FedInvent™ Patent Applications
Application Details for Thursday, March 10, 2022
This page was updated on Friday, March 11, 2022 at 04:34 PM GMT
Department of Health and Human Services (HHS)
| US 20220071501 | Clark et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Robert Clark (Pittsburgh, Pennsylvania); Gilles Clermont (Fombell, Pennsylvania); Michael Wolf (Nashville, Tennessee) |
| ABSTRACT | System for monitoring intracranial compliance in a patient includes an intracranial pressure sensor, configured to obtain a measurement indicative of an intracranial pressure of a patient, a CO2 sensor, configured to obtain a measurement indicative of a CO2 level of the patient, and a processor, configured to determine an intracranial compliance from the measurements indicative of the intracranial pressure and the CO2 level. Methods for monitoring intracranial compliance in a patient are also provided. |
| FILED | Friday, November 12, 2021 |
| APPL NO | 17/524791 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/031 (20130101) Original (OR) Class A61B 5/746 (20130101) A61B 5/6868 (20130101) A61B 2562/0247 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220071537 | Negi et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sandeep Negi (Salt Lake City, Utah); Rajmohan Bhandari (Salt Lake City, Utah) |
| ABSTRACT | A method of manufacturing a micro-molded electrode having multiple individually addressable sensors along a shaft can include forming a recess in a mold substrate, depositing a structural material therein, depositing a conductive material at specific locations, providing a coating, and removing the mold substrate. A micro-molded electrode having a base tapering to at least one shaft can include an electrode substrate, multiple individually addressable sensors, and a coating. |
| FILED | Wednesday, November 17, 2021 |
| APPL NO | 17/528853 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/24 (20210101) Original (OR) Class A61B 5/291 (20210101) A61B 5/296 (20210101) A61B 5/389 (20210101) A61B 5/685 (20130101) A61B 5/4029 (20130101) A61B 5/4058 (20130101) A61B 2562/125 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0551 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220071549 | Verkman et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alan S. Verkman (San Francisco, California); Julie M. Shallhorn (San Francisco, California); Neel D. Pasricha (San Francisco, California); Marc H. Levin (San Carlos, California) |
| ABSTRACT | The disclosed apparatus, systems and methods relate to ocular surface potential difference (OSPD) measurement, and in particular, to the devices, methods, and design principles allowing for such measurement and the use of the measured OSPD in various research and clinical settings. |
| FILED | Wednesday, September 08, 2021 |
| APPL NO | 17/469282 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/101 (20130101) A61B 5/398 (20210101) Original (OR) Class A61B 5/0538 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220071613 | Rege et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kaushal Rege (Gilbert, Arizona); Ridha Inam (Tempe, Arizona); Yu Yao (Chandler, Arizona) |
| ABSTRACT | A method of closing an opening in a tissue comprises providing a light absorbing material, introducing the light absorbing material into a tissue opening, and irradiating the light absorbing material with at least one light source so as to increase a temperature of the light absorbing material, causing the tissue edges of the tissue opening adhere to the light absorbing material and/or to each other. A kit comprising a light absorbing material and a light emitting device is also described. |
| FILED | Thursday, December 19, 2019 |
| APPL NO | 17/416240 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/00491 (20130101) Original (OR) Class A61B 2017/00508 (20130101) A61B 2018/00452 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 17/08 (20130101) A61L 17/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220071705 | Yang et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Kansas (Lawrence, Kansas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xinmai Yang (Lawrence, Kansas); M Laird Forrest (Lawrence, Kansas) |
| ABSTRACT | A system for thrombolysis includes an optical energy source, an ultrasound transducer, and an optical conduit for insertion into a vessel. The optical conduit directs optical energy from the optical energy source to a target location at a terminal end of the optical conduit. |
| FILED | Friday, September 03, 2021 |
| APPL NO | 17/466780 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/245 (20130101) Original (OR) Class A61B 2018/00994 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/013 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220071903 | GAO et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Jinming GAO (Dallas, Texas); Suxin LI (Dallas, Texas) |
| ABSTRACT | Described herein are therapeutic pH responsive compositions useful for the treatment of cancer. The compositions involve combining a STING activating polymer micelle, such as PC7A, with a non-peptide STING agonist, such as cGAMP. Methods of administering these compositions in the treatment of cancer are also disclosed. These methods include administration of the pharmaceutical compositions by intratumoral injection in the treatment of solid tumors. |
| FILED | Wednesday, September 08, 2021 |
| APPL NO | 17/469111 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) Original (OR) Class A61K 31/4184 (20130101) A61K 31/5377 (20130101) A61K 31/7076 (20130101) A61K 47/32 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220071906 | Yantasee et al. |
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| FUNDED BY |
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| APPLICANT(S) | Oregon Health and Science University (Portland, Oregon); PDX Pharmaceuticals, Inc. (Portland, Oregon) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon); PDX Pharmaceuticals, Inc. (Portland, Oregon) |
| INVENTOR(S) | Wassana Yantasee (Lake Oswego, Oregon); Moataz Reda (Portland, Oregon); Worapol Ngamcherdtrakul (Portland, Oregon) |
| ABSTRACT | Disclosed herein are therapeutic constructs including a delivery particle, at least one mitotic kinase inhibitor, and at least one immune checkpoint inhibitor. Also disclosed are therapeutic constructs including a mitotic kinase inhibitor, an immune checkpoint inhibitor, and a chemical linker. These therapeutic constructs cause cancer death by both therapeutic and immune effects and promote targeted delivery of more therapeutics to the surviving cancer cells in a positive feed-back loop. They enhance therapeutic index of free drugs and can be used intratumorally or systemically. This strategy can treat broad cancer types and is particular useful for cancer without obvious receptors for cancer-targeted delivery of otherwise toxic therapeutics. |
| FILED | Tuesday, November 23, 2021 |
| APPL NO | 17/534415 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/143 (20130101) Original (OR) Class A61K 9/146 (20130101) A61K 31/519 (20130101) A61K 47/6803 (20170801) A61K 47/6849 (20170801) Peptides C07K 16/2827 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220071923 | Kannan et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland); Kennedy Krieger Institute, Inc. (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sujatha Kannan (Baltimore, Maryland); Seyed Ali Fatemi (Baltimore, Maryland); Kannan Rangaramanujam (Baltimore, Maryland); Fan Zhang (Baltimore, Maryland); Bela Turk (Baltimore, Maryland); Ozgul Gok (Baltimore, Maryland) |
| ABSTRACT | Compositions and methods for treating, alleviating, and/or preventing one or more symptoms associated with axonal degeneration in individuals in need thereof, such as individuals with peroxisomal disorders and leukodystrophies include one or more poly(amidoamine) dendrimers G1-G10, preferably G4-G6, complexed with therapeutic, prophylactic and/or diagnostic agent in an effective amount to treat, and/or prevent one or more symptoms associated with axonal degeneration are provided. Compositions are particularly suited for targeted delivery of therapeutics to the affected spinal neurons and may contain one or more additional targeting moieties. |
| FILED | Monday, September 20, 2021 |
| APPL NO | 17/479400 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/05 (20130101) Original (OR) Class A61K 31/192 (20130101) A61K 31/195 (20130101) A61K 31/573 (20130101) A61K 47/60 (20170801) A61K 47/595 (20170801) A61K 49/0004 (20130101) A61K 49/0032 (20130101) A61K 49/0054 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220071928 | PHANSTIEL, IV et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida); TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Otto PHANSTIEL, IV (Orlando, Florida); John CONNOR (Boston, Massachusetts) |
| ABSTRACT | Disclosed herein are polyamine transport inhibitors (PTI) and methods of use as antivirals. Disclosed PTI compounds are useful as treatments for viral infections or can be used as prophylactic agents that protect high risk individuals from becoming infected by the virus. The disclosed PTI compounds can be used alone or in combination with other agents (or other antivirals) to improve patient outcomes such as DFMO (or Remdesivir). |
| FILED | Wednesday, September 08, 2021 |
| APPL NO | 17/469827 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/13 (20130101) A61K 31/16 (20130101) A61K 31/132 (20130101) Original (OR) Class A61K 31/155 (20130101) A61K 31/198 (20130101) A61K 31/404 (20130101) A61K 31/505 (20130101) A61K 31/513 (20130101) A61K 31/522 (20130101) A61K 31/675 (20130101) A61K 31/4706 (20130101) A61K 31/4985 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/12 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220071981 | Blobel et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (Philadelphia, Pennsylvania); THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); COLD SPRING HARBOR LABORATORY (Cold Spring Harbor, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gerd Blobel (Bala Cynwyd, Pennsylvania); Jeremy Grevet (Philadelphia, Pennsylvania); Junwei Shi (Philadelphia, Pennsylvania); Christopher Vakoc (Cold Spring Harbor, New York) |
| ABSTRACT | Methods and compositions for producing fetal hemoglobin and treating a hemoglobinopathy or thalassemia are disclosed. |
| FILED | Monday, November 22, 2021 |
| APPL NO | 17/532123 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/454 (20130101) Original (OR) Class A61K 31/517 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/06 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220071995 | De Waal et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); Bayer Pharma Aktiengesellschaft (Berlin, Germany) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); Bayer Pharma Aktiengesellschaft (Berlin, Germany) |
| INVENTOR(S) | Luc De Waal (Boston, Massachusetts); Matthew Meyerson (Boston, Massachusetts); Heidi Greulich (Boston, Massachusetts); Monica Schenone (Cambridge, Massachusetts); Alex Burgin (Cambridge, Massachusetts); Xiaoyun Wu (Cambridge, Massachusetts); Ulrike Sack (Monheim Am Rhein, Germany) |
| ABSTRACT | The present invention features improved methods of identifying patients having cancer (e.g., melanoma, adenocarcinoma, lung, cervical, liver or breast cancer) using biomarkers (e.g., PDE3A, SLFN12) that correlate with drug sensitivity and consequently treating a stratified patient population with an agent of the invention (e.g., DNMDP, zardaverine, and anagrelide). |
| FILED | Thursday, November 18, 2021 |
| APPL NO | 17/530402 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 31/50 (20130101) Original (OR) Class A61K 31/519 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57488 (20130101) G01N 2333/916 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220071999 | MILLER et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF NOTRE DAME DU LAC (SOUTH BEND, Indiana); MONTANA STATE UNIVERSITY (BOZEMAN, Montana); NANYANG TECHNOLOGICAL UNIVERSITY (Singapore, Singapore) |
| ASSIGNEE(S) | UNIVERSITY OF NOTRE DAME DU LAC (SOUTH BEND, Indiana); MONTANA STATE UNIVERSITY (BOZEMAN, Montana); NANYANG TECHNOLOGICAL UNIVERSITY (SINGAPORE, Singapore) |
| INVENTOR(S) | Marvin J. MILLER (South Bend, Indiana); Garrett C. MORASKI (Bozeman, Montana); Kevin PETHE (Singapore, Singapore) |
| ABSTRACT | Described are compounds and compositions that inhibit or target Cyt-bd, and methods of making, using, and assaying same. Also disclosed are compositions, methods and kits including the compounds and compositions that inhibit or target Cyt-bd, and one or more Cyt-bc1:aa3 inhibitor, F1F0-ATP synthase inhibitor, NADH dehydrogenase (NDH-2) inhibitor, NADH dehydrogenase (NDH-2) activator or antibacterial agent. |
| FILED | Thursday, December 19, 2019 |
| APPL NO | 17/416016 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/517 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Heterocyclic Compounds C07D 239/94 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072006 | Reitz et al. |
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| FUNDED BY |
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| APPLICANT(S) | Biohaven Pharmaceutical Holding Company Limited (B (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Allen B. Reitz (Lansdale, Pennsylvania); Garry Robert Smith (Royersford, Pennsylvania) |
| ABSTRACT | Pharmaceutical compositions of the invention include substituted riluzole pro drugs useful for the treatment of amyotrophic lateral sclerosis (ALS) and related disorders through the release of riluzole, especially to avoid patient to patient variability in first pass, hepatic metabolism promoted by Cyp 1A2. Pro-drugs of riluzole have enhanced stability to hepatic metabolism and are delivered into systemic circulation by oral administration, and then cleaved to release riluzole in the plasma via either an enzymatic or general biophysical release process. The invention further includes pro-drugs of riluzole useful for the treatment of disease states that can be treated with riluzole through the release of riluzole from a pro-drug agent. |
| FILED | Tuesday, November 16, 2021 |
| APPL NO | 17/527428 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/428 (20130101) A61K 31/454 (20130101) A61K 31/496 (20130101) A61K 31/541 (20130101) Original (OR) Class A61K 31/4439 (20130101) A61K 31/4725 (20130101) A61K 31/5377 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072023 | Moon et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James J. Moon (Ann Arbor, Michigan); Xiaoqi Sun (Ann Arbor, Michigan) |
| ABSTRACT | This disclosure provides compositions and methods for stimulating the innate immune response in a subject with agents capable of stimulating an innate immune response in a subject upon administration to the subject (e.g., damage-associated molecular patterns (DAMPs) and pathogen-associated molecular patterns (PAMPs)). In particular, the present invention is directed to compositions of DAMPs/PAMPs and metals ions, as well as systems and methods utilizing such nanoparticles (e.g., in diagnostic and/or therapeutic settings). |
| FILED | Friday, July 12, 2019 |
| APPL NO | 17/259819 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1271 (20130101) A61K 9/1611 (20130101) A61K 9/1641 (20130101) A61K 31/42 (20130101) A61K 31/52 (20130101) A61K 31/167 (20130101) A61K 31/192 (20130101) A61K 31/196 (20130101) A61K 31/198 (20130101) A61K 31/353 (20130101) A61K 31/366 (20130101) A61K 31/395 (20130101) A61K 31/409 (20130101) A61K 31/519 (20130101) A61K 31/573 (20130101) A61K 31/655 (20130101) A61K 31/4745 (20130101) A61K 31/5415 (20130101) A61K 31/7034 (20130101) A61K 31/7048 (20130101) A61K 31/7068 (20130101) A61K 31/7084 (20130101) Original (OR) Class A61K 33/242 (20190101) A61K 38/2006 (20130101) A61K 39/0008 (20130101) A61K 39/39 (20130101) A61K 39/00116 (20180801) A61K 39/001106 (20180801) A61K 39/001109 (20180801) A61K 39/001156 (20180801) A61K 39/001157 (20180801) A61K 39/001182 (20180801) A61K 39/001184 (20180801) A61K 39/001186 (20180801) A61K 39/001197 (20180801) A61K 39/001198 (20180801) A61K 39/3955 (20130101) A61K 47/6915 (20170801) A61K 2039/60 (20130101) A61K 2039/55505 (20130101) A61K 2039/55511 (20130101) A61K 2039/55516 (20130101) A61K 2039/55522 (20130101) A61K 2039/55533 (20130101) A61K 2039/55544 (20130101) A61K 2039/55555 (20130101) A61K 2039/55561 (20130101) A61K 2039/55572 (20130101) A61K 2039/55577 (20130101) A61K 2039/55583 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072041 | COOPER et al. |
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| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Laurence J.N. COOPER (Houston, Texas); Harjeet SINGH (Houston, Texas); Helen HULS (Houston, Texas); Simon OLIVARES (Houston, Texas); Bipulendu JENA (Houston, Texas); Krina PATEL (Houston, Texas) |
| ABSTRACT | Chimeric antigen receptor (CAR) polypeptides (and immune effector cells expressing the CARs) are provided comprising modified hinge domain sequences. Also provided are engineered antigen presenting cells (APCs) that express transgenes encoding target antigen and human leukocyte antigen (HLA). In further aspect, immune effector cells are provided that have been selected for elevated mitochondrial spare respiratory capacity. |
| FILED | Friday, July 09, 2021 |
| APPL NO | 17/371924 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 39/0011 (20130101) A61K 2039/5154 (20130101) A61K 2039/5156 (20130101) Peptides C07K 14/7051 (20130101) C07K 16/30 (20130101) C07K 16/2803 (20130101) C07K 2317/53 (20130101) C07K 2317/71 (20130101) C07K 2317/622 (20130101) C07K 2319/00 (20130101) C07K 2319/03 (20130101) C07K 2319/33 (20130101) C07K 2319/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072062 | Marban et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eduardo Marban (Santa Monica, California); Mark Amin Aminzadeh (Los Angeles, California) |
| ABSTRACT | Described herein are compositions and techniques related to generation and therapeutic application of cardiosphere-derived cells (CDCs) and CDC-derived exosomes. These cells and their secreted vesicles contain a unique milieu of biological factors, including cytokines, growth factors, transcription factors, nucleic acids including non-coding nucleic acids such as microRNAs, that serve to initiate and promote many therapeutic effects. Exosomes and their “cargo” contents, such as microRNAs can favorably modulate apoptosis, inflammation and fibrosis in the injured heart. Thus, CDC-derived exosomes represent a novel “cellfree” therapeutic candidate for tissue repair. |
| FILED | Wednesday, November 17, 2021 |
| APPL NO | 17/528822 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/713 (20130101) A61K 35/34 (20130101) Original (OR) Class A61K 38/1709 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) A61P 21/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/141 (20130101) C12N 2320/31 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072065 | Bailey et al. |
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| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Antoinette Bailey (Pasadena, California); Sarkis K. Mazmanian (Porter Ranch, California); Paul H. Patterson (Altadena, California) |
| ABSTRACT | Some embodiments include bacterial species for use in treatment of one or more autism spectrum disorder (ASD), and/or schizophrenia symptoms in a subject in need thereof. The subject in need thereof can have a gut microbiota signature characteristic of an adult. The bacterial species can include Bacteroides (e.g., B. fragilis, B. thetaiotaomicron, and/or B. vulgatus), and/or Enterococcus (e.g., E. faecalis, E. faecium, E. hirae, E. avium, E. durans, E. gallinarum, or E. casseliflavus). Upon treatment, one or more ASD-related behaviors can be improved in the subject. |
| FILED | Thursday, November 18, 2021 |
| APPL NO | 17/455578 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) A61K 35/741 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
20220072088 — REDUCING CLOSTRIDIUM PERFRINGENS VIRULENCE USING INHIBITORS OF AGR-LIKE QUORUM SENSING
| US 20220072088 | Uzal et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Francisco Uzal (San Bernardino, California); Mauricio Andres Navarro Badilla (San Bernardino, California); Bruce McClane (Pittsburgh, Pennsylvania); Jihong Li (Pittsburgh, Pennsylvania) |
| ABSTRACT | This disclosure provides materials and methods for reducing production of virulence factors in C. perfringens and or other pathogenic clostridia with related Agr-like QS systems using compounds that interfere with the Agr-like quorum sensing (QS) system. For example, Agr-like QS system inhibitors based on peptidomimetic compounds of the Agr-like QS system signaling peptide (SP) or the SP receptor of C. perfringens, and methods of using the Agr-like QS system inhibitors to prevent, treat, or ameliorate a disease associated with C. perfringens infection are provided. |
| FILED | Thursday, September 09, 2021 |
| APPL NO | 17/470775 |
| CURRENT CPC | Fodder A23K 20/147 (20160501) A23K 20/195 (20160501) A23K 50/50 (20160501) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/18 (20160801) A23L 33/127 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/10 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072092 | Schultz et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| ASSIGNEE(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| INVENTOR(S) | Michael K. Schultz (Iowa City, Iowa); Frances L. Johnson (Iowa City, Iowa); Somya Kapoor (Iowa City, Iowa); Dongyoul Lee (Iowa City, Iowa); Mengshi Li (Iowa City, Iowa); Molly Martin (Iowa City, Iowa) |
| ABSTRACT | The invention provides compositions, kits and methods to treat a hyperproliferative disorder with an agent that increases expression of MCR1 and an MCR1 ligand. The invention also provides a method of treating drug-resistant melanoma, comprising administering an MCR1 ligand to a patient in need thereof. The present invention also provides in certain embodiments a melanoma-targeting conjugate comprising Formula I. T-L-X wherein T is a MCR1 ligand, L is a linker, and X an anti-cancer composition, for the therapeutic treatment of a hyperproliferative disorder. The present invention also provides methods, kits, and uses of the conjugate of Formula I. |
| FILED | Friday, November 19, 2021 |
| APPL NO | 17/531485 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/12 (20130101) Original (OR) Class A61K 47/60 (20170801) A61K 47/547 (20170801) A61K 51/0482 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2818 (20130101) C07K 16/2827 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072094 | McNamara et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James O. McNamara (Durham, North Carolina); Xiao-Ping He (Durham, North Carolina); Yangzhong Huang (Durham, North Carolina); Bin Gu (Durham, North Carolina) |
| ABSTRACT | The invention provides pharmaceutical compositions and methods of use thereof for preventing or ameliorating disorders of the nervous system. More specifically, the invention provides pharmaceutical compositions, including phosphopeptides that when administered disrupt the physical interaction of TrkB with its signaling effector, phospholipase Cγ1 (PLCγ1). The invention further provides method of treatment comprising administering phosphopeptides that uncouple TrkB from PLCγ1 in order to prevent and/or ameliorate nervous system disorders such as epilepsy, anxiety, and seizures. |
| FILED | Monday, September 27, 2021 |
| APPL NO | 17/485850 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) A61K 38/04 (20130101) A61K 38/16 (20130101) Original (OR) Class A61K 45/06 (20130101) Peptides C07K 16/2863 (20130101) C07K 2317/33 (20130101) C07K 2317/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072115 | Michelow et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rhode Island Hospital (Providence, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ian Charles Michelow (Needham, Massachusetts); Jonathan Kurtis (Providence, Rhode Island) |
| ABSTRACT | Provided herein are compositions and methods for treating and preventing malaria. The vaccine of the invention is directed to the protein encoded by the PF3D7_1134300 gene, or fragments of the protein, which are Pf Erythrocyte Membrane and Merozoite Antigenl (PfEMMAI). Exemplary fragments include Fragment 1, Fragment 2, or a C-terminal fragment of PfEMMAI. |
| FILED | Monday, November 04, 2019 |
| APPL NO | 17/289133 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/015 (20130101) Original (OR) Class A61K 2039/545 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 33/06 (20180101) A61P 37/04 (20180101) Peptides C07K 16/205 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072119 | Khurana |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human (Silver Spring, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human (Silver Spring, Maryland) |
| INVENTOR(S) | Surender Khurana (Clarksburg, Maryland) |
| ABSTRACT | Isolated peptides comprising one or more antigenic sites of filovirus glycoprotein and methods of their use and production are disclosed. Nucleic acid molecules encoding the peptides are also provided. In several embodiments, the peptides can be used to induce an immune response to filovirus glycoprotein, such as Zaire ebolavirus glycoprotein, in a subject, for example, to treat or prevent infection of the subject with the virus. |
| FILED | Tuesday, November 16, 2021 |
| APPL NO | 17/527968 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/6081 (20130101) Peptides C07K 14/005 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072120 | Kanekiyo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The USA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); Unversity of Washington (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Masaru Kanekiyo (Bethesda, Maryland); Barney S. Graham (Rockville, Maryland); Seyhan Boyoglu-Barnum (Rockville, Maryland); Rebecca A. Gillespie (Bethesda, Maryland); Neil P. King (Seattle, Washington); Daniel Ellis (Seattle, Washington); Jing Yang Wang (Seattle, Washington); George Ueda (Seattle, Washington); Jorge Fallas (Seattle, Washington) |
| ABSTRACT | Nanoparticles and vaccines containing these nano particles that elicit an immune response against hemagglutinin (HA) proteins from a broad range of influenza viruses are provided. The nanoparticles are made from self-assembling proteins, at least one of which is joined to an immunogenic portion of an influenza HA protein. This immunogenic portion is displayed on the nanoparticle surface, making the nanoparticles useful for vaccinating subjects against influenza virus. |
| FILED | Friday, February 07, 2020 |
| APPL NO | 17/423565 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/145 (20130101) Original (OR) Class A61K 2039/55555 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/16 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072134 | Overstreet |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sonoran Biosciences, Inc. (Tempe, Arizona) |
| ASSIGNEE(S) | Sonoran Biosciences, Inc. (Tempe, Arizona) |
| INVENTOR(S) | Derek J. Overstreet (Tempe, Arizona) |
| ABSTRACT | A polymer composition can include an aqueous vehicle and a temperature-responsive degradable polymer having a polymer including a LCST-imparting unit and a lactone-bearing unit including a pendent lactone group. The number of LCST-imparting units is greater than the number of lactone-bearing units. The temperature-responsive degradable polymer has an initial lower critical solution temperature (LCST) of 37° C. or below. The polymer composition can have a pH lower than 7. |
| FILED | Tuesday, November 16, 2021 |
| APPL NO | 17/528111 |
| CURRENT CPC | Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 1/2096 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 31/435 (20130101) A61K 31/702 (20130101) A61K 31/7036 (20130101) A61K 47/32 (20130101) Original (OR) Class Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/19 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/58 (20130101) C08F 2800/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072148 | Wells et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | James Wells (San Francisco, California); Hai Tran (San Francisco, California); Susanna Elledge (Berkeley, California) |
| ABSTRACT | Provided herein are novel antibody-agent conjugates formed by the introduction of methionine residues to antibody scaffold light or heavy chains at select positions, followed by conjugation of the agent to the methionine, for example, by oxaziridine chemistries. Methionine substitutions at the targeted positions enable highly efficient functionalization to form very stable conjugates, including conjugates suitable for in vivo use. The positions were identified for the trastuzumab and other related scaffolds which can be engineered for affinity to any target antigen. The conjugates include ADCs and detections agents. Also disclosed are novel oxaziridine reagents for conjugation to methionines in proteins. |
| FILED | Monday, December 30, 2019 |
| APPL NO | 17/419246 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6851 (20170801) Original (OR) Class A61K 47/6855 (20170801) A61K 47/6889 (20170801) A61K 2039/505 (20130101) Heterocyclic Compounds C07D 413/06 (20130101) Peptides C07K 16/32 (20130101) C07K 16/464 (20130101) C07K 2317/92 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072153 | CHEN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Gong CHEN (Guangzhou, China PRC); Lei ZHANG (Sate College, Pennsylvania); Zheng WU (State College, Pennsylvania); Yuchen CHEN (State College, Pennsylvania); Fan WANG (State College, Pennsylvania); Ziyuan GUO (State College, Pennsylvania) |
| ABSTRACT | Methods for producing new neurons in the brain in vivo are provided according to aspects of the present invention which include introducing NeuroD1 into a glial cell, particularly into a reactive astrocyte or NG2 cell, thereby “converting” the reactive glial cell to a neuron. Methods of producing a neuronal phenotype in a glial cell are provided according to aspects of the present invention which include expressing exogenous NeuroD1 in the glial cell, wherein expressing exogenous NeuroD1 includes delivering an expression vector, such as a viral expression vector, including a nucleic acid encoding the exogenous NeuroD1 to the glial cell. |
| FILED | Friday, October 15, 2021 |
| APPL NO | 17/502944 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) A61K 48/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072156 | OLSON et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Eric N. OLSON (Dallas, Texas); Chengzu LONG (Dallas, Texas); John R. McANALLY (Dallas, Texas); John M. SHELTON (Dallas, Texas); Rhonda BASSEL-DUBY (Dallas, Texas) |
| ABSTRACT | Duchenne muscular dystrophy (DMD) is an inherited X-linked disease caused by mutations in the gene encoding dystrophin, a protein required for muscle fiber integrity. The disclosure reports CRISPR/Cas9-mediated gene editing (Myo-editing) is effective at correcting the dystrophin gene mutation in the mdx mice, a model for DMD. Further, the disclosure reports optimization of germline editing of mdx mice by engineering the permanent skipping of mutant exon (exon 23) and extending exon skipping to also correct the disease by post-natal delivery of adeno-associate virus (AAV). AAV-mediated Myo-editing can efficiently rescue the reading frame of dystrophin in mdx mice in vivo. The disclosure reports means of Myo-editing-mediated exon skipping has been successfully advanced from somatic tissues in mice to human DMD patients-derived iPSCs (induced pluripotent stem cells). Custom Myo-editing was performed on iPSCs from patients with differing mutations and successfully restored dystrophin protein expression for all mutations in iPSCs-derived cardiomyocytes. |
| FILED | Tuesday, August 17, 2021 |
| APPL NO | 17/404915 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/465 (20130101) A61K 48/0058 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/20 (20170501) C12N 2750/14143 (20130101) Enzymes C12Y 301/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072227 | Patel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Beta Bionics, Inc. (Irvine, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Himanshu Patel (Rancho Santa Margarita, California); Michael J. Rosinko (Las Vegas, Nevada); Edward R. Damiano (Acton, Massachusetts); David Chi-Wai Lim (Irvine, California); Firas H. El-Khatib (Allston, Massachusetts); John R. Costik (Livonia, New York); Justin P. Brown (Tustin, California); Bryan Dale Knodel (Flagstaff, Arizona) |
| ABSTRACT | Systems and methods are disclosed herein for switching an application executing on an ambulatory medical device to a new application without interrupting therapy provided by the ambulatory medical device to a subject. The ambulatory medical device may receive an indication that an update to an application executing on the ambulatory insulin pump is available, establish a communication connection to a host computing system, download and install the application update, while a prior version of the application continues to run. The disclosed systems and methods can confirm successful installation of the application update on the ambulatory medical device and switch control of the ambulatory medical device from the prior version to the new version of the application without interrupting therapy provided to the subject. |
| FILED | Friday, September 17, 2021 |
| APPL NO | 17/478071 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/142 (20130101) A61M 5/172 (20130101) Original (OR) Class A61M 5/1723 (20130101) A61M 5/14244 (20130101) A61M 5/14248 (20130101) A61M 5/16831 (20130101) A61M 2205/18 (20130101) A61M 2205/52 (20130101) A61M 2205/3553 (20130101) A61M 2230/201 (20130101) Electric Digital Data Processing G06F 3/04847 (20130101) G06F 3/04883 (20130101) G06F 8/61 (20130101) G06F 8/65 (20130101) G06F 8/656 (20180201) G06F 21/31 (20130101) G06F 21/84 (20130101) G06F 21/305 (20130101) G06F 21/6245 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/18 (20130101) G08B 21/0453 (20130101) G08B 25/00 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 20/17 (20180101) G16H 40/40 (20180101) G16H 40/60 (20180101) G16H 40/67 (20180101) G16H 50/30 (20180101) G16H 80/00 (20180101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/30 (20130101) H04L 9/088 (20130101) H04L 63/101 (20130101) H04L 67/34 (20130101) Wireless Communication Networks H04W 76/10 (20180201) H04W 76/14 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072228 | Rosinko et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Beta Bionics, Inc. (Irvine, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael J. Rosinko (Las Vegas, Nevada); Edward R. Damiano (Acton, Massachusetts); David Chi-Wai Lim (Irvine, California); Firas H. El-Khatib (Allston, Massachusetts); Himanshu Patel (Rancho Santa Margarita, California); John R. Costik (Livonia, New York); Justin P. Brown (Tustin, California); Bryan Dale Knodel (Flagstaff, Arizona) |
| ABSTRACT | Systems and methods are disclosed herein for switching control of an ambulatory medical device from an application executing on the ambulatory medical device to a safe version or a new version of the application without interrupting therapy provided by the ambulatory medical device to a subject. The ambulatory medical device can maintain copies of a safe version and a new version of the application. The disclosed systems and methods can execute the new version, while the prior version of the application continues to execute, determine whether a minimum set of operating conditions are satisfied by the new version, and switch control of the ambulatory medical device from the prior version to the new version. The systems and methods can also automatically revert to the safe version of the application case the current version is malfunctioning without interrupting therapy provided to the subject. |
| FILED | Friday, September 17, 2021 |
| APPL NO | 17/478146 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/142 (20130101) A61M 5/172 (20130101) Original (OR) Class A61M 5/1723 (20130101) A61M 5/14244 (20130101) A61M 5/14248 (20130101) A61M 5/16831 (20130101) A61M 2205/18 (20130101) A61M 2205/52 (20130101) A61M 2205/3553 (20130101) A61M 2230/201 (20130101) Electric Digital Data Processing G06F 3/04847 (20130101) G06F 3/04883 (20130101) G06F 8/61 (20130101) G06F 8/65 (20130101) G06F 8/656 (20180201) G06F 21/31 (20130101) G06F 21/84 (20130101) G06F 21/305 (20130101) G06F 21/6245 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/18 (20130101) G08B 21/0453 (20130101) G08B 25/00 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 20/17 (20180101) G16H 40/40 (20180101) G16H 40/60 (20180101) G16H 40/67 (20180101) G16H 50/30 (20180101) G16H 80/00 (20180101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/30 (20130101) H04L 9/088 (20130101) H04L 63/101 (20130101) H04L 67/34 (20130101) Wireless Communication Networks H04W 76/10 (20180201) H04W 76/14 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072533 | Davidowitz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BioTillion, LLC (Skillman, New Jersey) |
| ASSIGNEE(S) | BioTillion, LLC (Skillman, New Jersey) |
| INVENTOR(S) | Hananel Davidowitz (Princeton, New Jersey); Theodore N. Altman (East Windsor, New Jersey); Ke Wang (Flemington, New Jersey); Ron Or (Moshav Bney Atarot, Israel); Zhengyan Zhai (Doylestown, Pennsylvania); Jeremy Basch (Middlesex, New Jersey) |
| ABSTRACT | A storage system having racks and an outer container that receives the racks, each rack receiving a plurality of sample boxes, each box having a wireless ID tag. In certain embodiments, the storage system has reader electronics external to and distinct from the racks and that directly read the wireless ID tag of each box in at least one rack without relying on any reader electronics of any rack. In other embodiments, each rack has a set of rack reader electronics that read the wireless ID tag of each box in at least one rack, and the storage system has at least one removable reader access device removably connectable to the set of rack reader electronics of a rack in order to transmit the ID number of the wireless ID tag of each box in the rack outside of the outer container. |
| FILED | Thursday, October 14, 2021 |
| APPL NO | 17/501437 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 10/0096 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/545 (20130101) B01L 3/5085 (20130101) Original (OR) Class B01L 7/50 (20130101) B01L 2300/022 (20130101) B01L 2300/023 (20130101) Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors B65G 1/1371 (20130101) B65G 2203/046 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 35/00732 (20130101) G01N 2035/00445 (20130101) G01N 2035/00772 (20130101) G01N 2035/00801 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072542 | Ros et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alexandra Ros (Phoenix, Arizona); Daihyun Kim (Mesa, Arizona); Jinghui Luo (Covina, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexandra Ros (Phoenix, Arizona); Daihyun Kim (Mesa, Arizona); Jinghui Luo (Covina, California) |
| ABSTRACT | Sub-micrometer bioparticles are separated by size in a microfluidic channel utilizing a ratchet migration mechanism. A structure within the microfluidic channel includes an array of micro-posts arranged in laterally shifted rows. Reservoirs are disposed at each end of the microfluidic channel. A biased AC potential is applied across the channel via electrodes immersed into fluid in each of the reservoirs to induce a non-uniform electric field through the microfluidic channel. The applied potential comprises a first waveform with a first frequency that induces electro-kinetic flow of sub-micrometer bioparticles in the microfluidic channel, and an intermittent superimposed second waveform with a higher frequency. The second waveform selectively induces a dielectrophoretic trapping force to selectively impart ratchet migration based on particle size for separating the sub-micrometer bioparticles by size in the microfluidic channel. |
| FILED | Friday, November 12, 2021 |
| APPL NO | 17/524976 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502715 (20130101) Original (OR) Class B01L 3/502753 (20130101) B01L 3/502761 (20130101) B01L 2200/0647 (20130101) B01L 2200/0652 (20130101) B01L 2300/0816 (20130101) B01L 2400/0406 (20130101) B01L 2400/0424 (20130101) Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 5/005 (20130101) B03C 5/026 (20130101) B03C 5/028 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2001/4038 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072697 | Johnson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as Represented by the Secretary, Department of Health and Human Servic (Bethesda, Maryland); Thomas Jefferson University (Philadelphia, Pennsylvania); University of Maryland, Baltimore (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Reed F. Johnson (Frederick, Maryland); Matthias Schnell (Harleysville, Pennsylvania); Lisa E. Hensley (Frederick, Maryland); Christoph Wirblich (Philadelphia, Pennsylvania); Christopher M. Coleman (Owings Mills, Maryland); Matthew S. Frieman (Baltimore, Maryland) |
| ABSTRACT | The present disclosure provides methods and compositions for inducing an immune response that confers dual protection against infections by either or both of a rabies virus and a coronavirus, and/or which can be used therapeutically for an existing infection with rabies virus and/or a coronavirus to treat at least one symptom thereof and/or to neutralize or clear the infecting agents. In particular, the present disclosure provides a recombinant rabies virus vector comprising a nucleotide sequence encoding at least one coronavirus immunogenic glycoprotein fragment, as well as pharmaceutical compositions comprising the vaccine vectors. |
| FILED | Tuesday, May 04, 2021 |
| APPL NO | 17/307066 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/205 (20130101) A61K 39/215 (20130101) A61K 2039/5254 (20130101) Workshop Equipment, e.g for Marking-out Work; Storage Means for Workshops B25H 3/003 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072753 | McAlpine et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Menneapolis, Minnesota); U.S. Government as Represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael C. McAlpine (Minneapolis, Minnesota); Ruitao Su (Minneapolis, Minnesota); Steven J. Koester (Edina, Minnesota); Joshua Uzarski (Boston, Massachusetts) |
| ABSTRACT | A printed structure including a plurality of overlying layers of elongate polymeric filaments stacked on a surface of a substrate. The elongate polymeric filaments are stacked on each other along their lengths to form a liquid impermeable, self-supporting wall. The liquid impermeable self-supporting wall forms a wall angle of about 30° to about 90° with respect to a plane of the surface of the substrate. |
| FILED | Wednesday, November 18, 2020 |
| APPL NO | 16/951794 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 35/0805 (20130101) B29C 48/05 (20190201) Original (OR) Class B29C 48/30 (20190201) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Compositions of Macromolecular Compounds C08L 83/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073495 | Fontoura et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of The Universtiy of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of The Universtiy of Texas System (Austin, Texas) |
| INVENTOR(S) | Beatriz M.A. Fontoura (Dallas, Texas); Matthew A. Esparza (Dallas, Texas); Hanspeter Niederstrasser (Coppell, Texas); Bruce Posner (Richardson, Texas); Joseph M. Ready (Carrollton, Texas); Amir Mor (Nes-Ziona, Israel) |
| ABSTRACT | The present disclosure provides, in part, compositions, kits and methods for treating or preventing an influenza viral infection by administering a therapeutically effective amount of an inhibitor of influenza viral M mRNA nuclear export to a subject in need. |
| FILED | Tuesday, November 16, 2021 |
| APPL NO | 17/527907 |
| CURRENT CPC | Heterocyclic Compounds C07D 235/28 (20130101) C07D 401/12 (20130101) Original (OR) Class C07D 413/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073519 | El-Deiry et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Institute For Cancer Research d/b/a The Research Institute Of Fox Chase Cancer Center (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Wafik S. El-Deiry (Philadelphia, Pennsylvania); Shengliang Zhang (Philadelphia, Pennsylvania); Liz J. Hernandez Borrero (Philadelphia, Pennsylvania) |
| ABSTRACT | The disclosure generally relates to compounds, compositions, and methods for the treatment of cancer by restoring the P53 pathway signaling to repress cancer cell growth. |
| FILED | Tuesday, November 16, 2021 |
| APPL NO | 17/527536 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/522 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 473/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073577 | Guillemin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Oregon (Eugene, Oregon) |
| ASSIGNEE(S) | University of Oregon (Eugene, Oregon) |
| INVENTOR(S) | Karen Guillemin (Eugene, Oregon); Annah Rolig (Eugene, Oregon); Emily Sweeney (Eugene, Oregon) |
| ABSTRACT | Methods of treating or inhibiting inflammation in a subject include administering an anti-inflammatory protein to the subject. In some embodiments, the protein has at least 80% sequence identity to the amino acid sequence set forth as SEQ ID NO: 1, SEQ ID NO: 11, or fragments thereof. Isolated polypeptides, nucleic acids, and recombinant vectors including a nucleic acid encoding the anti-inflammatory protein (such as a nucleic acid encoding a protein with at least 80% sequence identity to SEQ ID NO: 1, SEQ ID NO: 11, or fragments thereof) operably linked to a heterologous promoter are also disclosed. |
| FILED | Tuesday, November 23, 2021 |
| APPL NO | 17/533320 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) Peptides C07K 4/12 (20130101) C07K 14/4702 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073597 | YOUNG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Travis S. YOUNG (La Jolla, California); Leonard PRESTA (La Jolla, California); David RODGERS (La Jolla, California); Eric HAMPTON (La Jolla, California); Timothy WRIGHT (La Jolla, California); Peter G. SCHULTZ (La Jolla, California); Eduardo LABORDA (La Jolla, California); Elvira KHIALEEVA (La Jolla, California); Sophie VIAUD (La Jolla, California) |
| ABSTRACT | The present disclosure provides compositions, methods, kits, and platforms for selectively activating and deactivating chimeric receptor effector cells using humanized chimeric receptor effector cell switches that comprise a humanized targeting moiety that binds CD19 on a target cell and a chimeric receptor interacting domain that binds to a chimeric receptor effector cell and/or chimeric receptor effector cell switches comprising optimized chimeric receptor interacting domains. Also disclosed are methods of treating disease and conditions with such chimeric receptor effector cells and chimeric receptor effector cell switches. |
| FILED | Monday, August 30, 2021 |
| APPL NO | 17/461365 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/507 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 14/70578 (20130101) C07K 16/18 (20130101) Original (OR) Class C07K 16/2803 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073611 | Dessain et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lankenau Institute for Medical Research (Wynnewood, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Scott K. Dessain (Wynnewood, Pennsylvania); Rashmi Sharma (King of Prussia, Pennsylvania); Fetweh H. AL-SALEEM (Philadelphia, Pennsylvania) |
| ABSTRACT | A recombinant, synthetic or monoclonal human antibody or fragment thereof that binds to an N-methyl-D-aspartate Receptor (NMDAR) epitope, which antibody or fragment comprises at least one a heavy chain variable domain sequence encoded by a nucleic acid sequence that is at least 80% identical to SEQ ID NOs. 1, 3, or 5; or at least one a light chain variable domain sequence encoded by a nucleic acid sequence that is at least 80% identical to SEQ ID NOs: 2, 4, or 6. Assays for diagnosis of ANRE employ these NMDAR-binding antibodies, constructs, or epitope binding fragments. In one embodiment, multiple of the NMDAR-binding antibodies or fragments are used as controls because they bind non-overlapping target sequences on the NMDAR ATD. |
| FILED | Saturday, June 08, 2019 |
| APPL NO | 17/599399 |
| CURRENT CPC | Peptides C07K 16/286 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) G01N 2333/70571 (20130101) G01N 2800/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073872 | Demirci et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Brigham and Women`s Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Utkan Demirci (Cambridge, Massachusetts); Xiaohui Zhang (Shaanxi, China PRC); Emre Kayaalp (Tenafly, New Jersey); Hooman Safaee (Mississauga, Canada); Savas Tasoglu (Cambridge, Massachusetts); Paolo Nicolas Catalano (Ciudad de Buenos Aires, Argentina) |
| ABSTRACT | A method for sorting motile cells includes introducing an initial population of motile cells into an inlet port of a microfluidic channel, the initial population of motile cells having a first average motility; incubating the population of motile cells in the microfluidic channel; and collecting a sorted population of motile cells at an outlet port of the microfluidic channel. The sorted population of motile cells has a second average motility higher than the first average motility. |
| FILED | Friday, August 20, 2021 |
| APPL NO | 17/407609 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502746 (20130101) B01L 3/502761 (20130101) B01L 2200/0652 (20130101) B01L 2200/0694 (20130101) B01L 2300/0654 (20130101) B01L 2300/0816 (20130101) B01L 2300/0858 (20130101) B01L 2300/0887 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) C12M 33/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0612 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1484 (20130101) G01N 33/689 (20130101) G01N 33/5029 (20130101) G01N 33/6893 (20130101) G01N 2015/149 (20130101) G01N 2800/367 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073874 | Ichida et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Justin Ichida (Los Angeles, California); Kimberley N. Babos (Los Angeles, California); Kate E. Galloway (Los Angeles, California) |
| ABSTRACT | The disclosure relates methods for increasing the efficiency of cellular reprogramming of somatic cells and improving the maturity of the resulting cells. |
| FILED | Friday, September 10, 2021 |
| APPL NO | 17/472424 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) Original (OR) Class C12N 5/0696 (20130101) C12N 2501/15 (20130101) C12N 2501/20 (20130101) C12N 2501/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073879 | YEE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| ASSIGNEE(S) | The Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| INVENTOR(S) | Cassian YEE (Houston, Texas); Yongqing LI (Kent, Washington) |
| ABSTRACT | A method of carrying out adoptive immunotherapy by administering a subject an antigen-specific cytotoxic T lymphocytes (CTL) preparation in a treatment-effective amount is described. In the method, the CTL preparation is preferably administered as a preparation of an in vitro antigen-stimulated and expanded primate CTL population, the CTL population: (i) depleted of FoxP3+T lymphocytes prior to antigen stimulation; (ii) antigen-stimulated in vitro in the presence of interleukin-21; or (iii) both depleted of FoxP3+T lymphocytes prior to antigen stimulation and then antigen-stimulated in vitro in the presence of interleukin-21. Methods of preparing such compositions, and compositions useful for carrying out the adoptive immunotherapy, are also described. |
| FILED | Wednesday, August 11, 2021 |
| APPL NO | 17/400038 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/41 (20130101) A61K 35/12 (20130101) A61K 35/17 (20130101) A61K 39/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 5/0638 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073883 | Andersen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Peter Andersen (Baltimore, Maryland); Chulan Kwon (Ellicott City, Maryland) |
| ABSTRACT | The present invention relates to compositions and methods for producing, identifying and isolating heart progenitor cells. |
| FILED | Thursday, July 25, 2019 |
| APPL NO | 17/263142 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) A61K 35/34 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0657 (20130101) Original (OR) Class C12N 5/0696 (20130101) C12N 2501/15 (20130101) C12N 2501/16 (20130101) C12N 2501/21 (20130101) C12N 2501/155 (20130101) C12N 2501/415 (20130101) C12N 2506/45 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073891 | Abudayyeh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Omar Abudayyeh (Cambridge, Massachusetts); Jonathan Gootenberg (Cambridge, Massachusetts) |
| ABSTRACT | This disclosure provides systems, methods, and compositions for RNA-guided RNA-targeting CRISPR effectors for the treatment of diseases as well as diagnostics. In some embodiments, nucleotide deaminase functionalized CRISPR systems for RNA editing RNA knockdown, viral resistance, splicing modulation, RNA tracking, translation modulation, and epi-transcriptomic modifications are disclosed. |
| FILED | Thursday, July 01, 2021 |
| APPL NO | 17/365777 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 9/78 (20130101) C12N 15/11 (20130101) C12N 2310/20 (20170501) C12N 2320/33 (20130101) Enzymes C12Y 305/04004 (20130101) C12Y 305/04005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073894 | Stafford et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Darrel W. Stafford (Carrboro, North Carolina); Dengmin Feng (Guangzhou, China PRC) |
| ABSTRACT | Factor IX proteins are described with an increase in the number of glycosylation sites and other modifications to provide Factor IX proteins that have higher specific activity and a longer useful clotting function relative to wild type or non-modified Factor IX protein. |
| FILED | Friday, April 16, 2021 |
| APPL NO | 17/232942 |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 2217/00 (20130101) A01K 2227/105 (20130101) A01K 2267/01 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/4846 (20130101) Peptides C07K 14/745 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/644 (20130101) Original (OR) Class C12N 15/87 (20130101) Enzymes C12Y 304/21022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073899 | RAINES et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ronald T. RAINES (Madison, Wisconsin); Kalie MIX (Madison, Wisconsin) |
| ABSTRACT | Methods and reagents for esterification of biological molecules including proteins, polypeptides and peptides. Diazo compounds of formula I: where R is hydrogen, an alkyl, an alkenyl or an alkynyl, RA represents 1-5 substituents on the indicated phenyl ring and RM is an organic group. RM includes a label, a cell penetrating group, a cell targeting group, or a reactive group or latent reactive group for reaction to bond to a label, a cell penetrating group, or a cell targeting group, among other organic groups useful for esterification of biological molecules. Also provided are diazo compounds which are bifunctional and trifunctional coupling reagents as well as reagents for the synthesis of compounds of formula I. |
| FILED | Monday, November 15, 2021 |
| APPL NO | 17/526816 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 231/12 (20130101) C07C 245/18 (20130101) C07C 269/06 (20130101) C07C 319/12 (20130101) Heterocyclic Compounds C07D 207/46 (20130101) Peptides C07K 1/13 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/96 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073903 | Halvorsen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for the State University of New York (Albany, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kenneth Halvorsen (Glenmont, New York); Lifeng Zhou (Albany, New York) |
| ABSTRACT | The present disclosure is directed to ribonucleic acid (RNA) isolation and purification. For example, the present disclosure relates to a method of purifying a single ribonucleic acid (RNA) species, including: isolating a DNA nanoswitch-target complex within a gel medium, wherein the DNA nanoswitch-target complex includes a DNA nanoswitch and a target-of-interest; digesting the DNA nanoswitch and the gel medium to form digested byproducts, and a free target-of-interest; and isolating the free target-of-interest, wherein the free target-of-interest is a single RNA species. |
| FILED | Tuesday, July 06, 2021 |
| APPL NO | 17/368718 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1024 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073910 | Disney |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew D. Disney (Jupiter, Florida) |
| ABSTRACT | Disclosed herein are compounds and methods to identify the direct RNA targets of small molecules in cells is described. The approach, dubbed Chemical Cross-Linking and Isolation by Pull-down to Map Small Molecule-RNA Binding Sites (Chem-CLIP-Map-Seq), appends a cross-linker and a purification tag onto a small molecule. In cells, the compound binds to RNA and undergoes a proximity-based reaction. The cross-linked RNA is purified and then amplified using a universal reverse transcription (RT) primer and gene-specific PCR primers. At nucleotides proximal to the binding site, RT “stops” are observed. This approach has broad utility in identifying and validating the RNA targets and binding sites of small molecules in the context of a complex cellular system. |
| FILED | Tuesday, February 11, 2020 |
| APPL NO | 17/419654 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1096 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6851 (20130101) C12Q 1/6886 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073918 | COREY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of The University of Texas System (Austin, Texas) |
| INVENTOR(S) | David COREY (Dallas, Texas); Jiaxin HU (Coppell, Texas) |
| ABSTRACT | Provided herein are compositions and methods for reducing expression of C9orf72 transcripts in cells containing expanded intronic GGGGCC regions, including those in subjects having or at risk of developing amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). |
| FILED | Wednesday, November 17, 2021 |
| APPL NO | 17/528383 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/3231 (20130101) C12N 2310/3521 (20130101) C12N 2320/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073963 | Hamad et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Abdel Rahim Hamad (Ellicott City, Maryland); Thomas Donner (Baltimore, Maryland); Rizwan Ahmed (Baltimore, Maryland); Zahra Omidian (Baltimore, Maryland) |
| ABSTRACT | The present invention relates to the field of diabetes. More specifically, the present invention provides compositions and methods useful for diagnosing and treating Type I diabetes. In one embodiment, a method comprises detecting a nucleotide sequence encoding SEQ ID NO:1 from a biological sample obtained from a patient. In another embodiment, the present invention provides an antibody or antigen-binding fragment thereof that specifically binds SEQ ID NO:1. In a further embodiment, the present invention provides an antibody or antigen-binding fragment thereof that specifically binds (i) a B-cell receptor expressed on a lymphocyte, wherein the B-cell receptor comprises SEQ ID NO:1; or (ii) a free-floating antibody comprising SEQ ID NO:1. |
| FILED | Friday, December 20, 2019 |
| APPL NO | 17/416778 |
| CURRENT CPC | Peptides C07K 16/28 (20130101) C07K 16/42 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class C12Q 1/6881 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073977 | Papadopoulos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nickolas Papadopoulos (Towson, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Bert Vogelstein (Baltimore, Maryland); Joshua David Cohen (Baltimore, Maryland) |
| ABSTRACT | Provided herein are systems, kits, compositions and methods for sequencing library preparation and sequencing workflow (e.g., for the identification of mutations). In certain embodiments, provides herein systems and methods to identically barcode both strands of templates, and PCR-based enrichment of each strand that does not require hybridization capture. |
| FILED | Friday, February 12, 2021 |
| APPL NO | 17/174838 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6855 (20130101) Original (OR) Class C12Q 1/6876 (20130101) C12Q 2563/185 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073998 | Oliver et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Trudy Oliver (Salt Lake City, Utah); Martin Sos (Salt Lake City, Utah); Rob Wechsler-Reya (Salt Lake City, Utah) |
| ABSTRACT | Described herein are methods and compositions useful in detecting, diagnosing and treating small cell lung cancer. Transgenic animal models and cell lines are disclosed for the study of a small cell lung cancer subtype. Methods of screening and identifying active agents for the treatment of a small cell lung cancer subtype as well as methods of identifying patients susceptible to treatment with aurora kinase inhibitors are also provided. |
| FILED | Monday, September 20, 2021 |
| APPL NO | 17/479701 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073999 | He |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Kansas (Lawrence, Kansas); Kansas State University Research Foundation (Manhattan, Kansas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mei He (Gainesville, Florida) |
| ABSTRACT | Methods for producing engineered exosomes and other vesicle-like biological targets, including allowing a target vesicle-like structure to react and bind with immunomagnetic particles; capturing the immunomagnetic particle/vesicle complex by applying a magnetic field; further engineering the captured vesicles by surface modifying with additional active moieties or internally loading with active agents; and releasing the engineered vesicle-like structures, such as by photolytically cleaving a linkage between the particle and engineered vesicle-like structures, thereby releasing intact vesicle-like structures which can act as delivery vehicles for therapeutic treatments. |
| FILED | Friday, October 29, 2021 |
| APPL NO | 17/514724 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6901 (20170801) A61K 49/0097 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 3/502761 (20130101) Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 1/015 (20130101) B03C 1/30 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/5434 (20130101) G01N 33/54333 (20130101) G01N 2446/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220074001 | Vinje et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Servic (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jan Vinje (Decatur, Georgia); Nicole Gregoricus (Atlanta, Georgia); Preeti Chhabra (Atlanta, Georgia); Leslie Barclay (Atlanta, Georgia) |
| ABSTRACT | A process for detecting norovirus nucleic acid in a sample is provided including producing an amplification product by amplifying a norovirus nucleotide sequence using a forward primer of SEQ ID NO: 1, 4, or 10 and a reverse primer of SEQ ID NO: 2, 5, or 11, and detecting the amplification product to detect norovirus in the sample. Also provided are reagents and methods for detecting and distinguishing GI or Gil norovirus from other infectious agents. A kit is provided for detecting and quantifying norovirus in a sample. |
| FILED | Tuesday, November 23, 2021 |
| APPL NO | 17/456323 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/701 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220074505 | Harbrecht et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Tosoh Bioscience Wisconsin, Inc. (Madison, Wisconsin) |
| ASSIGNEE(S) | Tosoh Bioscience Wisconsin, Inc. (Madison, Wisconsin) |
| INVENTOR(S) | Brian A. Harbrecht (Janesville, Wisconsin); Robert Charles Mierendorf (Verona, Wisconsin); Scott G. Manke (Sun Prairie, Wisconsin) |
| ABSTRACT | An illustrative valve block includes a plate, a fluid transfer block, and a diaphragm. The plate includes a channel configured to receive a first fluid and a recess connected to the channel. The fluid transfer block includes an inlet connection configured to receive a second fluid and an outlet connection. The fluid transfer block also includes a plurality of valve inlet bores connected to the inlet connection. The plurality of valve inlet bores are distributed along at least part of a first curved shape. The fluid transfer block further includes a plurality of valve outlet bores each fluidly connected to the outlet connection. The plurality of valve outlet bores are distributed along at least part of a second curved shape. The diaphragm is between the pressure plate and the fluid transfer block. The plurality of valve inlet bores and the plurality of valve outlet bores adjoin the recess. |
| FILED | Monday, November 15, 2021 |
| APPL NO | 17/526465 |
| CURRENT CPC | Separation B01D 15/22 (20130101) B01D 15/1842 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 7/17 (20130101) Original (OR) Class F16K 11/22 (20130101) F16K 25/005 (20130101) F16K 27/003 (20130101) F16K 27/0236 (20130101) F16K 27/0263 (20130101) F16K 31/1266 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220074829 | Suzuki et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aussie Suzuki (Madison, Wisconsin); Mark E. Burkard (Cross Plains, Wisconsin); Roshan X. Norman (Madison, Wisconsin); Emma Recchia (Madison, Wisconsin) |
| ABSTRACT | Conventional expanded microscopy (ExM) is improved upon to show reliable and reproducible 4-fold and 12-fold modified expansion microscopy (mExM). Kits and methods are disclosed to achieve these improvements. The kits can include a sealable mold and instructions for using it in the improved methods. The kits can include a protein digestion buffer including sodium dodecyl sulfate and instructions for using the buffer in the improved methods. The improved methods can include a simplified approach to executing oxygen-sensitive reactions within the methods. The improved methods can include improved protein digestion chemistries, which can facilitate the improvements in reliability and reproducibility. |
| FILED | Friday, September 03, 2021 |
| APPL NO | 17/466434 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) G01N 1/36 (20130101) Original (OR) Class G01N 2001/366 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220074941 | Chiosis |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sloan-Kettering Institute for Cancer Research (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gabriela Chiosis (New York, New York) |
| ABSTRACT | This invention concerns a method for selecting an inhibitor of a cancer-implicated pathway or of a component of a cancer-implicated pathway for coadministration, with an inhibitor of HSP90, to a subject suffering from a cancer which comprises the following steps: (a) contacting a sample containing cancer cells from a subject with an inhibitor of HSP90 or an analog, homolog or derivative of an inhibitor of HSP90 under conditions such that one or more cancer pathway components present in the sample bind to the HSP90 inhibitor or the analog, homolog or derivative of the HSP90 inhibitor; (b) detecting pathway components bound to the HSP90 inhibitor or to the analog, homolog or derivative of the HSP90 inhibitor; (c) analyzing the pathway components detected in step (b) so as to identify a pathway which includes the components detected in step (b) and additional components of such pathway; and (d) selecting an inhibitor of the pathway or of a pathway component identified in step (c). This invention further concerns a methods of treating a cancer patient by coadministering an inhibitor of HSP90 and an inhibitor of a cancer-implicated pathway or component thereof. |
| FILED | Friday, August 28, 2020 |
| APPL NO | 17/006359 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/52 (20130101) A61K 45/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/5041 (20130101) G01N 33/5748 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220074942 | Pannell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of South Alabama (Mobile, Alabama) |
| ASSIGNEE(S) | University of South Alabama (Mobile, Alabama) |
| INVENTOR(S) | Lewis Kenneth Pannell (Dutton, Alabama); Michael Albert Finan (Theodore, Alabama); Rodney Paul Rocconi (Theodore, Alabama) |
| ABSTRACT | Useful, accessible, and predictive biomarkers for discriminating between ovarian cancer and benign adnexal masses are provided. Specifically, peptide biomarkers present in bodily fluid samples such as cervical-vaginal fluid (CVF) have been identified as having particularly robust diagnostic for identifying whether ovarian masses such as adnexal masses are benign, and ruling our ovarian cancer. The biomarker peptides disclosed herein therefore provide significantly enhanced sensitivity and specificity levels relative to extant methods for distinguishing benign ovarian masses from ovarian cancers. The biomarkers provide a timely and cost-efficient diagnostic capable of being used in a selection process to identify patients for whom treatment, which may include surgical resection and/or monitoring, may be performed by an obstetric gynecologist rather than a gynecologic oncologist. |
| FILED | Friday, August 20, 2021 |
| APPL NO | 17/407943 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57449 (20130101) Original (OR) Class G01N 2333/52 (20130101) G01N 2333/75 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220074944 | Srivastava et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as Represented by the Secretary,Department of Health and Human Service (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary,Department of Health and Human Service (Bethesda, Maryland) |
| INVENTOR(S) | Apurva Kumar Srivastava (Frederick, Maryland); Dominic Esposito (Middletown, Maryland); Jeevan Prasaad Govindharajulu (Frederick, Maryland); Ralph Ewin Parchment (Frederick, Maryland); James Halpern Doroshow (Bethesda, Maryland) |
| ABSTRACT | Immunoassays to detect the presence of Bcl-2 family heterodimeric complexes are described. The immunoassays are designed to detect one or more of BIM-Bcl-2, BIM-Bcl-xL, BIM-Mcl-1 and BAX-BAK heterodimers. The assays can be used, for example, to select a BH3 mimetic, or other drug targeting the apoptosis pathway, that is effective for treating a specific cancer, or to select a subject who is likely to respond to a particular BH3 mimetic. |
| FILED | Wednesday, January 29, 2020 |
| APPL NO | 17/422972 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54313 (20130101) G01N 33/57492 (20130101) Original (OR) Class G01N 2333/705 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220075014 | Arias et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ana Claudia Arias (Lafayette, California); Karthik Gopalan (Berkeley, California); Alla Mykhaylivna Zamarayeva (Berkeley, California); Michael Zhi-Hon Liu (Duluth, Georgia); Shimon Michael Lustig (Moraga, California) |
| ABSTRACT | Methods for forming conformal magnetic resonance imaging (MRI) receive coil devices having at least one receive coil with at least one capacitor are provided and include providing a 3-dimensional (3D) mold structure matching a curvilinear shape of interest, and forming a receive coil pattern on an outer surface of the 3D mold structure. The forming of the receive coil pattern may include spraying and/or depositing a conductive material and a dielectric material on the outer surface of the mold structure to form the receive coil pattern. The forming a receive coil pattern may include forming the receive coil pattern on an outer surface of a flat substrate sheet, and vacuum forming an inner surface of the flat substrate sheet to the outer surface of the mold structure to form a shape-conforming substrate sheet. The shape-conforming substrate sheet may be removed from the mold and used in MRI studies. |
| FILED | Friday, November 19, 2021 |
| APPL NO | 17/530863 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/34007 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220076779 | Feinberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew P. Feinberg (Baltimore, Maryland); John Goutsias (Baltimore, Maryland); William G. Jenkinson (Baltimore, Maryland); Elisabet Pujadas (Baltimore, Maryland) |
| ABSTRACT | The present disclosure provides computational methods for epigenetic analysis as well as systems for implementing such analyses. |
| FILED | Friday, June 16, 2017 |
| APPL NO | 16/310176 |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) Original (OR) Class G16B 20/20 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220076787 | Ellington et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew Ellington (Austin, Texas); Austin Cole (Austin, Texas); Raghav Shroff (Austin, Texas); Ross Thyer (Austin, Texas) |
| ABSTRACT | A computer-implemented method of training a neural network to improve a characteristic of a protein comprises collecting a set of amino acid sequences from a database, compiling each amino acid sequence into a three-dimensional crystallographic structure of a folded protein, training a neural network with a subset of the three-dimensional crystallographic structures, identifying, with the neural network, a candidate residue to mutate in a target protein, and identifying, with the neural network, a predicted amino acid residue to substitute for the candidate residue, to produce a mutated protein, wherein the mutated protein demonstrates an improvement in a characteristic over the target protein. A system for improving a characteristic of a protein is also described. Improved blue fluorescent proteins generated using the system are also described. |
| FILED | Wednesday, October 27, 2021 |
| APPL NO | 17/512116 |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) G16B 30/00 (20190201) Original (OR) Class G16B 40/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220076799 | Engelhardt |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dalit Engelhardt (Cambridge, Massachusetts) |
| ABSTRACT | Techniques for determining a dosage plan for administering at least one therapeutic agent to a subject. The techniques include using at least one computer hardware processor to perform: accessing information specifying a plurality of cell population concentrations for a respective plurality of cell populations in a biological sample from a subject; and determining the dosage plan using a trained statistical model and the plurality of cell population concentrations, the dosage plan including one or more concentrations of the at least one therapeutic agent to be administered to the subject at one or more respective different times. The trained statistical model may be trained using an actor-critic reinforcement learning technique and a model of cell evolution. The trained statistical model may include a deep neural network. |
| FILED | Tuesday, January 07, 2020 |
| APPL NO | 17/420814 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/0454 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/13 (20180101) Original (OR) Class G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220078564 | Shen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Indiana University (Bloomington, Indiana) |
| ASSIGNEE(S) | The Trustees of Indiana University (Bloomington, Indiana) |
| INVENTOR(S) | Yi Shen (Bloomington, Indiana) |
| ABSTRACT | Disclosed is a system and method for individualized hearing aid prescription which consists of a test procedure that enables the fitting of an individualized estimation of the SII model to individual listeners efficiently and an optimization process which translates the resulting individualized model to the prescribed gains across frequencies for programming into the user's hearing aids. The test involves the recognition of one or more words presented in background noise, which better approximates the daily listening experiences of hearing-aid users compared to the pure-tone detection in a silent environment task which is commonly utilized during conventional audiometric testing. In the estimated SII model, five parameters describe in a custom fashion the relative weights of speech information across the five frequency bands for a given listener. The results from the speech test is used to determine the desirable amount of gain for each frequency region to optimize the user's aided speech intelligibility. The resulting gains for the individual may then be programmatically applied to the individual's prescribed hearing aid device(s). |
| FILED | Thursday, January 09, 2020 |
| APPL NO | 17/309945 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/123 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 25/43 (20130101) H04R 25/70 (20130101) Original (OR) Class H04R 25/505 (20130101) H04R 2225/43 (20130101) H04R 2430/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20220071529 | ADALIAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dvin ADALIAN (PASADENA, California); Samson CHEN (PASADENA, California); Muhammad M. JILANI (PASADENA, California); Axel SCHERER (PASADENA, California); Xiomara Linnette MADERO (PASADENA, California); Richard SMITH (PASADENA, California) |
| ABSTRACT | Measurement of target analytes is carried out with an enzyme-based sensor. The enzyme hydrogel is protected by a porous layer of a metallic material. The size of the pores is small enough to prevent degradation of the enzyme layer caused by the immune system of an organism, but large enough to allow transfer of molecules that participate in the electrochemical reaction allowing the enzyme to detect the target analytes. |
| FILED | Wednesday, August 18, 2021 |
| APPL NO | 17/405943 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1473 (20130101) A61B 5/14532 (20130101) A61B 5/14546 (20130101) A61B 5/14865 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220071928 | PHANSTIEL, IV et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida); TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Otto PHANSTIEL, IV (Orlando, Florida); John CONNOR (Boston, Massachusetts) |
| ABSTRACT | Disclosed herein are polyamine transport inhibitors (PTI) and methods of use as antivirals. Disclosed PTI compounds are useful as treatments for viral infections or can be used as prophylactic agents that protect high risk individuals from becoming infected by the virus. The disclosed PTI compounds can be used alone or in combination with other agents (or other antivirals) to improve patient outcomes such as DFMO (or Remdesivir). |
| FILED | Wednesday, September 08, 2021 |
| APPL NO | 17/469827 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/13 (20130101) A61K 31/16 (20130101) A61K 31/132 (20130101) Original (OR) Class A61K 31/155 (20130101) A61K 31/198 (20130101) A61K 31/404 (20130101) A61K 31/505 (20130101) A61K 31/513 (20130101) A61K 31/522 (20130101) A61K 31/675 (20130101) A61K 31/4706 (20130101) A61K 31/4985 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/12 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072350 | BAUSCH et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF HAWAII (Honolulu, Hawaii) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Douglas BAUSCH (Makawao, Hawaii); David ASKOV (Seattle, Washington) |
| ABSTRACT | Systems and methods are described for the global, rapid, and automatic detection of wildfire activity. Such systems and methods may also classify wildfires based on a new severity classification scheme. Wildfire activity may be tracked as wildfires migrate, grow, and combine. Additionally, because satellite systems currently collect over 4 million fire observations per year, a filtering mechanism is introduced to remove benign anthropogenic fires. To classify wildfire severity for generating alerts, the present disclosure also provides a logarithmic severity classification system based on 24-hour cumulative Fire Radiative Power (FRP). |
| FILED | Wednesday, December 18, 2019 |
| APPL NO | 17/312621 |
| CURRENT CPC | Fire-fighting A62C 3/0271 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072432 | Krikorian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Haig Francis Krikorian (Fullerton, California); Leo Ho Chi Hui (Alhambra, California) |
| ABSTRACT | In one example aspect, a computer-implemented for managing containment behavior of a member during an encounter in a competitive environment includes: receiving, by a computing device, input data relating to the encounter within the competitive environment; determining, by the computing device, a reachable opponent set identifying one or more opponents reachable by the member; determining, by the computing device, containment boundaries for the member based on attributes of the member; determining, by the computing device, one or more containment options based on the containment boundaries and the reachable opponent set; generating, by the computing device, a containment instruction based on a particular one of the one or more containment options; and outputting, by the computing device, the containment instruction to cause the member to move to a position identified in the particular one of the one or more containment options. |
| FILED | Friday, June 18, 2021 |
| APPL NO | 17/352116 |
| CURRENT CPC | Card, Board, or Roulette Games; Indoor Games Using Small Moving Playing Bodies; Video Games; Games Not Otherwise Provided for A63F 13/798 (20140902) Original (OR) Class Electric Digital Data Processing G06F 16/24578 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072576 | Albrecht |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | John William Albrecht (Silverdale, Washington) |
| ABSTRACT | Apparatuses and methods related to improving environmental protection and waste collection from application of deposition material using portable systems that are easier for operators to use on surfaces such as ship hulls are provided. Embodiments include a portable and repositionable deposition material applicator enclosure and application system for applying deposition material on a substrate employing non-adherent deposition material waste removal and selective enclosure coupling and decoupling structures or systems employing magnetic and suction or differential pressure based forces. |
| FILED | Monday, November 15, 2021 |
| APPL NO | 17/526106 |
| CURRENT CPC | Spraying Apparatus; Atomising Apparatus; Nozzles B05B 14/30 (20180201) Original (OR) Class Apparatus for Applying Fluent Materials to Surfaces, in General B05C 11/1039 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/06 (20130101) B05D 1/12 (20130101) B05D 2401/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072685 | Reimers |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PCCI, Inc. (Alexandria, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen Reimers (Falls Church, Virginia) |
| ABSTRACT | The present invention is generally directed towards clamps for high tension load applications. In particular, the invention relates to high holding power clamps in which fabric can be secured, and which can withstand a large amount of force, including, in at least some embodiments, the maximum amount of tension permitted in various modern high strength fabrics and/or fiber weaves. In at least one embodiment, a holding clamp has a single-V design, with at least three areas that exert pinching effects on fabric held in the clamp, and at least four capstan areas that exert capstan effects on the clamped fabric. In at least a further embodiment, a holding clamp has a double-V design, with at least six areas that exert pinching effects on fabric held in the clamp, and at least seven capstan areas that exert capstan effects on the clamped fabric. |
| FILED | Friday, September 03, 2021 |
| APPL NO | 17/466853 |
| CURRENT CPC | Tools or Bench Devices Not Otherwise Provided For, for Fastening, Connecting, Disengaging or Holding B25B 5/02 (20130101) B25B 5/14 (20130101) B25B 5/163 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072700 | Cardenas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Boston Engineering Corporation (Waltham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert Lee Cardenas (Framingham, Massachusetts); Michael Conry (Beverly, Massachusetts); Todd Scrimgeour (Brighton, Massachusetts); Willard Ober (Atlanta, Georgia); Michael Rufo (Hanover, Massachusetts) |
| ABSTRACT | A robotic system which includes a fluid controller, an arm portion, and a soft end effector apparatus coupled with the fluid controller and the arm portion. The soft end effector apparatus includes a base constructed and arranged to mount to the arm portion, a set of wrist assemblies coupled with the base, and a set of finger assemblies coupled with the set of wrist assemblies. Each wrist assembly of the set of wrist assemblies (i) couples with a respective finger assembly and (ii) provides movement to that respective finger assembly relative to the base during actuation of that wrist assembly and during independent actuation of that respective finger assembly in response to control from the fluid controller. Along these lines, the fluid controller may individually provide pressurized fluid to each wrist assembly and each finger assembly when controlling interaction between the soft end effector apparatus and an external object. |
| FILED | Thursday, April 22, 2021 |
| APPL NO | 17/237212 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/142 (20130101) Original (OR) Class B25J 15/10 (20130101) B25J 15/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072743 | Ren et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for the State University of New York (Albany, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shenqiang Ren (Williamsville, New York); Lu aN (Buffalo, New York) |
| ABSTRACT | Systems for forming thermoplastic components are disclosed. A system may include a mold including a first portion and a second portion engaging the first portion. The first portion and/or the second portion may receive material for the component. The system may also include a compressive device positioned adjacent to and contacting the first portion of the mold. Additionally, the system may include a control system in communication with the compressive device. The control system may be configured to displace the compressive device to apply a compressive force to the first portion of the mold, and impose a predetermined pressure on the material for the component. The control system may also be configured to heat the first portion and/or the second portion of the mold. |
| FILED | Monday, June 28, 2021 |
| APPL NO | 17/360660 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 43/52 (20130101) Original (OR) Class B29C 43/58 (20130101) B29C 66/7212 (20130101) B29C 70/44 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2101/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072753 | McAlpine et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Menneapolis, Minnesota); U.S. Government as Represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael C. McAlpine (Minneapolis, Minnesota); Ruitao Su (Minneapolis, Minnesota); Steven J. Koester (Edina, Minnesota); Joshua Uzarski (Boston, Massachusetts) |
| ABSTRACT | A printed structure including a plurality of overlying layers of elongate polymeric filaments stacked on a surface of a substrate. The elongate polymeric filaments are stacked on each other along their lengths to form a liquid impermeable, self-supporting wall. The liquid impermeable self-supporting wall forms a wall angle of about 30° to about 90° with respect to a plane of the surface of the substrate. |
| FILED | Wednesday, November 18, 2020 |
| APPL NO | 16/951794 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 35/0805 (20130101) B29C 48/05 (20190201) Original (OR) Class B29C 48/30 (20190201) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Compositions of Macromolecular Compounds C08L 83/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073394 | Medina et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as Represented by The Secretary of The Army (Alexandria, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Victor F Medina (Clinton, Mississippi); Scott A Waisner (Vicksburg, Mississippi); Charles C Ellison (Vicksburg, Mississippi); Jose Mattei-Sosa (Vicksburg, Mississippi); Jacob M Lalley (Vicksburg, Mississippi); Christopher S Griggs (Vicksburg, Mississippi) |
| ABSTRACT | In one embodiment, a system of PFAS (Per-Poly-fluorinated alkyl substances) effluent liquid treatment includes: a pump to pump a liquid received via an intake; a sediment filter to filter sediment from the liquid; a granular activated carbon (GAC) device, disposed downstream of the sediment filter, to remove organic contaminants from the liquid; one (preferably two) or more ion exchange resin columns, disposed downstream of the GAC device, to remove PFAS constituents from the liquid; and a plurality of control valves being controlled to direct the liquid to flow along one or more liquid flow paths through the ion exchange resin columns so as to adjust a rate of processing the liquid by the one or more ion exchange resin columns. The system is disposed in a shipping container to be transported to a destination and is set up in the container onsite at the destination. |
| FILED | Friday, June 25, 2021 |
| APPL NO | 17/359384 |
| CURRENT CPC | Separation B01D 15/125 (20130101) B01D 15/163 (20130101) B01D 15/361 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 47/02 (20130101) B01J 47/14 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 9/00 (20130101) Original (OR) Class C02F 2103/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073502 | Piercey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Davin Glenn Piercey (Lafayette, Indiana); Matthew Lee Gettings (West Lafayette, Indiana) |
| ABSTRACT | The present disclosure relates to a novel tetrazole azasydnone, a method of making the novel tetrazole azasydnone, and a method of using the novel tetrazole azasydnone as a primary explosive. In one aspect, the novel tetrazole azasydnone has a structure of formula I: wherein A⊕ represents a cation with a 1+ charge. |
| FILED | Monday, June 07, 2021 |
| APPL NO | 17/340151 |
| CURRENT CPC | Heterocyclic Compounds C07D 413/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073565 | LANGAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert LANGAN (Seattle, Washington); Andrew NG (Oakland, California); Scott BOYKEN (Seattle, Washington); Marc LAJOIE (Seattle, Washington); Hana EL-SAMAD (Oakland, California); David BAKER (Seattle, Washington) |
| ABSTRACT | Disclosed herein are non-naturally occurring cage polypeptides, kits and degron LOCKRs including the cage polypep-tides, and uses thereof, wherein the cage polypeptides include (a) a helical bundle, comprising between 2 and 7 alpha-helices, wherein the helical bundle includes: (i) a structural region; and (ii) a latch region, wherein the latch region composes a degron located within the latch region, wherein the structural region interacts with the latch region to prevent activity of the degron; and (b) amino acid linkers connecting each alpha helix |
| FILED | Monday, January 06, 2020 |
| APPL NO | 17/419413 |
| CURRENT CPC | Peptides C07K 14/001 (20130101) Original (OR) Class C07K 2319/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073866 | Stelinski |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kirsten Stelinski (Winter Haven, Florida) |
| ABSTRACT | The present disclosure is directed to materials and method for genetically modifying Wolbachia, as well as arthropods comprising the modified Wolbachia. |
| FILED | Wednesday, November 13, 2019 |
| APPL NO | 17/293608 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/205 (20210501) Original (OR) Class C12N 9/22 (20130101) C12N 15/74 (20130101) C12N 15/86 (20130101) C12N 15/111 (20130101) C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073872 | Demirci et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Brigham and Women`s Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Utkan Demirci (Cambridge, Massachusetts); Xiaohui Zhang (Shaanxi, China PRC); Emre Kayaalp (Tenafly, New Jersey); Hooman Safaee (Mississauga, Canada); Savas Tasoglu (Cambridge, Massachusetts); Paolo Nicolas Catalano (Ciudad de Buenos Aires, Argentina) |
| ABSTRACT | A method for sorting motile cells includes introducing an initial population of motile cells into an inlet port of a microfluidic channel, the initial population of motile cells having a first average motility; incubating the population of motile cells in the microfluidic channel; and collecting a sorted population of motile cells at an outlet port of the microfluidic channel. The sorted population of motile cells has a second average motility higher than the first average motility. |
| FILED | Friday, August 20, 2021 |
| APPL NO | 17/407609 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502746 (20130101) B01L 3/502761 (20130101) B01L 2200/0652 (20130101) B01L 2200/0694 (20130101) B01L 2300/0654 (20130101) B01L 2300/0816 (20130101) B01L 2300/0858 (20130101) B01L 2300/0887 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) C12M 33/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0612 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1484 (20130101) G01N 33/689 (20130101) G01N 33/5029 (20130101) G01N 33/6893 (20130101) G01N 2015/149 (20130101) G01N 2800/367 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073887 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David R. Liu (Cambridge, Massachusetts); David B. Thompson (Cambridge, Massachusetts); Jeffrey L. Bessen (Cambridge, Massachusetts) |
| ABSTRACT | Some aspects of the present disclosure provide methods for evolving recombinases to recognize target sequences that differ from the canonical recognition sequences. Some aspects of this disclosure provide evolved recombinases, e.g., recombinases that bind and recombine naturally-occurring target sequences, such as, e.g., target sequences within the human Rosa26 locus. Methods for using such recombinases for genetically engineering nucleic acid molecules in vitro and in vivo are also provided. Some aspects of this disclosure also provide libraries and screening methods for assessing the target site preferences of recombinases, as well as methods for selecting recombinases that bind and recombine a non-canonical target sequence with high specificity. |
| FILED | Tuesday, August 10, 2021 |
| APPL NO | 17/398870 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1241 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 15/907 (20130101) C12N 15/1037 (20130101) C12N 15/1058 (20130101) C12N 15/1093 (20130101) C12N 2795/00021 (20130101) C12N 2795/00043 (20130101) C12N 2795/14121 (20130101) C12N 2795/14143 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) Enzymes C12Y 207/07 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 30/04 (20130101) C40B 40/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073897 | GREEN |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexander A. GREEN (Boston, Massachusetts) |
| ABSTRACT | Provided herein, in some embodiments, are artificial ribosomes that synthesize nonribosomal peptides, polyketides, and fatty acids with full control over peptide sequence. Also provided herein are methods for programmed synthesis of nonribosomal peptides, polyketides, and fatty acids. In particular, provided herein are methods for scalable synthesis of a wide range of antibacterial, antifungal, antiviral, and anticancer compounds. |
| FILED | Tuesday, October 26, 2021 |
| APPL NO | 17/510900 |
| CURRENT CPC | Peptides C07K 14/005 (20130101) C07K 14/47 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/93 (20130101) Original (OR) Class C12N 15/113 (20130101) C12N 2740/10022 (20130101) C12N 2740/16022 (20130101) C12N 2740/16222 (20130101) C12N 2795/10322 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/6409 (20130101) C12P 21/02 (20130101) Enzymes C12Y 603/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220074447 | SCHOENHOLTZ et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRITON SYSTEMS, INC. (Chelmsford, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen SCHOENHOLTZ (Wilmington, Massachusetts); Tyson LAWRENCE (Highlands Ranch, Colorado); Jennifer SMITH (Ayer, Massachusetts); Rafael MANDUJANO (Arlington, Massachusetts); Grant DREW (Sanbornton, New Hampshire) |
| ABSTRACT | Disclosed are bearing assemblies including a compliant layer within a mounting socket for reducing wear of the bearing. |
| FILED | Friday, September 10, 2021 |
| APPL NO | 17/472503 |
| CURRENT CPC | Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 23/045 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220074631 | Pei et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Qibing Pei (Calabasas, California); Yuan Meng (Los Angeles, California) |
| ABSTRACT | A device comprising one or more heat transfer laminates each including an electrode, a first dielectric layer on a first side of the electrode, and a second dielectric layer on a second side of the electrode; a plurality of flexible electrocaloric elements, each of the flexible electrocaloric elements including an electrocaloric material layer, a flexible electrode layer on the electrocaloric layer, one or more fixed portions each attached to one of heat transfer laminates, and a movable portion that is movable with respect to the one of the heat transfer laminates. |
| FILED | Friday, September 10, 2021 |
| APPL NO | 17/472182 |
| CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 21/00 (20130101) Original (OR) Class F25B 2321/001 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220074722 | Bailey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert A. Bailey (Avon, Indiana); James T. Erdmann (Indianapolis, Indiana); Stephen A. Streib (Greenfield, Indiana); Armando Guerrero (Columbus, Indiana); Roy P. Mcmahon (Indianapolis, Indiana); Jessica R. Deherdt (Indianapolis, Indiana) |
| ABSTRACT | A munitions rack includes a munitions rack structure that houses multiple compact ejectors. The structure includes a pair of internal longitudinal ribs, inboard of a pair of external longitudinal ribs. A spine of the munitions rack structure links all the ribs, and the munitions rack structure may be formed out of a single piece of material. The ribs define a pair of side recesses on the port and starboard sides of the bomb, which each may be further subdivided into a forward pocket and an aft pocket. Removable ejectors are located in the pockets. The ejectors may receive pressurized gas from pressurized gas source(s) located outside of the ejectors. The ejectors may each have multiple forward pistons and multiple aft pistons. The ejectors may include pitch control valving to control the relative amounts of pressurized gas sent to the forward piston(s) and aft piston(s). |
| FILED | Monday, May 24, 2021 |
| APPL NO | 17/328107 |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 1/04 (20130101) B64D 7/08 (20130101) Weapon Sights; Aiming F41G 7/007 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 39/28 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220074907 | Rubenstein |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | H. Mitchell Rubenstein (Beavercreek, Ohio) |
| ABSTRACT | A method for reducing the variability, as measured by relative standard deviation (RSD), of an analytical testing technique is provided. This improvement in RSD improves the confidence in the values obtained during field testing. The method includes incorporating a focusing agent into the sampling media, which permits providing sampling media such as thermal desorption tubes preloaded with the focusing agent. |
| FILED | Wednesday, July 21, 2021 |
| APPL NO | 17/381810 |
| CURRENT CPC | Separation B01D 53/025 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/405 (20130101) G01N 30/08 (20130101) G01N 30/7206 (20130101) G01N 30/8668 (20130101) G01N 33/0006 (20130101) G01N 33/0057 (20130101) Original (OR) Class G01N 2030/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220074936 | CARTWRIGHT et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Mark J. CARTWRIGHT (West Newton, Massachusetts); Nazita GAMINI (Somerville, Massachusetts); Donald E. INGBER (Boston, Massachusetts); Martin M. ROTTMAN (La Celle-Saint-Cloud, France); Michael SUPER (Lexington, Massachusetts); Julie A. TOMOLONIS (Houston, Texas); Karen A. SINCLAIR (Cambridge, Massachusetts) |
| ABSTRACT | The disclosure provides methods, compositions, and kits for enhanced detection of microbes in samples and monitoring of antimicrobial activity in a subject. |
| FILED | Wednesday, November 17, 2021 |
| APPL NO | 17/528456 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5695 (20130101) G01N 33/56911 (20130101) Original (OR) Class G01N 33/56961 (20130101) G01N 2333/4724 (20130101) G01N 2400/00 (20130101) G01N 2800/26 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220074946 | WOODBURY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Neal WOODBURY (Tempe, Arizona); Stephen JOHNSTON (Tempe, Arizona); Phillip STAFFORD (Phoenix, Arizona) |
| ABSTRACT | The present application provides arrays for use in immunosignaturing and quality control of such arrays. Also disclosed are peptide arrays and uses thereof for diagnostics, therapeutics and research. |
| FILED | Monday, July 19, 2021 |
| APPL NO | 17/305975 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6845 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
20220075079 — NAVIGATION WITH DIFFERENTIAL CARRIER PHASE MEASUREMENT FROM LOW EARTH ORBIT SATELLITES
| US 20220075079 | KASSAS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Zak KASSAS (Irvine, California); Joe KHALIFE (Irvine, California); Mohammad NEINAVAIE (Irvine, California) |
| ABSTRACT | Systems, device configurations, and processes are provided for navigation and determination of navigation observables based on low Earth orbit (LEO) satellite signals. A method for navigation includes using differential carrier phase measurement of LEO signals including correction of position estimates using integer ambiguity resolution and double difference carrier phase determinations. Frameworks described herein can use a computationally efficient integer ambiguity resolution to reduce the size of the integer least squares (ILS) determination. The framework may include a joint probability density function (pdf) of the megaconstellation LEO satellites' azimuth and elevation angle to characterize a LEO system. Embodiments are also directed to correction of ambiguities of carrier phase differential (CD)-low Earth orbit (LEO) (CD-LEO) measurements that may utilize a base and a rover without requiring prior knowledge of rover position. |
| FILED | Friday, July 02, 2021 |
| APPL NO | 17/367025 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/44 (20130101) Original (OR) Class G01S 19/393 (20190801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220075114 | Frankel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ciena Corporation (Hanover, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Y. Frankel (Bethesda, Maryland); Vladimir Pelekhaty (Baltimore, Maryland); Sadok Aouini (Gatineau, Canada) |
| ABSTRACT | A Photonic Integrated Circuit (PIC) includes N Ring and Disk type Microstructures (RDMs), N is an integer and greater than 1; at least one spare RDM, wherein each RDM operates spectrally in a periodic nature and has its spectral operation vary by temperature; and circuitry configured to handoff any of the N RDMs and the at least one spare RDM for spectral operation based on a current temperature. For the handoff, the at least one spare RDM is unlocked spectrally and is tuned and locked to a frequency of interest of a current RDM based on the temperature, and the current RDM is unlocked. |
| FILED | Wednesday, September 01, 2021 |
| APPL NO | 17/463865 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/12007 (20130101) Original (OR) Class G02B 6/29343 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220075237 | MITTAL et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sunil MITTAL (Rockville, Maryland); Mohammad HAFEZI (Washington, District of Columbia); Venkata Vikram ORRE (College Park, Maryland) |
| ABSTRACT | A topological photonic system configured as a robust source of indistinguishable photons pairs with tunable spectral correlations. The system includes a two-dimensional silicon-photonic ring resonator array configured to implement an anomalous-quantum Hall model that exhibits topologically robust edge states. Linear dispersion of the edge states ensures efficient and robust phase matching and tunability of the spectral bandwidth of photon pairs generated via spontaneous four-wave mixing. Spectral tunability is manifested in the temporal correlations in the Hong-Ou-Mandel interference between photons. The generated photon pairs are energy-time entangled. |
| FILED | Friday, May 21, 2021 |
| APPL NO | 17/326971 |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/365 (20130101) G02F 1/3526 (20130101) Original (OR) Class G02F 1/3536 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220075435 | Bose et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pradip Bose (Yorktown Heights, New York); Alper Buyuktosunoglu (White Plains, New York); Pierce I-Jen Chuang (Briarcliff Manor, New York); Phillip John Restle (Katonah, New York); Christos Vezyrtzis (New Rochelle, New York) |
| ABSTRACT | Techniques facilitating voltage management via on-chip sensors are provided. In one example, a computer-implemented method can comprise measuring, by a first processor core, power supply information. The computer-implemented method can also comprise measuring, by the first processor core, a value of an electrical current generated by the first processor core. Further, the computer-implemented method can comprise applying, by the first processor core, a mitigation technique at the first processor core in response to a determination that a combination of the power supply noise information and the value of the electrical current indicates a presence of a voltage noise at the first processor core. |
| FILED | Friday, June 25, 2021 |
| APPL NO | 17/359153 |
| CURRENT CPC | Electric Digital Data Processing G06F 1/28 (20130101) G06F 1/305 (20130101) G06F 1/3206 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220076046 | Huber et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Huber (Jessup, Maryland); Lena Franklin (Rockville, Maryland); Jake Griffiths (Sykesville, Maryland); William Scharpf (Huntingtown, Maryland) |
| ABSTRACT | A method of extracting high-frequency temporal information from images or video recorded with a rolling shutter-based imager includes the steps of acquiring image data using a rolling shutter-based imager; and extracting time-domain frequency information from the image based on two or more lines of pixels in the image. |
| FILED | Tuesday, September 07, 2021 |
| APPL NO | 17/468616 |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/4642 (20130101) Original (OR) Class G06K 9/6202 (20130101) Pictorial Communication, e.g Television H04N 5/3532 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220076111 | Marez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Diego Marez (Oceanside, California); John David Reeder (San Diego, California) |
| ABSTRACT | A self-supervised machine-learning system identifies whether an intermittent signal is present. The system includes a receiver, an encoding neural network, a decoding neural network, and a gating neural network. The receiver detects radiation and from the detected radiation generates a sampled sequence including sampled values describing the intermittent signal and noise. The encoding neural network is trained to compress each window over the sampled sequence into a respective context vector having a fixed dimension less than an incoming dimension of the window. The decoding neural network is trained to decompress the respective context vector for each window into an interim sequence describing the intermittent signal while suppressing the noise. The gating neural network is trained to produce a confidence sequence from a sigmoidal output based on the interim sequence. Despite the noise, the confidence sequence identifies whether the intermittent signal is present in each sampled value in the sampled sequence. |
| FILED | Tuesday, September 08, 2020 |
| APPL NO | 17/014475 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/021 (20130101) G01S 7/417 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220076403 | Rutberg |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CAMX Power LLC (Lexington, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Rutberg (Arlington, Massachusetts) |
| ABSTRACT | Non-contact sensors include an image sensor configured to capture image data of a portion of a surface of a rotatable shaft and an electronic control unit communicatively coupled to the image sensor. The electronic control unit is configured to receive image data having a plurality of frames from the image sensor and store the image data in a memory component of the electronic control unit, determine a transformation in image space between one or more surface features that appear in a first frame of the image data and the same one or more surface features that appear in a second frame of the image data, determine a rotational position of the rotatable shaft at a time of capture of the second frame of the image data based on the transformation and a quantitatively characterized relationship between image space and object space, and store the rotational position of the rotatable shaft. |
| FILED | Tuesday, February 23, 2021 |
| APPL NO | 17/183068 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 1/0007 (20130101) G06T 7/0004 (20130101) Original (OR) Class G06T 7/40 (20130101) G06T 7/70 (20170101) G06T 2207/30164 (20130101) Pictorial Communication, e.g Television H04N 5/2256 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220076787 | Ellington et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew Ellington (Austin, Texas); Austin Cole (Austin, Texas); Raghav Shroff (Austin, Texas); Ross Thyer (Austin, Texas) |
| ABSTRACT | A computer-implemented method of training a neural network to improve a characteristic of a protein comprises collecting a set of amino acid sequences from a database, compiling each amino acid sequence into a three-dimensional crystallographic structure of a folded protein, training a neural network with a subset of the three-dimensional crystallographic structures, identifying, with the neural network, a candidate residue to mutate in a target protein, and identifying, with the neural network, a predicted amino acid residue to substitute for the candidate residue, to produce a mutated protein, wherein the mutated protein demonstrates an improvement in a characteristic over the target protein. A system for improving a characteristic of a protein is also described. Improved blue fluorescent proteins generated using the system are also described. |
| FILED | Wednesday, October 27, 2021 |
| APPL NO | 17/512116 |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) G16B 30/00 (20190201) Original (OR) Class G16B 40/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220076857 | SAFFMAN |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark SAFFMAN (Madison, Wisconsin) |
| ABSTRACT | A system and method for controlling particles using projected light are provided. In some aspects, the method includes generating a beam of light using an optical source, and directing the beam of light to a beam filter comprising a first mask, a first lens, a second mask, and a second lens. The method also includes forming an optical pattern using the beam filter, and projecting the optical pattern on a plurality of particles to control their locations in space. |
| FILED | Friday, January 03, 2020 |
| APPL NO | 17/420542 |
| CURRENT CPC | Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220077371 | Howe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HOWE INDUSTRIES LLC (Scottsdale, Arizona) |
| ASSIGNEE(S) | HOWE INDUSTRIES LLC (Scottsdale, Arizona) |
| INVENTOR(S) | Troy Michael Howe (Tempe, Arizona); Steven Daniel Howe (Mesa, Arizona) |
| ABSTRACT | A thermoelectric converter including a thermoelectric generator and a radiation source. The thermoelectric generator includes a hot source, a cold source, n-type material, and p-type material. The radiation source emits ionizing radiation that increases electrical conductivity. Also detailed is a method of using radiation to reach high efficiency with a thermoelectric converter that includes providing a thermoelectric generator and a radiation source, with the thermoelectric generator including a hot source, a cold source, n-type material, and p-type material, and emitting ionizing radiation with the radiation source to increase the electrical conductivity which strips electrons in the n-type material, the p-type material, or both the n-type material and p-type material from their nuclei with the electrons then free to move within the material. |
| FILED | Wednesday, March 10, 2021 |
| APPL NO | 17/198040 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/30 (20130101) Original (OR) Class H01L 35/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220077407 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Florida State University State Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhibin Yu (Tallahassee, Florida); Junqiang Li (Tallahassee, Florida); Xin Shan (Tallahassee, Florida) |
| ABSTRACT | An emissive perovskite ternary composite thin film comprising a perovskite material, an ionic-conducting polymer and an ionic-insulating polymer is provided. Additionally, a single-layer LEDs is described using a composite thin film of organometal halide perovskite (Pero), an ionic-conducting polymer (ICP) and an ionic-insulating polymer (IIP). The LEDs with Pero-ICP-IIP composite thin films exhibit a low turn-on voltage of about 1.9V (defined at 1 cd m−2 luminance) and a luminance of about 600,000 cd m−2. |
| FILED | Thursday, October 14, 2021 |
| APPL NO | 17/501704 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/004 (20130101) H01L 51/0077 (20130101) Original (OR) Class H01L 51/5032 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220077506 | Eskra et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Eskra Technical Products, Inc. (Saukville, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael David Eskra (Saukville, Wisconsin); Paula Margaret Ralston (Frederick, Maryland); Richard Thomas Johnson (Howard, Colorado) |
| ABSTRACT | A bipolar lead acid battery with increased energy density is provided. The battery includes a number of lead acid wafer cell that each comprise a negative electrode having a negative electrode plate and a negative active material positioned on the negative electrode plate, as well as a positive electrode having a positive electrode plate and a positive active material positioned on the positive electrode plate. The positive electrode plate comprises a metal foil with a conductive film thereon, such as a titanium foil or substrate with a titanium silicide coating thereon. The lead acid wafer cell also includes a separator between the negative and positive electrodes, wherein the separator includes an electrolyte for transferring charge between the negative and positive electrodes. |
| FILED | Monday, June 28, 2021 |
| APPL NO | 17/304863 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/14 (20130101) H01M 4/624 (20130101) H01M 4/661 (20130101) H01M 4/667 (20130101) H01M 10/10 (20130101) H01M 10/18 (20130101) Original (OR) Class H01M 50/172 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220077848 | YU et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yao YU (San Mateo, California); Matteo RINALDI (Boston, Massachusetts) |
| ABSTRACT | Tunable delay circuit devices have an input port, an output port, at least three parallel paths connecting the input port and the output port, on each path, an input switch and an output switch, and on each path, a plurality of shunt resonant tanks connected between the input switch and the output switch, each shunt resonant tank periodically chargeable from the input port and dischargeable to the output port by operation of the input switch and the output switch. |
| FILED | Tuesday, July 06, 2021 |
| APPL NO | 17/368173 |
| CURRENT CPC | Impedance Networks, e.g Resonant Circuits; Resonators H03H 9/15 (20130101) Pulse Technique H03K 5/14 (20130101) Original (OR) Class H03K 5/145 (20130101) H03K 2005/00019 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220077952 | PAGE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE MITRE CORPORATION (McLean, Virginia) |
| ASSIGNEE(S) | THE MITRE CORPORATION (McLean, Virginia) |
| INVENTOR(S) | Mark A. PAGE (McLean, Virginia); Steen A. PARL (McLean, Virginia); Scott ZHAO (McLean, Virginia) |
| ABSTRACT | A communications system and methods for covert communications are provided. A first transmitter that transmits an information carrying signal to a target receiver, a second transmitter and a third transmitter transmit jamming signals to the target receiver, such that the information carrying signals and the jamming signals are interleaved when received by the target receiver The information carrying signals and the jamming signals can be at least partially overlapping by an eavesdropper. |
| FILED | Thursday, July 09, 2020 |
| APPL NO | 16/925136 |
| CURRENT CPC | Secret Communication; Jamming of Communication H04K 3/65 (20130101) H04K 3/825 (20130101) Original (OR) Class H04K 2203/32 (20130101) H04K 2203/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220078908 | Johnson, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alan T Johnson, Jr. (Philadelphia, Pennsylvania); Rajatesh R Gudibande (Philadelphia, Pennsylvania); Zhengqing John Qi (Albany, New York) |
| ABSTRACT | The present invention provides methods for fabricating graphene workpieces. The present invention also provides for products produced by the methods of the present invention and for apparatuses used to perform the methods of the present invention. |
| FILED | Thursday, March 25, 2021 |
| APPL NO | 17/212092 |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/32 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/1606 (20130101) H01L 29/78684 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/09 (20130101) Original (OR) Class H05K 1/0306 (20130101) H05K 3/06 (20130101) H05K 3/20 (20130101) H05K 3/125 (20130101) H05K 3/1216 (20130101) H05K 3/1275 (20130101) H05K 2201/0323 (20130101) H05K 2203/1338 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20220072135 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Administrators of the Tulane Educational Fund (New Orleans, Louisiana); Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Donghui Zhang (Baton Rouge, Louisiana); Vijay T. John (Destrehan, Louisiana); Yueheng Zhang (New Orleans, Louisiana); Sunting Xuan (Albany, California) |
| ABSTRACT | A variety of hydrophobically modified polypeptoids are provided. The hydrophobically modified polypeptoids can include a polyimide backbone having a random copolymer of two or more different types of repeat units, where one or more of the repeat units have nitrogen atom having a hydrophobic substituent attached thereto. Methods of making the hydrophobically modified polypeptoids are also provided, as well as uses of the hydrophobically modified polypeptoids, for example in liposomal drug delivery. |
| FILED | Wednesday, August 18, 2021 |
| APPL NO | 17/405219 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/18 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 47/34 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072509 | Thomas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Kara E. Thomas (Newport Beach, California); Sarah C. Finkeldei (Irvine, California); Mikael Nilsson (Dickson ACT, Australia); Dmitry A. Fishman (Aliso Viejo, California) |
| ABSTRACT | A method for separating metal ions from a liquid includes a step of providing a solution having metal-containing ions and associated negative counter ions in a liquid. The metal-containing ions are contacted with a dendrimer to form solid particles of metal-containing ion-dendrimer complexes. The solid particles of metal-containing ion-dendrimer complexes are separated from the solution. |
| FILED | Wednesday, September 08, 2021 |
| APPL NO | 17/469232 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/265 (20130101) Original (OR) Class B01J 45/00 (20130101) B01J 2523/397 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/42 (20130101) C02F 2101/006 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 60/026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072529 | LEE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York) |
| ASSIGNEE(S) | RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York) |
| INVENTOR(S) | Sangwoo LEE (Cohoes, New York); Chulsung BAE (Cohoes, New York); Musashi J. BRIEM (Troy, New York); Sungmin PARK (Troy, New York) |
| ABSTRACT | The anion exchange membranes exhibit enhanced chemical stability and ion conductivity when compared with traditional styrene-based alkaline anion exchange membranes. A copolymer backbone is polymerized from a reaction medium that includes a diphenylalkylene and an alkadiene. The copolymer includes a plurality of pendant phenyl groups. The diphenyl groups on the polymer backbone are functionalized with one or more haloalkylated precursor substrates. The terminal halide from the precursor substrate can then be substituted with a desired ionic group. The diphenylethylene-based alkaline anion exchange membranes lack the α-hydrogens sharing tertiary carbons with phenyl groups from polystyrene or styrene-based precursor polymers, resulting in higher chemical stability. The ionic groups are also apart from each other by about 3 to 6 carbons in the polymer backbone, enhancing ion conductivity. These membrane are advantageous for use in fuel cells, electrolyzers employing hydrogen, ion separations, etc. |
| FILED | Tuesday, November 16, 2021 |
| APPL NO | 17/527652 |
| CURRENT CPC | Separation B01D 61/44 (20130101) B01D 71/06 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 41/07 (20170101) Original (OR) Class B01J 41/14 (20130101) B01J 47/12 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/469 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 212/32 (20130101) C08F 2810/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/2287 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073350 | GOGOTSI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yury GOGOTSI (Warminster, Pennsylvania); Xu XIAO (Philadelphia, Pennsylvania); Hao WANG (Philadelphia, Pennsylvania); Patrick URBANKOWSKI (Philadelphia, Pennsylvania) |
| ABSTRACT | The present disclosure relates to the methods of preparing two-dimensional arrays of nanocrystalline metal carbide and metal nitride compositions and the compositions and devices derived from these methods and compositions. |
| FILED | Thursday, December 19, 2019 |
| APPL NO | 17/419803 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 21/062 (20130101) C01B 21/076 (20130101) C01B 21/0617 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/58 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073399 | Gangloff, JR. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John J. Gangloff, JR. (Middletown, Connecticut); Paul Sheedy (Bolton, Connecticut); Justin B. Alms (Coventry, Connecticut); John E. Holowczak (South Windsor, Connecticut); Daniel A. Mosher (Glastonbury, Connecticut) |
| ABSTRACT | A method of forming a part includes forming a glass-ceramic matrix composite material to form a pre-consolidated feedstock sheet with a pre-determined shape. The pre-consolidated feedstock sheet is sectioned into a first piece of pre-consolidated feedstock sheet and a second piece of pre-consolidated feedstock sheet. The first piece of pre-consolidated feedstock sheet and a second piece of pre-consolidated feedstock sheet are assembled with a second piece of pre-consolidated feedstock sheet to form a composite layup. The first piece of pre-consolidated feedstock sheet and the second piece of pre-consolidated feedstock sheet are joined by compressing the composite layup to form a glass-ceramic matrix composite part. |
| FILED | Friday, September 04, 2020 |
| APPL NO | 17/012351 |
| CURRENT CPC | Manufacture, Shaping, or Supplementary Processes C03B 19/09 (20130101) C03B 23/0302 (20130101) Original (OR) Class C03B 2215/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073432 | Chandrasekaran et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Swetha Chandrasekaran (Dublin, California); James T. Cahill (Livermore, California); Wyatt L. Du Frane (Livermore, California); Joshua D. Kuntz (Livermore, California); Richard L. Landingham (Livermore, California); Ryan Lu (Daly City, California); Marcus A. Worsley (Hayward, California) |
| ABSTRACT | An ink, and products formed from the ink, formulated at least in part from ceramic particles. The ink is formulated so that it can be used in additive manufacturing processes to form three-dimensional printed bodies. The three-dimensional printed bodies can have graded density and can be infiltrated by an infiltration material. |
| FILED | Wednesday, September 09, 2020 |
| APPL NO | 17/015403 |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 70/00 (20141201) B33Y 80/00 (20141201) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/6263 (20130101) C04B 35/6264 (20130101) C04B 35/62218 (20130101) Original (OR) Class C04B 35/63448 (20130101) C04B 2235/3813 (20130101) C04B 2235/3821 (20130101) C04B 2235/3839 (20130101) C04B 2235/5436 (20130101) C04B 2235/5445 (20130101) C04B 2235/6026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073439 | WEAVER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jason F. WEAVER (Gainesville, Florida); Yingxue BIAN (Golden, Colorado) |
| ABSTRACT | Methods of converting ethane to ethylene at relatively low temperatures are described. Ir02-based catalysts are used in the conversion. Methods of converting a base gas to a first gas by exposing the base gas to an IrO2-based catalyst and forming the first gas are described. The base gas can be an alkane. The first gas can include an alkene, an alkyne, an alcohol, an aldehyde, or combinations thereof. |
| FILED | Wednesday, November 17, 2021 |
| APPL NO | 17/528675 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/468 (20130101) Acyclic or Carbocyclic Compounds C07C 5/3337 (20130101) Original (OR) Class C07C 11/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073517 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jian Li (Tempe, Arizona); Jiang Wu (Chandler, Arizona) |
| ABSTRACT | Compounds of General Formula I may act as thermally activated delayed fluorescent emitters in organic electroluminescent devices. Compounds of General Formula I have donor and acceptor groups part of the same conjugated system. Devices incorporating compounds of General Formula I may have higher EQE and longer material lifetimes. |
| FILED | Thursday, September 09, 2021 |
| APPL NO | 17/470092 |
| CURRENT CPC | Heterocyclic Compounds C07D 471/14 (20130101) Original (OR) Class C07D 471/22 (20130101) C07D 491/22 (20130101) C07D 491/147 (20130101) C07D 495/14 (20130101) C07D 495/22 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0072 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073551 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jian Li (Tempe, Arizona); Jiang Wu (Chandler, Arizona) |
| ABSTRACT | Compounds of General formula I and General Formula II have substituents which may result in a non-planar configuration. This molecular geometry may be effective in reducing excimer formation. The compounds described herein may therefore have improved blue color purity. The compounds have utility in light emitting diodes and light emitting devices. |
| FILED | Thursday, September 09, 2021 |
| APPL NO | 17/470125 |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/006 (20130101) C07F 15/0086 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0087 (20130101) H01L 51/5016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220074019 | Verba et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Department of Energy (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Circe Verba (Albany, Oregon); Mark L. McKoy (Bruceton Mills, West Virginia); Thomas J. Tarka (Pittsburgh, Pennsylvania); Scott Montross (Albany, Oregon); Jonathan Yang (Corvallis, Oregon) |
| ABSTRACT | One or more embodiments relates to a process for extracting Rare Earth Elements (REEs) from REE-bearing underclays, claystones, shales, coal-mining waste, and waste coal. In at least one embodiment the process includes contacting the REE-bearing underclays, claystones, shales, coal-mining waste, and waste coal with an Organic Acid Solution (OAS) comprising at least one organic acid and at least one ionic salt at a predetermined ambient temperature and predetermined pH; and separating the REE from the REE-bearing underclays, claystones, shales, coal-mining waste, and waste coal, forming REE+Yttrium (REY) concentrate. |
| FILED | Friday, September 04, 2020 |
| APPL NO | 17/012858 |
| CURRENT CPC | Production and Refining of Metals; Pretreatment of Raw Materials C22B 3/22 (20130101) C22B 3/165 (20130101) Original (OR) Class C22B 59/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220074324 | Boyce-Erickson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Grey C. Boyce-Erickson (Minneapolis, Minnesota); James D. Van de Ven (Minneapolis, Minnesota); Thomas R. Chase (Minneapolis, Minnesota) |
| ABSTRACT | A hydraulic pump-motor includes a cylinder block including a plurality of fluid chambers, a piston in each of the fluid chambers, a cam, a fixed valve area profile, and a timing adjustment actuator. The cam includes a cam surface that engages the pistons and drives movement of the pistons relative to the fluid chambers in response to relative rotation between the cam and the fluid chambers. The fixed valve area profile is configured to control fluid flows between the fluid chambers and first and second ports. The timing adjustment actuator is configured to adjust an angular orientation of the fixed valve area profile relative to an angular orientation of the cam based on a pressure differential between a pressure at the first port and a pressure at the second port. |
| FILED | Friday, September 10, 2021 |
| APPL NO | 17/471645 |
| CURRENT CPC | Cyclically Operating Valves for Machines or Engines F01L 1/3442 (20130101) Original (OR) Class F01L 2001/3445 (20130101) F01L 2001/34423 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220074639 | Cahill et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James T. Cahill (Livermore, California); Swetha Chandrasekaran (Dublin, California); Wyatt L. Du Frane (Livermore, California); Joshua D. Kuntz (Livermore, California); Richard L. Landingham (Livermore, California); Ryan Lu (Daly City, California); Christopher M. Spadaccini (Oakland, California); Amy Wat (Oakland, California); Seth E. Watts (Collingswood, New Jersey); Marcus A Worsley (Hayward, California) |
| ABSTRACT | A semi-passive cooling system for a component exposed to a fluid flow utilizes a hierarchical vasculature and a sacrificial transpirant to cool the component. The component includes a body that defines a transpirant reservoir and the hierarchical vasculature. The transpirant is configured to transition between a solid phase and a vapor phase over an operating temperature range of the component. |
| FILED | Tuesday, September 08, 2020 |
| APPL NO | 17/014756 |
| CURRENT CPC | Refrigerators; Cold Rooms; Ice-boxes; Cooling or Freezing Apparatus Not Otherwise Provided for F25D 3/00 (20130101) F25D 7/00 (20130101) Original (OR) Class F25D 2303/084 (20130101) F25D 2303/08222 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220074766 | GEE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard H. GEE (Livermore, California); Amitesh MAITI (San Ramon, California); Henry E. REINSTEIN (Livermore, California); Alexander David WILSON (Danville, California); Peter J. ZISCHKA (Livermore, California) |
| ABSTRACT | A system for determining particle size of a quantity of a sample material contained in a sample material holder is disclosed, where the sample material is made up a plurality of the particles. The system may incorporate a pressure regulating subsystem for receiving a first pressurized airflow signal and regulating the first pressurized airflow signal to a second pressurized airflow signal having a pressure lower than the first pressurized airflow signal, the second pressurized airflow signal configured to be input to a first end of the sample material holder. A mass airflow transducer may be incorporated for determining a flow rate representing an air flow value entering the sample material holder. A control module uses the air flow value in combination with the pressure differential value and mathematically determining a dimension of the particles making up the sample material. |
| FILED | Thursday, September 10, 2020 |
| APPL NO | 17/017271 |
| CURRENT CPC | Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 1/88 (20130101) G01F 1/363 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220074779 | SIEVERS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Andrew SIEVERS (Golden, Colorado); James Joseph LISCHESKE (Arvada, Colorado) |
| ABSTRACT | Described herein are systems and methods for determining the volume of liquid and/or solids present in a vessel by flowing gas to or from an accumulator vessel and using the ideal gas law to determine the volume of gas (e.g., void space) present in the vessel. Advantageously, the described systems and methods and nonintrusive and may be useful for applications in which the level of liquid/solids in the vessel are unstable or where traditional volumetric measurements would interfere with internal processes, such as agitation. |
| FILED | Tuesday, September 07, 2021 |
| APPL NO | 17/467689 |
| CURRENT CPC | Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 23/18 (20130101) Original (OR) Class G01F 23/0076 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220074926 | Beer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | N. Reginald Beer (Pleasanton, California); Steven W. Bond (Livermore, California) |
| ABSTRACT | The disclosed technology includes a planar device for performing multiple biochemical assays at the same time, or nearly the same time. Each assay may include a biosample including a biochemical, enzyme, DNA, and/or any other biochemical or biological sample. Each assay may include one or more tags including dyes and/or other chemicals/reagents whose optical characteristics change based on chemical characteristics of the biological sample being tested. Each assay may be optically pumped to cause one or more of luminescence, phosphorescence, or fluorescence of the assay that may be detected by one or more optical detectors. For example, an assay may include two tags and a biosample. Each tag may be pumped by different wavelengths of light and may produce different wavelengths of light that is filtered and detected by one or more detectors. The pump wavelengths may be different from one another and different from the produced wavelengths. |
| FILED | Wednesday, November 17, 2021 |
| APPL NO | 17/529249 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/64 (20130101) G01N 33/521 (20130101) G01N 33/525 (20130101) Original (OR) Class G01N 33/54366 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220076159 | Owen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven J. Owen (San Diego, California); Timothy Shead (Albuquerque, New Mexico); Shawn Martin (Sandia Park, New Mexico); Armida J. Carbajal (Albuquerque, New Mexico) |
| ABSTRACT | A method, apparatus, system, and computer program product for generating information for modifying a model. Training data comprising entities, operations for the entities, and a number of mesh quality metrics for meshes generated from modified entities resulting from the operations being performed on the entities are selected by a computer system. A set of machine learning models is trained by the computer system using the training data. The set of machine learning models trained with the training data identifies a number of mesh quality metrics for a set of input entities in a model input into the set of machine learning models. |
| FILED | Thursday, September 10, 2020 |
| APPL NO | 17/016543 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0482 (20130101) G06F 3/04847 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220076854 | Ougouag et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Abderrafi Mohammed El-Amine Ougouag (Idaho Falls, Idaho); Ramazan Sonat Sen (Idaho Falls, Idaho); George W. Griffith (Idaho Falls, Idaho) |
| ABSTRACT | A system for transferring heat from a nuclear reactor comprises a nuclear reactor comprising a nuclear fuel and a reactor vessel surrounding the nuclear reactor and a heat transfer system surrounding the nuclear reactor. The heat transfer system comprises an inner wall surrounding the nuclear reactor vessel, first fins coupled to an outer surface of inner wall, an outer wall between the inner wall and a surrounding environment, and second fins coupled to an inner surface of the outer wall and extending in a volume between the outer surface of the inner wall and the inner surface of the outer wall, the outer surface of the inner wall and the first fins configured to transfer heat from the nuclear reactor core to the second fins and the inner surface of the outer wall by thermal radiation. The heat transfer system may be directly coupled to the nuclear reactor vessel, or may be coupled to an external reflector surrounding the nuclear reactor vessel. Related heat transfer systems and systems for selectively removing heat from a nuclear reactor are disclosed. |
| FILED | Thursday, September 10, 2020 |
| APPL NO | 17/017534 |
| CURRENT CPC | Nuclear Reactors G21C 9/00 (20130101) G21C 15/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220076867 | Parker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David S. Parker (Oak Ridge, Tennessee); Brian C. Sales (Lenoir City, Tennessee); Benjamin S. Conner (Dayton, Ohio); Tribhuwan Pandey (Berchem, Belgium); Andriy Palasyuk (Ames, Iowa); Jun Cui (Ames, Iowa) |
| ABSTRACT | A permanent magnetic composition comprising the formula: (LaxMyNd1-x-y)rFevM′zCo14-v-zBw (1) wherein 0.1≤x<1, 11≤v≤14, 0≤y≤0.3, 0≤z≤0.5, 1.9≤r≤3, 0.1≤(x+y)<1, 11≤(v+z)≤14, and 1.0≤w≤1.1, wherein M represents one or more lanthanide elements other than La and Nd, and M′ represents one or more transition metal elements other than Fe and Co, or M′ represents one or more main group elements other than B; or the permanent magnet may be more particularly described by the formula (LaxNd1-x)rFevCo14-vBw or LaNdFe12Co2B, wherein x, v, and w are defined above. Also described herein are methods for producing the permanent magnet. |
| FILED | Wednesday, September 08, 2021 |
| APPL NO | 17/468913 |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/0577 (20130101) Original (OR) Class H01F 7/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220076898 | Liang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yu Teng Liang (Chicago, Illinois); Baiju K. Vijayan (Kerala, India); Kimberly A. Gray (Evanston, Illinois); Mark C. Hersam (Wilmette, Illinois) |
| ABSTRACT | In one aspect of the invention, a dye sensitized solar cell has a counter-electrode including carbon-titania nanocomposite thin films made by forming a carbon-based ink; forming a titania (TiO2) solution; blade-coating a mechanical mixture of the carbon-based ink and the titania solution onto a substrate; and annealing the blade-coated substrate at a first temperature for a first period of time to obtain the carbon-based titania nanocomposite thin films. In certain embodiments, the carbon-based titania nanocomposite thin films may include solvent-exfoliated graphene titania (SEG-TiO2) nanocomposite thin films, or single walled carbon nanotube titania (SWCNT-TiO2) nanocomposite thin films. |
| FILED | Thursday, November 04, 2021 |
| APPL NO | 17/518690 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/18 (20130101) B01J 35/004 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/19 (20170801) C01B 32/192 (20170801) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 23/053 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/52 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/2022 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220076948 | Bush et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Swift Solar Inc. (San Carlos, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kevin Alexander Bush (San Francisco, California); Maximilian Tobias Hoerantner (San Francisco, California); Tomas Leijtens (Redwood City, California) |
| ABSTRACT | Vapor phase transport systems and methods of depositing perovskite films are described. In an embodiment, a deposition method includes feeding a perovskite solution or constituent powder to a vaporizer, followed by vaporization and depositing the constituent vapor as a perovskite film. In an embodiment, a deposition system and method includes vaporizing different perovskite precursors in different vaporization zones at different temperatures, followed by mixing the vaporized precursors to form a constituent vapor, and depositing the constituent vapor as a perovskite film. |
| FILED | Friday, January 15, 2021 |
| APPL NO | 17/150944 |
| CURRENT CPC | Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors B65G 53/16 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/228 (20130101) C23C 14/0694 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 23/066 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02271 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220077336 | TAMBOLI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Adele Clare TAMBOLI (Golden, Colorado); Joel Wheeler AGER, III (Berkeley, California); Emily Lowell WARREN (Golden, Colorado); Calton Junjing KONG (Berkeley, California) |
| ABSTRACT | Described herein are devices and methods utilizing cascade photocatalysis to drive multiple chemical reactions via a series of photoelectrochemical catalysts driven by the conversion of light into current by one or more photovoltaic devices. The described devices and methods are tunable and may be used in conjunction with different reactants and products, including the conversion of carbon dioxide into valuable hydrocarbon products. |
| FILED | Tuesday, September 07, 2021 |
| APPL NO | 17/468316 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/55 (20210101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/043 (20141201) Original (OR) Class H01L 31/048 (20130101) H01L 31/0687 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/9041 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220078130 | Ros-Giralt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Reservoir Labs, Inc. (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jordi Ros-Giralt (Newport Beach, California); Noah Amsel (New York, New York); Sruthi Yellamraju (Germantown, Maryland); Richard A. Lethin (New York, New York) |
| ABSTRACT | A technique is described for quantifying a change in a system parameter in response to a perturbation of another system parameter by identifying a region of influence of the perturbation and by limiting the propagation of the perturbation to the identified region. |
| FILED | Monday, July 12, 2021 |
| APPL NO | 17/373261 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 47/745 (20130101) Original (OR) Class H04L 47/748 (20130101) H04L 47/762 (20130101) H04L 47/781 (20130101) H04L 47/801 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20220071494 | Celinski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Zbigniew Celinski (Colorado Springs, Colorado); Janusz Hankiewicz (Colorado Springs, Colorado); Robert Camley (Colorado Springs, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zbigniew Celinski (Colorado Springs, Colorado); Janusz Hankiewicz (Colorado Springs, Colorado); Robert Camley (Colorado Springs, Colorado) |
| ABSTRACT | Provided are a system and a method for determining the temperature of a body by imaging a hydrogen proton-rich material positioned within the body using nuclear magnetic resonance imaging. A method to increase changes in the MRI signal strength as a function of temperature, thus improving temperature sensitivity, is also provided. The system and method employ polymers having mechanical stability and magnetic image brightness at low temperatures of between 0° C. and −65° C. or high temperatures of between +37° C. and +80° C. |
| FILED | Wednesday, September 08, 2021 |
| APPL NO | 17/469726 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/015 (20130101) Original (OR) Class A61B 5/055 (20130101) A61B 18/0218 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 41/0052 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072529 | LEE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York) |
| ASSIGNEE(S) | RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York) |
| INVENTOR(S) | Sangwoo LEE (Cohoes, New York); Chulsung BAE (Cohoes, New York); Musashi J. BRIEM (Troy, New York); Sungmin PARK (Troy, New York) |
| ABSTRACT | The anion exchange membranes exhibit enhanced chemical stability and ion conductivity when compared with traditional styrene-based alkaline anion exchange membranes. A copolymer backbone is polymerized from a reaction medium that includes a diphenylalkylene and an alkadiene. The copolymer includes a plurality of pendant phenyl groups. The diphenyl groups on the polymer backbone are functionalized with one or more haloalkylated precursor substrates. The terminal halide from the precursor substrate can then be substituted with a desired ionic group. The diphenylethylene-based alkaline anion exchange membranes lack the α-hydrogens sharing tertiary carbons with phenyl groups from polystyrene or styrene-based precursor polymers, resulting in higher chemical stability. The ionic groups are also apart from each other by about 3 to 6 carbons in the polymer backbone, enhancing ion conductivity. These membrane are advantageous for use in fuel cells, electrolyzers employing hydrogen, ion separations, etc. |
| FILED | Tuesday, November 16, 2021 |
| APPL NO | 17/527652 |
| CURRENT CPC | Separation B01D 61/44 (20130101) B01D 71/06 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 41/07 (20170101) Original (OR) Class B01J 41/14 (20130101) B01J 47/12 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/469 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 212/32 (20130101) C08F 2810/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/2287 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072587 | Gealy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ambidextrous Laboratories, Inc. (Emeryville, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Gealy (Berkeley, California); Stephen McKinley (Berkeley, California); Matthew Matl (Fremont, California); Jeffrey Mahler (Berkeley, California); Aaron Smith (Suisun City, California) |
| ABSTRACT | A system and method for item sorting that can include an item selection unit with a robotic pick-and-place machine positioned adjacent to a defined input item region; an item sortation unit comprising a horizontal multi-degree-of-freedom gantry system and an item tote array, wherein the horizontal gantry system is positioned above the item tote array; wherein the item sortation unit further comprises an item holding and depositing system that is coupled to and actuated by the gantry system. The system and method can singulate an item from a collection of items and sort into one of a set of item totes. |
| FILED | Tuesday, September 07, 2021 |
| APPL NO | 17/468220 |
| CURRENT CPC | Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 3/06 (20130101) Original (OR) Class B07C 5/36 (20130101) B07C 2501/0063 (20130101) Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors B65G 1/065 (20130101) B65G 1/1378 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220072753 | McAlpine et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Regents of the University of Minnesota (Menneapolis, Minnesota); U.S. Government as Represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael C. McAlpine (Minneapolis, Minnesota); Ruitao Su (Minneapolis, Minnesota); Steven J. Koester (Edina, Minnesota); Joshua Uzarski (Boston, Massachusetts) |
| ABSTRACT | A printed structure including a plurality of overlying layers of elongate polymeric filaments stacked on a surface of a substrate. The elongate polymeric filaments are stacked on each other along their lengths to form a liquid impermeable, self-supporting wall. The liquid impermeable self-supporting wall forms a wall angle of about 30° to about 90° with respect to a plane of the surface of the substrate. |
| FILED | Wednesday, November 18, 2020 |
| APPL NO | 16/951794 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 35/0805 (20130101) B29C 48/05 (20190201) Original (OR) Class B29C 48/30 (20190201) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Compositions of Macromolecular Compounds C08L 83/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073217 | Iverson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brigham Young University (BYU) (Provo, Utah); University of Dayton Technology Partnerships Office (UDTPO) (Dayton, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brian D. Iverson (Provo, Utah); Rydge B. Mulford (Dayton, Ohio); Matthew R. Jones (Provo, Utah) |
| ABSTRACT | A method includes coupling a radiator panel assembly to a component, and conducting heat from the component via a thermally conductive hinge into at least one base radiator panel in the radiator panel assembly. The method further includes placing the at least one base radiator panel in a position to radiate a fraction of the heat into space through a surface of the at least one base radiator panel, and dynamically varying the position of the at least one base radiator panel to vary an amount of heat loss through the at least one base radiator panel to regulate a temperature of the component. |
| FILED | Friday, September 10, 2021 |
| APPL NO | 17/447358 |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/222 (20130101) B64G 1/503 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220074841 | Westerhoff et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paul K. Westerhoff (Scottsdale, Arizona); Shahnawaz Sinha (Chandler, Arizona); Yuqiang Bi (Chandler, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul K. Westerhoff (Scottsdale, Arizona); Shahnawaz Sinha (Chandler, Arizona); Yuqiang Bi (Chandler, Arizona) |
| ABSTRACT | Quantifying nanobubbles in solution includes combining an indicator with a fluid comprising nanobubbles to yield a first solution, bursting the nanobubbles in the first solution to yield a second solution, and assessing a difference between the first solution and the second solution to yield a concentration of the nanobubbles in the first solution, a concentration of reactive oxygen species in the first solution or the second solution, or both. |
| FILED | Thursday, September 09, 2021 |
| APPL NO | 17/447259 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/06 (20130101) Original (OR) Class G01N 31/22 (20130101) G01N 2015/0011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220074862 | Peterman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | OndaVia, Inc. (Hayward, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark C. Peterman (Fremont, California); Merwan Benhabib (San Francisco, California); Samuel Kleinman (Oakland, California) |
| ABSTRACT | A hand-held microfluidic testing device is provided that includes a housing having a cartridge receiving port, a cartridge for input to the cartridge receiving port having a sample input and a channel, where the channel includes a mixture of Raman-scattering nanoparticles and a calibration solution, where the calibration solution includes chemical compounds capable of interacting with a sample under test input to the cartridge and the Raman-scattering nanoparticles, and an optical detection system in the housing, where the optical detection system is capable of providing an illuminated electric field, where the illuminating electric field is capable of being used for Raman spectroscopy with the Raman-scattering nanoparticles and the calibration solution to analyze the sample under test input to the cartridge. |
| FILED | Tuesday, November 16, 2021 |
| APPL NO | 17/527828 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 2200/0652 (20130101) B01L 2300/087 (20130101) B01L 2300/0636 (20130101) B01L 2300/0654 (20130101) B01L 2300/0681 (20130101) B01L 2300/0867 (20130101) B01L 2400/0418 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/02 (20130101) G01J 3/18 (20130101) G01J 3/44 (20130101) G01J 3/0256 (20130101) G01J 3/0291 (20130101) G01J 3/4412 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/47 (20130101) G01N 21/49 (20130101) G01N 21/63 (20130101) G01N 21/65 (20130101) Original (OR) Class G01N 21/66 (20130101) G01N 21/68 (20130101) G01N 21/658 (20130101) G01N 21/4785 (20130101) G01N 27/44704 (20130101) G01N 27/44791 (20130101) G01N 30/6065 (20130101) G01N 30/6095 (20130101) G01N 33/18 (20130101) G01N 2021/651 (20130101) G01N 2030/0095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20220075079 — NAVIGATION WITH DIFFERENTIAL CARRIER PHASE MEASUREMENT FROM LOW EARTH ORBIT SATELLITES
| US 20220075079 | KASSAS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Zak KASSAS (Irvine, California); Joe KHALIFE (Irvine, California); Mohammad NEINAVAIE (Irvine, California) |
| ABSTRACT | Systems, device configurations, and processes are provided for navigation and determination of navigation observables based on low Earth orbit (LEO) satellite signals. A method for navigation includes using differential carrier phase measurement of LEO signals including correction of position estimates using integer ambiguity resolution and double difference carrier phase determinations. Frameworks described herein can use a computationally efficient integer ambiguity resolution to reduce the size of the integer least squares (ILS) determination. The framework may include a joint probability density function (pdf) of the megaconstellation LEO satellites' azimuth and elevation angle to characterize a LEO system. Embodiments are also directed to correction of ambiguities of carrier phase differential (CD)-low Earth orbit (LEO) (CD-LEO) measurements that may utilize a base and a rover without requiring prior knowledge of rover position. |
| FILED | Friday, July 02, 2021 |
| APPL NO | 17/367025 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/44 (20130101) Original (OR) Class G01S 19/393 (20190801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220075237 | MITTAL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sunil MITTAL (Rockville, Maryland); Mohammad HAFEZI (Washington, District of Columbia); Venkata Vikram ORRE (College Park, Maryland) |
| ABSTRACT | A topological photonic system configured as a robust source of indistinguishable photons pairs with tunable spectral correlations. The system includes a two-dimensional silicon-photonic ring resonator array configured to implement an anomalous-quantum Hall model that exhibits topologically robust edge states. Linear dispersion of the edge states ensures efficient and robust phase matching and tunability of the spectral bandwidth of photon pairs generated via spontaneous four-wave mixing. Spectral tunability is manifested in the temporal correlations in the Hong-Ou-Mandel interference between photons. The generated photon pairs are energy-time entangled. |
| FILED | Friday, May 21, 2021 |
| APPL NO | 17/326971 |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/365 (20130101) G02F 1/3526 (20130101) Original (OR) Class G02F 1/3536 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220075620 | Tu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| INVENTOR(S) | Yicheng Tu (Tampa, Florida); Napath Pitaksirianan (Tampa, Florida) |
| ABSTRACT | Disclosed are various embodiments for computing 2-body statistics on graphics processing units (GPUs). Various types of two-body statistics (2-BS) are regarded as essential components of data analysis in many scientific and computing domains. However, the quadratic complexity of these computations hinders timely processing of data. According, various embodiments of the present disclosure involve parallel algorithms for 2-BS computation on Graphics Processing Units (GPUs). Although the typical 2-BS problems can be summarized into a straightforward parallel computing pattern, traditional wisdom from (general) parallel computing often falls short in delivering the best possible performance. Therefore, various embodiments of the present disclosure involve techniques to decompose 2-BS problems and methods for effective use of computing resources on GPUs. We also develop analytical models that guide users towards the appropriate parameters of a GPU program. Although 2-BS problems share the same core computations, each 2-BS problem however carries its own characteristics that calls for different strategies in code optimization. Accordingly, various embodiments of the present disclosure involve a software framework that automatically generates high-performance GPU code based on a few parameters and short primer code input. |
| FILED | Tuesday, September 14, 2021 |
| APPL NO | 17/474828 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/30043 (20130101) G06F 9/30098 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220075797 | Smilowitz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Karen R. Smilowitz (Evanston, Illinois); George T. Chiampas (Wilmette, Illinois); Taylor G. Hanken (Chicago, Illinois); Rachel G. Lin (Evanston, Illinois); Ryan W. Rose (Evanston, Illinois); Bruno P. Velazquez (Evanston, Illinois); Samuel H. Young (Evanston, Illinois) |
| ABSTRACT | Aspects of the present disclosure relate to data visualization, and more specifically, to technology that automatically visualizes various analytics and predictions generated for mass participation endurance events, or other mass participation events of interest. |
| FILED | Monday, November 15, 2021 |
| APPL NO | 17/526149 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/048 (20130101) G06F 16/26 (20190101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/006 (20130101) G06N 5/02 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/04 (20130101) G06Q 10/06 (20130101) Image Data Processing or Generation, in General G06T 17/05 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220076076 | Morgan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dane Morgan (Middleton, Wisconsin); Ryan Matthew Jacobs (Middleton, Wisconsin); Glenn Palmer (Madison, Wisconsin) |
| ABSTRACT | A computing device computes curve descriptive values to correct an error estimate of a prediction. A predefined number of times, an input dataset is split into a training dataset and a validation dataset, a predictive model and a domain model are trained, the trained predictive model and the trained domain model are validated, a predictive error value, a residual value, and a domain error value are computed, and each value is stored in output data. A domain threshold value is computed from the stored domain error values. Each predictive error value and each residual value stored in the output data is stored in in-domain output data when a respective domain error value is less than or equal to the computed domain threshold value. Curve descriptive values are computed to describe a relationship between the residual values as a function of the prediction error values stored in the in-domain output data. |
| FILED | Tuesday, September 07, 2021 |
| APPL NO | 17/467638 |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6261 (20130101) Original (OR) Class G06K 9/6262 (20130101) Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220076197 | Robertson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Idaho (Moscow, Idaho) |
| ASSIGNEE(S) | University of Idaho (Moscow, Idaho) |
| INVENTOR(S) | Daniel J. Robertson (Moscow, Idaho); Austin R. Bebee (Moscow, Idaho); George Clayton Bennett (Moscow, Idaho); Christopher J. Stubbs (Moscow, Idaho) |
| ABSTRACT | An apparatus and embodiments of a method for using the apparatus to evaluate crop lodging resistance are disclosed. An exemplary apparatus includes a body having a height adjustable force bar coupled thereto and a force sensor configured to detect forces acting on the force bar. Further, the apparatus includes or is configured to be coupled to a movement mechanism that enables movement of the force bar through a plot of stems. The force sensor generates force signals that can be utilized to generate force data. The force data, along with stem density data, stem height data, force bar height data, can be input into one or more models to generate flexural stiffness data. The one or more models can include an Interacting Model and/or a Non-Interacting Model. |
| FILED | Thursday, September 02, 2021 |
| APPL NO | 17/465623 |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00657 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/087 (20130101) Original (OR) Class G06Q 50/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220076779 | Feinberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew P. Feinberg (Baltimore, Maryland); John Goutsias (Baltimore, Maryland); William G. Jenkinson (Baltimore, Maryland); Elisabet Pujadas (Baltimore, Maryland) |
| ABSTRACT | The present disclosure provides computational methods for epigenetic analysis as well as systems for implementing such analyses. |
| FILED | Friday, June 16, 2017 |
| APPL NO | 16/310176 |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) Original (OR) Class G16B 20/20 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220076857 | SAFFMAN |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark SAFFMAN (Madison, Wisconsin) |
| ABSTRACT | A system and method for controlling particles using projected light are provided. In some aspects, the method includes generating a beam of light using an optical source, and directing the beam of light to a beam filter comprising a first mask, a first lens, a second mask, and a second lens. The method also includes forming an optical pattern using the beam filter, and projecting the optical pattern on a plurality of particles to control their locations in space. |
| FILED | Friday, January 03, 2020 |
| APPL NO | 17/420542 |
| CURRENT CPC | Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220077221 | Jain |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Faquir Chand Jain (Storrs, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Faquir Chand Jain (Storrs, Connecticut) |
| ABSTRACT | This invention includes quantum dot channel (QDC) Si FETs, which detect infrared radiation to serve as photodetectors. GeOx-cladded Ge quantum dots form the quantum dot channel. An assembly of cladded quantum dots, such as Ge and Si, with thin barrier layers (GeOx and SiOx) form a quantum dot superlattice (QDSL). A QDSL exhibits narrow energy widths of sub-bands (or mini-energy bands) with sub-bands separation ranging ˜0.2-0.5 eV. The energy separation depends on the barrier thickness (˜0.5-1 nm) and diameter of quantum dots (3-5 nm). Drain current magnitude in a QDSL layer or quantum dot channel depends on density of electrons in the QD inversion channel, which in turn depends on number of sub-bands participating in the conduction for a given drain voltage VD and gate voltage VG. Infrared photons with energy corresponding to the intra sub-band separation are absorbed as electrons in a lower sub-band make transition to the upper sub-band. |
| FILED | Friday, September 17, 2021 |
| APPL NO | 17/478363 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14652 (20130101) Original (OR) Class H01L 31/0384 (20130101) H01L 31/1136 (20130101) H01L 31/035218 (20130101) Pictorial Communication, e.g Television H04N 5/332 (20130101) H04N 5/378 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220077407 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Florida State University State Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhibin Yu (Tallahassee, Florida); Junqiang Li (Tallahassee, Florida); Xin Shan (Tallahassee, Florida) |
| ABSTRACT | An emissive perovskite ternary composite thin film comprising a perovskite material, an ionic-conducting polymer and an ionic-insulating polymer is provided. Additionally, a single-layer LEDs is described using a composite thin film of organometal halide perovskite (Pero), an ionic-conducting polymer (ICP) and an ionic-insulating polymer (IIP). The LEDs with Pero-ICP-IIP composite thin films exhibit a low turn-on voltage of about 1.9V (defined at 1 cd m−2 luminance) and a luminance of about 600,000 cd m−2. |
| FILED | Thursday, October 14, 2021 |
| APPL NO | 17/501704 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/004 (20130101) H01L 51/0077 (20130101) Original (OR) Class H01L 51/5032 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220077858 | Bhunia et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Swarup Bhunia (Gainesville, Florida); Christopher Vega (Gainesville, Florida); Shubhra Deb Paul (Gainesville, Florida) |
| ABSTRACT | Methods and systems are directed to creating a physical unclonable function (PUF) on a Field Programmable Gate Array (FPGA) and generating a unique signature for a device. The method includes, in part, designing a PUF by taking advantages of programmable logic elements on the FPGA, and extracting uninitialized values associated with one or more storage elements comprised in the PUF when the FPGA is powered up. The extracted uninitialized values can be combined to generate the unique signature for the device. The one or more storage elements can be bi-stable memory cells that are mapped to look up tables (LUTs) on the FPGA. The coordinates of these LUTs can be determined based on hamming distance analysis. Alternatively, the one or more storage elements can be memory cells associated with boundary scan cells of a boundary scan chain. |
| FILED | Friday, September 03, 2021 |
| APPL NO | 17/465958 |
| CURRENT CPC | Pulse Technique H03K 19/1737 (20130101) H03K 19/1776 (20130101) Original (OR) Class H03K 19/17728 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0866 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220077941 | Prothero et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Astrapi Corporation (Dallas, Texas) |
| ASSIGNEE(S) | Astrapi Corporation (Dallas, Texas) |
| INVENTOR(S) | Jerrold Prothero (Delray Beach, Florida); Tanay Bhatt (Richardson, Texas) |
| ABSTRACT | Systems, devices, software, and methods of the present invention enable frequency-based signal power analyses in software suitable for signal with either stationary and non-stationary spectrums. The methods that may be used throughout various systems including transmitters receivers, repeater, controllers, monitors, etc. and in software simulators to enable various signal power calculations and analyses, such as frequency spectrum analysis, throughout operating systems and that may be consistently applied in system design and operation simulations in a wide range of applications, such as interference and spectrum monitoring or clearance, object tracking, transmission channel and noise analyses, radiated power analysis, signal boundary interference, satellite downlink signal identification, pulsed radar monitoring, audio detection and identification, lidar systems, sonar systems, etc. |
| FILED | Thursday, November 18, 2021 |
| APPL NO | 17/530445 |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00503 (20130101) Transmission H04B 17/23 (20150115) Original (OR) Class H04B 17/26 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220078184 | TRAYNOR et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Patrick G. TRAYNOR (Gainesville, Florida); Christian PEETERS (Gainesville, Florida); Christopher PATTON (San Francisco, California); Imani SHERMAN (Cincinnati, Ohio); Daniel OLSZEWSKI (Gainesville, Florida); Thomas SHRIMPTON (Gainesville, Florida) |
| ABSTRACT | Various methods are provided for secure two-factor authentication, and more specifically, for incorporating a layer of security to two-factor authentication using Short Message Service in a manner virtually transparent to the end-user. Methods may include receiving a request for registration for two-factor authentication from a client including a username and password; providing a request for a mobile device number; receiving the mobile device number and a pre-shared key; sending to a mobile device an identity of the client and a server key share; receiving from the mobile device a mobile device key share; sending information corresponding to an exchange with the mobile device and a challenge derived from the pre-shared key to the client in response to the device key share corresponding to the server key share; receiving confirmation of registration with the mobile device; and establishing a shared key in response to verification of the confirmation. |
| FILED | Thursday, August 26, 2021 |
| APPL NO | 17/446023 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/166 (20130101) H04L 63/0435 (20130101) H04L 63/0838 (20130101) Original (OR) Class H04L 2463/082 (20130101) Wireless Communication Networks H04W 4/14 (20130101) H04W 12/069 (20210101) H04W 12/0431 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220078908 | Johnson, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alan T Johnson, Jr. (Philadelphia, Pennsylvania); Rajatesh R Gudibande (Philadelphia, Pennsylvania); Zhengqing John Qi (Albany, New York) |
| ABSTRACT | The present invention provides methods for fabricating graphene workpieces. The present invention also provides for products produced by the methods of the present invention and for apparatuses used to perform the methods of the present invention. |
| FILED | Thursday, March 25, 2021 |
| APPL NO | 17/212092 |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/32 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/1606 (20130101) H01L 29/78684 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/09 (20130101) Original (OR) Class H05K 1/0306 (20130101) H05K 3/06 (20130101) H05K 3/20 (20130101) H05K 3/125 (20130101) H05K 3/1216 (20130101) H05K 3/1275 (20130101) H05K 2201/0323 (20130101) H05K 2203/1338 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20220073217 | Iverson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brigham Young University (BYU) (Provo, Utah); University of Dayton Technology Partnerships Office (UDTPO) (Dayton, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brian D. Iverson (Provo, Utah); Rydge B. Mulford (Dayton, Ohio); Matthew R. Jones (Provo, Utah) |
| ABSTRACT | A method includes coupling a radiator panel assembly to a component, and conducting heat from the component via a thermally conductive hinge into at least one base radiator panel in the radiator panel assembly. The method further includes placing the at least one base radiator panel in a position to radiate a fraction of the heat into space through a surface of the at least one base radiator panel, and dynamically varying the position of the at least one base radiator panel to vary an amount of heat loss through the at least one base radiator panel to regulate a temperature of the component. |
| FILED | Friday, September 10, 2021 |
| APPL NO | 17/447358 |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/222 (20130101) B64G 1/503 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073433 | Doud et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Powdermet, Inc. (Euclid, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brian P. Doud (Cleveland Heights, Ohio); Mark V. Grogan (Cleveland, Ohio); Andrew Sherman (Mentor, Ohio) |
| ABSTRACT | A thermally-insulating composite material with co-shrinkage in the form of an insulating material formed by the inclusion of microballoons in a matrix material such that the microballoons and the matrix material exhibit co-shrinkage upon processing. The thermally-insulating composite material can be formed by a variety of microballoon-matrix material combinations such as polymer microballoons in a preceramic matrix material. The matrix materials generally contain fine rigid fillers. |
| FILED | Tuesday, June 08, 2021 |
| APPL NO | 17/341649 |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/58 (20130101) C04B 35/80 (20130101) C04B 35/515 (20130101) C04B 35/524 (20130101) C04B 35/571 (20130101) C04B 38/007 (20130101) Original (OR) Class C04B 38/08 (20130101) C04B 38/0645 (20130101) C04B 2111/28 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/32 (20130101) C08J 9/35 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 7/22 (20130101) C08K 7/24 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 59/028 (20130101) F16L 59/145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220074674 | ALEXANDER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ThermAvant Technologies, LLC (Columbia, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Benjamin ALEXANDER (Columbia, Missouri); Daniel POUNDS (Columbia, Missouri); Joshua SCHORP (St. Charles, Missouri); Bruce DROLEN (Altadena, California); Corey WILSON (San Francisco, California); Joseph BOSWELL (San Francisco, California) |
| ABSTRACT | A heat rejection panel that comprises a chassis having a first side, an opposing second side, and an aperture extending therethrough. The panel additionally comprises at least one oscillating heat pipe (OHP) plate disposed over a portion of the first side and/or the second side of the chassis. Each OHP plate includes a first face, an opposing second face, and a plurality of internal OHP channels. A portion of the first face and/or second face of each OHP plate is accessible for thermal interfacing with a heat source. A portion of the second face of each OHP plate is accessible for thermal interfacing with a heat sink. Each OHP plate will remove heat from the heat source, spread the removed heat throughout each OHP plate to provide an isothermal OHP plate, and reject the heat to the heat sink. |
| FILED | Tuesday, September 08, 2020 |
| APPL NO | 17/014681 |
| CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/04 (20130101) Original (OR) Class F28D 15/0208 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220075378 | Hewitt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert A Hewitt (Pasadena, California); Jacob Izraelevitz (Pasadena, California); Donald F Ruffatto (Pasadena, California); Luis Phillipe C.F. Tosi (Los Angeles, California); Matthew Gildner (Los Angeles, California); Gene B Merewether (Pasadena, California) |
| ABSTRACT | Systems and methods for visual inspection of a container such as an oil tank via a lighter-than-air aircraft are presented. According to one aspect, the aircraft includes a gondola attached to a balloon filled with lighter-than-air gas. Rigidly attached to the gondola is a suite of sensors, including a camera sensor, an inertial measurement unit and a range sensor. Navigation of the aircraft is based on information sensed by the suite of sensors and processed by control electronics arranged in the gondola. Embedded in the control electronics is an extended Kalman filter that calculates pose estimates of the aircraft based on the information sensed by the inertial measurement unit and updated by the camera sensor. The extended Kalman filter uses the information sensed by the range sensor to reduce uncertainty in the calculated pose estimate. Images captured by the camera sensor can be used to evaluate state of the container. |
| FILED | Monday, June 21, 2021 |
| APPL NO | 17/352798 |
| CURRENT CPC | Lighter-than Air Aircraft B64B 1/22 (20130101) B64B 1/36 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/954 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0094 (20130101) Original (OR) Class G05D 1/101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220076855 | Thomsen, III et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Donald L. Thomsen, III (Yorktown, Virginia); William Girard (Newport News, Virginia) |
| ABSTRACT | A radiation shielded vault structure includes a rigid outer structure comprising a plurality of rigid structural components that are interconnected at elongated joints to define an interior space. The structural components include a layer of lower atomic number (Z) material such as aluminum alloy and one or more layers of higher atomic number (Z) material titanium and/or tantalum. The vault structure may include radiation shield members extending along the elongated joints to provide radiation shielding at the elongated joints. The shield members comprise a higher atomic number (Z) material such as titanium or tantalum. The rigid structural components may comprise plate members that are interconnected along side edges thereof. End plates may be attached to the plate members to close off the interior space. |
| FILED | Tuesday, June 22, 2021 |
| APPL NO | 17/354597 |
| CURRENT CPC | Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 1/085 (20130101) Original (OR) Class G21F 1/125 (20130101) G21F 7/00 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 20/00 (20130101) H02S 30/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220077371 | Howe et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HOWE INDUSTRIES LLC (Scottsdale, Arizona) |
| ASSIGNEE(S) | HOWE INDUSTRIES LLC (Scottsdale, Arizona) |
| INVENTOR(S) | Troy Michael Howe (Tempe, Arizona); Steven Daniel Howe (Mesa, Arizona) |
| ABSTRACT | A thermoelectric converter including a thermoelectric generator and a radiation source. The thermoelectric generator includes a hot source, a cold source, n-type material, and p-type material. The radiation source emits ionizing radiation that increases electrical conductivity. Also detailed is a method of using radiation to reach high efficiency with a thermoelectric converter that includes providing a thermoelectric generator and a radiation source, with the thermoelectric generator including a hot source, a cold source, n-type material, and p-type material, and emitting ionizing radiation with the radiation source to increase the electrical conductivity which strips electrons in the n-type material, the p-type material, or both the n-type material and p-type material from their nuclei with the electrons then free to move within the material. |
| FILED | Wednesday, March 10, 2021 |
| APPL NO | 17/198040 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/30 (20130101) Original (OR) Class H01L 35/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20220072122 | Verardi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paulo H. Verardi (Mansfield, Connecticut); Brittany Jasperse (Brick, New Jersey); Caitlin M. O'Connell (Glastonbury, Connecticut); Yuxiang Wang (Storrs, Connecticut) |
| ABSTRACT | Disclosed herein are methods for the rapid generation of recombinant viruses, for example, to enable vaccine development. |
| FILED | Thursday, July 01, 2021 |
| APPL NO | 17/365746 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/275 (20130101) Original (OR) Class A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 2710/24034 (20130101) C12N 2710/24041 (20130101) C12N 2710/24051 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073953 | PONCIANO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | GRISEL P. PONCIANO (CASTRO VALLEY, California); COLLEEN M. MCMAHAN (SAUSALITO, California); PAUL HOEPRICH (SACRAMENTO, California); PATRICK SCANNON (SAN FRANCISCO, California) |
| ABSTRACT | Disclosed herein are recombinant enzymes derived from various rubber-producing plants and the use of those enzymes in the production of natural rubber outside of plant tissues. Systems and methods for the utilization of these enzymes in the production of natural rubber are also provided. |
| FILED | Wednesday, September 08, 2021 |
| APPL NO | 17/469744 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1085 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 5/026 (20130101) Original (OR) Class Enzymes C12Y 205/0102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073999 | He |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Kansas (Lawrence, Kansas); Kansas State University Research Foundation (Manhattan, Kansas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mei He (Gainesville, Florida) |
| ABSTRACT | Methods for producing engineered exosomes and other vesicle-like biological targets, including allowing a target vesicle-like structure to react and bind with immunomagnetic particles; capturing the immunomagnetic particle/vesicle complex by applying a magnetic field; further engineering the captured vesicles by surface modifying with additional active moieties or internally loading with active agents; and releasing the engineered vesicle-like structures, such as by photolytically cleaving a linkage between the particle and engineered vesicle-like structures, thereby releasing intact vesicle-like structures which can act as delivery vehicles for therapeutic treatments. |
| FILED | Friday, October 29, 2021 |
| APPL NO | 17/514724 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6901 (20170801) A61K 49/0097 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 3/502761 (20130101) Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 1/015 (20130101) B03C 1/30 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/5434 (20130101) G01N 33/54333 (20130101) G01N 2446/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 20220072262 | Jacobs et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Bryson Jacobs (Quaker Hill, Connecticut); Savannah Lyle (Saint Petersburg, Florida) |
| ABSTRACT | In an example, a ventilator includes an outer container containing liquid, an inverted container submerged in the liquid to provide inverted container space between a closed top and an inner container liquid level; gas supply line to supply breathing gas to the inverted container space; and inhalation line having an inlet in the inverted container space to provide breathing gas to patient. The inverted container moves upward from a first elevation when the inverted container space reaches a hydrostatic delivery pressure and volume of the inverted container space increases. The inverted container stops moving upward and the gas supply line stops supplying when the inverted container reaches a second elevation above the first. Based on a breath demand signal or preset timing, the inhalation line opens to permit flow of breathing gas to the patient at the hydrostatic delivery pressure, lowering the inverted container due to lost buoyancy resulting in sinkage. |
| FILED | Tuesday, November 16, 2021 |
| APPL NO | 17/527904 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/0003 (20140204) A61M 16/16 (20130101) Original (OR) Class A61M 16/208 (20130101) A61M 2205/3348 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220074912 | Deline |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | James E. Deline (Egg Harbor City, New Jersey) |
| ABSTRACT | Various embodiments of the present invention are directed towards a system and method to dispense an explosive compound onto a substrate. An example device includes a solvent having the explosive compound dissolved in the solvent to form a sample. A delivery mechanism dispenses the sample in a dispersed manner to sufficiently vaporize the solvent to prevent wicking while dispersing a residue of the explosive compound on the substrate to enable detection by explosive detection tools. |
| FILED | Wednesday, June 23, 2021 |
| APPL NO | 17/355943 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/38 (20130101) G01N 1/2813 (20130101) G01N 33/227 (20130101) Original (OR) Class G01N 2001/2893 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220076262 | Boyd et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Daniel A. Boyd (Arlington, Virginia); Kelli L. Biegger (McLean, Virginia); Chang Ellison (Arlington, Virginia); Jason Lim (Alexandria, Virginia) |
| ABSTRACT | A method for verifying an identity of an individual as a first party via a first party system by a second party system comprises: sending a request for identification information of the first party; receiving first party information associated with a mobile identification credential (MIC) which the first party system received from an authorizing party system (APS) before the second party system sends the request for identification information of the first party to the first party system, the first party having consented to release the first party information to the second party system, and the first party information having been verified by the APS before the APS sends the MIC to the first party system; using the verified first party information associated with the MIC to verify or not verify an identity of the first party; verifying the identity of the first party before providing services to the first party. |
| FILED | Friday, November 19, 2021 |
| APPL NO | 17/531194 |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 20/065 (20130101) G06Q 20/409 (20130101) G06Q 20/3827 (20130101) G06Q 20/4014 (20130101) Original (OR) Class G06Q 20/38215 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20220071494 | Celinski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Zbigniew Celinski (Colorado Springs, Colorado); Janusz Hankiewicz (Colorado Springs, Colorado); Robert Camley (Colorado Springs, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zbigniew Celinski (Colorado Springs, Colorado); Janusz Hankiewicz (Colorado Springs, Colorado); Robert Camley (Colorado Springs, Colorado) |
| ABSTRACT | Provided are a system and a method for determining the temperature of a body by imaging a hydrogen proton-rich material positioned within the body using nuclear magnetic resonance imaging. A method to increase changes in the MRI signal strength as a function of temperature, thus improving temperature sensitivity, is also provided. The system and method employ polymers having mechanical stability and magnetic image brightness at low temperatures of between 0° C. and −65° C. or high temperatures of between +37° C. and +80° C. |
| FILED | Wednesday, September 08, 2021 |
| APPL NO | 17/469726 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/015 (20130101) Original (OR) Class A61B 5/055 (20130101) A61B 18/0218 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 41/0052 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220073433 | Doud et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Powdermet, Inc. (Euclid, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brian P. Doud (Cleveland Heights, Ohio); Mark V. Grogan (Cleveland, Ohio); Andrew Sherman (Mentor, Ohio) |
| ABSTRACT | A thermally-insulating composite material with co-shrinkage in the form of an insulating material formed by the inclusion of microballoons in a matrix material such that the microballoons and the matrix material exhibit co-shrinkage upon processing. The thermally-insulating composite material can be formed by a variety of microballoon-matrix material combinations such as polymer microballoons in a preceramic matrix material. The matrix materials generally contain fine rigid fillers. |
| FILED | Tuesday, June 08, 2021 |
| APPL NO | 17/341649 |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/58 (20130101) C04B 35/80 (20130101) C04B 35/515 (20130101) C04B 35/524 (20130101) C04B 35/571 (20130101) C04B 38/007 (20130101) Original (OR) Class C04B 38/08 (20130101) C04B 38/0645 (20130101) C04B 2111/28 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/32 (20130101) C08J 9/35 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 7/22 (20130101) C08K 7/24 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 59/028 (20130101) F16L 59/145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 20220072685 | Reimers |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PCCI, Inc. (Alexandria, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen Reimers (Falls Church, Virginia) |
| ABSTRACT | The present invention is generally directed towards clamps for high tension load applications. In particular, the invention relates to high holding power clamps in which fabric can be secured, and which can withstand a large amount of force, including, in at least some embodiments, the maximum amount of tension permitted in various modern high strength fabrics and/or fiber weaves. In at least one embodiment, a holding clamp has a single-V design, with at least three areas that exert pinching effects on fabric held in the clamp, and at least four capstan areas that exert capstan effects on the clamped fabric. In at least a further embodiment, a holding clamp has a double-V design, with at least six areas that exert pinching effects on fabric held in the clamp, and at least seven capstan areas that exert capstan effects on the clamped fabric. |
| FILED | Friday, September 03, 2021 |
| APPL NO | 17/466853 |
| CURRENT CPC | Tools or Bench Devices Not Otherwise Provided For, for Fastening, Connecting, Disengaging or Holding B25B 5/02 (20130101) B25B 5/14 (20130101) B25B 5/163 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 20220074420 | Miller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kyle Louis Miller (Cincinnati, Ohio); Andrew Breeze-Stringfellow (Montgomery, Ohio) |
| ABSTRACT | A turbo machine, a computer-implemented method, and a computer system for operating a compressor assembly are provided. The method includes comparing a first data set and a second data set to determine a first correlation factor, comparing the first correlation factor to a first threshold that at least partially determines whether a stall precursor exists, removing mean values from the first data set and the second data set, comparing the first data set and the second data set each removed of mean values to determine a second correlation factor, and comparing the second correlation factor to the first threshold, and classifying the stall precursor as either a spike stall precursor, a modal stall precursor, or a combination stall precursor. |
| FILED | Wednesday, September 09, 2020 |
| APPL NO | 17/015400 |
| CURRENT CPC | Non-positive-displacement Pumps F04D 27/001 (20130101) Original (OR) Class F04D 27/02 (20130101) Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G F05B 2220/302 (20130101) F05B 2270/301 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2270/101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20220076591 | Ratcliffe et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alan Bao-Chan Dang (, None); United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark B. Ratcliffe (Piedmont, California); Liang Ge (Foster City, California); Alan Bao-Chan Dang (Orange, California) |
| ABSTRACT | A method and system are presented for performing virtual surgery simulations. The computer system includes a processor and a memory. The method includes receiving user input from a user via a user interface. The user input includes input representing surgical operations or non-surgical invasive procedures. The method also includes processing the user input and utilizing the input to generate or modify a computational model. The method also includes running simulations using the computational model in accordance with the user input. After running the simulations, the method further includes determining results from the simulations. The results correspond to probable effects or outcomes of performing real life surgical operations or non-surgical invasive procedures corresponding to the user input. Last, the method includes presenting the results to the user via the user interface. |
| FILED | Tuesday, May 04, 2021 |
| APPL NO | 17/307719 |
| CURRENT CPC | Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 5/00 (20130101) G09B 9/00 (20130101) G09B 23/28 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Reconnaissance Office (NRO)
| US 20220073356 | Wagner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The George Washington University (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael J. Wagner (Rockville, Maryland); Nathan A. Banek (Rockville, Maryland) |
| ABSTRACT | The present disclosure relates to an improved process for the synthesis of hydrogen terminated silicon from Zintl phases. The hydrogen terminated silicon is useful, for example, as explosives, chemical and biochemical sensors, optoelectronic materials and Li-ion battery anode ion storage materials. The present disclosure also relates to an improved process for the synthesis of nanomaterials and composites from Zintl phases. The nanomaterials and composites are useful, for example, as ion storage materials. |
| FILED | Thursday, September 09, 2021 |
| APPL NO | 17/470621 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 33/021 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/82 (20130101) C01P 2004/04 (20130101) C01P 2006/12 (20130101) C01P 2006/16 (20130101) C01P 2006/40 (20130101) Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 43/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/58 (20130101) H01M 10/0525 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 20220077656 | LIANG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HEWLETT PACKARD ENTERPRISE DEVELOPMENT LP (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | DI LIANG (Santa Barbara, California); CHIH C. SHIH (San Jose, California); KEVIN B. LEIGH (Houston, Texas); GEZA KURCZVEIL (Santa Barbara, California); MARCO FIORENTINO (Milpitas, California) |
| ABSTRACT | Techniques and systems for a semiconductor laser, namely a grating-coupled surface-emitting (GCSE) comb laser, having thermal management for facilitating dissipation of heat, integrated thereon. The thermal management is structured in manner that prevents deformation or damage to the GCSE laser chips included in the semiconductor laser implementation. The disclosed thermal management elements integrated in the laser can include: heat sinks; support bars; solder joints; thermal interface material (TIM); silicon vias (TSV); and terminal conductive sheets. Support bars, for example, having the GCSE laser chip positioned between the bars and having a height that is higher than a thickness of the GCSE laser chip. Accordingly, the heat sink can be placed on top of the support bars such that heat is dissipated from the GCSE laser chip, and the heat sink is separated from directed contact with the GCSE laser chip due to the height of the support bars. |
| FILED | Tuesday, September 08, 2020 |
| APPL NO | 17/015001 |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/024 (20130101) H01S 5/105 (20130101) H01S 5/18386 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 20220073883 | Andersen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Peter Andersen (Baltimore, Maryland); Chulan Kwon (Ellicott City, Maryland) |
| ABSTRACT | The present invention relates to compositions and methods for producing, identifying and isolating heart progenitor cells. |
| FILED | Thursday, July 25, 2019 |
| APPL NO | 17/263142 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) A61K 35/34 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0657 (20130101) Original (OR) Class C12N 5/0696 (20130101) C12N 2501/15 (20130101) C12N 2501/16 (20130101) C12N 2501/21 (20130101) C12N 2501/155 (20130101) C12N 2501/415 (20130101) C12N 2506/45 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 20220074348 | Johnson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher Ryan Johnson (Fairfield, Ohio); Paul Hadley Vitt (Liberty Twp, Ohio); Eric Joseph Schroeder (Loveland, Ohio); Carlos Gilberto Fernandez-Soto (Fairfield Twp, Ohio) |
| ABSTRACT | Aspects of the disclosure generally relate to a turbine engine and method of operating a turbine engine having an engine core including a compressor, combustor, and turbine in axial flow arrangement, whereby a working airflow passes through the engine core from the compressor to the turbine to define a flow direction through the engine core. The method includes generating a shockwave in the working airflow that propagates in the flow direction, and at least partially attenuating the shockwave. |
| FILED | Thursday, September 10, 2020 |
| APPL NO | 17/016670 |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/24 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, March 10, 2022.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/details-patents-20220310.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page