FedInvent™ Patent Applications
Application Details for Thursday, December 15, 2022
This page was updated on Saturday, December 17, 2022 at 07:10 PM GMT
Department of Health and Human Services (HHS)
| US 20220394973 | Ojima et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| ASSIGNEE(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| INVENTOR(S) | Iwao Ojima (Port Jefferson, New York); Maurizio Del Poeta (Mount Sinai, New York); Cristina Lazzarini (East Setauket, New York); Krupanandan Haranahalli (Setauket, New York); Yi Sun (Mount Sinai, New York) |
| ABSTRACT | The present invention provides a compound having the structure: and use of the compound for inhibiting the growth of or killing |
| FILED | Friday, June 10, 2022 |
| APPL NO | 17/837548 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/28 (20130101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 31/195 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220395200 | KOVATCHEV et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | BORIS P. KOVATCHEV (Charlottesville, Virginia); CHIARA FABRIS (Charlottesville, Virginia) |
| ABSTRACT | A method, system, and computer-readable medium for providing a real-time estimation of laboratory glycosylated hemoglobin (HbA1c) at one or more intervals. The real-time estimation is conferred as a value of estimated, time variable A1e (eA1c) based on daily continuous glucose monitoring (CGM)-derived time in target range (TIR) (CGM-TIR). The eA1c value is adjusted based on a sole laboratory HbA1c value for an interval preceding an interval corresponding to the eA1c value so as to provide an expected value for a laboratory HbA1c value at the same corresponding interval. |
| FILED | Monday, November 16, 2020 |
| APPL NO | 17/776717 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/14532 (20130101) Original (OR) Class Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/1723 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220395486 | AREA-GOMEZ et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Estela AREA-GOMEZ (New York, New York); Eric A. SCHON (Bronx, New York) |
| ABSTRACT | The invention provides for methods for treating Alzheimer's Disease in a subject by reducing ER-MAM localized APP-C99. |
| FILED | Friday, January 28, 2022 |
| APPL NO | 17/588104 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/11 (20130101) A61K 31/37 (20130101) A61K 31/40 (20130101) A61K 31/55 (20130101) A61K 31/137 (20130101) A61K 31/166 (20130101) A61K 31/192 (20130101) A61K 31/197 (20130101) A61K 31/327 (20130101) A61K 31/366 (20130101) A61K 31/397 (20130101) Original (OR) Class A61K 31/513 (20130101) A61K 31/519 (20130101) A61K 31/566 (20130101) A61K 31/675 (20130101) A61K 31/4188 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220395487 | Pyle et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anna Marie Pyle (Guilford, Connecticut); David Rawling (Salt Lake City, Utah); Erik G. Jagdmann (Holly Springs, North Carolina); Olga Potapova (Cheshire, Connecticut) |
| ABSTRACT | The present disclosure provides certain RIG-I antagonists. In certain embodiments, the antagonists of the disclosure can be used to treat or prevent a disease or disorder in a subject. |
| FILED | Wednesday, November 04, 2020 |
| APPL NO | 17/773889 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/403 (20130101) Original (OR) Class A61K 31/4184 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220395494 | ABRAMS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Health Research, Inc. (Buffalo, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Scott I. ABRAMS (Amherst, New York); Sean H. COLLIGAN (Buffalo, New York) |
| ABSTRACT | Provided are methods for treatment of cancer. The method comprises administering to an individual who has cancer a combination of treatment to reduce MDSC burden and immune therapy. For example, an individual may be administered brequinar and an immune checkpoint inhibitor. This disclosure provides a method for redirecting early myeloid precursors away from generating MDSCs thereby reducing MDSC burden. |
| FILED | Thursday, November 05, 2020 |
| APPL NO | 17/773838 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) Original (OR) Class A61K 31/4353 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20220395500 — SMALL MOLECULE ACTIVATORS OF INTERFERON REGULATORY FACTOR 3 AND METHODS OF USE THEREOF
| US 20220395500 | Stevens et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Neuralexo, Inc. (Portland, Oregon) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Susan Stevens (Portland, Oregon); Mary Stenzel-Poore (Portland, Oregon); Marie Foss (Portland, Oregon); Aaron Nilsen (Portland, Oregon); Haihong Jin (Portland, Oregon) |
| ABSTRACT | Small molecule activators of interferon regulatory factor (IRF), such as IRF3, and methods of use are provided. In particular, compositions and methods for upregulating interferon regulatory factor 3 (IRF3) activity, such as in the brain following stroke to provide potent protection against ischemic brain injury, to improve a therapeutic time window for providing treatments to stroke patients and/or for enhancement of vaccine platforms are disclosed. |
| FILED | Tuesday, May 04, 2021 |
| APPL NO | 17/307851 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 2017/22082 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) A61K 31/167 (20130101) A61K 31/341 (20130101) A61K 31/381 (20130101) A61K 31/423 (20130101) A61K 31/427 (20130101) A61K 31/428 (20130101) A61K 31/437 (20130101) A61K 31/496 (20130101) Original (OR) Class A61K 31/519 (20130101) A61K 31/4178 (20130101) A61K 31/4245 (20130101) A61K 31/4365 (20130101) A61K 31/4439 (20130101) A61K 31/5377 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220395511 | England et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Sarah England (St. Louis, Missouri); Manasi Malik (St. Louis, Missouri); Princess Imoukhuede (St. Louis, Missouri); Yingye Fang (St. Louis, Missouri) |
| ABSTRACT | Among the various aspects of the present disclosure is the provision of OXTR chaperones and methods of use thereof. An aspect of the present disclosure provides for a method of increasing the display of oxytocin receptor (OXTR) on a plasma membrane in a cell of a subject comprising: administering an OXTR chaperone, wherein the OXTR chaperone increases OXTR on a cell surface. Another aspect of the present disclosure provides for a method of increasing or restoring oxytocin sensitivity in a subject comprising: administering an OXTR chaperone, wherein the OXTR chaperone increases OXTR on a cell surface. Yet another aspect of the present disclosure provides for a method of increasing the efficacy of oxytocin or synthetic oxytocin in a subject comprising: administering an OXTR chaperone, wherein the OXTR chaperone increases OXTR on a cell surface. |
| FILED | Friday, June 10, 2022 |
| APPL NO | 17/837224 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) A61K 31/166 (20130101) A61K 31/4709 (20130101) A61K 31/5355 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220395563 | Nel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Andre E. Nel (Sherman Oaks, California); Tian Xia (Los Angeles, California); Qi Liu (Los Angeles, California) |
| ABSTRACT | In various embodiments tolerogenic nanoparticles are provided that induce immune tolerance to one or more desired antigen(s) and/or that reduce an immune response to those antigen(s). In certain embodiments the tolerogenic nanoparticle comprises a nanoparticle comprising a biocompatible polymer; an antigen disposed within or attached to said biocompatible polymer where said antigen comprises an antigen to which immune tolerance is to be induced by administration of said tolerogenic nanoparticle to a mammal; and a first targeting moiety that binds to a scavenger receptor in the liver, and/or a second targeting moiety that binds to a mannose receptor in the liver, and/or a third targeting moiety that binds to hepatocytes, wherein said first and/or second and/or third targeting moiety are attached to the surface of said nanoparticle. |
| FILED | Wednesday, November 11, 2020 |
| APPL NO | 17/775245 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/436 (20130101) A61K 39/001 (20130101) A61K 39/0008 (20130101) Original (OR) Class A61K 39/35 (20130101) A61K 2039/54 (20130101) A61K 2039/627 (20130101) A61K 2039/6031 (20130101) A61K 2039/6093 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/06 (20180101) A61P 37/08 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220395567 | Rice et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Peter A. Rice (Southborough, Massachusetts); Michael W. Pennington (Evans, Georgia) |
| ABSTRACT | In some aspects, the disclosure relates to compositions of peptide mimics useful in the treatment of Neisseria gonorrhoeae (N. gonorrhoeae). In some embodiments, the peptide mimics are multi-antigenic molecules of a conserved gonococcal lipoohgosaccharaide (LOS) epitope. In some aspects, the disclosure relates to methods of making peptide mimics for the treatment of N. gonorrhoeae. In some aspects, the disclosure relates to methods of using peptide mimics for the treatment of N. gonorrhoeae. |
| FILED | Tuesday, September 22, 2020 |
| APPL NO | 17/762159 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/095 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Peptides C07K 7/64 (20130101) C07K 14/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220395568 | YU et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Marshall University Research Corporation (Huntington, West Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hongwei D. YU (Huntington, West Virginia); Meagan E. VALENTINE (Huntington, West Virginia); Brandon D. KIRBY (Huntington, West Virginia); Richard M. NILES (Huntington, West Virginia) |
| ABSTRACT | Methods of treating a Pseudomonas bacterial infection and/or eliciting an immune response in a subject are provided and include administering to the subject a vaccine including a modified Pseudomonas bacterium missing or deficient in alpha-1,3-rhamnosyltransferase and/or one or more other virulence factors. Vaccines comprising a modified Pseudomonas bacterium missing or deficient in alpha-1,3-rhamnosyltransferase are further provided. |
| FILED | Friday, November 06, 2020 |
| APPL NO | 17/775468 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/104 (20130101) Original (OR) Class A61K 2039/522 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220395569 | Buck et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Christopher B. Buck (Bethesda, Maryland); Diana V. Pastrana (Arlington, Virginia) |
| ABSTRACT | Disclosed herein are methods of eliciting an immune response against a polyomavirus (for example, BKV serotype I (BKV-I), BKV serotype II (BKV-II), BKV serotype III (BKV-III) and/or BKV serotype IV (BKV-IV)) and methods of treating or inhibiting polyomavirus-associated pathology (such as polyomavirus-associated nephropathy, BKV-associated hemorrhagic cystitis, or JC virus-associated progressive multifocal leukoencephalopathy; PML). Further disclosed are immunogenic compositions of use in the disclosed methods. Also disclosed are methods of selecting an organ transplant donor and/or recipient including detecting whether the prospective donor and/or recipient has BKV serotype-specific (such as BKV serotype IV-specific) neutralizing antibodies. |
| FILED | Thursday, August 25, 2022 |
| APPL NO | 17/822345 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/5258 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/70 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220395577 | Tannous et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bakhos Tannous (Lynnfield, Massachusetts); Christian Badr (Malden, Massachusetts); Ralph Mazitschek (Belmont, Massachusetts); Neil Connor Payne (Madison, Connecticut) |
| ABSTRACT | The present application provides methods and compounds of modulating Nrf2 pathway. Methods for treating cancer and neurodegenerative conditions are also provided. |
| FILED | Friday, October 02, 2020 |
| APPL NO | 17/765667 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/55 (20170801) Original (OR) Class A61K 47/545 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 323/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220395583 | HOLT |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Jeffrey R. HOLT (Boston, Massachusetts) |
| ABSTRACT | The present invention features a dual vector system for disrupting and replacing a target gene comprising a mutation (e.g., dominant, recessive mutation). Embodiments of the invention may also provide compositions comprising the dual vector system, and methods of using the dual vector system, including but not limited to methods of modifying the genome of a cell, methods of genomic editing, and methods of treating cells or a subject suffering from a genetic disease comprising a mutation. |
| FILED | Thursday, July 02, 2020 |
| APPL NO | 17/624145 |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 2217/075 (20130101) A01K 2227/105 (20130101) A01K 2267/0306 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) Original (OR) Class A61K 48/0075 (20130101) Peptides C07K 14/705 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/86 (20130101) C12N 15/102 (20130101) C12N 2310/20 (20170501) C12N 2750/14143 (20130101) C12N 2800/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220395589 | Green et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jordan J. Green (Baltimore, Maryland); David Wilson (Baltimore, Maryland); Yuan Rui (Baltimore, Maryland) |
| ABSTRACT | Cationic polymers having one or more anionic ligand end groups, including a new class of carboxylated branched poly(beta-amino ester)s that can self-assemble into nanoparticles for efficient intracellular delivery of different biomolecules, including a variety of proteins is disclosed. |
| FILED | Monday, October 26, 2020 |
| APPL NO | 17/771142 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1647 (20130101) A61K 31/7088 (20130101) A61K 38/47 (20130101) A61K 38/164 (20130101) A61K 38/168 (20130101) A61K 38/465 (20130101) A61K 49/0093 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220395615 | Muschalek et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rachael Muschalek (College Station, Texas); Keith Hearon (Boston, Massachusetts); Landon D. Nash (Sunnyvale, California); Duncan J. Maitland (College Station, Texas) |
| ABSTRACT | An embodiment includes a system comprising: a substrate of a medical device; an un-foamed polyurethane coating directly contacting the substrate and fixedly attached to the substrate; a thermoset polyurethane shape memory polymer (SMP) foam, having first and second states, which directly contacts the polyurethane coating and fixedly attaches to the polyurethane coating; wherein the polyurethane coating fixedly attaches the SMP foam to the substrate. Other embodiments are described herein. |
| FILED | Thursday, June 23, 2022 |
| APPL NO | 17/847426 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 17/145 (20130101) A61L 27/34 (20130101) A61L 27/56 (20130101) A61L 31/10 (20130101) Original (OR) Class A61L 31/146 (20130101) A61L 2400/16 (20130101) A61L 2430/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220395686 | Tai |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh -Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Changfeng Tai (Wexford, Pennsylvania) |
| ABSTRACT | Provided herein is a method of blocking a nerve or neuron including applying an electrical stimulation to the nerve or neuron, wherein the electrical stimulation is of an intensity that is greater than an excitation threshold of the nerve or neuron for a length of time sufficient to produce a block of nerve conduction or neuron excitation. |
| FILED | Tuesday, June 30, 2020 |
| APPL NO | 17/624041 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0551 (20130101) A61N 1/36007 (20130101) Original (OR) Class A61N 1/36153 (20130101) A61N 1/36171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220395687 | Feng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | University of Connecticut (Farmington, Connecticut) |
| INVENTOR(S) | Bin Feng (Storrs, Connecticut); Longtu Chen (Coventry, Connecticut); Phillip P. Smith (Storrs, Connecticut) |
| ABSTRACT | Systems and methods are provided for electrical stimulation using electrical neurostimulators to treat neurological disorders. In exemplary implementations, the systems and methods effectuate selective sensory transmission block by spatially and temporally patterned multichannel, closed-loop electrical stimulation of neural tissue across the intervertebral foramina. The systems and methods optimize stimulation parameters according to the conduction velocity of afferents leading to effective neural transmission block. The systems and methods provide a dramatic improvement of selective transmission block, e.g., in a sub-population of unmyelinated C-fibers and slow-conducting Aδ fibers, by combining spatial, frequency and temporal parameters in the disclosed stimulation paradigm. An optimized start and termination of the stimulation may be implemented, as desired, thereby reducing overall energy consumption by reducing the stimulus strength during the maintenance phase of neural transmission block. |
| FILED | Wednesday, June 15, 2022 |
| APPL NO | 17/840869 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0551 (20130101) A61N 1/36057 (20130101) A61N 1/36071 (20130101) Original (OR) Class A61N 1/36139 (20130101) A61N 1/36171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396547 | ROY et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF KANSAS (Lawrence, Kansas); Oregon Health and Science University (Portland, Oregon) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sudeshna ROY (Lawrence, Kansas); Paolo BERNARDI (Padova, Italy); Michael FORTE (Portland, Oregon); Frank SCHOENEN (Lawrence, Kansas); Justina SILEIKYTE (Padova, Italy) |
| ABSTRACT | The present technology relates to compounds of any one of Formula I, II, IIa, III, IV, and/or V as described herein and their tautomers and/or pharmaceutically acceptable salts, compositions, and methods of uses thereof. |
| FILED | Monday, December 14, 2020 |
| APPL NO | 17/120607 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/42 (20130101) A61K 31/415 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) A61P 25/00 (20180101) Acyclic or Carbocyclic Compounds C07C 235/38 (20130101) C07C 235/42 (20130101) Original (OR) Class C07C 235/56 (20130101) Heterocyclic Compounds C07D 203/04 (20130101) C07D 211/14 (20130101) C07D 231/14 (20130101) C07D 261/18 (20130101) C07D 295/135 (20130101) C07D 295/185 (20130101) C07D 413/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396550 | Ghosh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Arun K. Ghosh (West Lafayette, Indiana); Monika Yadav (West Lafayette, Indiana); Andrew Mesecar (West Lafayette, Indiana) |
| ABSTRACT | Inhibitors of SARS-CoV-2 (COVID), pharmaceutical compositions comprising same; and methods of treating a severe acute respiratory syndrome. |
| FILED | Thursday, May 26, 2022 |
| APPL NO | 17/826061 |
| CURRENT CPC | Heterocyclic Compounds C07D 207/26 (20130101) Original (OR) Class C07D 227/087 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396551 | Messick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Troy E. Messick (Upper Darby, Pennsylvania); Garry R. Smith (Royersford, Pennsylvania); Allen B. Reitz (Lansdale, Pennsylvania); Paul M. Lieberman (Wynnewood, Pennsylvania); Mark E. McDonnell (Lansdale, Pennsylvania); Yan Zhang (Fort Washington, Pennsylvania); Venkata Velvadapu (Ankeny, Iowa) |
| ABSTRACT | Pharmaceutical compositions of the invention comprise EBNA1 inhibitors useful for the treatment of diseases caused by EBNA1 activity such as cancer, infectious mononucleosis, chronic fatigue syndrome, multiple sclerosis, systemic lupus erythematosus and rheumatoid arthritis. Pharmaceutical compositions of the invention also comprise EBNA1 inhibitors useful for the treatment of diseases caused by latent Epstein-Barr Virus (EBV) infection. Pharmaceutical compositions of the invention also comprise EBNA1 inhibitors useful for the treatment of diseases caused by lytic Epstein-Barr Virus (EBV) infection. |
| FILED | Wednesday, December 22, 2021 |
| APPL NO | 17/558877 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/192 (20130101) A61K 31/404 (20130101) A61K 31/496 (20130101) A61K 31/4439 (20130101) Acyclic or Carbocyclic Compounds C07C 53/18 (20130101) C07C 63/66 (20130101) C07C 65/19 (20130101) C07C 65/28 (20130101) C07C 211/27 (20130101) C07C 217/84 (20130101) C07C 229/56 (20130101) C07C 229/64 (20130101) C07C 233/11 (20130101) C07C 233/64 (20130101) C07C 233/65 (20130101) C07C 235/58 (20130101) C07C 255/54 (20130101) C07C 255/55 (20130101) C07C 311/08 (20130101) C07C 311/16 (20130101) C07C 311/17 (20130101) C07C 317/14 (20130101) C07C 317/44 (20130101) C07C 2601/02 (20170501) Heterocyclic Compounds C07D 207/08 (20130101) C07D 207/12 (20130101) C07D 207/14 (20130101) C07D 207/16 (20130101) C07D 207/327 (20130101) Original (OR) Class C07D 209/08 (20130101) C07D 211/70 (20130101) C07D 213/55 (20130101) C07D 213/64 (20130101) C07D 213/74 (20130101) C07D 215/14 (20130101) C07D 231/12 (20130101) C07D 235/06 (20130101) C07D 239/26 (20130101) C07D 249/06 (20130101) C07D 277/30 (20130101) C07D 295/155 (20130101) C07D 307/79 (20130101) C07D 333/54 (20130101) C07D 401/04 (20130101) C07D 401/10 (20130101) C07D 403/10 (20130101) C07D 409/10 (20130101) C07D 417/10 (20130101) C07D 471/04 (20130101) C07D 487/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396555 | Wrobel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Biohaven Therapeutics Ltd. (New Haven, Connecticut) |
| ASSIGNEE(S) | Biohaven Therapeutics Ltd. (New Haven, Connecticut) |
| INVENTOR(S) | Jay Edward Wrobel (Lawrenceville, New Jersey); Allen B. Reitz (Lansdale, Pennsylvania); Jeffery Claude Pelletier (Lafayette Hill, Pennsylvania); Garry Robert Smith (Royersford, Pennsylvania); Haiyan Bian (Princeton, New Jersey) |
| ABSTRACT | Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole. Prodrugs of riluzole have enhanced stability to hepatic metabolism and are delivered into systemic circulation by oral administration, and then cleaved to release riluzole in the plasma via either an enzymatic or general biophysical release process. |
| FILED | Monday, May 04, 2020 |
| APPL NO | 16/865498 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/2063 (20130101) Heterocyclic Compounds C07D 277/82 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396556 | Mitchell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Mitchell (Philadelphia, Pennsylvania); Margaret Billingsley (Hockessin, Delaware) |
| ABSTRACT | The present invention relates to lipids and compositions thereof. In various aspects of the invention, the compositions are lipid nanoparticle compositions used to deliver various nucleic acid molecules and/or therapeutic agents to selected targets, such as cells for gene delivery, and/or to prevent or treat diseases or disorders in a subject in need thereof. |
| FILED | Monday, October 19, 2020 |
| APPL NO | 17/769858 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1272 (20130101) A61K 39/0005 (20130101) Heterocyclic Compounds C07D 295/135 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396564 | Beaton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Epigen Biosciences, Inc. (San Diego, California) |
| ASSIGNEE(S) | Epigen Biosciences, Inc. (San Diego, California) |
| INVENTOR(S) | Graham Beaton (Vista, California); Fabio Tucci (San Diego, California); Satheesh Ravula (San Diego, California); Suk Joong Lee (San Diego, California); Chandravadan Shah (San Diego, California) |
| ABSTRACT | Pyrimidine and Pyridine containing compounds are described herein that are enzyme p70S6K inhibitors useful in the treatment of S6K-dependent or S6K-mediated diseases and conditions, including but not limited to cancer, fibrotic metabolic and certain neurological disorders. |
| FILED | Monday, May 31, 2021 |
| APPL NO | 17/334921 |
| CURRENT CPC | Heterocyclic Compounds C07D 401/04 (20130101) C07D 403/04 (20130101) Original (OR) Class C07D 405/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396572 | Thompson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Scott Thompson (Baltimore, Maryland); Adam Van Dyke (Baltimore, Maryland); Craig Thomas (Gaithersburg, Maryland); Patrick Morris (Laurel, Maryland) |
| ABSTRACT | The present invention relates to novel alpha5 subunit-selective negative allosteric modulators of GABAA receptors that have been deuterated to improve their medicinal properties by prolonging their half-lives, rendering them useful as fast-acting pharmaceutical treatments for depression related disorders. |
| FILED | Tuesday, August 09, 2022 |
| APPL NO | 17/883734 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/24 (20180101) Heterocyclic Compounds C07D 413/14 (20130101) C07D 417/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396597 | Covey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Douglas Covey (St. Louis, Missouri); Steven Mennerick (St. Louis, Missouri) |
| ABSTRACT | N-methyl-d-aspartate receptors (NMDAR) and/or potentiating y-aminobutyric acid receptors (GABAAR) agents and uses thereof are described. Uses of these agents include methods of treating or preventing various psychiatric diseases, disorders, or conditions and methods of treating or preventing alcohol use disorder in a subject in need thereof. |
| FILED | Friday, October 16, 2020 |
| APPL NO | 17/771718 |
| CURRENT CPC | Steroids C07J 1/0003 (20130101) C07J 13/007 (20130101) C07J 31/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396604 | Kadoch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Cigall Kadoch (Newton, Massachusetts); Alfredo M. Valencia (Santa Ana, California) |
| ABSTRACT | The present invention is directed to compositions comprising modified SMARCB1 and uses thereof. |
| FILED | Wednesday, October 21, 2020 |
| APPL NO | 17/770464 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 49/0004 (20130101) A61K 49/0056 (20130101) Peptides C07K 14/4702 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6875 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396606 | Smith et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sheena N. Smith (Urbana, Illinois); Daniel T. Harris (Urbana, Illinois); David M. Kranz (Urbana, Illinois) |
| ABSTRACT | T cell receptors (TCRs) that have higher affinity for the Survivin antigen are provided. The high affinity TCRs were engineered through the generation of mutational libraries of TCRs in a single-chain format, followed by selection for improved stability and affinity on the surface of yeast (i.e. directed evolution). In embodiments, the engineered TCRs can be used in soluble form for targeted delivery in vivo, or as genes introduced into T cells in an adoptive T cell setting. |
| FILED | Thursday, January 27, 2022 |
| APPL NO | 17/586652 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/4747 (20130101) C07K 14/7051 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396618 | XU et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Foundation for The State University of NewYork (Amherst, New York); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ding XU (East Amherst, New York); Jeffrey ESKO (La Jolla, California); Miaomiao LI (Tonawanda, New York) |
| ABSTRACT | Provided are antibodies specific for the heparan sulfate binding site of Receptor for Advanced Glycation Endproducts (RAGE). Also provided are methods for treating of conditions in which RAGE is involved comprising administration of the antibodies to an individual in need of treatment. |
| FILED | Monday, November 02, 2020 |
| APPL NO | 17/772853 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6811 (20170801) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/16 (20180101) A61P 19/10 (20180101) A61P 35/00 (20180101) Peptides C07K 16/2803 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396621 | KIM et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chanhyuk KIM (Daejeon, South Korea); Jun Y. AXUP (San Diego, California); Hwayoung YUN (Daejeon, South Korea); Peter G. SCHULTZ (La Jolla, California); Jennifer MA (La Jolla, California); Jiayin SHEN (San Diego, California); Pengyu YANG (San Diego, California) |
| ABSTRACT | Methods, compositions and uses are provided for bispecific antibodies comprising one or more unnatural amino acids. The bispecific antibodies may bind to two or more different receptors, coreceptors, antigens, or cell markers on one or more cells. The bispecific antibodies may be used to treat a disease or condition (e.g., cancer, autoimmune disease, pathogenic infection, inflammatory disease). The bispecific antibodies may be used to modulate (e.g., stimulate or suppress) an immune response. |
| FILED | Wednesday, June 22, 2022 |
| APPL NO | 17/847054 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/3955 (20130101) A61K 39/39558 (20130101) A61K 47/542 (20170801) A61K 2039/505 (20130101) Acyclic or Carbocyclic Compounds C07C 275/16 (20130101) C07C 275/24 (20130101) Heterocyclic Compounds C07D 249/04 (20130101) Peptides C07K 16/32 (20130101) C07K 16/468 (20130101) C07K 16/2803 (20130101) C07K 16/2806 (20130101) C07K 16/2809 (20130101) Original (OR) Class C07K 16/2851 (20130101) C07K 16/2863 (20130101) C07K 16/2887 (20130101) C07K 16/2896 (20130101) C07K 16/3069 (20130101) C07K 2317/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396704 | Akilavasan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Agienic Inc. (Tucson, Arizona) |
| ASSIGNEE(S) | Agienic Inc. (Tucson, Arizona) |
| INVENTOR(S) | Jeganathan Akilavasan (Tucson, Arizona); Kyler Novotony (Tucson, Arizona); Anoop Agrawal (Tucson, Arizona); Donald R. Uhlmann (Tucson, Arizona) |
| ABSTRACT | Aqueous formulations containing antimicrobial materials dispersed in solutions or emulsions, methods of their preparation, application of such compositions to surfaces, and their resulting coatings. Coating of hydrophobic surfaces with aqueous solutions or suspensions containing antimicrobial materials are disclosed. Several applications of the antimicrobial coatings are described including the coating of solid and porous substrates such as fabrics which may be used for gowns, masks, and other personal protection equipment. |
| FILED | Friday, July 01, 2022 |
| APPL NO | 17/855951 |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 13/1192 (20130101) A41D 13/1209 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 1/00 (20130101) Original (OR) Class C09D 5/14 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 11/13 (20130101) D06M 2101/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396758 | NIVALA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeffrey M. NIVALA (Santa Cruz, California); Douglas B. MARKS (Santa Cruz, California); Mark A. AKESON (Santa Cruz, California) |
| ABSTRACT | Described herein is a device and method for translocating a protein through a nanopore and monitoring electronic changes caused by different amino acids in the protein. The device comprises a nanopore in a membrane, an amplifier for providing a voltage between the cis side and trans side of the membrane, and an NTP driven unfoldase which processed the protein to be trans-located. The exemplified unfoldase is the ClpX unfoldase from E. coli. |
| FILED | Monday, May 16, 2022 |
| APPL NO | 17/745399 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Apparatus for Enzymology or Microbiology; C12M 47/06 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/48 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54366 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396772 | Nishimune et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Kansas (Lawrence, Kansas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hiroshi Nishimune (Kansas City, Missouri); Richard Barohn (Kansas City, Missouri); Buddhadeb Dawn (Las Vegas, Nevada); Yomna Badawi (Leawood, Kansas); James W. Mitchell (Overland Park, Kansas); Rupal Soder (Prairie Village, Kansas) |
| ABSTRACT | Embodiments of the present disclosure relate generally to the production of therapeutic mesenchymal stem cells (MSCs). More particularly, the present disclosure relates to the use of cell culture compositions and methods for generating MSCs that secrete neurotrophic factors and synaptic organizing agents for the treatment of neurodegenerative diseases such as Amyotrophic Lateral Sclerosis (ALS). As such, the present disclosure addresses the need for establishing a reliable source of therapeutic stem cells useful for the treatment of neurodegenerative diseases. |
| FILED | Monday, January 24, 2022 |
| APPL NO | 17/582704 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/51 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0668 (20130101) Original (OR) Class C12N 2500/32 (20130101) C12N 2501/10 (20130101) C12N 2501/13 (20130101) C12N 2501/105 (20130101) C12N 2501/115 (20130101) C12N 2501/135 (20130101) C12N 2501/165 (20130101) C12N 2533/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396777 | Shalek et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexander K. Shalek (Cambridge, Massachusetts); Peter Winter (Cambridge, Massachusetts); Andrew Navia (Cambridge, Massachusetts); Srivatsan Raghavan (Boston, Massachusetts); William Hahn (Boston, Massachusetts); Andrew Aguirre (Boston, Massachusetts); Brian Wolpin (Boston, Massachusetts); Jennyfer Galvez-Reyes (Cambridge, Massachusetts) |
| ABSTRACT | In certain example embodiments, the invention provides a method of generating an ex vivo cell-based system comprising dissociating an original tissue sample obtained from a subject into a single cell population; determining an in vivo phenotype of the tissue sample by conducting single-cell RNA analysis on a first portion of the single cells; establishing an ex vivo cell-based system from a second portion of the single cells; and culturing the ex vivo cell-based system in a medium or conditions selected to maintain the in vivo phenotype. In some embodiments, the original tissue sample is a tumor tissue sample, such as a pancreatic ductal adenocarcinoma (PDAC) tumor sample. |
| FILED | Monday, October 26, 2020 |
| APPL NO | 17/770463 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0693 (20130101) Original (OR) Class C12N 2501/24 (20130101) C12N 2501/415 (20130101) C12N 2502/1323 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396833 | Askary et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Amjad Askary (Pasadena, California); Michael B. Elowitz (Los Angeles, California); Mark W. Budde (Arcadia, California); Carlos Lois (South Pasadena, California); Luis Sanchez Guardado (Pasadena, California); Long Cai (Pasadena, California); James Linton (Pasadena, California) |
| ABSTRACT | Disclosed herein include systems, methods, compositions, and kits for in situ readout of barcodes, such as DNA barcodes. Barcode constructs containing a promoter (e.g., a phage promoter) that is inactive in live cells can be integrated in the genomes of cells. Cells can be fixed, and phage RNA polymerase can be used for transcription of the barcode to RNA transcripts. The RNA transcripts can be detected using, for example, fluorescent imaging and used to determine barcode sequences. |
| FILED | Thursday, August 04, 2022 |
| APPL NO | 17/817516 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6818 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 1/6876 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396835 | Weitz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David A. Weitz (Cambridge, Massachusetts); Jeremy Agresti (Cambridge, Massachusetts) |
| ABSTRACT | The present invention is generally related to systems and methods for producing a plurality of droplets. The droplets may contain varying species, e.g., for use as a library. In some cases, the fluidic droplets may be rigidified to form rigidified droplets (e.g., gel droplets). In certain embodiments, the droplets may undergo a phase change (e.g., from rigidified droplets to fluidized droplets), as discussed more herein. In some cases, a species may be added internally to a droplet by exposing the droplet to a fluid comprising a plurality of species. |
| FILED | Friday, June 24, 2022 |
| APPL NO | 17/848909 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/04 (20130101) B01J 19/0046 (20130101) B01J 2219/00599 (20130101) B01J 2219/00709 (20130101) B01J 2219/00711 (20130101) B01J 2219/00716 (20130101) B01J 2219/00722 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) C12Q 1/6876 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220397530 | Boppart et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen Boppart (Champaign, Illinois); Janet Sorrells (Champaign, Illinois); Rishyashring Raman Iyer (Champaign, Illinois) |
| ABSTRACT | A photon peak event detection system accepts an analog output from a photon sensor, directly digitizes the analogy output and includes a graphics processing unit (GPU) programmed to conduct a photon peak event detection in real-time via a photon count program that analyzes the digitized photon sensor output in sampling periods each having at least three consecutive data points to determine a local maximum among the consecutive data points and compare the local maximum to one or more predetermined thresholds to determine whether or not a photon was received in each sampling period, the algorithm providing photon counts to a phasor analysis program in the GPU. The phasor analysis program calculates pixelwise fluorescence lifetime phasor data in real-time and sends the data to a central processing unit. |
| FILED | Thursday, June 09, 2022 |
| APPL NO | 17/836146 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6402 (20130101) G01N 21/6408 (20130101) G01N 21/6458 (20130101) Original (OR) Class G01N 2201/06113 (20130101) Optical Elements, Systems, or Apparatus G02B 21/16 (20130101) Image Data Processing or Generation, in General G06T 1/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220397533 | Cheng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Quan Jason Cheng (Irvine, California); Alexander Scott Lambert (San Gabriel, California); Santino Nicholas Valiulis (Los Angeles, California); Alexander Scott Malinick (Chino Hills, California); Ichiro Tanabe (Osaka, Japan); Bochao Li (Riverside, California) |
| ABSTRACT | A thin aluminum film substrate and microarrays thereof including a substrate and a thin film of aluminum deposited on the substrate for surface plasmon resonance analysis. Methods of forming the thin aluminum film substrate and microarrays including providing a substrate, using electron-beam physical vapor deposition (EBPVD) to deposit a thin film of Al on a surface of the substrate. Also disclosed are methods of detecting an analyte, wherein a functionalized surface of the thin aluminum film includes a biomolecule and the methods include applying a sample including the analyte to the thin aluminum film substrate, and using surface plasmon resonance (SPR) spectroscopy to detect molecular interactions between the biomolecule and the analyte at a surface of the thin aluminum film substrate. In some examples, an unmodified Al film with an Al2O3 layer is effective in enriching phosphorylated peptides. In some examples, a coating of an ionic polymer is used to analyze charged-based interactions of biomolecules. |
| FILED | Wednesday, June 08, 2022 |
| APPL NO | 17/805971 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/18 (20130101) C23C 14/30 (20130101) C23C 14/5853 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 49/164 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220397564 | Ma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Zhen Ma (Jamesville, New York); Plansky Hoang (Syracuse, New York) |
| ASSIGNEE(S) | SYRACUSE UNIVERSITY (SYRACUSE, New York) |
| INVENTOR(S) | Zhen Ma (Jamesville, New York); Plansky Hoang (Syracuse, New York) |
| ABSTRACT | A developmental toxicity screening assay using spatially organized cardiac organoids with contracting cardiomyocytes in the center surrounded by stromal cells distributed along the pattern perimeter engineered from human induced pluripotent stem cells (hiPSCs). Cardiac organoids generated from 600 μm-diameter circles were used as a developmental toxicity screening assay for the quantification of the embryotoxic potential of nine pharmaceutical compounds. The cardiac organoids were demonstrated as having a potential use as an in vitro platform for studying organoid structure-function relationships, developmental processes, and drug-induced cardiac developmental toxicity. |
| FILED | Friday, June 10, 2022 |
| APPL NO | 17/837697 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0657 (20130101) C12N 2506/45 (20130101) C12N 2535/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5014 (20130101) Original (OR) Class G01N 33/5044 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220397567 | MARX et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York); THE NEW YORK AND PRESBYTERIAN HOSPITAL (New York, New York); HARVARD UNIVERSITY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven O. MARX (New york, New York); Alexander KUSHNIR (New York, New York); Sergey ZAKHAROV (New York, New York); Alexander KATCHMAN (New York, New York); Steven P. GYGI (New York, New York); Marian KALOCSAY (New York, New York); Manu BEN-JOHNY (New York, New York); Henry M. COLECRAFT (New York, New York); Guoxia LIU (New York, New York) |
| ABSTRACT | The method for increasing contractility in patients with systolic heart failure involves screening for candidate small molecules which block the interaction between Rad and the plasma membrane and/or block the interaction between Rad and the CaV1.2/CaVβ2 complex, or between Rad and CaVβ2, in order to increase cardiac contractility. A method for preventing calcium overload and arrhythmias in heart disease involves preventing the dissociation of Rad and the CaV1.2/CaVβ2 complex, or between Rad and CaVβ2, during beta-adrenergic system activation. Additionally, a method of screening for drugs that block interaction between an RGK GTPase protein and a β-subunit of the calcium channel is provided. A suitable technique, such as fluorescence resonance energy transfer (FRET), may be used to assess blocking of the interaction between the RGK GTPase protein and the β-subunit of the calcium channel for the treatment of heart disease, pain, diabetes, skeletal muscle disorders and/or central nervous system (CNS) disorders. |
| FILED | Thursday, July 02, 2020 |
| APPL NO | 17/624497 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5041 (20130101) G01N 33/5044 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220397568 | VILLANI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alexandra-chloe VIKKIANI (Boston, Massachusetts); Rahul SATIJA (New York, New York); Aviv REGEV (Cambridge, Massachusetts); Nir HACOHEN (Brookline, Massachusetts); The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexandra-Chloé VILLANI (Boston, Massachusetts); Rahul SATIJA (Cambridge, Massachusetts); Aviv Regev (Cambridge, Massachusetts); Nir HACOHEN (Boston, Massachusetts) |
| ABSTRACT | The present invention provides isolated immune cells, immune cell populations and compositions, as well as markers, marker signatures and molecular targets characterising the immune cells. The cell products, substances, compositions, markers, marker signatures, molecular targets, kits of parts and methods of the present invention provide for new ways to characterise, evaluate and modulate the immune system and immune responses. |
| FILED | Thursday, August 17, 2017 |
| APPL NO | 16/325807 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0634 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5047 (20130101) Original (OR) Class G01N 33/6893 (20130101) G01N 2800/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220397569 | Lutty et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gerard Lutty (Hyattsville, Maryland); Shuntaro Ogura (Baltimore, Maryland) |
| ABSTRACT | The present invention relates to the field of ophthalmology. More specifically, the present invention provides compositions and methods useful for screening for drugs to treat age-related macular degeneration (AMD) including geographic atrophy (GA). In one embodiment, a method comprises the steps of (a) administering a drug to a mammal, wherein the mammal comprises a rat or a mouse; (b) enucleating the eyes of the mammal; (c) removing the anterior eye and excising the retina from the eye, wherein the eye comprises an eyecup that comprises choroidal mast cells (MCs); and (d) measuring mast cell degranulation. In an alternative embodiment, a method of the present invention can comprise the steps of (a) contacting an eyecup of a mammal with a drug, wherein the eyecup comprises choroidal mast cells; and (b) measuring MC degranulation. |
| FILED | Friday, October 16, 2020 |
| APPL NO | 17/769960 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/563 (20130101) G01N 33/5047 (20130101) Original (OR) Class G01N 2333/918 (20130101) G01N 2333/4727 (20130101) G01N 2800/164 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220397578 | Slavov |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nikolai Slavov (Cambridge, Massachusetts) |
| ABSTRACT | The present invention generally provides, in various embodiments, improved methods of analyzing proteins utilizing liquid chromatography and tandem mass spectroscopy (LC-MS/MS), such as by multiplexing samples and using data-independent acquisition. |
| FILED | Friday, June 10, 2022 |
| APPL NO | 17/806468 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6842 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 49/0045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220397579 | Kanjananimmanont et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MESO SCALE TECHNOLOGIES, LLC. (Rockville, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sunsanee Kanjananimmanont (Germantown, Maryland); Sudeep Kumar (Basking Ridge, New Jersey); Navaratnam Manjula (Rockville, Maryland); Simone Barbero (Gaithersburg, Maryland); Martin Stengelin (Gaithersburg, Maryland); George Sigal (Rockville, Maryland) |
| ABSTRACT | The invention relates to methods and kits for quantitating radiation exposure in a subject exposed to radiation, at risk of exposure to radiation or suspected of having been exposed to radiation. In embodiments, the present disclosure provides multiplexed immunoassays for quantifying amounts of biomarkers for assessing radiation exposure in a sample. Also provided herein are kits for performing the multiplexed assays. |
| FILED | Wednesday, November 04, 2020 |
| APPL NO | 17/773896 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) Original (OR) Class G01N 33/54306 (20130101) G01N 2800/40 (20130101) G01N 2800/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220397621 | Tang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xueyan Tang (Minneapolis, Minnesota); Michael Garwood (Minneapolis, Minnesota); Steven Suddarth (Minneapolis, Minnesota) |
| ABSTRACT | Spin resonance spectroscopy and/or imaging is achieved using a system that combines longitudinal (e.g., along the z-axis) detection with a modulated fictitious field generated by a transverse plane (e.g., xy-plane) RF field. Based on z-axis detection of magnetization polarized by this fictitious field as it is modulated (e.g., modulated on and off, or otherwise), spin resonance signals (e.g., EPR, NMR) are measurable with high isolation simultaneous transmit and receive capability. Additionally or alternatively, spin relaxation times can be measured using the described systems. |
| FILED | Tuesday, March 08, 2022 |
| APPL NO | 17/689794 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/46 (20130101) Original (OR) Class G01R 33/60 (20130101) G01R 33/385 (20130101) G01R 33/34092 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220398873 | CANOVA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Marcello CANOVA (Columbus, Ohio); Shreshta RAJAKUMAR DESHPANDE (Columbus, Ohio); Shobhit GUPTA (Columbus, Ohio); Abhishek GUPTA (Columbus, Ohio) |
| ABSTRACT | The use of multiple horizon optimization for vehicle dynamics and powertrain control of a vehicle is provided. Long horizon optimization for a trip of the vehicle is performed, and an optimal value function is determined. Data is received from powertrain and/or connectivity features from one or more of components of the vehicle. Short horizon optimization for the trip is performed using a rollout algorithm, the optimal value function, and the received data. The operation of the vehicle is adjusted using results of the short horizon optimization. |
| FILED | Friday, November 06, 2020 |
| APPL NO | 17/774677 |
| CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 40/105 (20130101) B60W 2510/10 (20130101) Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere G07C 5/02 (20130101) G07C 5/008 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20220395033 | Stevenson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | IONA Tech (Telluride, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daan Stevenson (Telluride, Colorado); Jonathan Tapson (Telluride, Colorado) |
| ABSTRACT | A wireless anti-static device is disclosed, including an electronic sensing circuit that measures the polarity and electrostatic potential of the subject relative to its surroundings. Ion guns of positive and negative polarities are able to transfer an arbitrary quantity and polarity of charge from the subject by ejecting ionized air molecules into the surrounding environment. A control unit is programmed to trigger the appropriate ion gun when a corresponding charge is measured on the body, in order to continually maintain the net charge on the body below a desired threshold. The subject is thus effectively grounded relative to its environment without requiring physical tethers to ground. |
| FILED | Friday, August 13, 2021 |
| APPL NO | 17/637196 |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 1/002 (20130101) A41D 13/008 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220395592 | HARRIS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | AquiSense Technologies LLC (Erlanger, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | THEODORE ROBERT HARRIS (CHARLOTTE, North Carolina); JENNIFER GODWIN PAGAN (CHARLOTTE, North Carolina); PAOLO BATONI (CHARLOTTE, North Carolina); JOHN ROBERT KRAUSE (CHARLOTTE, North Carolina) |
| ABSTRACT | An irradiation apparatus configured to be coupled to an irradiation chamber containing a material to be irradiated, comprising: a support structure; one or more radiation sources coupled to the support structure; and a heat exchange mechanism thermally coupled to the one or more radiation sources. The heat exchange mechanism comprises one or more of a thermoelectric cooling device, a vapor chamber, a heatsink, a heat dissipation structure, a fan, and a cooling coating. The one or more radiation sources comprise one or more UV radiation sources, one or more UV-C radiation. sources, one or more visible radiation sources, or a combination thereof. Optionally, the one or more radiation sources comprise a plurality of radiation sources arranged. in an array, Optionally, the one or more radiation sources deliver a combination of wavelengths to the material to be irradiated. |
| FILED | Monday, May 23, 2022 |
| APPL NO | 17/750791 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/10 (20130101) A61L 2/16 (20130101) A61L 2/084 (20130101) Original (OR) Class A61L 9/20 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/325 (20130101) C02F 2305/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220395898 | Hopkins et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey); Heavy Metal LLC (Fremont, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Adam Bayne Hopkins (San Jose, California); Salvatore TORQUATO (Princeton, New Jersey) |
| ABSTRACT | The present invention relates to granular composite density enhancement, and related methods and compositions. The applications where these properties are valuable include but are not limited to: 1) additive manufacturing (“3D printing”) involving metallic, ceramic, cermet, polymer, plastic, or other dry or solvent-suspended powders or gels, 2) concrete materials, 3) solid propellant materials, 4) cermet materials, 5) granular armors, 6) glass-metal and glass-plastic mixtures, and 7) ceramics comprising (or manufactured using) granular composites. |
| FILED | Wednesday, June 22, 2022 |
| APPL NO | 17/846300 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/052 (20220101) Original (OR) Class B22F 1/065 (20220101) B22F 3/11 (20130101) B22F 7/002 (20130101) B22F 7/02 (20130101) B22F 7/008 (20130101) B22F 10/20 (20210101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/342 (20151001) B23K 26/354 (20151001) Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 1/001 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 45/0001 (20130101) B29C 64/153 (20170801) B29C 64/165 (20170801) B29C 64/371 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 70/00 (20141201) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 3/04 (20130101) C03C 12/00 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 20/0096 (20130101) C04B 28/02 (20130101) C04B 35/56 (20130101) C04B 35/111 (20130101) C04B 35/547 (20130101) C04B 35/5626 (20130101) C04B 35/62695 (20130101) Alloys C22C 14/00 (20130101) C22C 32/0052 (20130101) C22C 38/002 (20130101) C22C 38/02 (20130101) C22C 38/44 (20130101) C22C 38/56 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396043 | JETHMALANI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Novol, Inc. (San Leandro, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jagdish JETHMALANI (San Leandro, California); Sanjiban CHAKRABORTY (San Leandro, California); Monica BHATIA (San Leandro, California) |
| ABSTRACT | Provided herein are methods of molding thermoplastic polymers into optical elements. The optical elements in the form of cylindrical discs, semi-finished lens blanks or finished lenses are compression molded at high temperature typically above thermoplastic polymers softening temperature and under high pressure. The semi-finished lens blanks and finished lenses are molded using front and back glass molds inside a mold assembly which reshapes the cylindrical discs that are either previously molded or cut out from thick slab. Also provided are methods for producing single vision and progressive addition lens prescriptions. |
| FILED | Monday, August 22, 2022 |
| APPL NO | 17/893017 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 51/30 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/0049 (20130101) Original (OR) Class B29D 11/00413 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2033/12 (20130101) Optical Elements, Systems, or Apparatus G02B 1/041 (20130101) Spectacles; Sunglasses or Goggles Insofar as They Have the Same Features as Spectacles; Contact Lenses G02C 7/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396484 | Wiesner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CORNELL UNIVERSITY (lthaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ulrich B. Wiesner (Ithaca, New York); Sarah A. Hesse (Redwood City, California); Kevin E. Fritz (Flemington, New Jersey); Peter A. Beaucage (Germantown, Maryland); Jin Suntivich (Ithaca, New York) |
| ABSTRACT | Asymmetric porous films, methods of making, and devices. An asymmetric porous film may have a surface layer, which may be an isoporous surface layer, disposed on a substructure, which may be a graded porous substructure that may have mesopores throughout. An asymmetric porous film may be a hybrid asymmetric porous film comprising one or more precursor(s). An asymmetric porous film may include one or more carbon material(s), one or more metalloid oxide(s), one or more metal(s), one or more metal oxide(s), one or more metal nitride(s), one or more metal oxynitride(s), one or more metal carbide(s), one or more metal carbonitrides, or a combination thereof. A method of making an asymmetric porous film may comprise formation of an asymmetric porous film using CA a mixture comprising a multiblock copolymer that can self-assemble and one or more precursor(s). |
| FILED | Tuesday, November 03, 2020 |
| APPL NO | 17/772542 |
| CURRENT CPC | Separation B01D 71/021 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/05 (20170801) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2006/16 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/583 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396487 | JOO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CORNELL UIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yong Lak JOO (Ithaca, New York); Mohammed ALAMER (Ithaca, New York) |
| ABSTRACT | Provided herein are high throughput continuous or semi-continuous reactors and processes for manufacturing expanded graphite materials. Such processes are suitable for manufacturing expanded graphite materials with little batch-to-batch variation. |
| FILED | Thursday, June 25, 2020 |
| APPL NO | 17/621833 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/28 (20130101) B01J 19/1887 (20130101) B01J 2219/00029 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/225 (20170801) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/82 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396789 | Banal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James L. Banal (Cambridge, Massachusetts); Mark Bathe (Cambridge, Massachusetts); Joseph Berleant (Cambridge, Massachusetts); Charles E. Leiserson (Cambridge, Massachusetts); Tao Benjamin Schardl (Cambridge, Massachusetts) |
| ABSTRACT | Disclosed are compositions and methods relating to sequence-controlled storage objected. The disclosed sequence-controlled storage objects can include (a) one or more different sequence-controlled polymers, and (b) a plurality of different feature tags. The sequence-controlled storage object can include (a) one or more different sequence-controlled polymers, and (b) a plurality of different digit tags. Also disclosed are methods of storing desired sequence-controlled polymers as a sequence-controlled storage object, comprising assembling a sequence-controlled storage object from (i) one or more different sequence-controlled polymers, (ii) a plurality of different feature tags, and (iii) optionally one or more encapsulating agents. Also disclosed are methods of automating the assembly of a sequence-controlled storage object comprising using a device with flow. |
| FILED | Thursday, June 09, 2022 |
| APPL NO | 17/836726 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) Original (OR) Class C12N 15/1089 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396811 | Fedorov |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrei Fedorov (Atlanta, Georgia) |
| ABSTRACT | The present disclosure provides for methods of delivering cargo material to a cell(s) in vivo or in vitro, devices configured to deliver cargo material to the cell, systems configured to deliver cargo material to the cell, and the like. The present disclosure can synergistically combine multiple technologies to improve the rate of cargo material introduction and utility of physical cellular modification in a transformative way compared to the current microinjection state-of-the art. |
| FILED | Monday, November 23, 2020 |
| APPL NO | 17/756088 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 5/00 (20130101) B01L 2400/0442 (20130101) Apparatus for Enzymology or Microbiology; C12M 35/02 (20130101) C12M 35/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/895 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396812 | Doudna et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jennifer A. Doudna (Berkeley, California); Jillian F. Banfield (Berkeley, California); David Burstein (Berkeley, California); Lucas Benjamin Harrington (Berkeley, California) |
| ABSTRACT | The present disclosure provides CasY proteins, nucleic acids encoding the CasY proteins, and modified host cells comprising the CasY proteins and/or nucleic acids encoding same. CasY proteins are useful in a variety of applications, which are provided. The present disclosure provides CasY guide RNAs that bind to and provide sequence specificity to the CasY proteins, nucleic acids encoding the CasY guide RNAs, and modified host cells comprising the CasY guide RNAs and/or nucleic acids encoding same. CasY guide RNAs are useful in a variety of applications, which are provided. The present disclosure provides methods of identifying a CRISPR RNA-guided endonuclease. |
| FILED | Thursday, May 19, 2022 |
| APPL NO | 17/749017 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/46 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/113 (20130101) C12N 15/902 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2740/16043 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396835 | Weitz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David A. Weitz (Cambridge, Massachusetts); Jeremy Agresti (Cambridge, Massachusetts) |
| ABSTRACT | The present invention is generally related to systems and methods for producing a plurality of droplets. The droplets may contain varying species, e.g., for use as a library. In some cases, the fluidic droplets may be rigidified to form rigidified droplets (e.g., gel droplets). In certain embodiments, the droplets may undergo a phase change (e.g., from rigidified droplets to fluidized droplets), as discussed more herein. In some cases, a species may be added internally to a droplet by exposing the droplet to a fluid comprising a plurality of species. |
| FILED | Friday, June 24, 2022 |
| APPL NO | 17/848909 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/04 (20130101) B01J 19/0046 (20130101) B01J 2219/00599 (20130101) B01J 2219/00709 (20130101) B01J 2219/00711 (20130101) B01J 2219/00716 (20130101) B01J 2219/00722 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) C12Q 1/6876 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396887 | Dinca et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mircea Dinca (Belmont, Massachusetts); Ruperto Mariano (Somerville, Massachusetts) |
| ABSTRACT | An electrode with a gas diffusion electrode (GDE) layer and a metal-organic framework (MOF) layer. The electrode overcomes mass transport limits by providing a gas diffusion pathway to conductive MOF electrodes. At the same applied potential, this translates to a tenfold improvement in current density (greater than 100 mA cm−2) relative to conventional conductive MOF electrode geometries (less than 1 mA cm−2). |
| FILED | Tuesday, May 31, 2022 |
| APPL NO | 17/828646 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/30 (20130101) C25B 11/032 (20210101) Original (OR) Class C25B 11/048 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220397528 | Kurabayashi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Katsuo Kurabayashi (Ann Arbor, Michigan); Muneesh Tewari (Ann Arbor, Michigan); Sung Won Choi (Ann Arbor, Michigan); Yujing Song (Ann Arbor, Michigan); Shiuan-Haur Su (Ann Arbor, Michigan) |
| ABSTRACT | The present disclosure provides methods, systems, and kits for detecting molecules in a sample with a pre-equilibrium digital immunoassay. The methods and systems provide means for quantifying molecules in a biological sample of minimal volume in short amounts of time. |
| FILED | Friday, November 13, 2020 |
| APPL NO | 17/776131 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/0612 (20130101) G01N 21/6428 (20130101) Original (OR) Class G01N 21/6452 (20130101) G01N 33/557 (20130101) G01N 2015/0065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220397530 | Boppart et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen Boppart (Champaign, Illinois); Janet Sorrells (Champaign, Illinois); Rishyashring Raman Iyer (Champaign, Illinois) |
| ABSTRACT | A photon peak event detection system accepts an analog output from a photon sensor, directly digitizes the analogy output and includes a graphics processing unit (GPU) programmed to conduct a photon peak event detection in real-time via a photon count program that analyzes the digitized photon sensor output in sampling periods each having at least three consecutive data points to determine a local maximum among the consecutive data points and compare the local maximum to one or more predetermined thresholds to determine whether or not a photon was received in each sampling period, the algorithm providing photon counts to a phasor analysis program in the GPU. The phasor analysis program calculates pixelwise fluorescence lifetime phasor data in real-time and sends the data to a central processing unit. |
| FILED | Thursday, June 09, 2022 |
| APPL NO | 17/836146 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6402 (20130101) G01N 21/6408 (20130101) G01N 21/6458 (20130101) Original (OR) Class G01N 2201/06113 (20130101) Optical Elements, Systems, or Apparatus G02B 21/16 (20130101) Image Data Processing or Generation, in General G06T 1/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220397531 | ANGEL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF SOUTH CAROLINA (COLUMBIA, South Carolina); LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (LIVERMORE, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | STANLEY MICHAEL ANGEL (COLUMBIA, South Carolina); JERRY CHANCE CARTER (LIVERMORE, California) |
| ABSTRACT | A hyperspectral imaging apparatus based on a monolithic or free space optical spatial heterodyne spectrometer (SHS) design, array detector, electromagnetic radiation source, and optical collection element is described. The apparatus enables the simultaneous acquisition of spatially isolated Fizeau fringe patterns, each having an encoded light product that is decoded to produce a spectral fingerprint of the interrogated object. Features specific to the SHS, such as a large entrance aperture, large acceptance angle, and no moving parts, enable a variety of optical collection schemes including lens arrays, solid-core and hollow core waveguides, and others. In one example, a microlens array (MLA) is configured with the hyperspectral imaging apparatus to simultaneously image many hundred spatially isolated Fizeau fringe patterns while interrogating an object using an electromagnetic radiation source. Each Fizeau fringe pattern recorded by the array detector is decoded to produce a full Raman or laser-induced breakdown spectroscopy (LIBS) spectrum. Compared to prior art, the hyperspectral imaging apparatus overcomes the primary limitations of needing to trade time resolution for both spectral and spatial data density because the imaging apparatus simultaneously acquires both spectral and special information. Based on the selection and configuration of diffraction gratings, the grating aperture size, Littrow wavelength (i.e., heterodyne wavelength), and optical collection configuration, the apparatus can be tailored to produced low or high spectral resolution with a spectral bandpass that covers a portion or the entire Raman spectral range (up to 4200 cm−1) and for LIBS as well. |
| FILED | Monday, November 11, 2019 |
| APPL NO | 17/772265 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) Original (OR) Class G01N 2201/0633 (20130101) G01N 2201/0635 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220397533 | Cheng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Quan Jason Cheng (Irvine, California); Alexander Scott Lambert (San Gabriel, California); Santino Nicholas Valiulis (Los Angeles, California); Alexander Scott Malinick (Chino Hills, California); Ichiro Tanabe (Osaka, Japan); Bochao Li (Riverside, California) |
| ABSTRACT | A thin aluminum film substrate and microarrays thereof including a substrate and a thin film of aluminum deposited on the substrate for surface plasmon resonance analysis. Methods of forming the thin aluminum film substrate and microarrays including providing a substrate, using electron-beam physical vapor deposition (EBPVD) to deposit a thin film of Al on a surface of the substrate. Also disclosed are methods of detecting an analyte, wherein a functionalized surface of the thin aluminum film includes a biomolecule and the methods include applying a sample including the analyte to the thin aluminum film substrate, and using surface plasmon resonance (SPR) spectroscopy to detect molecular interactions between the biomolecule and the analyte at a surface of the thin aluminum film substrate. In some examples, an unmodified Al film with an Al2O3 layer is effective in enriching phosphorylated peptides. In some examples, a coating of an ionic polymer is used to analyze charged-based interactions of biomolecules. |
| FILED | Wednesday, June 08, 2022 |
| APPL NO | 17/805971 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/18 (20130101) C23C 14/30 (20130101) C23C 14/5853 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 49/164 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220397546 | Tabib-Azar |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Massood Tabib-Azar (Salt Lake City, Utah) |
| ABSTRACT | A method for reducing electrode gap distances in an electronic device having a first electrode spatially separated from a second electrode by an electrode gap can comprise selecting (810) a milometer gap size to bind a biological material based on a size of the biological material and binding effects with the biological material. The method can further comprise coating (820) at least one surface of an electrode gap region with a first layer including molecular recognition groups, and coating (830) the at least one surface with a second layer including electrically-conductive solids that are configured to bond with the molecular recognition groups. The electronic device can be further coated (840) with additional alternating layers of the molecular recognition groups and the electrically-conductive solids to reach the nanometer gap size between a first electrode and a second electrode of the electronic device. |
| FILED | Monday, October 26, 2020 |
| APPL NO | 17/770969 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4145 (20130101) Original (OR) Class G01N 27/4146 (20130101) G01N 33/5438 (20130101) G01N 33/56983 (20130101) G01N 2333/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220397552 | Eiceman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GP Ionics LLC (Las Cruces, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gary Alan Eiceman (Las Cruces, New Mexico); Peter Ernest Fowler (Las Cruces, New Mexico) |
| ABSTRACT | A detector system comprises a first analytical stage configured to isolate ions from a sample, a field induced fragmentation stage configured to fragment the ions, a second analytical stage configured to characterize the ions, and at least one detector. The first analytical stage and the second analytical stage each comprise a differential mobility spectrometer. The field induced fragmentation stage comprises strips configured to create an electric field therebetween. In certain embodiments, the system further comprises a port configured between the first analytical stage and the field induced fragmentation stage, configured to introduce a reagent. |
| FILED | Thursday, June 09, 2022 |
| APPL NO | 17/836958 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4044 (20130101) G01N 27/624 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220397660 | MIRBEIK-SABZEVARI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey) |
| INVENTOR(S) | Amir MIRBEIK-SABZEVARI (Hoboken, New Jersey); Negar TAVASSOLIAN (Hoboken, New Jersey) |
| ABSTRACT | The present disclosure relates to an apparatus and method for synthetically making an ultra-wide imaging bandwidth in millimeter-wave frequencies, resulting in improved image resolutions to values previously unattained. The synthetic approach sums up a number of available sub-bands to build an unavailable ultra-wideband system. Each sub-band contains a transceiver unit which is optimized for operation within that specific sub-band. The number and position of the sub-bands can be adjusted to cover any frequency range as required for the specific application. |
| FILED | Friday, June 10, 2022 |
| APPL NO | 17/838033 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/05 (20130101) A61B 5/444 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/03 (20130101) G01S 13/0209 (20130101) Original (OR) Class G01S 13/347 (20130101) G01S 13/9011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220397702 | Guler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Urcan Guler (West Lafayette, Indiana); Alexander V. Kildishev (West Lafayette, Indiana); Krishnakali Chaudhury (West Lafayette, Indiana); Shaimaa Azzam (West Lafayette, Indiana); Esteban E. Marinero-Caceres (West Lafayette, Indiana); Harsha Reddy (West Lafayette, Indiana); Alexandra Boltasseva (West Lafayette, Indiana); Vladimir M. Shalaev (West Lafayette, Indiana) |
| ABSTRACT | An optical sensor system, comprising refractory plasmonic elements that can withstand temperatures exceeding 2500° C. in chemically aggressive and harsh environments that impose stress, strain and vibrations. A plasmonic metamaterial or metasurface, engineered to have a specific spectral and angular response, exhibits optical reflection characteristics that are altered by varying physical environmental conditions including but not limited to temperature, surface chemistry or elastic stress, strain and other types of mechanical load. The metamaterial or metasurface comprises a set of ultra-thin structured layers with a total thickness of less than tens of microns that can be deployed onto surfaces of devices operating in harsh environmental conditions. The top interface of the metamaterial or metasurface is illuminated with a light source, either through free space or via an optical fiber, and the reflected signal is detected employing remote detectors. |
| FILED | Tuesday, March 31, 2020 |
| APPL NO | 16/835302 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/8422 (20130101) Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220399696 | Chevalier et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Henry O. Everitt (Huntsville, Alabama); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); The United States of America as Represented by the Secretary of the Army (Huntsville, Alabama) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); The United States of America as Represented by the Secretary of the Army (Huntsville, Alabama) |
| INVENTOR(S) | Paul Chevalier (Cambridge, Massachusetts); Arman Amirzhan (Cambridge, Massachusetts); Marco Piccardo (Cambridge, Massachusetts); Fan Wang (Cambridge, Massachusetts); Steven Glen Johnson (Cambridge, Massachusetts); Henry O. Everitt (Huntsville, Alabama); Federico CAPASSO (Cambridge, Massachusetts) |
| ABSTRACT | Disclosed is a laser system including a first laser and a second laser. The first laser includes a laser cavity, and a gas phase molecular gain medium disposed in the laser cavity, the gain medium having an absorption band. The second laser is a solid state laser configured to be continuously tunable, with respect to an emission wavelength of the second laser, over the absorption band of the gain medium, and the second laser is tuned to pump rotational vibrational transitions in the gain medium to achieve a rotational population inversion. |
| FILED | Thursday, November 12, 2020 |
| APPL NO | 17/776547 |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/1312 (20130101) Original (OR) Class H01S 3/09415 (20130101) H01S 2302/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220399755 | Arnold et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David P. Arnold (Gainesville, Florida); Alexandra Garraud (Gainesville, Florida); Nicolas Garraud (Gainesville, Florida) |
| ABSTRACT | The present disclosure relates to systems and methods for tunable electrodynamic wireless power receivers. In some examples, a wireless power receiver electromechanically converts energy from a magnetic field using an oscillating or continuously rotating magnet. A sensing device detects an operational parameter of the receiver, and a tuning device initiates a tuning action based on the operational parameter. |
| FILED | Thursday, November 12, 2020 |
| APPL NO | 17/776925 |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/12 (20160201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220400375 | Schmitt |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Paul Schmitt (Palo Alto, California) |
| ABSTRACT | According to various embodiments, a cellular architecture for enhanced privacy regarding identity and location of a computing device is disclosed. The architecture includes a next generation core (NGC). The NGC includes an authentication server function (AUSF) configured to determine whether the computing device contains a valid subscriber identity module (SIM) card, and a user plane function (UPF) configured to allow a computing device to connect to the Internet. The architecture further includes a gateway connected to the UPF, the gateway configured to authenticate the computing device while hiding the identity of the computing device by verifying authentication tokens that represent units of access. |
| FILED | Tuesday, March 02, 2021 |
| APPL NO | 17/419895 |
| CURRENT CPC | Wireless Communication Networks H04W 4/24 (20130101) H04W 12/02 (20130101) Original (OR) Class H04W 12/06 (20130101) H04W 12/40 (20210101) H04W 12/63 (20210101) H04W 12/72 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20220395780 | Bhave et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ramesh R. Bhave (Oak Ridge, Tennessee); Syed Z. Islam (Oak Ridge, Tennessee); Priyesh A. Wagh (Oak Ridge, Tennessee) |
| ABSTRACT | A method of concentrating lithium containing solutions includes inputting a feed brine solution to an initial separation stage, the feed brine solution including lithium sulfate and one or more of sodium sulfate, potassium sulfate, calcium sulfate, and sodium chloride dissolved in water. In the initial separation stage, the feed brine solution is introduced to a pre-treatment membrane at a pressure that is less than the osmotic pressure of the feed brine solution. An initial permeate that passes through the pre-treatment membrane becomes the feed to a final separation stage, and an initial retentate that does not pass through the pre-treatment membrane includes a precipitate of at least one of the salts other than lithium sulfate. In the final separation stage, the initial permeate is introduced to a nanofiltration membrane at a pressure that is less than the osmotic pressure of the initial permeate. A final retentate that does not pass through the nanofiltration membrane is combined with the initial retentate to obtain a product solution having a higher concentration of dissolved lithium sulfate than the feed brine solution. |
| FILED | Thursday, June 09, 2022 |
| APPL NO | 17/836088 |
| CURRENT CPC | Separation B01D 61/04 (20130101) B01D 61/025 (20130101) B01D 61/027 (20130101) B01D 61/029 (20220801) B01D 61/58 (20130101) Original (OR) Class B01D 61/145 (20130101) B01D 61/0271 (20220801) B01D 63/06 (20130101) B01D 63/10 (20130101) B01D 69/02 (20130101) B01D 2311/04 (20130101) B01D 2311/08 (20130101) B01D 2317/08 (20130101) B01D 2317/025 (20130101) B01D 2325/20 (20130101) Compounds of Alkali Metals, i.e Lithium, Sodium, Potassium, Rubidium, Caesium, or Francium C01D 15/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396484 | Wiesner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CORNELL UNIVERSITY (lthaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ulrich B. Wiesner (Ithaca, New York); Sarah A. Hesse (Redwood City, California); Kevin E. Fritz (Flemington, New Jersey); Peter A. Beaucage (Germantown, Maryland); Jin Suntivich (Ithaca, New York) |
| ABSTRACT | Asymmetric porous films, methods of making, and devices. An asymmetric porous film may have a surface layer, which may be an isoporous surface layer, disposed on a substructure, which may be a graded porous substructure that may have mesopores throughout. An asymmetric porous film may be a hybrid asymmetric porous film comprising one or more precursor(s). An asymmetric porous film may include one or more carbon material(s), one or more metalloid oxide(s), one or more metal(s), one or more metal oxide(s), one or more metal nitride(s), one or more metal oxynitride(s), one or more metal carbide(s), one or more metal carbonitrides, or a combination thereof. A method of making an asymmetric porous film may comprise formation of an asymmetric porous film using CA a mixture comprising a multiblock copolymer that can self-assemble and one or more precursor(s). |
| FILED | Tuesday, November 03, 2020 |
| APPL NO | 17/772542 |
| CURRENT CPC | Separation B01D 71/021 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/05 (20170801) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2006/16 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/583 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396504 | Geelhoed |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | FERMI RESEARCH ALLIANCE, LLC (Batavia, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Geelhoed (North Aurora, Illinois) |
| ABSTRACT | A method and system for water purification includes a particle accelerator configured to generate a particle beam and a conduit configured to be substantially in line with the particle beam wherein said electron beam is incident on a fluid flowing through the conduit. The electron beam can be oriented to be substantially head on to the direction of flow of the fluid in the conduit. A shielding assembly can be configured around the conduit. A cartridge filtering system and contaminant filtering system can be provided to remove additional contaminants. |
| FILED | Thursday, August 18, 2022 |
| APPL NO | 17/890908 |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/001 (20130101) C02F 1/283 (20130101) C02F 1/305 (20130101) Original (OR) Class C02F 1/441 (20130101) C02F 2209/40 (20130101) C02F 2303/04 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 7/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396516 | Visco et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PolyPlus Battery Company (Berkeley, California) |
| ASSIGNEE(S) | PolyPlus Battery Company (Berkeley, California) |
| INVENTOR(S) | Steven J. Visco (Berkeley, California); Yevgeniy S. Nimon (Danville, California); Bruce D. Katz (Moraga, California); Vitaliy Nimon (San Francisco, California); Alexei Petrov (Walnut Creek, California) |
| ABSTRACT | A standalone lithium ion-conductive sulfide solid electrolyte can include a freestanding inorganic vitreous sheet of sulfide-based lithium ion conducting glass capable of high performance in a lithium metal battery by providing a high degree of lithium-ion conductivity while being highly resistant to the initiation and/or propagation of lithium dendrites. Such an electrolyte is also itself manufacturable, and readily adaptable for battery cell and cell component manufacture, in a cost-effective, scalable manner. Methods of making and using the electrolyte, and battery cells and cell components incorporating the electrolyte are also disclosed. |
| FILED | Friday, April 08, 2022 |
| APPL NO | 17/658646 |
| CURRENT CPC | Manufacture, Shaping, or Supplementary Processes C03B 11/00 (20130101) C03B 13/16 (20130101) Original (OR) Class Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 3/321 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/052 (20130101) H01M 10/0562 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396789 | Banal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James L. Banal (Cambridge, Massachusetts); Mark Bathe (Cambridge, Massachusetts); Joseph Berleant (Cambridge, Massachusetts); Charles E. Leiserson (Cambridge, Massachusetts); Tao Benjamin Schardl (Cambridge, Massachusetts) |
| ABSTRACT | Disclosed are compositions and methods relating to sequence-controlled storage objected. The disclosed sequence-controlled storage objects can include (a) one or more different sequence-controlled polymers, and (b) a plurality of different feature tags. The sequence-controlled storage object can include (a) one or more different sequence-controlled polymers, and (b) a plurality of different digit tags. Also disclosed are methods of storing desired sequence-controlled polymers as a sequence-controlled storage object, comprising assembling a sequence-controlled storage object from (i) one or more different sequence-controlled polymers, (ii) a plurality of different feature tags, and (iii) optionally one or more encapsulating agents. Also disclosed are methods of automating the assembly of a sequence-controlled storage object comprising using a device with flow. |
| FILED | Thursday, June 09, 2022 |
| APPL NO | 17/836726 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) Original (OR) Class C12N 15/1089 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396811 | Fedorov |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrei Fedorov (Atlanta, Georgia) |
| ABSTRACT | The present disclosure provides for methods of delivering cargo material to a cell(s) in vivo or in vitro, devices configured to deliver cargo material to the cell, systems configured to deliver cargo material to the cell, and the like. The present disclosure can synergistically combine multiple technologies to improve the rate of cargo material introduction and utility of physical cellular modification in a transformative way compared to the current microinjection state-of-the art. |
| FILED | Monday, November 23, 2020 |
| APPL NO | 17/756088 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 5/00 (20130101) B01L 2400/0442 (20130101) Apparatus for Enzymology or Microbiology; C12M 35/02 (20130101) C12M 35/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/895 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396812 | Doudna et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jennifer A. Doudna (Berkeley, California); Jillian F. Banfield (Berkeley, California); David Burstein (Berkeley, California); Lucas Benjamin Harrington (Berkeley, California) |
| ABSTRACT | The present disclosure provides CasY proteins, nucleic acids encoding the CasY proteins, and modified host cells comprising the CasY proteins and/or nucleic acids encoding same. CasY proteins are useful in a variety of applications, which are provided. The present disclosure provides CasY guide RNAs that bind to and provide sequence specificity to the CasY proteins, nucleic acids encoding the CasY guide RNAs, and modified host cells comprising the CasY guide RNAs and/or nucleic acids encoding same. CasY guide RNAs are useful in a variety of applications, which are provided. The present disclosure provides methods of identifying a CRISPR RNA-guided endonuclease. |
| FILED | Thursday, May 19, 2022 |
| APPL NO | 17/749017 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/46 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/113 (20130101) C12N 15/902 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2740/16043 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396883 | Freiderich |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Melissa Ensor Freiderich (Oak Ridge, Tennessee) |
| ABSTRACT | Systems and methods for electroless plating a first metal onto a second metal in a molten salt bath including: a bath vessel holding a dry salt mixture including a dry salt medium and a dry salt medium of the first metal, and without the reductant therein, the dry salt mixture configured to be heated to form a molten salt bath; and the second metal is configured to be disposed in the molten salt bath and receive a pure coating of the first metal thereon by electroless plating in the molten salt bath, wherein the second metal is more electronegative than the first metal. |
| FILED | Monday, June 14, 2021 |
| APPL NO | 17/346504 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 18/31 (20130101) Original (OR) Class C23C 18/1637 (20130101) C23C 18/1676 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396926 | MILLER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Triton Systems, Inc. (Chelmsford, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zachary MILLER (Nashua, New Hampshire); William FEATHER (Merrimack, New Hampshire); Nathan KROHN (Pearland, Texas); Tyson LAWRENCE (Highlands Ranch, Colorado); Jihan ELJADIDI (Cambridge, Maryland); Tyler ROBERTSON (North Attleboro, Massachusetts); Raf MANDUJANO (Arlington, Maryland) |
| ABSTRACT | Disclosed herein are a group anchor system, subsea installation tool and method of install such group anchor systems. The group anchor system includes a template through which a plurality of vertical piles, such as helical piles, are passed, drilled into the seabed at one end and secured to the template at the other to provide a mooring anchor for an offshore asset. The installation tool is a modular tool designed to mate with the group anchor system. Each module including drive mechanism for engaging and driving a pile. The piles may be driven simultaneously, individually, or in groups as required for proper placement and leveling. Methods of using the installation tool are also disclosed. |
| FILED | Friday, June 10, 2022 |
| APPL NO | 17/838025 |
| CURRENT CPC | Foundations; Excavations; Embankments; Underground or Underwater Structures E02D 5/56 (20130101) E02D 7/22 (20130101) Original (OR) Class E02D 2200/1671 (20130101) E02D 2250/0061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220397033 | Babakhani |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Aydin Babakhani (Los Angeles, California) |
| ABSTRACT | Systems and methods for transmitting power to wirelessly powered sensors using a pipeline as a circular waveguide are disclosed. In an embodiment, a transmitter transmits electromagnetic waves to at least one wirelessly powered sensor positioned along the pipeline, wherein the pipeline is used as a waveguide to transmit the electromagnetic waves using a particular waveguide mode form of electromagnetic radiation, where the at least one wirelessly powered sensor is configured to be operated without a battery and to be powered by the electromagnetic waves emitted by the electromagnetic transmitter and senses at least one characteristic of the pipeline. |
| FILED | Monday, December 28, 2020 |
| APPL NO | 17/758114 |
| CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 47/135 (20200501) Original (OR) Class Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 3/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220397531 | ANGEL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF SOUTH CAROLINA (COLUMBIA, South Carolina); LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (LIVERMORE, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | STANLEY MICHAEL ANGEL (COLUMBIA, South Carolina); JERRY CHANCE CARTER (LIVERMORE, California) |
| ABSTRACT | A hyperspectral imaging apparatus based on a monolithic or free space optical spatial heterodyne spectrometer (SHS) design, array detector, electromagnetic radiation source, and optical collection element is described. The apparatus enables the simultaneous acquisition of spatially isolated Fizeau fringe patterns, each having an encoded light product that is decoded to produce a spectral fingerprint of the interrogated object. Features specific to the SHS, such as a large entrance aperture, large acceptance angle, and no moving parts, enable a variety of optical collection schemes including lens arrays, solid-core and hollow core waveguides, and others. In one example, a microlens array (MLA) is configured with the hyperspectral imaging apparatus to simultaneously image many hundred spatially isolated Fizeau fringe patterns while interrogating an object using an electromagnetic radiation source. Each Fizeau fringe pattern recorded by the array detector is decoded to produce a full Raman or laser-induced breakdown spectroscopy (LIBS) spectrum. Compared to prior art, the hyperspectral imaging apparatus overcomes the primary limitations of needing to trade time resolution for both spectral and spatial data density because the imaging apparatus simultaneously acquires both spectral and special information. Based on the selection and configuration of diffraction gratings, the grating aperture size, Littrow wavelength (i.e., heterodyne wavelength), and optical collection configuration, the apparatus can be tailored to produced low or high spectral resolution with a spectral bandpass that covers a portion or the entire Raman spectral range (up to 4200 cm−1) and for LIBS as well. |
| FILED | Monday, November 11, 2019 |
| APPL NO | 17/772265 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) Original (OR) Class G01N 2201/0633 (20130101) G01N 2201/0635 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220397597 | Schantz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Eric T. Schantz (Overland Park, Kansas); Cody William Durand (Kansas City, Missouri); Ryan Michael Soroka (Overland Park, Kansas) |
| ABSTRACT | A system for monitoring electrostatic charge buildup and electrostatic discharge (ESD) remotely comprises a plurality of electrostatic charge measurement units and a data acquisition device. Each electrostatic charge measurement unit includes a primary charge plate, a static sensor device, a secondary charge plate, and a shielded cable. The primary charge plate is positioned proximal to an object. The static sensor device includes an input sensor at which an electric voltage is measured and outputs an electronic signal whose level varies according to the measured electric voltage. The secondary charge plate is positioned in proximity to the input sensor of the static sensor device. The shielded cable includes an inner conductor electrically connected to the primary charge plate and the secondary charge plate and an outer conductor electrically connected to electrical ground. The data acquisition device receives the electronic signal from the static sensor device of each electrostatic charge measurement unit. |
| FILED | Wednesday, June 09, 2021 |
| APPL NO | 17/342707 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 29/12 (20130101) Original (OR) Class G01R 31/001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220398873 | CANOVA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Marcello CANOVA (Columbus, Ohio); Shreshta RAJAKUMAR DESHPANDE (Columbus, Ohio); Shobhit GUPTA (Columbus, Ohio); Abhishek GUPTA (Columbus, Ohio) |
| ABSTRACT | The use of multiple horizon optimization for vehicle dynamics and powertrain control of a vehicle is provided. Long horizon optimization for a trip of the vehicle is performed, and an optimal value function is determined. Data is received from powertrain and/or connectivity features from one or more of components of the vehicle. Short horizon optimization for the trip is performed using a rollout algorithm, the optimal value function, and the received data. The operation of the vehicle is adjusted using results of the short horizon optimization. |
| FILED | Friday, November 06, 2020 |
| APPL NO | 17/774677 |
| CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 40/105 (20130101) B60W 2510/10 (20130101) Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere G07C 5/02 (20130101) G07C 5/008 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220399137 | Shu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Deming Shu (Darien, Illinois); Steven P. Kearney (Schaumberg, Illinois); Jayson W. Anton (Chicago, Illinois); William F. Toter (Park Ridge, Illinois) |
| ABSTRACT | A method and a novel flexure interface apparatus are provided for ultrahigh-vacuum (UHV) applications for precision nanopositioning systems. An ultrahigh-vacuum (UHV) metrology base is integrated with an ultrahigh-vacuum (UHV) flange together including a precision and compact flexure interface structure defining a UHV metrology base near-zero-length feedthrough. The UHV metrology base is directly mounted to a flange mounting surface in air with nanopositioning and thermal stability. The precision and compact flexure interface structure has sufficient strength to hold the vacuum force and sufficiently flexible to survive with the thermal expansion stress during bakeout process. |
| FILED | Monday, June 14, 2021 |
| APPL NO | 17/346537 |
| CURRENT CPC | Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220399153 | Mukherjee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Satyaki Mukherjee (Boulder, Colorado); Branko Majmunovic (Boulder, Colorado); Dragan Maksimovic (Boulder, Colorado); Brian B. Johnson (Seattle, Washington) |
| ABSTRACT | Various embodiments of the present disclosure relate to power conversion using a planar transformer assembly that provides medium-voltage isolation at high frequencies. A planar transformer comprises primary and secondary planar windings configured to generate an isolated output. Each primary and secondary winding is interleaved on layers of a printed circuit board using one or more vias within the layers of the printed circuit board. The planar transformer also comprises a magnetic core and a field-shaping apparatus coupled with the printed circuit board. The field-shaping apparatus is configured to shape an electric field generated by the windings. The primary windings can be coupled to a DC source via switching devices while the secondary windings can be coupled via switching devices to one or more DC ports followed by AC inverters configured to generate three single-phase AC outputs for medium voltage applications. |
| FILED | Tuesday, June 14, 2022 |
| APPL NO | 17/839924 |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 27/24 (20130101) H01F 27/2804 (20130101) Original (OR) Class H01F 41/041 (20130101) H01F 2027/2809 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 5/4585 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/115 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220399514 | FORREST et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen R. FORREST (Ann Arbor, Michigan); Dejiu FAN (Ann Arbor, Michigan); Xinjing Huang (Ann Arbor, Michigan) |
| ABSTRACT | An ultra-thin shadow mask comprises a plastic foil including a plurality of apertures, wherein the ultra-thin shadow mask is less than 25 μm thick, and wherein the ultra-thin shadow mask has a feature size of at least 1 μm to about 100 μm. An organic photovoltaic (OPV) device comprises a first electrode including a first grid structure, the first grid structure having a feature size of at least 1 μm to about 100 μm, a heterojunction under the first electrode, a second electrode under the heterojunction including a second grid structure, and a plurality of outcoupling layers over the first electrode. Related methods are also disclosed. |
| FILED | Wednesday, June 15, 2022 |
| APPL NO | 17/840800 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/301 (20130101) H01L 51/0036 (20130101) H01L 51/0071 (20130101) H01L 51/445 (20130101) Original (OR) Class H01L 51/4253 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220399541 | Dai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Apple Inc. (Cupertino, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hongli Dai (Los Altos, California); Huiming Wu (San Jose, California); Dapeng Wang (Cupertino, California); John David Carter (Bolingbrook, Illinois); Yan Li (Westmont, Illinois); Anh D. Vu (Lemont, Illinois); Xiaoping Wang (Naperville, Illinois); Christopher S. Johnson (Naperville, Illinois); Rui Xu (Lemont, Illinois); Zhenzhen Yang (Westmont, Illinois); Yanjie Cui (Arlington Heights, Illinois); James A. Gilbert (Bolingbrook, Illinois); Arthur Jeremy Kropf (Westmont, Illinois); Hakim H. Iddir (Hoffman Estates, Illinois) |
| ABSTRACT | Compounds, particles, and cathode active materials that can be used in lithium ion batteries are described herein. Methods of making such compounds, powders, and cathode active materials are described. The particles have a particle size distribution with a D50 ranging from 10 μm to 20 μm. |
| FILED | Thursday, August 11, 2022 |
| APPL NO | 17/886096 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/0435 (20130101) H01M 4/0471 (20130101) H01M 4/505 (20130101) Original (OR) Class H01M 4/525 (20130101) H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220399543 | Lu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Yanying Lu (El Cerrito, California); Guoying Chen (Oakland, California) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus related to lithium-ion batteries. In one aspect, a method includes synthesizing an intermediate selected from a group of a nickel-manganese-cobalt nitrate, a nickel-manganese-cobalt acetate, a nickel-manganese-cobalt sulfate, a nickel-manganese-cobalt chloride, and a nickel-manganese-cobalt phosphate. The intermediate is mixed with a lithium salt selected from a group of LiOH, LiCl, LiNO3, LiSO4, LiF, LiBr, Li3PO4, Li2CO3, and combinations thereof to form a mixture. The mixture is annealed at a sequence of temperatures and times to form a plurality of single crystals of a lithium nickel-manganese-cobalt oxide, with no cooling of the mixture between operations of the sequence of temperatures and times. |
| FILED | Tuesday, June 07, 2022 |
| APPL NO | 17/834076 |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 53/50 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/0497 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) Original (OR) Class H01M 10/0525 (20130101) H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220399567 | Visco et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PolyPlus Battery Company (Berkeley, California) |
| ASSIGNEE(S) | PolyPlus Battery Company (Berkeley, California) |
| INVENTOR(S) | Steven J. Visco (Berkeley, California); Yevgeniy S. Nimon (Danville, California); Bruce D. Katz (Moraga, California) |
| ABSTRACT | A standalone lithium ion-conductive sulfide solid electrolyte can include a freestanding inorganic vitreous sheet of sulfide-based lithium ion conducting glass capable of high performance in a lithium metal battery by providing a high degree of lithium-ion conductivity while being highly resistant to the initiation and/or propagation of lithium dendrites. Such an electrolyte is also itself manufacturable, and readily adaptable for battery cell and cell component manufacture, in a cost-effective, scalable manner. Methods of making and using the electrolyte, and battery cells and cell components incorporating the electrolyte are also disclosed. |
| FILED | Friday, April 08, 2022 |
| APPL NO | 17/658645 |
| CURRENT CPC | Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 3/321 (20130101) C03C 4/14 (20130101) C03C 2204/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0562 (20130101) Original (OR) Class H01M 50/403 (20210101) H01M 50/437 (20210101) H01M 2300/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220399569 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Guoying Chen (Oakland, California); Se Young Kim (Emeryville, California); Yanying Lu (El Cerrito, California) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus related to composite cathodes for all solid-state batteries. In one aspect, an all solid-state battery comprises a composite cathode, a separator, and an anode. The composite cathode comprises LiNixMnyCo1-x-yO2, x≥0.33, with about 80% or more of the LiNixMnyCo1-x-yO2 comprising single crystals of LiNixMnyCo1-x-yO2. The LiNixMnyCo1-x-yO2 is embedded in a matrix of a first lithium metal halide solid electrolyte comprising Li6-3aMaX6, 0<a<2. M is an element from a group of magnesium (Mg), calcium (Ca), strontium (Sr), barium (Ba), scandium (Sc), indium (In), zirconium (Zr), niobium (Nb), hafnium (Hf), tantalum (Ta), yttrium (Y), lanthanum (La), samarium (Sm), bismuth (Bi), holmium (Ho), erbium (Er), ytterbium (Yb), and combinations thereof. X is a halide from a group of chlorine (Cl), bromine (Br), iodine (I), and combinations thereof. |
| FILED | Monday, June 13, 2022 |
| APPL NO | 17/838457 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/134 (20130101) H01M 4/525 (20130101) H01M 10/0525 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2300/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20220395391 | SAUNDERS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | TRITON SYSTEMS, INC. (CHELMSFORD, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James F. SAUNDERS (Lowell, Massachusetts); Tyson LAWRENCE (Highlands Ranch, Colorado); Samantha BURDETT (Lowell, Massachusetts); Michael J. GUARINO (Wakefield, Massachusetts); Cole GODZINSKI (North Reading, Massachusetts); Kim HALLETT (Rochester, New Hampshire); Connor ADAMIK (Medford, Massachusetts); Maciej PIETRUSINSKI (Boston, Massachusetts); Olivia CHONG (Somerville, Massachusetts) |
| ABSTRACT | Disclosed herein is a bladder collection system. Particularly, a bladder collection system for females is disclosed. The system is designed to be flexible and useful in upright or mobile situations. The bladder relief system includes a collection interface sized and configured for seated or standing application, a sleeve, defining a collection opening, and sidewalls defining a collection cavity, an interface tubing, extending from one end of the sleeve to another, between a collection end of the interface tubing, and an exit port for connection to an exit hose; and an adsorbing material contained within the collection cavity. |
| FILED | Friday, June 10, 2022 |
| APPL NO | 17/838105 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 5/451 (20130101) Original (OR) Class A61F 5/4401 (20130101) A61F 5/4404 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220395486 | AREA-GOMEZ et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Estela AREA-GOMEZ (New York, New York); Eric A. SCHON (Bronx, New York) |
| ABSTRACT | The invention provides for methods for treating Alzheimer's Disease in a subject by reducing ER-MAM localized APP-C99. |
| FILED | Friday, January 28, 2022 |
| APPL NO | 17/588104 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/11 (20130101) A61K 31/37 (20130101) A61K 31/40 (20130101) A61K 31/55 (20130101) A61K 31/137 (20130101) A61K 31/166 (20130101) A61K 31/192 (20130101) A61K 31/197 (20130101) A61K 31/327 (20130101) A61K 31/366 (20130101) A61K 31/397 (20130101) Original (OR) Class A61K 31/513 (20130101) A61K 31/519 (20130101) A61K 31/566 (20130101) A61K 31/675 (20130101) A61K 31/4188 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220395585 | Weiss et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Kyoto University (Kyoto, Japan) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Kyoto University (Kyoto, Japan) |
| INVENTOR(S) | Ron Weiss (Newton, Massachusetts); Liliana Wroblewska (Wilmington, Massachusetts); Velia Siciliano (Naples, Italy); Tasuku Kitada (Ghent, Belgium); Maria Hottelet Foley (Cambridge, Massachusetts); Katie Bodner (Stanford, California); Hirohide Saito (Kyoto, Japan); Kei Endo (Chiba, Japan); Darrell J. Irvine (Arlington, Massachusetts); Tyler Wagner (Bel Air, Maryland); Jacob Becraft (Boston, Massachusetts) |
| ABSTRACT | Engineered synthetic RNA-based genetic circuits are provided that are regulated exclusively at the post-transcriptional level. |
| FILED | Tuesday, May 03, 2022 |
| APPL NO | 17/735627 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0066 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/10 (20130101) C12N 15/63 (20130101) C12N 15/85 (20130101) C12N 2840/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396353 | COVINGTON et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bell Textron Inc. (Fort Worth, Texas) |
| ASSIGNEE(S) | Bell Textron Inc. (Fort Worth, Texas) |
| INVENTOR(S) | Charles Eric COVINGTON (Colleyville, Texas); Chia-Wei SU (Lewisville, Texas); Darren Gregory LANG (Dallas, Texas); Thomas PARSONS (Fort Worth, Texas); Cody Earl FEGELY (Irving, Texas) |
| ABSTRACT | A rotorcraft has a drive system including a main rotor coupled to a main rotor gearbox to rotate the main rotor at a rotor speed, a main engine coupled to the drive system to provide a first power, a supplemental engine coupled, when a first clutch is engaged, to the drive system to provide a second power additive to the first power, and a control system operable to control the main engine and the supplemental engine to provide a total power demand, where the main engine is controlled based on variations in rotor speed and a power compensation command to produce the first power, and the supplemental engine is controlled to produce the second power in response to a supplemental power demand. |
| FILED | Wednesday, June 09, 2021 |
| APPL NO | 17/342963 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/12 (20130101) Original (OR) Class B64C 27/26 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 35/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396789 | Banal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James L. Banal (Cambridge, Massachusetts); Mark Bathe (Cambridge, Massachusetts); Joseph Berleant (Cambridge, Massachusetts); Charles E. Leiserson (Cambridge, Massachusetts); Tao Benjamin Schardl (Cambridge, Massachusetts) |
| ABSTRACT | Disclosed are compositions and methods relating to sequence-controlled storage objected. The disclosed sequence-controlled storage objects can include (a) one or more different sequence-controlled polymers, and (b) a plurality of different feature tags. The sequence-controlled storage object can include (a) one or more different sequence-controlled polymers, and (b) a plurality of different digit tags. Also disclosed are methods of storing desired sequence-controlled polymers as a sequence-controlled storage object, comprising assembling a sequence-controlled storage object from (i) one or more different sequence-controlled polymers, (ii) a plurality of different feature tags, and (iii) optionally one or more encapsulating agents. Also disclosed are methods of automating the assembly of a sequence-controlled storage object comprising using a device with flow. |
| FILED | Thursday, June 09, 2022 |
| APPL NO | 17/836726 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) Original (OR) Class C12N 15/1089 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396946 | Peterson |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Folding Holdings, LLC (Bothell, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Elliot Peterson (Bothell, Washington) |
| ABSTRACT | A built-up beam includes a pair of I-beams each having opposing flanges, a web that extends between the opposing flanges, a plurality of flange openings in each of the opposing flanges, a plurality of web openings in the web, and a plurality of bolt holes in one of the opposing flanges. The I-beams are stacked together flange-to-flange in a stacked beam configuration and a plurality of bolts extend through the plurality of bolt holes and secure the pair of I-beams together in the stacked beam configuration. |
| FILED | Friday, January 28, 2022 |
| APPL NO | 17/588020 |
| CURRENT CPC | Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 13/02 (20130101) B23P 15/00 (20130101) General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/19 (20130101) Original (OR) Class Structural Elements; Building Materials E04C 3/04 (20130101) E04C 3/14 (20130101) E04C 2003/0413 (20130101) E04C 2003/0452 (20130101) E04C 2003/0465 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49364 (20150115) Y10T 29/49963 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220397150 | Gald et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew Gald (Tucson, Arizona); Stephen J. Forgacs (Tucson, Arizona); Dan L. Reller (Vail, Arizona); Dean J. Cornelius (Tucson, Arizona) |
| ABSTRACT | A hinge includes internal on-axis stopping mechanisms that cause the hinge to shear and break at an on-axis weakened region of the hinge when rotation of the hinge reaches a predetermined angle with a specified torsional load. The on-axis configuration is compact, has minimal impact on the outer mold line (OML) of the object to which it is mounted both pre and post detachment and allows for accurate tailoring of the torsional load that will detach the hinge. |
| FILED | Tuesday, June 15, 2021 |
| APPL NO | 17/348371 |
| CURRENT CPC | Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 11/12 (20130101) Original (OR) Class Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 10/64 (20130101) F42B 14/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220397267 | Tuttle |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven G Tuttle (Brandywine, Maryland) |
| ABSTRACT | An atomizer includes an endcap having a nozzle; an annular sidewall extending outward from a surface of the endcap and situated radially outward from the nozzle; and a plurality of vanes extending radially inward from the sidewall and axially outward from the endcap, the vanes being set at a non-zero angle of incidence to the sidewall. The annular sidewall and endcap define an fluid chamber between an inlet and the nozzle, and flow from the inlet to the nozzle is at least partially directed through passageways between the vanes, and the flow is imparted with swirling motion from the vanes. |
| FILED | Thursday, June 10, 2021 |
| APPL NO | 17/343846 |
| CURRENT CPC | Burners F23D 11/107 (20130101) Original (OR) Class Regulating or Controlling Combustion F23N 1/027 (20130101) F23N 2237/14 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220397383 | HAMERLY et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ryan HAMERLY (Cambridge, Massachusetts); Saumil Bandyopadhyay (Cambridge, Massachusetts); Dirk Robert ENGLUND (Brookline, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ryan HAMERLY (Cambridge, Massachusetts); Saumil Bandyopadhyay (Cambridge, Massachusetts); Dirk Robert ENGLUND (Brookline, Massachusetts) |
| ABSTRACT | Component errors prevent linear photonic circuits from being scaled to large sizes. These errors can be compensated by programming the components in an order corresponding to nulling operations on a target matrix X through Givens rotations X→T†X, X→XT†. Nulling is implemented on hardware through measurements with feedback, in a way that builds up the target matrix even in the presence of hardware errors. This programming works with unknown errors and without internal sources or detectors in the circuit. Modifying the photonic circuit architecture can reduce the effect of errors still further, in some cases even rendering the hardware asymptotically perfect in the large-size limit. These modifications include adding a third directional coupler or crossing after each Mach-Zehnder interferometer in the circuit and a photonic implementation of the generalized FFT fractal. The configured photonic circuit can be used for machine learning, quantum photonics, prototyping, optical switching/multicast networks, microwave photonics, or signal processing. |
| FILED | Friday, April 01, 2022 |
| APPL NO | 17/711640 |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/0207 (20130101) Original (OR) Class G01B 9/02027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220399458 | Cui et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Peng Cui (Jinan, China PRC); Yuping Zeng (Newark, Delaware) |
| ASSIGNEE(S) | University of Delaware (Newark, Delaware) |
| INVENTOR(S) | Peng Cui (Jinan, China PRC); Yuping Zeng (Newark, Delaware) |
| ABSTRACT | A semiconductor device and fabricating method thereof is disclosed. The method comprises depositing epitaxial layers over a silicon substrate to form a semiconductor layer surface; forming at least one mesa portion on the semiconductor layer surface; depositing a metal stack on the semiconductor layer surface; subjecting the semiconductor layer surface to a rapid thermal annealing system for a two-step ohmic contact annealing in H2/N2 forming gas (FG) and then nitrogen; subjecting the semiconductor layer surface to an oxygen plasma treatment; and depositing a T-shaped metal gate on the semiconductor layer surface. A semiconductor device comprises a semiconductor layer surface having an epitaxial layer disposed over a silicon substrate; at least one mesa portion formed on the semiconductor layer surface; a metal stack, disposed on the semiconductor layer surface, and sequentially annealed in FG and nitrogen; and a T-shaped metal gate on the semiconductor layer surface. |
| FILED | Thursday, June 09, 2022 |
| APPL NO | 17/836487 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0254 (20130101) H01L 21/02271 (20130101) H01L 21/02293 (20130101) H01L 21/02458 (20130101) H01L 21/3245 (20130101) H01L 29/2003 (20130101) H01L 29/7786 (20130101) H01L 29/66462 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220399475 | Khan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Kamruzzaman Khan (Ann Arbor, Michigan); Elaheh Ahmadi (Ann Arbor, Michigan); Stacia Keller (Santa Barbara, California); Christian Wurm (Isla Vista, California); Umesh K. Mishra (Montecito, California) |
| ABSTRACT | A substrate comprising a III-N base layer comprising a first portion and a second portion, the first portion of the III-N base layer having a first natural lattice constant and a first dislocation density; and a first III-N layer having a second natural lattice constant and a second dislocation density on the III-N base layer, the first III-N layer having a thickness greater than 10 nm. An indium fractional composition of the first III-N layer is greater than 0.1; the second natural lattice constant is at least 1% greater than the first natural lattice constant; a strain-induced lattice constant of the first III-N layer is greater than 1.0055 times the first natural lattice constant; and the second dislocation density is less than 1.5 times the first dislocation density. |
| FILED | Friday, January 14, 2022 |
| APPL NO | 17/576716 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/002 (20130101) H01L 33/32 (20130101) Original (OR) Class H01L 33/0075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220399542 | Durstock et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States as represented by the Secretary of the Air Force (Wright Patterson AFB, Ohio) |
| ASSIGNEE(S) | Government of the United States as represented by the Secretary of the Air Force (Wright Patterson AFB, Ohio) |
| INVENTOR(S) | Michael F. Durstock (West Chester, Ohio); Ryan R. Kohlmeyer (Dayton, Ohio); Aaron J. Blake (Huber Heights, Ohio) |
| ABSTRACT | A method of applying a separator ink onto a dried electrode of a lithium ion battery. The method includes preparing a separator ink suspension, applying the separator ink suspension onto the dried electrode, and drying the applied separator ink suspension. The separator ink suspension includes a binder comprising 20 wt % to 50 wt % of a total weight of the separator ink suspension, the binder being selected from the group consisting of polyvinylidene fluoride (PVDF), polyvinylidene fluoride-co-hexafluoropropylene (PVDF-HFP), polytetrafluoroethylene (PTFE), poly(ethylene oxide) (PEO), Poly(methyl methacrylate (PMMA), polyacrylonitrile (PAN), carboxymethyl cellulose (CMC), styrene-butadiene rubber (SBR), and combinations thereof, a solvent selected from the group consisting of N-methyl-2-pyrrolidone (NMP), dimethylformamide (DMF), acetone, dimethylacetamide (DMAc), dimethyl sulfoxide (DMSO), trimethyl urea, triethyl phosphate, and combinations thereof, a non-solvent selected from the group consisting of glycerol, water, ethanol, methanol, ethylene glycol, diethylene glycol, triethylene glycol, hexane, heptane, and combinations thereof, and a ceramic filler comprising 50 wt % to 80 wt % of the total weight of the composite electrolyte the ceramic filler being selected from the group consisting of Al2O3, SiO2, TiO2, MgO, Li2O, LiAlO2, BaTiO3, lithium aluminum germanium phosphate (LAGP), lithium aluminum titanium phosphate (LATP), lithium lanthanum titanate (LLTO), and combinations thereof. |
| FILED | Friday, April 15, 2022 |
| APPL NO | 17/722272 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/66 (20130101) H01M 4/0409 (20130101) H01M 4/485 (20130101) H01M 4/525 (20130101) Original (OR) Class H01M 4/622 (20130101) H01M 4/623 (20130101) H01M 4/624 (20130101) H01M 4/625 (20130101) H01M 4/5825 (20130101) H01M 10/056 (20130101) H01M 10/0568 (20130101) H01M 10/0569 (20130101) H01M 50/116 (20210101) H01M 50/446 (20210101) H01M 2004/027 (20130101) H01M 2220/30 (20130101) H01M 2300/0037 (20130101) H01M 2300/0065 (20130101) H01M 2300/0091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220399696 | Chevalier et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Henry O. Everitt (Huntsville, Alabama); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); The United States of America as Represented by the Secretary of the Army (Huntsville, Alabama) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); The United States of America as Represented by the Secretary of the Army (Huntsville, Alabama) |
| INVENTOR(S) | Paul Chevalier (Cambridge, Massachusetts); Arman Amirzhan (Cambridge, Massachusetts); Marco Piccardo (Cambridge, Massachusetts); Fan Wang (Cambridge, Massachusetts); Steven Glen Johnson (Cambridge, Massachusetts); Henry O. Everitt (Huntsville, Alabama); Federico CAPASSO (Cambridge, Massachusetts) |
| ABSTRACT | Disclosed is a laser system including a first laser and a second laser. The first laser includes a laser cavity, and a gas phase molecular gain medium disposed in the laser cavity, the gain medium having an absorption band. The second laser is a solid state laser configured to be continuously tunable, with respect to an emission wavelength of the second laser, over the absorption band of the gain medium, and the second laser is tuned to pump rotational vibrational transitions in the gain medium to achieve a rotational population inversion. |
| FILED | Thursday, November 12, 2020 |
| APPL NO | 17/776547 |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/1312 (20130101) Original (OR) Class H01S 3/09415 (20130101) H01S 2302/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20220396378 | Hatsell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sierra Space Corporation (Broomfield, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Charles John Hatsell (Thornton, Colorado); Loren T. McDaniel (Denver, Colorado); Eric Charles Schleicher (Wheat Ridge, Colorado); Grant Robert Woods (Littleton, Colorado) |
| ABSTRACT | Methods, devices, and systems are described for a core of a space habitat. The core includes a plurality of internal beams extending a length of the core. The core also includes a plurality of end rings at a first end of the core and a second end of the core, the plurality of end rings spaced the length of the core. The core also includes an internal ring coupled to the internal beams between the first end and the second end. |
| FILED | Monday, April 11, 2022 |
| APPL NO | 17/718004 |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/48 (20130101) Original (OR) Class B64G 9/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220396379 | Woods et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sierra Space Corporation (Broomfield, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Grant Robert Woods (Littleton, Colorado); Jeffrey S. Hickerson (Erie, Colorado); Charles Ralph Sandy (Camden, Delaware) |
| ABSTRACT | Methods, devices, and systems are described for a bracket fixture for securing a load to a soft goods layer in a space habitat. The bracket fixture includes a base having a plurality of sides, the plurality of sides having a pin parallel to its respective side, and an aperture between the pin and the respective side. The bracket fixture further includes a protrusion extending from the base, the protrusion including a fixture element. |
| FILED | Monday, April 11, 2022 |
| APPL NO | 17/717989 |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/60 (20130101) Original (OR) Class B64G 2001/224 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220397531 | ANGEL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF SOUTH CAROLINA (COLUMBIA, South Carolina); LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (LIVERMORE, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | STANLEY MICHAEL ANGEL (COLUMBIA, South Carolina); JERRY CHANCE CARTER (LIVERMORE, California) |
| ABSTRACT | A hyperspectral imaging apparatus based on a monolithic or free space optical spatial heterodyne spectrometer (SHS) design, array detector, electromagnetic radiation source, and optical collection element is described. The apparatus enables the simultaneous acquisition of spatially isolated Fizeau fringe patterns, each having an encoded light product that is decoded to produce a spectral fingerprint of the interrogated object. Features specific to the SHS, such as a large entrance aperture, large acceptance angle, and no moving parts, enable a variety of optical collection schemes including lens arrays, solid-core and hollow core waveguides, and others. In one example, a microlens array (MLA) is configured with the hyperspectral imaging apparatus to simultaneously image many hundred spatially isolated Fizeau fringe patterns while interrogating an object using an electromagnetic radiation source. Each Fizeau fringe pattern recorded by the array detector is decoded to produce a full Raman or laser-induced breakdown spectroscopy (LIBS) spectrum. Compared to prior art, the hyperspectral imaging apparatus overcomes the primary limitations of needing to trade time resolution for both spectral and spatial data density because the imaging apparatus simultaneously acquires both spectral and special information. Based on the selection and configuration of diffraction gratings, the grating aperture size, Littrow wavelength (i.e., heterodyne wavelength), and optical collection configuration, the apparatus can be tailored to produced low or high spectral resolution with a spectral bandpass that covers a portion or the entire Raman spectral range (up to 4200 cm−1) and for LIBS as well. |
| FILED | Monday, November 11, 2019 |
| APPL NO | 17/772265 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) Original (OR) Class G01N 2201/0633 (20130101) G01N 2201/0635 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220399458 | Cui et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Peng Cui (Jinan, China PRC); Yuping Zeng (Newark, Delaware) |
| ASSIGNEE(S) | University of Delaware (Newark, Delaware) |
| INVENTOR(S) | Peng Cui (Jinan, China PRC); Yuping Zeng (Newark, Delaware) |
| ABSTRACT | A semiconductor device and fabricating method thereof is disclosed. The method comprises depositing epitaxial layers over a silicon substrate to form a semiconductor layer surface; forming at least one mesa portion on the semiconductor layer surface; depositing a metal stack on the semiconductor layer surface; subjecting the semiconductor layer surface to a rapid thermal annealing system for a two-step ohmic contact annealing in H2/N2 forming gas (FG) and then nitrogen; subjecting the semiconductor layer surface to an oxygen plasma treatment; and depositing a T-shaped metal gate on the semiconductor layer surface. A semiconductor device comprises a semiconductor layer surface having an epitaxial layer disposed over a silicon substrate; at least one mesa portion formed on the semiconductor layer surface; a metal stack, disposed on the semiconductor layer surface, and sequentially annealed in FG and nitrogen; and a T-shaped metal gate on the semiconductor layer surface. |
| FILED | Thursday, June 09, 2022 |
| APPL NO | 17/836487 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0254 (20130101) H01L 21/02271 (20130101) H01L 21/02293 (20130101) H01L 21/02458 (20130101) H01L 21/3245 (20130101) H01L 29/2003 (20130101) H01L 29/7786 (20130101) H01L 29/66462 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220399649 | Bray |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew G. Bray (Ellicott City, Maryland) |
| ABSTRACT | An antenna includes a waveguide defined by a gap between a backplane with radial support ribs and a facesheet, a teardrop-shaped feed pin at a center of the backplane, and a foam spacer between the backplane and facesheet. An outward facing side of the facesheet includes thermal paint. The facesheet includes pairs of through-hole slots for releasing portions of a wave of radiation in the waveguide to generate a transmit-beam or to receive the receive-beam to generate the wave of radiation. The pairs may be disposed as a spiral array about a center of the facesheet. Each of the pairs may include first and second slots. A length of the second slot is oriented approximately perpendicular to a length of the first slot. Dispositions of the slots are set by a computer process. The dispositions optimize a trade-off between transmit and receive gains. |
| FILED | Monday, March 28, 2022 |
| APPL NO | 17/705554 |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 9/0421 (20130101) Original (OR) Class H01Q 19/13 (20130101) H01Q 19/15 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220399800 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| INVENTOR(S) | Bo Liu (Vernon, Connecticut); Yongduk Lee (Vernon, Connecticut); Xin Wu (Glastonbury, Connecticut); Suman Dwari (East Hartford, Connecticut) |
| ABSTRACT | A power converter can include a first line, a second line, a capacitor line disposed between the first line and the second line, a first capacitor and a second capacitor connected to the capacitor line in series between the first line and the second line, a midpoint line connected to a midpoint between the first capacitor and the second capacitor, and a protection circuit disposed between the first capacitor and the second capacitor and configured to provide protection to one or more portions of the power converter. |
| FILED | Friday, June 11, 2021 |
| APPL NO | 17/345548 |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/32 (20130101) Original (OR) Class H02M 7/217 (20130101) H02M 7/537 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20220395477 | MOHAPATRA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Shyam S. MOHAPATRA (Lutz, Florida); Subhra MOHAPATRA (Lutz, Florida); Andrew Robert MCGILL (Tampa, Florida); Eleni MARKOUTSA (Tampa, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shyam S. MOHAPATRA (Lutz, Florida); Subhra MOHAPATRA (Lutz, Florida); Andrew Robert MCGILL (Tampa, Florida); Eleni MARKOUTSA (Tampa, Florida) |
| ABSTRACT | The present disclosure relates to compositions and uses thereof for preventing and treating respiratory syncytial vims (RSV) infection. In some aspects, disclosed herein is a method for preventing or treating respiratory syncytial vims (RSV) infection in a subject, comprising administering to the subject a therapeutically effective amount of a composition comprising a short-chain fatty acid. |
| FILED | Thursday, October 29, 2020 |
| APPL NO | 17/773257 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/19 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220395679 | Gutierrez |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jorge Antonio T. Gutierrez (Durham, North Carolina) |
| ABSTRACT | A system for improving blood flow through a circulatory system of a patient is disclosed. The patient can have a wrist. The circulatory system can have a radial artery, an ulnar artery, and a descending aorta. The system can comprise at least one inflatable bladder that is configured to be received into the descending aorta of the patient. A pump can be configured to cyclically pump a fluid into the at least one inflatable bladder to inflate the at least one inflatable bladder. A conduit can be positioned between and in fluid communication with the at least one inflatable bladder and the pump. The conduit can be configured to communicate the fluid between the pump and the at least one inflatable bladder. The conduit can have a length of at least 110 cm. |
| FILED | Friday, June 10, 2022 |
| APPL NO | 17/837556 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 60/139 (20210101) A61M 60/295 (20210101) Original (OR) Class A61M 60/857 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220398458 | MOHAPATRA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shyam S. MOHAPATRA (Lutz, Florida); Subhra MOHAPATRA (Lutz, Florida); Anmol WARMAN (Lutz, Florida) |
| ABSTRACT | Disclosed are various embodiments of systems and methods of deep learning for colorectal polyp screening and providing a prediction of neoplasticity of a polyp. A video of a colonoscopy procedure can be captured. Frames from the video or images associated with the colonoscopy procedure can be extracted. A model for classifying objects that appear in the frames or the images can be obtained. A classification can be determined for a polyp that appears in at least one of the frames or images based on applying the frames or images to an input layer of the model. |
| FILED | Friday, November 13, 2020 |
| APPL NO | 17/776944 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class G06N 3/0445 (20130101) G06N 3/0454 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20220396043 | JETHMALANI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Novol, Inc. (San Leandro, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jagdish JETHMALANI (San Leandro, California); Sanjiban CHAKRABORTY (San Leandro, California); Monica BHATIA (San Leandro, California) |
| ABSTRACT | Provided herein are methods of molding thermoplastic polymers into optical elements. The optical elements in the form of cylindrical discs, semi-finished lens blanks or finished lenses are compression molded at high temperature typically above thermoplastic polymers softening temperature and under high pressure. The semi-finished lens blanks and finished lenses are molded using front and back glass molds inside a mold assembly which reshapes the cylindrical discs that are either previously molded or cut out from thick slab. Also provided are methods for producing single vision and progressive addition lens prescriptions. |
| FILED | Monday, August 22, 2022 |
| APPL NO | 17/893017 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 51/30 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/0049 (20130101) Original (OR) Class B29D 11/00413 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2033/12 (20130101) Optical Elements, Systems, or Apparatus G02B 1/041 (20130101) Spectacles; Sunglasses or Goggles Insofar as They Have the Same Features as Spectacles; Contact Lenses G02C 7/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220397457 | KIM et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | MOON S. KIM (ASHTON, Maryland); DIANE E. CHAN (ODENTON, Maryland); JIANWEI QIN (ELLICOTT CITY, Maryland); INSUCK BAEK (BURTONSVILLE, Maryland) |
| ABSTRACT | A line scan imaging system scans a targeted inspection area and gathers reflectance and fluorescence data. The inspection system comprises at least a rotatable/pivotable mirror-faced triangular prism, a line illumination source, and a line scan hyperspectral camera. The prism has a mirrored camera face and a mirrored illumination face. In operation, as the prism rotates, the camera instantaneous field of view (IFOV) and the projected illumination line converge at a nadir convergence scan line so that the hyperspectral camera receives line scan data from the nadir convergence scan line as the nadir convergence scan line traverses an inspection area. |
| FILED | Thursday, June 09, 2022 |
| APPL NO | 17/836310 |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/021 (20130101) G01J 3/024 (20130101) G01J 3/0237 (20130101) G01J 3/2823 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 20220397664 | Pedross-Engel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Andreas Pedross-Engel (Seattle, Washington); Daniel Arnitz (Seattle, Washington); Matthew S. Reynolds (Seattle, Washington) |
| ABSTRACT | Examples of active millimeter-wave imaging systems are described which may utilize modulation schemes to provide illumination signals. The use of modulation techniques may allow for the use of direct-conversion receivers while retaining an ability to separate desired received signal from self-jamming and/or DC offset signal(s) generated by the direct-conversion receivers. In some examples, modulation schemes include the use of balanced orthogonal codes which may support MIMO or massive MIMO imaging systems. |
| FILED | Friday, August 19, 2022 |
| APPL NO | 17/821151 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/89 (20130101) Original (OR) Class G01S 13/325 (20130101) G01S 13/887 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/20 (20130101) Pictorial Communication, e.g Television H04N 5/2256 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Geospatial Intelligence Agency (NGA)
| US 20220398709 | Gudavalli et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mayachitra, Inc. (Santa Barbara, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chandrakanth Gudavalli (Santa Barbara, California); Michael Gene Goebel (Santa Barbara, California); Tejaswi Nanjundaswamy (Mountain View, California); Lakshmanan Nataraj (Chennai, India); Shivkumar Chandrasekaran (Santa Barbara, California); Bangalore S. Manjunath (Santa Barbara, California) |
| ABSTRACT | Systems and methods herein describe a metadata verification system that is configured to access a digital satellite image, generate a first discrete Fourier transform (DFT) pattern based on an ortho-rectified digital satellite image, generate a second DFT pattern based on rational polynomial coefficient (RPC) data of the digital satellite image, compare the first DFT pattern to the second DFT pattern, generate a score based on the comparison, and generate a determination of whether the digital satellite image has been manipulated based on the score. |
| FILED | Wednesday, June 09, 2021 |
| APPL NO | 17/342992 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/0002 (20130101) Original (OR) Class G06T 2200/24 (20130101) G06T 2207/10032 (20130101) G06T 2207/20056 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Reconnaissance Office (NRO)
| US 20220397664 | Pedross-Engel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Andreas Pedross-Engel (Seattle, Washington); Daniel Arnitz (Seattle, Washington); Matthew S. Reynolds (Seattle, Washington) |
| ABSTRACT | Examples of active millimeter-wave imaging systems are described which may utilize modulation schemes to provide illumination signals. The use of modulation techniques may allow for the use of direct-conversion receivers while retaining an ability to separate desired received signal from self-jamming and/or DC offset signal(s) generated by the direct-conversion receivers. In some examples, modulation schemes include the use of balanced orthogonal codes which may support MIMO or massive MIMO imaging systems. |
| FILED | Friday, August 19, 2022 |
| APPL NO | 17/821151 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/89 (20130101) Original (OR) Class G01S 13/325 (20130101) G01S 13/887 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/20 (20130101) Pictorial Communication, e.g Television H04N 5/2256 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 20220398820 | ABD-ALMAGEED et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Wael ABD-ALMAGEED (Woodstock, Maryland); Leonidas SPINOULAS (Los Angeles, California); Mohamed E. HUSSEIN (Falls Church, Virginia); David GEISSBUHLER (Martigny, Switzerland); Sebastien MARCEL (Martigny, Switzerland) |
| ABSTRACT | A general framework for building a biometrics system capable of capturing multispectral data from a series of sensors synchronized with active illumination sources is provided. The framework unifies the system design for different biometric modalities and its realization on face, finger and iris data is described in detail. To the best of our knowledge, the presented design is the first to employ such a diverse set of electromagnetic spectrum bands, ranging from visible to long-wave-infrared wavelengths, and is capable of acquiring large volumes of data in seconds. Having performed a series of data collections, we run a comprehensive analysis on the captured data using a deep-learning classifier for presentation attack detection. The invention follows a data-centric approach attempting to highlight the strengths and weaknesses of each spectral band at distinguishing live from fake samples. |
| FILED | Monday, June 13, 2022 |
| APPL NO | 17/838372 |
| CURRENT CPC | Image or Video Recognition or Understanding G06V 10/82 (20220101) G06V 10/141 (20220101) G06V 10/143 (20220101) Original (OR) Class G06V 10/764 (20220101) G06V 40/45 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20220396043 | JETHMALANI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Novol, Inc. (San Leandro, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jagdish JETHMALANI (San Leandro, California); Sanjiban CHAKRABORTY (San Leandro, California); Monica BHATIA (San Leandro, California) |
| ABSTRACT | Provided herein are methods of molding thermoplastic polymers into optical elements. The optical elements in the form of cylindrical discs, semi-finished lens blanks or finished lenses are compression molded at high temperature typically above thermoplastic polymers softening temperature and under high pressure. The semi-finished lens blanks and finished lenses are molded using front and back glass molds inside a mold assembly which reshapes the cylindrical discs that are either previously molded or cut out from thick slab. Also provided are methods for producing single vision and progressive addition lens prescriptions. |
| FILED | Monday, August 22, 2022 |
| APPL NO | 17/893017 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 51/30 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/0049 (20130101) Original (OR) Class B29D 11/00413 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2033/12 (20130101) Optical Elements, Systems, or Apparatus G02B 1/041 (20130101) Spectacles; Sunglasses or Goggles Insofar as They Have the Same Features as Spectacles; Contact Lenses G02C 7/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 20220396601 | ZHANG |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Li ZHANG (Plano, Texas) |
| ABSTRACT | The disclosure relates to engineered heme sequestering peptides and their use in treating cancer and inhibiting microbial infections and colonization. |
| FILED | Friday, May 13, 2022 |
| APPL NO | 17/743835 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/164 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/10 (20180101) A61P 35/00 (20180101) Peptides C07K 14/24 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, December 15, 2022.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-applications-20221215.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page