FedInvent™ Patent Applications
Application Details for Thursday, October 20, 2022
This page was updated on Monday, October 24, 2022 at 03:47 PM GMT
Department of Health and Human Services (HHS)
| US 20220330543 | Toner et al. |
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| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mehmet Toner (Charlestown, Massachusetts); Lindong Weng (Arlington, Massachusetts); Reinier Johan De Vries (Boston, Massachusetts); Shannon N. Tessier (Framingham, Massachusetts); Mustafa Uygun (Newton, Massachusetts) |
| ABSTRACT | The present disclosure provides methods for bulk droplet vitrification of cells, compositions including the vitrified droplets, and systems for performing the methods for bulk droplet vitrification cells. |
| FILED | Monday, December 02, 2019 |
| APPL NO | 17/632322 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0221 (20130101) A01N 1/0252 (20130101) A01N 1/0284 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220330792 | Barton et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tuscon, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jennifer Barton (Tucson, Arizona); Kelli Kiekens (Tucson, Arizona); Gabriella Romano (Tempe, Arizona); Swati Chandra (Tucson, Arizona); Steven Santaniello (Tucson, Arizona); Richard Cordova (Tucson, Arizona); David Vega (Tucson, Arizona) |
| ABSTRACT | A falloposcope is described, and a method of screening a patient for fallopian tube and/or ovarian cancer with the falloposcope. The falloposcope can perform optical imaging, including fluorescence imaging and/or optical coherence tomography (OCT), and optionally include a channel for a sampling wire, within a diameter of about 0.7 millimeter. The method includes inserting the falloposcope through a lumen of vagina, cervix, uterus, and fallopian tube so a tip of the falloposcope is in proximity to a first fallopian tube or ovary of the patient; providing fluorescence stimulus wavelength through an illumination fiber of the falloposcope while imaging light at fluorescence emission wavelength through a coherent fiber bundle to form fluorescence emissions images; and determining suspect tissue. Then the sampling wire is used to collect cells from the suspect tissue for karyotype and other analysis. |
| FILED | Wednesday, September 09, 2020 |
| APPL NO | 17/753578 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/05 (20130101) A61B 1/07 (20130101) A61B 1/0057 (20130101) A61B 1/00082 (20130101) A61B 1/00096 (20130101) Original (OR) Class A61B 1/0638 (20130101) A61B 10/04 (20130101) A61B 10/0291 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220330804 | Shi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Dartmouth-Hitchcock Clinic (Lebanon, New Hampshire); The Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yuan Shi (Hanover, New Hampshire); Xiaotian Wu (East Greenwich, Rhode Island); Joseph A. Paydarfar (Hanover, New Hampshire); Ryan J. Halter (Orford, New Hampshire) |
| ABSTRACT | A support rig for a medical instrument can hold a medical instrument that is inserted into a patient in a fixed position and orientation relative to patient, so that the position and orientation of the medical instrument is not affected by the breathing or other motion of the patient. The support rig and medical instrument can be radiolucent and non-metallic, so that an image can be taken of the patient while the medical instrument is inserted in the patent and held by the support rig. The radiolucent support rig and medical instrument can allow for imaging, including x-ray, CT, and/or MRI, to occur simultaneously during the surgery. Surgical outcomes can be improved by using imaging to provide information about a tumor and/or anatomical structures during surgery. |
| FILED | Tuesday, March 08, 2022 |
| APPL NO | 17/689924 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/24 (20130101) Original (OR) Class A61B 1/267 (20130101) A61B 6/44 (20130101) A61B 6/145 (20130101) A61B 17/0293 (20130101) A61B 34/30 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220330817 | Yates et al. |
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| FUNDED BY |
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| APPLICANT(S) | Retivue, LLC (Charlottesville, Virginia) |
| ASSIGNEE(S) | Retivue, LLC (Charlottesville, Virginia) |
| INVENTOR(S) | Paul Andrew Yates (Charlottesville, Virginia); Viatcheslav Orlov (Henrico, Virginia) |
| ABSTRACT | Speculums and spacers are used to position a retinal camera to obtain images of a fundus of an eye. In some instances, the speculums and spacers are designed to contact the eye to prevent rotation of the eye during imaging. In other instances, no contact is made with the eye. A light source may include visible light or limited to infrared light. |
| FILED | Monday, April 18, 2022 |
| APPL NO | 17/659597 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/14 (20130101) A61B 3/1208 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220330832 | Yang et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Fan Yang (Redwood City, California); Zihao Ou (Redwood City, California); Guosong Hong (Cambridge, Massachusetts); Xiang Wu (Redwood City, California); Paul Chong (Palo Alto, California); Huiliang Wang (Redwood City, California); Xingjun Zhu (Shanghai, China PRC) |
| ABSTRACT | Provided are methods of contacting a tissue inside a subject with light by applying an ultrasound signal to a photoexcited mechanoluminescent particle while the mechanoluminescent particle is inside the subject and in proximity to the tissue, thereby causing the mechanoluminescent particle to emit light that contacts the tissue. Provided are systems and kits for performing such methods. |
| FILED | Wednesday, November 25, 2020 |
| APPL NO | 17/642648 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0097 (20130101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 41/0057 (20130101) A61K 49/0093 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220330913 | Fleischman |
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| FUNDED BY |
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| APPLICANT(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aaron Fleischman (Beachwood, Ohio) |
| ABSTRACT | High-resolution intravascular ultrasound (H-IVUS) operates under a large acoustic bandwidth, provides high resolution while maintaining good depth penetration, and exhibits other favorable characteristics like focused imaging. A H-IVUS transducer assembly can be manufactured at a low cost using conventional methods commonly utilized in the microelectronics industry. The H-IVUS transducer assembly can include a printed circuit having one or more electrical signal conditioners. One or more convertors made of a polymer and configured to convert electrical energy to acoustic energy and acoustic energy to electrical energy can be formed in place away from the printed circuit. After construction, the one or more formed in place convertors are interfaced to the printed circuit with at least a conductive material. |
| FILED | Thursday, April 07, 2022 |
| APPL NO | 17/715556 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0066 (20130101) A61B 5/02007 (20130101) A61B 8/12 (20130101) Original (OR) Class A61B 8/4483 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220330982 | Stoianovici et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dan Stoianovici (Reisterstown, Maryland); Doru Petrisor (Lutherville, Maryland) |
| ABSTRACT | An embodiment in accordance with the present invention provides a robot structure that includes an MM-Safe pneumatic stepper motor and optical encoding technologies. The present invention includes a needle guide and a needle depth limiter. The needle for biopsy is inserted through the needle guide and the depth of inserting is limited by the needle depth limiter. The robot is configured to control this procedure. The robot structure is adapted for biopsy, a novel way of setting the depth of needle insertion, image-to-robot registration. The system includes control for the robot. |
| FILED | Thursday, June 30, 2022 |
| APPL NO | 17/855428 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 10/0233 (20130101) A61B 17/3403 (20130101) A61B 17/3494 (20130101) Original (OR) Class A61B 34/30 (20160201) A61B 50/30 (20160201) A61B 90/03 (20160201) A61B 90/08 (20160201) A61B 90/11 (20160201) A61B 90/37 (20160201) A61B 2017/3409 (20130101) A61B 2050/314 (20160201) A61B 2090/034 (20160201) A61B 2090/374 (20160201) A61B 2090/0813 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220331224 | Hwang et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Geelsu Hwang (Philadelphia, Pennsylvania); Hye-Eun Kim (Philadelphia, Pennsylvania); Atul Dhall (Philadelphia, Pennsylvania) |
| ABSTRACT | The disclosed subject matter provides compositions and methods for treating dental caries. The composition can include an effective amount of a mannan degrading enzyme. The effective amount of the mannan degrading enzyme can be present to treat dental caries of a subject. |
| FILED | Tuesday, April 12, 2022 |
| APPL NO | 17/718922 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/66 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/02 (20180101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 11/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2488 (20130101) Enzymes C12Y 302/01024 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220331249 | Konduri et al. |
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| FUNDED BY |
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| APPLICANT(S) | VGSK Techologies, Inc. (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kameswari Konduri (Stoneham, Massachusetts); Nejat Duzgunes (Mill Valley, California); Jogi Pattisapu (Orlando, Florida); Ram Pattisapu (Silverthorne, Colorado) |
| ABSTRACT | Disclosed herein are pharmaceutical compositions and methods for oral, sublingual or subcutaneous administration comprising a sterically stabilized liposome carrier comprising: i) poly (ethylene glycol) distearoylphosphatidylethanolamine (PEG-DSPE); and ii) at least one of phosphatidylglycerol and phosphatidylcholine. Compositions and methods for treatment of food allergy and eosinophilic esophagitis are also described. |
| FILED | Friday, January 07, 2022 |
| APPL NO | 17/571049 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 9/1271 (20130101) Original (OR) Class A61K 31/58 (20130101) A61K 31/573 (20130101) A61K 45/06 (20130101) A61K 47/34 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) A61P 31/06 (20180101) A61P 37/08 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220331267 | PAHAN et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rush University Medical Center (Chicago, Illinois) |
| ASSIGNEE(S) | Rush University Medical Center (Chicago, Illinois) |
| INVENTOR(S) | Kalipada PAHAN (Skokie, Illinois); Avik ROY (Chicago, Illinois) |
| ABSTRACT | Methods of modulating peroxisome proliterator-activated receptor β (PPARβ) activity in a cell in a subject in need thereof are provided. The methods include administering an effective amount of a PPAPβ ligand to the subject where the PPAPβ ligand is selected from 1,3-Di-tertbutyl benzene (DBB), 2,4-Di-tertbutyl phenol (DBP), Methyl palmitate (MePA), 2,6-Di-tertbutyl-4-Methyl Phenol (DBMP), 3,4-Di-tertbutyl-Phenol (3,4-DBP), 2,3-Di-tertbutyl-Phenol (2,3-DBP), and 2,6-Di-tertbutyl-Phenol (2,6-DBP). |
| FILED | Wednesday, September 02, 2020 |
| APPL NO | 17/640698 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/167 (20130101) A61K 9/7038 (20130101) A61K 31/05 (20130101) Original (OR) Class A61K 31/015 (20130101) A61K 31/21 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220331273 | RAHBAR et al. |
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| FUNDED BY |
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| APPLICANT(S) | CITY OF HOPE (Duarte, California) |
| ASSIGNEE(S) | CITY OF HOPE (Duarte, California) |
| INVENTOR(S) | Samuel RAHBAR (Beverly Hills, California); Timothy W. SYNOLD (Monrovia, California); John TERMINI (Altadena, California); Gerald WUENSCHELL (Duarte, California); Daniel TAMAE (Duarte, California); Sarah SHUCK (Orange, California) |
| ABSTRACT | Methods of quantifying a N2-(1-carboxyethyl)-2′-deoxyguanosine (CEdG) levels in biological samples and comparing those levels to known normal levels can diagnose a number of metabolic disorders or complications associated therewith, including diabetes, its associated complications, and cancer. Methods can also determine whether therapies for disorders are effective by measuring CEdG levels before and after treatment. Measurement of CEdG levels is achieved by using liquid chromatography electrospray ionization tandem mass spectrometry. |
| FILED | Monday, November 22, 2021 |
| APPL NO | 17/532928 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/195 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/7233 (20130101) G01N 30/7266 (20130101) G01N 33/6893 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220331293 | TANG et al. |
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| FUNDED BY |
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| APPLICANT(S) | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida); The United States of America, as represented by the Secretary, Department of Health and Human Servic (Bethesda, Maryland); THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hengli TANG (Tallahassee, Florida); Emily M. LEE (Tallahassee, Florida); Wei ZHENG (Rockville, Maryland); Ruili HUANG (Rockville, Maryland); Miao XU (Rockville, Maryland); Wenwei HUANG (Rockville, Maryland); Khalida SHAMIM (Rockville, Maryland); Guoli MING (Philadelphia, Pennsylvania); Hongjun SONG (Philadelphia, Pennsylvania) |
| ABSTRACT | The present invention concerns the use of compounds and compositions for the treatment or prevention of Flavivirus infections, such as dengue virus infections and Zika virus infections. Aspects of the invention include methods for treating or preventing Flavivirus virus infection, such as dengue virus and Zika virus infection, by administering a compound or composition of the invention, to a subject in need thereof; methods for inhibiting Flavivirus infections, such as dengue virus and Zika virus infections, in a cell in vitro or in vivo; pharmaceutical compositions; packaged dosage formulations; and kits useful for treating or preventing Flavivirus infections, such as dengue virus and Zika virus infections. |
| FILED | Tuesday, June 28, 2022 |
| APPL NO | 17/809345 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/165 (20130101) A61K 31/245 (20130101) A61K 31/336 (20130101) A61K 31/352 (20130101) A61K 31/422 (20130101) A61K 31/427 (20130101) A61K 31/433 (20130101) A61K 31/506 (20130101) A61K 31/517 (20130101) A61K 31/519 (20130101) A61K 31/554 (20130101) A61K 31/4162 (20130101) A61K 31/4184 (20130101) Original (OR) Class A61K 31/4535 (20130101) A61K 31/4709 (20130101) A61K 31/4741 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220331301 | Cebotaru |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
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| INVENTOR(S) | Liudmila Cebotaru (Baltimore, Maryland) |
| ABSTRACT | Cystic fibrosis transmembrane conductance regulator (CFTR) modulators rescue several processes malfunctioning in autosomal recessive polycystic kidney disease (ARPKD), including increasing FPC and CFTR protein levels, increasing CFTR at the basolateral membrane and at the cilia, reducing cAMP, reducing ER Ca2+ release in response to thapsigargin, and reducing Hsp70, Hsp90, and Aha1. CFTR modulators also correct the trafficking of CFTR. All these maneuvers, either individually or in combination, reduce cyst growth in liver and improve liver, renal, pancreatic and lung function. |
| FILED | Thursday, February 17, 2022 |
| APPL NO | 17/674090 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) A61K 31/352 (20130101) A61K 31/443 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 13/12 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220331329 | SHAPIRO et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Maryland, Baltimore (Baltimore, Maryland); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul S. SHAPIRO (Baltimore, Maryland); Alexander D. MACKERELL, JR. (Baltimore, Maryland); Jeffrey D. HASDAY (Timonium, Maryland) |
| ABSTRACT | Compounds that inhibit p38α MAPK protein, and methods of using the same, are provided for treating or preventing diseases such as cancer or inflammatory diseases. |
| FILED | Monday, May 09, 2022 |
| APPL NO | 17/740248 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/54 (20130101) A61K 31/5375 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/02 (20180101) A61P 29/00 (20180101) A61P 31/00 (20180101) A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220331357 | LIDDLE et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
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| INVENTOR(S) | Rodger LIDDLE (Durham, North Carolina); Ahmad FAROOQ (Durham, North Carolina) |
| ABSTRACT | The present disclosure provides compositions comprising sodium phosphate for the prevention and treatment of pancreatitis and methods of using same. |
| FILED | Monday, September 28, 2020 |
| APPL NO | 17/763740 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/444 (20130101) A61K 33/06 (20130101) A61K 33/42 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/18 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220331360 | Leonard et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Warren J. Leonard (Bethesda, Maryland); Dalton J. Hermans (Manitowoc, Wisconsin); Luca Gattinoni (Washington, District of Columbia); Leonard M. Neckers (Bethesda, Maryland); Sanjivan Gautam (Rockville, Maryland) |
| ABSTRACT | The invention provides compositions and methods for using adoptive cell therapy (ACT) for treating cancer in a mammal. Cultured T-cells are provided by (a) obtaining an isolated population of T cells, and (b) culturing the isolated T cells ex vivo in the presence of a cytokine and a lactate dehydrogenase inhibitor. The cultured T-cells then can be administered to the mammal |
| FILED | Thursday, August 06, 2020 |
| APPL NO | 17/633414 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220331365 | Zhang et al. |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Liangfang Zhang (La Jolla, California); Ronnie H. Fang (La Jolla, California); Jia Zhuang (La Jolla, California); Weiwei Gao (La Jolla, California) |
| ABSTRACT | A biomimetic oxygen delivery carrier is provided by employing natural cell membrane as a stabilizer for fluorocarbon nanoemulsions. The resulting formulation exhibits a high capacity for delivering oxygen and can be used to successfully resuscitate subjects in need due to for example hemorrhagic shock. This natural-synthetic platform can alleviate the impact of blood shortages in clinical settings among other uses. |
| FILED | Tuesday, September 01, 2020 |
| APPL NO | 17/639895 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 31/02 (20130101) A61K 35/18 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220331382 | Hatfull et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Graham F. Hatfull (Pittsburgh, Pennsylvania); Carlos Andrés Guerrero (Pittsburgh, Pennsylvania); Rebekah Marie Dedrick (Pittsburgh, Pennsylvania) |
| ABSTRACT | Disclosed are pharmaceutical compositions comprising a combination of five or more phages and a pharmaceutically acceptable carrier, as well as methods of treating, reducing, or preventing a disease caused by Mycobacterium tuberculosis in a mammal, methods of treating an antibiotic resistant infection in a mammal, and methods of treating, reducing, or preventing activation of a latent disease caused by M. tuberculosis. |
| FILED | Friday, April 08, 2022 |
| APPL NO | 17/716939 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0073 (20130101) A61K 35/76 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220331390 | DENIS et al. |
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| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Gerald V. DENIS (Arlington, Massachusetts); Louis C. GERSTENFELD (Canton, Massachusetts); Naser JAFARI (Boston, Massachusetts); Tova MESHULAM (Boston, Massachusetts) |
| ABSTRACT | The technology described herein is directed to methods of treating and diagnosing cancer, e.g, by measuring the expression of certain genes in exosomes. |
| FILED | Wednesday, April 06, 2022 |
| APPL NO | 17/714295 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/005 (20130101) Original (OR) Class A61K 38/217 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220331401 | Sweet-Cordero et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eric Alejandro Sweet-Cordero (San Francisco, California); Jennifer R. Cochran (Stanford, California); Jun Woo Kim (Mountain View, California); Cesar P. Marquez (Stanford, California) |
| ABSTRACT | Provided are methods of treating a KRAS mutant cancer in an individual. In certain embodiments, the methods include administering to an individual identified as having a KRAS mutant cancer a therapeutically effective amount of an agent that inhibits cardiotrophin-like cytokine factor 1 (CLCF1)-ciliary neurotrophic factor receptor (CNTFR) signaling. According to some embodiments, the KRAS mutant cancer is a KRAS mutant lung cancer, such as a KRAS mutant non-small cell lung cancer (NSCLC), e.g., a KRAS mutant lung adenocarcinoma (LUAD). Also provided are kits that find use, e.g., in practicing the methods of the present disclosure. |
| FILED | Thursday, September 10, 2020 |
| APPL NO | 17/639525 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/19 (20130101) A61K 38/1793 (20130101) Original (OR) Class A61K 47/60 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220331403 | BOSS |
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| FUNDED BY |
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| APPLICANT(S) | ENERGESIS PHARMACEUTICALS, INC. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | OLIVIER D. BOSS (BOSTON, Massachusetts) |
| ABSTRACT | This disclosure relates to compositions and methods for recruiting brown adipocytes in vitro and in vivo from brown adipocyte progenitor cells found in human skeletal muscle. Methods for treating metabolic disease are also provided. Additionally, methods for treating hypothermia are provided. In some embodiments, the brown adipocyte recruiter is a human protein or peptide. In other embodiments the brown adipocyte recruiter may be a non-human protein or peptide. In still other embodiments, the brown adipocyte recruiter is a small molecule or natural product. |
| FILED | Thursday, June 30, 2022 |
| APPL NO | 17/853992 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/165 (20130101) A61K 31/166 (20130101) A61K 31/353 (20130101) A61K 31/426 (20130101) A61K 31/506 (20130101) A61K 31/4745 (20130101) A61K 31/5415 (20130101) A61K 31/5575 (20130101) A61K 38/22 (20130101) A61K 38/105 (20130101) A61K 38/185 (20130101) A61K 38/195 (20130101) A61K 38/204 (20130101) A61K 38/1825 (20130101) Original (OR) Class A61K 38/2278 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220331415 | BUTTE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Manish J. BUTTE (Los Angeles, California); Mohammad Mahdi HASANI-SADRABADI (Los Angeles, California); Fatemeh S. MAJEDI (Los Angeles, California); Song LI (Beverly Hills, California) |
| ABSTRACT | A microparticle is described comprising an antigen and a costimulatory component derived from an antigen presenting cell. The microparticle may be used for stimulating T cells ex vivo, followed by administration to a subject, e.g., as part of a personalized, customized therapeutic treatment of cancer or a tumor, an autoimmune disease or an allergic reaction, hypersensitivity reaction, an infection or infectious disease, an injury or other damage, a transplant or other surgical site, or a blood clot. It may also be used for the controlled release of a cytokine for the regulation of immunity in general and for other therapeutic uses. Methods of treating a disease or medical condition in a subject by exposing leukocytes from the subject to the microparticle, then reinfusing the leukocytes into the subject are provided. Methods of preparing an activated cytotoxic T cell population specific for an antigen are also provided. |
| FILED | Friday, September 18, 2020 |
| APPL NO | 17/642515 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) A61K 9/1652 (20130101) A61K 9/1694 (20130101) A61K 31/727 (20130101) A61K 31/4439 (20130101) A61K 31/4709 (20130101) A61K 39/001 (20130101) A61K 39/0008 (20130101) A61K 39/0011 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 45/06 (20130101) A61K 47/02 (20130101) A61K 2039/5158 (20130101) A61K 2039/55516 (20130101) A61K 2039/55522 (20130101) A61K 2039/55527 (20130101) A61K 2039/55533 (20130101) A61K 2039/55538 (20130101) A61K 2039/55561 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/02 (20180101) A61P 31/00 (20180101) A61P 35/00 (20180101) A61P 37/04 (20180101) A61P 37/06 (20180101) A61P 37/08 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220331418 | Gale, JR. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
| INVENTOR(S) | Michael J. Gale, JR. (Seattle, Washington); Gretja Schnell (Seattle, Washington); Yueh-Ming Loo (Seattle, Washington) |
| ABSTRACT | Compositions and methods are provided that enable activation of innate immune responses through RIG-I like receptor signaling. The compositions and methods incorporate synthetic nucleic acid pathogen associated molecular patterns (PAMPs) that comprise elements initially characterized in, and derived from, the hepatitis C virus genome. |
| FILED | Monday, April 04, 2022 |
| APPL NO | 17/713149 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 39/12 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 45/06 (20130101) A61K 2039/555 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/117 (20130101) C12N 2770/24134 (20130101) C12N 2770/24234 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220331423 | Ertl et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hildegund C.J. Ertl (Villanova, Pennsylvania); Marcio O. LASARO (Maple Shade, New Jersey); Luis C.S. FERREIRA (Sao Paulo, Brazil) |
| ABSTRACT | Chimeric protein constructs including a herpesvirus glycoprotein D (gD) and a heterologous polypeptide that interact with herpes virus entry mediator (HVEM) and enhance and enhance an immune response against the heterologous polypeptide and methods for their use are provided. |
| FILED | Thursday, November 18, 2021 |
| APPL NO | 17/529665 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/245 (20130101) Original (OR) Class A61K 2039/53 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220331448 | VOGEL et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington State University (Pullman, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kara Rain VOGEL (Madison, Wisconsin); Kenneth Michael Gibson (Spokane, Washington); Garret Robert AINSLIE (Burlingame, California) |
| ABSTRACT | Provided herein are compositions and methods for treating succinic semialdehyde dehydrogenase deficiency (SSADHD). Compositions may include a gene encoding a functional succinic semialdehyde dehydrogenase (SSADH) enzyme, such as ALDH5A1, operably linked to a targeting vector. The functional SSADII enzyme is envisioned to lower the levels of circulating gamma-hydroxybutyric acid (GHB) and γ-aminobutyric acid (GABA). In some embodiments, combination therapies are envisioned, comprising administering to the subject therapeutically effective amounts of a combination of a composition comprising a gene encoding a functional SSADII enzyme operably linked to a targeting vector; one or more mTOR inhibitors; and a GABA-T inhibitor. Suitable mTOR inhibitors include rapamycin, while suitable GABA-T inhibitors include vigabatrin. |
| FILED | Wednesday, March 30, 2022 |
| APPL NO | 17/708799 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/18 (20130101) A61K 31/197 (20130101) A61K 31/436 (20130101) A61K 48/005 (20130101) Original (OR) Class A61K 48/0025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220331450 | Schaffer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David V. Schaffer (Danville, California); John G. Flannery (Berkeley, California); William A. Beltran (Philadelphia, Pennsylvania); Leah C. Byrne (San Francisco, California); Meike Visel (El Cerrito, California) |
| ABSTRACT | The present disclosure provides adeno-associated virus (AAV) virions with altered capsid protein, where the AAV virions exhibit greater infectivity of retinal cells compared to wild-type AAV. The present disclosure further provides methods of delivering a gene product to a retinal cell in an individual, and methods of treating ocular disease. |
| FILED | Thursday, June 16, 2022 |
| APPL NO | 17/842553 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 48/0075 (20130101) A61K 48/0091 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2750/14121 (20130101) C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) C12N 2750/14145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220331451 | Schaffer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David V. Schaffer (Danville, California); John G. Flannery (Berkeley, California); William A. Beltran (Philadelphia, Pennsylvania); Leah C. Byrne (San Francisco, California); Meike Visel (El Cerrito, California) |
| ABSTRACT | The present disclosure provides adeno-associated virus (AAV) virions with altered capsid protein, where the AAV virions exhibit greater infectivity of retinal cells compared to wild-type AAV. The present disclosure further provides methods of delivering a gene product to a retinal cell in an individual, and methods of treating ocular disease. |
| FILED | Thursday, June 16, 2022 |
| APPL NO | 17/842639 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 48/0075 (20130101) A61K 48/0091 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2750/14121 (20130101) C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) C12N 2750/14145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332683 | Wang |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jun Wang (Tucson, Arizona) |
| ABSTRACT | This invention is in the field of medicinal chemistry and relates to a new class of small-molecules having a pyrrolidinone-acetamide (or similar) structure (e.g., Formula I) which function as inhibitors of the SARS-CoV-2 papain-like protease (PLpro), which function as inhibitors of the SARS-CoV-2 related viral 3CL protease (MPpro), which function as therapeutics for the treatment of viral infection characterized with PLPpro and/or Mpro protease activity and/or expression (e.g., COVID-19), and which function as therapeutics for the treatment of other conditions characterized with PLPpro and/or Mpro protease activity and/or expression. |
| FILED | Tuesday, April 19, 2022 |
| APPL NO | 17/724125 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 31/16 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) A61P 31/14 (20180101) Heterocyclic Compounds C07D 207/46 (20130101) C07D 207/273 (20130101) Original (OR) Class C07D 209/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332695 | ZHANG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RTI INTERNATIONAL (Research Triangle Park, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yanan ZHANG (Research Triangle Park, North Carolina); Thuy T. NGUYEN (Research Triangle Park, North Carolina) |
| ABSTRACT | Heteroaryl and aliphatic analogs of diarylurea-based cannabinoid 1 receptor (CB1R) allosteric modulators are described. Exemplary analogs can provide improved potencies and pharmacokinetic properties. Methods of using the analogs to treat diseases mediated by CB1R, such as substance abuse and obesity, are described. |
| FILED | Thursday, June 25, 2020 |
| APPL NO | 17/621002 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/30 (20180101) Acyclic or Carbocyclic Compounds C07C 275/30 (20130101) Heterocyclic Compounds C07D 333/36 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332758 | OSMULSKI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The Universityof Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pawel A. OSMULSKI (San Antonio, Texas); Maria Gaczynska (San Antonio, Texas); Andrew Pickering (San Antonio, Texas); Przemyslaw Karpowicz (Gdansk, Poland); Elzbieta Jankowska (Gdansk, Poland) |
| ABSTRACT | Disclosed herein, are peptides capable of activating proteasome activity, and pharmaceutical compositions containing the peptides and methods treating Alzheimer's disease. Disclosed herein are compositions comprising: A) a peptide, wherein the peptide comprises the amino acid sequence GRKKR-RQ-AibG-RPS (SEQ ID NO: 4), or a fragment or variant thereof, B) a peptide, wherein the peptide comprises the amino acid sequence GRKKRRQ-AibG-QR-RKKRG (SEQ ID NO: 5), or a fragment or variant thereof, or C) a peptide, wherein the peptide comprises the amino acid sequence KKK/KKK-DABA-K KK (SEQ ID NO: 6) or a fragment or variant thereof. |
| FILED | Friday, September 11, 2020 |
| APPL NO | 17/642499 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Peptides C07K 5/0808 (20130101) C07K 7/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332772 | KALYANASUNDARAM |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ramaswamy KALYANASUNDARAM (Rockford, Illinois) |
| ABSTRACT | The present invention is a multivalent immunogenic composition for immunizing an animal against filariasis. In some embodiments, the antigens of the multivalent immunogenic composition are protein-based, DNA-based, or a combination thereof. This invention also provides a method and kit for detecting a filarial nematode and determining vaccine efficacy. |
| FILED | Monday, May 23, 2022 |
| APPL NO | 17/750968 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0003 (20130101) A61K 2039/53 (20130101) A61K 2039/70 (20130101) A61K 2039/545 (20130101) A61K 2039/55505 (20130101) Peptides C07K 14/4354 (20130101) Original (OR) Class C07K 2319/00 (20130101) C07K 2319/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0065 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) G01N 2333/4353 (20130101) G01N 2469/10 (20130101) G01N 2469/20 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332776 | WELLS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James A. WELLS (Oakland, California); Zachary B. HILL (Oakland, California); Alexander J. MARTINKO (Oakland, California) |
| ABSTRACT | The present invention provides antibody-based chemically induced dimerizers (AbCIDs) comprising an antibody domain that recognizes a chemical epitope created by the binding of an IMiD to a binding partner, such as cereblon, and methods to rapidly generate such AbCIDs. Several aspects described herein relate to systems, compositions, and methods including components of a chemically induced dimerizer (CID), such as an antibody chemically induced dimerizer (AbCID). |
| FILED | Thursday, August 06, 2020 |
| APPL NO | 17/633743 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/454 (20130101) A61K 31/711 (20130101) A61K 35/17 (20130101) A61K 38/465 (20130101) A61K 38/1709 (20130101) A61K 39/3955 (20130101) A61K 2039/5158 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/02 (20180101) Peptides C07K 14/4702 (20130101) Original (OR) Class C07K 16/44 (20130101) C07K 16/2803 (20130101) C07K 16/2809 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) C07K 2319/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332777 | Cooper et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vaughn Cooper (Wexford, Pennsylvania); Alfonso Santos López (Madrid, Spain) |
| ABSTRACT | Provided in this disclosure are methods of treating a bacterial infection comprising administering a formulation comprising an antimicrobial peptide described herein when administered to a subject. Further provided herein are methods of treating a bacterial infection wherein the bacterial infection comprises a bacterium with a mutation in a gene resulting in antibiotic resistance. |
| FILED | Wednesday, April 20, 2022 |
| APPL NO | 17/724927 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Peptides C07K 14/4723 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/12 (20130101) C12N 9/1007 (20130101) C12N 9/1048 (20130101) Enzymes C12Y 207/13003 (20130101) C12Y 301/01061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332785 | Deniger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Drew C. Deniger (Houston, Texas); Parisa Malekzadeh (Norfolk, Virginia); Steven A. Rosenberg (Potomac, Maryland); Anna Pasetto (Stockholm, Sweden) |
| ABSTRACT | Disclosed are isolated or purified T cell receptors (TCRs) having antigenic specificity for human p53R175H or human p53Y220C. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal. |
| FILED | Friday, June 26, 2020 |
| APPL NO | 17/620942 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/00 (20130101) Peptides C07K 14/7051 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5748 (20130101) G01N 2333/4748 (20130101) G01N 2333/7051 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332787 | Powell, Jr. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel J. Powell, Jr. (Bala Cynwyd, Pennsylvania) |
| ABSTRACT | The present invention relates to compositions and methods for treating HER2/Neu (ERBB2) expressing cancer cells. In some embodiments, the invention includes an isolated T cell receptor (TCR) having high affinity for and that specifically binds ERBB2369-377 epitope on a target cell. Other embodiments include a T cell or a population of T cells modified to express ERBB2-specific TCR. Further embodiments include methods of using ERBB2-specific TCR gene transfer for treating ERBB2 expressing cancer cells. Also included are methods and pharmaceutical compositions comprising the modified T cells for adoptive therapy. |
| FILED | Friday, April 29, 2022 |
| APPL NO | 17/733226 |
| CURRENT CPC | Peptides C07K 14/82 (20130101) C07K 14/4705 (20130101) C07K 14/7051 (20130101) Original (OR) Class C07K 16/28 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332798 | Nakai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Oregon Health and Science University (Portland, Oregon) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hiroyuki Nakai (West Linn, Oregon); Kei Adachi (Beaverton, Oregon); Helen Rappe Baggett (Hillsboro, Oregon) |
| ABSTRACT | The present disclosure relates to methods of producing monoclonal antibodies in animals. In particular, the disclosure provides a method of producing, in vivo, antibodies against viral capsids (VCs) derived from a non-enveloped virus (NEV). The method includes administering to a subject, by hydrodynamic-based transfection, a first set of genetic material encoding NEV structural proteins to induce the subject's intracellular translation and assembly of the proteins into viral capsids. The method also includes administering a second set of genetic material encoding NEV non-structural proteins to facilitate the intracellular assembly of the NEV structural proteins. Thus, this method may be used to produce subject-generated antibody-producing cells that secrete anti-VC antibodies that may be harvested and screened for monoclonal anti-VC antibodies. |
| FILED | Friday, October 02, 2020 |
| APPL NO | 17/765394 |
| CURRENT CPC | Peptides C07K 16/081 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332800 | DAS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Takeda Vaccines, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Takeda Vaccines, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Subash C. DAS (Billerica, Massachusetts); Isamu TSUJI (Cambridge, Massachusetts); Jill A. LIVENGOOD (Fort Collins, Colorado); Hansi DEAN (Weston, Massachusetts) |
| ABSTRACT | The present invention provides isolated monoclonal antibodies, or antigen-binding portions thereof, that bind to ZIKV glycoproteins, pharmaceutical compositions comprising the antibodies and methods of use. The antibodies, or antigen-binding portions thereof, according to the present invention are useful for inhibiting or neutralizing ZIKV activity, thus providing a means of treating or preventing ZIKV infection in humans. The antibodies, or antigen-binding portions thereof, according to the present invention may be used prophylactically or therapeutically and may be used alone or in combination with one or more other anti-viral agents or vaccines. |
| FILED | Friday, September 20, 2019 |
| APPL NO | 17/295770 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 45/06 (20130101) A61K 2039/545 (20130101) Peptides C07K 16/1081 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/31 (20130101) C07K 2317/92 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332805 | Finkelman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Cincinnati (Cincinnati, Ohio) |
| ASSIGNEE(S) | University of Cincinnati (Cincinnati, Ohio) |
| INVENTOR(S) | Fred Finkelman (Netanya, Israel); Unni Samavedam (Cincinnati, Ohio); Crystal Potter (Fairfield, Ohio); Ralf Ludwig (Gros Gronau, Germany); Anika Kasprick (Lubeck, Germany); Katja Bieber (Lubeck, Germany); Elizabeth Angerman (Cincinnati, Ohio) |
| ABSTRACT | Methods and compositions for treating a skin blistering disease are disclosed. In one embodiment, a method of treating a subject suffering from a skin blistering disease is disclosed. The method involves identifying an epithelial cell adhesion molecule associated with the skin blistering disease (EpCAM); then identifying a non-pathogenic monoclonal antibody (mAb) that targets the EpCAM; and then administering to the subject a therapeutically effective amount of the mAb. |
| FILED | Friday, September 11, 2020 |
| APPL NO | 17/641297 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/00 (20180101) Peptides C07K 16/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332813 | Strickland et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, Baltimore (Baltimore, Maryland); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dudley K. Strickland (Brookeville, Maryland); Joanna Cooper (Baltimore, Maryland); Selen M. Catania (Brookeville, Maryland); Mary M. Migliorini (Derwood, Maryland); Brian Hampton (Gaithersburg, Maryland); Bradley T. Hyman (Madison, New Hampshire); Aurelien Lathuiliere (Cambridge, Massachusetts) |
| ABSTRACT | The present invention provides methods and compositions for reducing internalization and/or trafficking of tau in neuronal cells comprising contacting the cells with an effective amount of an LRP1 and/or SorLA antagonist. The invention further provides a method of treating or preventing Alzheimer's disease in a subject in need thereof, comprising administering to the subject an effective amount of an LRP1 and/or SorLA antagonist. |
| FILED | Sunday, April 03, 2022 |
| APPL NO | 17/712167 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) A61P 35/00 (20180101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Peptides C07K 14/705 (20130101) C07K 16/28 (20130101) Original (OR) Class C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) C12N 2310/14 (20130101) C12N 2320/32 (20130101) C12N 2320/51 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332840 | Bhowmick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| ASSIGNEE(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| INVENTOR(S) | Neil Bhowmick (Beverly Hills, California); Bethany Smith (Los Angeles, California); Veronica Placencio (Valley Village, California); Anisha Madhav (Woodland, California) |
| ABSTRACT | Described herein is a method of sensitizing a cancer in a subject and methods of treating, slowing the progression of, reducing the severity of, preventing the recurrence of, and/or reducing the recurrence likelihood of a cancer in a subject. The invention further provides for a method of preventing the recurrence of and/or reducing the recurrence likelihood of a cancer in a subject who has been treated with a cancer therapy. |
| FILED | Wednesday, March 02, 2022 |
| APPL NO | 17/685040 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2896 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332843 | JOHNSTON et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen Albert JOHNSTON (Scottsdale, Arizona); Milene PETERSON (Scottsdale, Arizona) |
| ABSTRACT | A method of producing a therapeutic or preventive antibody for a cancer and/or tumor of interest is disclosed. The methods include binding antibodies of interest to frameshift peptide arrays, selecting frameshift peptides that are immunoreactive to the antibodies, and preparing an antibody composition against the selected frameshift peptides. Also disclosed are antibody compositions, methods of eliciting an immune response and methods of treatment using the methods of producing the antibodies as described herein. |
| FILED | Thursday, June 23, 2022 |
| APPL NO | 17/808402 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/30 (20130101) Original (OR) Class C07K 2317/10 (20130101) C07K 2317/73 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1037 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332869 | YANG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Rong YANG (Ithaca, New York); Trevor FRANKLIN (Ithaca, New York) |
| ABSTRACT | Provided are amphiphilic copolymers that include repeat units of formulas [Z]m and [P]n, wherein Z is a zwitterionic structural unit including at least one pendant heteroaromatic moiety, the heteroaromatic moiety containing a positively charged quaternary nitrogen atom (e.g., a pyridine ring), and wherein at least one negatively charged functional moiety is linked to the heteroaromatic moiety directly or through a linker, wherein the linker, where present, is an optionally substituted alkyl linker; P is a structural unit including a hydrophobic moiety, the hydrophobic moiety being a linear, branched, or cyclic fluorine-substituted C1-C20 moiety; m is an integer that is ≥1; and n is an integer that is ≥1. |
| FILED | Friday, November 12, 2021 |
| APPL NO | 17/454763 |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 212/36 (20130101) C08F 220/24 (20130101) C08F 226/06 (20130101) Original (OR) Class Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/1637 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332954 | LYNN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David LYNN (Middleton, Wisconsin); Harshit AGARWAL (Madison, Wisconsin) |
| ABSTRACT | The present invention provides liquid crystal (LC)-infused materials and methods for detecting compounds or impurities in liquid samples using such materials. These slippery materials comprise a lubricating liquid, preferably a thermotropic liquid crystal, and a solid substrate able to immobilize or host the lubricating liquid. The portion of the substrate coated by the lubricating fluid forms a slippery surface able to allow droplets of various materials to slide off the slippery surface in a manner dependent on the chemical composition of the droplet, which can be used to detect the presence of analytes, impurities and other molecules within the droplet. |
| FILED | Wednesday, April 06, 2022 |
| APPL NO | 17/714583 |
| CURRENT CPC | Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/00 (20130101) C09D 5/16 (20130101) Original (OR) Class Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition C10M 109/00 (20130101) Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions C10N 2050/08 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/02 (20130101) C12Q 1/18 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 19/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333050 | MILLER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Jordan MILLER (Houston, Texas); Ian KINSTLINGER (Solon, Ohio); Bagrat GRIGORYAN (Spring, Texas); Samantha PAULSEN (Newton, Massachusetts) |
| ABSTRACT | Some embodiments of the disclosure disclose a process for adhering cells, beads or particles to a surface of a material. The surface may be flat or curved and can be employed in the context of patterned or 3D printed hollow channels, facilitating the recapitulation of certain aspects of physiological systems. In various embodiments, interfacial cell seeding is accomplished by locally polymerizing a carrier containing a suspension of cells along the surface with a crosslinking molecule incorporated into the target material in advance of the interfacial polymerization. Polymerization of the carrier entraps the cells into controlled configuration along the surface. The techniques disclosed herein can be utilized for tissue engineering to build engineered organs/devices suitable for implanting into living organisms. |
| FILED | Friday, April 08, 2022 |
| APPL NO | 17/716389 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 31/145 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2533/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333053 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland); Pioneer Hi-Bred International, Inc. (Johnston, Iowa) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland); Pioneer Hi-Bred International, Inc. (Johnston, Iowa) |
| INVENTOR(S) | Tza-Huei Wang (Germantown, Maryland); Dong Jin Shin (Baltimore, Maryland); Fan-En Chen (Baltimore, Maryland); Yue Yun (Johnston, Iowa); Arturo M. Escajeda (Oakland, California); Ming X. Tan (San Ramon, California); Justin Schares (Ames, Iowa); Blake Freml (Urbandale, Iowa) |
| ABSTRACT | Embodiments of the invention relate to devices for assaying a biomolecule from a plant sample including: a microfluidic cartridge for assaying a biomolecule from a plant sample, including: a top layer; and a bottom layer spaced apart from the top layer in a generally parallel orientation with respect to the top layer, the bottom layer defining a plurality of wells therein that protrude from a surface of the bottom layer; and a filter module for filtering the plant sample, including a filter body defining: an upper portion including an inlet structure forming an inlet channel; and a bottom portion configured to accept and secure a filter membrane. The filter body is configured to accept a microvolume aliquot of the plant sample, the bottom structure includes an outlet structure forming an outlet channel on an outlet side of the filter membrane, and at least one of the plurality of wells includes an assay reagent solution. |
| FILED | Thursday, September 10, 2020 |
| APPL NO | 17/641071 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502 (20130101) B01L 2200/16 (20130101) B01L 2300/0681 (20130101) B01L 2400/043 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1017 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 35/0098 (20130101) G01N 2001/4088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333063 | Simko et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rachelle Simko (Pittsburgh, Pennsylvania); Adam Feinberg (Pittsburgh, Pennsylvania) |
| ABSTRACT | A method for micro-tissue encapsulation of cells includes coating a tissue scaffold stamp with an extracellular matrix compound; depositing the tissue scaffold stamp onto a thermoresponsive substrate; seeding the tissue scaffold stamp with a cell culture; incubating the cell culture on the tissue scaffold stamp at a temperature that is specified, wherein the cell culture forms a cell patch that is attached to the extracellular matrix compound; removing the thermoresponsive substrate by lowering the temperature; removing the tissue scaffold stamp from the cell patch to form a micro-tissue structure by dissolving the tissue scaffold stamp in a solvent; folding the micro-tissue structure by suspending the micro-tissue in the solvent to enable the cell patch to fold the micro-tissue structure; collecting the folded micro-tissue structure from the solvent; and administering the folded micro-tissue structure to an organism. |
| FILED | Wednesday, November 24, 2021 |
| APPL NO | 17/535094 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/16 (20130101) A61L 27/18 (20130101) A61L 27/38 (20130101) A61L 27/50 (20130101) A61L 27/3633 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0012 (20130101) C12N 5/0062 (20130101) Original (OR) Class C12N 5/0068 (20130101) C12N 2531/00 (20130101) C12N 2533/90 (20130101) C12N 2535/00 (20130101) C12N 2539/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333075 | Sentman |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Charles L. Sentman (Grantham, New Hampshire) |
| ABSTRACT | The invention is directed to modified T cells, methods of making and using isolated, modified T cells, and methods of using these isolated, modified T cells to address diseases and disorders. In one embodiment, this invention broadly relates to TCR-deficient T cells, isolated populations thereof, and compositions comprising the same. In another embodiment of the invention, these TCR-deficient T cells are designed to express a functional non-TCR receptor. The invention also pertains to methods of making said TCR-deficient T cells, and methods of reducing or ameliorating, or preventing or treating, diseases and disorders using said TCR-deficient T cells, populations thereof, or compositions comprising the same. |
| FILED | Tuesday, June 21, 2022 |
| APPL NO | 17/844982 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 39/0011 (20130101) A61K 2035/124 (20130101) A61K 2039/585 (20130101) A61K 2039/5156 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Original (OR) Class C12N 2501/515 (20130101) C12N 2511/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333107 | SEN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chandan K. SEN (Indianapolis, Indiana); Kanhaiya SINGH (Indianapolis, Indiana); Sashwati ROY (Indianapolis, Indiana); Mervin C. YODER (Indinaapolis, Indiana); Saba TABASUM (Indianapolis, Indiana); Ahmed Safwat ABOU-HASHEM (Indiaapolis, Indiana); Subhadip GHATAK (Indianapolis, Indiana) |
| ABSTRACT | Compositions and methods are provided for reprogramming dermal fibroblasts to exhibit vasculogenic properties including the ability to stimulate vasculogenesis in vivo. In accordance with one embodiment such compositions are used in conjunction with standard treatment for use on chronic wounds including in diabetic patients. |
| FILED | Friday, September 18, 2020 |
| APPL NO | 17/639263 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0656 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2320/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333115 | Harper et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (Columbus, Ohio); THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Scott Quenton Harper (Powell, Ohio); Wayne N. Frankel (Katonah, New York) |
| ABSTRACT | RNA interference-based methods and products for inhibiting the expression of pathogenic dynamin-1 variants are provided. Delivery vehicles such as recombinant adeno-associated viruses deliver DNAs encoding RNAs that inhibit the expression of the dynamin-1 variants. The methods treat, for example, developmental and epileptic encephalopathies. |
| FILED | Thursday, April 15, 2021 |
| APPL NO | 17/231963 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 15/1138 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333119 | Musunuru et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); The Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kiran Musunuru (Cambridge, Massachusetts); Chad A. Cowan (Cambridge, Massachusetts); Derrick J. Rossi (Newton, Massachusetts) |
| ABSTRACT | Disclosed herein are methods, compositions, and kits for high efficiency, site-specific genomic editing of cells. |
| FILED | Monday, April 25, 2022 |
| APPL NO | 17/728927 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0606 (20130101) C12N 15/63 (20130101) Original (OR) Class C12N 15/907 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333136 | Zolotukhin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated. (Gainesville, Florida) |
| INVENTOR(S) | Sergei Zolotukhin (Gainesville, Florida); David Tran (Gainesville, Florida); Oleksandr Kondratov (Gainesville, Florida) |
| ABSTRACT | Described herein are AAV particles having capsid proteins with amino acid substitutions that confer increased affinity for and transduction of glioma cells. The disclosed capsid proteins may be used in conjunction with any therapeutic transgene for treatment of cancer, including in the manufacture of an AAV particle. Also described are methods of identifying AAV variants having increased affinity for and transduction of specific tumor cell types. |
| FILED | Friday, August 07, 2020 |
| APPL NO | 17/633769 |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/861 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333138 | CHATTERJEE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | City of Hope (Duarte, California); Homology Medicines, Inc. (Bedford, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Saswati CHATTERJEE (Altadena, California); Laura Jane SMITH (Bedford, Massachusetts); Jeff Lynn ELLSWORTH (Lexington, Massachusetts); Hillard RUBIN (Northborough, Massachusetts); Jason Boke WRIGHT (Bedford, Massachusetts); James Anthony MCSWIGGEN (Arlington, Massachusetts) |
| ABSTRACT | Provided herein are adeno-associated virus (AAV) compositions that can restore F8 gene function in cell. Also provide are packaging systems for making the adeno-associated virus compositions. |
| FILED | Thursday, March 10, 2022 |
| APPL NO | 17/654300 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2710/10042 (20130101) C12N 2710/10043 (20130101) C12N 2710/10061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333158 | Seelig et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Georg Seelig (Seattle, Washington); Richard Muscat (London, United Kingdom); Alexander B. Rosenberg (Seattle, Washington) |
| ABSTRACT | Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens. |
| FILED | Tuesday, March 15, 2022 |
| APPL NO | 17/695671 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6855 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333164 | Gates et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kent Gates (Columbia, Missouri); Li-Qun Gu (Columbia, Missouri); Maryam Imani Nejad (Columbia, Missouri); Xu Guo (Columbia, Missouri) |
| ABSTRACT | Provided herein are probes in which an Ap site of a probe strand can selectively cross-link with a 2′-deoxyguanosine (dG) of a target strand. Also provided for are methods of using such probes to generate and detect crosslinked molecules and methods of detecting disease associated genetic mutations. |
| FILED | Monday, August 10, 2020 |
| APPL NO | 17/633746 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) Original (OR) Class C12Q 1/6876 (20130101) C12Q 2600/112 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333169 | LANFEAR |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Henry Ford Health System (Detroit, Michigan) |
| ASSIGNEE(S) | Henry Ford Health System (Detroit, Michigan) |
| INVENTOR(S) | David Ethan LANFEAR (Birmingham, Michigan) |
| ABSTRACT | The present disclosure provides methods for creation, validation and application of a polygenic response predictor (PRP) score which can identify and/or predict beta-blocker survival benefit in heart failure. In one aspect, provided herein are systems and methods for identifying, diagnosing, and treating heart failure patients of European descent who are likely to respond to beta-blocker treatment. |
| FILED | Sunday, September 13, 2020 |
| APPL NO | 17/642577 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/138 (20130101) A61K 31/165 (20130101) A61K 31/166 (20130101) A61K 31/404 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/04 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6827 (20130101) Original (OR) Class C12Q 1/6858 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333172 | Cheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Jackson Laboratory (Bar Harbor, Maine) |
| ASSIGNEE(S) | The Jackson Laboratory (Bar Harbor, Maine) |
| INVENTOR(S) | Albert Cheng (Bar Harbor, Maine); Patricia Clow (Bar Harbor, Maine) |
| ABSTRACT | Provided herein are methods of imaging non-repetitive genomic loci using unique guide ribonucleic acids (gRNAs), an RNA-guided nuclease, and a detectable conjugate. |
| FILED | Thursday, August 13, 2020 |
| APPL NO | 17/635424 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) C12Q 1/6841 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333208 | Gootenberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Jonathan Gootenberg (Cambridge, Massachusetts); Omar Abudayyeh (Cambridge, Massachusetts); Jeremy Koob (Cambridge, Massachusetts); Rahul Vedula (Boston, Massachusetts); Coleman Lindsley (Boston, Massachusetts); Feng Zhang (Cambridge, Massachusetts) |
| ABSTRACT | Systems and methods for rapid diagnostics related to the use of CRISPR effector systems and optimized guide sequences, including multiplex lateral flow diagnostic devices and methods of use, including for detection of cancer markers, are provided. |
| FILED | Thursday, September 03, 2020 |
| APPL NO | 17/640016 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/682 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220334034 | WOOLLEY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Adam T. WOOLLEY (Orem, Utah); Anna V. BICKHAM (Provo, Utah); Gregory P. NORDIN (Lindon, Utah) |
| ASSIGNEE(S) | Brigham Young University (Provo, Utah) |
| INVENTOR(S) | Adam T. WOOLLEY (Orem, Utah); Anna V. BICKHAM (Provo, Utah); Gregory P. NORDIN (Lindon, Utah) |
| ABSTRACT | Miniaturized solid-phase extraction (SPE) systems and processes are disclosed. The systems and methods enable preconcentration methods for sample preparation that can be performed on a variety of specimens. The miniaturization of SPE system is accomplished with 3D-printed microfluidic device for fast and simple extraction of analytes. |
| FILED | Thursday, April 07, 2022 |
| APPL NO | 17/658442 |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/405 (20130101) Original (OR) Class G01N 33/582 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220334097 | Wanunu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Meni Wanunu (Sharon, Massachusetts); Mohammadamin Alibakhshi (Boston, Massachusetts); Fatemeh Farhangdoust (Allston, Massachusetts) |
| ABSTRACT | A system and apparatus are provided for sensing a molecule in a sample for identifying the molecule in the sample. Also provided is a method of manufacturing an apparatus for sensing a molecule in a sample. The system and apparatus may contain a composition of a mixture of a buffer solution and a sample solution containing a sample. The apparatus contains a series of wells. The sample is deposited into the system and a molecule having an electric charge in the sample attaches to a layer in a well of the apparatus, allowing for a sensor connected to the apparatus to identify the molecule. |
| FILED | Friday, September 25, 2020 |
| APPL NO | 17/754114 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6452 (20130101) G01N 33/48721 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220334110 | Puleo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Global Life Sciences Solutions USA LLC (Marlborough, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher Michael Puleo (Niskayuna, New York); Ernest William Kovacs (Cohoes, New York); Brian Michael Davis (Niskayuna, New York) |
| ABSTRACT | Described are multi-functional beads and methods to capture rare cells directly from low-volume biological samples and perform both functional and genomic assays from those cells. This is accomplished using a multifunctional capture bead that allows co-localization of both the single cell capture element and the molecular assay components. When combined with a digital microfluidic platform this enables encoding and/or barcoding of specific single cells. |
| FILED | Thursday, June 30, 2022 |
| APPL NO | 17/855000 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/00 (20130101) B01L 3/50273 (20130101) B01L 3/502753 (20130101) B01L 2200/141 (20130101) B01L 2200/0668 (20130101) B01L 2300/0829 (20130101) B01L 2300/0851 (20130101) B01L 2400/043 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/505 (20130101) G01N 33/54326 (20130101) Original (OR) Class G01N 33/54346 (20130101) G01N 33/56972 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220334115 | McDevitt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John T. McDevitt (New York, New York); Michael P. McRae (Houston, Texas) |
| ABSTRACT | The present disclosure is related to systems and methods to be used as aids in the diagnosis of risk for carcinoma, lesions, or dysplasia by identifying cellular phenotype characteristics of cell samples, including percentage of mature squamous cells, presence or absence of nuclear actin in mature squamous cells, percentage of non-mature squamous cells, percentage of small round cells, percentage of white blood cells, and percentage of lone nuclei. |
| FILED | Wednesday, May 04, 2022 |
| APPL NO | 17/736535 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6875 (20130101) G01N 33/57407 (20130101) Original (OR) Class G01N 33/57492 (20130101) G01N 33/57496 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/40 (20180101) G16H 10/60 (20180101) G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220334119 | RODLAND et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington); THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (BETHESDA, Maryland); THE UNITED STATES OF AMERICA,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Karin RODLAND (Richland, Washington); Tao LIU (Richland, Washington); Jennifer CULLEN (Bethesda, Maryland); Gyorgy PETROVICS (Bethesda, Maryland); Jacob KAGAN (Bethesda, Maryland); Sudhir SRIVASTAVA (Bethesda, Maryland) |
| ABSTRACT | Disclosed herein are methods of diagnosing or prognosing aggressive prostate cancer in a subject and methods of treating a subject with aggressive prostate cancer. For example, the methods can include measuring increased expression of aggressive prostate cancer-related molecules (such as FOLH1, SPARC, TGFB1, CAMKK2, NCOA2, EGFR, or PSA) and optionally administering a therapeutically effective amount of aggressive prostate cancer therapy. |
| FILED | Wednesday, August 19, 2020 |
| APPL NO | 17/634626 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6848 (20130101) G01N 33/57434 (20130101) Original (OR) Class G01N 2333/495 (20130101) G01N 2333/948 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220334121 | Chaudhuri et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Washington University (St. Louis, Missouri); NATIONAL INSTITUTES OF HEALTH (BETHESDA, Maryland) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri); NATIONAL INSTITUTES OF HEALTH (BETHESDA, Maryland) |
| INVENTOR(S) | Aadel Chaudhuri (St. Louis, Missouri); Paul Jones (St. Louis, Missouri); Jeffrey Szymanski (St. Louis, Missouri); Angela Hirbe (St. Louis, Missouri); Russell Sundby (Baltimore, Maryland); John Shern (Bethesda, Maryland) |
| ABSTRACT | Among the various aspects of the present disclosure is the provision of methods for detecting cancer in Neurofibromatosis Type 1 (NF1) patients. |
| FILED | Thursday, January 27, 2022 |
| APPL NO | 17/586676 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57488 (20130101) Original (OR) Class Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 30/20 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220334131 | Schwartz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ELEVEN P15 INC. (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David A. Schwartz (Denver, Colorado); Ivana V. Yang (Denver, Colorado); Susan k. Mathal (Dallas, Texas) |
| ABSTRACT | Disclosed herein are biomarkers related to preclinical pulmonary fibrosis and methods of identifying the same. In embodiments, the biomarkers are proteins. In embodiments, the biomarkers are transcripts. |
| FILED | Monday, May 18, 2020 |
| APPL NO | 17/600876 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/496 (20130101) A61K 31/4418 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) Original (OR) Class G01N 2800/12 (20130101) G01N 2800/7052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220334132 | SCHWADERER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana); THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (Columbus, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew L. SCHWADERER (Zionsville, Indiana); Dong LIANG (Indianapolis, Indiana); David HAINS (Indianapolis, Indiana); Joshua R. WATSON (Columbus, Indiana) |
| ABSTRACT | Compositions and methods are provided for the detection of a urinary tract infection by detecting and quantitating at least eight proteins in the sample. Aptamer based proteomic analysis revealed a urine protein signature that differentiated urinary tract infections from culture negative urine samples, regardless of pyuria status. Inclusion of these candidate biomarkers, either alone or in combination, to traditional urinalysis biomarkers assist clinicians in identifying true urinary tract infections, from culture negative pyuria, at the point of care The identified patients can then be treated with a therapeutic pharmaceutical composition comprising standard antibiotics. |
| FILED | Thursday, August 06, 2020 |
| APPL NO | 17/631899 |
| CURRENT CPC | Peptides C07K 16/24 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) Original (OR) Class G01N 2800/348 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220334206 | Viessmann et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Olivia M. Viessmann (Cambridge, Massachusetts); Jonathan R. Polimeni (Cambridge, Massachusetts); Bruce Fischl (Cambridge, Massachusetts) |
| ABSTRACT | Anatomical, physiological, instrumental, and other related biases are removed from functional magnetic resonance imaging (“fMRI”) signal data using deep learning algorithms and/or models, such as a neural network. Bias characterization data are used as an auxiliary input to the neural network. The bias characterization data can be subject-specific bias characterization data (e.g., cortical thickness maps, cortical orientation angle maps, vasculature maps), hardware-specific bias characterization data (e.g., coil sensitivity maps, coil transmission profiles), or both. The subject-specific bias characterization data can be extracted from the fMRI signal data using a second neural network. The bias-reduced fMRI signal data can include time-series signals, functional activation maps, functional connectivity maps, or combinations thereof. |
| FILED | Monday, April 18, 2022 |
| APPL NO | 17/659599 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4806 (20130101) Original (OR) Class G01R 33/5608 (20130101) Computer Systems Based on Specific Computational Models G06N 3/0454 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220334207 | Fu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhiyang Fu (Tucson, Arizona); Maria I. Altbach (Tucson, Arizona); Ali Bilgin (Tucson, Arizona) |
| ABSTRACT | A method for producing a streak-suppressed MR image of a subject includes (i) generating an interference correlation matrix from M coil images, (ii) producing eigenvectors of the interference correlation matrix, and (iii) determining, from the subspace-eigenvectors, a projection matrix of the interference null space. The subspace-eigenvectors include a plurality of subspace-eigenvectors that span an interference subspace and a plurality of null-space-eigenvectors that span an interference null space. The method also includes generating, from N coil images derived from a respective one of N MR signals, N streak-suppressed multi-coil images by either (i) preprocessing the N coil images with the projection matrix and applying an image-reconstruction technique to each of the resultant N preprocessed coil images, or (ii) applying an image-reconstruction technique to each of the N coil images to obtain N reconstructed coil images and post-processing the resultant N reconstructed coil images with the projection matrix. |
| FILED | Tuesday, April 19, 2022 |
| APPL NO | 17/659712 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5608 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 11/005 (20130101) G06T 11/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220334208 | TAMIR et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Subtle Medical, Inc. (Menlo Park, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan TAMIR (Menlo Park, California); Srivathsa PASUMARTHI VENKATA (Menlo Park, California); Tao ZHANG (Menlo Park, California); Enhao GONG (Menlo Park, California) |
| ABSTRACT | Methods and systems are provided for improving model robustness and generalizability. The method may comprise: acquiring, using a medical imaging apparatus, a medical image of a subject; reformatting the medical image of the subject in multiple scanning orientations; applying a deep network model to the medical image to improve the quality of the medical image; and outputting an improved quality image of the subject for analysis by a physician. |
| FILED | Wednesday, March 23, 2022 |
| APPL NO | 17/702468 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5601 (20130101) G01R 33/5608 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 3/60 (20130101) G06T 5/50 (20130101) G06T 2207/10088 (20130101) G06T 2207/20084 (20130101) G06T 2207/20216 (20130101) G06T 2207/30004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220334808 | Mostafa et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Javed Mostafa (Cary, North Carolina); Xiaopeng Lu (Pittsburgh, Pennsylvania); Sandeep Avula (Carrboro, North Carolina) |
| ABSTRACT | How to correctly understand natural language query and catch the useful information from it is a long-standing research question in the chatbot field. However, in many cases only a small set of words are sufficient for closed-domain tasks. In this paper, we propose Minimal Dictionary Language (MDL): a simple language architecture which allows users to express their needs through certain basic syntax. For the pilot study, we selected Enron email open dataset[2] for our experimental use and apply MDL as the language for email retrieval task. We also built a front-end search interface by Python Flask and Vue.js for test and evaluation purposes. |
| FILED | Friday, December 18, 2020 |
| APPL NO | 17/633184 |
| CURRENT CPC | Electric Digital Data Processing G06F 8/33 (20130101) Original (OR) Class G06F 40/205 (20200101) G06F 40/242 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220337333 | Bernstein et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Liane Sarah Beland Bernstein (Cambridge, Massachusetts); Alexander Sludds (Cambridge, Massachusetts); Dirk Robert ENGLUND (Brookline, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Liane Sarah Beland Bernstein (Cambridge, Massachusetts); Alexander Sludds (Cambridge, Massachusetts); Dirk Robert ENGLUND (Brookline, Massachusetts) |
| ABSTRACT | Deep neural networks (DNNs) have become very popular in many areas, especially classification and prediction. However, as the number of neurons in the DNN increases to solve more complex problems, the DNN becomes limited by the latency and power consumption of existing hardware. A scalable, ultra-low latency photonic tensor processor can compute DNN layer outputs in a single shot. The processor includes free-space optics that perform passive optical copying and distribution of an input vector and integrated optoelectronics that implement passive weighting and the nonlinearity. An example of this processor classified the MNIST handwritten digit dataset (with an accuracy of 94%, which is close to the 96% ground truth accuracy). The processor can be scaled to perform near-exascale computing before hitting its fundamental throughput limit, which is set by the maximum optical bandwidth before significant loss of classification accuracy (determined experimentally). |
| FILED | Wednesday, February 16, 2022 |
| APPL NO | 17/673268 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/0675 (20130101) Transmission H04B 10/541 (20130101) H04B 10/614 (20130101) Multiplex Communication H04J 14/0224 (20130101) H04J 14/0234 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220337963 | Nakajima et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts); Universität Basel (Petersgraben, Switzerland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hideko Heidi Nakajima (Andover, Massachusetts); Christof Theodor Stieger (Liebefeld, Switzerland); Darcy Lynn Frear (Cambridge, Massachusetts); Hannes Maier (Hannover, Germany) |
| ABSTRACT | To account for the anatomical variability of the round window, and its surrounding bony structure, and ensure the safety of the delicate round window membrane (RWM) and structures in the cochlea closely adjacent to the RWM, the disclosure provides devices and methods that safely and effectively couple the motion of a variety of actuators to the RWM. |
| FILED | Friday, June 24, 2022 |
| APPL NO | 17/849272 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36038 (20170801) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 25/60 (20130101) H04R 25/606 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20220330533 | SMANSKI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Joseph SMANSKI (Falcon Heights, Minnesota); Siba DAS (Falcon Heights, Minnesota); Maciej MASELKO (Sydney, Australia) |
| ABSTRACT | A system for batch production of the heterogametic sex of a biological species generally includes a first strain of a biological species genetically engineered to include a conditional Y-linked (or Z-linked) genetic lethal circuit and a second strain of the biological species genetically engineered to include a conditional X-linked (or W-linked) genetic lethal circuit. |
| FILED | Thursday, October 01, 2020 |
| APPL NO | 17/763849 |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0339 (20130101) Original (OR) Class A01K 2217/05 (20130101) A01K 2217/203 (20130101) A01K 2227/706 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8509 (20130101) C12N 2800/90 (20130101) C12N 2800/105 (20130101) C12N 2830/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220330843 | Saini et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Teliatry, Inc. (Richardson, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rahul Saini (Allen, Texas); Dane William Grasse (Santa Clara, California); Vishnoukumaar Sivaji (Richardson, Texas) |
| ABSTRACT | In one embodiment, a sensor includes a capsule having a cavity and a sheath, a transducer coupled to electronic circuitry in the cavity, and a clip outside the capsule. The capsule and the clip are configured to hold in vivo an object within an opening between the capsule and the clip. The transducer is configured to detect an incoming signal indicative of a physiological parameter of the object being held, and the electronic circuitry is configured to wirelessly transmit a signal containing information about the physiological parameter obtained from the incoming signal. The sensor is part of a measurement system to measure the physiological parameter. Another embodiment describes a method using the measurement system. |
| FILED | Monday, April 19, 2021 |
| APPL NO | 17/233776 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0031 (20130101) A61B 5/076 (20130101) A61B 5/0538 (20130101) A61B 5/1473 (20130101) A61B 5/02158 (20130101) Original (OR) Class A61B 5/6861 (20130101) A61B 5/6898 (20130101) A61B 5/14539 (20130101) A61B 6/425 (20130101) A61B 8/12 (20130101) A61B 2560/0214 (20130101) A61B 2562/164 (20130101) A61B 2562/0233 (20130101) A61B 2562/0247 (20130101) A61B 2562/0261 (20130101) A61B 2562/0271 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/20 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220331185 | Mooney et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dephy, Inc. (Maynard, Massachusetts) |
| ASSIGNEE(S) | Dephy, Inc. (Maynard, Massachusetts) |
| INVENTOR(S) | Luke Mooney (Sudbury, Massachusetts); Jean-Francois Duval (Belmont, Massachusetts); William Marvin (Canton, Massachusetts) |
| ABSTRACT | The present invention is directed to the affixion of an exoskeleton device that can include multiple rotational degrees of freedom in its attachment mechanism to approximate linear motion orthogonal to the person's line of action. The present invention can include one or more additional, non-parallel degrees of freedom. The present invention provides a sliding mechanism for adjusting the exoskeleton mating point along the user's body. |
| FILED | Tuesday, June 28, 2022 |
| APPL NO | 17/851807 |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/0237 (20130101) Original (OR) Class A61H 3/00 (20130101) A61H 2003/007 (20130101) A61H 2201/165 (20130101) A61H 2205/106 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0006 (20130101) Capstans; Winches; Tackles, e.g Pulley Blocks; Hoists B66D 1/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220331490 | Lu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Helen H. Lu (New York, New York); Christopher Z. Mosher (New York, New York); Romare Antrobus (New York, New York); James C. Hone (New York, New York); Theanne Schiros (New York, New York); Yilin Yang (New York, New York) |
| ABSTRACT | A fibrous polymeric scaffold for soft tissue engineering comprises electrospun fibers including a polymeric blend and graphite particles embedded therein. |
| FILED | Wednesday, February 09, 2022 |
| APPL NO | 17/668332 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/443 (20130101) Original (OR) Class A61L 2430/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220331583 | Ludwig et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumi Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kip Ludwig (Middleton, Wisconsin); Justin Williams (Cambridge, Wisconsin); Angela Williams (Cambridge, Wisconsin); Samuel Poore (Madison, Wisconsin) |
| ABSTRACT | Electrical stimulation of specific facial and lingual nerves creates a more sustained pulsatility activity compared to stimulation of other cranial nerves. Pulsatility of arteries has intrinsic time constraints related to the time for vasodilation/constriction and time to return to baseline (TBL) after electrical stimulation which may affect the pulsatility response. Control of temporal patterning and the stimulation waveform maximizes the physiological response to cerebral pulsatility and its resulting effects on cerebral spinal fluid penetration into the brain parenchyma for a multitude of therapeutic uses including clearing misfolded proteins and/or administered pharmacological agents, diluting endogenous neurochemical concentrations within the brain, and reducing non-synaptic coupling. |
| FILED | Thursday, June 30, 2022 |
| APPL NO | 17/854078 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0432 (20130101) A61N 1/0548 (20130101) Original (OR) Class A61N 1/36025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332409 | COX et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LOCKHEED MARTIN CORPORATION (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John C. COX (Jupiter, Florida); Steven P. LOZANO (Stratford, Connecticut); David H. HUNTER (Stratford, Connecticut); Emmett Emile MENAIR (Stratford, Connecticut); Jacob Adam FEHRMAN (Stratford, Connecticut); John Devin CARROLL (Fortworth, Texas) |
| ABSTRACT | A tunable mass damper assembly is attachable to a rotor blade. The tunable mass damper assembly comprises a base configured to be attached to the rotor blade and a pendulum mass structure movably attached to the base and configured to move relative to the base in accordance with a rotational speed of the rotor blade about a rotor axis. The pendulum mass structure is configured to reduce vibratory forces of the rotor blade induced by a rotation of the rotor blade about the rotor axis. An entirety of the pendulum mass structure being configured to be contained within and enclosed by the rotor blade. |
| FILED | Friday, April 16, 2021 |
| APPL NO | 17/233360 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/001 (20130101) Original (OR) Class B64C 27/10 (20130101) B64C 27/473 (20130101) B64C 2027/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332576 | Becker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Carol A. Becker (Del Mar, California); Wayne E. Glad (Del Mar, California) |
| ABSTRACT | An apparatus and method generate oxygen gas from sodium percarbonate and water including seawater. The apparatus includes a chamber, a valve system, and an output port. The valve system controls combining a quantity of the sodium percarbonate, a quantity of the water, a quantity of potassium iodide, and optionally a quantity of sodium sulfate decahydrate. A chemical reaction between the sodium percarbonate and the water in the chamber generates oxygen gas, which is output at an output port from the chamber. The potassium iodide is a catalyst for the chemical reaction and optionally the sodium sulfate decahydrate is a temperature moderator for the chemical reaction. A ratio between the water and the sodium percarbonate is in a range of 2.5 to 8 by weight. A ratio of the potassium iodide per liter of the water yields a molarity in a range of 0.25 to 1.25. |
| FILED | Friday, April 16, 2021 |
| APPL NO | 17/232741 |
| CURRENT CPC | Devices, Apparatus or Methods for Life-saving A62B 7/08 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 8/0278 (20130101) B01J 2208/00752 (20130101) Non-metallic Elements; Compounds Thereof; C01B 13/0207 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/0618 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332632 | Mathewson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Carly Jean Mathewson (University Park, Pennsylvania); John Christopher Mauro (University Park, Pennsylvania); Venkatraman Gopalan (University Park, Pennsylvania); John Victor Badding (University Park, Pennsylvania) |
| ABSTRACT | Disclosed herein are glass compositions, articles made from the disclosed glass compositions, and methods of making the same. More specifically, disclosed herein is a glass composition comprising from about 10 to about 14 mol % of K2O; from 0 to about 4 mol % of CaO; from about 14 to about 18 mol % of Al2O3; and from about 66 to about 74 mol % SiO2. |
| FILED | Monday, December 13, 2021 |
| APPL NO | 17/549213 |
| CURRENT CPC | Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 3/083 (20130101) C03C 3/087 (20130101) C03C 4/0071 (20130101) C03C 13/046 (20130101) Original (OR) Class C03C 2204/00 (20130101) C03C 2213/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332670 | ZHOU et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Xuhao ZHOU (Evanston, Illinois); Zhao WANG (Evanston, Illinois); Naneki C. McCALLUM (Evanston, Illinois); Nathan C. GIANNESCHI (Evanston, Illinois); Zofia E. SIWICKA (Evanston, Illinois) |
| ABSTRACT | In an aspect, a plurality of artificial melanin nanoparticles are provided, wherein: each melanin nanoparticle of the plurality of artificial melanin nanoparticles comprises a plurality of melanin oligomers; each melanin oligomer comprises a plurality of covalently-bonded melanin base units; and each melanin base unit comprises substituted or unsubstituted naphthalene. In an aspect, porous artificial melanin materials and methods of synthesizing porous artificial melanin materials are provided. |
| FILED | Friday, June 26, 2020 |
| APPL NO | 17/621908 |
| CURRENT CPC | Preparation or Pretreatment of the Material to be Shaped; Making Granules or Preforms; Recovery of Plastics or Other Constituents of Waste Material Containing Plastics B29B 9/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Acyclic or Carbocyclic Compounds C07C 29/76 (20130101) C07C 33/26 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/44 (20130101) C08G 2261/362 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332773 | LAWRENCE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Silk Technologies, Ltd. (Plymouth, Minnesota) |
| ASSIGNEE(S) | Silk Technologies, Ltd. (Plymouth, Minnesota) |
| INVENTOR(S) | Brian D. LAWRENCE (Plymouth, Minnesota); David W. INFANGER (Plymouth, Minnesota) |
| ABSTRACT | Described herein are methods for reducing inflammation by administration of an effective amount of silk-derived proteins (SDP) or a fraction thereof to a subject having an inflammatory condition. The methods include the treatment of inflammatory conditions and wounds, including corneal wounds, comprising the topical administration of an effective amount of SDP material as described herein. |
| FILED | Monday, February 07, 2022 |
| APPL NO | 17/666268 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/14 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 38/00 (20130101) A61K 38/012 (20130101) A61K 47/02 (20130101) A61K 47/10 (20130101) A61K 47/26 (20130101) A61K 47/34 (20130101) A61K 47/38 (20130101) A61K 47/42 (20130101) A61K 47/183 (20130101) Peptides C07K 14/43586 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332869 | YANG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Rong YANG (Ithaca, New York); Trevor FRANKLIN (Ithaca, New York) |
| ABSTRACT | Provided are amphiphilic copolymers that include repeat units of formulas [Z]m and [P]n, wherein Z is a zwitterionic structural unit including at least one pendant heteroaromatic moiety, the heteroaromatic moiety containing a positively charged quaternary nitrogen atom (e.g., a pyridine ring), and wherein at least one negatively charged functional moiety is linked to the heteroaromatic moiety directly or through a linker, wherein the linker, where present, is an optionally substituted alkyl linker; P is a structural unit including a hydrophobic moiety, the hydrophobic moiety being a linear, branched, or cyclic fluorine-substituted C1-C20 moiety; m is an integer that is ≥1; and n is an integer that is ≥1. |
| FILED | Friday, November 12, 2021 |
| APPL NO | 17/454763 |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 212/36 (20130101) C08F 220/24 (20130101) C08F 226/06 (20130101) Original (OR) Class Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/1637 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332918 | Boyd et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Darryl A. Boyd (Fort Washington, Maryland); Vinh Q. Nguyen (Fairfax, Virginia); Nia A. Pollard (Alexandria, Virginia); Frederic H. Kung (Alexandria, Virginia); Daniel J. Gibson (Cheverly, Maryland); Jason D. Myers (Alexandria, Virginia); Colin C. Baker (Alexandria, Virginia); Woohong Kim (Lorton, Virginia); Jasbinder S. Sanghera (Ashburn, Virginia) |
| ABSTRACT | A polymer comprising one or more chalcogenide elements and one or more crosslinking moieties. The crosslinking moieties may be organic, inorganic, or both. Also disclosed is the related method for making a polymer comprising purifying a chalcogenide polymer powder comprising one or more chalcogenide elements, melting the purified chalcogenide polymer powder, adding one or more crosslinking moieties to the melted chalcogenide polymer, and curing the modified chalcogenide polymer at a temperature between 150 and 200° C. |
| FILED | Thursday, June 30, 2022 |
| APPL NO | 17/855021 |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 12/36 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/24 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332975 | Benkoski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jason J. Benkoski (Catonsville, Maryland); Rengaswamy Srinivasan (Ellicott City, Maryland); Christopher M. Hoffman, JR. (Odenton, Maryland); Keith S. Caruso (Catonsville, Maryland) |
| ABSTRACT | Coating compositions include a binder that has a first polymeric material that does not undergo ultraviolet (UV) degradation and/or does not absorb UV radiation/light. The coating compositions may further include at least a first UV-reflective pigment dispersed throughout the binder. The coating compositions may be provided in a cured form as a solid coating layer that may overly at least a portion of a substrate. |
| FILED | Wednesday, May 18, 2022 |
| APPL NO | 17/747286 |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 2003/2296 (20130101) C08K 2201/003 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 183/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333166 | Connolly et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Integrated Nano-Technologies, Inc. (Henrietta, New York) |
| ASSIGNEE(S) | Integrated Nano-Technologies, Inc. (Henrietta, New York) |
| INVENTOR(S) | Dennis M. Connolly (Rochester, New York); Tara Holz (Henrietta, New York); Vera Tannous (Penfield, New York); Christopher Kilcoin (Boulder Creek, California); Konstantin Aptekarev (Santa Cruz, California); David B. Bailey (Webster, New York); Richard S. Murante (Henrietta, New York); Nathaniel E. Wescott (West Henrietta, New York) |
| ABSTRACT | A method for preparing a sample by utilizing a shearing force in the presence of a size stabilizer to break apart the sample to obtain nucleic acid molecules in a usable size range. Once nucleic acid molecules are obtained, magnetic nanoparticles are used to concentrate and clean the nucleic acid molecules for further testing. |
| FILED | Monday, January 31, 2022 |
| APPL NO | 17/589250 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502 (20130101) B01L 2200/0631 (20130101) B01L 2300/0681 (20130101) Apparatus for Enzymology or Microbiology; C12M 47/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/066 (20130101) C12N 15/10 (20130101) C12N 15/1013 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/02 (20130101) C12Q 1/6806 (20130101) C12Q 1/6825 (20130101) Original (OR) Class C12Q 2531/113 (20130101) C12Q 2563/107 (20130101) C12Q 2563/143 (20130101) C12Q 2565/629 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/286 (20130101) G01N 2001/2866 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333216 | HECHT et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona); EMORY UNIVERSITY (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sidney HECHT (Phoenix, Arizona); Jesse WAGGONER (Atlanta, Georgia); Mingxuan GAO (Chongqing, China PRC); Shengxi CHEN (Chandler, Arizona) |
| ABSTRACT | Described herein are systems and methods that may be used to differentially detect viral serotype specific nucleic acid. For example, these systems may comprise multiple DNA-nanostructures, capture oligonucleotides and protector oligonucleotides, wherein each DNA-nanostructure and its associated capture oligonucleotide and protector oligonucleotide are specific for a unique viral type or serotype. |
| FILED | Wednesday, June 03, 2020 |
| APPL NO | 17/616341 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/701 (20130101) Original (OR) Class C12Q 1/6818 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333266 | Shalaev et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana); Palacky University (Olomouc, Czech Republic); University of Erlangen-Nuremberg (Erlangen, Germany) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vladimir M. Shalaev (West Lafayette, Indiana); Zhaxylyk Kudyshev (West Lafayette, Indiana); Alexandra Boltasseva (West Lafayette, Indiana); Alberto Naldoni (Olomouc, Czech Republic); Alexander Kildishev (West Lafayette, Indiana); Luca Mascaretti (Olomouc, Czech Republic); Stêphán Kment (Olomouc, Czech Republic); Radek Zboril (Olomouc, Czech Republic); Jeong Eun Yoo (Erlangen, Germany); Patrik Schmuki (Erlangen, Germany) |
| ABSTRACT | A thermoplasmonic device includes a titanium film and a plurality of titanium nitride tube elements disposed on the titanium film. Each of the titanium nitride tube elements includes an open top and a titanium nitride bottom. Each of the titanium nitride tube elements has titanium nitride tubular middle portion that extends from the open top to the titanium nitride bottom. |
| FILED | Monday, May 02, 2022 |
| APPL NO | 17/734934 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 21/076 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 11/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333274 | Skinner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jack L. Skinner (Butte, Montana); Isaac C. Gilfeather (Butte, Montana); Harold W. Pearson-Nadal (Butte, Montana); Jessica M. Andriolo (Butte, Montana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jack L. Skinner (Butte, Montana); Isaac C. Gilfeather (Butte, Montana); Harold W. Pearson-Nadal (Butte, Montana); Jessica M. Andriolo (Butte, Montana) |
| ABSTRACT | Applications of electrospinning (ES) range from fabrication of biomedical devices and tissue regeneration scaffolds to light manipulation and energy conversion, and even to deposition of materials that act as growth platforms for nanoscale catalysis. One major limitation to wide adoption of electrospun materials is the ES hardware itself, which typically requires high voltage, electric isolation, and charged and flat deposition surfaces. In the past, fabrication of structures or materials with precisely determined mesoscale morphology has been accomplished through modification of electrode shape, use of multi-dimensional electrodes or pins, deposition onto weaving looms, hand held electrospinners that allow the user to guide deposition, or electric field manipulation by lensing elements or apertures. In this work, we demonstrate an ES system that contains multiple high voltage power supplies that are independently controlled. This system produces a novel electrostatic field that enables deposition of polymers in precise, mesoscale structures. |
| FILED | Wednesday, April 20, 2022 |
| APPL NO | 17/725251 |
| CURRENT CPC | Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0092 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333371 | Shields |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SELECT ENGINEERING SERVICES (Layton, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Eugene Shields (Layton, Utah) |
| ABSTRACT | Rigid wall shelters are used throughout the world for shipping, living quarters, and housing for electronic systems and are energy inefficient. While investigating energy-efficient technologies for rigid wall shelters the discovery was made to insulate the outside of the shelter rather than the inside. Space is often limited inside of the shelter. The invention of an external, re-deployable insulation system was developed. The present invention is an insulating system composed of three main components. The first component is multiple, purpose cut flexible envelopes filled with insulating materials (which creates a panel). The second component is multiple insulating strips that cover the joint between the panels. The final component is a weatherproof outer covering that protects the entire system from the elements. |
| FILED | Friday, February 11, 2022 |
| APPL NO | 17/650697 |
| CURRENT CPC | General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/80 (20130101) E04B 1/86 (20130101) E04B 1/92 (20130101) E04B 1/762 (20130101) Original (OR) Class Finishing Work on Buildings, e.g Stairs, Floors E04F 13/002 (20130101) Buildings or Like Structures for Particular Purposes; Swimming or Splash Baths or Pools; Masts; Fencing; Tents or Canopies, in General E04H 1/1205 (20130101) E04H 2001/1283 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 5/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333404 | McIntire et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John P. McIntire (Dayton, Ohio); Matthew Srnoyachki (Moraine, Ohio); Felicia N. Harlow (Beavercreek, Ohio) |
| ABSTRACT | Removable hands-free door pull openers are disclosed that can be attached to doors without penetrating the surface of the door. The door pull opener includes a door clamping portion configured to clamp the free edge of a door that receives a lock, and a hook portion joined to the door clamping portion. The hook portion includes a bend portion and is configured for a person to insert their forearm between one side of the door and the bend portion so that they may pull open a door without touching the door or the door pull opener with their hand. A foot pull door opener is also provided. A door latch bolt cover that covers a door latch bolt is also disclosed. |
| FILED | Tuesday, April 20, 2021 |
| APPL NO | 17/234946 |
| CURRENT CPC | Locks; Accessories Therefor; Handcuffs E05B 1/0015 (20130101) E05B 1/0053 (20130101) Original (OR) Class E05B 1/0069 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333530 | Greene et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Christopher Britton Greene (Hebron, Connecticut); James M. Donohue (Glastonbury, Connecticut); Peter AT Cocks (South Glastonbury, Connecticut) |
| ABSTRACT | A method for operating a rotating detonation engine, having a radially outer wall extending along an axis; a radially inner wall extending along the axis, wherein the radially inner wall is positioned within the radially outer wall to define an annular detonation chamber having an inlet and an outlet, wherein the method includes flowing liquid phase fuel along at least one wall of the radially inner wall and the radially outer wall in a direction from the outlet toward the inlet to cool the at least one wall and heat the liquid fuel to provide a heated liquid fuel; flowing the heated liquid fuel to a mixer at the inlet to reduce pressure of the heated liquid fuel, flash vaporize the heated liquid fuel and mix flash vaporized fuel with oxidant to produce a vaporized fuel-oxidant mixture; and detonating the mixture in the annular detonation chamber. |
| FILED | Thursday, April 15, 2021 |
| APPL NO | 17/231487 |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/24 (20130101) F02C 7/224 (20130101) Original (OR) Class F02C 7/264 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/36 (20130101) F05D 2250/141 (20130101) F05D 2260/99 (20130101) F05D 2260/232 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/32 (20130101) F23R 3/44 (20130101) F23R 3/56 (20130101) F23R 2900/03043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333916 | Nguyen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | iSenseCloud, Inc. (Milpitas, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | An-Dien Nguyen (Fremont, California); An H. Nguyen (Fremont, California) |
| ABSTRACT | A fiber optic voltage conditioner, and method therefor, generally relate to voltage conditioning. In such a fiber optic voltage conditioner, there is a laser, and an optical circulator is coupled to receive a light signal from the laser. A controller is coupled to the laser and is configured to generate first control information for wavelength-drift control of the laser. A data acquisition module is coupled to the controller and is configured to generate second control information for the controller for adjustment of the first control information. A photodetector is coupled to the optical circulator to receive a returned optical signal and is coupled to the data acquisition module to provide an analog output signal thereto. The photodetector is configured to generate the analog output signal responsive to the returned optical signal. The data acquisition module is configured to generate the second control information using the analog output signal. |
| FILED | Friday, July 01, 2022 |
| APPL NO | 17/856914 |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/165 (20130101) Original (OR) Class Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/3206 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/0612 (20130101) H01S 5/0622 (20130101) H01S 5/0687 (20130101) H01S 5/02415 (20130101) H01S 5/06837 (20130101) Transmission H04B 10/572 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333982 | Gauthier, JR. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Leo R. Gauthier, JR. (Ellicott City, Maryland); Kenneth W. Harclerode (Pasadena, Maryland) |
| ABSTRACT | Provided herein are a system and a method thereof which allows for calibrating a laser or getting characteristics of the laser by measuring the temporally and spatially resolved beam profile and power density cross-section using non-contact radiometry. An example method includes receiving a radiation beam from a light source by protrusions that protrude from a plate. The example method further includes imaging the protrusions, measuring a respective temperature of each of the protrusions based on the imaging, and profiling the radiation beam based on the measuring. |
| FILED | Saturday, February 19, 2022 |
| APPL NO | 17/676119 |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/4257 (20130101) Original (OR) Class G01J 2001/4261 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0014 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220334119 | RODLAND et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington); THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (BETHESDA, Maryland); THE UNITED STATES OF AMERICA,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Karin RODLAND (Richland, Washington); Tao LIU (Richland, Washington); Jennifer CULLEN (Bethesda, Maryland); Gyorgy PETROVICS (Bethesda, Maryland); Jacob KAGAN (Bethesda, Maryland); Sudhir SRIVASTAVA (Bethesda, Maryland) |
| ABSTRACT | Disclosed herein are methods of diagnosing or prognosing aggressive prostate cancer in a subject and methods of treating a subject with aggressive prostate cancer. For example, the methods can include measuring increased expression of aggressive prostate cancer-related molecules (such as FOLH1, SPARC, TGFB1, CAMKK2, NCOA2, EGFR, or PSA) and optionally administering a therapeutically effective amount of aggressive prostate cancer therapy. |
| FILED | Wednesday, August 19, 2020 |
| APPL NO | 17/634626 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6848 (20130101) G01N 33/57434 (20130101) Original (OR) Class G01N 2333/495 (20130101) G01N 2333/948 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220334131 | Schwartz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ELEVEN P15 INC. (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David A. Schwartz (Denver, Colorado); Ivana V. Yang (Denver, Colorado); Susan k. Mathal (Dallas, Texas) |
| ABSTRACT | Disclosed herein are biomarkers related to preclinical pulmonary fibrosis and methods of identifying the same. In embodiments, the biomarkers are proteins. In embodiments, the biomarkers are transcripts. |
| FILED | Monday, May 18, 2020 |
| APPL NO | 17/600876 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/496 (20130101) A61K 31/4418 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) Original (OR) Class G01N 2800/12 (20130101) G01N 2800/7052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220334162 | Cox et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Combat Capabilities Development Command, Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kevin C. Cox (Gate City, Virginia); David H. Meyer (Burtonsville, Maryland); Paul D. Kunz (Washington, District of Columbia) |
| ABSTRACT | Apparatuses and methods are provided that are directed to detecting electric, magnetic, or electromagnetic fields by employing atoms excited to Rydberg states coupled to radio-frequency circuits that include waveguides. |
| FILED | Wednesday, April 14, 2021 |
| APPL NO | 17/230346 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 29/0885 (20130101) Original (OR) Class Antennas, i.e Radio Aerials H01Q 1/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220334243 | DeAngelus et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Marianne A. DeAngelus (Somerville, Massachusetts); Justin Goodwin (Lincoln, Massachusetts); Neela Kaushik (Cambridge, Massachusetts); Anthony Opipari (Ann Arbor, Michigan); Taylor Killian (Toronto, Canada) |
| ABSTRACT | Described herein are systems for detecting a representation of an object in a radio frequency (RF) image. The system transmits one or more first RF signals toward an object, and receives one or more second RF signals, associated with the one or more transmitted RF signals, that have been reflected from the object. The system determines a plurality of first feature maps corresponding to a RF image associated with the one or more second RF signals. The system combines the plurality of first feature maps. The system further detects a representation of the object in the RF image based at least in part on the combined plurality of first feature maps. |
| FILED | Wednesday, March 31, 2021 |
| APPL NO | 17/219837 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/89 (20130101) Original (OR) Class G01S 13/867 (20130101) Image or Video Recognition or Understanding G06V 10/82 (20220101) G06V 10/806 (20220101) G06V 10/7715 (20220101) G06V 2201/05 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220334312 | Preble et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rochester Institute of Technology (Rochester, New York); Air Force Research Laboratory (Rome, New York) |
| ASSIGNEE(S) | Rochester Institute of Technology (Rochester, New York); Air Force Research Laboratory (Rome, New York) |
| INVENTOR(S) | Stefan Preble (Pittsford, New York); Gregory Bond (Newfields, New Hampshire); John Serafini (Rochester, New York); Matthew van Niekerk (North Chili, New York); Thomas Palone (Rochester, New York); Michael Fanto (Rome, New York); Mario J. Ciminelli (Rochester, New York) |
| ABSTRACT | Disclosed is a method and system applicable to attaching a single or multiple optical fibers in sequence to a photonic integrated circuit enabling precise control of optical fibers and/or multiple types of optical fibers and/or at any pitch. The system and method provide optical alignment and in situ attachment of one or more optical fibers to a photonic integrated circuit chip using a photo-curable adhesive, wherein curing light is delivered to the adhesive by the optical fiber being attached. |
| FILED | Thursday, April 14, 2022 |
| APPL NO | 17/720989 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/2555 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220334313 | Su et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Analog Photonics LLC (Boston, Massachusetts) |
| ASSIGNEE(S) | Analog Photonics LLC (Boston, Massachusetts) |
| INVENTOR(S) | Zhan Su (Boston, Massachusetts); Erman Timurdogan (Somerville, Massachusetts); Michael Robert Watts (Hingham, Massachusetts) |
| ABSTRACT | A polarization rotator structure includes: a first core structure formed at a first layer, extending from the first end to a second end, and a second core structure formed at a second layer that is at a different depth than the first layer and formed in proximity to the first core structure. The first core structure and the second core structure provide mode hybridization between at least two orthogonally polarized waveguide modes of the PRS. An optical splitter structure is optically coupled at a first end to the second end of the PRS, and optically coupled at a second end to at least two optical waveguides, and includes: a first core structure that is contiguous with at least one of the first or second core structures of the PRS, and a second core structure that is separate from both of the first and second core structures of the PRS. |
| FILED | Wednesday, June 29, 2022 |
| APPL NO | 17/852769 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/14 (20130101) G02B 6/126 (20130101) G02B 6/276 (20130101) G02B 6/2726 (20130101) G02B 6/2766 (20130101) Original (OR) Class G02B 6/2773 (20130101) G02B 6/12004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220335135 | McGraw et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RAM Laboratories, Inc. (San Diego, California) |
| ASSIGNEE(S) | RAM Laboratories, Inc. (San Diego, California) |
| INVENTOR(S) | Robert Michael McGraw (Del Mar, California); John Darragh Geddes (San Diego, California) |
| ABSTRACT | An embedded software analyzer (ESA) detects vulnerabilities in software, such as embedded software items (e.g., software that is pre-loaded onto a device or component). Vulnerabilities may include flaws, glitches, weaknesses, and/or other elements that may prevent correct operation or allow an attacker to access or exploit the software (and/or associated devices, components, systems, etc.) The ESA may utilize techniques such as fuzzing and symbolic execution to identify vulnerabilities. The ESA may predict vulnerabilities and prioritize analysis based on the prediction. The ESA may use smart seeding to optimize fuzzing or other analysis. Such smart seeding may include generating optimized inputs for a particular software item. The ESA may apply machine learning to perform, optimize, and/or otherwise implement such analysis techniques. |
| FILED | Tuesday, November 30, 2021 |
| APPL NO | 17/537720 |
| CURRENT CPC | Electric Digital Data Processing G06F 11/3684 (20130101) G06F 21/577 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220335181 | BOLANDER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sentient Science Corporation (Buffalo, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nathan BOLANDER (Idaho Falls, Idaho); Rajasekhar V. Pulikollu (Nashville, Tennessee); Behrooz Jalalahmadi (Idaho Falls, Idaho) |
| ABSTRACT | A system and method for determining surface contact fatigue life may use a finite element method to determine when components, such as a power transmission component, may fail in operation. The method may generate a finite element model based on the material parameters related to a power transmission component, generate a surface pressure time history for a loading event based on one or more loading parameters, determine, based on the surface pressure time history for a loading event, a finite element solution that describes stress in the grain structure, calculate damage in the finite element solution using a damage model, and determine whether a damage threshold is exceeded. |
| FILED | Tuesday, February 01, 2022 |
| APPL NO | 17/590035 |
| CURRENT CPC | Gearing F16H 2057/0087 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 13/022 (20130101) Electric Digital Data Processing G06F 17/18 (20130101) G06F 30/23 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220336379 | Sain et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Patrick M. Sain (Torrance, California); William Paul Posey (Inlet Beach, Florida) |
| ABSTRACT | A physically unclonable function (PUF) device includes capacitor array couple to an electronic device. The capacitor array includes a plurality of parallel conductive elements coupled to a dielectric material having a spatially varying permittivity to define array of randomly valued capacitors. |
| FILED | Monday, April 19, 2021 |
| APPL NO | 17/234402 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/44 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/481 (20130101) H01L 23/573 (20130101) Original (OR) Class H01L 23/5223 (20130101) H01L 23/5226 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3278 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220336589 | Koeck et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Franz A. Koeck (Tempe, Arizona); Robert Nemanich (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Franz A. Koeck (Tempe, Arizona); Robert Nemanich (Scottsdale, Arizona) |
| ABSTRACT | Electronic devices and more particularly diamond-based electronic devices and corresponding contact structures are disclosed. Electrical contact structures to diamond layers, including n-type, phosphorus doped single-crystal diamond are disclosed. In particular, electrical contact structures are formed through an arrangement of one or more nanostructured carbon layers with high nitrogen incorporation that are provided between metal contacts and n-type diamond layers in diamond-based electronic devices. Nanostructured carbon layers may be configured to mitigate reduced phosphorus incorporation in n-type diamond layers, thereby providing low specific contact resistances for corresponding devices. Diamond p-i-n diodes for direct electron emission applications are also disclosed that include electrical contact structures with nanostructured carbon layers. |
| FILED | Friday, July 01, 2022 |
| APPL NO | 17/810379 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/0665 (20130101) H01L 29/868 (20130101) H01L 29/1602 (20130101) Original (OR) Class H01L 29/6603 (20130101) H01L 29/6609 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220336689 | Derkacs |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SolAero Technologies Corp. (Albuquerque, New Mexico) |
| ASSIGNEE(S) | SolAero Technologies Corp. (Albuquerque, New Mexico) |
| INVENTOR(S) | Daniel Derkacs (Albuquerque, New Mexico) |
| ABSTRACT | A multijunction solar cell includes an upper solar subcell, a bottom solar subcell adjacent to the upper solar subcell, a layer of light scattering elements below and directly adjacent to the bottom solar subcell, and a metallic layer disposed below and adjacent to the layer of light scattering elements. |
| FILED | Friday, July 01, 2022 |
| APPL NO | 17/856667 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0547 (20141201) H01L 31/0725 (20130101) Original (OR) Class H01L 31/0735 (20130101) H01L 31/1844 (20130101) H01L 31/02363 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220336822 | Huang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Yu Huang (Los Angeles, California); Zipeng Zhao (Los Angeles, California) |
| ABSTRACT | Provided herein are improved Pt-based electrochemical catalyst (or electrocatalyst) for ORR, exhibiting a combination of high activity and high stability, along with reduced usage of scarce Pt. The Pt-based electrocatalyst is loaded on a catalyst support, which is developed through carbon engineering to impart improved performance to the Pt-based electrocatalyst. |
| FILED | Thursday, September 24, 2020 |
| APPL NO | 17/762663 |
| CURRENT CPC | Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/02 (20130101) C22F 1/14 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/923 (20130101) Original (OR) Class H01M 4/926 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220336933 | NARITA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasedena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kai NARITA (Pasadena, California); Julia R. GREER (Pasadena, California) |
| ABSTRACT | A method of interrogating an electrochemical cell includes: applying a positive direct current to the electrochemical cell for a first time period, wherein the positive direct current is characterized by a first magnitude; applying a negative direct current to the electrochemical cell for a second time period, wherein the negative direct current is characterized by a second magnitude; wherein the first and second time periods have a combined duration of less than 2 seconds; wherein the second magnitude is equal to or within 50% of the first magnitude; recording cell resistance data of the electrochemical cell during each time period; and analyzing the cell resistance data to determine at least one of: (i) state of charge of the electrochemical cell; (ii) state of health of the electrochemical cell; and (iii) the resistance anisotropy of the cell. |
| FILED | Tuesday, April 12, 2022 |
| APPL NO | 17/718705 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 50/569 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220337096 | Davlantes et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Supply, Inc. (Emeryville, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher Joseph Davlantes (Oakland, California); Varun Ramaswamy (Emeryville, California) |
| ABSTRACT | A system for wireless power networking, preferably including one or more nodes, such as transmit nodes, receive nodes, relay nodes, and/or hybrid nodes. The system may function to form a power network (e.g., mesh network) configured to transfer power wirelessly between nodes of the system. A method for wireless power networking, preferably including transmitting power, controlling relay nodes, and/or receiving power, and optionally including optimizing power network operation. The method is preferably performed at (e.g., by one or more nodes of) the system, but can additionally or alternatively be performed by any other suitable system(s). |
| FILED | Wednesday, April 13, 2022 |
| APPL NO | 17/720084 |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 3/005 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/23 (20160201) Original (OR) Class H02J 50/50 (20160201) Transmission H04B 7/145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220337240 | Venkatesh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Suresh Venkatesh (Princeton, New Jersey); Xuyang Lu (Princeton, New Jersey); Hooman Saeidi (Princeton, New Jersey); Kaushik Sengupta (Princeton, New Jersey) |
| ABSTRACT | Disclosed is an electromagnetic-circuit co-design approach for massively reconfigurable, multifunctional, and high-speed programmable metasurfaces with integrated chip tiling. The ability to manipulate the incident electromagnetic fields in a dynamically programmable manner and at high speeds using integrated chip tiling approach is also disclosed. The scalable architecture uses electromagnetic-circuit co-design of metasurfaces where each individual subwavelength meta-element is uniquely addressable and programmable. The disclosed device comprises a large array of such meta-elements. The design relies on integrated high frequency switches designed in conjugation with meta-element for massive reconfigurability of incident amplitude and phase. The disclosed chip is multi-functional and can perform beamforming, high speed spatial light modulation, dynamic holographic projections, and wavefront manipulation. |
| FILED | Tuesday, April 05, 2022 |
| APPL NO | 17/713556 |
| CURRENT CPC | Static Stores G11C 19/28 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 11/02 (20130101) Pulse Technique H03K 17/687 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20220330832 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Fan Yang (Redwood City, California); Zihao Ou (Redwood City, California); Guosong Hong (Cambridge, Massachusetts); Xiang Wu (Redwood City, California); Paul Chong (Palo Alto, California); Huiliang Wang (Redwood City, California); Xingjun Zhu (Shanghai, China PRC) |
| ABSTRACT | Provided are methods of contacting a tissue inside a subject with light by applying an ultrasound signal to a photoexcited mechanoluminescent particle while the mechanoluminescent particle is inside the subject and in proximity to the tissue, thereby causing the mechanoluminescent particle to emit light that contacts the tissue. Provided are systems and kits for performing such methods. |
| FILED | Wednesday, November 25, 2020 |
| APPL NO | 17/642648 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0097 (20130101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 41/0057 (20130101) A61K 49/0093 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220331405 | JAMES et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bryan D. JAMES (Gainesville, Florida); Josephine ALLEN (Gainesville, Florida) |
| ABSTRACT | Disclosed herein is the use of DNA aptamer assemblies of varying DNA length, structure, and sequence to both bind to collagen and other proteins, to then act as a biocompatible, degradable, reversible, or permanent 3D crosslinkers between proteins, and to service as a biologically functional material when using the appropriate aptamer sequence. Therefore, disclosed herein are compositions comprising collagen fibers crosslinked with DNA aptamers. Also disclosed are devices and implants made from or coated with collagen fibers crosslinked with DNA aptamers. Also disclosed are methods of making collagen fibers. Also disclosed are kits for producing collagen fibers. Also disclosed herein are compositions DNA aptamers in a collagen fiber matrix that stabilizes the DNA aptamer. |
| FILED | Friday, August 28, 2020 |
| APPL NO | 17/636715 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/39 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) C12N 2310/16 (20130101) C12N 2310/3519 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220331490 | Lu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Helen H. Lu (New York, New York); Christopher Z. Mosher (New York, New York); Romare Antrobus (New York, New York); James C. Hone (New York, New York); Theanne Schiros (New York, New York); Yilin Yang (New York, New York) |
| ABSTRACT | A fibrous polymeric scaffold for soft tissue engineering comprises electrospun fibers including a polymeric blend and graphite particles embedded therein. |
| FILED | Wednesday, February 09, 2022 |
| APPL NO | 17/668332 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/443 (20130101) Original (OR) Class A61L 2430/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220331804 | Weitz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David A. Weitz (Cambridge, Massachusetts); Ralph Alexander Sperling (Cambridge, Massachusetts); Adam R. Abate (Cambridge, Massachusetts) |
| ABSTRACT | The present invention generally relates to systems and techniques for manipulating fluids and/or making droplets. In certain aspects, the present invention generally relates to droplet production. The droplets may be formed from fluids from different sources. In one set of embodiments, the present invention is directed to a microfluidic device comprising a plurality of droplet-making units, and/or other fluidic units, which may be substantially identical in some cases. Substantially each of the fluidic units may be in fluidic communication with a different source of a first fluid and a common source of a second fluid, in certain embodiments. In one aspect, substantially the same pressure may be applied to substantially all of the different sources of fluid, which may be used to cause fluid to move from the different sources into the microfluidic device. In some cases, the fluids may interact within the fluidic units, e.g., by reacting, or for the production of droplets within the microfluidic device. In some cases, the droplets may be used, for example, to form a library of droplets. |
| FILED | Friday, June 10, 2022 |
| APPL NO | 17/837840 |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 23/41 (20220101) B01F 33/3011 (20220101) B01F 33/3021 (20220101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/0268 (20130101) B01L 3/502784 (20130101) Original (OR) Class B01L 2200/0673 (20130101) B01L 2300/0816 (20130101) B01L 2300/0867 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/212 (20150401) Y10T 137/0391 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220331837 | PRYZBYLA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INVENSENSE, INC. (San Jose, California) |
| ASSIGNEE(S) | INVENSENSE, INC. (San Jose, California) |
| INVENTOR(S) | Richard PRYZBYLA (Piedmont, California); Mitchell Kline (Alameda, California); David Horsley (Berkeley, California) |
| ABSTRACT | An ultrasonic transceiver system includes a transmitter block, a receiver block, a state machine, a computer unit. The transmitter block contains circuitry configured to drive an ultrasound transducer. The receiver block contains circuitry configured to receive signals from the ultrasound transducer and convert the signals into digital data. The state machine is coupled to the transmitter and receiver blocks and contains circuitry configured to act as a controller for those blocks. The computing unit is coupled to the transmitter block, the receiver block, and the state machine and is configured to drive the transmitter block and process data received from the receiver block by executing instructions of a program. The program memory is coupled to the computing unit and is configured to store the program. The computing unit is configured to be reprogrammed with one or more additional programs stored in the program memory. |
| FILED | Monday, June 27, 2022 |
| APPL NO | 17/851002 |
| CURRENT CPC | Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/0207 (20130101) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/523 (20130101) Electric Digital Data Processing G06F 8/65 (20130101) Transmission H04B 11/00 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/30 (20130101) H04L 9/0861 (20130101) H04L 9/0869 (20130101) H04L 27/36 (20130101) H04L 67/34 (20130101) Wireless Communication Networks H04W 12/02 (20130101) H04W 12/037 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332040 | FEINBERG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Adam Walter FEINBERG (Pittsburgh, Pennsylvania); Maria STANG (Pittsburgh, Pennsylvania) |
| ABSTRACT | A method and system for additive manufacturing are provided herein. The method comprises depositing a structure material, by a nozzle (810), into a support material (808) by applying to the structure material such that the structure material flows through the nozzle. The structure material comprises a polymer and a rheological modifier. Depositing of the structure material is repeated as necessary to create an object (814). The support material is at least partially removed from object. In various examples, the method comprises varying a print parameter from a first portion of the object to a second portion of the object, moving the nozzle away from a previously deposited layer of the object when repositioning for deposition of a subsequent layer of the object, or a combination thereof. |
| FILED | Monday, October 19, 2020 |
| APPL NO | 17/754115 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/40 (20170801) B29C 64/118 (20170801) Original (OR) Class B29C 64/209 (20170801) B29C 64/321 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2083/00 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 70/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332443 | Roopnarine |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Roopnarine (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Roopnarine (New York, New York) |
| ABSTRACT | A servicing system for on-orbit spacecrafts is disclosed. The system comprises a servicing or host spacecraft configured to perform on-orbit servicing of client spacecrafts. The servicing spacecraft comprises a dedicated, deployable, boom having capture and docking mechanisms. The capture mechanism comprises one or more electromagnets spaced apart and suspended on a frame that may include means for compensating for any out of plane misalignments during capture. The client spacecraft includes a striker plate that covers an area, nominally larger than the footprint of the capture mechanism, that is sized to accommodate a capture envelope determined by the rendezvous and proximity sensing systems. The electromagnets attract the striker plate to capture the client spacecraft in order to provide on-orbit servicing. The docking system has multiple degrees of freedom that are independent of the capture system; docking is accomplished by mechanically coupling the two spacecrafts together, post capture. During docking, electrical and fluid transfer connections may also be accomplished. The servicing spacecraft further comprises a manipulator arm that may be configured to position/align the captured client spacecraft for docking, thereby permitting a very flexible, larger, capture envelope, and reducing operational complexity. |
| FILED | Monday, April 18, 2022 |
| APPL NO | 17/722605 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 15/0066 (20130101) B25J 19/02 (20130101) Cosmonautics; Vehicles or Equipment Therefor B64G 1/646 (20130101) Original (OR) Class B64G 1/1078 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332615 | Lin |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | West Virginia University (Morgantown, West Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lian-Shin Lin (Morgantown, West Virginia) |
| ABSTRACT | A method for treating wastewater comprising subjecting a sulfate containing wastewater to Fe(III) iron dosing in an anaerobic bioreactor containing one or more of an iron reducing bacteria and one or more of a sulfate reducing bacteria, and one or more of a fermentative bacteria, and adjusting a dosage of the Fe(III) iron in the anaerobic bioreactor to achieve a Fe/Sulfate molar ratio that is equal to or greater than 0.50, and removing an effluent from the anaerobic bioreactor that is a treated wastewater. A wastewater treatment system is provided having a wastewater reservoir, a ferric iron solution reservoir, an anaerobic bioreactor, and an effluent reservoir. |
| FILED | Thursday, September 24, 2020 |
| APPL NO | 17/753625 |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 3/341 (20130101) Original (OR) Class C02F 3/345 (20130101) C02F 3/346 (20130101) C02F 3/2866 (20130101) C02F 2103/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332658 | de Cote et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Shared-X LLC (Grand Cayman, Cayman Islands) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jose Antonio de Cote (Miami, Florida); Patrick Vasquez De Velasco (Lima, Peru); Enrique Monte Vasquez (Salamanca, Spain) |
| ABSTRACT | The present disclosure relates to formulations including Trichoderma isolates, as well as methods thereof. In particular embodiments, the formulation can include one or more Trichoderma isolates, in which the formulation can include solid carriers and/or liquid carriers. Such formulations can be useful for treating or protecting plants, as well as counteracting growth of pathogenic organisms in proximity to the plant. |
| FILED | Tuesday, April 12, 2022 |
| APPL NO | 17/659006 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/02 (20130101) A01N 63/38 (20200101) Organic Fertilisers Not Covered by Subclasses C05B, C05C, e.g Fertilisers From Waste or Refuse C05F 11/08 (20130101) Original (OR) Class Mixtures of Fertilisers Covered Individually by Different Subclasses of Class C05; Mixtures of One or More Fertilisers With Materials Not Having a Specific Fertilising Activity, e.g Pesticides, Soil-conditioners, Wetting Agents; Fertilisers Characterised by Their Form C05G 5/12 (20200201) C05G 5/14 (20200201) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/145 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332773 | LAWRENCE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Silk Technologies, Ltd. (Plymouth, Minnesota) |
| ASSIGNEE(S) | Silk Technologies, Ltd. (Plymouth, Minnesota) |
| INVENTOR(S) | Brian D. LAWRENCE (Plymouth, Minnesota); David W. INFANGER (Plymouth, Minnesota) |
| ABSTRACT | Described herein are methods for reducing inflammation by administration of an effective amount of silk-derived proteins (SDP) or a fraction thereof to a subject having an inflammatory condition. The methods include the treatment of inflammatory conditions and wounds, including corneal wounds, comprising the topical administration of an effective amount of SDP material as described herein. |
| FILED | Monday, February 07, 2022 |
| APPL NO | 17/666268 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/14 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 38/00 (20130101) A61K 38/012 (20130101) A61K 47/02 (20130101) A61K 47/10 (20130101) A61K 47/26 (20130101) A61K 47/34 (20130101) A61K 47/38 (20130101) A61K 47/42 (20130101) A61K 47/183 (20130101) Peptides C07K 14/43586 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332869 | YANG et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Rong YANG (Ithaca, New York); Trevor FRANKLIN (Ithaca, New York) |
| ABSTRACT | Provided are amphiphilic copolymers that include repeat units of formulas [Z]m and [P]n, wherein Z is a zwitterionic structural unit including at least one pendant heteroaromatic moiety, the heteroaromatic moiety containing a positively charged quaternary nitrogen atom (e.g., a pyridine ring), and wherein at least one negatively charged functional moiety is linked to the heteroaromatic moiety directly or through a linker, wherein the linker, where present, is an optionally substituted alkyl linker; P is a structural unit including a hydrophobic moiety, the hydrophobic moiety being a linear, branched, or cyclic fluorine-substituted C1-C20 moiety; m is an integer that is ≥1; and n is an integer that is ≥1. |
| FILED | Friday, November 12, 2021 |
| APPL NO | 17/454763 |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 212/36 (20130101) C08F 220/24 (20130101) C08F 226/06 (20130101) Original (OR) Class Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/1637 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332954 | LYNN et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David LYNN (Middleton, Wisconsin); Harshit AGARWAL (Madison, Wisconsin) |
| ABSTRACT | The present invention provides liquid crystal (LC)-infused materials and methods for detecting compounds or impurities in liquid samples using such materials. These slippery materials comprise a lubricating liquid, preferably a thermotropic liquid crystal, and a solid substrate able to immobilize or host the lubricating liquid. The portion of the substrate coated by the lubricating fluid forms a slippery surface able to allow droplets of various materials to slide off the slippery surface in a manner dependent on the chemical composition of the droplet, which can be used to detect the presence of analytes, impurities and other molecules within the droplet. |
| FILED | Wednesday, April 06, 2022 |
| APPL NO | 17/714583 |
| CURRENT CPC | Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/00 (20130101) C09D 5/16 (20130101) Original (OR) Class Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition C10M 109/00 (20130101) Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions C10N 2050/08 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/02 (20130101) C12Q 1/18 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 19/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333011 | TIAN et al. |
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| FUNDED BY |
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| APPLICANT(S) | West Virginia University Board of Governors on Behalf of West Virginia University (Morgantown, West Virginia); Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hanjing TIAN (Morgantown, West Virginia); Sheng DAI (Marietta, China PRC); Jianli HU (Morgantown, West Virginia) |
| ABSTRACT | In one aspect, the disclosure relates to multicolored carbon quantum dot nanoparticles (Cdots), “one-pot” methods of making same starting from coal and using mild reaction conditions, and applications of the same. The disclosed methods are safe and environmentally benign as well as inexpensive. Additionally, the disclosed carbon quantum dot nanoparticles are stable and have tunable properties based on reaction conditions used for their synthesis. |
| FILED | Friday, August 28, 2020 |
| APPL NO | 17/753278 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/15 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/64 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/65 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333050 | MILLER et al. |
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| FUNDED BY |
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| APPLICANT(S) | William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Jordan MILLER (Houston, Texas); Ian KINSTLINGER (Solon, Ohio); Bagrat GRIGORYAN (Spring, Texas); Samantha PAULSEN (Newton, Massachusetts) |
| ABSTRACT | Some embodiments of the disclosure disclose a process for adhering cells, beads or particles to a surface of a material. The surface may be flat or curved and can be employed in the context of patterned or 3D printed hollow channels, facilitating the recapitulation of certain aspects of physiological systems. In various embodiments, interfacial cell seeding is accomplished by locally polymerizing a carrier containing a suspension of cells along the surface with a crosslinking molecule incorporated into the target material in advance of the interfacial polymerization. Polymerization of the carrier entraps the cells into controlled configuration along the surface. The techniques disclosed herein can be utilized for tissue engineering to build engineered organs/devices suitable for implanting into living organisms. |
| FILED | Friday, April 08, 2022 |
| APPL NO | 17/716389 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 31/145 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2533/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333051 | SAWYER et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | WALLACE GREGORY SAWYER (Gainesville, Florida); THOMAS ETTOR ANGELINI (Gainesville, Florida); STEVEN CRAIG GHIVIZZANI (Gainesville, Florida); TAPOMOY BHATTACHARJEE (Gainesville, Florida); GLYN DANIEL PALMER (Gainesville, Florida) |
| ABSTRACT | A three-dimensional cell growth medium is described. The cell growth medium may comprise hydrogel particles swollen with a liquid cell growth medium to form a granular gel yield stress material which undergoes a phase transformation from a solid phase to a liquid-like phase when an applied stress exceeds the yield stress. Cells may be placed in the three-dimensional cell growth medium according to any shape or geometry, and may remain in place within the three-dimensional cell growth medium. |
| FILED | Thursday, June 16, 2022 |
| APPL NO | 17/841917 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) Original (OR) Class C12M 25/14 (20130101) C12M 25/16 (20130101) C12M 35/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) C12N 2513/00 (20130101) C12N 2527/00 (20130101) C12N 2533/30 (20130101) C12N 2535/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333144 | BADRI et al. |
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| FUNDED BY |
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| APPLICANT(S) | Abinaya BADRI (Troy, New York); Mattheos AG KOFFAS (Niskayuna, New York); Robert John LINHARDT (Albany, New York); Asher J. WILLIAMS (Boston, Massachusetts) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Abinaya BADRI (Troy, New York); Mattheos AG KOFFAS (Niskayuna, New York); Robert John LINHARDT (Albany, New York); Asher J. WILLIAMS (Boston, Massachusetts) |
| ABSTRACT | In order to produce chondroitin sulfate in an animal-free manner, engineered E. coli host cells were modified so as to reduce expression of an endogenous gene for fructosyltransferase (kfoE); reduce expression of an endogenous gene for 3′-phosphoadenosine-5′-phosphosulfate reductase (cysH); and express one or more exogenous sulfotransferases. Expression of proteins forming ATP-binding cassette transporters were also reduced to limit export of glycosaminoglycans from the cells. The recombinant microorganisms are able produce all three components identified for chondroitin sulfate production—chondroitin, sulfate donor, and sulfotransferase. These modified E. coli are capable of complete, essentially one-step biosynthesis of chondroitin sulfate at a variety of sulfation levels from simple microbial media components and glucose. This is a major advantage over current production methods that depend on the natural distribution of chondroitin sulfate types in the animal tissue. |
| FILED | Thursday, September 10, 2020 |
| APPL NO | 17/641675 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/205 (20210501) C12N 9/13 (20130101) C12N 15/70 (20130101) C12N 15/1137 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/26 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/19 (20210501) Enzymes C12Y 208/02005 (20130101) C12Y 208/02017 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333158 | Seelig et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Georg Seelig (Seattle, Washington); Richard Muscat (London, United Kingdom); Alexander B. Rosenberg (Seattle, Washington) |
| ABSTRACT | Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens. |
| FILED | Tuesday, March 15, 2022 |
| APPL NO | 17/695671 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6855 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333166 | Connolly et al. |
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| FUNDED BY |
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| APPLICANT(S) | Integrated Nano-Technologies, Inc. (Henrietta, New York) |
| ASSIGNEE(S) | Integrated Nano-Technologies, Inc. (Henrietta, New York) |
| INVENTOR(S) | Dennis M. Connolly (Rochester, New York); Tara Holz (Henrietta, New York); Vera Tannous (Penfield, New York); Christopher Kilcoin (Boulder Creek, California); Konstantin Aptekarev (Santa Cruz, California); David B. Bailey (Webster, New York); Richard S. Murante (Henrietta, New York); Nathaniel E. Wescott (West Henrietta, New York) |
| ABSTRACT | A method for preparing a sample by utilizing a shearing force in the presence of a size stabilizer to break apart the sample to obtain nucleic acid molecules in a usable size range. Once nucleic acid molecules are obtained, magnetic nanoparticles are used to concentrate and clean the nucleic acid molecules for further testing. |
| FILED | Monday, January 31, 2022 |
| APPL NO | 17/589250 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502 (20130101) B01L 2200/0631 (20130101) B01L 2300/0681 (20130101) Apparatus for Enzymology or Microbiology; C12M 47/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/066 (20130101) C12N 15/10 (20130101) C12N 15/1013 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/02 (20130101) C12Q 1/6806 (20130101) C12Q 1/6825 (20130101) Original (OR) Class C12Q 2531/113 (20130101) C12Q 2563/107 (20130101) C12Q 2563/143 (20130101) C12Q 2565/629 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/286 (20130101) G01N 2001/2866 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333234 | Sinitskii et al. |
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| FUNDED BY |
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| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexander Sinitskii (Lincoln, Nebraska); Angel Torres (Lincoln, Nebraska); Gang Li (Lincoln, Nebraska) |
| ABSTRACT | Novel synthetic methods to produce layers or films and flakes of pristine graphene, heteroatom-doped graphene, nanoporous graphene or heteroatom-doped nanoporous graphene using specially designed molecular precursors at temperatures as low as 160° C. using a chemical vapor deposition (CVD) system. The methods enable the realization of graphene-based electronics and technologies due to the low-temperature synthesis, large-area coverage, and scalability of the CVD method by taking advantage of the precursors tendency to polymerize and fuse once on the catalytic metal substrates. |
| FILED | Friday, July 01, 2022 |
| APPL NO | 17/856477 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/72 (20130101) B01J 37/0215 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/26 (20130101) Original (OR) Class C23C 16/56 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333266 | Shalaev et al. |
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| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana); Palacky University (Olomouc, Czech Republic); University of Erlangen-Nuremberg (Erlangen, Germany) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vladimir M. Shalaev (West Lafayette, Indiana); Zhaxylyk Kudyshev (West Lafayette, Indiana); Alexandra Boltasseva (West Lafayette, Indiana); Alberto Naldoni (Olomouc, Czech Republic); Alexander Kildishev (West Lafayette, Indiana); Luca Mascaretti (Olomouc, Czech Republic); Stêphán Kment (Olomouc, Czech Republic); Radek Zboril (Olomouc, Czech Republic); Jeong Eun Yoo (Erlangen, Germany); Patrik Schmuki (Erlangen, Germany) |
| ABSTRACT | A thermoplasmonic device includes a titanium film and a plurality of titanium nitride tube elements disposed on the titanium film. Each of the titanium nitride tube elements includes an open top and a titanium nitride bottom. Each of the titanium nitride tube elements has titanium nitride tubular middle portion that extends from the open top to the titanium nitride bottom. |
| FILED | Monday, May 02, 2022 |
| APPL NO | 17/734934 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 21/076 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 11/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220334312 | Preble et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rochester Institute of Technology (Rochester, New York); Air Force Research Laboratory (Rome, New York) |
| ASSIGNEE(S) | Rochester Institute of Technology (Rochester, New York); Air Force Research Laboratory (Rome, New York) |
| INVENTOR(S) | Stefan Preble (Pittsford, New York); Gregory Bond (Newfields, New Hampshire); John Serafini (Rochester, New York); Matthew van Niekerk (North Chili, New York); Thomas Palone (Rochester, New York); Michael Fanto (Rome, New York); Mario J. Ciminelli (Rochester, New York) |
| ABSTRACT | Disclosed is a method and system applicable to attaching a single or multiple optical fibers in sequence to a photonic integrated circuit enabling precise control of optical fibers and/or multiple types of optical fibers and/or at any pitch. The system and method provide optical alignment and in situ attachment of one or more optical fibers to a photonic integrated circuit chip using a photo-curable adhesive, wherein curing light is delivered to the adhesive by the optical fiber being attached. |
| FILED | Thursday, April 14, 2022 |
| APPL NO | 17/720989 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/2555 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220334451 | WU |
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| FUNDED BY |
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| APPLICANT(S) | University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hui WU (Pittsford, New York) |
| ABSTRACT | Methods of manufacturing and operating a monolithically integrated optical phase array (OPA) chip device, and the device itself. A three-dimensional (3-D) integrated optical phase array (OPA) chip device. A system of complementary metal-oxide-semiconductor (CMOS) electronics integrated with a three-dimensional integrated optical array chip device. A method of three-dimension photonic integration to improve optical power in optical phase arrays. |
| FILED | Monday, October 05, 2020 |
| APPL NO | 17/754358 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4817 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/2955 (20130101) Original (OR) Class G02F 2202/105 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220335595 | Jiang et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tianyu Jiang (Seattle, Washington); Xu Chen (Seattle, Washington); Mengying Leng (Seattle, Washington) |
| ABSTRACT | A method includes capturing an image of a powder bed with a visible light camera that shares an optical axis with a laser beam. The laser beam is configured for heating the powder bed. The method also includes increasing first intensities of first pixels of the image that are indicative of foreign objects within the image and normalizing second intensities of second pixels of the image that are indicative of uneven illumination of the powder bed. The method also includes processing the image via contrast limited adaptive histogram equalization after increasing the first intensities and after normalizing the second intensities. The method also includes using graph-based image segmentation to identify third pixels of the image that correspond to an area of the powder bed that has been processed by the laser beam and indicating the third pixels via a user interface. |
| FILED | Friday, April 15, 2022 |
| APPL NO | 17/721905 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/40 (20130101) G06T 7/0004 (20130101) Original (OR) Class G06T 7/162 (20170101) G06T 2207/20092 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220336059 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Automat Solutions, Inc. (Fremont, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xiaoliang Wang (Alameda, California); Naixin Zong (Katy, Texas); Xuejun Wang (Pleasanton, California) |
| ABSTRACT | Disclosed are systems and methods for generating candidate recipes for batch testing battery recipes in robotics laboratory equipment. In one embodiment, the candidate recipes in a batch, share the maximum number of chemicals in common, while as a batch, they utilize a minimum number of chemicals. The candidate recipes are identified by constructing a graph where an initial selection of recipes are placed at each node. The graph yields the candidate recipes in the batch. |
| FILED | Thursday, March 31, 2022 |
| APPL NO | 17/711024 |
| CURRENT CPC | Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/10 (20190201) G16C 20/70 (20190201) G16C 20/80 (20190201) G16C 60/00 (20190201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220336589 | Koeck et al. |
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| FUNDED BY |
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| APPLICANT(S) | Franz A. Koeck (Tempe, Arizona); Robert Nemanich (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Franz A. Koeck (Tempe, Arizona); Robert Nemanich (Scottsdale, Arizona) |
| ABSTRACT | Electronic devices and more particularly diamond-based electronic devices and corresponding contact structures are disclosed. Electrical contact structures to diamond layers, including n-type, phosphorus doped single-crystal diamond are disclosed. In particular, electrical contact structures are formed through an arrangement of one or more nanostructured carbon layers with high nitrogen incorporation that are provided between metal contacts and n-type diamond layers in diamond-based electronic devices. Nanostructured carbon layers may be configured to mitigate reduced phosphorus incorporation in n-type diamond layers, thereby providing low specific contact resistances for corresponding devices. Diamond p-i-n diodes for direct electron emission applications are also disclosed that include electrical contact structures with nanostructured carbon layers. |
| FILED | Friday, July 01, 2022 |
| APPL NO | 17/810379 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/0665 (20130101) H01L 29/868 (20130101) H01L 29/1602 (20130101) Original (OR) Class H01L 29/6603 (20130101) H01L 29/6609 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220336699 | Bedair |
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| FUNDED BY |
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| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Salah M. Bedair (Raleigh, North Carolina) |
| ABSTRACT | Various examples are provided related to InGaN-relaxed templates. In one example, a device structure includes a GaN layer; and a semibulk template comprising a plurality of stacked periods on the GaN layer. Each period can include a layer of InGaN and a GaN interlayer disposed on the layer of InGaN, where a thickness of the GaN interlayer of a top period of the stacked periods is greater than a thickness of the GaN interlayer of a bottom period disposed on the GaN layer. In another example, a method includes forming a GaN layer and forming a semibulk template including a plurality of stacked periods on the GaN layer. Each period can include a layer of InGaN and a GaN interlayer disposed on the layer of InGaN, where a thickness of the GaN interlayer of the top period is greater than the GaN interlayer of the bottom period. |
| FILED | Wednesday, April 20, 2022 |
| APPL NO | 17/724755 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/06 (20130101) H01L 33/007 (20130101) H01L 33/12 (20130101) Original (OR) Class H01L 33/32 (20130101) H01L 33/145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220337333 | Bernstein et al. |
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| FUNDED BY |
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| APPLICANT(S) | Liane Sarah Beland Bernstein (Cambridge, Massachusetts); Alexander Sludds (Cambridge, Massachusetts); Dirk Robert ENGLUND (Brookline, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Liane Sarah Beland Bernstein (Cambridge, Massachusetts); Alexander Sludds (Cambridge, Massachusetts); Dirk Robert ENGLUND (Brookline, Massachusetts) |
| ABSTRACT | Deep neural networks (DNNs) have become very popular in many areas, especially classification and prediction. However, as the number of neurons in the DNN increases to solve more complex problems, the DNN becomes limited by the latency and power consumption of existing hardware. A scalable, ultra-low latency photonic tensor processor can compute DNN layer outputs in a single shot. The processor includes free-space optics that perform passive optical copying and distribution of an input vector and integrated optoelectronics that implement passive weighting and the nonlinearity. An example of this processor classified the MNIST handwritten digit dataset (with an accuracy of 94%, which is close to the 96% ground truth accuracy). The processor can be scaled to perform near-exascale computing before hitting its fundamental throughput limit, which is set by the maximum optical bandwidth before significant loss of classification accuracy (determined experimentally). |
| FILED | Wednesday, February 16, 2022 |
| APPL NO | 17/673268 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/0675 (20130101) Transmission H04B 10/541 (20130101) H04B 10/614 (20130101) Multiplex Communication H04J 14/0224 (20130101) H04J 14/0234 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20220332574 | ALFONSO et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California); TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicolas ALFONSO (Los Angeles, California); Travis J. WILLIAMS (Los Angeles, California); Robert P. CURRIER (Santa Fe, New Mexico); Anthony J. CHAVEZ (Downey, California); Van K. DO (Los Angeles, California) |
| ABSTRACT | A flow reactor system for providing on-demand H2 evolution at pressure from a liquid organic hydrogen carrier and/or blends thereof includes a reactor that includes a reaction vessel having an inlet and outlet. The inlet is configured to introduce reactants into the reaction vessel, and the outlet is configured to release reaction products. The reaction vessel is configured to hold therein a catalyst system capable of catalyzing the evolution of molecular hydrogen from a liquid organic hydrogen carrier. Advantageously, the reaction vessel is configured to operate at pressures greater than or equal to 50 psig (e.g., from about 50 psig to about 10500 psig. The flow reactor system also includes a source of preheated liquid organic hydrogen carrier in fluid communication with the reactor and a purification system in fluid communication with the outlet that provides purified molecular hydrogen gas for on-demand applications. |
| FILED | Monday, April 11, 2022 |
| APPL NO | 17/717786 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 8/0278 (20130101) B01J 8/0285 (20130101) B01J 2208/0007 (20130101) B01J 2208/00061 (20130101) B01J 2208/00247 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/326 (20130101) Original (OR) Class C01B 2203/02 (20130101) C01B 2203/04 (20130101) C01B 2203/1041 (20130101) C01B 2203/1623 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332609 | Campbell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Patrick G. Campbell (Oakland, California); Jennifer M. Knipe (Oakland, California); Michael Stadermann (Pleasanton, California) |
| ABSTRACT | Disclosed here is a capacitive deionization device for removing ions from a target solution. The capacitive deionization device includes a first porous electrode, a second porous electrode, a first header plate, a second header plate, and a sealant. The second porous electrode is disposed below and spaced from the first porous electrode. The first header plate is disposed on the first porous electrode. The first header plate defines an input flow channel that is in fluidic communication with the first porous electrode. The second header plate is disposed below the second porous electrode. The second header plate defines an output flow channel that is in fluidic communication with the second porous electrode. The sealant is disposed between the first header plate and the second header plate and surrounds the first porous electrode and the second porous electrode. |
| FILED | Thursday, June 30, 2022 |
| APPL NO | 17/855614 |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/4691 (20130101) Original (OR) Class C02F 1/46109 (20130101) C02F 2001/46161 (20130101) C02F 2103/08 (20130101) C02F 2201/46115 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/02 (20130101) H01G 9/10 (20130101) H01G 9/12 (20130101) H01G 9/0029 (20130101) H01G 9/048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332666 | Hermans et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ive Hermans (Middleton, Wisconsin); William McDermott (Madison, Wisconsin); Edgard Lebron Rodriguez (Madison, Wisconsin) |
| ABSTRACT | Improved methods of oxidative dehydrogenation (ODH) of alkanes and alkylbenzenes to the corresponding olefins are disclosed. The disclosed methods use ozone (O3) to mediate the oxidative dehydrogenation reaction with high selectivity for the desired product, and no heterogeneous ODH catalyst is needed. |
| FILED | Wednesday, April 13, 2022 |
| APPL NO | 17/720081 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 5/48 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332673 | TONG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhaohui TONG (Gainesville, Florida); Hanxi BAO (Gainesville, Florida); Lin Zhang (Gainesville, Florida) |
| ABSTRACT | The present disclosure provides for methods for depolymerizing lignin to produce other useful products. For example, low molecular weight aromatic and aliphatic hydrocarbons (e.g., hydrocarbons having 8 to 20 carbon atoms (C8 to C20 hydrocarbons)) as well as oil products can be produced using methods of the present disclosure. The method can include treatment of the lignin using a catalyst composition, where the catalyst composition comprises a persulfate salt and a transition metal catalyst. |
| FILED | Tuesday, June 16, 2020 |
| APPL NO | 17/621043 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 27/053 (20130101) Acyclic or Carbocyclic Compounds C07C 41/01 (20130101) C07C 67/333 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332870 | Azoulay et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNIVERSITY OF SOUTHERN MISSISSIPPI (Hattiesburg, Mississippi); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE UNIVERSITY OF SOUTHERN MISSISSIPPI (Hattiesburg, Mississippi); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Jason D. Azoulay (Hattiesburg, Mississippi); Benjamin A. Zhang (San Mateo, California); Yi Liu (San Ramon, California) |
| ABSTRACT | The invention provides for new polymer compounds and methods for the preparation of modular narrow band gap conjugated compounds and polymers that incorporate exocyclic cross-conjugated donors or substituents, as well as novel monomer components of such polymers and the resulting products which comprise materials and useful electronic devices with novel functionality. |
| FILED | Friday, April 22, 2022 |
| APPL NO | 17/660213 |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 228/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332887 | Pellerite et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | 3M INNOVATIVE PROPERTIES COMPANY (St. Paul, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark J. Pellerite (Woodbury, Minnesota); Claire Hartmann-Thompson (Lake Elmo, Minnesota); Marina M. Kaplun (Woodbury, Minnesota); Justin P. Meyer (Oakdale, Minnesota); John P. Baetzold (North St. Paul, Minnesota); James P. DiZio (St. Paul, Minnesota); John Christopher Thomas (St. Paul, Minnesota); Steven D. Solomonson (Shoreview, Minnesota) |
| ABSTRACT | A cationic copolymer comprises the divalent monomer units: wherein: each Ar1 independently represents phenylene; each L independently represents a direct bond or wherein each R1 independently represents an alkyl group having 1 to 4 carbon atoms, and each R2 independently represents an alkylene group having from 1 to 6 carbon atoms, and each Z− represents a non-interfering anion; each Ar2 independently represents an optionally substituted divalent aryl ring, with the proviso that if L represents a direct bond, then Ar2 represents an optionally substituted cationic divalent aryl ring accompanied by Z; each R3 independently represents H or an alkyl group having 1 to 6 carbon atoms; and each D independently represents a direct bond or Ar2, wherein adjacent D and L are not both direct bonds, and wherein if L is a direct bond, then D is Ar2. The cationic copolymer can be free-radially cured and used in a membrane. |
| FILED | Thursday, August 06, 2020 |
| APPL NO | 17/634419 |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/10 (20130101) Original (OR) Class C08G 61/123 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/103 (20130101) H01M 2008/1095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332915 | Kucharzyk et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Katarzyna H. Kucharzyk (Columbus, Ohio); Morgan V. Evans (Columbus, Ohio); Emma Beasley (Columbus, Ohio) |
| ABSTRACT | Novel ways of degrading polyamides including Nylon 6 and Nylon 6,6 (polycaprolactam) are disclosed. Microorganisms originally sourced from the environment are utilized to produce an enzyme(s) useful for degrading polyamides. can be degraded by a cutinase, a lipase, or a combination thereof. |
| FILED | Monday, April 04, 2022 |
| APPL NO | 17/713220 |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 11/105 (20130101) Original (OR) Class C08J 2333/24 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/18 (20130101) Enzymes C12Y 301/01003 (20130101) C12Y 301/01074 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333254 | OLSON et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania) |
| ASSIGNEE(S) | Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania) |
| INVENTOR(S) | Luke C. OLSON (Columbia, South Carolina); Kathryn E. METZGER (Columbia, South Carolina); Edward J. Lahoda (Edgewood, Pennsylvania) |
| ABSTRACT | A method is described herein that produces UN from UF6 in at most two steps comprising UF6→intermediate→UN. The principle of the reaction is that in a first step, UF6 would be reduced to UxNy, where x may be an integer selected from 1 and 3, and y is an integer selected from 1 and 2. Reduction occurs at or near the surface of a gaseous membrane electrode where it is also in contact with a nitrogen bearing salt. In a second step, UxNy decomposes to UN and N2 gas, either in the same reactor as the first step or after removal to a separate unit for further processing. |
| FILED | Friday, September 04, 2020 |
| APPL NO | 17/753548 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/01 (20210101) Original (OR) Class C25B 1/50 (20210101) C25B 9/09 (20210101) C25B 15/083 (20210101) Nuclear Reactors G21C 3/62 (20130101) G21C 21/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333879 | PANAS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California); Bright Silicon Technologies, Inc. (San Francisco, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert Matthew PANAS (Dublin, California); Cynthia Dawn Walker PANAS (Dublin, California); Robert MCHENRY (San Francisco, California) |
| ABSTRACT | The present disclosure relates to a thermal emissivity control system. The system may have a segmented array that makes use of a thermally conductive base layer configured to be connectable to an external heat generating subsystem, with the base layer including a thermally emissive surface. The array may also have a plurality of actuation elements at least one of positioned on or adjacent to the thermally emissive surface. A plurality of movable shutter elements is disposed adjacent one another in a grid pattern, and controlled in movement by the actuation elements to create gaps of controllably varying dimension therebetween. The shutter elements control at least one of a magnitude of, or direction of, thermal radiation through the gaps. |
| FILED | Monday, April 19, 2021 |
| APPL NO | 17/234211 |
| CURRENT CPC | Fluid Dynamics, i.e Methods or Means for Influencing the Flow of Gases or Liquids F15D 1/007 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 13/02 (20130101) Original (OR) Class F28F 27/00 (20130101) F28F 2280/105 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333939 | Hegde et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GM Global Technology Operations LLC (Detroit, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bharatkumar Hegde (Bloomfield Hills, Michigan); Chen-Fang Chang (Bloomfield Hills, Michigan) |
| ABSTRACT | A method for generating energy-optimized travel routes for a motor vehicle includes one or more of the following: receiving an origin destination (OD) of the motor vehicle and an encrypted energy consumption database of the motor vehicle; generating N candidate routes for the OD; evaluating encrypted energy consumption over a route using an encrypted energy consumption database; applying at least one of homomorphic addition function or homomorphic multiplication function to the encrypted energy consumption data; and returning N candidate routes and their encrypted energy consumption to a client. |
| FILED | Thursday, April 15, 2021 |
| APPL NO | 17/231288 |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/3415 (20130101) G01C 21/3469 (20130101) Original (OR) Class G01C 21/3605 (20130101) G01C 21/3697 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/008 (20130101) H04L 9/0825 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220334540 | D'Amato et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Fernando Javier D'Amato (Niskayuna, New York); Mustafa Tekin Dokucu (Latham, New York); Hema Kumari Achanta, III (Schenectady, New York); Kalpesh Singal (Ballston Spa, New York); Masoud Abbaszadeh (Clifton Park, New York); Yuh-Shyang Wang (Pittsburgh, Pennsylvania); Karla Kvaternik (Schenectady, New York); Souransu Nandi (Niskayuna, New York); Georgios Boutselis (Niskayuna, New York) |
| ABSTRACT | Systems and methods are provided for the control of an industrial asset, such as a power generating asset. Accordingly, a cyber-attack model predicts a plurality of operational impacts on the industrial asset resulting from a plurality of potential cyber-attacks. The cyber-attack model also predicts a corresponding plurality of potential mitigation responses. In operation, a cyber-attack impacting at least one component of the industrial asset is detected via the cyber-attack neutralization module and a protected operational impact of the cyber-attack is identified based on the cyber-attack model. The cyber-attack neutralization module selects at least one mitigation response of the plurality of mitigation responses based on the predicted operational impact and an operating state of the industrial asset is altered based on the selected mitigation response. |
| FILED | Wednesday, April 14, 2021 |
| APPL NO | 17/229934 |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 15/02 (20130101) Original (OR) Class Electric Digital Data Processing G06F 9/45508 (20130101) G06F 21/554 (20130101) G06F 2221/034 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220335169 | DiMaio et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Tetramer Technologies, LLC (Pendleton, South Carolina) |
| ASSIGNEE(S) | Tetramer Technologies, LLC (Pendleton, South Carolina) |
| INVENTOR(S) | Jeffrey R. DiMaio (Pendleton, South Carolina); Zachary Hunt (Simpsonville, South Carolina); Yanina Breakiron (Clemson, South Carolina); Baris Kokuoz (Anderson, South Carolina); Bogdan Zdyrko (Clemson, South Carolina); Michael A. Schreuder (Anderson, South Carolina); Stephen D. Hudson (Westminster, South Carolina) |
| ABSTRACT | The present disclosure pertains to a tamper indicating security device, which indicates unauthorized duplication of and/or access to a variety of secure documents, technologies, products, and/or protected volumes. |
| FILED | Wednesday, May 04, 2022 |
| APPL NO | 17/736315 |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 27/08 (20130101) B32B 27/304 (20130101) B32B 2250/04 (20130101) B32B 2255/26 (20130101) B32B 2305/72 (20130101) B32B 2305/347 (20130101) B32B 2307/412 (20130101) Electric Digital Data Processing G06F 21/34 (20130101) G06F 21/73 (20130101) G06F 21/86 (20130101) Original (OR) Class G06F 21/88 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3278 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220336185 | BLOOM et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Integrated Dynamic Electron Solutions, Inc. (Pleasanton, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ruth Shewmon BLOOM (Oakland, California); Bryan Walter REED (San Leandro, California); Daniel Joseph MASIEL (Alamo, California); Sang Tae PARK (Danville, California) |
| ABSTRACT | A device may include an electron source, a detector, and a deflector. The electron source may be directed toward a sample area. The detector may receive an electron signal or an electron-induced signal. A deflector may be positioned between the electron source and the sample. The deflector may modulate an intensity of the electron source directed to the sample area according to an electron dose waveform having a continuously variable temporal profile. |
| FILED | Monday, March 07, 2022 |
| APPL NO | 17/688339 |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/28 (20130101) H01J 37/147 (20130101) H01J 37/243 (20130101) Original (OR) Class H01J 37/292 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220336200 | McHugh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Kelly McHugh (Richland, Washington); Michael Sinnwell (Iowa City, Iowa); Dushyant Barpaga (Richland, Washington) |
| ABSTRACT | Nanoporous ion emitters (nano-PIEs) materials promote ionization efficiency of an analyte during thermal ionization mass spectrometry (TIMS). The nano-PIE is a hierarchical material or a modified hierarchical material. The nano-PIE may comprise a coordination polymer (CP), a modified CP, or any combination thereof. Ionization efficiency is promoted by loading the nano-PIE and an analyte on a TIMS filament for subsequent TIMS analysis. |
| FILED | Friday, April 08, 2022 |
| APPL NO | 17/716297 |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220336687 | Sampath et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| ASSIGNEE(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| INVENTOR(S) | Walajabad S. Sampath (Fort Collins, Colorado); Amit H. Munshi (Fort Collins, Colorado); Ramesh Pandey (Fort Collins, Colorado); Akash Shah (Fort Collins, Colorado); Tushar Shimpi (Windsor, Colorado) |
| ABSTRACT | The present disclosure relates to thin-film solar cells with improved efficiency and methods for producing thin-film solar cells having increased efficiency. In certain embodiments, thin-film solar cells having an efficiency of over 21%, over 20%, over 19%, over 15%, over 10%, etc. has been obtained using the methods of the disclosure. In certain aspects, the methods of the disclosure use passivation, passivating oxides, and/or doping treatments in increase the efficiency of the thin-film solar cells; e.g., CdTe-based thin-film solar cells. |
| FILED | Friday, June 10, 2022 |
| APPL NO | 17/837755 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/1832 (20130101) H01L 31/1868 (20130101) H01L 31/02167 (20130101) H01L 31/02966 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220336802 | Xin |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Huolin Xin (Irvine, California) |
| ABSTRACT | The present invention features a new way of doping layered cathode materials in lithium ion batteries. Using a “high entropy” doping strategy, more than four impurity elements can be introduced to the host materials. The present invention applies this high entropy doping strategy to a high nickel content layered oxide material and a lithium-manganese rich material. This new high entropy doping strategy allows the layered oxide materials used in the positive electrode of lithium ion battery to achieve high energy density, long life cycle and reduced reliance on the expensive and toxic cobalt, all of which are desired attributes for improving the performance of lithium ion batteries and reducing their cost. |
| FILED | Friday, June 25, 2021 |
| APPL NO | 17/358460 |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 53/50 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/505 (20130101) H01M 4/525 (20130101) Original (OR) Class H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220336804 | Xin |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Huolin Xin (Irvine, California) |
| ABSTRACT | The present invention features a new way of doping layered cathode materials in lithium ion batteries. Using a “high entropy” doping strategy, more than four impurity elements can be introduced to the host materials. The present invention applies this high entropy doping strategy to a high nickel content layered oxide material and a lithium-manganese rich material. This new high entropy doping strategy allows the layered oxide materials used in the positive electrode of lithium ion battery to achieve high energy density, long life cycle and reduced reliance on the expensive and toxic cobalt, all of which are desired attributes for improving the performance of lithium ion batteries and reducing their cost. |
| FILED | Friday, October 22, 2021 |
| APPL NO | 17/508540 |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 53/50 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/505 (20130101) H01M 4/525 (20130101) Original (OR) Class H01M 10/0525 (20130101) H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220336813 | HERLE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Applied Materials, Inc. (Santa Clara, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | SUBRAMANYA P. HERLE (Mountain View, California); Gao LIU (Piedmont, California); Jie GUAN (San Jose, California); James CUSHING (Santa Clara, California); Ajey M. JOSHI (San Jose, California); Tianyu ZHU (El Cerrito, California); Chen FANG (Kensington, California); Thanh-Nhan TRAN (Berkeley, California) |
| ABSTRACT | Polyimide binders and their polyamic precursors to be used for forming electrode structures are provided. The designed polyamic binder precursors are water-soluble, and the resulting polyimide binders are mechanically strong, electrochemically and thermally stable. The properties of polyimide binders have led to significant improvement in electrode compatibility towards new manufactural processes. |
| FILED | Thursday, April 14, 2022 |
| APPL NO | 17/659302 |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/1046 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/133 (20130101) H01M 4/134 (20130101) H01M 4/0404 (20130101) H01M 4/622 (20130101) Original (OR) Class H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220336846 | XIAO et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan) |
| ASSIGNEE(S) | GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan) |
| INVENTOR(S) | Xingcheng XIAO (Troy, Michigan); Hongliang WANG (Sterling Heights, Michigan) |
| ABSTRACT | A method for restoring a solid-state electrolyte layer having passivation layers formed on one or more surfaces thereof is provided. The method includes exposing one or more surface regions of the solid-state electrolyte layer by removing the passivation layers using a surface treatment process. The surface treatment process may include heating at least one portion of the passivation layers or an interface between the solid-state electrolyte layer and the passivation layers to a temperature that is at least 5% greater than a decomposition temperature of the passivation layers. The surface treatment process may use be a laser surface treatment process or a plasma surface treatment process. In each instance, the surface treatment process may be a thermal vaporization process and/or may cause volumetric expansion of the passivation layers and/or may cause thermal stress at an interface between the solid-state electrolyte layer and the passivation layers. |
| FILED | Wednesday, April 14, 2021 |
| APPL NO | 17/230800 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/54 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2300/0071 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220336847 | Ye et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jianchao Ye (Tracy, California); Jose Ali Espitia (Livermore, California); John Miller (Walnut Creek, California); Marissa Wood (Oakland, California) |
| ABSTRACT | A product includes a solid state electrolyte particle coated with a coating consisting essentially of metal oxide. A method includes depositing a coating on a solid state electrolyte particle by atomic layer deposition. A method includes fabricating a product using a plurality of solid state electrolyte particles coated with a coating consisting essentially of metal oxide. |
| FILED | Thursday, April 15, 2021 |
| APPL NO | 17/231886 |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 25/006 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/40 (20130101) C23C 16/45555 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/62 (20130101) H01M 10/0525 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2004/028 (20130101) H01M 2300/0094 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220336849 | Visco et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PolyPlus Battery Company (Berkeley, California) |
| ASSIGNEE(S) | PolyPlus Battery Company (Berkeley, California) |
| INVENTOR(S) | Steven J. Visco (Berkeley, California); Yevgeniy S. Nimon (Danville, California); Bruce D. Katz (Moraga, California) |
| ABSTRACT | An intermediary solid electrolyte structure having a Li ion conducting solid electrolyte layer with a thin phosphorus nitride film covering provides protection of the solid electrolyte surfaces against reaction with moisture during sulfide glass solid electrolyte storage, transportation, and cell assembly in a dry room atmosphere. |
| FILED | Friday, February 11, 2022 |
| APPL NO | 17/650770 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/134 (20130101) H01M 10/0525 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2300/0071 (20130101) H01M 2300/0094 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220336857 | Liu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Gao Liu (Piedmont, California) |
| ABSTRACT | The present invention provides for an amphiphilic molecule having a profluorinated alkyl-methyloligoethyleneoxide structure. The present invention also provides for an electrolyte composition comprising an amphiphilic molecule of the present invention, an electrolyte solvent, and a lithium salt. |
| FILED | Monday, May 02, 2022 |
| APPL NO | 17/734585 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 43/126 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0567 (20130101) Original (OR) Class H01M 10/0569 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220336864 | HUANG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Urban Electric Power Inc. (Pearl River, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jinchao HUANG (Pearl River, New York); Gautam YADAV (Pearl River, New York); Jungsang CHO (Pearl River, New York); Meir WEINER (Pearl River, New York); Aditya UPRETI (Pearl River, New York); Sanjoy BANERJEE (Pearl River, New York); Michael NYCE (Pearl River, New York) |
| ABSTRACT | A battery comprises an anode, a cathode, and a polymer electrolyte disposed between the anode and the cathode. The polymer electrolyte can include an inert hydrophilic polymer matrix impregnated with an aqueous electrolyte. The hydrophilic polymer matrix can include a polar vinyl monomer, an initiator, and a cross-linker. A gassing inhibitor can be included in the polymer electrolyte to help avoid issues with overcharging of the electrodes. |
| FILED | Thursday, September 03, 2020 |
| APPL NO | 17/640449 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/32 (20130101) H01M 4/34 (20130101) H01M 4/244 (20130101) H01M 4/628 (20130101) H01M 10/36 (20130101) Original (OR) Class H01M 50/44 (20210101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220337036 | Fitzpatrick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | TRANSIENT PLASMA SYSTEMS, INC. (Torrance, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph F. Fitzpatrick (Glendale, California); Mark A. Thomas (Redondo Beach, California); Alonzo Gomez (Los Angeles, California); Jason M. Sanders (La Crescenta, California) |
| ABSTRACT | A plasma assisted spark ignition system includes an ignitor and a power supply. The first ignitor includes: a casing having a first end, a second end that forms a first electrode, and a longitudinally extending passage, a second electrode which protrudes longitudinally outward from an opening at the second end of the casing and laterally spaced inwardly to form a spark gap, and an electrical insulator (dielectric) surrounding a portion of the second electrode, and which has a terminus that is at least closely spaced to an interior surface of the end of the casing. The power supply supplies a plurality of voltage pulses to the ignitor per ignition event to generate a flash over on the dielectric. Subsequent pulses in an ignition event may be at lower amplitude than an initial pulse in the ignition event. Pulses may, for example, have a duration on the order of a nanosecond. |
| FILED | Monday, April 18, 2022 |
| APPL NO | 17/722943 |
| CURRENT CPC | Spark Gaps; Overvoltage Arresters Using Spark Gaps; Sparking Plugs; Corona Devices; Generating Ions to be Introduced into Non-enclosed Gases H01T 15/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220337317 | DeVore et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Peter Thomas Setsuda DeVore (Livermore, California); Apurva Shantharaj Gowda (Mountain View, California); David Simon Perlmutter (Oakland, California); Alexander Thomas Wargo (Livermore, California); Jason Thomas Chou (Walnut Creek, California) |
| ABSTRACT | Devices, methods for analog-to-digital converters (ADCs) that perform high-dynamic range measurements based on optical techniques are disclosed. In one example aspect, an optical encoder includes a polarization rotator configured to receive a train of optical pulses, and an electro-optic (EO) modulator coupled to an output of the polarization rotator. The EO modulator is configured to receive a radio frequency (RF) signal and to produce a phase modulated signal in accordance with the RF signal. The optical encoder also includes a polarizing beam splitter coupled to the output of the EO modulator; and an optical hybrid configured to receive two optical signals from the polarizing beam splitter and to produce four optical outputs that are each phase shifted with respect to one another. |
| FILED | Friday, July 17, 2020 |
| APPL NO | 17/634522 |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 1/60 (20130101) Transmission H04B 10/2575 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220337788 | O'Neill et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mission Support and Tests Services, LLC (Las Vegas, Nevada) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mary D. O'Neill (Santa Barbara, California); Mark Morey (Las Vegas, Nevada); David Terry (Santa Barbara, California) |
| ABSTRACT | A system for monitoring for a gas leak from a gas containing structure. The system includes a lens that directs an image of a scene of interest through an optical filter to a detector. The filter, associated with the lens, has one or more passbands that pass wavelengths which match one or more emission or reflectively wavelengths of the gas being monitored. A detector receives the image after the image passes through the lens and the filter. The detector generates image data representing the scene including the gas containing structure. A processor is configured to process the image data by executing machine executable code stored on a memory. The machine executable code processes the image data to identify turbulence flows in the image data such that a turbulence flow indicates a gas leak. The code generates and sends an alert in response to the identification of a turbulence flow. |
| FILED | Tuesday, June 21, 2022 |
| APPL NO | 17/845888 |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 3/04 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6218 (20130101) Image Data Processing or Generation, in General G06T 7/246 (20170101) G06T 2207/30232 (20130101) Image or Video Recognition or Understanding G06V 10/147 (20220101) G06V 20/52 (20220101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/12 (20130101) Pictorial Communication, e.g Television H04N 5/272 (20130101) H04N 5/2256 (20130101) H04N 7/183 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20220331329 | SHAPIRO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, Baltimore (Baltimore, Maryland); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul S. SHAPIRO (Baltimore, Maryland); Alexander D. MACKERELL, JR. (Baltimore, Maryland); Jeffrey D. HASDAY (Timonium, Maryland) |
| ABSTRACT | Compounds that inhibit p38α MAPK protein, and methods of using the same, are provided for treating or preventing diseases such as cancer or inflammatory diseases. |
| FILED | Monday, May 09, 2022 |
| APPL NO | 17/740248 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/54 (20130101) A61K 31/5375 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/02 (20180101) A61P 29/00 (20180101) A61P 31/00 (20180101) A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220331517 | Carlsen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Indiana University (Bloomington, Indiana); The United States Government as represented by the Department of Veterans Affairs (Washington D.C., District of Columbia); Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | The Trustees of Indiana University (Bloomington, Indiana); The United States Government as represented by the Department of Veterans Affairs (Washington D.C., District of Columbia) |
| INVENTOR(S) | Mark S. Carlsen (Lafayette, Indiana); Gregory S. Eakins (West Lafayette, Indiana); Robert M. Everly (West Lafayette, Indiana); Catherine L. McIntyre (West Lafayette, Indiana); Phillip J. Wyss (West Lafayette, Indiana); Robert L. Bacallao (Indianapolis, Indiana) |
| ABSTRACT | Syringe pump controllers which memorialize the process of hydrodynamic isotonic saline delivery (HIFD) to reverse acute kidney injury are disclosed. In some embodiments, the syringe pump controllers are constructed to control syringe pump(s) to deliver a defined volume of saline at a prescribed perfusion rate while monitoring renal vein pressures during the infusion. In some embodiments, the syringe pump controllers have safety features designed to shut off the infusion if the renal vein pressure goes above set safety limits. |
| FILED | Thursday, September 17, 2020 |
| APPL NO | 17/760657 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/14546 (20130101) A61M 5/16854 (20130101) Original (OR) Class A61M 2210/1082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220332692 | Compadre et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BIOVENTURES, LLC (Little Rock, Arkansas); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | BIOVENTURES, LLC (Little Rock, Arkansas); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Cesar Compadre (Little Rock, Arkansas); Philip J. Breen (Little Rock, Arkansas); Martin Hauer-Jensen (Little Rock, Arkansas); Kottayil Varughese (Little Rock, Arkansas); K. Sree Kumar (Rockville, Maryland) |
| ABSTRACT | Tocol derivative compounds, compositions comprising these tocol derivatives and methods of using the tocol derivatives are provided herein. Specifically the tocol derivatives have a partially unsaturated hydrocarbon tail and are thus distinct from the tocopherols. The hydrocarbon tails do not have a trans carbon-carbon double bond in the second isoprene unit of the hydrocarbon tail and are distinct from the tocotrienols. The compounds are expected to allow improved interaction with the a-tocopherol transfer protein receptor than the tocotrienols and better bioactivity than the tocopherols. |
| FILED | Tuesday, July 05, 2022 |
| APPL NO | 17/857879 |
| CURRENT CPC | Heterocyclic Compounds C07D 311/58 (20130101) C07D 311/72 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220333159 | Feinstein et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States Government As Represented By The Department of Veterans Affairs (Washington, District of Columbia); THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Douglas Feinstein (Chicago, Illinois); Anne Boullerne (Chicago, Illinois) |
| ABSTRACT | Disclosed herein, are methods of detecting multiple sclerosis in a subject by measuring relative abundances of multiple oral microbiota in sample. Also, disclosed herein are methods of treatment and prophylaxis of MS. |
| FILED | Thursday, April 07, 2022 |
| APPL NO | 17/715187 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/285 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20220335181 | BOLANDER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sentient Science Corporation (Buffalo, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nathan BOLANDER (Idaho Falls, Idaho); Rajasekhar V. Pulikollu (Nashville, Tennessee); Behrooz Jalalahmadi (Idaho Falls, Idaho) |
| ABSTRACT | A system and method for determining surface contact fatigue life may use a finite element method to determine when components, such as a power transmission component, may fail in operation. The method may generate a finite element model based on the material parameters related to a power transmission component, generate a surface pressure time history for a loading event based on one or more loading parameters, determine, based on the surface pressure time history for a loading event, a finite element solution that describes stress in the grain structure, calculate damage in the finite element solution using a damage model, and determine whether a damage threshold is exceeded. |
| FILED | Tuesday, February 01, 2022 |
| APPL NO | 17/590035 |
| CURRENT CPC | Gearing F16H 2057/0087 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 13/022 (20130101) Electric Digital Data Processing G06F 17/18 (20130101) G06F 30/23 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220336866 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yat Li (Santa Cruz, California); Dun Lin (Santa Cruz, California) |
| ABSTRACT | An aqueous rechargeable zinc-iodine battery includes an aqueous electrolyte solution including zinc-iodine; a zinc anode; and a double-layered cathode having: a conductive substrate, and an adsorptive layer disposed over the conductive substrate. |
| FILED | Thursday, April 14, 2022 |
| APPL NO | 17/720617 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/366 (20130101) H01M 4/583 (20130101) H01M 4/608 (20130101) H01M 10/365 (20130101) Original (OR) Class H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20220332673 | TONG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhaohui TONG (Gainesville, Florida); Hanxi BAO (Gainesville, Florida); Lin Zhang (Gainesville, Florida) |
| ABSTRACT | The present disclosure provides for methods for depolymerizing lignin to produce other useful products. For example, low molecular weight aromatic and aliphatic hydrocarbons (e.g., hydrocarbons having 8 to 20 carbon atoms (C8 to C20 hydrocarbons)) as well as oil products can be produced using methods of the present disclosure. The method can include treatment of the lignin using a catalyst composition, where the catalyst composition comprises a persulfate salt and a transition metal catalyst. |
| FILED | Tuesday, June 16, 2020 |
| APPL NO | 17/621043 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 27/053 (20130101) Acyclic or Carbocyclic Compounds C07C 41/01 (20130101) C07C 67/333 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20220333916 | Nguyen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | iSenseCloud, Inc. (Milpitas, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | An-Dien Nguyen (Fremont, California); An H. Nguyen (Fremont, California) |
| ABSTRACT | A fiber optic voltage conditioner, and method therefor, generally relate to voltage conditioning. In such a fiber optic voltage conditioner, there is a laser, and an optical circulator is coupled to receive a light signal from the laser. A controller is coupled to the laser and is configured to generate first control information for wavelength-drift control of the laser. A data acquisition module is coupled to the controller and is configured to generate second control information for the controller for adjustment of the first control information. A photodetector is coupled to the optical circulator to receive a returned optical signal and is coupled to the data acquisition module to provide an analog output signal thereto. The photodetector is configured to generate the analog output signal responsive to the returned optical signal. The data acquisition module is configured to generate the second control information using the analog output signal. |
| FILED | Friday, July 01, 2022 |
| APPL NO | 17/856914 |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/165 (20130101) Original (OR) Class Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/3206 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/0612 (20130101) H01S 5/0622 (20130101) H01S 5/0687 (20130101) H01S 5/02415 (20130101) H01S 5/06837 (20130101) Transmission H04B 10/572 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Smithsonian Institution (SI)
| US 20220336051 | Green et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard E. Green (Santa Cruz, California); Samuel H. Vohr (Santa Cruz, California) |
| ABSTRACT | Disclosed are methods for testing biological samples containing genomic nucleic acids obtained from an organism having a genome, such as a human genome. It is often desirable to analyze a DNA sample or more than one, different DNA samples, to determine whether the sample comes from one individual or two individuals. The present method requires very low amounts of DNA and can use partial sequences of DNA fragments. Partial sequences are analyzed for the presence of polymorphisms (e.g. SNP's) that can be mapped to a reference SNP map. The distance between similar SNPS, which are genetically linked, can be used to statistically determine a likelihood of identity of individuality in a sample. |
| FILED | Friday, April 29, 2022 |
| APPL NO | 17/733866 |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) G16B 20/20 (20190201) G16B 20/40 (20190201) G16B 30/00 (20190201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 20220332527 | Perry-Eaton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Wayne R. Perry-Eaton (Leesburg, Virginia); George W. Potts, Jr. (Upper Marlboro, Maryland); Daniel Radtke (Madison, Wisconsin) |
| ABSTRACT | An automated system for transferring articles from a container. An item transfer system includes a frame configured to receive a first tray and a second tray, a movable paddle assembly, a frame, and a plurality of actuators. The system is configured to transfer articles from the first tray to the second tray by an automated process including securing the articles within the first tray with the paddle assembly, moving a lifting assembly or an item support platform such that the articles are in a slidable configuration relative to the first tray, moving the paddle assembly and/or the item support platform in one or more linear translations to remove the items from the first tray and place the items above the second tray, and releasing the items into the second tray. |
| FILED | Friday, July 01, 2022 |
| APPL NO | 17/810571 |
| CURRENT CPC | Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 3/008 (20130101) Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors B65G 65/04 (20130101) Original (OR) Class B65G 65/38 (20130101) B65G 2207/46 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 20220335577 | Hayes et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Matthew John Francis Hayes (McKinney, Texas); Dustin Hamill (McKinney, Texas); James Robarge (McKinney, Texas); Christopher Beardsley (McKinney, Texas); Carl Magnuson (McKinney, Texas) |
| ABSTRACT | A system, and method of operating the same detects moving targets in images and performs image turbulence correction. The system includes an automatic target recognizer (ATR) system including a database. The ATR includes a feature extractor and processor arranged to detect a plurality of reference features associated with targets within image frames, and calculate a position of the plurality of reference features. The system includes an image processor arranged to receive the position, demosaic the image frames into a plurality of video tiles, iteratively process the video tiles for turbulence correction to generate turbulence corrected video tiles associated with acquired targets; convert the turbulence corrected video tiles into a single video frame tile including turbulence degradation correction; and mosaic each of the single video frame tiles to generate a full field of view turbulence corrected video stream. |
| FILED | Wednesday, April 14, 2021 |
| APPL NO | 17/230621 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/9021 (20190501) Image Data Processing or Generation, in General G06T 3/4038 (20130101) G06T 5/003 (20130101) Original (OR) Class G06T 7/246 (20170101) G06T 2207/10024 (20130101) G06T 2207/10048 (20130101) G06T 2207/20132 (20130101) G06T 2207/30196 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, October 20, 2022.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
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HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-applications-20221020.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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