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) Original (OR) Class C12N 5/0619 (20130101) C12N 5/0633 (20130101) C12N 5/0648 (20130101) C12N 5/0657 (20130101) C12N 5/0658 (20130101) C12N 5/0677 (20130101) C12N 5/0679 (20130101) C12N 5/0685 (20130101) C12N 2502/081 (20130101) C12N 2513/00 (20130101) C12N 2533/76 (20130101) C12N 2533/80 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220012902 | Madabhushi et al. |
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FUNDED BY |
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APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
ASSIGNEE(S) | |
INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Jacob Antunes (Cincinnati, Ohio); Zhouping Wei (Cleveland, Ohio); Pallavi Tiwari (Wexford, Pennsylvania); Satish E. Viswanath (Pepper Pike, Ohio); Charlems Alvarez Jimenez (Bogotá, Colombia) |
ABSTRACT | The present disclosure, in some embodiments, relates to a non-transitory computer-readable medium storing computer-executable instructions. The computer readable medium is configured to cause a processor to access an image volume of a rectum comprising a rectal tumor. A forward mapping is generated based on non-rigidly registering a healthy rectal atlas to the image volume. The forward mapping is inverted to generate an inverse mapping from the image volume to the healthy rectal atlas. Based on the inverse mapping, a plurality of deformation vectors, associated with a deformation within a rectal wall of the rectum, are determined. Magnitude based deformation features and orientation based deformation features are computed from the plurality of deformation vectors. One or more of the magnitude based deformation features and one or more of the orientation based deformation features are utilized to determine a response of a patient to a chemoradiation treatment. |
FILED | Wednesday, September 22, 2021 |
APPL NO | 17/481625 |
CURRENT CPC | Image Data Processing or Generation, in General G06T 7/33 (20170101) Original (OR) Class G06T 7/38 (20170101) G06T 2207/10088 (20130101) G06T 2207/30096 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/40 (20180101) G16H 50/70 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 20220011179 | RYU |
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FUNDED BY |
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APPLICANT(S) | New Mexico Tech University Research Park Corporation (Socorro, New Mexico) |
ASSIGNEE(S) | |
INVENTOR(S) | Donghyeon RYU (Socorro, New Mexico) |
ABSTRACT | Disclosed herein is a composition and a method for energy harvesting and the autonomous detection of structural failure. This method can be used to monitor, for example, the structural integrity of unmanned aircraft systems. |
FILED | Monday, May 17, 2021 |
APPL NO | 17/321830 |
CURRENT CPC | Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 5/60 (20170101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/24 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/082 (20130101) H01L 41/193 (20130101) H01L 41/1132 (20130101) H01L 51/004 (20130101) H01L 51/0035 (20130101) H01L 51/0036 (20130101) H01L 51/0037 (20130101) H01L 51/0047 (20130101) H01L 51/0048 (20130101) H01L 51/0094 (20130101) H01L 51/5287 (20130101) Electric Machines Not Otherwise Provided for H02N 2/186 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220013706 | Greer et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Harold Frank Greer (Pasadena, California); Andrew D. Beyer (Pasadena, California); Matthew D. Shaw (Pasadena, California); Daniel P. Cunnane (Pasadena, California) |
ABSTRACT | A method for etching a surface including obtaining a structure comprising a plurality of nanowires on or above a substrate and a dielectric layer on or above the nanowires, wherein the dielectric layer comprises protrusions formed by the underlying nanowires; reacting a surface of the dielectric layer with a reactant, comprising a gas or a plasma, to form a reactive layer on the dielectric layer, wherein the reactive layer comprises a chemical compound including the reactant and elements of the dielectric layer and the reactive layer comprises sidewalls defined by the protrusions; and selectively etching the reactive layer, wherein the etching etches the protrusions laterally through the sidewalls so as to planarize the surface and remove or shrink the protrusions. |
FILED | Monday, July 12, 2021 |
APPL NO | 17/373619 |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/08 (20130101) H01L 39/24 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220013767 | YUSHIN et al. |
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FUNDED BY |
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APPLICANT(S) | Sila Nanotechnologies Inc. (Alameda, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Gleb YUSHIN (Atlanta, Georgia); Oleksandr MAGAZYNSKYY (Atlanta, Georgia); Patrick DIXON (Dunwoody, Georgia); Benjamin HERTZBERG (New York, New York) |
ABSTRACT | Described herein are improved composite anodes and lithium-ion batteries made therefrom. Further described are methods of making and using the improved anodes and batteries. In general, the anodes include a porous composite having a plurality of agglomerated nanocomposites. At least one of the plurality of agglomerated nanocomposites is formed from a dendritic particle, which is a three-dimensional, randomly-ordered assembly of nanoparticles of an electrically conducting material and a plurality of discrete non-porous nanoparticles of a non-carbon Group 4A element or mixture thereof disposed on a surface of the dendritic particle. At least one nanocomposite of the plurality of agglomerated nanocomposites has at least a portion of its dendritic particle in electrical communication with at least a portion of a dendritic particle of an adjacent nanocomposite in the plurality of agglomerated nanocomposites. |
FILED | Friday, September 24, 2021 |
APPL NO | 17/484451 |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/133 (20130101) H01M 4/134 (20130101) H01M 4/137 (20130101) H01M 4/366 (20130101) Original (OR) Class H01M 4/587 (20130101) H01M 4/602 (20130101) H01M 4/625 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 20220007608 | Hankoua et al. |
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FUNDED BY |
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APPLICANT(S) | Bertrand B. Hankoua (Dover, Delaware); Ayalew Ligaba Osena (Dover, Delaware) |
ASSIGNEE(S) | Delaware State University (Dover, Delaware) |
INVENTOR(S) | Bertrand B. Hankoua (Dover, Delaware); Ayalew Ligaba Osena (Dover, Delaware) |
ABSTRACT | The present invention provides a longitudinally split immature tiller separated from a rhizome (LSITR), a cluster of multiple in vitro shoots (CMIT), a cluster of stem segments containing shoot primordia (CSSSP) and an in vitro tiller of Miscanthus x giganteus (Giant Miscanthus), and their uses in propagating Miscanthus x giganteus (Giant Miscanthus). |
FILED | Thursday, September 23, 2021 |
APPL NO | 17/482723 |
CURRENT CPC | Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 20/00 (20180201) New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 4/005 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220007652 | SMITH et al. |
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FUNDED BY |
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APPLICANT(S) | Mississippi State University (Starkville, Mississippi); The Texas A and M University System (College Station, Texas) |
ASSIGNEE(S) | Mississippi State University (Starkville, Mississippi); The Texas A and M University System (College Station, Texas) |
INVENTOR(S) | JAMES LEIF SMITH (COLLEGE STATION, Texas); AKSHAYA RAVICHANDRAN (COLLEGE STATION, Texas); SHIEN LU (STARKVILLE, Mississippi); GANYU GU (PAINTER, Virginia) |
ABSTRACT | Occidiofungin is a cyclic nonribosomally synthesized antifungal peptide with submicromolar activity. This invention is directed to compositions enriched for particular occidiofungin diastereomers/conformers, methods of making compositions enriched for particular diastereomers/conformers and microorganisms suitable for producing enriched compositions of particular diastereomers/conformers. Methods of treating fungal infections or plants infected by fungi are also provided. |
FILED | Monday, December 07, 2020 |
APPL NO | 17/113764 |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 43/713 (20130101) A01N 63/50 (20200101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 38/12 (20130101) Peptides C07K 7/54 (20130101) C07K 7/56 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Enzymes C12Y 301/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
US 20220012752 | Ellison et al. |
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FUNDED BY |
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APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
INVENTOR(S) | Chang Ellison (Arlington, Virginia); Kelli L. Biegger (McLean, Virginia); Daniel A. Boyd (Arlington, Virginia); Brandon P. Gutierrez (Burke, Virginia); Jason Lim (Alexandria, Virginia) |
ABSTRACT | In an example, a subject using a user mobile-identification-credential device (UMD) requests vetting by a vetting system, which receives verified subject information associated with a level-n mobile identification credential (MIC-n) that UMD received from a level-n authorizing party system (APS-n). MIC-n is linked to lower level MIC-0 to MIC-(n−1). The vetting system, as level-n relying party system (RPS-n), uses the verified subject information associated with the linked MIC-0 to MIC-n to verify or not verify the identity of the subject, develops an identity profile of the subject, and determines a vetting result of the subject by calculating a composite trust score based on MIC trust values for the multiple levels of MIC. MIC-i (i=1 to n) is linked to MIC-(i−1) which UMD received from APS-(i−1), and APS-i is RPS-(i−1) which verified the identity of the subject using verified subject information associated with MIC-(i−1), such that MIC-0 to MIC-n are linked. |
FILED | Thursday, July 22, 2021 |
APPL NO | 17/383151 |
CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 30/018 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3213 (20130101) Wireless Communication Networks H04W 12/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 20220014907 | Boyd et al. |
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FUNDED BY |
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APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
INVENTOR(S) | Daniel A. Boyd (Arlington, Virginia); Kelli L. Biegger (McLean, Virginia); Chang Ellison (Arlington, Virginia); Brandon P. Gutierrez (Burke, Virginia); Jason Lim (Alexandria, Virginia); William Washington (North Potomac, Maryland) |
ABSTRACT | A stopped vehicle information remote retrieval method includes an emergency personnel or first responder vehicle (FRV) establishing a vehicle connection between an infotainment system of a stopped vehicle and the FRV. The FRV sends a vehicle information request to the infotainment system of the stopped vehicle, via the vehicle connection, seeking release of vehicle information. The FRV obtains authentication of the vehicle information received in response to the vehicle information request. The FRV determines occupant status based on the vehicle information. The FRV communicates the passenger status to a first responder. |
FILED | Friday, February 19, 2021 |
APPL NO | 17/180334 |
CURRENT CPC | Wireless Communication Networks H04W 4/46 (20180201) H04W 12/02 (20130101) H04W 12/04 (20130101) Original (OR) Class H04W 12/033 (20210101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
US 20220009834 | Fatmehsari et al. |
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FUNDED BY |
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APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska) |
INVENTOR(S) | Hamzeh Haghshenas Fatmehsari (Lincoln, Nebraska); Robert Rea (Ashland, Nebraska) |
ABSTRACT | An asphalt pavement modification system and method for improving aging resistance of asphalt pavement and a method of manufacturing reclaimed asphalt pavement. The asphalt pavement modification system and method include using one or more antioxidants and one or more recycling agents in a blended binder to provide improved short term and long term performance of the asphalt pavement. The method of manufacturing reclaimed asphalt pavement includes mixing at least one antioxidant with at least one recycling agent to form a binder that constitutes a portion of the reclaimed asphalt pavement. One of the antioxidants may be zinc diethyldithiocarbamate. |
FILED | Friday, July 09, 2021 |
APPL NO | 17/371478 |
CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 26/003 (20130101) Original (OR) Class C04B 26/26 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
US 20220012911 | TOWNSEND et al. |
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FUNDED BY |
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APPLICANT(S) | UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
ASSIGNEE(S) | |
INVENTOR(S) | Andrew TOWNSEND (Clifton, Virginia); David LIN (Merrifield, Virginia); Barry E. RUSSELL (Falls Church, Virginia); Roger WORNER (Saint Peters, Missouri) |
ABSTRACT | A computer-implemented system, method and computer-program product are configured to receive an image of a location from at least one image sensor device; analyze the image to determine a distance between a person and an object in the image; and output a control signal when the determined distance between the person and the object is below a predetermined threshold distance. The control signal causes an electronic device at the location to perform an action related to the distance between the person and the object. The object may be another person. |
FILED | Tuesday, July 13, 2021 |
APPL NO | 17/373847 |
CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 15/02 (20130101) Image Data Processing or Generation, in General G06T 7/74 (20170101) Original (OR) Class G06T 2207/30196 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/182 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 20220009633 | Budd et al. |
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FUNDED BY |
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APPLICANT(S) | Sky Launch Corporation (Lancaster, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Gerald D. Budd (Lancaster, California); Charles E. Rogers (Lancaster, California) |
ABSTRACT | Embodiments of a system and method for carrying an aeronautical or launch vehicle to altitude for release to flight are disclosed. The system may comprise a multiplicity of mounting elements configured to be affixed to a carrier aircraft in distributed fashion along a mounting axis. Each mounting element may include a cradle and a retention strap. Each retention strap may be suspendedly attached to a respective said cradle, and actuatable from a retention configuration to a release configuration. The retention configuration may enable the retention straps to clampingly secure the vehicle to the respective cradles. The actuation of the retention straps from the retention configuration to the release configuration may disable the clamping securement and thereby release the vehicle to drop away from the cradles. For one or more of the retention straps, the actuation may be by way of detonating at least one corresponding pyrotechnic fastener. |
FILED | Friday, July 09, 2021 |
APPL NO | 17/372388 |
CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 1/02 (20130101) B64D 5/00 (20130101) Original (OR) Class B64D 27/023 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 3/006 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, January 13, 2022.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2021/details-patents-20210427.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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