FedInvent™ Patent Applications
Application Details for Thursday, June 16, 2022
This page was updated on Monday, June 20, 2022 at 07:56 PM GMT
Department of Health and Human Services (HHS)
| US 20220183275 | WOODS et al. |
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| FUNDED BY |
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| APPLICANT(S) | OSSIUM HEALTH, INC. (San Francisco, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Erik J. WOODS (Carmel, Indiana); Brian H. JOHNSTONE (Fishers, Indiana); Dongsheng GU (Indianapolis, Indiana); Aubrey Marie SHERRY (Carmel, Indiana); Kelsey Gwen MUSALL (Avon, Indiana) |
| ABSTRACT | Methods, systems, and compositions are provided for extracting bone marrow cells from bone obtained from deceased donors, for preparing the bone marrow for cryopreservation, and for obtaining desired cells from cryopreserved and fresh bone marrow |
| FILED | Tuesday, March 01, 2022 |
| APPL NO | 17/684259 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0221 (20130101) A01N 1/0252 (20130101) A01N 1/0284 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220183286 | Julien et al. |
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| FUNDED BY |
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| APPLICANT(S) | EVOLVA SA (REINACH, Switzerland); THE U.S.A., AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (BETHESDA, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bryan N. Julien (Lexington, Kentucky); Marc C. Dolan (Wellington, Colorado); Roderick Stephen Bradbury (North Saanich, Canada) |
| ABSTRACT | Methods for repelling and killing ticks as well as for detaching attached and feeding ticks from the skin of a subject by application of a composition comprising nootkatone to the tick are disclosed. |
| FILED | Tuesday, January 04, 2022 |
| APPL NO | 17/568298 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 35/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220183561 | Lewis et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Laura Lewis (Boston, Massachusetts); Bruce Rosen (Charlestown, Massachusetts); Jonathan R. Polimeni (Cambridge, Massachusetts) |
| ABSTRACT | An imaging-based biomarker that indicates a neurological state of a subject is generated from magnetic resonance imaging data acquired from the subject while the subject was sleeping, or during both a sleep state and wake state. These magnetic resonance imaging data are acquired in such a way so that they simultaneously enable measurement of cerebrospinal fluid (“CSF”) flow and blood-oxygenation-level dependent (“BOLD”) signals. The imaging-based biomarker can be generated based on a correlation between CSF signals and BOLD signals extracted from these magnetic resonance imaging data. Using electroencephalography (“EEG”) data, CSF flow dynamics can also be estimated based on a physiological model in which coherent neural activity is modeled as entraining oscillations in blood volume and CSF. |
| FILED | Monday, April 13, 2020 |
| APPL NO | 17/602246 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) Original (OR) Class A61B 5/055 (20130101) A61B 5/0205 (20130101) A61B 5/374 (20210101) A61B 5/02007 (20130101) A61B 5/4088 (20130101) A61B 5/4809 (20130101) A61B 5/14542 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4806 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/10088 (20130101) G06T 2207/30016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220183562 | Clark et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Heather A. Clark (Lexington, Massachusetts); Kevin Bardon (Holbrook, Massachusetts); Nicole Langlois (Millbury, Massachusetts) |
| ABSTRACT | A DNA-based nanosensor system performs photoacoustic detection of cytokines. Cytokine receptors and a photoacoustic reporter dye are used in the nanosensor for cytokine detection, which can be reversible, and can be performed continuously, in vivo, in real time. Upon receptor binding to the cytokine, the DNA structure of the nanosensor closes to induce controlled dye stacking for photoacoustic application/interrogation, resulting in an increase in photoacoustic signal in the presence of the detected cytokine. The open or closed state of the sensor can be determined through differential signals as detected with photoacoustic imaging. A system using the nanosensor performs simultaneous multiplexed cytokine imaging, in the form of an inline and removable system paired with a clinical photoacoustic instrument. Cytokines can be detected in animal research use and in human point-of-care use. |
| FILED | Monday, December 13, 2021 |
| APPL NO | 17/549345 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0095 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220183565 | XIA et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Amherst, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jun XIA (Amherst, New York); Yuehang WANG (Buffalo, New York) |
| ABSTRACT | Devices and methods for photoacoustic tomography are disclosed herein. One exemplary photoacoustic tomography device uses a laser to produce acoustic waves in a sample. A transducer receives the acoustic waves through a slit formed by one or more blades positioned substantially parallel to the receiving aperture of the transducer. An acoustic absorber is affixed to each of the one or more blades along a surface proximal to the transducer. A processor acquires acoustic data and reconstructs photoacoustic tomographic images based on the acquired data. Reconstructing the image involves setting reconstruction parameters, defining a reconstruction area, reconstruction position, and pixel size, and calculating an acoustic travelling path for the sample to each transducer element. The acoustic travelling paths are saved into a three-dimensional array. |
| FILED | Tuesday, March 08, 2022 |
| APPL NO | 17/689123 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0073 (20130101) A61B 5/0095 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/1702 (20130101) G01N 29/24 (20130101) G01N 29/2418 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 23/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220183613 | NEITZ et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida); UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida); UNIVERSITY OF WASHINGTON (Seattle, Washington); UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| INVENTOR(S) | Jay NEITZ (Seattle, Washington); Maureen NEITZ (Seattle, Washington); James A. KUCHENBECKER (Seattle, Washington); William W. HAUSWIRTH (Gainesville, Florida) |
| ABSTRACT | The present invention provides reagents and methods for modulating cone photoreceptor activity, and devices for assessment of cone photoreceptor activity. |
| FILED | Wednesday, October 13, 2021 |
| APPL NO | 17/500426 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0036 (20180801) A61B 5/0048 (20130101) A61B 5/398 (20210101) Original (OR) Class A61B 5/4836 (20130101) A61B 5/4848 (20130101) A61B 5/6821 (20130101) A61B 5/7225 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 48/0058 (20130101) A61K 48/0075 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/0622 (20130101) A61N 2005/0652 (20130101) A61N 2005/0661 (20130101) A61N 2005/0663 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/85 (20130101) C12N 15/86 (20130101) C12N 2750/14132 (20130101) C12N 2750/14143 (20130101) C12N 2799/025 (20130101) C12N 2830/008 (20130101) C12N 2830/42 (20130101) C12N 2840/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20220183616 — METHODS AND SYSTEMS FOR CONTINUOUS MEASUREMENT OF ANOMALIES FOR DYSMORPHOLOGY ANALYSIS
| US 20220183616 | RILEY et al. |
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| FUNDED BY |
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| APPLICANT(S) | San Diego State University (SDSU) Foundation, dba San Diego State University Research Foundation (San Diego, California); BLUE RESONANCE, LLC (Encinitas, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Edward RILEY (San Diego, California); Ganapathy CHOCKALINGAM (Encinitas, California) |
| ABSTRACT | Computer-assisted methods for assisting in anomaly identification relating to a dysmorphology analysis comprise retrieving and/or generating a sequence of progressively changing images that depict morphing of at least a subject's first physical feature, between at least a first state representing an identification of a first anomaly relating to a dysmorphology and a second state representing lack of the identification of the first anomaly. The number of images in the sequence is selected to provide a substantially continuous transition between the first and second states. The retrieved and/or generated images are displayed on a display of a processing device, and a user interface on the processing device is provided for a user to make an image selection, which can then be used to determine identification or lack of identification of the anomaly. |
| FILED | Friday, March 06, 2020 |
| APPL NO | 17/432925 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/004 (20130101) A61B 5/1079 (20130101) A61B 5/4362 (20130101) Original (OR) Class A61B 5/7485 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 19/006 (20130101) G06T 2207/10016 (20130101) G06T 2207/10028 (20130101) G06T 2207/20081 (20130101) G06T 2207/20092 (20130101) G06T 2207/30201 (20130101) Image or Video Recognition or Understanding G06V 10/25 (20220101) G06V 40/165 (20220101) G06V 40/171 (20220101) G06V 2201/07 (20220101) G06V 2201/032 (20220101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/20 (20180101) G16H 50/20 (20180101) G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220183696 | Goldie et al. |
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| FUNDED BY |
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| APPLICANT(S) | Vivonics, Inc. (Bedford, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James H. Goldie (Lexington, Massachusetts); Brendan LaBrecque (Middleton, Massachusetts); Anna M Galea (Stow, Massachusetts); Eric Klem (Lexington, Massachusetts); Thomas Doyle (Brentwood, Tennessee); Ian Cohen (Broomfield, Colorado); Tim Robinson (Sandown, New Hampshire) |
| ABSTRACT | A pulmonary artery flow restrictor system includes a funnel shaped membrane with a proximal base and a restrictive distal opening which is stretchable to larger sizes. A self-expanding frame is attached to the proximal base of the membrane for securing the membrane within the pulmonary artery. |
| FILED | Wednesday, February 16, 2022 |
| APPL NO | 17/672893 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/12036 (20130101) Original (OR) Class A61B 17/12109 (20130101) A61B 17/12172 (20130101) A61B 17/12177 (20130101) A61B 2017/12054 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/82 (20130101) A61F 2002/068 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 29/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220183925 | Manwaring et al. |
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| FUNDED BY |
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| APPLICANT(S) | Kim H. Manwaring (Heber City, Utah); Jonathon D. Blotter (Heber City, Utah); Scott C. Steffensen (Provo, Utah); Kyle B. Bills (Springville, Utah); Jordan T. Yorgason (Provo, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kim H. Manwaring (Heber City, Utah); Jonathon D. Blotter (Heber City, Utah); Scott C. Steffensen (Provo, Utah); Kyle B. Bills (Springville, Utah); Jordan T. Yorgason (Provo, Utah) |
| ABSTRACT | This patent relates to the field of peripheral sensorimotor stimulation for the relief of symptoms and physical signs of distress including pain and anxiety and more specifically to addiction withdrawal. Peripheral stimulation of mechanoreceptors has been showed in a unique amplitude and frequency range to induce central effects of release of dopamine with a prolonged duration beyond stimulation in a model of addiction. Such stimulation can serve as an effective bridge during withdrawal from known addicting substances, including chemicals and behaviors, thus mitigating symptoms and potentially facilitating the cessation of drugs or substance seeking behavior. Interferential beat frequencies can be induced into the body using separately located sources of vibration to localize maxima and minima of stimulation. A conforming seat consisting of two separately driven halves induces a traveling wave due to interference or formation of beat frequencies which are driven in the therapeutic range to mitigate the symptoms and signs of withdrawal. Further, the beat frequencies can be monitored by a transducer to assure compliance of a treatment regimen and as a trigger pattern for focused exercises. |
| FILED | Thursday, April 23, 2020 |
| APPL NO | 17/437386 |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/005 (20130101) A61H 23/0245 (20130101) Original (OR) Class A61H 2201/1633 (20130101) A61H 2201/5043 (20130101) A61H 2201/5048 (20130101) A61H 2201/5058 (20130101) A61H 2201/5061 (20130101) A61H 2201/5079 (20130101) A61H 2201/5084 (20130101) A61H 2205/086 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184013 | Ghiaur et al. |
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| FUNDED BY |
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| APPLICANT(S) | Io Therapeutics, Inc. (Spring, Texas); The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gabriel Ghiaur (Baltimore, Maryland); Richard J. Jones (Baltimore, Maryland); Salvador Alonso (Baltimore, Maryland); Roshantha A. Chandraratna (Spring, Texas) |
| ABSTRACT | Disclosed herein are methods for treating a cancer comprising administering to a subject in need thereof an effective dose of a CYP26-resistant retinoic acid receptor (RAR) alpha (RARα) selective agonist, whereby as a result of the treatment the tumor burden is reduced in the subject and cancer stem cells resident in the bone marrow are substantially reduced. |
| FILED | Thursday, March 03, 2022 |
| APPL NO | 17/685661 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/58 (20130101) A61K 31/69 (20130101) A61K 31/138 (20130101) A61K 31/192 (20130101) A61K 31/196 (20130101) Original (OR) Class A61K 31/277 (20130101) A61K 31/454 (20130101) A61K 31/4166 (20130101) A61K 31/4196 (20130101) A61K 31/4545 (20130101) A61K 31/5685 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184020 | do Valle et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Italo Faria do Valle (Boston, Massachusetts); Albert-László Barábasi (Brookline, Massachusetts); Joseph Loscalzo (Boston, Massachusetts); Harvey George Roweth (Boston, Massachusetts); Michael William Malloy (Boston, Massachusetts); Elisabeth M. Battinelli (Chestnut Hill, Massachusetts) |
| ABSTRACT | Provided herein are methods of treating a vascular disease or condition in a subject in need thereof, comprising administering to the subject an effective amount of a vascular disease associated polyphenol (e.g., rosmarinic acid), or a pharmaceutically acceptable salt thereof. Also provided herein are methods of promoting or supporting vascular health in a subject, and methods of inhibiting platelet function (e.g., platelet aggregation) in a subject. |
| FILED | Tuesday, December 21, 2021 |
| APPL NO | 17/558402 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/122 (20130101) A61K 31/192 (20130101) A61K 31/216 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184036 | HE et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rosalind Franklin University of Medicine and Science (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Johnny HE (North Chicago, Illinois); Xiaojie ZHAO (North Chicago, Illinois) |
| ABSTRACT | In the present disclosure, doxycycline-inducible astrocyte-specific HIV Tat transgenic mice (iTat), a surrogate HAND model, were treated with PNU-125096, a positive allosteric modulator of α7 nicotinic acetylcholine receptor (α7 nAChR) and effects on Tat-induced behavioral impairments and neuropathologies were observed. This disclosure shows that PNU-125096 treatment significantly improved locomotor, learning and memory deficits of iTat mice while inhibited glial activation and increased PSD-95 expression in the cortex and hippocampus of iTat mice. α7 nAChR knockout eliminated the protective effects of PNU-125096 on iTat mice. In addition, inhibition of p38 phosphorylation by SB239063, a p38 MAPK-specific inhibitor, exacerbated Tat neurotoxicity in iTat mice. These findings demonstrated for the first time that α7 nAChR activation led to protection against HAND and suggest that α7 nAChR and PNU-125096 hold significant promise for development of therapeutics for HAND. |
| FILED | Friday, December 10, 2021 |
| APPL NO | 17/547472 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/41 (20130101) Original (OR) Class A61K 31/506 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184037 | Hoque et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mohammad O. Hoque (Baltimore, Maryland); David Sidransky (Baltimore, Maryland); Akira Oki (Baltimore, Maryland) |
| ABSTRACT | Methods for preventing or treating subjects having cancer based on the identification of pharmaceutical agents that target cancer stem cells (CSCs) have been identified. These methods include administering to the subject an effective amount of a COX2 inhibitor and an effective amount of a YAP1 inhibitor. In addition, methods of enhancing chemotherapeutic responses in cancer patients have been discovered and are described herein. |
| FILED | Tuesday, December 15, 2020 |
| APPL NO | 17/122726 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/407 (20130101) A61K 31/409 (20130101) A61K 31/415 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184042 | SPIEKERKOETTER et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Edda SPIEKERKOETTER (Redwood City, California); Marlene RABINOVITCH (Redwood City, California); Philip A. BEACHY (Redwood City, California); David SOLOW-CORDERO (Redwood City, California) |
| ABSTRACT | A method for reducing pulmonary hypertension in a mammal that employs FK506 is provided. In certain embodiments, the method comprises administering FK506 to a mammal having pulmonary arterial hypertension associated with defective MBPR2 signaling at a dosage sufficient to reduce blood pressure in the pulmonary artery of the mammal. |
| FILED | Wednesday, July 29, 2020 |
| APPL NO | 16/941778 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/436 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5041 (20130101) G01N 2333/912 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184043 | Sun et al. |
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| FUNDED BY |
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| APPLICANT(S) | MedRegen, LLC (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhaoli Sun (Perry Hall, Maryland); Xuhang Li (Clarksville, Maryland) |
| ABSTRACT | The present invention relates to the field of inflammatory bowel disease. In one aspect, the present invention provides methods for treating inflammatory bowel disease in a patient comprising administering to the patient a therapeutically effective amount of a stem cell mobilizer and an immunosuppressive agent. In particular embodiments, the present invention provides a method for treating inflammatory bowel disease in a patient comprising administering to the patient a therapeutically effective amount of an agent that mobilizes CD34+ and/or CD133+ stem cells and a low dose of an immunosuppressive agent. |
| FILED | Wednesday, March 02, 2022 |
| APPL NO | 17/684959 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/395 (20130101) A61K 31/436 (20130101) Original (OR) Class A61K 38/13 (20130101) A61K 38/193 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184047 | Villagra et al. |
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| FUNDED BY |
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| APPLICANT(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alejandro V. Villagra (Tampa, Florida); Eduardo M. Sotomayor (Tampa, Florida) |
| ABSTRACT | Disclosed herein is a method for modulating Program Death Receptor Ligand 1 (PDL1) in a cancer cell, comprising contacting the cell with a composition comprising a histone deacetylase (HDAC) inhibitor. Also disclosed is a method for treating a tumor in a subject, comprising administering to the subject a thereapeutically effective amount of a composition comprising a histone deacetylase (HDAC) inhibitor and a composition comprising a thereapeutically effective amount of a Program Death Receptor Ligand 1 (PDL1) inhibitor, a Programmed Death 1 receptor (PD1) inhibitor, or a combination thereof. |
| FILED | Thursday, March 03, 2022 |
| APPL NO | 17/685892 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/17 (20130101) A61K 31/416 (20130101) A61K 31/422 (20130101) A61K 31/437 (20130101) Original (OR) Class A61K 31/505 (20130101) A61K 31/506 (20130101) A61K 31/4045 (20130101) A61K 31/4406 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184071 | PAYNE et al. |
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| FUNDED BY |
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| APPLICANT(S) | GlaxoSmithKline Intellectual Property Development Limited (Brentford, Middlesex, United Kingdom) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David John PAYNE (Collegeville, Pennsylvania); Stephen RITTENHOUSE (Collegeville, Pennsylvania); Nicole SCANGARELLA-OMAN (Collegeville, Pennsylvania) |
| ABSTRACT | Disclosed are methods and compounds for use for treating urinary tract infection comprising administering gepotidacin or a pharmaceutically acceptable salt thereof, in a therapeutically effective amount in a human in need thereof, wherein the urinary tract infection is caused by one or more bacterium as defined herein. |
| FILED | Wednesday, April 03, 2019 |
| APPL NO | 17/600660 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4985 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184098 | DAMSKER et al. |
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| FUNDED BY |
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| APPLICANT(S) | ReveraGen BioPharma, Inc. (Rockville, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jesse DAMSKER (Alexandria, Virginia); Eric Hoffman (Rockville, Maryland) |
| ABSTRACT | The present disclosure provides methods of treating or reducing the symptoms of muscular dystrophy in a human patient between the age of 1 day and 18 years old, comprising administering to the human patient in need thereof a therapeutically effective amount of a vamorolone and/or a salt thereof. |
| FILED | Monday, February 21, 2022 |
| APPL NO | 17/651879 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/573 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184109 | Arboleda-Velasquez et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Schepens Eye Research Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph F. Arboleda-Velasquez (Newton, Massachusetts); Leo A. Kim (Brookline, Massachusetts); Patricia A. D`Amore (Boston, Massachusetts) |
| ABSTRACT | The present subject matter provides compositions, formulations, and methods for inhibiting, treating, or preventing aberrant angiogenesis in a subject. |
| FILED | Thursday, December 09, 2021 |
| APPL NO | 17/547008 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/5513 (20130101) A61K 31/7088 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) A61P 35/04 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184111 | Roberts et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | David D. Roberts (Bethesda, Maryland); David R. Soto Pantoja (Rockville, Maryland) |
| ABSTRACT | Disclosed herein are methods of reducing cytotoxicity of a chemotherapeutic agent to non-cancer cells by administering to a subject with cancer an effective amount of an agent that inhibits CD47 signaling and a chemotherapeutic agent. Example disclosed methods reduce cardiotoxicity of a chemotherapeutic agent. Also disclosed are methods of increasing cytotoxicity of a chemotherapeutic agent in cancer cells by administering to a subject with a tumor an effective amount of an agent that inhibits CD47 signaling and a chemotherapeutic agent. In some embodiments, the inhibitor of CD47 signaling is administered to the subject before, during, or after the administration of the chemotherapeutic agent. |
| FILED | Monday, February 28, 2022 |
| APPL NO | 17/682655 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/52 (20130101) A61K 31/65 (20130101) A61K 31/137 (20130101) A61K 31/351 (20130101) A61K 31/365 (20130101) A61K 31/437 (20130101) A61K 31/505 (20130101) A61K 31/513 (20130101) A61K 31/704 (20130101) A61K 31/706 (20130101) A61K 31/711 (20130101) A61K 31/712 (20130101) A61K 31/713 (20130101) Original (OR) Class A61K 31/787 (20130101) A61K 31/7064 (20130101) A61K 39/39558 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 39/00 (20180101) Peptides C07K 16/2803 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184121 | BUTTE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Manish BUTTE (Los Angeles, California); Fatemeh MAJEDI (Los Angeles, California); Mohammad Mahdi HASANI-SADRABADI (Los Angeles, California) |
| ABSTRACT | Aspects of the present disclosure provide methods and compositions for immune cell activation. Disclosed are antibody-coated microparticles and methods for use. In some cases, immune cell activation methods comprising mechanical stimulation are disclosed. Embodiments are directed to activation of cytotoxic T cells. Additional aspects include generation and activation of regulatory T cells. |
| FILED | Wednesday, March 18, 2020 |
| APPL NO | 17/440116 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0638 (20130101) C12N 2501/51 (20130101) C12N 2501/515 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184125 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Dongfang Liu (Millburn, New Jersey); Minh Ma (New Brunswick, New Jersey); Saiaditya Badeti (New Brunswick, New Jersey) |
| ABSTRACT | Chimeric antigen receptors (CARs) including an scFv binding to coronavirus spike protein (S309 scFv), nucleic acids encoding the CARs, vectors including nucleic acids encoding the CARs, and cells expressing the CARs are provided. Methods of treating a subject with coronavirus are also provided, including administering to the subject a modified immune cell expressing a disclosed CAR. |
| FILED | Tuesday, December 14, 2021 |
| APPL NO | 17/551006 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/00 (20130101) A61K 39/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/5443 (20130101) C07K 14/7051 (20130101) C07K 14/7151 (20130101) C07K 14/70521 (20130101) C07K 16/10 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184143 | Stamler |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan S. Stamler (Cleveland, Ohio) |
| ABSTRACT | A method of treating a disorder associated gasotransmitter signaling in a subject in need thereof includes modulating the microbiota of the subject to modulate microbiota gasotransmitter production and modification of the subject's proteome to treat the disorder in the subject. |
| FILED | Wednesday, February 19, 2020 |
| APPL NO | 17/432225 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/04 (20130101) A61K 33/04 (20130101) A61K 35/74 (20130101) Original (OR) Class A61K 2035/115 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184144 | Hsiao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Elaine Y. Hsiao (Los Angeles, California); Jessica Yano (Los Angeles, California); Helen E. Vuong (Los Angeles, California); Christine Olson (Los Angeles, California) |
| ABSTRACT | Provided herein are methods and compositions related to treating or preventing seizures. In some aspects, provided herein are methods of treating or preventing seizures in a subject by administering to the subject a composition comprising Parabacteroides and Akkermansia bacteria. |
| FILED | Monday, September 27, 2021 |
| APPL NO | 17/486299 |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/30 (20160801) A23L 33/135 (20160801) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0031 (20130101) A61K 35/74 (20130101) Original (OR) Class A61K 39/0216 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184147 | Blaustein et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestem University (Evanston, Illinois); Ann and Robert H. Lurie Children's Hospital of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ryan A. Blaustein (Evanston, Illinois); Patrick C. Seed (Chapel Hill, North Carolina); Erica M. Hartmann (Chicago, Illinois) |
| ABSTRACT | Abstract: Disclosed are methods and compositions for treating a subject where the subject is undergoing or is about to undergo treatment with an anthracycline chemotherapeutic. In the disclosed methods, a subject may be administered an anthracycline chemotherapeutic and the subject further may be administered a detoxifying therapeutic agent that detoxifies the anthracycline chemotherapeutic, such as one or more enzymes that catalyze metabolism of the anthracycline chemotherapeutic or one or more probiotic organisms that express the one or more enzymes that catalyze metabolism of the anthracycline chemotherapeutic. |
| FILED | Wednesday, March 04, 2020 |
| APPL NO | 17/436501 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 35/741 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/14 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184150 | Chatila et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts); CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts); CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Talal A. Chatila (Belmont, Massachusetts); Lynn Bry (Jamaica Plain, Massachusetts); Georg Gerber (Boston, Massachusetts); Azza Abdel-Gadir (Boston, Massachusetts); Rima Rachid (Belmont, Massachusetts) |
| ABSTRACT | Disclosed are methods and compositions for the prevention and treatment of food allergy. In particular, described herein are microbial consortia, including minimal microbial consortia, that can prevent and/or cure food allergy. In certain embodiments, the consortia comprise certain members of the taxa Clostridiales and/or Bacteroidetes. |
| FILED | Wednesday, July 21, 2021 |
| APPL NO | 17/381843 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/19 (20130101) A61K 9/0053 (20130101) A61K 35/74 (20130101) A61K 35/741 (20130101) A61K 35/742 (20130101) Original (OR) Class A61K 35/744 (20130101) A61K 35/745 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/00 (20180101) A61P 37/08 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184151 | FICHOROVA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Raina FICHOROVA (Chestnut Hill, Massachusetts); Andrew ONDERDONK (Westwood, Massachusetts); Hidemi YAMAMOTO (Medford, Massachusetts); Mary DELANEY (Belmont, Massachusetts); Andrea DUBOIS (Roslindale, Massachusetts) |
| ABSTRACT | Described herein are methods and compositions for the use of treating and/or preventing vaginal bacterial infection and promoting healthy vaginal flora. Aspects of the invention relate to administering to a subject in need thereof a composition comprising a bacterial mixture of L. crispatus, L. gasseri, and L. jensenii. |
| FILED | Wednesday, December 08, 2021 |
| APPL NO | 17/545777 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0034 (20130101) A61K 31/4164 (20130101) A61K 31/7016 (20130101) A61K 31/7056 (20130101) A61K 31/7076 (20130101) A61K 35/747 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2035/115 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 1/205 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184172 | Salitiel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Alan Salitiel (La Jolla, California); Peng Zhao (La Jolla, California) |
| ABSTRACT | The present disclosure provides a method of preventing and/or treating hepatocellular apoptosis and liver damage in a liver disease, particularly NASH, by targeting the AMPK/caspase-6 axis to inhibit caspase-6 activity and/or activate AMPK activity. Also disclosed is the pharmaceutical composition for preventing and/or treating a liver disease comprising one or more caspase-6 inhibitor and/or AMPK activator of the present disclosure. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure. |
| FILED | Saturday, April 18, 2020 |
| APPL NO | 17/602966 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4365 (20130101) A61K 38/07 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/16 (20180101) A61P 43/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184181 | Cochran |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jennifer R. Cochran (Stanford, California) |
| ABSTRACT | The present invention provides HGF polypeptide variants, including dimers, for use in treatment, in particular to treat ocular diseases and disorders. |
| FILED | Monday, April 27, 2020 |
| APPL NO | 17/603311 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1833 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184197 | Scott et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Evan A. Scott (Northfield, Illinois); Chyung-Ru Wang (Evanston, Illinois); Shaobin Shang (Evanston, Illinois); Dina Kats (Evanston, Illinois) |
| ABSTRACT | Provided herein are subunit vaccine compositions comprising a nanocarrier and a lipid antigen, a peptide antigen or combinations thereof that elicit bother a CD1-restricted and an MHC-restricted T cell response in a subject. Methods for making and using the subunit vaccine compositions are also provided. |
| FILED | Monday, December 20, 2021 |
| APPL NO | 17/645288 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/51 (20130101) A61K 39/04 (20130101) Original (OR) Class A61K 2039/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184200 | BASLER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Atlanta, Georgia) |
| ASSIGNEE(S) | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Atlanta, Georgia) |
| INVENTOR(S) | Christopher F. BASLER (Atlanta, Georgia); JoAnn M. TUFARIELLO (Atlanta, Georgia); Lin WANG (Atlanta, Georgia) |
| ABSTRACT | Provided herein are virus-like particles and their uses for stimulating anti-pathogenic and anti-cancer immune responses. |
| FILED | Friday, March 20, 2020 |
| APPL NO | 17/441588 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/04 (20130101) A61K 39/12 (20130101) Original (OR) Class A61K 2039/5258 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/06 (20180101) A61P 31/14 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184201 | Weissman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Drew Weissman (Wynnewood, Pennsylvania); Norbert Pardi (Philadelphia, Pennsylvania); Michael Hogan (Philadelphia, Pennsylvania) |
| ABSTRACT | The present invention relates to compositions and methods for inducing an adaptive immune response against Zika virus (ZIKV) in a subject. In certain embodiments, the present invention provides a composition comprising a nucleoside-modified nucleic acid molecule encoding a ZIKV antigen, adjuvant, or a combination thereof. For example, in certain embodiments, the composition comprises a vaccine comprising a nucleoside-modified nucleic acid molecule encoding a ZIKV antigen, adjuvant, or a combination thereof. |
| FILED | Wednesday, December 22, 2021 |
| APPL NO | 17/559190 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5123 (20130101) A61K 39/12 (20130101) Original (OR) Class A61K 2039/53 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184202 | BARBER |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MIAMI (MIAMI, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF MIAMI (MIAMI, Florida) |
| INVENTOR(S) | GLEN N BARBER (MIAMI, Florida) |
| ABSTRACT | The invention relates to a vector and/or vaccine that can be used for therapeutic and preventive purposes. The virus is based on vesicular stomatitis virus (VSV) with a substituted VSV G (glycoprotein) for HTLV-1 G, referred to as gp62. The vector and/or vaccine further comprise a fusion protein comprising HTLV-1 regulatory proteins (HBZ and TAX) together to make a fusion product (HBZ-TAX) and mutated versions thereof. The vector and/or vaccine do not impede innate immune signaling and generate neutralizing antibodies and CTLs to gp62, HBZ, and TAX. |
| FILED | Friday, April 10, 2020 |
| APPL NO | 17/603331 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/5256 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184207 | MARTIN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ADJUVANCE TECHNOLOGIES, INC. (Lincoln, Nebraska) |
| ASSIGNEE(S) | ADJUVANCE TECHNOLOGIES, INC. (Lincoln, Nebraska) |
| INVENTOR(S) | J Tyler MARTIN (Roca, Nebraska); Jeffrey GARDNER (New York, New York) |
| ABSTRACT | The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases and cancers. |
| FILED | Friday, March 04, 2022 |
| APPL NO | 17/687094 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 39/00 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 2039/55577 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184225 | TILTON et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John C. TILTON (Cleveland, Ohio); Zach TROYER (Cleveland, Ohio) |
| ABSTRACT | The present disclosure relates to isolated, therapeutic agent delivery platforms and, more particularly, to engineered, fusogenic particles and related methods for targeted delivery of therapeutic agents to cells. One aspect of the present disclosure relates to an isolated, fusogenic particle including a lipid envelope associated with at least one targeting protein, and a therapeutic agent contained within the fusogenic particle. The at least one targeting protein can be a viral fusion protein or a cognate receptor of a viral fusion protein. Other aspects of the present disclosure relate to in vivo and in vitro methods for delivering therapeutic agents to cells using the fusogenic particles. |
| FILED | Thursday, April 23, 2020 |
| APPL NO | 17/605585 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1271 (20130101) A61K 47/62 (20170801) A61K 47/6911 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2760/20222 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184226 | Spiller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Drexel Univeristy (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Kara Lorraine Spiller (Glenside, Pennsylvania); Amanda Elizabeth Pentecost (Blackwood, New Jersey); Yury Gogotsi (Ivyland, Pennsylvania) |
| ABSTRACT | One aspect of the invention provides a method for reducing inflammation in a patient including locally administering a composition comprising a complex comprising octadecylamine surface-functionalized nanodiamonds with dexamethasone bound to octadecylamine. Another aspect of the invention provides a method for reducing inflammation in a patient comprising locally administering a composition including octadecylamine surface-functionalized nanodiamonds, wherein no therapeutic agent is bound to the nanodiamonds. |
| FILED | Thursday, March 03, 2022 |
| APPL NO | 17/653304 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/573 (20130101) A61K 47/52 (20170801) A61K 47/6923 (20170801) Original (OR) Class A61K 47/6929 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184229 | Gersbach et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Charles A. Gersbach (Chapel Hill, North Carolina); Karen Bulaklak (Durham, North Carolina); Jacqueline N. Robinson-Hamm (Durham, North Carolina) |
| ABSTRACT | Disclosed herein are therapeutic targets for the correction of the human dystrophin gene by gene editing and methods of use. |
| FILED | Tuesday, April 14, 2020 |
| APPL NO | 17/603330 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/86 (20130101) C12N 15/111 (20130101) C12N 2310/20 (20170501) C12N 2320/32 (20130101) C12N 2750/14143 (20130101) C12N 2800/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184411 | Dong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Pulsethera, Inc. (Chestnut Hill, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pu-Ting Dong (Boston, Massachusetts); Jie Hui (Boston, Massachusetts); Ji-Xin Cheng (Newton, Massachusetts); Yifan Zhu (Allston, Massachusetts) |
| ABSTRACT | Methods of the present invention comprise photoinactivation of catalase in combination with low-concentration peroxide solutions and/or ROS generating agents to provide antibacterial effects. |
| FILED | Thursday, March 03, 2022 |
| APPL NO | 17/685897 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/40 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/10 (20130101) A61L 2/208 (20130101) A61L 2101/02 (20200801) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) Original (OR) Class A61N 5/0616 (20130101) A61N 5/0624 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184416 | FLYNN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITYOF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | RYAN T. FLYNN (Iowa City, Iowa); QUENTIN E. ADAMS (Iowa City, Iowa) |
| ABSTRACT | A rotating shield brachytherapy (RSBT) apparatus includes a radiation source, at least one applicator, a catheter, a catheter drive assembly, a robotic positioning system, and a connection system. The applicator(s) is configured to be inserted or implanted into a patient. A distal end portion of the catheter has at least one radiation shield and is configured to receive a wire-mounted radiation source. The catheter drive assembly causes helical motion of the catheter and engages the proximal end portion of the catheter to selectively rotate the catheter about a longitudinal axis. The robotic positioning system aligns the catheter drive assembly, in both position and angular orientation at a modifiable rate, with the applicator(s), or to any programmed point in space. The connection system couples the catheter drive assembly to the applicator(s), and further decouple the catheter drive from the applicator(s). When the applicator(s) is coupled to the catheter drive assembly, the catheter can be advanced into, and out of, the at least one applicator at a variable rate through operation of the catheter drive a |
| FILED | Wednesday, March 18, 2020 |
| APPL NO | 17/440375 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1002 (20130101) A61N 5/1007 (20130101) Original (OR) Class A61N 2005/1009 (20130101) A61N 2005/1018 (20130101) A61N 2005/1025 (20130101) A61N 2005/1094 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220185777 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jinkun Chen (Lexington, Massachusetts); Qisheng Tu (Newton, Massachusetts); Xingwen Wu (Boston, Massachusetts); Gang Chen (Shanghai, China PRC) |
| ABSTRACT | Disclosed herein are adiponectin receptor agonists and methods of using the same for the treatment of inflammation or bone loss in a subject. |
| FILED | Tuesday, December 14, 2021 |
| APPL NO | 17/550834 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/08 (20180101) A61P 29/00 (20180101) Heterocyclic Compounds C07D 211/58 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220185792 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Chenglong Li (Gainesville, Florida); Xiaozhi Yang (Gainesville, Florida); Wei Zhou (Gaithersburg, Maryland) |
| ABSTRACT | A series of PRMT5 inhibitor compounds are described. The compounds are useful as PRMT5 inhibitor compounds and in the treatment of PRMT5 mediated diseases, disorders, and symptoms thereof. |
| FILED | Friday, March 27, 2020 |
| APPL NO | 17/599505 |
| CURRENT CPC | Heterocyclic Compounds C07D 209/86 (20130101) C07D 401/12 (20130101) C07D 401/14 (20130101) Original (OR) Class C07D 403/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220185798 | NEWMAN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (Rockville, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Amy Hauck NEWMAN (Phoenix, Arizona); Vivek KUMAR (Baltimore, Maryland); Anver Basha SHAIK (Baltimore, Maryland) |
| ABSTRACT | Disclosed herein novel dopamine D3 receptor selective antagonists/partial agonists compounds with high affinity and metabolic stability useful for the treatment of psychiatric and neurological disorders and as research and diagnostic tools. Also disclosed are methods of making the compounds. |
| FILED | Thursday, March 03, 2022 |
| APPL NO | 17/685709 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/36 (20180101) Heterocyclic Compounds C07D 403/12 (20130101) Original (OR) Class C07D 405/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220185803 | Babich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | John W. Babich (New York, New York); Justin Wilson (Ithaca, New York); Nikki Thiele (Brooktondale, New York); James Kelly (New York, New York); Shashikanth Ponnala (Ithaca, New York) |
| ABSTRACT | The present technology provides compounds as well as compositions including such compounds useful in targeted radiotherapy of cancer and/or mammalian tissue overexpressing prostate specific membrane antigen (“PSMA”) where the compounds are represented by the following: or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt thereof, wherein M1 is independently at each occurrence an alpha-emitting radionuclide. Equivalents of such compounds are also disclosed. |
| FILED | Wednesday, February 23, 2022 |
| APPL NO | 17/678782 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/0463 (20130101) A61K 51/0482 (20130101) A61K 51/1072 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 59/002 (20130101) Heterocyclic Compounds C07D 413/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220185821 | AL ABED et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | COLD SPRING HARBOR LABORATORY (Cold Spring Harbor, New York); THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (Manhasset, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yousef AL ABED (Dix Hills, New York); Lingbo ZHANG (Woodside, New York) |
| ABSTRACT | This disclosure generally relates to treating anemias. More specifically, the disclosure relates to use of muscarinic acetylcholine receptor subtype 4 antagonists, such as small molecule compounds, to promote self-renewal of burst forming unit erythroid (BFU-E) cells and treat anemias. |
| FILED | Friday, March 20, 2020 |
| APPL NO | 17/442926 |
| CURRENT CPC | Heterocyclic Compounds C07D 401/06 (20130101) C07D 498/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220185827 | KIMBALL et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| INVENTOR(S) | Spencer David KIMBALL (New Brunswick, New Jersey); Darren R. CARPIZO (New Brunswick, New Jersey); John A. GILLERAN (New Brunswick, New Jersey) |
| ABSTRACT | The invention provides a complex comprising Zn2+ and a compound of formula (I): or a deuterated analog thereof, or an ion or poly-ion thereof, or a salt thereof that is useful for treating cancer, as well as compositions and kits comprising such complexes. |
| FILED | Wednesday, April 22, 2020 |
| APPL NO | 17/605795 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Heterocyclic Compounds C07D 213/68 (20130101) C07D 401/12 (20130101) C07D 405/12 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 3/003 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220185845 | Hughes et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NovoBiotic Pharmaceuticals, LLC (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dallas Hughes (Bolton, Massachusetts); Amy Spoering (Waltham, Massachusetts); Aaron J. Peoples (Somerville, Massachusetts); Losee Lucy Ling (Arlington, Massachusetts); Anthony Nitti (Lexington, Massachusetts); William Millett (Worcester, Massachusetts); Ashley Zullo (Cambridge, Massachusetts); Kim Lewis (Newton, Massachusetts); Slava Epstein (Dedham, Massachusetts); Alysha Desrosiers (Medford, Massachusetts); Catherine Achorn (Cambridge, Massachusetts); Kelly Demeo (Brookline, Massachusetts) |
| ABSTRACT | The present invention relates generally to novel depsipeptides, to methods for the preparation of the novel depsipeptides, to pharmaceutical compositions comprising the novel depsipeptides; and to methods of using the novel depsipeptides to treat or inhibit various disorders. |
| FILED | Thursday, November 11, 2021 |
| APPL NO | 17/524230 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Peptides C07K 11/02 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220185855 | Laezza et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Texas-Medical Branch (TMB) (Galveston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Fernanda Laezza (Galveston, Texas); Jia Zhou (Galveston, Texas); Jin Mo Chung (Galveston, Texas); Plngyuan Wang (Galveston, Texas); Jun-Ho La (Galveston, Texas); Oluwarotimi Folorunso (Galveston, Texas); Aditya Singh (Galveston, Texas) |
| ABSTRACT | The present invention relates to novel small molecules Formula I and pharmaceutically acceptable salts thereof as well as the preparation and the use thereof to inhibit FGF13-1b. |
| FILED | Friday, January 24, 2020 |
| APPL NO | 17/425688 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/04 (20180101) Peptides C07K 5/1024 (20130101) C07K 14/50 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220185860 | IRVINE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (MITN1) (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Darrell J. IRVINE (Arlington, Massachusetts); Yiran ZHENG (Cambridge, Massachusetts); Li TANG (Quincy, Massachusetts) |
| ABSTRACT | The present disclosure is directed, in some embodiments, to methods and compositions of comprising a cell having a non-internalizing receptor, and a nanoparticle surface-modified with a ligand that binds to the non-internalizing receptor. |
| FILED | Monday, February 28, 2022 |
| APPL NO | 17/682633 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 39/0011 (20130101) A61K 39/001104 (20180801) A61K 47/60 (20170801) A61K 47/6849 (20170801) A61K 47/6889 (20170801) A61K 47/6903 (20170801) A61K 47/6913 (20170801) Peptides C07K 14/55 (20130101) Original (OR) Class C07K 14/5443 (20130101) C07K 14/7051 (20130101) C07K 14/7155 (20130101) C07K 14/70503 (20130101) C07K 14/70517 (20130101) C07K 14/70578 (20130101) C07K 14/70589 (20130101) C07K 16/30 (20130101) C07K 16/289 (20130101) C07K 16/2806 (20130101) C07K 16/2845 (20130101) C07K 19/00 (20130101) C07K 2319/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0638 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220185866 | Boice et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Henry Boice (San Mateo, California); Hans Guido Wendel (New York, New York); Darin Salloum (New York, New York) |
| ABSTRACT | In some aspects the present invention provides methods for the treatment of B-cell lymphomas. Some such methods involve administration of HVEM ectodomain polypeptides, anti-HVEM antibodies, or anti-BTLA antibodies to subjects in need thereof. Some such methods involve use of CAR T cells, such as CD19-specific CAR T cells. The present invention also provides compositions useful in such methods. These and other embodiments of the present invention and described further herein. |
| FILED | Saturday, February 26, 2022 |
| APPL NO | 17/681737 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/1793 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7051 (20130101) C07K 14/70521 (20130101) C07K 14/70578 (20130101) Original (OR) Class C07K 16/2803 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220185867 | DeMartino et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Anthony W. DeMartino (Pittsburgh, Pennsylvania); Jason J. Rose (Fox Chapel, Pennsylvania); Qinzi Xu (Wexford, Pennsylvania); Mark T. Gladwin (Pittsburgh, Pennsylvania); Jesus Tejero Bravo (Pittsburgh, Pennsylvania) |
| ABSTRACT | Compositions that include a globin, such as hemoglobin, in a relaxed state are described. Globin molecules in a relaxed state (R state) have a higher binding affinity for carbon monoxide and oxygen than globin molecules in a tense state (T state). Hemoglobin in a relaxed state can be, for example, hemoglobin that is substantially free of 2,3-diphosphoglycerate or hemoglobin that includes a β-Cys93 that is covalently modified to inhibit one or both salt bridges between β-Asp94, β-His146 and α-Lys40. Methods for using these compositions, such as for treating carbon monoxide poisoning, and methods for producing these compositions, are also disclosed. |
| FILED | Thursday, April 02, 2020 |
| APPL NO | 17/601039 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/805 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220185870 | PILEWSKI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kelsey PILEWSKI (Nashville, Tennessee); Ivelin Stefanov GEORGIEV (Brentwood, Tennessee) |
| ABSTRACT | The present disclosure relates to antibodies and uses thereof for treating an HIV infection, an HCV infection, or an HIV/HCV co-infection. |
| FILED | Friday, April 03, 2020 |
| APPL NO | 17/600893 |
| CURRENT CPC | Peptides C07K 16/109 (20130101) C07K 16/1045 (20130101) Original (OR) Class C07K 2317/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220185871 | HAYNES et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Barton F. HAYNES (Durham, North Carolina); Kevin J. WIEHE (Durham, North Carolina); Mattia BONSIGNORI (Durham, North Carolina) |
| ABSTRACT | The invention is directed to methods to identify improbable mutations in the heavy or light chain variable domain of an antibody, methods to identify antigens which bind to antibodies comprising such improbable mutations, and methods of using such antigens to induce immune responses. |
| FILED | Wednesday, October 13, 2021 |
| APPL NO | 17/500750 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/21 (20130101) Peptides C07K 16/1063 (20130101) Original (OR) Class C07K 2317/55 (20130101) C07K 2317/56 (20130101) C07K 2317/92 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/16034 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220185883 | Sabatos-Peyton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Novartis AG (Basel, Switzerland); DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts); The Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Catherine Anne Sabatos-Peyton (Cambridge, Massachusetts); Barbara Brannetti (Cambridge, Massachusetts); Alan S. Harris (Cambridge, Massachusetts); Thomas Huber (Basel, Switzerland); Thomas Pietzonka (Basel, Switzerland); Jennifer Marie Mataraza (Cambridge, Massachusetts); Walter A. Blattler (Brookline, Massachusetts); Daniel J. Hicklin (Montclair, New Jersey); Maximiliano Vasquez (Palo Alto, California); Rosemarie H. DeKruyff (Portola Valley, California); Dale T. Umetsu (Portola Valley, California); Gordon James Freeman (Brookline, Massachusetts); Tiancen Hu (Cambridge, Massachusetts); John A. Taraszka (Cambridge, Massachusetts); Fangmin Xu (Cambridge, Massachusetts) |
| ABSTRACT | Antibody molecules that specifically bind to TIM-3 are disclosed. The anti-TIM-3 antibody molecules can be used to treat, prevent and/or diagnose immune, cancerous, or infectious conditions and/or disorders. |
| FILED | Friday, September 24, 2021 |
| APPL NO | 17/484794 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/395 (20130101) A61K 39/3955 (20130101) A61K 39/39558 (20130101) A61K 45/06 (20130101) Peptides C07K 16/2803 (20130101) Original (OR) Class C07K 2299/00 (20130101) C07K 2317/24 (20130101) C07K 2317/31 (20130101) C07K 2317/34 (20130101) C07K 2317/51 (20130101) C07K 2317/52 (20130101) C07K 2317/55 (20130101) C07K 2317/56 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) C07K 2317/515 (20130101) C07K 2317/565 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 33/57492 (20130101) G01N 2333/70596 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20220185898 — METHODS OF USE OF ANTI-SORTILIN ANTIBODIES FOR TREATING A DISEASE, DISORDER, OR INJURY
| US 20220185898 | ROSENTHAL et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alector LLC (South San Francisco, California) |
| ASSIGNEE(S) | Alector LLC (South San Francisco, California) |
| INVENTOR(S) | Arnon ROSENTHAL (Woodside, California); Tina SCHWABE (San Francisco, California); Michael KURNELLAS (San Francisco, California); Robert PEJCHAL (Lebanon, New Hampshire); Anthony B. COOPER (Lebanon, New Hampshire) |
| ABSTRACT | The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind on or more epitopes within a Sortilin protein, e.g., human Sortilin or a mammalian Sortilin, and use of such compostions in preventing, reducing risk, or treating an individual in need thereof. |
| FILED | Tuesday, November 23, 2021 |
| APPL NO | 17/534270 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) Peptides C07K 16/286 (20130101) C07K 16/2863 (20130101) Original (OR) Class C07K 2317/14 (20130101) C07K 2317/21 (20130101) C07K 2317/31 (20130101) C07K 2317/34 (20130101) C07K 2317/55 (20130101) C07K 2317/56 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2319/30 (20130101) C07K 2319/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220185899 | ROSENTHAL et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alector LLC (South San Francisco, California) |
| ASSIGNEE(S) | Alector LLC (South San Francisco, California) |
| INVENTOR(S) | Arnon ROSENTHAL (Woodside, California); Tina SCHWABE (San Francisco, California); Michael KURNELLAS (San Francisco, California); Robert PEJCHAL (Lebanon, New Hampshire); Anthony B. COOPER (Lebanon, New Hampshire) |
| ABSTRACT | The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind on or more epitopes within a Sortilin protein, e.g., human Sortilin or a mammalian Sortilin, and use of such compostions in preventing, reducing risk, or treating an individual in need thereof. |
| FILED | Tuesday, November 23, 2021 |
| APPL NO | 17/534291 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) Peptides C07K 16/286 (20130101) C07K 16/2863 (20130101) Original (OR) Class C07K 2317/14 (20130101) C07K 2317/21 (20130101) C07K 2317/31 (20130101) C07K 2317/34 (20130101) C07K 2317/55 (20130101) C07K 2317/56 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2319/30 (20130101) C07K 2319/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220186055 | Jiang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhouran Jiang (Baltimore, Maryland); Devina Chatterjee (Baltimore, Maryland); Galip Ozan Erol (Baltimore, Maryland); David H. Gracias (Baltimore, Maryland); Sung Hoon Kang (Baltimore, Maryland); Lewis Romer (Baltimore, Maryland); Narutoshi Hibino (Baltimore, Maryland) |
| ABSTRACT | Provided are compositions (which may inks), methods, devices, and systems that are used with 3D printing. The compositions contain fluoropolymer particles, one or more type of a medium, one or more surfactants, and one or more shear thinning agents. The fluoropolymer component can be one or more of polytetrafluoroethylene (PTFE), perfluoroalkoxy, fluorinated ethylene-propylene, and poly ethyl enetetrafluoroethylene. Cartridges that contain the compositions are also provided. Methods of making the compositions, methods of using the compositions for 3D printing, and articles of manufacture, such as medical devices, are also provided. |
| FILED | Sunday, April 19, 2020 |
| APPL NO | 17/604648 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/112 (20170801) B29C 64/209 (20170801) B29C 64/314 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) Compositions of Macromolecular Compounds C08L 5/00 (20130101) C08L 27/18 (20130101) C08L 2203/02 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/102 (20130101) C09D 11/106 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220186180 | Studer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York) |
| INVENTOR(S) | Lorenz Studer (New York, New York); Stuart M. Chambers (New York, New York); Yuchen Qi (New York, New York); Yvonne Marissa Mica (Danbury, Connecticut) |
| ABSTRACT | The present invention relates to the field of stem cell biology, in particular the linage specific differentiation of pluripotent or multipotent stem cells, which can include, but is not limited to, human embryonic stem cells (hESC), human induced pluripotent stem cells (hiPSC), somatic stem cells, cancer stem cells, or any other cell capable of lineage specific differentiation. Specifically described are methods to direct the lineage specific differentiation of hESC and/or hiPSC to nociceptors (i.e. nociceptor cells) using novel culture conditions. The nociceptors made using the methods of the present invention are further contemplated for various uses including, but limited to, use in in vitro drug discovery assays, pain research, and as a therapeutic to reverse disease of, or damage to, the peripheral nervous system (PNS). Further, compositions and methods are provided for producing melanocytes from human pluripotent stem cells for use in disease modeling. |
| FILED | Wednesday, December 22, 2021 |
| APPL NO | 17/559314 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/062 (20130101) Original (OR) Class C12N 5/0618 (20130101) C12N 5/0626 (20130101) C12N 2501/13 (20130101) C12N 2501/15 (20130101) C12N 2501/16 (20130101) C12N 2501/40 (20130101) C12N 2501/155 (20130101) C12N 2501/415 (20130101) C12N 2501/727 (20130101) C12N 2506/02 (20130101) C12N 2506/45 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5023 (20130101) G01N 33/5058 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220186184 | Good et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zinaida Good (Stanford, California); Garry P. Nolan (Stanford, California); Sean C. Bendall (Palo Alto, California); Evan Weber (Stanford, California); Crystal Mackall (Stanford, California) |
| ABSTRACT | The present disclosure generally relates to compositions and methods useful for an adoptive cell therapy. Some embodiments of the disclosure relates to methods for producing a population of lymphocytes enriched in T stem cell memory cells (TSCM cells). Further provided are compositions containing a substantially pure population of TSCM cells that are therapeutically effective in treating various cancers, and kits containing such compositions. Methods for treating a subject having or suspected of having a cancer using the compositions and kits as disclosed herein are also provided. |
| FILED | Thursday, January 10, 2019 |
| APPL NO | 16/960504 |
| CURRENT CPC | Peptides C07K 14/7051 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Original (OR) Class C12N 2503/02 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220186190 | Schook et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Lawrence B. Schook (Chicago, Illinois); Ron C. Gaba (Chicago, Illinois); Regina M. Schwind (Chicago, Illinois); Kyle Schachtschneider (Chicago, Illinois) |
| ABSTRACT | Genetically modified pigs having at least one cancer and/or at least one co-morbid condition are provided. Also provided are methods of using the pig and derived tumor cells to screen for therapeutic compounds, medical devices or procedures, and/or combinations thereof. Further provided are methods of producing personalized cancer models, including obtaining a tumor sample from a subject, identifying mutations in the tumor sample, and producing a genetically modified tumor or tumor cell line having the same mutations. |
| FILED | Tuesday, March 03, 2020 |
| APPL NO | 17/436441 |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) A01K 2207/00 (20130101) A01K 2217/05 (20130101) A01K 2217/203 (20130101) A01K 2227/108 (20130101) A01K 2267/0331 (20130101) A01K 2267/0381 (20130101) Fodder A23K 20/105 (20160501) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0693 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220186192 | Deng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York) |
| INVENTOR(S) | Liang Deng (New York, New York); Stewart Shuman (New York, New York); Ning Yang (New York, New York); Taha Merghoub (New York, New York); Jedd Wolchok (New York, New York) |
| ABSTRACT | Disclosed herein are methods and compositions related to the treatment, prevention, and/or amelioration of cancer in a subject in need thereof. In particular aspects, the present technology relates to the use of poxviruses, including a recombinant modified vaccinia Ankara (MVA) virus or vaccinia virus with deletion of vaccinia host-range factor C7 (MVAΔC7L and VACVΔC7L, respectively), alone or in combination with immune checkpoint blocking agents, as an oncolytic and immunotherapeutic composition. In some embodiments, the technology of the present disclosure relates to a MVAΔC7L or VACVΔC7L virus further modified to express human Fms-like tyrosine kinase 3 ligand (Flt3L). |
| FILED | Wednesday, December 29, 2021 |
| APPL NO | 17/565332 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/285 (20130101) A61K 2039/525 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 15/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220186218 | BAUER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts); UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| ASSIGNEE(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts); UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| INVENTOR(S) | Daniel E. BAUER (Cambridge, Massachusetts); Shuqian XU (Brookline, Massachusetts); Scot A. WOLFE (Winchester, Massachusetts); Kevin LUK (Worcester, Massachusetts) |
| ABSTRACT | Provided herein are ribonucleoprotein (RNP) complexes comprising a DNA-targeting endonuclease Cas (CRISPR-associated) protein and a guide RNA (gRNA) that that targets and hybridizes to the β-Globin gene. In one embodiment, the Cas protein is Cas9 and the gRNA comprises the sequence of SEQ ID NO: 1. In one embodiment, the Cas protein is Cas12a and the gRNA comprises the sequence of SEQ ID NO: 3. |
| FILED | Friday, January 24, 2020 |
| APPL NO | 17/425689 |
| CURRENT CPC | Peptides C07K 14/805 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/111 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220186226 | Mali et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Prashant Mali (La Jolla, California); Dhruva Katrekar (La Jolla, California) |
| ABSTRACT | Aspects of the disclosure relate to a gene therapy approach for diseases, disorders, or conditions caused by mutation in the stop codon utilizing modified tRNA. At least 10-15% of all genetic diseases, including muscular dystrophy (e.g. Duchene muscular dystrophy), some cancers, beta thalassemia, Hurler syndrome, and cystic fibrosis, fall into this category. Not to be bound by theory, it is believed that this approach is safer than CRISPR approaches due to minimal off-target effects and the lack of genome level changes. |
| FILED | Friday, March 04, 2022 |
| APPL NO | 17/687411 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/78 (20130101) C12N 15/115 (20130101) Original (OR) Class Enzymes C12Y 305/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220186260 | Boye et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Shannon E. Boye (Gainesville, Florida); William W. Hauswirth (Gainesville, Florida); Sanford L. Boye (Gainesville, Florida) |
| ABSTRACT | Disclosed are viral vector compositions comprising polynucleotide sequences that express one or more biologically-active mammalian guanylate cyclase proteins. Also disclosed are methods for their use in preventing, treating, and/or ameliorating at least one or more symptoms of a disease, disorder, abnormal condition, or dysfunction resulting at least in part from a guanylate cyclase deficiency in vivo. In particular embodiments, the use of recombinant adeno-associated viral (rAAV) vectors to treat or ameliorate symptoms of Leber's congenital amaurosis, as well as other conditions caused by an absence or reduction in the expression of a functional retinal-specific guanylate cyclase 1 (retGC1). |
| FILED | Wednesday, December 01, 2021 |
| APPL NO | 17/540121 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 48/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) C12N 15/86 (20130101) C12N 15/861 (20130101) Original (OR) Class Enzymes C12Y 406/01002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220186285 | Kwong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia); Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gabriel A. Kwong (Atlanta, Georgia); Andrew B. Adams (Atlanta, Georgia); Quoc Mac (Atlanta, Georgia); David V. Mathews (Atlanta, Georgia) |
| ABSTRACT | An activity-based nanosensor composition for detecting protease activity comprising a cleavable detectable substrate and methods of use are disclosed. |
| FILED | Thursday, January 13, 2022 |
| APPL NO | 17/574947 |
| CURRENT CPC | Peptides C07K 5/00 (20130101) C07K 7/00 (20130101) C07K 14/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/37 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/245 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220186301 | NGUYEN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Huy Quoc NGUYEN (Cambridge, Massachusetts); Shyamtanu CHATTORAJ (Cambridge, Massachusetts); George M. CHURCH (Cambridge, Massachusetts); Chao-ting WU (Cambridge, Massachusetts) |
| ABSTRACT | The technology described herein is directed to methods, systems, and compositions for analyzing, detecting, and/or visualizing target molecules. Described herein are compositions and systems comprising oligonucleotide tags comprising barcoded cassettes. Also described herein are methods for analyzing target molecules, the method comprising contacting a sample with at least one oligonucleotide tag, contacting the sample with at least two readout molecules, and detecting the relative spatial order of the readout molecules. |
| FILED | Thursday, July 30, 2020 |
| APPL NO | 17/631167 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6841 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220186311 | SZALLASI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Children's Medical Center Corporation (Boston, Massachusetts); The Technical University of Denmark (Lingby, Denmark); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts); The Technical University of Denmark (Lingby, Denmark); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Zoltan SZALLASI (Boston, Massachusetts); Nicolai Juul BIRKBAK (Københaven Ø, Denmark); Aron EKLUND (Københaven Ø, Denmark); Daniel SILVER (Wayland, Massachusetts); Zhigang WANG (Chestnut Hill, Massachusetts); Andrea RICHARDSON (Chestnut Hill, Massachusetts) |
| ABSTRACT | The present invention is based, in part, on the identification of novel methods for defining predictive biomarkers of response to anti-cancer drugs. |
| FILED | Tuesday, March 01, 2022 |
| APPL NO | 17/683656 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) Original (OR) Class C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/154 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220186401 | Kornberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Roger D. Kornberg (Atherton, California); Adrian Sanborn (Redwood City, California); Benjamin Yeh (Stanford, California) |
| ABSTRACT | Embodiments herein describe systems and methods to identify transcription factor activation domains and uses thereof. Many embodiments obtain activation measurements of tiles or segments of known transcription factors in an organism. Further embodiments train a machine learning model, such as a convolutional neural network, to identify transcription factors and activation domains in other organisms of the same or different species. Such methods and systems can be used for industrial, medical, and research purposes. |
| FILED | Wednesday, December 15, 2021 |
| APPL NO | 17/300935 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6811 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 30/04 (20130101) Original (OR) Class C40B 40/10 (20130101) Computer Systems Based on Specific Computational Models G06N 3/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220187181 | BARRETT et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona); inviCro, LLC (Boston, Massachusetts) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona); inviCro, LLC (Boston, Massachusetts) |
| INVENTOR(S) | Harrison H. BARRETT (Tucson, Arizona); Yijun DING (Tucson, Arizona); Luca CAUCCI (Tucson, Arizona); John William HOPPIN (Boston, Massachusetts) |
| ABSTRACT | The present invention provides autoradiography methods and systems for imaging via the detection of alpha particles, beta particles, or other charged particles. Embodiments of the methods and systems provide high-resolution 3D imaging of the distribution of a radioactive probe, such as a radiopharmaceutical, on a tissue sample. Embodiments of the present methods and systems provide imaging of tissue samples by reconstruction of a 3D distribution of a source of particles, such as a radiopharmaceutical. Embodiments of the methods and systems provide tomographic methods including microtomography, macrotomography, cryomicrotomography and cryomacrotomography. |
| FILED | Wednesday, October 20, 2021 |
| APPL NO | 17/506396 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/037 (20130101) A61B 6/4241 (20130101) A61B 6/4258 (20130101) A61B 6/5205 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 7/004 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/02 (20130101) G01N 15/0227 (20130101) Original (OR) Class Measurement of Nuclear or X-radiation G01T 1/2942 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220187190 | Higgins et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John M. Higgins (Cambridge, Massachusetts); Anwesha Chaudhury (Boston, Massachusetts) |
| ABSTRACT | Systems and methods for modeling and detecting white blood cell population dynamic for diagnosis and treatment, e.g., of acute coronary syndrome or leukocytosis. |
| FILED | Friday, March 04, 2022 |
| APPL NO | 17/687270 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1459 (20130101) Original (OR) Class G01N 33/49 (20130101) Information and Communication Technology [ICT] Specially Adapted for Specific Application Fields, Not Otherwise Provided for G16Z 99/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220187209 | OH et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Seungeun OH (Cambridge, Massachusetts); Marc KIRSCHNER (Cambridge, Massachusetts) |
| ABSTRACT | A method for measuring a composition of a biological sample is disclosed. A stimulated Raman scattering (SRS) image of the biological sample is received. The effect of light scattering in the received SRS image is computationally removed. An absolute concentration of total protein, total lipid, and/or water from the biological sample is determined. |
| FILED | Thursday, May 07, 2020 |
| APPL NO | 17/594353 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) Original (OR) Class G01N 33/68 (20130101) G01N 2021/655 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220187299 | Fong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lawrence Fong (Palo Alto, California); Serena Kwek MacPhee (San Francisco, California); Jera Lewis (San Francisco, California) |
| ABSTRACT | The disclosure provides methods of determining patient populations amenable or suitable for immunomodulatory treatment of disease such as cancer by measuring the relative or absolute levels of T-cell sub-populations correlated with disease such as cancer. |
| FILED | Monday, November 29, 2021 |
| APPL NO | 17/537308 |
| CURRENT CPC | Peptides C07K 16/2818 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/505 (20130101) G01N 33/574 (20130101) Original (OR) Class G01N 33/5743 (20130101) G01N 33/56972 (20130101) G01N 33/57407 (20130101) G01N 33/57434 (20130101) G01N 2333/70514 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220187309 | WHEELER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sarah E. WHEELER (Bellevue, Pennsylvania); Michael R. SHURIN (Wexford, Pennsylvania); Li LIU (Pittsburgh, Pennsylvania); UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania); UPMC (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sarah E. WHEELER (Bellevue, Pennsylvania); Michael R. SHURIN (Wexford, Pennsylvania); Li LIU (Pittsburgh, Pennsylvania) |
| ABSTRACT | Disclosed herein are compositions and uses thereof for detection of disease-related antibodies. The methods include contacting a biological sample with a solid support comprising one or more antigens that bind one or more therapeutic monoclonal antibodies, and detecting the disease-related antibody in the biological sample using an electrophoretic method. |
| FILED | Wednesday, April 29, 2020 |
| APPL NO | 17/607149 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/561 (20130101) G01N 33/6854 (20130101) Original (OR) Class G01N 2333/70596 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220187311 | Kuhn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Peter Kuhn (Solana Beach, California); Madelyn McCormick (Boston, Massachusetts); Anand Kolatkar (Los Angeles, California) |
| ABSTRACT | The disclosure provides methods for detecting circular endothelial cells (CECs) in a non-enriched blood sample. The present disclosure is based, in part, on the unexpected discovery that CECs can be detected in non-enriched blood samples. The present disclosure is further based, in part, on the discovery that CECs can be detected in non-enriched blood samples by combining the detection of one or more immunofluorescent markers in the nucleated cells of a non-enriched blood sample with an assessment of the morphology of the nucleated cells. The present disclosure is further based, in part, on the discovery that CECs can be detected in non-enriched blood samples by comparing the immunofluorescent marker staining and morphological characteristics of CECs with the immunofluorescent marker staining and morphological characteristics of WBCs. The methods disclosed herein serve to classify human subject in myocardial infarction (MI) patients or healthy controls. |
| FILED | Tuesday, August 10, 2021 |
| APPL NO | 17/398846 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6887 (20130101) Original (OR) Class G01N 2333/745 (20130101) G01N 2333/70503 (20130101) G01N 2333/70589 (20130101) G01N 2800/324 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220187315 | Kaddurah-Daouk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rima F. KADDURAH-DAOUK (Belmont, Massachusetts); John A. RUSH (Durham, North Carolina); Siamk Mahmoudian DEHKORDI (Durham, North Carolina); Sudeepa BHATTCHARYYA (Little Rock, Arkansas); Ranga R. KRISHNAN (Chicago, Illinois); Mark A. FRYE (Rochester, Minnesota); Ahmed T. AHMED (Rochester, Minnesota); Richard M. WEINSHILBOUM (Rochester, Minnesota); Boadie W. DUNLOP (Atlanta, Georgia); Wei JIA (Honolulu, Hawaii); Duke University (Durham, North Carolina); UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES (Little Rock, Arizona); RUSH MEDICAL COLLEGE (Chicago, Illinois); MAYO CLINIC (Rochester, Minnesota); EMORY UNIVERSITY SCHOOL OF MEDICINE (Atlanta, Georgia); UNIVERSITY OF HAWAII CANCER CENTER (Honolulu, Hawaii) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rima F. Kaddurah-Daouk (Belmont, Massachusetts); Augustus John Rush, Jr. (Durham, North Carolina); Siamak Mahmoudian Dehkordi (Durham, North Carolina); Sudeepa Bhattcharyya (Little Rock, Arkansas); Ranga R. Krishnan (Chicago, Illinois); Mark A. Frye (Rochester, Minnesota); Ahmed T. Ahmed (Rochester, Minnesota); Richard M. Weinshilboum (Rochester, Minnesota); Boadie W. Dunlop (Atlanta, Georgia); Wei Jia (Honolulu, None) |
| ABSTRACT | Described herein are methods and composition for diagnosing and evaluating the treatment of depression using one or more biomarker metabolites for the diagnosis and monitoring treatment efficacy. In one aspect, the biomarker metabolites can be used to screen subjects for the likelihood of developing depression, the diagnosis thereof, monitoring the efficacy of treatment, and evaluating a subject's propensity for responding to treatment. |
| FILED | Friday, March 06, 2020 |
| APPL NO | 17/438156 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/24 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) G01N 33/942 (20130101) G01N 33/6893 (20130101) Original (OR) Class G01N 2800/304 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220187321 | WORLEY et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cognext Diagnostics LLC (Baltimore, Maryland); The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul F. WORLEY (Baltimore, Maryland); Meifang XIAO (Lutherville-Timonium, Maryland); Desheng XU (Lutherville-Timonium, Maryland) |
| ABSTRACT | Disclosed herein are methods for diagnosing a subject as having a neurological disorder, such as Alzheimer's disease, using proximity-based detection assays capable of detecting complexes containing two or more synaptic proteins, such as neuronal pentraxins, from a blood, cerebrospinal fluid, or other fluid sample of the subject. Also disclosed are methods of evaluating and monitoring subjects having or at risk of developing a neurological disorder using the aforementioned assays. |
| FILED | Thursday, December 16, 2021 |
| APPL NO | 17/553173 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6851 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) Original (OR) Class G01N 2800/52 (20130101) G01N 2800/2814 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220187324 | Cummins et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brian Michael Cummins (Raleigh, North Carolina); Frances Smith Ligler (Raleigh, North Carolina); Glenn Walker (Raleigh, North Carolina) |
| ABSTRACT | Disclosed are methods and systems for determining concentrations of a target molecule and a variant thereof in a sample. The sample can comprise or be suspected to comprise a target molecule and at least one variant thereof and is exposed to one or more recognition elements that bind to the target molecule and/or the at least one variant. A signal is detected that is associated with the binding of the target molecule and/or a signal is detected that is associated with the binding of the at least one variant to the one or more recognition elements. The concentration of the target molecule and/or the at least one variant thereof is determined based on the signals. The system can comprise a receiver adapted to receive a sample comprising or suspected to comprise a target molecule and the at least one variant thereof, the receiver comprising one or more recognition elements that bind to one or more epitopes in the target molecule and/or the at least one variant thereof. |
| FILED | Tuesday, March 01, 2022 |
| APPL NO | 17/684296 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/74 (20130101) Original (OR) Class G01N 33/566 (20130101) G01N 33/6845 (20130101) G01N 2333/635 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220187405 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yong Wang (St. Louis, Missouri); Qing Wang (St. Louis, Missouri) |
| ABSTRACT | A computing device for diffusion dictionary imaging (DDI) of microstructure and inflammation of a patient is provided. The DDI computing device is connected to other computing devices, such as a magnetic resonance imaging (MRI) scanner. The DDI computing device receives magnetic resonance (MR) signals from the MRI scanner. Once received, the DDI computing device records the one or more MR signals to a memory device. The DDI computing device computationally processes the one or more MR signals to reconstruct a diffusion MRI image using diffusion dictionary data. The MR signals include values that are used as input to algorithms of the DDI data to reconstruct the diffusion MRI image. A database is used to store DDI data, artificial intelligence (AI) data, diffusion dictionary data, and MR data. |
| FILED | Wednesday, December 15, 2021 |
| APPL NO | 17/644433 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/414 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5608 (20130101) G01R 33/56341 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220187584 | Ha et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Taekjip Ha (Baltimore, Maryland); Jong-Chan Lee (Baltimore, Maryland); Ye Ma (Baltimore, Maryland) |
| ABSTRACT | The present invention is directed toward a system and method for STED nanography, which reduces background noise. To remove background noise from a STED image, the polarization of the STED beam is altered from that used to obtain the original image. A polarized image is obtained. This polarized image can then be subtracted from the original image to remove noise inherent to the image. |
| FILED | Thursday, March 26, 2020 |
| APPL NO | 17/598725 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) Optical Elements, Systems, or Apparatus G02B 21/008 (20130101) G02B 21/0068 (20130101) G02B 21/0072 (20130101) G02B 21/0076 (20130101) Original (OR) Class G02B 21/367 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220187586 | BROWN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Administrators of the Tulane Educational Fund (New Orleans, Louisiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathon Quincy BROWN (New Orleans, Louisiana); Samuel Jacob LEUTHY (New Orleans, Louisiana); Max Sebastian COOPER (New Orleans, Louisiana) |
| ABSTRACT | In order to remove the need for manual re-positioning of a sample (e.g., a tissue sample) on a microscope stage, systems and methods for sample positioning are described. A sample can be attached to a tissue positioning device. Then a microscope can be used to take a plurality of microscopy images (e.g., 2-dimensional, 3-dimensional, etc.) of a surface of the sample in a rotational geometry using the tissue positioning device to facilitate the microscopy. |
| FILED | Monday, April 20, 2020 |
| APPL NO | 17/603407 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 21/6458 (20130101) G01N 2021/6439 (20130101) Optical Elements, Systems, or Apparatus G02B 21/16 (20130101) G02B 21/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220187629 | Gulur et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Padma Gulur (Durham, North Carolina); Amanda Nelli (Durham, North Carolina) |
| ABSTRACT | The present disclosure describes a non-pharmacological analgesic approach using pain relieving effects of exposure to green-biased light spectrum. This green light effect is visually mediated and can be administered by exposing patients to the green-biased light spectrum by filtering ambient light. A therapeutic device is described in the form of green lensed eyeglasses and contact lenses that filter in the specific spectrum. |
| FILED | Wednesday, December 08, 2021 |
| APPL NO | 17/545502 |
| CURRENT CPC | Spectacles; Sunglasses or Goggles Insofar as They Have the Same Features as Spectacles; Contact Lenses G02C 7/04 (20130101) G02C 7/022 (20130101) G02C 7/102 (20130101) G02C 7/104 (20130101) Original (OR) Class G02C 2202/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220188671 | Jain et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vignet Incorporated (Fairfax, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Praduman Jain (Fairfax, Virginia); Dave Klein (Oakton, Virginia); Josh Schilling (Salem, Oregon) |
| ABSTRACT | Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for using machine learning to improve processes for achieving readiness. In some implementations, a database is accessed to obtain status data that indicates activities or attributes of a subject. One or more readiness scores indicating a level of capability of the subject to satisfy one or more readiness criteria are generated. Data is accessed indicating multiple candidate actions for improving capability of the subject to satisfy one or more readiness criteria. A subset of the candidate actions for the subject are selected based on the one or more readiness scores generated using the one or more models. Output is provided to cause one or more of the actions in the selected subset to be performed or cause an indication one or more of the actions in the selected subset to be presented on a user interface. |
| FILED | Friday, September 10, 2021 |
| APPL NO | 17/472232 |
| CURRENT CPC | Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 24/00 (20130101) Computer Systems Based on Specific Computational Models G06N 5/04 (20130101) Original (OR) Class G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220189041 | Cauley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen Cauley (Somerville, Massachusetts); Melissa Haskell (Cambridge, Massachusetts); Lawrence Wald (Cambridge, Massachusetts) |
| ABSTRACT | A combined physics-based and machine learning framework is used for reconstructing images from k-space data, in which motion artifacts are significantly reduced in the reconstructed images. In general, model-based retrospective motion correction techniques are accelerated using fast machine learning (“ML”) steps, which may be implemented using a trained neural network such as a convolutional neural network. In this way, the confidence of a classical physics-based reconstruction is obtained with the computational benefits of an ML-based network. |
| FILED | Thursday, March 26, 2020 |
| APPL NO | 17/442962 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 3/4046 (20130101) G06T 7/251 (20170101) Original (OR) Class G06T 2207/10088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20220184200 | BASLER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Atlanta, Georgia) |
| ASSIGNEE(S) | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Atlanta, Georgia) |
| INVENTOR(S) | Christopher F. BASLER (Atlanta, Georgia); JoAnn M. TUFARIELLO (Atlanta, Georgia); Lin WANG (Atlanta, Georgia) |
| ABSTRACT | Provided herein are virus-like particles and their uses for stimulating anti-pathogenic and anti-cancer immune responses. |
| FILED | Friday, March 20, 2020 |
| APPL NO | 17/441588 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/04 (20130101) A61K 39/12 (20130101) Original (OR) Class A61K 2039/5258 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/06 (20180101) A61P 31/14 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184428 | Tew |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Natick, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephanie M Tew (Salem, Virginia) |
| ABSTRACT | The disclosed subject matter relates to chemical and biological protective hood and garments including the hood. The hood includes a hood body having a face opening in the hood body, at least one section of a non-stretch protective composite fabric, at least one section of a stretch protective composite fabric and a face opening liner including a non-stretch fabric cover layer and an aerosol protective layer and does not include a vapor protective layer, the face opening liner being attached to the hood body and positioned around the perimeter of the face opening. |
| FILED | Friday, December 07, 2018 |
| APPL NO | 16/212751 |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 1/04 (20130101) A41D 13/11 (20130101) A41D 27/02 (20130101) A41D 2200/20 (20130101) Devices, Apparatus or Methods for Life-saving A62B 17/04 (20130101) Original (OR) Class A62B 17/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184442 | Dhau |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Molekule, Inc. (San Francisco, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jaspreet S. Dhau (San Francisco, California) |
| ABSTRACT | A firefighting system can include an aqueous solution, including an ionic liquid surfactant, and an application mechanism configured to disperse the solution toward a fire. |
| FILED | Monday, February 28, 2022 |
| APPL NO | 17/682991 |
| CURRENT CPC | Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus A62D 1/0021 (20130101) A62D 1/0042 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184587 | Porosoff et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Marc Porosoff (Washington, District of Columbia); Heather D. Willauer (Fairfax Station, Virginia) |
| ABSTRACT | A supported heterogeneous catalyst material for catalyzing the reverse water-gas shift (RWGS) reaction for the selective formation of CO using an alkali metal-doped molybdenum carbide on a gamma alumina support (A-Mo2C/γ-Al2O3, A=K, Na, Li). The A-Mo2C/γ-Al2O3 catalyst is synthesized by co-impregnation of molybdemun and alkali metal precursors onto a γ-Al2O3 support. It is then carburized to form the A-Mo2C/γ-Al2O3. |
| FILED | Monday, March 07, 2022 |
| APPL NO | 17/688645 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/02 (20130101) B01J 21/04 (20130101) B01J 27/22 (20130101) Original (OR) Class B01J 37/08 (20130101) B01J 37/084 (20130101) B01J 37/0201 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/40 (20170801) C01B 32/949 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184647 | Widener et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | South Dakota Board of Regents (Pierre, South Dakota) |
| ASSIGNEE(S) | South Dakota Board of Regents (Pierre, South Dakota); GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY (Washington, District of Columbia) |
| INVENTOR(S) | Christian Widener (Rapid City, South Dakota); Victor Champagne (Aberdeen Proving Ground, Maryland); Matthew Trexler (Aberdeen Proving Ground, Maryland); Dennis Helfritch (Aberdeen Proving Ground, Maryland); Rob Hrabe (Rapid City, South Dakota) |
| ABSTRACT | Cold spray devices and systems are disclosed. They include a flowpath having an inlet adapted for receiving communication with two or more inputs and an outlet adapted to discharge the two or more inputs. A discharge nozzle may be included in the flowpath of the outlet and a confluence may be included in the flowpath at the inlet for combining the two or more inputs. A nozzle body houses the discharge nozzle separate and downstream from the confluence of the two inputs. |
| FILED | Wednesday, March 02, 2022 |
| APPL NO | 17/684921 |
| CURRENT CPC | Spraying Apparatus; Atomising Apparatus; Nozzles B05B 7/1486 (20130101) B05B 7/1613 (20130101) B05B 7/1693 (20130101) Original (OR) Class Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 24/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184660 | Gong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Songbin Gong (Champaign, Illinois); Ruochen Lu (Austin, Texas) |
| ABSTRACT | A device includes a pair of substrate layer corresponding to a carrier substrate, an intermediary layer disposed on the pair of substrate layers, a cavity region disposed between the pair of substrate layers underneath the intermediary layer, a piezoelectric layer including a lithium-based film disposed on the intermediary layer, and a plurality of interdigital transducer electrodes disposed on the piezoelectric layer. The plurality of interdigital transducer electrodes includes an outer signal electrode, an inner signal electrode, an outer ground electrode and an inner ground electrode. |
| FILED | Wednesday, November 17, 2021 |
| APPL NO | 17/528438 |
| CURRENT CPC | Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/0603 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/22 (20130101) H01L 41/047 (20130101) H01L 41/1873 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220185231 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | US Gov't as represented by Secretary of Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Victor K. Lee (Monterey Park, California); Alexander I. Hess (Ebro, Florida); Lucas Van Epps (San Diego, California) |
| ABSTRACT | A vehicle, system, and method provide determining whether a thermal risk exists for an occupant of a passenger compartment of a vehicle based on: identifying, via the temperature sensor, that the temperature within the passenger compartment is outside of a safe temperature range, identifying, via an electronic control module, that an engine of the vehicle is not running, and identifying, via the occupant sensor, that an occupant is in the passenger compartment. In response to determining that the thermal risk exists, a controller starts starting the engine via an ignition locking system, closes power-actuated windows of the passenger compartment, locks power-locked doors of the passenger compartment, and activates a heating, ventilation and air conditioning system of the vehicle via a climate control unit. The HVAC maintains the temperature of the passenger compartment within the safe temperature range to safeguard the occupant until return of a responsible party. |
| FILED | Wednesday, January 06, 2021 |
| APPL NO | 17/142633 |
| CURRENT CPC | Arrangements of Heating, Cooling, Ventilating or Other Air-treating Devices Specially Adapted for Passenger or Goods Spaces of Vehicles B60H 1/00642 (20130101) Vehicles, Vehicle Fittings, or Vehicle Parts, Not Otherwise Provided for B60R 25/01 (20130101) Original (OR) Class B60R 25/24 (20130101) B60R 25/31 (20130101) Starting of Combustion Engines; Starting Aids for Such Engines, Not Otherwise Provided for F02N 11/087 (20130101) F02N 11/0803 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220185507 | Bernhardt |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul A. Bernhardt (Alexandria, Virginia) |
| ABSTRACT | A method and apparatus uses a VLF transmitter, a VLF receiver, and/or a low earth orbit satellite including a rocket engine. A VLF wave transmitted into space is converted to an ambient wave. The ambient wave acts as a signal wave for a whistler traveling wave parametric amplifier. Rocket exhaust is generated in atmospheric plasma. The rocket exhaust includes kinetic energy acting as a Lower Hybrid wave source. The Lower Hybrid wave source produces a Lower Hybrid wave, which acts as a pump wave for the parametric amplifier. Nonlinear mixing of the signal wave and the pump wave in the atmospheric plasma simultaneously parametrically amplifies the ambient wave and generates an idler wave and a parametrically amplified wave. The parametrically amplified wave (1) reduces the density of energetic protons or killer electrons in the Van Allen radiation belt, and (2) improves communications between the VLF transmitter and VLF receiver. |
| FILED | Friday, December 10, 2021 |
| APPL NO | 17/547457 |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/54 (20130101) B64G 1/242 (20130101) B64G 1/405 (20130101) Original (OR) Class Producing a Reactive Propulsive Thrust, Not Otherwise Provided for F03H 1/0081 (20130101) F03H 1/0087 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/4645 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220186190 | Schook et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Lawrence B. Schook (Chicago, Illinois); Ron C. Gaba (Chicago, Illinois); Regina M. Schwind (Chicago, Illinois); Kyle Schachtschneider (Chicago, Illinois) |
| ABSTRACT | Genetically modified pigs having at least one cancer and/or at least one co-morbid condition are provided. Also provided are methods of using the pig and derived tumor cells to screen for therapeutic compounds, medical devices or procedures, and/or combinations thereof. Further provided are methods of producing personalized cancer models, including obtaining a tumor sample from a subject, identifying mutations in the tumor sample, and producing a genetically modified tumor or tumor cell line having the same mutations. |
| FILED | Tuesday, March 03, 2020 |
| APPL NO | 17/436441 |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) A01K 2207/00 (20130101) A01K 2217/05 (20130101) A01K 2217/203 (20130101) A01K 2227/108 (20130101) A01K 2267/0331 (20130101) A01K 2267/0381 (20130101) Fodder A23K 20/105 (20160501) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0693 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220186276 | Jewett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael C. Jewett (Evanston, Illinois); Weston K. Kightlinger (Chicago, Illinois) |
| ABSTRACT | Disclosed are components, systems, and methods for glycoprotein protein synthesis in vitro and in vivo. In particular, the disclosed components, systems, and methods relate to modular platforms for producing glycoproteins. The components, systems, and methods disclosed herein may be used in synthesizing glycoproteins and recombinant glycoproteins in cell-free protein synthesis (CFPS) and in modified cells. |
| FILED | Friday, January 25, 2019 |
| APPL NO | 17/310191 |
| CURRENT CPC | Peptides C07K 1/1077 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/005 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220186915 | Ross et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | First-Light USA, LLC (Seymour, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeremy B. Ross (Monticello, Illinois); Blake S. Good (Urbana, Illinois); Jacob A. Flagle (New Palestine, Indiana) |
| ABSTRACT | A frame having a clip for securing the frame to an article of clothing or other object. The frame includes a mount for receiving a removable module and a rotatably attached clip. The clip includes an opening for accommodating sewing ribs between portions of a webbing and a gate (which may be a locking wire) moveable between an open position and a closed position at one end of the opening. In the open position, the locking wire removably engages one of a pair of elongated members defining the opening, e.g., by removably engaging that elongated member at a recess in an outside edge thereof, and does not obstruct the opening. When in the closed position, the locking wire removably engages the other of the elongated members, for example by removably engaging that other elongated member at a recess in its outside edge, and obstructs the longitudinal opening. |
| FILED | Wednesday, January 26, 2022 |
| APPL NO | 17/649055 |
| CURRENT CPC | Lighting Devices or Systems Thereof, Being Portable or Specially Adapted for Transportation F21L 4/027 (20130101) F21L 4/045 (20130101) Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for F21V 21/145 (20130101) F21V 21/0885 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses F21K, F21L, F21S and F21V, Relating to Uses or Applications of Lighting Devices or Systems F21W 2111/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220187133 | Zhou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Min Zhou (Atlanta, Georgia); Amirreza Keyhani (Atlanta, Georgia); Rong Yang (Atlanta, Georgia) |
| ABSTRACT | An embodiment provides a system for measuring temperature and deformation fields of at least a portion of a sample, comprising a visible light camera, an infrared camera, and a beam splitter. The visible light camera is at a first location with respect to the sample and can take a visible light image of at least a portion of the sample at a first time. The infrared camera is at a second location with respect to the sample and can take an infrared image of the at least a portion of the sample at the first time. The beam splitter can receive a beam of light, comprising infrared and visible light, traveling in a direction normal to the at least a portion of the sample and direct the infrared light to the infrared camera and the visible light to the visible light camera. |
| FILED | Tuesday, January 21, 2020 |
| APPL NO | 17/424845 |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/04 (20130101) G01J 5/80 (20220101) G01J 5/0859 (20130101) Original (OR) Class G01J 5/0875 (20130101) G01J 2005/0077 (20130101) Optical Elements, Systems, or Apparatus G02B 27/141 (20130101) Image Data Processing or Generation, in General G06T 7/80 (20170101) Pictorial Communication, e.g Television H04N 5/04 (20130101) H04N 5/2256 (20130101) H04N 17/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220187252 | JAURIQUI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vibrant Corporation (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Leanne JAURIQUI (Albuquerque, New Mexico); Thomas KOHLER (Diez, Germany); Alexander J. MAYES (Albuquerque, New Mexico); Julieanne HEFFERNAN (Albuquerque, New Mexico); Richard LIVINGS (Albuquerque, New Mexico); Eric BIEDERMANN (Albuquerque, New Mexico) |
| ABSTRACT | Creation and use of a digital twin instance (DTI) for a physical instance of the part. The DTI may be created by a model inversion process such that model parameters are iterated until a convergence criterion related to a physical resonance inspection result and a digital resonance inspection result is satisfied. The DTI may then be used in relation to part evaluation including through simulated use of the part. The physical instance of the part may be evaluated by way of the DTI or the DTI may be used to generate maintenance schedules specific to the physical instance of the part. |
| FILED | Wednesday, January 26, 2022 |
| APPL NO | 17/585299 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/04 (20130101) G01N 29/52 (20130101) G01N 29/4418 (20130101) Original (OR) Class Electric Digital Data Processing G06F 30/20 (20200101) G06F 2119/18 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220187675 | Buckwalter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James F. Buckwalter (Santa Barbara, California); Navid Hosseinzadeh (Goleta, California); Aditya Jain (Goleta, California); Roger Helkey (Santa Barbara, California) |
| ABSTRACT | A predistorter for an electro-optical converter includes a plurality of low noise RF amplifiers distributed along a transmission line that receive an RF input. Second order intermodulation injection (IM2) circuitry includes an inductively-degenerated frequency doubler to square and filter IM2 products of the RF input. A Mach-Zehnder Modulator (MZM) is used for electro-optical conversion. Feed forward circuitry injects IM2 to independently propagate RF intermodulation components with velocity matching to the MZM. At least one driver injects the RF input and RF intermodulation components into the MZM. |
| FILED | Tuesday, March 10, 2020 |
| APPL NO | 17/437979 |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/212 (20210101) G02F 1/2255 (20130101) Original (OR) Class Amplifiers H03F 1/32 (20130101) H03F 3/189 (20130101) H03F 2200/451 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220188393 | Forte et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Domenic J. Forte (Gainesville, Florida); Damon Woodard (Newberry, Florida); Fatemeh Ganji (Gainesville, Florida); Sumaiya Shomaji (Gainesville, Florida) |
| ABSTRACT | In general, embodiments of the present disclosure provide methods, apparatus, systems, computer program products, computing devices, computing entities, and/or the like for setting up biometric access for a legitimate user to a design. In accordance with various embodiments, a biometric template is received originating from the user and is inputted to a first secure sketch generator configured to use first transformation parameters comprising a hash function to generate a protected biometric template by hashing the biometric template. The protected biometric template is inputted to a second secure sketch generator configured to use second transformation parameters comprising a physical unclonable function serving as a fingerprint of the design to generate an original obfuscation key from the protected biometric template. The original obfuscation key is then used to obfuscate the design to generate an original bitstream, wherein the first and second transformation parameters and the original bitstream are stored on the design. |
| FILED | Tuesday, December 07, 2021 |
| APPL NO | 17/544453 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/32 (20130101) Original (OR) Class G06F 21/602 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0643 (20130101) H04L 9/3278 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220188486 | Matei et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ion Matei (Sunnyvale, California); Anne Plochowietz (Palo Alto, California); Saigopal Nelaturi (Mountain View, California); Johan de Kleer (Los Altos, California); Jeng Ping Lu (Fremont, California); Lara S. Crawford (Belmont, California); Eugene M. Chow (Palo Alto, California) |
| ABSTRACT | System and method that allow utilize machine learning algorithms to move a micro-object to a desired position are described. A sensor such as a high speed camera or capacitive sensing, tracks the locations of the objects. A dynamic potential energy landscape for manipulating objects is generated by controlling each of the electrodes in an array of electrodes. One or more computing devices are used to: estimate an initial position of a micro-object using the sensor; generate a continuous representation of a dynamic model for movement of the micro-object due to electrode potentials generated by at least some of the electrodes and use automatic differentiation and Gauss quadrature rules on the dynamic model to derive optimum potentials to be generated by the electrodes to move the micro-object to the desired position; and map the calculated optimized electrode potentials to the array to activate the electrodes. |
| FILED | Monday, December 14, 2020 |
| APPL NO | 17/121411 |
| CURRENT CPC | Electric Digital Data Processing G06F 30/17 (20200101) G06F 30/27 (20200101) Original (OR) Class G06F 2111/04 (20200101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220188491 | Kimura et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Adam Kimura (Lewis Center, Ohio); Rohan Prabhu (Dublin, Ohio); Noah Mun (Columbus, Ohio) |
| ABSTRACT | In an integrated circuit (IC) assessment method, an artificial intelligence (AI) component comprising at least one artificial neural network (ANN) is trained to transform layout rendering tiles of a rendering of a reference IC into corresponding reference layout image tiles extracted from at least one layout image of the reference IC. Using the trained AI component, standard cell layout renderings of a library of GDSII or OASIS standard cell layout renderings are transformed into as-fabricated standard cell layout renderings forming a library of as fabricated standard cell layout renderings. Instantiated standard cells and their placements in the layout image of an IC-under-test are identified by matching the instantiated standard cells with corresponding as-fabricated standard cell layout renderings retrieved from the library of as fabricated standard cell layout renderings. |
| FILED | Wednesday, December 08, 2021 |
| APPL NO | 17/545572 |
| CURRENT CPC | Electric Digital Data Processing G06F 30/327 (20200101) Original (OR) Class G06F 30/333 (20200101) G06F 30/392 (20200101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220188642 | RAJAPAKSE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Indika RAJAPAKSE (Ann Arbor, Michigan); Alfred HERO (Ann Arbor, Michigan); Alnawaz REHEMTULLA (Ann Arbor, Michigan); Ren WANG (Ann Arbor, Michigan); Stephen LINDSLY (Ann Arbor, Michigan) |
| ABSTRACT | The lack of robustness of Deep Neural Networks (DNNs) against different types of attacks is problematic in adversarial environments. The long-standing and arguably most powerful natural defense system is the mammalian immune system, which has successfully defended the species against attacks by novel pathogens for millions of years. This disclosure proposes a Robust Adversarial Immune-inspired Learning System (RAILS) inspired by the mammalian immune system. The RAILS approach is demonstrated using adaptive immune system emulation to harden Deep k-Nearest Neighbor (DkNN) architectures against evasion attacks. Using evolutionary programming to simulate new B-cell generation that occurs in natural immune systems, e.g., B-cell flocking, clonal expansion, and affinity maturation, it is shown that the RAILS learning curve exhibits similar learning behavior as observed in in-vitro experiments on B-cell affinity maturation. The life-long learning mechanism allows RAILS to evolve and defend against diverse attacks. |
| FILED | Wednesday, December 08, 2021 |
| APPL NO | 17/643290 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/086 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220189320 | MELODIA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tommaso MELODIA (Newton, Massachusetts); Lorenzo BERTIZZOLO (Boston, Massachusetts); Zhangyu GUAN (Chestnut Hill, Massachusetts); Salvatore D'ORO (Allston, Massachusetts) |
| ABSTRACT | Methods and systems are provided for controlling an unmanned aerial vehicle (UAV) swarm network including receiving, at a control terminal, an operator input defining a plurality of network performance directives, constructing a network control model representing the plurality of network performance directives, decomposing the network control model into a plurality of sub-models, generating, via the control terminal, a distributed UAV control model corresponding to each of the distributed sub-models, transmitting the generated distributed UAV control models to each of a plurality of UAVs of the UAV swarm network, executing, at each of the plurality of UAVs, at least one of the distributed UAV control models, and changing, responsive to the execution of the distributed UAV control models, an operating condition of at least one of the plurality of UAVs to satisfy the network performance directives. |
| FILED | Wednesday, February 12, 2020 |
| APPL NO | 17/603050 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/146 (20130101) Traffic Control Systems G08G 5/0013 (20130101) G08G 5/0026 (20130101) G08G 5/0043 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220190120 | Heller |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Eric Heller (Kettering, Ohio) |
| ABSTRACT | A gallium oxide field effect transistor that is built on a base layer. A doped gallium oxide channel layer is disposed on top of the base layer, and a dielectric barrier layer is disposed on top of the gallium oxide channel layer. Source contacts and drain contacts are disposed on top of the dielectric barrier layer, with one each of the drain contacts disposed in an interdigitated manner between one each of the source contacts. The interdigitated source contacts and drain contacts thereby define channels between them, where alternating ones of the channels are defined as odd channels, with even channels disposed therebetween. Gate contacts are disposed on top of the dielectric barrier layer in only one of the odd channels and the even channels. |
| FILED | Friday, March 04, 2022 |
| APPL NO | 17/686546 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/24 (20130101) Original (OR) Class H01L 29/0696 (20130101) H01L 29/41758 (20130101) H01L 29/42356 (20130101) H01L 29/66969 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220190123 | WONG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Joel C. WONG (Simi Valley, California); Jeong-Sun MOON (Malibu, California); Robert M. GRABAR (Malibu, California); Michael T. ANTCLIFFE (Malibu, California) |
| ABSTRACT | A method of fabricating a gate with a mini field plate includes forming a dielectric passivation layer over an epitaxy layer on a substrate, coating the dielectric passivation layer with a first resist layer, etching the first resist layer and the dielectric passivation layer to form a first opening in the dielectric passivation layer, removing the first resist layer; and forming a tri-layer gate having a gate foot in the first opening, the gate foot having a first width, a gate neck extending from the gate foot and extending for a length over the dielectric passivation layer on both sides of the first opening, the gate neck having a second width wider than the first width of the gate foot, and a gate head extending from the gate neck, the gate head having a third width wider than the second width of the gate neck. |
| FILED | Wednesday, March 02, 2022 |
| APPL NO | 17/684948 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/765 (20130101) H01L 21/28587 (20130101) H01L 21/31111 (20130101) H01L 21/31144 (20130101) H01L 29/205 (20130101) H01L 29/404 (20130101) Original (OR) Class H01L 29/413 (20130101) H01L 29/2003 (20130101) H01L 29/7786 (20130101) H01L 29/42316 (20130101) H01L 29/66462 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220190173 | Dressick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Walter J. Dressick (Waldorf, Maryland); Jasbinder S. Sanghera (Ashburn, Virginia); Woohong Kim (Washington, District of Columbia); Colin C. Baker (Alexandria, Virginia); Jason D. Myers (Alexandria, Virginia); Jesse A. Frantz (Washington, District of Columbia) |
| ABSTRACT | A composition of matter having a coated silicon substrate with multiple alternating layers of polydopamine and polyallylamine bound copper-indium-gallium oxide (CIGO) nanoparticles on the substrate. A related composition of matter having polyallylamine bound to CIGO nanoparticles to form PAH-coated CIGO nanoparticles. A related CIGO thin film made via conversion of layer-by-layer assembled CIGO nanoparticles and polyelectrolytes. CIGO nanoparticles are created via a flame-spray pyrolysis method using metal nitrate precursors, subsequently coated with polyallylamine (PAH), and dispersed in aqueous solution. Multilayer films are assembled by alternately dipping a substrate into a solution of either polydopamine or polystyrenesulfonate and then in the CIGO-PAH dispersion to fabricate CIGO films as thick as 1-2 microns. |
| FILED | Monday, March 07, 2022 |
| APPL NO | 17/688557 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02565 (20130101) H01L 21/02568 (20130101) H01L 21/02601 (20130101) H01L 21/02614 (20130101) H01L 21/02628 (20130101) H01L 31/18 (20130101) H01L 31/0322 (20130101) Original (OR) Class H01L 31/0352 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/541 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/50 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220190195 | Torres, JR. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Carlos Manuel Torres, JR. (San Diego, California); Brad Chun-Ting Liu (San Diego, California); Bienvenido Melvin L. Pascoguin (San Diego, California) |
| ABSTRACT | A method removes defects in a dielectric layer, such as during fabrication of a device that emits light from hot electrons injected into an atomically two-dimensional material. An atomically two-dimensional material and the dielectric layer are adjoined. The dielectric layer is adapted to convey a variable electric field for modulating a wavelength of photons electronically emitted across a band structure of the atomically two-dimensional material. Laser pulses are strobed into the dielectric layer with sufficient cumulative energy to remove a majority of the defects in the dielectric layer without altering the atomically two-dimensional material. |
| FILED | Wednesday, December 16, 2020 |
| APPL NO | 17/123306 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/06 (20130101) H01L 33/26 (20130101) H01L 33/42 (20130101) H01L 33/0093 (20200501) Original (OR) Class H01L 2933/0025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20220190383 — Electronic Connection in an All-Solid State Battery at the Anode/Electrolyte Interface
| US 20220190383 | Scanlon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lawrence G. Scanlon (Fairborn,, Ohio); William A Feld (Beavercreek, Ohio); Jacob W Lawson (Springfield, Ohio); Leah R Lucente (Beavercreek, Ohio) |
| ABSTRACT | The present invention relates to a solid-state battery that is based on a phthalocyanine solid-state electrolyte/anode connection that is chemically obtained. Such chemical connection process yields a solid electrolyte interphase that connects the solid-state battery's phthalocyanine solid-state electrolyte and anode. Unlike other processes for forming solid-state electrolyte/anode connections, the present chemical process does not require that solid-state electrolyte be ductile and flow under high pressure. |
| FILED | Friday, November 12, 2021 |
| APPL NO | 17/524794 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/058 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2220/30 (20130101) H01M 2300/0091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220190839 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhi Yang (Minneapolis, Minnesota); Anh Tuan Nguyen (Minneapolis, Minnesota); Diu Khue Luu (Minneapolis, Minnesota); Jian Xu (Minneapolis, Minnesota) |
| ABSTRACT | A digital-to-analog converter device including a set of components, each component included in the set of components including a number of unit cells, each unit cell being associated with a unit cell size indicating manufacturing specifications of the unit cell is provided by the present disclosure. The digital-to-analog converter device further includes a plurality of switches, each switch included in the plurality of switches being coupled to a component included in the set of components, and an output electrode coupled to the plurality of switches. The digital-to-analog converter device is configured to output an output signal at the output electrode. A first unit cell size associated with a first unit cell included in the set of components is different than a second unit cell size associated with a second unit cell included in the set of components. |
| FILED | Monday, March 07, 2022 |
| APPL NO | 17/687765 |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 1/007 (20130101) H03M 1/46 (20130101) Original (OR) Class H03M 1/447 (20130101) H03M 1/802 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220190877 | CHEN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); Wesleyan University (Middletown, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lei CHEN (College Park, Maryland); Steven Mark ANLAGE (Laurel, Maryland); Tsampikos KOTTOS (Middletown, Connecticut) |
| ABSTRACT | Systems, methods, and media for wireless power transfer are provided. In some embodiments, a system for wireless power transfer comprises: a processor communicatively coupled with a tuning element and a plurality of ports in an enclosure, the processor configured to cause the ports to generate electromagnetic radiation at a first frequency, set the tuning element to a first setting, acquire electromagnetic response from the ports, determine an S-matrix using the electromagnetic response, determine an eigenvalue of the S-matrix, repeat these steps (changing the first frequency and/or first setting) at least until the determined eigenvalue is approximately zero, determine a resolved electromagnetic radiation frequency and a resolved tuning element setting having the approximately zero eigenvalue, determine an eigenvector associated with the resolved electromagnetic radiation frequency and resolved tuning element setting, and cause the ports to generate the electromagnetic radiation at the resolved frequency with phase and amplitude determined from the eigenvector. |
| FILED | Tuesday, December 14, 2021 |
| APPL NO | 17/550915 |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/10 (20160201) H02J 50/20 (20160201) Transmission H04B 5/0037 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220190933 | Noh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Kyungjoo Noh (New Haven, Connecticut); Steven M. Girvin (Hamden, Connecticut); Liang Jiang (Guilford, Connecticut) |
| ABSTRACT | Systems and methods for performing bosonic quantum error correction (QEC) using Gottesman-Kitaev-Preskill (GKP) states are provided. An ancilla quantum mechanical oscillator is used to probe Gaussian noise experienced by a data quantum mechanical oscillator without disturbing the state of the data quantum mechanical oscillator. The ancilla quantum mechanical oscillator is initialized with a GKP state and entangled with the state of a data quantum mechanical oscillator to correlate any noise experienced by the data state with the state of the ancilla quantum mechanical oscillator. The states are then disentangled, and momentum and position quadrature operators of the ancilla quantum mechanical oscillator are measured and used to perform QEC on the information stored in the data quantum mechanical oscillator. |
| FILED | Friday, March 27, 2020 |
| APPL NO | 17/598148 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/40 (20220101) Transmission H04B 10/70 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220191149 | Brewer |
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| FUNDED BY |
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| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tony Brewer (Plano, Texas) |
| ABSTRACT | Implementations of the present disclosure are directed to systems and methods for reducing the size of packet headers without reducing the range of packet lengths supported. A packet header includes a fixed-width length field. Using a linear encoding, the maximum packet size is a linear function of the fixed-width length field. Thus, to expand the range of sizes available, either the granularity of the field must be decreased (e.g., by changing the measure of the field from flits to double-flits) or the size of the field must be increased (e.g., by changing the size of the field from 4 bits to 5 bits). However, by using a non-linear encoding, the difference between the minimum and maximum size can be increased without decreasing the granularity within a first range of field values and without increasing the size of the length field. |
| FILED | Wednesday, March 02, 2022 |
| APPL NO | 17/685073 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 45/74 (20130101) H04L 47/365 (20130101) Original (OR) Class H04L 49/109 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220191408 | Hairston et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Allen W. Hairston (Andover, Massachusetts); Thomas E. Collins III (Tyngsboro, Massachusetts) |
| ABSTRACT | A system for providing high resolution image output for pilotage and two color operation for threat detection, the system comprising a focal plane array, the focal plane array comprising: a plurality of pixels, wherein the pixels are arranged into groups of equal numbers of pixels, each pixel comprising: at least two detectors configured to receive electromagnetic energy; and a readout integrated circuit comprising an analog portion and a digital portion, which combine to form a current to frequency conversion circuit configured to convert current received from one of the at least two detectors into a pulse train, and a counter in operative communication with the frequency conversion circuit configured to count pulses in the pulse train during an integration time, wherein each detector from each of the pixels in a group of pixels is configured such that it can be connected to or disconnected from at least one detector from each adjacent pixel in a row or column from the same said group of pixels, and wherein each group of pixels is configured such that an output from detectors connected to one another is directed through the readout integrated circuit of a single pixel from the group of pixels. |
| FILED | Monday, December 14, 2020 |
| APPL NO | 17/120782 |
| CURRENT CPC | Pictorial Communication, e.g Television H04N 5/33 (20130101) Original (OR) Class H04N 5/378 (20130101) H04N 5/3651 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220191978 | Kessler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Metis Design Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Seth S. Kessler (Newton, Massachusetts); Gregory A. Thomas (San Francisco, California); Christopher T. Dunn (Salem, Massachusetts); Michael Borgen (Wilmington, Massachusetts); Brian L. Wardle (Lexington, Massachusetts) |
| ABSTRACT | A multifunctional assembly having a resistive element a conductive element in electrical communication with the resistive element, the conductive element defining at least one of a plurality of multifunctional zones of the resistive element, wherein the conductive element is configured to direct a flow of electricity across at least one of the plurality of multifunctional zones of the resistive element in a preselected manner. |
| FILED | Friday, January 14, 2022 |
| APPL NO | 17/576019 |
| CURRENT CPC | Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/04 (20130101) Resistors H01C 13/00 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 4/33 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 1/0236 (20130101) H05B 3/20 (20130101) H05B 3/145 (20130101) H05B 3/265 (20130101) H05B 3/267 (20130101) H05B 6/101 (20130101) Original (OR) Class H05B 2203/011 (20130101) H05B 2203/013 (20130101) H05B 2203/016 (20130101) H05B 2203/017 (20130101) H05B 2214/02 (20130101) H05B 2214/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220192005 | Bugeau-Medas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Jason M. Bugeau-Medas (Dover, New Hampshire); Scott P. Rogers (Nashua, New Hampshire); Eric A. Skogsholm (Merrimack, New Hampshire) |
| ABSTRACT | An electronic module utilizing a bathtub heatsink and single-cover design to provide improved thermal management and fault isolation while minimizing cost and complexity. The electronic module may also provide for better galvanic corrosion prevention through the utilization of a single finish on the components thereof. Further provided may be an electronic module design utilizing a single set of fasteners, which may further reduce assembly cost and complexity while further providing increase galvanic corrosion prevention. |
| FILED | Wednesday, December 16, 2020 |
| APPL NO | 17/123517 |
| CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0209 (20130101) Original (OR) Class H05K 3/282 (20130101) H05K 3/284 (20130101) H05K 2201/10409 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220192066 | Zaghloul et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Combat Capabilities Development Command, Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Amir I. Zaghloul (Bethesda, Maryland); Quang Minh Nguyen (Severn, Maryland); Eric D. Adler (Columbia, Maryland) |
| ABSTRACT | A highly-conformal, pliable thin electromagnetic (EM) skin for altering at least one electromagnetic property of a surface includes a pliable thin film, and sub-wavelength elements incorporated into and/or on the pliable thin film which are smaller in scale than the wavelengths of electromagnetic radiation they are intended to influence. The electromagnetic skin readily conforms to contours of a surface to which it attaches or otherwise adheres to. Such electromagnetic skin can be used to cover various surface and platforms on equipment, walls, vehicles, and aircraft to change the electromagnetic properties of such surfaces to achieve certain functions that are not achievable with simple ground plane surfaces. The EM skin may be judiciously configured to alter at least one electromagnetic property of the surface by blocking, absorbing, enhancing, and/or bending waves of electromagnetic radiation. |
| FILED | Wednesday, December 16, 2020 |
| APPL NO | 17/123902 |
| CURRENT CPC | Windows, Windscreens, Non-fixed Roofs, Doors, or Similar Devices for Vehicles; Removable External Protective Coverings Specially Adapted for Vehicles B60J 11/00 (20130101) Aeroplanes; Helicopters B64C 21/10 (20130101) B64C 2230/12 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 9/0081 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20220183589 | Karlicek, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York) |
| ASSIGNEE(S) | RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York) |
| INVENTOR(S) | Robert F. Karlicek, Jr. (Mechanicville, New York); Richard J. Radke (Slingerlands, New York); Arunas Tuzikas (Troy, New York); Claire F. Karlicek (Mechanicville, New York) |
| ABSTRACT | One embodiment provides a sensor module for patient monitoring. The sensor module includes a processor circuitry; a memory circuitry; at least one time of flight (TOF) sensor; a TOF logic; and a monitor logic. The TOF logic is configured to determine a sequence of elevation maps of at least a portion of a patient room. The TOF logic is further configured to at least one of a distance vector and a velocity vector associated with a selected room occupant based, at least in part, on a plurality of elevation maps in the sequence of elevation maps. Each elevation map is determined based, at least in part, on a respective TOF data set captured from the at least one TOF sensor. Each TOF data set is captured, periodically at a time interval. The monitor logic is configured to classify an activity of the selected room occupant as acceptable or unacceptable. The classifying is based, at least in part, on the at least one of the distance vector and the velocity vector. |
| FILED | Monday, March 30, 2020 |
| APPL NO | 17/598986 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0077 (20130101) A61B 5/1113 (20130101) Original (OR) Class A61B 5/1128 (20130101) A61B 5/6889 (20130101) A61B 5/7267 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/58 (20130101) G01S 17/89 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220183933 | FLOREZ et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| ASSIGNEE(S) | |
| INVENTOR(S) | FERNANDO LUIS ESTEBAN FLOREZ (Moore, Oklahoma); SHARUKH SOLI KHAJOTIA (Edmond, Oklahoma); ADAM JUSTIN RONDINONE (Knoxville, Tennessee) |
| ABSTRACT | A titanium dioxide (TiO2) composition and methods of use, the composition containing surface-modified doped TiO2 nanoparticles (sm-TiO2 NPs) disposed in a polymer matrix material, wherein each sm-TiO2 NP has an outer surface having a plurality N of bifunctional linker molecules attached thereto and a plurality of protein molecules linked to the sm-TiO2 NP via the bifunctional linker molecules; and wherein the polymer matrix comprises a polymer precursor component. |
| FILED | Wednesday, March 18, 2020 |
| APPL NO | 17/441869 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 6/69 (20200101) A61K 6/84 (20200101) Original (OR) Class A61K 6/884 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184552 | Voskian et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Sahag Voskian (Cambridge, Massachusetts); Trevor Alan Hatton (Sudbury, Massachusetts) |
| ABSTRACT | The present disclosure generally relates to apparatuses, systems, and methods for separating a target species (e.g., CO2) from a gas mixture (e.g., gas stream) via an electrochemical process. |
| FILED | Wednesday, March 02, 2022 |
| APPL NO | 17/685285 |
| CURRENT CPC | Separation B01D 53/326 (20130101) Original (OR) Class B01D 2257/504 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184557 | Jang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gyoung Gug Jang (Oak Ridge, Tennessee); Michael Z. Hu (Oak Ridge, Tennessee); Constantinos Tsouris (Oak Ridge, Tennessee) |
| ABSTRACT | A solar-thermal vapor-permeation membrane is provided. The solar-thermal vapor-permeation membrane includes a thermally conductive, microporous support layer having a feed surface, and an active separation layer adjacent the feed surface of the support layer. The support layer is capable of absorbing solar-thermal radiation. Utilization of solar energy for a membrane separation process replaces fossil-fuel derived energy with renewable energy as the driving force and does not involve the generation of undesirable greenhouse gas emissions. Therefore, the solar-thermal vapor-permeation process using the provided membrane is cost effective, energy efficient, and environmentally friendly. |
| FILED | Wednesday, December 08, 2021 |
| APPL NO | 17/545104 |
| CURRENT CPC | Separation B01D 61/362 (20130101) Original (OR) Class B01D 67/0079 (20130101) B01D 69/02 (20130101) B01D 69/10 (20130101) B01D 69/148 (20130101) B01D 71/021 (20130101) B01D 2323/04 (20130101) B01D 2323/30 (20130101) B01D 2325/38 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/14 (20130101) C02F 1/448 (20130101) C02F 2101/34 (20130101) C02F 2201/009 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184580 | Sunkara et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Advanced Energy Materials, LLC (Louisville, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mahendra Sunkara (Louisville, Kentucky); Sivakumar Vasireddy (Louisville, Kentucky); Juan He (Louisville, Kentucky) |
| ABSTRACT | The present invention is a method for removing sulfur from liquid hydrocarbon feedstocks and for performing hydrogenation reactions in sulfur-contaminated feedstocks, including the hydrogenation of naphthalene in the presence of sulfur compounds, using catalysts or adsorbents comprising metal oxide nanowires decorated with reduced catalytically-active metal particles. In a preferred embodiment, the adsorbent comprises zinc oxide nanowires decorated with catalytically-active metals selected from nickel, cobalt, molybdenum, platinum, palladium, copper, oxides thereof, alloys thereof, and combinations thereof. In some embodiments, the sulfur is removed through a desulfurization process without an external hydrogen supply. The process is effective for the removal of sulfur from diesel fuels and liquid fuel streams, and for deep desulfurization of natural gas streams. The process is also effective for the selective hydrogenation of naphthalene to tetralin in the presence of sulfur compounds. |
| FILED | Friday, February 18, 2022 |
| APPL NO | 17/675769 |
| CURRENT CPC | Separation B01D 19/0005 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/06 (20130101) B01J 20/08 (20130101) B01J 20/12 (20130101) B01J 20/3078 (20130101) B01J 20/3085 (20130101) B01J 20/28007 (20130101) B01J 20/28023 (20130101) Original (OR) Class B01J 23/755 (20130101) B01J 23/883 (20130101) B01J 35/0013 (20130101) B01J 37/08 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 25/003 (20130101) C10G 29/04 (20130101) C10G 29/16 (20130101) C10G 2300/202 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184585 | GRIFFIN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Brandon GRIFFIN (Denver, Colorado); Matthew Maurice YUNG (Denver, Colorado) |
| ABSTRACT | Described herein are catalysts and methods for converting waste biogas (e.g., a mixture of carbon dioxide and methane) into useful products. In some embodiments, the biogas is converted into a highly purified methane, that can be further processed to generate fuel products, including recycled natural gas (RNG) and liquid fuels. The described catalysts and methods may be advantageous over conventional methods, including by reducing catalyst costs, decreasing temperature requirements and/or providing higher purity products by reducing carbon dioxide and carbon monoxide in product streams. |
| FILED | Wednesday, December 15, 2021 |
| APPL NO | 17/551968 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/063 (20130101) B01J 23/10 (20130101) B01J 23/755 (20130101) Original (OR) Class Acyclic or Carbocyclic Compounds C07C 1/12 (20130101) C07C 2521/06 (20130101) C07C 2523/10 (20130101) C07C 2523/755 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184588 | Zhao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xianhui Zhao (Oak Ridge, Tennessee); James W. Klett (Oak Ridge, Tennessee); Soydan Ozcan (Oak Ridge, Tennessee); Halil Tekinalp (Oak Ridge, Tennessee); Justin Figley (Oak Ridge, Tennessee) |
| ABSTRACT | A method of forming a catalyst is provided herein. The method comprises combining a binder, a support, and an active metal to form a slurry composition. The method further comprises applying the slurry composition using an additive manufacturing process to form a green part. The method further comprises exposing the green part to heat at a temperature of from about 10° C. to about 150° C. to form the hardened part. The method further comprises applying a ceramic-based coating material to the hardened part to form the catalyst. |
| FILED | Monday, December 14, 2020 |
| APPL NO | 17/120408 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/04 (20130101) B01J 29/072 (20130101) Original (OR) Class B01J 33/00 (20130101) B01J 37/0018 (20130101) B01J 37/082 (20130101) B01J 37/0217 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/112 (20170801) B29C 64/165 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 40/20 (20200101) B33Y 70/10 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184702 | Hua et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bin Hua (Ammon, Idaho); Meng Li (Ammon, Idaho); Dong Ding (Idaho Falls, Idaho) |
| ABSTRACT | A method of forming a metal nanomaterial comprises forming a precursor solution comprising a metal precursor and a metal oxide precursor. A complexing agent is added to the precursor solution, and the metal precursor and the metal oxide precursor are hydrolyzed to form a sol. The sol is heated to form a gel, which is calcined to incorporate metal cations from the metal precursor into a metal oxide lattice from the metal oxide precursor. The calcined gel is exposed to a reducing agent to exsolve the metal from the metal oxide lattice and to form a metal nanomaterial comprising a metal and a metal oxide is formed. Additional methods of forming a metal nanomaterial are also disclosed. |
| FILED | Monday, August 23, 2021 |
| APPL NO | 17/445687 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 9/26 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220185693 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jianlin Li (Oak Ridge, Tennessee); Yaocai Bai (Oak Ridge, Tennessee); Mengya Li (Oak Ridge, Tennessee); David Wood (Oak Ridge, Tennessee) |
| ABSTRACT | An improved method of forming a transition metal layered oxide material for alkali-ion battery cathodes include combining an alkali-containing precursor and at least one transition metal precursor or other metal precursor at a low temperature of less than 100° C. to form a liquid eutectic alloy mixture. The mixture is then heated at a temperature between 300° C. to 500° C. to pre-calcinate the mixture, and subsequently the pre-calcinated mixture is subjected to a final calcination at a temperature of 500° C. to 1000° C. to obtain a crystalline oxide material. A P2-type or O3-type cathode may be formed with the layered oxide material, and a sodium-ion battery cell may include the so-formed P2-type or O3-type cathode. |
| FILED | Monday, December 13, 2021 |
| APPL NO | 17/548838 |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 49/0072 (20130101) C01G 53/40 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/049 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220185730 | Skoptsov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | H QUEST VANGUARD, INC. (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | George L. Skoptsov (Pittsburgh, Pennsylvania); Kurt W. Zeller (Pittsburgh, Pennsylvania); Aayush Mantri (Pittsburgh, Pennsylvania); Vignesh Viswanathan (Pittsburgh, Pennsylvania) |
| ABSTRACT | A nanocarbon material includes agglomerate nanostructures made of aggregates of: (i) graphene nanostructures having at least partially crumpled morphology, and (ii) clusters of at least one carbon material. The carbon material may have a graphitic structure. At least a portion of the graphitic structure may be at least partially hollow and have at least one winged protrusion. Optionally, the nanocarbon material may be part of a composition that includes a dispersion medium or a cementitious material. Methods of making such a composition are also disclosed. |
| FILED | Thursday, March 12, 2020 |
| APPL NO | 17/437616 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/194 (20170801) C01B 32/336 (20170801) C01B 2204/22 (20130101) C01B 2204/32 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/02 (20130101) C01P 2004/04 (20130101) C01P 2004/34 (20130101) C01P 2004/50 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 20/0036 (20130101) Original (OR) Class C04B 28/08 (20130101) C04B 2103/408 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 7/18 (20130101) Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black; C09C 1/44 (20130101) Alloys C22C 14/00 (20130101) C22C 32/0084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220185748 | GUNNOE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia); THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thomas B. GUNNOE (Palmyra, Virginia); John T. GROVES (Princeton, New Jersey); William A. GODDARD, III (Pasadena, California) |
| ABSTRACT | In one aspect, the disclosure relates to a method for functionalizing hydrocarbons. In a further aspect, the method involves heating a hydrocarbon with a composition having an acid and an oxidant. In other aspects, the composition can further include an iodine-based compound and/or a compound having formula AaXn. In any of these aspects, the oxidant can be regenerated in situ or in a separate regeneration step. Also disclosed are functionalized hydrocarbons produced by the disclosed method. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure. |
| FILED | Friday, March 13, 2020 |
| APPL NO | 17/438091 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 17/10 (20130101) Original (OR) Class C07C 29/095 (20130101) C07C 67/035 (20130101) C07C 201/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220186035 | Mass et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Boise State University (Boise, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Olga A. Mass (Boise, Idaho); William B. Knowlton (Boise, Idaho) |
| ABSTRACT | DNA has been employed to template dyes into controllable networks of dyes. However, dye-DNA constructs involving covalent tethering often suffer from the lack of structural rigidity due to DNA structural effects (e.g., DNA breathing). Moreover, attachment of a dye to DNA might result in more pronounced structural effects and loss of DNA structural integrity. Employing a dye as a nucleic acid crosslink will reduce deficiencies in DNA structural integrity by creating more rigid, stable, and robust dye-DNA networks while retaining the photophysical benefits of the desired dyes. The utilization of dye crosslinks offers a controllable spacing and orientation of dyes leading to a greater variety in the design of DNA-templated dye networks. Tetrapyrrole type dyes are of a particular interest. A notable chemical diversity of synthetic photo- and chemically stable tetrapyrroles with a variable substitution pattern allows fine-tuning of their chemical and photophysical properties within DNA-templated dye network. |
| FILED | Thursday, December 16, 2021 |
| APPL NO | 17/644620 |
| CURRENT CPC | Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 67/0063 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 10/20 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220186053 | Bukovsky |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eric Bukovsky (Livermore, California) |
| ABSTRACT | According to one aspect of an inventive concept, an ink includes a nonradiation-curable pre-polymer having at least two nonradiation-curable components per molecule of the nonradiation-curable pre-polymer, a radiation-curable component, a polymer having at least one reactive hydrogen component, and a photoinitiator. A concentration of the nonradiation-curable pre-polymer having at least two nonradiation-curable components is in a range of greater than 0 weight % to less than 99 weight % of a total weight of the ink. |
| FILED | Thursday, May 30, 2019 |
| APPL NO | 17/440091 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/106 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/10 (20130101) C08G 18/672 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/101 (20130101) Original (OR) Class C09D 11/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220186120 | Mundoor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Haridas Mundoor (Boulder, Colorado); Ivan I. Smalyukh (Boulder, Colorado) |
| ABSTRACT | Composite condensed matter material, devices including the composite condensed matter material, and methods of forming and using the composite condensed matter material are disclosed. The composite condensed matter material includes a host material and particles dispersed and suspended within the host material. The composite condensed matter material can exhibit one or more low symmetry phases and reconfigurable properties. |
| FILED | Friday, December 10, 2021 |
| APPL NO | 17/548388 |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 19/52 (20130101) Original (OR) Class C09K 2019/521 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220186343 | Detrois et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Martin Detrois (Salem, Oregon); Paul D. Jablonski (Salem, Oregon); Jeffrey A. Hawk (Salem, Oregon) |
| ABSTRACT | Nickel alloys, methods of making nickel alloys, articles including the nickel alloys, uses of the alloys, and methods of treating nickel alloys are described. The inventive heat resistant structural materials are suitable for applications requiring high yield stress at room temperature and good creep strength at high temperatures, such as in gas turbines, steam turbines, fossil energy boilers, aero engines, power generation systems using fluids such as supercritical carbon dioxide (e.g., advanced ultra-supercritical power plants), concentrated solar power plants, nuclear power plants, molten salt reactors: turbine blades, casings, valves, heat exchangers and recuperators. |
| FILED | Wednesday, October 27, 2021 |
| APPL NO | 17/511594 |
| CURRENT CPC | Alloys C22C 19/055 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220186550 | Fleury et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Blaise Fleury (Boulder, Colorado); Ivan I. Smalyukh (Boulder, Colorado); Jan Bart ten Hove (Boulder, Colorado); Vladyslav Cherpak (Westminster, Colorado); Eldho Abraham (Boulder, Colorado); Taewoo Lee (Broomfield, Colorado); Bohdan Senyuk (Boulder, Colorado) |
| ABSTRACT | Insulated assemblies, insulation units including an assembly, and methods of forming the assemblies and units are disclosed. Exemplary assemblies include a first pane of material, a second pane of material, and one or more monolithic insulating layers interposed between the first pane of material and the second pane of material. The insulating layer can exhibit a thermal conductivity less than 26 mW/(K.m). |
| FILED | Friday, December 10, 2021 |
| APPL NO | 17/548127 |
| CURRENT CPC | Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 3/6715 (20130101) Original (OR) Class E06B 3/67326 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220186565 | Kontras |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Evan A. Kontras (Kansas City, Missouri) |
| ABSTRACT | A shrouded screw apparatus includes an outer tube, a telescoping inner tube, an auger bit, and an anti-rotation pin. The outer tube has a first sidewall defining a first interior chamber. The first sidewall has an opening defined therethrough. The inner tube is positioned in the first interior chamber. The inner tube has a second sidewall defining a second interior chamber. The second sidewall has a longitudinal groove defined therein. The inner tube is configured to extend from and retract within the first interior chamber of the outer tube. The auger bit is positioned in the second interior chamber and is rotatably coupled to the inner tube. The anti-rotation pin is coupled to the first sidewall of the outer tube and extends inwardly into the first interior chamber. The pin engages the longitudinal groove of the inner tube. |
| FILED | Thursday, December 10, 2020 |
| APPL NO | 17/118109 |
| CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 10/22 (20130101) Original (OR) Class E21B 10/44 (20130101) E21B 10/62 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220186947 | Boetcher et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Embry-Riddle Aeronautical University, Inc. (Daytona Beach, Florida); UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sandra Kathleen Sparr Boetcher (New Smyrna Beach, Florida); Kashif Nawas (Oak Ridge, Tennessee); Melissa Ann Messenger (Yulee, Florida); Casey Josh Troxler (Edgewater, Maryland); Thomas Benjamin Freeman (Carthage, North Carolina); Rafael M. Rodriguez (Ormond Beach, Florida) |
| ABSTRACT | A thermal energy storage heat exchanger can include a core defining a plurality of airflow passages to receive an airstream therethrough. The core can be made of a composite of a phase change material shape-stabilized by a polymer. The phase change material can be structurally supported by the polymer and the phase change material can be configured to change phases to store energy from and deliver stored energy to the airstream when the airflow passes through the core. |
| FILED | Wednesday, December 15, 2021 |
| APPL NO | 17/551524 |
| CURRENT CPC | Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 5/0021 (20130101) Original (OR) Class F24F 13/30 (20130101) F24F 2005/0032 (20130101) F24F 2110/10 (20180101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 20/023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220188155 | Miniskar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Narasinga Rao Miniskar (Oak Ridge, Tennessee); Frank Y. Liu (Oak Ridge, Tennessee); Aaron R. Young (Oak Ridge, Tennessee); Jeffrey S. Vetter (Oak Ridge, Tennessee); Dwaipayan Chakraborty (Oak Ridge, Tennessee) |
| ABSTRACT | Apparatus and methods are disclosed for scheduling tasks in a heterogeneous computing environment. Coarse scheduling of a received task-set is performed centrally, with tasks dispatched to respective processing resources including one or more accelerators. At each accelerator, sub-tasks of a received task are identified, scheduled, and executed. Data-transfer and computation sub-tasks can be pipelined. The accelerator operates using small tiles of local data, which are transferred to or from a large shared reservoir of main memory. Sub-task scheduling can be customized to each accelerator; coarse task scheduling can work on larger tasks; both can be efficient. Simulations demonstrate large improvements in makespan and/or circuit area. Disclosed technologies are scalable and can be implemented in varying combinations of hard-wired or software modules. These technologies are widely applicable to high-performance computing, image classification, media processing, wireless coding, encryption, and other fields. |
| FILED | Friday, December 03, 2021 |
| APPL NO | 17/542022 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/4881 (20130101) Original (OR) Class G06F 9/5016 (20130101) G06F 9/5027 (20130101) G06F 2209/501 (20130101) G06F 2209/5017 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220188185 | SeyedzadehDelcheh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | SeyedMohammad SeyedzadehDelcheh (Bellevue, Washington); Sergey Blagodurov (Bellevue, Washington) |
| ABSTRACT | An apparatus and method for efficiently transmitting data are described. A transmitter sends data to a receiver. An encoder of the transmitter divides a received first block of data into multiple sub-blocks. The encoder selects a portion of each sub-block to compare to one another. A portion in a particular sub-block has a same offset and a same size as other portions of other sub-blocks. If the encoder determines the multiple portions match one another, the encoder sends, to the receiver, a second block of data corresponding to the first block of data. The second block of data has a same size as a size of the received first block of data, and the second block of data includes security data from one of multiple error correction schemes. Therefore, the second block of data provides security without increasing an amount of data to transmit. |
| FILED | Thursday, December 10, 2020 |
| APPL NO | 17/118434 |
| CURRENT CPC | Electric Digital Data Processing G06F 11/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220188474 | Snyder et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Isabelle B. Snyder (Oak Ridge, Tennessee); Nils M. Stenvig (Oak Ridge, Tennessee); Travis M. Smith (Oak Ridge, Tennessee) |
| ABSTRACT | A method for associating geographic location information with a power system model. The method generally includes the steps of receiving known geographic information for a plurality of power system assets within the model and automatically calculating the geographic information for other power system assets with unknown geographic information based on the imported geographic information and architectural information available within the model. The step of calculating the geographic location information may be performed iteratively initially using only imported geographic information and subsequently using both imported and calculated geographic information. The geographic location of each power system asset with an unknown location may be determined through multilateration based on known locations and branch connection lengths of two or more connections with known geolocations. |
| FILED | Wednesday, December 08, 2021 |
| APPL NO | 17/545010 |
| CURRENT CPC | Electric Digital Data Processing G06F 16/29 (20190101) G06F 30/18 (20200101) Original (OR) Class G06F 2113/06 (20200101) Image Data Processing or Generation, in General G06T 11/206 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220189648 | van Rooyen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Isabella J. van Rooyen (Idaho Falls, Idaho); Youssef A. Ballout (Idaho Falls, Idaho) |
| ABSTRACT | A nuclear fuel rod comprises a nuclear fuel material, a material surrounding the nuclear fuel material, and cladding surrounding the material, the material forming a fuel-cladding gap between the nuclear fuel material and the cladding. Related nuclear fuel rods and methods are also disclosed. |
| FILED | Friday, December 10, 2021 |
| APPL NO | 17/643628 |
| CURRENT CPC | Nuclear Reactors G21C 3/06 (20130101) Original (OR) Class G21C 3/18 (20130101) G21C 3/047 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220190179 | Sewell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SunPower Corporation (San Jose, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard Hamilton Sewell (Los Altos, California); David Aaron Randolph Barkhouse (Oakland, California); Douglas Rose (Vista, California); Lewis Abra (San Francisco, California) |
| ABSTRACT | Wire-based metallization and stringing techniques for solar cells, and the resulting solar cells, modules, and equipment, are described. In an example, a substrate has a surface. A plurality of N-type and P-type semiconductor regions is disposed in or above the surface of the substrate. A conductive contact structure is disposed on the plurality of N-type and P-type semiconductor regions. The conductive contact structure includes a plurality of conductive wires, each conductive wire of the plurality of conductive wires essentially continuously bonded directly to a corresponding one of the N-type and P-type semiconductor regions. |
| FILED | Monday, December 06, 2021 |
| APPL NO | 17/543438 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/188 (20130101) H01L 31/0516 (20130101) Original (OR) Class H01L 31/02013 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220190191 | ALBIN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); Bowling Green State University (Bowling Green, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Scott ALBIN (Denver, Colorado); Marco NARDONE (Bowling Green, Ohio); Gregory Frank PACH (Denver, Colorado) |
| ABSTRACT | Disclosed herein are CdSeTe photovoltaic devices having interdigitated back contact architecture for use in polycrystalline thin films in photovoltaic devices. |
| FILED | Friday, April 03, 2020 |
| APPL NO | 17/599851 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/073 (20130101) H01L 31/1832 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220190356 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Buffalo, New York); Giner, Inc. (Newton, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gang Wu (Clarence Center, New York); Hui Xu (Acton, Massachusetts); Shengwen Liu (Buffalo, New York); Shuo Ding (Boston, Massachusetts) |
| ABSTRACT | Atomically dispersed platinum-group metal-free catalyst and method for synthesizing the same. According to one embodiment, the catalyst is made by a method in which, in a first step, a metal oxide/zeolitic imidazolate frameworks (ZIF) composite is formed by combining (i) nanoparticles of an oxide of at least one of iron, cobalt, nickel, manganese, and copper, (ii) a hydrated zinc salt, and (iii) an imidazole. Then, in a second step, the metal oxide/ZIF composite is thermally activated, i.e., carbonized, to form an M-N—C catalyst. Thereafter, the M-N—C catalyst may be mixed with a quantity of ammonium chloride, and then the M-N—C/NH4Cl mixture may be pyrolyzed. The foregoing NH4Cl treatment may improve the intrinsic activity of the catalyst. Then, a thin layer of nitrogen-doped carbon may be added to NH4Cl-treated M-N—C catalyst by chemical vapor deposition (CVD). Such CVD treatment may improve the stability of the catalyst. |
| FILED | Friday, November 19, 2021 |
| APPL NO | 17/531461 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/9016 (20130101) H01M 4/9075 (20130101) Original (OR) Class H01M 2008/1095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220190364 | Saraidaridis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Technologies Corporation (Waltham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James D. Saraidaridis (Hartford, Connecticut); Zhiwei Yang (South Windsor, Connecticut) |
| ABSTRACT | A method for maintaining a redox flow includes draining a first battery electrolyte solution from a redox flow battery cell, the cell including a separator layer arranged between a first electrode and a second electrode, a first circulation loop configured to provide the first battery electrolyte solution to the first electrode and a second circulation loop configured to provide a second battery electrolyte solution to the second electrode; and flowing a non-battery electrolyte solution through the first electrode. The non-battery electrolyte removes at least a portion of the solid precipitates from at least one of the first electrode and the separator layer. The method also includes draining the non-battery electrolyte solution from the cell and returning the first battery electrolyte solution to the cell. A method for a redox flow battery and a redox flow battery are also disclosed. |
| FILED | Friday, December 11, 2020 |
| APPL NO | 17/119408 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/188 (20130101) H01M 8/04186 (20130101) Original (OR) Class H01M 8/04201 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220190629 | Varigonda et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cummins Inc. (Columbus, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Subbarao Varigonda (Columbus, Indiana); Jaroslaw Leonarski (Columbus, Indiana); Harsha R. Ademane (Indianapolis, Indiana) |
| ABSTRACT | A mild-hybrid energy storage system architecture is provided, comprising: a battery; an ultracapacitor connected in parallel with the battery; a passive battery pre-charge circuit connected between a terminal of the battery and a DC bus; a battery main contactor connected in parallel with the battery pre-charge circuit between the terminal of the battery and the DC bus; a passive ultracapacitor pre-charge circuit connected between a terminal of the ultracapacitor and the DC bus; an ultracapacitor main contactor connected in parallel with the ultracapacitor pre-charge circuit between the terminal of the ultracapacitor and the DC bus; and a control module configured to independently control operation of the battery pre-charge circuit, the battery main contactor, the ultracapacitor pre-charge circuit and the ultracapacitor main contactor. |
| FILED | Thursday, January 23, 2020 |
| APPL NO | 17/433116 |
| CURRENT CPC | Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles B60K 6/28 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/44 (20130101) H01M 10/0525 (20130101) H01M 2220/20 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/345 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220190638 | Raju |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ravisekhar Nadimpalli Raju (Clifton Park, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ravisekhar Nadimpalli Raju (Clifton Park, New York) |
| ABSTRACT | A system and method is provided to provide power to a load or electronic equipment which includes a multi-pole switch that connects the input of the load or electronic equipment to a first AC source or a DC source or an optional second AC source created from the DC source through a DC-AC converter. The connection to the DC source is either direct or through a DC-DC converter that provides voltage adjustment or isolation. A controller changes the position of the switch in response to the sensing of the presence and magnitude of the sources or in response to an external command to select a preferred source. |
| FILED | Wednesday, March 02, 2022 |
| APPL NO | 17/685330 |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 9/061 (20130101) H02J 9/062 (20130101) H02J 9/068 (20200101) Original (OR) Class Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220191246 | Edgar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| ASSIGNEE(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| INVENTOR(S) | Thomas W. Edgar (Richland, Washington); Draguna L. Vrabie (West Richland, Washington); William J. Hofer (Richland, Washington); Kathleen E. Nowak (Richland, Washington) |
| ABSTRACT | Methods are described for protecting a cyber-physical system against a potential attacker of the system. The methods include a method of generating a plurality of examples for a training data set and training a system model using the training data set to generate a decoy configured to generate a synthetic output that mimics historical outputs generated by the system for a given historical system context. Also described is a method including receiving a system context of a cyber-physical system; receiving an inquiry into the system by a potential attacker; applying a system model to the system context and the inquiry; obtaining from the system model a synthetic output that mimics how a component of the system would respond to the inquiry given the system context; and providing the synthetic output to the potential attacker. |
| FILED | Wednesday, March 02, 2022 |
| APPL NO | 17/684873 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/0445 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1416 (20130101) H04L 63/1491 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220192024 | Wielandt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stijn Wielandt (Berkeley, California); Baptiste Dafflon (Berkeley, California) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus related to printed circuit boards. In one aspect, a device includes a first board and a second board. The first board includes at least two pins defined at an end of the first board. The first pin and the second pin are positioned along a first line and parallel to the first line. The second board includes at least two slots defined at an end of the second board. The first slot and the second slot are positioned along a second line and are angled from the second line by about ±10° to 15° . Each of the pins in the first board is engaged with each of the slots in the second board and forms an electrical connection between the first pin and the first slot and the second pin and the second slot. |
| FILED | Monday, December 06, 2021 |
| APPL NO | 17/543032 |
| CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/119 (20130101) H05K 1/181 (20130101) Original (OR) Class H05K 2201/10151 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20220183280 | Veleva |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BENANOVA INC. (Cary, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anka Veleva (Cary, North Carolina) |
| ABSTRACT | Disclosed is a method for creating a composite colloidal particle formulation with advanced functionality that possesses highly efficient and effective properties. The composite colloidal particle formulation comprises an engineered biodegradable particle core dispersed in a bioadhesive polyelectrolyte solution. Also disclosed are methods of use of the same, including but not limited to applying said formulation to plants for disease treatment. |
| FILED | Thursday, December 16, 2021 |
| APPL NO | 17/644745 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/04 (20130101) A01N 25/10 (20130101) A01N 25/22 (20130101) Original (OR) Class A01N 59/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220183326 | Sheth et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Imvela Corp. (Brooklyn, New York) |
| ASSIGNEE(S) | Imvela Corp. (Brooklyn, New York) |
| INVENTOR(S) | Ravi Sheth (Brooklyn, New York); Kendall Dabaghi (Brooklyn, New York); Felix Ekenss (Brooklyn, New York); Miriam Shiffman (Pittsburgh, Pennsylvania) |
| ABSTRACT | Provided herein are fermented beverages comprising symbiotic microbial communities, and methods of production thereof. |
| FILED | Friday, March 04, 2022 |
| APPL NO | 17/687563 |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 2/382 (20130101) Original (OR) Class A23L 33/135 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220183589 | Karlicek, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York) |
| ASSIGNEE(S) | RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York) |
| INVENTOR(S) | Robert F. Karlicek, Jr. (Mechanicville, New York); Richard J. Radke (Slingerlands, New York); Arunas Tuzikas (Troy, New York); Claire F. Karlicek (Mechanicville, New York) |
| ABSTRACT | One embodiment provides a sensor module for patient monitoring. The sensor module includes a processor circuitry; a memory circuitry; at least one time of flight (TOF) sensor; a TOF logic; and a monitor logic. The TOF logic is configured to determine a sequence of elevation maps of at least a portion of a patient room. The TOF logic is further configured to at least one of a distance vector and a velocity vector associated with a selected room occupant based, at least in part, on a plurality of elevation maps in the sequence of elevation maps. Each elevation map is determined based, at least in part, on a respective TOF data set captured from the at least one TOF sensor. Each TOF data set is captured, periodically at a time interval. The monitor logic is configured to classify an activity of the selected room occupant as acceptable or unacceptable. The classifying is based, at least in part, on the at least one of the distance vector and the velocity vector. |
| FILED | Monday, March 30, 2020 |
| APPL NO | 17/598986 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0077 (20130101) A61B 5/1113 (20130101) Original (OR) Class A61B 5/1128 (20130101) A61B 5/6889 (20130101) A61B 5/7267 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/58 (20130101) G01S 17/89 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220183990 | Guan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhibin Guan (Irvine, California); Dongchu Yang (Irvine, California); Alexander Eldredge (Irvine, California) |
| ABSTRACT | The disclosure provides for peptide-functionalized biodegradable polymers, and methods of using the polymers for efficiently delivering RNAs of various sizes, and secondary structures inside cells. |
| FILED | Friday, February 21, 2020 |
| APPL NO | 17/432077 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/4841 (20130101) A61K 9/5146 (20130101) Original (OR) Class A61K 31/713 (20130101) A61K 31/7105 (20130101) A61K 47/59 (20170801) A61K 47/6455 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184197 | Scott et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Evan A. Scott (Northfield, Illinois); Chyung-Ru Wang (Evanston, Illinois); Shaobin Shang (Evanston, Illinois); Dina Kats (Evanston, Illinois) |
| ABSTRACT | Provided herein are subunit vaccine compositions comprising a nanocarrier and a lipid antigen, a peptide antigen or combinations thereof that elicit bother a CD1-restricted and an MHC-restricted T cell response in a subject. Methods for making and using the subunit vaccine compositions are also provided. |
| FILED | Monday, December 20, 2021 |
| APPL NO | 17/645288 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/51 (20130101) A61K 39/04 (20130101) Original (OR) Class A61K 2039/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184224 | RINALDI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | CARLOS RINALDI (Gainesville, Florida); SUN HAO (Gainesville, Florida); BRENT S. SUMERLIN (Gainesville, Florida) |
| ABSTRACT | Embodiments of the present disclosure provide for magnetic particle conjugates, methods of making the magnetic particle conjugates, methods of using magnetic particle conjugates, micelles (also referred to as a “magnetic composite nanocarrier” (MCNC)), methods of making micelles, methods of using micelles, and the like. |
| FILED | Monday, March 07, 2022 |
| APPL NO | 17/653733 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/52 (20170801) A61K 47/60 (20170801) A61K 47/6907 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220184803 | Guerin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Kelleher Guerin (Baltimore, Maryland); Gregory D. Hager (Baltimore, Maryland) |
| ABSTRACT | System and methods to create an immersive virtual environment using a virtual reality system that receives parameters corresponding to a real-world robot. The real-world robot may be simulated to create a virtual robot based on the received parameters. The immersive virtual environment may be transmitted to a user. The user may supply input and interact with the virtual robot. Feedback such as the current state of the virtual robot or the real-world robot may be provided to the user. The user may train the virtual robot. The real-world robot may be programmed based on the virtual robot training. |
| FILED | Friday, March 04, 2022 |
| APPL NO | 17/687409 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1605 (20130101) Original (OR) Class B25J 9/1671 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 2219/40131 (20130101) G05B 2219/45097 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/05 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220185675 | King et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WiSys Technology Foundation, Inc. (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Seth Thomas King (Holmen, Wisconsin); Daniel John Little (Onalaska, Wisconsin) |
| ABSTRACT | Various embodiments provide a zinc oxide graphene composite. A zinc oxide graphene composite includes zinc oxide crystallites and graphene. A method of forming the composite includes combining graphene and zinc oxalate to form a mixture and heating the mixture to produce the zinc oxide graphene composite. |
| FILED | Wednesday, April 01, 2020 |
| APPL NO | 17/594087 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/194 (20170801) Original (OR) Class C01B 2204/22 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/60 (20130101) C01P 2002/72 (20130101) C01P 2002/82 (20130101) C01P 2002/85 (20130101) C01P 2004/03 (20130101) C01P 2004/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220185828 | Toutov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anton Toutov (Magnolia, Texas); Kerry Betz (Boulder, Colorado); Alexey Fedorov (Wallisellen, Switzerland); Brian M. Stoltz (San Marino, California); Wenbo Liu (Pasadena, California); Robert H. Grubbs (South Pasadena, California) |
| ABSTRACT | The present disclosure describes methods for silylating aromatic derivatives, comprising the use of hydrosilanes and potassium hydroxide. |
| FILED | Monday, March 07, 2022 |
| APPL NO | 17/688122 |
| CURRENT CPC | Heterocyclic Compounds C07D 209/12 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/0801 (20130101) Original (OR) Class C07F 7/0827 (20130101) C07F 7/0832 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220185950 | Veige et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Adam S. Veige (Gainesville, Florida); Vineet K. Jakhar (Gainesville, Florida) |
| ABSTRACT | Provided herein are catalysts for polymerization of alkenes to cyclic poly(alkenes), and methods of making and using the same. |
| FILED | Thursday, April 30, 2020 |
| APPL NO | 17/607522 |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 11/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/08 (20130101) Original (OR) Class C08G 2261/418 (20130101) C08G 2261/3324 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220186116 | BRGOCH et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | University of Houston System (Houston, Texas) |
| INVENTOR(S) | Jakoah BRGOCH (Houston, Texas); Shruti HARIYANI (Houston, Texas) |
| ABSTRACT | Provided herein are phosphors of the general molecular formula: (A2-2xEux(Mg1-yCay)PO4F wherein the variables are as defined herein. Methods of producing the phosphors are also provided. In some aspects, the present disclosure provides light-emitting devices comprising these phosphors. |
| FILED | Friday, November 19, 2021 |
| APPL NO | 17/530924 |
| CURRENT CPC | Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 17/10 (20200101) C01F 17/30 (20200101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2006/60 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/7739 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/502 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220186285 | Kwong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia); Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gabriel A. Kwong (Atlanta, Georgia); Andrew B. Adams (Atlanta, Georgia); Quoc Mac (Atlanta, Georgia); David V. Mathews (Atlanta, Georgia) |
| ABSTRACT | An activity-based nanosensor composition for detecting protease activity comprising a cleavable detectable substrate and methods of use are disclosed. |
| FILED | Thursday, January 13, 2022 |
| APPL NO | 17/574947 |
| CURRENT CPC | Peptides C07K 5/00 (20130101) C07K 7/00 (20130101) C07K 14/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/37 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/245 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220186380 | Chan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Candace Chan (Phoenix, Arizona); Jon Mark Weller (Phoenix, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Candace Chan (Phoenix, Arizona); Jon Mark Weller (Phoenix, Arizona) |
| ABSTRACT | Forming a lithium lanthanum zirconate thin film includes disposing zirconium oxide on a substrate to yield a zirconium oxide coating, contacting the zirconium oxide coating with a solution including a lithium salt and a lanthanum salt, heating the substrate to yield a dried salt coating on the zirconium oxide coating, melting the dried salt coating to yield a molten salt mixture, reacting the molten salt mixture with the zirconium oxide coating to yield lithium lanthanum zirconate, and cooling the lithium lanthanum zirconate to yield a lithium lanthanum zirconate coating on the substrate. In some cases, the zirconium oxide coating is contacted with an aqueous molten salt mixture including a lithium salt and a lanthanum salt, the molten salt mixture is reacted with the zirconium oxide coating to yield lithium lanthanum zirconate, and the lithium lanthanum zirconate is cooled to yield a lithium lanthanum zirconate coating on the substrate. |
| FILED | Thursday, March 03, 2022 |
| APPL NO | 17/685923 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/405 (20130101) C23C 16/45555 (20130101) C23C 18/1216 (20130101) C23C 18/1295 (20130101) C23C 22/05 (20130101) C23C 22/70 (20130101) Original (OR) Class C23C 28/042 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0562 (20130101) H01M 2300/0077 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220186947 | Boetcher et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Embry-Riddle Aeronautical University, Inc. (Daytona Beach, Florida); UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sandra Kathleen Sparr Boetcher (New Smyrna Beach, Florida); Kashif Nawas (Oak Ridge, Tennessee); Melissa Ann Messenger (Yulee, Florida); Casey Josh Troxler (Edgewater, Maryland); Thomas Benjamin Freeman (Carthage, North Carolina); Rafael M. Rodriguez (Ormond Beach, Florida) |
| ABSTRACT | A thermal energy storage heat exchanger can include a core defining a plurality of airflow passages to receive an airstream therethrough. The core can be made of a composite of a phase change material shape-stabilized by a polymer. The phase change material can be structurally supported by the polymer and the phase change material can be configured to change phases to store energy from and deliver stored energy to the airstream when the airflow passes through the core. |
| FILED | Wednesday, December 15, 2021 |
| APPL NO | 17/551524 |
| CURRENT CPC | Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 5/0021 (20130101) Original (OR) Class F24F 13/30 (20130101) F24F 2005/0032 (20130101) F24F 2110/10 (20180101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 20/023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220187153 | Gruebele et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexander M. Gruebele (Stanford, California); Andrew C. Zerbe (Woodside, California); Margaret M. Coad (Stanford, California); Mark R. Cutkosky (Palo Alto, California) |
| ABSTRACT | A distributed sensor network for soft growing robots is provided. Sensor bands are distributed at discrete intervals along the length of the flexible tube, and the sensor bands each are wrapped circumferentially around the diameter of the flexible tube. Each sensor band has one or more sensors and one or more semi-rigid islands containing a self-contained microcontroller, and one or more communication lines to an aggregator microcontroller located at the base of the soft growing robot communicatively connecting signals from the sensor bands. A casing laminates the distributed sensor network. In one example the encasing has cavities or a tooth geometry to allow bending. The casing is flexible to not hinder the growth of the soft growing robot, yet protecting the distributed sensor network. |
| FILED | Friday, December 10, 2021 |
| APPL NO | 17/548130 |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 3/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220187185 | Grover et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents Of The University Of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | William H. Grover (Riverside, California); Brittney A. McKenzie (Riverside, California) |
| ABSTRACT | A method for of validating the identity of one of more component(s) in a substance including: obtaining a substance; placing the substance in a plenum with a sealed bottom; exposing the substance to a perturbation; digitally recoding the time-dependent changes in the substance after exposing the substance to the perturbation; producing a chronological fingerprint of the changes, where the chronological fingerprint is a digital multi-dimensional image of the changes as a function of time; and comparing the chronological fingerprint to chronological fingerprints for known substances to validate the one or more component(s) in the substance being measured. Also described are associated systems and computer program products for implementing the method. |
| FILED | Tuesday, March 17, 2020 |
| APPL NO | 17/593337 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 3/502761 (20130101) B01L 2300/0654 (20130101) B01L 2300/1894 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/14 (20130101) Original (OR) Class Image or Video Recognition or Understanding G06V 10/62 (20220101) G06V 10/761 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220187391 | Chen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | University of Houston System (Houston, Texas) |
| INVENTOR(S) | Ji Chen (Sugar Land, Texas) |
| ABSTRACT | In an embodiment, the present disclosure pertains to electric field generators that include a signal generator electrically connected to a power amplifier, a impedance matching circuit electrically connected to the power amplifier, and a power divider electrically connected to the impedance matching circuit and to at least one of a first wall, a second wall, a third wall, a fourth wall, or a base area. In an additional embodiment, the present disclosure pertains to method of determining radio frequency (RF)-induced heating on a medical device utilizing an electric field generator of the present disclosure. Additional embodiments of the present disclosure pertain to methods of making electric field generators for testing a medical device. |
| FILED | Monday, December 13, 2021 |
| APPL NO | 17/549503 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/00 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/288 (20130101) Original (OR) Class Amplifiers H03F 3/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220188415 | Mishra et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Prabhat Kumar Mishra (Gainesville, Florida); Zhixin Pan (Gainesville, Florida) |
| ABSTRACT | The present disclosure provides systems and methods for test pattern generation to detect a hardware Trojan. One such method includes determining, by a computing device, a set of initial test patterns to activate the hardware Trojan within an integrated circuit design; evaluating nodes of the integrated circuit design and assigning a rareness attribute value and a testability attribute value associated with respective nodes of the integrated circuit design; and generating a set of additional test patterns to activate the hardware Trojan within the integrated circuit design using a reinforcement learning model. The set of initial test patterns is applied as an input along with rareness attribute values and testability attribute values associated with the nodes of the integrated circuit, and the reinforcement learning model is trained with a stochastic learning scheme to identify optimal test patterns for triggering nodes of the integrated circuit design. |
| FILED | Tuesday, December 07, 2021 |
| APPL NO | 17/543940 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/554 (20130101) Original (OR) Class G06F 2221/034 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220188600 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The George Washington University (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jiajun Li (Arlington, Virginia); Ahmed Louri (Vienna, Virginia) |
| ABSTRACT | Systems and methods are disclosed for a centrosymmetric convolutional neural network (CSCNN), an algorithm/hardware co-design framework for CNN compression and acceleration that mitigates the effects of computational irregularity and effectively exploits computational reuse and sparsity for increased performance and energy efficiency. |
| FILED | Wednesday, December 15, 2021 |
| APPL NO | 17/551967 |
| CURRENT CPC | Electric Digital Data Processing G06F 7/5443 (20130101) Computer Systems Based on Specific Computational Models G06N 3/063 (20130101) G06N 3/0454 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220188613 | LI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The George Washington University (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jiajun LI (Arlington, Virginia); Ahmed LOURI (Vienna, Virginia) |
| ABSTRACT | We introduce SGCNAX, a scalable GCN accelerator architecture for the high-performance and energy-efficient acceleration of GCNs. Unlike prior GCN accelerators that either employ limited loop optimization techniques, or determine the design variables based on random sampling, we systematically explore the loop optimization techniques for GCN acceleration and provide a flexible GCN dataflow that adapts to different GCN configurations to achieve optimal efficiency. We further provide two hardware-based techniques to address the workload imbalance problem caused by the unbalanced distribution of zeros in GCNs. Specifically, SGCNAX exploits an outer-product-based computation architecture that mitigates the intra-PE (Processing Elements) workload imbalance, and employs a group-and-shuffle approach to mitigate the inter-PE workload imbalance. |
| FILED | Wednesday, December 15, 2021 |
| APPL NO | 17/551876 |
| CURRENT CPC | Electric Digital Data Processing G06F 7/5443 (20130101) Computer Systems Based on Specific Computational Models G06N 3/063 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220188996 | Zhou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina); RAMONA OPTICS INC. (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kevin Zhou (Durham, North Carolina); Colin Cooke (Durham, North Carolina); Jaehee Park (Durham, North Carolina); Ruobing Qian (Durham, North Carolina); Roarke Horstmeyer (Durham, North Carolina); Joseph Izatt (Durham, North Carolina); Sina Farsiu (Durham, North Carolina) |
| ABSTRACT | A method of mesoscopic photogrammetry can be carried out using a set of images captured from a camera on a mobile computing device. Upon receiving the set of images, the method generates a composite image, which can include applying homographic rectification to warp all images of the set of images onto a common plane; applying a rectification model to undo perspective distortion in each image of the set of images; and applying an undistortion model for adjusting for camera imperfections of a camera that captured each image of the set of images. A height map is generated co-registered with the composite image, for example, by using an untrained CNN whose weights/parameters are optimized in order to optimize the height map. The height map and the composite image can be output for display. |
| FILED | Friday, December 10, 2021 |
| APPL NO | 17/547731 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/002 (20130101) G06T 5/006 (20130101) G06T 5/50 (20130101) Original (OR) Class G06T 2207/20084 (20130101) G06T 2207/20221 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220189041 | Cauley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen Cauley (Somerville, Massachusetts); Melissa Haskell (Cambridge, Massachusetts); Lawrence Wald (Cambridge, Massachusetts) |
| ABSTRACT | A combined physics-based and machine learning framework is used for reconstructing images from k-space data, in which motion artifacts are significantly reduced in the reconstructed images. In general, model-based retrospective motion correction techniques are accelerated using fast machine learning (“ML”) steps, which may be implemented using a trained neural network such as a convolutional neural network. In this way, the confidence of a classical physics-based reconstruction is obtained with the computational benefits of an ML-based network. |
| FILED | Thursday, March 26, 2020 |
| APPL NO | 17/442962 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 3/4046 (20130101) G06T 7/251 (20170101) Original (OR) Class G06T 2207/10088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220189579 | Si et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Dong Si (Seattle, Washington); Jonas Pfab (Seattle, Washington); Nhut Minh Phan (Seattle, Washington) |
| ABSTRACT | In some embodiments, a method of determining a molecular structure of a protein is provided. A computing system receives voxel data representing electron density obtained via cryo-electron microscopy. The computing system uses one or more neural networks to predict one or more likelihoods for each voxel. The computing system determines a backbone structure based on the predicted likelihoods. The computing system maps amino acid sequences to the backbone structure based on the predicted likelihoods. Mapping the amino acid sequences to the backbone structure based on the predicted likelihoods includes conducting an alignment technique that uses a reward function and a gap penalty. The computing system determines locations of carbon, nitrogen, and oxygen atoms within the backbone structure based on the predicted likelihoods. The computing system determines side-chain atoms based on the predicted backbone structure and the amino acid sequences to complete the molecular structure. |
| FILED | Friday, December 10, 2021 |
| APPL NO | 17/548342 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/42 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 15/00 (20190201) Original (OR) Class G16B 30/10 (20190201) G16B 40/20 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220190226 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | Choongho Yu (College Station, Texas); Yufan Zhang (College Station, Texas) |
| ABSTRACT | A hydro-electrochemical power generator includes an interlayer having a first end and a second end opposite the first end, a first electrode in contact with the first end of the interlayer, wherein the first electrode includes a first material that is a corrodible metallic material, a second electrode in contact with the second end of the interlayer, wherein the second electrode includes a second material that is a corrodible metallic material, and at least one heat source coupled to one of the first electrode and the second electrode and configured to apply a temperature gradient across the first end and the second end of the interlayer, and wherein the first electrode and the second electrode are configured to output a non-zero electrical voltage in response to the application of the temperature gradient. |
| FILED | Tuesday, December 14, 2021 |
| APPL NO | 17/550874 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/24 (20130101) H01L 35/30 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220190839 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhi Yang (Minneapolis, Minnesota); Anh Tuan Nguyen (Minneapolis, Minnesota); Diu Khue Luu (Minneapolis, Minnesota); Jian Xu (Minneapolis, Minnesota) |
| ABSTRACT | A digital-to-analog converter device including a set of components, each component included in the set of components including a number of unit cells, each unit cell being associated with a unit cell size indicating manufacturing specifications of the unit cell is provided by the present disclosure. The digital-to-analog converter device further includes a plurality of switches, each switch included in the plurality of switches being coupled to a component included in the set of components, and an output electrode coupled to the plurality of switches. The digital-to-analog converter device is configured to output an output signal at the output electrode. A first unit cell size associated with a first unit cell included in the set of components is different than a second unit cell size associated with a second unit cell included in the set of components. |
| FILED | Monday, March 07, 2022 |
| APPL NO | 17/687765 |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 1/007 (20130101) H03M 1/46 (20130101) Original (OR) Class H03M 1/447 (20130101) H03M 1/802 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20220183271 | Scharf et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MEMBRANE PROTECTIVE TECHNOLOGIES, INC. (Fort Collins, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Amy Scharf (Fort Collins, Colorado); Lisa A. Herickhoff (Fort Collins, Colorado); James Herickhoff (Fort Collins, Colorado); Myles Shepherd (Nunn, Colorado) |
| ABSTRACT | Embodiments of the present invention provide ways to reduce detrimental impacts to in vitro and in vivo specimens (8) from temperature depression with certain medium (9) and may include providing a protective layer (7) around a droplet (12) which may contain a medium and a specimen before subjecting to temperature depression. Other embodiments may provide treatment to a recipient environment (41) before implantation of a specimen (40) which has been subjected to a temperature depression. |
| FILED | Friday, March 13, 2020 |
| APPL NO | 17/438830 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0221 (20130101) Original (OR) Class A01N 1/0226 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220183287 | MEYER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | SUSAN L. MEYER (COLUMBIA, Maryland); AIJUN ZHANG (LAUREL, Maryland); MARGARET H. MACDONALD (LAUREL, Maryland); YAN FENG (BOWIE, Maryland) |
| ABSTRACT | The present disclosure provides methods for killing pests such as nematodes, oomycetes, and fungi, involving treating an object or area with an effective amount of a composition containing at least one compound of formula 1, wherein R1 is CH3, C2H5, C3H7; saturated or unsaturated, straight or branched, or halogen substituted alkyl; and wherein R2 are independently H, halogen, nitrogen, oxygen, sulfur, saturated or unsaturated, straight or branched alkyl, alkenyl, alkyl halide, aldehyde, ketone, ether, ester, amine, or amide; optionally methyl benzoate, optionally a surfactant, and optionally a carrier. |
| FILED | Thursday, December 09, 2021 |
| APPL NO | 17/546331 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/02 (20130101) A01N 33/18 (20130101) A01N 37/10 (20130101) Original (OR) Class A01N 37/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220183291 | MANOHAR et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH, INC. (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Murli MANOHAR (Ithaca, New York); Frank SCHROEDER (Ithaca, New York) |
| ABSTRACT | Compositions and methods for protecting an organism from a pathogen are disclosed. |
| FILED | Friday, April 17, 2020 |
| APPL NO | 17/603021 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 43/16 (20130101) Original (OR) Class Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220185848 | YU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | QINGZHONG YU (ATHENS, Georgia); STEPHEN J. SPATZ (BOGART, Georgia); JOHN R. DUNN (EAST LANSING, Georgia) |
| ABSTRACT | Provided herein are immunogenic compositions containing recombinant viruses capable of inducing protection in poultry against both Marek's disease virus (MDV) and Newcastle disease virus (NDV). Such viruses incorporate nucleic acids for expressing at least one MDV antigen, such as glycoprotein B, and antigenic portions thereof, in a recombinant NDV genome. |
| FILED | Monday, February 28, 2022 |
| APPL NO | 17/682358 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/055 (20130101) C07K 14/125 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220188343 | Uysal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ismail Uysal (Lakeland, Florida); Alla Abdella (West Hartford, Connecticut) |
| ABSTRACT | In accordance with some embodiments, systems, methods, and media for processing and representing multivariate sensor information gathered from multiple sources are provided. In some embodiments, the method comprises: receiving a data sequences from respective sources; identifying a shortest data sequence that corresponds to a first interval; calculating, for pairs of data sequences, a similarity value over the first interval; forming a first segment of a representative data sequence that is a weighted combination of the data sequences over the first interval based on similarity values associated with the data sequences; truncating at least a subset of data sequences to exclude elements corresponding to the first interval; identifying a shortest data sequence corresponding to a second interval; forming a second segment of the representative data sequence based on similarity values associated with the data sequences; and concatenating the first segment and the second segment of the representative data sequence. |
| FILED | Tuesday, December 14, 2021 |
| APPL NO | 17/550509 |
| CURRENT CPC | Electric Digital Data Processing G06F 16/353 (20190101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20220184113 | Chatterjee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anushree Chatterjee (Boulder, Colorado); Thomas R. Aunins (Boulder, Colorado); Prashant Nagpal (Lafayette, Colorado) |
| ABSTRACT | The inventive technology generally relates to systems, methods, and compositions for the treatment of viral infections, as well as novel use of antisense technology to rationally design antiviral compositions that can be applied to clinical cases and human infections. In one preferred aspect, the inventive technology includes methods, and compositions to treat COVID-19 in humans through the targeted inhibition of viral genome expression. |
| FILED | Thursday, December 09, 2021 |
| APPL NO | 17/546177 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) Original (OR) Class A61K 38/10 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1131 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220185675 | King et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WiSys Technology Foundation, Inc. (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Seth Thomas King (Holmen, Wisconsin); Daniel John Little (Onalaska, Wisconsin) |
| ABSTRACT | Various embodiments provide a zinc oxide graphene composite. A zinc oxide graphene composite includes zinc oxide crystallites and graphene. A method of forming the composite includes combining graphene and zinc oxalate to form a mixture and heating the mixture to produce the zinc oxide graphene composite. |
| FILED | Wednesday, April 01, 2020 |
| APPL NO | 17/594087 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/194 (20170801) Original (OR) Class C01B 2204/22 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/60 (20130101) C01P 2002/72 (20130101) C01P 2002/82 (20130101) C01P 2002/85 (20130101) C01P 2004/03 (20130101) C01P 2004/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220187533 | Leifer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Stephanie D. Leifer (Pasadena, California); Wei Zhang (Pasadena, California); Andrey B. Matsko (Arcadia, California) |
| ABSTRACT | Disclosed herein is a pulse repetition rate multiplier including a photonic integrated circuit (PIC) including cascading Mach-Zehnder interferometers (MZIs). An input may be connected to one end of the PIC and an output may be connected to the other end of the PIC such that a signal from the input runs through the cascading MZIs and out the output. The input may be configured to receive an input pulsed signal and the output may be configured to output a repetition rate multiplied signal. Advantageously, using a PIC as opposed to an optical fiber-based pulse rate multiplier allows for accurate fabrication of a pulse repetition rate multiplier configured to accept higher frequency pulsed signals. |
| FILED | Monday, December 13, 2021 |
| APPL NO | 17/643974 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/125 (20130101) G02B 6/12007 (20130101) Original (OR) Class G02B 2006/1215 (20130101) G02B 2006/12061 (20130101) G02B 2006/12147 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/212 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220190664 | MANDEL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (COLLEGE PARK, Maryland); UNIVERSITY OF WISCONSIN-MADISON (MADISON, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | RAPHAEL KAHAT MANDEL (WEST HARTFORD, Connecticut); F. PATRICK MCCLUSKEY (ELLICOTT CITY, Maryland); ZHAOXI YAO (COLLEGE PARK, Maryland); THOMAS JAHNS (MADISON, Wisconsin); BULENT SARLIOGLU (MADISON, Wisconsin); JAMES SWANKE (EDINA, Minnesota); DHEERAJ BOBBA (MADISON, Wisconsin) |
| ABSTRACT | The thermal management system for in-slot cooling of electric motors includes separating structures, either in the form of a scaffolding structure or a monolithic winding structure which is placed in between the adjacent winding turns to physically separate the winding turns to define coolant fluid passages for circulation of a coolant fluid in direct contact with the lateral surfaces of the winding turns. The scaffolding and monolithic winding structures are made from an electrically insulating material and are filled with a dielectric fluid that serves both the coolant and the electrical insulator between the winding turns. An end-winding organizer may be positioned at two end regions of each stator tooth to provide a curved surface for the winding turns to be held in tension throughout the 180° winding end turns and is formed with grooves to define the passage for the coolant flow to ensure that the flowing coolant reaches the surface of the innermost winding turns. |
| FILED | Thursday, December 16, 2021 |
| APPL NO | 17/644629 |
| CURRENT CPC | Dynamo-electric Machines H02K 3/24 (20130101) Original (OR) Class H02K 9/193 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 20220185350 | Kindt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Transportation Technology Center, Inc. (Pueblo, Colorado) |
| ASSIGNEE(S) | Transportation Technology Center, Inc. (Pueblo, Colorado) |
| INVENTOR(S) | Joel Donald Kindt (Colorado Springs, Colorado); Alan Lee Polivka (Pueblo West, Colorado); Paulo Roberto Vieira (Pueblo, Colorado) |
| ABSTRACT | A system of train control uses a quasi-moving block methodology for controlling operation of a plurality of trains from a remote office. The office parses the route information for each train into non-overlapping movement authorities that are issued via a communications network. As each train proceeds, it communicates with the office to automatically roll up its movement authority and release the portion of the movement authority behind the train. The office then extends the movement authority of the subsequent train to reflect the released portion of the movement authority of the leading train. The track can be divided into a series of track circuits to enable detection of broken rail or unexpected occupancy. The office segment can then control operation of trains accordingly if broken rail or unexpected occupancy is detected in the train's movement authority. |
| FILED | Wednesday, December 15, 2021 |
| APPL NO | 17/552218 |
| CURRENT CPC | Guiding Railway Traffic; Ensuring the Safety of Railway Traffic B61L 1/18 (20130101) B61L 23/34 (20130101) B61L 23/044 (20130101) B61L 25/021 (20130101) B61L 27/20 (20220101) Original (OR) Class B61L 27/70 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220187842 | Dai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | West Virginia University Board of Governors on Behalf of West Virginia University (Morgantown, West Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Fei Dai (Morgantown, West Virginia); Linjun Lu (Morgantown, West Virginia) |
| ABSTRACT | Disclosed is a thermal-based automatic roller tracking and mapping system for roller path tracking and mapping in pavement compaction. Accuracy in estimation during roller position tracking and mapping for pavement compaction through the use of thermal imaging is achieved. The tracking and mapping system utilizes an infrared camera for automatic roller path tracking and mapping in pavement construction. The tracking and mapping data associated with the movement of the roller vehicle during compaction of the surface can be generated and visually represented in a user interface accessible to the operator of the roller vehicle. Based on the tracking and mapping data that is generated in real-time and presented to the operator in the user interface, the operator can make adjustments to the roller vehicle and path, as necessary. |
| FILED | Monday, November 29, 2021 |
| APPL NO | 17/536418 |
| CURRENT CPC | Vehicles, Vehicle Fittings, or Vehicle Parts, Not Otherwise Provided for B60R 1/22 (20220101) B60R 11/04 (20130101) Construction Of, or Surfaces For, Roads, Sports Grounds, or the Like; Machines or Auxiliary Tools for Construction or Repair E01C 19/488 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0242 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 5/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20220183271 | Scharf et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MEMBRANE PROTECTIVE TECHNOLOGIES, INC. (Fort Collins, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Amy Scharf (Fort Collins, Colorado); Lisa A. Herickhoff (Fort Collins, Colorado); James Herickhoff (Fort Collins, Colorado); Myles Shepherd (Nunn, Colorado) |
| ABSTRACT | Embodiments of the present invention provide ways to reduce detrimental impacts to in vitro and in vivo specimens (8) from temperature depression with certain medium (9) and may include providing a protective layer (7) around a droplet (12) which may contain a medium and a specimen before subjecting to temperature depression. Other embodiments may provide treatment to a recipient environment (41) before implantation of a specimen (40) which has been subjected to a temperature depression. |
| FILED | Friday, March 13, 2020 |
| APPL NO | 17/438830 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0221 (20130101) Original (OR) Class A01N 1/0226 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220188671 | Jain et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vignet Incorporated (Fairfax, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Praduman Jain (Fairfax, Virginia); Dave Klein (Oakton, Virginia); Josh Schilling (Salem, Oregon) |
| ABSTRACT | Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for using machine learning to improve processes for achieving readiness. In some implementations, a database is accessed to obtain status data that indicates activities or attributes of a subject. One or more readiness scores indicating a level of capability of the subject to satisfy one or more readiness criteria are generated. Data is accessed indicating multiple candidate actions for improving capability of the subject to satisfy one or more readiness criteria. A subset of the candidate actions for the subject are selected based on the one or more readiness scores generated using the one or more models. Output is provided to cause one or more of the actions in the selected subset to be performed or cause an indication one or more of the actions in the selected subset to be presented on a user interface. |
| FILED | Friday, September 10, 2021 |
| APPL NO | 17/472232 |
| CURRENT CPC | Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 24/00 (20130101) Computer Systems Based on Specific Computational Models G06N 5/04 (20130101) Original (OR) Class G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 20220186111 | Zimmer |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Environmental Protection Agency (Washington, District of Columbia) |
| ASSIGNEE(S) | U.S. Environmental Protection Agency (Washington, District of Columbia) |
| INVENTOR(S) | Anthony Todd Zimmer (Cincinnati, Ohio) |
| ABSTRACT | A particle for emulating pollutant tracking in water has a florescent core. A semitransparent shell is formed around the florescent core. |
| FILED | Friday, December 11, 2020 |
| APPL NO | 17/118875 |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 11/025 (20130101) Original (OR) Class C09K 2211/1007 (20130101) C09K 2211/1018 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/06 (20130101) G01N 33/18 (20130101) G01N 2015/0693 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 20220188343 | Uysal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ismail Uysal (Lakeland, Florida); Alla Abdella (West Hartford, Connecticut) |
| ABSTRACT | In accordance with some embodiments, systems, methods, and media for processing and representing multivariate sensor information gathered from multiple sources are provided. In some embodiments, the method comprises: receiving a data sequences from respective sources; identifying a shortest data sequence that corresponds to a first interval; calculating, for pairs of data sequences, a similarity value over the first interval; forming a first segment of a representative data sequence that is a weighted combination of the data sequences over the first interval based on similarity values associated with the data sequences; truncating at least a subset of data sequences to exclude elements corresponding to the first interval; identifying a shortest data sequence corresponding to a second interval; forming a second segment of the representative data sequence based on similarity values associated with the data sequences; and concatenating the first segment and the second segment of the representative data sequence. |
| FILED | Tuesday, December 14, 2021 |
| APPL NO | 17/550509 |
| CURRENT CPC | Electric Digital Data Processing G06F 16/353 (20190101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, June 16, 2022.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-applications-20220616.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page