FedInvent™ Patent Applications
Application Details for Thursday, July 21, 2022
This page was updated on Monday, July 25, 2022 at 12:00 PM GMT
Department of Health and Human Services (HHS)
| US 20220225882 | ROGERS et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John A. ROGERS (Evanston, Illinois); Li GAO (Urbana, Illinois); Viktor MALYARCHUK (Urbana, Illinois); Richard Chad WEBB (Urbana, Illinois) |
| ABSTRACT | Provided are tissue-mounted devices and methods for monitoring a thermal transport property (e.g., thermal conductivity, thermal diffusivity, heat capacity) of tissue, such as skin. The devices conformally mount to the tissue and have one or more thermal actuators and a plurality of sensors. The actuator applies heat to the tissue and the sensors to detect a spatio temporal distribution of a physiological tissue parameter or physical property resulting from the heating. This spatio temporal information may be correlated with a rate, velocity and/or direction of blood flow, the presence of a vascular occlusion, circulation changes due to inflammation, hydration level and other physiological parameters. |
| FILED | Thursday, September 30, 2021 |
| APPL NO | 17/491316 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/002 (20130101) A61B 5/015 (20130101) Original (OR) Class A61B 5/028 (20130101) A61B 5/0048 (20130101) A61B 5/0205 (20130101) A61B 5/0261 (20130101) A61B 5/318 (20210101) A61B 5/369 (20210101) A61B 5/389 (20210101) A61B 5/0537 (20130101) A61B 5/683 (20130101) A61B 5/02007 (20130101) A61B 5/4875 (20130101) A61B 5/6802 (20130101) A61B 5/6824 (20130101) A61B 5/6832 (20130101) A61B 2560/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220225910 | Plaxco et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Kevin Plaxco (Santa Barbara, California); Netzahualcoyotl Arroyo Curras (Baltimore, Maryland); Andrea Idili (Rome, Italy) |
| ABSTRACT | Improved electrochemical sensors wherein the recognition element is co-deposited with a secondary, charge transfer modulating moiety, for example an oligonucleotide. The secondary moiety modulates electron transfer kinetics to enhance the frequency dependence of sensor gain, enabling the use of kinetic differential drift correction techniques and like measurements that require a target insensitive signal drifts in parallel with target-dependent output. The secondary moiety also increases the gain and signal to noise of the sensor and can be used to enable calibration-free measurement. Accurate drift-corrected in vivo sensor use with multiple measurements of analyte concentration per minute in flowing blood is demonstrated. |
| FILED | Friday, June 12, 2020 |
| APPL NO | 17/617100 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1495 (20130101) A61B 5/14735 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226238 | PUDER et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Mark PUDER (Medfield, Massachusetts); Kathleen Marie GURA (Norfolk, Massachusetts) |
| ABSTRACT | Described herein are emulsion compositions comprising fish oil and medium-chain triglycerides (MCT) and/or omega-3 fatty acids and medium-chain triglycerides (MCT). In some embodiments, the compositions further comprise, e.g., alpha-tocopherol, or one or more fatty acids. Further provided herein are methods of using the compositions, e.g., to provide nutrion, e.g., parenteral nutrition to a subject and/or to treat or prevent certain conditions described herein. |
| FILED | Thursday, April 07, 2022 |
| APPL NO | 17/715612 |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/11 (20160801) A23L 33/15 (20160801) A23L 33/40 (20160801) A23L 33/115 (20160801) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/107 (20130101) Original (OR) Class A61K 31/23 (20130101) A61K 31/202 (20130101) A61K 31/355 (20130101) A61K 35/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226265 | Nystoriak et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (Louisville, Kentucky) |
| ASSIGNEE(S) | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (Louisville, Kentucky) |
| INVENTOR(S) | Matthew Nystoriak (Floyds Knobs, Indiana); Aruni Bhatnagar (Prospect, Kentucky) |
| ABSTRACT | In certain embodiments, the present invention provides a method of modulating myocardial blood flow (MBF) as compared to a control in a patient in need thereof, comprising administering an agent that interacts with a Kvβ protein. |
| FILED | Tuesday, January 18, 2022 |
| APPL NO | 17/577821 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/137 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/08 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226266 | Kellum et al. |
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| APPLICANT(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
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| INVENTOR(S) | John A. Kellum (Pittsburgh, Pennsylvania); Neil Hukriede (Allison Park, Pennsylvania); Xiaoyan Wen (Pittsburgh, Pennsylvania) |
| ABSTRACT | Provided herein is a method of treating kidney injury associated with trauma or infection, such as in sepsis-associated acute kidney injury. |
| FILED | Monday, June 01, 2020 |
| APPL NO | 17/614191 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/167 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 13/12 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226270 | Bazan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana); University of Southern California (Los Angeles, Louisiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicolas G. Bazan (New Orleans, Louisiana); Haydee E.P. Bazan (New Orleans, Louisiana); Nicos A. Petasis (Los Angeles, California) |
| ABSTRACT | Provided are methods of using compounds, pharmaceutical compositions, cosmetic and dermatological compositions or nutritional supplement compositions, comprising omega-3 very-long-chain polyunsaturated fatty acids (n-3 VLC-PUFAs) and/or their endogenous hydroxylated derivatives thereof, known as elovanoids for promoting the protection, prevention, and treatment of disturbances of the eye surface, such as dry eye and inflammatory conditions of the eye surface. |
| FILED | Monday, April 06, 2020 |
| APPL NO | 17/601289 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/167 (20130101) A61K 31/202 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) A61P 27/02 (20180101) A61P 29/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226284 | Baker et al. |
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| APPLICANT(S) | University of South Florida (Tampa, Florida) |
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| INVENTOR(S) | Bill J. Baker (Temple Terrace, Florida); Kyle Rohde (Orlando, Florida); Bingjie Yang (Temple Terrace, Florida); Marisa Fuse (Winter Springs, Florida) |
| ABSTRACT | The present disclosure provides methods for the treatment of infections with Mycobacterium such as tuberculosis or leprosy. |
| FILED | Tuesday, April 05, 2022 |
| APPL NO | 17/713576 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/12 (20130101) A61K 31/44 (20130101) A61K 31/133 (20130101) A61K 31/145 (20130101) A61K 31/192 (20130101) A61K 31/235 (20130101) A61K 31/343 (20130101) A61K 31/352 (20130101) A61K 31/365 (20130101) A61K 31/366 (20130101) Original (OR) Class A61K 31/454 (20130101) A61K 31/472 (20130101) A61K 31/496 (20130101) A61K 31/498 (20130101) A61K 31/505 (20130101) A61K 31/4015 (20130101) A61K 31/4045 (20130101) A61K 31/4409 (20130101) A61K 31/7036 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226289 | Taylor |
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| FUNDED BY |
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| APPLICANT(S) | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (Memphis, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph Paul Taylor (Memphis, Tennessee) |
| ABSTRACT | Methods and formulations are provided for treating spinobulbar muscular atrophy in a subject in need thereof. By administering a therapeutically effective amount of a selective androgen receptor modulator or a small molecule such as 1-[2-(4-methylphenoxy)ethyl]-2-[(2-phenoxyethyl)sulfanyl]-1H-benzimidazole or a derivative, prodrug, or pharmaceutically acceptable salt thereof, one or more symptoms of spinobulbar muscular atrophy can be ameliorated. The effective amount can be effective to prevent or delay loss of body weight, a loss of mobility, and/or a loss of physical strength in the subject; to prevent or delay neurogenic atrophy and/or to prevent a loss of spinal cord motor neurons in the subject; to restore the frequency of type I myofibers to normal levels for a healthy subject; and/or to reverse testicular atrophy in the subject. |
| FILED | Friday, October 26, 2018 |
| APPL NO | 16/759715 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4184 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226311 | HERGENROTHER et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Paul J. HERGENROTHER (Champaign, Illinois); Timothy M. FAN (Mahomet, Illinois); Matthew BOUDREAU (Urbana, Illinois); William MONTGOMERY (Dallas, Texas); Hyang-Yeon LEE (Savoy, Illinois); Marlies HAGER (Lincoln, Nebraska); Diana RANOA (Champaign, Illinois); Myung-ryul LEE (Savoy, Illinois) |
| ABSTRACT | The blood-brain barrier penetrant procaspase-3-activating drug, PAC-1, has been identified as an effective approach to inducing immune stimulatory destruction of cancer cells. PAC-1 induces cleavage of MLH1 in cancer cells, and studies show that inactivation of MLH1 leads to increased mutational burden and neoantigen presentation by major histocompatibility complex (MHC) products. Herein is described a mechanistic-based strategy to bring the power of immunotherapy in an effective fashion for treatment of cancer. |
| FILED | Monday, June 01, 2020 |
| APPL NO | 17/615402 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/08 (20130101) A61K 9/0014 (20130101) A61K 9/0019 (20130101) A61K 9/0078 (20130101) A61K 9/485 (20130101) A61K 9/2013 (20130101) A61K 9/2018 (20130101) A61K 9/2027 (20130101) A61K 9/2054 (20130101) A61K 9/2059 (20130101) A61K 9/4858 (20130101) A61K 9/4866 (20130101) A61K 31/495 (20130101) Original (OR) Class A61K 39/0011 (20130101) A61K 39/3955 (20130101) A61K 47/02 (20130101) A61K 47/10 (20130101) A61K 47/12 (20130101) A61K 47/14 (20130101) A61K 47/26 (20130101) A61K 47/38 (20130101) A61K 47/44 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226320 | Li |
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| APPLICANT(S) | Marshall University Research Corporation (Huntington, West Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Wei Li (Huntington, West Virginia) |
| ABSTRACT | Methods for treating obesity, atherosclerosis, and/or thrombosis comprise reducing an expression level or activity of thymidine phosphorylase in a subject in need thereof. Reducing the expression level or activity of thymidine phosphorylase as part of a method for treatment of obesity, atherosclerosis, and/or thrombosis can comprise administering to the subject an effective amount of a thymidine phosphorylase inhibitor. The thymidine phosphorylase inhibitor administered to the subject can be tipiracil, which can be administered alone or in combination with other therapeutic agents, including tissue plasminogen activator and aspirin. |
| FILED | Thursday, May 14, 2020 |
| APPL NO | 17/610909 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/04 (20180101) A61P 3/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226321 | PRICE et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Theodore J. PRICE (Dallas, Texas); Stephanie I. SHIERS (Plano, Texas) |
| ABSTRACT | The disclosure provides methods and compositions for inhibiting pain and comorbid cognitive deficits by administering a MNK inhibitor to a subject in need thereof. Also provided are methods of using the inhibitor in combination with other pain therapies. |
| FILED | Friday, May 22, 2020 |
| APPL NO | 17/613292 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226329 | Kawai |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
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| INVENTOR(S) | Tatsuo Kawai (Weston, Massachusetts) |
| ABSTRACT | Provided herein are methods for inducing chimerism in a patient. Specifically, provided herein are improved methods for inducing a state in the recipient of allogeneic hematopoietic stem cells such that the lymphohematopoietic system of the recipient comprises a mixture of host and donor cells. Compositions, kits, and systems for use with these methods are also disclosed. |
| FILED | Friday, May 08, 2020 |
| APPL NO | 17/609181 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) Original (OR) Class A61K 31/635 (20130101) A61K 35/28 (20130101) A61K 38/13 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226347 | SLAGA et al. |
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| APPLICANT(S) | Board of Regents, the University of Texas System (, None) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thomas J. SLAGA (San Antonio, Texas); Jacob JUNCO (San Antonio, Texas); Huiyun LIANG (San Antonio, Texas); Sara REYNA (San Antonio, Texas) |
| ABSTRACT | Certain embodiments are directed to methods and compositions for treating obesity, diabetes, and/or cancer with a combination of ursolic acid and resveratrol. |
| FILED | Saturday, April 17, 2021 |
| APPL NO | 17/233456 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/05 (20130101) A61K 31/19 (20130101) A61K 31/56 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/04 (20180101) A61P 3/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226361 | Freier |
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| FUNDED BY |
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| APPLICANT(S) | Ionis Pharmaceuticals, Inc. (Carlsbad, California) |
| ASSIGNEE(S) | Ionis Pharmaceuticals, Inc. (Carlsbad, California) |
| INVENTOR(S) | Susan M. Freier (San Diego, California) |
| ABSTRACT | Disclosed herein are compounds and methods for decreasing MECP2 mRNA and protein expression. Such compounds and methods are useful to treat, prevent, or ameliorate MECP2 associated disorders and syndromes. Such MECP2 associated disorders include MECP2 duplication syndrome. |
| FILED | Monday, August 23, 2021 |
| APPL NO | 17/408920 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/712 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/22 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226362 | LU et al. |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
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| INVENTOR(S) | Zheng-Rong LU (Cleveland, Ohio); Anthony MALAMAS (Cleveland, Ohio); Maneesh GUJRATI (Cleveland, Ohio); Da SUN (Cleveland, Ohio) |
| ABSTRACT | A compound comprising formula (I): wherein R1 is an akylamino group or a group containing at least one aromatic group; R2 and R3 are independently an aliphatic group or hydrophobic group; R4 and R5 are independently H, a substituted or unsubstituted akyl group, an akenyl group, an acyl group, an aromatic group, polymer, a targeting group, or a detectable moiety; a, b, c, and d are independently an integer from 1 to 10; and pharmaceutically acceptable salts thereof. |
| FILED | Tuesday, September 28, 2021 |
| APPL NO | 17/487562 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Original (OR) Class A61K 48/0033 (20130101) Peptides C07K 5/0606 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2320/31 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226363 | Pyle et al. |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
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| INVENTOR(S) | Anna Marie Pyle (Guilford, Connecticut); Akiko Iwasaki (Guilford, Connecticut); Tianyang Mao (New Haven, Connecticut) |
| ABSTRACT | The present disclosure provides small hairpin nucleic acid molecules capable of stimulating interferon production. The nucleic acid molecules of the present disclosure has a double-stranded section of less than 19 base pairs and at least one blunt end. In certain embodiments, the molecule comprises at least one 5′-triphosphate and/or at least one 5′-diphosphate. In certain embodiments, compounds and/or compositions of the disclosure are useful for treating, ameliorating, and/or preventing SARS-CoV-2 viral infection, and/or ameliorating, minimizing, reversing, and/or preventing persistent SARS-CoV-2 viral infection, and/or minimizing or preventing SARS-CoV-2 viral infection-derived mortality and/or lethality, in a subject. In certain embodiments, compounds and/or compositions of the disclosure are useful for treating, ameliorating, and/or preventing SARS-CoV-2 viral infection in a tumor-bearing subject. In certain embodiments, compounds and/or compositions of the disclosure are useful for treating, ameliorating, and/or preventing SARS-CoV-2 viral infection in an immune-compromised and/or immunodeficient subject. |
| FILED | Wednesday, March 30, 2022 |
| APPL NO | 17/709275 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226364 | Jones et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Peter L. Jones (Carson City, Nevada); Michael R. Green (Boylston, Massachusetts) |
| ABSTRACT | The disclosure relates to methods and compositions for regulating expression of DUX4. In some aspects, methods described by the disclosure are useful for treating a disease associated with aberrant DUX4 expression (e.g., facioscapulohumeral muscular dystrophy). |
| FILED | Wednesday, April 06, 2022 |
| APPL NO | 17/714349 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 31/7105 (20130101) Original (OR) Class A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/90 (20130101) C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/20 (20170501) C12N 2740/16043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226379 | GOTTSCHALK et al. |
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| FUNDED BY |
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| APPLICANT(S) | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (Memphis, Tennessee) |
| ASSIGNEE(S) | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (Memphis, Tennessee) |
| INVENTOR(S) | Stephen GOTTSCHALK (Germantown, Tennessee); Giedre KRENCIUTE (Memphis, Tennessee); Christopher PETERSEN (Memphis, Tennessee); Benjamin YOUNGBLOOD (Memphis, Tennessee) |
| ABSTRACT | The application provides modified immune effector cells wherein the DNA (cytosine-5)-methyltransferase 3A (DNMT3A)-mediated de novo DNA methylation of the cell genome is inhibited, and STAT5 signaling pathway is activated. The application also provides related pharmaceutical compositions and the methods for generating such modified immune effector cells. The application further provides uses of such modified immune effector cells for treating diseases such as cancers, infectious diseases and autoimmune diseases. |
| FILED | Wednesday, April 08, 2020 |
| APPL NO | 17/602524 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 35/545 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1007 (20130101) C12N 2510/00 (20130101) Enzymes C12Y 201/01037 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226430 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Texas A and M University System (College Station, Texas); University of Maryland, Baltimore (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhilei Chen (College Station, Texas); Rudo Simeon (Bryan, Texas); Ana M. Chamoun-Emanuelli (College Station, Texas); Zeyu Peng (Kunming, China PRC); Hanping Feng (Baltimore, Maryland); Hua Yu (Columbia, Maryland); Yongrong Zhang (Columbia, Maryland) |
| ABSTRACT | In an embodiment, the present disclosure pertains to a method of treating or preventing C. difficile infections. In some embodiments, the method includes administering an antitoxin to a subject in need thereof. In some embodiments, the antitoxin includes a designed ankyrin repeat protein (DARPin). In an additional embodiments, the present disclosure pertains to a composition including an antitoxin for treating or preventing C. difficile infections. In some embodiments, the anti-toxin includes a DARPin. In some embodiments, the anti-toxin is a monomeric or dimeric DARPin for the neutralization of Clostridium difficile toxin B (TcdB). |
| FILED | Monday, May 11, 2020 |
| APPL NO | 17/609818 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/164 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 39/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226437 | Stankovic et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Konstantina Stankovic (Boston, Massachusetts); Nadia A. Atai (Boston, Massachusetts); Brad Welling (Boston, Massachusetts); Richard Seist (Cambridge, Massachusetts) |
| ABSTRACT | Methods of using Fibroblast growth factor 2 (FGF2) to treat subjects with hearing loss associated with impaired word recognition. |
| FILED | Friday, May 29, 2020 |
| APPL NO | 17/614845 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0046 (20130101) A61K 38/1825 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/16 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226458 | Collins et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as Represented by the Secretary, Department of (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary, Department of (Bethesda, Maryland) |
| INVENTOR(S) | Peter L. Collins (Silver Spring, Maryland); Ursula J. Buchholz (Silver Spring, Maryland); Bo Liang (Bethesda, Maryland); Shirin Munir (Bethesda, Maryland) |
| ABSTRACT | Recombinant chimeric bovine/human parainfluenza virus 3 (rB/HPIV3) vectors expressing Respiratory Syncytial Virus (RSV) G protein or a recombinant RSV G protein, as well as methods of their use and manufacture, are provided. The rB/HPIV3 vector comprises a genome comprising a heterologous gene encoding the RSV G protein or the recombinant RSV G protein. Nucleic acid molecules comprising the sequence of the genome or antigenome of the disclosed rB/HPIV3 vectors are also provided. The disclosed rB/HPIV3 vectors can be used, for example, to induce an immune response to RSV and HPIV3 in a subject. |
| FILED | Tuesday, February 01, 2022 |
| APPL NO | 17/590631 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/5254 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226461 | Weissman et al. |
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| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Drew Weissman (Wynnewood, Pennsylvania); Norbert Pardi (Philadelphia, Pennsylvania) |
| ABSTRACT | The present invention relates to compositions and methods for inducing an adaptive immune response in a subject. In certain embodiments, the present invention provides a composition comprising a nucleoside-modified nucleic acid molecule encoding an antigen, adjuvant, or a combination thereof. For example, in certain embodiments, the composition comprises a vaccine comprising a nucleoside-modified nucleic acid molecule encoding an antigen, adjuvant, or a combination thereof. |
| FILED | Monday, March 28, 2022 |
| APPL NO | 17/705837 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/127 (20130101) A61K 31/712 (20130101) A61K 31/7115 (20130101) A61K 39/002 (20130101) A61K 39/02 (20130101) A61K 39/0011 (20130101) A61K 39/12 (20130101) Original (OR) Class A61K 2039/51 (20130101) A61K 2039/55555 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/16 (20180101) A61P 31/18 (20180101) A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 219/08 (20130101) Heterocyclic Compounds C07D 295/13 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226464 | Kazer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Samuel Kazer (Cambridge, Massachusetts); Alexander K. Shalek (Cambridge, Massachusetts) |
| ABSTRACT | A method of modulating immune response to an infection in a subject, the method comprising contacting CD4+ T cells, monocytes, cytotoxic lymphocytes (CTLs), natural killer (NK) cells, and/or proliferating T cells in the subject with one or more modulating agents, wherein the one or more modulating agents modulate genes in one or more of pathways and cell populations. |
| FILED | Thursday, May 28, 2020 |
| APPL NO | 17/614602 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) A61K 38/465 (20130101) A61K 39/21 (20130101) Original (OR) Class A61K 39/39 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) A61P 37/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226481 | Gray et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts); BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts); BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Nathanael Gray (Boston, Massachusetts); Inchul You (Boston, Massachusetts); Tinghu Zhang (Brookline, Massachusetts); Eric Fischer (Chestnut Hill, Massachusetts); Katherine Donovan (Boston, Massachusetts); Emily Erickson (Brookline, Massachusetts); Alex Toker (Dedham, Massachusetts) |
| ABSTRACT | Disclosed are bifunctional compounds comprising a GDC-0068 analog that binds AKT isoforms AKT1, 2 and 3, pharmaceutical compositions, and methods for treating diseases or conditions mediated by dysfunctional AKT activity. |
| FILED | Wednesday, April 08, 2020 |
| APPL NO | 17/601640 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 47/55 (20170801) Original (OR) Class A61K 47/545 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226487 | Brown et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SRI INTERNATIONAL (Menlo Park, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kathlynn C. Brown (Staunton, Virginia); Curtis Allred (Menlo Park, California); Michael McGuire (Harrisonburg, Virginia) |
| ABSTRACT | Disclosed herein, are compositions comprising one or more molecular guidance system (MGS) peptides and a cytotoxic agent. Also described herein, are methods of administering the compositions to patients with cancer. |
| FILED | Tuesday, July 10, 2018 |
| APPL NO | 16/629803 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/168 (20130101) A61K 45/06 (20130101) A61K 47/60 (20170801) A61K 47/6415 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226495 | YANG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sanofi (Paris, France) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhi-Yong YANG (Bridgewater, New Jersey); Gary J. NABEL (Bridgewater, New Jersey); Ling XU (Bridgewater, New Jersey); Jochen BENINGA (Frankfurt am Main, Germany); Jochen KRUIP (Erzhausen, Germany); Ercole RAO (Morfelden-Walldorf, Germany); Wulf Dirk LEUSCHNER (Frankfurt am Main, Germany); Christian BEIL (Frankfurt am Main, Germany); Christian LANGE (Frankfurt Am Main, Germany) |
| ABSTRACT | Provided herein are bivalent, bispecific binding proteins that specifically bind to two different HIV-1 Env protein epitopes. |
| FILED | Tuesday, August 17, 2021 |
| APPL NO | 17/404908 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 47/6881 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) Peptides C07K 16/468 (20130101) C07K 16/1063 (20130101) C07K 2317/31 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226508 | BARABAN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Scott C. BARABAN (Novato, California); Aliesha L. GRIFFIN (San Francisco, California); Adam R. RENSLO (Oakland, California); Priyadarshini JAISHANKAR (San Francisco, California) |
| ABSTRACT | Provided, inter alia, are methods and compositions for treating epilepsy. In one aspect, provided herein is a method of selecting a compound for treating epilepsy, said method includes, contacting a test compound with 5-hydroxytryptamine-2B receptor (5-HT2B), and measuring the 5-HT2B agonistic activity of the test compound. In another aspect, provided herein is a method of treating an epilepsy in a subject in need thereof. The method includes administering to said subject an effective amount of a 5-HT2B specific receptor agonist. |
| FILED | Thursday, May 28, 2020 |
| APPL NO | 17/595823 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0008 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226510 | Xu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xiaoding Xu (Boston, Massachusetts); Jinjun Shi (Boston, Massachusetts); Omid C. Farokhzad (Boston, Massachusetts) |
| ABSTRACT | Stimuli-responsive NPs with excellent stability, high loading efficiency, encapsulation of multiple agents, targeting to certain cells, tissues or organs of the body, can be used as delivery tools. These NPs contain a hydrophobic inner core and hydrophilic outer shell, which endows them with high stability and the ability to load therapeutic agents with high encapsulation efficiency. The NPs are preferably formed from amphiphilic stimulus-responsive polymers or a mixture of amphiphilic and hydrophobic polymers or compounds, at least one type of which is stimuli-responsive. These NPs can be made so that their cargo is released primarily within target certain cells, tissues or organs of the body, upon exposure to endogenous or exogenous stimuli. The rate of release can be controlled so that it may be a burst, sustained, delayed, or a combination thereof. The NPs have utility as research tools or for clinical applications including diagnostics, therapeutics, or combination of both. |
| FILED | Wednesday, January 26, 2022 |
| APPL NO | 17/585118 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1273 (20130101) A61K 9/5138 (20130101) A61K 9/5146 (20130101) A61K 9/5153 (20130101) A61K 47/65 (20170801) A61K 49/0021 (20130101) A61K 49/0032 (20130101) A61K 49/0054 (20130101) Original (OR) Class Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/286 (20200201) C08F 293/005 (20130101) C08F 2438/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226511 | GAO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Regents of The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Jinming GAO (Dallas, Texas); Baran SUMER (Dallas, Texas); Tian ZHAO (Dallas, Texas); Zachary T. BENNETT (Dallas, Texas) |
| ABSTRACT | Described herein are pH responsive compounds, micelles, and compositions useful for the detection of primary and metastatic tumor tissues. Compounds described herein are imaging agents useful for the detection of primary and metastatic tumor tissue (including lymph nodes). Real-time fluorescence imaging during surgery aids surgeon in the detection of metastatic lymph nodes or delineate tumor tissue versus normal tissue, with the goal of achieving negative margins and complete tumor resection. |
| FILED | Thursday, May 28, 2020 |
| APPL NO | 17/614638 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) A61K 49/0034 (20130101) A61K 49/0054 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 81/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226537 | Xie et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jingwei Xie (Omaha, Nebraska); Shixuan Chen (Omaha, Nebraska); Mark Carlson (Omaha, Nebraska) |
| ABSTRACT | Coated and expanded, nanofiber structures are provided and methods of use thereof. |
| FILED | Monday, April 04, 2022 |
| APPL NO | 17/712601 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/7007 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 24/0015 (20130101) A61L 24/0031 (20130101) A61L 24/046 (20130101) Original (OR) Class A61L 24/104 (20130101) A61L 27/18 (20130101) A61L 27/34 (20130101) A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 27/222 (20130101) A61L 2400/04 (20130101) A61L 2400/12 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0007 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 11/01 (20130101) Wall, Floor, or Like Covering Materials, e.g Linoleum, Oilcloth, Artificial Leather, Roofing Felt, Consisting of a Fibrous Web Coated With a Layer of Macromolecular Material; Flexible Sheet Material Not Otherwise Provided for D06N 3/0004 (20130101) D06N 2203/026 (20130101) D06N 2203/041 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226542 | Breuer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher Breuer (New Haven, Connecticut); Themis Kyriakides (New Haven, Connecticut); Jason Roh (New Haven, Connecticut) |
| ABSTRACT | Methods for increasing the patency of biodegradable, synthetic vascular grafts are provided. The methods include administering one or more cytokines and/or chemokines that promote outward tissue remodeling of the vascular grafts and vascular neotissue formation. The disclosed methods do not require cell seeding of the vascular grafts, thus avoiding many problems associated with cell seeding. Biodegradable, polymeric vascular grafts which provide controlled release of cytokines and/or chemokines at the site of vascular graft implantation are also provided. |
| FILED | Tuesday, April 05, 2022 |
| APPL NO | 17/713766 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/195 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/54 (20130101) A61L 27/507 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226543 | Yaszemski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota); The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael J. Yaszemski (Rochester, Minnesota); Anthony J. Windebank (Zumbro Falls, Minnesota); Ahad M. Siddiqui (Rochester, Minnesota); James L. Herrick (Rochester, Minnesota); Suzanne L. Glass (Winston Salem, North Carolina); Alan L. Miller, II (Rochester, Minnesota); Brian E. Waletzki (Eyota, Minnesota); Nicolas N. Madigan (Rochester, Minnesota); Jeffrey Schwartz (Princeton, New Jersey); Jean E. Schwarzbauer (Princeton, New Jersey); Kelly S. Lim (Princeton, New Jersey); Stephen B. Bandini (Princeton, New Jersey); Gregory M. Harris (Princeton, New Jersey); Jeffrey W. Chen (Princeton, New Jersey) |
| ABSTRACT | A matrix for neuron regeneration. The matrix can include a sheet having a first surface and a second surface opposite the first surface, the second surface having a plurality of integrally formed ridges. The sheet can have a spiral shape, such that the first surface of the sheet faces the second surface of the sheet. The sheet and the integrally formed ridges can comprise oligo(poly(ethylene glycol) fumarate). |
| FILED | Thursday, April 30, 2020 |
| APPL NO | 17/607245 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) A61K 35/30 (20130101) A61K 38/185 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/06 (20130101) A61L 27/16 (20130101) A61L 27/28 (20130101) A61L 27/047 (20130101) A61L 27/52 (20130101) Original (OR) Class A61L 27/383 (20130101) A61L 27/3834 (20130101) A61L 2430/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226651 | Efimov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The George Washington University (Washington, District of Columbia); Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Igor R. Efimov (Arlington, Virginia); Jaclyn Ann Brennan (Fairfax, Virginia); John A. Rogers (Evanston, Illinois) |
| ABSTRACT | Systems and methods are disclosed for an electrical sensing, pacing, and ablation device comprising a bendable and stretchable balloon catheter and a bendable and stretchable first layer connected to or embedded in said balloon catheter, where the first layer has an electrode array with a plurality of electrodes. The is also a bendable and stretchable second layer connected to or embedded in the balloon catheter, and the second layer has a pressure sensor array with a plurality of pressure sensors. |
| FILED | Wednesday, January 19, 2022 |
| APPL NO | 17/579218 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/1492 (20130101) A61B 2018/0022 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/1002 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/3627 (20130101) Original (OR) Class A61N 1/3684 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226674 | BURDETTE |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Acoustic MedSystems, Inc. (Savoy, Illinois) |
| ASSIGNEE(S) | Acoustic MedSystems, Inc. (Savoy, Illinois) |
| INVENTOR(S) | Everette C. BURDETTE (Savoy, Illinois) |
| ABSTRACT | A multi-angular ultrasound device. Multi-angular ablation patterns are achieved by a catheter-based ultrasound transducer having a plurality of transducer zones. A multi-chambered balloon is positioned on the catheter. |
| FILED | Monday, October 18, 2021 |
| APPL NO | 17/504301 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/12 (20130101) A61B 8/085 (20130101) A61B 8/445 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/022 (20130101) Original (OR) Class A61N 2007/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226815 | BROUZES et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| ASSIGNEE(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| INVENTOR(S) | Eric BROUZES (Port Jefferson, New York); Jin Zhu YU (Flushing, New York); Anu Priya Bharathi RAJAN (Stony Brook, New York); Jingfang JU (East Setauket, New York); Gabor BALAZSI (East Setauket, New York) |
| ABSTRACT | The present disclosure is directed to a microwell array comprising a plurality of wells of micro-size dimensions created on porous materials. The device can be used in various cell and tissue analytical activities, and can be formed using an etching, laminating or imprinting processes. |
| FILED | Friday, May 08, 2020 |
| APPL NO | 17/609485 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50851 (20130101) Original (OR) Class B01L 2200/12 (20130101) B01L 2300/021 (20130101) B01L 2300/161 (20130101) B01L 2300/0681 (20130101) B01L 2300/0829 (20130101) B01L 2400/049 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226830 | Chang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hsueh-Chia Chang (South Bend, Indiana); Liao Chen (South Bend, Indiana); Chenguang Zhang (South Bend, Indiana); FNU Vivek (South Bend, Indiana) |
| ABSTRACT | Described herein are methods and compositions for point of care droplet digital PCR (ddPCR) using large uniform droplets that can be visually analyzed for detection. In one embodiment, the ddPCR reaction is prepared by dispensing a plurality of large uniform droplets using a modified pipette tip having a specific aspect ratio and one or more surfactants in the aqueous phase. |
| FILED | Tuesday, January 18, 2022 |
| APPL NO | 17/577550 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 9/543 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227003 | Mahoor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dream Face Technologies, LLC (Lone Tree, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mohammad H. Mahoor (Centennial, Colorado); Joshua T. Lane (Englewood, Colorado); Hojjat Abdollahi Pourhaghighi (Denver, Colorado); Eshrat S. Emamian (Lone Tree, Colorado) |
| ABSTRACT | A companion robot is disclosed. In some embodiments, the companion robot may include a head having a facemask and a projector configured to project facial images onto the facemask; a facial camera; a microphone configured to receive audio signals from the environment; a speaker configured to output audio signals; and a processor electrically coupled with the projector, the facial camera, the microphone, and the speaker. In some embodiments, the processor may be configured to receive facial images from the facial camera; receive speech input from the microphone; determine an audio output based on the facial images and/or the speech input; determine a facial projection output based the facial images and/or the speech input; output the audio output via the speaker; and project the facial projection output on the facemask via the projector. |
| FILED | Friday, January 14, 2022 |
| APPL NO | 17/575640 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1697 (20130101) B25J 11/001 (20130101) B25J 11/0015 (20130101) Original (OR) Class B25J 13/003 (20130101) Electric Digital Data Processing G06F 3/0481 (20130101) Image or Video Recognition or Understanding G06V 40/174 (20220101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 25/63 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227714 | Alimardanov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNITED STATES OF AMERICA,AS REPRESENTED BY THE SECRETARY,DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Asaf Ragim Alimardanov (North Potomac, Maryland); Junfeng Huang (Woodstock, Maryland) |
| ABSTRACT | A process for the preparation of racemic and optically active (1E,NE)-N-(1-aminoethylidene)-3-(4-chlorophenyl)-4-phenyl-N′-((4-(trifluoromethyl)phenyl)sulfonyl)-4,5-dihydro-1H-pyrazole-1-carboximidamide in high enantiomerical purity is provided. |
| FILED | Thursday, April 30, 2020 |
| APPL NO | 17/610537 |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/07 (20130101) Heterocyclic Compounds C07D 231/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227724 | RADIC et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California); Oak Ridge National Laboratory (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zoran RADIC (San Diego, California); Carlo BALLATORE (La Jolla, California); Lukas GORECKI (Hradec Kralovy, Czech Republic); Palmer TAYLOR (La Jolla, California); Andrey KOVALEVSKY (Oak Ridge, Tennessee); Xiaolin CHENG (Oak Ridge, Tennessee) |
| ABSTRACT | In alternative embodiments, provided are uncharged bis-oxime antidotes that cross the blood-brain barrier (BBB) to catalyze the hydrolysis of organophosphate (OP)-inhibited human acetylcholinesterase (hAChE) in the central nerve system (CNS). In alternative embodiments, provided are pumps, devices, subcutaneous infusion devices, continuous subcutaneous infusion devices, infusion pens, needles, reservoirs, ampoules, a vial, a syringe, a cartridge, a disposable pen or jet injector, a prefilled pen or a syringe or a cartridge, a cartridge or a disposable pen or jet injector, a two chambered or multi-chambered pump, a syringe, a cartridge or a pen or a jet injector, comprising a compound as provided herein. |
| FILED | Thursday, May 21, 2020 |
| APPL NO | 17/613775 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 39/02 (20180101) Heterocyclic Compounds C07D 211/56 (20130101) C07D 295/13 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227727 | Hamrick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Augusta University Research Institute, Inc. (Augusta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark Hamrick (Evans, Georgia); Carlos Isales (Augusta, Georgia); Iryna Lebedyeva (Augusta, Georgia) |
| ABSTRACT | Provided herein are compounds that inhibit IDO1 and methods of use thereof. Also provided are pharmaceutical compositions and medicaments that include the compounds described herein as well as methods of treating sarcopenia or age-related muscle loss. |
| FILED | Wednesday, January 19, 2022 |
| APPL NO | 17/579505 |
| CURRENT CPC | Heterocyclic Compounds C07D 311/06 (20130101) C07D 317/60 (20130101) Original (OR) Class C07D 405/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227734 | Che et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Jianwei Che (Sharon, Massachusetts); Nathanael S. Gray (Stanford, California); Tinghu Zhang (Brookline, Massachusetts); Baishan Jiang (Brookline, Massachusetts); Yang Gao (Boston, Massachusetts); Nicholas Paul Kwiatkowski (Brookline, Massachusetts) |
| ABSTRACT | Provided herein are bifunctional compounds with a moiety (e.g., lenalidomide, thalidomide) that is a binder of an E3 ubiquitin ligase (e.g., Cereblon) and another moiety that is a binder of a target protein (e.g., kinase (e.g., CDK (e.g., CDK9 and/or CDK12))) to induce degradation of the target protein CDK9 and/or CDK12. Also provided are pharmaceutical compositions comprising the bifunctional compounds, and methods of treating and/or preventing diseases (e.g., proliferative diseases, such as cancers (e.g., ovarian cancer, breast cancer, or prostate cancer))). Provided also are methods of inducing the degradation of the target protein (e.g., kinase (e.g., CDK (e.g., CDK9 and/or CDK12))), and methods of inducing apoptosis in a cell in a biological sample or subject by administering the bifunctional compound or composition described herein. |
| FILED | Thursday, April 23, 2020 |
| APPL NO | 17/604852 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 47/555 (20170801) Heterocyclic Compounds C07D 401/14 (20130101) Original (OR) Class C07D 417/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227735 | BHANOT et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| INVENTOR(S) | Purnima BHANOT (New Brunswick, New Jersey); David J. AUGERI (New Brunswick, New Jersey); John A. GILLERAN (New Brunswick, New Jersey); Raheel FONDEKAR (New Brunswick, New Jersey) |
| ABSTRACT | The invention provides a compound of formula I: (I) or a pharmaceutically acceptable salt thereof, wherein R1-R5 Y have any of the values described in the specification, as well as compositions comprising a compound of formula I. The compounds are useful to treat malaria. |
| FILED | Wednesday, April 22, 2020 |
| APPL NO | 17/605732 |
| CURRENT CPC | Heterocyclic Compounds C07D 401/14 (20130101) Original (OR) Class C07D 409/14 (20130101) C07D 471/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227740 | Ungashe et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tosk, Inc. (Mountain View, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Solomon B. Ungashe (Mountain View, California); William A. Garland (Mountain View, California); Stephen D. Yanofsky (Mountain View, California); Brian D. Frenzel (Mountain View, California); Philip Liaw (Mountain View, California); Annie L. Lennek (Mountain View, California) |
| ABSTRACT | RAS modulating compounds and methods of using the same are provided. The compounds find use in modulating the activity of a target RAS in a sample. The target RAS can be a mutant RAS that is implicated in a disease of interest. In some cases, the subject compounds can inhibit the growth of cancer cells whose progression is driven by kRAS or a mutated kRAS. Methods of treating a subject for a RAS driven disease including administering a therapeutically effective amount of the subject compound are provided. Also provided are pharmaceutical compositions and kits which include the subject compounds. |
| FILED | Monday, April 13, 2020 |
| APPL NO | 17/439989 |
| CURRENT CPC | Heterocyclic Compounds C07D 239/84 (20130101) C07D 401/04 (20130101) C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 405/04 (20130101) C07D 405/14 (20130101) Original (OR) Class C07D 413/04 (20130101) C07D 413/14 (20130101) C07D 471/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227750 | Tweardy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Baylor College of Medicine (Houston, Texas); The United States of America, as represented by the Secretary, Department of Health and Human Servic (Bethesda, Maryland) |
| ASSIGNEE(S) | Baylor College of Medicine (Houston, Texas); The United States of America, as represented by the Secretary, Department of Health and Human Servic (Bethesda, Maryland) |
| INVENTOR(S) | David J. Tweardy (Houton, Texas); Moses M. Kasembeli (Houston, Texas); Marvin X. Xu (Shanghai, China PRC); Josh Milner (Bethesda, Maryland); Claire Elizabeth Bocchini (Houston, Texas) |
| ABSTRACT | Embodiments of the invention include methods of preventing and/or reducing the risk or severity of an allergic reaction in an individual. In some embodiments, particular small molecules are employed for prevention and/or reduction in the risk or severity of anaphylaxis. In at least particular cases, the small molecules are inhibitors of STAT3. In some cases, the small molecule comprises N-(1′,2-dihydroxy-1,2′-binaphthalen-4′-yl)-4-methoxybenzenesulfonamide. |
| FILED | Thursday, January 27, 2022 |
| APPL NO | 17/649133 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/196 (20130101) A61K 31/357 (20130101) A61K 31/381 (20130101) A61K 31/403 (20130101) A61K 31/415 (20130101) A61K 31/505 (20130101) A61K 31/4196 (20130101) A61K 45/06 (20130101) Acyclic or Carbocyclic Compounds C07C 311/08 (20130101) C07C 311/21 (20130101) C07C 311/29 (20130101) Heterocyclic Compounds C07D 213/71 (20130101) C07D 215/36 (20130101) C07D 239/545 (20130101) C07D 319/18 (20130101) C07D 333/34 (20130101) C07D 401/12 (20130101) C07D 409/12 (20130101) C07D 413/12 (20130101) C07D 417/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227772 | BALLATORE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Carlo BALLATORE (San Diego, California); Kurt R. BRUNDEN (Media, Pennsylvania); Killian OUKOLOFF (San Diego, California); Virgina M.Y. LEE (Philadelphia, Pennsylvania); John Q. TROJANOWSKI (Philadelphia, Pennsylvania); Amos B. SMITH, III (Merion, Pennsylvania) |
| ABSTRACT | The present disclosure provides compounds of formula (I) or a pharmaceutically acceptable salt or stereoisomer thereof, wherein R1-R6 are defined herein. Also provided are compositions comprising a compound described herein and a pharmaceutically effective excipient, methods of stabilizing microtubules in a patient comprising administering to the patient a microtubule-stabilizing amount of a compound described herein, methods of treating cancer in a patient comprising administering to the patient a therapeutically effective amount of a compound described herein, and methods of treating a neurodegenerative disease in a patient comprising administering to the patient a therapeutically effective amount of a compound described herein. |
| FILED | Thursday, May 07, 2020 |
| APPL NO | 17/609089 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227803 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yong Zhang (Los Angeles, California); Zhefu Dai (Los Angeles, California); Xiao-Nan Zhang (Los Angeles, California) |
| ABSTRACT | This disclosure provides a method of synthesis of 4′-thioribose NAD+ and analogues thereof, using an efficient chemoenzymatic approach. Also provided are methods of inhibiting the CD38 enzyme and compounds including 4′-thioribose NAD+ and compounds related thereto. |
| FILED | Friday, October 04, 2019 |
| APPL NO | 17/281424 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7076 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/20 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227806 | Schiffer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Celia A. Schiffer (Shrewsbury, Massachusetts); Akbar Ali (Westborough, Massachusetts); Jacqueto Zephyr (Worcester, Massachusetts); Ashley N. Matthew (Worcester, Massachusetts); Nageswara R. Desaboini (Worcester, Massachusetts) |
| ABSTRACT | The invention provides novel classes of HCV therapeutics that are orally available, safe and effective HCV NS3/4A protease inhibitors and are less susceptible to drug resistance than existing therapeutics. The invention also relates to pharmaceutical composition of these compounds and methods of preparation and use thereof. |
| FILED | Friday, June 05, 2020 |
| APPL NO | 17/607886 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 5/0804 (20130101) Original (OR) Class C07K 5/1016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227814 | TAL-GAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, REN (Reno, Nevada); The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yftah TAL-GAN (Reno, Nevada); Gee W. LAU (Urbana, Illinois); Yifang YANG (Reno, Nevada) |
| ABSTRACT | Disclosed herein are compositions, methods of treatment and kits for treating Streptococcus Pneumoniae infections. In some examples, compositions including cyclic dominant negative competence stimulating peptide analogs are disclosed and used for treating Streptococcus Pneumoniae infections. |
| FILED | Thursday, May 21, 2020 |
| APPL NO | 17/613272 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 45/06 (20130101) Peptides C07K 7/64 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227815 | Siahaan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Kansas (Lawrence, Kansas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Teruna J. Siahaan (Lawrence, Kansas); Brian Matthew Kopec (Lawrence, Kansas); Kavisha Raneendri Ulapane (Battaramulla, Sri Lanka) |
| ABSTRACT | Compounds, compositions, and methods are provided that are useful in treating brain diseases by effecting delivery across the blood brain barrier of molecules that otherwise do not (or insignificantly) pass across the blood brain barrier, where compounds of the present technology include but are not limited to cyclo(1,6)SHAVSS (“HAVN1”), cyclo(1,5)SHAVS (“HAVN2”), cyclo(1, 8)TPP V SHAV (“cyclic ADTHAV”), cyclo(1,6)ADTPPV (“ADTN1”), cyclo(1,5)DTPPV (“ADTN2”), acetyl-TPPVSHAV-NH2 (“linear ADTHAV”), and pharmaceutically acceptable salts thereof. |
| FILED | Sunday, June 21, 2020 |
| APPL NO | 17/615032 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/12 (20130101) A61K 45/06 (20130101) Peptides C07K 7/06 (20130101) C07K 7/64 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227819 | Missiakas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois); Janssen Pharmaceuticals, Inc. (Titusville, New Jersey) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois); Janssen Pharmaceuticals, Inc. (Titusville, New Jersey) |
| INVENTOR(S) | Dominique Missiakas (Chicago, Illinois); Olaf Schneewind (Chicago, Illinois); Carla Emolo (Chicago, Illinois); Lena Thomer (Chicago, Illinois); Molly McAdow (Chicago, Illinois); Jeroen Geurtsen (Leiden, Netherlands); Mark De Been (Leiden, Netherlands) |
| ABSTRACT | Embodiments concern methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. Aspects include methods and compositions for providing a passive immune response against the bacteria. In certain embodiments, the methods and compositions involve an antibody that binds Coagulase (Coa). Further aspects relate to immunogenic compositions comprising at least one Staphylococcal coagulase R Domain, wherein the R Domain is 80% identical in sequence to a R Domain. |
| FILED | Tuesday, December 21, 2021 |
| APPL NO | 17/645344 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/40 (20130101) A61K 39/085 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/31 (20130101) Original (OR) Class C07K 16/40 (20130101) C07K 16/1271 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227824 | SHALEM et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Ophir H. SHALEM (Philadelphia, Pennsylvania); Katelyn SWEENEY (Philadelphia, Pennsylvania) |
| ABSTRACT | The present disclosure is directed to the use of SRR1 domain-containing protein (SRRD) or active fragment thereof to reduce protein aggregation, such as that occurring in neurodegenerative diseases. |
| FILED | Tuesday, June 23, 2020 |
| APPL NO | 17/596622 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/16 (20180101) A61P 25/28 (20180101) Peptides C07K 14/4702 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227826 | Thallapuranam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
| INVENTOR(S) | Suresh Kumar Thallapuranam (Fayetteville, Arkansas); Shilpi Agrawal (Fayetteville, Arkansas); Ravi Kumar Gundampati (Fayetteville, Arkansas); Srinivas Jayanthi (Fayetteville, Arkansas); Tengjiao Wang (Fayetteville, Arkansas); Jake Jones (Fayetteville, Arkansas); Olivia Kolenc (Fayetteville, Arkansas); Ngoc Lam (Fayetteville, Arkansas); Isabelle Niyonshuti (Fayetteville, Arkansas); Kartik Balachandran (Fayetteville, Arkansas); Kyle Quinn (Fayetteville, Arkansas); Jingyi Chen (Fayetteville, Arkansas) |
| ABSTRACT | Engineered FGF1 and FGF2 polypeptides, polynucleotides encoding these polypeptides and DNA constructs, vectors and compositions including these engineered polypeptides are provided herein. The engineered FGF1 and FGF2 polypeptides are more stable than their wild-type counterparts and may be more effective at treating a variety of conditions that FGF1 and FGF2 are useful for treating such as wound healing. |
| FILED | Friday, January 28, 2022 |
| APPL NO | 17/587889 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 38/00 (20130101) Peptides C07K 14/501 (20130101) Original (OR) Class C07K 14/503 (20130101) C07K 2319/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227844 | Nussenzweig et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Rockefeller University (New York, New York) |
| ASSIGNEE(S) | The Rockefeller University (New York, New York) |
| INVENTOR(S) | Michel Nussenzweig (New York, New York); Zijun Wang (New York, New York) |
| ABSTRACT | This disclosure provides novel neutralizing anti-SARS-CoV-2 antibodies or antigen-binding fragments thereof. The disclosed anti-SARS-CoV-2 antibodies constitute a novel therapeutic strategy in protection from SARS-CoV-2 infections. |
| FILED | Thursday, January 13, 2022 |
| APPL NO | 17/575246 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 45/06 (20130101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/31 (20130101) C07K 2317/35 (20130101) C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/165 (20130101) G01N 2800/26 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227845 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); University of Maryland, Baltimore (Baltimore, Maryland); The United States of America, as Represented by the Secretary, Department of Health and Human Servic (Bethesda, Maryland); International AIDS Vaccine Initiative (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yuxing Li (Boyds, Maryland); James Steinhardt (Westminster, Maryland); Javier Guenaga (San Diego, California); John R. Mascola (Rockville, Maryland); Tae-Wook Chun (North Bethesda, Maryland); Susan Moir (Washington, District of Columbia); Chi-I Chiang (Rockville, Maryland) |
| ABSTRACT | The present invention provides a multispecific anti-HIV antibody that binds to multiple epitopes on HIV envelope protein, wherein the antibody comprises: i. an amino acid sequence that binds to a V1/V2 apex glycan epitope; ii. an amino acid sequence that binds to a V3-base glycan region epitope; iii. an amino acid sequence that binds to a CD4 binding site (CD4bs) epitope; iv. an amino acid sequence that binds to a gp120/gp41 interface epitope; and v. an amino acid sequence that binds to a membrane proximal external region (MPER) epitope. |
| FILED | Friday, October 18, 2019 |
| APPL NO | 17/285956 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) Peptides C07K 16/1045 (20130101) C07K 16/1063 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227846 | Wilson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Temple University-of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania); LANKENAU INSTITUTE OF MEDICAL RESEARCH (Wynnewood, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Cagla Tukel Wilson (Huntingdon Valley, Pennsylvania); Scott Dessain (Wynnewood, Pennsylvania) |
| ABSTRACT | The present invention features compositions comprising an anti-amyloid antibody and methods of treating microbial infection and treating or preventing microbial biofilms using the composition. |
| FILED | Thursday, January 20, 2022 |
| APPL NO | 17/579952 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Peptides C07K 16/1228 (20130101) C07K 16/1232 (20130101) C07K 16/1235 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227852 | Quiroz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts); Banner Health (Phoenix, Arizona); The Schepens Eye Research Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yakeel T. Quiroz (Charlestown, Massachusetts); Joseph F. Arboleda-Velasquez (Newton, Massachusetts); Eric Reiman (Phoenix, Arizona); Francisco Lopera (Medellin, Colombia) |
| ABSTRACT | Methods and compositions for preventing or treating cognitive decline associated with dementia and/or mild cognitive impairment and/or neurodegeneration using antibodies, peptides, fusion proteins, or genome editing systems that modulate HSPG/heparin binding affinities of ApoE. |
| FILED | Thursday, May 28, 2020 |
| APPL NO | 17/614008 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Peptides C07K 14/775 (20130101) C07K 16/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227853 | Seder et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Robert Seder (Chevy Chase, Maryland); Lawrence Wang (Bethesda, Maryland); Rachel Vistein (Bethesda, Maryland); Joseph Francica (Bethesda, Maryland) |
| ABSTRACT | Antibodies and antigen binding fragments that specifically bind to P. falciparum circumsporozoite protein are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. The disclosed antibodies, antigen binding fragments, nucleic acids and vectors can be used, for example, to inhibit a P. falciparum infection. |
| FILED | Monday, May 04, 2020 |
| APPL NO | 17/608381 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6843 (20170801) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 33/06 (20180101) Peptides C07K 16/205 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56905 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227855 | TSIROS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Divyabharathy TSIROS (Dracut, Massachusetts); Matthew NUGENT (Bedford, Massachusetts) |
| ABSTRACT | Described herein is a method of treating a subject in need of treatment for pathological angiogenesis including administering to the subject a glycosaminoglycan linked either covalently or noncovalently to an anti-VEGF antibody, an anti-VEGF antibody fragment, an anti-VEGF protein, an anti-VEGF peptide, or an anti-VEGF aptamer. Also included is a glycosaminoglycan linked either covalently or noncovalently to an anti-VEGF antibody, an anti-VEGF antibody fragment, an anti-VEGF protein, an anti-VEGF peptide, or an anti-VEGF aptamer. |
| FILED | Wednesday, April 22, 2020 |
| APPL NO | 17/606173 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/61 (20170801) A61K 47/6807 (20170801) A61K 47/6845 (20170801) Peptides C07K 16/22 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227882 | Sonenshein et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts) |
| INVENTOR(S) | Gail Sonenshein (Brookline, Massachusetts); Nora Mineva (Brighton, Massachusetts) |
| ABSTRACT | Provided herein are proteins that inhibit both the metalloprotease activity and disintegrin activity of human wherein the protein comprises an antigen-binding domain that: (i) binds specifically to human ADAM8; and (ii) binds to an epitope within human ADAM8 that includes at least one amino acid within the sequence of SEQ ID NO: 1, nucleic acids, vectors, compositions, and methods of use thereof (e.g., methods of treatment and methods of diagnosing). |
| FILED | Friday, May 29, 2020 |
| APPL NO | 17/615312 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/2896 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57484 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227886 | Buelow et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Albert Einstein College of Medicine (Bronx, New York) |
| ASSIGNEE(S) | Albert Einstein College of Medicine (Bronx, New York) |
| INVENTOR(S) | Hannes E. Buelow (Bronx, New York); Ulrich G. Steidl (New Rochelle, New York); Steven C. Almo (Pelham, New York); Robert A. Townley (Shorewood, Wisconsin); Richard Pisczcaztowski (Rutherford, New Jersey); Ron Seidel, III (Bronx, New York) |
| ABSTRACT | This disclosure relates to compositions and methods of identifying, isolating, and modulating cells and tissues based on their cellular glycosaminoglycan pattern. In some aspects, provided are anti-GAG motif antibodies or antigen-binding fragments thereof and their use for determining a glycosaminoglycan (GAG) glycotype for a cell. Also provided are methods of isolating cells, identifying cells, detecting a disease or disorder, and/or treating a disease or disorder based on a cellular glycotype. |
| FILED | Tuesday, May 26, 2020 |
| APPL NO | 17/612665 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6815 (20170801) A61K 47/6835 (20170801) A61K 49/0058 (20130101) Peptides C07K 16/44 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) G01N 2400/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227937 | Sletten et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ellen M. Sletten (Los Angeles, California); Daniel A. Estabrook (Los Angeles, California); John O. Chapman (Auburn, Alabama) |
| ABSTRACT | Disclosed herein are amphiphilic polymers and hierarchical structures (e.g., emulsions) comprising said polymer. Also disclosed herein are methods of using the polymers and hierarchical structure disclosed herein. |
| FILED | Wednesday, May 20, 2020 |
| APPL NO | 17/612931 |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/0233 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220228111 | Singec et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ilyas SINGEC (Rockville, Maryland); Tao DENG (Rockville, Maryland); Anton SIMEONOV (Rockville, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ilyas Singec (Rockville, Maryland); Tao Deng (Rockville, Maryland); Anton Simeonov (Rockville, Maryland) |
| ABSTRACT | Methods for Generating Neural Crest-Like Cells and Nociceptor-Like Cells from Human Pluripotent Stem Cells are Provided Along with the Related Compositions. |
| FILED | Friday, April 24, 2020 |
| APPL NO | 17/605876 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0284 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/062 (20130101) Original (OR) Class C12N 2500/38 (20130101) C12N 2501/13 (20130101) C12N 2506/45 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220228117 | Childs et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Richard W. Childs (Rockville, Maryland); David S.J. Allan (Rockville, Maryland) |
| ABSTRACT | Disclosed herein are method of producing NK cells that include one or more heterologous nucleic acids. The methods include culturing a population of isolated NK cells in the presence of one or more cytokines to produce a population of activated NK cells. The population of activated NK cells are transduced with a viral vector comprising the one or more heterologous nucleic acids, for example by contacting the activated NK cells with viral particles including the viral vector. The resulting transduced NK cells are then cultured in the presence of one or more cytokines, and optionally in the presence of irradiated feeder cells, to produce a population of expanded transduced NK cells. Also disclosed are methods of treating a subject with a disorder (such as a tumor or hyperproliferative disorder) by administering to the subject NK cells produced by the methods described herein. |
| FILED | Monday, March 07, 2022 |
| APPL NO | 17/688435 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) C12N 5/0646 (20130101) Original (OR) Class C12N 15/867 (20130101) C12N 2501/505 (20130101) C12N 2501/599 (20130101) C12N 2501/999 (20130101) C12N 2501/2302 (20130101) C12N 2502/30 (20130101) C12N 2502/99 (20130101) C12N 2502/1135 (20130101) C12N 2510/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220228118 | Slukvin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Igor Slukvin (Verona, Wisconsin); Gene lchiro Uenishi (Madison, Wisconsin) |
| ABSTRACT | Methods, kits and compositions for differentiating pluripotent stem cells into cells of endothelial and hematopoietic lineages are disclosed. |
| FILED | Thursday, April 07, 2022 |
| APPL NO | 17/715889 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0056 (20130101) C12N 5/069 (20130101) C12N 5/0636 (20130101) C12N 5/0647 (20130101) Original (OR) Class C12N 5/0695 (20130101) C12N 2500/02 (20130101) C12N 2501/16 (20130101) C12N 2501/115 (20130101) C12N 2501/155 (20130101) C12N 2501/165 (20130101) C12N 2502/1394 (20130101) C12N 2506/02 (20130101) C12N 2506/45 (20130101) C12N 2533/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220228121 | Stout et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew Stout (Medford, Massachusetts); David L. Kaplan (Medford, Massachusetts) |
| ABSTRACT | Provided herein are genetically engineered mammalian cells that endogenously express one or more phytochemicals, vitamins, or therapeutic agents and suitable for use in a cultured meat product. Methods of making and using the genetically engineered mammalian cells and the cultured meat products are also provided. |
| FILED | Monday, June 01, 2020 |
| APPL NO | 17/615578 |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 13/42 (20160801) Peptides C07K 16/241 (20130101) C07K 2317/569 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0659 (20130101) Original (OR) Class C12N 9/1085 (20130101) C12N 2510/02 (20130101) Enzymes C12Y 205/01032 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220228124 | DE LA PUENTE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SANFORD HEALTH (Sioux Falls, South Dakota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pilar DE LA PUENTE (Sioux Falls, South Dakota); Somshuvra BHATTACHARYA (Sioux Falls, South Dakota); Kristin CALAR (Sioux Falls, South Dakota) |
| ABSTRACT | The disclosure provides three-dimensional cross-linked scaffolds generated from peripheral blood plasma, and methods for making and using such scaffolds. |
| FILED | Saturday, June 15, 2019 |
| APPL NO | 17/612142 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) C12N 5/0693 (20130101) Original (OR) Class C12N 2500/14 (20130101) C12N 2500/84 (20130101) C12N 2513/00 (20130101) C12N 2533/56 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220228129 | Schaffer et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David V. Schaffer (Danville, California); Christopher Barnes (Oakland, California); David Stephen Ojala (Berkeley, California) |
| ABSTRACT | The present disclosure provides an in vitro mammalian cell that is genetically modified to provide for enhanced production of adeno-associated virus (AAV) virions. The mammalian cells can be used to produce AAV virions, e.g., recombinant AAV virions that include a heterologous nucleic acid encoding a gene product; the present disclosure thus provides methods for producing an AAV virion, which may be a recombinant AAV virion. |
| FILED | Wednesday, April 22, 2020 |
| APPL NO | 17/605387 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0687 (20130101) C12N 7/00 (20130101) Original (OR) Class C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/63 (20130101) C12N 15/85 (20130101) C12N 15/86 (20130101) C12N 15/1058 (20130101) C12N 2310/20 (20170501) C12N 2510/02 (20130101) C12N 2750/14142 (20130101) C12N 2750/14152 (20130101) C12N 2800/80 (20130101) C12N 2800/107 (20130101) C12N 2840/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220228131 | Stafford et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Darrel W. Stafford (Carrboro, North Carolina); Tao Li (San Diego, California) |
| ABSTRACT | The present invention relates to methods and compositions for improving the productivity of recombinant vitamin K dependent protein expression in host cells. |
| FILED | Thursday, August 26, 2021 |
| APPL NO | 17/412827 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) Original (OR) Class C12N 9/50 (20130101) C12N 9/64 (20130101) C12N 9/88 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) C12Q 2600/172 (20130101) Enzymes C12Y 101/04001 (20130101) C12Y 304/21006 (20130101) C12Y 401/0109 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220228141 | Czech et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael P. Czech (Westborough, Massachusetts); Batuhan Orbay Yenilmez (Shrewsbury, Massachusetts); Anastasia Khvorova (Westborough, Massachusetts) |
| ABSTRACT | This disclosure relates to novel DGAT2 targeting sequences. Novel DGAT2 targeting oligonucleotides for the treatment of non-alcoholic fatty liver disease (NAFLD) and lipodystrophy syndromes (or metabolic syndrome) are also provided. |
| FILED | Monday, November 22, 2021 |
| APPL NO | 17/532636 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/315 (20130101) C12N 2310/351 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220228148 | ROMESBERG et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Floyd E. ROMESBERG (La Jolla, California); Anne Xiaozhou ZHOU (La Jolla, California); Kai SHENG (La Jolla, California) |
| ABSTRACT | Provided herein are eukaryotic semi-synthetic organisms and their methods of use and manufacture. |
| FILED | Wednesday, March 30, 2022 |
| APPL NO | 17/709041 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220228168 | Borrajo et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Jacob Borrajo (Cambridge, Massachusetts); Paul Blainey (Cambridge, Massachusetts); Mohamad Najia (Cambridge, Massachusetts); Hong Anh Anna Le (Cambridge, Massachusetts); FuNien Tsai (Cambridge, Massachusetts) |
| ABSTRACT | Compositions and methods for inducing and isolating virus-like particles (VLPs), and for allowing real-time assessment of VLP-captured analytes obtained from targeted living mammalian cells, are provided. |
| FILED | Tuesday, April 28, 2020 |
| APPL NO | 17/607097 |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 15/1072 (20130101) C12N 2740/13023 (20130101) C12N 2740/13031 (20130101) C12N 2740/16023 (20130101) C12N 2740/16031 (20130101) C12N 2740/16222 (20130101) C12N 2750/14123 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220228196 | Church et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | George M. Church (Brookline, Massachusetts); Je-Hyuk Lee (Allston, Massachusetts); Richard C. Terry (Carlisle, Massachusetts); Evan R. Daugharthy (Cambridge, Massachusetts) |
| ABSTRACT | Methods of making a three-dimensional matrix of nucleic acids within a cell is provided. |
| FILED | Wednesday, March 30, 2022 |
| APPL NO | 17/708050 |
| CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6844 (20130101) C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220228198 | White et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Chan Zuckerberg Biohub, Inc. (San Francisco, California); The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Adam K. White (Stanford, California); Huy Q. Nguyen (Stanford, California); Feiqiao Brian Yu (San Francisco, California); Tyler Shimko (Stanford, California); Polly M. Fordyce (Stanford, California); Nadya Andini (Stanford, California); Samuel Yang (Stanford, California); Gaeun Kim (Stanford, California) |
| ABSTRACT | Methods for characterizing a population of microbes in a sample are described. The methods include: amplifying microbial polynucleotides obtained from the sample to form a plurality of amplicons and combining the amplicons with a plurality of microbeads, wherein each of the microbeads has a lanthanide spectral signature paired with the sequence of capture polynucleotides immobilized on the microbead. At least some of the capture polynucleotides comprise a sequence substantially complementary to a microbe-identifying sequence in one or more amplicons, such that at least some amplicons are captured onto beads by the capture polynucleotides and the microbe can be identified based on the lanthanide spectral signature of with which the capture polynucleotide is paired. Further described are methods for the identification of pathogens present in a sample by evaluating patterns of hybridization of a capture oligonucleotide to amplicons. Microbead compositions and methods for the preparation thereof are also described. |
| FILED | Wednesday, May 27, 2020 |
| APPL NO | 17/613676 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Original (OR) Class C12Q 1/6816 (20130101) C12Q 1/6834 (20130101) C12Q 2600/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220228964 | Knox et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Wayne H. Knox (Rochester, New York); Gregory Madejski (Albion, New York); James Lionel McGrath (Rochester, New York) |
| ABSTRACT | A device, system and method for the detection and screening of plastic microparticles in a sample is disclosed. A nanoporous silicon nitride membrane is used to entrap plastic microparticles contained in the sample. The sample may be a water sample, an air sample, or other liquid or gas sample. The entrapped plastic microparticles are then heated or otherwise processed on the nanoporous silicon nitride membrane. An imaging system observes the nanoporous silicon nitride membrane with tic entrapped plastic microparticles to determine the type and quantity of the various plastic microparticles that are entrapped on the membrane. |
| FILED | Wednesday, January 19, 2022 |
| APPL NO | 17/579515 |
| CURRENT CPC | Separation B01D 61/20 (20130101) B01D 71/02 (20130101) B01D 2311/103 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/0612 (20130101) Original (OR) Class G01N 2015/0681 (20130101) G01N 2015/0693 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220228965 | Sulchek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Todd Sulchek (Atlanta, Georgia); Alexander Alexeev (Atlanta, Georgia); Bushra Tasadduq (Atlanta, Georgia) |
| ABSTRACT | A microchannel for processing cells by compression of the cells including an inlet, ridges and an outlet. Each ridge including a compressive surface and a cell adhesion entity. The outlet configured to remove at least one of a first portion of the cells and a second portion of the cells from the microchannel. Each ridge oriented at an angle of from 25 degrees to 70 degrees relative to a center axis of the microchannel. The cell adhesion entity configured such that the first portion of the cells has a first adhesion property relative to the cell adhesion entity to follow a first trajectory through the microchannel. The cell adhesion entity further configured such that the second portion of the cells has a second adhesion property relative to the cell adhesion entity to follow a second trajectory through the microchannel. The first trajectory is different from the second trajectory. |
| FILED | Friday, February 04, 2022 |
| APPL NO | 17/650033 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 3/502776 (20130101) B01L 2200/0652 (20130101) B01L 2200/0668 (20130101) B01L 2300/16 (20130101) B01L 2300/0877 (20130101) B01L 2400/086 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/34 (20130101) G01N 15/1056 (20130101) Original (OR) Class G01N 33/5005 (20130101) G01N 2015/1006 (20130101) G01N 2015/1081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220228987 | Boppart et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen A. Boppart (Champaign, Illinois); Haohua Tu (Savoy, Illinois); Sixian You (Urbana, Illinois) |
| ABSTRACT | A method is provided for characterizing a biological sample having a plurality of fluorophores, including a red fluorophore and a blue fluorophore, comprises exciting the red fluorophore via absorption of a photon order of n by a single wavelength band of light that has longer wavelengths than a typical wavelength band of light known to excite the red fluorophore would have. The method further comprises exciting the blue fluorophore substantially via absorption of a photon order of n+1 by the single wavelength band of light. The method also comprises simultaneously detecting light emitted by the red fluorophore and the blue fluorophore. The method further comprises creating an image or a temporal series for sensing from the light detected in the plurality of orthogonal colors. |
| FILED | Tuesday, May 05, 2020 |
| APPL NO | 17/621922 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) Original (OR) Class G01N 2201/06113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220229005 | Potyrailo et al. |
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| FUNDED BY |
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| APPLICANT(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Radislav Alexandrovich Potyrailo (Niskayuna, New York); Emad Andarawis Andarawis (Ballston Lake, New York); Naresh Kesavan Rao (Clifton Park, New York) |
| ABSTRACT | A monolithic gas-sensing chip assembly for sensing a gas analyte includes a sensing material to detect the gas analyte, a sensing system including a resistor-capacitor electrical circuit, and a heating element. A sensing circuit measures an electrical response of the sensing system to an alternating electrical current applied to the sensing system at (a) one or more different frequencies, or (b) one or more different resistor-capacitor configurations of the system. One or more processors control a low detection range of the system to the gas, a high detection range of the system to the gas, a linearity of a response of the system to the gas, a dynamic range of measurements of the gas by the system, a rejection of interfering gas analytes by the system, a correction for aging or poisoning of the system, or a rejection of ambient interferences that may affect the electrical response of the system. |
| FILED | Thursday, April 07, 2022 |
| APPL NO | 17/715693 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/123 (20130101) Original (OR) Class G01N 27/226 (20130101) G01N 27/228 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220229014 | Pourmand et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nader Pourmand (San Mateo, California); Boaz Vilozny (Santa Cruz, California); Paolo Actis (London, United Kingdom); R. Adam Seger (Santa Cruz, California) |
| ABSTRACT | Disclosed are methods and devices for detection of ion migration and binding, utilizing a nanopipette adapted for use in an electrochemical sensing circuit. The nanopipette may be functionalized on its interior bore with metal chelators for binding and sensing metal ions or other specific binding molecules such as boronic acid for binding and sensing glucose. Such a functionalized nanopipette is comprised in an electrical sensor that detects when the nanopipette selectively and reversibly binds ions or small molecules. Also disclosed is a nanoreactor, comprising a nanopipette, for controlling precipitation in aqueous solutions by voltage-directed ion migration, wherein ions may be directed out of the interior bore by a repulsing charge in the bore. |
| FILED | Tuesday, December 21, 2021 |
| APPL NO | 17/557549 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/021 (20130101) B01L 3/50273 (20130101) B01L 2300/0896 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 35/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3277 (20130101) G01N 27/44791 (20130101) Original (OR) Class G01N 33/48721 (20130101) Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 60/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220229026 | Gentry et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew S. Gentry (Lexington, Kentucky); Ronald Bruntz (Lexington, Kentucky); Ramon C. Sun (Lexington, Kentucky) |
| ABSTRACT | Provided herein are methods of measuring glycogen and methods of diagnosing a disease. One method of measuring includes separating sugar monomers and sugar phosphates using gas-chromatography, and analyzing the monomers and phosphates using mass spectrometry. Another method of measuring includes adding an isoamylase to a sample, the isoamylase cleaving glucose chains from glycogen; applying a matrix-assisted laser desorption ionization (MALDI) ionization matrix to the sample; and analyzing the samples using matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS). The method of diagnosing a disease includes determining an amount and location of glycogen accumulation in a subject; and diagnosing a disease when over-accumulation of glycogen is determined. |
| FILED | Thursday, January 20, 2022 |
| APPL NO | 17/580513 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/7206 (20130101) Original (OR) Class G01N 33/66 (20130101) G01N 2030/025 (20130101) G01N 2333/944 (20130101) G01N 2400/48 (20130101) G01N 2570/00 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/26 (20130101) H01J 49/0031 (20130101) H01J 49/164 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220229044 | Feldman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Feldman (Cambridge, Massachusetts); Paul Blainey (Cambridge, Massachusetts); Avtar Singh (Cambridge, Massachusetts); Rebecca Carlson (Cambridge, Massachusetts) |
| ABSTRACT | The subject matter disclosed herein is generally directed to methods and systems for screening phenotypes associated with genetic elements and identifying genetic elements at the single-cell level using optical barcodes. A major advantage offered by this approach is the ability to screen for any cellular phenotype that can be identified by high-resolution microscopy—including live-cell phenotypes, protein localization, or highly multiplexed expression profile and mRNA localization in conjunction with a large array of genetic elements applied as a pool in a single test volume. |
| FILED | Tuesday, May 14, 2019 |
| APPL NO | 17/055502 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 15/86 (20130101) C12N 2310/20 (20170501) C12N 2320/12 (20130101) C12N 2740/15043 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5026 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220229061 | CARTER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HDT Bio Corp. (Seattle, Washington); University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Darrick CARTER (Seattle, Washington); Jiho KIM (Seattle, Washington); Andre LIEBER (Seattle, Washington) |
| ABSTRACT | The disclosure provides methods of diagnosing, prognosing and stratifying cancers in a patient, comprising detecting elevated expression of desmoglein-2 (DSG-2) in a sample of the cancer and referencing that level to historic data to determine treatment regimen, stage, and prognosis of a patient. |
| FILED | Thursday, April 07, 2022 |
| APPL NO | 17/715092 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44739 (20130101) G01N 33/543 (20130101) G01N 33/57449 (20130101) Original (OR) Class G01N 2333/47 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220229067 | BIRNBAUM et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | MICHAEL EDWARD BIRNBAUM (STANFORD, California); JUAN LUIS MENDOZA (REDWOOD CITY, California); MICHAEL THOMAS BETHUNE (PASADENA, California); DAVID BALTIMORE (PASADENA, California); KENAN CHRISTOPHER GARCIA (MENLO PARK, California) |
| ABSTRACT | Compositions and methods are provided for the identification of peptide sequences that are ligands for a T cell receptor (TCR) of interest, in a given MHC context. |
| FILED | Friday, July 16, 2021 |
| APPL NO | 17/378310 |
| CURRENT CPC | Peptides C07K 14/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6845 (20130101) Original (OR) Class G01N 2333/7051 (20130101) G01N 2333/70539 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220229140 | WANG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cornell University Center for Technology Licensing (CTL) (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University Center for Technology Licensing (CTL) (Ithaca, New York) |
| INVENTOR(S) | Yi WANG (New York, New York); Zhe LIU (New York, New York); Jinwei ZHANG (New York, New York); Qihao ZHANG (New York, New York); Junghun CHO (New York, New York); Pascal SPINCEMAILLE (New York, New York) |
| ABSTRACT | Exemplary methods for quantitative mapping of physical properties, systems and computer-accessible medium can be provided to generate images of tissue magnetic susceptibility, transport parameters and oxygen consumption from magnetic resonance imaging data using the Bayesian inference approach, which minimizes a data fidelity term under a constraint of a structure prior knowledge. The data fidelity term is constructed directly from the magnetic resonance imaging data. The structure prior knowledge can be characterized from known anatomic images using image feature extraction operation or artificial neural network. Thus, according to the exemplary embodiment, system, method and computer-accessible medium can be provided for determining physical properties associated with at least one structure. |
| FILED | Thursday, May 28, 2020 |
| APPL NO | 17/614277 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 5/7221 (20130101) A61B 5/7267 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5608 (20130101) Original (OR) Class G01R 33/56536 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/10088 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220229441 | Reiserer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ronald S. Reiserer (Nashville, Tennessee); John P. Wikswo (Brentwood, Tennessee) |
| ABSTRACT | A robot for transporting a biodevice from one place to another place, comprising a body for carrying the biodevice; a driving assembly for driving the body in omnidirectional motion; a sensing unit for sensing at least a position and orientation of the body; and a control unit coupled to the driving assembly and the sensing unit for generating one or more control signals based on at least the sensed position and orientation of the body to drive the driving assembly so as to move the body to a desired place and to arrive with the correct orientation. |
| FILED | Wednesday, January 19, 2022 |
| APPL NO | 17/578779 |
| CURRENT CPC | Vehicle Wheels; Castors; Axles for Wheels or Castors; Increasing Wheel Adhesion B60B 19/003 (20130101) Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 53/12 (20190201) Apparatus for Enzymology or Microbiology; C12M 23/44 (20130101) C12M 23/50 (20130101) C12M 23/52 (20130101) C12M 29/10 (20130101) C12M 41/48 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0225 (20130101) Original (OR) Class G05D 1/0291 (20130101) G05D 1/0891 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220230703 | Craddock et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nova Southeastern University (Fort Lauderdale, Florida) |
| ASSIGNEE(S) | Nova Southeastern University (Fort Lauderdale, Florida) |
| INVENTOR(S) | Travis Craddock (Fort Lauderdale, Florida); Gordon Broderick (Fort Lauderdale, Florida) |
| ABSTRACT | Disclosed is mapping complex inflammatory mechanisms in (Gulf War Illness) GWI to improve understanding of the immunologic underpinnings of GWI, the compounding effects of co-morbidity with post-traumatic stress disorder, and the potential of this co-morbidity to define a unique subtype of GWI. Predictive modeling assesses possible changes to putative treatments of GWI in the context of a probable PTSD diagnosis or lack thereof. A logic model is constructed to represent the neuroimmune system across the blood-brain barrier (BBB) connecting the central nervous system to blood-based system. Next, the model results of a GWI cohort are topologically compared with and without PTSD symptoms to mouse models of GWI in blood and use the corresponding neuroimmune states in a mouse brain to infer the blood-brain state of GWI subjects. This inference is then used to guide predictive modeling of treatment courses designed to return the overall neuroimmune system to healthy regulation. |
| FILED | Monday, November 29, 2021 |
| APPL NO | 17/537394 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/20 (20190201) Original (OR) Class G16B 15/30 (20190201) G16B 40/00 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/70 (20180101) G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220230883 | Chowdhury et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Srabanti Chowdhury (San Ramon, California); Dong Ji (San Jose, California) |
| ABSTRACT | In certain examples, methods and semiconductor structures are directed to use of a doped buried region (e.g., Mg-dopant) including a III-Nitride material and having a diffusion path (“ion diffusion path”) that includes hydrogen introduced by using ion implantation via at least one ion species. An ion implantation thermal treatment causes hydrogen to diffuse through the ion implanted path and causes activation of the buried region. In more specific examples in which such semiconductor structures have an ohmic contact region at which a source of a transistor interfaces with the buried region, the ohmic contact region is without etching-based damage due at least in part to the post-ion implantation thermal treatment. |
| FILED | Friday, May 15, 2020 |
| APPL NO | 17/609194 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0254 (20130101) H01L 21/266 (20130101) H01L 21/3245 (20130101) H01L 21/26546 (20130101) Original (OR) Class H01L 29/2003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220231218 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xudong Wang (Middleton, Wisconsin); Fan Yang (Suzhou, China PRC); Jun Li (Madison, Wisconsin) |
| ABSTRACT | A flexible piezoelectric thin film, and method of manufacture, has a polyvinyl alcohol (PVA)-glycine-PVA sandwich heterostructure. The thin film is manufactured by evaporating the solvent from a glycine-PVA mixture solution. The film automatically assembles into the PVA-glycine-PVA sandwich heterostructure as it is salted out. Strong hydrogen bonding between the oxygen atoms in glycine and hydroxyl groups on PVA chains are responsible for the nucleation and growth of the piezoelectric γ-glycine and alignment of the domain orientation. |
| FILED | Thursday, January 21, 2021 |
| APPL NO | 17/154711 |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/18 (20130101) C08J 7/06 (20130101) C08J 2331/04 (20130101) C08J 2371/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 1/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/23 (20130101) H01L 41/0472 (20130101) H01L 41/0805 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20220225882 | ROGERS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John A. ROGERS (Evanston, Illinois); Li GAO (Urbana, Illinois); Viktor MALYARCHUK (Urbana, Illinois); Richard Chad WEBB (Urbana, Illinois) |
| ABSTRACT | Provided are tissue-mounted devices and methods for monitoring a thermal transport property (e.g., thermal conductivity, thermal diffusivity, heat capacity) of tissue, such as skin. The devices conformally mount to the tissue and have one or more thermal actuators and a plurality of sensors. The actuator applies heat to the tissue and the sensors to detect a spatio temporal distribution of a physiological tissue parameter or physical property resulting from the heating. This spatio temporal information may be correlated with a rate, velocity and/or direction of blood flow, the presence of a vascular occlusion, circulation changes due to inflammation, hydration level and other physiological parameters. |
| FILED | Thursday, September 30, 2021 |
| APPL NO | 17/491316 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/002 (20130101) A61B 5/015 (20130101) Original (OR) Class A61B 5/028 (20130101) A61B 5/0048 (20130101) A61B 5/0205 (20130101) A61B 5/0261 (20130101) A61B 5/318 (20210101) A61B 5/369 (20210101) A61B 5/389 (20210101) A61B 5/0537 (20130101) A61B 5/683 (20130101) A61B 5/02007 (20130101) A61B 5/4875 (20130101) A61B 5/6802 (20130101) A61B 5/6824 (20130101) A61B 5/6832 (20130101) A61B 2560/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226362 | LU et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zheng-Rong LU (Cleveland, Ohio); Anthony MALAMAS (Cleveland, Ohio); Maneesh GUJRATI (Cleveland, Ohio); Da SUN (Cleveland, Ohio) |
| ABSTRACT | A compound comprising formula (I): wherein R1 is an akylamino group or a group containing at least one aromatic group; R2 and R3 are independently an aliphatic group or hydrophobic group; R4 and R5 are independently H, a substituted or unsubstituted akyl group, an akenyl group, an acyl group, an aromatic group, polymer, a targeting group, or a detectable moiety; a, b, c, and d are independently an integer from 1 to 10; and pharmaceutically acceptable salts thereof. |
| FILED | Tuesday, September 28, 2021 |
| APPL NO | 17/487562 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Original (OR) Class A61K 48/0033 (20130101) Peptides C07K 5/0606 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2320/31 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226509 | Yap et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michigan Technological University (Houghton, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yoke Khin Yap (Houghton, Michigan); Dongyan Zhang (Houghton, Michigan); Amit Acharya (Houghton, Michigan); Nazmiye Yapici (South Lyon, Michigan); Xiuling Liu (Ann Arbor, Michigan) |
| ABSTRACT | A example compound according to the present disclosure includes, among other possible things, a nanodot carrier, a moiety, and a linker having first and second functional groups, wherein the first functional group is covalently linked to the nanodot carrier, and the second functional group is covalently linked to the moiety. An example method of making a nanodot carrier is also disclosed. |
| FILED | Monday, June 01, 2020 |
| APPL NO | 17/615425 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0071 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/0041 (20130101) Original (OR) Class A61K 49/0058 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Peptides C07K 16/2812 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/533 (20130101) G01N 33/5005 (20130101) G01N 33/54346 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226543 | Yaszemski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota); The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael J. Yaszemski (Rochester, Minnesota); Anthony J. Windebank (Zumbro Falls, Minnesota); Ahad M. Siddiqui (Rochester, Minnesota); James L. Herrick (Rochester, Minnesota); Suzanne L. Glass (Winston Salem, North Carolina); Alan L. Miller, II (Rochester, Minnesota); Brian E. Waletzki (Eyota, Minnesota); Nicolas N. Madigan (Rochester, Minnesota); Jeffrey Schwartz (Princeton, New Jersey); Jean E. Schwarzbauer (Princeton, New Jersey); Kelly S. Lim (Princeton, New Jersey); Stephen B. Bandini (Princeton, New Jersey); Gregory M. Harris (Princeton, New Jersey); Jeffrey W. Chen (Princeton, New Jersey) |
| ABSTRACT | A matrix for neuron regeneration. The matrix can include a sheet having a first surface and a second surface opposite the first surface, the second surface having a plurality of integrally formed ridges. The sheet can have a spiral shape, such that the first surface of the sheet faces the second surface of the sheet. The sheet and the integrally formed ridges can comprise oligo(poly(ethylene glycol) fumarate). |
| FILED | Thursday, April 30, 2020 |
| APPL NO | 17/607245 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) A61K 35/30 (20130101) A61K 38/185 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/06 (20130101) A61L 27/16 (20130101) A61L 27/28 (20130101) A61L 27/047 (20130101) A61L 27/52 (20130101) Original (OR) Class A61L 27/383 (20130101) A61L 27/3834 (20130101) A61L 2430/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226783 | Alexiou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts); The University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ayse Asatekin Alexiou (Arlington, Massachusetts); Samuel John Lounder (Medford, Massachusetts); Jeffrey R. McCutcheon (Tolland, Connecticut); Xin Qian (Storrs, Connecticut); Tulasi Ravindran (Storrs, Connecticut) |
| ABSTRACT | Disclosed are methods for preparing a thin film composite membrane by subjecting a solution comprising one or more zwitterionic copolymers to an electrospraying process, thereby preparing the thin film composite membrane. |
| FILED | Monday, May 11, 2020 |
| APPL NO | 17/610020 |
| CURRENT CPC | Separation B01D 61/145 (20130101) B01D 67/0002 (20130101) Original (OR) Class B01D 69/02 (20130101) B01D 69/122 (20130101) B01D 71/76 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/112 (20170801) B29C 71/02 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 40/20 (20200101) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 218/20 (20200201) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 133/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227003 | Mahoor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dream Face Technologies, LLC (Lone Tree, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mohammad H. Mahoor (Centennial, Colorado); Joshua T. Lane (Englewood, Colorado); Hojjat Abdollahi Pourhaghighi (Denver, Colorado); Eshrat S. Emamian (Lone Tree, Colorado) |
| ABSTRACT | A companion robot is disclosed. In some embodiments, the companion robot may include a head having a facemask and a projector configured to project facial images onto the facemask; a facial camera; a microphone configured to receive audio signals from the environment; a speaker configured to output audio signals; and a processor electrically coupled with the projector, the facial camera, the microphone, and the speaker. In some embodiments, the processor may be configured to receive facial images from the facial camera; receive speech input from the microphone; determine an audio output based on the facial images and/or the speech input; determine a facial projection output based the facial images and/or the speech input; output the audio output via the speaker; and project the facial projection output on the facemask via the projector. |
| FILED | Friday, January 14, 2022 |
| APPL NO | 17/575640 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1697 (20130101) B25J 11/001 (20130101) B25J 11/0015 (20130101) Original (OR) Class B25J 13/003 (20130101) Electric Digital Data Processing G06F 3/0481 (20130101) Image or Video Recognition or Understanding G06V 40/174 (20220101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 25/63 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227624 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dominika Agnieszka BUCHBERGER (Warsaw, Poland); University of Louisville Research Foundation, Inc. (Louisville, Kentucky); Uniwersytet Warszawski (Warsaw, Poland) |
| ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky); Uniwersy tet Warszawski (Warsaw, Poland) |
| INVENTOR(S) | Hui Wang (Louisville, Kentucky); Thad Druffel (Louisville, Kentucky); Dominika Agnieszka Buchberger (Warsaw, Poland) |
| ABSTRACT | Methods for wet chemical synthesis of lithium argyrodites are provided, which in some embodiments include includes dissolving a stoichiometric mixture of precursors in a small quantity of solvent in an argon atmosphere, drying the mixture under vacuum or an inert gas atmosphere to evaporate the solvent, and then annealing to obtain a final lithium argyrodite product. Further embodiments comprise synthesizing the precursors, and excess halide doping to achieve higher ionic conductivity. |
| FILED | Thursday, April 16, 2020 |
| APPL NO | 17/604096 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 17/22 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/82 (20130101) C01P 2002/85 (20130101) C01P 2004/03 (20130101) C01P 2006/40 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0562 (20130101) H01M 2220/20 (20130101) H01M 2300/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227626 | BARSOUM et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michel BARSOUM (Moorestown, New Jersey); Varun NATU (Philadelphia, Pennsylvania) |
| ABSTRACT | Provided are methods of stabilizing MXene compositions using polyanionic salts so as to reduce the oxidation of the MXenes. Also provided are stabilized MXene compositions. |
| FILED | Friday, June 12, 2020 |
| APPL NO | 17/617082 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 21/062 (20130101) C01B 21/076 (20130101) Original (OR) Class C01B 21/0617 (20130101) C01B 21/0637 (20130101) C01B 32/90 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/20 (20130101) C01P 2004/84 (20130101) C01P 2006/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227641 | FAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Donglei FAN (Austin, Texas); Weigu LI (Austin, Texas) |
| ABSTRACT | Disclosed herein are conductive polymer-based composites. The composites include a conductive polymer entangled in a thin substrate. The composites may be hydrophobic or hydrophilic. The hydrophilic composites may be used as solar steamers for water purification, and the hydrophobic composites can be used to sequester hydrophobic materials, such as oil, from watery mixes. |
| FILED | Wednesday, May 20, 2020 |
| APPL NO | 17/612867 |
| CURRENT CPC | Separation B01D 1/0035 (20130101) B01D 5/006 (20130101) B01D 5/009 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/261 (20130101) B01J 20/3085 (20130101) B01J 20/28045 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/14 (20130101) C02F 1/043 (20130101) C02F 1/285 (20130101) C02F 1/288 (20130101) Original (OR) Class C02F 2103/007 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/127 (20130101) H01B 1/128 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227652 | BLANEY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lee BLANEY (Baltimore, Maryland); Utsav SHASHVATT (Baltimore, Maryland); Charles PORTNER (Baltimore, Maryland) |
| ABSTRACT | Separation methods and systems for converting high concentrations of animal wastes and other nutrient-rich organic materials into nutrients and other useful products such as struvite and potassium struvite. Advantageously, the system and methods do not require the addition of external chemicals other than an acid and a base. |
| FILED | Monday, April 04, 2022 |
| APPL NO | 17/712455 |
| CURRENT CPC | Separation B01D 33/03 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 8/005 (20130101) B01J 10/002 (20130101) B01J 19/18 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/20 (20130101) C02F 1/5209 (20130101) C02F 1/5236 (20130101) C02F 1/5281 (20130101) C02F 11/121 (20130101) Original (OR) Class C02F 2101/105 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227677 | Mehdipour et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Iman Mehdipour (Los Angeles, California); Raghubir Gupta (Cary, North Carolina); Gabriel D. Falzone (Los Angeles, California); Gaurav N. Sant (Los Angeles, California); Dante Simonetti (Los Angeles, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Iman Mehdipour (Los Angeles, California); Raghubir Gupta (Cary, North Carolina); Gabriel D. Falzone (Los Angeles, California); Gaurav N. Sant (Los Angeles, California); Dante Simonetti (Los Angeles, California) |
| ABSTRACT | Provided herein are systems for carbonation curing and CO2 mineralization of concrete composites and methods of manufacturing a carbonated concrete composite. A method of manufacturing a carbonated concrete composites includes contacting concrete with CO2-containing gas streams in the carbonation reactor having a gas stream inlet and an outlet to provide optimal gas flow distribution and gas velocity. The concrete precursor includes a binder, one or more aggregates, and water. A gas stream is received at the carbonation reactor. The gas stream includes carbon dioxide. The concrete precursor is maintained at a suitable temperature in the carbonation reactor to thereby react the concrete precursor with the gas stream to produce carbonate minerals in the carbonated concrete composite. |
| FILED | Monday, January 10, 2022 |
| APPL NO | 17/572448 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0013 (20130101) B01J 19/14 (20130101) B01J 19/26 (20130101) B01J 2219/00029 (20130101) B01J 2219/00155 (20130101) B01J 2219/00166 (20130101) B01J 2219/00243 (20130101) Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 11/245 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 14/06 (20130101) C04B 40/0231 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227783 | Elder et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Taoyuan City, Taiwan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Delwin Elder (Seattle, Washington); Lewis Johnson (Seattle, Washington); Bruce Robinson (Seattle, Washington); Huajun Xu (Seattle, Washington) |
| ABSTRACT | Chromophores with large hyperpolarizabilities, films with electro-optic activity comprising the chromophores, and electro-optic devices comprising the chromophores are disclosed. |
| FILED | Monday, April 04, 2022 |
| APPL NO | 17/713055 |
| CURRENT CPC | Heterocyclic Compounds C07D 307/28 (20130101) C07D 495/04 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/0812 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0058 (20130101) H01L 51/0061 (20130101) H01L 51/0065 (20130101) H01L 51/0068 (20130101) H01L 51/0074 (20130101) H01L 51/0094 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227814 | TAL-GAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, REN (Reno, Nevada); The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yftah TAL-GAN (Reno, Nevada); Gee W. LAU (Urbana, Illinois); Yifang YANG (Reno, Nevada) |
| ABSTRACT | Disclosed herein are compositions, methods of treatment and kits for treating Streptococcus Pneumoniae infections. In some examples, compositions including cyclic dominant negative competence stimulating peptide analogs are disclosed and used for treating Streptococcus Pneumoniae infections. |
| FILED | Thursday, May 21, 2020 |
| APPL NO | 17/613272 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 45/06 (20130101) Peptides C07K 7/64 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227940 | Mei et al. |
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| FUNDED BY |
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| APPLICANT(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| ASSIGNEE(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| INVENTOR(S) | Jianguo Mei (West Lafayette, Indiana); Christopher Uyeda (Lafayette, Indiana); John Andjaba (Somerville, Massachusetts); Christopher Rybak (Wheaton, Illinois) |
| ABSTRACT | A conjugated azopolymer and methods for making same. The azopolymer includes a plurality of monomer units containing isoindigo with R1 and R2 substituent groups, wherein R1 can be one or more C1 to 30 hydrocarbons; and R2 can be H or F. The azopolymer can have a number average molecular weight (Mn) of 4 to 20 kDa; a weight average molecular weight (Mw) of 12 to 50 kDa; and a poly dispersity index (PDI) of 2 to 3. The polymer can further have selected maximal wavelengths (λmax) of 481 to 709 nm and electrochemical reduction events of −0.4 to −1.0 V against an Ag/AgCl reference electrode. |
| FILED | Wednesday, January 19, 2022 |
| APPL NO | 17/579315 |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/0672 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220228035 | HAN et al. |
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| FUNDED BY |
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| APPLICANT(S) | BRANDEIS UNIVERSITY (Waltham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Grace G.D. HAN (Waltham, Massachusetts); Mihael A. GERKMAN (Waltham, Massachusetts) |
| ABSTRACT | The invention relates to a device that includes a substrate and a thin film of a photo-switchable adhesive layer applied to at least one surface of the substrate. A method of releasably supporting a product that includes adhering a product onto the thin film of the device and exposing the thin film to light sufficient to cause a change in the adhesive strength of the thin film. A method of making the device is also disclosed. |
| FILED | Monday, May 04, 2020 |
| APPL NO | 17/608594 |
| CURRENT CPC | Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 7/40 (20180101) C09J 7/381 (20180101) Original (OR) Class C09J 139/00 (20130101) C09J 2203/326 (20130101) C09J 2301/408 (20200801) C09J 2301/416 (20200801) C09J 2301/502 (20200801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220228158 | Genung |
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| FUNDED BY |
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| APPLICANT(S) | Stony Creek Colors, Inc. (Springfield, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shawn Genung (Springfield, Tennessee) |
| ABSTRACT | According to the invention, there is provided a novel population of indigo plants (Indigofera suffruticosa) producing a higher than average level of indican. This invention thus relates to an assemblage of indigo seeds of the population, to the indigo plants of population, and to methods for producing indigo varieties with high indican content derived from the indigo plants of the population. |
| FILED | Wednesday, January 19, 2022 |
| APPL NO | 17/578807 |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 1/02 (20130101) A01H 1/04 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 36/48 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/825 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220228911 | Muller et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andreas Muller (Tampa, Florida); Juan Sebastian Gomez Velez (Tampa, Florida) |
| ABSTRACT | A method for enhancement of spontaneous Raman scattering (SRS) from gases comprising a multimode blue laser diode which receives feedback from a near concentric bidirectional multipass cavity in such a way as to generate a circulating power of order 100 W for a sample volume of 10 mm3. The feedback, provided via a volume Bragg grating, reduces the laser bandwidth to 4 cm−1. Spectra of spontaneous Raman scattering from ambient atmospheric air, detected collinearly with the pump, were recorded with a limit of detection below 1 part-per-million. |
| FILED | Monday, April 04, 2022 |
| APPL NO | 17/712679 |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/18 (20130101) G01J 3/021 (20130101) G01J 3/0208 (20130101) G01J 3/4412 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/0009 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/32341 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220228965 | Sulchek et al. |
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| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Todd Sulchek (Atlanta, Georgia); Alexander Alexeev (Atlanta, Georgia); Bushra Tasadduq (Atlanta, Georgia) |
| ABSTRACT | A microchannel for processing cells by compression of the cells including an inlet, ridges and an outlet. Each ridge including a compressive surface and a cell adhesion entity. The outlet configured to remove at least one of a first portion of the cells and a second portion of the cells from the microchannel. Each ridge oriented at an angle of from 25 degrees to 70 degrees relative to a center axis of the microchannel. The cell adhesion entity configured such that the first portion of the cells has a first adhesion property relative to the cell adhesion entity to follow a first trajectory through the microchannel. The cell adhesion entity further configured such that the second portion of the cells has a second adhesion property relative to the cell adhesion entity to follow a second trajectory through the microchannel. The first trajectory is different from the second trajectory. |
| FILED | Friday, February 04, 2022 |
| APPL NO | 17/650033 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 3/502776 (20130101) B01L 2200/0652 (20130101) B01L 2200/0668 (20130101) B01L 2300/16 (20130101) B01L 2300/0877 (20130101) B01L 2400/086 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/34 (20130101) G01N 15/1056 (20130101) Original (OR) Class G01N 33/5005 (20130101) G01N 2015/1006 (20130101) G01N 2015/1081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220228992 | GAN et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Buffalo, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Qiaoqiang GAN (East Amherst, New York); Nan ZHANG (Buffalo, New York); Haomin SONG (Williamsville, New York) |
| ABSTRACT | Structures and methods for Surface-Enhanced Raman Spectroscopy (SERS) are presented. In some embodiments, a SERS structure includes a ground plate with a spacer layer disposed thereon. A first plurality of metallic nanostructures is disposed on the spacer layer such that a portion of the spacer layer is exposed in gaps formed between the nanostructures of the first plurality of metallic nanostructures. In some embodiments, a first metallic layer is annealed to form the first plurality of metallic nanostructures. A second plurality of metallic nanostructures is disposed on the spacer layer in the gaps of the first plurality of metallic nanostructures. In some embodiments, a second metallic layer is annealed to form the second plurality of metallic nanostructures. |
| FILED | Wednesday, May 06, 2020 |
| APPL NO | 17/609454 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/554 (20130101) G01N 21/658 (20130101) Original (OR) Class G01N 2021/655 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220229048 | Yap et al. |
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| FUNDED BY |
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| APPLICANT(S) | Michigan Technological University (Houghton, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yoke Khin Yap (Houghton, Michigan); Dongyan Zhang (Houghton, Michigan); Rodney Oakley (Hancock, Michigan); Nazmiye Yapici (South Lyon, Michigan); Xiuling Liu (Ann Arbor, Michigan) |
| ABSTRACT | An example compound according to an example of the present disclosure includes, among other possible things, a nanotube carrier, a moiety, a linker having first and second functional groups, wherein the first functional group is covalently linked to the nanotube carrier, and the second functional group is covalently linked to the moiety. An example method of making a nanotube compound according to the present disclosure is also disclosed. |
| FILED | Monday, June 01, 2020 |
| APPL NO | 17/615441 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 35/146 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/533 (20130101) Original (OR) Class G01N 33/582 (20130101) G01N 33/587 (20130101) G01N 33/54346 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220229224 | Rechtsman et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE PENN STATE RESEARCH FOUNDATON (University Park, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mikael Caleb Rechtsman (Boalsburg, Pennsylvania); Jonathan Guglielmon (State College, Pennsylvania); Kevin Peng Chen (University Park, Pennsylvania) |
| ABSTRACT | Embodiments relate to generating a configuration of waveguide propagation constants formed in a waveguide array system. The configuration of propagation constants can be made via a recursive detuning process that produces approximations to a fractal structure designed to maximally localize eigenstates of a waveguide array. The eigenstates being maximally localized enables strong suppression of crosstalk between the waveguides. Performing more detuning iterations can produce a configuration of propagation constants that better approximates the fractal structure and suppresses crosstalk over larger distances. |
| FILED | Friday, June 26, 2020 |
| APPL NO | 17/595748 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/02042 (20130101) Original (OR) Class G02B 27/0012 (20130101) Transmission H04B 10/2507 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220229406 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Fei Wang (Knoxville, Tennessee); Jingxin Wang (Knoxville, Tennessee); Yiwei Ma (Knoxville, Tennessee) |
| ABSTRACT | A transformer emulator includes a DC bus, a first power electronics converter circuit having a DC port coupled to the DC bus, a second power electronics converter circuit having a DC port coupled to the DC bus, and a third power electronics converter circuit having DC port coupled to the DC bus. The transformer emulator further includes a control circuit configured to control the first, second and third power electronics converter circuits to emulate a transformer having a first port corresponding to an AC port of the first power electronics converter circuit and a second port corresponding to an AC port of the second power electronics converter circuit. The control circuit is configured to control the first and second power electronics converter circuits to emulate a voltage transformation of the transformer and to control the third power electronics converter circuit to emulate a loss of the transformer. |
| FILED | Friday, January 15, 2021 |
| APPL NO | 17/150567 |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/041 (20130101) G05B 17/02 (20130101) Original (OR) Class Electric Digital Data Processing G06F 30/20 (20200101) G06F 30/367 (20200101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 2203/20 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220229441 | Reiserer et al. |
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| FUNDED BY |
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| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ronald S. Reiserer (Nashville, Tennessee); John P. Wikswo (Brentwood, Tennessee) |
| ABSTRACT | A robot for transporting a biodevice from one place to another place, comprising a body for carrying the biodevice; a driving assembly for driving the body in omnidirectional motion; a sensing unit for sensing at least a position and orientation of the body; and a control unit coupled to the driving assembly and the sensing unit for generating one or more control signals based on at least the sensed position and orientation of the body to drive the driving assembly so as to move the body to a desired place and to arrive with the correct orientation. |
| FILED | Wednesday, January 19, 2022 |
| APPL NO | 17/578779 |
| CURRENT CPC | Vehicle Wheels; Castors; Axles for Wheels or Castors; Increasing Wheel Adhesion B60B 19/003 (20130101) Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 53/12 (20190201) Apparatus for Enzymology or Microbiology; C12M 23/44 (20130101) C12M 23/50 (20130101) C12M 23/52 (20130101) C12M 29/10 (20130101) C12M 41/48 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0225 (20130101) Original (OR) Class G05D 1/0291 (20130101) G05D 1/0891 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220230422 | Shen et al. |
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| FUNDED BY |
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| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xipeng Shen (Raleigh, North Carolina); Lin Ning (Raleigh, North Carolina) |
| ABSTRACT | An exemplary clustering and computation reuse method comprises providing an artificial convolutional neural network; detecting that neuron vectors associated with an input layer and/or a hidden layer of the convolutional neural network are similar to one another; detecting similarities among the neuron vectors associated with the input layer and/or the at least one hidden layer during execution of a computer program; clustering similar neuron vectors into groups; computing a centroid vector for each group; performing, by a computer processor, computations using the centroid vector associated with one of the groups as a representative for one of the members of the group to generate an output for the computation, wherein the output is generated during execution of the computer program; and reusing, by the computer processor, the output for the computation involving the centroid vector for another computation involving another member of the group. |
| FILED | Wednesday, June 17, 2020 |
| APPL NO | 17/617438 |
| CURRENT CPC | Image or Video Recognition or Understanding G06V 10/82 (20220101) G06V 10/763 (20220101) G06V 10/7747 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220230669 | Buchanan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kristen Buchanan (Bellvue, Colorado); Xiao Wang (Homer Glen, Illinois); Xuemei Cheng (Wynnewood, Pennsylvania) |
| ABSTRACT | A topological spin memory effect, defined as the recovery of magnetic skyrmions or magnetic bubble skyrmions in magnetic thin films after a transition to a dramatically different spin texture, is used for encrypted non-volatile information storage. The storage strategy is based on magnetic skyrmions, that is, topologically protected spin textures comprising chiral domain walls surrounding small (e.g., nanometers to microns in diameter), typically circular, single-domain cores. Systems and methods are described for encrypted non-volatile information storage based on a spin memory effect in magnetic thin films that support skyrmions. Systems and methods encrypt and recover information stored in the form of magnetic skyrmions. |
| FILED | Wednesday, January 19, 2022 |
| APPL NO | 17/579048 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/78 (20130101) Static Stores G11C 11/161 (20130101) Original (OR) Class Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 10/3268 (20130101) H01F 10/3286 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/02 (20130101) H01L 43/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220230773 | Watkins et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | James Watkins (South Hadley, Massachusetts); Michael R. Beaulieu (Chicopee, Massachusetts); Nicholas R. Hendricks (South Deerfield, Massachusetts) |
| ABSTRACT | Aspects relate to patterned nanostructures having a feature size not including film thickness of below 5 microns. The patterned nanostructures are made up of nanoparticles having an average particle size of less than 100 nm. A nanoparticle composition, which, in some cases, includes a binder, is applied to a substrate. A patterned mold used in concert with electromagnetic radiation function to manipulate the nanoparticle composition in forming the patterned nanostructure. In some embodiments, the patterned mold nanoimprints a pattern onto the nanoparticle composition and the composition is cured through UV or thermal energy. Three-dimensional patterned nanostructures may be formed. A number of patterned nanostructure layers may be prepared and joined together. In some cases, a patterned nanostructure may be formed as a layer that is releasable from the substrate upon which it is initially formed. Such releasable layers may be arranged to form a three-dimensional patterned nanostructure for suitable applications. |
| FILED | Thursday, April 07, 2022 |
| APPL NO | 17/715411 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Optical Elements, Systems, or Apparatus G02B 1/118 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/08 (20130101) Original (OR) Class H01B 3/10 (20130101) H01B 13/003 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0015 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/04 (20130101) H01M 6/40 (20130101) H01M 8/124 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220230866 | JARROLD et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF INDIANA UNIVERSITY (Indianapolis, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Martin F. JARROLD (Bloomington, Indiana); Benjamin E. DRAPER (Bloomington, Indiana) |
| ABSTRACT | A charge detection mass spectrometer may include an electrostatic linear ion trap (ELIT) or orbitrap, a source of ions to supply ions to the ELIT or orbitrap, a processor operatively coupled to the ELIT or orbitrap, a display monitor coupled to the processor, and a memory having instructions stored therein executable by the processor to produce a control graphic user interface (GUI) on the display monitor, the control GUI including at least one selectable GUI element for at least one corresponding operating parameter of the ELIT or orbitrap, receive a first user command, via user interaction with the control GUI, corresponding to selection of the at least one selectable GUI element, and control the ELIT or orbitrap to control the at least one corresponding operating parameter of the ELIT or orbitrap in response to receipt of, and based on, the first user command. |
| FILED | Friday, April 01, 2022 |
| APPL NO | 17/711126 |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/025 (20130101) H01J 49/0031 (20130101) H01J 49/0036 (20130101) H01J 49/425 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220231171 | Seebauer |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Edmund G. Seebauer (Urbana, Illinois) |
| ABSTRACT | A method of controlling oxygen vacancy concentration in a semiconducting metal oxide includes exposing a treated surface of a crystalline metal oxide to water at a temperature and pressure sufficient to maintain the water in a liquid phase. During the exposure, a portion of the water is adsorbed onto the treated surface and dissociates into atomic oxygen and hydrogen. The atomic oxygen is injected into and diffuses through the crystalline metal oxide, forming isolated oxygen interstitials and oxygen defect complexes. The isolated oxygen interstitials replace oxygen vacancies in the crystalline metal oxide. |
| FILED | Monday, January 10, 2022 |
| APPL NO | 17/571858 |
| CURRENT CPC | Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 1/30 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/32134 (20130101) H01L 21/67075 (20130101) H01L 27/1225 (20130101) H01L 29/7869 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220231202 | Cheng et al. |
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| FUNDED BY |
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| APPLICANT(S) | Oregon State University (Corvallis, Oregon) |
| ASSIGNEE(S) | Oregon State University (Corvallis, Oregon) |
| INVENTOR(S) | Li-Jing Cheng (Corvallis, Oregon); Ye Liu (Corvallis, Oregon) |
| ABSTRACT | Disclosed herein are materials and a micro-LED display with carbon-based light-emitting materials, carbon quantum dots, that are made by a solvothermal synthesis of a mixture of aromatic amino acid, 3,4-dihydroxy-L-phenylalanine (LDOPA), and urea in dimethylformamide (DMF). The mixture is heated in a sealed pressure reactor at a temperature, ranging from 120 degrees Celsius to 350 degrees Celsius, for 4-24 hours. The product is then purified to collect the solid powder. The purified CDs can be dissolved in an acrylate monomer solution or a polymer solution for material delivery and curing process on a target substrate for the applications, including light-emitting devices or sensors. |
| FILED | Wednesday, January 19, 2022 |
| APPL NO | 17/648419 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/166 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/64 (20130101) C01P 2006/60 (20130101) C01P 2006/80 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/65 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 25/0753 (20130101) H01L 33/502 (20130101) Original (OR) Class H01L 2933/0041 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220231485 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Fei Wang (Knoxville, Tennessee); Jingxin Wang (Knoxville, Tennessee); Yiwei Ma (Knoxville, Tennessee) |
| ABSTRACT | An electric power system emulator apparatus includes a plurality of nodes arrayed in first and second dimensions and a plurality of transmission path emulator circuits, respective ones of which are configured to be connected between adjacent ones of the nodes in the first and second dimensions. The apparatus further includes a control circuit configured to control the transmission path emulator circuits to emulate transmission paths of an electric power system. The control circuit may be configured to control the transmission path emulator circuits to emulate transmission lines and/or transformers. The transmission path emulator circuits may include respective power electronics converter circuits. The apparatus may further include source/load emulator circuits configured to be coupled to the nodes. |
| FILED | Friday, January 15, 2021 |
| APPL NO | 17/150650 |
| CURRENT CPC | Boards, Substations, or Switching Arrangements for the Supply or Distribution of Electric Power H02B 1/20 (20130101) Original (OR) Class H02B 1/30 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20220225892 | Myers et al. |
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| FUNDED BY |
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| APPLICANT(S) | Vivonics, Inc. (Bedford, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ryan Myers (North Andover, Massachusetts); Kristian DiMatteo (Waltham, Massachusetts); Michaelina Dupnik (Brighton, Massachusetts) |
| ABSTRACT | A system for detecting and/or monitoring at least one of pneumothorax, hemopneumothorax, or hemothorax using one or more light sources and one or more light detectors. The system includes one or more light sources adapted to be placed on skin of a living subject. The one or more light detectors are adapted to be placed on the skin of the living subject. A processing subsystem is coupled to the one or more light sources and the one or more light detectors detects and/or monitors the presence of at least one of pneumothorax, hemopneumothorax, or hemothorax in the living subject. |
| FILED | Tuesday, January 18, 2022 |
| APPL NO | 17/577659 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/72 (20130101) A61B 5/0073 (20130101) A61B 5/0075 (20130101) A61B 5/0816 (20130101) Original (OR) Class A61B 5/02405 (20130101) A61B 5/6833 (20130101) A61B 5/14542 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226159 | LEUNG |
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| FUNDED BY |
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| APPLICANT(S) | THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE ARMY (Fort Detrick, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kai P. LEUNG (San Antonio, Texas) |
| ABSTRACT | A layered composite for scar treatment and prevention, the layered composite including a backing section; a drug matrix section; and a skin-interfacing section. The drug matrix section may be disposed between the back section and the skin-interfacing section. The drug matrix section may include pirfenidone in an amount of from about 1 to about 20 mg/cm2. The layered composite may provide greater than about 75% release of the pirfenidone over a period of about 48 to 72 hours. A method for scar treatment and prevention that includes applying a layered composite as described to a burn wound. |
| FILED | Monday, January 31, 2022 |
| APPL NO | 17/588950 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 13/00063 (20130101) Original (OR) Class A61F 13/0253 (20130101) A61F 13/0263 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/4418 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226653 | Carlson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew L. Carlson (Rochester, Minnesota) |
| ABSTRACT | Electrical stimulation devices can be used to treat tinnitus. For example, tinnitus can be treated using implantable electrodes and stimulation devices for delivering electrical stimulation to a patient's cochlear region, such as the cochlear promontory. Intraosseous cochlear promontory electrode(s), endosteal electrode(s), subendosteal electrode(s), or short intracochlear electrode(s) (or a combination thereof), connected to a cochlear implant receiver/stimulator device, can provide a successful model for long-term treatment of tinnitus in a large number of patients. In some cases, patients can simply turn on the tinnitus implant when experiencing troublesome tinnitus and gain instant relief. |
| FILED | Friday, May 01, 2020 |
| APPL NO | 17/609160 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0541 (20130101) A61N 1/36038 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226901 | Sparks |
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| FUNDED BY |
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| APPLICANT(S) | Product Innovation and Engineering L.L.C. (Saint James, Missouri) |
| ASSIGNEE(S) | Product Innovation and Engineering L.L.C. (Saint James, Missouri) |
| INVENTOR(S) | Todd Eugene Sparks (Rolla, Missouri) |
| ABSTRACT | A laser power control method for additive manufacturing includes a pre-processing component and an intra-processing component. The pre-processing component creates in the system controller a machine code expressed additive-path-with-geometry-metadata that includes a path description. The path description represents the path of the beam source on the build and includes a geometry index for the build. The intra-processing component calculates required power for the beam at intervals and events on the beam path based upon the additive-path-with-geometry-metadata and calculations of the energy balance at the melt pool and the total energy for each point P(s) on the path. |
| FILED | Wednesday, January 20, 2021 |
| APPL NO | 17/153650 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/85 (20210101) B22F 10/366 (20210101) Original (OR) Class B22F 10/368 (20210101) B22F 12/30 (20210101) B22F 12/44 (20210101) B22F 12/50 (20210101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) B33Y 50/02 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220226994 | Gombolay et al. |
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| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew C. Gombolay (Altanta, Georgia); Zheyuan Wang (Atlanta, Georgia) |
| ABSTRACT | An exemplary scheduler system and method are disclosed that can schedule a plurality of heterogenous robots to perform a set of tasks using heterogeneous graph attention network models. The exemplary scheduler system and method can outperform other work in multi-robot scheduling both in terms of schedule optimality and the total number of feasible schedules found and also in a scalable framework that can be trained via imitation-based Q-learning operations. The exemplary scheduler system and method can autonomously learn scheduling policies on multiple application domains. |
| FILED | Tuesday, July 20, 2021 |
| APPL NO | 17/380132 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1656 (20130101) Original (OR) Class Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 2219/32335 (20130101) G05B 2219/39001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227486 | Acee et al. |
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| FUNDED BY |
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| APPLICANT(S) | Textron Innovations Inc. (Providence, Rhode Island) |
| ASSIGNEE(S) | Textron Innovations Inc. (Providence, Rhode Island) |
| INVENTOR(S) | Aaron Alexander Acee (Flower Mound, Texas); Andrew Thomas Carter (Richland Hills, Texas); Michael Scott Seifert (Southlake, Texas); Shahryar Fotovati (North Richland Hills, Texas) |
| ABSTRACT | A rotor system for a rotorcraft includes a rotor hub having a plurality of blade grips coupled thereto. Each blade grip has a rotor blade coupled thereto. A fairing is disposed at least partially around the rotor hub. Each of a plurality of lead-lag dampers is coupled to at least a respective one of the blade grips. Each lead-lag damper has a damper heat exchanger and a fluid pump operably associated therewith. A fairing heat exchanger is in fluid communication with the damper heat exchangers and the fluid pumps. Each lead-lag damper is configured to drive the respective fluid pump responsive to damping operations to pump a cooling fluid from the respective damper heat exchanger to the fairing heat exchanger. |
| FILED | Thursday, January 21, 2021 |
| APPL NO | 17/154650 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/51 (20130101) Original (OR) Class Springs; Shock-absorbers; Means for Damping Vibration F16F 9/42 (20130101) F16F 13/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227675 | Hunt et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Govermment of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Hunt (Alexandria, Virginia); Guillermo R. Villalobos (Springfield, Virginia); Benjamin Rock (Rockville, Maryland); Shyam S. Bayya (Ashburn, Virginia); Woohong Kim (Washington, District of Columbia); Ishwar D. Aggarwal (Waxhaw, North Carolina); Bryan Sadowski (Falls Church, Virginia); Jasbinder S. Sanghera (Ashburn, Virginia) |
| ABSTRACT | The present invention provides a method for making a high strength, small grain size ceramic having a transgranular fracture mode by rapid densification of a green body and subsequent cooling of the densified ceramic. The ceramic may include dislocations, defects, dopants, and/or secondary phases that are formed as a result of the process and resulting in stress fields capable of redirecting or arresting cracks within the material. This ceramic can maintain transparency from ultraviolet to mid-wave infrared. |
| FILED | Friday, April 08, 2022 |
| APPL NO | 17/716085 |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/50 (20130101) C04B 35/64 (20130101) C04B 35/443 (20130101) C04B 35/505 (20130101) Original (OR) Class C04B 35/638 (20130101) C04B 35/4682 (20130101) C04B 2235/77 (20130101) C04B 2235/604 (20130101) C04B 2235/608 (20130101) C04B 2235/667 (20130101) C04B 2235/786 (20130101) C04B 2235/3208 (20130101) C04B 2235/3215 (20130101) C04B 2235/3222 (20130101) C04B 2235/3224 (20130101) C04B 2235/3225 (20130101) C04B 2235/3236 (20130101) C04B 2235/5409 (20130101) C04B 2235/5445 (20130101) C04B 2235/6025 (20130101) C04B 2235/6027 (20130101) C04B 2235/6562 (20130101) C04B 2235/6567 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227783 | Elder et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington (Taoyuan City, Taiwan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Delwin Elder (Seattle, Washington); Lewis Johnson (Seattle, Washington); Bruce Robinson (Seattle, Washington); Huajun Xu (Seattle, Washington) |
| ABSTRACT | Chromophores with large hyperpolarizabilities, films with electro-optic activity comprising the chromophores, and electro-optic devices comprising the chromophores are disclosed. |
| FILED | Monday, April 04, 2022 |
| APPL NO | 17/713055 |
| CURRENT CPC | Heterocyclic Compounds C07D 307/28 (20130101) C07D 495/04 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/0812 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0058 (20130101) H01L 51/0061 (20130101) H01L 51/0065 (20130101) H01L 51/0068 (20130101) H01L 51/0074 (20130101) H01L 51/0094 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220228061 | Boyd et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Darryl A. Boyd (Alexandria, Virginia); Michael H. Stewart (Springfield, Virginia); Kimihiro Susumu (Alexandria, Virginia); Eunkeu Oh (Alexandria, Virginia); James P. Wissman (Hyattsville, Maryland) |
| ABSTRACT | This disclosure concerns a method of making a ligand for Quantum Dot functionalization, a method of making a functionalized Quantum Dot (QD) with a ligand, and a method of making a transparent luminescent quantum dot thiol-yne nanocomposite with tailorable optical, thermal, and mechanical properties. The prepolymer solution and functionalized Quantum Dot can be used in additive manufacturing. |
| FILED | Tuesday, April 05, 2022 |
| APPL NO | 17/713983 |
| CURRENT CPC | Heterocyclic Compounds C07D 339/04 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/02 (20130101) C09K 11/886 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220228204 | LAPOINTE et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (Montreal, Canada) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jacques LAPOINTE (Lasalle, Canada); Yogesh M. BRAMHECHA (Halifax, Canada) |
| ABSTRACT | Methods and kits are provided for assessing the cancer risk of a subject having prostate cancer by detecting DNA copy number alterations. In particular, 16p13.3 gain, and further in addition PTEN deletion are assessed, and detected using probes such as FISH probes to provide a customized treatment options to the screened individual. |
| FILED | Monday, February 07, 2022 |
| APPL NO | 17/666134 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6841 (20130101) Original (OR) Class C12Q 1/6886 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220228811 | Bozorgi et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Payam Bozorgi (Santa Barbara, California); Carl D. Meinhart (Santa Barbara, California); Marin Sigurdson (Goleta, California); Noel C. MacDonald (Santa Barbara, California); David Bothman (Santa Barbara, California); Yu-Wei Liu (Goleta, California) |
| ABSTRACT | Titanium-based thermal ground planes are described. A thermal ground plane in accordance with the present invention comprises a titanium substrate comprising a plurality of channels, wherein the channels are oxidized to form nanostructured titania (NST) coated on the surfaces of the channels, and a vapor cavity, in communication with the plurality of titanium channels, for transporting thermal energy from one region of the thermal ground plane to another region of the thermal ground plane |
| FILED | Monday, November 26, 2012 |
| APPL NO | 13/685579 |
| CURRENT CPC | Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 15/26 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
20220228828 — FIREARM WITH FIELD-REPLACEABLE BLANK-FIRE CHAMBER PREVENTING CHAMBERING OF LIVE ROUNDS
| US 20220228828 | Engel, IV et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Textron Systems Corporation (Hunt Valley, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | William Henry Engel, IV (Cockeysville, Maryland); David Timothy Horst (Bel Air, Maryland) |
| ABSTRACT | A firearm for firing case-telescoped (CT) rounds includes a barrel configured for transit of a bullet of a live CT cartridge in a live-fire operating mode. The live CT cartridge is chambered and fired from a live-fire chamber installed in the live-fire operating mode. The firearm further includes a blank-fire chamber configured to chamber and fire a blank CT cartridge in a blank-fire operating mode, wherein the blank-fire chamber has a second diameter less than a first diameter of the live-fire chamber, to prevent chambering of the live CT cartridge in the blank-fire operating mode. The arrangement can enhance safety by preventing accidental firing of a live round during operation when it is assumed that only blanks are being fired. |
| FILED | Friday, January 15, 2021 |
| APPL NO | 17/150218 |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 11/02 (20130101) Original (OR) Class F41A 21/26 (20130101) F41A 21/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220228919 | Morris et al. |
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| FUNDED BY |
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| APPLICANT(S) | Science Applications International Corporation (Reston, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David M. Morris (Bloomington, Indiana); John P. Timler (River Ridge, Louisiana) |
| ABSTRACT | Infrared transparent constructs (e.g., infrared transparent windows) may be shaped as a dome (e.g., for an infrared detector system) and/or other desired geometries, such as portions of IR seeker domes. Electrically conductive tracing(s) may be printed in desired shapes and forms, e.g., in the form of EMI shielding, an FSS grid, an anti-static component, electrical connectors, etc., and integrated into the interior of the construct structure. The electrically conductive tracing(s) may be printed between layers of independent infrared transparent window components that are then engaged together to form a window preform. Additionally or alternatively, the electrically conductive tracing(s) may be printed between printed layers of infrared transparent ceramic or plastic material built up to form the window preform. Once formed, the window preform may be sintered, e.g., in an ultrafast high temperature sintering process (and optionally further treated) to produce the final infrared transparent construct. |
| FILED | Friday, January 15, 2021 |
| APPL NO | 17/150015 |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/0875 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220229228 | COOLBAUGH et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for the State University of New York (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for the State University of New York (Albany, New York) |
| INVENTOR(S) | Douglas COOLBAUGH (Albany, New York); Gerald LEAKE (Albany, New York) |
| ABSTRACT | There is set forth herein a method including fabricating a photonics structure having one or more photonics device. The method can include forming one or more conductive material formation for communicating electrical signals to and/or from the one or more photonics device. |
| FILED | Thursday, April 16, 2020 |
| APPL NO | 17/596775 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/136 (20130101) G02B 6/12004 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220229663 | Martínez et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | José F. Martínez (Ithaca, New York); Helena Caminal (Ithaca, New York); Kailin Yang (Ithaca, New York); Khalid Al-Hawaj (Ithaca, New York); Christopher Batten (Ithaca, New York) |
| ABSTRACT | A content-addressable processing engine, also referred to herein as CAPE, is provided. Processing-in-memory (PIM) architectures attempt to overcome the von Neumann bottleneck by combining computation and storage logic into a single component. CAPE provides a general-purpose PIM microarchitecture that provides acceleration of vector operations while being programmable with standard reduced instruction set computing (RISC) instructions, such as RISC-V instructions with standard vector extensions. CAPE can be implemented as a standalone core that specializes in associative computing, and that can be integrated in a tiled multicore chip alongside other types of compute engines. Certain embodiments of CAPE achieve average speedups of 14× (up to 254×) over an area-equivalent out-of-order processor core tile with three levels of caches across a diverse set of representative applications. |
| FILED | Friday, January 15, 2021 |
| APPL NO | 17/149936 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/3001 (20130101) G06F 9/3004 (20130101) G06F 9/30036 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220229677 | Heirman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Wim Heirman (Gent, Belgium); Stijn Eyerman (Evergem, Belgium); Kristof Du Bois (Aalst, Belgium); Ibrahim Hur (Portland, Oregon) |
| ABSTRACT | A distributed simulation system is provided that includes a timing simulator and functional simulator(s) on different computing nodes to simulate a graph processing system. The functional simulators are to simulate execution of a set of instructions on the graph processing system and to send information associated with the simulated set of instructions to the timing simulator over the network. The timing simulator is to determine timing information associated with execution of the sets of instructions sent by the functional simulators and send the timing information to the functional simulators over the network. The timing simulator may determine a global synchronization point for the functional simulators and send the timing information for the sets of instructions to respective functional simulators at the global synchronization point. The functional simulators may stall simulation of further instructions until the timing information for its set of instructions is received from the timing simulator. |
| FILED | Saturday, April 02, 2022 |
| APPL NO | 17/712094 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/52 (20130101) G06F 9/455 (20130101) Original (OR) Class G06F 2209/521 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220229723 | Fryman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Joshua B. Fryman (Corvallis, Oregon); Byoungchan Oh (Portland, Oregon); Jason Howard (Portland, Oregon); Sai Dheeraj Polagani (Hillsboro, Oregon) |
| ABSTRACT | Memory requests are protected by encoding memory requests to include error correction codes. A subset of bits in a memory request are compared to a pre-defined pattern to determine whether the subset of bits matches a pre-defined pattern, where a match indicates that a compression can be applied to the memory request. The error correction code is generated for the memory request and the memory request is encoded to remove the subset of bits, add the error correction code, and add at least one metadata bit to the memory request to generate a protected version of the memory request, where the at least one metadata bit identifies whether the compression was applied to the memory request. |
| FILED | Friday, April 01, 2022 |
| APPL NO | 17/711646 |
| CURRENT CPC | Electric Digital Data Processing G06F 11/1044 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220229795 | Cline et al. |
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| FUNDED BY |
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| APPLICANT(S) | Scott N. Cline (Portland, Oregon); Ivan B. Ganev (Portland, Oregon); Robert S. Pawlowski (Beaverton, Oregon); Jason Howard (Portland, Oregon); Joshua B. Fryman (Corvallis, Oregon) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Scott N. Cline (Portland, Oregon); Ivan B. Ganev (Portland, Oregon); Robert S. Pawlowski (Beaverton, Oregon); Jason Howard (Portland, Oregon); Joshua B. Fryman (Corvallis, Oregon) |
| ABSTRACT | A graph processing core includes a plurality of processing pipelines and an interrupt controller unit. Each processing pipeline executes one or more threads and includes, for each thread, a register indicating a currently executing program counter vector and another register indicating an interrupt or exception handler vector. The interrupt controller unit may receive interrupt or exception notifications from the processing pipelines, determine a handler vector based on the notification and a set of registers of the interrupt controller unit, and transmit the handler vector to the processing pipeline that issued the interrupt or exception notification. Further, the issuing pipeline may receive the handler vector from the interrupt controller unit, write a value in the first register into the second register, write the handler vector into the first register, and invoke an interrupt or exception hander based on the value written into the first register. |
| FILED | Friday, April 01, 2022 |
| APPL NO | 17/711209 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/30101 (20130101) G06F 13/24 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220229912 | Tavabi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona); University of Southern California (Marina del Rey, California) |
| INVENTOR(S) | Nazgol Tavabi (Marina Del Rey, California); Palash Goyal (Los Angeles, California); Kristina Lerman (Los Angeles, California); Mohammed Almukaynizi (Chandler, Arizona); Paulo Shakarian (Chandler, Arizona) |
| ABSTRACT | Various embodiments of a computer-implemented framework for predicting exploitation of software vulnerabilities are disclosed. |
| FILED | Thursday, August 22, 2019 |
| APPL NO | 16/548329 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/577 (20130101) Original (OR) Class G06F 40/279 (20200101) G06F 2221/033 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 51/216 (20220501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220229964 | Markowski et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (, None) |
| INVENTOR(S) | Blerta Bajramaj Markowski (Springfield, Virginia); Brian Carl Hicks (Alexandria, Virginia); David Bonanno (Fairfax Station, Virginia); Freddie Santiago (Fort Washington, Maryland) |
| ABSTRACT | Systems and methods are provided for a turnkey modular printed circuit board enclosure that is generated using a template generator. The template generator accepts a user input comprising an enclosure parameter, based on which a manufacturing file may be generated. The manufacturing file may be provided to a fabricator for fabricating the enclosure or the manufacturing file may be modified in a printed circuit board design environment to incorporate a printed circuit board into the enclosure. The printed circuit board may be a separate printed circuit board that is inserted into the enclosure or it may be embedded in a face of the enclosure. |
| FILED | Friday, January 15, 2021 |
| APPL NO | 17/150622 |
| CURRENT CPC | Electric Digital Data Processing G06F 30/392 (20200101) Original (OR) Class G06F 30/394 (20200101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 3/0005 (20130101) H05K 5/0256 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220230703 | Craddock et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nova Southeastern University (Fort Lauderdale, Florida) |
| ASSIGNEE(S) | Nova Southeastern University (Fort Lauderdale, Florida) |
| INVENTOR(S) | Travis Craddock (Fort Lauderdale, Florida); Gordon Broderick (Fort Lauderdale, Florida) |
| ABSTRACT | Disclosed is mapping complex inflammatory mechanisms in (Gulf War Illness) GWI to improve understanding of the immunologic underpinnings of GWI, the compounding effects of co-morbidity with post-traumatic stress disorder, and the potential of this co-morbidity to define a unique subtype of GWI. Predictive modeling assesses possible changes to putative treatments of GWI in the context of a probable PTSD diagnosis or lack thereof. A logic model is constructed to represent the neuroimmune system across the blood-brain barrier (BBB) connecting the central nervous system to blood-based system. Next, the model results of a GWI cohort are topologically compared with and without PTSD symptoms to mouse models of GWI in blood and use the corresponding neuroimmune states in a mouse brain to infer the blood-brain state of GWI subjects. This inference is then used to guide predictive modeling of treatment courses designed to return the overall neuroimmune system to healthy regulation. |
| FILED | Monday, November 29, 2021 |
| APPL NO | 17/537394 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/20 (20190201) Original (OR) Class G16B 15/30 (20190201) G16B 40/00 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/70 (20180101) G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220230785 | Cummings et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John D. Cummings (Stoneham, Massachusetts); John A. Rokosz (Belmont, Massachusetts); Kyle J. Thompson (Boulder, Colorado); Steven J. Weber (Arlington, Massachusetts) |
| ABSTRACT | A high density wiring system to transmit radio frequency (RF) signals to superconducting qubits disposed within a dilution refrigerator is disclosed. The high density wiring system comprises a plurality of flexible layers, with conductive layers disposed between adjacent pairs of flexible layers. The conductive layers may be constructed using phosphor bronze. The wiring system that is disposed at the lower temperature stages of the dilution refrigerator may be coated with a superconducting material. The wiring system is useful for superconducting quantum computers and cryogenic sensors, as well as cryogenic infrastructure. |
| FILED | Wednesday, January 19, 2022 |
| APPL NO | 17/579047 |
| CURRENT CPC | Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 7/04 (20130101) H01B 12/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220231178 | Meade et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Roy Meade (Boise, Idaho); Karan Mehta (Cambridge, Massachusetts); Efraim Megged (Mata, Israel); Jason Orcutt (Katonah, New York); Milos Popovic (Boulder, Colorado); Rajeev Ram (Arlington, Massachusetts); Jeffrey Shainline (Boulder, Colorado); Zvi Sternberg (Metar, Israel); Vladimir Stojanovic (Berkeley, California); Ofer Tehar-Zahav (Hadera, Israel) |
| ABSTRACT | Method and structural embodiments are described which provide an integrated structure using polysilicon material having different optical properties in different regions of the structure. |
| FILED | Friday, April 01, 2022 |
| APPL NO | 17/711728 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/1443 (20130101) H01L 31/182 (20130101) H01L 31/1804 (20130101) H01L 31/02327 (20130101) Original (OR) Class H01L 31/03682 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/546 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/50 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220231233 | Huang et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jinsong Huang (Chapel Hill, North Carolina); Yuze Lin (Chapel Hill, North Carolina); Shangshang Chen (Chapel Hill, North Carolina) |
| ABSTRACT | The present disclosure is directed to perovskite-based solar cell device structures and compositions comprising one or more near infrared sensitive semiconducting materials. The near infrared sensitive semiconducting materials can extend the photoresponse spectra of the devices to the near infrared region, thereby improving the power conversion efficiency of the solar cell. |
| FILED | Friday, April 17, 2020 |
| APPL NO | 17/604015 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/008 (20130101) H01L 51/0036 (20130101) H01L 51/0067 (20130101) H01L 51/0068 (20130101) H01L 51/0072 (20130101) Original (OR) Class H01L 51/0074 (20130101) H01L 51/0091 (20130101) H01L 51/0092 (20130101) H01L 51/441 (20130101) H01L 51/4213 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220231294 | Barsoum et al. |
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| FUNDED BY |
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| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michel W. Barsoum (Moorestown, New Jersey); Babak Anasori (Norristown, Pennsylvania); Yury Gogotsi (Warminster, Pennsylvania) |
| ABSTRACT | The present disclosure is directed to compositions comprising at least one layer having first and second surfaces, each layer comprising: a substantially two-dimensional array of crystal cells, each crystal cell having an empirical formula of M′2M″nXn+1, such that each X is positioned within an octahedral array of M′ and M″; wherein M′ and M″ each comprise different Group 11113, WE, VB, or VIB metals; each X is C, N, or a combination thereof; n=1 or 2; and wherein the M′ atoms are substantially present as two-dimensional outer arrays of atoms within the two-dimensional array of crystal cells; the M″ atoms are substantially present as two-dimensional inner arrays of atoms within the two-dimensional array of crystal cells; and the two dimensional inner arrays of M″ atoms are sandwiched between the two-dimensional outer arrays of M′ atoms within the two-dimensional army of crystal cells. |
| FILED | Tuesday, April 05, 2022 |
| APPL NO | 17/713340 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 21/0602 (20130101) C01B 32/90 (20170801) C01B 32/907 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/20 (20130101) C01P 2002/70 (20130101) C01P 2002/85 (20130101) C01P 2006/40 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/02 (20130101) C30B 29/36 (20130101) C30B 29/38 (20130101) C30B 29/60 (20130101) C30B 29/68 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/58 (20130101) Original (OR) Class H01M 10/0525 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220231602 | Martinelli |
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| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert M. Martinelli (Temecula, California) |
| ABSTRACT | A buck voltage regulator device comprises a coupled inductor, a high-side switch electrically connected between an electrical energy source and a primary winding of the coupled inductor, a first low-side switch electrically connected between the primary winding and a ground node, a second low-side switch electrically connected between an auxiliary winding of the coupled inductor and the ground node, a first output node electrically connected to the primary winding, a second output node electrically connected to the auxiliary winding, a first output storage capacitor electrically connected to the primary winding between the first output node and the ground node, and a second output storage capacitor electrically connected to the auxiliary winding and between the second output node and the ground node. |
| FILED | Tuesday, September 28, 2021 |
| APPL NO | 17/449232 |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/088 (20130101) H02M 3/158 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220231684 | Mehrotra et al. |
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| FUNDED BY |
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| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Utkarsh Mehrotra (Raleigh, North Carolina); Douglas C. Hopkins (Raleigh, North Carolina) |
| ABSTRACT | Various examples are provided related to supercascode power switches that can be used in, e.g., HV and MV applications. This disclosure introduces a cascaded supercascode (CSC) power switch which can include a series of unit supercascode (USC) circuits; a control switch coupled in series with the series of USC circuits; and an external balancing network coupled to each of the n USC circuits. The series has a plurality of USC circuits, with each of the USC circuits including first and second switches coupled in series and an internal balancing network coupled across the first and second switches. A source of each of the USC circuits is a source of the first switch. The internal balancing network can include a capacitor connected between a gate of the second switch and the source of the first switch and a diode connected in parallel with the capacitor. |
| FILED | Saturday, January 15, 2022 |
| APPL NO | 17/576921 |
| CURRENT CPC | Pulse Technique H03K 17/102 (20130101) H03K 17/161 (20130101) H03K 17/6874 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220232181 | KELLY et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Michael W. KELLY (North Reading, Massachusetts); Megan H. BLACKWELL (Winchester, Massachusetts); Curtis COLONERO (Shrewsbury, Massachusetts); James WEY (ARLINGTON, Massachusetts); Christopher DAVID (Chelmsford, Massachusetts); Justin BAKER (North Andover, Massachusetts); Joseph COSTA (Bedford, Massachusetts) |
| ABSTRACT | When imaging bright objects, a conventional detector array can saturate, making it difficult to produce an image with a dynamic range that equals the scene's dynamic range. Conversely, a digital focal plane array (DFPA) with one or more m-bit counters can produce an image whose dynamic range is greater than the native dynamic range. In one example, the DFPA acquires a first image over a relatively brief integration period at a relatively low gain setting. The DFPA then acquires a second image over longer integration period and/or a higher gain setting. During this second integration period, counters may roll over, possibly several times, to capture a residue modulus 2′″ of the number of counts (as opposed to the actual number of counts). A processor in or coupled to the DFPA generates a high-dynamic range image based on the first image and the residues modulus 2′″. |
| FILED | Tuesday, January 18, 2022 |
| APPL NO | 17/577867 |
| CURRENT CPC | Pictorial Communication, e.g Television H04N 5/355 (20130101) H04N 5/2355 (20130101) H04N 5/23254 (20130101) H04N 5/23267 (20130101) H04N 5/35572 (20130101) H04N 5/35581 (20130101) Original (OR) Class H04N 5/37455 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20220227677 | Mehdipour et al. |
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| FUNDED BY |
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| APPLICANT(S) | Iman Mehdipour (Los Angeles, California); Raghubir Gupta (Cary, North Carolina); Gabriel D. Falzone (Los Angeles, California); Gaurav N. Sant (Los Angeles, California); Dante Simonetti (Los Angeles, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Iman Mehdipour (Los Angeles, California); Raghubir Gupta (Cary, North Carolina); Gabriel D. Falzone (Los Angeles, California); Gaurav N. Sant (Los Angeles, California); Dante Simonetti (Los Angeles, California) |
| ABSTRACT | Provided herein are systems for carbonation curing and CO2 mineralization of concrete composites and methods of manufacturing a carbonated concrete composite. A method of manufacturing a carbonated concrete composites includes contacting concrete with CO2-containing gas streams in the carbonation reactor having a gas stream inlet and an outlet to provide optimal gas flow distribution and gas velocity. The concrete precursor includes a binder, one or more aggregates, and water. A gas stream is received at the carbonation reactor. The gas stream includes carbon dioxide. The concrete precursor is maintained at a suitable temperature in the carbonation reactor to thereby react the concrete precursor with the gas stream to produce carbonate minerals in the carbonated concrete composite. |
| FILED | Monday, January 10, 2022 |
| APPL NO | 17/572448 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0013 (20130101) B01J 19/14 (20130101) B01J 19/26 (20130101) B01J 2219/00029 (20130101) B01J 2219/00155 (20130101) B01J 2219/00166 (20130101) B01J 2219/00243 (20130101) Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 11/245 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 14/06 (20130101) C04B 40/0231 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227724 | RADIC et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Oak Ridge National Laboratory (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zoran RADIC (San Diego, California); Carlo BALLATORE (La Jolla, California); Lukas GORECKI (Hradec Kralovy, Czech Republic); Palmer TAYLOR (La Jolla, California); Andrey KOVALEVSKY (Oak Ridge, Tennessee); Xiaolin CHENG (Oak Ridge, Tennessee) |
| ABSTRACT | In alternative embodiments, provided are uncharged bis-oxime antidotes that cross the blood-brain barrier (BBB) to catalyze the hydrolysis of organophosphate (OP)-inhibited human acetylcholinesterase (hAChE) in the central nerve system (CNS). In alternative embodiments, provided are pumps, devices, subcutaneous infusion devices, continuous subcutaneous infusion devices, infusion pens, needles, reservoirs, ampoules, a vial, a syringe, a cartridge, a disposable pen or jet injector, a prefilled pen or a syringe or a cartridge, a cartridge or a disposable pen or jet injector, a two chambered or multi-chambered pump, a syringe, a cartridge or a pen or a jet injector, comprising a compound as provided herein. |
| FILED | Thursday, May 21, 2020 |
| APPL NO | 17/613775 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 39/02 (20180101) Heterocyclic Compounds C07D 211/56 (20130101) C07D 295/13 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227826 | Thallapuranam et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
| INVENTOR(S) | Suresh Kumar Thallapuranam (Fayetteville, Arkansas); Shilpi Agrawal (Fayetteville, Arkansas); Ravi Kumar Gundampati (Fayetteville, Arkansas); Srinivas Jayanthi (Fayetteville, Arkansas); Tengjiao Wang (Fayetteville, Arkansas); Jake Jones (Fayetteville, Arkansas); Olivia Kolenc (Fayetteville, Arkansas); Ngoc Lam (Fayetteville, Arkansas); Isabelle Niyonshuti (Fayetteville, Arkansas); Kartik Balachandran (Fayetteville, Arkansas); Kyle Quinn (Fayetteville, Arkansas); Jingyi Chen (Fayetteville, Arkansas) |
| ABSTRACT | Engineered FGF1 and FGF2 polypeptides, polynucleotides encoding these polypeptides and DNA constructs, vectors and compositions including these engineered polypeptides are provided herein. The engineered FGF1 and FGF2 polypeptides are more stable than their wild-type counterparts and may be more effective at treating a variety of conditions that FGF1 and FGF2 are useful for treating such as wound healing. |
| FILED | Friday, January 28, 2022 |
| APPL NO | 17/587889 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 38/00 (20130101) Peptides C07K 14/501 (20130101) Original (OR) Class C07K 14/503 (20130101) C07K 2319/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220227921 | Bae et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chulsung Bae (Cohoes, New York); Woo-Hyung Lee (Troy, New York) |
| ABSTRACT | Embodiments of the invention relate to a novel class of polymers with superior mechanical properties and chemical stability, as compared to known polymers. These polymers are particularly well suited for use in anion exchange membranes (AEMs), including those employed in fuel cells. Novel methods for the manufacture of these polymers are also described. |
| FILED | Wednesday, February 23, 2022 |
| APPL NO | 17/652175 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 29/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 10/00 (20130101) C08G 61/02 (20130101) Original (OR) Class C08G 2261/20 (20130101) C08G 2261/45 (20130101) C08G 2261/124 (20130101) C08G 2261/146 (20130101) C08G 2261/312 (20130101) C08G 2261/332 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/14 (20130101) C09D 165/00 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 13/08 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/1004 (20130101) H01M 8/1039 (20130101) H01M 8/1072 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/50 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220228157 | Church et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | George M. Church (Cambridge, Massachusetts); Timothy M. Wannier (Cambridge, Massachusetts); Gabriel T. Filsinger (Cambridge, Massachusetts) |
| ABSTRACT | Provided herein, in some aspects are high efficiency gene editing methods in bacterial cells using single-stranded annealing proteins and/or single-stranded binding proteins. |
| FILED | Thursday, May 21, 2020 |
| APPL NO | 17/613216 |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 9/22 (20130101) C12N 15/70 (20130101) Original (OR) Class C12N 15/90 (20130101) C12N 15/746 (20130101) C12N 2510/00 (20130101) C12N 2795/00043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220228295 | Treadwell et al. |
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| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | LaRico Juan Treadwell (Albuquerque, New Mexico); James Nicholas (Albuquerque, New Mexico); Nelson S. Bell (Albuquerque, New Mexico) |
| ABSTRACT | Refractory transition metal-carbide (RTM-C) fibers were synthesized via the Forcespinning™ method. This method allows for simple and rapid synthesis of these RTM-C fibers with the ability to make grams of fibers quickly. |
| FILED | Monday, September 27, 2021 |
| APPL NO | 17/486600 |
| CURRENT CPC | Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0046 (20130101) D01D 5/0061 (20130101) Original (OR) Class Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 11/00 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 11/74 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220228426 | Bhandari et al. |
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| FUNDED BY |
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| APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mahabir Bhandari (Knoxville, Tennessee); Ahmed A. Hassan (Knoxville, Tennessee); Bipin Shah (Fairfax, Virginia); Derek Byrd (Knoxville, Tennessee) |
| ABSTRACT | A vacuum insulated glazing includes first and second spaced apart glass panes having perimeter portions defining a vacuum space between the glass panes. A vacuum valve is positioned at the perimeter portions of the glass panes and includes a valve body extending between the perimeter portions of the glass panes, and having first and second ends and a fluid conduit extending from the first end to the second end of the valve body and in fluid communication with the vacuum space. A one-way valve in the fluid conduit permits fluid flow from the vacuum space, and prevents fluid flow into the vacuum space. A suction fitting is provided for connecting the valve body to a suction device. An end seal between the perimeter portions of the glass panes is provided for hermetically sealing the vacuum space. A valve for a VIG and a method of making a VIG are also disclosed. |
| FILED | Friday, January 07, 2022 |
| APPL NO | 17/570931 |
| CURRENT CPC | Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 3/6612 (20130101) Original (OR) Class E06B 3/6775 (20130101) E06B 3/66333 (20130101) E06B 3/66342 (20130101) E06B 3/67326 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 15/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220229641 | Meister et al. |
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| FUNDED BY |
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| APPLICANT(S) | Reservoir Labs, Inc. (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Benoit J. Meister (New York, New York); Adithya Dattatri (Newark, Delaware) |
| ABSTRACT | An approach is presented to enhancing the optimization process in a polyhedral compiler by introducing compile-time versioning, i.e., the production of several versions of optimized code under varying assumptions on its run-time parameters. We illustrate this process by enabling versioning in the polyhedral processor placement pass. We propose an efficient code generation method and validate that versioning can be useful in a polyhedral compiler by performing benchmarking on a small set of deep learning layers defined for dynamically-sized tensors. |
| FILED | Monday, November 15, 2021 |
| APPL NO | 17/526611 |
| CURRENT CPC | Electric Digital Data Processing G06F 8/43 (20130101) Original (OR) Class G06F 8/71 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220229712 | Kegel et al. |
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| FUNDED BY |
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| APPLICANT(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew G. Kegel (Redmond, Washington); David A. Roberts (Wellesley, Massachusetts) |
| ABSTRACT | A neural network runs a known input data set using an error free power setting and using an error prone power setting. The differences in the outputs of the neural network using the two different power settings determine a high level error rate associated with the output of the neural network using the error prone power setting. If the high level error rate is excessive, the error prone power setting is adjusted to reduce errors by changing voltage and/or clock frequency utilized by the neural network system. If the high level error rate is within bounds, the error prone power setting can remain allowing the neural network to operate with an acceptable error tolerance and improved efficiency. The error tolerance can be specified by the neural network application. |
| FILED | Monday, April 04, 2022 |
| APPL NO | 17/712380 |
| CURRENT CPC | Electric Digital Data Processing G06F 11/076 (20130101) Original (OR) Class G06F 11/0706 (20130101) G06F 11/0793 (20130101) Computer Systems Based on Specific Computational Models G06N 3/02 (20130101) G06N 5/04 (20130101) G06N 20/00 (20190101) Image or Video Recognition or Understanding G06V 10/98 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220229908 | Peisert |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of Calofornia (Oakland, California) |
| INVENTOR(S) | Sean Peisert (San Rafael, California) |
| ABSTRACT | Disclosed herein are methods, systems, and devices for implementing trusted execution environments in the context of data security and data storage. Systems may include a login node comprising one or more processors configured to receive a request from a user, and a secure access port communicatively coupled to the login node and configured to process the request in accordance with one or more data access policies. Systems may further include a secure processing device communicatively coupled to the secure access port and comprising an encrypted portion configured to implement one or more data processing operations associated with the request. The systems may also include an encrypted data repository communicatively coupled to the secure processing device, the encrypted data repository comprising one or more storage devices, and being configured to encrypt and store data in the one or more storage devices. |
| FILED | Thursday, May 28, 2020 |
| APPL NO | 17/615034 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/31 (20130101) G06F 21/57 (20130101) Original (OR) Class G06F 21/78 (20130101) G06F 21/602 (20130101) G06F 21/604 (20130101) G06F 2221/034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220230422 | Shen et al. |
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| FUNDED BY |
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| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xipeng Shen (Raleigh, North Carolina); Lin Ning (Raleigh, North Carolina) |
| ABSTRACT | An exemplary clustering and computation reuse method comprises providing an artificial convolutional neural network; detecting that neuron vectors associated with an input layer and/or a hidden layer of the convolutional neural network are similar to one another; detecting similarities among the neuron vectors associated with the input layer and/or the at least one hidden layer during execution of a computer program; clustering similar neuron vectors into groups; computing a centroid vector for each group; performing, by a computer processor, computations using the centroid vector associated with one of the groups as a representative for one of the members of the group to generate an output for the computation, wherein the output is generated during execution of the computer program; and reusing, by the computer processor, the output for the computation involving the centroid vector for another computation involving another member of the group. |
| FILED | Wednesday, June 17, 2020 |
| APPL NO | 17/617438 |
| CURRENT CPC | Image or Video Recognition or Understanding G06V 10/82 (20220101) G06V 10/763 (20220101) G06V 10/7747 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220230882 | TELLEKAMP, JR. et al. |
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| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Marshall Brooks TELLEKAMP, JR. (Denver, Colorado); Andriy ZAKUTAYEV (Boulder, Colorado); Md Shahadat Hasan SOHEL (Littleton, Colorado) |
| ABSTRACT | Described herein are rock salt substrates and methods of making thereof that are useful as epitaxial substrates for semiconducting materials, including ultra-wide bandgap materials. Advantageously, the described rock salt substrates may be useful as substrates for Group III (Al, Ga, In)—N substrate allowing for pseudomorphic growth of novel, desirable materials. The rock salt may be provided as a bulk material or deposited as a thin film. These substrates may allow for generation of high Al content semiconductor devices with ultra-wide bandgap and other useful properties. |
| FILED | Thursday, January 20, 2022 |
| APPL NO | 17/580198 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/34 (20130101) C23C 14/0664 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/186 (20130101) C30B 29/406 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/2015 (20130101) H01L 21/2026 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220230883 | Chowdhury et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Srabanti Chowdhury (San Ramon, California); Dong Ji (San Jose, California) |
| ABSTRACT | In certain examples, methods and semiconductor structures are directed to use of a doped buried region (e.g., Mg-dopant) including a III-Nitride material and having a diffusion path (“ion diffusion path”) that includes hydrogen introduced by using ion implantation via at least one ion species. An ion implantation thermal treatment causes hydrogen to diffuse through the ion implanted path and causes activation of the buried region. In more specific examples in which such semiconductor structures have an ohmic contact region at which a source of a transistor interfaces with the buried region, the ohmic contact region is without etching-based damage due at least in part to the post-ion implantation thermal treatment. |
| FILED | Friday, May 15, 2020 |
| APPL NO | 17/609194 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0254 (20130101) H01L 21/266 (20130101) H01L 21/3245 (20130101) H01L 21/26546 (20130101) Original (OR) Class H01L 29/2003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220231214 | Sonde et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Epir, Inc. (Bolingbrook, Illinois) |
| ASSIGNEE(S) | Epir, Inc. (Bolingbrook, Illinois) |
| INVENTOR(S) | Sushant Sonde (Westmont, Illinois); Yong Chang (Naperville, Illinois); Silviu Velicu (Willowbrook, Illinois); Srinivasan Krishnamurthy (Cupertino, California) |
| ABSTRACT | A Terahertz Source and Detector device is provided that includes a nanostructured metasurface configured to transmit fully into a layer of absorbing material below the metasurface to achieve transparent conductivity in the visible spectrum region, wherein the metasurface is composed of crystalline material with very high mobility. The crystalline material can be composed of HgCdTe. The HgCdTe material can have a bandgap of about 700 meV. The intrinsic carrier concentration can be 1012 cm−3 at 300K. |
| FILED | Monday, November 01, 2021 |
| APPL NO | 17/516228 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 37/025 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220231296 | Sakshaug et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Group14 Technologies, Inc. (Woodinville, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Avery J. Sakshaug (Snohomish, Washington); Henry R. Costantino (Woodinville, Washington); Aaron M. Feaver (Seattle, Washington); Leah A. Thompkins (Seattle, Washington); Katharine Geramita (Seattle, Washington); Benjamin E. Kron (Seattle, Washington); Sarah Fredrick (Denver, Colorado); Farshid Afkhami (Lake Stevens, Washington); Adam Strong (Lake Forest Park, Washington) |
| ABSTRACT | Composites of silicon and various porous scaffold materials, such as carbon material comprising micro-, meso- and/or macropores, and methods for manufacturing the same are provided. The compositions find utility in various applications, including electrical energy storage electrodes and devices comprising the same. |
| FILED | Tuesday, December 29, 2020 |
| APPL NO | 17/137223 |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/524 (20130101) C04B 38/0051 (20130101) C04B 38/0064 (20130101) C04B 41/009 (20130101) C04B 41/85 (20130101) C04B 41/5096 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/04 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/133 (20130101) H01M 4/134 (20130101) H01M 4/362 (20130101) H01M 4/364 (20130101) H01M 4/366 (20130101) H01M 4/386 (20130101) H01M 4/0416 (20130101) H01M 4/587 (20130101) Original (OR) Class H01M 4/625 (20130101) H01M 10/0525 (20130101) H01M 2004/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220231309 | Evans et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ESS TECH, INC. (Wilsonville, Oregon) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Craig E. Evans (West Linn, Oregon); Sean Casey (Portland, Oregon); Yang Song (West Linn, Oregon) |
| ABSTRACT | A redox flow battery may include: a membrane interposed between a first electrode positioned at a first side of the membrane and a second electrode positioned at a second side of the membrane opposite to the first side; a first flow field plate comprising a plurality of positive flow field ribs, each of the plurality of positive flow field ribs contacting the first electrode at first supporting regions on the first side; and the second electrode, including an electrode spacer positioned between the membrane and a second flow field plate, the electrode spacer comprising a plurality of main ribs, each of the plurality of main ribs contacting the second flow field plate at second supporting regions on the second side, each of the second supporting regions aligned opposite to one of the plurality of first supporting regions. As such, a current density distribution at a plating surface may be reduced. |
| FILED | Friday, March 04, 2022 |
| APPL NO | 17/653620 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/8803 (20130101) H01M 4/8817 (20130101) H01M 4/8828 (20130101) H01M 8/20 (20130101) H01M 8/188 (20130101) H01M 8/0239 (20130101) H01M 8/0245 (20130101) H01M 8/0258 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220231350 | LIPSON |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Albert L. LIPSON (Oak Park, Illinois) |
| ABSTRACT | A method for recovering a lithium electrolyte salt from spent batteries comprises first extracting electrolyte from shredded batteries (e.g., spent batteries at the end of their useful lifetime) with an organic carbonate solvent; concentrating the extracted electrolyte in vacuo to form a solid lithium electrolyte salt that is solvated with the organic carbonate; and then extracting solvent from the solvated, solid lithium electrolyte salt with supercritical CO2 to purify the lithium electrolyte salt sufficiently for reuse in lithium batteries. In the first extraction, the organic carbonate solvent is selected based on the solubility of the lithium electrolyte salt in the solvent, as well as the volatility of the solvent to facilitate the concentration process. The supercritical CO2 is preferably held at a pressure in the range of about 1,500 to about 30,000 psi and is passed through a bed or column of the solvated salt. |
| FILED | Friday, January 15, 2021 |
| APPL NO | 17/149859 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/54 (20130101) Original (OR) Class H01M 10/0525 (20130101) H01M 10/0562 (20130101) H01M 10/0569 (20130101) H01M 2300/008 (20130101) H01M 2300/0028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220231760 | DeVore et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Peter Thomas Setsuda DeVore (Livermore, California); Apurva Shantharaj Gowda (Mountain View, California); David Simon Perlmutter (Oakland, California); Joshua Linne Olson (Manassas, Virginia); Jason Thomas Chou (Walnut Creek, California) |
| ABSTRACT | Methods, devices and systems for providing accurate measurements of timing errors using optical techniques are described. An example timing measurement device includes an optical hybrid that receives two optical pulse trains and produces two or more phase shifted optical outputs. The timing measurement device further includes two or more optical filters that receive the outputs of the optical hybrid to produce multiple pulse signals with distinctive frequency bands. The device also includes one or more photodetectors and analog-to-digital converters to receive to produce electrical signals in the digital domain corresponding to the optical outputs of the hybrid. A timing error associated with the optical pulse trains can be determined using the electrical signals in digital domain based on a computed phase difference between a first frequency band signal and a second frequency band signal and a computed frequency difference between the first frequency band signal and the second frequency band. |
| FILED | Wednesday, February 09, 2022 |
| APPL NO | 17/667999 |
| CURRENT CPC | Transmission H04B 10/0795 (20130101) Original (OR) Class H04B 10/2575 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220232111 | Ford et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anthony M. Ford (Bristol Avon, United Kingdom); Jonathan P. Beecroft (Bristol Avon, United Kingdom); Duncan Roweth (Bristol Avon, United Kingdom); Edwin L. Froese (Burnaby British Columbia, Canada) |
| ABSTRACT | Systems and methods are described for providing per traffic class routing of data within a network. A network switch has the capability to classify traffic data based on High Performance Computing (HPC) related characteristics. Traffic classes are defined based on aspects of HPC, such as routing, ordering, redirection, quiesce, HPC protocol configuration, and telemetry. A switch can receive packets at an ingress port of a switch fabric, and determine traffic classifications for the packets. The traffic classification is selected from a group of defined traffic classes. Then, the switch can generate a fabric specific flag for the at least one packet that indicates the determined traffic classification, where the fabric specific flag is used for routing packets based on their assigned traffic classification. Examples of traffic classes include: low latency class; dedicated access class; bulk data class; best efforts class; and scavenger class. |
| FILED | Monday, March 23, 2020 |
| APPL NO | 17/594735 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 47/22 (20130101) H04L 47/2441 (20130101) H04L 69/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 20220227001 | Fry |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Mark A. Fry (Marco Island, Florida) |
| ABSTRACT | Systems and methods are described, and an example system includes a transport bin configured to carry a baggage item and having spatial reference frame marking detectable by electromagnetic scan and by machine vision. The system includes a robotic arm apparatus at an inspection area, and includes a switched path baggage conveyor that, responsive to electromagnetic scan detection of an object-of-interest (OOI) within the baggage item, conveys the transport bin to the inspection area. The electromagnetic scan generates OOI geometric position information indicating geometric position of the OOI relative to the spatial reference frame marking. The robotic arm apparatus, responsive to receiving the transport bin, uses machine vision to detect orientation of the spatial reference frame marking, then translates OOI geometric position information to local reference frame, for robotic opening of the baggage item, and robotic accessing and contact swab testing on the OOI. |
| FILED | Tuesday, February 01, 2022 |
| APPL NO | 17/590456 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/043 (20130101) B25J 9/1612 (20130101) B25J 9/1697 (20130101) Original (OR) Class B25J 13/087 (20130101) B25J 19/023 (20130101) B25J 19/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220228953 | DiCicco et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Joseph DiCicco (Cape May Court House, New Jersey); Paul Flanigan (Northfield, New Jersey); Joshua Stroker (Somers Point, New Jersey); James Deline (Egg Harbor City, New Jersey) |
| ABSTRACT | A kit-of-parts for assembling an apparatus for verifying Explosive Trace Detector responses includes an alignment tool and a dispenser. The alignment tool has a body with a top cavity open on a top side and configured to receive the dispenser housing or a sampling medium head of a sampling medium. The sampling medium head has a sample collection area. The body has a bottom cavity to receive a hammer arm. The body has one or more sampling media cavities disposed between the top cavity and the bottom cavity, each configured to receive another sampling medium having a respective sample collection area. The top cavity and sampling media cavities are in communication with each other via a common slot. The top cavity and sampling media cavities are configured to receive different sampling media and to align the dispenser housing with the sample collection area of each of the different sampling media. |
| FILED | Thursday, April 07, 2022 |
| APPL NO | 17/715584 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/02 (20130101) Original (OR) Class G01N 2001/022 (20130101) G01N 2001/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220229017 | Oxley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Rhode Island Board of Trustees (Kingston, Rhode Island) |
| ASSIGNEE(S) | University of Rhode Island Board of Trustees (Kingston, Rhode Island) |
| INVENTOR(S) | Jimmie Oxley (Narragansett, Rhode Island); James L. Smith (Narragansett, Rhode Island); Alexander Yevdokimov (Norwich, Connecticut) |
| ABSTRACT | The present disclosure describes an improved sample preparation technique, swab, swab holder and solvent for the removal of trace chemical materials from swabs and delivery of the trace materials into a mass spectrometer (MS) or an ion mobility spectrometer (IMS). The devices and techniques aid the delivery of the analyte into the instrument inlet and concurrently serves as an ionization source. The technique includes the steps of positioning or shaping the swab so that a pointed analyte release area is directed toward the inlet of the MS or IMS, adding a solvent to the swab and charging the swab to create an ionized analyte spray (Taylor Cone spray) into the inlet of the detection instrument. Solvent may include a chemical for depressing the ionization of residual solvent or enhancing the ionization of the desired analyte and this chemical may serve as an internal standard or benchmark. |
| FILED | Thursday, April 07, 2022 |
| APPL NO | 17/715287 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/622 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 49/26 (20130101) H01J 49/0031 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20220227074 | Belcher et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois); United States of America as represented by the Administrator of NASA (Hampton, Virginia) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois); United States of America as represented by the Administrator of NASA (Hampton, Virginia) |
| INVENTOR(S) | Marcus Anthony Belcher (Sammamish, Washington); Robert Alan Martin (Yorktown, Virginia) |
| ABSTRACT | A method for laying up a composite material includes steps of (1) depositing the composite material onto a substrate; (2) compacting the composite material with a compaction roller, the compaction roller and the substrate defining a nip; and (3) projecting a plasma flume proximate the nip to heat at least one of the composite material and the substrate. |
| FILED | Wednesday, November 03, 2021 |
| APPL NO | 17/517947 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 35/08 (20130101) B29C 70/34 (20130101) Original (OR) Class B29C 70/54 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2101/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220229014 | Pourmand et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nader Pourmand (San Mateo, California); Boaz Vilozny (Santa Cruz, California); Paolo Actis (London, United Kingdom); R. Adam Seger (Santa Cruz, California) |
| ABSTRACT | Disclosed are methods and devices for detection of ion migration and binding, utilizing a nanopipette adapted for use in an electrochemical sensing circuit. The nanopipette may be functionalized on its interior bore with metal chelators for binding and sensing metal ions or other specific binding molecules such as boronic acid for binding and sensing glucose. Such a functionalized nanopipette is comprised in an electrical sensor that detects when the nanopipette selectively and reversibly binds ions or small molecules. Also disclosed is a nanoreactor, comprising a nanopipette, for controlling precipitation in aqueous solutions by voltage-directed ion migration, wherein ions may be directed out of the interior bore by a repulsing charge in the bore. |
| FILED | Tuesday, December 21, 2021 |
| APPL NO | 17/557549 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/021 (20130101) B01L 3/50273 (20130101) B01L 2300/0896 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 35/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3277 (20130101) G01N 27/44791 (20130101) Original (OR) Class G01N 33/48721 (20130101) Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 60/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220229703 | Liaghati |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Amir Leon Liaghati (Huntsville, Alabama) |
| ABSTRACT | A system selects a telemetry allocation for the transmission of data from multiple transmitters. An allocation matrix defines a split ratio for data generated by a data source that is split between transmitters. The split ratio is defined for each data source of a plurality of data sources. (A) A storage buffer model is executed based on the allocation matrix to simulate a buffer that stores data from each data source that exceeds a download bandwidth value. (B) Performance parameter values are stored in association with the allocation matrix. (C) The allocation matrix is updated to redefine at least one split ratio. (D) (A) through (C) is repeated with the allocation matrix replaced with the updated allocation matrix until each unique permutation of values for the split ratio is processed. An allocation matrix is selected from allocation matrices stored in (B) based on the plurality of performance parameter values. |
| FILED | Tuesday, October 05, 2021 |
| APPL NO | 17/493996 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/5022 (20130101) G06F 9/5044 (20130101) Original (OR) Class G06F 11/323 (20130101) G06F 11/3089 (20130101) G06F 11/3466 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Smithsonian Institution (SI)
| US 20220225793 | Kopp |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Smithsonian Institution (Washington, District of Columbia) |
| ASSIGNEE(S) | Smithsonian Institution (Washington, District of Columbia) |
| INVENTOR(S) | Graham Michael Kopp (Herndon, Virginia) |
| ABSTRACT | Systems and methods for securely framing an enclosure with an easily formed and integrated inert material, thereby providing a non-reactive environment for securing one or more objects. |
| FILED | Friday, January 14, 2022 |
| APPL NO | 17/576900 |
| CURRENT CPC | Special Furniture, Fittings, or Accessories for Shops, Storehouses, Bars, Restaurants or the Like; Paying Counters A47F 3/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220225795 | Kopp |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Smithsonian Institution (Washington, District of Columbia) |
| ASSIGNEE(S) | Smithsonian Institution (Washington, District of Columbia) |
| INVENTOR(S) | Graham Michael Kopp (Herndon, Virginia) |
| ABSTRACT | Systems and methods for securely framing an enclosure with an easily formed and integrated inert material, thereby providing a non-reactive environment for securing one or more objects. |
| FILED | Friday, January 14, 2022 |
| APPL NO | 17/576894 |
| CURRENT CPC | Special Furniture, Fittings, or Accessories for Shops, Storehouses, Bars, Restaurants or the Like; Paying Counters A47F 5/0068 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220230820 | Pula et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Smithsonian Institution (Washington, District of Columbia) |
| ASSIGNEE(S) | Smithsonian Institution (Washington, District of Columbia) |
| INVENTOR(S) | Timothy Pula (Fredericksburg, Virginia); Geoffrey Moore (Arlington, Virginia) |
| ABSTRACT | Systems and methods for providing a replacement touchless button for initiating an action upon proximate detection of a solid object near the top of the touchless button. The action is triggered by determining that the solid object is within a predetermined distance from the top of the button. The action is accomplished by the closing of an electrical circuit within the touchless button, the button being configured to replace a push button without modification of a panel housing the push button. The button contains and supports, within its structure, all electrical and physical components needed to operate a device that can be triggered via a push button. The button serves as a direct replacement for a push button with no modifications to existing systems or controls regularly triggered by a push button. |
| FILED | Friday, January 14, 2022 |
| APPL NO | 17/576486 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0202 (20130101) Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 11/00 (20130101) Original (OR) Class H01H 2229/022 (20130101) Pulse Technique H03K 17/945 (20130101) H03K 2017/9455 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20220227885 | HANSEN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | James E. HANSEN (Guilford, Connecticut); Peter GLAZER (Guilford, Connecticut) |
| ABSTRACT | The invention provides methods for selective targeting of live cells, which have undergone or are undergoing radiation or chemotherapy, at a site of interest with a cell-penetrating polypeptide. In one embodiment of the invention, the method comprises contacting the live cells with a cell-penetrating polypeptide comprising cell-penetrating determinants so that the cell-penetrating polypeptide binds extracellular DNA near or around the live cells so as to form a complex or association therewith such that the complex or associated polypeptide-DNA so bound bind the live cells and penetrates the live cells thereby selectively targeting live cells at a site of interest with a cell-penetrating polypeptide. |
| FILED | Monday, December 27, 2021 |
| APPL NO | 17/562727 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6843 (20170801) A61K 2039/505 (20130101) Peptides C07K 16/18 (20130101) C07K 16/44 (20130101) Original (OR) Class C07K 2317/77 (20130101) C07K 2317/622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Treasury (TREASURY)
| US 20220227159 | Phillips et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WAVEFRONT TECHNOLOGY, INC. (Paramount, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Roger Winston Phillips (Santa Rosa, California); Christopher Chapman Rich (Rancho Palos Verdes, California); Joel Mikael Petersen (Valley Village, California) |
| ABSTRACT | A document, product, or package, such as a banknote, passport or the like comprises structures having dichroic effects that change color with viewing angle in both transmission and reflection. Such structures can be useful as security features that counter the ability to effectively use counterfeit documents, products, packages, etc. |
| FILED | Thursday, August 26, 2021 |
| APPL NO | 17/445996 |
| CURRENT CPC | Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus B42D 25/29 (20141001) B42D 25/45 (20141001) B42D 25/351 (20141001) B42D 25/355 (20141001) B42D 25/373 (20141001) Original (OR) Class B42D 25/378 (20141001) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 20220232111 | Ford et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anthony M. Ford (Bristol Avon, United Kingdom); Jonathan P. Beecroft (Bristol Avon, United Kingdom); Duncan Roweth (Bristol Avon, United Kingdom); Edwin L. Froese (Burnaby British Columbia, Canada) |
| ABSTRACT | Systems and methods are described for providing per traffic class routing of data within a network. A network switch has the capability to classify traffic data based on High Performance Computing (HPC) related characteristics. Traffic classes are defined based on aspects of HPC, such as routing, ordering, redirection, quiesce, HPC protocol configuration, and telemetry. A switch can receive packets at an ingress port of a switch fabric, and determine traffic classifications for the packets. The traffic classification is selected from a group of defined traffic classes. Then, the switch can generate a fabric specific flag for the at least one packet that indicates the determined traffic classification, where the fabric specific flag is used for routing packets based on their assigned traffic classification. Examples of traffic classes include: low latency class; dedicated access class; bulk data class; best efforts class; and scavenger class. |
| FILED | Monday, March 23, 2020 |
| APPL NO | 17/594735 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 47/22 (20130101) H04L 47/2441 (20130101) H04L 69/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 20220227652 | BLANEY et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lee BLANEY (Baltimore, Maryland); Utsav SHASHVATT (Baltimore, Maryland); Charles PORTNER (Baltimore, Maryland) |
| ABSTRACT | Separation methods and systems for converting high concentrations of animal wastes and other nutrient-rich organic materials into nutrients and other useful products such as struvite and potassium struvite. Advantageously, the system and methods do not require the addition of external chemicals other than an acid and a base. |
| FILED | Monday, April 04, 2022 |
| APPL NO | 17/712455 |
| CURRENT CPC | Separation B01D 33/03 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 8/005 (20130101) B01J 10/002 (20130101) B01J 19/18 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/20 (20130101) C02F 1/5209 (20130101) C02F 1/5236 (20130101) C02F 1/5281 (20130101) C02F 11/121 (20130101) Original (OR) Class C02F 2101/105 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 20220228507 | Faisal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Mohammad G. Faisal (Palm Beach Gardens, Florida); David Maliniak (Guilford, Connecticut) |
| ABSTRACT | An inner shroud assembly of a variable vane actuation system for a gas turbine engine includes a shroud assembly comprising a multiple of forward shroud segments and a respective multiple of aft shroud segments. A multiple of variable vanes are rotationally retained at an inboard trunion between the forward and aft shroud segments of the shroud assembly. A retainer assembly includes a multiple of retainer ring segments that retain the forward and aft shroud segments together. The inner shroud assembly is assembled into an engine case with an inboard extending feature that engages with an outer diameter feature of each of the multiple of retainer ring segments. |
| FILED | Monday, January 18, 2021 |
| APPL NO | 17/151425 |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/165 (20130101) Original (OR) Class F01D 25/26 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/11 (20130101) F05D 2240/12 (20130101) F05D 2240/14 (20130101) F05D 2260/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220229227 | Puckett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| ASSIGNEE(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| INVENTOR(S) | Matthew Wade Puckett (Phoenix, Arizona); Chad Fertig (Bloomington, Minnesota); Steven Tin (Edina, Minnesota) |
| ABSTRACT | Techniques relating to an improved optical waveguide are described. The optical waveguide includes an upper and lower waveguide that each comprise a first and second layer, in which photons are transferred from the lower waveguide to the upper waveguide. A structured subwavelength coupling region is included, for example, in the first upper waveguide layer. The fill factor of the subwavelength grating coupling region is increased in the direction of light propagation to increase the index of refraction of the structured subwavelength coupling region and therefore improve photon transfer from the lower waveguide. Additionally, the width of the optical waveguide (at least along the structured subwavelength coupling region) remains constant as the fill factor increases. |
| FILED | Friday, November 19, 2021 |
| APPL NO | 17/531441 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/14 (20130101) G02B 6/34 (20130101) G02B 6/124 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220229632 | GOVIA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RAYTHEON BBN TECHNOLOGIES CORP. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Luke Colin Gene GOVIA (Somerville, Massachusetts); William Daniel KALFUS (River Vale, New Jersey); Guilhem Jean RIBEILL (Bedford, Massachusetts); Graham Earle ROWLANDS (Arlington, Massachusetts); Hari Kiran KROVI (Lexington, Massachusetts); Thomas Akira OHKI (Arlington, Massachusetts) |
| ABSTRACT | A reservoir computer. In some embodiments, the reservoir computer includes a Duffing oscillator, and a readout circuit, and the readout circuit is configured to calculate a plurality of products, each of the products being calculated by multiplying a sample, of a plurality of samples of a signal from the Duffing oscillator, by a respective weight of a plurality of weights. |
| FILED | Tuesday, August 03, 2021 |
| APPL NO | 17/393372 |
| CURRENT CPC | Electric Digital Data Processing G06F 7/50 (20130101) G06F 7/388 (20130101) Original (OR) Class G06F 7/523 (20130101) G06F 7/5443 (20130101) Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 15/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, July 21, 2022.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-applications-20220721.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page