FedInvent™ Patents

Patent Details for Tuesday, February 08, 2022 

This page was updated on Thursday, February 10, 2022 at 11:05 PM GMT

Department of Health and Human Services (HHS) 

US 11240996 Chernoff et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Institute For Cancer Research (Philadelphia, Pennsylvania)
ASSIGNEE(S) Institute For Cancer Research (Philadelphia, Pennsylvania)
INVENTOR(S) Jonathan Chernoff (Philadelphia, Pennsylvania);  Hoi Yee Chow (Philadelphia, Pennsylvania)
ABSTRACT Mice comprising a transgene encoding a peptide (iBox) inhibitor of Group B p21-activated kinase are provided. Also provided are cells, tissue, and organs obtained from such transgenic mice. Also provided are methods for producing mice comprising an iBox-encoding transgene.
FILED Wednesday, August 23, 2017
APPL NO 15/683948
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0275 (20130101) Original (OR) Class
A01K 67/0278 (20130101)
A01K 2217/052 (20130101)
A01K 2227/105 (20130101)
A01K 2267/0331 (20130101)

Peptides
C07K 14/4703 (20130101)
C07K 2319/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/14 (20130101)
C12N 9/1088 (20130101)

Enzymes
C12Y 205/01018 (20130101)
C12Y 306/05002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241155 Chen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Zhongping Chen (Irvine, California);  Yan Li (Irvine, California)
ABSTRACT An OCT system with a swept light source centered around 1.7 μm for identifying atherosclerotic plaque and visualization of large lipid pool is provided. Advantages for using the 1.7 μm swept source laser include higher contrast between lipid and normal tissue and deeper penetration of the optical signals from the 1.7 μm swept source laser into the tissue. With deeper penetration into the tissue, more structural information from deep within the tissue is obtained. The present invention also features multimodality imaging systems that integrate additional imaging systems into the OCT system at 1.7 μm. As an example, an integrated 1.3 μm and 1.7 μm OCT system is provided which simultaneously generates OCT images using both the OCT systems which are used to characterize and differentiate the types of tissue.
FILED Wednesday, January 24, 2018
APPL NO 15/878762
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0035 (20130101) Original (OR) Class
A61B 5/0066 (20130101)
A61B 5/0071 (20130101)
A61B 5/0075 (20130101)
A61B 5/0095 (20130101)
A61B 5/02028 (20130101)
A61B 8/12 (20130101)
A61B 8/485 (20130101)
A61B 8/5261 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241163 Sutton et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois)
ASSIGNEE(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois)
INVENTOR(S) Bradley P. Sutton (Savoy, Illinois);  Alexander M. Cerjanic (Champaign, Illinois);  Luisa Ciobanu (Gif-sur-Yvette, France);  Denis LeBihan (Gif-sur-Yvette, France);  Jing-Rebecca Li (Palaiseau, France);  Gabrielle Fournet (Gif-sur-Yvette, France)
ABSTRACT Aspects of the subject disclosure may include, for example, obtaining first magnetic resonance imaging (MRI) data of a subject, wherein the first MRI data is obtained during a first scan of a subject, wherein the first scan has a first diffusion sampling time, and wherein the first diffusion sampling time is selected in order to facilitate use of the first MRI data to determine a first Intravoxel Incoherent Motion (IVIM) effective diffusion coefficient in a Stationary Random Flow (SRF) regime; obtaining second MRI data of the subject, wherein the second MRI data is obtained during a second scan of the subject, wherein the second scan has a second diffusion sampling time, wherein the second diffusion sampling time is longer than the first diffusion sampling time, and wherein the second diffusion sampling time is selected in order to facilitate use of the second MRI data to determine a second IVIM effective diffusion coefficient in a pseudodiffusion regime; determining a blood velocity value based upon the first MRI data; and determining a segment length value based upon the second MRI data. Additional embodiments are disclosed.
FILED Thursday, June 07, 2018
APPL NO 16/002958
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101) Original (OR) Class
A61B 5/0263 (20130101)
A61B 5/489 (20130101)
A61B 5/4088 (20130101)
A61B 2576/026 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/56341 (20130101)
G01R 33/56366 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101)
G06T 2207/10016 (20130101)
G06T 2207/10088 (20130101)
G06T 2207/20104 (20130101)
G06T 2207/30101 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241170 Kim et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland);  BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan);  Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) University of Maryland, College Park (College Park, Maryland);  Board of Trustees of Michigan State University (East Lansing, Michigan);  Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Chang-Sei Kim (North Potomac, Maryland);  Stephanie Lind-Ober Martin (College Park, Maryland);  Jin-Oh Hahn (Rockville, Maryland);  Ramakrishna Mukkamala (Okemos, Michigan);  Omer T. Inan (Marietta, Georgia)
ABSTRACT A method and apparatus for monitoring arterial properties, including systolic and diastolic pressure levels, of a subject is provided, in which a hardware processor receives and analyzes ballistocardiogram (BCG) data of the subject. A non-transient computer readable medium, accessible by the hardware processor, contains instructions that, when executed by the hardware processor, identify features of the BCG waveform and determine the arterial properties therefrom. For example, a diastolic pressure level may be determined from a time interval between the ‘I’ and ‘J’ peaks of the waveform and a systolic pressure level determined from the amplitude difference between the ‘J’ and ‘K’ peaks of the waveform in combination with the ‘I-J’ time interval or amplitude difference. A physical mechanism for the BCG data is disclosed that enables other arterial properties of the subject to be determined from the BCG data alone or from the BCG data in combination with other measurements.
FILED Friday, April 06, 2018
APPL NO 15/946889
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/1102 (20130101) Original (OR) Class
A61B 5/02108 (20130101)
A61B 5/02438 (20130101)
A61B 5/7253 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241189 Smiley et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
Non-Profit Organization (NPO)
The Cleveland Clinic Foundation
APPLICANT(S) THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio);  The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia);  The MetroHealth System (Cleveland, Ohio)
ASSIGNEE(S) THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio);  THE METROHEALTH SYSTEM (Cleveland, Ohio);  THE U.S. GOV'T AS REPRESENTED BY THE DEPT OF VETERANS AFFAIRS (Washington, District of Columbia)
INVENTOR(S) Aref Smiley (Cleveland, Ohio);  Dennis Bourbeau (Cleveland Hts., Ohio);  Margot S. Damaser (Cleveland Hts., Ohio);  Steve Majerus (University Hts., Ohio);  Massarat Zutshi (Cleveland Hts., Ohio);  Ian Mcadams (Cleveland Hts., Ohio)
ABSTRACT A sensing device can be placed within the colon to study bowel function. The sensing device can include a flexible printed circuit board that includes at least one senor configured to record data related to bowel activity from a patient's colon; and a wireless transmitter configured to send the data from the patient's colon to an external device. The sensing device can also include at least one mucosal clip configured to fix the sensor board to a wall of the patient's colon for a measurement period. The flexible printed circuit board and/or the at least one mucosal clip are configured to be passed from the patient's colon after the measurement period through normal defecation.
FILED Wednesday, July 17, 2019
APPL NO 16/514982
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/07 (20130101)
A61B 5/0022 (20130101)
A61B 5/0031 (20130101)
A61B 5/4255 (20130101) Original (OR) Class

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/36007 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241190 Viswanath et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S) Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S) Satish Viswanath (Beachwood, Ohio);  Iulia Barbur (Akron, Ohio)
ABSTRACT Embodiments discussed herein facilitate predicting response to therapy in Crohn's disease. A first set of embodiments discussed herein relates to accessing a radiological image of a region of tissue demonstrating Crohn's disease associated with a patient; defining a mesenteric fat region by segmenting mesenteric fat represented in the radiological image; extracting a set of radiomic features from the mesenteric fat region; providing the set of radiomic features to a machine learning classifier configured to compute a probability of response to therapy in Crohn's disease based, at least in part, on the set of radiomic features; receiving, from the machine learning classifier, a probability that the region of tissue will respond to therapy; generating a classification of the patient as a responder or non-responder based, at least in part, on the probability; and displaying the classification.
FILED Monday, September 16, 2019
APPL NO 16/571454
ART UNIT 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0037 (20130101)
A61B 5/4255 (20130101) Original (OR) Class

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/6231 (20130101)

Computer Systems Based on Specific Computational Models
G06N 7/046 (20130101)
G06N 20/00 (20190101)

Image Data Processing or Generation, in General
G06T 7/11 (20170101)
G06T 7/0012 (20130101)
G06T 2207/10088 (20130101)
G06T 2207/30028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241207 Wen
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The USA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Han Wen (Bethesda, Maryland)
ABSTRACT This disclosure generally relates to systems, methods, and devices for performing high-resolution computer tomography (CT) scans providing highly detailed images of particular regions using whole body clinical CT scanners while maintaining high imaging speeds and low dose levels. In particular, the disclosed systems use flat panel detectors in conjunction with common CT detectors to quickly produce high-resolution CT images.
FILED Tuesday, August 14, 2018
APPL NO 16/639469
ART UNIT 2884 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/032 (20130101)
A61B 6/482 (20130101) Original (OR) Class
A61B 6/547 (20130101)
A61B 6/585 (20130101)
A61B 6/4208 (20130101)
A61B 6/5258 (20130101)

Image Data Processing or Generation, in General
G06T 7/10 (20170101)
G06T 11/005 (20130101)
G06T 2207/10081 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241380 Freeman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) William Freeman (Del Mar, California);  Michael J. Sailor (La Jolla, California);  Lingyun Cheng (San Diego, California);  Frederique Cunin (Montpellier, France);  Emily Anglin (San Diego, California);  Yang Yang Li (Hong Kong, China Hong Kong)
ABSTRACT A minimally invasive controlled drug delivery system for delivering a particular drug or drugs to a particular location of the eye, the system including a porous film template having pores configured and dimensioned to at least partially receive at least one drug therein, and wherein the template is dimensioned to be delivered into or onto the eye.
FILED Monday, November 06, 2017
APPL NO 15/804856
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 9/0017 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0048 (20130101) Original (OR) Class
A61K 9/0051 (20130101)
A61K 9/1611 (20130101)
A61K 9/7007 (20130101)
A61K 31/573 (20130101)
A61K 47/24 (20130101)
A61K 47/26 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 27/02 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241394 Zhang et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Liangfang Zhang (San Diego, California);  Che-Ming Jack Hu (Novato, California);  Ronnie H. Fang (San Diego, California);  Brian T. Luk (San Diego, California);  Kuei-Chun Wang (San Diego, California);  Shu Chien (La Jolla, California)
ABSTRACT The present invention relates to prevention and/or treatment of diseases or disorders associated with a damaged or leaky vasculature in a subject. The present invention provides for methods, combinations and pharmaceutical compositions for preventing and/or treating a disease or disorder associated with a damaged or leaky vasculature in a subject, using, inter alia, an effective amount of a nanoparticle comprising an inner core comprising a non-cellular material, an outer surface comprising a cellular membrane derived from a platelet; and optionally an agent for preventing, treating, diagnosing, or prognosing the disease or disorder and/or monitoring prevention or treatment of the disease or disorder. Exemplary diseases or disorders include hemorrhage (bleeding), cardiovascular diseases or disorders, diseases or disorders associated with narrowing of a blood vessel, tumors or cancers.
FILED Tuesday, June 07, 2016
APPL NO 15/737566
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5153 (20130101)
A61K 9/5169 (20130101)
A61K 9/5176 (20130101) Original (OR) Class
A61K 31/337 (20130101)
A61K 47/6901 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 7/04 (20180101)
A61P 9/00 (20180101)
A61P 35/00 (20180101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)
B82Y 30/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241421 Bushweller et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia)
ASSIGNEE(S) UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia)
INVENTOR(S) John H. Bushweller (Crozet, Virginia);  Anuradha Illendula (Crozet, Virginia)
ABSTRACT This invention relates to methods and compositions for treatment of inv(16) leukemia and particularly to treatment of acute myeloid leukemia. Disclosed is a method of treating inv(16) leukemia comprising the step of administering to a subject in need thereof a therapeutically effective combination of a) a compound of the formula (1) and b) a chemotherapeutic agent selected from the group consisting of pirarubicin, aclarubicin, mitoxantrone, doxorubicin, daunorubicin, idarubicin, epirubicin, cytarabine, pharmaceutically acceptable salts and mixtures thereof. The therapeutically effective combination synergistically inhibits proliferation of inv(16) leukemia cells. This invention also relates to pharmaceutical compositions comprising a therapeutically effective combination of the compound of formula (1) and the chemotherapeutic agent and a pharmaceutically acceptable excipient.
FILED Thursday, July 27, 2017
APPL NO 16/318041
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/704 (20130101)
A61K 31/4439 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/02 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241434 Strittmatter
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Institute on Aging (NIA)
APPLICANT(S) Yale University (New Haven, Connecticut)
ASSIGNEE(S) Yale Uninversity (New Haven, Connecticut)
INVENTOR(S) Stephen M. Strittmatter (Guilford, Connecticut)
ABSTRACT The present invention provides compositions and methods for treating and preventing an Aβ-modulated disease and/or a Tauopathy. In certain embodiments, the invention provides an inhibitor of Fyn tyrosine kinase, and methods of using the same. In certain embodiments, the inhibitor of the invention inhibits Aβ oligomer induced signaling and reduces or halts the progression of Alzheimer's Disease.
FILED Monday, March 16, 2020
APPL NO 16/820060
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/517 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/28 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241435 Wein et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts);  The Broad Institute, Inc. (Cambridge, Massachusetts);  Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts);  The Broad Institute, Inc. (Cambridge, Massachusetts);  Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S) Marc Wein (Boston, Massachusetts);  Henry Kronenberg (Boston, Massachusetts);  Thomas Sundberg (Boston, Massachusetts);  Ramnik Xavier (Brookline, Massachusetts);  Nathanael S. Gray (Stanford, California);  Yanke Liang (Belmont, Massachusetts);  Hwan Geun Choi (Chestnut Hill, Massachusetts);  Alykhan Shamji (Somerville, Massachusetts)
ABSTRACT The present disclosure provides methods of treating and/or preventing osteoporosis using salt-inducible kinase (SIK) inhibitors. Also provided are methods of using SIK inhibitors for increasing the function of osteocytes, increasing the number of osteoblasts, increasing the activity of osteoblasts, inhibiting the resorption of a bone, decreasing the number of osteoclasts, inhibiting the activity of osteoclasts, increasing the mass of a bone, down-regulating the expression of the gene SOST, and/or inhibiting the activity of sclerostin. The SIK inhibitors may be combined with Src inhibitors or CSF I R inhibitors. Exemplary SIK inhibitors include the compounds of the formula: (I), (II), (III), (IV), (V) or (VI).
FILED Saturday, September 16, 2017
APPL NO 16/333546
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/519 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 19/10 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241436 He et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Northwestern University (Evanston, Illinois);  The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland);  University of Kansas (Lawrence, Kansas)
ASSIGNEE(S) Northwestern University (Evanston, Illinois);  The United States of Americans represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland);  University of Kansas (Lawrence, Kansas)
INVENTOR(S) Congcong He (Chicago, Illinois);  Sui Huang (Chicago, Illinois);  Chen Wang (Chicago, Illinois);  Altea Rocchi (Evanston, Illinois);  Juan Jose Marugan (Gaithersburg, Maryland);  Marc Ferrer (Potomac, Maryland);  Samarjit Patnaik (Gaithersburg, Maryland);  Yuchi Chen (Rockville, Maryland);  Kevin Frankowski (Pittsboro, North Carolina);  Frank J. Schoenen (Lawrence, Kansas)
ABSTRACT The invention provides a compound of formula (I): wherein R1, R2, R3, and R4 are as defined herein, ginsenoside Rg2 of structure (II): or a combination thereof, for use in treating or preventing a condition responsive to the induction of autophagy in a brain of a mammal in need thereof.
FILED Thursday, January 25, 2018
APPL NO 16/480885
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/519 (20130101) Original (OR) Class
A61K 31/704 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241454 Pelus et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Indiana University Research and Technology Corporation (Indianapolis, Indiana)
ASSIGNEE(S) Indiana University Research and Technology Corporation (Indianapolis, Indiana)
INVENTOR(S) Louis M. Pelus (Indianapolis, Indiana);  Jonathan Hoggatt (Somerville, Massachusetts);  Pratibha Singh (Indianapolis, Indiana)
ABSTRACT This disclosure is directed to the methods of enhancing hematopoietic stem cells (HSPC) and progenitor cell (HSPC) engraftment procedure. Treatment in vivo of a HSPC donor with compounds that reduce PGE2 biosynthesis or PGE2 receptor antagonists alone, or in combination with other hematopoietic mobilization agents such as AMD3100 and G-CSF, increases the circulation of available HSPCs. Compounds that reduce the cellular synthesis of PGE2 include non-steroidal anti-inflammatory compounds such as indomethacin. Treatment ex vivo of HSPC with an effective amount of PGE2 or at least one of its derivatives such as 16,16-dimethyl prostaglandin E2 (dmPGE2), promotes HSPC engraftment. Similar methods may also be used to increase viral-mediated gene transduction efficacy into HSPC.
FILED Thursday, May 11, 2017
APPL NO 15/592375
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/00 (20130101)
A61K 31/395 (20130101)
A61K 31/405 (20130101)
A61K 31/4035 (20130101)
A61K 31/4196 (20130101)
A61K 31/5415 (20130101)
A61K 35/14 (20130101) Original (OR) Class
A61K 35/28 (20130101)
A61K 35/50 (20130101)
A61K 35/51 (20130101)
A61K 38/193 (20130101)
A61K 2035/124 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/16 (20130101)
C12N 5/0647 (20130101)
C12N 9/0083 (20130101)
C12N 15/63 (20130101)
C12N 15/86 (20130101)
C12N 2501/02 (20130101)

Enzymes
C12Y 114/99001 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241466 Archibong et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Minority Health and Health Disparities (NIMHD)
APPLICANT(S) Meharry Medical College (Nashville, Tennessee)
ASSIGNEE(S)
INVENTOR(S) Anthony E. Archibong (Antioch, Tennessee);  G. William Bates (Brentwood, Tennessee);  Elochukwu J. Ezekakpu (Nashville, Tennessee);  Lorin W. Simon (Antioch, Tennessee);  James E. K. Hildreth (Nashville, Tennessee)
ABSTRACT Artificial cervical fluid is disclosed that contains a mucilaginous extract from the okra plant. The mucilaginous extract can be produced using a hot aqueous extractant or cold extraction process followed by separation of larger particles from the extract. The extract finds many uses, for example as a sperm storage medium, a sperm freezing medium, a sexual lubricant, an artificial insemination medium, and an in vitro fertilization medium.
FILED Wednesday, March 06, 2019
APPL NO 16/294839
ART UNIT 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 1/021 (20130101)
A01N 1/0221 (20130101)

Diagnosis; Surgery; Identification
A61B 17/43 (20130101)

Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 6/04 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/06 (20130101)
A61K 9/0034 (20130101)
A61K 36/185 (20130101) Original (OR) Class
A61K 2236/33 (20130101)
A61K 2236/39 (20130101)
A61K 2236/53 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 15/08 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/061 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241480 Newberry et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Rodney Newberry (St. Louis, Missouri);  Kathryn Knoop (St. Louis, Missouri);  Keely McDonald (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Rodney Newberry (St. Louis, Missouri);  Kathryn Knoop (St. Louis, Missouri);  Keely McDonald (St. Louis, Missouri)
ABSTRACT Among the various aspects of the present disclosure is the provision of compositions and methods for modulation of dietary and microbial exposure. The present disclosure provides for compositions and methods for treating, preventing, or reducing the likelihood of development of an allergic disorder, necrotizing enterocolitis, sepsis, or an inflammatory disease, disorder, or condition in a subject including administering an effective amount of a composition comprising an EGFR ligand.
FILED Friday, January 26, 2018
APPL NO 15/880658
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0095 (20130101)
A61K 31/728 (20130101)
A61K 38/1808 (20130101) Original (OR) Class
A61K 38/1841 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 37/08 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241487 Daniell et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania);  UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida)
ASSIGNEE(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania);  UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida)
INVENTOR(S) Henry Daniell (Media, Pennsylvania);  Qiuhong Li (Gainesville, Florida);  Mohan K. Raizada (Alachua, Florida)
ABSTRACT Emerging evidence indicates that diminished activity of the vasoprotective axis of the renin-angiotensin system, constituting angiotensin converting enzyme2 (ACE2) and its enzymatic product, angiotensin-(1-7) [Ang-(1-7)] contribute to pulmonary hypertension (PH). However, clinical success for long-term delivery of ACE2 or Ang-(1-7) would require stability and ease of administration to increase patient compliance. Chloroplast expression of therapeutic proteins enables their bioencapsulation within plant cells to protect from acids and gastric enzymes; fusion to a transmucosal carrier facilitates effective systemic absorption. Oral feeding of rats with bioencapsulated ACE2 or Ang-(1-7) attenuated monocrotaline (MCT)-induced increase in right ventricular systolic pressure, decreased pulmonary vessel wall thickness and improved right heart function in both prevention and reversal protocols. Furthermore, combination of ACE2 and Ang-(1-7) augmented the beneficial effects against cardio-pulmonary pathophysiology induced by MCT administration. Experiments have also been performed which indicate that this approach is also suitable for the treatment or inhibition of experimental uveitis and autoimmune uveoretinitis These studies provide proof-of-concept for a novel low-cost oral ACE2 or Ang-(1-7) delivery system using transplastomic technology for pulmonary and ocular disease therapeutics.
FILED Monday, August 24, 2020
APPL NO 17/001667
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/19 (20130101)
A61K 9/0053 (20130101)
A61K 9/1664 (20130101)
A61K 9/5063 (20130101)
A61K 36/23 (20130101)
A61K 36/28 (20130101)
A61K 36/31 (20130101)
A61K 38/22 (20130101)
A61K 38/164 (20130101)
A61K 38/4813 (20130101) Original (OR) Class
A61K 47/65 (20170801)
A61K 47/6415 (20170801)

Peptides
C07K 14/28 (20130101)
C07K 2319/55 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/485 (20130101)
C12N 15/8214 (20130101)
C12N 15/8257 (20130101)

Enzymes
C12Y 304/15001 (20130101)
C12Y 304/17023 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241490 Weissman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Drew Weissman (Wynnewood, Pennsylvania);  Norbert Pardi (Philadelphia, Pennsylvania);  Michael Hogan (Philadelphia, Pennsylvania)
ABSTRACT The present invention relates to compositions and methods for inducing an adaptive immune response against Zika virus (ZIKV) in a subject. In certain embodiments, the present invention provides a composition comprising a nucleoside-modified nucleic acid molecule encoding a ZIKV antigen, adjuvant, or a combination thereof. For example, in certain embodiments, the composition comprises a vaccine comprising a nucleoside-modified nucleic acid molecule encoding a ZIKV antigen, adjuvant, or a combination thereof.
FILED Thursday, January 11, 2018
APPL NO 16/477258
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5123 (20130101)
A61K 39/12 (20130101) Original (OR) Class
A61K 2039/53 (20130101)
A61K 2039/55 (20130101)
A61K 2039/545 (20130101)
A61K 2039/55511 (20130101)
A61K 2039/55555 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2770/24134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241491 Baric et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S) Ralph Baric (Haw River, North Carolina);  Matthew Begley (Durham, North Carolina);  Douglas Widman (Newton Center, Massachusetts);  Aravinda Desilva (Chapel Hill, North Carolina);  Usha Nivarthi (Morrisville, North Carolina);  Boyd Yount (Hillsborough, North Carolina);  Ellen Young (Hillsborough, North Carolina)
ABSTRACT The present invention provides compositions and methods of use comprising a chimeric dengue virus E glycoprotein comprising a dengue virus E glycoprotein backbone, which comprises amino acid substitutions that introduce a dengue virus E glycoprotein epitope from a dengue virus serotype that is different from the dengue virus serotype of the dengue virus E glycoprotein backbone.
FILED Wednesday, May 23, 2018
APPL NO 16/615350
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101) Original (OR) Class
A61K 2039/70 (20130101)
A61K 2039/575 (20130101)
A61K 2039/5254 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2770/24122 (20130101)
C12N 2770/24123 (20130101)
C12N 2770/24134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241492 Kawaoka et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Centers of Excellence for Influenza Research and Surveillance (CEIRS)
APPLICANT(S) Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin)
INVENTOR(S) Yoshihiro Kawaoka (Middleton, Wisconsin);  Yuri Furusawa (Tokyo, Japan)
ABSTRACT The disclosure provides for an isolated recombinant influenza virus having at least one of: a PB2 viral segment encoding PB2 with residue at position 540 that is not asparagine or a residue at position 712 that is not glutamic acid, a PA viral segment encoding PA with a residue at position 180 that is not glutamine or a residue at position 200 that is not threonine, or a PB1 viral segment encoding PB1 with a residue at position 149 that is not valine, a residue at position 684 that is not glutamic acid or a residue at position 685 that is not aspartic acid, or any combination thereof, and methods of making and using the virus.
FILED Wednesday, January 22, 2020
APPL NO 16/749910
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/145 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/16 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241504 Jayasuriya et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) The University of Toledo (Toledo, Ohio)
ASSIGNEE(S) The University of Toledo (Toledo, Ohio)
INVENTOR(S) Ambalangodage C. Jayasuriya (Toledo, Ohio);  Bipin Gaihre (Toledo, Ohio)
ABSTRACT Compositions for delivering one or more active substances, or for repairing a bone, and methods of making and using the same, are described.
FILED Tuesday, July 21, 2020
APPL NO 16/934474
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/1875 (20130101)
A61K 47/32 (20130101)
A61K 47/34 (20130101)
A61K 47/6903 (20170801) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241575 Bijanki et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
APPLICANT(S) Jon Timothy Willie (Atlanta, Georgia)
ASSIGNEE(S) Kelly C.R. Bijanki (Houston, Texas);  Jon T. Willie (St. Louis, Missouri)
INVENTOR(S) Kelly Cathryn Rowe Bijanki (Decatur, Georgia);  Cory Inman (Decatur, Georgia);  Nigel Pedersen (Decatur, Georgia);  Jon Timothy Willie (Atlanta, Georgia)
ABSTRACT A method of stimulating a patient's brain comprising delivering an electrical stimulation to at least one electrode causing stimulation of a person's anterior cingulum bundle, or especially causing stimulation of a person's dorsal portion of an anterior cingulum bundle resulting in emotional change(s) in a patient comprising one or more of the following: anxiolysis, mirth, analgesia, improved affective tone, enhanced cognitive focus, increased well-being, engagement, or optimism. Further embodiments contemplate an apparatus. Further embodiments contemplate two implanted electrodes within the dorsal portion of the anterior cingulum bundle spaced between about 5 mm and 8 mm apart, having electrical stimulation parameters of between about 1.0 mA and about 3.5 mA, between about 100 Hz to about 150 Hz, and having a pulse width of between about 100 microseconds to about 200 microseconds.
FILED Tuesday, September 04, 2018
APPL NO 16/121599
ART UNIT 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0531 (20130101) Original (OR) Class
A61N 1/36071 (20130101)
A61N 1/36096 (20130101)
A61N 1/36132 (20130101)
A61N 1/36135 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241576 Hansen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S) UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa)
ASSIGNEE(S) University of Iowa Research Foundation (Iowa City, Iowa)
INVENTOR(S) Marlan R. Hansen (Solon, Iowa);  Christopher Kaufmann (Coralville, Iowa)
ABSTRACT The present embodiment is an implantable device capable of controlling cochlear implant electrode insertion and positioning. The embodiment uses an implanted mechanical positioning unit to advance position and monitor an electrode array. The device can be controlled via an external controller to reposition or advance an electrode array at any point after implantation with no surgical re-intervention. A cochlear implant electrode array whose position can be advanced and modified over time to best fit a patient's evolving hearing pattern would improve functional outcomes and significantly expand the candidacy range for cochlear implantation to include patients with substantial residual hearing.
FILED Friday, June 24, 2016
APPL NO 15/759643
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/3468 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0541 (20130101) Original (OR) Class
A61N 1/36038 (20170801)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 41/09 (20130101)

Transmission
H04B 5/0037 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241579 Ardell et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Jeffrey L. Ardell (Oakland, California);  Kalyanam Shivkumar (Los Angeles, California)
ABSTRACT The present invention provides systems and methods for monitoring cardiac autonomic nervous system activity and modulating parasympathetic control of cardiac function.
FILED Friday, April 21, 2017
APPL NO 16/094594
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0551 (20130101)
A61N 1/36062 (20170801)
A61N 1/36114 (20130101) Original (OR) Class
A61N 1/36117 (20130101)
A61N 1/36139 (20130101)
A61N 1/36171 (20130101)
A61N 1/36507 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241586 Tsai et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Li-Huei Tsai (Cambridge, Massachusetts);  Anthony James Martorell (Cambridge, Massachusetts);  Ho-Jun Suk (Cambridge, Massachusetts);  Ed Boyden (Chestnut Hill, Massachusetts)
ABSTRACT Devices, systems, and methods for a treating dementia or Alzheimer's disease in a subject in need thereof. In one example, combined auditory and visual stimuli having a frequency of about 20 Hz to about 60 Hz, and more specifically about 40 Hz, are non-invasively delivered to the subject to induce synchronized gamma oscillations in at least one brain region of the subject. In particular, pursuant to various treatment and exposure protocols, combined auditory and visual stimulation (as opposed to auditory or visual stimulation alone) promotes a microglia response in the medial prefrontal cortex (mPFC). More generally, combined auditory and visual stimulation induces an extended microglia clustering response in the auditory cortex, the visual cortex, and the mPFC.
FILED Wednesday, September 19, 2018
APPL NO 16/135938
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 2021/0022 (20130101)
A61M 2021/0027 (20130101)
A61M 2210/0693 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/062 (20130101)
A61N 5/0618 (20130101) Original (OR) Class
A61N 5/0622 (20130101)
A61N 2005/063 (20130101)
A61N 2005/0626 (20130101)
A61N 2005/0647 (20130101)
A61N 2005/0651 (20130101)
A61N 2005/0667 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241689 Furtaw et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) LI-COR, Inc. (Lincoln, Nebraska)
ASSIGNEE(S) LI-COR, Inc. (Lincoln, Nebraska)
INVENTOR(S) Michael D. Furtaw (Lincoln, Nebraska);  Donald T. Lamb (Lincoln, Nebraska)
ABSTRACT Devices and methods are provided for the separation and dispensing of material using a microfluidic electrophoresis column, sheath liquid pump, and exit channel, all on the same monolithic chip. Material is separated in the electrophoresis column and passed into the exit chamber in response to a voltage potential between a first electrode within the electrophoresis column and a terminating electrode integrated into the chip. The terminating electrode can be in the sheath liquid pump chamber, the sheath liquid reservoir, or a separate flow channel that intersects the exit channel along with the electrophoresis column and sheath liquid pump chamber. The flow of sheath liquid into the exit chamber entrains separated analytes into an effluent that is dispensed out of the exit chamber via a discharge outlet.
FILED Monday, August 07, 2017
APPL NO 15/670896
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/50273 (20130101) Original (OR) Class
B01L 2300/0681 (20130101)
B01L 2300/0829 (20130101)
B01L 2400/0421 (20130101)
B01L 2400/0478 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/44721 (20130101)
G01N 27/44739 (20130101)
G01N 27/44773 (20130101)
G01N 27/44782 (20130101)
G01N 27/44791 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242296 Dussault et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) NUtech Ventures (Lincoln, Nebraska)
ASSIGNEE(S) NUtech Ventures (Lincoln, Nebraska)
INVENTOR(S) Patrick H. Dussault (Lincoln, Nebraska);  Andrew Olson (Lincoln, Nebraska)
ABSTRACT Disclosed herein is a method of reducing or disproportionating peroxide, comprising combining an organic chalcogenide, an iron salt, and the peroxide in the presence of an additional reductant, which can be the organic chalcogenide. The method can be used to, e.g., prepare alcohols from peroxides and to disproportionate hydrogen peroxide into water and oxygen.
FILED Wednesday, July 17, 2019
APPL NO 16/514423
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
General Methods of Organic Chemistry; Apparatus Therefor
C07B 41/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242314 Zhou et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Dong Zhou (St. Louis, Missouri);  Wenhua Chu (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Dong Zhou (St. Louis, Missouri);  Wenhua Chu (St. Louis, Missouri)
ABSTRACT The present disclosure relates to the methods for the preparation of reactive [F-18]fluoride in a form of [F-18]sulfonyl fluoride suitable for efficient radiolabeling without an azeotropic evaporation step by the use of anion exchange resin and sulfonyl chloride, and its applications in the manufacturing of PET radiopharmaceuticals.
FILED Wednesday, January 11, 2017
APPL NO 15/403954
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
General Methods of Organic Chemistry; Apparatus Therefor
C07B 59/001 (20130101)
C07B 59/002 (20130101)
C07B 59/005 (20130101)
C07B 2200/05 (20130101)

Acyclic or Carbocyclic Compounds
C07C 45/63 (20130101)
C07C 45/63 (20130101)
C07C 47/55 (20130101)
C07C 67/307 (20130101)
C07C 67/307 (20130101)
C07C 69/76 (20130101)
C07C 247/04 (20130101)
C07C 303/22 (20130101)
C07C 303/22 (20130101)
C07C 303/22 (20130101)
C07C 303/22 (20130101)
C07C 309/86 (20130101)
C07C 309/87 (20130101)
C07C 309/89 (20130101)
C07C 315/04 (20130101) Original (OR) Class

Heterocyclic Compounds
C07D 207/09 (20130101)
C07D 213/52 (20130101)
C07D 213/71 (20130101)
C07D 233/91 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 3/02 (20130101)
C07H 19/06 (20130101)

Steroids
C07J 1/007 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242317 Messick et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Wistar Institute of Anatomy and Biology (Philadelphia, Pennsylvania)
INVENTOR(S) Troy E. Messick (Upper Darby, Pennsylvania);  Garry R. Smith (Royersford, Pennsylvania);  Allen B. Reitz (Lansdale, Pennsylvania);  Paul M. Lieberman (Wynnewood, Pennsylvania);  Mark E. McDonnell (Lansdale, Pennsylvania);  Yan Zhang (Fort Washington, Pennsylvania);  Venkata Velvadapu (Ankeny, Iowa)
ABSTRACT Pharmaceutical compositions of the invention comprise EBNA1 inhibitors useful for the treatment of diseases caused by EBNA1 activity such as cancer, infectious mononucleosis, chronic fatigue syndrome, multiple sclerosis, systemic lupus erythematosus and rheumatoid arthritis. Pharmaceutical compositions of the invention also comprise EBNA1 inhibitors useful for the treatment of diseases caused by latent Epstein-Barr Virus (EBV) infection. Pharmaceutical compositions of the invention also comprise EBNA1 inhibitors useful for the treatment of diseases caused by lytic Epstein-Barr Virus (EBV) infection.
FILED Tuesday, July 23, 2019
APPL NO 16/519590
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/44 (20130101)
A61K 31/192 (20130101)
A61K 31/404 (20130101)
A61K 31/496 (20130101)
A61K 31/4439 (20130101)

Acyclic or Carbocyclic Compounds
C07C 53/18 (20130101)
C07C 63/66 (20130101)
C07C 65/19 (20130101)
C07C 65/28 (20130101)
C07C 211/27 (20130101)
C07C 217/84 (20130101)
C07C 229/56 (20130101)
C07C 229/64 (20130101)
C07C 233/11 (20130101)
C07C 233/64 (20130101)
C07C 233/65 (20130101)
C07C 235/58 (20130101)
C07C 255/54 (20130101)
C07C 255/55 (20130101)
C07C 311/08 (20130101)
C07C 311/16 (20130101)
C07C 311/17 (20130101)
C07C 317/14 (20130101)
C07C 317/44 (20130101)
C07C 2601/02 (20170501)

Heterocyclic Compounds
C07D 207/08 (20130101)
C07D 207/12 (20130101)
C07D 207/14 (20130101)
C07D 207/16 (20130101)
C07D 207/327 (20130101) Original (OR) Class
C07D 209/08 (20130101)
C07D 211/70 (20130101)
C07D 213/55 (20130101)
C07D 213/64 (20130101)
C07D 213/74 (20130101)
C07D 215/14 (20130101)
C07D 231/12 (20130101)
C07D 235/06 (20130101)
C07D 239/26 (20130101)
C07D 249/06 (20130101)
C07D 277/30 (20130101)
C07D 295/155 (20130101)
C07D 307/79 (20130101)
C07D 333/54 (20130101)
C07D 401/04 (20130101)
C07D 401/10 (20130101)
C07D 403/10 (20130101)
C07D 409/10 (20130101)
C07D 417/10 (20130101)
C07D 471/04 (20130101)
C07D 487/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242326 Bai et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Yugang Bai (Changsha, China PRC);  Steven C. Zimmerman (Champaign, Illinois);  Auinash Kalsotra (Champaign, Illinois)
ABSTRACT Abnormally long r(CUG)n repeat expansion is believed to be the major cause of Myotonic dystrophy type 1 (DM1) because it binds to muscleblind-like 1 (MBNL 1) protein which regulates RNA splicing, leading to the mis-splicing of more than 100 pre-mRNAs. The rational design of oligomers with alternating bisamidine and melamine structure resulted in good binding affinity to the RNA target because of a multivalent effect. The oligomers also showed excellent activity in disrupting nuclear foci, reversing the mis-splicing of IR minigene, and sabotaging the toxic RNA biosynthesis. Excellent activity in Drosophila based DM1 models was also observed for the oligomers, rescuing the climbing ability of the flies upon oral treatment.
FILED Thursday, August 23, 2018
APPL NO 16/641450
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/06 (20130101)
A61K 9/0019 (20130101)
A61K 9/2054 (20130101)
A61K 9/2059 (20130101)
A61K 9/4858 (20130101)

Heterocyclic Compounds
C07D 251/64 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242338 Messick et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) THE WISTAR INSTITUTE (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Wistar Institute (Philadelphia, Pennsylvania)
INVENTOR(S) Troy E. Messick (Upper Darby, Pennsylvania);  Paul M. Lieberman (Wynnewood, Pennsylvania);  Garry R. Smith (Elverson, Pennsylvania);  Arlindo L. Castelhano (New York, New York)
ABSTRACT The invention relates, in certain aspects, to developable forms of certain compounds that are useful to treat and/or prevent EBV infection and related conditions in a subject. The invention further provides EBNA1 inhibitors, and/or pharmaceutical compositions comprising the same, that are useful for the treatment of diseases caused by latent Epstein-Barr Virus (EBV) infection and/or lytic EBV infection.
FILED Thursday, May 16, 2019
APPL NO 16/414198
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0053 (20130101)
A61K 31/404 (20130101)
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/28 (20180101)
A61P 31/22 (20180101)
A61P 35/02 (20180101)

General Methods of Organic Chemistry; Apparatus Therefor
C07B 2200/13 (20130101)

Heterocyclic Compounds
C07D 405/12 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242339 Mallampalli et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Office of Research and Development (DVAORD)
Veterans Health Administration (VHA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute on Aging (NIA)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Rama K. Mallampalli (Sewickley, Pennsylvania);  Beibei Chen (Sewickley, Pennsylvania);  Charleen T. Chu (Wexford, Pennsylvania);  Yuan Liu (Sewickley, Pennsylvania)
ABSTRACT A method for treating a neurodegenerative disease or an inflammatory disorder in a subject, comprising administering to the subject in need thereof, a compound, or a pharmaceutically acceptable salt thereof, of formula II:
wherein each of R3-R7 is independently H, halogen, optionally-substituted alkyl, amino, alkoxy or hydroxy; R8 is an optionally-substituted heterocycloalkyl; and a is 0 to 3.
FILED Monday, June 25, 2018
APPL NO 16/624843
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/517 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/16 (20180101)
A61P 25/28 (20180101)

Heterocyclic Compounds
C07D 405/12 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242368 Harris
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
INVENTOR(S) Samantha P. Harris (Tucson, Arizona)
ABSTRACT Methods and compositions for rapidly replacing cMyBP-C in sarcomeres featuring the creation of Spy-C mice, which are mice genetically engineered to express cMyBP-C with a protease recognition site and SpyTag peptide introduced into the cMyBP-C gene. In permeabilized myocytes from the Spy-C mice, the cMyBP-C protein can be cleaved at the protease recognition site, and the N-Terminus of cMyBP-C can be removed while the C-terminus remains anchored to the thick filament. A new peptide featuring the SpyCatcher sequence can be covalently bonded to the remaining portion of cMyBP-C, thereby creating a modified cMyBP-C protein. The methods and compositions of the present invention allow for the reconstitution of full-length cMyBP-C at the precise position of native cMyBP-C in the sarcomere and allow for a variety of modifications to be introduced to cMyBP-C in situ.
FILED Monday, September 23, 2019
APPL NO 16/579445
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 14/47 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/907 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242378 Bornholdt et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) MAPP BIOPHARMACEUTICAL, INC. (San Diego, California);  Albert Einstein College of Medicine (Bronx, New York);  Adimab, LLC (Lebanon, New Hampshire)
ASSIGNEE(S) MAPP BIOPHARMACEUTICAL, INC. (San Diego, California);  ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York);  ADIMAB, LLC (Lebanon, New Hampshire)
INVENTOR(S) Zachary A. Bornholdt (Encinitas, California);  Larry Zeitlin (San Diego, California);  Kartik Chandran (Brooklyn, New York);  Anna Wec (Lebanon, New Hampshire);  Laura Walker (Norwich, Vermont)
ABSTRACT Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially, similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.
FILED Tuesday, June 09, 2020
APPL NO 16/896980
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/42 (20130101)
A61K 2039/55 (20130101)
A61K 2039/57 (20130101)
A61K 2039/62 (20130101)
A61K 2039/505 (20130101)
A61K 2039/545 (20130101)
A61K 2039/6075 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)

Peptides
C07K 16/10 (20130101) Original (OR) Class
C07K 2317/76 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242379 Bornholdt et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) MAPP BIOPHARMACEUTICAL, INC. (San Diego, California);  Albert Einstein College of Medicine (Bronx, New York);  Adimab, LLC (Lebanon, New Hampshire)
ASSIGNEE(S) MAPP BIOPHARMACEUTICAL, INC. (San Diego, California);  ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York);  ADIMAB, LLC (Lebanon, New Hampshire)
INVENTOR(S) Zachary A. Bornholdt (Encinitas, California);  Larry Zeitlin (San Deigo, California);  Kartik Chandran (Brooklyn, New York);  Anna Wec (Lebanon, New Hampshire);  Laura Walker (Norwich, Vermont)
ABSTRACT Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.
FILED Tuesday, June 09, 2020
APPL NO 16/896991
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/42 (20130101)
A61K 2039/55 (20130101)
A61K 2039/57 (20130101)
A61K 2039/62 (20130101)
A61K 2039/505 (20130101)
A61K 2039/545 (20130101)
A61K 2039/6075 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)

Peptides
C07K 16/10 (20130101) Original (OR) Class
C07K 2317/76 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242509 Deng et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York)
ASSIGNEE(S) MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York)
INVENTOR(S) Liang Deng (New York, New York);  Stewart Shuman (New York, New York);  Ning Yang (New York, New York);  Taha Merghoub (New York, New York);  Jedd Wolchok (New York, New York)
ABSTRACT Disclosed herein are methods and compositions related to the treatment, prevention, and/or amelioration of cancer in a subject in need thereof. In particular aspects, the present technology relates to the use of poxviruses, including a recombinant modified vaccinia Ankara (MVA) virus or vaccinia virus with deletion of vaccinia host-range factor C7 (MVAΔC7L and VACVΔC7L, respectively), alone or in combination with immune checkpoint blocking agents, as an oncolytic and immunotherapeutic composition. In some embodiments, the technology of the present disclosure relates to a MVAΔC7L or VACVΔC7L virus further modified to express human Fms-like tyrosine kinase 3 ligand (Flt3L).
FILED Friday, May 11, 2018
APPL NO 16/612127
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/285 (20130101)
A61K 2039/54 (20130101)
A61K 2039/525 (20130101)
A61K 2039/55588 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101) Original (OR) Class
C12N 15/86 (20130101)
C12N 2710/24121 (20130101)
C12N 2710/24131 (20130101)
C12N 2710/24143 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242532 Guo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Ohio State Innovation Foundation (Columbus, Ohio);  Ball State University (Muncie, Indiana)
ASSIGNEE(S) Ohio State Innovation Foundation (Columbus, Ohio);  Ball State University (Muncie, Indiana)
INVENTOR(S) Peixuan Guo (Dublin, Ohio);  Daniel Jasinski (Columbus, Ohio);  Hui Li (San Francisco, California);  Emil Khisamutdinov (Muncie, Indiana)
ABSTRACT Disclosed herein are three-dimensional cage molecules, wherein the cage molecule is composed of RNA. Also disclosed is a composition including the three-dimensional cage molecule, as well as a pharmaceutical composition containing the three-dimensional cage molecule. Also disclosed herein are methods of administering a cage molecule, composition, or formulation thereof to a subject in need thereof.
FILED Wednesday, May 10, 2017
APPL NO 16/091747
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 48/005 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 37/04 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/10 (20130101)
C12N 15/11 (20130101)
C12N 15/113 (20130101)
C12N 15/115 (20130101) Original (OR) Class
C12N 15/117 (20130101)
C12N 2310/16 (20130101)
C12N 2310/17 (20130101)
C12N 2310/341 (20130101)
C12N 2320/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242561 Ju et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Jingyue Ju (Englewood Cliffs, New Jersey);  Dae Hyun Kim (Northbrook, Illinois);  Jia Guo (Chandler, Arizona);  Qinglin Meng (Foster City, California);  Zengmin Li (Flushing, New York);  Huanyan Cao (Zhangzhou, China PRC)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Jingyue Ju (Englewood Cliffs, New Jersey);  Dae Hyun Kim (Northbrook, Illinois);  Jia Guo (Chandler, Arizona);  Qinglin Meng (Foster City, California);  Zengmin Li (Flushing, New York);  Huanyan Cao (Zhangzhou, China PRC)
ABSTRACT This invention provides a process for sequencing nucleic acids using 3′ modified deoxynucleotide analogues or 3′ modified deoxyinosine triphosphate analogues, and 3′ modified dideoxynucleotide analogues having a detectable marker attached thereto.
FILED Monday, April 15, 2019
APPL NO 16/384461
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/70 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 19/04 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6869 (20130101)
C12Q 1/6874 (20130101) Original (OR) Class
C12Q 1/6876 (20130101)
C12Q 2523/107 (20130101)
C12Q 2523/319 (20130101)
C12Q 2535/101 (20130101)
C12Q 2535/113 (20130101)
C12Q 2563/107 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242562 Salk et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute on Aging (NIA)
APPLICANT(S) UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington)
ASSIGNEE(S) UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington)
INVENTOR(S) Jesse Salk (Seattle, Washington);  Lawrence A. Loeb (Bellevue, Washington);  Michael Schmitt (Seattle, Washington)
ABSTRACT Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand. This method uniquely capitalizes on the redundant information stored in double-stranded DNA, thus overcoming technical limitations of prior methods utilizing data from only one of the two strands.
FILED Thursday, August 30, 2018
APPL NO 16/118305
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101)
C12Q 1/6806 (20130101)
C12Q 1/6869 (20130101)
C12Q 1/6869 (20130101)
C12Q 1/6876 (20130101) Original (OR) Class
C12Q 2525/179 (20130101)
C12Q 2525/185 (20130101)
C12Q 2525/191 (20130101)
C12Q 2525/191 (20130101)
C12Q 2535/119 (20130101)
C12Q 2535/119 (20130101)
C12Q 2535/122 (20130101)
C12Q 2563/179 (20130101)
C12Q 2565/514 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242572 Wang et al.
FUNDED BY
Department of Defense (DOD)
Uniformed Services University of the Health Sciences (USUHS)
Henry M Jackson Foundation for the Advancement of Military Medicine, Inc (HJF)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland)
ASSIGNEE(S) THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (Bethesda, Maryland)
INVENTOR(S) Linfa Wang (Wandana Heights, Australia);  Glenn A. Marsh (Leopold, Australia);  Hume Field (Ormiston, Australia);  Christopher Broder (Silver Spring, Maryland)
ABSTRACT The present disclosure is directed towards a virus, called Cedar Virus, and its methods of use.
FILED Tuesday, March 12, 2019
APPL NO 16/351380
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/00 (20130101)
A61K 39/12 (20130101)
A61K 2039/543 (20130101)

Peptides
C07K 14/005 (20130101)
C07K 16/1027 (20130101)
C07K 2317/76 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2760/18221 (20130101)
C12N 2760/18222 (20130101)
C12N 2760/18231 (20130101)
C12N 2760/18234 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/70 (20130101)
C12Q 1/701 (20130101) Original (OR) Class
C12Q 2600/136 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11243188 Pourmand et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Human Genome Research Institute (NHGRI)
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Nader Pourmand (San Mateo, California);  Boaz Vilozny (Santa Cruz, California);  Paolo Actis (London, United Kingdom);  R. Adam Seger (Santa Cruz, California)
ABSTRACT Disclosed are methods and devices for detection of ion migration and binding, utilizing a nanopipette adapted for use in an electrochemical sensing circuit. The nanopipette may be functionalized on its interior bore with metal chelators for binding and sensing metal ions or other specific binding molecules such as boronic acid for binding and sensing glucose. Such a functionalized nanopipette is comprised in an electrical sensor that detects when the nanopipette selectively and reversibly binds ions or small molecules. Also disclosed is a nanoreactor, comprising a nanopipette, for controlling precipitation in aqueous solutions by voltage-directed ion migration, wherein ions may be directed out of the interior bore by a repulsing charge in the bore.
FILED Friday, May 24, 2019
APPL NO 16/422735
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/021 (20130101)
B01L 3/50273 (20130101)
B01L 2300/0896 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 35/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/3277 (20130101)
G01N 27/44791 (20130101) Original (OR) Class
G01N 33/48721 (20130101)

Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM]
G01Q 60/44 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11243208 Katchman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona);  THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona);  THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts)
INVENTOR(S) Benjamin Katchman (Tempe, Arizona);  Karen Anderson (Scottsdale, Arizona);  Garrick Wallstrom (Mesa, Arizona);  Joshua LaBaer (Chandler, Arizona);  Daniel Cramer (Chestnut Hill, Massachusetts)
ABSTRACT Compositions and methods relating to a panel of antigen biomarkers for the early detection of ovarian cancer. The compositions and methods encompass antigen biomarkers coupled to a substrate, with the biomarkers being selected from the group consisting of one or more of ICAM3, CTAG2, p53, STYXL1, PVR, POMC, NUDT11, TRIM39, UHMK1, KSR1, and NXF3.
FILED Tuesday, July 11, 2017
APPL NO 16/317184
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57449 (20130101) Original (OR) Class
G01N 2800/60 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11243213 Tarca et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) WAYNE STATE UNIVERSITY (Detroit, Michigan);  THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICE (Bethesda, Maryland)
ASSIGNEE(S) Wayne State University (Detroit, Michigan);  The United States of America as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Adi L. Tarca (South Lyon, Michigan);  Piya Chaemsaithong (Shatin, China Hong Kong);  Tinnakorn Chaiworapongsa (Grosse Pointe Park, Michigan);  Sonia S. Hassan (Novi, Michigan);  Roberto Romero (Grosse Pointe, Michigan)
ABSTRACT Biomarkers tests which can be used to predict a positive or negative risk of preeclampsia are described. More specifically, a panel of biomarkers including MMP-7 and gpIIbIIIa, described. The test is useful to predict preeclampsia when a biological sample is obtained between the 16th and 22nd week of pregnancy. Prediction later in pregnancy can be achieved by a combination of Siglec-6, Activin A, ALCAM, and/or FCN2.
FILED Monday, November 07, 2016
APPL NO 15/773978
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/16 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101)
C12Q 2600/158 (20130101)

Enzymes
C12Y 304/24007 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/689 (20130101) Original (OR) Class
G01N 2333/96494 (20130101)
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11243215 John et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Varghese John (Los Angeles, California);  Jesus Campagna (Playa Del Rey, California);  Tina Bilousova (Santa Monica, California);  Patricia R. Spilman (Mill Valley, California);  Peter James Heinzelman (Los Angeles, California);  Asa Hatami (Los Angeles, California);  Mohammad Parvez Alam (Los Angeles, California)
ABSTRACT In various embodiments methods are provided for identifying and/or quantifying one or more antigens of interest (biomarkers) on the surface of cell- or tissue-specific exosomes. In an illustrative embodiments the methods comprise: i) incubating a population of exosomes with one or more tissue-specific antibodies that bind an antigen specific to a tissue or cell type of interest that produces exosomes, where the tissue specific antibodies are attached to acceptor bead or magnetic beads so the antibodies bind exosomes displaying the antigen; ii) obtaining a purified population of exosomes bound by the tissue specific antibodies with and/or without photocleavable linker based technology; iii) incubating a test subset of the isolated tissue-specific exosomes with acceptor beads attached to test antibodies that bind an antigen of interest thereby binding exosomes that display the antigen of interest and a control subset with negative control acceptor beads; v) incubating the test subset of isolated exosomes and the control subset of exosomes with a donor-bearing antibody that binds an exosome specific antigen; and vi) detecting a signal produced upon illumination of the control subset and/or the test; and vii) detecting the antigen(s) of interest.
FILED Friday, January 13, 2017
APPL NO 16/070249
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Heterocyclic Compounds
C07D 207/46 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/542 (20130101)
G01N 33/567 (20130101)
G01N 33/6896 (20130101) Original (OR) Class
G01N 33/54313 (20130101)
G01N 33/54326 (20130101)
G01N 33/54353 (20130101)
G01N 33/57484 (20130101)
G01N 2570/00 (20130101)
G01N 2800/52 (20130101)
G01N 2800/285 (20130101)
G01N 2800/2821 (20130101)
G01N 2800/2835 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11243284 Overall et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) HeartVista, Inc. (Los Altos, California)
ASSIGNEE(S) HEARTVISTA, INC. (Los Altos, California)
INVENTOR(S) William Overall (Los Altos, California);  Juan Santos (Los Altos, California)
ABSTRACT A computer-implemented method for sequencing magnetic resonance imaging waveforms uses a multistage sequencing hardware. A method comprises creating, with the aid of a computer processor, an active memory region that includes waveforms and schedules being played, and creating one or more buffer memory regions that contain waveforms and schedules not currently being played. Next, the waveforms and schedules in the one or more buffer memory regions may be updated while waveforms may be played in the active memory region. Upon completion of the waveform playback in the active memory region, the active and buffer memory regions may be swapped so that the former buffer memory region becomes the active memory region, and the former active memory region becomes the buffer memory region. The method may be repeated as needed until the imaging process is completed or otherwise halted.
FILED Wednesday, January 08, 2020
APPL NO 16/737227
ART UNIT 2866 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/543 (20130101)
G01R 33/561 (20130101)
G01R 33/3852 (20130101)
G01R 33/4822 (20130101)
G01R 33/4824 (20130101)
G01R 33/5608 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11243391 Hillman
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Elizabeth M. C. Hillman (New York, New York)
ABSTRACT Implementing swept, confocally aligned planar excitation (SCAPE) imaging with asymmetric magnification in the detection arm provides a number of significant advantages. In some preferred embodiments, the asymmetric magnification is achieved using cylindrical lenses in the detection arm that are oriented to increase the magnification of the intermediate image in the width direction but not in the depth direction. SCAPE imaging may also be improved by using an SLM to modify a characteristic of the sheet of excitation light that is projected into the sample. Additional embodiments include a customized version of SCAPE that is optimized for imaging the retina at the back of an eyeball in living subjects.
FILED Tuesday, May 30, 2017
APPL NO 16/303017
ART UNIT 2872 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 3/14 (20130101)
A61B 3/1025 (20130101)

Optical Elements, Systems, or Apparatus
G02B 21/006 (20130101)
G02B 21/0032 (20130101)
G02B 21/0048 (20130101)
G02B 21/0052 (20130101)
G02B 21/0072 (20130101)
G02B 21/0076 (20130101)
G02B 21/367 (20130101) Original (OR) Class

Pictorial Communication, e.g Television
H04N 5/23296 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11244104 Jain et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Vignet Incorporated (Fairfax, Virginia)
ASSIGNEE(S) VigNet Incorporated (Fairfax, Virginia)
INVENTOR(S) Neeta Jain (Fairfax, Virginia);  Yue Cao (Vienna, Virginia);  Dave Klein (Oakton, Virginia);  Praduman Jain (Fairfax, Virginia)
ABSTRACT In some implementations, a system dynamically adjusts an electronic form of an application based on user data and form data specified for the electronic form. Form data that specifies characteristics of the electronic form is initially received by a computing device. The form data specifies one or more rules configured to vary the content of the electronic form that is presented for different users. User data indicating characteristics of a user is then obtained by the computing device. An interactive element is then selected from among a set of multiple interactive elements based on the received user data and the rules in the received form data. A view of the electronic form is customized for the user by including, in the customized view, the interactive element. The view of the customized electronic form is then displayed by the computing device.
FILED Wednesday, March 04, 2020
APPL NO 16/808448
ART UNIT 2144 — Graphical User Interface and Document Processing
CURRENT CPC
Electric Digital Data Processing
G06F 40/103 (20200101)
G06F 40/174 (20200101) Original (OR) Class
G06F 40/186 (20200101)
G06F 40/197 (20200101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 10/20 (20180101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11244452 Castro-Gonzalez et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  Universidad Politecnica De Madrid (Madrid, Spain)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Carlos Castro-Gonzalez (Cambridge, Massachusetts);  Ian Butterworth (Cambridge, Massachusetts);  Aurelien Bourquard (Cambridge, Massachusetts);  Alvaro Sanchez-Ferro (Madrid, Spain);  Jason Tucker-Schwartz (Melrose, Massachusetts);  Alberto Pablo-Trinidad (Madrid, Spain);  Maria J. Ledesma-Carbayo (Madrid, Spain);  Tom Vettenburg (Dundee, United Kingdom)
ABSTRACT A system for non-invasive hematological measurements includes a platform to receive a body portion of a user and an imaging device to acquire a set of images of a capillary bed in the body portion. For each image, a controller detects one or more capillaries in the body portion of the finger to identify a first set of capillaries by estimating one or more attributes of each capillary (e.g., structural attributes, flow attributes, imaging attributes, or combinations thereof), wherein at least one attribute of each capillary meets a predetermined criterion. The controller also identifies a second set of capillaries from the first set of capillaries such that each capillary of the second set of capillaries is visible in a predetermined number of images of the set of images.
FILED Tuesday, October 16, 2018
APPL NO 16/162006
ART UNIT 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0261 (20130101)
A61B 5/489 (20130101)
A61B 5/1455 (20130101)
A61B 5/6826 (20130101)
A61B 5/7203 (20130101)
A61B 5/7267 (20130101)
A61B 5/14546 (20130101)
A61B 2576/02 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/66 (20130101)
G06K 9/00885 (20130101)
G06K 2009/00932 (20130101)
G06K 2009/00939 (20130101)

Image Data Processing or Generation, in General
G06T 7/0014 (20130101) Original (OR) Class
G06T 2207/10016 (20130101)
G06T 2207/10152 (20130101)
G06T 2207/20081 (20130101)
G06T 2207/20084 (20130101)
G06T 2207/30101 (20130101)

Technologies for Adaptation to Climate Change
Y02A 90/10 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 11241188 Widge et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts);  Trustees of Boston University (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts);  Trustees of Boston University (Boston, Massachusetts)
INVENTOR(S) Alik Widge (Somerville, Massachusetts);  Emad Eskandar (Swampscott, Massachusetts);  Darin Dougherty (Wellesley, Massachusetts);  Uri Tzvi Eden (Medford, Massachusetts);  Xinyi Deng (Boston, Massachusetts);  Ali Yousefi (Brookline, Massachusetts);  Angelique Paulk (Brighton, Massachusetts)
ABSTRACT A system and methods for monitoring and controlling a mental state of a subject are provided. In some aspects, a method includes receiving physiological and behavioral data acquired using the plurality of sensors while the subject is performing a task, and applying, using the data, a state-space framework to determine a plurality of decoder parameters correlating brain activity and behavior with a mental state of the subject. The method also includes identifying the mental state of the subject using the decoder parameters, and generating a report indicating the mental state of the subject. In some aspects, the method further includes generating, based on the identified mental state, a brain stimulation to treat a brain condition of the subject.
FILED Thursday, June 30, 2016
APPL NO 15/740975
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/162 (20130101)
A61B 5/316 (20210101)
A61B 5/377 (20210101)
A61B 5/4064 (20130101)
A61B 5/4088 (20130101) Original (OR) Class
A61B 2560/0238 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/36139 (20130101)

Computer Systems Based on Specific Computational Models
G06N 7/005 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 15/00 (20180101)
G16H 20/70 (20180101)
G16H 50/20 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241190 Viswanath et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S) Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S) Satish Viswanath (Beachwood, Ohio);  Iulia Barbur (Akron, Ohio)
ABSTRACT Embodiments discussed herein facilitate predicting response to therapy in Crohn's disease. A first set of embodiments discussed herein relates to accessing a radiological image of a region of tissue demonstrating Crohn's disease associated with a patient; defining a mesenteric fat region by segmenting mesenteric fat represented in the radiological image; extracting a set of radiomic features from the mesenteric fat region; providing the set of radiomic features to a machine learning classifier configured to compute a probability of response to therapy in Crohn's disease based, at least in part, on the set of radiomic features; receiving, from the machine learning classifier, a probability that the region of tissue will respond to therapy; generating a classification of the patient as a responder or non-responder based, at least in part, on the probability; and displaying the classification.
FILED Monday, September 16, 2019
APPL NO 16/571454
ART UNIT 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0037 (20130101)
A61B 5/4255 (20130101) Original (OR) Class

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/6231 (20130101)

Computer Systems Based on Specific Computational Models
G06N 7/046 (20130101)
G06N 20/00 (20190101)

Image Data Processing or Generation, in General
G06T 7/11 (20170101)
G06T 7/0012 (20130101)
G06T 2207/10088 (20130101)
G06T 2207/30028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241194 Reifman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Secretary of the Army (SECARMY)
APPLICANT(S) The Government of the United States, as represented by the Secretary of the Army (Ft. Detrick, Maryland)
ASSIGNEE(S) The Government of the United States, as represented by the Secretary of the Army (Fort Detrick, Maryland)
INVENTOR(S) Jaques Reifman (New Market, Maryland);  Jianbo Liu (Lexington, Virginia);  Nancy Wesensten (Silver Spring, Maryland);  Thomas Balkin (Ellicott City, Maryland);  Sridhar Ramakrishnan (Frederick, Maryland);  Maxim Y. Khitrov (Rockville, Maryland)
ABSTRACT A system, method and apparatus is disclosed, comprising a biomathetical model for optimizing cognitive performance in the face of sleep deprivation that integrates novel and nonobvious biomathematical models for quantifying performance impairment for both chronic sleep restriction and total sleep deprivation; the dose-dependent effects of caffeine on human vigilance; and the pheonotypical response of a particular user to caffeine dosing, chronic sleep restriction and total sleep deprivation in user-friendly software application which itself may be part of a networked system.
FILED Wednesday, June 08, 2016
APPL NO 15/580907
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/00 (20130101)
A61B 5/02 (20130101)
A61B 5/11 (20130101)
A61B 5/18 (20130101)
A61B 5/103 (20130101)
A61B 5/113 (20130101)
A61B 5/162 (20130101)
A61B 5/165 (20130101)
A61B 5/0255 (20130101)
A61B 5/486 (20130101) Original (OR) Class
A61B 5/1118 (20130101)
A61B 5/4806 (20130101)
A61B 5/4839 (20130101)
A61B 5/4857 (20130101)
A61B 5/6898 (20130101)
A61B 5/7225 (20130101)
A61B 5/7275 (20130101)
A61B 5/7435 (20130101)
A61B 5/7475 (20130101)
A61B 2503/20 (20130101)
A61B 2560/0475 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 15/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241380 Freeman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) William Freeman (Del Mar, California);  Michael J. Sailor (La Jolla, California);  Lingyun Cheng (San Diego, California);  Frederique Cunin (Montpellier, France);  Emily Anglin (San Diego, California);  Yang Yang Li (Hong Kong, China Hong Kong)
ABSTRACT A minimally invasive controlled drug delivery system for delivering a particular drug or drugs to a particular location of the eye, the system including a porous film template having pores configured and dimensioned to at least partially receive at least one drug therein, and wherein the template is dimensioned to be delivered into or onto the eye.
FILED Monday, November 06, 2017
APPL NO 15/804856
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 9/0017 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0048 (20130101) Original (OR) Class
A61K 9/0051 (20130101)
A61K 9/1611 (20130101)
A61K 9/7007 (20130101)
A61K 31/573 (20130101)
A61K 47/24 (20130101)
A61K 47/26 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 27/02 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241394 Zhang et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Liangfang Zhang (San Diego, California);  Che-Ming Jack Hu (Novato, California);  Ronnie H. Fang (San Diego, California);  Brian T. Luk (San Diego, California);  Kuei-Chun Wang (San Diego, California);  Shu Chien (La Jolla, California)
ABSTRACT The present invention relates to prevention and/or treatment of diseases or disorders associated with a damaged or leaky vasculature in a subject. The present invention provides for methods, combinations and pharmaceutical compositions for preventing and/or treating a disease or disorder associated with a damaged or leaky vasculature in a subject, using, inter alia, an effective amount of a nanoparticle comprising an inner core comprising a non-cellular material, an outer surface comprising a cellular membrane derived from a platelet; and optionally an agent for preventing, treating, diagnosing, or prognosing the disease or disorder and/or monitoring prevention or treatment of the disease or disorder. Exemplary diseases or disorders include hemorrhage (bleeding), cardiovascular diseases or disorders, diseases or disorders associated with narrowing of a blood vessel, tumors or cancers.
FILED Tuesday, June 07, 2016
APPL NO 15/737566
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5153 (20130101)
A61K 9/5169 (20130101)
A61K 9/5176 (20130101) Original (OR) Class
A61K 31/337 (20130101)
A61K 47/6901 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 7/04 (20180101)
A61P 9/00 (20180101)
A61P 35/00 (20180101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)
B82Y 30/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241511 Mahmood et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Umar Mahmood (Winchester, Massachusetts);  Benjamin Larimer (Woburn, Massachusetts)
ABSTRACT Provided herein are compositions useful for imaging HER3. An exemplary composition provided herein is useful as a radiotracer for position emission tomography (PET) imaging. Methods of imaging HER3 and combination therapies comprising the HER3 imaging agents are also provided.
FILED Friday, December 29, 2017
APPL NO 16/475020
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 51/088 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242244 Plochowietz et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Palo Alto Research Center Incorporated (Palo Alto, California)
ASSIGNEE(S) Palo Alto Research Center Incorporated (Palo Alto, California)
INVENTOR(S) Anne Plochowietz (Palo Alto, California);  Bradley Rupp (San Francisco, California);  Jengping Lu (Fremont, California);  Julie A. Bert (East Palo Alto, California);  Lara S. Crawford (Los Altos, California);  Sourobh Raychaudhuri (Mountain View, California);  Eugene M. Chow (Palo Alto, California);  Matthew Shreve (Mountain View, California);  Sergey Butylkov (Oakland, California)
ABSTRACT Disclosed are methods and systems of controlling the placement of micro-objects on the surface of a micro-assembler. Control patterns may be used to cause electrodes of the micro-assembler to generate dielectrophoretic (DEP) and electrophoretic (EP) forces which may be used to manipulate, move, position, or orient one or more micro-objects on the surface of the micro-assembler. The control patterns may be part of a library of control patterns.
FILED Monday, December 31, 2018
APPL NO 16/237419
ART UNIT 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems
B81C 99/002 (20130101) Original (OR) Class

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/67271 (20130101)
H01L 21/67294 (20130101)
H01L 24/95 (20130101)
H01L 2224/95133 (20130101)
H01L 2224/95145 (20130101)
H01L 2924/1461 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 29/49131 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242262 Ravichandran et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army
Research, Development and Engineering Command (RDECOM)
APPLICANT(S) Texas Biochemicals Inc. (College Station, Texas)
ASSIGNEE(S) TEXAS BIOCHEMICALS INC. (, None)
INVENTOR(S) Duraiswamy Ravichandran (College Station, Texas);  V S Reddy Channu (College Station, Texas)
ABSTRACT A method is provided for producing an article which is transparent to IR wavelength in the region of 4 μm to 9 μm. The method includes the steps of (a) Producing ultra-fine powders of ZnS, (b) followed by pretreatment of the ultra-fine powders under reduced gas conditions including H2, H2S, N2, Ar and mixtures there of (c) followed by vacuum (3×10−6 torr) treatment to remove oxygen and sulfates adsorbed to the surface disposing a plurality of nano-particles on a substrate, wherein said nanoparticles comprise ZnS with ultra-high purity of cubic phase; (b) subjecting the nano-particles to spark plasma sintering thereby producing a sintered ZnS product with IR transmission reaching 75% in the wavelength range of 4 μm to 9 μm.
FILED Tuesday, December 27, 2016
APPL NO 15/390853
ART UNIT 1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster
B28B 3/003 (20130101)
B28B 11/243 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 19/007 (20130101)

Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 9/08 (20130101)
C01G 11/02 (20130101) Original (OR) Class

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/72 (20130101)
C01P 2002/82 (20130101)
C01P 2004/03 (20130101)
C01P 2004/61 (20130101)
C01P 2004/64 (20130101)
C01P 2006/60 (20130101)
C01P 2006/90 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242367 Lawrence et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
United States Army (USA)
National Science Foundation (NSF)
APPLICANT(S) Silk Technologies, Ltd. (Plymouth, Minnesota)
ASSIGNEE(S) Silk Technologies, Ltd. (Plymouth, Minnesota)
INVENTOR(S) Brian D. Lawrence (Tampa, Florida);  David W. Infanger (Maple Grove, Minnesota)
ABSTRACT Described herein are methods for reducing inflammation by administration of an effective amount of silk-derived proteins (SDP) or a fraction thereof to a subject having an inflammatory condition. The methods include the treatment of inflammatory conditions and wounds, including corneal wounds, comprising the topical administration of an effective amount of SDP material as described herein.
FILED Saturday, August 12, 2017
APPL NO 16/324844
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/14 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0048 (20130101)
A61K 38/00 (20130101)
A61K 38/012 (20130101)
A61K 47/02 (20130101)
A61K 47/10 (20130101)
A61K 47/26 (20130101)
A61K 47/34 (20130101)
A61K 47/38 (20130101)
A61K 47/42 (20130101)
A61K 47/183 (20130101)

Peptides
C07K 14/43586 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242375 Adusumilli et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Congressionally Directed Medical Research Programs (CDMRP)
APPLICANT(S) Memorial Sloan Kettering Cancer Center (New York, New York)
ASSIGNEE(S) Memorial Sloan Kettering Cancer Center (New York, New York)
INVENTOR(S) Prasad S. Adusumilli (New York, New York);  Michel Sadelain (New York, New York)
ABSTRACT Disclosed herein are cells that are immune cells or precursor cells thereof, which cells recombinantly express a chimeric antigen receptor (CAR), and a dominant negative form of an inhibitor of a cell-mediated immune response of the immune cell, wherein the CAR binds to a cancer antigen. Also disclosed herein are T cells that recognize and are sensitized to a cancer antigen, which T cells recombinantly express a dominant negative form of an inhibitor of a T cell-mediated immune response. Additionally provided are methods of using such cells to treat cancer in a subject in need thereof.
FILED Friday, September 02, 2016
APPL NO 15/757276
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101)
A61K 35/28 (20130101)
A61K 38/00 (20130101)
A61K 38/177 (20130101)
A61K 38/193 (20130101)
A61K 38/193 (20130101)
A61K 38/1774 (20130101)
A61K 38/2013 (20130101)
A61K 38/2013 (20130101)
A61K 38/4873 (20130101)
A61K 39/0011 (20130101)
A61K 39/00117 (20180801)
A61K 39/00118 (20180801)
A61K 39/001104 (20180801)
A61K 39/001106 (20180801)
A61K 39/001109 (20180801)
A61K 39/001112 (20180801)
A61K 39/001113 (20180801)
A61K 39/001114 (20180801)
A61K 39/001119 (20180801)
A61K 39/001122 (20180801)
A61K 39/001124 (20180801)
A61K 39/001126 (20180801)
A61K 39/001128 (20180801)
A61K 39/001129 (20180801)
A61K 39/001153 (20180801)
A61K 39/001157 (20180801)
A61K 39/001166 (20180801)
A61K 39/001168 (20180801)
A61K 39/001171 (20180801)
A61K 39/001174 (20180801)
A61K 39/001182 (20180801)
A61K 39/001186 (20180801)
A61K 39/001188 (20180801)
A61K 39/001192 (20180801)
A61K 39/001193 (20180801)
A61K 39/001195 (20180801)
A61K 39/39558 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/7051 (20130101) Original (OR) Class
C07K 14/70503 (20130101)
C07K 14/70517 (20130101)
C07K 14/70521 (20130101)
C07K 14/70578 (20130101)
C07K 16/30 (20130101)
C07K 16/3069 (20130101)
C07K 2317/622 (20130101)
C07K 2319/02 (20130101)
C07K 2319/03 (20130101)
C07K 2319/33 (20130101)
C07K 2319/74 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0636 (20130101)
C12N 5/0638 (20130101)
C12N 9/6472 (20130101)
C12N 2510/00 (20130101)

Enzymes
C12Y 304/22062 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242378 Bornholdt et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) MAPP BIOPHARMACEUTICAL, INC. (San Diego, California);  Albert Einstein College of Medicine (Bronx, New York);  Adimab, LLC (Lebanon, New Hampshire)
ASSIGNEE(S) MAPP BIOPHARMACEUTICAL, INC. (San Diego, California);  ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York);  ADIMAB, LLC (Lebanon, New Hampshire)
INVENTOR(S) Zachary A. Bornholdt (Encinitas, California);  Larry Zeitlin (San Diego, California);  Kartik Chandran (Brooklyn, New York);  Anna Wec (Lebanon, New Hampshire);  Laura Walker (Norwich, Vermont)
ABSTRACT Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially, similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.
FILED Tuesday, June 09, 2020
APPL NO 16/896980
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/42 (20130101)
A61K 2039/55 (20130101)
A61K 2039/57 (20130101)
A61K 2039/62 (20130101)
A61K 2039/505 (20130101)
A61K 2039/545 (20130101)
A61K 2039/6075 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)

Peptides
C07K 16/10 (20130101) Original (OR) Class
C07K 2317/76 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242379 Bornholdt et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) MAPP BIOPHARMACEUTICAL, INC. (San Diego, California);  Albert Einstein College of Medicine (Bronx, New York);  Adimab, LLC (Lebanon, New Hampshire)
ASSIGNEE(S) MAPP BIOPHARMACEUTICAL, INC. (San Diego, California);  ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York);  ADIMAB, LLC (Lebanon, New Hampshire)
INVENTOR(S) Zachary A. Bornholdt (Encinitas, California);  Larry Zeitlin (San Deigo, California);  Kartik Chandran (Brooklyn, New York);  Anna Wec (Lebanon, New Hampshire);  Laura Walker (Norwich, Vermont)
ABSTRACT Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.
FILED Tuesday, June 09, 2020
APPL NO 16/896991
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/42 (20130101)
A61K 2039/55 (20130101)
A61K 2039/57 (20130101)
A61K 2039/62 (20130101)
A61K 2039/505 (20130101)
A61K 2039/545 (20130101)
A61K 2039/6075 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)

Peptides
C07K 16/10 (20130101) Original (OR) Class
C07K 2317/76 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242553 Lieberman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Children's Medical Center Corporation (Boston, Massachusetts)
ASSIGNEE(S) Children's Medical Center Corporation (Boston, Massachusetts)
INVENTOR(S) Judy Lieberman (Brookline, Massachusetts);  Shen Mynn Tan (Newton, Massachusetts)
ABSTRACT The present invention provides systems and methods for identifying, isolating, and/or characterizing microRNAs, their targets, and microRNA response elements, and for predicting their biological function.
FILED Friday, January 17, 2014
APPL NO 14/761791
ART UNIT 1699 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)
C12N 15/1006 (20130101)
C12N 2310/141 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6816 (20130101) Original (OR) Class
C12Q 1/6816 (20130101)
C12Q 1/6886 (20130101)
C12Q 2521/327 (20130101)
C12Q 2525/207 (20130101)
C12Q 2527/125 (20130101)
C12Q 2600/178 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242572 Wang et al.
FUNDED BY
Department of Defense (DOD)
Uniformed Services University of the Health Sciences (USUHS)
Henry M Jackson Foundation for the Advancement of Military Medicine, Inc (HJF)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland)
ASSIGNEE(S) THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (Bethesda, Maryland)
INVENTOR(S) Linfa Wang (Wandana Heights, Australia);  Glenn A. Marsh (Leopold, Australia);  Hume Field (Ormiston, Australia);  Christopher Broder (Silver Spring, Maryland)
ABSTRACT The present disclosure is directed towards a virus, called Cedar Virus, and its methods of use.
FILED Tuesday, March 12, 2019
APPL NO 16/351380
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/00 (20130101)
A61K 39/12 (20130101)
A61K 2039/543 (20130101)

Peptides
C07K 14/005 (20130101)
C07K 16/1027 (20130101)
C07K 2317/76 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2760/18221 (20130101)
C12N 2760/18222 (20130101)
C12N 2760/18231 (20130101)
C12N 2760/18234 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/70 (20130101)
C12Q 1/701 (20130101) Original (OR) Class
C12Q 2600/136 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242576 Wengrenovich et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
ASSIGNEE(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S) Nicholas J. Wengrenovich (Evanston, Illinois);  Gregory B. Olson (Riverswood, Illinois)
ABSTRACT An optimized Gamma-prime (γ′) strengthened austenitic transformation induced plasticity (TRIP) steel comprises a composition designed and processed such that the optimized γ′ strengthened austenitic TRIP steel meets property objectives comprising a yield strength of 896 MPa (130 ksi), and an austenite stability designed to have Msσ(sh)=−40° C., wherein Msσ(sh) is a temperature for shear, and wherein the property objectives are design specifications of the optimized γ′ strengthened austenitic TRIP steel. The optimized γ′ strengthened austenitic TRIP steel is Blastalloy TRIP 130.
FILED Monday, April 10, 2017
APPL NO 15/483559
ART UNIT 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering
C21D 6/02 (20130101) Original (OR) Class
C21D 6/004 (20130101)
C21D 7/13 (20130101)
C21D 2211/001 (20130101)
C21D 2211/004 (20130101)

Alloys
C22C 38/06 (20130101)
C22C 38/44 (20130101)
C22C 38/46 (20130101)
C22C 38/50 (20130101)
C22C 38/54 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11243056 Rastegar et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
United States Army (USA)
APPLICANT(S) Omnitek Partners LLC (Ronkonkoma, New York)
ASSIGNEE(S) OMNITEK PARTNERS LLC (Ronkonkoma, New York)
INVENTOR(S) Jahangir S Rastegar (Stony Brook, New York);  Jacques Fischer (Sound Beach, New York)
ABSTRACT A munition including: a control surface actuation device including: an actuator having two or more pistons, each of the pistons being movable between an extended and retracted position, the retracted position resulting from an activation of each of the two or more pistons; and a movable rack having a pocket corresponding to each of the two or more pistons, each pocket being engageable with a corresponding portion of each of the two or more pistons, a distance between the pockets being different than a distance between the portions of the two or more pistons, such that activation of the portion into the corresponding pocket sequentially translates the rack; and a control surface operatively connected to the rack such that translation of the rack rotates the control surface.
FILED Tuesday, August 25, 2020
APPL NO 17/002623
ART UNIT 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 10/18 (20130101)
F42B 10/64 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11243200 Shih et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Congressionally Directed Medical Research Programs (CDMRP)
United States Army (USA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Drexel University (Philadelphia, Pennsylvania)
ASSIGNEE(S) Drexel University (Philadelphia, Pennsylvania)
INVENTOR(S) Wan Y. Shih (Bryn Mawr, Pennsylvania);  Wei Wu (Philadelphia, Pennsylvania);  Wei-Heng Shih (Bryn Mawr, Pennsylvania);  Mehmet Cagri Soylu (Melikgazi, Turkey);  Haitao Guo (Carmel, Indiana);  Suresh G. Joshi (Secane, Pennsylvania);  Ceyhun Ekrim Kirimli (Thunder Bay, Canada);  Ying-Hsiu Su (Audubon, Pennsylvania)
ABSTRACT A piezoelectric plate sensor comprising a piezoelectric layer; two electrodes; and an insulation layer. The insulation layer is produced by soaking the piezoelectric layer and two electrodes in a mercaptopropyltrimethoxysilane solution with an amount of water from 0.1 v/v. % to about 1 v/v % and at pH from about 8 to about 150 for a period from about 8 to about 15 hours, and the mercaptopropyltrimethoxysilane solution has a concentration of mercaptopropyltrimethoxysilane from about 0.01 v/v % to about 0.5 v/v %. A method of detecting a biomolecule in a sample using the piezoelectric plate sensor in particular, that of detecting a genetic marker with PCR sensitivity and specificity without the need of DNA isolation or amplification is also provided. The piezoelectric plate sensor may be used to diagnose various diseases including breast cancer, myocardial infarction, diarrhea, Clostridium difficile infection, and hepatitis B infection.
FILED Tuesday, December 11, 2018
APPL NO 16/216848
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6825 (20130101)
C12Q 1/6825 (20130101)
C12Q 2565/607 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 29/022 (20130101)
G01N 29/036 (20130101)
G01N 33/54373 (20130101) Original (OR) Class
G01N 33/54393 (20130101)
G01N 2291/0255 (20130101)
G01N 2291/0256 (20130101)
G01N 2291/0427 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11243368 Rottle et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Secretary of the Navy (SECNAV)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Keyport, Washington)
INVENTOR(S) Brandon Rottle (Tacoma, Washington);  Mitch Van Epps (Seabeck, Washington);  Steven Kyle Denton (Wauna, Washington);  Robert Lutes (Silverdale, Washington)
ABSTRACT A fiber optic cable clamp has two identical halves that snap together forming the clamp. The clamp can be made of thermoplastic materials and designed to permit stacking of multiple clamps without damaging the cables.
FILED Wednesday, April 22, 2020
APPL NO 16/873502
ART UNIT 2874 — Optics
CURRENT CPC
Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General
F16L 3/10 (20130101)
F16L 3/1025 (20130101)

Optical Elements, Systems, or Apparatus
G02B 6/3616 (20130101)
G02B 6/4471 (20130101) Original (OR) Class

Installation of Electric Cables or Lines, or of Combined Optical and Electric Cables or Lines
H02G 3/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11244003 Abeloe et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Warfare Center (NAWC)
APPLICANT(S) Centauri, LLC (Chantilly, California)
ASSIGNEE(S) CENTAURI, LLC (Chantilly, Virginia)
INVENTOR(S) Kenneth A. Abeloe (Carlsbad, California);  Dennis Hsu (San Diego, California)
ABSTRACT Systems and methods for full motion video search are provided. In one aspect, a method includes receiving one or more search terms. The search terms include one or more of a characterization of the amount of man-made features in a video image and a characterization of the amount of natural features in the video image. The method further includes searching a full motion video database based on the one or more search terms.
FILED Monday, November 04, 2019
APPL NO 16/673720
ART UNIT 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Electric Digital Data Processing
G06F 16/113 (20190101)
G06F 16/783 (20190101)
G06F 16/7837 (20190101)
G06F 16/7847 (20190101)
G06F 16/7867 (20190101) Original (OR) Class

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00637 (20130101)
G06K 9/00718 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11244050 Nataraj et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Mayachitra, Inc. (Santa Barbara, California)
ASSIGNEE(S) Mayachitra, Inc. (Santa Barbara, California)
INVENTOR(S) Lakshmanan Nataraj (Goleta, California);  Bangalore S. Manjunath (Santa Barbara, California);  Shivkumar Chandrasekaran (Santa Barbara, California)
ABSTRACT Methods, systems and computer programs are presented for classifying malware using audio signal processing. One method includes an operation for converting a non-audio data file to an audio signal. Audio features are extracted from the audio signal and are used to classify the non-audio data file.
FILED Monday, December 03, 2018
APPL NO 16/207586
ART UNIT 2433 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/55 (20130101)
G06F 21/56 (20130101)
G06F 21/57 (20130101)
G06F 21/562 (20130101)
G06F 21/564 (20130101)
G06F 21/565 (20130101) Original (OR) Class
G06F 21/566 (20130101)
G06F 2221/034 (20130101)

Computer Systems Based on Specific Computational Models
G06N 20/00 (20190101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/26 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11244160 Bushmitch et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Secretary of the Army (SECARMY)
APPLICANT(S) The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S) The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Dennis Bushmitch (Somerset, New Jersey);  Michael Badger (Ocean Grove, New Jersey)
ABSTRACT Various embodiments associated with a composite image are described. In one embodiment, a handheld device comprises a launch component configured to cause a launch of a projectile. The projectile is configured to capture a plurality of images. Individual images of the plurality of images are of different segments of an area. The system also comprises an image stitch component configured to stitch the plurality of images into a composite image. The composite image is of a higher resolution than a resolution of individual images of the plurality of images.
FILED Friday, September 23, 2016
APPL NO 15/273924
ART UNIT 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Aeroplanes; Helicopters
B64C 39/024 (20130101)
B64C 2201/08 (20130101)
B64C 2201/123 (20130101)
B64C 2201/127 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/0063 (20130101) Original (OR) Class
G06K 9/00771 (20130101)
G06K 2009/2045 (20130101)

Image Data Processing or Generation, in General
G06T 3/4038 (20130101)
G06T 3/4053 (20130101)
G06T 5/50 (20130101)
G06T 7/33 (20170101)
G06T 7/38 (20170101)
G06T 11/60 (20130101)
G06T 2207/10032 (20130101)
G06T 2207/20221 (20130101)
G06T 2207/30181 (20130101)
G06T 2207/30212 (20130101)

Pictorial Communication, e.g Television
H04N 5/28 (20130101)
H04N 5/2624 (20130101)
H04N 5/23238 (20130101)
H04N 5/23293 (20130101)
H04N 7/185 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11245157 Winter et al.
FUNDED BY
Department of Defense (DOD)
Missile Defense Agency (MDA)
APPLICANT(S) INNOSENSE LLC (Torrance, California)
ASSIGNEE(S) INNOSENSE LLC (Torrance, California)
INVENTOR(S) Raymond Winter (Riverside, California);  Maksudul M. Alam (Glendora, California);  Uma Sampathkumaran (Torrance, California);  John Abolencia (Los Angeles, California)
ABSTRACT Methods for producing ceramic films Yttria Stabilized Zirconia (3YSZ) and aluminum titanate (Al2TiO5), and the physical properties of these films are described. The films produced have thicknesses and integrity suitable for handling and corrosion resistance to electrolytes, porosity, ion permeability and electrical resistivity suitable for use as separators between positive and negative layers for forming electrical batteries, particularly lithium batteries.
FILED Thursday, February 28, 2019
APPL NO 16/289026
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/052 (20130101)
H01M 10/0561 (20130101)
H01M 10/0563 (20130101)
H01M 10/0587 (20130101)
H01M 10/4235 (20130101)
H01M 50/403 (20210101)
H01M 50/431 (20210101) Original (OR) Class
H01M 50/449 (20210101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11245330 Giuliano et al.
FUNDED BY
Department of Defense (DOD)
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) David M. Giuliano (Cambridge, Massachusetts);  David J. Perreault (Cambridge, Massachusetts);  Robert C. N. Pilawa-Podgurski (Cambridge, Massachusetts)
ABSTRACT A converter circuit and related technique for providing high power density power conversion includes a reconfigurable switched capacitor transformation stage coupled to a magnetic converter (or regulation) stage. The circuits and techniques achieve high performance over a wide input voltage range or a wide output voltage range. The converter can be used, for example, to power logic devices in portable battery operated devices.
FILED Monday, June 29, 2020
APPL NO 16/915051
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 1/007 (20210501)
H02M 3/07 (20130101)
H02M 3/155 (20130101)
H02M 3/158 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11245387 Grout
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Kevin Grout (Chandler, Arizona)
ASSIGNEE(S) Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) Kevin Grout (Chandler, Arizona)
ABSTRACT A system for generating an RFPWM signal comprises a delta sigma modulator having a plurality of outputs, a phase-locked loop comprising a plurality of phase quantization outputs, at least one multiplexer having a plurality of signal inputs, a plurality of selector inputs, and at least one output, the signal inputs communicatively connected to the phase quantization outputs of the phase-locked loop and the selector inputs electrically connected to the outputs of the delta sigma modulator, and a driver having an input communicatively connected to the output of the multiplexer and an output generating an RFPWM signal. A method of generating an RFPWM signal is also described.
FILED Thursday, January 21, 2021
APPL NO 17/154437
ART UNIT 2849 — Electrical Circuits and Systems
CURRENT CPC
Pulse Technique
H03K 3/012 (20130101) Original (OR) Class
H03K 3/017 (20130101)
H03K 19/20 (20130101)

Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses
H03L 7/08 (20130101)

Coding; Decoding; Code Conversion in General
H03M 3/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11245743 Mitchell et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Architecture Technology Corporation (Minneapolis, Minnesota)
ASSIGNEE(S) Architecture Technology Corporation (Minneapolis, Minnesota)
INVENTOR(S) Tyler J. Mitchell (Ithaca, New York);  Judson Powers (Ithaca, New York);  Scott Aloisio (Willseyville, New York);  Matthew A. Stillerman (Ithaca, New York);  Valentino Felipe (Campbell, California)
ABSTRACT In general, this disclosure describes media stream transmission techniques for a computing device. The computing device may capture an image of a local background environment. The computing device may record a first media stream that includes at least a portion of the image of the background environment and at least one movement of at least one object through the background environment. The computing device may remove the image of the background environment from the first media stream to create a second media stream that includes the movement of the object without the image of the background environment. The computing device may determine a bandwidth of a network over which the second media stream will be transmitted and perform further alterations to the second media stream if the current bandwidth is less than a bandwidth threshold level in order to reduce the bandwidth needed to transmit the second media stream.
FILED Friday, September 25, 2020
APPL NO 17/032454
ART UNIT 2445 — Computer Networks
CURRENT CPC
Image Data Processing or Generation, in General
G06T 7/194 (20170101)
G06T 2207/10021 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 40/67 (20180101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 47/801 (20130101)
H04L 65/80 (20130101) Original (OR) Class
H04L 65/601 (20130101)
H04L 65/4084 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 11241014 Finn et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia);  M. G. Finn (Atlanta, Georgia);  Jennifer Marie Beveridge (Atlanta, Georgia);  Allison Geoghan Aioub (Atlanta, Georgia);  Zhishuai Geng (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) M. G. Finn (Atlanta, Georgia);  Jennifer Marie Beveridge (Atlanta, Georgia);  Allison Geoghan Aioub (Atlanta, Georgia);  Zhishuai Geng (Atlanta, Georgia)
ABSTRACT Disclosed are antimicrobial articles and surfaces, as well as methods of making such articles and surfaces.
FILED Wednesday, May 31, 2017
APPL NO 16/305534
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 25/10 (20130101)
A01N 25/10 (20130101)
A01N 33/12 (20130101)
A01N 43/40 (20130101)
A01N 43/40 (20130101)
A01N 43/46 (20130101)
A01N 43/90 (20130101) Original (OR) Class

Heterocyclic Compounds
C07D 495/08 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 8/32 (20130101)
C08F 120/60 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 5/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241380 Freeman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) William Freeman (Del Mar, California);  Michael J. Sailor (La Jolla, California);  Lingyun Cheng (San Diego, California);  Frederique Cunin (Montpellier, France);  Emily Anglin (San Diego, California);  Yang Yang Li (Hong Kong, China Hong Kong)
ABSTRACT A minimally invasive controlled drug delivery system for delivering a particular drug or drugs to a particular location of the eye, the system including a porous film template having pores configured and dimensioned to at least partially receive at least one drug therein, and wherein the template is dimensioned to be delivered into or onto the eye.
FILED Monday, November 06, 2017
APPL NO 15/804856
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 9/0017 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0048 (20130101) Original (OR) Class
A61K 9/0051 (20130101)
A61K 9/1611 (20130101)
A61K 9/7007 (20130101)
A61K 31/573 (20130101)
A61K 47/24 (20130101)
A61K 47/26 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 27/02 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241671 Petruska et al.
FUNDED BY
National Science Foundation (NSF)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) Melissa A. Petruska (Newtown, Connecticut);  Trevor E. James (Plantsville, Connecticut);  James D. Carruthers (Reno, Nevada);  Peter C. Van Buskirk (Newtown, Connecticut);  Jeffrey F. Roeder (Brookfield, Connecticut)
ASSIGNEE(S) Sonata Scientific LLC (Danbury, Connecticut)
INVENTOR(S) Melissa A. Petruska (Newtown, Connecticut);  Trevor E. James (Plantsville, Connecticut);  James D. Carruthers (Reno, Nevada);  Peter C. Van Buskirk (Newtown, Connecticut);  Jeffrey F. Roeder (Brookfield, Connecticut)
ABSTRACT Monolithic composite photocatalysts for fluid purification, chemical transformations, and surface sterilization are disclosed. The monolithic composite photocatalysts comprise a photoactive nanocrystal component and a non-photoactive porous support. Photocatalytic fluid purification systems that contact an impurity-containing fluid with the subject monolithic composite photocatalysts are also disclosed.
FILED Tuesday, November 12, 2019
APPL NO 16/680495
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 2/10 (20130101)
A61L 2/16 (20130101)
A61L 2/084 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 21/063 (20130101) Original (OR) Class
B01J 35/004 (20130101)
B01J 35/04 (20130101)
B01J 35/006 (20130101)
B01J 35/08 (20130101)
B01J 35/023 (20130101)
B01J 35/1014 (20130101)
B01J 35/1019 (20130101)
B01J 35/1023 (20130101)
B01J 35/1061 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 35/00 (20130101)
B82Y 40/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241681 Veige et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Adam S. Veige (Gainesville, Florida);  Stella Almeida Gonsales (Gainesville, Florida)
ABSTRACT A tetraanionic OCO pincer ligand metal-oxo-alkylidene complex is prepared from a trianionic pincer ligand supported metal-alkylidyne. The metal can be tungsten or other group 5-7 transition metal. The tetraanionic pincer ligand metal-oxo-alkylidene complex, a trianionic OCO pincer ligand metal complex, or a trianionic ONO pincer ligand metal complex can be used to polymerize cycloalkenes. The poly(cycloalkene)s are predominantly cis-alkene macrocyclics.
FILED Monday, March 02, 2020
APPL NO 16/806054
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 31/223 (20130101) Original (OR) Class
B01J 31/2243 (20130101)
B01J 31/2265 (20130101)
B01J 31/2286 (20130101)
B01J 2231/14 (20130101)
B01J 2231/543 (20130101)
B01J 2531/66 (20130101)
B01J 2531/0244 (20130101)
B01J 2540/10 (20130101)
B01J 2540/225 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 11/00 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 4/69 (20130101)
C08F 4/78 (20130101)
C08F 4/69206 (20130101)
C08F 32/04 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 61/08 (20130101)
C08G 2261/13 (20130101)
C08G 2261/418 (20130101)
C08G 2261/3324 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242248 Groves et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) The Trustees of Princeton University (Princeton, New Jersey)
ASSIGNEE(S) The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S) John T. Groves (Princeton, New Jersey);  Roy Xiao (Princeton, New Jersey)
ABSTRACT Methods, kits, cartridges, and compounds related to generating chlorine dioxide by exposing ClO2to at least one of an iron porphyrin catalyst or an iron porphyrazine catalyst are described.
FILED Wednesday, May 01, 2019
APPL NO 16/400277
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 2/18 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 31/26 (20130101)
B01J 31/183 (20130101)
B01J 31/1815 (20130101)
B01J 31/2295 (20130101)
B01J 2531/025 (20130101)
B01J 2531/842 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 11/024 (20130101) Original (OR) Class

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/76 (20130101)
C02F 2103/023 (20130101)
C02F 2303/04 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 15/025 (20130101)

Production of Cellulose by Removing Non-cellulose Substances From Cellulose-containing Materials; Regeneration of Pulping Liquors; Apparatus Therefor
D21C 9/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242290 Faber et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Katherine T. Faber (Pasadena, California);  Julia A. Kornfield (Pasadena, California);  Noriaki Arai (Pasadena, California);  Orland Bateman (Pasadena, California);  Rustem F. Ismagilov (Pasadena, California)
ABSTRACT Provided herein are methods for making a freeze-cast material having a internal structure, the methods comprising steps of: determining the internal structure of the material, the internal structure having a plurality of pores, wherein: each of the plurality of pores has directionality; and the step of determining comprises: selecting a temperature gradient and a freezing front velocity to obtain the determined internal structure based on the selected temperature gradient and the selected freezing front velocity; directionally freezing a liquid formulation to form a frozen solid, the step of directionally freezing comprising: controlling the temperature gradient and the freezing front velocity to match the selected temperature gradient and the selected freezing front velocity during directionally freezing; wherein the liquid formulation comprises at least one solvent and at least one dispersed species; and subliming the at least one solvent out of the frozen solid to form the material.
FILED Friday, August 23, 2019
APPL NO 16/549954
ART UNIT 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 67/0051 (20130101)
B01D 69/02 (20130101)
B01D 71/024 (20130101)
B01D 2325/021 (20130101)
B01D 2325/26 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 35/04 (20130101)
B01J 35/1071 (20130101)
B01J 35/1076 (20130101)

Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 38/007 (20130101)
C04B 38/0038 (20130101)
C04B 38/0054 (20130101)
C04B 38/0093 (20130101)
C04B 38/0605 (20130101) Original (OR) Class

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/14 (20130101)
H01B 1/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242296 Dussault et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) NUtech Ventures (Lincoln, Nebraska)
ASSIGNEE(S) NUtech Ventures (Lincoln, Nebraska)
INVENTOR(S) Patrick H. Dussault (Lincoln, Nebraska);  Andrew Olson (Lincoln, Nebraska)
ABSTRACT Disclosed herein is a method of reducing or disproportionating peroxide, comprising combining an organic chalcogenide, an iron salt, and the peroxide in the presence of an additional reductant, which can be the organic chalcogenide. The method can be used to, e.g., prepare alcohols from peroxides and to disproportionate hydrogen peroxide into water and oxygen.
FILED Wednesday, July 17, 2019
APPL NO 16/514423
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
General Methods of Organic Chemistry; Apparatus Therefor
C07B 41/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242363 Veige et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Adam S. Veige (Gainesville, Florida);  Vineet K. Jakhar (Gainesville, Florida);  Muhammad Tariq Jan (Khyber Paktunkhwa, Pakistan)
ABSTRACT Disclosed are to metallocyclopropene complexes, methods of making same, methods for ring expansion metathesis polymerization, and polymers prepared by the methods for ring expansion metathesis polymerization.
FILED Friday, November 30, 2018
APPL NO 16/767697
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 11/00 (20130101) Original (OR) Class

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 132/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242367 Lawrence et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
United States Army (USA)
National Science Foundation (NSF)
APPLICANT(S) Silk Technologies, Ltd. (Plymouth, Minnesota)
ASSIGNEE(S) Silk Technologies, Ltd. (Plymouth, Minnesota)
INVENTOR(S) Brian D. Lawrence (Tampa, Florida);  David W. Infanger (Maple Grove, Minnesota)
ABSTRACT Described herein are methods for reducing inflammation by administration of an effective amount of silk-derived proteins (SDP) or a fraction thereof to a subject having an inflammatory condition. The methods include the treatment of inflammatory conditions and wounds, including corneal wounds, comprising the topical administration of an effective amount of SDP material as described herein.
FILED Saturday, August 12, 2017
APPL NO 16/324844
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/14 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0048 (20130101)
A61K 38/00 (20130101)
A61K 38/012 (20130101)
A61K 47/02 (20130101)
A61K 47/10 (20130101)
A61K 47/26 (20130101)
A61K 47/34 (20130101)
A61K 47/38 (20130101)
A61K 47/42 (20130101)
A61K 47/183 (20130101)

Peptides
C07K 14/43586 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11243029 Strongrich et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Andrew Strongrich (West Lafayette, Indiana);  Alina Alexeenko (West Lafayette, Indiana)
ABSTRACT A non-invasive method to monitor and control of lyophilization of a frozen product solution to remove solvents is disclosed which includes installing one or more wireless pressure sensors configured to fit into a lyophilization vial tray disposed in a lyophilization chamber having a plurality of product vials, wherein the wireless pressure are distributed among the product vials being lyophilized thereby providing spatial pressure variations, collecting the spatial pressure information from said wireless pressure sensors, calculating sublimation rate of the solution, and adjusting pressure and/or temperature within the lyophilization chamber such that the calculated sublimation rate stays within a predetermined envelope.
FILED Monday, April 27, 2020
APPL NO 16/859835
ART UNIT 3753 — Fluid Handling and Dispensing
CURRENT CPC
Drying Solid Materials or Objects by Removing Liquid Therefrom
F26B 5/06 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 25/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11243079 Das
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) KUTZTOWN UNIVERSITY OF PENNSYLVANIA (Kutztown, Pennsylvania)
ASSIGNEE(S) Kutztown University of Pennsylvania (Kutztown, Pennsylvania)
INVENTOR(S) Kunal Das (Reading, Pennsylvania)
ABSTRACT Embodiments relate to a sensor system configured to detect physical rotation, entire or relative, of one or more objects and/or their environment and/or proximity of a magnetic field, by measuring the degree of localization of a medium trapped in a ring-shaped artificial lattice. The lattice structure can be configured to comprise of lattice sites distributed with a lattice period around an azimuth of a closed ring. The site depths of the plurality of lattice sites can be configured to be modulated with a modulation period different from the lattice period to affect the onsite energies of each lattice site and the eigenstates of the system. Physical rotation of the sensor and/or the proximity of magnetic field will alter the localization properties so as to cause the degree of localization of the medium to change (e.g., the medium becomes more confined in space or more spread out in space).
FILED Tuesday, November 12, 2019
APPL NO 16/617894
ART UNIT 2881 — Optics
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 19/58 (20130101) Original (OR) Class

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/032 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11243295 Spuler et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Langley Research Center (LaRC)
National Science Foundation (NSF)
Directorate of Geosciences (GEO)
Division of Atmospheric and Geospace Sciences (AGS)
National Center for Atmospheric Research (NCAR)
Federally Funded Research and Development Center (FFRDC)
Operated by University Corporation for Atmospheric Research (UCAR)
APPLICANT(S) University Corporation for Atmospheric Research (Boulder, Colorado);  Montana State University (Bozeman, Montana);  NASA Langley Research Center (Hampton, Virginia)
ASSIGNEE(S) University Corporation for Atmospheric Research (Boulder, Colorado);  Montana State University (Bozeman, Montana);  NASA Langley Research Center (Hampton, Virginia)
INVENTOR(S) Scott M. Spuler (Westminster, Colorado);  Kevin S. Repasky (Bozeman, Montana);  Amin R. Nehrir (Yorktown, Virginia)
ABSTRACT A filter for a micropulse differential absorption LIDAR is provided. The filter comprises an etalon including a free spectral range substantially the same as a difference between a first laser wavelength and a second laser wavelength, the etalon further including a finesse providing substantial background noise suppression and substantially constant transmission of the first laser wavelength and the second laser wavelength over a predetermined range of wavelengths, and a first filter having a first filter bandpass selected to include the first laser wavelength and the second laser wavelength.
FILED Thursday, June 28, 2018
APPL NO 16/022320
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/538 (20130101)
G01N 2021/1795 (20130101)
G01N 2021/4709 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/484 (20130101)
G01S 7/4812 (20130101)
G01S 7/4814 (20130101) Original (OR) Class
G01S 7/4816 (20130101)
G01S 17/18 (20200101)
G01S 17/95 (20130101)

Technologies for Adaptation to Climate Change
Y02A 90/10 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11243419 Cardenas et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) University of Rochester (Rochester, New York)
ASSIGNEE(S) University of Rochester (Rochester, New York)
INVENTOR(S) Jaime Cardenas (Rochester, New York);  Yi Zhang (Rochester, New York)
ABSTRACT A deposition method for manufacturing an active electro-optic layer includes providing a substrate or a base layer; and applying an electric field across a silicon nitride layer as it is being deposited on the substrate or the base layer to cause a poling of a deposited layer. Alternative methods for poling an active electro-optic layer and an electro-optical device are also described.
FILED Thursday, October 17, 2019
APPL NO 16/655816
ART UNIT 2883 — Optics
CURRENT CPC
Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 16/50 (20130101)
C23C 16/345 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/035 (20130101) Original (OR) Class
G02F 2202/20 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/0217 (20130101)
H01L 21/02274 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11243559 Taskin et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) Drexel University (Philadelphia, Pennsylvania);  University of South Florida (Tampa, Florida)
ASSIGNEE(S) Drexel University (Philadelphia, Pennsylvania)
INVENTOR(S) Baris Taskin (Philadelphia, Pennsylvania);  Ragh Kuttappa (Philadelphia, Pennsylvania);  Selcuk Kose (Tampa, Florida)
ABSTRACT Modern integrated circuits have an increasing need for various levels of both supply voltage (V) and operating frequency (f) available at fine spatial and temporal granularity. This work introduces a solution that provides a number and quality of locally distributed V/f domains through FOPAC. Opportunistically sharing design resources and features between multi-phase voltage regulators (MPVRs) and resonant rotary clocks (ReRoCs) enabling i) the scalability to hundreds of domains, ii) fast switching times for both voltage and frequency, leading to temporal flexibility, and iii) locally distributed designs, leading to spatial flexibility.
FILED Friday, May 29, 2020
APPL NO 16/887056
ART UNIT 2849 — Optics
CURRENT CPC
Systems for Regulating Electric or Magnetic Variables
G05F 1/10 (20130101)

Electric Digital Data Processing
G06F 1/10 (20130101) Original (OR) Class

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 23/66 (20130101)

Pulse Technique
H03K 3/012 (20130101)
H03K 3/0315 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11243881 Wang et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Rujia Wang (Chicago, Illinois);  Jun Yang (Pittsburgh, Pennsylvania);  YouTao Zhang (Pittsburgh, Pennsylvania)
ABSTRACT An apparatus including (i) a processor including a plurality of main buffer on board (BOB) memory controllers (MCs) and a secure engine, (ii) a plurality of simple BOB MCs, (iii) a secure delegator, and (iv) a plurality of memory modules. The secure delegator coupled to a first main BOB MC and a first simple BOB MC creates a secure channel. A second main BOB MC coupled to a second simple BOB MC creates a non-secure channel. The plurality of main BOB MCs, the secure engine and the secure delegator are provided within a trusted computing base (TCB) of the apparatus and the plurality of simple BOB MCs and the plurality of memory modules are provided outside the TCB. The secure delegator is configured to: (i) secure communication between the first main BOB MC and the secure delegator, and (ii) perform Path ORAM accesses to the plurality of memory modules.
FILED Tuesday, July 30, 2019
APPL NO 16/526108
ART UNIT 2133 — Memory Access and Control
CURRENT CPC
Electric Digital Data Processing
G06F 9/5016 (20130101)
G06F 12/0638 (20130101) Original (OR) Class
G06F 12/0815 (20130101)
G06F 12/1408 (20130101)
G06F 13/1673 (20130101)
G06F 2212/1021 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11244110 Herr et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) BLACKBOILER, INC. (Arlington, Virginia)
ASSIGNEE(S) BLACKBOILER, INC. (Arlington, Virginia)
INVENTOR(S) Jonathan Herr (Washington, District of Columbia);  Daniel Edward Simonson (Arlington, Virginia);  Daniel P. Broderick (Arlington, Virginia)
ABSTRACT A method for suggesting revisions to a document-under-analysis from a seed database, the seed database including a plurality of original texts each respectively associated with one of a plurality of final texts, the method for suggesting revisions including selecting a statement-under-analysis (“SUA”), selecting a first original text of the plurality of original texts, determining a first edit-type classification of the first original text with respect to its associated final text, generating a first similarity score for the first original text based on the first edit-type classification, the first similarity score representing a degree of similarity between the SUA and the first original text, selecting a second original text of the plurality of original texts, determining a second edit-type classification of the second original text with respect to its associated final text, generating a second similarity score for the second original text based on the second edit-type classification, the second similarity score representing a degree of similarity between the SUA and the second original text, selecting a candidate original text from one of the first original text and the second original text, and creating an edited SUA (“ESUA”) by modifying a copy of the first SUA consistent with a first candidate final text associated with the first candidate original text.
FILED Monday, July 13, 2020
APPL NO 16/927324
ART UNIT 2144 — Graphical User Interface and Document Processing
CURRENT CPC
Electric Digital Data Processing
G06F 16/35 (20190101)
G06F 16/36 (20190101)
G06F 16/383 (20190101)
G06F 40/45 (20200101)
G06F 40/131 (20200101)
G06F 40/137 (20200101)
G06F 40/166 (20200101)
G06F 40/169 (20200101)
G06F 40/194 (20200101)
G06F 40/253 (20200101) Original (OR) Class
G06F 40/268 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11244189 Fathi et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Pointivo, Inc. (Atlanta, Georgia)
ASSIGNEE(S) POINTIVO, INC. (Atlanta, Georgia)
INVENTOR(S) Habib Fathi (Atlanta, Georgia);  Miguel M. Serrano (Marietta, Georgia);  Bradden John Gross (Atlanta, Georgia);  Daniel L. Ciprari (Atlanta, Georgia)
ABSTRACT Examples of various method and systems are provided for information extraction from scene information. 2D image information can be generated from 2D images of the scene that are overlapping at least part of one or more object(s). The 2D image information can be combined with 3D information about the scene incorporating at least part of the object(s) to generate projective geometry information. Clustered 3D information associated with the object(s) can be generated by partitioning and grouping 3D data points present in the 3D information. The clustered 3D information can be used to provide, e.g., measurement information, dimensions, geometric information, and/or topological information about the object(s). Segmented 2D information can also be generated from the 2D image information. Validated 2D and 3D information can be produced by cross-referencing between the projective geometry information, clustered 3D information, and/or segmented 2D image information, and used to label the object(s) in the scene.
FILED Friday, March 13, 2020
APPL NO 16/818814
ART UNIT 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00201 (20130101)
G06K 9/00208 (20130101)
G06K 9/342 (20130101) Original (OR) Class
G06K 9/00664 (20130101)
G06K 9/6218 (20130101)
G06K 2209/40 (20130101)

Image Data Processing or Generation, in General
G06T 7/55 (20170101)
G06T 17/00 (20130101)
G06T 2207/10028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11244309 Bentov et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Cornell University (Ithaca, New York)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) Iddo Bentov (Ithaca, New York);  Ari Juels (New York, New York);  Fan Zhang (Ithaca, New York);  Philip Daian (New York, New York);  Lorenz Breidenbach (Zurich, Switzerland)
ABSTRACT An apparatus in an illustrative embodiment comprises a processing platform that includes one or more processing devices each comprising a processor coupled to a memory. The processing platform is configured to communicate over at least one network with one or more additional sets of processing devices associated with at least a first blockchain-based cryptocurrency system. Each of at least a subset of the one or more processing devices of the processing platform comprises a trusted execution environment, such as a secure enclave. The processing platform is further configured to release from the trusted execution environment of a given one of the one or more processing devices of the processing platform a first blockchain transaction on the first blockchain-based cryptocurrency system, and to condition release of a second blockchain transaction relating to the first blockchain transaction on receipt of at least a specified threshold amount of evidence of confirmation of the first blockchain transaction on the first blockchain-based cryptocurrency system.
FILED Wednesday, November 21, 2018
APPL NO 16/198223
ART UNIT 3685 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC
Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 20/027 (20130101)
G06Q 20/065 (20130101)
G06Q 20/389 (20130101)
G06Q 20/405 (20130101)
G06Q 20/38215 (20130101) Original (OR) Class
G06Q 2220/00 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/0897 (20130101)
H04L 2209/38 (20130101)
H04L 2209/56 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 11241752 Goeke et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS)
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Ronald S. Goeke (Los Ranchos, New Mexico);  Charles A. Walker (Albuquerque, New Mexico);  Juan A. Romero (Bayfield, Colorado)
ABSTRACT Nanometers thick conformal coatings deposited by atomic-layer deposition (ALD) onto the metal surface of an active braze joint modifies the surface chemistry to eliminate excess braze filler metal flow. Unlike other means used to prevent braze filler metal runout, the thin ALD coating does not hinder next assembly processes, does not require post-braze cleaning, and does not alter the base material mechanical properties.
FILED Friday, May 10, 2019
APPL NO 16/409087
ART UNIT 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 1/20 (20130101) Original (OR) Class
B23K 2103/52 (20180801)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 16/403 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11241932 Wang et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) Evelyn N Wang (Cambridge, Massachusetts);  Hyunho Kim (Cambridge, Massachusetts);  Xiansen Li (Lexington, Kentucky);  Shankar Narayan (Chestnut Hill, Massachusetts);  Sameer R. Rao (Cambridge, Massachusetts);  Ari Samuel Umans (Cambridge, Massachusetts);  Sungwoo Yang (Cambridge, Massachusetts)
ABSTRACT An adsorption system can be used as part of a climate control system in a vehicle or in any other space requiring heating or cooling. The adsorbent system can include an enclosure, a plurality of layers arranged in a stack inside the enclosure, and a vapor channel inside the enclosure.
FILED Monday, December 24, 2018
APPL NO 16/231865
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Arrangements of Heating, Cooling, Ventilating or Other Air-treating Devices Specially Adapted for Passenger or Goods Spaces of Vehicles
B60H 1/22 (20130101)
B60H 1/00278 (20130101)
B60H 1/00392 (20130101)
B60H 1/00492 (20130101) Original (OR) Class
B60H 1/3201 (20130101)
B60H 1/3202 (20130101)
B60H 1/32014 (20190501)

Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems
F25B 17/08 (20130101)
F25B 37/00 (20130101)
F25B 2315/007 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242314 Zhou et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Dong Zhou (St. Louis, Missouri);  Wenhua Chu (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Dong Zhou (St. Louis, Missouri);  Wenhua Chu (St. Louis, Missouri)
ABSTRACT The present disclosure relates to the methods for the preparation of reactive [F-18]fluoride in a form of [F-18]sulfonyl fluoride suitable for efficient radiolabeling without an azeotropic evaporation step by the use of anion exchange resin and sulfonyl chloride, and its applications in the manufacturing of PET radiopharmaceuticals.
FILED Wednesday, January 11, 2017
APPL NO 15/403954
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
General Methods of Organic Chemistry; Apparatus Therefor
C07B 59/001 (20130101)
C07B 59/002 (20130101)
C07B 59/005 (20130101)
C07B 2200/05 (20130101)

Acyclic or Carbocyclic Compounds
C07C 45/63 (20130101)
C07C 45/63 (20130101)
C07C 47/55 (20130101)
C07C 67/307 (20130101)
C07C 67/307 (20130101)
C07C 69/76 (20130101)
C07C 247/04 (20130101)
C07C 303/22 (20130101)
C07C 303/22 (20130101)
C07C 303/22 (20130101)
C07C 303/22 (20130101)
C07C 309/86 (20130101)
C07C 309/87 (20130101)
C07C 309/89 (20130101)
C07C 315/04 (20130101) Original (OR) Class

Heterocyclic Compounds
C07D 207/09 (20130101)
C07D 213/52 (20130101)
C07D 213/71 (20130101)
C07D 233/91 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 3/02 (20130101)
C07H 19/06 (20130101)

Steroids
C07J 1/007 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242432 Coates et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) CORNELL UNIVERSITY (Ithaca, New York)
ASSIGNEE(S) CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S) Geoffrey W. Coates (Lansing, New York);  Kristina M. Hugar (Ithaca, New York)
ABSTRACT The invention provides: imidazole and imidazolium compounds of formulas (I) and (II):
polymers containing a plurality of imidazolium-containing repeating units of formula (III′):
and membranes and devices comprising the polymers. Also provided are methods of making the inventive compounds and polymers.
FILED Thursday, April 14, 2016
APPL NO 15/566595
ART UNIT 1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Separation
B01D 71/44 (20130101)
B01D 71/62 (20130101)

Heterocyclic Compounds
C07D 233/58 (20130101)
C07D 233/60 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 8/30 (20130101)
C08F 8/30 (20130101)
C08F 12/26 (20130101)
C08F 26/06 (20130101)
C08F 126/06 (20130101)
C08F 210/14 (20130101)
C08F 210/14 (20130101)
C08F 212/14 (20130101)
C08F 212/36 (20130101)
C08F 214/16 (20130101)
C08F 214/16 (20130101)
C08F 226/06 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 61/02 (20130101)
C08G 61/04 (20130101) Original (OR) Class
C08G 61/06 (20130101)
C08G 61/08 (20130101)
C08G 2261/148 (20130101)
C08G 2261/149 (20130101)
C08G 2261/418 (20130101)
C08G 2261/516 (20130101)
C08G 2261/724 (20130101)
C08G 2261/1424 (20130101)
C08G 2261/3322 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 5/2231 (20130101)
C08J 2323/18 (20130101)
C08J 2323/36 (20130101)

Compositions of Macromolecular Compounds
C08L 25/18 (20130101)
C08L 71/02 (20130101)
C08L 2203/20 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 8/1023 (20130101)
H01M 50/411 (20210101)
H01M 2300/0082 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242544 Donohue et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Timothy James Donohue (Middleton, Wisconsin);  Matthew Scarborough (Madison, Wisconsin);  Daniel Noguera (Madison, Wisconsin)
ABSTRACT Microbiome compositions and uses thereof. The microbiome compositions include a set of microbes. The sets of microbes contain members of Lactobacillaceae, Eubacteriaceae, Lachnospiraceae, and Coriobacteriaceae. The number of individual physical microbes in the set constitutes a certain percentage of the total number of individual physical microbes in the microbiome composition. The microbiome compositions can be used for producing medium-chain fatty acids from organic substrates through anaerobic fermentation in a medium. The medium can include lignocellulosic stillage.
FILED Thursday, June 06, 2019
APPL NO 16/433639
ART UNIT 1699 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/205 (20210501)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/6409 (20130101) Original (OR) Class
C12P 2203/00 (20130101)

Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms
C12R 2001/225 (20210501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242587 Shyam et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB)
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee);  FCA US LLC (Auburn Hills, Michigan);  NEMAK USA, Inc. (Dickson, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee);  FCA US LLC (Auburn Hills, Michigan);  Nemak USA, Inc. (Dickson, Tennessee)
INVENTOR(S) Amit Shyam (Knoxville, Tennessee);  James A. Haynes (Knoxville, Tennessee);  Adrian S. Sabau (Knoxville, Tennessee);  Dongwon Shin (Knoxville, Tennessee);  Yukinori Yamamoto (Knoxville, Tennessee);  Christopher R. Glaspie (Rochester Hills, Michigan);  Jose A. Gonzalez-Villarreal (Monterrey, Mexico);  Seyed Mirmiran (Auburn Hills, Michigan);  Andres F. Rodriguez-Jasso (Garcia, Mexico)
ABSTRACT The present disclosure concerns embodiments of aluminum alloy compositions exhibiting superior microstructural stability and strength at high temperatures. The disclosed aluminum alloy compositions comprise particular combinations of components that contribute the ability of the alloys to exhibit improved microstructural stability and hot tearing resistance as compared to conventional alloys. Also disclosed herein are embodiments of methods of making and using the alloys.
FILED Friday, May 12, 2017
APPL NO 15/594434
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Casting of Metals; Casting of Other Substances by the Same Processes or Devices
B22D 21/007 (20130101)

Alloys
C22C 1/06 (20130101)
C22C 1/026 (20130101)
C22C 21/12 (20130101)
C22C 21/14 (20130101)
C22C 21/16 (20130101)
C22C 21/18 (20130101)

Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys
C22F 1/057 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242756 Zhang et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FE)
National Energy Technology Laboratory (NETL)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) James Zhang (Simpsonville, South Carolina);  John McConnell Delvaux (Fountain Inn, South Carolina)
ABSTRACT A coating is applied to a base material. The coating comprises a viscoelastic layer having a surface in which cavities are formed; and a constraint layer. The viscoelastic layer is disposed on the base material, and the constraint layer is disposed on, and partially bonded, at an interface, to the viscoelastic layer over the surface in which the cavities are formed. The cavities are filled with particles configured for vibration and frictional interaction at the partially bonded interface between the partially bonded viscoelastic layer and the constraint layer. A turbine blade having an airfoil with the subject coating is also provided.
FILED Monday, May 04, 2020
APPL NO 16/865999
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 9/041 (20130101)
B32B 2307/51 (20130101)
B32B 2603/00 (20130101)

Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/16 (20130101) Original (OR) Class
F01D 5/225 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2240/307 (20130101)
F05D 2260/96 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242843 Anderson et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) 247Solar Inc. (Great Falls, Virginia)
ASSIGNEE(S) 247Solar Inc. (Great Falls, Virginia)
INVENTOR(S) Bruce N. Anderson (Great Falls, Virginia);  William Dean Treece (La Mesa, California);  Dan Brown (Lebanon, New Hampshire);  Florian Bennhold (Osnabruk, Germany);  Christoph Hilgert (Odenthal, Germany)
ABSTRACT Inventive concentrated solar power systems using solar receivers, and related devices and methods, are generally described. Low pressure solar receivers are provided that function to convert solar radiation energy to thermal energy of a working fluid, e.g., a working fluid of a power generation or thermal storage system. In some embodiments, low pressure solar receivers are provided herein that are useful in conjunction with gas turbine based power generation systems.
FILED Thursday, March 21, 2019
APPL NO 16/361074
ART UNIT 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 1/04 (20130101)
F02C 1/08 (20130101)

Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for
F03G 6/06 (20130101) Original (OR) Class
F03G 6/064 (20130101)

Solar Heat Collectors; Solar Heat Systems
F24S 10/40 (20180501)
F24S 10/80 (20180501)
F24S 20/20 (20180501)
F24S 23/79 (20180501)
F24S 70/12 (20180501)
F24S 80/20 (20180501)

Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 19/04 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/40 (20130101)
Y02E 10/44 (20130101)
Y02E 10/46 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11243276 Khitun
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Alexander Khitun (Long Beach, California)
ABSTRACT A magnetic field detector and associated methods are shown. One example of a magnetic field detector uses spin wave interference to detect information about an external magnetic field.
FILED Thursday, September 05, 2019
APPL NO 16/562171
ART UNIT 2867 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/1284 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11243315 Taleyarkhan
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB)
APPLICANT(S) Rusi P Taleyarkhan (Lafayette, Indiana)
ASSIGNEE(S) Rusi P. Taleyarkhan (Lafayette, Indiana)
INVENTOR(S) Rusi P Taleyarkhan (Lafayette, Indiana)
ABSTRACT Systems and methods for neutron detection using tensioned metastable fluid detectors, using multi-atom spectroscopy approach.
FILED Thursday, January 30, 2020
APPL NO 16/776512
ART UNIT 2884 — Optics
CURRENT CPC
Measurement of Nuclear or X-radiation
G01T 3/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11243884 Mashimo et al.
FUNDED BY
Department of Energy (DOE)
Exascale Computing Project (ECP)
PathForward Project (PATHFORWARD)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS)
APPLICANT(S) Advanced Micro Devices, Inc. (Santa Clara, California)
ASSIGNEE(S) Advanced Micro Devices, Inc. (Santa Clara, California)
INVENTOR(S) Susumu Mashimo (Boxborough, Massachusetts);  John Kalamatianos (Boxborough, Massachusetts)
ABSTRACT A method of prefetching target data includes, in response to detecting a lock-prefixed instruction for execution in a processor, determining a predicted target memory location for the lock-prefixed instruction based on control flow information associating the lock-prefixed instruction with the predicted target memory location. Target data is prefetched from the predicted target memory location to a cache coupled with the processor, and after completion of the prefetching, the lock-prefixed instruction is executed in the processor using the prefetched target data.
FILED Tuesday, November 13, 2018
APPL NO 16/190111
ART UNIT 2138 — Memory Access and Control
CURRENT CPC
Electric Digital Data Processing
G06F 12/0862 (20130101) Original (OR) Class
G06F 2212/27 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11245103 Mikhaylik et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Sion Power Corporation (Tucson, Arizona)
ASSIGNEE(S) Sion Power Corporation (Tucson, Arizona)
INVENTOR(S) Yuriy V. Mikhaylik (Tucson, Arizona);  Michael G. Laramie (Tucson, Arizona);  John Joseph Christopher Kopera (Vail, Arizona)
ABSTRACT An electrode structure and its method of manufacture are disclosed. The disclosed electrode structures may be manufactured by depositing a first release layer on a first carrier substrate. A first protective layer may be deposited on a surface of the first release layer and a first electroactive material layer may then be deposited on the first protective layer. Subsequently, the first carrier substrate may be delaminated from the first release layer. The first release layer may then be removed from the first protective layer by dissolution in an electrolyte. The first protective layer may have a low mean peak to valley surface roughness and/or may be thin. In some embodiments, an interface between the first protective layer and the first electroactive material layer has a low mean peak to valley surface roughness. In some embodiments, a thickness of the first protective layer is greater than a mean peak to valley roughness of the first release layer. In some embodiments, an adhesive strength between the first release layer and the first protective layer is greater than an adhesive strength between the first release layer and the first carrier substrate.
FILED Friday, March 29, 2019
APPL NO 16/369027
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/13 (20130101)
H01M 4/131 (20130101)
H01M 4/139 (20130101)
H01M 4/0402 (20130101) Original (OR) Class
H01M 4/0407 (20130101)
H01M 4/0423 (20130101)
H01M 4/0428 (20130101)
H01M 4/1391 (20130101)
H01M 10/052 (20130101)
H01M 10/058 (20130101)
H01M 10/0565 (20130101)
H01M 50/461 (20210101)
H01M 2300/0085 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11245111 Yang et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
ASSIGNEE(S) University of Southern California (Los Angeles, California)
INVENTOR(S) Bo Yang (Los Angeles, California);  G. K. Surya Prakash (Hacienda Heights, California);  Robert Aniszfeld (Los Angeles, California);  Sri R. Narayan (Arcadia, California);  Lena Hoober-Burkhardt (Los Angeles, California);  Sankarganesh Krishnamoorthy (Los Angeles, California);  Advaith Murali (Los Angeles, California);  Archith Nirmalchandar (Los Angeles, California)
ABSTRACT A quinone derivative with a high redox potential that does not undergo Michael addition or proto-desulfonation. This molecule addresses the key issues faced with the positive side material of an aqueous all-organic flow battery. This new molecule is 2,5-dihydroxy-4,6-dimethylbenzene-1,3-disulfonic acid (or the disulfonate salt thereof). This quinone derivative offers good solubility, electrochemical reversibility, and robustness to charge/discharge cycling. Quinones with reduced crossover are also provided.
FILED Tuesday, October 16, 2018
APPL NO 16/161647
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 303/08 (20130101)
C07C 303/08 (20130101)
C07C 309/42 (20130101)
C07C 309/42 (20130101)
C07C 309/43 (20130101)
C07C 309/44 (20130101)
C07C 2603/24 (20170501)
C07C 2603/50 (20170501)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/60 (20130101)
H01M 4/368 (20130101) Original (OR) Class
H01M 8/08 (20130101)
H01M 8/188 (20130101)
H01M 2004/028 (20130101)
H01M 2008/1095 (20130101)
H01M 2300/0002 (20130101)
H01M 2300/0082 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11245114 Amine et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO)
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Khalil Amine (Oak Brook, Illinois);  Ali Abouimrane (Bolingbrook, Illinois)
ABSTRACT A secondary battery including a cathode having a primary cathode active material and an alkaline source material selected from the group consisting of Na2O, Na2O2, Na2S, NaF, NaCl, NaBr, Li2O, Li2O2, Li2S, LiF, LiCl, LiBr, Na2O, Na2O2, Na2S, NaF, NaCl, and a mixture of any two or more thereof; an anode having an anode active material; an electrolyte; and a separator.
FILED Thursday, January 19, 2017
APPL NO 15/410125
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/485 (20130101)
H01M 4/505 (20130101)
H01M 4/525 (20130101) Original (OR) Class
H01M 4/5825 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11245330 Giuliano et al.
FUNDED BY
Department of Defense (DOD)
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) David M. Giuliano (Cambridge, Massachusetts);  David J. Perreault (Cambridge, Massachusetts);  Robert C. N. Pilawa-Podgurski (Cambridge, Massachusetts)
ABSTRACT A converter circuit and related technique for providing high power density power conversion includes a reconfigurable switched capacitor transformation stage coupled to a magnetic converter (or regulation) stage. The circuits and techniques achieve high performance over a wide input voltage range or a wide output voltage range. The converter can be used, for example, to power logic devices in portable battery operated devices.
FILED Monday, June 29, 2020
APPL NO 16/915051
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 1/007 (20210501)
H02M 3/07 (20130101)
H02M 3/155 (20130101)
H02M 3/158 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 11241833 Gandhiraman et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Universities Space Research Association (Mountain View, California)
ASSIGNEE(S) UNIVERSITIES SPACE RESEARCH ASSOCIATION (Columbia, Maryland)
INVENTOR(S) Ramprasad Gandhiraman (Sunnyvale, California);  Meyya Meyyappan (Pacifica, California);  Jessica E. Koehne (Portola Valley, California)
ABSTRACT A device and method for printing 3D articles including electronic and functional elements including 3D printer and a plasma jet printer based on a dielectric barrier atmospheric pressure plasma jet system in which both printing and in-situ treatment and post-deposition treatment can be carried out to tailor the materials characteristics. Plasma jet printer comprising of electrodes in the nozzle/print head for applying electric field and generating atmospheric plasma that could be used for non-gravity based highly directional printing in any direction. Integration of dielectric barrier plasma printer and plasma treatment jets with the 3D printer increases the capability of embedding high performance electronics in a 3D printed structure aiding in additive manufacturing of functional devices. Ability to use a range of materials for print head assembly including micro machined silicon increases the resolution of the plasma jet printer to sub-micron level.
FILED Thursday, March 09, 2017
APPL NO 15/454920
ART UNIT 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 3/16 (20130101)
B22F 10/00 (20210101)
B22F 10/10 (20210101)
B22F 12/00 (20210101)
B22F 12/00 (20210101)
B22F 2202/13 (20130101)
B22F 2202/13 (20130101)
B22F 2999/00 (20130101)
B22F 2999/00 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/106 (20170801)
B29C 64/188 (20170801)
B29C 64/321 (20170801) Original (OR) Class

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 30/00 (20141201)
B33Y 50/02 (20141201)
B33Y 70/00 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242134 Nguyen et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as Represented by the Administrator of the NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as Represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) Nhan Thanh Nguyen (Santa Clara, California);  Eric Bi-Wen Ting (Los Altos, California)
ABSTRACT Processes for real-time drag optimization control for aeroelastic wing structures are disclosed. Adaptive reconfiguration of aircraft control surfaces by an online real-time drag optimization control approach to reduce or minimize drag may reduce the amount of fuel that is consumed by the aircraft during flight. The input data may be obtained from sensor information pertaining to the wing deflection and aircraft state information. The optimization approach may compute an optimal solution of the distributed flight control surface deflections that are integrated in a flight path angle flight control system.
FILED Tuesday, May 22, 2018
APPL NO 15/986794
ART UNIT 3666 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Aeroplanes; Helicopters
B64C 9/06 (20130101)
B64C 13/18 (20130101) Original (OR) Class

Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for
B64F 5/60 (20170101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242844 Woodruff et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) CU Aerospace, LLC (Champaign, Illinois)
ASSIGNEE(S) CU Aerospace, LLC (Champagne, Illinois)
INVENTOR(S) Curtis Woodruff (Savoy, Illinois);  Darren King (Champaign, Illinois);  Rodney Burton (Champaign, Illinois);  David L. Carroll (Champaign, Illinois)
ABSTRACT A Fiber-fed Pulsed Plasma Thruster (FPPT) utilizes a motor to feed PTFE fiber to its discharge region, enabling high PPT propellant throughput and variable exposed fuel area. A highly parallel ceramic capacitor bank lowers system specific mass. Impulse bits (I-bits) from 0.057-0.241 mN-s have been measured on a thrust stand with a specific impulse (Isp) of 900-2400 s, representing an enhancement from state-of-the-art PPT technology. A 1 U (10 cm×10 cm×10 cm, or 1 liter) volume FPPT thruster package will provide 2900-7700 N-s total impulse, enabling 0.6-1.6 km/s delta-V for a 5 kg CubeSat. A 1 U design variation with 590 g propellant enables as much as ˜10,000 N-s and a delta-V of 2 km/s for a 5 kg CubeSat. Increasing the form factor to 2U increases propellant mass to 1.4 kg and delta-V to 10.7 km/s for an 8 kg CubeSat.
FILED Thursday, June 13, 2019
APPL NO 16/439755
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Cosmonautics; Vehicles or Equipment Therefor
B64G 1/405 (20130101)

Producing a Reactive Propulsive Thrust, Not Otherwise Provided for
F03H 1/0012 (20130101)
F03H 1/0031 (20130101)
F03H 1/0043 (20130101)
F03H 1/0087 (20130101) Original (OR) Class

Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams
H05H 1/14 (20130101)
H05H 1/54 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11243159 Palinski et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S)
INVENTOR(S) Timothy J. Palinski (Cleveland, Ohio);  Gary W. Hunter (Cleveland, Ohio);  John Zhang (Cleveland, Ohio)
ABSTRACT A tunable colorimetric sensor/optical filter is based on a lithography-free, asymmetric Fabry-Perot cavity. The sensor has a thin-film structure formed by a lossy, porous nanoplasmonic top film deposited on an actively tunable spacer middle layer, and a reflective base layer (either a metal or semiconductor). The structure is fabricated using wafer-scale PVD processes, and the middle layer responds to the presence of a stimulus in the local environment, by expanding in thickness resulting in a shift in resonance wavelength and thus an obvious change in color of the sensor, which color change is detectable by the naked-eye. Such layered geometries exhibit vibrant, macroscopic structural coloration owing to the broadband optical absorption of the top film, enabling the change in spacer thickness to be transduced visually, circumventing the need for sophisticated optical equipment for signal readout to observe the presence of the environmental stimulus.
FILED Thursday, February 06, 2020
APPL NO 16/783712
ART UNIT 2886 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/29 (20130101)
G01N 21/272 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11243188 Pourmand et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Human Genome Research Institute (NHGRI)
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Nader Pourmand (San Mateo, California);  Boaz Vilozny (Santa Cruz, California);  Paolo Actis (London, United Kingdom);  R. Adam Seger (Santa Cruz, California)
ABSTRACT Disclosed are methods and devices for detection of ion migration and binding, utilizing a nanopipette adapted for use in an electrochemical sensing circuit. The nanopipette may be functionalized on its interior bore with metal chelators for binding and sensing metal ions or other specific binding molecules such as boronic acid for binding and sensing glucose. Such a functionalized nanopipette is comprised in an electrical sensor that detects when the nanopipette selectively and reversibly binds ions or small molecules. Also disclosed is a nanoreactor, comprising a nanopipette, for controlling precipitation in aqueous solutions by voltage-directed ion migration, wherein ions may be directed out of the interior bore by a repulsing charge in the bore.
FILED Friday, May 24, 2019
APPL NO 16/422735
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/021 (20130101)
B01L 3/50273 (20130101)
B01L 2300/0896 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 35/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/3277 (20130101)
G01N 27/44791 (20130101) Original (OR) Class
G01N 33/48721 (20130101)

Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM]
G01Q 60/44 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11243295 Spuler et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Langley Research Center (LaRC)
National Science Foundation (NSF)
Directorate of Geosciences (GEO)
Division of Atmospheric and Geospace Sciences (AGS)
National Center for Atmospheric Research (NCAR)
Federally Funded Research and Development Center (FFRDC)
Operated by University Corporation for Atmospheric Research (UCAR)
APPLICANT(S) University Corporation for Atmospheric Research (Boulder, Colorado);  Montana State University (Bozeman, Montana);  NASA Langley Research Center (Hampton, Virginia)
ASSIGNEE(S) University Corporation for Atmospheric Research (Boulder, Colorado);  Montana State University (Bozeman, Montana);  NASA Langley Research Center (Hampton, Virginia)
INVENTOR(S) Scott M. Spuler (Westminster, Colorado);  Kevin S. Repasky (Bozeman, Montana);  Amin R. Nehrir (Yorktown, Virginia)
ABSTRACT A filter for a micropulse differential absorption LIDAR is provided. The filter comprises an etalon including a free spectral range substantially the same as a difference between a first laser wavelength and a second laser wavelength, the etalon further including a finesse providing substantial background noise suppression and substantially constant transmission of the first laser wavelength and the second laser wavelength over a predetermined range of wavelengths, and a first filter having a first filter bandpass selected to include the first laser wavelength and the second laser wavelength.
FILED Thursday, June 28, 2018
APPL NO 16/022320
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/538 (20130101)
G01N 2021/1795 (20130101)
G01N 2021/4709 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/484 (20130101)
G01S 7/4812 (20130101)
G01S 7/4814 (20130101) Original (OR) Class
G01S 7/4816 (20130101)
G01S 17/18 (20200101)
G01S 17/95 (20130101)

Technologies for Adaptation to Climate Change
Y02A 90/10 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11243561 Mautner et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Johnson Space Center (JSC)
APPLICANT(S) THE CHARLES STARK DRAPER LABORATORY, INC. (Cambridge, Massachusetts)
ASSIGNEE(S) THE CHARLES STARK DRAPER LABORATORY, INC. (Cambridge, Massachusetts)
INVENTOR(S) Eric Karl Mautner (Hudson, Massachusetts);  Brianna Klingensmith (Arlington, Massachusetts)
ABSTRACT The present disclosure relates to systems and methods to maintain clock synchronization of multiple computers, or computer systems, through the exchange of communication messages that include clock and/or timing information.
FILED Thursday, July 25, 2019
APPL NO 16/522163
ART UNIT 2187 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 1/12 (20130101)
G06F 1/14 (20130101) Original (OR) Class
G06F 13/122 (20130101)

Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses
H03L 7/0814 (20130101)
H03L 7/0991 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 7/0025 (20130101)
H04L 7/0037 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11244775 Han et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Ames Research Center (ARC)
APPLICANT(S) Universities Space Research Association (Columbia, Maryland)
ASSIGNEE(S) UNIVERSITIES SPACE RESEARCH ASSOCIATION (Columbia, Maryland)
INVENTOR(S) Jin-Woo Han (Mountain View, California);  Meyya Meyyappan (San Jose, California);  Dong-Il Moon (Mountain View, California)
ABSTRACT An all-printed physically unclonable function based on a single-walled carbon nanotube network. The network may be a mixture of semiconducting and metallic nanotubes randomly tangled with each other through the printing process. The unique distribution of carbon nanotubes in a network can be used for authentication, and this feature can be a secret key for a high level hardware security. The carbon nanotube network does not require any advanced purification process, alignment of nanotubes, high-resolution lithography and patterning. Rather, the intrinsic randomness of carbon nanotubes is leveraged to provide the unclonable aspect.
FILED Wednesday, December 11, 2019
APPL NO 16/710760
ART UNIT 2833 — Electrical Circuits and Systems
CURRENT CPC
Resistors
H01C 1/14 (20130101)
H01C 1/034 (20130101)
H01C 7/006 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 11241671 Petruska et al.
FUNDED BY
National Science Foundation (NSF)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) Melissa A. Petruska (Newtown, Connecticut);  Trevor E. James (Plantsville, Connecticut);  James D. Carruthers (Reno, Nevada);  Peter C. Van Buskirk (Newtown, Connecticut);  Jeffrey F. Roeder (Brookfield, Connecticut)
ASSIGNEE(S) Sonata Scientific LLC (Danbury, Connecticut)
INVENTOR(S) Melissa A. Petruska (Newtown, Connecticut);  Trevor E. James (Plantsville, Connecticut);  James D. Carruthers (Reno, Nevada);  Peter C. Van Buskirk (Newtown, Connecticut);  Jeffrey F. Roeder (Brookfield, Connecticut)
ABSTRACT Monolithic composite photocatalysts for fluid purification, chemical transformations, and surface sterilization are disclosed. The monolithic composite photocatalysts comprise a photoactive nanocrystal component and a non-photoactive porous support. Photocatalytic fluid purification systems that contact an impurity-containing fluid with the subject monolithic composite photocatalysts are also disclosed.
FILED Tuesday, November 12, 2019
APPL NO 16/680495
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 2/10 (20130101)
A61L 2/16 (20130101)
A61L 2/084 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 21/063 (20130101) Original (OR) Class
B01J 35/004 (20130101)
B01J 35/04 (20130101)
B01J 35/006 (20130101)
B01J 35/08 (20130101)
B01J 35/023 (20130101)
B01J 35/1014 (20130101)
B01J 35/1019 (20130101)
B01J 35/1023 (20130101)
B01J 35/1061 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 35/00 (20130101)
B82Y 40/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11243976 Beckham et al.
FUNDED BY
Department of Homeland Security (DHS)
Science and Technology Directorate (DHS-S&T)
Department of Agriculture (USDA)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S)
INVENTOR(S) Tammy Beckham (Manhattan, Kansas);  Matthew Coats (Washington, District of Columbia);  John Korslund (Riverdale, Maryland);  Michelle Colby (Washington, District of Columbia);  James Wall (College Station, Texas);  Keith Biggers (College Station, Texas);  Melissa Berquist (College Station, Texas);  Austin Riddle (College Station, Texas);  Paul Bilnoski (College Station, Texas);  Derek Overby (Covington, Louisiana);  Graham Booker (College Station, Texas);  Lindsey Holmstrom (Manhattan, Kansas)
ABSTRACT A system and computerized method for monitoring and analyzing animal related data. In one embodiment, the system includes a processor and memory operable to identify a parameter related to animal management for species in a biological environment, aggregate animal related data from different sources about the parameter of the species, identify a baseline for the parameter, correlate the animal related data against the baseline to obtain correlated data, and analyze said correlated data to assess said animal management.
FILED Friday, March 23, 2018
APPL NO 15/933910
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 11/008 (20130101)
A01K 29/005 (20130101)

Electric Digital Data Processing
G06F 3/04847 (20130101)
G06F 16/26 (20190101) Original (OR) Class
G06F 16/29 (20190101)
G06F 40/106 (20200101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/10 (20130101)
G06Q 50/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 11243976 Beckham et al.
FUNDED BY
Department of Homeland Security (DHS)
Science and Technology Directorate (DHS-S&T)
Department of Agriculture (USDA)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S)
INVENTOR(S) Tammy Beckham (Manhattan, Kansas);  Matthew Coats (Washington, District of Columbia);  John Korslund (Riverdale, Maryland);  Michelle Colby (Washington, District of Columbia);  James Wall (College Station, Texas);  Keith Biggers (College Station, Texas);  Melissa Berquist (College Station, Texas);  Austin Riddle (College Station, Texas);  Paul Bilnoski (College Station, Texas);  Derek Overby (Covington, Louisiana);  Graham Booker (College Station, Texas);  Lindsey Holmstrom (Manhattan, Kansas)
ABSTRACT A system and computerized method for monitoring and analyzing animal related data. In one embodiment, the system includes a processor and memory operable to identify a parameter related to animal management for species in a biological environment, aggregate animal related data from different sources about the parameter of the species, identify a baseline for the parameter, correlate the animal related data against the baseline to obtain correlated data, and analyze said correlated data to assess said animal management.
FILED Friday, March 23, 2018
APPL NO 15/933910
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 11/008 (20130101)
A01K 29/005 (20130101)

Electric Digital Data Processing
G06F 3/04847 (20130101)
G06F 16/26 (20190101) Original (OR) Class
G06F 16/29 (20190101)
G06F 40/106 (20200101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/10 (20130101)
G06Q 50/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11244527 Hastings et al.
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
INVENTOR(S) William Hastings (Alexandria, Virginia);  Sherif Ahmed (Starnberg, Germany);  James Gilkeson (Alexandria, Virginia);  Douglas MacIvor (Arlington, Virginia);  Luke Olsen (Alexandria, Virginia)
ABSTRACT Various embodiments of the present invention are directed toward systems and methods relating to security screening. For example, a screening system includes a chamber configured to accommodate a user to be screened, and a chamber scanner. The chamber scanner is configured to scan the user to identify whether the user is carrying an undivested item that needs to be divested. The chamber is configured to release the user to proceed from the chamber to a secure area, upon confirmation that no undivested items are to be divested.
FILED Friday, April 03, 2020
APPL NO 16/839763
ART UNIT 2631 — Digital Communications
CURRENT CPC
Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags
G01V 5/0041 (20130101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 50/265 (20130101)

Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere
G07C 9/28 (20200101) Original (OR) Class

Signalling or Calling Systems; Order Telegraphs; Alarm Systems
G08B 21/182 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 11241189 Smiley et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
Non-Profit Organization (NPO)
The Cleveland Clinic Foundation
APPLICANT(S) THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio);  The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia);  The MetroHealth System (Cleveland, Ohio)
ASSIGNEE(S) THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio);  THE METROHEALTH SYSTEM (Cleveland, Ohio);  THE U.S. GOV'T AS REPRESENTED BY THE DEPT OF VETERANS AFFAIRS (Washington, District of Columbia)
INVENTOR(S) Aref Smiley (Cleveland, Ohio);  Dennis Bourbeau (Cleveland Hts., Ohio);  Margot S. Damaser (Cleveland Hts., Ohio);  Steve Majerus (University Hts., Ohio);  Massarat Zutshi (Cleveland Hts., Ohio);  Ian Mcadams (Cleveland Hts., Ohio)
ABSTRACT A sensing device can be placed within the colon to study bowel function. The sensing device can include a flexible printed circuit board that includes at least one senor configured to record data related to bowel activity from a patient's colon; and a wireless transmitter configured to send the data from the patient's colon to an external device. The sensing device can also include at least one mucosal clip configured to fix the sensor board to a wall of the patient's colon for a measurement period. The flexible printed circuit board and/or the at least one mucosal clip are configured to be passed from the patient's colon after the measurement period through normal defecation.
FILED Wednesday, July 17, 2019
APPL NO 16/514982
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/07 (20130101)
A61B 5/0022 (20130101)
A61B 5/0031 (20130101)
A61B 5/4255 (20130101) Original (OR) Class

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/36007 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11242339 Mallampalli et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Office of Research and Development (DVAORD)
Veterans Health Administration (VHA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute on Aging (NIA)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Rama K. Mallampalli (Sewickley, Pennsylvania);  Beibei Chen (Sewickley, Pennsylvania);  Charleen T. Chu (Wexford, Pennsylvania);  Yuan Liu (Sewickley, Pennsylvania)
ABSTRACT A method for treating a neurodegenerative disease or an inflammatory disorder in a subject, comprising administering to the subject in need thereof, a compound, or a pharmaceutically acceptable salt thereof, of formula II:
wherein each of R3-R7 is independently H, halogen, optionally-substituted alkyl, amino, alkoxy or hydroxy; R8 is an optionally-substituted heterocycloalkyl; and a is 0 to 3.
FILED Monday, June 25, 2018
APPL NO 16/624843
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/517 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/16 (20180101)
A61P 25/28 (20180101)

Heterocyclic Compounds
C07D 405/12 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Non-Profit Organization (NPO) 

US 11241189 Smiley et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
Non-Profit Organization (NPO)
The Cleveland Clinic Foundation
APPLICANT(S) THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio);  The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia);  The MetroHealth System (Cleveland, Ohio)
ASSIGNEE(S) THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio);  THE METROHEALTH SYSTEM (Cleveland, Ohio);  THE U.S. GOV'T AS REPRESENTED BY THE DEPT OF VETERANS AFFAIRS (Washington, District of Columbia)
INVENTOR(S) Aref Smiley (Cleveland, Ohio);  Dennis Bourbeau (Cleveland Hts., Ohio);  Margot S. Damaser (Cleveland Hts., Ohio);  Steve Majerus (University Hts., Ohio);  Massarat Zutshi (Cleveland Hts., Ohio);  Ian Mcadams (Cleveland Hts., Ohio)
ABSTRACT A sensing device can be placed within the colon to study bowel function. The sensing device can include a flexible printed circuit board that includes at least one senor configured to record data related to bowel activity from a patient's colon; and a wireless transmitter configured to send the data from the patient's colon to an external device. The sensing device can also include at least one mucosal clip configured to fix the sensor board to a wall of the patient's colon for a measurement period. The flexible printed circuit board and/or the at least one mucosal clip are configured to be passed from the patient's colon after the measurement period through normal defecation.
FILED Wednesday, July 17, 2019
APPL NO 16/514982
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/07 (20130101)
A61B 5/0022 (20130101)
A61B 5/0031 (20130101)
A61B 5/4255 (20130101) Original (OR) Class

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/36007 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 11244274 Klausner et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Peter Klausner (Washington, District of Columbia);  Robert E. Dixon, Jr. (Haymarket, Virginia)
ABSTRACT Systems described herein for controlling, requesting, and coordinating the creation and generation of labels can be a label broker, providing a centralized location for storing label information created by various entities, and managing the requests for generation of physical labels coming from various sources and entities.
FILED Monday, April 30, 2018
APPL NO 15/967141
ART UNIT 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/083 (20130101) Original (OR) Class
G06Q 50/28 (20130101)

Ticket-issuing Apparatus; Fare-registering Apparatus; Franking Apparatus
G07B 17/00016 (20130101)
G07B 17/00314 (20130101)
G07B 17/00508 (20130101)
G07B 2017/00064 (20130101)
G07B 2017/00161 (20130101)
G07B 2017/00258 (20130101)
G07B 2017/00588 (20130101)

Coin-freed or Like Apparatus
G07F 17/42 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 11242761 Behling et al.
FUNDED BY
APPLICANT(S) United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S) Raytheon Technologies Corporation (Farmington, Connecticut)
INVENTOR(S) Weston Behling (Norwalk, Connecticut);  Michael C. Weber (Niantic, Connecticut);  William B. McLean (East Hampton, Connecticut);  William S. Pratt (West Hartford, Connecticut);  Joon Ha (Glastonbury, Connecticut)
ABSTRACT A rotor disk assembly for a gas turbine engine includes a rotor disk that defines an axis, the rotor disk comprising a slot within a rim of the disk and a spacer within the slot, the spacer having a clearance feature sized to permit rotation of a rotor blade from an insertion position to an installed position.
FILED Tuesday, February 18, 2020
APPL NO 16/793307
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/32 (20130101)
F01D 5/303 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2260/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11243955 Ackermann et al.
FUNDED BY
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Christopher F. Ackermann (Fairfax, Virginia);  Charles E. Beller (Baltimore, Maryland);  Stephen A. Boxwell (Columbus, Ohio);  Edward G. Katz (Washington, District of Columbia);  Kristen M. Summers (Takoma Park, Maryland)
ABSTRACT The present invention may receive the question, a plurality of the candidate answers, and a plurality of documents associated with the plurality of candidate answers in the natural language. Then the present invention may tokenize the question, the plurality of the candidate answers, and the plurality of the documents into a corresponding n-gram sequence. The present invention may map n-gram elements from the tokenized question to the n-gram elements of the plurality of the tokenized candidate answers and the plurality of the tokenized documents using the latent token representation technique. The present invention may score the plurality of tokenized candidate answers based on the latent token representation technique. Then, the present invention may determine the precise answer based on the plurality of scored candidate answers.
FILED Wednesday, November 29, 2017
APPL NO 15/825824
ART UNIT 2162 — Data Bases & File Management
CURRENT CPC
Electric Digital Data Processing
G06F 16/93 (20190101)
G06F 16/243 (20190101)
G06F 16/3329 (20190101)
G06F 16/24564 (20190101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, February 08, 2022.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2021/details-patents-20210427.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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