FedInvent™ Patent Applications
Application Details for Thursday, August 25, 2022
This page was updated on Friday, August 26, 2022 at 05:32 PM GMT
Department of Health and Human Services (HHS)
| US 20220264872 | March et al. |
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| FUNDED BY |
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| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Keith L. March (Carmel, Indiana); Meijing Wang (Carmel, Indiana) |
| ABSTRACT | The present disclosure provides methods and compositions for treating tissue to preserve and/or rescue tissue from ischemic and/or reperfusion injury and methods for assessing ischemic and/or injuries in cardiac tissue. The disclosed compositions comprise at least a portion of mesenchymal stem cell-conditioned medium. |
| FILED | Monday, February 07, 2022 |
| APPL NO | 17/666528 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0226 (20130101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/00 (20130101) C12N 5/0667 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5088 (20130101) G01N 2570/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220264897 | BLOOMQUIST et al. |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
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| INVENTOR(S) | Jeffrey R BLOOMQUIST (Gainesville, Florida); Edmund NORRIS (Gainesville, Florida) |
| ABSTRACT | Described herein are compositions and methods relating to insecticides. In additional embodiments according to the present disclosure, administration devices and methods of such are also described. In certain aspects, compositions and methods as described herein comprise “Cha Plu” (Piper sarmentosum) extract. In certain aspects, compositions and methods as described herein further comprise an insecticide, for example natural pyrethrins or derivatives thereof. Compositions and methods as described herein utilize effective amounts of active ingredients of such compositions to induce knockdown and/or mortality of pests based on synergistic action of the “Cha Plu” (Piper sarmentosum) extract and natural pyrethrins together. |
| FILED | Sunday, August 23, 2020 |
| APPL NO | 17/635579 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 43/16 (20130101) A01N 65/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265137 | Dana et al. |
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| APPLICANT(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts) |
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| INVENTOR(S) | Reza Dana (Newton, Massachusetts); Francisco L. Amparo Pulido (Cambridge, Massachusetts); Haobing Wang (Newton, Massachusetts) |
| ABSTRACT | The technology described in this document can be embodied in systems and computer-implemented methods for determining a score representing an amount of staining of the cornea. The methods include obtaining a digital image of the cornea stained with a tracer material, receiving a selection of a portion of the image, and processing, by a processing device, the selection to exclude areas with one or more artifacts to define an evaluation area. For each of a plurality of pixels within the evaluation area, a plurality of Cartesian color components are determined and a hue value in a polar coordinate based color space is calculated from the components. An amount of staining of the cornea is then determined as a function of the hue value. The methods also include assigning a score to the evaluation area based on the amount of staining calculated for the plurality of pixels. |
| FILED | Friday, May 06, 2022 |
| APPL NO | 17/738783 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/14 (20130101) A61B 3/0025 (20130101) Original (OR) Class A61B 5/0071 (20130101) A61B 5/1032 (20130101) A61B 5/4848 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265353 | Gildea et al. |
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| APPLICANT(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio); NEW COS, INC. (Cleveland, Ohio) |
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| INVENTOR(S) | Thomas Gildea (Cleveland, Ohio); Keith Grafmeyer (Cleveland, Ohio) |
| ABSTRACT | Systems and methods are provided for designing a stent for placement within an airway of a patient. Computer executable instructions are executable by a processor to provide an image segmenter, a graphic user interface, and a model generator. The image segmenter segments at least one image of a region of interest to provide a three-dimensional airway model representing at least a portion of the airway. The graphic user interface prompts a user to select a plurality of locations at an within the airway model and a corresponding plurality of diameters for the plurality of locations. The model generator constructs a stent model from the selected locations and diameters. |
| FILED | Monday, July 13, 2020 |
| APPL NO | 17/626344 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/032 (20130101) A61B 6/5217 (20130101) A61B 34/10 (20160201) Original (OR) Class A61B 2034/102 (20160201) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265563 | Kim et al. |
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| APPLICANT(S) | Peptron, Inc. (Daejeon, South Korea); The United States, as represented by the Secretary, Department of Health and Human Services (Rockville, Maryland) |
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| INVENTOR(S) | Dong Seok Kim (Columbia, Maryland); Hee Kyung Kim (Daejeon, South Korea); Nigel H. Greig (Phoenix, Maryland) |
| ABSTRACT | The present disclosure provides a method for delivering a neuroprotective polypeptide to at least a portion of a central nervous system (CNS) of a subject. The method includes administering to the systemic blood circulation of the subject a therapeutically effective amount of a neuroprotective polypeptide by a controlled-release formulation or a device providing a sustained release of the neuroprotective polypeptide including at least one neuroprotective polypeptide selected from the group consisting of GLP-1, exendin-4, or a therapeutically effective GLP-1 or exendin-4 analogue; the neuroprotective polypeptide binds to and activates a receptor that binds at least one of GLP-1, exendin-4, or a combination thereof; and the controlled-release neuroprotective formulation or the sustained release of the neuroprotective polypeptide enhances the delivery of the neuroprotective polypeptide across a blood-brain barrier (BBB) of the subject to at least a portion of the CNS relative to a rapid release formulation of the neuroprotective polypeptide. Also disclosed is a method of treating a subject with a CNS-related disease or reducing at least one symptom of a CNS-related disease in a subject in need thereof. |
| FILED | Tuesday, November 09, 2021 |
| APPL NO | 17/522687 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/4866 (20130101) A61K 9/5031 (20130101) Original (OR) Class A61K 38/26 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/14228 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/16 (20180101) A61P 25/28 (20180101) A61P 25/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265607 | Philpot et al. |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
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| INVENTOR(S) | Benjamin D. Philpot (Durham, North Carolina); Kiran Ramesh Bettadapur (Bengaluru, India); Hyeong-Min Lee (Cordova, Tennessee); Hanna Vihma (Chapel Hill, North Carolina) |
| ABSTRACT | The present invention provides methods and compositions for inducing expression of Ube3a in a cell and treating Angelman syndrome in a subject. |
| FILED | Thursday, July 16, 2020 |
| APPL NO | 17/625604 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/42 (20130101) A61K 31/166 (20130101) A61K 31/4155 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265643 | NEWMAN et al. |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (Bethesda, Maryland) |
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| INVENTOR(S) | Amy Hauck NEWMAN (Phoenix, Maryland); Vivek KUMAR (Baltimore, Maryland); Anver Basha SHAIK (Baltimore, Maryland) |
| ABSTRACT | Disclosed herein are novel methods of treating pain in a patient in need thereof by providing to the patient a selective dopamine D3 receptor antagonist/partial agonist which when used with an opioid analgesic, can mitigate the development of opioid dependence, by preventing the need for dose escalation while either maintaining the opioid analgesic effect or providing analgesia with a lower dose of the opioid. In addition, the D3 antagonists/partial agonists described herein may be used to augment the effectiveness of current Medication Assisted Treatment regimens (e.g. methadone or buprenorphine) for the treatment of opioid use disorders. |
| FILED | Friday, May 06, 2022 |
| APPL NO | 17/738301 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/485 (20130101) A61K 31/496 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/36 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265660 | Zuo et al. |
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| APPLICANT(S) | Ting Therapeutics LLC (Omaha, Nebraska) |
| ASSIGNEE(S) | Ting Therapeutics LLC (Omaha, Nebraska) |
| INVENTOR(S) | Jian Zuo (Omaha, Nebraska); Tal Teitz (Omaha, Nebraska) |
| ABSTRACT | Method, kit and pharmaceutical compositions using an inhibitor of EGFR signaling for prevention or treatment of hearing loss are described. |
| FILED | Wednesday, May 04, 2022 |
| APPL NO | 17/736330 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) A61K 31/506 (20130101) A61K 31/519 (20130101) Original (OR) Class A61K 31/4439 (20130101) A61K 31/4709 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/16 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265669 | GAVATHIOTIS et al. |
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| APPLICANT(S) | ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York) |
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| INVENTOR(S) | Evripidis GAVATHIOTIS (Roslyn, New York); Bogos AGIANIAN (Bayside, New York) |
| ABSTRACT | The disclosure provides compounds of Formula I (Formula I) (c) And the pharmaceutically acceptable salts thereof. The A, B, C, and D rings and the variables RA, RB, RC, RD, L0, L1, L2, and L2, are defined herein. Compounds and salts of Formula I are useful as inhibitors of RAF kinase dimerization, including dimerization of wild type and mutant BRAF kinases. The disclosure includes pharmaceutical compositions comprising a compound or salt of Formula I. The disclosure also includes methods of treating a cancer susceptible to treatment with an inhibitor of BRAF dimers or BRAF dimerization, comprising administering a therapeutically effective amount of a compound or salt of Formula I to a patient in need of such treatment. These cancers susceptible to treatment with an inhibitor of BRAF dimers or BRAF dimerization include melanoma, thyroid cancer, hairy cell leukemia, ovarian cancer, lung cancer, and colorectal cancer. |
| FILED | Tuesday, February 25, 2020 |
| APPL NO | 17/432589 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/495 (20130101) A61K 31/506 (20130101) A61K 31/5025 (20130101) A61K 31/5377 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 295/13 (20130101) C07D 487/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265677 | Blau et al. |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Helen M. Blau (Stanford, California); Adelaida R. Palla (Stanford, California); Andrew Tri Van Ho (Paris, France) |
| ABSTRACT | Provided herein are compositions for preventing or treating muscle conditions such as muscle damage, injury, or atrophy. In some embodiments, the compositions comprise a prostaglandin E2 (PGE2) compound and a myotoxin. In some embodiments, the muscle damage, injury, or atrophy is the result of a nerve injury, a surgical procedure, or a traumatic injury. Methods of promoting muscle regeneration and methods of increasing muscle mass are also provided herein. |
| FILED | Wednesday, August 11, 2021 |
| APPL NO | 17/399490 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/46 (20130101) A61K 31/47 (20130101) A61K 31/167 (20130101) A61K 31/245 (20130101) A61K 31/445 (20130101) A61K 31/5575 (20130101) Original (OR) Class A61K 33/00 (20130101) A61K 33/06 (20130101) A61K 33/24 (20130101) A61K 33/32 (20130101) A61K 38/465 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265689 | Garcia Lerma et al. |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA ,AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (Bethesda, Maryland) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA , as represented by the Secretary, Department of Health and Human (Bethesda, Maryland) |
| INVENTOR(S) | Jose Gerardo Garcia Lerma (Decatur, Georgia); Ivana Mabel Massud (Atlanta, Georgia); Walid M. Heneine (Atlanta, Georgia) |
| ABSTRACT | Disclosed is the use of a nucleoside reverse transcriptase inhibitor, a nucleotide reverse transcriptase inhibitor, and an integrase inhibitor prior to an exposure to a potential human immunodeficiency virus (HIV) infection, to protect the subject from the HIV infection. In some embodiments, a prophylactically effective amount of emtricitabine (FTC), a prophylactically effective amount of tenofovir or a tenofovir prodrug, such as tenofovir alafenamide (TAF) or tenofovir disoproxil fumarate (TDF), a prophylactically effective amount of the integrase inhibitor elvitegravir (EVG), and optionally cobicistat (COBI) are used to inhibit or prevent an HIV infection, wherein these agents are administered only prior to the exposure. In specific non-limiting examples, only one dose of the anti-retroviral viral agents is administered to a subject prior to the exposure. |
| FILED | Monday, January 27, 2020 |
| APPL NO | 17/628170 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) A61K 31/513 (20130101) A61K 31/675 (20130101) Original (OR) Class A61K 31/5377 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265699 | Arnold et al. |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
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| INVENTOR(S) | Katelyn Arnold (Chapel Hill, North Carolina); Jian Liu (Chapel Hill, North Carolina); Rafal Pawlinski (Chapel Hill, North Carolina); Brian Cooley (Chapel Hill, North Carolina) |
| ABSTRACT | Disclosed is a method of treating liver ischemia reperfusion (I/R) injury in a subject. In some aspects, the method comprises providing a subject suffering from liver I/R injury or at risk of suffering liver I/R injury; and administering to the subject one or more heparan sulfate (HS) compounds. In some aspects, the one or more HS compounds comprises about 5 to about 18 saccharide units, optionally about 12 to about 18 saccharide units. In some aspects, the one or more HS compounds comprises about 12 saccharide units. |
| FILED | Friday, May 13, 2022 |
| APPL NO | 17/744407 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/727 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/16 (20180101) A61P 7/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265730 | Danino et al. |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Tal Danino (Brooklyn, New York); Tiffany CHIEN (Arcadia, California); Tetsuhiro HARIMOTO (New York, New York) |
| ABSTRACT | The disclosure herein relates to engineered biosensor-containing bacteria, which is bacteria that contain at least one biosensor circuit, and uses thereof. A biosensor circuit can comprise an essential gene of the bacteria operably linked to an inducible promoter. Additionally, the bacteria can be engineered to be deficient in the endogenous copy of the at least one essential gene. |
| FILED | Thursday, May 05, 2022 |
| APPL NO | 17/737562 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) Original (OR) Class A61K 2035/11 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0008 (20130101) C12N 9/1096 (20130101) C12N 15/74 (20130101) C12N 2830/002 (20130101) Enzymes C12Y 102/01011 (20130101) C12Y 206/01016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265735 | Erdman |
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| APPLICANT(S) | Susan E. Erdman (Hopkinton, Massachusetts) |
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| INVENTOR(S) | Susan E. Erdman (Hopkinton, Massachusetts) |
| ABSTRACT | The inventions disclosed herein relate to the findings that L. reuteri bacteria isolated from dog saliva is capable of modulating a subject's body weight. In certain aspects, the inventions disclosed herein relate to the findings that L. reuteri species isolated from dog saliva elevates a subject's oxytocin levels in blood plasma and surprisingly, the killed (lysed) bacteria was sufficient to achieve the observed effects. |
| FILED | Wednesday, April 28, 2021 |
| APPL NO | 17/242635 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/747 (20130101) Original (OR) Class Peptides C07K 1/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265759 | MINSHALL et al. |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLIOIS (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard D. MINSHALL (Indian Head Park, Illinois); Zhenlong CHEN (Chicago, Illinois) |
| ABSTRACT | A novel peptide targeting CCR10-eNOS binding is provided as is a cell-permeable construct and method of using the construct to promote or accelerate wound healing, particularly diabetic wound healing. |
| FILED | Tuesday, July 28, 2020 |
| APPL NO | 17/628353 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 38/08 (20130101) Original (OR) Class A61K 47/64 (20170801) A61K 47/543 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265763 | Healy et al. |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
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| INVENTOR(S) | Kevin Edward Healy (Moraga, California); Samuel T. Wall (Osla, Norway); Krishanu Saha (Cambridge, Massachusetts); David V. Schaffer (Danville, California) |
| ABSTRACT | The present invention provides polypeptide-polymer conjugates. A subject polypeptide-polymer conjugate is useful in a variety of applications, which are also provided. |
| FILED | Tuesday, March 08, 2022 |
| APPL NO | 17/689631 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/1709 (20130101) Original (OR) Class A61K 47/58 (20170801) A61K 47/61 (20170801) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/22 (20130101) A61L 27/54 (20130101) A61L 31/16 (20130101) A61L 31/043 (20130101) Peptides C07K 14/47 (20130101) C07K 19/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265767 | Troy et al. |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Carol M. Troy (Hastings-on-Hudson, New York); Anna M. Potentski (New York, New York); Maria I. Avrutsky (Bronx, New York) |
| ABSTRACT | A method of providing a high concentration disulfide-linked caspase inhibitor-cell penetrating peptide conjugate is described. The method includes incubating a caspase inhibitor having one or more thiol groups with a reducing agent selected from dithiothreitol (DTT), 2-mercaptoethanol (2-ME) and tris(2-carboxyethyl)phosphine (TCEP) to provide a reduced caspase inhibitor, removing the reducing agent from the reduced caspase inhibitor, and conjugating the reduced caspase inhibitor with a cell-penetrating peptide by a disulfide linkage. |
| FILED | Wednesday, May 04, 2022 |
| APPL NO | 17/736946 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1761 (20130101) Original (OR) Class A61K 47/64 (20170801) Peptides C07K 1/1075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265775 | Rich et al. |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
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| INVENTOR(S) | Timothy P. Rich (Duluth, Minnesota); David H. Ingbar (Minneapolis, Minnesota) |
| ABSTRACT | A pharmaceutical composition for administering directly to the pulmonary tract of a subject includes an active agent effective to increase T3 concentration in the lung of the subject and a pharmaceutically acceptable buffer, adjusted to a pH of 5.5-8.5. The active agent can include a deiodinase inhibitor, a thyroid hormone mimetic, or a thyroid hormone analog. In some embodiments, the composition can include an additional active agent. The compositions can be used to treat lung inflammation. In some embodiments, the compositions also can be used to treat pulmonary edema. The compositions can be administered to a subject by direct instillation to the pulmonary tract or inhalation directly to the pulmonary tract. |
| FILED | Wednesday, July 29, 2020 |
| APPL NO | 17/628691 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0078 (20130101) A61K 31/17 (20130101) A61K 31/19 (20130101) A61K 31/138 (20130101) A61K 31/196 (20130101) A61K 31/343 (20130101) A61K 31/513 (20130101) A61K 31/573 (20130101) A61K 31/7076 (20130101) A61K 38/22 (20130101) Original (OR) Class A61K 38/28 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265779 | Mooney et al. |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David J. Mooney (Sudbury, Massachusetts); Cristina Borselli (Napoli, Italy); Herman H. Vandenburgh (Providence, Rhode Island); Eduardo Alexandre Barros E Silva (Davis, California); Lin Wang (Wuhan, China PRC); Dimitry Shvartsman (Belmont, Massachusetts); Hannah Storrie (Chapel Hill, North Carolina); Jeff Lichtman (Cambridge, Massachusetts) |
| ABSTRACT | An improved device and method for extended repair and regeneration of muscle tissue. An exemplary device comprises (a) a scaffold comprising an ECM component; (b) a combination of growth factors such as VEGF and IGF; and (c) a population of myogenic cells. Implantation of the device leads to muscle regeneration and repair over an extended period of time. |
| FILED | Tuesday, February 08, 2022 |
| APPL NO | 17/667189 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/19 (20130101) A61K 35/12 (20130101) A61K 35/34 (20130101) A61K 38/18 (20130101) A61K 38/30 (20130101) Original (OR) Class A61K 38/1866 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/20 (20130101) A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/3612 (20130101) A61L 27/3826 (20130101) A61L 27/3873 (20130101) A61L 2300/414 (20130101) A61L 2400/06 (20130101) A61L 2400/16 (20130101) A61L 2430/32 (20130101) Compositions of Macromolecular Compounds C08L 2201/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265791 | Hunt et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia); The University of Birmingham (Birmingham, United Kingdom); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, None); The University of Birmingham (Birmingham, United Kingdom); The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Donald F. Hunt (Charlottesville, Virginia); Jeffrey Shabanowitz (Charlottesville, Virginia); Keira Mahoney (Charlottesville, Virginia); Jennifer G. Abelin (Boston, Massachusetts); Mohammad Ovais Azizzanjani (Charlottesville, Virginia); Paisley Trantham Myers (Irmo, South Carolina); Stacy Alyse Malaker (Menlo Park, California); Andrew Norris (Oilville, Virginia); Jennifer Hitchcock (Charlottesville, Virginia); Xi Peng (Charlottesville, Virginia); Negin Ghafourian (Charlottesville, Virginia); Mark Cobbold (Winchester, Massachusetts); Sarah Penny (Birmingham, United Kingdom); Nico Buettner (Birmingham, United Kingdom); James M. Heather (Boston, Massachusetts) |
| ABSTRACT | Provided are compositions that include one or more synthetic target peptides, wherein each synthetic target peptide is about or at least 8-50 amino acids long; and has an amino acid sequence as set forth in Table 2 and/or Table 3. Also provided are in vitro populations of dendritic cells that include the disclosed compositions, in vitro population of CD8+ T cells capable of being activated upon being brought into contact with the disclosed populations of dendritic cells, antibodies or antibody-like molecules that specifically binds to a complex of an MHC class I molecule and a peptide having an amino acid sequence as set forth in Table 2 and/or Table 3, methods for treating and/or preventing cancers by administering a therapeutically effective dose of a composition that includes at least one target peptide having an amino acid sequence as set forth in Table 2 and/or Table 3. |
| FILED | Tuesday, July 21, 2020 |
| APPL NO | 17/629311 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/04 (20130101) A61K 38/1774 (20130101) A61K 39/0011 (20130101) Original (OR) Class A61K 47/6425 (20170801) A61K 2039/572 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265798 | Zhao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jean Zhao (Brookline, Massachusetts); Yunneng Tang (Brookline, Massachusetts); Xin Cheng (Brookline, Massachusetts) |
| ABSTRACT | The present invention is based, in part, on cancer vaccine compositions that comprise PTEN- and p53-deficient cancer cells with activated TGFβ-Smad/p63 signaling pathway, and methods for using same to prevent and/or treat cancer. |
| FILED | Tuesday, July 14, 2020 |
| APPL NO | 17/626263 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/001134 (20180801) Original (OR) Class A61K 2039/575 (20130101) A61K 2039/812 (20180801) A61K 2039/5156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265806 | Lai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Albert Einstein College of Medicine, Inc (Bronx, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan R. Lai (Dobbs Ferry, New York); Jose Quiroz (Bronx, New York); Ryan Malonis (Bronx, New York); Margaret Kielian (Dobbs Ferry, New York) |
| ABSTRACT | Provided are high affinity anti-alphavirus antibodies or alphavirus-binding fragments thereof, as well as methods of use and devices employing such antibodies and/or fragments. Further provided are complementarity determining region (CDR) sequences of variable domain light chain (VL) and variable domain heavy chain (VH) sequences, and the methods of using the high affinity anti-alphavirus antibodies for treating different types of alphavirus infections. |
| FILED | Thursday, June 06, 2019 |
| APPL NO | 16/972077 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/242 (20190101) A61K 39/12 (20130101) Original (OR) Class A61K 39/42 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/1081 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265809 | Balint et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Etubics Corporation (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph P. Balint (Seattle, Washington); Frank R. Jones (Seattle, Washington); Richard B. Gayle, III (Seattle, Washington) |
| ABSTRACT | Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided. |
| FILED | Wednesday, April 27, 2022 |
| APPL NO | 17/731106 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/191 (20130101) A61K 38/193 (20130101) A61K 38/204 (20130101) A61K 38/208 (20130101) A61K 38/217 (20130101) A61K 38/2013 (20130101) A61K 38/2026 (20130101) A61K 38/2033 (20130101) A61K 38/2046 (20130101) A61K 38/2066 (20130101) A61K 39/00 (20130101) A61K 39/0011 (20130101) A61K 39/12 (20130101) Original (OR) Class A61K 39/21 (20130101) A61K 39/235 (20130101) A61K 39/001106 (20180801) A61K 39/001182 (20180801) A61K 2039/54 (20130101) A61K 2039/57 (20130101) A61K 2039/545 (20130101) A61K 2039/575 (20130101) A61K 2039/5256 (20130101) A61K 2039/55555 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/005 (20130101) C07K 14/71 (20130101) C07K 14/70503 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2710/10034 (20130101) C12N 2710/10321 (20130101) C12N 2710/10334 (20130101) C12N 2710/10343 (20130101) C12N 2710/10371 (20130101) C12N 2710/20034 (20130101) C12N 2740/15034 (20130101) C12N 2740/16234 (20130101) C12N 2800/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265826 | Makale et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Milan T. Makale (San Diego, California); Wolfgang J. Wrasidlo (La Jolla, California); Santosh Kesari (La Jolla, California); Joanna McKittrick (La Jolla, California); Gustavo A. Hirata Flores (Ensenada, Mexico); Olivia Graeve (La Mesa, California) |
| ABSTRACT | There are provided, inter alia, compositions including a scintillator nanocrystal linked to a chemical agent moiety through a scintillator-activated photocleavable linker, and methods of use thereof. |
| FILED | Wednesday, December 29, 2021 |
| APPL NO | 17/564812 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 41/0042 (20130101) Original (OR) Class A61K 47/6923 (20170801) A61K 47/6929 (20170801) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/06 (20130101) A61N 5/10 (20130101) A61N 2005/0661 (20130101) A61N 2005/1098 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265832 | Serban |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MONTANA (Missoula, Montana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Monica Serban (Missoula, Montana) |
| ABSTRACT | The present disclosure provides compositions comprising a hydrolyzed tetraethyl orthosilicate (TEOS) and at least one macromolecule selected from the group consisting of hyaluronan and silk fibroin and methods of making thereof. The disclosure further provides methods of using the composition for delivery of an active agent and for treatment of diseases and disorders. Also provided are delivery devices and kits comprising the disclosed composition. |
| FILED | Thursday, June 25, 2020 |
| APPL NO | 17/637713 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 31/407 (20130101) A61K 31/496 (20130101) A61K 47/24 (20130101) A61K 47/34 (20130101) A61K 47/36 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265847 | HEYMACH et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | John V. HEYMACH (Houston, Texas); Monique NILSSON (Houston, Texas) |
| ABSTRACT | Aspects of the disclosure relate to a method for treating EGFR-mutant non-small-cell lung cancer (NSCLC) in a patient comprising administering a CD70 targeting molecule to the patient. Further aspects of the disclosure relate to a method for treating an epithelial-to-mesenchymal transition (EMT)-positive NSCLC in a patient comprising administering a CD70-targeting molecule to the patient. |
| FILED | Thursday, May 14, 2020 |
| APPL NO | 17/611019 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 45/06 (20130101) A61K 47/6857 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2875 (20130101) C07K 2317/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265852 | Brodsky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Harry Brodsky (Sudbury, Massachusetts); Neil Aronin (Newtonville, Massachusetts); Sarah Rinde Oikemus (Holden, Massachusetts) |
| ABSTRACT | The present invention contemplates allele-specific gene editing based on targeting a heterozygous single nucleotide polymorphism (SNP) in a protein coding sequence associated with a genetic disease. The data shown herein demonstrates that the outcome of such gene editing creates a nonesense mutation that results in a marked and selective reduction of mutant protein without affecting wild type protein expression. Expression of a single CRISPR-Cas9 nuclease in neurons generated a high frequency of mutations in the targeted HD allele that included both small insertion/deletion mutations and viral vector insertions. Thus, as disclosed herein, allele-specific targeting of InDel and insertion mutations to heterozygous coding SNPs provides a feasible approach to inactivate autosomal dominant mutations that cause genetic disease. |
| FILED | Wednesday, January 12, 2022 |
| APPL NO | 17/574163 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) Original (OR) Class A61K 48/0083 (20130101) A61K 48/0091 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265854 | Lim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Wendell A. Lim (San Francisco, California); Nicholas W. Frankel (San Francisco, California) |
| ABSTRACT | The present disclosure provides a genetically modified, in vitro immune cell. The immune cell is genetically modified with one or more nucleic acids comprising nucleotide sequences encoding: a) a chimeric polypeptide comprising: i) an antibody specific for a target antigen; and ii) a binding triggered transcriptional activator; and b) a cytokine or proliferation-inducing polypeptide that increases proliferation and/or activity of an effector immune cell, where the nucleotide sequence encoding the cytokine or proliferation-inducing polypeptide is operably linked to a transcriptional control element responsive to the transcriptional activator. The present disclosure provides compositions comprising the genetically modified, in vitro immune cell; and treatment methods comprising administration of the genetically modified, in vitro immune cell. |
| FILED | Tuesday, September 15, 2020 |
| APPL NO | 17/630875 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/15 (20130101) A61K 35/17 (20130101) A61K 48/005 (20130101) Original (OR) Class Peptides C07K 14/55 (20130101) C07K 14/705 (20130101) C07K 14/5418 (20130101) C07K 14/5443 (20130101) C07K 2317/622 (20130101) C07K 2319/03 (20130101) C07K 2319/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265863 | SANKARAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Vijay G. SANKARAN (ROSLINDALE, Massachusetts); Richard A. VOIT (WATERTOWN, Massachusetts); Leif S. LUDWIG (CAMBRIDGE, Massachusetts) |
| ABSTRACT | Described herein are methods and compositions related to GATA-1 gene therapy for the treatment of Diamond-Blackfan anemia. |
| FILED | Monday, June 08, 2020 |
| APPL NO | 17/612465 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) A61K 48/0066 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265864 | LYKENS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LifeSplice Pharma LLC (Malvern, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicole M. LYKENS (Malvern, Pennsylvania); Gordon J. LUTZ (Malvern, Pennsylvania); Melanie K. TALLENT (Malvern, Pennsylvania) |
| ABSTRACT | The invention provides splice modulating oligonucleotides (SMOs) designed to modulate the splicing of a RAGE pre-mRNA, compositions including the SMOs, and methods of treating and preventing diseases and conditions using the SMOs and compositions. |
| FILED | Thursday, August 15, 2019 |
| APPL NO | 17/635536 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0066 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265909 | Pentecost et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PHS Solutions LLC. (Ludlow Falls, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Randy J. Pentecost (Central City, Kentucky); Bryan S. Hall (Salyersville, Kentucky); Fred A. Sink (Ludlow Falls, Ohio) |
| ABSTRACT | An indirect drain flush system incorporating hot water to facilitate the transport of kidney dialysis effluent to wastewater treatment facilities is provided. Heated water is discharged into a waste line through an air gap, and the heated water increases the molecular interchange of fatty substances in the dialysis effluent, decreasing the viscosity of those fatty substances and preventing them from coagulating or crystalizing on pipes and drains. An air admittance valve may prevent negative pressure from building up within the system. |
| FILED | Friday, February 25, 2022 |
| APPL NO | 17/680604 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/1662 (20140204) Original (OR) Class A61M 1/1666 (20140204) A61M 2205/18 (20130101) A61M 2205/127 (20130101) A61M 2205/3337 (20130101) A61M 2205/3351 (20130101) A61M 2205/3355 (20130101) A61M 2205/7563 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220266006 | Jaroszeski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Douglas Walter Brown (Northumberland, Pennsylvania); University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark Jeffrey Jaroszeski (Wesley Chapel, Florida); Timothy Fawcett (Seffner, Florida); Richard Jason Connolly (Riverview, Florida); Andrew M. Hoff (Tampa, Florida); Reginald Morley Atkins (Riverview, Florida); Douglas Walter Brown (Sunbury, Pennsylvania); Richard A. Gilbert (Tampa, Florida) |
| ABSTRACT | The present invention provides a system and method for measuring the impedance of one more target cells before and after an electroporation protocol has been applied to the cells. The result of the impedance measurement provides a feedback control that can be implemented during and/or after the electroporation protocol to customize the electrical treatment for a particular target cell or cellular tissue. |
| FILED | Monday, May 02, 2022 |
| APPL NO | 17/734551 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/326 (20130101) Original (OR) Class A61N 1/327 (20130101) Apparatus for Enzymology or Microbiology; C12M 35/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220266014 | Moffitt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Boston Scientific Neuromodulation Corporation (Valencia, California); Augusta University Research Institute, Inc. (Augusta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael A. Moffitt (Solon, Ohio); David Blake (Martinez, Georgia) |
| ABSTRACT | A system for stimulation of a nucleus basalis of Meynert (NBM) of a patient includes an implantable electrical stimulation lead including electrodes and configured for implantation of at least one of the electrodes adjacent to or within the NBM of the patient; and an implantable pulse generator coupleable to the implantable electrical stimulation lead and configured for delivering electrical stimulation to the NBM through at least one of the electrodes of the implantable electrical stimulation lead, the implantable pulse generator including at least one processor configured to, upon user request, during an initial stimulation period, which is at least 1 month in duration and has a start and an end, increase over time at least one of a duration or an amplitude of the electrical stimulation from an initial value at the start of the initial stimulation period to a final value at the end of the initial stimulation period. |
| FILED | Thursday, February 24, 2022 |
| APPL NO | 17/680034 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0534 (20130101) A61N 1/3615 (20130101) Original (OR) Class A61N 1/36139 (20130101) A61N 1/36167 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267254 | Schoenberger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthias Schoenberger (Charlestown, Massachusetts); Jacob Hooker (Charlestown, Massachusetts) |
| ABSTRACT | Provided herein are radiolabeled compounds useful for minimally invasive imaging techniques. An exemplary radiolabeled compound provided herein is useful as a radiotracer for position emission tomography imaging of voltage gated sodium channels. Methods for prepared unlabeled and labeled compounds, and diagnostic methods using the compounds are also provided. |
| FILED | Thursday, August 05, 2021 |
| APPL NO | 17/395356 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/04 (20130101) Acyclic or Carbocyclic Compounds C07C 231/12 (20130101) Original (OR) Class C07C 237/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267258 | Krollenbrock et al. |
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| FUNDED BY |
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| APPLICANT(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS (WASHINGTON, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alina Krollenbrock (mILWAUKIE, Oregon); Michael K. Riscoe (Portland, Oregon) |
| ABSTRACT | Provided herein is a compound of Formula (I): wherein: R1 is selected from the group of —F, —Cl, —Br, —I, C1-C6 haloalkyl, C1-C6 haloalkoxy, —NO2, —C(H)═O, ═O, —CN, and COOR3; R2 is selected from the group of H and C1-C3 alkyl; and R3 is selected from the group of H, C1-C6 alkyl, and benzyl; or a pharmaceutically acceptable salt, co-crystal, ester, solvate, hydrate, isomer (including optical isomers, racemates, or other mixtures thereof), tautomer, isotope, polymorph, or pharmaceutically acceptable prodrug thereof, along with pharmaceutical compositions and methods of using the compound in the treatment of malaria, particularly including drug-resistant malaria. |
| FILED | Thursday, February 03, 2022 |
| APPL NO | 17/592366 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 33/06 (20180101) Acyclic or Carbocyclic Compounds C07C 281/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267274 | Jaffee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Elizabeth Jaffee (Baltimore, Maryland); Won Jin Ho (Ellicott City, Maryland) |
| ABSTRACT | Described are methods of treating solid cancers in a subject. The methods comprise the steps of administering to the subject having the solid cancer or prone of getting the solid cancer an antagonist of PTPN22, or the functional part of PTPN22, and treating the solid cancer. Methods comprising use of other anticancer agents and adjuvants in conjunction with PTPN22 inhibitors are also provided. |
| FILED | Friday, July 10, 2020 |
| APPL NO | 17/625976 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) A61K 31/713 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 215/56 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267275 | Rong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Chicago Biosolutions, Inc. (Chicago, Illinois); The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lijun Rong (Westmont, Illinois); Irina Gaisina (Berwyn, Illinois); Gregory R. Thatcher (Tucson, Arizona); Norton Peet (Chicago, Illinois) |
| ABSTRACT | Vaccination is the most prevalent prophylactic means for controlling seasonal influenza infections. However, an effective vaccine usually takes at least 6 months to develop for the circulating strains. Therefore, new therapeutic options are needed for acute treatment of influenza infections to control this virus and prevent epidemic/pandemic situations from developing. Described herein are fast-acting, orally active acylated amino-substituted heterocyclyl compounds effective to control this virus. In one aspect, described herein is a method of treating an influenza infection in a subject comprising administering to the subject the compounds described herein. |
| FILED | Tuesday, May 03, 2022 |
| APPL NO | 17/735235 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/16 (20180101) Heterocyclic Compounds C07D 215/58 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267283 | Andersen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of British Columbia (Vancouver, Canada); British Columbia Cancer Agency Branch (Vancouver, Canada) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Raymond John Andersen (Vancouver, Canada); Javier Garcia Fernandez (Colunga, Spain); Kunzhong Jian (Surrey, Canada); Marianne Dorothy Sadar (West Vancouver, Canada); Nasrin R. Mawji (Burnaby, Canada); Carmen Adriana Banuelos (Richmond, Canada) |
| ABSTRACT | Compounds having a structure of Formula I: or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R1, R2, R3, R11a, R11b, R11c, R11d, X, n1, n2, and n3 are as defined herein, are provided. Uses of such compounds for modulating androgen receptor activity, imaging diagnostics in cancer and therapeutics, and methods for treatment of subjects in need thereof, including prostate cancer are also provided. |
| FILED | Tuesday, April 26, 2022 |
| APPL NO | 17/729780 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4164 (20130101) A61K 31/4192 (20130101) A61K 31/5375 (20130101) A61K 45/06 (20130101) A61K 51/0453 (20130101) A61K 51/0459 (20130101) A61K 51/0463 (20130101) A61K 51/0465 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) General Methods of Organic Chemistry; Apparatus Therefor C07B 59/002 (20130101) Heterocyclic Compounds C07D 233/60 (20130101) C07D 249/04 (20130101) Original (OR) Class C07D 265/30 (20130101) C07D 295/084 (20130101) C07D 295/088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267303 | Palzkill et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Baylor College of Medicine (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Timothy Palzkill (Houston, Texas); Doris Taylor (Houston, Texas); Justin Anglin (Houston, Texas); Nicholas Simmons (Houston, Texas); John Faver (Houston, Texas); Yong Wang (Houston, Texas); Zhuang Jin (Houston, Texas) |
| ABSTRACT | The disclosure relates, in certain aspects, to compounds that can be used to inhibit β-lactamases, such as but not limited to OXA enzymes, such as but not limited to OXA-24, OXA-48, and/or OXA-58. In certain embodiments, these compounds can be used to inhibit activity of β-lactamases in vitro and in vivo. |
| FILED | Saturday, June 20, 2020 |
| APPL NO | 17/618017 |
| CURRENT CPC | Heterocyclic Compounds C07D 401/04 (20130101) C07D 401/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267312 | WALKER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Saint Louis University (St. Louis, Missouri); United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Saint Louis University (St. Louis, Missouri); United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | John K. WALKER (St. Louis, Missouri); Feng CAO (St. Louis, Missouri); Terri BOEHM (Ballwin, Missouri); Kinthada RAMAKUMAR (St. Louis, Missouri) |
| ABSTRACT | Provided herein are compounds of the formula: wherein the variables are as defined herein. Pharmaceutical compositions of the compounds are also provided. In some aspects, these compounds may be used for the treatment of diseases or disorders, such as an infection of an antibiotic resistant bacteria. |
| FILED | Wednesday, January 19, 2022 |
| APPL NO | 17/578616 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Heterocyclic Compounds C07D 417/04 (20130101) Original (OR) Class C07D 417/12 (20130101) C07D 417/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267362 | Montgomery et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John Montgomery (Ann Arbor, Michigan); Girish Chandra Sati (Ann Arbor, Michigan); Joshua Lane Martin (Ann Arbor, Michigan) |
| ABSTRACT | Provided herein are methods of glycosylation in the formation of disaccharides, trisaccharides, and oligosaccharides using fluoroglycosides, silyl ether glycosides and a triaryl borane catalyst. |
| FILED | Thursday, May 14, 2020 |
| APPL NO | 17/610996 |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/1804 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/00 (20130101) Original (OR) Class C07H 15/10 (20130101) C07H 15/18 (20130101) C07H 15/203 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267383 | Zolotukhin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida); The UAB Research Foundation (Birmingham, Alabama) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida); The UAB Research Foundation (Birmingham, Alabama) |
| INVENTOR(S) | Sergei Zolotukhin (Gainesville, Florida); Sanford L. Boye (Gainesville, Florida); Shannon E. Boye (Gainesville, Florida); Damien Marsic (Rockville, Maryland); Paul D. Gamlin (Birmingham, Alabama) |
| ABSTRACT | Adeno associated viral (AAV) particles are emerging as a useful vehicle for gene delivery to various organs and tissues, one of them being the retina. Provided here are variant AAV (e.g., variant serotype 2 (AAV2)) capsid proteins and variant capsid protein containing particles with enhanced ability to transduce retinal cells. |
| FILED | Tuesday, March 08, 2022 |
| APPL NO | 17/689324 |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 15/1037 (20130101) C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267390 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Reen Wu (Davis, California); Ching-Hsien Chen (Davis, California); David C. Yang (Davis, California) |
| ABSTRACT | This disclosure provides an isolated polypeptide therapeutics, polynucleotides encoding the polypeptides and antibodies that bind to the polypeptides are also provided. Therapeutic and diagnostic uses are further provided. |
| FILED | Friday, May 15, 2020 |
| APPL NO | 17/611511 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/496 (20130101) A61K 31/4418 (20130101) A61K 38/1709 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) Peptides C07K 14/4703 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14143 (20130101) C12N 2750/14171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267420 | SCHEINBERG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York); Eureka Therapeutics, Inc. (Emeryville, California) |
| ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York); Eureka Therapeutics, Inc. (Emeryville, California) |
| INVENTOR(S) | David A. SCHEINBERG (New York, New York); Cheng LIU (Emeryville, California); Zhiyuan YANG (Albany, California); Lianxing LIU (San Francisco, California); Shaohua Xu (San Francisco, California); Pei WANG (Albany, California); Yiyang XU (Pleasanton, California) |
| ABSTRACT | Provided herein are compositions, kits, and methods for manufacturing cells for adoptive cell therapy comprising (a) an engineered receptor, vector encoding an engineered receptor, or engineered immune cell expressing such engineered receptor or comprising such vector; and (b) a Fox P3 targeting agent. |
| FILED | Thursday, February 14, 2019 |
| APPL NO | 16/970332 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/7051 (20130101) C07K 14/70521 (20130101) C07K 14/70539 (20130101) C07K 16/18 (20130101) Original (OR) Class C07K 2317/31 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) C07K 2319/02 (20130101) C07K 2319/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267435 | LOHMUELLER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jason Jakob LOHMUELLER (Pittsburgh, Pennsylvania); Alexander DEITERS (Pittsburgh, Pennsylvania) |
| ABSTRACT | Disclosed are compositions and methods related to the construction and use of universal synthetic notch (synNotch) receptors and chimeric antigen receptor (CAR) T cells. |
| FILED | Thursday, October 03, 2019 |
| APPL NO | 17/282113 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 2039/5156 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/705 (20130101) C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 14/70578 (20130101) C07K 16/2803 (20130101) Original (OR) Class C07K 2319/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267439 | Jaiswal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Siddhartha Jaiswal (San Francisco, California); Irving L. Weissman (Stanford, California); Ravindra Majeti (Palo Alto, California); Mark P. Chao (Mountain View, California) |
| ABSTRACT | Methods are provided to manipulate phagocytosis of cells, including hematopoietic cells, e.g. circulating hematopoietic cells, bone marrow cells, acute leukemia cells, etc.; and solid tumor cells. In some embodiments of the invention the circulating cells are hematopoietic stem cells, or hematopoietic progenitor cells, particularly in a transplantation context, where protection from phagocytosis is desirable. In other embodiments the circulating cells are leukemia cells, particularly acute myeloid leukemia (AML), where increased phagocytosis is desirable. |
| FILED | Wednesday, May 04, 2022 |
| APPL NO | 17/736896 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39558 (20130101) A61K 47/6851 (20170801) A61K 47/6861 (20170801) A61K 47/6863 (20170801) A61K 47/6865 (20170801) A61K 47/6867 (20170801) A61K 47/6869 (20170801) A61K 2039/505 (20130101) Peptides C07K 16/18 (20130101) C07K 16/30 (20130101) C07K 16/2803 (20130101) Original (OR) Class C07K 16/2896 (20130101) C07K 16/3038 (20130101) C07K 16/3046 (20130101) C07K 16/3053 (20130101) C07K 16/3061 (20130101) C07K 16/3069 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267720 | O'NEILL et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Xylyx Bio, Inc. (Brooklyn, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John O'NEILL (New York, New York); Igal GERMANGUZ (Brooklyn, New York); Evelyn ARANDA (Astoria, New York); Jennifer XIONG (New York, New York); Natalia KISSEL (Brooklyn, New York); Alexandra NICHOLS (Brooklyn, New York) |
| ABSTRACT | An in vitro cell culture substrate is disclosed. The substrate comprises a decellularized tissue-specific extracellular matrix, wherein the tissue-specific extracellular matrix is derived from fibrotic tissue. A method of method of assessing an in vitro fibrotic cell culture is also disclosed. The method comprises providing one or more substrates comprising decellularized tissue-specific extracellular matrix derived from fibrotic tissue, where each substrate is provided in segregated manner. The method further comprises culturing native cells in each substrate to form a fibrotic cell culture. The method further comprises assessing at least one characteristic of each fibrotic cell culture. |
| FILED | Thursday, July 23, 2020 |
| APPL NO | 17/629046 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) Original (OR) Class C12N 2500/84 (20130101) C12N 2501/11 (20130101) C12N 2501/115 (20130101) C12N 2533/90 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5082 (20130101) G01N 2800/085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267740 | Schmitt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anthony Paul Schmitt (State College, Pennsylvania); Phuong Tieu Schmitt (State College, Pennsylvania); Greeshma Vivekananda Ray (Cleveland, Ohio) |
| ABSTRACT | Provided are modified virus-like particles (VLPs) of paramyxoviruses, compositions containing them, methods of using the VLPs for delivery of any particular protein of interest to any of a variety of cells, kits that contain expression vectors for making, using and detecting VLPs, and methods for screening for anti-viral compounds using the VLPs. The modified VLPs contain a contiguous recombinant polypeptide that contains i) all or a segment of a C-terminal domain of a paramyxovirus nucleocapsid protein and ii) a polypeptide sequence of a distinct protein. Non-covalent complexes of paramyxovirus M protein and fusion proteins that contain a C-terminal domain of a paramyxovirus nucleocapsid protein and a polypeptide sequence of a distinct protein are provided, as are non-covalent complexes of cells, and cell receptors, with modified VLPs. |
| FILED | Monday, April 18, 2022 |
| APPL NO | 17/723054 |
| CURRENT CPC | Peptides C07K 14/005 (20130101) C07K 14/8121 (20130101) C07K 16/1027 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 9/0069 (20130101) C12N 9/0089 (20130101) C12N 2760/18022 (20130101) C12N 2760/18023 (20130101) C12N 2760/18034 (20130101) C12N 2760/18222 (20130101) C12N 2760/18223 (20130101) C12N 2760/18234 (20130101) C12N 2760/18252 (20130101) C12N 2760/18722 (20130101) C12N 2760/18723 (20130101) C12N 2760/18734 (20130101) Enzymes C12Y 113/12005 (20130101) C12Y 115/01001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267759 | Sanjana et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | New York Genome Center, Inc. (New York, New York); New York University (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Neville E. Sanjana (New York, New York); Antonino Montalbano (New York, New York); Noa Liscovitch-Brauer (Brooklyn, New York) |
| ABSTRACT | An in vitro method is provided for analyzing chromatin accessibility and screening RNA of each single cell in a heterologous population (e.g., a library of cells). The method comprises incubating cell nuclei obtained from lysed cells with a transposome complex in a tagmentation buffer, performing reverse transcription wherein each of the RNAs is reverse transcribed to a DNA barcoded with the first barcode; sequencing DNA, which is extracted from digested cell nuclei; and analyzing chromatin accessibility and RNA of the cells. In a further embodiment, the method described comprises performing combinatorial cellular indexing and/or a perturbation step. Additionally, provided are a transposase TnY, buffer(s), and kit(s) for use in the described method. |
| FILED | Sunday, July 12, 2020 |
| APPL NO | 17/626598 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 15/907 (20130101) C12N 15/1065 (20130101) Original (OR) Class C12N 2310/20 (20170501) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267808 | Doudna et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Emmanuelle Charpentier (Berlin, Germany); The Regents of the University of California (Oakland, California); University of Vienna (Vienna, Austria) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jennifer A. Doudna (Berkeley, California); Martin Jinek (Berkeley, California); Krzysztof Chylinski (Vienna, Austria); Emmanuelle Charpentier (Berlin, Germany) |
| ABSTRACT | The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a polypeptide associated with the target DNA. The present disclosure further provides site-specific modifying polypeptides. The present disclosure further provides methods of site-specific modification of a target DNA and/or a polypeptide associated with the target DNA The present disclosure provides methods of modulating transcription of a target nucleic acid in a target cell, generally involving contacting the target nucleic acid with an enzymatically inactive Cas9 polypeptide and a DNA-targeting RNA. Kits and compositions for carrying out the methods are also provided. The present disclosure provides genetically modified cells that produce Cas9; and Cas9 transgenic non-human multicellular organisms. |
| FILED | Thursday, March 24, 2022 |
| APPL NO | 17/703845 |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 6/4684 (20180501) Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/027 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/465 (20130101) A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/63 (20130101) C12N 15/70 (20130101) C12N 15/90 (20130101) C12N 15/102 (20130101) C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 15/746 (20130101) C12N 15/902 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/13 (20130101) C12N 2310/20 (20170501) C12N 2310/531 (20130101) C12N 2310/3519 (20130101) C12N 2800/80 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Enzymes C12Y 301/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267827 | Nolan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Garry P. Nolan (Redwood City, California); Nikolay Samusik (Mountain View, California); Julia Kennedy-Darling (STANFORD, California); Yury Goltsev (STANFORD, California) |
| ABSTRACT | Provided herein is a method and system for analyzing a sample. In some embodiments the method makes use of a plurality of capture agents that are each linked to a different oligonucleotide and a corresponding plurality of labeled nucleic acid probes, wherein each of the labeled nucleic acid probes specifically hybridizes with only one of the oligonucleotides. The sample is labeled with the capture agents en masse, and sub-sets of the capture agents are detected using iterative cycles using corresponding subsets of the labeled nucleic acid probes. |
| FILED | Monday, October 11, 2021 |
| APPL NO | 17/498627 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6804 (20130101) Original (OR) Class C12Q 1/6813 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) G01N 33/554 (20130101) G01N 33/5308 (20130101) G01N 33/54306 (20130101) G01N 2001/302 (20130101) G01N 2458/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267839 | Disney |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew D. Disney (Jupiter, Florida) |
| ABSTRACT | The invention is directed to a method of identifying the interactions of RNA such as miRNA with small molecules interacting with RNA (SMIRNAs). A candidate SMIRNA group is associated with a photoaffinity diazirene group that can form a covalent complex with an RNA target site and with an alkyne group that can be used in subsequent “click chemistry’ reactions such as a “CuAAC” reaction, a copper-catalyzed alkyne-azide cy-cloaddition to yield a stable triazole ring. By this means, the RNA binding site of the small molecule can be identified via isolation of the RNA-targetSMIRNA covalent complex and reverse transcription of the RNA followed by DNA sequencing of the reverse transcription product. Sites on the RNA blocked during reverse transcription by the covalently bound SMIRNA are identified as terminations in the sequence compared to the native RNA. |
| FILED | Wednesday, June 24, 2020 |
| APPL NO | 17/622005 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267848 | ZHANG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | David ZHANG (Houston, Texas); Juexiao WANG (Houston, Texas) |
| ABSTRACT | This disclosure describes methods for enabling accurate detection and quantitation of rare alleles within a DNA sample using low-depth sequencing, through the use of allele-specific enrichment and/or depletion hybridization probes. For example, methods are provided for using competitive probes to apply allele-specific enrichment or depletion to amplicons from multiplex PCR on a biological DNA sample. |
| FILED | Monday, May 02, 2022 |
| APPL NO | 17/735062 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) C12Q 1/6876 (20130101) Original (OR) Class C12Q 1/6886 (20130101) C12Q 2600/16 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267851 | Dai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Qi Dai (Nashville, Tennessee); Chang Yu (Nashville, Tennessee); Martha Shrubsole (Nashville, Tennessee); Xiangzhu Zhu (Nashville, Tennessee); Douglas Seidner (Nashville, Tennessee) |
| ABSTRACT | The presently-disclosed subject matter includes methods for detecting methylation biomarkers in a biological sample from a subject in need of assessment for magnesium deficiency status, methods of diagnosing magnesium deficiency, methods of diagnosing magnesium insufficiency, methods of treating magnesium deficiency, methods of diagnosing magnesium insufficiency, and methods of preventing or reducing a risk of developing a condition linked to magnesium deficiency. |
| FILED | Wednesday, June 24, 2020 |
| APPL NO | 17/621996 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/154 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267928 | Doudna et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Emmanuelle Charpentier (Berlin, Germany); The Regents of the University of California (Oakland, California); University of Vienna (Vienna, Austria) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jennifer A. Doudna (Berkeley, California); Martin Jinek (Berkeley, California); Krzysztof Chylinski (Vienna, Austria); Emmanuelle Charpentier (Berlin, Germany) |
| ABSTRACT | The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a polypeptide associated with the target DNA. The present disclosure further provides site-specific modifying polypeptides. The present disclosure further provides methods of site-specific modification of a target DNA and/or a polypeptide associated with the target DNA The present disclosure provides methods of modulating transcription of a target nucleic acid in a target cell, generally involving contacting the target nucleic acid with an enzymatically inactive Cas9 polypeptide and a DNA-targeting RNA. Kits and compositions for carrying out the methods are also provided. The present disclosure provides genetically modified cells that produce Cas9; and Cas9 transgenic non-human multicellular organisms. |
| FILED | Thursday, March 24, 2022 |
| APPL NO | 17/703849 |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/02 (20130101) C30B 29/38 (20130101) C30B 29/406 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/205 (20130101) H01L 33/32 (20130101) H01L 33/0075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220268785 | Shi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois); Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tujin Shi (Richland, Washington); Huiping Liu (Chicago, Illinois); Chia-Feng Tsai (West Richland, Washington); David Scholten (Chicago, Illinois); Reta Birhanu Kitata (Richland, Washington); Carolina Reduzzi (Evanston, Illinois) |
| ABSTRACT | Disclosed are compositions and methods for performing a proteomic analysis. Particularly disclosed are compositions and methods for preparing a sample for quantitative single-cell proteomics. |
| FILED | Monday, February 21, 2022 |
| APPL NO | 17/651896 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6848 (20130101) Original (OR) Class G01N 2440/00 (20130101) G01N 2560/00 (20130101) G01N 2570/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220268786 | MITSUYA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE (Tokyo, Japan); NATIONAL CANCER CENTER (Tokyo, Japan); SYSMEX CORPORATION (Kobe-shi, Japan) |
| ASSIGNEE(S) | NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE (Tokyo, Japan); NATIONAL CANCER CENTER (Tokyo, Japan); SYSMEX CORPORATION (Kobe-shi, Japan) |
| INVENTOR(S) | Hiroaki MITSUYA (Tokyo, Japan); Kenji MAEDA (Tokyo, Japan); Akinobu HAMADA (Tokyo, Japan); Kenta NODA (Kobe-shi, Japan); Kazuto YAMASHITA (Kobe-shi, Japan); Yusuke ATARASHI (Kobe-shi, Japan); Nobuyuki IDE (Kobe-shi, Japan) |
| ABSTRACT | Disclosed is a method for acquiring information on exacerbation risk of COVID-19, comprising measuring IgM antibody against S antigen of SARS-CoV-2 contained in a specimen collected from a subject infected with SARS-CoV-2 or a subject suspected of suffering from COVID-19, wherein a value obtained by the measurement of IgM antibody serves as an index of exacerbation risk of COVID-19 of the subject. |
| FILED | Friday, February 18, 2022 |
| APPL NO | 17/675418 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6854 (20130101) Original (OR) Class G01N 2469/20 (20130101) G01N 2800/26 (20130101) G01N 2800/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220268788 | Martinez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Briana Martinez (Tempe, Arizona); Sarah Stabenfeldt (Tempe, Arizona); Chris Diehnelt (Chandler, Arizona); Nicholas Stephanopoulos (Scottsdale, Arizona); Crystal Willingham (Tempe, Arizona); Amanda Witten (Phoenix, Arizona); Kendall Lundgreen (Gilbert, Arizona) |
| ABSTRACT | A unique pipeline is employed for biomarker discovery that entailed domain antibody phage display, next generation sequencing analysis, and nanotechnology strategies to generate antibody mimetics are disclosed. Also disclosed are the temporal biomarkers of traumatic brain injury and their methods of use. In some embodiments, the temporal biomarkers are synthetic peptides comprising the HCDR3 sequences identified using the disclosed pipeline. In some aspects, the synthetic peptides have less than 30 amino acid residues and comprise a biotin scaffold that is linked to the HCDR3 sequences. |
| FILED | Friday, June 19, 2020 |
| APPL NO | 17/620088 |
| CURRENT CPC | Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) Original (OR) Class G01N 2800/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220270244 | Chuang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jeffrey Hsu-Min Chuang (West Hartford, Connecticut); Javad Noorbakhsh (Cambridge, Massachusetts); Ali Foroughi pour (Bristol, Connecticut); Kourosh Zarringhalam (Arlington, Massachusetts); Saman Farahmand (Quincy, Massachusetts); Mohammad Soltanieh-ha (Cambridge, Massachusetts); The Jackson Laboratory (Bar Harbor, Maine) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeffrey Hsu-Min Chuang (West Harford, Connecticut); Javad Noorbakhsh (Cambridge, Massachusetts); Ali Foroughi pour (Bristol, Connecticut); Kourosh Zarringhalam (Arlington, Massachusetts); Saman Farahmand (Quincy, Massachusetts); Mohammad Soltanieh-ha (Cambridge, Massachusetts) |
| ABSTRACT | Techniques for classifying, using a deep learning model, histopathological whole slide images (WSIs) as comprising images of cancerous or non-cancerous tissue and/or as comprising images of cancerous tissue having a genetic mutation or not having a genetic mutation are described herein. The techniques include at least one processor configured to instantiate a container-based processing architecture to train and/or use the deep learning model to process and classify at least one WSI. In some embodiments, a treatment may be selected and administered based on a classification result obtained from the deep learning model. |
| FILED | Friday, July 17, 2020 |
| APPL NO | 17/628144 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/4833 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/063 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 7/194 (20170101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30024 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220270259 | Yan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hengtao Guo (Troy, New York); RENSSELAER POLYTECHNIC INSTITUTE (Clifton Park, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Pingkun Yan (Clifton Park, New York); Hengtao Guo (Troy, New York) |
| ABSTRACT | A method of ultrasound image volume reconstruction includes: providing a convolutional neural network (“CNN”); receiving a first dataset comprising at least one pair of consecutive ultrasound images; inputting the first dataset to the CNN; training the CNN with the first dataset; receiving a second dataset comprising an ultrasound video comprising a plurality of consecutive ultrasound images; inputting the second dataset to the CNN; and processing, by the CNN, the second dataset to produce as output a reconstructed 3D ultrasound image volume. |
| FILED | Wednesday, December 22, 2021 |
| APPL NO | 17/558869 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/44 (20130101) Image Data Processing or Generation, in General G06T 7/0016 (20130101) Original (OR) Class G06T 2207/10136 (20130101) Image or Video Recognition or Understanding G06V 10/36 (20220101) G06V 10/82 (20220101) G06V 10/454 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220270357 | Goyal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Diksha Goyal (Tempe, Arizona); Jianming Liang (Scottsdale, Arizona) |
| ABSTRACT | Described herein are means for implementing medical image segmentation using interactive refinement, in which the trained deep models are then utilized for the processing of medical imaging. For instance, an exemplary system is specially configured for operating a two-step deep learning training framework including means for receiving original input images at the deep learning training framework; means for generating an initial prediction image specifying image segmentation by processing the original input images through the base segmentation model to render the initial prediction image in the absence of user input guidance signals; means for receiving user input guidance signals indicating user-guided segmentation refinements to the initial prediction image; means for routing each of (i) the original input images, (ii) the initial prediction image, and (iii) the user input guidance signals to an InterCNN; means for generating a refined prediction image specifying refined image segmentation by processing each of the (i) the original input images, (ii) the initial prediction image, and (iii) the user input guidance signals through the InterCNN to render the refined prediction image incorporating the user input guidance signals; and means for outputting a refined segmentation mask based on application of the user input guidance signals to the deep learning training framework as a guidance signal. Other related embodiments are disclosed. |
| FILED | Friday, February 18, 2022 |
| APPL NO | 17/675929 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) G06T 7/194 (20170101) G06T 2200/24 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/20092 (20130101) G06T 2207/30004 (20130101) Image or Video Recognition or Understanding G06V 10/82 (20220101) G06V 10/7747 (20220101) G06V 10/7788 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20220264965 | REDMOND et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vorbeck Materials Corp. (Jessup, Maryland) |
| ASSIGNEE(S) | Vorbeck Materials Corp. (Jessup, Maryland) |
| INVENTOR(S) | KATE REDMOND (BALTIMORE, Maryland); DAN SCHEFFER (FREDERICK, Maryland); SRIRAM MANIVANNAN (BALTIMORE, Maryland); KEREN ESPINA (RANDALLSTOWN, Maryland); ETHAN TAUB (JESSUP, Maryland); JODY KUO (JESSUP, Maryland); JOHN S LETTOW (WASHINGTON, District of Columbia) |
| ABSTRACT | The present invention relates generally to transmission lines and specifically to textile transmission line assemblies. The textile transmission line assemblies are capable of lateral bending, axial rotation, and stretching without suffering from a statistically significant loss of its performance characteristics. Antenna elements are incorporated with the textile transmission line assemblies (hereinafter “combination assemblies”). The textile transmission line assemblies can be incorporated in to garments, apparel items, bags, tents, or other textile-based objects. The textile transmission line assemblies are configured to be flexibly affixed to textile items. The textile transmission line assemblies are impact resistant. Wearable communications systems that incorporate at least one textile transmission line assembly and/or combination assembly are also disclosed. |
| FILED | Wednesday, February 23, 2022 |
| APPL NO | 17/679070 |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 1/002 (20130101) Original (OR) Class Antennas, i.e Radio Aerials H01Q 1/273 (20130101) Transmission H04B 13/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265188 | Faughn |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Army Combat Capabilities Development Command, Army Research Labortory (Adelphi, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jim A. Faughn (Glen Arm, Maryland) |
| ABSTRACT | Various embodiments are directed to systems, apparatus and methods configured for anthropometrics data/measurement acquisition such as for fitment of handguns, hand tools, weapons and the like. |
| FILED | Monday, February 22, 2021 |
| APPL NO | 17/180900 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/225 (20130101) Original (OR) Class A61B 5/702 (20130101) A61B 5/1072 (20130101) Smallarms, e.g Pistols, Rifles; Accessories Therefor F41C 27/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265234 | Maidment et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew D.A. Maidment (Villanova, Pennsylvania); Anatoliy V. Popov (Philadelphia, Pennsylvania); E James Delikatny (Havertown, Pennsylvania); Andrew Tsourkas (Bryn Mawr, Pennsylvania); Roshan Karunamuni (Philadelphia, Pennsylvania); Ajlan Al Zaki (Philadelphia, Pennsylvania); Sara Gavenonis (Wilmington, Delaware); fDavid Cormode (Philadelphia, Pennsylvania) |
| ABSTRACT | Contrast agents for x-ray imaging including stabilized metal nanoparticles and encapsulated nanoparticles, as well as methods for imaging tissue with these agents, are disclosed. Also disclosed are methods of dual energy x-ray imaging using metal nanoparticle contrast agents or encapsulated metal nanoparticles. |
| FILED | Friday, April 01, 2022 |
| APPL NO | 17/711156 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/481 (20130101) Original (OR) Class A61B 6/482 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 47/02 (20130101) A61K 47/10 (20130101) A61K 47/32 (20130101) A61K 49/04 (20130101) A61K 49/0423 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265281 | KOSIOREK et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ALPHAPOINTE (Kansas City, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | CHRISTOPHER B. KOSIOREK (LA VERNIA, Texas); RYAN WILLIAMS (OLATHE, Kansas); ESRA ABIR (NEW YORK, New York); BRENDA MEE (WEST NEWFIELD, Maine); DEXTER C. DRAYTON (SAN ANTONIO, Texas); NESLIHAN DAMAR (KUCUKYALI, Turkey); NILUFER POLAT (BROOKLYN, New York); YAVUZ AVCI (SUNNYSIDE, New York) |
| ABSTRACT | A pre-fabricated tourniquet that is easy to apply, that ensures consistent and even circumferential pressure, that is lightweight, that provides standard life saving operation, and that can be utilized in any setting or situation, and related methods are provided. Mechanically constricting tourniquet apparatus and related methods are provided that are comprised of a tourniquet body, a carriage, a torsion bar, a receiver, and a slider. The tourniquet is long enough to encircle a human limb, for example, an arm or leg. The tourniquet apparatus includes several features for preventing or otherwise limiting harm to users and/or damage to the tourniquet apparatus itself. |
| FILED | Monday, May 09, 2022 |
| APPL NO | 17/740082 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/135 (20130101) Original (OR) Class A61B 17/1327 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49826 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265660 | Zuo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ting Therapeutics LLC (Omaha, Nebraska) |
| ASSIGNEE(S) | Ting Therapeutics LLC (Omaha, Nebraska) |
| INVENTOR(S) | Jian Zuo (Omaha, Nebraska); Tal Teitz (Omaha, Nebraska) |
| ABSTRACT | Method, kit and pharmaceutical compositions using an inhibitor of EGFR signaling for prevention or treatment of hearing loss are described. |
| FILED | Wednesday, May 04, 2022 |
| APPL NO | 17/736330 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) A61K 31/506 (20130101) A61K 31/519 (20130101) Original (OR) Class A61K 31/4439 (20130101) A61K 31/4709 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/16 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265700 | Seol et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dong Rim Seol (Iowa City, Iowa); James A. Martin (Iowa City, Iowa); Tae-Hong Lim (Coralville, Iowa); Mitchell C. Coleman (Iowa City, Iowa); Aliasger K. Salem (Coralville, Iowa); Ino Song (Iowa City, Iowa) |
| ABSTRACT | A method to prevent, inhibit or treat intervertebral disc disease in a mammal and compositions useful in that regard are provided. |
| FILED | Thursday, January 20, 2022 |
| APPL NO | 17/580129 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0019 (20130101) A61K 31/155 (20130101) A61K 31/515 (20130101) A61K 31/728 (20130101) Original (OR) Class A61K 31/7076 (20130101) A61K 47/34 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265730 | Danino et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Tal Danino (Brooklyn, New York); Tiffany CHIEN (Arcadia, California); Tetsuhiro HARIMOTO (New York, New York) |
| ABSTRACT | The disclosure herein relates to engineered biosensor-containing bacteria, which is bacteria that contain at least one biosensor circuit, and uses thereof. A biosensor circuit can comprise an essential gene of the bacteria operably linked to an inducible promoter. Additionally, the bacteria can be engineered to be deficient in the endogenous copy of the at least one essential gene. |
| FILED | Thursday, May 05, 2022 |
| APPL NO | 17/737562 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) Original (OR) Class A61K 2035/11 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0008 (20130101) C12N 9/1096 (20130101) C12N 15/74 (20130101) C12N 2830/002 (20130101) Enzymes C12Y 102/01011 (20130101) C12Y 206/01016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265833 | SHUKLA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anita SHUKLA (Providence, Rhode Island); Noel VERA-GONZALEZ (San Juan, Puerto Rico) |
| ABSTRACT | The present invention relates generally to antifungal hydrogels to locally deliver antifungal drugs. Specifically, the present invention provides aspartic protease-triggered antifungal hydrogels to locally deliver antifungal drugs that specifically respond to aspartic proteases secreted by virulent, pathogenic Candida. |
| FILED | Monday, February 28, 2022 |
| APPL NO | 17/682782 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/5026 (20130101) A61K 31/7048 (20130101) A61K 38/12 (20130101) A61K 47/32 (20130101) A61K 47/42 (20130101) Original (OR) Class A61K 47/60 (20170801) A61K 47/65 (20170801) A61K 47/6903 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265867 | Bates et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paula J. Bates (Louisville, Kentucky); Mohammad Tariq Malik (Prospect, Kentucky); Kyung A. Kang (Louisville, Kentucky) |
| ABSTRACT | A composition comprises an anti-nucleolin agent conjugated to nanoparticles. The nanoparticles are non-magnetic, not iron oxide and not polyacrylamide. Furthermore, a pharmaceutical composition for treating cancer comprises a composition including an anti-nucleolin agent conjugated to nanoparticles, and a pharmaceutically acceptable carrier. |
| FILED | Wednesday, May 11, 2022 |
| APPL NO | 17/741686 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/61 (20170801) A61K 47/62 (20170801) A61K 47/6923 (20170801) A61K 47/6929 (20170801) A61K 49/04 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265929 | Gholami |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Autonomous Healthcare, Inc. (Hoboken, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Behnood Gholami (Hoboken, New Jersey) |
| ABSTRACT | The present disclosure describes a closed-loop fluid resuscitation and/or cardiovascular drug administration system that uses continuous measurements and adaptive control architecture. The adaptive control architecture uses a function approximator to identify unknown dynamics and physiological parameters of a patient to compute appropriate infusion rates and to regulate the endpoint of resuscitation. |
| FILED | Thursday, April 28, 2022 |
| APPL NO | 17/731347 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/1723 (20130101) Original (OR) Class A61M 2205/50 (20130101) A61M 2205/52 (20130101) A61M 2205/502 (20130101) A61M 2205/3569 (20130101) A61M 2230/00 (20130101) A61M 2230/06 (20130101) A61M 2230/30 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 20/17 (20180101) G16H 40/63 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220266532 | Kenderian et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Shant Kenderian (Pasadena, California); Joseph T. Case (Hawthorne, California) |
| ABSTRACT | A build plate may include one or more thermocouples placed on an underside of the build plate. The one or more thermocouples output temperature fluctuation to assist in monitoring for build plate separation of a product located on top of the build plate. |
| FILED | Friday, May 13, 2022 |
| APPL NO | 17/743841 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/245 (20170801) B29C 64/393 (20170801) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220266997 | Bennett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | TEXTRON INNOVATIONS INC. (Providence, Rhode Island) |
| ASSIGNEE(S) | TEXTRON INNOVATIONS INC. (Providence, Rhode Island) |
| INVENTOR(S) | Evan Butler Bennett (Fort Worth, Texas); George Ryan Decker (Loveland, Colorado); Thomas Earl Johnson (Dallas, Texas) |
| ABSTRACT | Embodiments are directed to a tiltrotor aircraft having a wing, a proprotor pivotably mounted on the wing, and a downstop striker attached to the proprotor using a load pin, wherein the load pin is configured to generate an output signal representing a force between the proprotor and the wing. A downstop mounted on the wing is aligned to be in contact with the downstop striker when the proprotor is in a horizontal position. A conversion actuator moves the proprotor between a horizontal position and vertical position. A flight control computer is coupled to the output signal from the load pin and configured to control the conversion actuator, wherein the flight control computer is configured to cause the conversion actuator to increase the force if the force is less than a first selected preload value or to decrease the force if the force is greater than a second selected preload value. |
| FILED | Wednesday, February 24, 2021 |
| APPL NO | 17/183510 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 19/00 (20130101) B64C 29/0033 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267025 | Augustyn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Textron Innovations Inc. (Fort Worth, Texas) |
| ASSIGNEE(S) | Textron Innovations Inc. (Fort Worth, Texas) |
| INVENTOR(S) | Jacob Eugene Augustyn (Grapevine, Texas); Evan Butler Bennett (Greenfield, Wisconsin); Charles Eric Covington (Colleyville, Texas); Thomas Earl Johnson, JR. (Dallas, Texas) |
| ABSTRACT | A pylon tracking system for a tiltrotor aircraft including first and second pylons each having a pylon conversion actuator with primary and backup drive systems. The pylon tracking system includes a plurality of rotary position sensors including a first rotary position sensor coupled to the primary drive system of the first pylon, a second rotary position sensor coupled to the backup drive system of the first pylon, a third rotary position sensor coupled to the primary drive system of the second pylon and a fourth rotary position sensor coupled to the backup drive system of the second pylon. A flight control computer is in communication with the plurality of rotary position sensors and is configured to process feedback therefrom to identify a differential pylon angle between the first and second pylons during pylon conversion operations. |
| FILED | Friday, December 03, 2021 |
| APPL NO | 17/541906 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 13/38 (20130101) B64C 29/0033 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/26 (20130101) B64D 45/0005 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267153 | Tour et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William Marsh Rice University (Houston, Texas); B.G. Negev Technologies and Applications Ltd. at Ben-Gurion University (Beer Sheva, Israel) |
| ASSIGNEE(S) | WILLIAM MARSH RICE UNIVERSITY (Houston, Texas); B.G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD. AT BEN-GURION UNIVERSITY (Beer Sheva, Israel) |
| INVENTOR(S) | James M. Tour (Bellaire, Texas); Yieu Chyan (Houston, Texas); Christopher John Arnusch (Midreshet Ben-Gurion, Israel); Swatantra Pratap Singh (Midreshet Ben-Gurion, Israel); Yilun Li (Sugar Land, Texas); Duy X. Luong (Houston, Texas); Carter Kittrell (Houston, Texas); Ruquan Ye (Houston, Texas); Jordan Miller (Houston, Texas); Ian Kinstlinger (Houston, Texas); Savannah Cofer (Gahanna, Ohio) |
| ABSTRACT | Methods that expand the properties of laser-induced graphene (LIG) and the resulting LIG having the expanded properties. Methods of fabricating laser-induced graphene from materials, which range from natural, renewable precursors (such as cloth or paper) to high performance polymers (like Kevlar). With multiple lasing, however, highly conductive PEI-based LIG could be obtained using both multiple pass and defocus methods. The resulting laser-induced graphene can be used, inter alia, in electronic devices, as antifouling surfaces, in water treatment technology, in membranes, and in electronics on paper and food Such methods include fabrication of LIG in controlled atmospheres, such that, for example, superhydrophobic and superhydrophilic LIG surfaces can be obtained. Such methods further include fabricating laser-induced graphene by multiple lasing of carbon precursors. Such methods further include direct 3D printing of graphene materials from carbon precurors. Application of such LIG include oil/water separation, liquid or gas separations using polymer membranes, anti-icing, microsupercapacitors, supercapacitors, water splitting catalysts, sensors, and flexible electronics. |
| FILED | Monday, November 01, 2021 |
| APPL NO | 17/516430 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/184 (20170801) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/01 (20130101) C01P 2002/82 (20130101) C01P 2004/03 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/005 (20130101) H01S 3/0007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267258 | Krollenbrock et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS (WASHINGTON, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alina Krollenbrock (mILWAUKIE, Oregon); Michael K. Riscoe (Portland, Oregon) |
| ABSTRACT | Provided herein is a compound of Formula (I): wherein: R1 is selected from the group of —F, —Cl, —Br, —I, C1-C6 haloalkyl, C1-C6 haloalkoxy, —NO2, —C(H)═O, ═O, —CN, and COOR3; R2 is selected from the group of H and C1-C3 alkyl; and R3 is selected from the group of H, C1-C6 alkyl, and benzyl; or a pharmaceutically acceptable salt, co-crystal, ester, solvate, hydrate, isomer (including optical isomers, racemates, or other mixtures thereof), tautomer, isotope, polymorph, or pharmaceutically acceptable prodrug thereof, along with pharmaceutical compositions and methods of using the compound in the treatment of malaria, particularly including drug-resistant malaria. |
| FILED | Thursday, February 03, 2022 |
| APPL NO | 17/592366 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 33/06 (20180101) Acyclic or Carbocyclic Compounds C07C 281/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267435 | LOHMUELLER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jason Jakob LOHMUELLER (Pittsburgh, Pennsylvania); Alexander DEITERS (Pittsburgh, Pennsylvania) |
| ABSTRACT | Disclosed are compositions and methods related to the construction and use of universal synthetic notch (synNotch) receptors and chimeric antigen receptor (CAR) T cells. |
| FILED | Thursday, October 03, 2019 |
| APPL NO | 17/282113 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 2039/5156 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/705 (20130101) C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 14/70578 (20130101) C07K 16/2803 (20130101) Original (OR) Class C07K 2319/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267627 | Dhinojwala et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ali Dhinojwala (Akron, Ohio); Mario Echeverri (Northfield, Ohio); Anvay Arun Patil (Cuyahoga Falls, Ohio) |
| ASSIGNEE(S) | THE UNIVERSITY OF AKRON (AKRON, Ohio) |
| INVENTOR(S) | Ali Dhinojwala (Akron, Ohio); Mario Echeverri (Northfield, Ohio); Anvay Arun Patil (Cuyahoga Falls, Ohio) |
| ABSTRACT | In various embodiments, the present invention is directed to photothermal-responsive melanin-based nanocomposites comprising a plurality of natural or synthetic melanin nanoparticles distributed with a polymer matrix suitable for use in anti-counterfeiting, photothermal responsive-communication, sensors, and heat management, among other applications. In some embodiments, the present invention will be an ink, paint, or other coating comprising the photothermal-responsive melanin-based nanocomposites. In some embodiments, the present invention is directed to a written message or design comprising one or more of the photothermal-responsive melanin-based nanocomposites. In some of these embodiments, the written message or design will be comprised of two ore more of the photothermal-responsive melanin-based nanocomposites having different concentrations of natural or synthetic melanin nanoparticles. |
| FILED | Monday, December 13, 2021 |
| APPL NO | 17/549099 |
| CURRENT CPC | Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus B42D 25/382 (20141001) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/26 (20130101) C09D 7/41 (20180101) C09D 7/65 (20180101) C09D 7/67 (20180101) C09D 7/68 (20180101) C09D 11/17 (20130101) Original (OR) Class C09D 163/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267749 | SUPER et al. |
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| FUNDED BY |
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| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Michael SUPER (Lexington, Massachusetts); Alexander L. WATTERS (North Andover, Massachusetts); Philip T. SNELL (Lexington, Massachusetts); Donald E. INGBER (Boston, Massachusetts) |
| ABSTRACT | Described herein are heme-binding compositions and methods relating to their use, for example methods of treatment of sepsis and rhabdomyolysis. |
| FILED | Friday, March 18, 2022 |
| APPL NO | 17/698576 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/805 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/96 (20130101) C12N 9/2474 (20130101) Original (OR) Class Enzymes C12Y 302/01035 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267754 | Badran et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Ahmed Hussein Badran (Cambridge, Massachusetts); David R. Liu (Cambridge, Massachusetts) |
| ABSTRACT | Strategies, reagents, methods, and systems for modulating the mutation rate in cells are provided herein. The strategies, reagents, methods, and systems are broadly applicable for the modulation of mutation rates in cells where high mutation rates and/or control over a broad range of mutation rates is desired, for example, in the context of diversifying a nucleic acid sequence or a plurality of such sequences within a population of cells, for the generation of diversified nucleic acid libraries, and for directed evolution of nucleic acids and encoded products. |
| FILED | Friday, January 21, 2022 |
| APPL NO | 17/581235 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/48 (20130101) C12N 9/1241 (20130101) C12N 15/70 (20130101) C12N 15/102 (20130101) Original (OR) Class C12N 15/1058 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267884 | Rezaei Farkoosh et al. |
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| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Amir Rezaei Farkoosh (Evanston, Illinois); David C. Dunand (Evanston, Illinois); David N. Seidman (Evanston, Illinois) |
| ABSTRACT | This invention discloses a series of low-cost, castable, weldable, brazeable and heat-treatable aluminum alloys based on modifications of aluminum-manganese-based alloys, which turn all the non-heat treatable Mn-containing aluminum alloys into heat treatable alloys with high-strength, ductility, thermal stability, and resistance to creep, coarsening and recrystallization. These alloys inherit the excellent corrosion resistance of the Al—Mn-based alloys and can be utilized in high temperature, high stress and a variety of other applications. The modifications are made through microalloying with one or any combinations of tin, indium, antimony and bismuth at an impurity level of less than 0.02 at. %, which creates nanoscale α-Al(Mn,TM)Si precipitates with a cubic structure (wherein TM is one or more of transition metals, and Mn is the main element) in an Al(f.c.c.)-matrix with a mean radius of about 25 nm and a relatively high volume fraction of about 2%. |
| FILED | Monday, February 14, 2022 |
| APPL NO | 17/670883 |
| CURRENT CPC | Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 7/005 (20130101) Alloys C22C 1/026 (20130101) C22C 21/00 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267924 | Schaefer et al. |
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| FUNDED BY |
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| APPLICANT(S) | Stephen T. Schaefer (Tempe, Arizona); Marko S. Milosavljevic (Phoenix, Arizona); Rajeev Reddy Kosireddy (Tempe, Arizona); Shane R. Johnson (Chandler, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Stephen T. Schaefer (Tempe, Arizona); Marko S. Milosavljevic (Phoenix, Arizona); Rajeev Reddy Kosireddy (Tempe, Arizona); Shane R. Johnson (Chandler, Arizona) |
| ABSTRACT | The invention relates in part to a growth model for the growth of Group III-Group V (III-V) alloys by molecular beam epitaxy (MBE) based on the kinetics of adsorption, desorption, incorporation, anion exchange, anion-assisted removal, and surface droplet accumulation of the Group V elements. The invention also relates to methods to optimize MBE growth conditions used to produce a target III-V alloy composition. The invention is further related to methods of predicting III-V alloy compositions resulting from a set of MBE growth conditions. |
| FILED | Thursday, December 16, 2021 |
| APPL NO | 17/552524 |
| CURRENT CPC | Alloys C22C 28/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/14 (20130101) C23C 14/221 (20130101) C23C 14/548 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 23/02 (20130101) Original (OR) Class C30B 29/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267925 | Tassev |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vladimir Tassev (Beavercreek, Ohio) |
| ABSTRACT | A method of performing heteroepitaxy comprises exposing a substrate to a carrier gas, a first precursor gas, a Group II/III element, and a second precursor gas, to form a heteroepitaxial growth of one of GaAs, AlAs, InAs, GaP, InP, ZnSe, GaSe, CdSe, InSe, ZnTe, CdTe, GaTe, HgTe, GaSb, InSb, AlSb, CdS, GaN, and AlN on the substrate; wherein the substrate comprises one of GaAs, AlAs, InAs, GaP, InP, ZnSe, GaSe, CdSe, InSe, ZnTe, CdTe, GaTe, HgTe, GaSb, InSb, AlSb, CdS, GaN, and AlN; wherein the carrier gas is H2, wherein the first precursor is HCl, the Group II/III element comprises at least one of Zn, Cd, Hg, Al, Ga, and In; and wherein the second precursor is one of AsH3 (arsine), PH3 (phosphine), H2Se (hydrogen selenide), H2Te (hydrogen telluride), SbH3 (hydrogen antimonide), H2S (hydrogen sulfide), and NH3 (ammonia). The process may be an HVPE (hydride vapor phase epitaxy) process. |
| FILED | Thursday, April 28, 2022 |
| APPL NO | 17/661052 |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/04 (20130101) Original (OR) Class C30B 25/18 (20130101) C30B 29/42 (20130101) C30B 29/44 (20130101) C30B 29/48 (20130101) C30B 29/406 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/3556 (20130101) G02F 1/3558 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0254 (20130101) H01L 21/0262 (20130101) H01L 21/02293 (20130101) H01L 21/02389 (20130101) H01L 21/02392 (20130101) H01L 21/02395 (20130101) H01L 21/02398 (20130101) H01L 21/02458 (20130101) H01L 21/02461 (20130101) H01L 21/02463 (20130101) H01L 21/02466 (20130101) H01L 21/02505 (20130101) H01L 21/02543 (20130101) H01L 21/02546 (20130101) H01L 21/02549 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267927 | Vangala et al. |
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| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shivashankar R. Vangala (Mason, Ohio); Vladimir Tassev (Beavercreek, Ohio) |
| ABSTRACT | A method of performing heteroepitaxy comprises exposing an OP-GaAs template in an HVPE reactor to a carrier gas, a first precursor gas, a second precursor gas (2pg), a Group II element, and a third precursor gas (3pg), to form an epitaxial growth of one of GaAs, GaP, and GaAsP directly on the OP-GaAs template; wherein the carrier gas is H2, wherein the first precursor is HCl, the Group II element is Ga; and wherein the second (V or VI group) precursor is one or more of AsH3 (arsine) and PH3 (phosphine), and the third precursor is one or more of PH3 and AsH3. For an epitaxial growth of GaAsP, the method may further comprise flowing the second and third precursors through the HVPE reactor at a 2pg:3pg ratio of about 1:0; heating the OP-template to 500° C.-900° C.; and gradually changing the 2pg:3pg ratio toward 0:1 over time. |
| FILED | Monday, February 22, 2021 |
| APPL NO | 17/181201 |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/20 (20130101) Original (OR) Class C30B 25/165 (20130101) C30B 29/42 (20130101) C30B 29/44 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0262 (20130101) H01L 21/02395 (20130101) H01L 21/02409 (20130101) H01L 21/02433 (20130101) H01L 21/02543 (20130101) H01L 21/02546 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220268240 | Starkey et al. |
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| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ryan Starkey (Tucson, Arizona); Dario N. Altamirano (Tuscon, Arizona); John Meschberger (Sahuarita, Arizona) |
| ABSTRACT | A rocket booster has an annular shape, with a casing defining an annular space therewithin, and a solid rocket fuel in the annular spacing. The rocket booster also includes one or more nozzle pieces, mechanically coupled to the casing, that define one or more nozzles at the aft side of the rocket booster. The rocket booster may be mechanically coupled to an object protruding from the back of a fuselage of a flight vehicle, such as a missile. For example, the rocket booster may be placed around an aft turbojet nozzle of the flight vehicle. This allows the rocket booster to be used in situations where primary propulsion must be running both before and after (and perhaps during) the firing of the rocket booster. |
| FILED | Monday, February 22, 2021 |
| APPL NO | 17/181162 |
| CURRENT CPC | Jet-propulsion Plants F02K 9/32 (20130101) F02K 9/97 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220268691 | ARMANI et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrea M. ARMANI (Los Angeles, California); Kylie TRETTNER (Los Angeles, California) |
| ABSTRACT | Many samples (inorganic and organic) have magnetic properties. This adaptor which is comprised of an electromagnet and a sample holder (slide) can be directly mounted on a standard microscope (upright or inverted). The magnetic field is uniform across the sample and can be modified (due to the electromagnet design). The mount allows changing the field while simultaneously imaging the sample. Notably, the universality of the adaptor design will allow it to enable a wide range of investigations, impacting numerous fields. |
| FILED | Tuesday, February 22, 2022 |
| APPL NO | 17/677617 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/1717 (20130101) Original (OR) Class G01N 33/5005 (20130101) G01N 2021/1727 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220268733 | Wilkins et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Benjamin P Wilkins (Jasper, Indiana); Jonathan M Dilger (Bloomington, Indiana); Kelly M Thoreson (Bloomington, Indiana); Brooks P Proctor (Bloomington, Indiana) |
| ABSTRACT | The invention relates to a method and apparatus for evaluating reaction molecular byproducts of pyrotechnic reactions. A closed calorimetry bomb holds pyrotechnic material, which is detonated by a charge. The calorimetry bomb is vented directly into a gas chromatography machine, where gas phase molecules are separated based on their polarity. The separated molecules are then injected into a mass spectrometer and characterized by their mass fragmentation. The remaining residual solids within the bomb are extracted and injected into a liquid chromatography instrument where they are separated by their polarity. The separated molecules are then injected into a mass spectrometer and characterized by their mass fragmentation pattern. The method provides a complete picture of the reaction pathways and products to aid in regulatory compliance of incorporating energetic materials into real-world applications, particularly those in the family of PFAS containing compositions. |
| FILED | Friday, February 19, 2021 |
| APPL NO | 17/179501 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/26 (20130101) G01N 27/626 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220268785 | Shi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois); Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tujin Shi (Richland, Washington); Huiping Liu (Chicago, Illinois); Chia-Feng Tsai (West Richland, Washington); David Scholten (Chicago, Illinois); Reta Birhanu Kitata (Richland, Washington); Carolina Reduzzi (Evanston, Illinois) |
| ABSTRACT | Disclosed are compositions and methods for performing a proteomic analysis. Particularly disclosed are compositions and methods for preparing a sample for quantitative single-cell proteomics. |
| FILED | Monday, February 21, 2022 |
| APPL NO | 17/651896 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6848 (20130101) Original (OR) Class G01N 2440/00 (20130101) G01N 2560/00 (20130101) G01N 2570/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220268851 | Epureanu et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bogdan I. Epureanu (Ann Arbor, Michigan); Ganghyeok Im (Ann Arbor, Michigan); Wei Lu (Northville, Michigan); Bogdan Ioan Popa (Ann Arbor, Michigan) |
| ABSTRACT | A battery cell in which a liquid electrolyte is disposed and an acoustic transducer in mechanical communication with the battery cell. The acoustic transducer is configured to generate acoustic waves. The acoustic waves have a wavelength larger than a dimension of the battery cell such that the acoustic waves generate cavitation bubbles in the electrolyte. |
| FILED | Tuesday, February 22, 2022 |
| APPL NO | 17/677627 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/02 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 31/385 (20190101) G01R 31/392 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220268996 | Demkov et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexander A. Demkov (Austin, Texas); John Elliott Ortmann (Austin, Texas); Agham Posadas (Round Rock, Texas) |
| ABSTRACT | Various embodiments provide for systems and techniques for the successful fabrication of metal oxide (TMO)-on-glass layer stacks via direct deposition. The resulting samples feature epitaxial, strontium titanate (STO) or barium titanate (BTO) films on silicon dioxide (SiO2) layers, forming STO- or BTO-buffered SiO2 pseudo-substrates. As the integration of TMO films on silicon rely on an STO or BTO buffer layer, a wide variety of TMO-based integrated devices (e.g., circuits, waveguides, etc.) can be fabricated from the TMO-on-glass platform of the present technology. Moreover, the STO, or the BTO, survives the fabrication process without a corresponding degradation of crystalline quality, as evidenced by various objective measures. |
| FILED | Friday, April 29, 2022 |
| APPL NO | 17/733777 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/34 (20130101) C23C 14/082 (20130101) C23C 14/083 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 23/025 (20130101) C30B 29/32 (20130101) Optical Elements, Systems, or Apparatus G02B 6/131 (20130101) G02B 6/12002 (20130101) Original (OR) Class G02B 2006/12038 (20130101) G02B 2006/12047 (20130101) G02B 2006/12061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220269096 | Teague |
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| FUNDED BY |
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| APPLICANT(S) | Government of the United State, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph D. Teague (Albuquerque, New Mexico) |
| ABSTRACT | A method for triggering switches in a defined order comprises providing two or more PCSS devices and a compatible optical trigger; projecting a beam from the optical trigger; splitting the optical beam into two or more paths toward the two or more PCSS devices, wherein each of the two or more paths has a different length such that each of the two or more PCSS devices are triggered with defined time differentials. Each of the defined path lengths may be determined with the speed of light from the optical trigger along the two or more paths in order to achieve the desired switch-timing differential. The optical path consists of at least one of an optical fiber, a mirror arrangement, and a lens arrangement. Path lengths may be controlled by different fiber lengths, and transmitting a beam through a solid having a higher index of refraction than other beam path(s). |
| FILED | Wednesday, January 05, 2022 |
| APPL NO | 17/647045 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/14 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220269142 | Borlaug |
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| FUNDED BY |
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| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | David B. Borlaug (Los Angeles, California) |
| ABSTRACT | This application relates to circuits and methods for dynamically correcting DC bias and suppressing optical carrier frequency in electro-optic modulators (EOMs). A DC bias voltage for a control path may be determined using a control path DC bias structure. DC bias in a signal path may be corrected by applying the DC bias voltage, or a function thereof, to a signal path DC bias structure. Signal path and control path RF signal structures may be operated for a time period during which their DC biases drift together. An updated DC bias voltage for the control path may be determined using the control path DC bias structure. The drift of DC bias in the signal path may be corrected by applying the updated DC bias voltage, or a function thereof, to the signal path DC bias structure. |
| FILED | Tuesday, February 23, 2021 |
| APPL NO | 17/182938 |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/212 (20210101) G02F 1/2255 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220269168 | LeDuc et al. |
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| FUNDED BY |
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| APPLICANT(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Philip R. LeDuc (Pittsburgh, Pennsylvania); Utku Sonmez (Pittsburgh, Pennsylvania) |
| ABSTRACT | A method of replicating master molds used in the fabrication of microsystems having micron to millimeter sized features. Master molds are replicating using a polymer sheet, which is heated and melted onto an elastomeric mold fabricated from the master mold. The copy molds accurately replicate the geometries of the master mold, such as high aspect ratio features, microposts, and channels with slender sidewalls. The polymer sheet encases the elastomeric mold without the application of an external force, permitting copying without deformation of the features. |
| FILED | Friday, February 25, 2022 |
| APPL NO | 17/681676 |
| CURRENT CPC | Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0017 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220269247 | Behandish et al. |
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| FUNDED BY |
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| APPLICANT(S) | PALO ALTO RESEARCH CENTER INCORPORATED (Palo Alto, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Morad Behandish (Mountain View, California); Saigopal Nelaturi (Mountain View, California) |
| ABSTRACT | Set differences between an as-designed and an as-manufactured model are computed. Topological deviations between the as-designed model and the as-manufactured model are determined based under-deposition and over-deposition features of the set differences. Based on the discrepancies, an input to a manufacturing instrument is changed to reduce topological differences between the as-manufactured model and the as-designed model. |
| FILED | Wednesday, May 04, 2022 |
| APPL NO | 17/736871 |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/4155 (20130101) Original (OR) Class G05B 2219/35193 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20220269301 — PARAMETRICALLY-DRIVEN COHERENT SIGNAL ROUTER FOR QUANTUM COMPUTING AND RELATED METHODS
| US 20220269301 | Hatridge et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Jonathan Hatridge (Pittsburgh, Pennsylvania); David Pekker (Pittsburgh, Pennsylvania); Roger Mong (Pittsburgh, Pennsylvania) |
| ABSTRACT | Systems and methods are provided for routing quantum signals in a quantum computing system. An exemplary method includes providing a waveguide configured to be coupled to at least two modules and a nonlinear element, the waveguide configured to facilitate exchange of quantum information between the at least two modules, the waveguide having at least two waveguide modes, each waveguide mode having a respective frequency; providing a first module couplable to the waveguide at a first module frequency corresponding to a first waveguide mode and a second module couplable to the waveguide at a second mode frequency corresponding to a second waveguide mode; and driving the waveguide via the nonlinear element at a difference frequency equal to a difference between the first module frequency and the second module frequency, thereby causing exchange of quantum information between the first and the second modules. |
| FILED | Friday, March 04, 2022 |
| APPL NO | 17/686702 |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/365 (20130101) G02F 1/3534 (20130101) Electric Digital Data Processing G06F 1/022 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220269322 | Blankenship et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joshua Blankenship (Centerburg, Ohio); James W. Walsh (Columbus, Ohio) |
| ABSTRACT | Adaptive cooling system and methods, docking stations for electronic devices, and systems using the same are described. In embodiments the active cooling systems include a controller that compares a detected temperature of at least a component of a first electronic device to a first temperature threshold (T1D1) for the first electronic device. When the first temperature is ≥T1D1, the controller may issue a control signal that causes a cooling system for a second electronic device to operate at a defined duty level. In embodiments the adaptive cooling systems are incorporated into equipment for a vehicle, such as a vehicle center console. The docking stations may function as a battery eliminator and/or an uninterruptible power supply, and may include a mount, a power connector, and optionally a data connection, which may couple to corresponding device power and device data connections of an electronic device that is coupled to the mount. |
| FILED | Friday, February 25, 2022 |
| APPL NO | 17/680699 |
| CURRENT CPC | Electric Digital Data Processing G06F 1/188 (20130101) G06F 1/203 (20130101) Original (OR) Class G06F 1/1632 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220269472 | Nusimow |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | US Gov't as represented by Secretary of Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Avi Nusimow (Fort Walton Beach, Florida) |
| ABSTRACT | An acoustic gunshot replicator device includes a microphone attachable proximate to a barrel of a firearm to sense a sound caused by a gunshot by the firearm. The device includes an audio output device configured to replicate the sound. The device includes a recording device that is communicatively coupled to the microphone and the audio output device and that is configured to record the sound sensed by the microphone and playback the recorded sound using the audio output device. A record control attachable to the firearm is communicatively coupled to the recording device to prompt recording of the sound in response to a first user input. A playback control attachable to the firearm is communicatively coupled to the recording device to prompt playback of the sound in response to a second user input. |
| FILED | Monday, February 08, 2021 |
| APPL NO | 17/169910 |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 33/04 (20130101) Electric Digital Data Processing G06F 3/165 (20130101) Original (OR) Class Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 1/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220269500 | Graham et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew Graham (Havre de Grace, Maryland); Raymond Steeley (Bel Air, Maryland); Eugene Thompson (Oxford, Pennsylvania); Thomas Rinaldi (Aberdeen Proving Ground, Maryland); Christopher Myers (West Grove, Pennsylvania) |
| ABSTRACT | Various embodiments that pertain to device software is described. A decision can be made by a device on if the device should download an update for device software, such as a software patch. When the device decides that it should download the update, the device can download the appropriate update. In one example, the update can be downloaded by way of a patch portal that communicates with a patch database. The device can request the patch for the software and in response the device can be provided access to the patch by way of the patch portal. |
| FILED | Thursday, May 12, 2022 |
| APPL NO | 17/742429 |
| CURRENT CPC | Electric Digital Data Processing G06F 8/658 (20180201) Original (OR) Class G06F 21/30 (20130101) G06F 21/57 (20130101) Computer Systems Based on Specific Computational Models G06N 5/025 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 47/805 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220269633 | Patrick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Patrick (McKinney, Texas); Tony Brewer (Plano, Texas) |
| ABSTRACT | Implementations of the present disclosure are directed to systems and methods for mapping point-to-point channels to packet virtual channels. A chip with an point-to-point interface converts point-to-point data to a packet format. The point-to-point channels are mapped to virtual channels of the packet transmission protocol. Information from multiple point-to-point channels may be combined in a single packet. Among the benefits of implementations of the present disclosure is that point-to-point devices may be connected to a packetized network without losing the benefits of separate channels for different types of communication. This allows existing point-to-point devices to communicate using a packetized network without internal modification or performance degradation. |
| FILED | Friday, May 13, 2022 |
| APPL NO | 17/744085 |
| CURRENT CPC | Electric Digital Data Processing G06F 13/385 (20130101) Original (OR) Class G06F 13/4031 (20130101) G06F 13/4282 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 45/74 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220269707 | MUGAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PULSELIGHT HOLDINGS, INC. (AUSTIN, Texas) |
| ASSIGNEE(S) | PULSELIGHT HOLDINGS, INC. (AUSTIN, Texas) |
| INVENTOR(S) | JONATHAN WILLIAM MUGAN (BUDA, Texas); LAURA HITT (AUSTIN, Texas); JIMMIE GOODE (AUSTIN, Texas); RUSS GREGORY (AUSTIN, Texas); YUAN QU (AUSTIN, Texas) |
| ABSTRACT | A recurrent neural network (RNN) method implemented on a computer system is used to produce summaries of unstructured text generated by multiple networks of individuals interacting over time by encoding the unstructured text into intermediate representations and decoding the intermediate representations into summaries of each network. Parameter data for the RNN is obtained by using multiple different versions of the same source texts to train the computer system. The method and computer system can be used to identify which of the networks match a query by determining which network generates the query with low or lowest cost. |
| FILED | Monday, February 28, 2022 |
| APPL NO | 17/683321 |
| CURRENT CPC | Electric Digital Data Processing G06F 16/334 (20190101) G06F 16/345 (20190101) Original (OR) Class G06F 40/30 (20200101) G06F 40/58 (20200101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220269778 | JUNGWIRTH |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army DEVCOM Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | PATRICK W. JUNGWIRTH (Bel Air, Maryland) |
| ABSTRACT | A computing architecture using at least one state machine to apply security rules to an execution pipeline of a computing device (e.g., microprocessor) and generate error notifications (e.g., hardware exceptions) when content within the execution pipeline impacts computer security. |
| FILED | Friday, February 18, 2022 |
| APPL NO | 17/675254 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/3004 (20130101) G06F 9/3861 (20130101) G06F 9/4498 (20180201) G06F 9/4812 (20130101) G06F 9/30079 (20130101) G06F 21/54 (20130101) Original (OR) Class G06F 21/554 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220269969 | Carrol et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Streamline Automation LLC (Huntsville, Alabama); Wake Forest University (Winston-Salem, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David L. Carrol (Winston Salem, North Carolina); Alton J. Reich (Huntsville, Alabama); Roberto Di Salvo (Cincinnati, Ohio) |
| ABSTRACT | A qubit device includes a crystal immobilized on a substrate and in contact with electrodes. The crystal exhibits a charge pair symmetry and with an electron current moving clockwise, counter clockwise, or both. The current in can be placed in a state of superposition wherein the current is unknown until it is measured, and the direction of the current is measured to produce a binary output corresponding to a logical zero or a logical one. A state of the qubit device is monitored by measuring a voltage, a current, or a magnetic field and assigning a superposition or base state depending on a threshold value. |
| FILED | Wednesday, October 21, 2020 |
| APPL NO | 17/635716 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/40 (20220101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/24 (20130101) H01L 29/423 (20130101) H01L 29/66977 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220269972 | Bandyopadhyay et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Saumil Bandyopadhyay (Cambridge, Massachusetts); Ryan HAMERLY (Cambridge, Massachusetts); Dirk Robert ENGLUND (Brookline, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Saumil Bandyopadhyay (Cambridge, Massachusetts); Ryan HAMERLY (Cambridge, Massachusetts); Dirk Robert ENGLUND (Brookline, Massachusetts) |
| ABSTRACT | Programmable photonic circuits of reconfigurable interferometers can be used to implement arbitrary operations on optical modes, providing a flexible platform for accelerating tasks in quantum simulation, signal processing, and artificial intelligence. A major obstacle to scaling up these systems is static fabrication error, where small component errors within each device accrue to produce significant errors within the circuit computation. Mitigating errors usually involves numerical optimization dependent on real-time feedback from the circuit, which can greatly limit the scalability of the hardware. Here, we present a resource-efficient, deterministic approach to correcting circuit errors by locally correcting hardware errors within individual optical gates. We apply our approach to simulations of large-scale optical neural networks and infinite impulse response filters implemented in programmable photonics, finding that they remain resilient to component error well beyond modern day process tolerances. Our error correction process can be used to scale up programmable photonics within current fabrication processes. |
| FILED | Monday, December 20, 2021 |
| APPL NO | 17/556033 |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/212 (20210101) Computer Systems Based on Specific Computational Models G06N 10/40 (20220101) G06N 10/70 (20220101) Original (OR) Class Transmission H04B 10/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220269974 | BHASKAR et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mihir Keshav BHASKAR (Cambridge, Massachusetts); Denis D. SUKACHEV (Cambridge, Massachusetts); Christian Thieu NGUYEN (Cambridge, Massachusetts); Bartholomeus MACHIELSE (Cambridge, Massachusetts); David S. LEVONIAN (Cambridge, Massachusetts); Ralf RIEDINGER (Cambridge, Massachusetts); Mikhail D. LUKIN (Cambridge, Massachusetts); Marko LONCAR (Cambridge, Massachusetts) |
| ABSTRACT | Systems and methods are disclosed for making a quantum network node. A plurality of scoring function F values are calculated for an array of at least two photonic crystal cavity unit cells, each having a lattice constant a and a hole having a length Hx and a width Hy. A value of a, a value of Hx, and a value of Hy are selected for which a scoring function value is at a maximum. A waveguide region and the array of at least two photonic crystal cavity unit cells based on the selected values are formed on a substrate. At least one ion between a first photonic crystal cavity unit cell and a second photonic crystal cavity unit cell are implanted and annealed into a quantum defect. A coplanar microwave waveguide is formed on the substrate in proximity to the array of at least two photonic crystal cavity unit cells. |
| FILED | Thursday, July 16, 2020 |
| APPL NO | 17/623757 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Optical Elements, Systems, or Apparatus G02B 6/1225 (20130101) Computer Systems Based on Specific Computational Models G06N 10/70 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220270787 | DeBry et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kyle DeBry (Columbus, Ohio); Gregory Lafyatis (Columbus, Ohio) |
| ABSTRACT | An example method for connectorizing a superconducting cable is described herein. The method can include depositing an oxide layer on a surface of a superconducting cable, electroplating a metal layer on the surface of the superconducting cable, and soldering a connector to the metal layer coated on the surface of the superconducting cable. The oxide layer allows the metal layer to adhere to the surface of the superconducting cable. |
| FILED | Monday, March 21, 2022 |
| APPL NO | 17/699658 |
| CURRENT CPC | Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 12/06 (20130101) H01B 13/222 (20130101) Original (OR) Class Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 24/40 (20130101) H01R 43/02 (20130101) Installation of Electric Cables or Lines, or of Combined Optical and Electric Cables or Lines H02G 15/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220270807 | Yao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yuan Yao (Tarrytown, New York); Todd Edward Takken (Brewster, New York); Andrew Ferencz (Southborough, Massachusetts); Xin Zhang (Chappaqua, New York); Liam Daley McAuliffe (Yorktown Heights, New York) |
| ABSTRACT | Embodiment of the present invention includes a magnetic structure and a magnetic structure used in a direct current (DC) to DC energy converter. The magnetic structure has an E-core and a plate, with the plate positioned in contact or in near contact with the post surfaces of the E-core. The E-core has a base, a no-winding leg, a transformer leg, and an inductor leg. The no-winding leg, the transformer leg, and the inductor leg are perpendicular and magnetically in contact with the base. The plate is a flat slab with lateral dimensions generally larger than its thickness. The plate has a plate nose that overlaps a top no-winding leg surface of the no-winding leg with a no-winding gap area to form a no-winding gap with a no-winding gap reluctance. The plate also has a plate end that overlaps a top inductor leg surface of the inductor leg with an inductor gap area to form an inductor gap with an inductor gap reluctance. In some embodiments, e.g., where the duty cycle is less than 50 percent, the inductor gap reluctance will be designed to be less than the no-winding gap reluctance. In these cases, the majority of the magnetic flux that passes through the transformer leg will return through the inductor leg, instead of through the no-winding leg. The inductor and no-winding gap reluctances can he adjusted, so that the electromotive force applied to a charge passing through the inductor will partially cancel the electromotive force applied by the transformer secondary. The gap reluctance ratio can be defined, so that the difference in secondary and inductor electromotive forces is equal to the output voltage defined by an optimal no-ripple duty cycle. In this way no changing current is required through the inductor to create a dI/dt inductive voltage drop across the output inductor. Zero output current ripple is achieved. Various embodiments of the plate, plate shape, and no-winding leg are disclosed. These embodiments allow achieving a high ratio of no-winding gap reluctance to inductor gap reluctance, for practical, affordable magnetic material structures and aspect ratios. A high gap reluctance ratio enables zero output current ripple for the high transformer turns ratios that are needed to achieve high input to output voltage ratios. The embodiments therefore allow achieving low output current ripple for 48 V or higher input voltages, 1 V or lower output voltages, and high output currents. |
| FILED | Friday, February 12, 2021 |
| APPL NO | 17/174453 |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/14733 (20130101) H01F 27/26 (20130101) Original (OR) Class H01F 27/28 (20130101) H01F 41/0206 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/33576 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220270891 | Currie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Marc Currie (Washington, District of Columbia); Virginia D. Wheeler (Alexandria, Virginia) |
| ABSTRACT | A method for locally annealing and crystallizing a thin film by directing ultrashort optical pulses from an ultrafast laser into the film. The ultrashort pulses can selectively produce an annealed pattern and/or activate dopants on the surface or within the film. |
| FILED | Tuesday, March 29, 2022 |
| APPL NO | 17/706810 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/477 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220271181 | Teague |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph D. Teague (Albuquerque, New Mexico) |
| ABSTRACT | A photoconductive semiconductor switch (PCSS) comprises a plurality of planar semiconductor layers, adjacent semiconductor layers separated by an insulation layer, forming a thin-film stack; a pair electrical contacts fixed to a perimeter of each of the semiconductor layers; an optical source arranged to project light of a predetermined wavelength through the plurality of semiconductor layers. The thin-film stack may comprise at least 10 layers of alternating semiconductor and insulating layers. The semiconductor and insulator layers consist of at least one of GaAs, GaN, GaP, AlN, GaSe, ZnSe, ZnTe, GaSb, InAs, GaN, AlAs, InP, CdS, InSe, CdTe, HgTe, InSb, AlSb, and AlGaN. The contacts consist of at least one of a doped semiconductor material. The optical source illuminates the thin-film stack from at least one of their edges, i.e. parallel to the thin-film layers, or straight through the thin-film stack, i.e. perpendicular to the thin-film layers, or any angle in between. |
| FILED | Wednesday, January 05, 2022 |
| APPL NO | 17/647037 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/08 (20130101) Original (OR) Class Pulse Technique H03K 17/78 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220271187 | Andersen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Trond I. Andersen (Cambridge, Massachusetts); Ryan J. Gelly (Cambridge, Massachusetts); Giovanni Scuri (Cambridge, Massachusetts); Bo L. Dwyer (Cambridge, Massachusetts); Dominik S. Wild (Garching, Germany); Rivka Bekenstein (Cambridge, Massachusetts); Andrey Sushko (Cambridge, Massachusetts); Susanne F. Yelin (Cambridge, Massachusetts); Philip Kim (Cambridge, Massachusetts); Hongkun Park (Cambridge, Massachusetts); Mikhail D. Lukin (Cambridge, Massachusetts) |
| ABSTRACT | An optical device useful for spatial light modulation. The device comprises: a semiconductor layer having a first surface and a second surface, the semiconductor having an electric field-dependent resonance wavelength; a first electrode electrically connected to the semiconductor layer; a first insulating layer adjacent to the first surface of the semiconductor layer, and a second insulating layer adjacent to the second surface of the semiconducting layer, the first and the second insulating layers each being optically transparent at the resonance wavelength; a first group of at least one gate electrodes disposed adjacent to the first insulating layer, and a second group of at least one gate electrodes disposed adjacent to the second insulating layer, each gate electrode being at least 80% optically transparent at the resonance wavelength; wherein the first and the second groups of gate electrodes, taken together, form at least two regions in the semiconductor layer, an electrostatic field in each of the at least two regions being independently controllable by application of voltage to the first and the second groups of gate electrodes, the at least two regions abutting each other along at least one boundary. |
| FILED | Wednesday, February 23, 2022 |
| APPL NO | 17/678393 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/032 (20130101) H01L 31/1136 (20130101) Original (OR) Class H01L 31/022466 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220271218 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jian-Ping Wang (Shoreview, Minnesota); Thomas Jon Peterson (Lauderdale, Minnesota); Anthony William Hurben (Bloomington, Minnesota); Delin Zhang (Saint Paul, Minnesota) |
| ABSTRACT | A magnetic device may include a layer stack including a work function structure, a dielectric layer, and a ferromagnetic layer, where the ferromagnetic layer is positioned between the work function structure and the dielectric layer. The work function structure is configured to deplete electrons from the ferromagnetic layer or accumulate electrons in the ferromagnetic layer. A magnetization orientation of the ferromagnetic layer is configured to be switched by a voltage applied across the layer stack or by a voltage applied across or through the work function structure. |
| FILED | Friday, February 19, 2021 |
| APPL NO | 17/249105 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/049 (20130101) Static Stores G11C 11/161 (20130101) G11C 11/1673 (20130101) G11C 11/1675 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/222 (20130101) H01L 43/02 (20130101) H01L 43/10 (20130101) Original (OR) Class H01L 43/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220271242 | Leem et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Jung Woo Leem (West Lafayette, Indiana); Seung Ho Choi (West Lafayette, Indiana); Young L. Kim (West Lafayette, Indiana) |
| ABSTRACT | A method of inactivating harmful microorganisms of a filtration medium including pathogenic bacteria and viruses is disclosed which includes placing a predetermined quantity of a hybridized fluorescent silk on to a filtration medium, applying light for a predetermined amount of time to the placed quantity of the hybridized fluorescent silk, and passing a fluid through the medium, wherein the fluid is one of substantially air or substantially water, wherein the hybridized fluorescent silk is one of KillerRed, SuperNova, KillerOrange, Dronpa, TurboGFP, mCherry, or any combination thereof. |
| FILED | Friday, March 25, 2022 |
| APPL NO | 17/704235 |
| CURRENT CPC | Preserving, e.g by Canning, Meat, Fish, Eggs, Fruit, Vegetables, Edible Seeds; Chemical Ripening of Fruit or Vegetables; the Preserved, Ripened, or Canned Products A23B 7/015 (20130101) A23B 7/154 (20130101) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/0052 (20130101) A61L 2/0076 (20130101) A61L 2/084 (20130101) A61L 2/088 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 5/0624 (20130101) A61N 2005/0663 (20130101) Separation B01D 29/62 (20130101) B01D 46/66 (20220101) Peptides C07K 14/43504 (20130101) C07K 14/43586 (20130101) C07K 19/00 (20130101) C07K 2319/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/14 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/2018 (20130101) H01G 9/2059 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0093 (20130101) Original (OR) Class H01L 51/442 (20130101) H01L 51/4253 (20130101) H01L 2251/301 (20130101) H01L 2251/306 (20130101) H01L 2251/308 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220271246 | Hou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shaocong Hou (Lu'An, China PRC); Stephen R. FORREST (Ann Arbor, Michigan) |
| ABSTRACT | An organic photovoltaic device comprises a substrate, a reflector positioned over the substrate, a first electrode positioned over at least a first portion of the reflector, a polaritonic antenna layer positioned over a second portion of the reflector different from the first portion, electrically connected to the first electrode, and at least one unit reaction cell positioned over at least part of the first electrode, the at least one unit reaction cell comprising a heterojunction layer comprising a donor material and an acceptor material, positioned over the first electrode, and a second electrode positioned over the heterojunction, wherein the polaritonic antenna and the reflector are configured to convert incoming photonic energy to polaritons. A method of fabricating an organic photovoltaic device is also disclosed. |
| FILED | Tuesday, February 08, 2022 |
| APPL NO | 17/666664 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0016 (20130101) H01L 51/0046 (20130101) H01L 51/441 (20130101) H01L 51/447 (20130101) Original (OR) Class H01L 51/4253 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220271250 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Byungjun Lee (Ann Arbor, Michigan); Jongchan Kim (Ann Arbor, Michigan); Stephen R. Forrest (Ann Arbor, Michigan) |
| ABSTRACT | An organic electronic optoelectronic device comprises a substrate, a first electrode positioned over the substrate, a first organic buffer layer positioned over the first electrode, and a first inorganic emissive layer positioned over the first organic buffer layer. A method of fabricating an organic optoelectronic device is also disclosed. |
| FILED | Wednesday, January 26, 2022 |
| APPL NO | 17/585384 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/56 (20130101) H01L 51/504 (20130101) H01L 51/5004 (20130101) H01L 51/5012 (20130101) Original (OR) Class H01L 51/5056 (20130101) H01L 51/5088 (20130101) H01L 51/5262 (20130101) H01L 2251/301 (20130101) H01L 2251/558 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220271375 | Evans et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Aspen Aerogels, Inc. (Northborough, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Owen Richard Evans (Chelmsford, Massachusetts); Nicholas Anthony Zafiropoulos (Wayland, Massachusetts); Shannon Olga White (Bolton, Massachusetts); Wenting Dong (Marlborough, Massachusetts); Wendell E. Rhine (Belmont, Massachusetts) |
| ABSTRACT | The present invention provides a fiber-reinforced aerogel material which can be used as insulation in thermal battery applications. The fiber-reinforced aerogel material is highly durable, flexible, and has a thermal performance that exceeds the insulation materials currently used in thermal battery applications. The fiber-reinforced aerogel insulation material can be as thin as 1 mm less, and can have a thickness variation as low as 2% or less. Also provided is a method for improving the performance of a thermal battery by incorporating a reinforced aerogel material into the thermal battery. Further provided is a casting method for producing thin fiber-reinforced aerogel materials. |
| FILED | Friday, May 06, 2022 |
| APPL NO | 17/738861 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/0091 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 6/36 (20130101) H01M 6/5072 (20130101) H01M 50/116 (20210101) H01M 50/138 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220271673 | Fogel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Accion Systems, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul E. Fogel (Boston, Massachusetts); Mikhail Filippov (Boston, Massachusetts) |
| ABSTRACT | A polarity-selectable high voltage direct current power supply including a first drive assembly that transforms a first low voltage DC input into a first medium voltage alternating current output; a first HV output assembly that transforms the first LV AC output into a first HV DC output, wherein the first HV output assembly defines a first input stage; a polarity selector coupled between the second output junction of the first drive assembly and the first and second input stages of the first HV output assembly, the polarity selector operable between a first configuration and a second configuration; wherein in the first configuration the first HV DC output has a positive polarity; and wherein in the second configuration the first HV DC output has a negative polarity. |
| FILED | Monday, May 09, 2022 |
| APPL NO | 17/739675 |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 27/022 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/008 (20210501) H02M 1/08 (20130101) H02M 3/335 (20130101) H02M 3/3376 (20130101) H02M 3/33561 (20130101) H02M 3/33569 (20130101) Original (OR) Class H02M 7/103 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220271914 | Diallo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Govermment of the United of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mamadou H. Diallo (San Diego, California); Michael A. August (San Diego, California); Verinder Rana (San Diego, California); Christopher T. Graves (San Diego, California); Scott M. Slayback (San Diego, California); Kevin T. Groarke (San Diego, California) |
| ABSTRACT | A system for providing a secure, collaborative, and distributed computing environment as well as a repository for secure data storage and sharing, the system comprising: FHE manager software residing on a trusted client computer that is configured to generate and store encryption and decryption keys in a memory store; configurations manager software residing on the trusted client computer that is configured to track dynamically-changing cloud resources; an untrusted server in an untrusted cloud environment; a plurality of untrusted, physical, distributed processing nodes where no decryption or encryption functions occur at the processing nodes; a machine learning (ML) manager configured to manage ML algorithms in the processing nodes, wherein the untrusted server is permitted to perform cloud management but not trusted to manipulate the data in plaintext thereby enabling collaborative and secure processing, editing, and merging of the data. |
| FILED | Wednesday, February 24, 2021 |
| APPL NO | 17/183499 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/008 (20130101) Original (OR) Class H04L 9/065 (20130101) H04L 9/0825 (20130101) H04L 9/0894 (20130101) H04L 67/1097 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20220264887 | Somasundaran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ponisseril Somasundaran (New York, New York); Partha Patra (New York, New York) |
| ABSTRACT | Provided are foams and foamable formulations for the decontamination of surfaces, such as disinfection from COVID-19. The formulations can allow deposition of a uniform layer of foam on a given surface without spontaneous drainage of water and with near zero flowability. The foam can adhere to slanted surfaces and surfaces comprised of a variety of materials, including wood, glass, and stone, enabling safe and effective viral decontamination in a number of settings. |
| FILED | Thursday, December 23, 2021 |
| APPL NO | 17/560640 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/16 (20130101) A01N 25/30 (20130101) A01N 33/12 (20130101) A01N 59/00 (20130101) Original (OR) Class Biocidal, Pest Repellant, Pest Attractant or Plant Growth Regulatory Activity of Chemical Compounds or Preparations A01P 1/00 (20210801) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/18 (20130101) A61L 2101/18 (20200801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265172 | Cooks et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert Graham Cooks (West Lafayette, Indiana); Zheng Ouyang (West Lafayette, Indiana); Chien-hsun Chen (West Lafayette, Indiana); Ziqing Lin (West Lafayette, Indiana); Livia Schiavinato Eberlin (Lafayette, Indiana) |
| ABSTRACT | The invention generally relates to enclosed desorption electrospray ionization probes, systems, and methods. In certain embodiments, the invention provides a source of DESI-active spray, in which a distal portion of the source is enclosed within a transfer member such that the DESI-active spray is produced within the transfer member. |
| FILED | Friday, March 11, 2022 |
| APPL NO | 17/692613 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/145 (20130101) A61B 5/1477 (20130101) Original (OR) Class A61B 10/0045 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 11/00 (20130101) A61M 25/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/4833 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0022 (20130101) H01J 49/34 (20130101) H01J 49/167 (20130101) H01J 49/0404 (20130101) H01J 49/0445 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265173 | Zhong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chuan-Jian Zhong (Endwell, New York); Mark D. Poliks (Vestal, New York); Benjamin S. Hsiao (Setauket, New York); Ning Kang (Vestal, New York); Shan Yan (Vestal, New York); Jing Li (Vestal, New York); Shiyao Shan (Vestal, New York); Jin Luo (Vestal, New York) |
| ABSTRACT | Nanoparticle-fibrous membrane composites are provided as tunable interfacial scaffolds for flexible chemical sensors and biosensors by assembling gold nanoparticles (Au NPs) in a fibrous membrane. The gold nanoparticles are functionalized with organic, polymeric and/or biological molecules. The fibrous membranes may include different filter papers, with one example featuring a multilayered fibrous membrane consisting of a cellulose nanofiber (CN) top layer, an electrospun polyacrylonitrile (PAN) nanofibrous midlayer (or alternate material), and a non-woven polyethylene terephthalate (PET) fibrous support layer, with the nanoparticles provided on the fibrous membranes through interparticle molecular/polymeric linkages and nanoparticle-nanofibrous interactions. Molecular linkers may be employed to tune hydrogen bonding and electrostatic and/or hydrophobic/hydrophilic interactions to provide sensor specificity to gases or liquids. The sensors act as chemiresistor-type sensors. A preferred implementation is a sweat sensor. |
| FILED | Saturday, May 14, 2022 |
| APPL NO | 17/744643 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/082 (20130101) A61B 5/145 (20130101) A61B 5/1477 (20130101) Original (OR) Class A61B 5/4266 (20130101) A61B 5/14517 (20130101) A61B 2560/0412 (20130101) A61B 2562/12 (20130101) A61B 2562/0285 (20130101) A61B 2562/0295 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265452 | Park et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Texas A and M University System (College Station, Texas); University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sung Il Park (College Station, Texas); Woo Seok Kim (College Station, Texas); Carlos Arturo Campos (Seattle, Washington) |
| ABSTRACT | In an embodiment, the present disclosure pertains to an organ-specific wireless optogenetic device. In some embodiments, the device includes an electronic circuit, such that the electronic circuit is configured to harvest and convert radio frequency (RF) energy into optical energy and a tether having a μLED, where the μLED illuminates targeted regions in the organ. In an additional embodiment, the present disclosure pertains to a method of treating obesity. In general, the method includes implanting an organ-specific wireless optogenetic device into a subject, activating an RF-power system to produce RF energy, harvesting, by the organ-specific wireless optogenetic device, the RF energy, converting, by the organ-specific wireless optogenetic device, the RF energy into optical energy, illuminating, by the μLED, targeted regions in the stomach of the subject, and stimulating nerve endings to thereby suppress appetite in the subject. |
| FILED | Friday, February 25, 2022 |
| APPL NO | 17/681595 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 5/0013 (20130101) Original (OR) Class Antennas, i.e Radio Aerials H01Q 1/22 (20130101) H01Q 1/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265554 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Liang-Hsun Chen (Cambridge, Massachusetts); Patrick S. Doyle (Cambridge, Massachusetts) |
| ABSTRACT | Compositions contain nanoparticles containing nanocrystals of hydrophobic therapeutic, diagnostic, prophylactic agents, or a combination thereof, encapsulated in thermogelling polymers, such as methyl cellulose. Because of the templating of the compositions on a thermogelling nanoemulsion system, the compositions can be formed with precise control of the sizes of the nanoparticles as well as the high loadings of these hydrophobic therapeutic, diagnostic, prophylactic agents, or a combination thereof. Also described are methods of making and using the compositions. |
| FILED | Tuesday, December 21, 2021 |
| APPL NO | 17/557696 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/006 (20130101) A61K 9/16 (20130101) A61K 9/1075 (20130101) Original (OR) Class A61K 9/2095 (20130101) A61K 47/02 (20130101) A61K 47/26 (20130101) A61K 47/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265833 | SHUKLA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anita SHUKLA (Providence, Rhode Island); Noel VERA-GONZALEZ (San Juan, Puerto Rico) |
| ABSTRACT | The present invention relates generally to antifungal hydrogels to locally deliver antifungal drugs. Specifically, the present invention provides aspartic protease-triggered antifungal hydrogels to locally deliver antifungal drugs that specifically respond to aspartic proteases secreted by virulent, pathogenic Candida. |
| FILED | Monday, February 28, 2022 |
| APPL NO | 17/682782 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/5026 (20130101) A61K 31/7048 (20130101) A61K 38/12 (20130101) A61K 47/32 (20130101) A61K 47/42 (20130101) Original (OR) Class A61K 47/60 (20170801) A61K 47/65 (20170801) A61K 47/6903 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265929 | Gholami |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Autonomous Healthcare, Inc. (Hoboken, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Behnood Gholami (Hoboken, New Jersey) |
| ABSTRACT | The present disclosure describes a closed-loop fluid resuscitation and/or cardiovascular drug administration system that uses continuous measurements and adaptive control architecture. The adaptive control architecture uses a function approximator to identify unknown dynamics and physiological parameters of a patient to compute appropriate infusion rates and to regulate the endpoint of resuscitation. |
| FILED | Thursday, April 28, 2022 |
| APPL NO | 17/731347 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/1723 (20130101) Original (OR) Class A61M 2205/50 (20130101) A61M 2205/52 (20130101) A61M 2205/502 (20130101) A61M 2205/3569 (20130101) A61M 2230/00 (20130101) A61M 2230/06 (20130101) A61M 2230/30 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 20/17 (20180101) G16H 40/63 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220266239 | Bae et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chulsung Bae (Cohoes, New York); Eun Joo Park (Troy, New York); Sangtaik Noh (Troy, New York); Michael Pagels (Troy, New York) |
| ABSTRACT | The electrochemical energy conversion system of the present disclosure includes an anode, a cathode, and an ion exchange membrane including a polymer having an aromatic polymer chain and an alkylated substrate including an alkyl chain, and at least one ionic group. The alkylated substrate is bound to at least one aromatic group in the polymer chain via Friedel-Crafts alkylation of the at least one aromatic group. The alkylation reaction utilizes a haloalkylated tertiary alcohol or a haloalkylated alkene as a precursor. In the presence of an acid catalyst, a carbocation is generated in the precursor which reacts with the aromatic rings of the polymer chain. The at least one ionic group is then replaced with a desired cationic or anionic group using a substitution reaction. The membranes exhibit advantageous stability achieved through a simplified and scalable reaction scheme. |
| FILED | Friday, April 08, 2022 |
| APPL NO | 17/658627 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 39/20 (20130101) B01J 41/14 (20130101) Original (OR) Class Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/2287 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/1032 (20130101) H01M 8/1072 (20130101) H01M 2008/1095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220266246 | Mullner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOISE STATE UNIVERSITY (Boise, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Peter Mullner (Boise, Idaho); Geoffrey Brent Johnston (Boise, Idaho); Aaron Smith (Meridian, Idaho); Andrew Armstrong (Boise, Idaho) |
| ABSTRACT | A magnetic shape memory (MSM) microfluidic device may include a flexible membrane positioned between a channel and an MSM element. The MSM element may engage the flexible membrane to deform the channel at portions of the flexible membrane that are adjacent to non-contracted portions of the MSM element. The flexible membrane may prevent contact between a fluid within the channel and the MSM element. Magnetic field components may be applied to the MSM element and moved along the MSM element enable fluidic flow within the channel while. The device may include an upper portion including the flexible membrane and a lower portion including the MSM element. The upper portion may be interchangeable with additional upper portions. |
| FILED | Tuesday, February 22, 2022 |
| APPL NO | 17/677697 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) Original (OR) Class B01L 3/502707 (20130101) B01L 2200/12 (20130101) B01L 2300/123 (20130101) B01L 2300/0681 (20130101) B01L 2400/043 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220266390 | NEOGI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF NORTH TEXAS (Dallas, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Arup NEOGI (Dallas, Texas); Yuqi JIN (Dallas, Texas); Teng YANG (Dallas, Texas) |
| ABSTRACT | A monitoring technique for a melting process including monitoring a melt pool produced by a heat source during the melting process, the monitoring comprising measuring ultrasonic time of flight of the melt pool via one or more ultrasonic transducers, wherein the melt pool comprises one or more metals, alloys, or a combination thereof. A system for carrying out the monitoring technique, and melting processes and systems utilizing the monitoring technique are also provided. |
| FILED | Tuesday, February 22, 2022 |
| APPL NO | 17/677592 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/28 (20210101) B22F 10/37 (20210101) B22F 12/90 (20210101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/03 (20130101) B23K 26/342 (20151001) Original (OR) Class B23K 26/0624 (20151001) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 50/02 (20141201) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 17/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/07 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220266582 | Anthamatten et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mitchell Anthamatten (Rochester, New York); Alexander A. Shestopalov (Rochester, New York) |
| ABSTRACT | Describes are methods of contacting printing with a shape-memory stamp. For example, disclosed herein are methods of patterning thin films using shape memory contact printing. |
| FILED | Wednesday, February 23, 2022 |
| APPL NO | 17/678222 |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 37/025 (20130101) Original (OR) Class B32B 37/0046 (20130101) B32B 2457/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267211 | Fini et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Elham Fini (Phoenix, Arizona); Robert Allen (Golden, Colorado); Albert Hung (Tempe, Arizona); Matthew Green (Phoenix, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Elham Fini (Phoenix, Arizona); Robert Allen (Golden, Colorado); Albert Hung (Tempe, Arizona); Matthew Green (Phoenix, Arizona) |
| ABSTRACT | An asphalt modifier includes bitumen, polyolefin particles, and one or more alkyl terephthalamides. Preparing an asphalt modifier includes combining one or more alkyl terephthalamides, polyolefin particles, and bitumen, and dispersing the polyolefin particles in the bitumen to yield the asphalt modifier. Digesting polyethylene terephthalate includes combining polyethylene terephthalate with an alkylamine or carboxyalkylamine to yield a reaction mixture, and heating the reaction mixture to a temperature between about 20° C. and about 300° C. to yield an alkyl terephthalamide. |
| FILED | Friday, February 11, 2022 |
| APPL NO | 17/669779 |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 18/20 (20130101) C04B 24/124 (20130101) C04B 26/26 (20130101) Original (OR) Class Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 11/28 (20130101) C08J 2367/02 (20130101) C08J 2377/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267358 | Braddock-Wilking et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Curators Of The University Of Missouri (Columbia, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Janet Braddock-Wilking (St. Louis, Missouri); Teresa Lynn Bandrowsky (St. Peters, Missouri); James Bryan Carroll, II (St. Louis, Missouri) |
| ABSTRACT | The present disclosure provides a new series of compounds exhibiting high fluorescence quantum yields in the solid state. In one embodiment, the compounds include a series of 2,3,4,5-tetraphenylgermoles with the same or different 1,1-substituents. In another embodiment, substituted germafluorenes, germa-fluoresceins/rhodamines, and germapins are described. These germanium heterocycles possess ideal photophysical and thermostability properties, which makes them excellent candidates for chemical or biological sensors, host materials for electroluminescent devices and solar cells, and emissive and/or electron-transport layer components in organic light emitting diode devices. |
| FILED | Tuesday, May 03, 2022 |
| APPL NO | 17/661769 |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/30 (20130101) Original (OR) Class Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/1007 (20130101) C09K 2211/1014 (20130101) C09K 2211/1029 (20130101) C09K 2211/1051 (20130101) C09K 2211/1092 (20130101) C09K 2211/1096 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/90 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/202499 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267562 | Fortman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois); Cornell University (Ithaca, New York); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David J. Fortman (Pittsburgh, Pennsylvania); William R. Dichtel (Wilmette, Illinois); Daylan T. Sheppard (Evanston, Illinois); Kailong Jin (Minneapolis, Minnesota); Christopher J. Ellison (Eden Prairie, Minnesota) |
| ABSTRACT | Disclosed herein are methods for reprocessing polyurethane compositions such as polyurethane foams. The method comprises introducing a polyurethane composition into a compounding device, heating the polyurethane composition to an effective bond-exchange temperature, and compounding the polyurethane composition for an effective bond-exchange time. |
| FILED | Thursday, April 23, 2020 |
| APPL NO | 17/605831 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/04 (20130101) B01J 31/2234 (20130101) B01J 2531/54 (20130101) B01J 2531/842 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/12 (20130101) C08G 18/14 (20130101) C08G 18/42 (20130101) C08G 18/242 (20130101) C08G 18/4812 (20130101) C08G 18/4833 (20130101) C08G 18/7671 (20130101) C08G 2110/0025 (20210101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 11/26 (20130101) Original (OR) Class C08J 2375/06 (20130101) C08J 2375/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267821 | Jewett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois); Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Christopher Jewett (Evanston, Illinois); Jessica Carol Stark (Evanston, Illinois); Matthew P. DeLisa (Ithaca, New York); Thapakorn Jaroentomeechai (Ithaca, New York) |
| ABSTRACT | Disclosed are methods, systems, components, and compositions for cell-free synthesis of glycosylated proteins, which may be utilized in vaccines, including anti- bacterial vaccines. The glycosylated proteins may include a bacterial polysaccharide conjugated to a carrier, which may be utilized to generate an immune response in an immunized host against the polysaccharide conjugated to the carrier. Suitable carriers may include but are not limited to Haemophilus influenzae protein D (PD), Neisseria meningitidis porin protein (PorA), Corynebacterium diphtheriae toxin (CRM 197), Clostridium tetani toxin (TT), and Escherichia coli maltose binding protein, and variants thereof. |
| FILED | Friday, January 10, 2020 |
| APPL NO | 17/310022 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/005 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267838 | Bevilacqua et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Philip C. Bevilacqua (State College, Pennsylvania); Sarah M. Assmann (State College, Pennsylvania); Zhao Su (State College, Pennsylvania); Laura Ritchey (Martinsburg, Pennsylvania); David Mitchell (State College, Pennsylvania) |
| ABSTRACT | The invention provides improved methods for determining the structure of RNA molecules with increased sensitivity, improved data quality, reduced ligation bias, and improved read coverage, incorporating the removal of undesired bi-products and ligation using a fast, efficient, and low-sequence bias hybridization-ligation method. |
| FILED | Tuesday, November 13, 2018 |
| APPL NO | 16/762820 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220268692 | Demers |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Joseph R. Demers (Van Nuys, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph R. Demers (Van Nuys, California) |
| ABSTRACT | A sample cell includes an annular support surrounding a sample region. A set of reflectors of the annular support define an optical path that reflects a source beam in a sequence of alternating directions through the sample region at a plurality of different angles such that the source beam exits the set of reflectors after having passed through the sample region a plurality of times. A micro-cell is positionable in the sample region including multi-dimensionally distributed nano-pores. A slidingly adjustable lens forms part of source and detector photomixing packages. |
| FILED | Tuesday, February 23, 2021 |
| APPL NO | 17/183191 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/31 (20130101) Original (OR) Class G01N 2201/0636 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0203 (20130101) H01L 31/02325 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220268698 | Demers |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Joseph R. Demers (Van Nuys, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph R. Demers (Van Nuys, California) |
| ABSTRACT | A sample cell includes an annular support surrounding a sample region. A set of reflectors of the annular support define an optical path that reflects a source beam in a sequence of alternating directions through the sample region at a plurality of different angles such that the source beam exits the set of reflectors after having passed through the sample region a plurality of times. A micro-cell is positionable in the sample region including multi-dimensionally distributed nano-pores. A slidingly adjustable lens forms part of source and detector photomixing packages. |
| FILED | Tuesday, February 23, 2021 |
| APPL NO | 17/183172 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/3581 (20130101) Original (OR) Class G01N 2201/0636 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220268699 | Pate |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Universtiy of Virginia Patent Foundation (Charlottesville, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brooks Hart Pate (Charlottesville, Virginia) |
| ABSTRACT | A chiral molecule can be defined as a molecule that has a non-superimposable mirror image. These mirror images can be referred to as enantiomers. The enantiomers generally have the same set of bond lengths and bond angles in their three-dimensional geometry. Apparatus and techniques described herein can be used to perform analysis of chiral molecules using cavity-enhanced molecular rotational spectroscopy. A sample cell can define a resonant cavity, and a sample introduction port can provide pulse-jet injection of an analyte molecule and a chiral tag to allow analysis of a complex comprising the analyte and chiral tag. |
| FILED | Friday, January 07, 2022 |
| APPL NO | 17/647364 |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/16 (20130101) G01J 3/30 (20130101) G01J 3/447 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/3586 (20130101) Original (OR) Class G01N 22/00 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 23/20 (20130101) H01J 23/207 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220268707 | Humphrey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Simon M. Humphrey (Austin, Texas); Bradley J. Holliday (Austin, Texas); Matthew D. Moore (Austin, Texas); Samuel G. Dunning (Washington, District of Columbia) |
| ABSTRACT | Embodiments of the present disclosure pertain to methods of monitoring an environment for the presence of a solvent by: (i) exposing the environment to a luminescent compound, where the relative luminescence emission intensity of the luminescent compound changes upon interaction with the solvent; and (ii) monitoring a change in the relative luminescence emission intensity of the luminescent compound, where the absence of the change indicates the absence of the solvent from the environment, and where the presence of the change indicates the presence of the solvent in the environment. The luminescent compounds include a phosphorous atom with one or more carboxyl groups, where the carboxyl groups are coordinated with one or more metallic ions (e.g., lanthanide ions and yttrium ions). The present disclosure also pertains to sensors for monitoring an environment for the presence of a solvent, where the sensors include one or more of the aforementioned luminescent compounds. |
| FILED | Monday, May 09, 2022 |
| APPL NO | 17/740135 |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/182 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/78 (20130101) Original (OR) Class G01N 31/22 (20130101) G01N 2021/7786 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220268731 | AULT et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey); UT-BATTELLE, LLC (Oak Ridge, Tennessee); University of Hawaii (Honolulu, Hawaii) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jesse AULT (Knoxville, Tennessee); Sangwoo SHIN (Honolulu, Hawaii); Howard A. STONE (Princeton, New Jersey); Jie FENG (Princeton, New Jersey); Patrick WARREN (Wirral, United Kingdom) |
| ABSTRACT | Methods described herein, in some embodiments, permit extraction of particle structural and/or surface charge data from gradient induced particle motion in channels. In one aspect, a method of manipulating particle motion comprises introducing a fluid into a channel, the fluid comprising particles, and driving particle accumulation to a preselected location in the channel by setting advective velocity of the fluid to offset diffusiophoretic mobility of the particles at the preselected location. |
| FILED | Thursday, April 14, 2022 |
| APPL NO | 17/720687 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/00 (20130101) G01N 15/1456 (20130101) G01N 27/44721 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220268746 | Anderson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jared L. Anderson (Ames, Iowa); Kosuke Kuroda (Kanazawa, Japan); He Nan (Ames, Iowa) |
| ABSTRACT | A gas chromatographic (GC) column using a zwitterionic compound and methods of use thereof are disclosed herein. The volatile free acids were observed to strongly retain on these zwitterionic compounds-based columns with excellent peak symmetry. By carefully tuning the structures of these zwitterionic compounds, different selectivity toward volatile free acids was demonstrated. These stationary phases possess a wide working range with thermal stabilities at higher temperatures. |
| FILED | Monday, May 09, 2022 |
| APPL NO | 17/662512 |
| CURRENT CPC | Separation B01D 15/36 (20130101) Heterocyclic Compounds C07D 233/60 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/56 (20130101) Original (OR) Class G01N 30/68 (20130101) G01N 30/72 (20130101) G01N 30/74 (20130101) G01N 2030/025 (20130101) G01N 2030/562 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220268963 | LIN et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Ning LIN (Princeton, New Jersey); Renzhi JING (Princeton, New Jersey) |
| ABSTRACT | According to various embodiments, a machine-learning based system for simulating tropical cyclones (TCs) and assessing TC risk is disclosed. The system includes a hierarchical Poisson genesis module configured to develop a Poisson regression and TC genesis simulation on a plurality of clustering grids. The system further includes an analog-wind track module configured to determine movement of a TC by both analog predictors formed by historical track patterns and current in situ wind. The system additionally includes a Markov intensity module configured to determine intensity change of the TC by considering three hidden discrete states of storm intensity change and associating each state with a probability distribution of intensity change. |
| FILED | Wednesday, July 29, 2020 |
| APPL NO | 17/629581 |
| CURRENT CPC | Meteorology G01W 1/10 (20130101) Original (OR) Class Electric Digital Data Processing G06F 30/10 (20200101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6277 (20130101) G06K 9/6297 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220269759 | LEE et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | RUBY LEE (PRINCETON, New Jersey); GUANGYUAN HU (PRINCETON, New Jersey) |
| ABSTRACT | Devices and methods for smartphone impostor detection using behavioral and environmental data are provided. Impostors are attackers who take control of an electronic device (e.g., a smartphone) and gain access to confidential and private information of a legitimate user. Embodiments described herein propose a defense-in-depth mechanism to detect impostors quickly with simple deep learning algorithms, which can achieve better detection accuracy than previous works. Embodiments then consider protecting the privacy of the behavioral and/or environmental data (e.g., collected by one or more sensors) of a user by not exposing it outside the protected device. A recurrent neural network (RNN)-based deep learning algorithm is proposed which uses only sensor data of the legitimate user to learn their normal behavior. Prediction error distribution (PED) is used to enhance the detection accuracy. In some embodiments, a minimalist hardware module, dubbed smartphone impostor detector (SID), is integrated into smartphones for self-contained impostor detection. |
| FILED | Wednesday, February 09, 2022 |
| APPL NO | 17/668142 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/316 (20130101) Original (OR) Class Wireless Communication Networks H04W 12/30 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220269974 | BHASKAR et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mihir Keshav BHASKAR (Cambridge, Massachusetts); Denis D. SUKACHEV (Cambridge, Massachusetts); Christian Thieu NGUYEN (Cambridge, Massachusetts); Bartholomeus MACHIELSE (Cambridge, Massachusetts); David S. LEVONIAN (Cambridge, Massachusetts); Ralf RIEDINGER (Cambridge, Massachusetts); Mikhail D. LUKIN (Cambridge, Massachusetts); Marko LONCAR (Cambridge, Massachusetts) |
| ABSTRACT | Systems and methods are disclosed for making a quantum network node. A plurality of scoring function F values are calculated for an array of at least two photonic crystal cavity unit cells, each having a lattice constant a and a hole having a length Hx and a width Hy. A value of a, a value of Hx, and a value of Hy are selected for which a scoring function value is at a maximum. A waveguide region and the array of at least two photonic crystal cavity unit cells based on the selected values are formed on a substrate. At least one ion between a first photonic crystal cavity unit cell and a second photonic crystal cavity unit cell are implanted and annealed into a quantum defect. A coplanar microwave waveguide is formed on the substrate in proximity to the array of at least two photonic crystal cavity unit cells. |
| FILED | Thursday, July 16, 2020 |
| APPL NO | 17/623757 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Optical Elements, Systems, or Apparatus G02B 6/1225 (20130101) Computer Systems Based on Specific Computational Models G06N 10/70 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220270203 | Tu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of South Florida (Tempa, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yicheng Tu (Tampa, Florida); Ran Rui (Temple Terrace, Florida) |
| ABSTRACT | Disclosed are various embodiments for performing a join operation using a graphics processing unit (GPU). The GPU can receive input data including sequences or tuples. The GPU can initialize a histogram in a memory location shared by threads. The GPU can build the histogram of hash values for the sequences. The GPU can reorder the sequences based on the histogram. The GPU can probe partitions and store the results in a buffer pool. The GPU can output the results of the join. |
| FILED | Friday, April 29, 2022 |
| APPL NO | 17/733217 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/4881 (20130101) Image Data Processing or Generation, in General G06T 1/20 (20130101) G06T 1/60 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220270357 | Goyal et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Diksha Goyal (Tempe, Arizona); Jianming Liang (Scottsdale, Arizona) |
| ABSTRACT | Described herein are means for implementing medical image segmentation using interactive refinement, in which the trained deep models are then utilized for the processing of medical imaging. For instance, an exemplary system is specially configured for operating a two-step deep learning training framework including means for receiving original input images at the deep learning training framework; means for generating an initial prediction image specifying image segmentation by processing the original input images through the base segmentation model to render the initial prediction image in the absence of user input guidance signals; means for receiving user input guidance signals indicating user-guided segmentation refinements to the initial prediction image; means for routing each of (i) the original input images, (ii) the initial prediction image, and (iii) the user input guidance signals to an InterCNN; means for generating a refined prediction image specifying refined image segmentation by processing each of the (i) the original input images, (ii) the initial prediction image, and (iii) the user input guidance signals through the InterCNN to render the refined prediction image incorporating the user input guidance signals; and means for outputting a refined segmentation mask based on application of the user input guidance signals to the deep learning training framework as a guidance signal. Other related embodiments are disclosed. |
| FILED | Friday, February 18, 2022 |
| APPL NO | 17/675929 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) G06T 7/194 (20170101) G06T 2200/24 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/20092 (20130101) G06T 2207/30004 (20130101) Image or Video Recognition or Understanding G06V 10/82 (20220101) G06V 10/7747 (20220101) G06V 10/7788 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220271187 | Andersen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Trond I. Andersen (Cambridge, Massachusetts); Ryan J. Gelly (Cambridge, Massachusetts); Giovanni Scuri (Cambridge, Massachusetts); Bo L. Dwyer (Cambridge, Massachusetts); Dominik S. Wild (Garching, Germany); Rivka Bekenstein (Cambridge, Massachusetts); Andrey Sushko (Cambridge, Massachusetts); Susanne F. Yelin (Cambridge, Massachusetts); Philip Kim (Cambridge, Massachusetts); Hongkun Park (Cambridge, Massachusetts); Mikhail D. Lukin (Cambridge, Massachusetts) |
| ABSTRACT | An optical device useful for spatial light modulation. The device comprises: a semiconductor layer having a first surface and a second surface, the semiconductor having an electric field-dependent resonance wavelength; a first electrode electrically connected to the semiconductor layer; a first insulating layer adjacent to the first surface of the semiconductor layer, and a second insulating layer adjacent to the second surface of the semiconducting layer, the first and the second insulating layers each being optically transparent at the resonance wavelength; a first group of at least one gate electrodes disposed adjacent to the first insulating layer, and a second group of at least one gate electrodes disposed adjacent to the second insulating layer, each gate electrode being at least 80% optically transparent at the resonance wavelength; wherein the first and the second groups of gate electrodes, taken together, form at least two regions in the semiconductor layer, an electrostatic field in each of the at least two regions being independently controllable by application of voltage to the first and the second groups of gate electrodes, the at least two regions abutting each other along at least one boundary. |
| FILED | Wednesday, February 23, 2022 |
| APPL NO | 17/678393 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/032 (20130101) H01L 31/1136 (20130101) Original (OR) Class H01L 31/022466 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220271218 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jian-Ping Wang (Shoreview, Minnesota); Thomas Jon Peterson (Lauderdale, Minnesota); Anthony William Hurben (Bloomington, Minnesota); Delin Zhang (Saint Paul, Minnesota) |
| ABSTRACT | A magnetic device may include a layer stack including a work function structure, a dielectric layer, and a ferromagnetic layer, where the ferromagnetic layer is positioned between the work function structure and the dielectric layer. The work function structure is configured to deplete electrons from the ferromagnetic layer or accumulate electrons in the ferromagnetic layer. A magnetization orientation of the ferromagnetic layer is configured to be switched by a voltage applied across the layer stack or by a voltage applied across or through the work function structure. |
| FILED | Friday, February 19, 2021 |
| APPL NO | 17/249105 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/049 (20130101) Static Stores G11C 11/161 (20130101) G11C 11/1673 (20130101) G11C 11/1675 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/222 (20130101) H01L 43/02 (20130101) H01L 43/10 (20130101) Original (OR) Class H01L 43/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220271230 | KOSCO et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (Thuwal, Saudi Arabia); MPERIAL COLLEGE (London, United Kingdom) |
| ASSIGNEE(S) | |
| INVENTOR(S) | JAN KOSCO (Thuwal, Saudi Arabia); MATTHEW BIDWELL (London, United Kingdom); HYOJUNG CHA (London, United Kingdom); CALVYN T. HOWELLS (Thuwal, Saudi Arabia); JAMES R. DURRANT (London, United Kingdom); IAIN MCCULLOCH (Thuwal, Saudi Arabia) |
| ABSTRACT | A nanoparticle comprises an internal D/A heterojunction, wherein the nanoparticle comprises a HER rate of 64,426±7022 μmolh−1g−1 under broadband visible light illumination. Measured EQEs of the nanoparticle throughout a visible spectrum exceed 5% at 660 to 700 nm. Methods may include fabricating a nanoparticle comprising: preparing individual stock solutions of PTB7-TH and EH-IDTBR in chloroform; heating the individual stock solutions to a complete dissolution; filtering the individual stock solutions; preparing a nanoparticle precursor solution from the filtered individual stock solutions by mixing the individual stock solutions in a ratio of 0-100% EH-IDTBR adding a portion of the nanoparticle precursor solution to a solution of surfactant (SDS or TEBS) in water and mixing to form a pre-emulsion; sonicating the pre-emulsion to form a mini-emulsion; heating the mini-emulsion to remove the chloroform to thereby form a surfactant stabilized nanoparticle dispersion; and filtering the nanoparticle. |
| FILED | Friday, September 11, 2020 |
| APPL NO | 17/639966 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/42 (20130101) B01J 35/0013 (20130101) B01J 37/344 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/02 (20130101) C25B 1/55 (20210101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0036 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220271235 | McGrath et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona, a body corporate (Tucson, Arizona); Southern University of Science and Technology (Shenzhen, Guangdong Province, China PRC) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of the University of Arizona, a body corporate (Tucson, Arizona); Southern University of Science and Technology (Shenzhen, Guangdong Province, China PRC) |
| INVENTOR(S) | Dominic V. McGrath (Tucson, Arizona); Zongxiang Xu (Shenzhen, Guangdon, China PRC); Neal R. Armstrong (Tucson, Arizona) |
| ABSTRACT | The present invention provides methods for increasing stability and efficiency of organic perovskite materials for use in various electronic devices. In particular, methods of the invention use a non-peripheral substituted phthalocyanine for passivating defects in organic perovskite materials, thereby increasing its stability and efficiency relative to the same material in the absence of said non-peripheral substituted phthalocyanine. |
| FILED | Thursday, July 23, 2020 |
| APPL NO | 17/629396 |
| CURRENT CPC | Heterocyclic Compounds C07D 487/22 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0072 (20130101) Original (OR) Class H01L 51/0078 (20130101) H01L 51/0092 (20130101) H01L 51/4246 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220271334 | Reddy Arava et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wayne State University (Detroit, Michigan); University of North Texas (Denton, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Leela Mohana Reddy Arava (Troy, Michigan); Sathish Rajendren (Detroit, Michigan); Jeffry Kelber (Plano, Texas); Aparna Pilli (Josephine, Texas) |
| ABSTRACT | A method of stabilizing a garnet-type solid-state electrolyte (SSE) includes obtaining pellets of SSE, removing surface impurities of the SSE, and depositing a passivation layer onto the SSE after the surface impurities are removed, the passivation layer including two of boron, carbon, and nitrogen. |
| FILED | Wednesday, February 23, 2022 |
| APPL NO | 17/678450 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/45555 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/052 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2300/0071 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220271784 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kefei Wu (San Diego, California); Mona Mostafa Hella (Watervliet, New York) |
| ASSIGNEE(S) | RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York) |
| INVENTOR(S) | Kefei Wu (San Diego, California); Mona Mostafa Hella (Watervliet, New York) |
| ABSTRACT | One embodiment provides a broadband signal source. The broadband signal source includes a number, n, signal paths and a combiner circuitry. Each signal path, i, includes a programmable phase shifter circuitry, an amplifier circuitry and a harmonic generation circuitry. The programmable phase shifter circuitry is configured to phase shift a path input signal by a respective phase angle, θi. The path input signal corresponds to a source input signal having a fundamental frequency, f, and an input signal bandwidth. The amplifier circuitry is configured to amplify the phase shifted path input signal. The harmonic generation circuitry is configured to generate a path output signal including a plurality of harmonics of the amplified phase shifted path input signal. The combiner circuitry is configured to combine the number, n, path output signals to produce a broadband output signal having an output signal center frequency greater than the input signal fundamental frequency and an output signal bandwidth greater than the input signal bandwidth. |
| FILED | Tuesday, July 28, 2020 |
| APPL NO | 17/631026 |
| CURRENT CPC | Transmission H04B 1/0483 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 27/04 (20130101) H04L 27/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220272122 | Kaabouch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of North Dakota (Grand Forks, North Dakota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Naima Kaabouch (Grand Forks, North Dakota); Mohsen Riahi Manesh (Grand Forks, North Dakota) |
| ABSTRACT | The present subject matter provides improved solutions for autonomous vehicle malicious control attacks. One technical solution for detecting and mitigating autonomous vehicle malicious control attacks includes receiving a malicious control signal, determining signal characteristics based on the malicious control signal, determining an autonomous vehicle attack based on signal characteristics, determining an attack countermeasure based on the attack determination, and sending a modified autonomous vehicle control signal to an autonomous vehicle based on the attack countermeasure. This solution may further include sending the signal characteristics to an autonomous vehicle attack machine learning (ML) system and receiving ML signal characteristics from the autonomous vehicle attack ML system, where the attack determination is based on the ML signal characteristics. This solution may further include sending the attack determination to the autonomous vehicle attack ML system and receiving the ML attack determination from the autonomous vehicle attack ML system, where the generation of the attack countermeasure is further based on the ML attack determination. |
| FILED | Wednesday, February 24, 2021 |
| APPL NO | 17/183926 |
| CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 60/00188 (20200201) B60W 2556/45 (20200201) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1416 (20130101) H04L 63/1466 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20220265231 | Shi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xianbo Shi (Naperville, Illinois); Zhi Qiao (Darien, Illinois); Michael J. Wojcik (Orland Park, Illinois); Lahsen Assoufid (Chicago, Illinois) |
| ABSTRACT | Phase contrast and dark-field X-ray imaging enable imaging of objects that absorb or reflect very little X-ray light. Disclosed is a method and systems for performing coded-mask-based multi-contrast imaging (CMMI). The method includes providing radiation to a coded mask that has a known phase and absorption profile according to a pre-determined pattern. The radiation is then impingent upon a sample, and the radiation is detected to perform phase-reconstruction and image processing. The method and associated systems allow for the use of maximum-likelihood and machine learning methods for reconstruction images of the sample from the detected radiation. |
| FILED | Thursday, February 25, 2021 |
| APPL NO | 17/185387 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/40 (20130101) Original (OR) Class A61B 6/584 (20130101) Measurement of Nuclear or X-radiation G01T 1/295 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220266213 | Weissman |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Precision Combustion, Inc. (North Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeffrey G. Weissman (Guilford, Connecticut) |
| ABSTRACT | A solar reactor useful in reaction processes, more particularly, useful in endothermic reaction processes, such as a catalyzed process or an adsorption-desorption process. The reactor comprises a reaction pathway defined by an exterior wall and an interior wall, the exterior wall comprising a solar radiation receiver capable of converting solar radiation into heat and transmitting the heat to the reaction pathway. The reaction pathway has disposed therein, in alternating fashion, a plurality of reactive elements comprised of a catalyst or a sorbent and a plurality of heat transfer elements. |
| FILED | Monday, April 11, 2022 |
| APPL NO | 17/717907 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0053 (20130101) Original (OR) Class B01J 20/3441 (20130101) B01J 20/3483 (20130101) B01J 20/28045 (20130101) B01J 20/28095 (20130101) B01J 2208/065 (20130101) B01J 2219/00943 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220266239 | Bae et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chulsung Bae (Cohoes, New York); Eun Joo Park (Troy, New York); Sangtaik Noh (Troy, New York); Michael Pagels (Troy, New York) |
| ABSTRACT | The electrochemical energy conversion system of the present disclosure includes an anode, a cathode, and an ion exchange membrane including a polymer having an aromatic polymer chain and an alkylated substrate including an alkyl chain, and at least one ionic group. The alkylated substrate is bound to at least one aromatic group in the polymer chain via Friedel-Crafts alkylation of the at least one aromatic group. The alkylation reaction utilizes a haloalkylated tertiary alcohol or a haloalkylated alkene as a precursor. In the presence of an acid catalyst, a carbocation is generated in the precursor which reacts with the aromatic rings of the polymer chain. The at least one ionic group is then replaced with a desired cationic or anionic group using a substitution reaction. The membranes exhibit advantageous stability achieved through a simplified and scalable reaction scheme. |
| FILED | Friday, April 08, 2022 |
| APPL NO | 17/658627 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 39/20 (20130101) B01J 41/14 (20130101) Original (OR) Class Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/2287 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/1032 (20130101) H01M 8/1072 (20130101) H01M 2008/1095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220266326 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois); Shanghai Jiao Tong University (Shanghai, China PRC) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Huan Zhang (Shanghai, China PRC); Jian Cao (Wilmette, Illinois); Kornel Ehmann (Evanston, Illinois); Jun Chen (Shanghai, China PRC) |
| ABSTRACT | Flanges formed on sheet metal parts to increase the part stiffness or create mating surface for further assembly are created in an incremental sheet forming process using forming tool and supporting tool that move along a specified tool path so as to gradually deform a peripherally-clamped sheet metal work piece into the desired geometry. With two universal tools moving along the designed toolpath on the both sides of the part, the process is very flexible. Process time is can also be reduced by utilizing an accumulative double-sided incremental hole-flanging strategy, in which the flange is formed in only one step. |
| FILED | Friday, March 11, 2022 |
| APPL NO | 17/692832 |
| CURRENT CPC | Working or Processing of Sheet Metal or Metal Tubes, Rods or Profiles Without Essentially Removing Material; Punching Metal B21D 31/005 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220266332 | Jablonski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Department of Energy (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul D. Jablonski (Salem, Oregon); Jeffrey Hawk (Corvallis, Oregon); Martin Detrois (Salem, Oregon) |
| ABSTRACT | One or more embodiments relates to a method of casting a creep-resistant Ni-based superalloy and a homogenization heat treatment for the alloy, The method includes forming a feed stock having Nickel (Ni) and at least one of Chromium (Cr), Cobalt (Co), Aluminum (Al), Titanium (Ti), Niobium (Nb), Iron (Fe), Carbon (C), Manganese (Mn), Molybdenum (Mo), Silicon (Si), Copper (Cu), Phosphorus (P), Sulfur (S) and Boron (B). The method further includes fabricating the creep-resistant Ni-based superalloy in a predetermined shape using the feed stock and at least one process such as vacuum induction melting (VIM), electroslag remelting (ESR) and/or vacuum arc remelting (VAR). |
| FILED | Wednesday, February 24, 2021 |
| APPL NO | 17/184542 |
| CURRENT CPC | Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 18/06 (20130101) B22D 21/025 (20130101) B22D 25/06 (20130101) Original (OR) Class Alloys C22C 19/05 (20130101) C22C 2202/00 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/10 (20130101) Furnaces, Kilns, Ovens, or Retorts in General; Open Sintering or Like Apparatus F27B 14/10 (20130101) F27B 14/061 (20130101) F27B 2014/066 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267163 | Hagelin-Weaver et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Helena Hagelin-Weaver (Gainesville, Florida); Samantha Roberts (Hillsboro, Oregon); Nathan Carr (Bradenton, Florida) |
| ABSTRACT | The present disclosure provides for compositions, methods of making compositions, and methods of using the composition. In an aspect, the composition can be a reactive material that can be used to split a gas such as water or carbon dioxide. |
| FILED | Wednesday, April 27, 2022 |
| APPL NO | 17/730736 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 3/061 (20130101) Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 17/10 (20200101) C01F 17/241 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267211 | Fini et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Elham Fini (Phoenix, Arizona); Robert Allen (Golden, Colorado); Albert Hung (Tempe, Arizona); Matthew Green (Phoenix, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Elham Fini (Phoenix, Arizona); Robert Allen (Golden, Colorado); Albert Hung (Tempe, Arizona); Matthew Green (Phoenix, Arizona) |
| ABSTRACT | An asphalt modifier includes bitumen, polyolefin particles, and one or more alkyl terephthalamides. Preparing an asphalt modifier includes combining one or more alkyl terephthalamides, polyolefin particles, and bitumen, and dispersing the polyolefin particles in the bitumen to yield the asphalt modifier. Digesting polyethylene terephthalate includes combining polyethylene terephthalate with an alkylamine or carboxyalkylamine to yield a reaction mixture, and heating the reaction mixture to a temperature between about 20° C. and about 300° C. to yield an alkyl terephthalamide. |
| FILED | Friday, February 11, 2022 |
| APPL NO | 17/669779 |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 18/20 (20130101) C04B 24/124 (20130101) C04B 26/26 (20130101) Original (OR) Class Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 11/28 (20130101) C08J 2367/02 (20130101) C08J 2377/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267233 | Weissman |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PRECISION COMBUSTION, INC. (North Haven, Connecticut) |
| ASSIGNEE(S) | PRECISION COMBUSTION, INC. (North Haven, Connecticut) |
| INVENTOR(S) | Jeffrey Weissman (Guilford, Connecticut) |
| ABSTRACT | A process and apparatus for converting an alkane to an olefin. In one embodiment, the process involves oxidative coupling of an alkane, e.g., methane, with an oxidant, such as air, to produce an olefin having twice the number of carbon atoms as the alkane, e.g., ethylene. In another embodiment, the process involves oxidative dehydrogenation of an alkane, e.g., ethane, with an oxidant to form an olefin having the same number of carbon atoms as the alkane, e.g., ethylene. The process involves passing a flow of the oxidant from a first flow passage through a porous medium; diffusing a flow of the alkane from a second flow passage into the porous medium; and contacting the reactant alkane and the oxidant in the presence of a catalyst within the porous medium to produce the olefin. |
| FILED | Tuesday, May 10, 2022 |
| APPL NO | 17/741306 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 12/007 (20130101) B01J 19/249 (20130101) B01J 19/2415 (20130101) B01J 2219/2409 (20130101) Acyclic or Carbocyclic Compounds C07C 2/84 (20130101) Original (OR) Class C07C 5/333 (20130101) C07C 11/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267667 | Han et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jinkyu Han (San Ramon, California); Thomas Han (Livermore, California) |
| ABSTRACT | A product includes a cell having a mixture comprising a solvent and colloidal nanoparticles. Each of the colloidal nanoparticles have a core and a shell surrounding the core. The cell also includes at least one electrode. A product includes a nanoparticle having a core and a shell. The core includes a luminescent material. The shell is silicon-based. A method includes applying an external stimulus to a cell containing a mixture comprising a solvent and colloidal nanoparticles for altering the brightness and/or color of an assembly of at least some of the colloidal nanoparticles. Each of the colloidal nanoparticles have a core and a shell surrounding the core. |
| FILED | Tuesday, February 23, 2021 |
| APPL NO | 17/183007 |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/025 (20130101) Original (OR) Class C09K 11/7773 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/166 (20190101) G02F 2001/1678 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267802 | Weinberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President And Fellows Of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President And Fellows Of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Benjamin Weinberg (Cambridge, Massachusetts); Denitsa M. Milanova (Cambridge, Massachusetts); Issac Han (Cambridge, Massachusetts); George M. Church (Cambridge, Massachusetts) |
| ABSTRACT | Provided herein, in some embodiments, are methods and compositions for gene delivery. Provided herein is a technology for co-delivering to a cell (e.g., in vivo or ex vivo) enzymes capable of rearranging nucleic acid, such as site-specific recombinases, to directly assemble (e.g., covalently join) nucleic acid segments of, for example, a gene of interest. |
| FILED | Tuesday, July 14, 2020 |
| APPL NO | 17/627229 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/90 (20130101) C12N 15/8645 (20130101) Original (OR) Class C12N 2750/14143 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267913 | Nguyen-Phan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thuy-Duong Nguyen-Phan (Pittsburgh, Pennsylvania); Douglas R. Kauffman (Pittsburgh, Pennsylvania) |
| ABSTRACT | Three-dimensional (3D) hollow nanosphere electrocatalysts that convert CO2 into formate with high current density and Faradaic efficiency (FE). The SnO2 nanospheres were constructed from small, interconnected SnO2 nanocrystals. The size of the constituent SnO2 nanocrystals was controlled between 2-10 nm by varying the calcination temperature and observed a clear correlation between nanocrystal size and formate production. In situ Raman and time-dependent X-ray diffraction measurements confirmed that SnO2 nanocrystals were reduced to metallic Sn and resisted microparticle agglomeration during CO2 reduction. The nanosphere catalysts outperformed comparably sized, non-structured SnO2 nanoparticles and commercially-available SnO2 with a heterogeneous size distribution. |
| FILED | Wednesday, February 09, 2022 |
| APPL NO | 17/668061 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/07 (20210101) Original (OR) Class C25B 9/17 (20210101) C25B 11/042 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267916 | Zhao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Opus 12 Incorporated (Berkeley, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shuai Zhao (Santa Clara, California); Sichao Ma (Dublin, California); Edward Izett (Berkeley, California); Timothy A. Bekkedahl (Sunnyvale, California); Kendra P. Kuhl (Oakland, California) |
| ABSTRACT | Methods and/or systems for operating a carbon oxide reduction electrolyzer may involve (a) performing normal operation at the electrolyzer; (b) performing a recovery or protection process including: (i) applying a modified current and/or voltage to the electrolyzer, and (ii) while applying the reverse current to the electrolyzer, flowing a recovery gas to the cathode; and (c) resuming normal operation at the electrolyzer. Applying a modified current and/or voltage may involve applying a short circuit to the electrolyzer, holding the electrolyzer electrodes at open circuit voltage, and/or applying a reverse current to the electrolyzer. |
| FILED | Wednesday, February 23, 2022 |
| APPL NO | 17/652255 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/26 (20210101) C25B 9/19 (20210101) C25B 13/08 (20130101) C25B 15/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220268248 | Richerson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Transportation IP Holdings, LLC (Norwalk, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jay Richerson (Erie, Pennsylvania); Adam Edgar Klingbeil (Ballston Lake, New York); Eric Dillen (Erie, Pennsylvania); Kevin Bailey (Mercer, Pennsylvania); Kent Jeffries (Erie, Pennsylvania); Brett Heher (Pittsburgh, Pennsylvania); Manuel Licon Flores (Erie, Pennsylvania) |
| ABSTRACT | An alignment system includes an optical sensor device that may be inserted into a passage of a body that is located between a fuel injector and a combustion chamber of an engine cylinder. The body is shaped to transmit fuel ejected from a spray hole in a fuel injector into the combustion chamber of the engine cylinder. The system also includes a controller that may examine output of the optical sensor device and determine whether the passage of the body is aligned with the spray hole of the fuel injector based on the output from the optical sensor device. The controller may change a position of one or more of the body or the fuel injector responsive to determining that the passage of the body is not aligned with the spray hole of the fuel injector. |
| FILED | Monday, December 06, 2021 |
| APPL NO | 17/542966 |
| CURRENT CPC | Supplying Combustion Engines in General With Combustible Mixtures or Constituents Thereof F02M 65/00 (20130101) Original (OR) Class Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/272 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220268731 | AULT et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey); UT-BATTELLE, LLC (Oak Ridge, Tennessee); University of Hawaii (Honolulu, Hawaii) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jesse AULT (Knoxville, Tennessee); Sangwoo SHIN (Honolulu, Hawaii); Howard A. STONE (Princeton, New Jersey); Jie FENG (Princeton, New Jersey); Patrick WARREN (Wirral, United Kingdom) |
| ABSTRACT | Methods described herein, in some embodiments, permit extraction of particle structural and/or surface charge data from gradient induced particle motion in channels. In one aspect, a method of manipulating particle motion comprises introducing a fluid into a channel, the fluid comprising particles, and driving particle accumulation to a preselected location in the channel by setting advective velocity of the fluid to offset diffusiophoretic mobility of the particles at the preselected location. |
| FILED | Thursday, April 14, 2022 |
| APPL NO | 17/720687 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/00 (20130101) G01N 15/1456 (20130101) G01N 27/44721 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220268744 | Findikoglu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Chevron U.S.A. Inc. (San Ramon, California); Triad National Security, LLC (Los Alamos, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alp Tugrul Findikoglu (Los Alamos, California); Daniel Robert Chapman (San Ramon, California) |
| ABSTRACT | Combinations of multiple analytic techniques may be used to identify changes to a structure based on changes in characteristics of acoustic signals traveling along the structure. Acoustic signals traveling along the structure may be monitored to detect changes in characteristics of the acoustic signal from baseline signal characteristics. The changes in characteristics of the acoustic signals may be processed using multiple analytic techniques to provide analyses of the change in time-domain, in frequency-domain, and in mixed time-frequency-domain. The change to the structure may be identified based on a combination of the results of the analysis in time-domain, in frequency-domain, and in mixed time-frequency-domain. |
| FILED | Tuesday, June 18, 2019 |
| APPL NO | 17/620322 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/07 (20130101) G01N 29/12 (20130101) G01N 29/46 (20130101) G01N 29/50 (20130101) G01N 29/4427 (20130101) Original (OR) Class G01N 33/20 (20130101) G01N 2291/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220269535 | Basu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Arkaprava Basu (Bangalore, India); Joseph Lee Greathouse (Austin, Texas) |
| ABSTRACT | Systems, apparatuses, and methods for enforcing processor quality of service guarantees when servicing system service requests (SSRs) are disclosed. A system includes a first processor executing an operating system and a second processor executing an application which generates SSRs for the first processor to service. The first processor monitors the number of cycles spent servicing SSRs over a previous time interval, and if this number of cycles is above a threshold, the first processor starts delaying the servicing of subsequent SSRs. In one implementation, if the previous delay was non-zero, the first processor increases the delay used in the servicing of subsequent SSRs. If the number of cycles is less than or equal to the threshold, then the first processor services SSRs without delay. As the delay is increased, the second processor begins to stall and its SSR generation rate falls, reducing the load on the first processor. |
| FILED | Tuesday, March 01, 2022 |
| APPL NO | 17/684214 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/466 (20130101) G06F 9/4887 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220269558 | Sullivan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NVIDIA Corp. (Santa Clara, California) |
| ASSIGNEE(S) | NVIDIA Corp. (Santa Clara, California) |
| INVENTOR(S) | Michael Sullivan (Austin, Texas); Siva Kumar Sastry Hari (Sunnyvale, California); Brian Matthew Zimmer (Mountain View, California); Timothy Tsai (Santa Clara, California); Stephen W. Keckler (Austin, Texas) |
| ABSTRACT | An error reporting system utilizes a parity checker to receive data results from execution of an original instruction and a parity bit for the data. A decoder receives an error correcting code (ECC) for data resulting from execution of a shadow instruction of the original instruction, and data error correction is initiated on the original instruction result on condition of a mismatch between the parity bit and the original instruction result, and the decoder asserting a correctable error in the original instruction result. |
| FILED | Thursday, May 05, 2022 |
| APPL NO | 17/737374 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/30029 (20130101) G06F 9/30116 (20130101) G06F 11/102 (20130101) Original (OR) Class G06F 11/0772 (20130101) G06F 11/1044 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220270768 | Subhash et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ghatu Subhash (Gainesville, Florida); Ronald Howard Baney (Gainesville, Florida); James S. Tulenko (Gainesville, Florida); Edward Mckenna, III (Portland, Oregon); Lihao Ge (San Jose, California); Sunghwan Yeo (Gainesville, Florida) |
| ABSTRACT | Embodiments of the invention are directed to a method for production of a nuclear fuel pellet by spark plasma sintering (SPS), wherein a fuel pellet with more than 80% TD or more than 90% TD is formed. The SPS can be performed with the imposition of a controlled uniaxial pressure applied at the maximum temperature of the processing to achieve a very high density, in excess of 95% TD, at temperatures of 850 to 1600° C. The formation of a fuel pellet can be carried out in one hour or less. In an embodiment of the invention, a nuclear fuel pellet comprises UO2 and a highly thermally conductive material, such as SiC or diamond. |
| FILED | Tuesday, April 19, 2022 |
| APPL NO | 17/724017 |
| CURRENT CPC | Nuclear Reactors G21C 3/045 (20190101) G21C 3/62 (20130101) G21C 3/64 (20130101) Original (OR) Class G21C 21/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220270807 | Yao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yuan Yao (Tarrytown, New York); Todd Edward Takken (Brewster, New York); Andrew Ferencz (Southborough, Massachusetts); Xin Zhang (Chappaqua, New York); Liam Daley McAuliffe (Yorktown Heights, New York) |
| ABSTRACT | Embodiment of the present invention includes a magnetic structure and a magnetic structure used in a direct current (DC) to DC energy converter. The magnetic structure has an E-core and a plate, with the plate positioned in contact or in near contact with the post surfaces of the E-core. The E-core has a base, a no-winding leg, a transformer leg, and an inductor leg. The no-winding leg, the transformer leg, and the inductor leg are perpendicular and magnetically in contact with the base. The plate is a flat slab with lateral dimensions generally larger than its thickness. The plate has a plate nose that overlaps a top no-winding leg surface of the no-winding leg with a no-winding gap area to form a no-winding gap with a no-winding gap reluctance. The plate also has a plate end that overlaps a top inductor leg surface of the inductor leg with an inductor gap area to form an inductor gap with an inductor gap reluctance. In some embodiments, e.g., where the duty cycle is less than 50 percent, the inductor gap reluctance will be designed to be less than the no-winding gap reluctance. In these cases, the majority of the magnetic flux that passes through the transformer leg will return through the inductor leg, instead of through the no-winding leg. The inductor and no-winding gap reluctances can he adjusted, so that the electromotive force applied to a charge passing through the inductor will partially cancel the electromotive force applied by the transformer secondary. The gap reluctance ratio can be defined, so that the difference in secondary and inductor electromotive forces is equal to the output voltage defined by an optimal no-ripple duty cycle. In this way no changing current is required through the inductor to create a dI/dt inductive voltage drop across the output inductor. Zero output current ripple is achieved. Various embodiments of the plate, plate shape, and no-winding leg are disclosed. These embodiments allow achieving a high ratio of no-winding gap reluctance to inductor gap reluctance, for practical, affordable magnetic material structures and aspect ratios. A high gap reluctance ratio enables zero output current ripple for the high transformer turns ratios that are needed to achieve high input to output voltage ratios. The embodiments therefore allow achieving low output current ripple for 48 V or higher input voltages, 1 V or lower output voltages, and high output currents. |
| FILED | Friday, February 12, 2021 |
| APPL NO | 17/174453 |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/14733 (20130101) H01F 27/26 (20130101) Original (OR) Class H01F 27/28 (20130101) H01F 41/0206 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/33576 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220271186 | Yuan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yuan Yuan (Milpitas, California); Di Liang (Santa Barbara, California); Xiaoge Zeng (Milpitas, California); Zhihong Huang (Milpitas, California) |
| ABSTRACT | Examples described herein relate to an avalanche photodiode (APD) and an optical receiver including the APD. The APD may include a substrate and a photon absorption region disposed on the substrate. The substrate may include a charge carrier acceleration region under the photon absorption region; a charge region adjacent to the charge carrier acceleration region; and a charge carrier multiplication region adjacent to the charge region. The charge carrier acceleration region, the charge region, and the charge carrier multiplication region are laterally formed in the substrate. When a biasing voltage is applied to the optoelectronic device, photon-generated free charge carriers may be generated in the photon absorption region and are diffused into the charge carrier acceleration region. The charge carrier acceleration region is configured to accelerate the photon-generated free charge carriers prior to the photon-generated free charge carriers entering into the charge region and undergoing impact ionization in the charge carrier multiplication region. |
| FILED | Tuesday, February 23, 2021 |
| APPL NO | 17/249192 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0336 (20130101) H01L 31/1075 (20130101) Original (OR) Class H01L 31/02005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220271194 | ALBERI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); MicroLink Devices, Inc. (Niles, Illinois); South Dakota Board of Regents (Rapid City, South Dakota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kirstin ALBERI (Denver, Colorado); Christopher Leo STENDER (Glenview, Illinois); Scott Phillip AHRENKIEL (Golden, Colorado) |
| ABSTRACT | Described herein are optoelectronic devices and methods incorporating strain balanced direct bandgap AlxIn1-xP multiple quantum wells. The described devices are strain balanced in that the net strain between the ordered quantum wells and barriers is low, or in some cases zero. Advantageously, the described devices may be specifically designed for higher efficiency than existing AlxIn1-xP and may be grown on commercially available GaAs substrates. |
| FILED | Monday, February 21, 2022 |
| APPL NO | 17/651838 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/06 (20130101) H01L 33/0012 (20130101) H01L 33/12 (20130101) Original (OR) Class H01L 33/0025 (20130101) H01L 33/305 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220271235 | McGrath et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona, a body corporate (Tucson, Arizona); Southern University of Science and Technology (Shenzhen, Guangdong Province, China PRC) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of the University of Arizona, a body corporate (Tucson, Arizona); Southern University of Science and Technology (Shenzhen, Guangdong Province, China PRC) |
| INVENTOR(S) | Dominic V. McGrath (Tucson, Arizona); Zongxiang Xu (Shenzhen, Guangdon, China PRC); Neal R. Armstrong (Tucson, Arizona) |
| ABSTRACT | The present invention provides methods for increasing stability and efficiency of organic perovskite materials for use in various electronic devices. In particular, methods of the invention use a non-peripheral substituted phthalocyanine for passivating defects in organic perovskite materials, thereby increasing its stability and efficiency relative to the same material in the absence of said non-peripheral substituted phthalocyanine. |
| FILED | Thursday, July 23, 2020 |
| APPL NO | 17/629396 |
| CURRENT CPC | Heterocyclic Compounds C07D 487/22 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0072 (20130101) Original (OR) Class H01L 51/0078 (20130101) H01L 51/0092 (20130101) H01L 51/4246 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220271246 | Hou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shaocong Hou (Lu'An, China PRC); Stephen R. FORREST (Ann Arbor, Michigan) |
| ABSTRACT | An organic photovoltaic device comprises a substrate, a reflector positioned over the substrate, a first electrode positioned over at least a first portion of the reflector, a polaritonic antenna layer positioned over a second portion of the reflector different from the first portion, electrically connected to the first electrode, and at least one unit reaction cell positioned over at least part of the first electrode, the at least one unit reaction cell comprising a heterojunction layer comprising a donor material and an acceptor material, positioned over the first electrode, and a second electrode positioned over the heterojunction, wherein the polaritonic antenna and the reflector are configured to convert incoming photonic energy to polaritons. A method of fabricating an organic photovoltaic device is also disclosed. |
| FILED | Tuesday, February 08, 2022 |
| APPL NO | 17/666664 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0016 (20130101) H01L 51/0046 (20130101) H01L 51/441 (20130101) H01L 51/447 (20130101) Original (OR) Class H01L 51/4253 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220271260 | FORREST et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen R. FORREST (Ann Arbor, Michigan); Haonan Zhao (Ann Arbor, Michigan) |
| ABSTRACT | An organic light emitting device comprises an emissive layer stack having an anode side and a cathode side, comprising at least one emissive layer comprising an organic emissive material, an anode layer stack comprising at least one conductive layer, a cathode layer stack comprising at least one conductive layer, an anode-side reflector positioned on the anode side of the emissive layer stack, and a cathode-side reflector positioned on the cathode side of the emissive layer stack, wherein the anode-side reflector and the cathode side reflector are configured to form a resonant, electrically pumped cavity for ultrastrong coupling having a quality factor of at least 10. An electrically-pumped organic light emitting device is also disclosed. |
| FILED | Friday, January 21, 2022 |
| APPL NO | 17/581736 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/5218 (20130101) H01L 51/5265 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220271355 | Spangenberger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jeffrey S. Spangenberger (Naperville, Illinois); Bryant J. Polzin (Deerfield, Illinois); Jessica L. Durham (Braidwood, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Jeffrey S. Spangenberger (Naperville, Illinois); Bryant J. Polzin (Deerfield, Illinois); Jessica L. Durham (Braidwood, Illinois) |
| ABSTRACT | A method for producing clean black mass, anode or cathode for subsequent recycling is provided, the method comprising subjecting an intact battery to a shredding process to produce an aggregate, wherein the smallest particle generated is between 2.5 percent and 40 percent of original battery size. Also provided is a shredder for minimizing aggregation of whole batteries, the shredder comprising a shaft defining a longitudinal axis and a latitudinal axis; and a plurality of teeth disposed on said knives which fit on said shaft at an angle to the latitudinal axis selected from 15 degrees and 45 degrees, wherein the teeth have a first proximal end integrally molded to the shaft and a second free distal end. |
| FILED | Friday, February 19, 2021 |
| APPL NO | 17/180621 |
| CURRENT CPC | Crushing, Pulverising, or Disintegrating in General; Milling Grain B02C 18/08 (20130101) B02C 18/182 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/54 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220271493 | Kane |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Daniel J Kane (Santa Fe, New Mexico) |
| ASSIGNEE(S) | Mesa Photonics, LLC (Santa Fe, New Mexico) |
| INVENTOR(S) | Daniel J Kane (Santa Fe, New Mexico) |
| ABSTRACT | A pulse analysis system or method includes a frequency filter that receives an ultrafast pulse under test and disperses the pulse under test over a frequency range. The frequency filter separates the pulse under test into component frequency slices and provides the frequency slices to a detector coupled to a digitizer, which processes the digitized signal and collects a sonogram characteristic of the pulse under test. The frequency slices are arranged to overlap. Ptychography is performed on the sonogram to obtain characteristics of the pulse under test. |
| FILED | Thursday, May 05, 2022 |
| APPL NO | 17/737930 |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/11 (20130101) Original (OR) Class H01S 3/0057 (20130101) H01S 3/0078 (20130101) H01S 3/10023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20220266315 | Wettels et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ONROBOT LOS ANGELES INC. (Los Angeles, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicholas Wettels (Los Angeles, California); Asintha Nanayakkara (Woodland Hills, California); Patrick Marshall (Los Angeles, California) |
| ABSTRACT | Systems and methods are provided for an electroactuated adhesion system containing a dry adhesive material and at least two patterned electrodes. The two or more patterned electrodes may be capable of promoting or increasing adhesion of the electroactuated adhesion system while simultaneously preventing or mitigating the accumulation of dust, contaminants, or particulates on the surface of the adhesive material. |
| FILED | Wednesday, March 09, 2022 |
| APPL NO | 17/691000 |
| CURRENT CPC | Cleaning in General; Prevention of Fouling in General B08B 6/00 (20130101) Original (OR) Class Microstructural Devices or Systems, e.g Micromechanical Devices B81B 7/02 (20130101) B81B 2203/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220266338 | Firdosy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Samad A. Firdosy (La Crescenta, California); Robert P. Dillon (Long Beach, California); Ryan W. Conversano (Tarzana, California); John Paul C. Borgonia (Monrovia, California); Andrew A. Shapiro-Scharlotta (Glendale, California); Bryan W. McEnerney (Redondo Beach, California); Adam Herrmann (Piqua, Ohio) |
| ABSTRACT | Elements formed from magnetic materials and their methods of manufacture are presented. Magnetic materials include a magnetic alloy material, such as, for example, an Fe-Co alloy material (e.g., the Fe-Co-V alloy Hiperco-50(R)). The magnetic alloy materials may comprise a powdered material suitable for use in additive manufacturing techniques, such as, for example direct energy deposition or laser powder bed fusion. Manufacturing techniques include the use of variable deposition time and energy to control the magnetic and structural properties of the materials by altering the microstructure and residual stresses within the material. Manufacturing techniques also include post deposition processing, such as, for example, machining and heat treating. Heat treating may include a multi-step process during which the material is heated, held and then cooled in a series of controlled steps such that a specific history of stored internal energy is created within the material. Magnetic elements may include, for example, motors, generators, solenoids and swtiches, sensors, transformers, and hall thrusters, among other elements. |
| FILED | Monday, May 09, 2022 |
| APPL NO | 17/662617 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/20 (20210101) Original (OR) Class B22F 2003/248 (20130101) Alloys C22C 33/0207 (20130101) C22C 38/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267031 | CHOI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | SANG H. CHOI (Poquoson, Virginia); ROBERT W. MOSES (Poquoson, Virginia); DENNIS M. BUSHNELL (Hampton, Virginia) |
| ABSTRACT | The present disclosure is directed to a system including a nuclear thermal rocket or a nuclear reactor, at least one nuclear electric thruster coupled to the nuclear thermal rocket or the nuclear reactor, and a Nuclear Thermionic Avalanche Cell (NTAC) configured to generate electrical power. The NTAC cell may be positioned around a nuclear reactor core of the nuclear thermal rocket or the nuclear reactor, and the nuclear electric thruster may be powered by the NTAC generated electrical power. |
| FILED | Wednesday, December 29, 2021 |
| APPL NO | 17/564911 |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/408 (20130101) Original (OR) Class Producing a Reactive Propulsive Thrust, Not Otherwise Provided for F03H 1/0037 (20130101) Nuclear Power Plant G21D 5/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267034 | Warden et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOEING COMPANY (CHICAGO, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (CHICAGO, Illinois) |
| INVENTOR(S) | Harry Kendall Warden (Huntsville, Alabama); Jeffrey Wayne Weathers (Huntsville, Alabama); James Boyd Weathers (Huntsville, Alabama) |
| ABSTRACT | A collet assembly, for an umbilical plate that connects a vehicle to a ground station prior to a launch of the vehicle, includes an active decoupler. The active decoupler includes a pin. A cuff has a central opening. The pin passes through the central opening. A plurality of fingers are pivotally coupled to the cuff. A plurality of levers are pivotally coupled to the plurality of fingers and the pin. |
| FILED | Friday, January 07, 2022 |
| APPL NO | 17/647351 |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 5/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267140 | Chattopadhyay et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Goutam Chattopadhyay (Pasadena, California); Cecile D. Jung-Kubiak (Pasadena, California); Sofia Rahiminejad (Pasadena, California); Subash Khanal (Pasadena, California); Sven L. Van Berkel (Pasadena, California) |
| ABSTRACT | A phased array system comprising an array of antennas outputting or receiving electromagnetic radiation to or from a steerable direction, wherein the electromagnetic radiation is at submillimeter wavelengths. The system further comprises a plurality of waveguides outputting or receiving the signals to or from the antennas, each of the waveguides with individual phase tuning. The waveguides are configured and dimensioned to guide an electromagnetic wave comprising the signals having a frequency in a range of 100 gigahertz (GHz) to 1000 terahertz (THz). The system further comprises means for phase shifting the signal by means of shifting or varying one or more phases of the signals relative to one another so as to vary, steer, or scan a direction of the electromagnetic radiation. |
| FILED | Friday, February 18, 2022 |
| APPL NO | 17/675562 |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0018 (20130101) Original (OR) Class B81B 2207/053 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220268488 | Brewer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Blueshift, LLC dba Outward Technologies (Broomfield, Colorado) |
| ASSIGNEE(S) | Blueshift, LLC dba Outward Technologies (Broomfield, Colorado) |
| INVENTOR(S) | Andrew Timon Brewer (Wheat Ridge, Colorado); Ryan Garvey (Lafayette, Colorado) |
| ABSTRACT | A vertically oriented solar concentrator reactor system and method of use for high temperature thermochemical processes and/or electrical power generation. In one embodiment, the vertically oriented solar concentrator reactor system produces a thermochemical reaction of a stream of irradiated particles arranged concentrically with a concentrated light cone. In one aspect, the vertically oriented solar concentrator reactor system collects an irradiated particle stream within a hot particle containment vessel which communicates thermal energy to a heat exchanger, the heat exchanger in turn driving an electrical power generator. In one embodiment, the particles are a lunar regolith. |
| FILED | Tuesday, February 22, 2022 |
| APPL NO | 17/676919 |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/08 (20130101) Solar Heat Collectors; Solar Heat Systems F24S 20/20 (20180501) Original (OR) Class F24S 23/71 (20180501) F24S 80/20 (20180501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220269969 | Carrol et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Streamline Automation LLC (Huntsville, Alabama); Wake Forest University (Winston-Salem, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David L. Carrol (Winston Salem, North Carolina); Alton J. Reich (Huntsville, Alabama); Roberto Di Salvo (Cincinnati, Ohio) |
| ABSTRACT | A qubit device includes a crystal immobilized on a substrate and in contact with electrodes. The crystal exhibits a charge pair symmetry and with an electron current moving clockwise, counter clockwise, or both. The current in can be placed in a state of superposition wherein the current is unknown until it is measured, and the direction of the current is measured to produce a binary output corresponding to a logical zero or a logical one. A state of the qubit device is monitored by measuring a voltage, a current, or a magnetic field and assigning a superposition or base state depending on a threshold value. |
| FILED | Wednesday, October 21, 2020 |
| APPL NO | 17/635716 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/40 (20220101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/24 (20130101) H01L 29/423 (20130101) H01L 29/66977 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20220266005 | Sabiev et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anton Sabiev (Forest Hills, New York); WILLIAM BAUMAN (New Rochelle, New York); MARK KORSTEN (Hastings-on-Hudson, New York) |
| ABSTRACT | An iontophoresis system for positioning against skin of a subject is disclosed. The iontophoresis system can comprise at least one vessel having a solvent therein. An anode apparatus can couple to the at least one vessel. The anode apparatus can comprise a first reservoir configured to receive the solvent from the at least one vessel so that, when received into the first reservoir, the solvent makes contact with the skin of the subject, and a first electrode positioned above the first reservoir. A cathode apparatus can couple to the at least one vessel. The cathode apparatus can comprise a second reservoir configured to receive the solvent from the at least one vessel so that, when received into the first reservoir, the solvent makes contact with the skin of the subject, and a second electrode positioned above the second reservoir. |
| FILED | Wednesday, May 04, 2022 |
| APPL NO | 17/736602 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/30 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267312 | WALKER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Saint Louis University (St. Louis, Missouri); United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Saint Louis University (St. Louis, Missouri); United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | John K. WALKER (St. Louis, Missouri); Feng CAO (St. Louis, Missouri); Terri BOEHM (Ballwin, Missouri); Kinthada RAMAKUMAR (St. Louis, Missouri) |
| ABSTRACT | Provided herein are compounds of the formula: wherein the variables are as defined herein. Pharmaceutical compositions of the compounds are also provided. In some aspects, these compounds may be used for the treatment of diseases or disorders, such as an infection of an antibiotic resistant bacteria. |
| FILED | Wednesday, January 19, 2022 |
| APPL NO | 17/578616 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Heterocyclic Compounds C07D 417/04 (20130101) Original (OR) Class C07D 417/12 (20130101) C07D 417/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267381 | Boutjdir et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United State Government As Repesented By The Department of Veterans Affairs (Washington, District of Columbia); NEW YORK UNIVERSITY (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mohamed Boutjdir (Brooklyn, New York); Timothy Jude Cardozo (New York, New York) |
| ABSTRACT | Disclosed herein, are decoy peptides or polypeptides capable of neutralizing and/or inhibiting the binding of anti-Ro antibodies to a hERG potassium channel extracellular pore region, and pharmaceutical compositions containing the decoy peptides or polypeptides and methods of use. |
| FILED | Friday, August 21, 2020 |
| APPL NO | 17/637614 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) Peptides C07K 14/00 (20130101) Original (OR) Class C07K 16/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220270454 | Kishore et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States Government As Represented By The Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bellamkonda K. Kishore (Sandy, Utah); Yue Zhang (Salt Lake City, Utah); Noel G. Carlson (Salt Lake City, Utah) |
| ABSTRACT | Disclosed are the methods for treating kidney disease including autosomal dominant polycystic kidney disease (ADPKD) in a subject, comprising the step of administering to the subject a composition comprising a therapeutically effective amount of ticagrelor or a derivative thereof, treating ADPKD. Disclosed are methods of decreasing arginine vasopressin (AVP) production in a subject comprising the step of administering to the subject a composition comprising an effective amount of ticagrelor, thereby decreasing AVP production. Disclosed are methods for treating dilutional hyponatremia in a subject comprising the step of administering to the subject a composition comprising an effective amount of ticagrelor, thereby decreasing AVP production. |
| FILED | Monday, May 02, 2022 |
| APPL NO | 17/734232 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) A61K 31/519 (20130101) A61K 31/4365 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 13/12 (20180101) Aeroplanes; Helicopters B64C 39/024 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 13/196 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 7/185 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20220264876 | KLESSIG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH, INC. (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel KLESSIG (Dryden, New York); Murli MANOHAR (Ithaca, New York); Frank SCHROEDER (Ithaca, New York) |
| ABSTRACT | Compositions and methods for promoting, enhancing, and/or increasing plant growth are disclosed. |
| FILED | Wednesday, July 08, 2020 |
| APPL NO | 17/621927 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 3/04 (20130101) A01N 43/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220265808 | RAMAMOORTHY et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NDSU Research Foundation (Fargo, North Dakota); Biological Mimetics (Frederick, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sheela RAMAMOORTHY (Fargo, North Dakota); Peter NARA (Frederick, Maryland) |
| ABSTRACT | A PCV2 vaccine and a method of vaccinating against PCV2 are provided herein. The PCV2 vaccine includes a PCV2 infectious clone with a re-engineered PCV2 capsid in the backbone thereof, wherein the re-engineered PCV2 capsid includes a modified immunogenic region. The method of vaccinating against PCV2 includes administering the PCV2 vaccine including a PCV2 infectious clone with a re-engineered PCV2 capsid in the backbone thereof to a subject in need thereof. |
| FILED | Monday, July 27, 2020 |
| APPL NO | 17/628403 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/523 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220267740 | Schmitt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anthony Paul Schmitt (State College, Pennsylvania); Phuong Tieu Schmitt (State College, Pennsylvania); Greeshma Vivekananda Ray (Cleveland, Ohio) |
| ABSTRACT | Provided are modified virus-like particles (VLPs) of paramyxoviruses, compositions containing them, methods of using the VLPs for delivery of any particular protein of interest to any of a variety of cells, kits that contain expression vectors for making, using and detecting VLPs, and methods for screening for anti-viral compounds using the VLPs. The modified VLPs contain a contiguous recombinant polypeptide that contains i) all or a segment of a C-terminal domain of a paramyxovirus nucleocapsid protein and ii) a polypeptide sequence of a distinct protein. Non-covalent complexes of paramyxovirus M protein and fusion proteins that contain a C-terminal domain of a paramyxovirus nucleocapsid protein and a polypeptide sequence of a distinct protein are provided, as are non-covalent complexes of cells, and cell receptors, with modified VLPs. |
| FILED | Monday, April 18, 2022 |
| APPL NO | 17/723054 |
| CURRENT CPC | Peptides C07K 14/005 (20130101) C07K 14/8121 (20130101) C07K 16/1027 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 9/0069 (20130101) C12N 9/0089 (20130101) C12N 2760/18022 (20130101) C12N 2760/18023 (20130101) C12N 2760/18034 (20130101) C12N 2760/18222 (20130101) C12N 2760/18223 (20130101) C12N 2760/18234 (20130101) C12N 2760/18252 (20130101) C12N 2760/18722 (20130101) C12N 2760/18723 (20130101) C12N 2760/18734 (20130101) Enzymes C12Y 113/12005 (20130101) C12Y 115/01001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 20220268963 | LIN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Ning LIN (Princeton, New Jersey); Renzhi JING (Princeton, New Jersey) |
| ABSTRACT | According to various embodiments, a machine-learning based system for simulating tropical cyclones (TCs) and assessing TC risk is disclosed. The system includes a hierarchical Poisson genesis module configured to develop a Poisson regression and TC genesis simulation on a plurality of clustering grids. The system further includes an analog-wind track module configured to determine movement of a TC by both analog predictors formed by historical track patterns and current in situ wind. The system additionally includes a Markov intensity module configured to determine intensity change of the TC by considering three hidden discrete states of storm intensity change and associating each state with a probability distribution of intensity change. |
| FILED | Wednesday, July 29, 2020 |
| APPL NO | 17/629581 |
| CURRENT CPC | Meteorology G01W 1/10 (20130101) Original (OR) Class Electric Digital Data Processing G06F 30/10 (20200101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6277 (20130101) G06K 9/6297 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220269840 | Soles et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher L. Soles (Boyds, Maryland); Edwin Pak-Nin Chan (Rockville, Maryland); Irmgard Bischofberger (Chicago, Illinois); Sidney Robert Nagel (Chicago, Illinois); Heinrich Martin Jaeger (Chicago, Illinois); Juan Jose de Pablo (Chicago, Illinois); Nidhi Pashine (Chicago, Illinois); Daniel Robert Reid (Chicago, Illinois); Carl Goodrich (Chicago, Illinois); Andrea Jo-Wei Liu (Chicago, Illinois); Daniel Hexner (Chicago, Illinois); Marcos A. Reyes-Martinez (Washington, District of Columbia); Meng Shen (Los Angeles, California) |
| ABSTRACT | An inverse design machine for making a manufactured article that includes a designer Impact-mitigating architectured isotropic structure includes: an input unit that receives a primary structure; a primary structure analyzer that receives the primary structure from the input unit and determines primary properties of the primary structure; a structure adjuster that receives the primary properties from the primary structure analyzer, receives impact-mitigating properties from a structural property manager, and produces the designer Impact-mitigating architectured isotropic structure from the impact-mitigating properties; and the structural property manager that provides the impact-mitigating properties to the structure adjuster. |
| FILED | Thursday, April 28, 2022 |
| APPL NO | 17/731998 |
| CURRENT CPC | Electric Digital Data Processing G06F 30/17 (20200101) G06F 30/23 (20200101) Original (OR) Class G06F 2101/02 (20130101) G06F 2113/10 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220269966 | Gorshkov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexey Vyacheslavovich Gorshkov (Rockville, Maryland); Aniruddha Bapat (College Park, Maryland); Eddie Schoute (College Park, Maryland); Andrew Childs (Bethesda, Maryland) |
| ABSTRACT | Performing state reversal on a quantum spin chain includes: providing qubits in a quantum spin chain in an input state, such that the quantum spin chain includes: first and second terminal qubits and one or more intermediate qubits, such that: the qubits have a transverse field strength; the first and terminal qubits a longitudinal field strength; and nearest neighbor qubit pair has an Ising coupling strength; and evolving the quantum spin chain from the input state to a final state for an evolution period to perform state reversal on the quantum spin chain. |
| FILED | Friday, February 11, 2022 |
| APPL NO | 17/669946 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/20 (20220101) Original (OR) Class G06N 10/40 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 20220265955 | Jacobs et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Bryson Jacobs (Quaker Hill, Connecticut); Savannah Lyle (Saint Petersburg, Florida) |
| ABSTRACT | In an example, a ventilator includes a first container and a second container in fluidic communication with each other via a liquid. The second container includes a second container space surrounded by the second container and a second liquid surface. A hydrostatic pressure in the second container space results from a pressure differential defined by a difference between the first liquid surface elevation in the first container and the second liquid surface elevation. The second container space increases in size with an increase in the breathing gas supplied from a gas supply line to the second container space. An inhalation line is configured to open to permit a flow of the breathing gas from an inhalation inlet in the second container space to an inhalation outlet outside of the liquid and outside of the second container and coupled to a patient, causing the second container space to decrease in size. |
| FILED | Tuesday, May 10, 2022 |
| APPL NO | 17/741081 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/0003 (20140204) A61M 16/16 (20130101) Original (OR) Class A61M 16/208 (20130101) A61M 2205/3348 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
| US 20220270712 | Grgicak et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey); National University of Ireland Maynooth, Maynooth University (Maynooth, Ireland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Catherine M. Grgicak (New Brunswick, New Jersey); Desmond S. Lun (New Brunswick, New Jersey); Kenneth R. Duffy (Dublin, Ireland) |
| ABSTRACT | Systems and methods of the present disclosure enable automated analyses of a biological sample using a processing system by receiving signal profiles of each allele of a set of cells in the sample. A set of allele vectors are determined based on a mapping of the magnitude of the measurement of each signal profile at each locus to an index location. A set of cell vectors is generated by concatenating each allele vector of each cell. A cluster model is utilized to generate clusters of the signal profiles based on the set of cell vectors to represent contributors. A first likelihood of a target contributor matching a contributor and a second likelihood of the target contributor not matching any contributor are determined by comparing the target signal profile to each cluster. A likelihood ratio is determined from a ratio of the first likelihood and the second likelihood. |
| FILED | Friday, February 11, 2022 |
| APPL NO | 17/669790 |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/20 (20190201) G16B 20/20 (20190201) G16B 30/00 (20190201) G16B 40/30 (20190201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of State (DOS)
| US 20220267806 | Jin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Shengkan Jin (Belle Mead, New Jersey); Juan-Carlos Collantes (Princeton, New Jersey) |
| ABSTRACT | The present invention discloses a system for targeted gene editing and related uses. |
| FILED | Monday, April 25, 2022 |
| APPL NO | 17/660523 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/102 (20130101) C12N 15/902 (20130101) Original (OR) Class C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 20220270807 | Yao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yuan Yao (Tarrytown, New York); Todd Edward Takken (Brewster, New York); Andrew Ferencz (Southborough, Massachusetts); Xin Zhang (Chappaqua, New York); Liam Daley McAuliffe (Yorktown Heights, New York) |
| ABSTRACT | Embodiment of the present invention includes a magnetic structure and a magnetic structure used in a direct current (DC) to DC energy converter. The magnetic structure has an E-core and a plate, with the plate positioned in contact or in near contact with the post surfaces of the E-core. The E-core has a base, a no-winding leg, a transformer leg, and an inductor leg. The no-winding leg, the transformer leg, and the inductor leg are perpendicular and magnetically in contact with the base. The plate is a flat slab with lateral dimensions generally larger than its thickness. The plate has a plate nose that overlaps a top no-winding leg surface of the no-winding leg with a no-winding gap area to form a no-winding gap with a no-winding gap reluctance. The plate also has a plate end that overlaps a top inductor leg surface of the inductor leg with an inductor gap area to form an inductor gap with an inductor gap reluctance. In some embodiments, e.g., where the duty cycle is less than 50 percent, the inductor gap reluctance will be designed to be less than the no-winding gap reluctance. In these cases, the majority of the magnetic flux that passes through the transformer leg will return through the inductor leg, instead of through the no-winding leg. The inductor and no-winding gap reluctances can he adjusted, so that the electromotive force applied to a charge passing through the inductor will partially cancel the electromotive force applied by the transformer secondary. The gap reluctance ratio can be defined, so that the difference in secondary and inductor electromotive forces is equal to the output voltage defined by an optimal no-ripple duty cycle. In this way no changing current is required through the inductor to create a dI/dt inductive voltage drop across the output inductor. Zero output current ripple is achieved. Various embodiments of the plate, plate shape, and no-winding leg are disclosed. These embodiments allow achieving a high ratio of no-winding gap reluctance to inductor gap reluctance, for practical, affordable magnetic material structures and aspect ratios. A high gap reluctance ratio enables zero output current ripple for the high transformer turns ratios that are needed to achieve high input to output voltage ratios. The embodiments therefore allow achieving low output current ripple for 48 V or higher input voltages, 1 V or lower output voltages, and high output currents. |
| FILED | Friday, February 12, 2021 |
| APPL NO | 17/174453 |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/14733 (20130101) H01F 27/26 (20130101) Original (OR) Class H01F 27/28 (20130101) H01F 41/0206 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/33576 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 20220268518 | Chudnovsky et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UTILIZATION TECHNOLOGY DEVELOPMENT, NFP (Des Plaines, Illinois) |
| ASSIGNEE(S) | UTILIZATION TECHNOLOGY DEVELOPMENT, NFP (Des Plaines, Illinois) |
| INVENTOR(S) | Yaroslav Chudnovsky (Skokie, Israel); Dmytro Buyadgie (Pleasant Hill, California); Olexiy Buyadgie (Clayton, California); Oleksii Drakhnia (Pleasant Hill, California) |
| ABSTRACT | Methods and systems for the thermo-vacuum drying and processing of objects such as clothes. A vacuum ejector driven by high-pressure steam is employed to evacuate evaporated moisture mixed with air from a dryer vessel producing an intensification of the drying process such as can significantly reduce the energy and time requirements for the drying process and increase water utilization. |
| FILED | Tuesday, March 01, 2022 |
| APPL NO | 17/683748 |
| CURRENT CPC | Laundering, Drying, Ironing, Pressing or Folding Textile Articles D06F 58/26 (20130101) Drying Solid Materials or Objects by Removing Liquid Therefrom F26B 5/042 (20130101) Original (OR) Class F26B 23/004 (20130101) F26B 23/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 20220268166 | Chuong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Conway Chuong (Manchester, Connecticut); Jeremy K. Paskind (Glastonbury, Connecticut); Shane R. Sylvester (Cromwell, Connecticut) |
| ABSTRACT | A seal assembly, including: a seal, the seal having; a support ring, a shoe, and a beam extending between the shoe and the support ring, wherein the shoe moves relative to the support ring via the beam; a spacer and a second seal; a seal ring; a carrier ring, the second seal being located adjacent to one end of the shoe and the seal ring being located adjacent to an opposite end of the shoe and the carrier ring extends from the seal ring to the spacer, the carrier ring being adjacent to the support ring of the seal; and a wear resistant coating located between a surface of the seal ring and an opposite end of the shoe. |
| FILED | Friday, February 19, 2021 |
| APPL NO | 17/179645 |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/003 (20130101) Original (OR) Class F01D 11/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220268167 | Farmer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathon Farmer (Newport, Kentucky); Ricardo Caraballo (Maineville, Ohio) |
| ABSTRACT | A sealing apparatus for an axial flow turbomachine is disclosed. An example axial flow turbomachine includes band segments bordering a flow path, a first spline seal disposed at a first angle within a first slot of the band segments, a second spline seal disposed at second angle within a second slot of the band segments, a Z-seal disposed across a gap between the first slot and the second, the Z-seal positioned at least partially within the first slot and the second slot. The Z-seal includes a first segment disposed at the first angle at least partially within the first slot, the first segment to contact the first spline seal, a second segment disposed at the second angle at least partially within the second slot, a portion of the second segment in connection with a portion of the first segment, the second segment to contact the second spline seal. |
| FILED | Monday, February 22, 2021 |
| APPL NO | 17/181765 |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/02 (20130101) F01D 11/005 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/06 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/55 (20130101) F05D 2240/128 (20130101) F05D 2250/75 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220268735 | Sheldon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paul D. Sheldon (Lynchburg, Virginia); Wayne M. Latham (Forest, Virginia); Thomas C. Mohr (Forest, Virginia); Aaron C. Havener (Pittsburgh, Pennsylvania); Richard Manzini (Pittsburg, Pennsylvania); Timothy A. Policke (Forest, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul D. Sheldon (Lynchburg, Virginia); Wayne M. Latham (Forest, Virginia); Thomas C. Mohr (Forest, Virginia); Aaron C. Havener (Pittsburgh, Pennsylvania); Richard Manzini (Pittsburg, Pennsylvania); Timothy A. Policke (Forest, Virginia) |
| ABSTRACT | A method of inspecting a material includes examining a surface of a test material with an eddy current sensor and applying an X-ray fluorescence analysis to the surface of the test material at the same location at which the eddy current examination was performed. |
| FILED | Thursday, December 23, 2021 |
| APPL NO | 17/561647 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/223 (20130101) G01N 27/9046 (20130101) Original (OR) Class G01N 27/9073 (20130101) G01N 2223/076 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, August 25, 2022.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-applications-20220825.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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