FedInvent™ Patent Applications
Application Details for Thursday, June 02, 2022
This page was updated on Friday, June 03, 2022 at 06:08 PM GMT
Department of Health and Human Services (HHS)
| US 20220167907 | Donahue |
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| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | John Kevin Donahue (Hopkinton, Massachusetts) |
| ABSTRACT | In some aspects, the disclosure relates methods for identifying ventricular tachycardia in subjects, e.g., subjects who have previously experienced a myocardial infarction. In some embodiments, methods of the disclosure comprise measuring action potential durations and/or expression levels of KCNE3 and/or KCNE4 in a subject. In some aspects, the disclosure relates to methods and compositions for reducing or inhibiting the activity of KCNE3 and/or KCNE4, for example, in subjects having ventricular tachycardia. |
| FILED | Thursday, April 02, 2020 |
| APPL NO | 17/600271 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/363 (20210101) Original (OR) Class A61B 5/367 (20210101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2320/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220167918 | Howard et al. |
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| FUNDED BY |
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| APPLICANT(S) | GEORGE MASON RESEARCH FOUNDATION, INC. (Fairfax, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Marissa A. Howard (Richmond, Virginia); Lance A. Liotta (Bethesda, Maryland); Rachel Naidich (Fairfax, Virginia); Matthew Luu Trang (Nokesville, Virginia); Ish Sethi (Chantilly, Virginia); Rebecca Woodhouse (Oakton, Virginia); Kshamata Neupane (Haymarket, Virginia) |
| ABSTRACT | A wearable device measures, tracks, and monitors a wearer's physical physiological conditions during a rehabilitation period. Metrics such as temperature, patellar shifting, limb circumference, and acceleration may be collected. Changes in monitored conditions may be assessed for detecting medical abnormalities which require specialized attention, including for example embolisms or infections. A networked communication system and various user interfaces may be used for medical support personnel and patients alike to stay updated with the patient's rehabilitation progress and to make adjustments in a patient's individual rehabilitation program. |
| FILED | Friday, February 18, 2022 |
| APPL NO | 17/651661 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/015 (20130101) A61B 5/0024 (20130101) A61B 5/0048 (20130101) A61B 5/0053 (20130101) A61B 5/112 (20130101) A61B 5/746 (20130101) A61B 5/1107 (20130101) A61B 5/1114 (20130101) A61B 5/1126 (20130101) A61B 5/4519 (20130101) A61B 5/4528 (20130101) A61B 5/4585 (20130101) A61B 5/4848 (20130101) A61B 5/6824 (20130101) A61B 5/6828 (20130101) Original (OR) Class A61B 5/6829 (20130101) A61B 5/7275 (20130101) A61B 5/7465 (20130101) A61B 2503/08 (20130101) A61B 2503/10 (20130101) A61B 2505/09 (20130101) A61B 2562/0219 (20130101) A61B 2562/0247 (20130101) A61B 2562/0261 (20130101) A61B 2562/0271 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 2230/08 (20130101) A61H 2230/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168230 | Zhou et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jiangbing Zhou (Cheshire, Connecticut); Kevin Sheth (Madison, Connecticut); Gang Deng (Hubei, China PRC); Shenqi Zhang (New Haven, Connecticut); Zeming Chen (New Haven, Connecticut); Chao Ma (Beijing, China PRC) |
| ABSTRACT | At least five classes of MNP-based compounds have been demonstrated to form supramolecular particles for effective delivery by injection or topically of different types of therapeutic, prophylactic, or diagnostic agents. These compounds are isolated from natural sources such as plants. Exemplary MNP-based compounds, from which synthetic analogs or derivatives are made and appreciated to function similarly, e.g., capable of forming supramolecular particles include diterpene resin acids (e.g., abietic acid and pimaric acid), phytosterols (e.g., stigmasterol and β-sitosterol), lupane-type pentacyclic triterpenes (e.g., lupeol and betulinic acid), oleanane-type pentacyclic tritepenes (e.g., glycyrrhetic acid and sumaresinolic acid), and lanostane-type triterpenes and derivatives (e.g., dehydrotrametenolic acid and poricoic acid A). In some cases the MNP-based compounds are therapeutically effective in the absence of added therapeutic, prophylactic or diagnostic agent. Betulinic acid (BA) NPs were capable of efficiently penetrating ischemic brains and effectively promoting functional recovery as antioxidant agents. |
| FILED | Wednesday, February 26, 2020 |
| APPL NO | 17/434297 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5123 (20130101) Original (OR) Class A61K 31/64 (20130101) A61K 31/137 (20130101) A61K 31/343 (20130101) A61K 31/519 (20130101) A61K 47/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168231 | Xu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
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| INVENTOR(S) | Qiaobing Xu (Lexington, Massachusetts); Ming Wang (Beijing, China PRC) |
| ABSTRACT | Provided are methods of treating a human lipoprotein metabolism disorder or a cardiovascular disease, comprising administering to a subject in need thereof a lipidoid nanoparticle, comprising a lipid, a CRISPR/Cas9 mRNA, and a single guide RNA (sgRNA) |
| FILED | Monday, December 06, 2021 |
| APPL NO | 17/543173 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5123 (20130101) Original (OR) Class A61K 31/7088 (20130101) A61K 38/465 (20130101) A61K 48/0041 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/06 (20180101) A61P 9/00 (20180101) Acyclic or Carbocyclic Compounds C07C 323/12 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 2310/20 (20170501) C12N 2320/32 (20130101) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168269 | Kumar et al. |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (CLEVELAND, Ohio) |
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| INVENTOR(S) | Alagramam N. Kumar (Cleveland, Ohio); Suhasini Gopal Ramanujam (Cleveland, Ohio) |
| ABSTRACT | A method of treating a glycosylation-defective protein associated disease or disorder in a subject, the method includes administering to the subject a therapeutically effective amount of a Sarco/ER ATPase (SERCA) inhibitor. |
| FILED | Tuesday, September 07, 2021 |
| APPL NO | 17/468274 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/343 (20130101) A61K 31/357 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/16 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168270 | Choate et al. |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
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| INVENTOR(S) | Keith Choate (New Haven, Connecticut); Lihi Atzmony (New Haven, Connecticut) |
| ABSTRACT | The present invention relates to compositions comprising at least one lipid-lowering drug or a derivative thereof for the treatment of skin diseases or disorders. In various aspects of the invention, the composition further comprises at least one lipid or a derivative thereof. |
| FILED | Wednesday, June 10, 2020 |
| APPL NO | 17/618215 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 31/366 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/12 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168300 | Yoon et al. |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
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| INVENTOR(S) | Young-sup Yoon (Atlanta, Georgia); Ji Woong Han (Decatur, Georgia); Hyunsuk Shim (Atlanta, Georgia) |
| ABSTRACT | This disclosure relates to managing diabetic neuropathy using compounds disclosed herein. In certain embodiments, this disclosure relates to methods of treating or preventing vascular conditions such as diabetic neuropathy comprising administering a compound capable of epigenetic modification, such as histone deacetylase inhibitors, to a subject in need thereof. In certain embodiments, this disclosure relates to the use of HDAC inhibitors to treat directly diabetic neuropathies and pain without the use of progenitor cells or stem cells. In certain embodiments, the subject is at risk of, exhibiting symptoms of, or diagnoses with diabetes, diabetic neuropathy, peripheral neuropathy, autonomic neuropathy, radiculoplexus neuropathy, mononeuropathy, diabetic retinopathy, or complications related thereto. In certain embodiments, the compound is selected from belinostat, quisinostat, and vorinostat. |
| FILED | Wednesday, February 12, 2020 |
| APPL NO | 17/430624 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/167 (20130101) A61K 31/506 (20130101) Original (OR) Class A61K 35/12 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) A61P 25/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168325 | NELSON et al. |
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| APPLICANT(S) | THE UNIVERSITY OF VERMONT (Burlington, Vermont) |
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| INVENTOR(S) | Mark T. NELSON (Burlington, Vermont); Fabrice DABERTRAND (Hinesburg, Vermont); Osama F. HARRAZ (Burlington, Vermont); Masayo KOIDE (Richmond,, Vermont) |
| ABSTRACT | The present application relates to methods for treating conditions characterized by reduced cerebral blood flow that include selecting a subject having a condition characterized by reduced cerebral blood flow. A therapeutic agent that increases the levels of PIP2 is administered under conditions effective to treat the condition in the subject. Also disclosed are methods for treating CADASIL as well as methods for restoring cerebral blood flow and functional hyperemia. |
| FILED | Friday, March 20, 2020 |
| APPL NO | 17/598008 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/685 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168328 | Capaldi et al. |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
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| INVENTOR(S) | Andrew P. Capaldi (Tucson, Arizona); James E. Hughes Hallett (Tucson, Arizona) |
| ABSTRACT | Methods and compositions for activating TORC1 aggregate formation in a fungi or a parasite, wherein TORC1 aggregate formation inhibits growth of the fungi or parasite. TORC1 aggregate formation may be activated using small molecules or other agents, and said agents may be used to treat or prevent a disease or condition associated with the fungi and parasite. The agent may target Kog1 of TORC1, e.g., the agent may directly or indirectly inhibit Kog1 leading to aggregation of the TORC1 complex. |
| FILED | Monday, February 14, 2022 |
| APPL NO | 17/671106 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/60 (20130101) A61K 31/155 (20130101) A61K 31/7056 (20130101) Original (OR) Class A61K 39/3955 (20130101) A61K 45/06 (20130101) Peptides C07K 16/18 (20130101) C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2500/10 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168329 | ADLI |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
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| INVENTOR(S) | Mazhar ADLI (Chicago, Illinois) |
| ABSTRACT | Described herein are methods for inhibiting protein arginine methyltransferase activity to create conditional vulnerability in tumors, thereby enhancing the effects of DNA damaging agents, methods of inhibiting tumor growth and/or reducing the volume of tumors using the same, and pharmaceutical compositions useful for carrying out the disclosed methods. In a further aspect, the methods and compositions disclosed herein exhibit synthetic lethality to tumor cells but produce few side effects. |
| FILED | Friday, March 27, 2020 |
| APPL NO | 17/441984 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) A61K 31/7068 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168340 | Spiller et al. |
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| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Kara L. Spiller (Glenside, Pennsylvania); Kathryn L. Wofford (Philadelphia, Pennsylvania) |
| ABSTRACT | In one aspect, the invention provides a composition comprising at least one monocyte comprising an agent that increases monocyte homing to a site of injury, and an effective amount of a drug. In another aspect, the invention provides a method of using the composition to deliver a drug to a site of injury. |
| FILED | Friday, February 18, 2022 |
| APPL NO | 17/651673 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1647 (20130101) A61K 31/573 (20130101) A61K 35/15 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168353 | MOSKOWITZ et al. |
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| APPLICANT(S) | CELLPHIRE INC. (Rockville, Maryland) |
| ASSIGNEE(S) | CELLPHIRE INC. (Rockville, Maryland) |
| INVENTOR(S) | Keith Andrew MOSKOWITZ (Westfield, Indiana); Braden Carl ISHLER (Gaithersburg, Maryland); William Matthew DICKERSON (Washington, District of Columbia); Narendra Nath TANDON (Gaithersburg, Maryland); Amber Nicole LEE (Rockville, Maryland); Stephon Edward AMOS (Buckeystown, Maryland); Rafael JORDA (Merignac, France); Michael Alexander MATTHEWS (Arlington, Virginia) |
| ABSTRACT | In some embodiments provided herein is a method of treating a coagulopathy in a subject that is being administered or has been administered an antiplatelet agent, the method comprising: (a) determining that the subject has an abnormal result for evaluation of one or more clotting parameters; and (b) after (a), administering to the subject in need thereof an effective amount of a composition comprising platelets or platelet derivatives and an incubating agent comprising one or more salts, a buffer, optionally a cryoprotectant, and optionally an organic solvent. |
| FILED | Wednesday, February 16, 2022 |
| APPL NO | 17/673773 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0221 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/19 (20130101) Original (OR) Class A61K 38/363 (20130101) A61K 45/06 (20130101) A61K 47/02 (20130101) A61K 47/26 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/04 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0644 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/86 (20130101) G01N 33/96 (20130101) G01N 33/6893 (20130101) G01N 2333/705 (20130101) G01N 2800/224 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168359 | Peltz et al. |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
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| INVENTOR(S) | Gary Peltz (Redwood City, California); Dan Xu (Fremont, California) |
| ABSTRACT | Methods are provided for producing a population of hepatocyte-like cells (iHeps) from a population of adipocyte-derived stem cells (ASCs). Aspects of the methods include placing a population of ASCs into a three dimensional culture (e.g., hanging drop suspension culture, high density culture, spinner flask culture, microcarrier culture, etc.), and contacting the cells with a first and second culture medium. Also provided are methods of treating an individual, which include producing a population of iHeps from a population of ASCs, and administering an effective number of iHeps into the individual. Kits for practicing the methods are also described herein. |
| FILED | Tuesday, February 15, 2022 |
| APPL NO | 17/672528 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/407 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/067 (20130101) C12N 5/0696 (20130101) C12N 2500/62 (20130101) C12N 2501/12 (20130101) C12N 2501/16 (20130101) C12N 2501/39 (20130101) C12N 2501/119 (20130101) C12N 2501/155 (20130101) C12N 2501/237 (20130101) C12N 2501/415 (20130101) C12N 2501/602 (20130101) C12N 2501/603 (20130101) C12N 2501/604 (20130101) C12N 2501/606 (20130101) C12N 2506/45 (20130101) C12N 2506/1384 (20130101) C12N 2510/00 (20130101) C12N 2513/00 (20130101) C12N 2533/90 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168364 | HANG et al. |
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| APPLICANT(S) | THE ROCKEFELLER UNIVERSITY (NEW YORK, New York) |
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| INVENTOR(S) | HOWARD HANG (DEL MAR, California); MATTHEW GRIFFIN (NEW YORK, New York) |
| ABSTRACT | Provided are compositions and methods based in part on the discovery that Enterococcus faecium secreted antigen A (SagA)-expressing bacteria are protective against enteric infections and enhances immune checkpoint inhibitor efficacy against cancer. Bacteria that express SagA or heterologous SagA, or orthologs thereof, are provided, and are included as nutraceutical, pharmaceutical, and probiotic formulations, as well as components of food products, including dairy products. |
| FILED | Thursday, February 20, 2020 |
| APPL NO | 17/432500 |
| CURRENT CPC | Dairy Products, e.g Milk, Butter, Cheese; Milk or Cheese Substitutes; Making Thereof A23C 9/1234 (20130101) Fodder A23K 10/18 (20160501) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/135 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) Indexing Scheme Relating to Lactic or Propionic Acid Bacteria Used in Foodstuffs or Food Preparation A23Y 2220/49 (20130101) A23Y 2220/67 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/747 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/315 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168372 | LONGO et al. |
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| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
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| INVENTOR(S) | Valter D. LONGO (Playa del Rey, California); Roberta BUONO (Newport Beach, California) |
| ABSTRACT | A method for treating leukemia and in particular, lymphoblastic leukemia is provided. The method includes a step of administering an FMD to a subject identified as having leukemia optionally in combination with a chemotherapeutic agent and/or an autophagy inhibitor. |
| FILED | Wednesday, December 01, 2021 |
| APPL NO | 17/539726 |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/17 (20160801) A23L 33/30 (20160801) A23L 33/115 (20160801) Preparations for Medical, Dental, or Toilet Purposes A61K 31/155 (20130101) A61K 31/436 (20130101) A61K 31/573 (20130101) A61K 31/4706 (20130101) A61K 36/185 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168379 | Remaley et al. |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Alan T. Remaley (Bethesda, Maryland); Scott M. Gordon (Lexington, Kentucky) |
| ABSTRACT | Described herein is the design and construction of a class of lipoprotein targeting protease inhibitors. Small peptides with protease inhibitor activity are conjugated to hydrophobic, lipoprotein targeting molecules using, for instance, amine reactive chemistry. Methods of use of the resultant lipoprotein targeting protease inhibitor (antiprotease) molecules are also described. Also described is the production and use of protease inhibitor enriched HDL particles, as well as A1AT-peptide-enriched HDL particles, and their use in various therapeutic contexts. |
| FILED | Wednesday, February 16, 2022 |
| APPL NO | 17/673361 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/005 (20130101) Original (OR) Class A61K 38/07 (20130101) A61K 38/08 (20130101) A61K 38/10 (20130101) A61K 38/58 (20130101) A61K 38/1767 (20130101) A61K 47/60 (20170801) A61K 47/545 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168390 | Huttenlocher et al. |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anna Huttenlocher (Madison, Wisconsin); Deane Mosher (Madison, Wisconsin); Valeriu Bortnov (Madison, Wisconsin); David Bennin (Madison, Wisconsin) |
| ABSTRACT | A method to inhibit neutrophil recruitment to damaged tissue, thereby inhibiting inflammation in a subject. The method includes administering to an anti-inflammatory amount of a myeloid-derived growth factor (“MYDGF”). Also disclosed are corresponding pharmaceutical compositions of matter containing the MYDGF. |
| FILED | Wednesday, September 22, 2021 |
| APPL NO | 17/481490 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/18 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168392 | Eichenbaum et al. |
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| FUNDED BY |
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| APPLICANT(S) | Janssen Pharmaceutica NV (Beerse, Belgium) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gary Eichenbaum (Belle Mead, New Jersey); Sanchita Ghosh (North Potomac, Maryland); Alfred Tonelli (Upper Nyack, New York) |
| ABSTRACT | Methods of mitigating vascular injury, promoting organ and hematopoietic recovery, accelerating vascular recovery, and enhancing survival in a subject treated with radiation therapy or chemotherapy are described. In particular, an effective amount of a thrombopoietin (TPO) mimetic, such as RWJ-800088, is used at the appropriate times relative to the Total Body Irradiation or Chemotherapy exposure to achieve these prophylactic and/or therapeutic benefits. |
| FILED | Friday, February 18, 2022 |
| APPL NO | 17/651675 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/196 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 47/60 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 39/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168402 | Cantley et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lewis C. Cantley (Cambridge, Massachusetts); Marcia Noreen Paddock (New York, New York); Diana Grace Wang (New York, New York) |
| ABSTRACT | As described herein, phosphatidylinositol-5-phosphate 4-kinases (PIP4Ks) have an allosteric function in addition to their catalytic activity. The allosteric function suppresses PIP5K-mediated PI(4,5)P2 synthesis and insulin-dependent conversion to PI(3,4,5)P3. Further described herein are methods for treatment of diabetes, metabolic syndrome, insulin resistance, a obesity, cancer, immune deficiency, autoimmune disease, infection, or a combination thereof. |
| FILED | Friday, April 10, 2020 |
| APPL NO | 17/602540 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 31/713 (20130101) A61K 38/45 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) A61P 37/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1205 (20130101) Enzymes C12Y 207/01149 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168414 | Cohen et al. |
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| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexander A. Cohen (Pasadena, California); Pamela J. Bjorkman (Altadena, California) |
| ABSTRACT | Disclosed herein include multivalent carriers comprising a plurality of heterologous coronavirus proteins antigens derived from different coronaviruses. The multivalent carriers herein described can elicit heterologous binding and neutralization properties against coronoviruses that differ from the coronoviruses from which the coronavirus antigens are derived to produce the multivalent carriers. Also provided herein include vaccine compositions comprising the multivalent carriers and related methods using the vaccine compositions in various therapeutic and prophylactic applications. |
| FILED | Wednesday, November 10, 2021 |
| APPL NO | 17/523813 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) A61K 39/215 (20130101) Original (OR) Class A61K 39/385 (20130101) A61K 2039/55555 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) A61P 37/04 (20180101) Peptides C07K 14/165 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2770/20022 (20130101) C12N 2770/20034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168426 | MEJIA ONETO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | TAMBO, INC. (San Francisco, California); THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jose Manuel MEJIA ONETO (San Francisco, California); Nathan YEE (San Francisco, California); Maksim ROYZEN (San Francisco, California); Sangeetha SRINIVASAN (San Francisco, California); Ethan MILLER (San Francisco, California) |
| ABSTRACT | Cyclooctene conjugates of therapeutic or diagnostic agents have improved aqueous solubility and can release the agents upon contact with a tetrazine-containing biomaterial. The cyclooctene conjugates provide site-selective delivery of agents at the location of the tetrazine-containing biomaterial in a subject. The compositions and methods have applications in the treatment of various diseases or conditions including cancer, tumor growths, and bacterial infections. |
| FILED | Tuesday, December 14, 2021 |
| APPL NO | 17/550731 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 47/61 (20170801) A61K 47/542 (20170801) A61K 47/545 (20170801) Original (OR) Class A61K 49/0041 (20130101) A61K 49/0043 (20130101) A61K 49/0052 (20130101) A61K 49/0054 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168439 | Huang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Leaf Huang (Durham, North Carolina); Tyler GOODWIN (Chapel Hill, North Carolina); Rihe LIU (Chapel Hill, North Carolina); Lei MIAO (Chapel Hill, North Carolina) |
| ABSTRACT | The subject matter described herein is directed to methods of modifying the micro-environment of a target cell or The methods comprise systemically administering to a subject a composition comprising a vector, wherein the vector comprises a construct for the expression of a trap in the target cell, wherein the trap is expressed in the target cell thereby modifying the micro-environment. Also described herein are methods of reducing metastasis of a cancer comprising, systemically administering to a subject suffering from the cancer, a composition comprising a vector, wherein the vector comprises a construct for the expression of a trap, wherein the trap is delivered to and then expressed in tissue susceptible to metastasis, wherein metastasis of the cancer to the tissue is reduced. Compositions for carrying out the methods are also described. |
| FILED | Tuesday, November 30, 2021 |
| APPL NO | 17/537837 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/65 (20170801) A61K 47/6881 (20170801) Original (OR) Class A61K 48/005 (20130101) Peptides C07K 14/47 (20130101) C07K 16/2818 (20130101) C07K 16/2827 (20130101) C07K 2317/31 (20130101) C07K 2319/035 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168469 | FEINBERG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen E. FEINBERG (Ann Arbor, Michigan); Shiuhyang KUO (Dexter, Michigan); James Brian WASHINGTON (Saline, Michigan) |
| ABSTRACT | The present disclosure provides, in various aspects, a method of forming a prefabricated innervated pre-vascularized pre-laminated (PIPP) flap having a stoma or lumen. The method includes providing a cell construct including skin cells and/or mucosa cells. The method further includes forming an integrated in vivo composite at a donor site by grafting the cell construct onto a muscle. The method further includes stabilizing the composite on an obturator component. The method further includes developing a microvascular system in the composite by retaining it in vivo at the donor site for a predetermined period of time. The method further includes removing the obturator component from the stoma or lumen. In certain aspects, the present disclosure also provides a method of restoring a defect including damaged or surgically removed soft tissue using a PIPP flap. In certain aspect, the present disclosure also provides an obturator component for maintaining the stoma or lumen. |
| FILED | Thursday, December 02, 2021 |
| APPL NO | 17/540723 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/362 (20130101) A61L 27/3633 (20130101) A61L 27/3695 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0629 (20130101) C12N 2502/094 (20130101) C12N 2533/92 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168563 | VRABEC et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tina L. VRABEC (Cleveland, Ohio); Kevin L. KILGORE (Cleveland, Ohio); Jesse S. WAINRIGHT (Cleveland, Ohio); Niloy BHADRA (Cleveland, Ohio) |
| ABSTRACT | Accelerated recovery from direct current (DC) nerve block can be achieved using repolarization. A direct current (DC) waveform can be applied to a nerve for a time sufficient to achieve nerve block. The DC waveform can be switched to another DC waveform of reversed polarity, which can be applied for a second time, causing the nerve to enter a repolarization cycle to accelerate recovery time for the nerve. Moreover, simply applying a subthreshold DC waveform to the nerve for a time by itself can enhance a response of the nerve without blocking conduction in the nerve. |
| FILED | Friday, March 13, 2020 |
| APPL NO | 17/437873 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/205 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168571 | Shah et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Nishal Pradeepkumar Shah (Stanford, California); Eduardo Jose Chichilnisky (Stanford, California) |
| ABSTRACT | Systems and methods for artificial sight in accordance with embodiments of the invention are illustrated. One embodiment includes a retinal prosthesis system including an external controller, a scene imager, an eye imager, an implanted controller, and a stimulation interface in communication with the implanted controller, where the stimulation interface is positioned to stimulate a plurality of retinal ganglion cells (RGCs) of the eye, where the external controller is configured to obtain image data describing a scene from the scene imager, obtain eye position data from the eye imager, determine a field of view (FOV) in the scene based on the eye position data; where the implanted controller is configured to obtain the FOV from the external controller, continuously select stimulation pulses from a dictionary based on the FOV, and stimulate the plurality of RGCs using the stimulation interface in accordance with the selected stimulation pulses. |
| FILED | Monday, March 23, 2020 |
| APPL NO | 17/441261 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/08 (20130101) A61N 1/025 (20130101) A61N 1/0543 (20130101) A61N 1/36046 (20130101) Original (OR) Class A61N 1/37235 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168591 | ALBECK et al. |
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| FUNDED BY |
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| APPLICANT(S) | Nurotone Medical Ltd. (Rosh Ha'Ayin, Israel); NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | Nurotone Medical Ltd. (Rosh Ha'Ayin, Israel); NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Dan David ALBECK (Givat Shmuel, Israel); Claus Peter RICHTER (Skokie, Illinois); Yingyue XU (Chicago, Illinois); Xiaodong TAN (Wilmette, Illinois); Natan DAVIDOVICS (Rehovot, Israel) |
| ABSTRACT | Disclosed is a cochlear implant (Cl) and a method of generating stimulations for the CI. The Cl may include, at least one optical signal generator configured to generate a plurality of optical signals having a wavelength of at most 1600 nm, and a plurality of light emitters, for delivering the optical signals to different locations along a cochlear nerve. The method may further include optimizing the stimulation energy through selection of stimulation wavelengths and stimulation pulse shapes. |
| FILED | Thursday, February 06, 2020 |
| APPL NO | 17/427191 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/0603 (20130101) A61N 5/0622 (20130101) Original (OR) Class A61N 2005/063 (20130101) A61N 2005/0605 (20130101) A61N 2005/0626 (20130101) A61N 2005/0651 (20130101) A61N 2005/0659 (20130101) Optical Elements, Systems, or Apparatus G02B 6/4203 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168738 | Hodko et al. |
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| FUNDED BY |
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| APPLICANT(S) | Nexongen, Inc. (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dalibor Hodko (Poway, California); Nives Hodko (Poway, California); Anne-Laure Petit (San Diego, California); Ulrich Niemann (Seattle, Washington) |
| ABSTRACT | The invention relates to a microfluidic system based on active control of flow resistance and balancing pressures in microfluidic channels and an improved method for disposable microfluidic devices and cartridges for use in, but not limited to, in-vitro diagnostics. The microfluidic system and device of the invention does not utilize mechanical moving parts to control the fluid flow and has no external fluidic connection to the instrument or fluidics controller. |
| FILED | Monday, November 29, 2021 |
| APPL NO | 17/537439 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502746 (20130101) Original (OR) Class B01L 2200/16 (20130101) B01L 2300/0645 (20130101) B01L 2300/0819 (20130101) B01L 2400/082 (20130101) B01L 2400/0415 (20130101) B01L 2400/0463 (20130101) B01L 2400/0487 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 35/00069 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169580 | Kwon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of University of Califonia (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ohyun Kwon (Los Angeles, California); Andrew Smaligo (Los Angeles, California) |
| ABSTRACT | The present disclosure relates to methods of carbon-carbon bond fragmentation. |
| FILED | Monday, February 24, 2020 |
| APPL NO | 17/433518 |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 33/00 (20130101) C07B 37/00 (20130101) Original (OR) Class C07B 63/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169581 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zibo Li (Chapel Hill, North Carolina); David Nicewicz (Durham, North Carolina); Wei Chen (Chapel Hill, North Carolina) |
| ABSTRACT | The invention generally relates to methods of making substituted arenes via direct C—H, C—O, C—S, or C—N bond conversion and methods of synthesizing isotopically-labeled substituted arenes via direct carbon-halogen bond conversion. The invention also relates to anaerobic catalyst systems comprising an acridinium photocatalyst and a nucleophile selected from a halide, a cyanide, and an isotopically-labeled amine. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Thursday, February 27, 2020 |
| APPL NO | 17/434677 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/006 (20130101) B01J 35/004 (20130101) B01J 2231/46 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 59/001 (20130101) Original (OR) Class C07B 2200/05 (20130101) Acyclic or Carbocyclic Compounds C07C 17/12 (20130101) C07C 41/22 (20130101) C07C 45/63 (20130101) C07C 67/307 (20130101) C07C 231/12 (20130101) C07C 253/30 (20130101) C07C 269/06 (20130101) Heterocyclic Compounds C07D 213/69 (20130101) C07D 215/20 (20130101) C07D 231/56 (20130101) C07D 235/24 (20130101) C07D 239/96 (20130101) C07D 263/58 (20130101) C07D 311/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169607 | Buss et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| ASSIGNEE(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| INVENTOR(S) | Bonnie L. Buss (Fort Collins, Colorado); Garret Miyake (Fort Collins, Colorado); Chern-Hooi Lim (Boulder, Colorado); Max Kudisch (Fort Collins, Colorado) |
| ABSTRACT | The present invention provides photocatalysts, methods for their preparation, and methods for preparing linear polymers with high propagation rate. |
| FILED | Monday, March 30, 2020 |
| APPL NO | 17/593101 |
| CURRENT CPC | Heterocyclic Compounds C07D 209/86 (20130101) Original (OR) Class C07D 219/02 (20130101) C07D 265/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169628 | Zheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Guangrong Zheng (Gainesville, Florida); Daohong Zhou (Waldo, Florida); Pratik Pal (Gainesville, Florida); Xingui Liu (Gainesville, Florida); Dinesh Thummuri (Gainesville, Florida); Wanyi HU (Gainesville, Florida); Peiyi Zhang (Gainesville, Florida); Dongwen Lyu (Gainesville, Florida); Yaxia Yuan (Gainesville, Florida); Xuan Zhang (Gainesville, Florida) |
| ABSTRACT | The invention is directed towards compounds (e.g., Formula (I)), their mechanism of action, and methods of modulating proliferation activity, and methods of treating diseases and disorders using the compounds described herein (e.g., Formula (I)). |
| FILED | Friday, February 07, 2020 |
| APPL NO | 17/429207 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) Heterocyclic Compounds C07D 401/04 (20130101) Original (OR) Class C07D 417/12 (20130101) C07D 417/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169632 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Beibei Chen (Sewickley, Pennsylvania); Toren Finkel (Pittsburgh, Pennsylvania); Yuan Liu (Sewickley, Pennsylvania) |
| ABSTRACT | This document provides methods and materials for increasing or maintaining NMNAT2 polypeptide levels within cells. For example, compounds (e.g., organic compounds) having the ability to increase or maintain NMNAT2 polypeptide levels within cells, formulations containing compounds having the ability to increase or maintain NMNAT2 polypeptide levels within cells, methods for making compounds having the ability to increase or maintain NMNAT2 polypeptide levels within cells, methods for making formulations containing compounds having the ability to increase or maintain NMNAT2 polypeptide levels within cells, methods for increasing or maintain NMNAT2 polypeptide levels within cells, and methods for treating mammals (e.g., humans) having a condition responsive to an increase in NMNAT2 polypeptide levels are provided (or for preventing said condition). |
| FILED | Friday, February 21, 2020 |
| APPL NO | 17/432639 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) A61K 31/404 (20130101) A61K 31/405 (20130101) A61K 31/437 (20130101) A61K 31/444 (20130101) A61K 31/496 (20130101) A61K 31/4355 (20130101) A61K 31/4439 (20130101) A61K 31/4709 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 209/08 (20130101) C07D 209/18 (20130101) C07D 401/04 (20130101) C07D 401/12 (20130101) C07D 401/14 (20130101) Original (OR) Class C07D 405/12 (20130101) C07D 405/14 (20130101) C07D 409/12 (20130101) C07D 471/04 (20130101) C07D 487/06 (20130101) C07D 491/048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169669 | FAHRNI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
| ASSIGNEE(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
| INVENTOR(S) | Christoph J. FAHRNI (Atlanta, Georgia); M. Thomas MORGAN (Brookhaven, Georgia) |
| ABSTRACT | Several dimethylphosphine sulfide- and phosphine-containing compounds have been discovered that chelate copper(I) with high affinity. In certain embodiments, the compounds can be used to quantify copper(I) in complex biological systems. In another embodiment, the compounds can be used for the treatment of copper(I)-related illnesses and conditions. In still other embodiments, the compounds are ratiometric probes. |
| FILED | Monday, March 30, 2020 |
| APPL NO | 17/598929 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/34 (20130101) A61K 45/06 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/4093 (20130101) C07F 9/65586 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/84 (20130101) G01N 2800/2821 (20130101) G01N 2800/2835 (20130101) G01N 2800/7028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169673 | DESAI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Umesh R. DESAI (Richmond, Virginia); Balaji NAGARAJAN (Richmond, Virginia); Connor O'HARA (Richmond, Virginia); Daniel Kwame AFOSAH (Richmond, Virginia); Elsamani I. ABDELFADIEL (Richmond, Virginia); Jyothi SISTLA (Richmond, Virginia); Rahaman Navaz GANGJI (Richmond, Virginia); Ravikumar ONGOLU (Richmond, Virginia); Shravan MORLA (Richmond, Virginia); Viji SANKARANARAYANAN (Richmond, Virginia); Bhaumik B. PATEL (Richmond, Virginia); Chetna SHARON (Richmond, Virginia); Rio BOOTHELLO (Richmond, Virginia); Alberto VERA (Richmond, Virginia) |
| ABSTRACT | A group of specific sulfated flavonoid agents carrying cholesterol modification display promising in vivo anti-cancer activity through selective inhibition of cancer stem cells, and not of adult or hematopoietic stem cells. The compounds exhibit high potency, excellent oral bioavailability and a physiologically relevant therapeutic window. |
| FILED | Friday, March 06, 2020 |
| APPL NO | 17/436448 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Steroids C07J 17/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169683 | Niederweis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UAB RESEARCH FOUNDATION (Birmingham, Alabama) |
| ASSIGNEE(S) | THE UAB RESEARCH FOUNDATION (Birmingham, Alabama) |
| INVENTOR(S) | Michael Niederweis (Homewood, Alabama); Mikhail Pavlenok (Birmingham, Alabama) |
| ABSTRACT | Provided herein are mutant single-chain Mycobacterium smegmatis porin (Msp) and uses thereof. |
| FILED | Thursday, February 17, 2022 |
| APPL NO | 17/674140 |
| CURRENT CPC | Peptides C07K 14/35 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44743 (20130101) G01N 27/44756 (20130101) G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169684 | KLAPOETKE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Governors of the University of Alberta (Edmonton, Canada) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Governors of the University of Alberta (Edmonton, Canada) |
| INVENTOR(S) | Nathan KLAPOETKE (Ashburn, Virginia); Brian Yichiun CHOW (Cherry Hill, New Jersey); Edward BOYDEN (Chestnut Hill, Massachusetts); Gane KA-Shu WONG (Edmonton, Canada); Yongku Peter CHO (Vernon, Connecticut) |
| ABSTRACT | The invention, in some aspects relates to compositions and methods for altering cell activity and function and the introduction and use of light-activated ion channels. |
| FILED | Thursday, February 10, 2022 |
| APPL NO | 17/668766 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 41/0023 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) Peptides C07K 14/405 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5041 (20130101) G01N 33/5058 (20130101) G01N 33/48728 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169685 | SIMON et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MOREHOUSE SCHOOL OF MEDICINE (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Roger P. SIMON (Atlanta, Georgia); Zhigang XIONG (Atlanta, Georgia) |
| ABSTRACT | A system, including methods and compositions, for treatment of ischemia. |
| FILED | Friday, February 11, 2022 |
| APPL NO | 17/669844 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/439 (20130101) A61K 31/498 (20130101) A61K 31/4418 (20130101) A61K 31/4965 (20130101) A61K 38/16 (20130101) A61K 38/17 (20130101) A61K 38/1767 (20130101) A61K 45/06 (20130101) Peptides C07K 14/43518 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169688 | Walensky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Loren D. Walensky (Newton, Massachusetts); Ann Morgan Cathcart (Cambridge, Massachusetts); Gregory H. Bird (Pelham, New Hampshire) |
| ABSTRACT | This disclosure features structurally-stabilized and/or warhead-bearing structurally stabilized peptide inhibitors for targeting ubiquitin activating enzymes (E1). Also disclosed are methods of using such structurally-stabilized and warhead-bearing structurally stabilized peptides in the treatment of E1-expressing or -dependent cancers or diseases. Also provided are combination therapies N comprising such structurally-stabilized and/or warhead-bearing structurally stabilized peptide for the treatment of E1-expressing or -dependent diseases. |
| FILED | Friday, April 17, 2020 |
| APPL NO | 17/600468 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/4703 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169707 | Diskin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Rockefeller University (New York, New York); California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | The Rockefeller University (New York, New York); California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Ron Diskin (Pasadena, California); Anthony P. West (Pasadena, California); Michel Nussenzweig (New York, New York); Pamela J. Bjorkman (La Canada, California) |
| ABSTRACT | Embodiments of the present invention are directed to compositions and methods for anti-HIV (anti-CD4 binding site) broadly neutralizing antibodies having improved potency and breadth for neutralizing a range of HIV strains. Combinations of broadly neutralizing antibodies can also improve potency over a single antibody composition. |
| FILED | Wednesday, October 13, 2021 |
| APPL NO | 17/500171 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/1045 (20130101) C07K 16/1063 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169708 | HAMMOCK et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bruce D. HAMMOCK (Davis, California); Natalia VASYLIEVA (Davis, California); Jiexian DONG (Davis, California); Christophe MORISSEAU (West Sacramento, California); Dean R. MADDEN (Hanover, New Hampshire) |
| ABSTRACT | Provided are VHH or nanobodies that specifically bind to cystic fibrosis transmembrane conductance regulator (CFTR) inhibitory factor (Cif), and uses thereof for diagnosis and treatment of Pseudomonas infection. |
| FILED | Tuesday, December 07, 2021 |
| APPL NO | 17/544377 |
| CURRENT CPC | Peptides C07K 16/40 (20130101) C07K 16/1214 (20130101) Original (OR) Class C07K 2317/22 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/569 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56911 (20130101) G01N 2333/21 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169715 | KEANE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MIAMI (Miami, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert W. KEANE (Miami, Florida); W. Dalton DIETRICH (Miami, Florida); Nadine KERR (Miami, Florida); Shu WU (Miami, Florida); Juan Pablo DE RIVERO VACCARI (Miami, Florida) |
| ABSTRACT | The present invention provides compositions and methods for reducing inflammation in the lungs of a mammal that is afflicted by a condition that leads to inflammation in the lungs. The compositions and methods described herein include agents that inhibit inflammasome signaling in the mammal such as antibodies directed against inflammasome components used alone or in combination with extracellular vesicle uptake inhibitor(s). |
| FILED | Monday, February 14, 2022 |
| APPL NO | 17/670799 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/727 (20130101) A61K 39/3955 (20130101) A61K 39/39541 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) A61P 25/00 (20180101) A61P 25/14 (20180101) A61P 25/28 (20180101) A61P 29/00 (20180101) A61P 37/06 (20180101) Peptides C07K 16/18 (20130101) C07K 16/24 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169723 | Riddell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stanley R. Riddell (Sammamish, Washington); Lingfeng Liu (Seattle, Washington) |
| ABSTRACT | The present disclosure relates to tagged chimeric effector molecules and receptor molecules thereof for genetically engineering a host cell, wherein the recombinant host cell can be identified, isolated, sorted, induced to proliferate, tracked or eliminated. For example, a T cell may be recombinantly modified for use in adoptive immunotherapy. |
| FILED | Monday, May 24, 2021 |
| APPL NO | 17/329115 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 35/545 (20130101) A61K 38/1774 (20130101) A61K 38/2013 (20130101) A61K 38/2086 (20130101) A61K 2039/507 (20130101) Peptides C07K 14/705 (20130101) C07K 14/7051 (20130101) C07K 14/70521 (20130101) C07K 14/70578 (20130101) C07K 16/2803 (20130101) Original (OR) Class C07K 16/2818 (20130101) C07K 16/2878 (20130101) C07K 2319/03 (20130101) C07K 2319/20 (20130101) C07K 2319/22 (20130101) C07K 2319/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0637 (20130101) C12N 5/0638 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56972 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169724 | Woods et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Elliot C. Woods (Burlingame, California); Han Xiao (East Palo Alto, California); Carolyn R. Bertozzi (Stanford, California) |
| ABSTRACT | Provided are methods relating to the inhibition of inhibitory immune receptors. Aspects of the present disclosure include methods that include administering to an individual receiving an antibody therapy an inhibitory immune receptor inhibitor. Also provided are compositions and kits that find use, e.g., in practicing the methods of the present disclosure. |
| FILED | Friday, July 02, 2021 |
| APPL NO | 17/366512 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/32 (20130101) C07K 16/2803 (20130101) Original (OR) Class C07K 16/2851 (20130101) C07K 16/2887 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57492 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169735 | Huang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (CLEVELAND, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alex Yee-Chen Huang (Cleveland, Ohio); Agne Petrosiute (Cleveland, Ohio) |
| ABSTRACT | A method of sensitizing cancer to immunotherapy in a subject in need thereof includes administering to the subject a therapeutically effective amount of a CdK5 inhibitor to suppress immune checkpoint PD-L1. |
| FILED | Tuesday, September 21, 2021 |
| APPL NO | 17/480831 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/39541 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/70596 (20130101) C07K 16/2827 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/12 (20130101) Enzymes C12Y 207/11022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169980 | Finley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York); The Rockefeller University (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York); The Rockefeller University (New York, New York) |
| INVENTOR(S) | Lydia W.S. Finley (New York, New York); Bryce W. Carey (New York, New York); Craig B. Thompson (New York, New York); C. David Allis (New York, New York) |
| ABSTRACT | Disclosed herein are compositions, systems, and methods for modulating proliferation, differentiation and pluripotency of cells. |
| FILED | Thursday, September 02, 2021 |
| APPL NO | 17/464774 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/194 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0606 (20130101) Original (OR) Class C12N 5/0696 (20130101) C12N 2500/30 (20130101) C12N 2501/727 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169983 | Andersen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Jinior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jimena Andersen (Palo Alto, California); Fikri Birey (Palo Alto, California); Sergiu P. Pasca (Palo Alto, California) |
| ABSTRACT | Human pluripotent stem cells are differentiated in vitro into forebrain subdomain structures, which are then fused to generate an integrated system for use in analysis, screening programs, and the like. |
| FILED | Monday, February 14, 2022 |
| APPL NO | 17/671430 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/10 (20130101) C12N 5/0012 (20130101) C12N 5/0619 (20130101) C12N 5/0622 (20130101) Original (OR) Class C12N 5/0623 (20130101) C12N 5/0696 (20130101) C12N 2501/01 (20130101) C12N 2501/11 (20130101) C12N 2501/13 (20130101) C12N 2501/15 (20130101) C12N 2501/115 (20130101) C12N 2501/155 (20130101) C12N 2501/385 (20130101) C12N 2506/45 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5058 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169998 | Joung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | J. Keith Joung (Winchester, Massachusetts); Benjamin Kleinstiver (Medford, Massachusetts) |
| ABSTRACT | Engineered CRISPR-Cas9 nucleases with altered and improved PAM specificities and their use in genomic engineering, epigenomic engineering, and genome targeting. |
| FILED | Thursday, February 17, 2022 |
| APPL NO | 17/674558 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 2319/80 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 9/0071 (20130101) C12N 9/78 (20130101) C12N 9/80 (20130101) C12N 9/1007 (20130101) C12N 9/1029 (20130101) C12N 15/11 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220170012 | June et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Carl H. June (Merion Station, Pennsylvania); Yangbing Zhao (Lumberton, New Jersey) |
| ABSTRACT | The present invention relates to compositions and methods for generating RNA Chimeric Antigen Receptor (CAR) transfected T cells. The RNA-engineered T cells can be used in adoptive therapy to treat cancer. |
| FILED | Wednesday, February 16, 2022 |
| APPL NO | 17/673453 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 45/06 (20130101) A61K 48/00 (20130101) Peptides C07K 14/82 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220170026 | SMOLKE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christina D. SMOLKE (Menlo Park, California); Prashanth SRINIVASAN (Stanford, California) |
| ABSTRACT | Provided herein, among other things, is an engineered non-plant cell that produces a tropane alkaloid product, a precursor of a tropane alkaloid product, or a derivative of a tropane alkaloid product. A method for producing a tropane alkaloid, a precursor of a tropane alkaloid product, or a derivative of a tropane alkaloid product that makes use of the cell is also described. |
| FILED | Friday, March 06, 2020 |
| APPL NO | 17/436546 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) C12N 9/0022 (20130101) C12N 9/0032 (20130101) C12N 9/0071 (20130101) C12N 9/78 (20130101) C12N 9/88 (20130101) C12N 9/1007 (20130101) C12N 15/52 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 17/12 (20130101) C12P 17/188 (20130101) Enzymes C12Y 101/01027 (20130101) C12Y 101/01206 (20130101) C12Y 101/01236 (20130101) C12Y 101/01237 (20130101) C12Y 102/01003 (20130101) C12Y 104/0301 (20130101) C12Y 104/03021 (20130101) C12Y 104/03022 (20130101) C12Y 105/03017 (20130101) C12Y 106/02004 (20130101) C12Y 114/11011 (20130101) C12Y 201/01053 (20130101) C12Y 203/01001 (20130101) C12Y 203/01035 (20130101) C12Y 204/02028 (20130101) C12Y 205/01022 (20130101) C12Y 206/01057 (20130101) C12Y 207/07009 (20130101) C12Y 207/11001 (20130101) C12Y 305/01053 (20130101) C12Y 305/03001 (20130101) C12Y 305/03011 (20130101) C12Y 305/03012 (20130101) C12Y 401/01001 (20130101) C12Y 401/01017 (20130101) C12Y 401/01019 (20130101) C12Y 402/01051 (20130101) C12Y 403/01024 (20130101) C12Y 403/01025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220170066 | Belisle et al. |
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| FUNDED BY |
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| APPLICANT(S) | Gary P. Wormser (, None); Colorado State University Research Foundation (Forth Collins, Colorado); The United States of America, as represented by the secretary, Department of Health and Human Servic (Bethesda, Maryland) |
| ASSIGNEE(S) | Colorado State University Research Foundation (Fort Collins, Colorado); The United States of America, as represented by the secretary, Department of Health and Human Servic (Bethesda, Maryland) |
| INVENTOR(S) | John T. Belisle (Fort Collins, Colorado); Claudia R. Molins (Bethesda, Maryland); Gary P. Wormser (New York, New York) |
| ABSTRACT | The present disclosure provides a biosignature that distinguishes Lyme disease, including early Lyme disease, from STARI. The present disclosure also provides methods for detecting Lyme disease and STARI, as well as methods for treating subjects diagnosed with Lyme disease or STARI. |
| FILED | Tuesday, November 23, 2021 |
| APPL NO | 17/534170 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/04 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6848 (20130101) G01N 2333/20 (20130101) G01N 2800/20 (20130101) G01N 2800/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220170070 | LENG et al. |
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| FUNDED BY |
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| APPLICANT(S) | Fenfei LENG (Palmetto Bay, Florida); Zifang DENG (Miami, Florida) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (MIAMI, Florida) |
| INVENTOR(S) | Fenfei LENG (Palmetto Bay, Florida); Zifang DENG (Miami, Florida) |
| ABSTRACT | The present invention provides assays and methods for studying DNA topology and topoisomerases. The assays and methods utilize a circular plasmid DNA comprising one or more hairpin structures and the ability of T5 exonuclease (T5E) to digest the circular plasmid DNA in a specific configuration. The assays and methods can be used as a high throughput screening for inhibitors of, for example, DNA gyrases and DNA topoisomerases I for anticancer drug and antibiotics discovery. |
| FILED | Monday, February 14, 2022 |
| APPL NO | 17/670738 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/44 (20130101) C12Q 1/533 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 2021/6439 (20130101) G01N 2500/04 (20130101) G01N 2500/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220170073 | Schwartz et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois); EMD Millipore Corporation (Burlington, Massachusetts) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois); EMD Millipore Corporation (Burlington, Massachusetts) |
| INVENTOR(S) | David A. Schwartz (Encinitas, California); Jimmy Williams (Santee, California); Xinfang Zhao (San Diego, California); Chunfang Zhao (San Diego, California); William B. Busa (Bahama, North Carolina); Stephen J. Kron (Oak Park, Illinois); Amy Catherine Flor (Chicago, Illinois) |
| ABSTRACT | The present disclosure is directed to methods and/or uses of oligonucleotide conjugates for assays and flow cytometry detections and related systems and/or kits. Certain methods are directed to a method for detecting one or more biological targets of a sample in a detection assay, comprising: providing a molecular probe, comprising a binding moiety and an oligonucleotide sequence, to a sample comprising one or more biological targets; binding the one or more biological targets with the binding moiety; providing a detectable component to the sample, wherein the detectable component comprises a signal generating moiety conjugated to an oligonucleotide sequence complementary to the oligonucleotide sequence of the molecular probe; hydridizing the oligonucleotide sequence of the target-bound molecular probe to the detectable component; and detecting a signal generated from the hydridized detectable component. Various other embodiments, applications etc. are disclosed herein. |
| FILED | Wednesday, July 07, 2021 |
| APPL NO | 17/369771 |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6804 (20130101) Original (OR) Class C12Q 1/6834 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220170077 | Church et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | George M. Church (Brookline, Massachusetts); Jehyuk Lee (Allston, Massachusetts); Daniel Levner (Boston, Massachusetts); Michael Super (Lexington, Massachusetts) |
| ABSTRACT | Methods of analyzing nucleic acids of a cell are provided. |
| FILED | Tuesday, February 15, 2022 |
| APPL NO | 17/671803 |
| CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6804 (20130101) C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6816 (20130101) C12Q 1/6837 (20130101) C12Q 1/6844 (20130101) C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220170087 | Tung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Steve TUNG (Fayetteville, Arkansas); Bo MA (Fayetteville, Arkansas); Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steve Tung (Fayetteville, Arkansas); Bo Ma (Fayetteville, Arkansas) |
| ABSTRACT | A method of DNA base-calling from a nanochannel DNA sequencer. The method includes building a reference map and preparing an unknown sequence of DNA prior to the final step of data matching. The reference map includes a series of reference characters, such as numbers, that describe the change in tunneling current of a DNA strand with a known sequence. A DNA strand of unknown sequence is prepared so that the change in electrical measurement can also be described numerically. The section of match between the DNA strand of unknown sequence and the reference map is used to determine the sequence of the DNA strand. |
| FILED | Wednesday, March 18, 2020 |
| APPL NO | 17/441094 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/04 (20130101) G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220170097 | Boroughs et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Angela Boroughs (Boston, Massachusetts); Nemo Marjanovic (Cambridge, Massachusetts); Aviv Regev (Cambridge, Massachusetts); Marcela Maus (Boston, Massachusetts); Tamara Ouspenskaia (Cambridge, Massachusetts) |
| ABSTRACT | The invention relates to gene expression profiles and signatures of CAR T cells. The invention provides methods and compositions of CAR T cells and populations. The invention provides assays and methods of screening subjects to assess efficacy and safety of CAR T cell treatments and therapies. The invention provides assays and methods of engineering and/or administering CAR T cells to promote efficacy and safety. |
| FILED | Tuesday, October 29, 2019 |
| APPL NO | 17/289844 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6881 (20130101) Original (OR) Class C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/505 (20130101) G01N 33/5023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220170104 | Meyerson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew Meyerson (Concord, Massachusetts); Aleksandar Kostic (Brookline, Massachusetts) |
| ABSTRACT | Methods for predicting risk of developing colorectal cancer, for treating colorectal cancer, and reducing risk of developing colorectal cancer. |
| FILED | Friday, June 11, 2021 |
| APPL NO | 17/345311 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) C12Q 1/6886 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220170109 | Yeh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Jen Jen Yeh (Chapel Hill, North Carolina); Richard Moffitt (Stony Brook, New York); Naim Ur Rashid (Raleigh, North Carolina) |
| ABSTRACT | Provided are methods for identifying pancreatic cancer subtypes in a subject and treating the same. In some embodiments, the method comprise obtaining gene expression levels for each of the following genes in the biological sample: GPR87, KRT6A, BCAR3, PTGES, 1TGA3, C16orf74, S100A2, KRT5, REG4, ANXA10, GATA6, CLDN18, LGALS4, DDC, SLC40A1, CLRN3; performing pair-wise comparisons of gene expression levels for combinations of these genes, and calculating a Raw Score for the biological sample, wherein the Raw Score is indicative of the pancreatic cancer subtype in the subject. Also provided are methods for identifying differential treatment strategies for subjects diagnosed with PDAC, methods for treating PDAC patients based on the subtype of PD AC the patients have; and methods for classifying subjects diagnosed with PDAC as having a basal-like subtype or a classical subtype of PDAC. |
| FILED | Wednesday, April 01, 2020 |
| APPL NO | 17/601002 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220170116 | Green et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Alexander A. Green (Chestnut Hill, Massachusetts); Peng Yin (Cambridge, Massachusetts); James J. Collins (Newton, Massachusetts); Jongmin Kim (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides novel and versatile classes of riboregulators, including inter alia activating and repressing riboregulators, switches, and trigger and sink RNA, and methods of their use for detecting RNAs in a sample such as a well and in modulating protein synthesis and expression. |
| FILED | Thursday, September 16, 2021 |
| APPL NO | 17/477456 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1138 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6897 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220170908 | Wyss-Coray et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Anton WYSS-CORAY (Stanford, California); David GATE (Stanford, California); Mark DAVID (Stanford, California); Naresha SALIGRAMA (Stanford, California); David A. CASIMIR (Stanford, California); The Board of Trustees of the Leland Standford Junior Inivesity (Stanford, California); U.S Government as represented by The Department of Veterans Affair (Washibton, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anton Wyss-Coray (Stanford, California); David Gate (Stanford, California); Mark Davis (Stanford, California); Naresha Saligrama (Stanford, California) |
| ABSTRACT | Provided herein am compositions and methods for characterizing and treating neurodegenerative disease. In particular, provided herein are compositions and methods for measuring T cell markers associated with Alzheimer's disease. |
| FILED | Wednesday, March 25, 2020 |
| APPL NO | 17/442387 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Peptides C07K 14/7051 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/505 (20130101) Original (OR) Class G01N 33/6896 (20130101) G01N 2333/522 (20130101) G01N 2800/2821 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220170944 | Dohil et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ranjan Dohil (San Diego, California); Seema S. Aceves (Solana Beach, California) |
| ABSTRACT | The disclosure relates to diagnostic and biomarker panels for determining an eosinophilic disease or disorder. More particularly, the disclosure provides methods and diagnostics for determining eosinophilic esophagitis. |
| FILED | Friday, January 31, 2020 |
| APPL NO | 17/310265 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/37 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) G01N 33/6893 (20130101) Original (OR) Class G01N 2333/8132 (20130101) G01N 2800/24 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220170947 | Ching et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Institute at Nationwide Children's Hospital (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christina B. Ching (Columbus, Ohio); Michael B. Becknell (Westerville, Ohio); Ashley R. Jackson (Grove City, Ohio); Sudipti Gupta (Columbus, Ohio); Janae Preece (Grosse Pointe Park, Michigan) |
| ABSTRACT | A method of diagnosing and treating urinary tract obstruction that includes obtaining a urine sample from a human patient; detecting whether a predetermined uroepithelial peptide or predetermined urinary protein is present in the urine sample by either contacting the urine sample with an anti-uroepithelial peptide antibody and detecting binding between the uroepithelial peptide and the antibody or contacting the urine sample with an anti-urinary protein antibody and detecting binding between the urinary protein and the antibody; diagnosing the patient with urinary tract obstruction when the presence of either the predetermined uroepithelial peptide or predetermined urinary protein is detected; and operatively or non-operatively treating the patient to correct or remove the urinary tract obstruction. |
| FILED | Friday, July 31, 2020 |
| APPL NO | 17/625267 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) Original (OR) Class G01N 2800/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220171421 | RUEGSEGGER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark RUEGSEGGER (Dublin, Ohio); Sandra METZLER (West Jefferson, Ohio); Luke LEMMERMAN (St. Mary's, Ohio); Jenna TABBAA (Westlake, Ohio); Ilya GULKO (Richmond Heights, Ohio); Kezhuo WANG (Los Angeles, California); Riley HULBERT (Madison, Wisconsin); Lauren MERSHAD (Dayton, Ohio); Kaitlin FINCH (Powell, Ohio) |
| ABSTRACT | Various implementations include an assistive driving device including a base, a first post, a second post, a third post, and a selector. The first post is for receiving a portion of a palm of a hand of a user and has a proximal end and a distal end. The second post has a proximal end and a distal end. The third post has a proximal end and a distal end. The proximal ends of the first, second, and third posts are coupled to the base. The second post and the third post are positioned to receive a portion of an arm of the user. The selector is spaced apart from the first post and positioned such that the selector is actuatable with a dorsum of the hand of the user. |
| FILED | Friday, April 19, 2019 |
| APPL NO | 17/434660 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 4/00 (20130101) Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles B60K 35/00 (20130101) B60K 37/06 (20130101) B60K 2370/131 (20190501) B60K 2370/157 (20190501) Motor Vehicles; Trailers B62D 1/22 (20130101) Control Devices or Systems Insofar as Characterised by Mechanical Features Only G05G 1/01 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20220167913 | Reed et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | David A. Reed (Baltimore, Maryland); George C. Emmett (Wilmington, Delaware) |
| ABSTRACT | In an example, a method of detecting cyanide exposure of an individual comprises measuring a thiocyanate level of the individual, and comparing the measured thiocyanate level to a preset thiocyanate threshold to determine whether the measured thiocyanate level is above the preset thiocyanate threshold indicating a level of cyanide poisoning requiring immediate medical assessment. |
| FILED | Tuesday, February 15, 2022 |
| APPL NO | 17/671925 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/4845 (20130101) Original (OR) Class A61B 5/14551 (20130101) A61B 10/0051 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168225 | EBER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CureVac AG (Tübingen, Germany) |
| ASSIGNEE(S) | CureVac AG (Tübingen, Germany) |
| INVENTOR(S) | Fabian Johannes EBER (Stuttgart, Germany); Benyamin YAZDAN PANAH (Tübingen, Germany); Stefanie SEWING (Tübingen, Germany); Thomas KETTERER (Gomaringen, Germany); Thorsten MUTZKE (Reutlingen, Germany); Tilmann ROOS (Kusterdingen, Germany); Michael SONNTAG (Tübingen, Germany); Michael WIGGENHORN (München, Germany); Katharina KOLLAND (Augsburg, Germany) |
| ABSTRACT | The present invention is directed to a storage-stable formulation of long-chain RNA. In particular, the invention concerns a dry powder composition comprising a long-chain RNA molecule. The present invention is furthermore directed to methods for preparing a dry powder composition comprising a long-chain RNA molecule by spray-freeze drying. The invention further concerns the use of such a dry powder composition comprising a long-chain RNA molecule in the preparation of pharmaceutical compositions and vaccines, to a method of treating or preventing a disorder or a disease, to first and second medical uses of such a dry powder composition comprising a long-chain RNA molecule and to kits, particularly to kits of parts, comprising such a dry powder composition comprising a long-chain RNA molecule. |
| FILED | Monday, February 21, 2022 |
| APPL NO | 17/676586 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/19 (20130101) A61K 9/1682 (20130101) Original (OR) Class A61K 31/7105 (20130101) A61K 48/005 (20130101) A61K 48/0091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168392 | Eichenbaum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Janssen Pharmaceutica NV (Beerse, Belgium) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gary Eichenbaum (Belle Mead, New Jersey); Sanchita Ghosh (North Potomac, Maryland); Alfred Tonelli (Upper Nyack, New York) |
| ABSTRACT | Methods of mitigating vascular injury, promoting organ and hematopoietic recovery, accelerating vascular recovery, and enhancing survival in a subject treated with radiation therapy or chemotherapy are described. In particular, an effective amount of a thrombopoietin (TPO) mimetic, such as RWJ-800088, is used at the appropriate times relative to the Total Body Irradiation or Chemotherapy exposure to achieve these prophylactic and/or therapeutic benefits. |
| FILED | Friday, February 18, 2022 |
| APPL NO | 17/651675 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/196 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 47/60 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 39/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168411 | Porter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of American as Represented by the Secretary of the Navy (Silver Spring, Maryland) |
| ASSIGNEE(S) | The United States of American as Represented by the Secretary of the Navy (Silver Spring, Maryland) |
| INVENTOR(S) | Kevin R Porter (Boyds, Maryland); Maya Willams (Silver Spring, Maryland); Raviprakash Kanakatte (Clarksville, Maryland); Dawn Weir (Kensington, Maryland); Daniel Ewing (Laurel, Maryland); Appavu K Sundaram (, None) |
| ABSTRACT | The invention reported here relates to a method for preparation of inactivated SARS-CoV-2 vaccine by exposing the virus (SARS-CoV-2) to a predetermined concentration of an inactivating psoralen compound, and a preselected intensity of ultraviolet A (UVA) radiation for a preselected time period long enough to render the virus inactive but short enough to prevent degradation of its antigenic characteristics. |
| FILED | Wednesday, December 01, 2021 |
| APPL NO | 17/539667 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/55572 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168810 | Watson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | 3D Systems, Inc. (Rock Hill, South Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan Watson (Santa Monica, California); Kirt Winter (San Diego, California) |
| ABSTRACT | A three-dimensional (3D) printing system for manufacturing a three-dimensional (3D) article includes a support powder dispenser containing support powder, a metal powder dispenser containing metal powder, a build plate, a beam system, and a controller. The controller is configured to (1) receive information defining a two-dimensional (2D) slice of the 3D article, (2) position the build plate to receive a new layer of metal powder, (3) operate the metal powder dispenser to dispense the new layer of metal powder, the new layer of metal powder spanning the 2D slice and extending beyond the boundaries to define a zone of unfused powder, (4) operate the beam system to selectively fuse the new layer of powder over an area corresponding to the 2D slice, (5) operate the support powder dispenser to dispense a bounding contour of support powder proximate to or overlapping the zone of unfused powder. |
| FILED | Monday, August 16, 2021 |
| APPL NO | 17/402783 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/05 (20220101) B22F 10/28 (20210101) Original (OR) Class B22F 10/85 (20210101) B22F 2302/256 (20130101) B22F 2304/10 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168855 | Tindal |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as Represented by the Secretary of the Air Forece (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mitchell Tindal (Hartland, Wisconsin) |
| ABSTRACT | A tripod jack cylinder removal tool including a lifting eyebolt attached through an up flange and further through and up flange aperture to a lock nut. The flange is secured to a pipe at a pipe top end, the pipe further having a bottom end wherein a down flange having a down flange aperture is attached to the pipe and a bolt having threads protrudes through a down flange aperture. |
| FILED | Thursday, February 17, 2022 |
| APPL NO | 17/674278 |
| CURRENT CPC | Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 19/04 (20130101) Original (OR) Class Hoisting, Lifting, Hauling or Pushing, Not Otherwise Provided For, e.g Devices Which Apply a Lifting or Pushing Force Directly to the Surface of a Load B66F 13/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168997 | Nataraj et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Army Combat Capabilities Development Command, Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Latha Nataraj (Chadds Ford, Pennsylvania); Heather A. Murdoch (Baltimore, Maryland) |
| ABSTRACT | A composite structure includes a plurality of laminate layers containing resin reinforced with carbon fiber; and a laminate coated with a metallic layer integrated with a transition metal oxide that is laid up as a topmost layer of the plurality of laminate layers. The plurality of laminate layers and the coated laminate are cured to form a composite material in a defined process to (i) integrate the transition metal oxide in the composite material, (ii) utilize transformed magnetic properties of the transition metal oxide to integrate the transition metal oxide into the metallic layer to coat the laminate, and (iii) utilize transformed optical properties of the transition metal oxide to achieve infrared shielding beyond a phase transition temperature of the transition metal oxide. |
| FILED | Tuesday, December 01, 2020 |
| APPL NO | 17/108437 |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 15/14 (20130101) B32B 15/043 (20130101) Original (OR) Class B32B 27/18 (20130101) B32B 2262/106 (20130101) B32B 2307/208 (20130101) B32B 2307/416 (20130101) B32B 2311/22 (20130101) B32B 2313/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169324 | PANTALEO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard PANTALEO (Pittsburgh, Pennsylvania); Dimitrios APOSTOLOPOULOS (Pittsburgh, Pennsylvania); Edward MUTSCHLER (Pittsburgh, Pennsylvania); Matthew GLISSON (Pittsburgh, Pennsylvania) |
| ABSTRACT | The Reconfigurable Wheel-Track (RWT) is a novel mechanism that allows a wheel to transform into a track, and vice-versa. The wheel permits a vehicle to travel quickly over smooth and semi-rough terrain, then, on-the-fly, transform rapidly into a powered track for crossing extreme terrain. The reconfigurable wheel-track consists of several main components: an outer tire/tread, drive mechanisms for the wheel and track, support mechanisms for the outer tread when in either wheel mode or track mode, and a reconfiguration mechanism that facilitates the transformation from a wheel to a track and vice-versa. The reconfigurable wheel-track includes sensing, actuation, and controls to facilitate efficient and effective transition from wheel to track and vice-versa, and securely maintain each shape. |
| FILED | Wednesday, April 29, 2020 |
| APPL NO | 17/433901 |
| CURRENT CPC | Vehicle Wheels; Castors; Axles for Wheels or Castors; Increasing Wheel Adhesion B60B 19/02 (20130101) Motor Vehicles; Trailers B62D 55/04 (20130101) Original (OR) Class B62D 55/14 (20130101) B62D 55/084 (20130101) B62D 55/125 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169345 | Cohen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nathan David Cohen (Encinitas, California); Nathan Todd Miller (San Diego, California) |
| ABSTRACT | A mooring system comprising: a ballast platform; and a chain comprising a plurality of links that are pivotally connected to each other via parallel pivot pins such that the chain is configured to not rotate about a vertical axis that is orthogonal to axes of rotation of the pivot pins, wherein the chain has proximal and distal ends, and wherein the proximal end is attached to a top of the ballast platform and the distal end is configured to be attached to a buoyant object. |
| FILED | Wednesday, December 02, 2020 |
| APPL NO | 17/109290 |
| CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 21/20 (20130101) B63B 39/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169525 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Houston System (Houston, Texas); National Central University (Taoyuan City, Taiwan) |
| ASSIGNEE(S) | University of Houston System (Houston, Texas); National Central University (Taoyuan City, Taiwan) |
| INVENTOR(S) | T. Randall Lee (Houston, Texas); Riddhiman Medhi (Houston, Texas); Sang Ho Lee (Houston, Texas); Chien-Hung Li (Kaohsiung City, Taiwan); Allan J. Jacobson (Houston, Texas); Tai-Chou Lee (Taoyuan City, Taiwan) |
| ABSTRACT | The present disclosure relates to a strategy to synthesize antimony- and zinc-doped tin oxide particles with tunable band gap characteristics. The methods yield stable and monodispersed particles with great control on uniformity of shape and size. The methods produce undoped and antimony and zinc-doped tin oxide stand-alone and core-shell particles, both nanoparticles and microparticles, as well as antimony and zinc-doped tin oxide shells for coating particles, including plasmonic core particles. |
| FILED | Friday, January 31, 2020 |
| APPL NO | 17/425783 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/14 (20130101) B01J 23/18 (20130101) B01J 23/52 (20130101) B01J 35/004 (20130101) B01J 35/0006 (20130101) B01J 37/04 (20130101) B01J 37/08 (20130101) B01J 37/0213 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 19/02 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/54 (20130101) C01P 2002/72 (20130101) C01P 2002/84 (20130101) C01P 2002/85 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101) C01P 2004/51 (20130101) C01P 2004/64 (20130101) C01P 2006/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169684 | KLAPOETKE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Governors of the University of Alberta (Edmonton, Canada) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Governors of the University of Alberta (Edmonton, Canada) |
| INVENTOR(S) | Nathan KLAPOETKE (Ashburn, Virginia); Brian Yichiun CHOW (Cherry Hill, New Jersey); Edward BOYDEN (Chestnut Hill, Massachusetts); Gane KA-Shu WONG (Edmonton, Canada); Yongku Peter CHO (Vernon, Connecticut) |
| ABSTRACT | The invention, in some aspects relates to compositions and methods for altering cell activity and function and the introduction and use of light-activated ion channels. |
| FILED | Thursday, February 10, 2022 |
| APPL NO | 17/668766 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 41/0023 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) Peptides C07K 14/405 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5041 (20130101) G01N 33/5058 (20130101) G01N 33/48728 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169811 | Omenetto et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Fiorenzo G. Omenetto (Lexington, Massachusetts); Yu Wang (Medford, Massachusetts); Beom Joon Kim (Medford, Massachusetts) |
| ABSTRACT | The present disclosure relates to reversibly wrinkled silk-based compositions. The provided compositions are tunable and the reversible wrinkles are sensitive to water vapor, methanol vapor, and UV irradiation. The present disclosure also provides methods for making and using the same. |
| FILED | Friday, March 27, 2020 |
| APPL NO | 17/593876 |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 7/0427 (20200101) Original (OR) Class C08J 2383/04 (20130101) C08J 2489/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220170116 | Green et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Alexander A. Green (Chestnut Hill, Massachusetts); Peng Yin (Cambridge, Massachusetts); James J. Collins (Newton, Massachusetts); Jongmin Kim (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides novel and versatile classes of riboregulators, including inter alia activating and repressing riboregulators, switches, and trigger and sink RNA, and methods of their use for detecting RNAs in a sample such as a well and in modulating protein synthesis and expression. |
| FILED | Thursday, September 16, 2021 |
| APPL NO | 17/477456 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1138 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6897 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220170117 | Lucks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Julius B. Lucks (Evanston, Illinois); Walter M. Thavarajah (Chicago, Illinois); Adam D. Silverman (Chicago, Illinois); Michael C. Jewett (Evanston, Illinois) |
| ABSTRACT | Disclosed are methods and systems for detecting fluoride as a target molecule in a test sample which utilize a cell-protein synthesis (CFPS) reaction and an engineered fluoride-sensing riboswitch. The components used in the disclosed methods and systems may be dried or lyophilized and may be present or immobilized on a paper substrate. |
| FILED | Tuesday, March 03, 2020 |
| APPL NO | 17/593026 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) C12N 2310/16 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6897 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/78 (20130101) G01N 33/84 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220170432 | Koehler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Frederick B. Koehler (Tucson, Arizona); Jacob A. Pinello-Benavides (Vail, Arizona); Curtis S. Copeland (Tucson, Arizona); Isaiah M. McNeil (Sahuarita, Arizona); Paul Kadlec (Vail, Arizona); Lauren E. Brunacini (Tucson, Arizona); Mark T. Langhenry (Tucson, Arizona) |
| ABSTRACT | A rocket motor has an electrically operated propellant initiator for a propellant grain that includes an electrode arrangement configured to concentrate an electric field at an ignition electrode for igniting an electrically operated propellant. The rocket motor includes a combustion chamber containing at least one propellant grain and an electrically operated propellant initiator operatively coupled to the propellant grain to initiate combustion of the propellant grain. The electrically operated propellant initiator includes the electrically operated propellant and at least one pair of electrodes configured to ignite the electrically operated propellant. The pair of electrodes includes a ground plane electrode and an ignition electrode. When an electrical input is applied to the electrically operated propellant initiator, the electric field is concentrated at the ignition electrode to ignite the electrically operated propellant at the location where the ignition electrode is arranged. |
| FILED | Saturday, November 28, 2020 |
| APPL NO | 17/106089 |
| CURRENT CPC | Jet-propulsion Plants F02K 9/38 (20130101) F02K 9/94 (20130101) F02K 9/95 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220170438 | Filardo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Pliant Energy Systems LLC (Brooklyn, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Benjamin Pietro Filardo (New York, New York); Daniel S. Zimmerman (Brooklyn, New York); Michael I. Weaker (Brooklyn, New York) |
| ABSTRACT | The VEHICLE WITH TRAVELING WAVE THRUST MODULE APPARATUSES, METHODS AND SYSTEMS include force or forces applied to an arc-like flexible sheet-like material to create a deformed crenated strip fin with strained-deformations. The strained-deformations take on a sinusoid-like form that express the internal energy state of the flexible sheet-like material after it has been configured into a crenated strip fin. After being incorporated into a mechanism with couplings that prevent the crenated strip fin from returning to its un-strained state, the strained-deformations persist. Actuators may be used to sequentially rotate vertebrae attached to the fins causing the travel of sinusoid-like deformations along the fins. The fin, fin actuator or actuators, power source and central controller may be incorporated into a thrust module. Two thrust modules coupled to a central body via roll actuators and flexible coupling members may form a vehicle with exceptional maneuverability. |
| FILED | Thursday, November 18, 2021 |
| APPL NO | 17/530190 |
| CURRENT CPC | Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 35/00 (20130101) Vehicles for Use Both on Rail and on Road; Amphibious or Like Vehicles; Convertible Vehicles B60F 3/0007 (20130101) Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 50/60 (20190201) Motor Vehicles; Trailers B62D 57/02 (20130101) Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/08 (20130101) Lighter-than Air Aircraft B64B 1/00 (20130101) Machines or Engines for Liquids F03B 13/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220170722 | Lotti et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew J. Lotti (Tucson, Arizona); Shawn P. Burke (Vail, Arizona); Donald G. Messitt (Folsom, California); Jaylan S. Jones (Tucson, Arizona) |
| ABSTRACT | A projectile includes a wing structure to form both an inlet that intakes air for combustion by a propulsion system of the projectile during an initial range of flight, and a lift surface for the projectile after the propulsion engine of the propulsion system burns out. The wing structure acts as both the inlet and the lift surface to enable both a long range and an optimal time of flight for the projectile to the target. The wing structure includes at least one wing that is movable from a folded position, in which the wing extends along a propulsion body section of the projectile to define the inlet, to a deployed position, in which the wing extends outwardly from the propulsion body section to form the lift surface. Any number of wings may be provided and the wings may be simultaneously deployed or sequentially deployed depending on the application. |
| FILED | Monday, August 02, 2021 |
| APPL NO | 17/379149 |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 10/14 (20130101) Original (OR) Class F42B 15/105 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220171013 | KASSAS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Zak KASSAS (Irvine, California); Joe KHALIFE (Irvine, California); Ali ABDALLAH (Irvine, California) |
| ABSTRACT | System and device configurations, and processes are provided for determining position based on low Earth orbit (LEO) satellite signals. Frameworks described herein can include performing Doppler frequency measurement for received quadrature phase shift keying (QPSK) signals. The framework may include channel tracking operations to determine Doppler shift measurements, a navigation filter operation to determine clock drift based on each Doppler shift measurement from each channel tracking loop, and determining position of a device based on LEO satellite signal sources. Frameworks described herein are also provided for carrier phase differential (CD)—low Earth orbit (LEO) (CD-LEO) measurements that may utilize a base and a rover without requiring prior knowledge of rover position. Embodiments can also cancel effects of ionospheric and tropospheric delays on the carrier phase and CD-LEO measurements. |
| FILED | Wednesday, April 15, 2020 |
| APPL NO | 17/604154 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/009 (20130101) G01S 5/0246 (20200501) G01S 5/0284 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220171077 | KASSAS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Zak KASSAS (Irvine, California); Josh MORALES (Irvine, California); Joe KHALIFE (Irvine, California) |
| ABSTRACT | Systems, device configurations, and processes are provided for tracking and navigation using low-earth orbit satellite (LEO) signals. Embodiments are provided to track LEO satellites in the absence or during interrupted service by global position sources (e.g., GNSS). Operations and a framework are provided to use low-earth orbit (LEO) downlink transmissions as a source of positioning data. Operations can include performing a Doppler frequency measurement on received satellite downlink transmissions to determine a pseudorange rate measurement for a vehicle relative to at least one LEO satellite. Pseudorange rate measurements may be used to correct vehicle position data of a vehicles inertial navigation system (INS) and for control/navigation of the vehicle. Embodiments allow for simultaneous tracking of LEO satellites and navigation of a vehicle, such as an unmanned aerial vehicle. Embodiments are also directed to employing a propagation model for LEO position and velocity within a simultaneous tracking and navigation (STAN) framework. |
| FILED | Wednesday, April 15, 2020 |
| APPL NO | 17/604157 |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/165 (20130101) G01C 21/188 (20200801) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/49 (20130101) Original (OR) Class G01S 19/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220171105 | Ko et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yeong Hwan Ko (Grand Prairie, Texas); Neelam Gupta (Bethesda, Maryland); Robert Magnusson (Arlington, Texas) |
| ABSTRACT | A tunable optical filter comprises a resonant grating layer having an aperiodic pattern, an optional sublayer, a waveguide layer, and a substrate layer, wherein at least one of the waveguide layer and the sublayer, when present is inhomogenous. In some instances, the optional sublayer and/or the waveguide layer may comprise a thickness gradient. Incident light may be filtered and/or reflected by an optical filter, for instance a band of incident electromagnetic radiation has 90% or greater transmittance or reflectance and adjacent bands of incident electromagnetic radiation have 10% or less transmittance or reflectance, respectively. |
| FILED | Friday, September 10, 2021 |
| APPL NO | 17/471717 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/1814 (20130101) Original (OR) Class G02B 5/1857 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220171204 | WU et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chensheng WU (Greenbelt, Maryland); Jonathan KO (Davidsonville, Maryland); John R. RZASA (College Park, Maryland); Christopher C. DAVIS (Annapolis, Maryland); Daniel PAULSON (Hyattsville, Maryland) |
| ABSTRACT | An afocal sensor assembly detects a light beam with an aberrated wavefront. The afocal sensor assembly is configured to provide sorted four-dimensional (4D) light field information regarding the light beam, for example, via one or more plenoptic images. Based on the 4D light field information, a lossy reconstruction of an aberrated wavefront for one or more actuators of an adaptive optics (AO) device is performed. The AO device can be controlled based on the lossy reconstruction to correct the wavefront of the light beam. In some embodiments, the aberrated wavefront is due to passage of the light beam through atmospheric turbulence, and the lossy reconstruction and correction using the AO device is performed in less than 1.0 ms. The lossy reconstruction of the aberrated wavefront can have a phase accuracy in a range of λ/2 to λ/30. |
| FILED | Thursday, December 02, 2021 |
| APPL NO | 17/540644 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 3/0037 (20130101) G02B 27/0025 (20130101) G02B 27/0916 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/70 (20170101) G06T 7/557 (20170101) G06T 2207/10052 (20130101) Pictorial Communication, e.g Television H04N 5/22541 (20180801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220171224 | Idehenre et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Ighodalo U. Idehenre (Tipp City, Ohio); Dean R. Evans (Beavercreek, Ohio) |
| ABSTRACT | A transparent device for use in optical applications, and methods for using and manufacturing the device are disclosed. The device generally requires several layers, including (i) a first layer comprising a transparent conductive oxide (such as indium tin oxide (ITO)), (ii) a second layer comprising a transparent semiconductor (e.g., a pn-heterojunction or a pn-homojunction), the second layer having a surface facing the first layer, (iii) a third layer comprising a liquid crystal (such as E7), the third layer having a surface facing the second layer, and (iv) a fourth layer comprising either a second transparent conductive oxide or a second transparent semiconductor, the fourth layer having a surface facing the third layer. When light illuminates a surface of the transparent metal oxide pn-heterojunction or transparent metal oxide pn-homojunction, it induces photoconductivity, modifying the surface charges. |
| FILED | Tuesday, February 22, 2022 |
| APPL NO | 17/651969 |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/1354 (20130101) Original (OR) Class G02F 1/1357 (20210101) G02F 1/133784 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220171293 | Krishnaswamy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sridhar Krishnaswamy (Lake Forest, Illinois); Heming Wei (Shanghai, China PRC); Wisnu Hadibrata (Evanston, Illinois); Koray Aydin (Wilmette, Illinois) |
| ABSTRACT | Methods of fabricating an object via direct laser lithography are provided. In embodiments, such a method comprises illuminating, via an optical fiber having an end facet and a metalens directly on the end facet, a location within a photosensitive composition from which an object is to be fabricated with light, thereby inducing a multiphoton process within the photosensitive composition to generate a region of the object; and repeating the illuminating step one or more additional times at one or more additional locations to generate one or more additional regions of the object. |
| FILED | Monday, November 01, 2021 |
| APPL NO | 17/515841 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/153 (20170801) Optical Elements, Systems, or Apparatus G02B 6/107 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0037 (20130101) G03F 7/70416 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220172122 | SHEN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intelligent Fusion Technology, Inc. (Germantown, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dan SHEN (Germantown, Maryland); Peter ZULCH (Rome, New York); Marcello DISASIO (Rome, New York); Erik BLASCH (Arlington, Virginia); Genshe CHEN (Germantown, Maryland) |
| ABSTRACT | The present disclosure provide a system, a method, and a storage medium for distributed joint manifold learning (DJML) based heterogeneous sensor data fusion. The system includes a plurality of nodes; and each node includes at least one camera; one or more sensors; at least one memory configured to store program instructions; and at least one processor, when executing the program instructions, configured to obtain heterogeneous sensor data from the one or more sensors to form a joint manifold; determine one or more optimum manifold learning algorithms by evaluating a plurality of manifold learning algorithms based on the joint manifold; compute a contribution of the node based on the one or more optimum manifold learning algorithms; update a contribution table based on the contribution of the node and contributions received from one or more neighboring nodes; and broadcast the updated contribution table to the one or more neighboring nodes. |
| FILED | Monday, December 27, 2021 |
| APPL NO | 17/563014 |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6289 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Original (OR) Class Pictorial Communication, e.g Television H04N 5/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220173303 | Boriskina et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Svetlana V. Boriskina (Winchester, Massachusetts); Bruno Lorenzi (Ponte San Pietro, Italy); Gang Chen (Carlisle, Massachusetts); Yoichiro Tsurimaki (Cambridge, Massachusetts) |
| ABSTRACT | Photo-detectors disclosed include at least one of a thin film or a heterostructure of photo-sensitive material and a pair of Ohmic contacts coupled to the at least one of the thin film or the heterostructure. The at least one of the thin film or the heterostructure is configured to be under a strain gradient to induce shift current flow within the material to perform photo-detection in a frequency range that includes a mid-infrared frequency range. The photo-detectors provided for can include a variety of configurations, such as a lateral configuration or a vertical configuration, and can operate in self-powered and negative illumination regimes. Associated methods are also provided, which can include inducing a strain gradient and performing photo-detection in a frequency range that includes a mid-infrared frequency range. |
| FILED | Tuesday, August 31, 2021 |
| APPL NO | 17/463483 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/1129 (20130101) H01L 41/113 (20130101) H01L 41/193 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220173307 | Sun et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nian-Xiang Sun (Winchester, Massachusetts); Nirjhar Bhattacharjee (Cambridge, Massachusetts) |
| ABSTRACT | A thin film heterostructure of a topological insulator (TI) with a normal metal (NM) is used as a highly energy efficient and low power dissipation spin Hall Material (SHM). The TI material is sputter deposited onto a substrate and cooled in high vacuum, and an NM material is sputter deposited onto the TI film. The structure and method is compatible with complementary metal oxide (CMOS) processes, and with growth of large-area TI films for wafer-level device fabrication. |
| FILED | Thursday, December 02, 2021 |
| APPL NO | 17/457348 |
| CURRENT CPC | Static Stores G11C 11/161 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/222 (20130101) H01L 43/04 (20130101) H01L 43/10 (20130101) H01L 43/14 (20130101) H01L 43/065 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220173366 | Skalny et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | Government of the United States, as represented by the Secretary of the Army (, None) |
| INVENTOR(S) | David Anthony Skalny (Shelby Township, Michigan); Craig William Schmehl (Royal Oak, Michigan) |
| ABSTRACT | A surrogate component for a test system is described. The surrogate component may comprise: a body, comprising, a first shell comprising a plurality of exit holes; and a second shell coupled to the first shell, wherein the second shell comprises a first connection interface and a second connection interface; and a wiring harness, comprising: at least one data communication line coupled to the first connection interface and passing through one of the plurality of exit holes; and at least one power line coupled to the second connection interface and passing through the one of the plurality of exit holes. |
| FILED | Wednesday, December 02, 2020 |
| APPL NO | 17/109432 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/06 (20130101) Original (OR) Class H01M 2/1077 (20130101) H01M 10/425 (20130101) H01M 2220/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220173565 | Keyser et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | US Gov't as represented by Sec'y of Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christian Keyser (Shalimar, Florida); Trevor Courtney (Niceville, Florida); John Timler (River Ridge, Louisiana); David M Barrett (Westminister, Maryland) |
| ABSTRACT | A cylindrical electrode module of a fiber optic laser system includes an inner cylinder having an inner repeating pattern of longitudinally-aligned positive and negative electrodes on an outer surface of the inner cylinder. The cylindrical electrode mode includes an outer cylinder that encloses the inner cylinder. The outer cylinder that has an outer repeating pattern of longitudinally-aligned negative and positive electrodes on an inner surface of the inner cylinder that are in corresponding and complementary, parallel alignment with the positive and negative electrodes of the inner repeating pattern on the outer surface of the inner cylinder. The cylindrical electrode module includes an optical fiber having an input end configured to align with and be optically coupled to a pump laser. The optical fiber is wrapped around the inner cylinder within the outer cylinder to form a cylindrical fiber assembly. The electrodes are activated to achieve quasi-phase matching. |
| FILED | Tuesday, February 15, 2022 |
| APPL NO | 17/671962 |
| CURRENT CPC | Manufacture, Shaping, or Supplementary Processes C03B 2203/16 (20130101) C03B 2203/42 (20130101) Optical Elements, Systems, or Apparatus G02B 6/0005 (20130101) G02B 6/02328 (20130101) G02B 6/4296 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0385 (20130101) Original (OR) Class H01S 5/1003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220173818 | Dybdal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert B. Dybdal (Palos Verdes Estates, California); Catherine A. Allen (Los Angeles, California); Lamont Cooper, JR. (Fullerton, California) |
| ABSTRACT | Apparatus and methods for monitoring interference in radio communication systems are provided. In certain embodiments, an interference monitor system for a ground terminal detects for interference based on a sum of the power levels of orthogonal polarizations of detected interference, thereby allowing the total and average peak interference power levels to be obtained independent of interference polarization. Further, the interference can be divided into frequency bins over the received signal bandwidth(s), thereby facilitating measurement of interference spectral characteristics. Multiple interference monitors can be included to detect interference over the full angular range over which potential interference has access as well as to determine an angular direction of the interference. |
| FILED | Tuesday, January 07, 2020 |
| APPL NO | 16/736099 |
| CURRENT CPC | Transmission H04B 7/18519 (20130101) H04B 17/345 (20150115) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220174101 | ETHIER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The MITRE Corporation (McLean, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Randall Paul Joseph ETHIER (Burke, Virginia); Gene Lee HARRISON (Leesburg, Virginia) |
| ABSTRACT | Disclosed herein are system, apparatus, method and/or computer program product embodiments for providing survivable calling and conferencing. An embodiment operates by providing, by a first server, a first sub-conference to a plurality of user devices over first lines. The first sub-conference is combined with a second sub-conference to form a collective conference of the plurality of user devices. The first server accesses the conference. A second server is configured to provide the second sub-conference of the collective conference to the plurality of user devices over second lines, the first and second lines being distinct from each other. The collective conference may provide resilient and reliable sharing of information among participants and may leverage dispersed elements or diverse links simultaneously without impediments of echoes, loops, or other impacts. |
| FILED | Tuesday, December 07, 2021 |
| APPL NO | 17/544510 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 65/80 (20130101) H04L 65/403 (20130101) Original (OR) Class H04L 65/1073 (20130101) H04L 65/1096 (20130101) H04L 65/4076 (20130101) H04L 67/10 (20130101) H04L 69/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220174607 | Bulsara et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Naval Information Warfare Center Pacific (San Diego, California) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (San Diego, California) |
| INVENTOR(S) | Adi Ratan Bulsara (San Diego, California); Bruno Ando (Catania, Italy); Salvatore Baglio (Catania, Italy); Vincenzo Marletta (Catania, Italy) |
| ABSTRACT | An autonomous sensor that includes a snap-through buckling beam, a proof mass, an ultra-low-power microcontroller unit, a wireless transmitter, a power management unit, and a power storage unit. The snap-through buckling beam produces mechanical energy. The proof mass is attached to the snap-through buckling beam. The proof mass transfers mechanical energy to two piezoelectric transducers that convert the mechanical energy into electrical energy and produce an output signal. The ultra-low-power microcontroller unit converts the output signal into output data. The wireless transmitter transfers the output data to an external device. The power management unit provides the electrical energy to the ultra-low-power microcontroller unit and the wireless transmitter. The power storage unit is rechargeable, stores electrical energy from the two piezoelectric transducers, and non-replaceable. The autonomous sensor simultaneously harvests energy and measures vibrations in an external environment. |
| FILED | Tuesday, December 01, 2020 |
| APPL NO | 17/108503 |
| CURRENT CPC | Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 7/08 (20130101) Wireless Communication Networks H04W 52/0229 (20130101) H04W 52/0254 (20130101) Original (OR) Class H04W 84/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220174809 | Radel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PHOENIX LLC (MONONA, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ross Radel (Brooklyn, Wisconsin); Dave Schneider (Colorado Springs, Colorado); Eli Moll (Madison, Wisconsin); David Ozburn (Reston, Virginia); Evan Sengbusch (Verona, Wisconsin); Logan Campbell (Madison, Wisconsin) |
| ABSTRACT | A first system for producing a high flux of neutrons for non-destructive testing includes a dense plasma focus device neutronically coupled to a subcritical or sub-prompt critical fission assembly. The dense plasma focus device is a source of initiating neutrons for the fission assembly, and the fission assembly is configured to multiply a number of the initiating neutrons via inducing fission. A second system for producing a high flux of neutrons includes a gas-target neutron generator neutronically coupled to a subcritical or sub-prompt critical fission assembly. The gas-target neutron generator is a source of initiating neutrons for the fission assembly, and the fission assembly is configured to multiply a number of the initiating neutrons via inducing fission. |
| FILED | Friday, August 13, 2021 |
| APPL NO | 17/401725 |
| CURRENT CPC | Nuclear Reactors G21C 1/30 (20130101) Conversion of Chemical Elements; Radioactive Sources G21G 4/02 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/06 (20130101) H05H 3/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20220167901 | PARK et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sung-Yun PARK (Ann Arbor, Michigan); Kyounghwan NA (Sunnyvale, California); Euisik YOON (Ypsilanti, Michigan) |
| ABSTRACT | A neural recording probe and interface, along with a method of assembly, with the neural recording probe being minimally invasive and having high-density, multi-channel microelectrodes. In one example, the neural probe includes a plurality of bumps projecting from a bottom surface of a terminal body. Each bump is electrically connected to a corresponding one of a plurality of electrodes. The plurality of bumps is bonded to a respective one of a plurality of area pads of the integrated circuit with an anisotropic conductive film such that each of the plurality of electrodes of the neural probe is electrically connected to a respective one of the active circuits of the integrated circuit. |
| FILED | Wednesday, December 01, 2021 |
| APPL NO | 17/540185 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/273 (20210101) A61B 5/293 (20210101) Original (OR) Class A61B 5/304 (20210101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 24/11 (20130101) H01L 24/13 (20130101) H01L 24/73 (20130101) H01L 24/81 (20130101) H01L 24/83 (20130101) H01L 24/92 (20130101) H01L 2224/8112 (20130101) H01L 2224/11462 (20130101) H01L 2224/13144 (20130101) H01L 2224/13155 (20130101) H01L 2224/73204 (20130101) H01L 2224/83851 (20130101) H01L 2224/92125 (20130101) Amplifiers H03F 3/45475 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168426 | MEJIA ONETO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | TAMBO, INC. (San Francisco, California); THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jose Manuel MEJIA ONETO (San Francisco, California); Nathan YEE (San Francisco, California); Maksim ROYZEN (San Francisco, California); Sangeetha SRINIVASAN (San Francisco, California); Ethan MILLER (San Francisco, California) |
| ABSTRACT | Cyclooctene conjugates of therapeutic or diagnostic agents have improved aqueous solubility and can release the agents upon contact with a tetrazine-containing biomaterial. The cyclooctene conjugates provide site-selective delivery of agents at the location of the tetrazine-containing biomaterial in a subject. The compositions and methods have applications in the treatment of various diseases or conditions including cancer, tumor growths, and bacterial infections. |
| FILED | Tuesday, December 14, 2021 |
| APPL NO | 17/550731 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 47/61 (20170801) A61K 47/542 (20170801) A61K 47/545 (20170801) Original (OR) Class A61K 49/0041 (20130101) A61K 49/0043 (20130101) A61K 49/0052 (20130101) A61K 49/0054 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168571 | Shah et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Nishal Pradeepkumar Shah (Stanford, California); Eduardo Jose Chichilnisky (Stanford, California) |
| ABSTRACT | Systems and methods for artificial sight in accordance with embodiments of the invention are illustrated. One embodiment includes a retinal prosthesis system including an external controller, a scene imager, an eye imager, an implanted controller, and a stimulation interface in communication with the implanted controller, where the stimulation interface is positioned to stimulate a plurality of retinal ganglion cells (RGCs) of the eye, where the external controller is configured to obtain image data describing a scene from the scene imager, obtain eye position data from the eye imager, determine a field of view (FOV) in the scene based on the eye position data; where the implanted controller is configured to obtain the FOV from the external controller, continuously select stimulation pulses from a dictionary based on the FOV, and stimulate the plurality of RGCs using the stimulation interface in accordance with the selected stimulation pulses. |
| FILED | Monday, March 23, 2020 |
| APPL NO | 17/441261 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/08 (20130101) A61N 1/025 (20130101) A61N 1/0543 (20130101) A61N 1/36046 (20130101) Original (OR) Class A61N 1/37235 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168707 | Schlenoff et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INCORPORATED (Tallahassee, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph Schlenoff (Tallahassee, Florida); John Akintola (Tallahassee, Florida) |
| ABSTRACT | Described herein are articles comprising an anhydrous polyelectrolyte complex comprising an interpenetrating network of at least one positively charged polyelectrolyte polymer and at least one negatively charged polyelectrolyte polymer. The articles described herein are effective drying agents with respect to removing water from solvents and gasses. Also described herein are methods for making and using the articles described herein. |
| FILED | Thursday, December 02, 2021 |
| APPL NO | 17/457370 |
| CURRENT CPC | Separation B01D 17/0202 (20130101) B01D 19/0073 (20130101) B01D 2252/20 (20130101) B01D 2252/60 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/267 (20130101) Original (OR) Class Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/246 (20130101) C08J 2325/06 (20130101) C08J 2339/04 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/30 (20130101) C08K 3/34 (20130101) C08K 2003/3045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169256 | Beal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Craig E. Beal (Lewisburg, Pennsylvania); Sean N. Brennan (State College, Pennsylvania) |
| ABSTRACT | A device for estimating a friction coefficient between a road surface and an automotive tire through determination of a steering torque during a steering maneuver of a slow-rolling or stationary vehicle includes a computer configured for constructing a brush model for a description of the steering torque across a contact patch between the tire and road surface. The steering torque is a torque acting on a steering axis required to overcome resistance to tire twisting on the road surface at a wheel velocity and a steering rate. The steering torque depends on a tire brush vertical load distribution and relative motion of tire brushes and the road surface. The device further includes sensors for measuring the wheel velocity and the steering rate and mechanism for measurements or estimation of the steering torque. The friction coefficient is estimated based on the measurements or estimation of the steering torque and the brush model. |
| FILED | Thursday, March 26, 2020 |
| APPL NO | 17/441787 |
| CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 40/13 (20130101) B60W 40/068 (20130101) Original (OR) Class B60W 40/101 (20130101) B60W 2040/1384 (20130101) B60W 2420/10 (20130101) B60W 2510/202 (20130101) B60W 2520/28 (20130101) B60W 2540/18 (20130101) B60W 2552/40 (20200201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169363 | DI LUCA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matteo DI LUCA (Providence, Rhode Island); Kenneth BREUER (Newton, Massachusetts) |
| ABSTRACT | A free-streamline airfoil includes a front portion, the front portion including a leading edge geometry configured to force a sudden separation of the flow, and a contoured rear portion. |
| FILED | Monday, December 27, 2021 |
| APPL NO | 17/562752 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 3/14 (20130101) Original (OR) Class B64C 9/04 (20130101) B64C 23/00 (20130101) B64C 23/02 (20130101) B64C 23/005 (20130101) B64C 2003/146 (20130101) B64C 2230/04 (20130101) B64C 2230/08 (20130101) B64C 2230/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169543 | VECCHIARELLI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | PAUL VECCHIARELLI (LEXINGTON, South Carolina); JAMIE R. LEAD (COLUMBIA, South Carolina) |
| ABSTRACT | Described herein is a flow-through application and system that utilizes a nanoparticle technology, which is modular and scalable, that can be utilized to recover a contaminant from water using an attendant pump and in-line sensors along with magnets and ultrasonic energy to separate magnetic nanoparticles from an aqueous mixture and to further separate recovered contaminant from contaminant-adsorbent nanoparticles. The contaminant can include an organic contaminant, such as an oil. |
| FILED | Friday, October 01, 2021 |
| APPL NO | 17/492281 |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/36 (20130101) C02F 1/285 (20130101) C02F 1/288 (20130101) C02F 1/482 (20130101) C02F 1/485 (20130101) Original (OR) Class C02F 2103/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169684 | KLAPOETKE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Governors of the University of Alberta (Edmonton, Canada) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Governors of the University of Alberta (Edmonton, Canada) |
| INVENTOR(S) | Nathan KLAPOETKE (Ashburn, Virginia); Brian Yichiun CHOW (Cherry Hill, New Jersey); Edward BOYDEN (Chestnut Hill, Massachusetts); Gane KA-Shu WONG (Edmonton, Canada); Yongku Peter CHO (Vernon, Connecticut) |
| ABSTRACT | The invention, in some aspects relates to compositions and methods for altering cell activity and function and the introduction and use of light-activated ion channels. |
| FILED | Thursday, February 10, 2022 |
| APPL NO | 17/668766 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 41/0023 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) Peptides C07K 14/405 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5041 (20130101) G01N 33/5058 (20130101) G01N 33/48728 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169965 | Kamm et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Roger Dale Kamm (Cambridge, Massachusetts); Tatsuya Osaki (Cambridge, Massachusetts) |
| ABSTRACT | Microfluidic devices with neuronal cells, muscle cells, and optionally other cell types co-cultured therein are provided. Typically one or more the cells has a mutation that contributes to or causes a neuronal or muscular disease or disorder. For example, in some embodiments, one or more of the cultured cells are derived from a subject with a neuronal or muscular disease or disorder. The microfluidic device can facilitate formation of a 3D motor unit and a neuromuscular junction in vitro, and be used to monitor the molecular, biochemical, cellular, and morphological differences in the formation of such structures by healthy and diseased cells, and for testing compounds, dosages of compounds, dosing regimes, and combinations thereof, that may improve or worsen their formation. An exemplary combination drug therapy identified in this way is also provided. |
| FILED | Tuesday, April 09, 2019 |
| APPL NO | 17/602655 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/436 (20130101) A61K 31/496 (20130101) A61K 31/4706 (20130101) A61K 45/06 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/04 (20130101) C12M 23/16 (20130101) Original (OR) Class C12M 23/34 (20130101) C12M 33/04 (20130101) C12M 41/40 (20130101) C12M 41/48 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5058 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220170009 | Batey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado, A Body Corporate (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert T. Batey (Boulder, Colorado); Ely B. Porter (Boxborough, Massachusetts) |
| ABSTRACT | Provided herein are libraries of scaffolds derived from riboswitches and small ribozymes and their methods of use. The scaffolds of the invention yield aptamers that are easily identified and characterized by virtue of the structural scaffold. The nature of the scaffold predisposes these RNAs for coupling to readout domains to engineer biosensors that function in vitro and in vivo. Biosensors, synthetic RNA agents and synthetic DNA agents, and their methods of use, are also provided. |
| FILED | Thursday, December 02, 2021 |
| APPL NO | 17/541068 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) C12N 15/1093 (20130101) Original (OR) Class C12N 2310/16 (20130101) C12N 2310/531 (20130101) C12N 2330/31 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220170087 | Tung et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Steve TUNG (Fayetteville, Arkansas); Bo MA (Fayetteville, Arkansas); Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steve Tung (Fayetteville, Arkansas); Bo Ma (Fayetteville, Arkansas) |
| ABSTRACT | A method of DNA base-calling from a nanochannel DNA sequencer. The method includes building a reference map and preparing an unknown sequence of DNA prior to the final step of data matching. The reference map includes a series of reference characters, such as numbers, that describe the change in tunneling current of a DNA strand with a known sequence. A DNA strand of unknown sequence is prepared so that the change in electrical measurement can also be described numerically. The section of match between the DNA strand of unknown sequence and the reference map is used to determine the sequence of the DNA strand. |
| FILED | Wednesday, March 18, 2020 |
| APPL NO | 17/441094 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/04 (20130101) G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220170117 | Lucks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Julius B. Lucks (Evanston, Illinois); Walter M. Thavarajah (Chicago, Illinois); Adam D. Silverman (Chicago, Illinois); Michael C. Jewett (Evanston, Illinois) |
| ABSTRACT | Disclosed are methods and systems for detecting fluoride as a target molecule in a test sample which utilize a cell-protein synthesis (CFPS) reaction and an engineered fluoride-sensing riboswitch. The components used in the disclosed methods and systems may be dried or lyophilized and may be present or immobilized on a paper substrate. |
| FILED | Tuesday, March 03, 2020 |
| APPL NO | 17/593026 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) C12N 2310/16 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6897 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/78 (20130101) G01N 33/84 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220171000 | Shalaev et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Vladimir M. Shalaev (West Lafayette, Indiana); Pramey Upadhyaya (West Lafayette, Indiana); Abhishek Bharatbhai Solanki (West Lafayette, Indiana); Simeon I. Bogdanov (Champaign, Illinois); Yong P. Chen (West Lafayette, Indiana); Mohammad Mushfiqur Rahman (West Lafayette, Indiana); Avinash Rustagi (West Lafayette, Indiana) |
| ABSTRACT | A nanodevice provides for electric-field control of magnon-QSD interactions. The nanodevice includes a ferroelectric substrate, a ferromagnetic material disposed over the ferroelectric substrate, and a nanodiamond including an ensemble of nitrogen-vacancy (NV) spins, each NV magnetically interfacing with the ferromagnetic material. An electric field is measured by applying a voltage across the ferroelectric substrate and the ferromagnetic material, changing a magnon excitation spectrum of the ferromagnetic material with respect to an electron spin resonance frequency of the ensemble of NV spins, and measuring a relaxation rate of the ensemble of NV spins. |
| FILED | Tuesday, November 30, 2021 |
| APPL NO | 17/538007 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/02 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/02 (20130101) H01L 43/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220171013 | KASSAS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Zak KASSAS (Irvine, California); Joe KHALIFE (Irvine, California); Ali ABDALLAH (Irvine, California) |
| ABSTRACT | System and device configurations, and processes are provided for determining position based on low Earth orbit (LEO) satellite signals. Frameworks described herein can include performing Doppler frequency measurement for received quadrature phase shift keying (QPSK) signals. The framework may include channel tracking operations to determine Doppler shift measurements, a navigation filter operation to determine clock drift based on each Doppler shift measurement from each channel tracking loop, and determining position of a device based on LEO satellite signal sources. Frameworks described herein are also provided for carrier phase differential (CD)—low Earth orbit (LEO) (CD-LEO) measurements that may utilize a base and a rover without requiring prior knowledge of rover position. Embodiments can also cancel effects of ionospheric and tropospheric delays on the carrier phase and CD-LEO measurements. |
| FILED | Wednesday, April 15, 2020 |
| APPL NO | 17/604154 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/009 (20130101) G01S 5/0246 (20200501) G01S 5/0284 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220171077 | KASSAS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Zak KASSAS (Irvine, California); Josh MORALES (Irvine, California); Joe KHALIFE (Irvine, California) |
| ABSTRACT | Systems, device configurations, and processes are provided for tracking and navigation using low-earth orbit satellite (LEO) signals. Embodiments are provided to track LEO satellites in the absence or during interrupted service by global position sources (e.g., GNSS). Operations and a framework are provided to use low-earth orbit (LEO) downlink transmissions as a source of positioning data. Operations can include performing a Doppler frequency measurement on received satellite downlink transmissions to determine a pseudorange rate measurement for a vehicle relative to at least one LEO satellite. Pseudorange rate measurements may be used to correct vehicle position data of a vehicles inertial navigation system (INS) and for control/navigation of the vehicle. Embodiments allow for simultaneous tracking of LEO satellites and navigation of a vehicle, such as an unmanned aerial vehicle. Embodiments are also directed to employing a propagation model for LEO position and velocity within a simultaneous tracking and navigation (STAN) framework. |
| FILED | Wednesday, April 15, 2020 |
| APPL NO | 17/604157 |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/165 (20130101) G01C 21/188 (20200801) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/49 (20130101) Original (OR) Class G01S 19/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220171861 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Fayetteville, Arkansas) |
| ASSIGNEE(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Fayetteville, Arkansas) |
| INVENTOR(S) | Qinghua Li (Fayetteville, Arkansas); Fengli Zhang (Fayetteville, Arkansas) |
| ABSTRACT | A program that defines and assesses the dynamic risk of software vulnerabilities and considers the dynamic risks into patch scheduling to reduce security risks posed by vulnerabilities and provide formal guidance to security operations at various organizations. |
| FILED | Wednesday, December 01, 2021 |
| APPL NO | 17/539937 |
| CURRENT CPC | Electric Digital Data Processing G06F 8/65 (20130101) G06F 21/577 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220172356 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
| ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
| INVENTOR(S) | Tianbao Yang (Iowa City, Iowa); Zhuoning Yuan (Iowa City, Iowa); Yan Yan (Pullman, Washington); Qi Qi (Coralville, Iowa) |
| ABSTRACT | A computer-based automated method of performing classification includes learning a deep neural network by maximizing an area under a receiver operating characteristic curve (AUC) or precision-recall curve (AUPRC) score wherein a margin-based surrogate loss function is applied, receiving an input into a deep neural network, and processing the input to the deep neural network to generate a prediction, wherein the prediction comprises a classification of the input. The computer-based automated method may be performed by executing instructions in at least one processor, and wherein said instructions are stored on a non-transitory memory readable by the at least one processor. |
| FILED | Thursday, December 02, 2021 |
| APPL NO | 17/540472 |
| CURRENT CPC | Electric Digital Data Processing G06F 17/18 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 2207/10116 (20130101) Image or Video Recognition or Understanding G06V 10/30 (20220101) G06V 10/82 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220172594 | CHO |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yong CHO (Atlanta, Georgia) |
| ABSTRACT | An exemplary method and system is disclosed that facilitates the monitoring of worker's productivity and safety, for example, at a construction site and other like labor-intensive occupation and settings. The exemplary method and system provides wearable-based motion sensing and/or proximity sensing between worker and construction equipment. A study discussed herein suggests that sensing at two or more torso locations can provide 95% accuracy in classifying worker's action or motion at a construction site. In some embodiments, as discussed herein, the acquired sensed data are transmitted, over a mesh network, e.g., established between the wearable devices, to a cloud infrastructure to facilitate the real-time monitoring of action and actions that such sites. |
| FILED | Wednesday, March 18, 2020 |
| APPL NO | 17/440250 |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 1/002 (20130101) Safety Devices in General; F16P 3/147 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 11/06 (20130101) Computer Systems Based on Specific Computational Models G06N 3/0445 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/06398 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 7/06 (20130101) G08B 21/0446 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220172847 | Shinozaki |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gen Shinozaki (Iowa City, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gen Shinozaki (Iowa City, Iowa) |
| ABSTRACT | The disclosed apparatus, systems and methods relate to predicting, screening, and monitoring for mortality and other negative patient outcomes. Systems and methods may include receiving one or more signals from one or more sensing devices; processing the one or more signals to extract one or more features from the one or more signals; analyzing the one or more features to determine one or more values for each of the one or more features; comparing at least one of the one or more values or a measure based on at least one of the one or more values to a threshold; determining a presence, absence, or likelihood of the subsequent mortality, falls or extended hospital stays for a patient based on the comparison; and outputting an indication of the presence, absence, or likelihood of the subsequent development of poor outcomes or death for the patient. |
| FILED | Monday, April 06, 2020 |
| APPL NO | 17/601344 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/165 (20130101) A61B 5/374 (20210101) A61B 5/384 (20210101) A61B 5/7275 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/30 (20180101) Original (OR) Class G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20220168781 | Kumar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sortera Alloys, Inc. (Forth Worth, Texas) |
| ASSIGNEE(S) | Sortera Alloys, Inc. (Forth Worth, Texas) |
| INVENTOR(S) | Nalin Kumar (Fort Worth, Texas); Manuel Gerardo Garcia, JR. (Lexington, Kentucky) |
| ABSTRACT | A material sorting system sorts materials utilizing multiple stages of classification and sorting, including a vision system that implements a machine learning system in order to identify or classify each of the materials, and Laser Induced Breakdown Spectroscopy to perform a subsequent classification and sorting of the remaining materials. |
| FILED | Wednesday, February 16, 2022 |
| APPL NO | 17/673694 |
| CURRENT CPC | Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 5/04 (20130101) B07C 5/34 (20130101) B07C 5/342 (20130101) B07C 5/3422 (20130101) Original (OR) Class B07C 2501/0054 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168814 | DUDUKOVIC et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nikola DUDUKOVIC (Hayward, California); Alexander BAKER (Livermore, California); Joshua R. DEOTTE (Livermore, California); Eric B. DUOSS (Danville, California); Scott MCCALL (Livermore, California) |
| ABSTRACT | The present disclosure relates to an additive manufacturing system. The system incorporates a nozzle in communication with a quantity of feedstock material including granular metal powder particles. The nozzle is configured to deposit the granular metal powder particles on at least one of a build plate or a previously formed material layer, to form at least one layer of a part. The system also incorporates a magnetic field generator subsystem for producing a magnetic field configured to orient the granular metal powder particles in a desired orientation before fusing of the granular metal powder particles occurs. |
| FILED | Monday, November 30, 2020 |
| APPL NO | 17/106251 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/28 (20210101) B22F 10/38 (20210101) Original (OR) Class B22F 10/85 (20210101) B22F 12/30 (20210101) B22F 12/53 (20210101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168947 | Zekriardehani et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Eaton Intelligent Power Limited (Dublin, Ireland) |
| ASSIGNEE(S) | Eaton Intelligent Power Limited (Dublin, Ireland) |
| INVENTOR(S) | Shahab Zekriardehani (Farmington Hills, Michigan); Jeremy M. Santiago Baerga (Southfield, Michigan); Javed Abdurrazzaq Mapkar (Northville, Michigan) |
| ABSTRACT | The present disclosure relates to fused filament fabrication and thermally conductive polymers used therein. Also described are processes for forming an article using fused filament fabrication techniques. |
| FILED | Tuesday, November 30, 2021 |
| APPL NO | 17/456978 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/118 (20170801) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/042 (20170501) C08K 7/18 (20130101) C08K 2201/001 (20130101) Compositions of Macromolecular Compounds C08L 77/06 (20130101) C08L 81/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220168950 | Yu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Wenhua Yu (Darien, Illinois); Dileep Singh (Naperville, Illinois); David M. France (Lombard, Illinois); Wenchao Du (Willowbrook, Illinois) |
| ABSTRACT | A method of depowdering objects (e.g., heat exchangers) having small and/or complex internal geometries and manufactured using an additive manufacturing technique performed with a powder material. The method includes applying a pressurized fluid to the objects via a pressurized fluid applicator operatively coupled to the object, thereby removing a portion of unbound powder material on or in the object. The method further includes applying vortex vibration to the object via a vortex vibration source operatively coupled to the object, thereby loosening a portion of the unbound powder material remaining on or in the object, and applying the pressurized fluid to the object via the pressurized fluid application, thereby removing a portion of the loosened, unbound powder material from the object. The latter two applying steps are repeated until a specified amount of the unbound powder material has been removed from the object. |
| FILED | Monday, November 30, 2020 |
| APPL NO | 17/107726 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/35 (20170801) B29C 64/165 (20170801) Original (OR) Class B29C 64/245 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169764 | Hartmann-Thompson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | 3M INNOVATIVE PROPERTIES COMPANY (St. Paul, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Claire Hartmann-Thompson (Lake Elmo, Minnesota); Mark J. Pellerite (Woodbury, Minnesota); Marina M. Kaplun (Woodbury, Minnesota); John C. Thomas (St. Paul, Minnesota) |
| ABSTRACT | Cationic copolymers having pendant N-allylimidazolium-containing groups are provided. The cationic copolymers can be used, for example, to provide anion exchange membranes for use in electrochemical cells such as fuel cells, electrolyzers, batteries, and electrodialysis cells. The anion exchange membranes typically have good mechanical properties and ionic conductivity. |
| FILED | Monday, May 18, 2020 |
| APPL NO | 17/593703 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 41/14 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 212/08 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 50/414 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169866 | Zekriardehani et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Eaton Intelligent Power Limited (Dublin, Ireland) |
| ASSIGNEE(S) | Eaton Intelligent Power Limited (Dublin, Ireland) |
| INVENTOR(S) | Shahab Zekriardehani (Farmington Hills, Michigan); Jeremy M. Santiago Baerga (Southfield, Michigan); Javed Abdurrazzaq Mapkar (Northville, Michigan); John Trublowski (Troy, Michigan) |
| ABSTRACT | The present disclosure relates to selective laser sintering printing and thermally conductive polymers used therein. Also described are processes for forming an article using selective laser sintering techniques. |
| FILED | Tuesday, November 30, 2021 |
| APPL NO | 17/538341 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/153 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 70/00 (20141201) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/031 (20130101) Original (OR) Class C09D 123/00 (20130101) C09D 161/00 (20130101) C09D 177/02 (20130101) C09D 177/06 (20130101) C09D 181/02 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 5/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169908 | PHILLIPS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MONTANA STATE UNIVERSITY (Bozeman, Montana); MONTANA EMERGENT TECHNOLOGIES, INC. (Butte, Montana) |
| ASSIGNEE(S) | MONTANA STATE UNIVERSITY (Bozeman, Montana); MONTANA EMERGENT TECHNOLOGIES, INC. (Butte, Montana) |
| INVENTOR(S) | Adrienne J. PHILLIPS (Bozeman, Montana); Robin GERLACH (Bozeman, Montana); Alfred B. CUNNINGHAM (Bozeman, Montana); Lee H. SPANGLER (Bozeman, Montana); Arda AKYEL (Bozeman, Montana); Catherrin M. KIRKLAND (Bozeman, Montana); Dwight Randall HIEBERT (Butte, Montana) |
| ABSTRACT | Methods of conducting ureolysis-induced calcium carbonate precipitation with a heat-treated cell preparation, methods for preparing the heat-treated cell preparation, and related materials. The methods of conducting ureolysis-induced calcium carbonate precipitation include precipitating calcium carbonate at a location by introducing urea, calcium, and a heat-treated cell preparation comprising active urease enzyme to the location. The urease enzyme hydrolyzes the urea to ammonium carbonate, and the calcium reacts with the carbonate to form a calcium carbonate precipitate at the location. The methods of preparing the heat-treated cell preparation include heating a urease-producing cell preparation at a temperature and for a time sufficient to inactivate at least a portion of the cells in the urease-producing cell preparation while maintaining at least some urease activity of urease made by the cells in the urease-producing cell preparation |
| FILED | Wednesday, March 25, 2020 |
| APPL NO | 17/441336 |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 28/10 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 8/42 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/58 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220170053 | Xu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NATIONAL TECHNOLOGY and ENGINEERING SOLUTIONS OF SANDIA, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Feng Xu (Albany, California); Blake Simmons (San Francisco, California); Seema Singh (Clarksburg, Maryland) |
| ABSTRACT | In one aspect, the present invention provides methods for preparing a fermentation product. The methods include pre-treating a mixture of biomass and ionic liquid, wherein the ionic liquid comprises a choline cation and the biomass comprises polysaccharide and lignin. The methods further include forming hydrolysates from the introduction of glycoside hydrolase to the pre-treated mixture at conditions sufficient to produce a sugar composition mixture for fermentation steps. The present invention provides methods for loading biomass mixtures in a batch-fed process, wherein the biomass slurries can be loaded into water or a concentrated sugar composition for hydrolysate production. The methods can be performed in a one-pot process, wherein the ionic liquids are present in the mixtures throughout each step. Aspects of the invention provide compositions of sugar composition mixtures and fermentation product mixtures. |
| FILED | Monday, September 13, 2021 |
| APPL NO | 17/473906 |
| CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/10 (20130101) Original (OR) Class C12P 19/02 (20130101) C12P 19/14 (20130101) C12P 2201/00 (20130101) C12P 2203/00 (20130101) Saccharides Obtained From Natural Sources or by Hydrolysis of Naturally Occurring Disaccharides, Oligosaccharides or Polysaccharides C13K 1/02 (20130101) C13K 13/002 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220170877 | HORWOOD et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Corie HORWOOD (Livermore, California); Michael STADERMANN (Pleasanton, California) |
| ABSTRACT | The present disclosure relates to a method for forming a reference electrode for use in electrochemical testing applications. The method may involve positioning a porous frit against one end of a hollow tube, and securing the frit and the hollow tube to one another to form an assembly. The method may further involve forming a silver sulfide coating on a silver wire to produce a silver sulfide coated silver wire. The method may further involve filling the hollow tube with a non-aqueous solution, and inserting at least a portion of the silver sulfide coated silver wire into the non-aqueous solution in the hollow tube. |
| FILED | Wednesday, February 16, 2022 |
| APPL NO | 17/673371 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/0623 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/301 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220171861 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Fayetteville, Arkansas) |
| ASSIGNEE(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Fayetteville, Arkansas) |
| INVENTOR(S) | Qinghua Li (Fayetteville, Arkansas); Fengli Zhang (Fayetteville, Arkansas) |
| ABSTRACT | A program that defines and assesses the dynamic risk of software vulnerabilities and considers the dynamic risks into patch scheduling to reduce security risks posed by vulnerabilities and provide formal guidance to security operations at various organizations. |
| FILED | Wednesday, December 01, 2021 |
| APPL NO | 17/539937 |
| CURRENT CPC | Electric Digital Data Processing G06F 8/65 (20130101) G06F 21/577 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220172852 | LEVINSKY |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania) |
| ASSIGNEE(S) | Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania) |
| INVENTOR(S) | Alex LEVINSKY (Pittsburgh, Pennsylvania) |
| ABSTRACT | A reactor unit cell is disclosed including a graphite moderator structure, a heat pipe positioned in the graphite moderator structure, and a fuel assembly positioned in the graphite moderator structure. The fuel assembly comprises a beryllium-oxide sleeve and nuclear fuel positioned in the beryllium-oxide sleeve. |
| FILED | Tuesday, December 01, 2020 |
| APPL NO | 17/108602 |
| CURRENT CPC | Nuclear Reactors G21C 3/07 (20130101) G21C 15/257 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220173384 | YUSHIN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sila Nanotechnologies Inc. (Alameda, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gleb YUSHIN (Atlanta, Georgia); Bogdan ZDYRKO (Atlanta, Georgia); Addison SHELTON (Atlanta, Georgia); Eugene BERDICHEVSKY (Alameda, California); Igor LUZINOV (Clemson, South Carolina); Alexander JACOBS (Oakland, California); Eerik HANTSOO (Oakland, California); George GOMES (Alameda, California) |
| ABSTRACT | A battery electrode composition is provided comprising composite particles, with each composite particle comprising active material and a scaffolding matrix. The active material is provided to store and release ions during battery operation. For certain active materials of interest, the storing and releasing of the ions causes a substantial change in volume of the active material. The scaffolding matrix is provided as a porous, electrically-conductive scaffolding matrix within which the active material is disposed. In this way, the scaffolding matrix structurally supports the active material, electrically interconnects the active material, and accommodates the changes in volume of the active material. |
| FILED | Wednesday, February 09, 2022 |
| APPL NO | 17/667965 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/13 (20130101) H01M 4/38 (20130101) H01M 4/139 (20130101) H01M 4/364 (20130101) Original (OR) Class H01M 4/366 (20130101) H01M 4/0402 (20130101) H01M 4/624 (20130101) H01M 4/625 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220173396 | WANG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Donghai WANG (University Park, Pennsylvania); Tom MALLOUK (University Park, Pennsylvania); Yue GAO (University Park, Pennsylvania); THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Donghai WANG (University Park, Pennsylvania); Tom MALLOUK (University Park, Pennsylvania); Yue GAO (University Park, Pennsylvania) |
| ABSTRACT | Disclosed is a reactive polymer composite comprising a reactive functionalized polymer having a main polymer chain with functionalization along the main polymer chain, wherein the functionalization comprises one or more functional groups that are configured to react with a metal electrode to form a polymeric metal salt and one, or more functional groups configured to electrochemically decompose. Also disclosed are electrodes and batteries comprising the same. Also disclosed are methods of making the same. |
| FILED | Monday, March 09, 2020 |
| APPL NO | 17/437202 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/382 (20130101) H01M 4/602 (20130101) Original (OR) Class H01M 4/8668 (20130101) H01M 10/44 (20130101) H01M 10/0525 (20130101) H01M 10/0562 (20130101) H01M 2300/0065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220173567 | Sipes, JR. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | OPTICAL ENGINES, INC. (Colorado Springs, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Donald Lee Sipes, JR. (Colorado Springs, Colorado); Jason Tafoya (Colorado Springs, Colorado); Brian Michael Schulz (Colorado Springs, Colorado); James Lefort (Colorado Springs, Colorado); Daniel Scott Schulz (Colorado Springs, Colorado) |
| ABSTRACT | A fiber support assembly includes: a first glass tube, wherein the first glass tube is at tached to a microlens or lenslet of a microlens or lenslet array; a second glass tube at least partially disposed within the first glass tube; and a gain fiber disposed within the second glass tube, wherein the gain fiber has a first tapered end cap, and wherein the gain fiber with the first tapered end cap is aligned to the microlens or lenslet attached to the first glass tube. The fiber support assembly may further include: a pump fiber disposed within the second glass tube, wherein the pump fiber has a second tapered end cap; and a reflector configured to receive counter-pumping light from the pump fiber and direct the counter-pumping light to the first tapered end cap of the gain fiber. |
| FILED | Friday, January 14, 2022 |
| APPL NO | 17/576431 |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/06745 (20130101) H01S 3/094019 (20130101) Original (OR) Class H01S 3/094053 (20130101) H01S 3/094057 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20220167613 | Reifenrath |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stratacor, Inc. (Novato, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | William Reifenrath (Novato, California) |
| ABSTRACT | This disclosure provides insect or arthropod pesticidal compositions of mono alpha carboxylic acids or esters thereof in combination with an emulsifier, an adjuvant comprising choline, and a carrier. Also provided are aqueous concentrates comprising the pesticidal compositions, as well as aqueous dilutions of the aqueous concentrates. Also provided are methods of killing or incapacitating insects or arthropods and methods of treating cattle to protect against biting insects or arthropods using such compositions. |
| FILED | Friday, October 01, 2021 |
| APPL NO | 17/492317 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 33/12 (20130101) Original (OR) Class A01N 37/02 (20130101) Biocidal, Pest Repellant, Pest Attractant or Plant Growth Regulatory Activity of Chemical Compounds or Preparations A01P 7/04 (20210801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220167629 | MEHTA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CORN PRODUCTS DEVELOPMENT, INC. (WESTCHESTER, Illinois); UNITED STATES DEPARTMENT OF AGRICULTURE (Beltsville, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pushpak MEHTA (Bridgewater, New Jersey); Mark MACRANDER (Bridgewater, New Jersey); Peter COTTY (Beltsville, Maryland) |
| ABSTRACT | Disclosed herein is an aflatoxin biocontrol composition comprising corn germ as a nutrient carrier and an atoxigenic Aspergillus strain. Also disclosed herein are methods of making and using such compositions. |
| FILED | Monday, March 30, 2020 |
| APPL NO | 17/441099 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/34 (20200101) Original (OR) Class Biocidal, Pest Repellant, Pest Attractant or Plant Growth Regulatory Activity of Chemical Compounds or Preparations A01P 3/00 (20210801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220170052 | Steele et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James L. Steele (Madison, Wisconsin); Jeffrey Broadbent (Logan, Utah); Ekkarat Phrommao (Madison, Wisconsin) |
| ABSTRACT | An ethanologen for producing biofuel from one or more carbohydrates and reducing lactate and acetate production in a biofuel manufacturing process. The ethanologen is made by introducing into the ethanologen one or more exogenous genes required for production of a bacteriocin. The resulting ethanologen reduces lactate and acetate production by contaminant lactic acid bacteria by expression of the bacteriocin during the biofuel manufacturing process. Certain resulting ethanologens ferment sugars not naturally or not preferentially utilized by Saccharomyces cerevisiae during the manufacturing process |
| FILED | Thursday, December 16, 2021 |
| APPL NO | 17/553279 |
| CURRENT CPC | Peptides C07K 14/195 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/16 (20130101) C12N 1/20 (20130101) C12N 1/38 (20130101) C12N 9/88 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/06 (20130101) C12P 7/10 (20130101) C12P 7/065 (20130101) Original (OR) Class C12P 7/649 (20130101) C12P 21/02 (20130101) Enzymes C12Y 101/01001 (20130101) C12Y 401/01001 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/10 (20130101) Y02E 50/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20220168970 | Palmieri et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U. S. A. as represented by the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Frank L. Palmieri (Yorktown, Virginia); John W. Connell (Yorktown, Virginia); Robetro J. Cano (Yorktown, Virginia); Tyler B. Hudson (Suffolk, Virginia) |
| ABSTRACT | Described herein are composites produced with a barrier ply. The barrier-ply prevents excessive mixing between conventional composite precursors and stoichiometrically-offset precursors during a cure process by gelling early in the cure cycle before extensive mixing can occur. Excess mixing requires the use of thicker offset resin layers with a large stoichiometric offset, which may limit the performance of unitized structures. The use of the barrier plies described herein address this issue and improves the mechanical properties of the final composite product as well as the efficiency for making the composites. |
| FILED | Wednesday, December 01, 2021 |
| APPL NO | 17/539556 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 70/30 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2063/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220171848 | Srivastava et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of South Carolina (Columbia, South Carolina) |
| ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
| INVENTOR(S) | Biplav Srivastava (Chapin, South Carolina); Ying Meng (Columbia, South Carolina); Jianhai Su (West Columbia, South Carolina); Pooyan Jamshidi Dermani (Columbia, South Carolina); Jason M. O'Kane (Columbia, South Carolina) |
| ABSTRACT | A method and device for synthesizing adaptive defenses of artificial intelligence (AI) systems against adversarial attacks. The method comprises, during a design phase, creating a library of weak defenses (WDs); preprocessing the WDs in the library; selecting a subset W of WDs from the WDs in the library; and, during a deployment phase, synthesizing an ensemble strategy based on an input of the selected subset W of WDs, the ensemble strategy used as a defense against adversarial attacks. |
| FILED | Tuesday, September 28, 2021 |
| APPL NO | 17/487502 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/552 (20130101) Original (OR) Class G06F 2221/034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220173955 | Barsoum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Constellation Designs, LLC (Anaheim, California) |
| ASSIGNEE(S) | Constellation Designs, LLC (Anaheim, California) |
| INVENTOR(S) | Maged F. Barsoum (San Jose, California); Christopher R. Jones (Pacific Palisades, California) |
| ABSTRACT | Communication systems are described that use signal constellations, which have unequally spaced (i.e. ‘geometrically’ shaped) points. In many embodiments, the communication systems use specific geometric constellations that are capacity optimized at a specific SNR. In addition, ranges within which the constellation points of a capacity optimized constellation can be perturbed and are still likely to achieve a given percentage of the optimal capacity increase compared to a constellation that maximizes dmin, are also described. Capacity measures that are used in the selection of the location of constellation points include, but are not limited to, parallel decode (PD) capacity and joint capacity. |
| FILED | Monday, May 24, 2021 |
| APPL NO | 17/328993 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/12 (20130101) A61B 6/503 (20130101) A61B 6/527 (20130101) A61B 6/5235 (20130101) A61B 6/5264 (20130101) A61B 34/20 (20160201) A61B 2017/00703 (20130101) Image Data Processing or Generation, in General G06T 7/33 (20170101) Transmission H04B 14/023 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) H04L 27/3405 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 20220167913 | Reed et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | David A. Reed (Baltimore, Maryland); George C. Emmett (Wilmington, Delaware) |
| ABSTRACT | In an example, a method of detecting cyanide exposure of an individual comprises measuring a thiocyanate level of the individual, and comparing the measured thiocyanate level to a preset thiocyanate threshold to determine whether the measured thiocyanate level is above the preset thiocyanate threshold indicating a level of cyanide poisoning requiring immediate medical assessment. |
| FILED | Tuesday, February 15, 2022 |
| APPL NO | 17/671925 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/4845 (20130101) Original (OR) Class A61B 5/14551 (20130101) A61B 10/0051 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220170972 | Karns et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Columbus, Ohio) |
| ASSIGNEE(S) | Battelle Memorial Institute (Columbus, Ohio) |
| INVENTOR(S) | Duane Karns (Mays Landing, New Jersey); James Weatherall (Linwood, New Jersey); Jeffrey Barber (Vineland, New Jersey); Barry Smith (Galloway, New Jersey) |
| ABSTRACT | An automated resonant waveguide cavity system for determining one or complex permittivity measurements of a sample is provided. The automated resonant waveguide cavity system includes a resonant cavity, a waveguide coupled to the resonant cavity, a programmable network analyzer (PNA) coupled to the waveguide, and a computing device. The computing device includes a memory storing processor executable code for a determination engine and a processor executing the processor executable code to cause the determination engine to obtain data from the PNA. The data is respective to the sample within the resonant cavity. The determination engine further integrates a plurality of analytical and modeling functions in determining the complex permittivity values of the sample from the data. |
| FILED | Wednesday, December 01, 2021 |
| APPL NO | 17/539582 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 22/00 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 27/2658 (20130101) Original (OR) Class Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 7/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 20220168810 | Watson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | 3D Systems, Inc. (Rock Hill, South Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan Watson (Santa Monica, California); Kirt Winter (San Diego, California) |
| ABSTRACT | A three-dimensional (3D) printing system for manufacturing a three-dimensional (3D) article includes a support powder dispenser containing support powder, a metal powder dispenser containing metal powder, a build plate, a beam system, and a controller. The controller is configured to (1) receive information defining a two-dimensional (2D) slice of the 3D article, (2) position the build plate to receive a new layer of metal powder, (3) operate the metal powder dispenser to dispense the new layer of metal powder, the new layer of metal powder spanning the 2D slice and extending beyond the boundaries to define a zone of unfused powder, (4) operate the beam system to selectively fuse the new layer of powder over an area corresponding to the 2D slice, (5) operate the support powder dispenser to dispense a bounding contour of support powder proximate to or overlapping the zone of unfused powder. |
| FILED | Monday, August 16, 2021 |
| APPL NO | 17/402783 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/05 (20220101) B22F 10/28 (20210101) Original (OR) Class B22F 10/85 (20210101) B22F 2302/256 (20130101) B22F 2304/10 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220169890 | Walters et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio) |
| ASSIGNEE(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio) |
| INVENTOR(S) | David N. Walters (Slippery Rock, Pennsylvania); Emily S. Reinhardt (Allison Park, Pennsylvania); Cynthia Kutchko (Pittsburgh, Pennsylvania); Stuart D. Hellring (Pittsburgh, Pennsylvania) |
| ABSTRACT | A coating composition includes a polymer prepared from a mixture of reactants including (a) a fluorinated polysiloxane and (b) an alkoxy silane functional resin. The alkoxy silane functional resin includes a polyurethane resin or an acrylic resin. A substrate at least partially coated with the coating composition is also disclosed. A method of condensing a polar fluid by contacting a substrate at least partially coated with the coating composition with a polar fluid, such that the polar fluid condenses on at least a portion of the coated substrate is also disclosed. |
| FILED | Tuesday, January 28, 2020 |
| APPL NO | 17/598941 |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/22 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 133/08 (20130101) C09D 133/10 (20130101) C09D 175/04 (20130101) C09D 183/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20220167613 | Reifenrath |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stratacor, Inc. (Novato, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | William Reifenrath (Novato, California) |
| ABSTRACT | This disclosure provides insect or arthropod pesticidal compositions of mono alpha carboxylic acids or esters thereof in combination with an emulsifier, an adjuvant comprising choline, and a carrier. Also provided are aqueous concentrates comprising the pesticidal compositions, as well as aqueous dilutions of the aqueous concentrates. Also provided are methods of killing or incapacitating insects or arthropods and methods of treating cattle to protect against biting insects or arthropods using such compositions. |
| FILED | Friday, October 01, 2021 |
| APPL NO | 17/492317 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 33/12 (20130101) Original (OR) Class A01N 37/02 (20130101) Biocidal, Pest Repellant, Pest Attractant or Plant Growth Regulatory Activity of Chemical Compounds or Preparations A01P 7/04 (20210801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220173567 | Sipes, JR. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | OPTICAL ENGINES, INC. (Colorado Springs, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Donald Lee Sipes, JR. (Colorado Springs, Colorado); Jason Tafoya (Colorado Springs, Colorado); Brian Michael Schulz (Colorado Springs, Colorado); James Lefort (Colorado Springs, Colorado); Daniel Scott Schulz (Colorado Springs, Colorado) |
| ABSTRACT | A fiber support assembly includes: a first glass tube, wherein the first glass tube is at tached to a microlens or lenslet of a microlens or lenslet array; a second glass tube at least partially disposed within the first glass tube; and a gain fiber disposed within the second glass tube, wherein the gain fiber has a first tapered end cap, and wherein the gain fiber with the first tapered end cap is aligned to the microlens or lenslet attached to the first glass tube. The fiber support assembly may further include: a pump fiber disposed within the second glass tube, wherein the pump fiber has a second tapered end cap; and a reflector configured to receive counter-pumping light from the pump fiber and direct the counter-pumping light to the first tapered end cap of the gain fiber. |
| FILED | Friday, January 14, 2022 |
| APPL NO | 17/576431 |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/06745 (20130101) H01S 3/094019 (20130101) Original (OR) Class H01S 3/094053 (20130101) H01S 3/094057 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 20220170842 | LEE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SOL INC. (Seoul, South Korea); Government of the United States of America, as Represented by the Secretary of Commerce (GAITHERSBURG, Maryland) |
| ASSIGNEE(S) | SOL INC. (Seoul, South Korea); Government of the United States of America, as Represented by the Secretary of Commerce (GAITHERSBURG, Maryland) |
| INVENTOR(S) | Jong Muk LEE (Seoul, South Korea); Darwin R. Reyes-Hernandez (Clarksburg, Maryland); Brian J. Nablo (Rockville, Maryland) |
| ABSTRACT | The inventive concept discloses a time series quantification method of supravital dye uptake of a cell using a lens-free imaging system. |
| FILED | Monday, November 30, 2020 |
| APPL NO | 17/106961 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1475 (20130101) Original (OR) Class G01N 33/5041 (20130101) G01N 2015/1452 (20130101) G01N 2015/1472 (20130101) G01N 2015/1488 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 20220169105 | Hill et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Proterra Inc. (Burlingame, California) |
| ASSIGNEE(S) | Proterra Inc. (Burlingame, California) |
| INVENTOR(S) | Dale Hill (New Braunfels, Texas); Michael Walker (Daly City, California); Shaun Onorato (Superior, Colorado); Donald Morris (Littleton, Colorado); Stephen Misencik (Raleigh, North Carolina); John Winkel (Thornton, Colorado) |
| ABSTRACT | A low-floor electric bus includes a plurality of battery packs mounted under the floor of such that the floor inside the bus between a front axle and a rear axle of the bus is substantially flat. Each battery pack may include an enclosure and multiple battery modules positioned within the enclosure. And, each battery module may include a plurality of battery cells electrically connected together. |
| FILED | Thursday, February 17, 2022 |
| APPL NO | 17/651542 |
| CURRENT CPC | Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles B60K 1/04 (20130101) Original (OR) Class B60K 6/20 (20130101) Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 3/0046 (20130101) B60L 50/62 (20190201) B60L 50/64 (20190201) B60L 50/66 (20190201) B60L 53/11 (20190201) B60L 58/12 (20190201) B60L 58/18 (20190201) B60L 58/21 (20190201) B60L 58/26 (20190201) Vehicles, Vehicle Fittings, or Vehicle Parts, Not Otherwise Provided for B60R 16/04 (20130101) Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 10/24 (20130101) Motor Vehicles; Trailers B62D 29/00 (20130101) B62D 29/02 (20130101) B62D 47/02 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/485 (20130101) H01M 10/42 (20130101) H01M 10/052 (20130101) H01M 10/613 (20150401) H01M 10/4207 (20130101) H01M 50/20 (20210101) H01M 50/502 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20220170908 | Wyss-Coray et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Anton WYSS-CORAY (Stanford, California); David GATE (Stanford, California); Mark DAVID (Stanford, California); Naresha SALIGRAMA (Stanford, California); David A. CASIMIR (Stanford, California); The Board of Trustees of the Leland Standford Junior Inivesity (Stanford, California); U.S Government as represented by The Department of Veterans Affair (Washibton, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anton Wyss-Coray (Stanford, California); David Gate (Stanford, California); Mark Davis (Stanford, California); Naresha Saligrama (Stanford, California) |
| ABSTRACT | Provided herein am compositions and methods for characterizing and treating neurodegenerative disease. In particular, provided herein are compositions and methods for measuring T cell markers associated with Alzheimer's disease. |
| FILED | Wednesday, March 25, 2020 |
| APPL NO | 17/442387 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Peptides C07K 14/7051 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/505 (20130101) Original (OR) Class G01N 33/6896 (20130101) G01N 2333/522 (20130101) G01N 2800/2821 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 20220169544 | Jolly |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Clifford D. Jolly (Parker, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Clifford D. Jolly (Parker, Colorado) |
| ABSTRACT | Systems and methods for delivering silver ion biocide are described herein. The systems described relate to passing water from a water system through a silver ion release module and optional high-concentration silver ion release module. The system includes an analyzer, detector, and/or controller for monitoring the concentration of silver ion and adjusting the flow path, flow rate, temperature and/or pH of the water in order to obtain the desired concentration of silver ion. The system optionally includes other metal ions released into a water system, the concentration of which may be used to automatically calibrate the described system and/or cause the system to take actions based on the measured concentration of silver ion or of the second metal ion. The system comprises a material that may be advantageous for silver ions in the systems. |
| FILED | Thursday, October 21, 2021 |
| APPL NO | 17/506827 |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/008 (20130101) C02F 1/505 (20130101) Original (OR) Class C02F 1/687 (20130101) C02F 1/688 (20130101) C02F 1/4606 (20130101) C02F 1/4672 (20130101) C02F 2201/4612 (20130101) C02F 2209/02 (20130101) C02F 2209/006 (20130101) C02F 2209/06 (20130101) C02F 2209/40 (20130101) C02F 2303/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, June 02, 2022.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-applications-20220602.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page