FedInvent™ Patents
Patent Details for Tuesday, February 08, 2022
This page was updated on Thursday, February 10, 2022 at 11:05 PM GMT
Department of Health and Human Services (HHS)
| US 11240996 | Chernoff et al. |
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| FUNDED BY |
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| APPLICANT(S) | Institute For Cancer Research (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Institute For Cancer Research (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Jonathan Chernoff (Philadelphia, Pennsylvania); Hoi Yee Chow (Philadelphia, Pennsylvania) |
| ABSTRACT | Mice comprising a transgene encoding a peptide (iBox) inhibitor of Group B p21-activated kinase are provided. Also provided are cells, tissue, and organs obtained from such transgenic mice. Also provided are methods for producing mice comprising an iBox-encoding transgene. |
| FILED | Wednesday, August 23, 2017 |
| APPL NO | 15/683948 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) Original (OR) Class A01K 67/0278 (20130101) A01K 2217/052 (20130101) A01K 2227/105 (20130101) A01K 2267/0331 (20130101) Peptides C07K 14/4703 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/14 (20130101) C12N 9/1088 (20130101) Enzymes C12Y 205/01018 (20130101) C12Y 306/05002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241155 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Zhongping Chen (Irvine, California); Yan Li (Irvine, California) |
| ABSTRACT | An OCT system with a swept light source centered around 1.7 μm for identifying atherosclerotic plaque and visualization of large lipid pool is provided. Advantages for using the 1.7 μm swept source laser include higher contrast between lipid and normal tissue and deeper penetration of the optical signals from the 1.7 μm swept source laser into the tissue. With deeper penetration into the tissue, more structural information from deep within the tissue is obtained. The present invention also features multimodality imaging systems that integrate additional imaging systems into the OCT system at 1.7 μm. As an example, an integrated 1.3 μm and 1.7 μm OCT system is provided which simultaneously generates OCT images using both the OCT systems which are used to characterize and differentiate the types of tissue. |
| FILED | Wednesday, January 24, 2018 |
| APPL NO | 15/878762 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0035 (20130101) Original (OR) Class A61B 5/0066 (20130101) A61B 5/0071 (20130101) A61B 5/0075 (20130101) A61B 5/0095 (20130101) A61B 5/02028 (20130101) A61B 8/12 (20130101) A61B 8/485 (20130101) A61B 8/5261 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241163 | Sutton et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Bradley P. Sutton (Savoy, Illinois); Alexander M. Cerjanic (Champaign, Illinois); Luisa Ciobanu (Gif-sur-Yvette, France); Denis LeBihan (Gif-sur-Yvette, France); Jing-Rebecca Li (Palaiseau, France); Gabrielle Fournet (Gif-sur-Yvette, France) |
| ABSTRACT | Aspects of the subject disclosure may include, for example, obtaining first magnetic resonance imaging (MRI) data of a subject, wherein the first MRI data is obtained during a first scan of a subject, wherein the first scan has a first diffusion sampling time, and wherein the first diffusion sampling time is selected in order to facilitate use of the first MRI data to determine a first Intravoxel Incoherent Motion (IVIM) effective diffusion coefficient in a Stationary Random Flow (SRF) regime; obtaining second MRI data of the subject, wherein the second MRI data is obtained during a second scan of the subject, wherein the second scan has a second diffusion sampling time, wherein the second diffusion sampling time is longer than the first diffusion sampling time, and wherein the second diffusion sampling time is selected in order to facilitate use of the second MRI data to determine a second IVIM effective diffusion coefficient in a pseudodiffusion regime; determining a blood velocity value based upon the first MRI data; and determining a segment length value based upon the second MRI data. Additional embodiments are disclosed. |
| FILED | Thursday, June 07, 2018 |
| APPL NO | 16/002958 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Original (OR) Class A61B 5/0263 (20130101) A61B 5/489 (20130101) A61B 5/4088 (20130101) A61B 2576/026 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/56341 (20130101) G01R 33/56366 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/10016 (20130101) G06T 2207/10088 (20130101) G06T 2207/20104 (20130101) G06T 2207/30101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241170 | Kim et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland); BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan); Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland); Board of Trustees of Michigan State University (East Lansing, Michigan); Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Chang-Sei Kim (North Potomac, Maryland); Stephanie Lind-Ober Martin (College Park, Maryland); Jin-Oh Hahn (Rockville, Maryland); Ramakrishna Mukkamala (Okemos, Michigan); Omer T. Inan (Marietta, Georgia) |
| ABSTRACT | A method and apparatus for monitoring arterial properties, including systolic and diastolic pressure levels, of a subject is provided, in which a hardware processor receives and analyzes ballistocardiogram (BCG) data of the subject. A non-transient computer readable medium, accessible by the hardware processor, contains instructions that, when executed by the hardware processor, identify features of the BCG waveform and determine the arterial properties therefrom. For example, a diastolic pressure level may be determined from a time interval between the ‘I’ and ‘J’ peaks of the waveform and a systolic pressure level determined from the amplitude difference between the ‘J’ and ‘K’ peaks of the waveform in combination with the ‘I-J’ time interval or amplitude difference. A physical mechanism for the BCG data is disclosed that enables other arterial properties of the subject to be determined from the BCG data alone or from the BCG data in combination with other measurements. |
| FILED | Friday, April 06, 2018 |
| APPL NO | 15/946889 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1102 (20130101) Original (OR) Class A61B 5/02108 (20130101) A61B 5/02438 (20130101) A61B 5/7253 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241189 | Smiley et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia); The MetroHealth System (Cleveland, Ohio) |
| ASSIGNEE(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio); THE METROHEALTH SYSTEM (Cleveland, Ohio); THE U.S. GOV'T AS REPRESENTED BY THE DEPT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Aref Smiley (Cleveland, Ohio); Dennis Bourbeau (Cleveland Hts., Ohio); Margot S. Damaser (Cleveland Hts., Ohio); Steve Majerus (University Hts., Ohio); Massarat Zutshi (Cleveland Hts., Ohio); Ian Mcadams (Cleveland Hts., Ohio) |
| ABSTRACT | A sensing device can be placed within the colon to study bowel function. The sensing device can include a flexible printed circuit board that includes at least one senor configured to record data related to bowel activity from a patient's colon; and a wireless transmitter configured to send the data from the patient's colon to an external device. The sensing device can also include at least one mucosal clip configured to fix the sensor board to a wall of the patient's colon for a measurement period. The flexible printed circuit board and/or the at least one mucosal clip are configured to be passed from the patient's colon after the measurement period through normal defecation. |
| FILED | Wednesday, July 17, 2019 |
| APPL NO | 16/514982 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/07 (20130101) A61B 5/0022 (20130101) A61B 5/0031 (20130101) A61B 5/4255 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241190 | Viswanath et al. |
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| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Satish Viswanath (Beachwood, Ohio); Iulia Barbur (Akron, Ohio) |
| ABSTRACT | Embodiments discussed herein facilitate predicting response to therapy in Crohn's disease. A first set of embodiments discussed herein relates to accessing a radiological image of a region of tissue demonstrating Crohn's disease associated with a patient; defining a mesenteric fat region by segmenting mesenteric fat represented in the radiological image; extracting a set of radiomic features from the mesenteric fat region; providing the set of radiomic features to a machine learning classifier configured to compute a probability of response to therapy in Crohn's disease based, at least in part, on the set of radiomic features; receiving, from the machine learning classifier, a probability that the region of tissue will respond to therapy; generating a classification of the patient as a responder or non-responder based, at least in part, on the probability; and displaying the classification. |
| FILED | Monday, September 16, 2019 |
| APPL NO | 16/571454 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0037 (20130101) A61B 5/4255 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6231 (20130101) Computer Systems Based on Specific Computational Models G06N 7/046 (20130101) G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) G06T 2207/10088 (20130101) G06T 2207/30028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241207 | Wen |
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| FUNDED BY |
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| APPLICANT(S) | The USA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Han Wen (Bethesda, Maryland) |
| ABSTRACT | This disclosure generally relates to systems, methods, and devices for performing high-resolution computer tomography (CT) scans providing highly detailed images of particular regions using whole body clinical CT scanners while maintaining high imaging speeds and low dose levels. In particular, the disclosed systems use flat panel detectors in conjunction with common CT detectors to quickly produce high-resolution CT images. |
| FILED | Tuesday, August 14, 2018 |
| APPL NO | 16/639469 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/032 (20130101) A61B 6/482 (20130101) Original (OR) Class A61B 6/547 (20130101) A61B 6/585 (20130101) A61B 6/4208 (20130101) A61B 6/5258 (20130101) Image Data Processing or Generation, in General G06T 7/10 (20170101) G06T 11/005 (20130101) G06T 2207/10081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241380 | Freeman et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | William Freeman (Del Mar, California); Michael J. Sailor (La Jolla, California); Lingyun Cheng (San Diego, California); Frederique Cunin (Montpellier, France); Emily Anglin (San Diego, California); Yang Yang Li (Hong Kong, China Hong Kong) |
| ABSTRACT | A minimally invasive controlled drug delivery system for delivering a particular drug or drugs to a particular location of the eye, the system including a porous film template having pores configured and dimensioned to at least partially receive at least one drug therein, and wherein the template is dimensioned to be delivered into or onto the eye. |
| FILED | Monday, November 06, 2017 |
| APPL NO | 15/804856 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/0017 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) Original (OR) Class A61K 9/0051 (20130101) A61K 9/1611 (20130101) A61K 9/7007 (20130101) A61K 31/573 (20130101) A61K 47/24 (20130101) A61K 47/26 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241394 | Zhang et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Liangfang Zhang (San Diego, California); Che-Ming Jack Hu (Novato, California); Ronnie H. Fang (San Diego, California); Brian T. Luk (San Diego, California); Kuei-Chun Wang (San Diego, California); Shu Chien (La Jolla, California) |
| ABSTRACT | The present invention relates to prevention and/or treatment of diseases or disorders associated with a damaged or leaky vasculature in a subject. The present invention provides for methods, combinations and pharmaceutical compositions for preventing and/or treating a disease or disorder associated with a damaged or leaky vasculature in a subject, using, inter alia, an effective amount of a nanoparticle comprising an inner core comprising a non-cellular material, an outer surface comprising a cellular membrane derived from a platelet; and optionally an agent for preventing, treating, diagnosing, or prognosing the disease or disorder and/or monitoring prevention or treatment of the disease or disorder. Exemplary diseases or disorders include hemorrhage (bleeding), cardiovascular diseases or disorders, diseases or disorders associated with narrowing of a blood vessel, tumors or cancers. |
| FILED | Tuesday, June 07, 2016 |
| APPL NO | 15/737566 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5153 (20130101) A61K 9/5169 (20130101) A61K 9/5176 (20130101) Original (OR) Class A61K 31/337 (20130101) A61K 47/6901 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/04 (20180101) A61P 9/00 (20180101) A61P 35/00 (20180101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 30/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241421 | Bushweller et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia) |
| ASSIGNEE(S) | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia) |
| INVENTOR(S) | John H. Bushweller (Crozet, Virginia); Anuradha Illendula (Crozet, Virginia) |
| ABSTRACT | This invention relates to methods and compositions for treatment of inv(16) leukemia and particularly to treatment of acute myeloid leukemia. Disclosed is a method of treating inv(16) leukemia comprising the step of administering to a subject in need thereof a therapeutically effective combination of a) a compound of the formula (1) and b) a chemotherapeutic agent selected from the group consisting of pirarubicin, aclarubicin, mitoxantrone, doxorubicin, daunorubicin, idarubicin, epirubicin, cytarabine, pharmaceutically acceptable salts and mixtures thereof. The therapeutically effective combination synergistically inhibits proliferation of inv(16) leukemia cells. This invention also relates to pharmaceutical compositions comprising a therapeutically effective combination of the compound of formula (1) and the chemotherapeutic agent and a pharmaceutically acceptable excipient. |
| FILED | Thursday, July 27, 2017 |
| APPL NO | 16/318041 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 31/4439 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241434 | Strittmatter |
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| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale Uninversity (New Haven, Connecticut) |
| INVENTOR(S) | Stephen M. Strittmatter (Guilford, Connecticut) |
| ABSTRACT | The present invention provides compositions and methods for treating and preventing an Aβ-modulated disease and/or a Tauopathy. In certain embodiments, the invention provides an inhibitor of Fyn tyrosine kinase, and methods of using the same. In certain embodiments, the inhibitor of the invention inhibits Aβ oligomer induced signaling and reduces or halts the progression of Alzheimer's Disease. |
| FILED | Monday, March 16, 2020 |
| APPL NO | 16/820060 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/517 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241435 | Wein et al. |
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| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts); The Broad Institute, Inc. (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts); The Broad Institute, Inc. (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Marc Wein (Boston, Massachusetts); Henry Kronenberg (Boston, Massachusetts); Thomas Sundberg (Boston, Massachusetts); Ramnik Xavier (Brookline, Massachusetts); Nathanael S. Gray (Stanford, California); Yanke Liang (Belmont, Massachusetts); Hwan Geun Choi (Chestnut Hill, Massachusetts); Alykhan Shamji (Somerville, Massachusetts) |
| ABSTRACT | The present disclosure provides methods of treating and/or preventing osteoporosis using salt-inducible kinase (SIK) inhibitors. Also provided are methods of using SIK inhibitors for increasing the function of osteocytes, increasing the number of osteoblasts, increasing the activity of osteoblasts, inhibiting the resorption of a bone, decreasing the number of osteoclasts, inhibiting the activity of osteoclasts, increasing the mass of a bone, down-regulating the expression of the gene SOST, and/or inhibiting the activity of sclerostin. The SIK inhibitors may be combined with Src inhibitors or CSF I R inhibitors. Exemplary SIK inhibitors include the compounds of the formula: (I), (II), (III), (IV), (V) or (VI). |
| FILED | Saturday, September 16, 2017 |
| APPL NO | 16/333546 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241436 | He et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois); The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland); University of Kansas (Lawrence, Kansas) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois); The United States of Americans represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); University of Kansas (Lawrence, Kansas) |
| INVENTOR(S) | Congcong He (Chicago, Illinois); Sui Huang (Chicago, Illinois); Chen Wang (Chicago, Illinois); Altea Rocchi (Evanston, Illinois); Juan Jose Marugan (Gaithersburg, Maryland); Marc Ferrer (Potomac, Maryland); Samarjit Patnaik (Gaithersburg, Maryland); Yuchi Chen (Rockville, Maryland); Kevin Frankowski (Pittsboro, North Carolina); Frank J. Schoenen (Lawrence, Kansas) |
| ABSTRACT | The invention provides a compound of formula (I): wherein R1, R2, R3, and R4 are as defined herein, ginsenoside Rg2 of structure (II): or a combination thereof, for use in treating or preventing a condition responsive to the induction of autophagy in a brain of a mammal in need thereof. |
| FILED | Thursday, January 25, 2018 |
| APPL NO | 16/480885 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) Original (OR) Class A61K 31/704 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241454 | Pelus et al. |
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| FUNDED BY |
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| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Louis M. Pelus (Indianapolis, Indiana); Jonathan Hoggatt (Somerville, Massachusetts); Pratibha Singh (Indianapolis, Indiana) |
| ABSTRACT | This disclosure is directed to the methods of enhancing hematopoietic stem cells (HSPC) and progenitor cell (HSPC) engraftment procedure. Treatment in vivo of a HSPC donor with compounds that reduce PGE2 biosynthesis or PGE2 receptor antagonists alone, or in combination with other hematopoietic mobilization agents such as AMD3100 and G-CSF, increases the circulation of available HSPCs. Compounds that reduce the cellular synthesis of PGE2 include non-steroidal anti-inflammatory compounds such as indomethacin. Treatment ex vivo of HSPC with an effective amount of PGE2 or at least one of its derivatives such as 16,16-dimethyl prostaglandin E2 (dmPGE2), promotes HSPC engraftment. Similar methods may also be used to increase viral-mediated gene transduction efficacy into HSPC. |
| FILED | Thursday, May 11, 2017 |
| APPL NO | 15/592375 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/395 (20130101) A61K 31/405 (20130101) A61K 31/4035 (20130101) A61K 31/4196 (20130101) A61K 31/5415 (20130101) A61K 35/14 (20130101) Original (OR) Class A61K 35/28 (20130101) A61K 35/50 (20130101) A61K 35/51 (20130101) A61K 38/193 (20130101) A61K 2035/124 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/16 (20130101) C12N 5/0647 (20130101) C12N 9/0083 (20130101) C12N 15/63 (20130101) C12N 15/86 (20130101) C12N 2501/02 (20130101) Enzymes C12Y 114/99001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241466 | Archibong et al. |
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| FUNDED BY |
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| APPLICANT(S) | Meharry Medical College (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anthony E. Archibong (Antioch, Tennessee); G. William Bates (Brentwood, Tennessee); Elochukwu J. Ezekakpu (Nashville, Tennessee); Lorin W. Simon (Antioch, Tennessee); James E. K. Hildreth (Nashville, Tennessee) |
| ABSTRACT | Artificial cervical fluid is disclosed that contains a mucilaginous extract from the okra plant. The mucilaginous extract can be produced using a hot aqueous extractant or cold extraction process followed by separation of larger particles from the extract. The extract finds many uses, for example as a sperm storage medium, a sperm freezing medium, a sexual lubricant, an artificial insemination medium, and an in vitro fertilization medium. |
| FILED | Wednesday, March 06, 2019 |
| APPL NO | 16/294839 |
| ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/021 (20130101) A01N 1/0221 (20130101) Diagnosis; Surgery; Identification A61B 17/43 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 6/04 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0034 (20130101) A61K 36/185 (20130101) Original (OR) Class A61K 2236/33 (20130101) A61K 2236/39 (20130101) A61K 2236/53 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 15/08 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241480 | Newberry et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rodney Newberry (St. Louis, Missouri); Kathryn Knoop (St. Louis, Missouri); Keely McDonald (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Rodney Newberry (St. Louis, Missouri); Kathryn Knoop (St. Louis, Missouri); Keely McDonald (St. Louis, Missouri) |
| ABSTRACT | Among the various aspects of the present disclosure is the provision of compositions and methods for modulation of dietary and microbial exposure. The present disclosure provides for compositions and methods for treating, preventing, or reducing the likelihood of development of an allergic disorder, necrotizing enterocolitis, sepsis, or an inflammatory disease, disorder, or condition in a subject including administering an effective amount of a composition comprising an EGFR ligand. |
| FILED | Friday, January 26, 2018 |
| APPL NO | 15/880658 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0095 (20130101) A61K 31/728 (20130101) A61K 38/1808 (20130101) Original (OR) Class A61K 38/1841 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/08 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241487 | Daniell et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
| INVENTOR(S) | Henry Daniell (Media, Pennsylvania); Qiuhong Li (Gainesville, Florida); Mohan K. Raizada (Alachua, Florida) |
| ABSTRACT | Emerging evidence indicates that diminished activity of the vasoprotective axis of the renin-angiotensin system, constituting angiotensin converting enzyme2 (ACE2) and its enzymatic product, angiotensin-(1-7) [Ang-(1-7)] contribute to pulmonary hypertension (PH). However, clinical success for long-term delivery of ACE2 or Ang-(1-7) would require stability and ease of administration to increase patient compliance. Chloroplast expression of therapeutic proteins enables their bioencapsulation within plant cells to protect from acids and gastric enzymes; fusion to a transmucosal carrier facilitates effective systemic absorption. Oral feeding of rats with bioencapsulated ACE2 or Ang-(1-7) attenuated monocrotaline (MCT)-induced increase in right ventricular systolic pressure, decreased pulmonary vessel wall thickness and improved right heart function in both prevention and reversal protocols. Furthermore, combination of ACE2 and Ang-(1-7) augmented the beneficial effects against cardio-pulmonary pathophysiology induced by MCT administration. Experiments have also been performed which indicate that this approach is also suitable for the treatment or inhibition of experimental uveitis and autoimmune uveoretinitis These studies provide proof-of-concept for a novel low-cost oral ACE2 or Ang-(1-7) delivery system using transplastomic technology for pulmonary and ocular disease therapeutics. |
| FILED | Monday, August 24, 2020 |
| APPL NO | 17/001667 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/19 (20130101) A61K 9/0053 (20130101) A61K 9/1664 (20130101) A61K 9/5063 (20130101) A61K 36/23 (20130101) A61K 36/28 (20130101) A61K 36/31 (20130101) A61K 38/22 (20130101) A61K 38/164 (20130101) A61K 38/4813 (20130101) Original (OR) Class A61K 47/65 (20170801) A61K 47/6415 (20170801) Peptides C07K 14/28 (20130101) C07K 2319/55 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/485 (20130101) C12N 15/8214 (20130101) C12N 15/8257 (20130101) Enzymes C12Y 304/15001 (20130101) C12Y 304/17023 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241490 | Weissman et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Drew Weissman (Wynnewood, Pennsylvania); Norbert Pardi (Philadelphia, Pennsylvania); Michael Hogan (Philadelphia, Pennsylvania) |
| ABSTRACT | The present invention relates to compositions and methods for inducing an adaptive immune response against Zika virus (ZIKV) in a subject. In certain embodiments, the present invention provides a composition comprising a nucleoside-modified nucleic acid molecule encoding a ZIKV antigen, adjuvant, or a combination thereof. For example, in certain embodiments, the composition comprises a vaccine comprising a nucleoside-modified nucleic acid molecule encoding a ZIKV antigen, adjuvant, or a combination thereof. |
| FILED | Thursday, January 11, 2018 |
| APPL NO | 16/477258 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5123 (20130101) A61K 39/12 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/55 (20130101) A61K 2039/545 (20130101) A61K 2039/55511 (20130101) A61K 2039/55555 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2770/24134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241491 | Baric et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Ralph Baric (Haw River, North Carolina); Matthew Begley (Durham, North Carolina); Douglas Widman (Newton Center, Massachusetts); Aravinda Desilva (Chapel Hill, North Carolina); Usha Nivarthi (Morrisville, North Carolina); Boyd Yount (Hillsborough, North Carolina); Ellen Young (Hillsborough, North Carolina) |
| ABSTRACT | The present invention provides compositions and methods of use comprising a chimeric dengue virus E glycoprotein comprising a dengue virus E glycoprotein backbone, which comprises amino acid substitutions that introduce a dengue virus E glycoprotein epitope from a dengue virus serotype that is different from the dengue virus serotype of the dengue virus E glycoprotein backbone. |
| FILED | Wednesday, May 23, 2018 |
| APPL NO | 16/615350 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/70 (20130101) A61K 2039/575 (20130101) A61K 2039/5254 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/24122 (20130101) C12N 2770/24123 (20130101) C12N 2770/24134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241492 | Kawaoka et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
| INVENTOR(S) | Yoshihiro Kawaoka (Middleton, Wisconsin); Yuri Furusawa (Tokyo, Japan) |
| ABSTRACT | The disclosure provides for an isolated recombinant influenza virus having at least one of: a PB2 viral segment encoding PB2 with residue at position 540 that is not asparagine or a residue at position 712 that is not glutamic acid, a PA viral segment encoding PA with a residue at position 180 that is not glutamine or a residue at position 200 that is not threonine, or a PB1 viral segment encoding PB1 with a residue at position 149 that is not valine, a residue at position 684 that is not glutamic acid or a residue at position 685 that is not aspartic acid, or any combination thereof, and methods of making and using the virus. |
| FILED | Wednesday, January 22, 2020 |
| APPL NO | 16/749910 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/145 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/16 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241504 | Jayasuriya et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of Toledo (Toledo, Ohio) |
| ASSIGNEE(S) | The University of Toledo (Toledo, Ohio) |
| INVENTOR(S) | Ambalangodage C. Jayasuriya (Toledo, Ohio); Bipin Gaihre (Toledo, Ohio) |
| ABSTRACT | Compositions for delivering one or more active substances, or for repairing a bone, and methods of making and using the same, are described. |
| FILED | Tuesday, July 21, 2020 |
| APPL NO | 16/934474 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1875 (20130101) A61K 47/32 (20130101) A61K 47/34 (20130101) A61K 47/6903 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241575 | Bijanki et al. |
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| FUNDED BY |
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| APPLICANT(S) | Jon Timothy Willie (Atlanta, Georgia) |
| ASSIGNEE(S) | Kelly C.R. Bijanki (Houston, Texas); Jon T. Willie (St. Louis, Missouri) |
| INVENTOR(S) | Kelly Cathryn Rowe Bijanki (Decatur, Georgia); Cory Inman (Decatur, Georgia); Nigel Pedersen (Decatur, Georgia); Jon Timothy Willie (Atlanta, Georgia) |
| ABSTRACT | A method of stimulating a patient's brain comprising delivering an electrical stimulation to at least one electrode causing stimulation of a person's anterior cingulum bundle, or especially causing stimulation of a person's dorsal portion of an anterior cingulum bundle resulting in emotional change(s) in a patient comprising one or more of the following: anxiolysis, mirth, analgesia, improved affective tone, enhanced cognitive focus, increased well-being, engagement, or optimism. Further embodiments contemplate an apparatus. Further embodiments contemplate two implanted electrodes within the dorsal portion of the anterior cingulum bundle spaced between about 5 mm and 8 mm apart, having electrical stimulation parameters of between about 1.0 mA and about 3.5 mA, between about 100 Hz to about 150 Hz, and having a pulse width of between about 100 microseconds to about 200 microseconds. |
| FILED | Tuesday, September 04, 2018 |
| APPL NO | 16/121599 |
| ART UNIT | 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0531 (20130101) Original (OR) Class A61N 1/36071 (20130101) A61N 1/36096 (20130101) A61N 1/36132 (20130101) A61N 1/36135 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241576 | Hansen et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
| INVENTOR(S) | Marlan R. Hansen (Solon, Iowa); Christopher Kaufmann (Coralville, Iowa) |
| ABSTRACT | The present embodiment is an implantable device capable of controlling cochlear implant electrode insertion and positioning. The embodiment uses an implanted mechanical positioning unit to advance position and monitor an electrode array. The device can be controlled via an external controller to reposition or advance an electrode array at any point after implantation with no surgical re-intervention. A cochlear implant electrode array whose position can be advanced and modified over time to best fit a patient's evolving hearing pattern would improve functional outcomes and significantly expand the candidacy range for cochlear implantation to include patients with substantial residual hearing. |
| FILED | Friday, June 24, 2016 |
| APPL NO | 15/759643 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/3468 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0541 (20130101) Original (OR) Class A61N 1/36038 (20170801) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/09 (20130101) Transmission H04B 5/0037 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241579 | Ardell et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Jeffrey L. Ardell (Oakland, California); Kalyanam Shivkumar (Los Angeles, California) |
| ABSTRACT | The present invention provides systems and methods for monitoring cardiac autonomic nervous system activity and modulating parasympathetic control of cardiac function. |
| FILED | Friday, April 21, 2017 |
| APPL NO | 16/094594 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0551 (20130101) A61N 1/36062 (20170801) A61N 1/36114 (20130101) Original (OR) Class A61N 1/36117 (20130101) A61N 1/36139 (20130101) A61N 1/36171 (20130101) A61N 1/36507 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241586 | Tsai et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Li-Huei Tsai (Cambridge, Massachusetts); Anthony James Martorell (Cambridge, Massachusetts); Ho-Jun Suk (Cambridge, Massachusetts); Ed Boyden (Chestnut Hill, Massachusetts) |
| ABSTRACT | Devices, systems, and methods for a treating dementia or Alzheimer's disease in a subject in need thereof. In one example, combined auditory and visual stimuli having a frequency of about 20 Hz to about 60 Hz, and more specifically about 40 Hz, are non-invasively delivered to the subject to induce synchronized gamma oscillations in at least one brain region of the subject. In particular, pursuant to various treatment and exposure protocols, combined auditory and visual stimulation (as opposed to auditory or visual stimulation alone) promotes a microglia response in the medial prefrontal cortex (mPFC). More generally, combined auditory and visual stimulation induces an extended microglia clustering response in the auditory cortex, the visual cortex, and the mPFC. |
| FILED | Wednesday, September 19, 2018 |
| APPL NO | 16/135938 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 2021/0022 (20130101) A61M 2021/0027 (20130101) A61M 2210/0693 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 5/0618 (20130101) Original (OR) Class A61N 5/0622 (20130101) A61N 2005/063 (20130101) A61N 2005/0626 (20130101) A61N 2005/0647 (20130101) A61N 2005/0651 (20130101) A61N 2005/0667 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241689 | Furtaw et al. |
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| FUNDED BY |
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| APPLICANT(S) | LI-COR, Inc. (Lincoln, Nebraska) |
| ASSIGNEE(S) | LI-COR, Inc. (Lincoln, Nebraska) |
| INVENTOR(S) | Michael D. Furtaw (Lincoln, Nebraska); Donald T. Lamb (Lincoln, Nebraska) |
| ABSTRACT | Devices and methods are provided for the separation and dispensing of material using a microfluidic electrophoresis column, sheath liquid pump, and exit channel, all on the same monolithic chip. Material is separated in the electrophoresis column and passed into the exit chamber in response to a voltage potential between a first electrode within the electrophoresis column and a terminating electrode integrated into the chip. The terminating electrode can be in the sheath liquid pump chamber, the sheath liquid reservoir, or a separate flow channel that intersects the exit channel along with the electrophoresis column and sheath liquid pump chamber. The flow of sheath liquid into the exit chamber entrains separated analytes into an effluent that is dispensed out of the exit chamber via a discharge outlet. |
| FILED | Monday, August 07, 2017 |
| APPL NO | 15/670896 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) Original (OR) Class B01L 2300/0681 (20130101) B01L 2300/0829 (20130101) B01L 2400/0421 (20130101) B01L 2400/0478 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44721 (20130101) G01N 27/44739 (20130101) G01N 27/44773 (20130101) G01N 27/44782 (20130101) G01N 27/44791 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242296 | Dussault et al. |
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| FUNDED BY |
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| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska) |
| INVENTOR(S) | Patrick H. Dussault (Lincoln, Nebraska); Andrew Olson (Lincoln, Nebraska) |
| ABSTRACT | Disclosed herein is a method of reducing or disproportionating peroxide, comprising combining an organic chalcogenide, an iron salt, and the peroxide in the presence of an additional reductant, which can be the organic chalcogenide. The method can be used to, e.g., prepare alcohols from peroxides and to disproportionate hydrogen peroxide into water and oxygen. |
| FILED | Wednesday, July 17, 2019 |
| APPL NO | 16/514423 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 41/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242314 | Zhou et al. |
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| FUNDED BY |
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| APPLICANT(S) | Dong Zhou (St. Louis, Missouri); Wenhua Chu (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Dong Zhou (St. Louis, Missouri); Wenhua Chu (St. Louis, Missouri) |
| ABSTRACT | The present disclosure relates to the methods for the preparation of reactive [F-18]fluoride in a form of [F-18]sulfonyl fluoride suitable for efficient radiolabeling without an azeotropic evaporation step by the use of anion exchange resin and sulfonyl chloride, and its applications in the manufacturing of PET radiopharmaceuticals. |
| FILED | Wednesday, January 11, 2017 |
| APPL NO | 15/403954 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 59/001 (20130101) C07B 59/002 (20130101) C07B 59/005 (20130101) C07B 2200/05 (20130101) Acyclic or Carbocyclic Compounds C07C 45/63 (20130101) C07C 45/63 (20130101) C07C 47/55 (20130101) C07C 67/307 (20130101) C07C 67/307 (20130101) C07C 69/76 (20130101) C07C 247/04 (20130101) C07C 303/22 (20130101) C07C 303/22 (20130101) C07C 303/22 (20130101) C07C 303/22 (20130101) C07C 309/86 (20130101) C07C 309/87 (20130101) C07C 309/89 (20130101) C07C 315/04 (20130101) Original (OR) Class Heterocyclic Compounds C07D 207/09 (20130101) C07D 213/52 (20130101) C07D 213/71 (20130101) C07D 233/91 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 3/02 (20130101) C07H 19/06 (20130101) Steroids C07J 1/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242317 | Messick et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Wistar Institute of Anatomy and Biology (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Troy E. Messick (Upper Darby, Pennsylvania); Garry R. Smith (Royersford, Pennsylvania); Allen B. Reitz (Lansdale, Pennsylvania); Paul M. Lieberman (Wynnewood, Pennsylvania); Mark E. McDonnell (Lansdale, Pennsylvania); Yan Zhang (Fort Washington, Pennsylvania); Venkata Velvadapu (Ankeny, Iowa) |
| ABSTRACT | Pharmaceutical compositions of the invention comprise EBNA1 inhibitors useful for the treatment of diseases caused by EBNA1 activity such as cancer, infectious mononucleosis, chronic fatigue syndrome, multiple sclerosis, systemic lupus erythematosus and rheumatoid arthritis. Pharmaceutical compositions of the invention also comprise EBNA1 inhibitors useful for the treatment of diseases caused by latent Epstein-Barr Virus (EBV) infection. Pharmaceutical compositions of the invention also comprise EBNA1 inhibitors useful for the treatment of diseases caused by lytic Epstein-Barr Virus (EBV) infection. |
| FILED | Tuesday, July 23, 2019 |
| APPL NO | 16/519590 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/192 (20130101) A61K 31/404 (20130101) A61K 31/496 (20130101) A61K 31/4439 (20130101) Acyclic or Carbocyclic Compounds C07C 53/18 (20130101) C07C 63/66 (20130101) C07C 65/19 (20130101) C07C 65/28 (20130101) C07C 211/27 (20130101) C07C 217/84 (20130101) C07C 229/56 (20130101) C07C 229/64 (20130101) C07C 233/11 (20130101) C07C 233/64 (20130101) C07C 233/65 (20130101) C07C 235/58 (20130101) C07C 255/54 (20130101) C07C 255/55 (20130101) C07C 311/08 (20130101) C07C 311/16 (20130101) C07C 311/17 (20130101) C07C 317/14 (20130101) C07C 317/44 (20130101) C07C 2601/02 (20170501) Heterocyclic Compounds C07D 207/08 (20130101) C07D 207/12 (20130101) C07D 207/14 (20130101) C07D 207/16 (20130101) C07D 207/327 (20130101) Original (OR) Class C07D 209/08 (20130101) C07D 211/70 (20130101) C07D 213/55 (20130101) C07D 213/64 (20130101) C07D 213/74 (20130101) C07D 215/14 (20130101) C07D 231/12 (20130101) C07D 235/06 (20130101) C07D 239/26 (20130101) C07D 249/06 (20130101) C07D 277/30 (20130101) C07D 295/155 (20130101) C07D 307/79 (20130101) C07D 333/54 (20130101) C07D 401/04 (20130101) C07D 401/10 (20130101) C07D 403/10 (20130101) C07D 409/10 (20130101) C07D 417/10 (20130101) C07D 471/04 (20130101) C07D 487/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242326 | Bai et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Yugang Bai (Changsha, China PRC); Steven C. Zimmerman (Champaign, Illinois); Auinash Kalsotra (Champaign, Illinois) |
| ABSTRACT | Abnormally long r(CUG)n repeat expansion is believed to be the major cause of Myotonic dystrophy type 1 (DM1) because it binds to muscleblind-like 1 (MBNL 1) protein which regulates RNA splicing, leading to the mis-splicing of more than 100 pre-mRNAs. The rational design of oligomers with alternating bisamidine and melamine structure resulted in good binding affinity to the RNA target because of a multivalent effect. The oligomers also showed excellent activity in disrupting nuclear foci, reversing the mis-splicing of IR minigene, and sabotaging the toxic RNA biosynthesis. Excellent activity in Drosophila based DM1 models was also observed for the oligomers, rescuing the climbing ability of the flies upon oral treatment. |
| FILED | Thursday, August 23, 2018 |
| APPL NO | 16/641450 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0019 (20130101) A61K 9/2054 (20130101) A61K 9/2059 (20130101) A61K 9/4858 (20130101) Heterocyclic Compounds C07D 251/64 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242338 | Messick et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE WISTAR INSTITUTE (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Wistar Institute (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Troy E. Messick (Upper Darby, Pennsylvania); Paul M. Lieberman (Wynnewood, Pennsylvania); Garry R. Smith (Elverson, Pennsylvania); Arlindo L. Castelhano (New York, New York) |
| ABSTRACT | The invention relates, in certain aspects, to developable forms of certain compounds that are useful to treat and/or prevent EBV infection and related conditions in a subject. The invention further provides EBNA1 inhibitors, and/or pharmaceutical compositions comprising the same, that are useful for the treatment of diseases caused by latent Epstein-Barr Virus (EBV) infection and/or lytic EBV infection. |
| FILED | Thursday, May 16, 2019 |
| APPL NO | 16/414198 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/404 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) A61P 31/22 (20180101) A61P 35/02 (20180101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/13 (20130101) Heterocyclic Compounds C07D 405/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242339 | Mallampalli et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Rama K. Mallampalli (Sewickley, Pennsylvania); Beibei Chen (Sewickley, Pennsylvania); Charleen T. Chu (Wexford, Pennsylvania); Yuan Liu (Sewickley, Pennsylvania) |
| ABSTRACT | A method for treating a neurodegenerative disease or an inflammatory disorder in a subject, comprising administering to the subject in need thereof, a compound, or a pharmaceutically acceptable salt thereof, of formula II: wherein each of R3-R7 is independently H, halogen, optionally-substituted alkyl, amino, alkoxy or hydroxy; R8 is an optionally-substituted heterocycloalkyl; and a is 0 to 3. |
| FILED | Monday, June 25, 2018 |
| APPL NO | 16/624843 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/517 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/16 (20180101) A61P 25/28 (20180101) Heterocyclic Compounds C07D 405/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242368 | Harris |
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| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Samantha P. Harris (Tucson, Arizona) |
| ABSTRACT | Methods and compositions for rapidly replacing cMyBP-C in sarcomeres featuring the creation of Spy-C mice, which are mice genetically engineered to express cMyBP-C with a protease recognition site and SpyTag peptide introduced into the cMyBP-C gene. In permeabilized myocytes from the Spy-C mice, the cMyBP-C protein can be cleaved at the protease recognition site, and the N-Terminus of cMyBP-C can be removed while the C-terminus remains anchored to the thick filament. A new peptide featuring the SpyCatcher sequence can be covalently bonded to the remaining portion of cMyBP-C, thereby creating a modified cMyBP-C protein. The methods and compositions of the present invention allow for the reconstitution of full-length cMyBP-C at the precise position of native cMyBP-C in the sarcomere and allow for a variety of modifications to be introduced to cMyBP-C in situ. |
| FILED | Monday, September 23, 2019 |
| APPL NO | 16/579445 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/47 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/907 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242378 | Bornholdt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MAPP BIOPHARMACEUTICAL, INC. (San Diego, California); Albert Einstein College of Medicine (Bronx, New York); Adimab, LLC (Lebanon, New Hampshire) |
| ASSIGNEE(S) | MAPP BIOPHARMACEUTICAL, INC. (San Diego, California); ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York); ADIMAB, LLC (Lebanon, New Hampshire) |
| INVENTOR(S) | Zachary A. Bornholdt (Encinitas, California); Larry Zeitlin (San Diego, California); Kartik Chandran (Brooklyn, New York); Anna Wec (Lebanon, New Hampshire); Laura Walker (Norwich, Vermont) |
| ABSTRACT | Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially, similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus. |
| FILED | Tuesday, June 09, 2020 |
| APPL NO | 16/896980 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 2039/55 (20130101) A61K 2039/57 (20130101) A61K 2039/62 (20130101) A61K 2039/505 (20130101) A61K 2039/545 (20130101) A61K 2039/6075 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242379 | Bornholdt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MAPP BIOPHARMACEUTICAL, INC. (San Diego, California); Albert Einstein College of Medicine (Bronx, New York); Adimab, LLC (Lebanon, New Hampshire) |
| ASSIGNEE(S) | MAPP BIOPHARMACEUTICAL, INC. (San Diego, California); ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York); ADIMAB, LLC (Lebanon, New Hampshire) |
| INVENTOR(S) | Zachary A. Bornholdt (Encinitas, California); Larry Zeitlin (San Deigo, California); Kartik Chandran (Brooklyn, New York); Anna Wec (Lebanon, New Hampshire); Laura Walker (Norwich, Vermont) |
| ABSTRACT | Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus. |
| FILED | Tuesday, June 09, 2020 |
| APPL NO | 16/896991 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 2039/55 (20130101) A61K 2039/57 (20130101) A61K 2039/62 (20130101) A61K 2039/505 (20130101) A61K 2039/545 (20130101) A61K 2039/6075 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242509 | Deng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York) |
| INVENTOR(S) | Liang Deng (New York, New York); Stewart Shuman (New York, New York); Ning Yang (New York, New York); Taha Merghoub (New York, New York); Jedd Wolchok (New York, New York) |
| ABSTRACT | Disclosed herein are methods and compositions related to the treatment, prevention, and/or amelioration of cancer in a subject in need thereof. In particular aspects, the present technology relates to the use of poxviruses, including a recombinant modified vaccinia Ankara (MVA) virus or vaccinia virus with deletion of vaccinia host-range factor C7 (MVAΔC7L and VACVΔC7L, respectively), alone or in combination with immune checkpoint blocking agents, as an oncolytic and immunotherapeutic composition. In some embodiments, the technology of the present disclosure relates to a MVAΔC7L or VACVΔC7L virus further modified to express human Fms-like tyrosine kinase 3 ligand (Flt3L). |
| FILED | Friday, May 11, 2018 |
| APPL NO | 16/612127 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/285 (20130101) A61K 2039/54 (20130101) A61K 2039/525 (20130101) A61K 2039/55588 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 2710/24121 (20130101) C12N 2710/24131 (20130101) C12N 2710/24143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242532 | Guo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio); Ball State University (Muncie, Indiana) |
| ASSIGNEE(S) | Ohio State Innovation Foundation (Columbus, Ohio); Ball State University (Muncie, Indiana) |
| INVENTOR(S) | Peixuan Guo (Dublin, Ohio); Daniel Jasinski (Columbus, Ohio); Hui Li (San Francisco, California); Emil Khisamutdinov (Muncie, Indiana) |
| ABSTRACT | Disclosed herein are three-dimensional cage molecules, wherein the cage molecule is composed of RNA. Also disclosed is a composition including the three-dimensional cage molecule, as well as a pharmaceutical composition containing the three-dimensional cage molecule. Also disclosed herein are methods of administering a cage molecule, composition, or formulation thereof to a subject in need thereof. |
| FILED | Wednesday, May 10, 2017 |
| APPL NO | 16/091747 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/04 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/10 (20130101) C12N 15/11 (20130101) C12N 15/113 (20130101) C12N 15/115 (20130101) Original (OR) Class C12N 15/117 (20130101) C12N 2310/16 (20130101) C12N 2310/17 (20130101) C12N 2310/341 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242561 | Ju et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jingyue Ju (Englewood Cliffs, New Jersey); Dae Hyun Kim (Northbrook, Illinois); Jia Guo (Chandler, Arizona); Qinglin Meng (Foster City, California); Zengmin Li (Flushing, New York); Huanyan Cao (Zhangzhou, China PRC) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Jingyue Ju (Englewood Cliffs, New Jersey); Dae Hyun Kim (Northbrook, Illinois); Jia Guo (Chandler, Arizona); Qinglin Meng (Foster City, California); Zengmin Li (Flushing, New York); Huanyan Cao (Zhangzhou, China PRC) |
| ABSTRACT | This invention provides a process for sequencing nucleic acids using 3′ modified deoxynucleotide analogues or 3′ modified deoxyinosine triphosphate analogues, and 3′ modified dideoxynucleotide analogues having a detectable marker attached thereto. |
| FILED | Monday, April 15, 2019 |
| APPL NO | 16/384461 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/70 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/04 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 1/6876 (20130101) C12Q 2523/107 (20130101) C12Q 2523/319 (20130101) C12Q 2535/101 (20130101) C12Q 2535/113 (20130101) C12Q 2563/107 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242562 | Salk et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| INVENTOR(S) | Jesse Salk (Seattle, Washington); Lawrence A. Loeb (Bellevue, Washington); Michael Schmitt (Seattle, Washington) |
| ABSTRACT | Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand. This method uniquely capitalizes on the redundant information stored in double-stranded DNA, thus overcoming technical limitations of prior methods utilizing data from only one of the two strands. |
| FILED | Thursday, August 30, 2018 |
| APPL NO | 16/118305 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6876 (20130101) Original (OR) Class C12Q 2525/179 (20130101) C12Q 2525/185 (20130101) C12Q 2525/191 (20130101) C12Q 2525/191 (20130101) C12Q 2535/119 (20130101) C12Q 2535/119 (20130101) C12Q 2535/122 (20130101) C12Q 2563/179 (20130101) C12Q 2565/514 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242572 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| ASSIGNEE(S) | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (Bethesda, Maryland) |
| INVENTOR(S) | Linfa Wang (Wandana Heights, Australia); Glenn A. Marsh (Leopold, Australia); Hume Field (Ormiston, Australia); Christopher Broder (Silver Spring, Maryland) |
| ABSTRACT | The present disclosure is directed towards a virus, called Cedar Virus, and its methods of use. |
| FILED | Tuesday, March 12, 2019 |
| APPL NO | 16/351380 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/12 (20130101) A61K 2039/543 (20130101) Peptides C07K 14/005 (20130101) C07K 16/1027 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2760/18221 (20130101) C12N 2760/18222 (20130101) C12N 2760/18231 (20130101) C12N 2760/18234 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/70 (20130101) C12Q 1/701 (20130101) Original (OR) Class C12Q 2600/136 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11243188 | Pourmand et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Nader Pourmand (San Mateo, California); Boaz Vilozny (Santa Cruz, California); Paolo Actis (London, United Kingdom); R. Adam Seger (Santa Cruz, California) |
| ABSTRACT | Disclosed are methods and devices for detection of ion migration and binding, utilizing a nanopipette adapted for use in an electrochemical sensing circuit. The nanopipette may be functionalized on its interior bore with metal chelators for binding and sensing metal ions or other specific binding molecules such as boronic acid for binding and sensing glucose. Such a functionalized nanopipette is comprised in an electrical sensor that detects when the nanopipette selectively and reversibly binds ions or small molecules. Also disclosed is a nanoreactor, comprising a nanopipette, for controlling precipitation in aqueous solutions by voltage-directed ion migration, wherein ions may be directed out of the interior bore by a repulsing charge in the bore. |
| FILED | Friday, May 24, 2019 |
| APPL NO | 16/422735 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/021 (20130101) B01L 3/50273 (20130101) B01L 2300/0896 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 35/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3277 (20130101) G01N 27/44791 (20130101) Original (OR) Class G01N 33/48721 (20130101) Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 60/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11243208 | Katchman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona); THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona); THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Benjamin Katchman (Tempe, Arizona); Karen Anderson (Scottsdale, Arizona); Garrick Wallstrom (Mesa, Arizona); Joshua LaBaer (Chandler, Arizona); Daniel Cramer (Chestnut Hill, Massachusetts) |
| ABSTRACT | Compositions and methods relating to a panel of antigen biomarkers for the early detection of ovarian cancer. The compositions and methods encompass antigen biomarkers coupled to a substrate, with the biomarkers being selected from the group consisting of one or more of ICAM3, CTAG2, p53, STYXL1, PVR, POMC, NUDT11, TRIM39, UHMK1, KSR1, and NXF3. |
| FILED | Tuesday, July 11, 2017 |
| APPL NO | 16/317184 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57449 (20130101) Original (OR) Class G01N 2800/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11243213 | Tarca et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WAYNE STATE UNIVERSITY (Detroit, Michigan); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICE (Bethesda, Maryland) |
| ASSIGNEE(S) | Wayne State University (Detroit, Michigan); The United States of America as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Adi L. Tarca (South Lyon, Michigan); Piya Chaemsaithong (Shatin, China Hong Kong); Tinnakorn Chaiworapongsa (Grosse Pointe Park, Michigan); Sonia S. Hassan (Novi, Michigan); Roberto Romero (Grosse Pointe, Michigan) |
| ABSTRACT | Biomarkers tests which can be used to predict a positive or negative risk of preeclampsia are described. More specifically, a panel of biomarkers including MMP-7 and gpIIbIIIa, described. The test is useful to predict preeclampsia when a biological sample is obtained between the 16th and 22nd week of pregnancy. Prediction later in pregnancy can be achieved by a combination of Siglec-6, Activin A, ALCAM, and/or FCN2. |
| FILED | Monday, November 07, 2016 |
| APPL NO | 15/773978 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/16 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/158 (20130101) Enzymes C12Y 304/24007 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/689 (20130101) Original (OR) Class G01N 2333/96494 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11243215 | John et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Varghese John (Los Angeles, California); Jesus Campagna (Playa Del Rey, California); Tina Bilousova (Santa Monica, California); Patricia R. Spilman (Mill Valley, California); Peter James Heinzelman (Los Angeles, California); Asa Hatami (Los Angeles, California); Mohammad Parvez Alam (Los Angeles, California) |
| ABSTRACT | In various embodiments methods are provided for identifying and/or quantifying one or more antigens of interest (biomarkers) on the surface of cell- or tissue-specific exosomes. In an illustrative embodiments the methods comprise: i) incubating a population of exosomes with one or more tissue-specific antibodies that bind an antigen specific to a tissue or cell type of interest that produces exosomes, where the tissue specific antibodies are attached to acceptor bead or magnetic beads so the antibodies bind exosomes displaying the antigen; ii) obtaining a purified population of exosomes bound by the tissue specific antibodies with and/or without photocleavable linker based technology; iii) incubating a test subset of the isolated tissue-specific exosomes with acceptor beads attached to test antibodies that bind an antigen of interest thereby binding exosomes that display the antigen of interest and a control subset with negative control acceptor beads; v) incubating the test subset of isolated exosomes and the control subset of exosomes with a donor-bearing antibody that binds an exosome specific antigen; and vi) detecting a signal produced upon illumination of the control subset and/or the test; and vii) detecting the antigen(s) of interest. |
| FILED | Friday, January 13, 2017 |
| APPL NO | 16/070249 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Heterocyclic Compounds C07D 207/46 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/542 (20130101) G01N 33/567 (20130101) G01N 33/6896 (20130101) Original (OR) Class G01N 33/54313 (20130101) G01N 33/54326 (20130101) G01N 33/54353 (20130101) G01N 33/57484 (20130101) G01N 2570/00 (20130101) G01N 2800/52 (20130101) G01N 2800/285 (20130101) G01N 2800/2821 (20130101) G01N 2800/2835 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11243284 | Overall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HeartVista, Inc. (Los Altos, California) |
| ASSIGNEE(S) | HEARTVISTA, INC. (Los Altos, California) |
| INVENTOR(S) | William Overall (Los Altos, California); Juan Santos (Los Altos, California) |
| ABSTRACT | A computer-implemented method for sequencing magnetic resonance imaging waveforms uses a multistage sequencing hardware. A method comprises creating, with the aid of a computer processor, an active memory region that includes waveforms and schedules being played, and creating one or more buffer memory regions that contain waveforms and schedules not currently being played. Next, the waveforms and schedules in the one or more buffer memory regions may be updated while waveforms may be played in the active memory region. Upon completion of the waveform playback in the active memory region, the active and buffer memory regions may be swapped so that the former buffer memory region becomes the active memory region, and the former active memory region becomes the buffer memory region. The method may be repeated as needed until the imaging process is completed or otherwise halted. |
| FILED | Wednesday, January 08, 2020 |
| APPL NO | 16/737227 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/543 (20130101) G01R 33/561 (20130101) G01R 33/3852 (20130101) G01R 33/4822 (20130101) G01R 33/4824 (20130101) G01R 33/5608 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11243391 | Hillman |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Elizabeth M. C. Hillman (New York, New York) |
| ABSTRACT | Implementing swept, confocally aligned planar excitation (SCAPE) imaging with asymmetric magnification in the detection arm provides a number of significant advantages. In some preferred embodiments, the asymmetric magnification is achieved using cylindrical lenses in the detection arm that are oriented to increase the magnification of the intermediate image in the width direction but not in the depth direction. SCAPE imaging may also be improved by using an SLM to modify a characteristic of the sheet of excitation light that is projected into the sample. Additional embodiments include a customized version of SCAPE that is optimized for imaging the retina at the back of an eyeball in living subjects. |
| FILED | Tuesday, May 30, 2017 |
| APPL NO | 16/303017 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/14 (20130101) A61B 3/1025 (20130101) Optical Elements, Systems, or Apparatus G02B 21/006 (20130101) G02B 21/0032 (20130101) G02B 21/0048 (20130101) G02B 21/0052 (20130101) G02B 21/0072 (20130101) G02B 21/0076 (20130101) G02B 21/367 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 5/23296 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11244104 | Jain et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vignet Incorporated (Fairfax, Virginia) |
| ASSIGNEE(S) | VigNet Incorporated (Fairfax, Virginia) |
| INVENTOR(S) | Neeta Jain (Fairfax, Virginia); Yue Cao (Vienna, Virginia); Dave Klein (Oakton, Virginia); Praduman Jain (Fairfax, Virginia) |
| ABSTRACT | In some implementations, a system dynamically adjusts an electronic form of an application based on user data and form data specified for the electronic form. Form data that specifies characteristics of the electronic form is initially received by a computing device. The form data specifies one or more rules configured to vary the content of the electronic form that is presented for different users. User data indicating characteristics of a user is then obtained by the computing device. An interactive element is then selected from among a set of multiple interactive elements based on the received user data and the rules in the received form data. A view of the electronic form is customized for the user by including, in the customized view, the interactive element. The view of the customized electronic form is then displayed by the computing device. |
| FILED | Wednesday, March 04, 2020 |
| APPL NO | 16/808448 |
| ART UNIT | 2144 — Graphical User Interface and Document Processing |
| CURRENT CPC | Electric Digital Data Processing G06F 40/103 (20200101) G06F 40/174 (20200101) Original (OR) Class G06F 40/186 (20200101) G06F 40/197 (20200101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/20 (20180101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11244452 | Castro-Gonzalez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Universidad Politecnica De Madrid (Madrid, Spain) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Carlos Castro-Gonzalez (Cambridge, Massachusetts); Ian Butterworth (Cambridge, Massachusetts); Aurelien Bourquard (Cambridge, Massachusetts); Alvaro Sanchez-Ferro (Madrid, Spain); Jason Tucker-Schwartz (Melrose, Massachusetts); Alberto Pablo-Trinidad (Madrid, Spain); Maria J. Ledesma-Carbayo (Madrid, Spain); Tom Vettenburg (Dundee, United Kingdom) |
| ABSTRACT | A system for non-invasive hematological measurements includes a platform to receive a body portion of a user and an imaging device to acquire a set of images of a capillary bed in the body portion. For each image, a controller detects one or more capillaries in the body portion of the finger to identify a first set of capillaries by estimating one or more attributes of each capillary (e.g., structural attributes, flow attributes, imaging attributes, or combinations thereof), wherein at least one attribute of each capillary meets a predetermined criterion. The controller also identifies a second set of capillaries from the first set of capillaries such that each capillary of the second set of capillaries is visible in a predetermined number of images of the set of images. |
| FILED | Tuesday, October 16, 2018 |
| APPL NO | 16/162006 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0261 (20130101) A61B 5/489 (20130101) A61B 5/1455 (20130101) A61B 5/6826 (20130101) A61B 5/7203 (20130101) A61B 5/7267 (20130101) A61B 5/14546 (20130101) A61B 2576/02 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/66 (20130101) G06K 9/00885 (20130101) G06K 2009/00932 (20130101) G06K 2009/00939 (20130101) Image Data Processing or Generation, in General G06T 7/0014 (20130101) Original (OR) Class G06T 2207/10016 (20130101) G06T 2207/10152 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30101 (20130101) Technologies for Adaptation to Climate Change Y02A 90/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11241188 | Widge et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts); Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts); Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Alik Widge (Somerville, Massachusetts); Emad Eskandar (Swampscott, Massachusetts); Darin Dougherty (Wellesley, Massachusetts); Uri Tzvi Eden (Medford, Massachusetts); Xinyi Deng (Boston, Massachusetts); Ali Yousefi (Brookline, Massachusetts); Angelique Paulk (Brighton, Massachusetts) |
| ABSTRACT | A system and methods for monitoring and controlling a mental state of a subject are provided. In some aspects, a method includes receiving physiological and behavioral data acquired using the plurality of sensors while the subject is performing a task, and applying, using the data, a state-space framework to determine a plurality of decoder parameters correlating brain activity and behavior with a mental state of the subject. The method also includes identifying the mental state of the subject using the decoder parameters, and generating a report indicating the mental state of the subject. In some aspects, the method further includes generating, based on the identified mental state, a brain stimulation to treat a brain condition of the subject. |
| FILED | Thursday, June 30, 2016 |
| APPL NO | 15/740975 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/162 (20130101) A61B 5/316 (20210101) A61B 5/377 (20210101) A61B 5/4064 (20130101) A61B 5/4088 (20130101) Original (OR) Class A61B 2560/0238 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36139 (20130101) Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 15/00 (20180101) G16H 20/70 (20180101) G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241190 | Viswanath et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Satish Viswanath (Beachwood, Ohio); Iulia Barbur (Akron, Ohio) |
| ABSTRACT | Embodiments discussed herein facilitate predicting response to therapy in Crohn's disease. A first set of embodiments discussed herein relates to accessing a radiological image of a region of tissue demonstrating Crohn's disease associated with a patient; defining a mesenteric fat region by segmenting mesenteric fat represented in the radiological image; extracting a set of radiomic features from the mesenteric fat region; providing the set of radiomic features to a machine learning classifier configured to compute a probability of response to therapy in Crohn's disease based, at least in part, on the set of radiomic features; receiving, from the machine learning classifier, a probability that the region of tissue will respond to therapy; generating a classification of the patient as a responder or non-responder based, at least in part, on the probability; and displaying the classification. |
| FILED | Monday, September 16, 2019 |
| APPL NO | 16/571454 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0037 (20130101) A61B 5/4255 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6231 (20130101) Computer Systems Based on Specific Computational Models G06N 7/046 (20130101) G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) G06T 2207/10088 (20130101) G06T 2207/30028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241194 | Reifman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Army (Ft. Detrick, Maryland) |
| ASSIGNEE(S) | The Government of the United States, as represented by the Secretary of the Army (Fort Detrick, Maryland) |
| INVENTOR(S) | Jaques Reifman (New Market, Maryland); Jianbo Liu (Lexington, Virginia); Nancy Wesensten (Silver Spring, Maryland); Thomas Balkin (Ellicott City, Maryland); Sridhar Ramakrishnan (Frederick, Maryland); Maxim Y. Khitrov (Rockville, Maryland) |
| ABSTRACT | A system, method and apparatus is disclosed, comprising a biomathetical model for optimizing cognitive performance in the face of sleep deprivation that integrates novel and nonobvious biomathematical models for quantifying performance impairment for both chronic sleep restriction and total sleep deprivation; the dose-dependent effects of caffeine on human vigilance; and the pheonotypical response of a particular user to caffeine dosing, chronic sleep restriction and total sleep deprivation in user-friendly software application which itself may be part of a networked system. |
| FILED | Wednesday, June 08, 2016 |
| APPL NO | 15/580907 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/00 (20130101) A61B 5/02 (20130101) A61B 5/11 (20130101) A61B 5/18 (20130101) A61B 5/103 (20130101) A61B 5/113 (20130101) A61B 5/162 (20130101) A61B 5/165 (20130101) A61B 5/0255 (20130101) A61B 5/486 (20130101) Original (OR) Class A61B 5/1118 (20130101) A61B 5/4806 (20130101) A61B 5/4839 (20130101) A61B 5/4857 (20130101) A61B 5/6898 (20130101) A61B 5/7225 (20130101) A61B 5/7275 (20130101) A61B 5/7435 (20130101) A61B 5/7475 (20130101) A61B 2503/20 (20130101) A61B 2560/0475 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 15/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241380 | Freeman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | William Freeman (Del Mar, California); Michael J. Sailor (La Jolla, California); Lingyun Cheng (San Diego, California); Frederique Cunin (Montpellier, France); Emily Anglin (San Diego, California); Yang Yang Li (Hong Kong, China Hong Kong) |
| ABSTRACT | A minimally invasive controlled drug delivery system for delivering a particular drug or drugs to a particular location of the eye, the system including a porous film template having pores configured and dimensioned to at least partially receive at least one drug therein, and wherein the template is dimensioned to be delivered into or onto the eye. |
| FILED | Monday, November 06, 2017 |
| APPL NO | 15/804856 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/0017 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) Original (OR) Class A61K 9/0051 (20130101) A61K 9/1611 (20130101) A61K 9/7007 (20130101) A61K 31/573 (20130101) A61K 47/24 (20130101) A61K 47/26 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241394 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Liangfang Zhang (San Diego, California); Che-Ming Jack Hu (Novato, California); Ronnie H. Fang (San Diego, California); Brian T. Luk (San Diego, California); Kuei-Chun Wang (San Diego, California); Shu Chien (La Jolla, California) |
| ABSTRACT | The present invention relates to prevention and/or treatment of diseases or disorders associated with a damaged or leaky vasculature in a subject. The present invention provides for methods, combinations and pharmaceutical compositions for preventing and/or treating a disease or disorder associated with a damaged or leaky vasculature in a subject, using, inter alia, an effective amount of a nanoparticle comprising an inner core comprising a non-cellular material, an outer surface comprising a cellular membrane derived from a platelet; and optionally an agent for preventing, treating, diagnosing, or prognosing the disease or disorder and/or monitoring prevention or treatment of the disease or disorder. Exemplary diseases or disorders include hemorrhage (bleeding), cardiovascular diseases or disorders, diseases or disorders associated with narrowing of a blood vessel, tumors or cancers. |
| FILED | Tuesday, June 07, 2016 |
| APPL NO | 15/737566 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5153 (20130101) A61K 9/5169 (20130101) A61K 9/5176 (20130101) Original (OR) Class A61K 31/337 (20130101) A61K 47/6901 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/04 (20180101) A61P 9/00 (20180101) A61P 35/00 (20180101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 30/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241511 | Mahmood et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Umar Mahmood (Winchester, Massachusetts); Benjamin Larimer (Woburn, Massachusetts) |
| ABSTRACT | Provided herein are compositions useful for imaging HER3. An exemplary composition provided herein is useful as a radiotracer for position emission tomography (PET) imaging. Methods of imaging HER3 and combination therapies comprising the HER3 imaging agents are also provided. |
| FILED | Friday, December 29, 2017 |
| APPL NO | 16/475020 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/088 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242244 | Plochowietz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Anne Plochowietz (Palo Alto, California); Bradley Rupp (San Francisco, California); Jengping Lu (Fremont, California); Julie A. Bert (East Palo Alto, California); Lara S. Crawford (Los Altos, California); Sourobh Raychaudhuri (Mountain View, California); Eugene M. Chow (Palo Alto, California); Matthew Shreve (Mountain View, California); Sergey Butylkov (Oakland, California) |
| ABSTRACT | Disclosed are methods and systems of controlling the placement of micro-objects on the surface of a micro-assembler. Control patterns may be used to cause electrodes of the micro-assembler to generate dielectrophoretic (DEP) and electrophoretic (EP) forces which may be used to manipulate, move, position, or orient one or more micro-objects on the surface of the micro-assembler. The control patterns may be part of a library of control patterns. |
| FILED | Monday, December 31, 2018 |
| APPL NO | 16/237419 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 99/002 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/67271 (20130101) H01L 21/67294 (20130101) H01L 24/95 (20130101) H01L 2224/95133 (20130101) H01L 2224/95145 (20130101) H01L 2924/1461 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49131 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242262 | Ravichandran et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Texas Biochemicals Inc. (College Station, Texas) |
| ASSIGNEE(S) | TEXAS BIOCHEMICALS INC. (, None) |
| INVENTOR(S) | Duraiswamy Ravichandran (College Station, Texas); V S Reddy Channu (College Station, Texas) |
| ABSTRACT | A method is provided for producing an article which is transparent to IR wavelength in the region of 4 μm to 9 μm. The method includes the steps of (a) Producing ultra-fine powders of ZnS, (b) followed by pretreatment of the ultra-fine powders under reduced gas conditions including H2, H2S, N2, Ar and mixtures there of (c) followed by vacuum (3×10−6 torr) treatment to remove oxygen and sulfates adsorbed to the surface disposing a plurality of nano-particles on a substrate, wherein said nanoparticles comprise ZnS with ultra-high purity of cubic phase; (b) subjecting the nano-particles to spark plasma sintering thereby producing a sintered ZnS product with IR transmission reaching 75% in the wavelength range of 4 μm to 9 μm. |
| FILED | Tuesday, December 27, 2016 |
| APPL NO | 15/390853 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 3/003 (20130101) B28B 11/243 (20130101) Non-metallic Elements; Compounds Thereof; C01B 19/007 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 9/08 (20130101) C01G 11/02 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/82 (20130101) C01P 2004/03 (20130101) C01P 2004/61 (20130101) C01P 2004/64 (20130101) C01P 2006/60 (20130101) C01P 2006/90 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242367 | Lawrence et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Silk Technologies, Ltd. (Plymouth, Minnesota) |
| ASSIGNEE(S) | Silk Technologies, Ltd. (Plymouth, Minnesota) |
| INVENTOR(S) | Brian D. Lawrence (Tampa, Florida); David W. Infanger (Maple Grove, Minnesota) |
| ABSTRACT | Described herein are methods for reducing inflammation by administration of an effective amount of silk-derived proteins (SDP) or a fraction thereof to a subject having an inflammatory condition. The methods include the treatment of inflammatory conditions and wounds, including corneal wounds, comprising the topical administration of an effective amount of SDP material as described herein. |
| FILED | Saturday, August 12, 2017 |
| APPL NO | 16/324844 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/14 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 38/00 (20130101) A61K 38/012 (20130101) A61K 47/02 (20130101) A61K 47/10 (20130101) A61K 47/26 (20130101) A61K 47/34 (20130101) A61K 47/38 (20130101) A61K 47/42 (20130101) A61K 47/183 (20130101) Peptides C07K 14/43586 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242375 | Adusumilli et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| INVENTOR(S) | Prasad S. Adusumilli (New York, New York); Michel Sadelain (New York, New York) |
| ABSTRACT | Disclosed herein are cells that are immune cells or precursor cells thereof, which cells recombinantly express a chimeric antigen receptor (CAR), and a dominant negative form of an inhibitor of a cell-mediated immune response of the immune cell, wherein the CAR binds to a cancer antigen. Also disclosed herein are T cells that recognize and are sensitized to a cancer antigen, which T cells recombinantly express a dominant negative form of an inhibitor of a T cell-mediated immune response. Additionally provided are methods of using such cells to treat cancer in a subject in need thereof. |
| FILED | Friday, September 02, 2016 |
| APPL NO | 15/757276 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 35/28 (20130101) A61K 38/00 (20130101) A61K 38/177 (20130101) A61K 38/193 (20130101) A61K 38/193 (20130101) A61K 38/1774 (20130101) A61K 38/2013 (20130101) A61K 38/2013 (20130101) A61K 38/4873 (20130101) A61K 39/0011 (20130101) A61K 39/00117 (20180801) A61K 39/00118 (20180801) A61K 39/001104 (20180801) A61K 39/001106 (20180801) A61K 39/001109 (20180801) A61K 39/001112 (20180801) A61K 39/001113 (20180801) A61K 39/001114 (20180801) A61K 39/001119 (20180801) A61K 39/001122 (20180801) A61K 39/001124 (20180801) A61K 39/001126 (20180801) A61K 39/001128 (20180801) A61K 39/001129 (20180801) A61K 39/001153 (20180801) A61K 39/001157 (20180801) A61K 39/001166 (20180801) A61K 39/001168 (20180801) A61K 39/001171 (20180801) A61K 39/001174 (20180801) A61K 39/001182 (20180801) A61K 39/001186 (20180801) A61K 39/001188 (20180801) A61K 39/001192 (20180801) A61K 39/001193 (20180801) A61K 39/001195 (20180801) A61K 39/39558 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7051 (20130101) Original (OR) Class C07K 14/70503 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 14/70578 (20130101) C07K 16/30 (20130101) C07K 16/3069 (20130101) C07K 2317/622 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) C07K 2319/33 (20130101) C07K 2319/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 5/0638 (20130101) C12N 9/6472 (20130101) C12N 2510/00 (20130101) Enzymes C12Y 304/22062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242378 | Bornholdt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MAPP BIOPHARMACEUTICAL, INC. (San Diego, California); Albert Einstein College of Medicine (Bronx, New York); Adimab, LLC (Lebanon, New Hampshire) |
| ASSIGNEE(S) | MAPP BIOPHARMACEUTICAL, INC. (San Diego, California); ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York); ADIMAB, LLC (Lebanon, New Hampshire) |
| INVENTOR(S) | Zachary A. Bornholdt (Encinitas, California); Larry Zeitlin (San Diego, California); Kartik Chandran (Brooklyn, New York); Anna Wec (Lebanon, New Hampshire); Laura Walker (Norwich, Vermont) |
| ABSTRACT | Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially, similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus. |
| FILED | Tuesday, June 09, 2020 |
| APPL NO | 16/896980 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 2039/55 (20130101) A61K 2039/57 (20130101) A61K 2039/62 (20130101) A61K 2039/505 (20130101) A61K 2039/545 (20130101) A61K 2039/6075 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242379 | Bornholdt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MAPP BIOPHARMACEUTICAL, INC. (San Diego, California); Albert Einstein College of Medicine (Bronx, New York); Adimab, LLC (Lebanon, New Hampshire) |
| ASSIGNEE(S) | MAPP BIOPHARMACEUTICAL, INC. (San Diego, California); ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York); ADIMAB, LLC (Lebanon, New Hampshire) |
| INVENTOR(S) | Zachary A. Bornholdt (Encinitas, California); Larry Zeitlin (San Deigo, California); Kartik Chandran (Brooklyn, New York); Anna Wec (Lebanon, New Hampshire); Laura Walker (Norwich, Vermont) |
| ABSTRACT | Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus. |
| FILED | Tuesday, June 09, 2020 |
| APPL NO | 16/896991 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 2039/55 (20130101) A61K 2039/57 (20130101) A61K 2039/62 (20130101) A61K 2039/505 (20130101) A61K 2039/545 (20130101) A61K 2039/6075 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242553 | Lieberman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Judy Lieberman (Brookline, Massachusetts); Shen Mynn Tan (Newton, Massachusetts) |
| ABSTRACT | The present invention provides systems and methods for identifying, isolating, and/or characterizing microRNAs, their targets, and microRNA response elements, and for predicting their biological function. |
| FILED | Friday, January 17, 2014 |
| APPL NO | 14/761791 |
| ART UNIT | 1699 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1006 (20130101) C12N 2310/141 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) Original (OR) Class C12Q 1/6816 (20130101) C12Q 1/6886 (20130101) C12Q 2521/327 (20130101) C12Q 2525/207 (20130101) C12Q 2527/125 (20130101) C12Q 2600/178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242572 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| ASSIGNEE(S) | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (Bethesda, Maryland) |
| INVENTOR(S) | Linfa Wang (Wandana Heights, Australia); Glenn A. Marsh (Leopold, Australia); Hume Field (Ormiston, Australia); Christopher Broder (Silver Spring, Maryland) |
| ABSTRACT | The present disclosure is directed towards a virus, called Cedar Virus, and its methods of use. |
| FILED | Tuesday, March 12, 2019 |
| APPL NO | 16/351380 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/12 (20130101) A61K 2039/543 (20130101) Peptides C07K 14/005 (20130101) C07K 16/1027 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2760/18221 (20130101) C12N 2760/18222 (20130101) C12N 2760/18231 (20130101) C12N 2760/18234 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/70 (20130101) C12Q 1/701 (20130101) Original (OR) Class C12Q 2600/136 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242576 | Wengrenovich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Nicholas J. Wengrenovich (Evanston, Illinois); Gregory B. Olson (Riverswood, Illinois) |
| ABSTRACT | An optimized Gamma-prime (γ′) strengthened austenitic transformation induced plasticity (TRIP) steel comprises a composition designed and processed such that the optimized γ′ strengthened austenitic TRIP steel meets property objectives comprising a yield strength of 896 MPa (130 ksi), and an austenite stability designed to have Msσ(sh)=−40° C., wherein Msσ(sh) is a temperature for shear, and wherein the property objectives are design specifications of the optimized γ′ strengthened austenitic TRIP steel. The optimized γ′ strengthened austenitic TRIP steel is Blastalloy TRIP 130. |
| FILED | Monday, April 10, 2017 |
| APPL NO | 15/483559 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 6/02 (20130101) Original (OR) Class C21D 6/004 (20130101) C21D 7/13 (20130101) C21D 2211/001 (20130101) C21D 2211/004 (20130101) Alloys C22C 38/06 (20130101) C22C 38/44 (20130101) C22C 38/46 (20130101) C22C 38/50 (20130101) C22C 38/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11243056 | Rastegar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Omnitek Partners LLC (Ronkonkoma, New York) |
| ASSIGNEE(S) | OMNITEK PARTNERS LLC (Ronkonkoma, New York) |
| INVENTOR(S) | Jahangir S Rastegar (Stony Brook, New York); Jacques Fischer (Sound Beach, New York) |
| ABSTRACT | A munition including: a control surface actuation device including: an actuator having two or more pistons, each of the pistons being movable between an extended and retracted position, the retracted position resulting from an activation of each of the two or more pistons; and a movable rack having a pocket corresponding to each of the two or more pistons, each pocket being engageable with a corresponding portion of each of the two or more pistons, a distance between the pockets being different than a distance between the portions of the two or more pistons, such that activation of the portion into the corresponding pocket sequentially translates the rack; and a control surface operatively connected to the rack such that translation of the rack rotates the control surface. |
| FILED | Tuesday, August 25, 2020 |
| APPL NO | 17/002623 |
| ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 10/18 (20130101) F42B 10/64 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11243200 | Shih et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Wan Y. Shih (Bryn Mawr, Pennsylvania); Wei Wu (Philadelphia, Pennsylvania); Wei-Heng Shih (Bryn Mawr, Pennsylvania); Mehmet Cagri Soylu (Melikgazi, Turkey); Haitao Guo (Carmel, Indiana); Suresh G. Joshi (Secane, Pennsylvania); Ceyhun Ekrim Kirimli (Thunder Bay, Canada); Ying-Hsiu Su (Audubon, Pennsylvania) |
| ABSTRACT | A piezoelectric plate sensor comprising a piezoelectric layer; two electrodes; and an insulation layer. The insulation layer is produced by soaking the piezoelectric layer and two electrodes in a mercaptopropyltrimethoxysilane solution with an amount of water from 0.1 v/v. % to about 1 v/v % and at pH from about 8 to about 150 for a period from about 8 to about 15 hours, and the mercaptopropyltrimethoxysilane solution has a concentration of mercaptopropyltrimethoxysilane from about 0.01 v/v % to about 0.5 v/v %. A method of detecting a biomolecule in a sample using the piezoelectric plate sensor in particular, that of detecting a genetic marker with PCR sensitivity and specificity without the need of DNA isolation or amplification is also provided. The piezoelectric plate sensor may be used to diagnose various diseases including breast cancer, myocardial infarction, diarrhea, Clostridium difficile infection, and hepatitis B infection. |
| FILED | Tuesday, December 11, 2018 |
| APPL NO | 16/216848 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) C12Q 1/6825 (20130101) C12Q 2565/607 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/022 (20130101) G01N 29/036 (20130101) G01N 33/54373 (20130101) Original (OR) Class G01N 33/54393 (20130101) G01N 2291/0255 (20130101) G01N 2291/0256 (20130101) G01N 2291/0427 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11243368 | Rottle et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Keyport, Washington) |
| INVENTOR(S) | Brandon Rottle (Tacoma, Washington); Mitch Van Epps (Seabeck, Washington); Steven Kyle Denton (Wauna, Washington); Robert Lutes (Silverdale, Washington) |
| ABSTRACT | A fiber optic cable clamp has two identical halves that snap together forming the clamp. The clamp can be made of thermoplastic materials and designed to permit stacking of multiple clamps without damaging the cables. |
| FILED | Wednesday, April 22, 2020 |
| APPL NO | 16/873502 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 3/10 (20130101) F16L 3/1025 (20130101) Optical Elements, Systems, or Apparatus G02B 6/3616 (20130101) G02B 6/4471 (20130101) Original (OR) Class Installation of Electric Cables or Lines, or of Combined Optical and Electric Cables or Lines H02G 3/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11244003 | Abeloe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Centauri, LLC (Chantilly, California) |
| ASSIGNEE(S) | CENTAURI, LLC (Chantilly, Virginia) |
| INVENTOR(S) | Kenneth A. Abeloe (Carlsbad, California); Dennis Hsu (San Diego, California) |
| ABSTRACT | Systems and methods for full motion video search are provided. In one aspect, a method includes receiving one or more search terms. The search terms include one or more of a characterization of the amount of man-made features in a video image and a characterization of the amount of natural features in the video image. The method further includes searching a full motion video database based on the one or more search terms. |
| FILED | Monday, November 04, 2019 |
| APPL NO | 16/673720 |
| ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 16/113 (20190101) G06F 16/783 (20190101) G06F 16/7837 (20190101) G06F 16/7847 (20190101) G06F 16/7867 (20190101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00637 (20130101) G06K 9/00718 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11244050 | Nataraj et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mayachitra, Inc. (Santa Barbara, California) |
| ASSIGNEE(S) | Mayachitra, Inc. (Santa Barbara, California) |
| INVENTOR(S) | Lakshmanan Nataraj (Goleta, California); Bangalore S. Manjunath (Santa Barbara, California); Shivkumar Chandrasekaran (Santa Barbara, California) |
| ABSTRACT | Methods, systems and computer programs are presented for classifying malware using audio signal processing. One method includes an operation for converting a non-audio data file to an audio signal. Audio features are extracted from the audio signal and are used to classify the non-audio data file. |
| FILED | Monday, December 03, 2018 |
| APPL NO | 16/207586 |
| ART UNIT | 2433 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/55 (20130101) G06F 21/56 (20130101) G06F 21/57 (20130101) G06F 21/562 (20130101) G06F 21/564 (20130101) G06F 21/565 (20130101) Original (OR) Class G06F 21/566 (20130101) G06F 2221/034 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11244160 | Bushmitch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Dennis Bushmitch (Somerset, New Jersey); Michael Badger (Ocean Grove, New Jersey) |
| ABSTRACT | Various embodiments associated with a composite image are described. In one embodiment, a handheld device comprises a launch component configured to cause a launch of a projectile. The projectile is configured to capture a plurality of images. Individual images of the plurality of images are of different segments of an area. The system also comprises an image stitch component configured to stitch the plurality of images into a composite image. The composite image is of a higher resolution than a resolution of individual images of the plurality of images. |
| FILED | Friday, September 23, 2016 |
| APPL NO | 15/273924 |
| ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/08 (20130101) B64C 2201/123 (20130101) B64C 2201/127 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0063 (20130101) Original (OR) Class G06K 9/00771 (20130101) G06K 2009/2045 (20130101) Image Data Processing or Generation, in General G06T 3/4038 (20130101) G06T 3/4053 (20130101) G06T 5/50 (20130101) G06T 7/33 (20170101) G06T 7/38 (20170101) G06T 11/60 (20130101) G06T 2207/10032 (20130101) G06T 2207/20221 (20130101) G06T 2207/30181 (20130101) G06T 2207/30212 (20130101) Pictorial Communication, e.g Television H04N 5/28 (20130101) H04N 5/2624 (20130101) H04N 5/23238 (20130101) H04N 5/23293 (20130101) H04N 7/185 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11245157 | Winter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INNOSENSE LLC (Torrance, California) |
| ASSIGNEE(S) | INNOSENSE LLC (Torrance, California) |
| INVENTOR(S) | Raymond Winter (Riverside, California); Maksudul M. Alam (Glendora, California); Uma Sampathkumaran (Torrance, California); John Abolencia (Los Angeles, California) |
| ABSTRACT | Methods for producing ceramic films Yttria Stabilized Zirconia (3YSZ) and aluminum titanate (Al2TiO5), and the physical properties of these films are described. The films produced have thicknesses and integrity suitable for handling and corrosion resistance to electrolytes, porosity, ion permeability and electrical resistivity suitable for use as separators between positive and negative layers for forming electrical batteries, particularly lithium batteries. |
| FILED | Thursday, February 28, 2019 |
| APPL NO | 16/289026 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/052 (20130101) H01M 10/0561 (20130101) H01M 10/0563 (20130101) H01M 10/0587 (20130101) H01M 10/4235 (20130101) H01M 50/403 (20210101) H01M 50/431 (20210101) Original (OR) Class H01M 50/449 (20210101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11245330 | Giuliano et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | David M. Giuliano (Cambridge, Massachusetts); David J. Perreault (Cambridge, Massachusetts); Robert C. N. Pilawa-Podgurski (Cambridge, Massachusetts) |
| ABSTRACT | A converter circuit and related technique for providing high power density power conversion includes a reconfigurable switched capacitor transformation stage coupled to a magnetic converter (or regulation) stage. The circuits and techniques achieve high performance over a wide input voltage range or a wide output voltage range. The converter can be used, for example, to power logic devices in portable battery operated devices. |
| FILED | Monday, June 29, 2020 |
| APPL NO | 16/915051 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/007 (20210501) H02M 3/07 (20130101) H02M 3/155 (20130101) H02M 3/158 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11245387 | Grout |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kevin Grout (Chandler, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Kevin Grout (Chandler, Arizona) |
| ABSTRACT | A system for generating an RFPWM signal comprises a delta sigma modulator having a plurality of outputs, a phase-locked loop comprising a plurality of phase quantization outputs, at least one multiplexer having a plurality of signal inputs, a plurality of selector inputs, and at least one output, the signal inputs communicatively connected to the phase quantization outputs of the phase-locked loop and the selector inputs electrically connected to the outputs of the delta sigma modulator, and a driver having an input communicatively connected to the output of the multiplexer and an output generating an RFPWM signal. A method of generating an RFPWM signal is also described. |
| FILED | Thursday, January 21, 2021 |
| APPL NO | 17/154437 |
| ART UNIT | 2849 — Electrical Circuits and Systems |
| CURRENT CPC | Pulse Technique H03K 3/012 (20130101) Original (OR) Class H03K 3/017 (20130101) H03K 19/20 (20130101) Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses H03L 7/08 (20130101) Coding; Decoding; Code Conversion in General H03M 3/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11245743 | Mitchell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Architecture Technology Corporation (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Architecture Technology Corporation (Minneapolis, Minnesota) |
| INVENTOR(S) | Tyler J. Mitchell (Ithaca, New York); Judson Powers (Ithaca, New York); Scott Aloisio (Willseyville, New York); Matthew A. Stillerman (Ithaca, New York); Valentino Felipe (Campbell, California) |
| ABSTRACT | In general, this disclosure describes media stream transmission techniques for a computing device. The computing device may capture an image of a local background environment. The computing device may record a first media stream that includes at least a portion of the image of the background environment and at least one movement of at least one object through the background environment. The computing device may remove the image of the background environment from the first media stream to create a second media stream that includes the movement of the object without the image of the background environment. The computing device may determine a bandwidth of a network over which the second media stream will be transmitted and perform further alterations to the second media stream if the current bandwidth is less than a bandwidth threshold level in order to reduce the bandwidth needed to transmit the second media stream. |
| FILED | Friday, September 25, 2020 |
| APPL NO | 17/032454 |
| ART UNIT | 2445 — Computer Networks |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/194 (20170101) G06T 2207/10021 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/67 (20180101) Transmission of Digital Information, e.g Telegraphic Communication H04L 47/801 (20130101) H04L 65/80 (20130101) Original (OR) Class H04L 65/601 (20130101) H04L 65/4084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11241014 | Finn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia); M. G. Finn (Atlanta, Georgia); Jennifer Marie Beveridge (Atlanta, Georgia); Allison Geoghan Aioub (Atlanta, Georgia); Zhishuai Geng (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | M. G. Finn (Atlanta, Georgia); Jennifer Marie Beveridge (Atlanta, Georgia); Allison Geoghan Aioub (Atlanta, Georgia); Zhishuai Geng (Atlanta, Georgia) |
| ABSTRACT | Disclosed are antimicrobial articles and surfaces, as well as methods of making such articles and surfaces. |
| FILED | Wednesday, May 31, 2017 |
| APPL NO | 16/305534 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/10 (20130101) A01N 25/10 (20130101) A01N 33/12 (20130101) A01N 43/40 (20130101) A01N 43/40 (20130101) A01N 43/46 (20130101) A01N 43/90 (20130101) Original (OR) Class Heterocyclic Compounds C07D 495/08 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/32 (20130101) C08F 120/60 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241380 | Freeman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | William Freeman (Del Mar, California); Michael J. Sailor (La Jolla, California); Lingyun Cheng (San Diego, California); Frederique Cunin (Montpellier, France); Emily Anglin (San Diego, California); Yang Yang Li (Hong Kong, China Hong Kong) |
| ABSTRACT | A minimally invasive controlled drug delivery system for delivering a particular drug or drugs to a particular location of the eye, the system including a porous film template having pores configured and dimensioned to at least partially receive at least one drug therein, and wherein the template is dimensioned to be delivered into or onto the eye. |
| FILED | Monday, November 06, 2017 |
| APPL NO | 15/804856 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/0017 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) Original (OR) Class A61K 9/0051 (20130101) A61K 9/1611 (20130101) A61K 9/7007 (20130101) A61K 31/573 (20130101) A61K 47/24 (20130101) A61K 47/26 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241671 | Petruska et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Melissa A. Petruska (Newtown, Connecticut); Trevor E. James (Plantsville, Connecticut); James D. Carruthers (Reno, Nevada); Peter C. Van Buskirk (Newtown, Connecticut); Jeffrey F. Roeder (Brookfield, Connecticut) |
| ASSIGNEE(S) | Sonata Scientific LLC (Danbury, Connecticut) |
| INVENTOR(S) | Melissa A. Petruska (Newtown, Connecticut); Trevor E. James (Plantsville, Connecticut); James D. Carruthers (Reno, Nevada); Peter C. Van Buskirk (Newtown, Connecticut); Jeffrey F. Roeder (Brookfield, Connecticut) |
| ABSTRACT | Monolithic composite photocatalysts for fluid purification, chemical transformations, and surface sterilization are disclosed. The monolithic composite photocatalysts comprise a photoactive nanocrystal component and a non-photoactive porous support. Photocatalytic fluid purification systems that contact an impurity-containing fluid with the subject monolithic composite photocatalysts are also disclosed. |
| FILED | Tuesday, November 12, 2019 |
| APPL NO | 16/680495 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/10 (20130101) A61L 2/16 (20130101) A61L 2/084 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/063 (20130101) Original (OR) Class B01J 35/004 (20130101) B01J 35/04 (20130101) B01J 35/006 (20130101) B01J 35/08 (20130101) B01J 35/023 (20130101) B01J 35/1014 (20130101) B01J 35/1019 (20130101) B01J 35/1023 (20130101) B01J 35/1061 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 35/00 (20130101) B82Y 40/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241681 | Veige et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Adam S. Veige (Gainesville, Florida); Stella Almeida Gonsales (Gainesville, Florida) |
| ABSTRACT | A tetraanionic OCO pincer ligand metal-oxo-alkylidene complex is prepared from a trianionic pincer ligand supported metal-alkylidyne. The metal can be tungsten or other group 5-7 transition metal. The tetraanionic pincer ligand metal-oxo-alkylidene complex, a trianionic OCO pincer ligand metal complex, or a trianionic ONO pincer ligand metal complex can be used to polymerize cycloalkenes. The poly(cycloalkene)s are predominantly cis-alkene macrocyclics. |
| FILED | Monday, March 02, 2020 |
| APPL NO | 16/806054 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/223 (20130101) Original (OR) Class B01J 31/2243 (20130101) B01J 31/2265 (20130101) B01J 31/2286 (20130101) B01J 2231/14 (20130101) B01J 2231/543 (20130101) B01J 2531/66 (20130101) B01J 2531/0244 (20130101) B01J 2540/10 (20130101) B01J 2540/225 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 11/00 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 4/69 (20130101) C08F 4/78 (20130101) C08F 4/69206 (20130101) C08F 32/04 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/08 (20130101) C08G 2261/13 (20130101) C08G 2261/418 (20130101) C08G 2261/3324 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242248 | Groves et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | John T. Groves (Princeton, New Jersey); Roy Xiao (Princeton, New Jersey) |
| ABSTRACT | Methods, kits, cartridges, and compounds related to generating chlorine dioxide by exposing ClO2− to at least one of an iron porphyrin catalyst or an iron porphyrazine catalyst are described. |
| FILED | Wednesday, May 01, 2019 |
| APPL NO | 16/400277 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/18 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/26 (20130101) B01J 31/183 (20130101) B01J 31/1815 (20130101) B01J 31/2295 (20130101) B01J 2531/025 (20130101) B01J 2531/842 (20130101) Non-metallic Elements; Compounds Thereof; C01B 11/024 (20130101) Original (OR) Class Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/76 (20130101) C02F 2103/023 (20130101) C02F 2303/04 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/025 (20130101) Production of Cellulose by Removing Non-cellulose Substances From Cellulose-containing Materials; Regeneration of Pulping Liquors; Apparatus Therefor D21C 9/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242290 | Faber et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Katherine T. Faber (Pasadena, California); Julia A. Kornfield (Pasadena, California); Noriaki Arai (Pasadena, California); Orland Bateman (Pasadena, California); Rustem F. Ismagilov (Pasadena, California) |
| ABSTRACT | Provided herein are methods for making a freeze-cast material having a internal structure, the methods comprising steps of: determining the internal structure of the material, the internal structure having a plurality of pores, wherein: each of the plurality of pores has directionality; and the step of determining comprises: selecting a temperature gradient and a freezing front velocity to obtain the determined internal structure based on the selected temperature gradient and the selected freezing front velocity; directionally freezing a liquid formulation to form a frozen solid, the step of directionally freezing comprising: controlling the temperature gradient and the freezing front velocity to match the selected temperature gradient and the selected freezing front velocity during directionally freezing; wherein the liquid formulation comprises at least one solvent and at least one dispersed species; and subliming the at least one solvent out of the frozen solid to form the material. |
| FILED | Friday, August 23, 2019 |
| APPL NO | 16/549954 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 67/0051 (20130101) B01D 69/02 (20130101) B01D 71/024 (20130101) B01D 2325/021 (20130101) B01D 2325/26 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 35/04 (20130101) B01J 35/1071 (20130101) B01J 35/1076 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 38/007 (20130101) C04B 38/0038 (20130101) C04B 38/0054 (20130101) C04B 38/0093 (20130101) C04B 38/0605 (20130101) Original (OR) Class Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/14 (20130101) H01B 1/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242296 | Dussault et al. |
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| FUNDED BY |
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| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska) |
| INVENTOR(S) | Patrick H. Dussault (Lincoln, Nebraska); Andrew Olson (Lincoln, Nebraska) |
| ABSTRACT | Disclosed herein is a method of reducing or disproportionating peroxide, comprising combining an organic chalcogenide, an iron salt, and the peroxide in the presence of an additional reductant, which can be the organic chalcogenide. The method can be used to, e.g., prepare alcohols from peroxides and to disproportionate hydrogen peroxide into water and oxygen. |
| FILED | Wednesday, July 17, 2019 |
| APPL NO | 16/514423 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 41/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242363 | Veige et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Adam S. Veige (Gainesville, Florida); Vineet K. Jakhar (Gainesville, Florida); Muhammad Tariq Jan (Khyber Paktunkhwa, Pakistan) |
| ABSTRACT | Disclosed are to metallocyclopropene complexes, methods of making same, methods for ring expansion metathesis polymerization, and polymers prepared by the methods for ring expansion metathesis polymerization. |
| FILED | Friday, November 30, 2018 |
| APPL NO | 16/767697 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 11/00 (20130101) Original (OR) Class Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 132/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242367 | Lawrence et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Silk Technologies, Ltd. (Plymouth, Minnesota) |
| ASSIGNEE(S) | Silk Technologies, Ltd. (Plymouth, Minnesota) |
| INVENTOR(S) | Brian D. Lawrence (Tampa, Florida); David W. Infanger (Maple Grove, Minnesota) |
| ABSTRACT | Described herein are methods for reducing inflammation by administration of an effective amount of silk-derived proteins (SDP) or a fraction thereof to a subject having an inflammatory condition. The methods include the treatment of inflammatory conditions and wounds, including corneal wounds, comprising the topical administration of an effective amount of SDP material as described herein. |
| FILED | Saturday, August 12, 2017 |
| APPL NO | 16/324844 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/14 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 38/00 (20130101) A61K 38/012 (20130101) A61K 47/02 (20130101) A61K 47/10 (20130101) A61K 47/26 (20130101) A61K 47/34 (20130101) A61K 47/38 (20130101) A61K 47/42 (20130101) A61K 47/183 (20130101) Peptides C07K 14/43586 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11243029 | Strongrich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Andrew Strongrich (West Lafayette, Indiana); Alina Alexeenko (West Lafayette, Indiana) |
| ABSTRACT | A non-invasive method to monitor and control of lyophilization of a frozen product solution to remove solvents is disclosed which includes installing one or more wireless pressure sensors configured to fit into a lyophilization vial tray disposed in a lyophilization chamber having a plurality of product vials, wherein the wireless pressure are distributed among the product vials being lyophilized thereby providing spatial pressure variations, collecting the spatial pressure information from said wireless pressure sensors, calculating sublimation rate of the solution, and adjusting pressure and/or temperature within the lyophilization chamber such that the calculated sublimation rate stays within a predetermined envelope. |
| FILED | Monday, April 27, 2020 |
| APPL NO | 16/859835 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Drying Solid Materials or Objects by Removing Liquid Therefrom F26B 5/06 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11243079 | Das |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | KUTZTOWN UNIVERSITY OF PENNSYLVANIA (Kutztown, Pennsylvania) |
| ASSIGNEE(S) | Kutztown University of Pennsylvania (Kutztown, Pennsylvania) |
| INVENTOR(S) | Kunal Das (Reading, Pennsylvania) |
| ABSTRACT | Embodiments relate to a sensor system configured to detect physical rotation, entire or relative, of one or more objects and/or their environment and/or proximity of a magnetic field, by measuring the degree of localization of a medium trapped in a ring-shaped artificial lattice. The lattice structure can be configured to comprise of lattice sites distributed with a lattice period around an azimuth of a closed ring. The site depths of the plurality of lattice sites can be configured to be modulated with a modulation period different from the lattice period to affect the onsite energies of each lattice site and the eigenstates of the system. Physical rotation of the sensor and/or the proximity of magnetic field will alter the localization properties so as to cause the degree of localization of the medium to change (e.g., the medium becomes more confined in space or more spread out in space). |
| FILED | Tuesday, November 12, 2019 |
| APPL NO | 16/617894 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/58 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/032 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11243295 | Spuler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University Corporation for Atmospheric Research (Boulder, Colorado); Montana State University (Bozeman, Montana); NASA Langley Research Center (Hampton, Virginia) |
| ASSIGNEE(S) | University Corporation for Atmospheric Research (Boulder, Colorado); Montana State University (Bozeman, Montana); NASA Langley Research Center (Hampton, Virginia) |
| INVENTOR(S) | Scott M. Spuler (Westminster, Colorado); Kevin S. Repasky (Bozeman, Montana); Amin R. Nehrir (Yorktown, Virginia) |
| ABSTRACT | A filter for a micropulse differential absorption LIDAR is provided. The filter comprises an etalon including a free spectral range substantially the same as a difference between a first laser wavelength and a second laser wavelength, the etalon further including a finesse providing substantial background noise suppression and substantially constant transmission of the first laser wavelength and the second laser wavelength over a predetermined range of wavelengths, and a first filter having a first filter bandpass selected to include the first laser wavelength and the second laser wavelength. |
| FILED | Thursday, June 28, 2018 |
| APPL NO | 16/022320 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/538 (20130101) G01N 2021/1795 (20130101) G01N 2021/4709 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/484 (20130101) G01S 7/4812 (20130101) G01S 7/4814 (20130101) Original (OR) Class G01S 7/4816 (20130101) G01S 17/18 (20200101) G01S 17/95 (20130101) Technologies for Adaptation to Climate Change Y02A 90/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11243419 | Cardenas et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Jaime Cardenas (Rochester, New York); Yi Zhang (Rochester, New York) |
| ABSTRACT | A deposition method for manufacturing an active electro-optic layer includes providing a substrate or a base layer; and applying an electric field across a silicon nitride layer as it is being deposited on the substrate or the base layer to cause a poling of a deposited layer. Alternative methods for poling an active electro-optic layer and an electro-optical device are also described. |
| FILED | Thursday, October 17, 2019 |
| APPL NO | 16/655816 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/50 (20130101) C23C 16/345 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/035 (20130101) Original (OR) Class G02F 2202/20 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0217 (20130101) H01L 21/02274 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11243559 | Taskin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania); University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Baris Taskin (Philadelphia, Pennsylvania); Ragh Kuttappa (Philadelphia, Pennsylvania); Selcuk Kose (Tampa, Florida) |
| ABSTRACT | Modern integrated circuits have an increasing need for various levels of both supply voltage (V) and operating frequency (f) available at fine spatial and temporal granularity. This work introduces a solution that provides a number and quality of locally distributed V/f domains through FOPAC. Opportunistically sharing design resources and features between multi-phase voltage regulators (MPVRs) and resonant rotary clocks (ReRoCs) enabling i) the scalability to hundreds of domains, ii) fast switching times for both voltage and frequency, leading to temporal flexibility, and iii) locally distributed designs, leading to spatial flexibility. |
| FILED | Friday, May 29, 2020 |
| APPL NO | 16/887056 |
| ART UNIT | 2849 — Optics |
| CURRENT CPC | Systems for Regulating Electric or Magnetic Variables G05F 1/10 (20130101) Electric Digital Data Processing G06F 1/10 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/66 (20130101) Pulse Technique H03K 3/012 (20130101) H03K 3/0315 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11243881 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Rujia Wang (Chicago, Illinois); Jun Yang (Pittsburgh, Pennsylvania); YouTao Zhang (Pittsburgh, Pennsylvania) |
| ABSTRACT | An apparatus including (i) a processor including a plurality of main buffer on board (BOB) memory controllers (MCs) and a secure engine, (ii) a plurality of simple BOB MCs, (iii) a secure delegator, and (iv) a plurality of memory modules. The secure delegator coupled to a first main BOB MC and a first simple BOB MC creates a secure channel. A second main BOB MC coupled to a second simple BOB MC creates a non-secure channel. The plurality of main BOB MCs, the secure engine and the secure delegator are provided within a trusted computing base (TCB) of the apparatus and the plurality of simple BOB MCs and the plurality of memory modules are provided outside the TCB. The secure delegator is configured to: (i) secure communication between the first main BOB MC and the secure delegator, and (ii) perform Path ORAM accesses to the plurality of memory modules. |
| FILED | Tuesday, July 30, 2019 |
| APPL NO | 16/526108 |
| ART UNIT | 2133 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 9/5016 (20130101) G06F 12/0638 (20130101) Original (OR) Class G06F 12/0815 (20130101) G06F 12/1408 (20130101) G06F 13/1673 (20130101) G06F 2212/1021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11244110 | Herr et al. |
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| FUNDED BY |
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| APPLICANT(S) | BLACKBOILER, INC. (Arlington, Virginia) |
| ASSIGNEE(S) | BLACKBOILER, INC. (Arlington, Virginia) |
| INVENTOR(S) | Jonathan Herr (Washington, District of Columbia); Daniel Edward Simonson (Arlington, Virginia); Daniel P. Broderick (Arlington, Virginia) |
| ABSTRACT | A method for suggesting revisions to a document-under-analysis from a seed database, the seed database including a plurality of original texts each respectively associated with one of a plurality of final texts, the method for suggesting revisions including selecting a statement-under-analysis (“SUA”), selecting a first original text of the plurality of original texts, determining a first edit-type classification of the first original text with respect to its associated final text, generating a first similarity score for the first original text based on the first edit-type classification, the first similarity score representing a degree of similarity between the SUA and the first original text, selecting a second original text of the plurality of original texts, determining a second edit-type classification of the second original text with respect to its associated final text, generating a second similarity score for the second original text based on the second edit-type classification, the second similarity score representing a degree of similarity between the SUA and the second original text, selecting a candidate original text from one of the first original text and the second original text, and creating an edited SUA (“ESUA”) by modifying a copy of the first SUA consistent with a first candidate final text associated with the first candidate original text. |
| FILED | Monday, July 13, 2020 |
| APPL NO | 16/927324 |
| ART UNIT | 2144 — Graphical User Interface and Document Processing |
| CURRENT CPC | Electric Digital Data Processing G06F 16/35 (20190101) G06F 16/36 (20190101) G06F 16/383 (20190101) G06F 40/45 (20200101) G06F 40/131 (20200101) G06F 40/137 (20200101) G06F 40/166 (20200101) G06F 40/169 (20200101) G06F 40/194 (20200101) G06F 40/253 (20200101) Original (OR) Class G06F 40/268 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11244189 | Fathi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Pointivo, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | POINTIVO, INC. (Atlanta, Georgia) |
| INVENTOR(S) | Habib Fathi (Atlanta, Georgia); Miguel M. Serrano (Marietta, Georgia); Bradden John Gross (Atlanta, Georgia); Daniel L. Ciprari (Atlanta, Georgia) |
| ABSTRACT | Examples of various method and systems are provided for information extraction from scene information. 2D image information can be generated from 2D images of the scene that are overlapping at least part of one or more object(s). The 2D image information can be combined with 3D information about the scene incorporating at least part of the object(s) to generate projective geometry information. Clustered 3D information associated with the object(s) can be generated by partitioning and grouping 3D data points present in the 3D information. The clustered 3D information can be used to provide, e.g., measurement information, dimensions, geometric information, and/or topological information about the object(s). Segmented 2D information can also be generated from the 2D image information. Validated 2D and 3D information can be produced by cross-referencing between the projective geometry information, clustered 3D information, and/or segmented 2D image information, and used to label the object(s) in the scene. |
| FILED | Friday, March 13, 2020 |
| APPL NO | 16/818814 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00201 (20130101) G06K 9/00208 (20130101) G06K 9/342 (20130101) Original (OR) Class G06K 9/00664 (20130101) G06K 9/6218 (20130101) G06K 2209/40 (20130101) Image Data Processing or Generation, in General G06T 7/55 (20170101) G06T 17/00 (20130101) G06T 2207/10028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11244309 | Bentov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Iddo Bentov (Ithaca, New York); Ari Juels (New York, New York); Fan Zhang (Ithaca, New York); Philip Daian (New York, New York); Lorenz Breidenbach (Zurich, Switzerland) |
| ABSTRACT | An apparatus in an illustrative embodiment comprises a processing platform that includes one or more processing devices each comprising a processor coupled to a memory. The processing platform is configured to communicate over at least one network with one or more additional sets of processing devices associated with at least a first blockchain-based cryptocurrency system. Each of at least a subset of the one or more processing devices of the processing platform comprises a trusted execution environment, such as a secure enclave. The processing platform is further configured to release from the trusted execution environment of a given one of the one or more processing devices of the processing platform a first blockchain transaction on the first blockchain-based cryptocurrency system, and to condition release of a second blockchain transaction relating to the first blockchain transaction on receipt of at least a specified threshold amount of evidence of confirmation of the first blockchain transaction on the first blockchain-based cryptocurrency system. |
| FILED | Wednesday, November 21, 2018 |
| APPL NO | 16/198223 |
| ART UNIT | 3685 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 20/027 (20130101) G06Q 20/065 (20130101) G06Q 20/389 (20130101) G06Q 20/405 (20130101) G06Q 20/38215 (20130101) Original (OR) Class G06Q 2220/00 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0897 (20130101) H04L 2209/38 (20130101) H04L 2209/56 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11241752 | Goeke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Ronald S. Goeke (Los Ranchos, New Mexico); Charles A. Walker (Albuquerque, New Mexico); Juan A. Romero (Bayfield, Colorado) |
| ABSTRACT | Nanometers thick conformal coatings deposited by atomic-layer deposition (ALD) onto the metal surface of an active braze joint modifies the surface chemistry to eliminate excess braze filler metal flow. Unlike other means used to prevent braze filler metal runout, the thin ALD coating does not hinder next assembly processes, does not require post-braze cleaning, and does not alter the base material mechanical properties. |
| FILED | Friday, May 10, 2019 |
| APPL NO | 16/409087 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 1/20 (20130101) Original (OR) Class B23K 2103/52 (20180801) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/403 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11241932 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Evelyn N Wang (Cambridge, Massachusetts); Hyunho Kim (Cambridge, Massachusetts); Xiansen Li (Lexington, Kentucky); Shankar Narayan (Chestnut Hill, Massachusetts); Sameer R. Rao (Cambridge, Massachusetts); Ari Samuel Umans (Cambridge, Massachusetts); Sungwoo Yang (Cambridge, Massachusetts) |
| ABSTRACT | An adsorption system can be used as part of a climate control system in a vehicle or in any other space requiring heating or cooling. The adsorbent system can include an enclosure, a plurality of layers arranged in a stack inside the enclosure, and a vapor channel inside the enclosure. |
| FILED | Monday, December 24, 2018 |
| APPL NO | 16/231865 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Arrangements of Heating, Cooling, Ventilating or Other Air-treating Devices Specially Adapted for Passenger or Goods Spaces of Vehicles B60H 1/22 (20130101) B60H 1/00278 (20130101) B60H 1/00392 (20130101) B60H 1/00492 (20130101) Original (OR) Class B60H 1/3201 (20130101) B60H 1/3202 (20130101) B60H 1/32014 (20190501) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 17/08 (20130101) F25B 37/00 (20130101) F25B 2315/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242314 | Zhou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dong Zhou (St. Louis, Missouri); Wenhua Chu (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Dong Zhou (St. Louis, Missouri); Wenhua Chu (St. Louis, Missouri) |
| ABSTRACT | The present disclosure relates to the methods for the preparation of reactive [F-18]fluoride in a form of [F-18]sulfonyl fluoride suitable for efficient radiolabeling without an azeotropic evaporation step by the use of anion exchange resin and sulfonyl chloride, and its applications in the manufacturing of PET radiopharmaceuticals. |
| FILED | Wednesday, January 11, 2017 |
| APPL NO | 15/403954 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 59/001 (20130101) C07B 59/002 (20130101) C07B 59/005 (20130101) C07B 2200/05 (20130101) Acyclic or Carbocyclic Compounds C07C 45/63 (20130101) C07C 45/63 (20130101) C07C 47/55 (20130101) C07C 67/307 (20130101) C07C 67/307 (20130101) C07C 69/76 (20130101) C07C 247/04 (20130101) C07C 303/22 (20130101) C07C 303/22 (20130101) C07C 303/22 (20130101) C07C 303/22 (20130101) C07C 309/86 (20130101) C07C 309/87 (20130101) C07C 309/89 (20130101) C07C 315/04 (20130101) Original (OR) Class Heterocyclic Compounds C07D 207/09 (20130101) C07D 213/52 (20130101) C07D 213/71 (20130101) C07D 233/91 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 3/02 (20130101) C07H 19/06 (20130101) Steroids C07J 1/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242432 | Coates et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Geoffrey W. Coates (Lansing, New York); Kristina M. Hugar (Ithaca, New York) |
| ABSTRACT | The invention provides: imidazole and imidazolium compounds of formulas (I) and (II): polymers containing a plurality of imidazolium-containing repeating units of formula (III′): and membranes and devices comprising the polymers. Also provided are methods of making the inventive compounds and polymers. |
| FILED | Thursday, April 14, 2016 |
| APPL NO | 15/566595 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Separation B01D 71/44 (20130101) B01D 71/62 (20130101) Heterocyclic Compounds C07D 233/58 (20130101) C07D 233/60 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/30 (20130101) C08F 8/30 (20130101) C08F 12/26 (20130101) C08F 26/06 (20130101) C08F 126/06 (20130101) C08F 210/14 (20130101) C08F 210/14 (20130101) C08F 212/14 (20130101) C08F 212/36 (20130101) C08F 214/16 (20130101) C08F 214/16 (20130101) C08F 226/06 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/02 (20130101) C08G 61/04 (20130101) Original (OR) Class C08G 61/06 (20130101) C08G 61/08 (20130101) C08G 2261/148 (20130101) C08G 2261/149 (20130101) C08G 2261/418 (20130101) C08G 2261/516 (20130101) C08G 2261/724 (20130101) C08G 2261/1424 (20130101) C08G 2261/3322 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/2231 (20130101) C08J 2323/18 (20130101) C08J 2323/36 (20130101) Compositions of Macromolecular Compounds C08L 25/18 (20130101) C08L 71/02 (20130101) C08L 2203/20 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/1023 (20130101) H01M 50/411 (20210101) H01M 2300/0082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242544 | Donohue et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Timothy James Donohue (Middleton, Wisconsin); Matthew Scarborough (Madison, Wisconsin); Daniel Noguera (Madison, Wisconsin) |
| ABSTRACT | Microbiome compositions and uses thereof. The microbiome compositions include a set of microbes. The sets of microbes contain members of Lactobacillaceae, Eubacteriaceae, Lachnospiraceae, and Coriobacteriaceae. The number of individual physical microbes in the set constitutes a certain percentage of the total number of individual physical microbes in the microbiome composition. The microbiome compositions can be used for producing medium-chain fatty acids from organic substrates through anaerobic fermentation in a medium. The medium can include lignocellulosic stillage. |
| FILED | Thursday, June 06, 2019 |
| APPL NO | 16/433639 |
| ART UNIT | 1699 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/205 (20210501) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/6409 (20130101) Original (OR) Class C12P 2203/00 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/225 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242587 | Shyam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); FCA US LLC (Auburn Hills, Michigan); NEMAK USA, Inc. (Dickson, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); FCA US LLC (Auburn Hills, Michigan); Nemak USA, Inc. (Dickson, Tennessee) |
| INVENTOR(S) | Amit Shyam (Knoxville, Tennessee); James A. Haynes (Knoxville, Tennessee); Adrian S. Sabau (Knoxville, Tennessee); Dongwon Shin (Knoxville, Tennessee); Yukinori Yamamoto (Knoxville, Tennessee); Christopher R. Glaspie (Rochester Hills, Michigan); Jose A. Gonzalez-Villarreal (Monterrey, Mexico); Seyed Mirmiran (Auburn Hills, Michigan); Andres F. Rodriguez-Jasso (Garcia, Mexico) |
| ABSTRACT | The present disclosure concerns embodiments of aluminum alloy compositions exhibiting superior microstructural stability and strength at high temperatures. The disclosed aluminum alloy compositions comprise particular combinations of components that contribute the ability of the alloys to exhibit improved microstructural stability and hot tearing resistance as compared to conventional alloys. Also disclosed herein are embodiments of methods of making and using the alloys. |
| FILED | Friday, May 12, 2017 |
| APPL NO | 15/594434 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 21/007 (20130101) Alloys C22C 1/06 (20130101) C22C 1/026 (20130101) C22C 21/12 (20130101) C22C 21/14 (20130101) C22C 21/16 (20130101) C22C 21/18 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/057 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242756 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | James Zhang (Simpsonville, South Carolina); John McConnell Delvaux (Fountain Inn, South Carolina) |
| ABSTRACT | A coating is applied to a base material. The coating comprises a viscoelastic layer having a surface in which cavities are formed; and a constraint layer. The viscoelastic layer is disposed on the base material, and the constraint layer is disposed on, and partially bonded, at an interface, to the viscoelastic layer over the surface in which the cavities are formed. The cavities are filled with particles configured for vibration and frictional interaction at the partially bonded interface between the partially bonded viscoelastic layer and the constraint layer. A turbine blade having an airfoil with the subject coating is also provided. |
| FILED | Monday, May 04, 2020 |
| APPL NO | 16/865999 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 9/041 (20130101) B32B 2307/51 (20130101) B32B 2603/00 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/16 (20130101) Original (OR) Class F01D 5/225 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/307 (20130101) F05D 2260/96 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242843 | Anderson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | 247Solar Inc. (Great Falls, Virginia) |
| ASSIGNEE(S) | 247Solar Inc. (Great Falls, Virginia) |
| INVENTOR(S) | Bruce N. Anderson (Great Falls, Virginia); William Dean Treece (La Mesa, California); Dan Brown (Lebanon, New Hampshire); Florian Bennhold (Osnabruk, Germany); Christoph Hilgert (Odenthal, Germany) |
| ABSTRACT | Inventive concentrated solar power systems using solar receivers, and related devices and methods, are generally described. Low pressure solar receivers are provided that function to convert solar radiation energy to thermal energy of a working fluid, e.g., a working fluid of a power generation or thermal storage system. In some embodiments, low pressure solar receivers are provided herein that are useful in conjunction with gas turbine based power generation systems. |
| FILED | Thursday, March 21, 2019 |
| APPL NO | 16/361074 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 1/04 (20130101) F02C 1/08 (20130101) Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 6/06 (20130101) Original (OR) Class F03G 6/064 (20130101) Solar Heat Collectors; Solar Heat Systems F24S 10/40 (20180501) F24S 10/80 (20180501) F24S 20/20 (20180501) F24S 23/79 (20180501) F24S 70/12 (20180501) F24S 80/20 (20180501) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 19/04 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/40 (20130101) Y02E 10/44 (20130101) Y02E 10/46 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11243276 | Khitun |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Alexander Khitun (Long Beach, California) |
| ABSTRACT | A magnetic field detector and associated methods are shown. One example of a magnetic field detector uses spin wave interference to detect information about an external magnetic field. |
| FILED | Thursday, September 05, 2019 |
| APPL NO | 16/562171 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/1284 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11243315 | Taleyarkhan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rusi P Taleyarkhan (Lafayette, Indiana) |
| ASSIGNEE(S) | Rusi P. Taleyarkhan (Lafayette, Indiana) |
| INVENTOR(S) | Rusi P Taleyarkhan (Lafayette, Indiana) |
| ABSTRACT | Systems and methods for neutron detection using tensioned metastable fluid detectors, using multi-atom spectroscopy approach. |
| FILED | Thursday, January 30, 2020 |
| APPL NO | 16/776512 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 3/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11243884 | Mashimo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| ASSIGNEE(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| INVENTOR(S) | Susumu Mashimo (Boxborough, Massachusetts); John Kalamatianos (Boxborough, Massachusetts) |
| ABSTRACT | A method of prefetching target data includes, in response to detecting a lock-prefixed instruction for execution in a processor, determining a predicted target memory location for the lock-prefixed instruction based on control flow information associating the lock-prefixed instruction with the predicted target memory location. Target data is prefetched from the predicted target memory location to a cache coupled with the processor, and after completion of the prefetching, the lock-prefixed instruction is executed in the processor using the prefetched target data. |
| FILED | Tuesday, November 13, 2018 |
| APPL NO | 16/190111 |
| ART UNIT | 2138 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 12/0862 (20130101) Original (OR) Class G06F 2212/27 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11245103 | Mikhaylik et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sion Power Corporation (Tucson, Arizona) |
| ASSIGNEE(S) | Sion Power Corporation (Tucson, Arizona) |
| INVENTOR(S) | Yuriy V. Mikhaylik (Tucson, Arizona); Michael G. Laramie (Tucson, Arizona); John Joseph Christopher Kopera (Vail, Arizona) |
| ABSTRACT | An electrode structure and its method of manufacture are disclosed. The disclosed electrode structures may be manufactured by depositing a first release layer on a first carrier substrate. A first protective layer may be deposited on a surface of the first release layer and a first electroactive material layer may then be deposited on the first protective layer. Subsequently, the first carrier substrate may be delaminated from the first release layer. The first release layer may then be removed from the first protective layer by dissolution in an electrolyte. The first protective layer may have a low mean peak to valley surface roughness and/or may be thin. In some embodiments, an interface between the first protective layer and the first electroactive material layer has a low mean peak to valley surface roughness. In some embodiments, a thickness of the first protective layer is greater than a mean peak to valley roughness of the first release layer. In some embodiments, an adhesive strength between the first release layer and the first protective layer is greater than an adhesive strength between the first release layer and the first carrier substrate. |
| FILED | Friday, March 29, 2019 |
| APPL NO | 16/369027 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/13 (20130101) H01M 4/131 (20130101) H01M 4/139 (20130101) H01M 4/0402 (20130101) Original (OR) Class H01M 4/0407 (20130101) H01M 4/0423 (20130101) H01M 4/0428 (20130101) H01M 4/1391 (20130101) H01M 10/052 (20130101) H01M 10/058 (20130101) H01M 10/0565 (20130101) H01M 50/461 (20210101) H01M 2300/0085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11245111 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Bo Yang (Los Angeles, California); G. K. Surya Prakash (Hacienda Heights, California); Robert Aniszfeld (Los Angeles, California); Sri R. Narayan (Arcadia, California); Lena Hoober-Burkhardt (Los Angeles, California); Sankarganesh Krishnamoorthy (Los Angeles, California); Advaith Murali (Los Angeles, California); Archith Nirmalchandar (Los Angeles, California) |
| ABSTRACT | A quinone derivative with a high redox potential that does not undergo Michael addition or proto-desulfonation. This molecule addresses the key issues faced with the positive side material of an aqueous all-organic flow battery. This new molecule is 2,5-dihydroxy-4,6-dimethylbenzene-1,3-disulfonic acid (or the disulfonate salt thereof). This quinone derivative offers good solubility, electrochemical reversibility, and robustness to charge/discharge cycling. Quinones with reduced crossover are also provided. |
| FILED | Tuesday, October 16, 2018 |
| APPL NO | 16/161647 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 303/08 (20130101) C07C 303/08 (20130101) C07C 309/42 (20130101) C07C 309/42 (20130101) C07C 309/43 (20130101) C07C 309/44 (20130101) C07C 2603/24 (20170501) C07C 2603/50 (20170501) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/60 (20130101) H01M 4/368 (20130101) Original (OR) Class H01M 8/08 (20130101) H01M 8/188 (20130101) H01M 2004/028 (20130101) H01M 2008/1095 (20130101) H01M 2300/0002 (20130101) H01M 2300/0082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11245114 | Amine et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Khalil Amine (Oak Brook, Illinois); Ali Abouimrane (Bolingbrook, Illinois) |
| ABSTRACT | A secondary battery including a cathode having a primary cathode active material and an alkaline source material selected from the group consisting of Na2O, Na2O2, Na2S, NaF, NaCl, NaBr, Li2O, Li2O2, Li2S, LiF, LiCl, LiBr, Na2O, Na2O2, Na2S, NaF, NaCl, and a mixture of any two or more thereof; an anode having an anode active material; an electrolyte; and a separator. |
| FILED | Thursday, January 19, 2017 |
| APPL NO | 15/410125 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/485 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) Original (OR) Class H01M 4/5825 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11245330 | Giuliano et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | David M. Giuliano (Cambridge, Massachusetts); David J. Perreault (Cambridge, Massachusetts); Robert C. N. Pilawa-Podgurski (Cambridge, Massachusetts) |
| ABSTRACT | A converter circuit and related technique for providing high power density power conversion includes a reconfigurable switched capacitor transformation stage coupled to a magnetic converter (or regulation) stage. The circuits and techniques achieve high performance over a wide input voltage range or a wide output voltage range. The converter can be used, for example, to power logic devices in portable battery operated devices. |
| FILED | Monday, June 29, 2020 |
| APPL NO | 16/915051 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/007 (20210501) H02M 3/07 (20130101) H02M 3/155 (20130101) H02M 3/158 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11241833 | Gandhiraman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Universities Space Research Association (Mountain View, California) |
| ASSIGNEE(S) | UNIVERSITIES SPACE RESEARCH ASSOCIATION (Columbia, Maryland) |
| INVENTOR(S) | Ramprasad Gandhiraman (Sunnyvale, California); Meyya Meyyappan (Pacifica, California); Jessica E. Koehne (Portola Valley, California) |
| ABSTRACT | A device and method for printing 3D articles including electronic and functional elements including 3D printer and a plasma jet printer based on a dielectric barrier atmospheric pressure plasma jet system in which both printing and in-situ treatment and post-deposition treatment can be carried out to tailor the materials characteristics. Plasma jet printer comprising of electrodes in the nozzle/print head for applying electric field and generating atmospheric plasma that could be used for non-gravity based highly directional printing in any direction. Integration of dielectric barrier plasma printer and plasma treatment jets with the 3D printer increases the capability of embedding high performance electronics in a 3D printed structure aiding in additive manufacturing of functional devices. Ability to use a range of materials for print head assembly including micro machined silicon increases the resolution of the plasma jet printer to sub-micron level. |
| FILED | Thursday, March 09, 2017 |
| APPL NO | 15/454920 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/16 (20130101) B22F 10/00 (20210101) B22F 10/10 (20210101) B22F 12/00 (20210101) B22F 12/00 (20210101) B22F 2202/13 (20130101) B22F 2202/13 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/106 (20170801) B29C 64/188 (20170801) B29C 64/321 (20170801) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) B33Y 50/02 (20141201) B33Y 70/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242134 | Nguyen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as Represented by the Administrator of the NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Nhan Thanh Nguyen (Santa Clara, California); Eric Bi-Wen Ting (Los Altos, California) |
| ABSTRACT | Processes for real-time drag optimization control for aeroelastic wing structures are disclosed. Adaptive reconfiguration of aircraft control surfaces by an online real-time drag optimization control approach to reduce or minimize drag may reduce the amount of fuel that is consumed by the aircraft during flight. The input data may be obtained from sensor information pertaining to the wing deflection and aircraft state information. The optimization approach may compute an optimal solution of the distributed flight control surface deflections that are integrated in a flight path angle flight control system. |
| FILED | Tuesday, May 22, 2018 |
| APPL NO | 15/986794 |
| ART UNIT | 3666 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 9/06 (20130101) B64C 13/18 (20130101) Original (OR) Class Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 5/60 (20170101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242844 | Woodruff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CU Aerospace, LLC (Champaign, Illinois) |
| ASSIGNEE(S) | CU Aerospace, LLC (Champagne, Illinois) |
| INVENTOR(S) | Curtis Woodruff (Savoy, Illinois); Darren King (Champaign, Illinois); Rodney Burton (Champaign, Illinois); David L. Carroll (Champaign, Illinois) |
| ABSTRACT | A Fiber-fed Pulsed Plasma Thruster (FPPT) utilizes a motor to feed PTFE fiber to its discharge region, enabling high PPT propellant throughput and variable exposed fuel area. A highly parallel ceramic capacitor bank lowers system specific mass. Impulse bits (I-bits) from 0.057-0.241 mN-s have been measured on a thrust stand with a specific impulse (Isp) of 900-2400 s, representing an enhancement from state-of-the-art PPT technology. A 1 U (10 cm×10 cm×10 cm, or 1 liter) volume FPPT thruster package will provide 2900-7700 N-s total impulse, enabling 0.6-1.6 km/s delta-V for a 5 kg CubeSat. A 1 U design variation with 590 g propellant enables as much as ˜10,000 N-s and a delta-V of 2 km/s for a 5 kg CubeSat. Increasing the form factor to 2U increases propellant mass to 1.4 kg and delta-V to 10.7 km/s for an 8 kg CubeSat. |
| FILED | Thursday, June 13, 2019 |
| APPL NO | 16/439755 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/405 (20130101) Producing a Reactive Propulsive Thrust, Not Otherwise Provided for F03H 1/0012 (20130101) F03H 1/0031 (20130101) F03H 1/0043 (20130101) F03H 1/0087 (20130101) Original (OR) Class Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/14 (20130101) H05H 1/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11243159 | Palinski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Timothy J. Palinski (Cleveland, Ohio); Gary W. Hunter (Cleveland, Ohio); John Zhang (Cleveland, Ohio) |
| ABSTRACT | A tunable colorimetric sensor/optical filter is based on a lithography-free, asymmetric Fabry-Perot cavity. The sensor has a thin-film structure formed by a lossy, porous nanoplasmonic top film deposited on an actively tunable spacer middle layer, and a reflective base layer (either a metal or semiconductor). The structure is fabricated using wafer-scale PVD processes, and the middle layer responds to the presence of a stimulus in the local environment, by expanding in thickness resulting in a shift in resonance wavelength and thus an obvious change in color of the sensor, which color change is detectable by the naked-eye. Such layered geometries exhibit vibrant, macroscopic structural coloration owing to the broadband optical absorption of the top film, enabling the change in spacer thickness to be transduced visually, circumventing the need for sophisticated optical equipment for signal readout to observe the presence of the environmental stimulus. |
| FILED | Thursday, February 06, 2020 |
| APPL NO | 16/783712 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/29 (20130101) G01N 21/272 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11243188 | Pourmand et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Nader Pourmand (San Mateo, California); Boaz Vilozny (Santa Cruz, California); Paolo Actis (London, United Kingdom); R. Adam Seger (Santa Cruz, California) |
| ABSTRACT | Disclosed are methods and devices for detection of ion migration and binding, utilizing a nanopipette adapted for use in an electrochemical sensing circuit. The nanopipette may be functionalized on its interior bore with metal chelators for binding and sensing metal ions or other specific binding molecules such as boronic acid for binding and sensing glucose. Such a functionalized nanopipette is comprised in an electrical sensor that detects when the nanopipette selectively and reversibly binds ions or small molecules. Also disclosed is a nanoreactor, comprising a nanopipette, for controlling precipitation in aqueous solutions by voltage-directed ion migration, wherein ions may be directed out of the interior bore by a repulsing charge in the bore. |
| FILED | Friday, May 24, 2019 |
| APPL NO | 16/422735 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/021 (20130101) B01L 3/50273 (20130101) B01L 2300/0896 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 35/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3277 (20130101) G01N 27/44791 (20130101) Original (OR) Class G01N 33/48721 (20130101) Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 60/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11243295 | Spuler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University Corporation for Atmospheric Research (Boulder, Colorado); Montana State University (Bozeman, Montana); NASA Langley Research Center (Hampton, Virginia) |
| ASSIGNEE(S) | University Corporation for Atmospheric Research (Boulder, Colorado); Montana State University (Bozeman, Montana); NASA Langley Research Center (Hampton, Virginia) |
| INVENTOR(S) | Scott M. Spuler (Westminster, Colorado); Kevin S. Repasky (Bozeman, Montana); Amin R. Nehrir (Yorktown, Virginia) |
| ABSTRACT | A filter for a micropulse differential absorption LIDAR is provided. The filter comprises an etalon including a free spectral range substantially the same as a difference between a first laser wavelength and a second laser wavelength, the etalon further including a finesse providing substantial background noise suppression and substantially constant transmission of the first laser wavelength and the second laser wavelength over a predetermined range of wavelengths, and a first filter having a first filter bandpass selected to include the first laser wavelength and the second laser wavelength. |
| FILED | Thursday, June 28, 2018 |
| APPL NO | 16/022320 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/538 (20130101) G01N 2021/1795 (20130101) G01N 2021/4709 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/484 (20130101) G01S 7/4812 (20130101) G01S 7/4814 (20130101) Original (OR) Class G01S 7/4816 (20130101) G01S 17/18 (20200101) G01S 17/95 (20130101) Technologies for Adaptation to Climate Change Y02A 90/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11243561 | Mautner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE CHARLES STARK DRAPER LABORATORY, INC. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | THE CHARLES STARK DRAPER LABORATORY, INC. (Cambridge, Massachusetts) |
| INVENTOR(S) | Eric Karl Mautner (Hudson, Massachusetts); Brianna Klingensmith (Arlington, Massachusetts) |
| ABSTRACT | The present disclosure relates to systems and methods to maintain clock synchronization of multiple computers, or computer systems, through the exchange of communication messages that include clock and/or timing information. |
| FILED | Thursday, July 25, 2019 |
| APPL NO | 16/522163 |
| ART UNIT | 2187 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 1/12 (20130101) G06F 1/14 (20130101) Original (OR) Class G06F 13/122 (20130101) Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses H03L 7/0814 (20130101) H03L 7/0991 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 7/0025 (20130101) H04L 7/0037 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11244775 | Han et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Universities Space Research Association (Columbia, Maryland) |
| ASSIGNEE(S) | UNIVERSITIES SPACE RESEARCH ASSOCIATION (Columbia, Maryland) |
| INVENTOR(S) | Jin-Woo Han (Mountain View, California); Meyya Meyyappan (San Jose, California); Dong-Il Moon (Mountain View, California) |
| ABSTRACT | An all-printed physically unclonable function based on a single-walled carbon nanotube network. The network may be a mixture of semiconducting and metallic nanotubes randomly tangled with each other through the printing process. The unique distribution of carbon nanotubes in a network can be used for authentication, and this feature can be a secret key for a high level hardware security. The carbon nanotube network does not require any advanced purification process, alignment of nanotubes, high-resolution lithography and patterning. Rather, the intrinsic randomness of carbon nanotubes is leveraged to provide the unclonable aspect. |
| FILED | Wednesday, December 11, 2019 |
| APPL NO | 16/710760 |
| ART UNIT | 2833 — Electrical Circuits and Systems |
| CURRENT CPC | Resistors H01C 1/14 (20130101) H01C 1/034 (20130101) H01C 7/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11241671 | Petruska et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Melissa A. Petruska (Newtown, Connecticut); Trevor E. James (Plantsville, Connecticut); James D. Carruthers (Reno, Nevada); Peter C. Van Buskirk (Newtown, Connecticut); Jeffrey F. Roeder (Brookfield, Connecticut) |
| ASSIGNEE(S) | Sonata Scientific LLC (Danbury, Connecticut) |
| INVENTOR(S) | Melissa A. Petruska (Newtown, Connecticut); Trevor E. James (Plantsville, Connecticut); James D. Carruthers (Reno, Nevada); Peter C. Van Buskirk (Newtown, Connecticut); Jeffrey F. Roeder (Brookfield, Connecticut) |
| ABSTRACT | Monolithic composite photocatalysts for fluid purification, chemical transformations, and surface sterilization are disclosed. The monolithic composite photocatalysts comprise a photoactive nanocrystal component and a non-photoactive porous support. Photocatalytic fluid purification systems that contact an impurity-containing fluid with the subject monolithic composite photocatalysts are also disclosed. |
| FILED | Tuesday, November 12, 2019 |
| APPL NO | 16/680495 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/10 (20130101) A61L 2/16 (20130101) A61L 2/084 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/063 (20130101) Original (OR) Class B01J 35/004 (20130101) B01J 35/04 (20130101) B01J 35/006 (20130101) B01J 35/08 (20130101) B01J 35/023 (20130101) B01J 35/1014 (20130101) B01J 35/1019 (20130101) B01J 35/1023 (20130101) B01J 35/1061 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 35/00 (20130101) B82Y 40/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11243976 | Beckham et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tammy Beckham (Manhattan, Kansas); Matthew Coats (Washington, District of Columbia); John Korslund (Riverdale, Maryland); Michelle Colby (Washington, District of Columbia); James Wall (College Station, Texas); Keith Biggers (College Station, Texas); Melissa Berquist (College Station, Texas); Austin Riddle (College Station, Texas); Paul Bilnoski (College Station, Texas); Derek Overby (Covington, Louisiana); Graham Booker (College Station, Texas); Lindsey Holmstrom (Manhattan, Kansas) |
| ABSTRACT | A system and computerized method for monitoring and analyzing animal related data. In one embodiment, the system includes a processor and memory operable to identify a parameter related to animal management for species in a biological environment, aggregate animal related data from different sources about the parameter of the species, identify a baseline for the parameter, correlate the animal related data against the baseline to obtain correlated data, and analyze said correlated data to assess said animal management. |
| FILED | Friday, March 23, 2018 |
| APPL NO | 15/933910 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 11/008 (20130101) A01K 29/005 (20130101) Electric Digital Data Processing G06F 3/04847 (20130101) G06F 16/26 (20190101) Original (OR) Class G06F 16/29 (20190101) G06F 40/106 (20200101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/10 (20130101) G06Q 50/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 11243976 | Beckham et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tammy Beckham (Manhattan, Kansas); Matthew Coats (Washington, District of Columbia); John Korslund (Riverdale, Maryland); Michelle Colby (Washington, District of Columbia); James Wall (College Station, Texas); Keith Biggers (College Station, Texas); Melissa Berquist (College Station, Texas); Austin Riddle (College Station, Texas); Paul Bilnoski (College Station, Texas); Derek Overby (Covington, Louisiana); Graham Booker (College Station, Texas); Lindsey Holmstrom (Manhattan, Kansas) |
| ABSTRACT | A system and computerized method for monitoring and analyzing animal related data. In one embodiment, the system includes a processor and memory operable to identify a parameter related to animal management for species in a biological environment, aggregate animal related data from different sources about the parameter of the species, identify a baseline for the parameter, correlate the animal related data against the baseline to obtain correlated data, and analyze said correlated data to assess said animal management. |
| FILED | Friday, March 23, 2018 |
| APPL NO | 15/933910 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 11/008 (20130101) A01K 29/005 (20130101) Electric Digital Data Processing G06F 3/04847 (20130101) G06F 16/26 (20190101) Original (OR) Class G06F 16/29 (20190101) G06F 40/106 (20200101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/10 (20130101) G06Q 50/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11244527 | Hastings et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | William Hastings (Alexandria, Virginia); Sherif Ahmed (Starnberg, Germany); James Gilkeson (Alexandria, Virginia); Douglas MacIvor (Arlington, Virginia); Luke Olsen (Alexandria, Virginia) |
| ABSTRACT | Various embodiments of the present invention are directed toward systems and methods relating to security screening. For example, a screening system includes a chamber configured to accommodate a user to be screened, and a chamber scanner. The chamber scanner is configured to scan the user to identify whether the user is carrying an undivested item that needs to be divested. The chamber is configured to release the user to proceed from the chamber to a secure area, upon confirmation that no undivested items are to be divested. |
| FILED | Friday, April 03, 2020 |
| APPL NO | 16/839763 |
| ART UNIT | 2631 — Digital Communications |
| CURRENT CPC | Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 5/0041 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/265 (20130101) Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere G07C 9/28 (20200101) Original (OR) Class Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/182 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 11241189 | Smiley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia); The MetroHealth System (Cleveland, Ohio) |
| ASSIGNEE(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio); THE METROHEALTH SYSTEM (Cleveland, Ohio); THE U.S. GOV'T AS REPRESENTED BY THE DEPT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Aref Smiley (Cleveland, Ohio); Dennis Bourbeau (Cleveland Hts., Ohio); Margot S. Damaser (Cleveland Hts., Ohio); Steve Majerus (University Hts., Ohio); Massarat Zutshi (Cleveland Hts., Ohio); Ian Mcadams (Cleveland Hts., Ohio) |
| ABSTRACT | A sensing device can be placed within the colon to study bowel function. The sensing device can include a flexible printed circuit board that includes at least one senor configured to record data related to bowel activity from a patient's colon; and a wireless transmitter configured to send the data from the patient's colon to an external device. The sensing device can also include at least one mucosal clip configured to fix the sensor board to a wall of the patient's colon for a measurement period. The flexible printed circuit board and/or the at least one mucosal clip are configured to be passed from the patient's colon after the measurement period through normal defecation. |
| FILED | Wednesday, July 17, 2019 |
| APPL NO | 16/514982 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/07 (20130101) A61B 5/0022 (20130101) A61B 5/0031 (20130101) A61B 5/4255 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11242339 | Mallampalli et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Rama K. Mallampalli (Sewickley, Pennsylvania); Beibei Chen (Sewickley, Pennsylvania); Charleen T. Chu (Wexford, Pennsylvania); Yuan Liu (Sewickley, Pennsylvania) |
| ABSTRACT | A method for treating a neurodegenerative disease or an inflammatory disorder in a subject, comprising administering to the subject in need thereof, a compound, or a pharmaceutically acceptable salt thereof, of formula II: wherein each of R3-R7 is independently H, halogen, optionally-substituted alkyl, amino, alkoxy or hydroxy; R8 is an optionally-substituted heterocycloalkyl; and a is 0 to 3. |
| FILED | Monday, June 25, 2018 |
| APPL NO | 16/624843 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/517 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/16 (20180101) A61P 25/28 (20180101) Heterocyclic Compounds C07D 405/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 11241189 | Smiley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia); The MetroHealth System (Cleveland, Ohio) |
| ASSIGNEE(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio); THE METROHEALTH SYSTEM (Cleveland, Ohio); THE U.S. GOV'T AS REPRESENTED BY THE DEPT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Aref Smiley (Cleveland, Ohio); Dennis Bourbeau (Cleveland Hts., Ohio); Margot S. Damaser (Cleveland Hts., Ohio); Steve Majerus (University Hts., Ohio); Massarat Zutshi (Cleveland Hts., Ohio); Ian Mcadams (Cleveland Hts., Ohio) |
| ABSTRACT | A sensing device can be placed within the colon to study bowel function. The sensing device can include a flexible printed circuit board that includes at least one senor configured to record data related to bowel activity from a patient's colon; and a wireless transmitter configured to send the data from the patient's colon to an external device. The sensing device can also include at least one mucosal clip configured to fix the sensor board to a wall of the patient's colon for a measurement period. The flexible printed circuit board and/or the at least one mucosal clip are configured to be passed from the patient's colon after the measurement period through normal defecation. |
| FILED | Wednesday, July 17, 2019 |
| APPL NO | 16/514982 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/07 (20130101) A61B 5/0022 (20130101) A61B 5/0031 (20130101) A61B 5/4255 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 11244274 | Klausner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Peter Klausner (Washington, District of Columbia); Robert E. Dixon, Jr. (Haymarket, Virginia) |
| ABSTRACT | Systems described herein for controlling, requesting, and coordinating the creation and generation of labels can be a label broker, providing a centralized location for storing label information created by various entities, and managing the requests for generation of physical labels coming from various sources and entities. |
| FILED | Monday, April 30, 2018 |
| APPL NO | 15/967141 |
| ART UNIT | 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/083 (20130101) Original (OR) Class G06Q 50/28 (20130101) Ticket-issuing Apparatus; Fare-registering Apparatus; Franking Apparatus G07B 17/00016 (20130101) G07B 17/00314 (20130101) G07B 17/00508 (20130101) G07B 2017/00064 (20130101) G07B 2017/00161 (20130101) G07B 2017/00258 (20130101) G07B 2017/00588 (20130101) Coin-freed or Like Apparatus G07F 17/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 11242761 | Behling et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Weston Behling (Norwalk, Connecticut); Michael C. Weber (Niantic, Connecticut); William B. McLean (East Hampton, Connecticut); William S. Pratt (West Hartford, Connecticut); Joon Ha (Glastonbury, Connecticut) |
| ABSTRACT | A rotor disk assembly for a gas turbine engine includes a rotor disk that defines an axis, the rotor disk comprising a slot within a rim of the disk and a spacer within the slot, the spacer having a clearance feature sized to permit rotation of a rotor blade from an insertion position to an installed position. |
| FILED | Tuesday, February 18, 2020 |
| APPL NO | 16/793307 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/32 (20130101) F01D 5/303 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
11243955 — Latent token representations for passage and answer scoring in question answering systems
| US 11243955 | Ackermann et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Christopher F. Ackermann (Fairfax, Virginia); Charles E. Beller (Baltimore, Maryland); Stephen A. Boxwell (Columbus, Ohio); Edward G. Katz (Washington, District of Columbia); Kristen M. Summers (Takoma Park, Maryland) |
| ABSTRACT | The present invention may receive the question, a plurality of the candidate answers, and a plurality of documents associated with the plurality of candidate answers in the natural language. Then the present invention may tokenize the question, the plurality of the candidate answers, and the plurality of the documents into a corresponding n-gram sequence. The present invention may map n-gram elements from the tokenized question to the n-gram elements of the plurality of the tokenized candidate answers and the plurality of the tokenized documents using the latent token representation technique. The present invention may score the plurality of tokenized candidate answers based on the latent token representation technique. Then, the present invention may determine the precise answer based on the plurality of scored candidate answers. |
| FILED | Wednesday, November 29, 2017 |
| APPL NO | 15/825824 |
| ART UNIT | 2162 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/93 (20190101) G06F 16/243 (20190101) G06F 16/3329 (20190101) G06F 16/24564 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, February 08, 2022.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2021/details-patents-20210427.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page