FedInvent™ Patents
Patent Details for Tuesday, May 10, 2022
This page was updated on Tuesday, May 10, 2022 at 07:58 PM GMT
Department of Health and Human Services (HHS)
| US 11324398 | Miller et al. |
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| FUNDED BY |
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| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Donald Thomas Miller (Bloomington, Indiana); Zhuolin Liu (North Potomac, Maryland); Kazuhiro Suzuki (Bloomington, Indiana); Furu Zhang (Bloomington, Indiana) |
| ABSTRACT | A method is provided for observing structure and function of individual cells in a living human eye, comprising: using an adaptive optics optical coherence tomography (AO-OCT) system to image a volume of a retinal patch including numerous cells of different types, as for example, ganglion cells; using 3D subcellular image registration to correct for eye motion, including digitally dissecting the imaged volume; and using organelle motility inside the cell to increase cell contrast and to measure cell temporal dynamics. |
| FILED | Thursday, July 25, 2019 |
| APPL NO | 16/522183 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/13 (20130101) A61B 3/14 (20130101) A61B 3/0025 (20130101) Original (OR) Class A61B 3/102 (20130101) A61B 3/1225 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11324430 | Sternberger |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Wayne I. Sternberger (Highland, Maryland) |
| ABSTRACT | Example apparatuses, systems, and methods for detecting a muscle tissue ischemia event are provided. An example apparatus may include an electromyography (EMG) sensor applied to a patient to detect electrical activity in the muscle tissue. The apparatus may also include processing circuitry in communication with the EMG sensor and configured to receive EMG signals from the EMG sensor and detect characteristics within the EMG signals indicating oxygen depletion within the muscle tissue of the patient. The characteristics may include a signal power level of the EMG signals increasing by at least a threshold value at a select frequency or with respect to a select band of frequencies. The processing circuitry may be further configured to trigger an output, in response to detecting the characteristics, indicating that the oxygen depletion in the muscle tissue is indicative of an ischemia event. |
| FILED | Wednesday, November 14, 2018 |
| APPL NO | 16/190733 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/004 (20130101) A61B 5/296 (20210101) Original (OR) Class A61B 5/316 (20210101) A61B 5/389 (20210101) A61B 5/447 (20130101) A61B 5/14551 (20130101) A61B 2562/0271 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11324555 | Maiorano et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Anthony Maiorano (Waltham, Massachusetts); Jeffrey C. Cerier (Franklin, Massachusetts) |
| ABSTRACT | An instrument port includes a port body, a bulb disposed at the distal end of the port body, a base body disposed at the proximal end of the port body, a hollow cylindrical body mechanically coupled to the base body, and a plurality of connecting rods disposed parallel to the port body. Each connecting rod includes a distal rod portion that is mechanically coupled to a respective distal-facing exterior surface of a bulb flange and a proximal rod portion that is mechanically coupled to a respective proximal-facing surface of the base body. A spring applies a spring force against the port body to press the port body into the bulb to mechanically secure the bulb to the base body. |
| FILED | Friday, March 09, 2018 |
| APPL NO | 15/916667 |
| ART UNIT | 3795 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/0008 (20130101) A61B 1/018 (20130101) A61B 1/00096 (20130101) A61B 1/00137 (20130101) A61B 1/00142 (20130101) A61B 17/3417 (20130101) A61B 17/3421 (20130101) A61B 34/20 (20160201) Original (OR) Class A61B 90/30 (20160201) A61B 90/361 (20160201) A61B 2018/00982 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11324697 | Puder et al. |
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| APPLICANT(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Mark Puder (Medfield, Massachusetts); Kathleen Marie Gura (Norfolk, Massachusetts) |
| ABSTRACT | Described herein are emulsion compositions comprising fish oil and medium-chain triglycerides (MCT) and/or omega-3 fatty acids and medium-chain triglycerides (MCT). In some embodiments, the compositions further comprise, e.g., alpha-tocopherol, or one or more fatty acids. Further provided herein are methods of using the compositions, e.g., to provide nutrion, e.g., parenteral nutrition to a subject and/or to treat or prevent certain conditions described herein. |
| FILED | Friday, August 10, 2018 |
| APPL NO | 16/634194 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/11 (20160801) A23L 33/15 (20160801) A23L 33/40 (20160801) A23L 33/115 (20160801) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/107 (20130101) Original (OR) Class A61K 31/23 (20130101) A61K 31/202 (20130101) A61K 31/355 (20130101) A61K 35/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11324723 | Johnson |
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| FUNDED BY |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Bankole A. Johnson (Charlottesville, Virginia) |
| ABSTRACT | Compositions and methods are provided that are useful for diagnosing, treating, and monitoring alcohol dependence and disorders, susceptibility to alcohol dependence disorders, as well as drug related dependence and disorders. The methods include treating patients with an antagonist of the serotonin receptor 5-HT3 for such disorders, wherein the patient's serotonin transporter gene SLC6A4 is known to have particular genotypes. |
| FILED | Thursday, February 06, 2020 |
| APPL NO | 16/784051 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4178 (20130101) Original (OR) Class A61K 31/7048 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 1/6888 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) C12Q 2600/172 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11324725 | Hoon et al. |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Mark A. Hoon (Kensington, Maryland); Hans Juergen Solinski (Pr. Oldendorf, Germany); James Inglese (Bethesda, Maryland); Patricia Dranchak (Gaithersburg, Maryland) |
| ABSTRACT | Pharmaceutical compositions comprising a molecular inhibitor of Npr1 are disclosed. Also disclosed are methods of treating, reducing, or preventing acute and/or chronic pruritus in a mammal comprising administering a pharmaceutical composition comprising a molecular inhibitor of Npr1. |
| FILED | Friday, November 02, 2018 |
| APPL NO | 16/761047 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) A61K 31/395 (20130101) A61K 31/422 (20130101) Original (OR) Class A61K 31/497 (20130101) A61K 31/506 (20130101) A61K 31/4439 (20130101) A61K 31/4545 (20130101) A61K 31/5513 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11324731 | Natarajan et al. |
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| APPLICANT(S) | CITY OF HOPE (Duarte, California) |
| ASSIGNEE(S) | CITY OF HOPE (Duarte, California) |
| INVENTOR(S) | Rama Natarajan (Hacienda Heights, California); Feng Miao (Alhambra, California); Nagarajan Vaidehi (Arcadia, California); Supriyo Bhattacharya (Monrovia, California); Adrien Beau Larsen (Duarte, California) |
| ABSTRACT | Disclosed herein, inter alia, are compounds and methods for inhibiting the thioredoxin-thioredoxin-interacting-protein (TXNIP-TRX) complex. |
| FILED | Friday, September 13, 2019 |
| APPL NO | 16/570802 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) Original (OR) Class A61K 31/496 (20130101) A61K 31/4035 (20130101) A61K 31/4439 (20130101) A61K 31/5377 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11324742 | Prisinzano et al. |
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| APPLICANT(S) | Victoria Link Ltd. (Wellington, New Zealand); University of Kansas (Lawrence, Kansas) |
| ASSIGNEE(S) | Victoria Link Ltd. (Wellington, New Zealand); University of Kansas (Lawrence, Kansas) |
| INVENTOR(S) | Thomas Edward Prisinzano (Lawrence, Kansas); Bronwyn Maree Kivell (Wellington, New Zealand); Anne Camille La Flamme (Wellington, New Zealand) |
| ABSTRACT | The present invention relates generally to methods of using nalfurafine for treating and/or preventing demyelinating disease in a subject, and in particular for treating and/or preventing multiple sclerosis (MS). Also disclosed is nalfurafine for use in treating and/or preventing MS as well as pharmaceutical compositions and unit dosage forms comprising nalfurafine for use for treating and/or preventing demyelinating disease in a subject, and in particular for treating and/or preventing MS. |
| FILED | Thursday, July 23, 2020 |
| APPL NO | 16/936975 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/485 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11324748 | Chilian et al. |
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| APPLICANT(S) | NORTHEAST OHIO MEDICAL UNIVERSITY (Rootstown, Ohio) |
| ASSIGNEE(S) | NORTHEAST OHIO MEDICAL UNIVERSITY (Rootstown, Ohio) |
| INVENTOR(S) | William M. Chilian (Atwater, Ohio); Vahagn Ohanyan (Hudson, Ohio); Liya Yin (Hudson, Ohio) |
| ABSTRACT | A method for treating or preventing heart failure involving blockage of small blood vessels is described. The method involves administering to a subject in need thereof a therapeutically effective amount of a vasodilator. |
| FILED | Monday, April 23, 2018 |
| APPL NO | 16/606451 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 31/353 (20130101) A61K 31/519 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/08 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11324765 | Morrow et al. |
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| APPLICANT(S) | Children's Hospital Medical Center (Cincinnati, Ohio); The General Hospital Corporation (Boston, Massachusetts); Instituto Nacional de Ciencias Medicas Y Nutricion (Mexico City, Mexico) |
| ASSIGNEE(S) | Children's Hospital Medical Center (Cincinnati, Ohio); The General Hospital Corporation (Boston, Massachusetts); Instituto Nacional de Ciencias Medicas Y Nutricion (Mexico City, Mexico) |
| INVENTOR(S) | Ardythe L. Morrow (Cincinnatti, Ohio); David S. Newburg (Newtonville, Massachusetts); Guillermo M. Ruiz-Palacios (Mexico City, Mexico) |
| ABSTRACT | A method of inhibiting inflammation with milk oligosaccharides or glycoconjugates containing the oligosaccharides. |
| FILED | Friday, May 28, 2021 |
| APPL NO | 17/333614 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/40 (20160801) Preparations for Medical, Dental, or Toilet Purposes A61K 31/702 (20130101) A61K 31/7016 (20130101) Original (OR) Class A61K 35/20 (20130101) A61K 47/50 (20170801) A61K 47/61 (20170801) A61K 47/62 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11324773 | Schoenfisch et al. |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Mark H. Schoenfisch (Chapel Hill, North Carolina); Katelyn Reighard (Chapel Hill, North Carolina) |
| ABSTRACT | Provided herein are compounds, compositions, and methods for modifying mucus, including modifying mucus using nitric oxide-releasing biopolymers (e.g., NO-releasing chitosan oligosaccharides). In some embodiments, a compound, composition, and/or method of the present invention modifies one or more properties of mucus to increase mucus clearance in a subject and/or prevents the growth or kills one or more pathogens present in mucus of a subject. |
| FILED | Tuesday, April 10, 2018 |
| APPL NO | 16/500755 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0065 (20130101) A61K 31/785 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11324774 | O'Connor et al. |
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| APPLICANT(S) | Augusta University Research Institute, Inc. (Augusta, Georgia) |
| ASSIGNEE(S) | Augusta University Research Institute, Inc. (Augusta, Georgia) |
| INVENTOR(S) | Paul O'Connor (Martinez, Georgia); Ryan Harris (Augusta, Georgia) |
| ABSTRACT | Compositions of alkaline salts and metabolic acid inducers and methods of use thereof are provided. The disclosed compositions may be used for stimulating vagal nerve efferent pathways, treating or preventing an inflammatory response or an autoimmune disorder, inhibiting or reducing one or more inflammatory M1 macrophages and/or one or more inflammatory neutrophils in the blood, promoting polarization of macrophages from a pro-inflammatory M1 state to an anti-inflammatory M2 state, and treating or preventing cardiovascular disease or metabolic disorders. |
| FILED | Wednesday, January 02, 2019 |
| APPL NO | 16/237885 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/0056 (20130101) A61K 9/0095 (20130101) A61K 31/198 (20130101) A61K 33/00 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/04 (20180101) A61P 3/10 (20180101) A61P 9/10 (20180101) A61P 9/12 (20180101) A61P 29/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11324779 | Rossen et al. |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Ninna S. Rossen (Brooklyn, New York); Samuel K. Sia (New York, New York); Brian M. Gillette (Bronx, New York) |
| ABSTRACT | Spheroid microtissues that can mimic native tissue-like structure and function, spheroid production methods that are high-throughput, suitable for efficient production, maintainable over long-term culture, and/or offer repeatable control over size distribution. Spheroids that have blood vessels, including spheroids with functional, blood-perfused vascular networks upon injection in vivo. Dissolvable hydrogel microwell arrays for high throughput parallel formation of spheroids in a single pipetting step and easy retrieval for downstream applications. A method to produce prevascularized microtissues in sufficient numbers to form a macrotissue in vivo for therapeutic purposes. This method is based on sacrificial release of dissolvable microwell templates, a novel and scalable strategy which enables gentle harvesting of microtissues with control over size and composition. The method forms microtissues containing endothelial cells and mesenchymal stem cells, which are co-cultured under dynamic conditions and self-organize into blood-vessel units. |
| FILED | Friday, September 01, 2017 |
| APPL NO | 15/694152 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/5063 (20130101) A61K 35/28 (20130101) A61K 35/44 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0691 (20130101) C12N 5/0697 (20130101) C12N 2501/02 (20130101) C12N 2501/33 (20130101) C12N 2501/39 (20130101) C12N 2501/81 (20130101) C12N 2501/115 (20130101) C12N 2501/165 (20130101) C12N 2501/385 (20130101) C12N 2501/395 (20130101) C12N 2502/28 (20130101) C12N 2502/1352 (20130101) C12N 2502/1358 (20130101) C12N 2539/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11324814 | Wu et al. |
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| APPLICANT(S) | Protein Potential, LLC (Rockville, Maryland) |
| ASSIGNEE(S) | Protein Potential, LLC (Rockville, Maryland) |
| INVENTOR(S) | Yun Wu (Rockville, Maryland); Dennis J. Kopecko (Silver Spring, Maryland); B. Kim Lee Sim (Gaithersburg, Maryland); Stephen L. Hoffman (Gaithersburg, Maryland) |
| ABSTRACT | Disclosed is the attenuated Salmonella typhi vaccine Ty21a utilized as a vector for Shigella and/or enterotoxogenic E. coli genes stably integrated in the Ty21a chromosome. These genes include a heterologous Shigella sonnei O-antigen biosynthetic gene region that comprises the wzz gene and expresses Shigella sonnei form 1 O-antigen, as well as a heterologous acid resistance biosynthetic gene system comprising a YbaS gene, which enables increased stability of the Ty21a vector at pH 2.5 relative to Ty21a without the integrated acid resistance biosynthetic gene system. |
| FILED | Wednesday, June 10, 2020 |
| APPL NO | 16/897999 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/116 (20130101) A61K 39/0275 (20130101) A61K 39/0283 (20130101) Original (OR) Class A61K 2039/70 (20130101) A61K 2039/522 (20130101) A61K 2039/523 (20130101) A61K 2039/543 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11324816 | Galarza et al. |
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| APPLICANT(S) | TechnoVax, Inc. (Elmsford, New York) |
| ASSIGNEE(S) | TechnoVax, Inc. (Elmsford, New York) |
| INVENTOR(S) | Jose M. Galarza (Elmsford, New York); Velasco Cimica (Elmsford, New York); Hélène Boigard (Chanceaux sur Choisille, France) |
| ABSTRACT | Described herein are virus-like particles (VLPs) that display on their surfaces antigenic paramyxovirus (e.g., RSV and/or MPV) proteins. Also described are methods of making and using these VLPs. |
| FILED | Monday, August 29, 2016 |
| APPL NO | 15/755897 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2760/18323 (20130101) C12N 2760/18334 (20130101) C12N 2760/18523 (20130101) C12N 2760/18534 (20130101) C12N 2760/18571 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11324817 | Gale, Jr. et al. |
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| APPLICANT(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| INVENTOR(S) | Michael J. Gale, Jr. (Seattle, Washington); Gretja Schnell (Seattle, Washington); Yueh-Ming Loo (Seattle, Washington) |
| ABSTRACT | Compositions and methods are provided that enable activation of innate immune responses through RIG-I like receptor signaling. The compositions and methods incorporate synthetic nucleic acid pathogen associated molecular patterns (PAMPs) that comprise elements initially characterized in, and derived from, the hepatitis C virus genome. |
| FILED | Monday, October 07, 2019 |
| APPL NO | 16/595288 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 39/12 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 45/06 (20130101) A61K 2039/57 (20130101) A61K 2039/555 (20130101) A61K 2039/55561 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/117 (20130101) C12N 2310/17 (20130101) C12N 2770/24134 (20130101) C12N 2770/24232 (20130101) C12N 2770/24234 (20130101) C12N 2770/24271 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11324819 | Clark et al. |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington); Abacus Bioscience, Inc. (Sammamish, Washington) |
| INVENTOR(S) | Edward Clark (Seattle, Washington); Deborah L. Fuller (Seattle, Washington); Che-Leung Law (Seattle, Washington); Amanda Mak (Seattle, Washington) |
| ABSTRACT | Provided herein are compositions of CD1280 binding proteins and a Hepatitis B virus core antigen (HBcAg) and/or a Hepatitis B virus E antigen (HBeAg), or antigenic fragments or mutants thereof, attached to the CD180 binding protein, and methods for using the compositions to treat or limit the development of hepatitis-B virus (HBV)-related disorders. |
| FILED | Tuesday, November 22, 2016 |
| APPL NO | 16/088386 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) A61K 39/292 (20130101) Original (OR) Class A61K 39/001129 (20180801) Peptides C07K 16/2896 (20130101) C07K 2317/56 (20130101) C07K 2317/524 (20130101) C07K 2317/526 (20130101) C07K 2317/622 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2730/10134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11324821 | Martin et al. |
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| APPLICANT(S) | ADJUVANCE TECHNOLOGIES, INC. (Lincoln, Nebraska) |
| ASSIGNEE(S) | ADJUVANCE TECHNOLOGIES, INC. (Lincoln, Nebraska) |
| INVENTOR(S) | J Tyler Martin (Roca, Nebraska); Jeffrey Gardner (New York, New York) |
| ABSTRACT | The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases and cancers. |
| FILED | Monday, October 15, 2018 |
| APPL NO | 16/649892 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 39/00 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 2039/55577 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11324824 | Shemesh et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Or A. Shemesh (Somerville, Massachusetts); Changyang Linghu (Cambridge, Massachusetts); Edward Boyden (Chestnut Hill, Massachusetts) |
| ABSTRACT | The invention, in some aspects, relates to polypeptide molecules and their encoding nucleic acid molecules and use of such molecules to target opsins to the soma of cells in which they are expressed. Compositions of the invention may be delivered to cells and subjects and used in methods to modulate electrical activity of cells in which they are expressed, and for treatment of diseases and conditions in subjects. |
| FILED | Saturday, June 03, 2017 |
| APPL NO | 16/306627 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/17 (20130101) A61K 41/0057 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/06 (20130101) A61N 5/062 (20130101) Peptides C07K 14/405 (20130101) C07K 14/705 (20130101) C07K 14/4716 (20130101) C07K 14/70571 (20130101) C07K 2319/01 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) C12N 13/00 (20130101) C12N 15/86 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/566 (20130101) G01N 33/5058 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11324840 | Zabow et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by Secretary, Dept. of Health and Human Services (Bethesda, Maryland); The United States of America, as Represented by the Secretary of Commerce (Washington, District of Columbia) |
| ASSIGNEE(S) | THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland); THE USA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia) |
| INVENTOR(S) | Gary Zabow (Washington, District of Columbia); Stephen Dodd (Bethesda, Maryland); Alan Koretsky (Bethesda, Maryland); John Moreland (Washington, District of Columbia) |
| ABSTRACT | The present invention relates to a magnetic resonance structure with a cavity or a reserved space that provides contrast and the additional ability to frequency-shift the spectral signature of the NMR-susceptible nuclei such as water protons by a discrete and controllable characteristic frequency shift that is unique to each MRS design. The invention also relates to nearly uniform solid magnetic resonance T2* contrast agents that have a significantly higher magnetic moment compared to similarly-sized existing MRI contrast agents. |
| FILED | Monday, March 04, 2019 |
| APPL NO | 16/291731 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/0515 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/18 (20130101) A61K 49/1818 (20130101) A61K 49/1821 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 30/00 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/281 (20130101) G01R 33/563 (20130101) G01R 33/5601 (20130101) G01R 33/5635 (20130101) G01R 33/56325 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11324858 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Christopher S. Chen (Newton, Massachusetts); Jan D. Baranski (Philadelphia, Pennsylvania); Ritika Chaturvedi (Philadelphia, Pennsylvania); Michael T. Yang (West Windsor, New Jersey); Kelly R. Stevens (Seattle, Washington); Sangeeta N. Bhatia (Lexington, Massachusetts) |
| ABSTRACT | The present disclosure provides patterned biomaterials having organized cords and extracellular matrix embedded in a 3D scaffold. According, the present disclosure provides compositions and applications for patterned biomaterials. Pre-patterning of these biomaterials can lead to enhanced integration of these materials into host organisms, providing a strategy for enhancing the viability of engineered tissues by promoting vascularization. |
| FILED | Friday, March 26, 2021 |
| APPL NO | 17/213423 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/44 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/24 (20130101) A61L 27/40 (20130101) A61L 27/50 (20130101) Original (OR) Class A61L 27/225 (20130101) A61L 27/507 (20130101) A61L 27/3604 (20130101) A61L 27/3804 (20130101) A61L 27/3808 (20130101) A61L 27/3834 (20130101) A61L 27/3839 (20130101) A61L 27/3886 (20130101) A61L 2430/20 (20130101) A61L 2430/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11324974 | Hubbard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Devin Kerry Hubbard (Chapel Hill, North Carolina); Nicole Lewis Wiley (Pittsboro, North Carolina); Ethan John Smith (Garner, North Carolina) |
| ABSTRACT | Face mask devices, systems, and methods of use include a frame that holds a suitable filter material, including a face mask, over the user's face to form a seal and prevent unfiltered air from being inhaled through the nose or mouth of the user without first passing through the filter material. The frame is removably attached over the users face by, for example, adjustable straps. The frame may be adjustable in size to be suitable for use on user's having different facial sizes, shapes, and/or geometries. |
| FILED | Friday, April 16, 2021 |
| APPL NO | 17/232596 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 13/1161 (20130101) Devices, Apparatus or Methods for Life-saving A62B 7/10 (20130101) Original (OR) Class A62B 18/02 (20130101) A62B 18/082 (20130101) A62B 18/084 (20130101) A62B 23/025 (20130101) Separation B01D 39/16 (20130101) B01D 39/083 (20130101) B01D 46/0005 (20130101) B01D 2239/0622 (20130101) B01D 2239/0627 (20130101) B01D 2279/65 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325112 | Matsui et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Research Foundation of the City University of New York (New York, New York) |
| ASSIGNEE(S) | Research Foundation of the City University of New York (New York, New York) |
| INVENTOR(S) | Hiroshi Matsui (Glen Rock, New Jersey); Zengyan Wei (Corona, New York); Justin Fang (New York, New York) |
| ABSTRACT | Nanocages are formed by etching nanocubes. The nanocubes are added to an aqueous system having an amphiphilic lipid dissolved in an organic solvent (e.g. a hydrophobic alcohol) to form reverse micelles. As the water evaporates the micelles shrink as etching of the flat surface of the nanocubes occurs. In this fashion hollow nanocages are produced. In one embodiment, the nanocage is covalently attached to a polymer shell (e.g. a dextran shell). |
| FILED | Monday, May 18, 2020 |
| APPL NO | 16/876206 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/1824 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/44 (20130101) B01J 23/52 (20130101) B01J 31/06 (20130101) B01J 31/28 (20130101) Original (OR) Class B01J 35/0013 (20130101) B01J 2231/4211 (20130101) B01J 2531/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325119 | NG Pitti et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Carlos Francisco NG Pitti (Jamaica Plain, Massachusetts); Ulri Nicole Lee (Seattle, Washington); Richard Novak (Boston, Massachusetts); Olivier Yves Frederic Henry (Brookline, Massachusetts); Remco Van Erp (Sint Anthonis, Netherlands); Donald E. Ingber (Boston, Massachusetts) |
| ABSTRACT | A fluidic device includes a fluidic layer, a capture material, and an electronics layer, the fluidic layer includes a main channel and a pair of sample channels fluidly coupled to the main channel. The pair of sample channels is configured to receive and introduce a sample material into the device. The sample material includes an analyte. The capture material is positioned in a portion of the main channel that is spaced from the pair of sample channels. The capture material has a three-dimensional matrix of receptors therein configured to bond with the analyte. The capture material has a length that is associated with a dynamic range of the fluidic device and a cross-sectional area that is associated with a sensitivity of the fluidic device. The electronics layer includes electrodes configured to measure an electrical resistance through a portion of the capture material. |
| FILED | Wednesday, March 14, 2018 |
| APPL NO | 16/494230 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) Original (OR) Class B01L 3/502715 (20130101) B01L 2300/069 (20130101) B01L 2300/0645 (20130101) B01L 2300/0867 (20130101) B01L 2300/0896 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/08 (20130101) G01N 33/48707 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325898 | Brabander et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Jef De Brabander (Dallas, Texas); Qiren Liang (Dallas, Texas); Beth Levine (Dallas, Texas); Wei-Chung Chiang (Dallas, Texas) |
| ABSTRACT | Small molecule disruptors of Beclin-1/Bcl-2 protein-protein interactions induce autophagy and hence are useful for treating a variety of indications where stimulation of autophagy is therapeutically useful, including cancer, infection immunity, neurodegeneration, longevity. |
| FILED | Friday, December 04, 2020 |
| APPL NO | 17/112980 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 231/06 (20130101) C07D 231/12 (20130101) C07D 401/04 (20130101) C07D 403/04 (20130101) C07D 405/04 (20130101) Original (OR) Class C07D 405/06 (20130101) C07D 405/12 (20130101) C07D 405/14 (20130101) C07D 409/04 (20130101) C07D 413/04 (20130101) C07D 413/10 (20130101) C07D 417/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325904 | John et al. |
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| FUNDED BY |
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| APPLICANT(S) | Varghese John (San Francisco, California); Dale E. Bredesen (Novato, California) |
| ASSIGNEE(S) | BUCK INSTITUTE FOR RESEARCH ON AGING (Novato, California) |
| INVENTOR(S) | Varghese John (San Francisco, California); Dale E. Bredesen (Novato, California) |
| ABSTRACT | In various embodiments, compositions and methods are provided for treatment and/or prevention of amyloidogenic diseases. In certain embodiments, the methods entail administering an effective amount of a tropinol ester to a subject in need thereof for prophylactic or therapeutic effect. The methods are particularly useful for prophylactic and therapeutic treatment of Alzheimer's disease. In certain embodiments, methods of reducing the risk, lessening the severity, or delaying the progression or onset of a disease characterized by beta-amyloid deposits in the brain of a mammal are also provided. In certain embodiments, methods of directly or indirectly inhibiting the C-terminal cleavage of APP resulting in the formation of APP-C31 peptide and APPneo (AP-P664) in a mammal are provided. |
| FILED | Wednesday, August 01, 2012 |
| APPL NO | 14/235405 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/439 (20130101) A61K 31/444 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 451/12 (20130101) C07D 453/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325910 | Gray et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Nathanael S. Gray (Boston, Massachusetts); Tinghu Zhang (Brookline, Massachusetts); Nicholas Paul Kwiatkowski (Brookline, Massachusetts) |
| ABSTRACT | The present invention provides novel compounds of Formula (I), (II), or (III), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, prodrugs, and compositions thereof. Also provided are methods and kits involving the inventive compounds or compositions for treating and/or preventing proliferative diseases (e.g., cancers (e.g., leukemia, acute lymphoblastic leukemia, lymphoma, Burkitt's lymphoma, melanoma, multiple myeloma, breast cancer, Ewing's sarcoma, osteosarcoma, brain cancer, ovarian cancer, neuroblastoma, lung cancer, colorectal cancer), benign neoplasms, diseases associated with angiogenesis, inflammatory diseases, autoinflammatory diseases, and autoimmune diseases) in a subject. Treatment of a subject with a proliferative disease using a compound or composition of the invention may inhibit the aberrant activity of a kinase, such as a cyclin-dependent kinase (CDK) (e.g., CDK7, CDK12, or CDK13), and therefore, induce cellular apoptosis and/or inhibit transcription in the subject. |
| FILED | Monday, February 03, 2020 |
| APPL NO | 16/780268 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 43/00 (20180101) Heterocyclic Compounds C07D 473/16 (20130101) Original (OR) Class C07D 473/34 (20130101) C07D 487/04 (20130101) Peptides C07K 14/4738 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325931 | Slusher et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY AS CR v.v.i. (Prague, Czech Republic) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland); Inst of Organic Chem. and Biochemistry AS CR V.V.I (Prague, Czech Republic) |
| INVENTOR(S) | Barbara Slusher (Kingsville, Maryland); Rana Rais (Kingsville, Maryland); Marcela Krecmerova (Prague, Czech Republic); Tomas Tichy (Prague, Czech Republic); Pavel Majer (Sykesville, Maryland); Andrej Jancarik (Koprivnice, Czech Republic) |
| ABSTRACT | Methods and compounds are disclosed for treating a disease or condition by inhibiting PSMA (Prostate Specific Membrane Antigen) using prodrugs of 2-PMPA. |
| FILED | Friday, January 24, 2020 |
| APPL NO | 16/751556 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/3808 (20130101) C07F 9/4006 (20130101) C07F 9/4075 (20130101) C07F 9/4084 (20130101) C07F 9/4087 (20130101) C07F 9/4465 (20130101) C07F 9/65586 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325936 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Xi Chen (Davis, California); An Xiao (Davis, California); Wanqing Li (Davis, California); Xixuan Li (Davis, California); Yanhong Li (Davis, California); Teri Slack (Davis, California) |
| ABSTRACT | New 2-deoxy-2,3-dehydro-sialic acids and 2,7-anhydro-sialic acids, which are useful as sialidase inhibitors, and enzymatic methods for preparing them are disclosed. The methods include forming a reaction mixture comprising a glycoside acceptor, a sialic acid donor, and a sialyltransferase; maintaining the reaction mixture under conditions sufficient to form a sialoside; and contacting the sialoside with a Streptococcus pneumoniae sialidase to form the sialic acid product. Methods for the inhibition and sialidases and the treatment of cancer and infectious diseases are also disclosed. |
| FILED | Friday, April 27, 2018 |
| APPL NO | 16/608640 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7012 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/00 (20130101) C07H 5/04 (20130101) Original (OR) Class C07H 15/207 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/26 (20130101) C12P 19/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325939 | Guo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| ASSIGNEE(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| INVENTOR(S) | Peixuan Guo (Columbus, Ohio); Carlo M. Croce (Columbus, Ohio); Tae Jin Lee (Columbus, Ohio); Farzin Haque (Long Island City, New York); Hui Li (Columbus, Ohio) |
| ABSTRACT | The presently-disclosed subject matter relates to an artificial RNA nanostructure molecule and method to treat brain tumor in a subject. More particularly, the presently disclosed subject matter relates to a RNA nanostructure containing a multiple branched RNA nanoparticle, a brain tumor targeting module, and an effective amount of a therapeutic agent. Further, the presently disclosed subject matter relates to a method of using the RNA nanostructure composition to treat brain tumor in a subject having or at risk of having brain tumor. |
| FILED | Monday, March 09, 2020 |
| APPL NO | 16/813087 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/551 (20170801) A61K 47/6929 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 15/115 (20130101) C12N 2310/14 (20130101) C12N 2310/52 (20130101) C12N 2310/113 (20130101) C12N 2310/3231 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325944 | Aldrich et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Jane V. Aldrich (Gainesville, Florida); Laura E. Hanold (Gainesville, Florida) |
| ABSTRACT | The invention relates to macrocyclic peptides and pharmaceutical compositions thereof. The invention further relates to pharmaceutical compositions for modulating opioid receptor activity. |
| FILED | Friday, June 15, 2018 |
| APPL NO | 16/622749 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 5/126 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325956 | Boye et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Sanford L. Boye (Gainesville, Florida); Shannon E. Boye (Gainesville, Florida); Frank Dyka (Gainesville, Florida); William W. Hauswirth (Gainesville, Florida) |
| ABSTRACT | Disclosed are materials and methods for treating diseases of the mammalian eye, and in particular, Usher syndrome 1B (USH1B). The invention provides AAV-based, dual-vector systems that facilitate the expression of full-length proteins whose coding sequences exceed that of the polynucleotide packaging capacity of an individual AAV vector. In one embodiment, vector systems are provided that include i) a first AAV vector polynucleotide that includes an inverted terminal repeat at each end of the polynucleotide and a suitable promoter followed by a partial coding sequence that encodes an N-terminal portion of a full-length polypeptide; and ii) a second AAV vector polynucleotide that includes an inverted terminal repeat at each end of the polynucleotide and a partial coding sequence that encodes a C-terminal portion of a full-length polypeptide, optionally followed by a polyadenylation (pA) signal sequence. In another embodiment, the vector system includes i) a first AAV vector polynucleotide comprising an inverted terminal repeat at each end, a suitable promoter followed by a partial coding sequence that encodes an N-terminal portion of a full-length polypeptide followed by a splice donor site and intron and ii) a second AAV vector polynucleotide comprising an inverted terminal repeat at each end, followed by an intron and a splice-acceptor site for the intron, followed by a partial coding sequence that encodes a C-terminal portion of a full-length polypeptide, optionally followed by a polyadenylation (pA) signal sequence. The coding sequence or the intron sequence in the first and second AAV vectors preferably includes a sequence region that overlaps. |
| FILED | Friday, February 01, 2019 |
| APPL NO | 16/265864 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0066 (20130101) Peptides C07K 14/47 (20130101) Original (OR) Class C07K 14/4716 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14143 (20130101) C12N 2800/40 (20130101) C12N 2830/50 (20130101) C12N 2840/445 (20130101) C12N 2999/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325962 | Finn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Olivera J. Finn (Pittsburgh, Pennsylvania); Nehad M. Alajez (Riyadh, Saudi Arabia); Jan Schmielau (Lubeck, Germany); Mark D. Alter (Brooklyn, New York) |
| ABSTRACT | The invention provides an isolated nucleic acid encoding a receptor, other than an immunoglobulin, wherein the receptor binds to a MUC1 tumor antigen independently of an major histocompatibility complex (MHC). The invention provides a method of activating a signaling pathway and/or killing a cancer cell using a receptor that is similar to or is a T cell receptor. |
| FILED | Wednesday, March 27, 2019 |
| APPL NO | 16/366885 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/00 (20130101) Peptides C07K 14/7051 (20130101) Original (OR) Class C07K 14/70503 (20130101) C07K 16/2809 (20130101) C07K 16/3092 (20130101) C07K 2317/34 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2799/027 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57492 (20130101) G01N 2333/4725 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325965 | Bok et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); INSTITUTO NACIONAL DE TECNOLOGIA AGROPECUARIA (Buenos Aires, Argentina) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); Instituto Nacional De Technologia Agropecuaria (Buenos Aires, Argentina) |
| INVENTOR(S) | Karin Bok (Bethesda, Maryland); Lorena Laura Garaicoechea (Buenos Aires, Argentina); Viviana Parreno (Buenos Aires, Argentina); Andrea Pamela Aguilar (Buenos Aires, Argentina); Marina Bok (Buenos Aires, Argentina); Lisbeth Kim Green (Olney, Maryland); Stanislav Vladimirovich Sosnovtsev (North Potomac, Maryland) |
| ABSTRACT | Isolated VHH monoclonal antibodies are disclosed that specifically bind to a Norovirus polypeptide. In some embodiments, the Norovirus is a Genogroup I Norovirus or a Genogroup II Norovirus. In other embodiments, the Norovirus is Norwalk or MD2004 virus. In some embodiments, the monoclonal antibodies specifically bind VP1. Also disclosed are compositions including the disclosed antibodies, nucleic acids encoding these antibodies, expression vectors including the nucleic acids, and isolated host cells that express the nucleic acids. The antibodies and compositions disclosed herein can be used for detecting the presence of a Norovirus in a biological sample, or detecting a Norovirus infection. Also disclosed are methods of treating and/or preventing a NoV infection. |
| FILED | Tuesday, April 21, 2020 |
| APPL NO | 16/854703 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/22 (20130101) C07K 2317/24 (20130101) C07K 2317/33 (20130101) C07K 2317/34 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/569 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2770/16011 (20130101) C12N 2770/16034 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325966 | Nussenzweig et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Rockefeller University (New York, New York); California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | The Rockefeller University (New York, New York); California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Michel Nussenzweig (New York, New York); Natalia T. Freund (New York, New York); Pamela J. Bjorkman (La Canada Flintridge, California); Louise Scharf (Porter Ranch, California) |
| ABSTRACT | This invention relates to broadly neutralizing and potent anti-HIV-1 antibodies, kits, and methods of use thereof. |
| FILED | Friday, December 22, 2017 |
| APPL NO | 16/473847 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/21 (20130101) A61K 2039/507 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) Peptides C07K 16/1045 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325973 | Krummel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Matthew Krummel (San Francisco, California); Miranda Broz (San Francisco, California); Denise Wolf (San Francisco, California); Joshua Pollack (San Francisco, California); Mikhail Binnewies (San Francisco, California) |
| ABSTRACT | Provided herein are methods and compositions for enhancing an immune response and/or for the treatment of an immune-related condition in an individual, e.g., cancer, comprising killing, disabling, or depleting non-stimulatory myeloid cells using an antigen binding protein such as an antibody or antigen binding fragment thereof. |
| FILED | Monday, July 01, 2019 |
| APPL NO | 16/459589 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/30 (20130101) C07K 16/243 (20130101) C07K 16/2803 (20130101) Original (OR) Class C07K 16/2818 (20130101) C07K 16/2863 (20130101) C07K 16/3046 (20130101) C07K 16/3053 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0626 (20130101) C12N 5/0639 (20130101) C12N 5/0645 (20130101) C12N 5/0693 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325974 | Diaz et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Luis Diaz (Ellicot City, Maryland); Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Nickolas Papadopoulos (Towson, Maryland); Dung Le (Lutherville, Maryland); Drew M. Pardoll (Brookville, Maryland); Suzanne L. Topalian (Brookville, Maryland) |
| ABSTRACT | Blockade of immune checkpoints such as cytotoxic T-lymphocyte antigen-4 (CTLA-4) and programmed death-1 (PD-1) shows promise in patients with cancer. Inhibitory antibodies directed at these receptors have been shown to break immune tolerance and promote anti-tumor immunity. These agents work particularly well in patients with a certain category of tumor. Such tumors may be particularly susceptible to treatment because of the multitude of neoantigens which they produce. |
| FILED | Tuesday, December 22, 2020 |
| APPL NO | 17/131326 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/55 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/30 (20130101) C07K 16/40 (20130101) C07K 16/2803 (20130101) Original (OR) Class C07K 16/2818 (20130101) C07K 16/2827 (20130101) C07K 2317/00 (20130101) C07K 2317/24 (20130101) C07K 2317/76 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) Enzymes C12Y 113/11052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325978 | Tisdale et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as Represented by the Secretary of the Department of Health and Human (Rockville, Maryland) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| INVENTOR(S) | John Fitzgerald Tisdale (Washington, District of Columbia); Bjorg Gudmundsdottir (Silver Spring, Maryland); Laxminath Tumburu (Bethesda, Maryland) |
| ABSTRACT | The present invention provides new compositions and methods useful for the treatment and potential cure of beta-globinopathies such as sickle cell disease and beta-thalassemia by inhibiting the expression and/or activity of RIOK3. |
| FILED | Wednesday, November 06, 2019 |
| APPL NO | 16/676369 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/14 (20130101) A61K 9/0019 (20130101) A61K 9/20 (20130101) A61K 9/0053 (20130101) A61K 9/4808 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/06 (20180101) Peptides C07K 16/2863 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325987 | Zhang et al. |
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| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Peiming Zhang (Gilbert, Arizona); Xu Wang (Tempe, Arizona); Jong One Im (Tempe, Arizona); Stuart Lindsay (Phoenix, Arizona) |
| ABSTRACT | The present disclosure provides a method for identifying and quantifying sulfated glycosaminoglycans, including for example heparin, by passing a sample through nanopores. The glycosaminoglycans sample is measured in microliter quantities, at nanomolar concentrations with detection of impurities below 0.5%, and a dynamic range over five decades of magnitude with a trained machine learning algorithm. |
| FILED | Wednesday, October 10, 2018 |
| APPL NO | 16/155972 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Polysaccharides; Derivatives Thereof C08B 37/0069 (20130101) C08B 37/0075 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 20/10 (20190101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 40/10 (20190201) G16B 40/20 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326138 | Trinkle et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| ASSIGNEE(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| INVENTOR(S) | Christine Trinkle (Lexington, Kentucky); Ren Xu (Lexington, Kentucky); Soroosh Torabi (Lexington, Kentucky) |
| ABSTRACT | Provided herein is a tissue culture device and a method of forming a tissue culture device. The tissue culture device includes a microfluidic layer including at least one hydrophobic microchannel and a reservoir portion over the at least one hydrophobic microchannel, the reservoir portion including an opening aligned with the at least one hydrophobic microchannel. The method of forming a tissue culture device includes providing a microfluidic layer mold, a reservoir layer mold, and a removable lid mold, filling each of the molds with a device material, curing the device material within the molds, removing the cured device material from the molds to provide a microfluidic layer, a reservoir layer, and a removable lid, and bonding the microfluidic layer to the reservoir layer. A method of culturing tissue with the tissue culture device is also provided herein. |
| FILED | Tuesday, May 01, 2018 |
| APPL NO | 15/968262 |
| ART UNIT | 1799 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) Original (OR) Class C12M 23/20 (20130101) C12M 23/38 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0693 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326157 | Joung et al. |
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| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | J. Keith Joung (Winchester, Massachusetts); Jason Michael Gehrke (Cambridge, Massachusetts) |
| ABSTRACT | Methods and compositions for improving the genome-wide specificities of targeted base editing technologies. |
| FILED | Friday, May 25, 2018 |
| APPL NO | 16/615559 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/435 (20130101) C07K 14/4703 (20130101) C07K 2319/70 (20130101) C07K 2319/80 (20130101) C07K 2319/81 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0647 (20130101) C12N 9/22 (20130101) C12N 9/78 (20130101) Original (OR) Class C12N 15/63 (20130101) C12N 15/90 (20130101) C12N 15/102 (20130101) C12N 2310/20 (20170501) Enzymes C12Y 305/04001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326161 | Church et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | George M. Church (Brookline, Massachusetts); Seth Lawler Shipman (Boston, Massachusetts); Jeffrey D. Macklis (Brookline, Massachusetts); Jeffrey Matthew Nivala (Allston, Massachusetts) |
| ABSTRACT | This invention provides methods of altering a cell including providing the cell with a nucleic acid sequence encoding a Cas1 protein and/or a Cas2 protein of a CRISPR adaptation system, providing the cell with a CRISPR array nucleic acid sequence including a leader sequence and at least one repeat sequence, wherein the cell expresses the Cas1 protein and/or the Cas2 protein and wherein the CRISPR array nucleic acid sequence is within genomic DNA of the cell or on a plasmid. Also provided are methods and systems for nucleic acid storage and in vivo molecular recordings of events into a cell. |
| FILED | Thursday, February 16, 2017 |
| APPL NO | 15/999616 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2310/122 (20130101) Computer Systems Based on Specific Computational Models G06N 3/123 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326167 | Simons et al. |
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| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Michael Simons (Hamden, Connecticut); Pei-Yu Chen (East Haven, Connecticut) |
| ABSTRACT | In some aspects, the invention provides a method of treating atherosclerosis in a subject. The method comprises administering to the subject an agent that increases the activity or level of a let-7 miRNA or an agent that decreases activity or level of a TGFβ signaling polypeptide in an endothelial cell in the subject. In some embodiments, the subject is administered an additional agent comprising a therapeutically effective amount of rapamycin or any derivative thereof. In some embodiments, the agent is a let-7 miRNA. In some other aspects, the invention provides a pharmaceutical composition comprising a let-7 miRNA. In some embodiments, the let-7 miRNA is encapsulated in a nanoparticle formulated for selective delivery to an endothelial cell. |
| FILED | Tuesday, March 21, 2017 |
| APPL NO | 16/086809 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/51 (20130101) A61K 31/436 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1138 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/141 (20130101) C12N 2310/321 (20130101) C12N 2310/321 (20130101) C12N 2310/3521 (20130101) C12N 2320/32 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326215 | Parveen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| INVENTOR(S) | Nikhat Parveen (West Orange, New Jersey); Salvatore A. E. Marras (Roselle Park, New Jersey) |
| ABSTRACT | The present invention provides novel methods of diagnosing and determining treatment strategies for Lyme disease and other tick-borne illnesses. |
| FILED | Monday, November 18, 2019 |
| APPL NO | 16/686460 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Original (OR) Class C12Q 1/6883 (20130101) C12Q 2600/16 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11327076 | Barbero et al. |
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| FUNDED BY |
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| APPLICANT(S) | Meso Scale Technologies, LLC. (Rockville, Maryland) |
| ASSIGNEE(S) | Meso Scale Technologies, LLC. (Rockville, Maryland) |
| INVENTOR(S) | Simone Barbero (Germantown, Maryland); Eli N. Glezer (Del Mar, California); Anu Mathew (North Potomac, Maryland) |
| ABSTRACT | The present invention relates to methods of diagnosing breast cancer in a patient, as well as methods of monitoring the progression of breast cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein. |
| FILED | Thursday, October 11, 2018 |
| APPL NO | 16/157341 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/5377 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/42 (20130101) C12Q 1/485 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57415 (20130101) Original (OR) Class G01N 2333/912 (20130101) G01N 2333/916 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11327130 | Halperin |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Henry R. Halperin (Baltimore, Maryland) |
| ABSTRACT | An embodiment in accordance with the present invention provides an improved electrically conductive transmission line that is radio frequency (RF) safe. The present invention does not include any inductive coupling elements. Instead, multiple coils constructed from twisted pairs of wires are used to block the common mode of the received magnetic resonance (MR) signal that can cause heating, while passing the differential mode that is used for tracking and/or imaging. These twisted pair coils are easily manufactured out of a single length of twisted pair wire, but multiple segments could also be used. The twisted pair coils of the present invention are easier to manufacture than the pre-existing inductive coupling element-based transmission lines, and occupy less overall volume inside a medical device. The individual coils of twisted pairs are tuned to the resonant frequency of the MR scanner by the addition of appropriate capacitors. |
| FILED | Tuesday, May 16, 2017 |
| APPL NO | 16/301033 |
| ART UNIT | 2868 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/287 (20130101) G01R 33/288 (20130101) G01R 33/3685 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11327163 | Palmeri et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Mark Palmeri (Durham, North Carolina); Kathryn R. Nightingale (Durham, North Carolina) |
| ABSTRACT | Methods, systems and computer program products for determining a mechanical parameter for a sample having a target region using constructive shear wave displacement is provided. The method includes generating a first shear wave in the target region at a first excitation position and a second shear wave in the target region at a second excitation position; transmitting tracking pulses in the target region at a tracking position that is between the first and second excitation positions; receiving corresponding echo signals for the tracking pulses at the tracking position in the target region; and determining at least one mechanical parameter of the target region based on at least one parameter of a constructive shear wave displacement from the first and second shear waves simultaneously displacing tissue at the tracking position. |
| FILED | Thursday, April 21, 2016 |
| APPL NO | 16/076379 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/52026 (20130101) G01S 7/52036 (20130101) G01S 7/52042 (20130101) Original (OR) Class G01S 7/52085 (20130101) G01S 15/8915 (20130101) G01S 15/8922 (20130101) G01S 15/8927 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11328185 | Zhou et al. |
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| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Edward H. Zhou (Cupertino, California); Michelle Cua (Pasadena, California) |
| ABSTRACT | A system and method for performing speckle correlation flow cytometry (SCFC). By subtracting out the stationary background when shining light through a sample (e.g., a vessel within a biological tissue), light only scattered by the desired targets (e.g., cells) can be captured and different types of targets (e.g., cells) can be distinguished by the autocorrelation of the speckle pattern. In this way, the targets (e.g., cells) can be classified and counted based on the features of their speckle correlations. The technique can be applied not only for noninvasive, label-free, in vivo CTC counting but also for counting other types of blood cells such as white blood cells or red blood cells. |
| FILED | Monday, July 02, 2018 |
| APPL NO | 16/025864 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1455 (20130101) A61B 5/14535 (20130101) A61B 90/20 (20160201) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1404 (20130101) G01N 15/1429 (20130101) G01N 15/1459 (20130101) G01N 2015/1006 (20130101) G01N 2015/1454 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00127 (20130101) G06K 9/628 (20130101) Original (OR) Class G06K 9/2027 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/246 (20170101) G06T 7/254 (20170101) G06T 2207/10016 (20130101) G06T 2207/30024 (20130101) G06T 2207/30096 (20130101) G06T 2207/30101 (20130101) G06T 2207/30104 (20130101) G06T 2207/30242 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11328391 | Li et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Zhoubo Li (Libertyville, Illinois); Cynthia H. McCollough (Byron, Minnesota); Shuai Leng (Rochester, Minnesota); Lifeng Yu (Byron, Minnesota); Armando Manduca (Rochester, Minnesota) |
| ABSTRACT | System and methods are provided for producing computed tomography (CT) images. In some aspects, a method includes obtaining medical image data sets acquired using the multiple energies of irradiating radiation and analyzing the medical image data sets for spatial and spectral features. The method also includes comparing the spatial and spectral features of the medical image data sets to identify similarities and using the similarities, weighting the medical image data sets to generate images of the subject having reduced noise compared to images of the subject produced from the medical image data sets without weighting. |
| FILED | Monday, May 08, 2017 |
| APPL NO | 16/099332 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/032 (20130101) A61B 6/482 (20130101) A61B 6/5258 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6215 (20130101) Image Data Processing or Generation, in General G06T 5/002 (20130101) Original (OR) Class G06T 5/20 (20130101) G06T 5/50 (20130101) G06T 11/008 (20130101) G06T 2200/04 (20130101) G06T 2207/10081 (20130101) G06T 2207/20021 (20130101) G06T 2207/20024 (20130101) Image or Video Recognition or Understanding G06V 10/759 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11328430 | Zhou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Zongwei Zhou (Tempe, Arizona); Md Mahfuzur Rahman Siddiquee (Tempe, Arizona); Nima Tajbakhsh (Los Angeles, California); Jianming Liang (Scottsdale, Arizona) |
| ABSTRACT | Methods, systems, and media for segmenting images are provided. In some embodiments, the method comprises: generating an aggregate U-Net comprised of a plurality of U-Nets, wherein each U-Net in the plurality of U-Nets has a different depth, wherein each U-Net is comprised of a plurality of nodes Xi,j, wherein i indicates a down-sampling layer the U-Net, and wherein j indicates a convolution layer of the U-Net; training the aggregate U-Net by: for each training sample in a group of training samples, calculating, for each node in the plurality of nodes Xi,j, a feature map xi,j, wherein xi,j is based on a convolution operation performed on a down-sampling of an output from Xi−1,j when j=0, and wherein xi,j is based on a convolution operation performed on an up-sampling operation of an output from Xi+1,j−1 when j>0; and predicting a segmentation of a test image using the trained aggregate U-Net. |
| FILED | Thursday, May 28, 2020 |
| APPL NO | 16/885579 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/143 (20170101) Original (OR) Class G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11328813 | Gordon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF DEFENSE (Washington, District of Columbia); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia) |
| INVENTOR(S) | Chad Gordon (Cockeysville, Maryland); Mehran Armand (Fulton, Maryland); Ryan Murphy (Columbia, Maryland); Gerald Grant (Goshen, Kentucky); Peter Liacouras (North Potomac, Maryland); Kevin Wolfe (Lutherville, Maryland); Ehsan Basafa (Baltimore, Maryland) |
| ABSTRACT | A method for computer-assisted planning of a transplant surgery is provided. The method includes obtaining a computer-readable representation of a donor and recipient skeletal fragment; determining surgical cutting planes on the computer-readable representation of the donor skeletal fragment from which a portion of the donor skeletal fragment from the computer-readable representation of the donor skeletal fragment will be harvested; determining virtual cutting guides; performing a virtual osteotomy to separate the portion of the donor skeletal fragment from the computer-readable representation of the donor skeletal fragment from a remainder portion of the donor skeletal fragment based on a position of the virtual cutting guides that are attached to the computer-readable representation of the donor skeletal fragment; positioning the donor skeletal fragment within a transplant region of the recipient skeletal fragment; and creating a hybrid computer-readable representation comprising the recipient skeletal fragment and the portion of the donor skeletal. |
| FILED | Wednesday, October 14, 2020 |
| APPL NO | 17/070327 |
| ART UNIT | 2677 — Facsimile; Printer; Color; halftone; Scanner; Computer Graphic Processing; 3-D Animation; Display Color; Attributes; Object Processing; Hardware and Memory |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/15 (20130101) A61B 17/176 (20130101) A61B 17/1695 (20130101) A61B 17/1739 (20130101) A61B 17/8085 (20130101) A61B 34/10 (20160201) A61B 34/20 (20160201) A61B 2034/105 (20160201) A61B 2034/108 (20160201) A61B 2034/2051 (20160201) A61B 2034/2055 (20160201) A61B 2034/2065 (20160201) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2803 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/40 (20180101) G16H 30/40 (20180101) Original (OR) Class G16H 50/50 (20180101) Technologies for Adaptation to Climate Change Y02A 90/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11329831 | Traynor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Patrick G. Traynor (Gainesville, Florida); Bradley G. Reaves (Raleigh, North Carolina); Logan E. Blue (Palm Bay, Florida) |
| ABSTRACT | Methods and apparatuses for providing cryptographic authentication within a voice channel are disclosed. The methods and apparatuses can provide cryptographic authentication solely within a voice channel or can use a combination of a voice channel and another data channel. A method for providing cryptographic authentication within a voice channel can operate between telephonic systems and be suitable for operating over G.711/PCMu, AMR and SPEEX™ codecs, and suitable for operating over mobile, PSTN, and VOIP networks. The method can include providing a modem that is codec agnostic and suitable for executing a TLS-based authentication protocol. The method can include using frequency-shift modulation within a frequency range of 300-3400 Hz. |
| FILED | Thursday, June 08, 2017 |
| APPL NO | 16/304412 |
| ART UNIT | 2494 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0825 (20130101) H04L 9/3066 (20130101) H04L 9/3242 (20130101) H04L 9/3268 (20130101) Original (OR) Class H04L 27/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11330170 | Seibel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| INVENTOR(S) | Eric J. Seibel (Seattle, Washington); Brian T. Schowengerdt (Seattle, Washington) |
| ABSTRACT | Methods and systems for acquiring and/or projecting images from and/or to a target area are provided. Such a method or system can include an optical fiber assembly which may be driven to scan the target area in a scan pattern. The optical fiber assembly may provide multiple effective light sources (e.g., via a plurality of optical fibers) that are axially staggered with respect to an optical system located between the optical fiber and the target area. The optical system may be operable to focus and/or redirect the light from the multiple light sources onto separate focal planes. A composite image may be generated based on light reflected from and/or projected onto the separate focal planes. The composite image may have an extended depth of focus or field spanning over a distance between the separate focal planes while maintaining or improving image resolution. |
| FILED | Tuesday, December 10, 2019 |
| APPL NO | 16/708728 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/07 (20130101) A61B 1/00167 (20130101) A61B 1/00172 (20130101) A61B 1/00188 (20130101) A61B 1/0623 (20130101) Optical Elements, Systems, or Apparatus G02B 23/26 (20130101) G02B 23/2469 (20130101) G02B 26/103 (20130101) G02B 27/40 (20130101) Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor G03B 21/142 (20130101) Pictorial Communication, e.g Television H04N 5/23235 (20130101) Original (OR) Class H04N 5/232125 (20180801) H04N 5/232939 (20180801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11324516 | Kosiorek et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Christopher B. Kosiorek (La Vernia, Texas); Dexter C. Drayton (San Antonio, Texas); Esra Abir (New York, New York); Neslihan Damar (Istanbul, Turkey); Nilufer Polat (Brooklyn, New York); Yavuz Avci (Sunnyside, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher B. Kosiorek (La Vernia, Texas); Dexter C. Drayton (San Antonio, Texas); Esra Abir (New York, New York); Neslihan Damar (Istanbul, Turkey); Nilufer Polat (Brooklyn, New York); Yavuz Avci (Sunnyside, New York) |
| ABSTRACT | A pre-fabricated pneumatic tourniquet apparatus and related methods are provided. The tourniquet is easy to apply, ensures consistent and even circumferential pressure, is light weight, provides standard life saving operation, and can be utilized in any setting or situation. The pneumatic tourniquet apparatus is comprised of a bladder, a reservoir chassis, a retaining cover, a receiver and a slider. The bladder is elongated in shaped—long enough to wrap around most human limbs. |
| FILED | Friday, March 29, 2019 |
| APPL NO | 16/369902 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/135 (20130101) Original (OR) Class A61B 17/1327 (20130101) A61B 90/90 (20160201) A61B 2017/00526 (20130101) A61B 2017/00544 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49826 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11324612 | Hansen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Andrew H. Hansen (Apple Valley, Minnesota); Eric A. Nickel (Brooklyn Park, Minnesota); Billie Caris Savvas Slater (Mendota Heights, Minnesota); Stuart R. Fairhurst (Minneapolis, Minnesota); Jennifer Leestma (Wayzata, Minnesota) |
| ABSTRACT | A liner defines a pouch, an opening, a cup, and a first ring positioned on the pouch distal to the opening. The pouch is air-permeable and defines an internal volume for receiving a residual limb. The opening defined by the pouch provides access to the internal volume. The cup is air-impermeable and is positioned on the pouch distal to the opening. The liner is combined with an adapter for connecting a residual limb to a prosthetic limb. The adapter has a socket for receiving the cup, at least one hole positioned within the socket for drainage therefrom and sleeve extending from the socket and surrounding a central space. The adapter also has at least one vent positioned in the sleeve and overlies the air permeable material. |
| FILED | Friday, September 18, 2020 |
| APPL NO | 17/025008 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/60 (20130101) A61F 2/78 (20130101) A61F 2/80 (20130101) A61F 2/7812 (20130101) Original (OR) Class A61F 2002/802 (20130101) A61F 2002/805 (20130101) A61F 2002/807 (20130101) A61F 2002/7837 (20130101) A61F 2002/7893 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11324655 | De Rossi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Stefano Marco Maria De Rossi (Cambridge, United Kingdom); Kathleen Elizabeth O'Donnell (Cambridge, Massachusetts); Jaehyun Bae (Cambridge, Massachusetts); Alan Thomas Asbeck (Waltham, Massachusetts); Kenneth G. Holt (Shutesbury, Massachusetts); Conor J. Walsh (Cambridge, Massachusetts) |
| ABSTRACT | In at least some aspects, the present concepts include a method for configuring an assistive flexible suit including the acts of outfitting a person with an assistive flexible suit, monitoring an output of at least one sensor of the assistive flexible suit as the person moves in a first controlled movement environment, identifying at least one predefined gait event using the output of the at least one sensor, adjusting an actuation profile of the at least one actuator and continuing to perform the acts of monitoring, identifying and adjusting until an actuation profile of the at least one actuator generates a beneficial moment about the at least one joint to promote an improvement in gait. The at least one controller is then set to implement the actuation profile. |
| FILED | Wednesday, December 03, 2014 |
| APPL NO | 15/102694 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/112 (20130101) A61B 5/4851 (20130101) A61B 5/6811 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/72 (20130101) A61F 5/0102 (20130101) A61F 5/0127 (20130101) A61F 13/08 (20130101) A61F 2005/0155 (20130101) A61F 2005/0158 (20130101) A61F 2005/0179 (20130101) A61F 2005/0188 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/024 (20130101) A61H 1/0244 (20130101) A61H 1/0266 (20130101) A61H 3/00 (20130101) Original (OR) Class A61H 2201/14 (20130101) A61H 2201/164 (20130101) A61H 2201/165 (20130101) A61H 2201/169 (20130101) A61H 2201/501 (20130101) A61H 2201/1207 (20130101) A61H 2201/1623 (20130101) A61H 2201/1628 (20130101) A61H 2201/5028 (20130101) A61H 2201/5061 (20130101) A61H 2201/5064 (20130101) A61H 2201/5079 (20130101) A61H 2201/5084 (20130101) A61H 2230/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11324857 | Christ et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wake Forest University Health Sciences (Winston-Salem, North Carolina) |
| ASSIGNEE(S) | Wake Forest University Health Sciences (Winston-Salem, North Carolina) |
| INVENTOR(S) | George J. Christ (Crozet, Virginia); Benjamin T. Corona (Converse, Texas) |
| ABSTRACT | Provided herein are methods of culturing organized skeletal muscle tissue from precursor muscle cells by cyclically stretching and relaxing said muscle cells on a support in vitro for a time sufficient to produce said organized skeletal muscle tissue, including reseeding said organized skeletal muscle tissue by contacting additional precursor muscle cells to said organized skeletal muscle tissue on said solid support, and then repeating said step of cyclically stretching and relaxing said muscle cells in said support in vitro for time sufficient to enhance the density (i.e., increased number of nuclei and/or number of multinucleated cells) of said organized skeletal muscle tissue on said support. |
| FILED | Wednesday, December 14, 2016 |
| APPL NO | 15/378534 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/08 (20130101) A61F 2002/0894 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) A61K 35/34 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/3826 (20130101) A61L 27/3873 (20130101) A61L 27/3895 (20130101) Original (OR) Class Apparatus for Enzymology or Microbiology; C12M 35/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0658 (20130101) C12N 5/0697 (20130101) C12N 2527/00 (20130101) C12N 2533/54 (20130101) C12N 2533/90 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11324955 | Wheeler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Jesse J. Wheeler (East Boston, Massachusetts); Philip D. Parks (Jamaica Plain, Massachusetts); James E. Moran (Methuen, Massachusetts); Andrew Czarnecki (Cambridge, Massachusetts); Keith B. Baldwin (Braintree, Massachusetts); David Goldberg (Cambridge, Massachusetts); Alex Kindle (Cambridge, Massachusetts); Marc W. McConley (Andover, Massachusetts) |
| ABSTRACT | The systems and methods described herein include an external base station with a tethered transceiver, an implanted hub that includes power, telemetry, and processing electronics, and a plurality of implanted satellite that contain reconfigurable front-end electronics for interfacing with electrodes. The system can operate in different modes. In a first mode, called a base boost mode, the external base station is used for closed-loop control of stimulation therapies. In a second, autonomous mode, closed-loop control is performed in the hub without direct influence from the base station. In a third mode, streams of neural data are transmitted to an offline processor for offline analysis. |
| FILED | Tuesday, June 04, 2019 |
| APPL NO | 16/431428 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/377 (20210101) A61B 5/4836 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0534 (20130101) A61N 1/36064 (20130101) A61N 1/36082 (20130101) A61N 1/36125 (20130101) A61N 1/36139 (20130101) Original (OR) Class A61N 1/37217 (20130101) A61N 1/37276 (20130101) Transmission H04B 1/385 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 41/0806 (20130101) H04L 43/16 (20130101) Wireless Communication Networks H04W 4/80 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325086 | Stroud et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Rhonda M. Stroud (Washington, District of Columbia); Matthew J. Crane (Seattle, Washington); Peter J. Pauzauskie (Seattle, Washington) |
| ABSTRACT | A method of making molecularly doped nanodiamond. A versatile method for doping diamond by adding dopants into a carbon precursor and producing diamond at high pressure, high temperature conditions. Molecularly doped nanodiamonds that have direct incorporation of dopants and therefore without the need for ion implantation. Molecularly-doped diamonds that have fewer lattice defects than those made with ion implantation. |
| FILED | Friday, March 08, 2019 |
| APPL NO | 16/297338 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 3/062 (20130101) Original (OR) Class B01J 13/0091 (20130101) B01J 2203/062 (20130101) B01J 2203/0625 (20130101) B01J 2203/0655 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/26 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/52 (20130101) C01P 2002/82 (20130101) C01P 2002/84 (20130101) C01P 2004/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325100 | Roberts et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Courtney A. Roberts (Washington, District of Columbia); R. Andrew McGill (Lorton, Virginia) |
| ABSTRACT | The invention relates to strong hydrogen-bond acidic sorbents. The sorbents may be provided in a form that limits or eliminates intramolecular bonding of the hydrogen-bond acidic site between neighboring sorbent molecules, for example, by providing steric groups adjacent to the hydrogen-bond acidic site. The hydrogen bond site may be a phenolic structure based on a bisphenol architecture. The sorbents of the invention may be used in methods for trapping or detecting hazardous chemicals or explosives. |
| FILED | Thursday, November 01, 2018 |
| APPL NO | 16/178488 |
| ART UNIT | 1796 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/22 (20130101) Original (OR) Class B01J 20/282 (20130101) B01J 20/3425 (20130101) B01J 20/3483 (20130101) B01J 20/28023 (20130101) B01J 2220/54 (20130101) Acyclic or Carbocyclic Compounds C07C 39/367 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 14/06 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 59/00 (20130101) C08G 64/00 (20130101) C08G 64/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/482 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325114 | Aizenberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Joanna Aizenberg (Boston, Massachusetts); Tanya Shirman (Arlington, Massachusetts); Nicolas Vogel (Cambridge, Massachusetts); Mathias Kolle (Hull, Massachusetts); Michael Aizenberg (Boston, Massachusetts) |
| ABSTRACT | Methods for forming an interconnected network of solid material and pores, with metal residing only at the air/solid interface of the interconnected network structure are described. In certain embodiments, nanoparticle decorated sacrificial particles can be used as sacrificial templates for the formation of a porous structure having an interconnected network of solid material and interconnected network of pores. The nanoparticles reside predominantly at the air/solid interface and allow further growth and accessibility of the nanoparticles at defined positions of the interconnected structure. SEM and TEM measurements reveal the formation of 3D interconnected porous structures with nanoparticles residing predominantly at the air/solid interface of the interconnected structure. |
| FILED | Monday, April 22, 2019 |
| APPL NO | 16/391053 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/52 (20130101) B01J 35/10 (20130101) Original (OR) Class B01J 37/0018 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/01 (20130101) C04B 38/06 (20130101) C04B 38/0074 (20130101) C04B 38/0096 (20130101) C04B 38/0096 (20130101) C04B 2111/0081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325119 | NG Pitti et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Carlos Francisco NG Pitti (Jamaica Plain, Massachusetts); Ulri Nicole Lee (Seattle, Washington); Richard Novak (Boston, Massachusetts); Olivier Yves Frederic Henry (Brookline, Massachusetts); Remco Van Erp (Sint Anthonis, Netherlands); Donald E. Ingber (Boston, Massachusetts) |
| ABSTRACT | A fluidic device includes a fluidic layer, a capture material, and an electronics layer, the fluidic layer includes a main channel and a pair of sample channels fluidly coupled to the main channel. The pair of sample channels is configured to receive and introduce a sample material into the device. The sample material includes an analyte. The capture material is positioned in a portion of the main channel that is spaced from the pair of sample channels. The capture material has a three-dimensional matrix of receptors therein configured to bond with the analyte. The capture material has a length that is associated with a dynamic range of the fluidic device and a cross-sectional area that is associated with a sensitivity of the fluidic device. The electronics layer includes electrodes configured to measure an electrical resistance through a portion of the capture material. |
| FILED | Wednesday, March 14, 2018 |
| APPL NO | 16/494230 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) Original (OR) Class B01L 3/502715 (20130101) B01L 2300/069 (20130101) B01L 2300/0645 (20130101) B01L 2300/0867 (20130101) B01L 2300/0896 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/08 (20130101) G01N 33/48707 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325335 | Johnson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretarv of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Scooter David Johnson (Hyattsville, Maryland); Jeffrey Wang Xing (Irvine, California); Michael Doherty (Chantilly, Virginia) |
| ABSTRACT | Disclosed herein is a method and apparatus for forming pellets in a non-ambient environment such as a strong magnetic field. The apparatus includes a die body, a die bottom, a short push pin, a long push pin, a press tube, and an extended push pin. A powder is loaded into the die body, which is then positioned in the non-ambient environment, and the powder allowed to equilibrate. A pellet is then formed by pressing on the extended push pin while the powder is in the non-ambient environment. |
| FILED | Wednesday, August 07, 2019 |
| APPL NO | 16/534283 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/03 (20130101) B22F 3/004 (20130101) B22F 2003/033 (20130101) B22F 2999/00 (20130101) Presses in General B30B 7/00 (20130101) B30B 15/304 (20130101) Original (OR) Class Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 41/0266 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325700 | Maxwell |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Jesse R. Maxwell (Silver Spring, Maryland) |
| ABSTRACT | A method of designing a hypersonic vehicle includes selecting a shock shape; tracing a leading edge along the shock shape; selecting a base plane defining endpoints of the leading edge and rearwardly displaced from a front of the leading edge; and tracing stream surfaces back from the leading edge along the shock to the base plane in order to define an upper surface and a lower surface, wherein the upper and lower surfaces and base plane enclose a volume representing internal volume of the hypersonic vehicle. The lower stream surface is controllably morphable. |
| FILED | Monday, July 23, 2018 |
| APPL NO | 16/042622 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 1/0009 (20130101) B64C 3/48 (20130101) B64C 30/00 (20130101) Original (OR) Class B64C 2001/0045 (20130101) B64C 2003/445 (20130101) Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325867 | Xu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida); The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida); THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as Represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Chengying Xu (Tallahassee, Florida); William C. Nickerson (Ashburn, Virginia) |
| ABSTRACT | Hybrid composite materials including carbon nanotube sheets and flexible ceramic materials, and methods of making the same are provided herein. In one embodiment, a method of forming a hybrid composite material is provided, the method including: placing a layer of a first flexible ceramic composite on a lay-up tooling surface; applying a sheet of a pre-preg carbon fiber reinforced polymer on the flexible ceramic composite; curing the flexible ceramic composite and the pre-preg carbon fiber reinforced polymer sheet together to form a hybrid composite material; and removing the hybrid composite material from the lay-up tooling surface, wherein the first flexible ceramic composite comprises an exterior surface of the hybrid composite material. |
| FILED | Friday, January 31, 2020 |
| APPL NO | 16/778088 |
| ART UNIT | 1783 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 70/30 (20130101) B29C 70/78 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/022 (20130101) B32B 9/007 (20130101) B32B 18/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/80 (20130101) Original (OR) Class C04B 35/589 (20130101) C04B 41/85 (20130101) C04B 41/4501 (20130101) C04B 41/5001 (20130101) C04B 2235/77 (20130101) C04B 2235/95 (20130101) C04B 2235/96 (20130101) C04B 2235/616 (20130101) C04B 2235/3217 (20130101) C04B 2235/5288 (20130101) C04B 2235/9607 (20130101) C04B 2235/9615 (20130101) C04B 2235/9684 (20130101) C04B 2237/38 (20130101) C04B 2237/365 (20130101) C04B 2237/368 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/30 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325944 | Aldrich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Jane V. Aldrich (Gainesville, Florida); Laura E. Hanold (Gainesville, Florida) |
| ABSTRACT | The invention relates to macrocyclic peptides and pharmaceutical compositions thereof. The invention further relates to pharmaceutical compositions for modulating opioid receptor activity. |
| FILED | Friday, June 15, 2018 |
| APPL NO | 16/622749 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 5/126 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325962 | Finn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Olivera J. Finn (Pittsburgh, Pennsylvania); Nehad M. Alajez (Riyadh, Saudi Arabia); Jan Schmielau (Lubeck, Germany); Mark D. Alter (Brooklyn, New York) |
| ABSTRACT | The invention provides an isolated nucleic acid encoding a receptor, other than an immunoglobulin, wherein the receptor binds to a MUC1 tumor antigen independently of an major histocompatibility complex (MHC). The invention provides a method of activating a signaling pathway and/or killing a cancer cell using a receptor that is similar to or is a T cell receptor. |
| FILED | Wednesday, March 27, 2019 |
| APPL NO | 16/366885 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/00 (20130101) Peptides C07K 14/7051 (20130101) Original (OR) Class C07K 14/70503 (20130101) C07K 16/2809 (20130101) C07K 16/3092 (20130101) C07K 2317/34 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2799/027 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57492 (20130101) G01N 2333/4725 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326015 | Davis |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Matthew C. Davis (Ridgecrest, California) |
| ABSTRACT | A method for making a cyanate ester resin includes reacting an arylorganometallic agent with a phosphorous halide in a solvent forming methoxy functionalized triphenylphosphines with one to six meta-methoxy groups. The methoxy functionalized triphenylphosphines with one to six meta-methoxy groups are reacted with an oxidizing agent forming a methoxy functionalized triphenylphosphine oxide including one to six meta-methoxy groups. The methoxy functionalized triphenylphosphine oxide is reacted with a dealkylating agent forming a hydroxy substituted triphenylphosphineoxide including one to six meta-hydroxyl groups. The hydroxy substituted triphenylphosphineoxide is reacted with cyanating reagent and a base forming a substituted triphenylphosphine oxide including one to six meta-cyanate groups. The substituted triphenylphosphine oxide is polymerized forming the cyanate ester resin. |
| FILED | Friday, February 01, 2019 |
| APPL NO | 16/265336 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/5022 (20130101) C07F 9/5054 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/022 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326121 | Collett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | METSS Corp. (Westerville, Ohio) |
| ASSIGNEE(S) | METSS Corp. (Westerville, Ohio) |
| INVENTOR(S) | Brian R. Collett (Columbus, Ohio); Angela Theys (Kansas City, Missouri); Michelle Docter (Columbus, Ohio); Joseph Sanders (Powell, Ohio); Kenneth J. Heater (Delaware, Ohio) |
| ABSTRACT | Lubricating compositions are described, the lubricating compositions comprising a base oil component and an additive component, wherein the additive component comprises a non-silicone anti-foaming agent. |
| FILED | Tuesday, July 06, 2021 |
| APPL NO | 17/367964 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition C10M 101/00 (20130101) C10M 107/10 (20130101) C10M 129/34 (20130101) C10M 133/12 (20130101) C10M 133/44 (20130101) C10M 137/04 (20130101) C10M 145/14 (20130101) Original (OR) Class C10M 169/044 (20130101) C10M 2205/0285 (20130101) C10M 2207/123 (20130101) C10M 2209/084 (20130101) C10M 2215/06 (20130101) C10M 2215/223 (20130101) C10M 2223/041 (20130101) Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions C10N 2020/02 (20130101) C10N 2030/06 (20130101) C10N 2030/10 (20130101) C10N 2030/12 (20130101) C10N 2030/14 (20130101) C10N 2030/18 (20130101) C10N 2030/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326464 | Taketa et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana); Rolls-Royce Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana); Rolls-Royce Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Linnea Taketa (Indianapolis, Indiana); John Munson (Indianapolis, Indiana); Ted J. Freeman (Danville, Indiana) |
| ABSTRACT | A turbomachinery component of a gas turbine engine is disclosed having a number of techniques of reducing the effects of a gap flow between an airfoil member of the gas turbine engine and a wall of the gas turbine engine. The airfoil member can be variable and in one form is a variable turbine vane. In one embodiment a brush seal is included between the vane and the wall. In another form a wear surface is disposed between the vane and the wall. In yet another form a moveable member capable of being actuated to change position can be disposed between the vane and the wall to alter the size of a gap between the two. |
| FILED | Wednesday, June 26, 2019 |
| APPL NO | 16/453438 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/28 (20130101) F01D 9/041 (20130101) F01D 11/00 (20130101) F01D 11/02 (20130101) F01D 11/005 (20130101) Original (OR) Class F01D 11/025 (20130101) F01D 11/122 (20130101) F01D 17/148 (20130101) F01D 17/162 (20130101) F01D 17/165 (20130101) Non-positive-displacement Pumps F04D 19/02 (20130101) F04D 27/002 (20130101) F04D 27/0246 (20130101) F04D 29/083 (20130101) F04D 29/164 (20130101) Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G F05B 2240/571 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/56 (20130101) Pistons; Cylinders; Sealings F16J 15/3288 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326569 | Perr |
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| FUNDED BY |
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| APPLICANT(S) | ACHATES POWER, INC. (San Diego, California) |
| ASSIGNEE(S) | Achates Power, Inc. (San Diego, California) |
| INVENTOR(S) | Andrew P. Perr (Columbus, Indiana) |
| ABSTRACT | A fuel injector mounting assembly in an opposed-piston engine allows for mounting of a fuel injector in a cylinder block without significantly deforming the wall of the cylinder into which the injector is configured to deliver fuel. The fuel injector mounting assembly includes a clamping arrangement to clamp the fuel injector to the cylinder block, an elongate tubular sleeve that sheathes a nozzle portion of the fuel injector, and a spanner nut attached to the elongate tubular sleeve. Clamping loads applied to retain the fuel injector in the cylinder block are controlled by the spanner nut. |
| FILED | Monday, November 25, 2019 |
| APPL NO | 16/694861 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Internal-combustion Piston Engines; Combustion Engines in General F02B 75/28 (20130101) F02B 2275/14 (20130101) Cylinders, Pistons or Casings, for Combustion Engines; Arrangements of Sealings in Combustion Engines F02F 1/186 (20130101) F02F 7/0068 (20130101) F02F 11/005 (20130101) Supplying Combustion Engines in General With Combustible Mixtures or Constituents Thereof F02M 61/14 (20130101) Original (OR) Class F02M 2200/858 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326617 | Greene et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Christopher Britton Greene (East Hartford, Connecticut); Dustin Joseph Frohnapfel (Bloomfield, Connecticut) |
| ABSTRACT | A boost compressor assembly may comprise an outer annular structure and a plurality of blades. Each blade in the plurality of blades may be moveably coupled to the outer annular structure. The plurality of blades may be configured to deploy in response to the boost compressor assembly rotating. The plurality of blades may be configured to retract when the boost compressor assembly stops rotating. |
| FILED | Tuesday, January 14, 2020 |
| APPL NO | 16/742591 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 7/02 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/06 (20130101) Jet-propulsion Plants F02K 3/06 (20130101) Non-positive-displacement Pumps F04D 29/366 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/80 (20130101) F05D 2260/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326717 | Huff |
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| FUNDED BY |
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| APPLICANT(S) | CORPORATION FOR NATIONAL RESEARCH INITIATIVES (Reston, Virginia) |
| ASSIGNEE(S) | CORPORATION FOR NATIONAL RESEARCH INITIATIVES (Reston, Virginia) |
| INVENTOR(S) | Michael Huff (Oakton, Virginia) |
| ABSTRACT | A three-way (3-way) Micro-Electro-Mechanical Systems (MEMS)-based micro-valve device and method of fabrication for the implementation of a three-way MEMS-based micro-valve which uses a single piezoelectric actuator. The present invention has a wide range of applications including medical, industrial control, aerospace, automotive, consumer electronics and products, as well as any application(s) requiring the use of three-way micro-valves for the control of fluids. The present invention allows for the implementation of a three-way microvalve device and method of fabrication that can be tailored to the requirements of a wide range of applications and fluid types. The microvalve may employ a novel pressure-balancing scheme wherein the fluid pressure balances the actuator mechanism so that only a small amount of actuation pressure (or force) is needed to switch the state of the actuator and device from open to closed, or closed to open. |
| FILED | Monday, February 12, 2018 |
| APPL NO | 15/894716 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 99/0015 (20130101) Original (OR) Class F16K 99/0028 (20130101) F16K 99/0048 (20130101) F16K 2099/008 (20130101) F16K 2099/0073 (20130101) F16K 2099/0078 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326781 | Rudrapatna et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HONEYWELL INTERNATIONAL INC. (Charlotte, North Carolina) |
| ASSIGNEE(S) | HONEYWELL INTERNATIONAL INC. (Charlotte, North Carolina) |
| INVENTOR(S) | Nagaraja S. Rudrapatna (Chandler, Arizona); Ian Critchley (Prescott, Arizona); Jeffrey Spencer (Tempe, Arizona); Philip Smalley (Tempe, Arizona) |
| ABSTRACT | A liner for a combustor includes a first wall and a second wall extending around at least a portion of the first wall to form a liner cavity with the first wall. The first wall defines a first wall orifice and the second wall defines a second wall orifice. The liner further includes a first insert mounted on the second wall within the second wall orifice and extending through the first wall orifice. The first insert is configured to direct a first air jet through the second wall and the first wall. The first insert is formed by a tubular body portion extending through the first wall orifice and the second wall orifice, and a shoulder extending around the body portion that abuts the first side of the second wall. The shoulder has a first diameter and the first wall orifice has a second diameter, greater than the first diameter. |
| FILED | Tuesday, September 22, 2020 |
| APPL NO | 17/028559 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) F23R 3/06 (20130101) Original (OR) Class F23R 3/50 (20130101) F23R 2900/00017 (20130101) F23R 2900/03041 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326884 | Vahala et al. |
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| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Kerry Vahala (Pasadena, California); Jiang Li (Pasadena, California); Yu-Hung Lai (Pasadena, California); Myoung-Gyun Suh (Pasadena, California); Seung Hoon Lee (Pasadena, California) |
| ABSTRACT | A disk resonator is pumped by counterpropagating pump signals to produce corresponding counterpropagating Brillouin laser signals. The pump laser optical frequencies are separated by a frequency offset ΔνP but excite the same nominal resonator optical mode; the Brillouin laser optical frequencies are separated by a beat frequency ΔνL with 0<ΔνL<ΔνP. A photodetector receives the Brillouin laser signals and produces an electrical signal at the beat frequency ΔνL. The frequency offset ΔνP can be large so enough to prevent locking of the Brillouin laser signals onto a common Brillouin laser frequency. A signal processing system derives from the beat frequency ΔνL an estimated angular velocity component of the disk optical resonator about an axis substantially perpendicular to the disk optical resonator. |
| FILED | Wednesday, February 12, 2020 |
| APPL NO | 16/789404 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/64 (20130101) G01C 19/661 (20130101) G01C 19/665 (20130101) G01C 19/727 (20130101) Original (OR) Class Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/30 (20130101) H01S 3/0085 (20130101) H01S 3/094096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326937 | Lal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Amit Lal (Ithaca, New York); Sahil Gupta (Easton, Connecticut); Sachin Nadig (Ithaca, New York); Benyamin Davaji (Ithaca, New York) |
| ABSTRACT | A vibration transducer module for detecting a vibratory signal, comprising a base, a spring connected to the base at a first location, a mass mechanically coupled to the spring at a second location remote from the first location, and a wall configured to position a first wall electrode and a second wall electrode a selected distance from the first location, the conductive element positioned and sized to contact the first wall electrode and the second wall electrode. The mass comprises a conductive element, and an energy harvester to provide a first voltage signal. The energy harvester may comprise a piezoelectric material or be construct as a SAW device. The module may be combined with a rectifier and an oscillator to form a vibration sensor. |
| FILED | Wednesday, May 10, 2017 |
| APPL NO | 16/099584 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 11/02 (20130101) G01H 11/08 (20130101) Original (OR) Class Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 35/14 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/22 (20130101) Dynamo-electric Machines H02K 35/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326964 | Hubble |
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| FUNDED BY |
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| APPLICANT(S) | David O. Hubble (King George, Virginia) |
| ASSIGNEE(S) | United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | David O. Hubble (King George, Virginia) |
| ABSTRACT | A calorimeter board is provided for power calibration of a laser emission. The board includes a flat metal plate, a sinuous groove and a resistance temperature detector wire. The flat metal plate has obverse and reverse surfaces separated by a thickness. The groove is cut into the reverse surface and penetrates to a depth being part of the thickness. The wire is disposed within the groove at the depth. The wire connects to an instrument that measures electrical resistance responsive to the laser emission on the obverse surface. |
| FILED | Wednesday, April 08, 2020 |
| APPL NO | 16/842950 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 7/16 (20130101) G01K 17/003 (20130101) G01K 19/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326970 | Williams et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jeremiah C Williams (Dayton, Ohio); Hengky Chandrahalim (Beavercreek, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Jeremiah C Williams (Dayton, Ohio); Hengky Chandrahalim (Beavercreek, Ohio) |
| ABSTRACT | A passive microscopic Fabry-Pérot Interferometer (FPI) pressure sensor includes an optical fiber and a three-dimensional microscopic optical enclosure. The three-dimensional microscopic optical enclosure includes tubular side walls having lateral pleated corrugations and attached to a cleaved tip of the optical fiber to receive a light signal. An optically reflecting end wall is distally engaged to the tubular side walls to enclose a trapped quantity of gas that longitudinally positions the optically reflecting end wall in relation to ambient air pressure, changing a distance traveled by a light signal reflected back through the optical fiber. |
| FILED | Wednesday, April 14, 2021 |
| APPL NO | 17/229986 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 11/025 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 6/29359 (20130101) G02B 6/29395 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11327016 | Diebold et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Eric D. Diebold (Los Angeles, California); Bahram Jalali (Los Angeles, California); Brandon Buckley (Los Angeles, California) |
| ABSTRACT | Apparatus and methods for fluorescence imaging using radiofrequency multiplexed excitation. One apparatus splits an excitation laser beam into two arms of a Mach-Zehnder interferometer. The light in the first beam is frequency shifted by an acousto-optic deflector, which is driven by a phase-engineered radiofrequency comb designed to minimize peak-to-average power ratio. This RF comb generates multiple deflected optical beams possessing a range of output angles and frequency shifts. The second beam is shifted in frequency using an acousto-optic frequency shifter. After combining at a second beam splitter, the two beams are focused to a line on the sample using a conventional laser scanning microscope lens system. The acousto-optic deflectors frequency-encode the simultaneous excitation of an entire row of pixels, which enables detection and de-multiplexing of fluorescence images using a single photomultiplier tube and digital phase-coherent signal recovery techniques. |
| FILED | Wednesday, July 31, 2019 |
| APPL NO | 16/528436 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/05 (20130101) G01N 21/6408 (20130101) Original (OR) Class G01N 21/6458 (20130101) G01N 21/6486 (20130101) G01N 2021/6415 (20130101) G01N 2021/6419 (20130101) G01N 2201/06113 (20130101) Optical Elements, Systems, or Apparatus G02B 21/16 (20130101) G02B 21/0076 (20130101) G02B 21/0084 (20130101) G02B 27/1006 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11327018 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Somin Eunice Lee (Ann Arbor, Michigan); Yunbo Liu (Ann Arbor, Michigan); Yipei Wang (Ann Arbor, Michigan) |
| ABSTRACT | An image reconstruction method includes capturing a reference image of the specimen and capturing a set of original images based on the reference image. The method includes generating a set of analyzed images based on the set of original images by determining an intensity distribution for each pixel of each original image of the set of original images and combining the intensity distribution at each pixel location across the set of original images into an intermediate image. The method includes, identifying an object in the intermediate image. In response to identifying the object in the intermediate image, determining an intensity value of the object in each original image of the set of original images and generating an improved image of the object based on the determined intensity value of the object. The method includes generating a final image including the improved image of the object and displaying the final image. |
| FILED | Friday, April 12, 2019 |
| APPL NO | 17/047124 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 21/6445 (20130101) G01N 21/6458 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 21/367 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11327041 | Johnson, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Alan T. Johnson, Jr. (Philadelphia, Pennsylvania); Jinglei Ping (Gaithersburg, Maryland) |
| ABSTRACT | Provided are devices and methods for a rapid, non-perturbative and energy-efficient technique for pH sensing based on a flexible graphene electrode. This technique does not require the application of gate voltage or source-drain bias, and demonstrates fast pH-characterization with precision. The disclosed technology is suitable for in vivo monitoring of tumor-induced pH variation in tissues and detection of pH changes as required in a DNA sequencing system. |
| FILED | Monday, March 13, 2017 |
| APPL NO | 16/085014 |
| ART UNIT | 1759 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/36 (20130101) G01N 27/302 (20130101) G01N 27/308 (20130101) Original (OR) Class G01N 27/4167 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11327201 | Wood et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Warren Theodore Wood (Mandeville, Louisiana); Kylara Margaret Martin (Round Rock, Texas) |
| ABSTRACT | Systems and methods relate to generating a self-consistent sediment model. Initially, void ratio extrema are determined for each sediment layer in a sediment column based on historical data or a direct measurement of the sediment column. Initial stress is determined for each sediment layer based on the void ratio extrema. A porosity model is generated for each sediment layer based on the void ratio extrema and the initial stress. At this stage, measured data is obtained for each sediment layer from a data collection device positioned at or near a geographic location of the sediment column. The porosity model of each of the sediment layer is combined with the measured data of the sediment layer to generate the self-consistent sediment model for each sediment layer. The porosity model and the self-consistent sediment model of each sediment layer is updated based on updated measured data obtained from the data collection device. |
| FILED | Tuesday, October 31, 2017 |
| APPL NO | 15/799494 |
| ART UNIT | 2148 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/088 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 1/3808 (20130101) G01V 99/005 (20130101) Original (OR) Class G01V 2210/66 (20130101) G01V 2210/6244 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11327225 | Koch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Thomas L. Koch (Tucson, Arizona); Robert A. Norwood (Tucson, Arizona); Stanley K. H. Pau (Tucson, Arizona); Nasser N. Peyghambarian (Tucson, Arizona) |
| ABSTRACT | A flexible polymer waveguide array structure serves as a stitch or jumper on an optical printed circuit board (OPCB). The flexible polymer waveguide array structure can be attached to the OPCB so that it can provide a chip-to-OPCB optical connection. The waveguide(s) in the flexible polymer waveguide array structure may be prefabricated before the flexible polymer waveguide array structure is attached to the OPCB. Alternatively, the waveguides may be fabricated after the flexible polymer waveguide array structure has been attached to the OPCB. The waveguide(s) may be subsequently formed using a printing process such as photolithography. As a consequence of forming the waveguide(s) after attachment of the flexible polymer waveguide array to the OPCB, the precision in the lateral alignment that is required when placing the flexible polymer waveguide array structure on the OPCB is generally significantly less than is required when the waveguide(s) are prefabricated. |
| FILED | Friday, April 28, 2017 |
| APPL NO | 16/094886 |
| ART UNIT | 2896 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/13 (20130101) G02B 6/12002 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11327900 | Duncan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NVIDIA Corporation (Santa Clara, California) |
| ASSIGNEE(S) | NVIDIA Corporation (Santa Clara, California) |
| INVENTOR(S) | Samuel Hammond Duncan (Arlington, Massachusetts); Sanjeev Jain (Chandler, Arizona); Mark Douglas Hummel (Franklin, Massachusetts); Vyas Venkataraman (Sharon, Massachusetts); Olivier Giroux (Santa Clara, California); Larry Robert Dennison (Mendon, Massachusetts); Alexander Toichi Ishii (Lebanon, New Hampshire); Hemayet Hossain (San Jose, California); Nir Haim Arad (Snoqualmie, Washington) |
| ABSTRACT | Multiprocessor clusters in a virtualized environment conventionally fail to provide memory access security, which is frequently a requirement for efficient utilization in multi-client settings. Without adequate access security, a malicious process may access what might be confidential data that belongs to a different client sharing the multiprocessor cluster. Furthermore, an inadvertent programming error in the code for one client process may accidentally corrupt data that belongs to the different client. Neither scenario is acceptable. Embodiments of the present disclosure provide access security by enabling each processing node within a multiprocessor cluster to virtualize and manage local memory access and only process access requests possessing proper access credentials. In this way, different applications executing on a multiprocessor cluster may be isolated from each other while advantageously sharing the hardware resources of the multiprocessor cluster. |
| FILED | Thursday, July 23, 2020 |
| APPL NO | 16/937296 |
| ART UNIT | 2137 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 12/1027 (20130101) Original (OR) Class G06F 2212/68 (20130101) G06F 2212/1044 (20130101) G06F 2212/1052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11328206 | Chai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | SRI Inlernational (Menlo Park, California) |
| INVENTOR(S) | Sek M. Chai (Princeton, New Jersey); David C. Zhang (Belle Mead, New Jersey); Mohamed R. Amer (Brooklyn, New York); Timothy J. Shields (Houston, Texas); Aswin Nadamuni Raghavan (Princeton, New Jersey); Bhaskar Ramamurthy (Menlo Park, California) |
| ABSTRACT | Operations of computing devices are managed using one or more deep neural networks (DNNs), which may receive, as DNN inputs, data from sensors, instructions executed by processors, and/or outputs of other DNNs. One or more DNNs, which may be generative, can be applied to the DNN inputs to generate DNN outputs based on relationships between DNN inputs. The DNNs may include DNN parameters learned using one or more computing workloads. The DNN outputs may be, for example, control signals for managing operations of computing devices, predictions for use in generating control signals, warnings indicating an acceptable state is predicted, and/or inputs to one or more neural networks. The signals enhance performance, efficiency, and/or security of one or more of the computing devices. DNNs can be dynamically trained to personalize operations by updating DNN weights or other parameters. |
| FILED | Friday, June 16, 2017 |
| APPL NO | 15/625578 |
| ART UNIT | 2126 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 9/46 (20130101) G06F 9/50 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/063 (20130101) G06N 3/0445 (20130101) G06N 3/0454 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11328216 | Monroe et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Christopher Monroe (Ellicott City, Maryland); Martin Lichtman (Philadelphia, Pennsylvania); Ismail Volkan Inlek (Cary, North Carolina); Clayton Crocker (Hyattsville, Maryland); Ksenia Sosnova (Silver Spring, Maryland) |
| ABSTRACT | The disclosure describes aspects of using multiple species in trapped-ion nodes for quantum networking. In an aspect, a quantum networking node is described that includes multiple memory qubits, each memory qubit being based on a 171Yb+ atomic ion, and one or more communication qubits, each communication qubit being based on a 138Ba+ atomic ion. The memory and communication qubits are part of a lattice in an atomic ion trap. In another aspect, a quantum computing system having a modular optical architecture is described that includes multiple quantum networking nodes, each quantum networking node including multiple memory qubits (e.g., based on a 171Yb+ atomic ion) and one or more communication qubits (e.g., based on a 138Ba+ atomic ion). The memory and communication qubits are part of a lattice in an atomic ion trap. The system further includes a photonic entangler coupled to each of the multiple quantum networking nodes. |
| FILED | Friday, January 08, 2021 |
| APPL NO | 17/145116 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Electric Digital Data Processing G06F 9/3877 (20130101) G06F 9/5027 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 49/422 (20130101) Transmission H04B 10/70 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0858 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11328757 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Jian-Ping Wang (Shoreview, Minnesota); Protyush Sahu (Minneapolis, Minnesota) |
| ABSTRACT | In some examples, a device includes a dielectric material, a ferromagnetic material, and a topological material positioned between the dielectric material and the ferromagnetic material. The device is configured to trap electric charge inside the dielectric material or at an interface of the dielectric material and the topological material. The device is configured to switch a magnetization state of the ferromagnetic material based on a current through the topological material or based on a voltage in the topological material. |
| FILED | Friday, October 23, 2020 |
| APPL NO | 17/078764 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 11/161 (20130101) Original (OR) Class G11C 11/1675 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/222 (20130101) H01L 43/02 (20130101) H01L 43/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11328790 | Braun et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Rosemary Braun (Chicago, Illinois); Ravi Aliada (Glenview, Illinois); Phyllis Zee (Chicago, Illinois) |
| ABSTRACT | Provided herein are biomarkers of endogenous biological time (e.g. circadian time). In particular compositions and methods are provided for assessing the biological time of a subject, and diagnosis of diseases/conditions and/or providing treatments based thereon. |
| FILED | Tuesday, June 05, 2018 |
| APPL NO | 16/000607 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) C12Q 1/6883 (20130101) C12Q 2600/158 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) Original (OR) Class G16B 25/10 (20190201) G16B 40/20 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11328813 | Gordon et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF DEFENSE (Washington, District of Columbia); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia) |
| INVENTOR(S) | Chad Gordon (Cockeysville, Maryland); Mehran Armand (Fulton, Maryland); Ryan Murphy (Columbia, Maryland); Gerald Grant (Goshen, Kentucky); Peter Liacouras (North Potomac, Maryland); Kevin Wolfe (Lutherville, Maryland); Ehsan Basafa (Baltimore, Maryland) |
| ABSTRACT | A method for computer-assisted planning of a transplant surgery is provided. The method includes obtaining a computer-readable representation of a donor and recipient skeletal fragment; determining surgical cutting planes on the computer-readable representation of the donor skeletal fragment from which a portion of the donor skeletal fragment from the computer-readable representation of the donor skeletal fragment will be harvested; determining virtual cutting guides; performing a virtual osteotomy to separate the portion of the donor skeletal fragment from the computer-readable representation of the donor skeletal fragment from a remainder portion of the donor skeletal fragment based on a position of the virtual cutting guides that are attached to the computer-readable representation of the donor skeletal fragment; positioning the donor skeletal fragment within a transplant region of the recipient skeletal fragment; and creating a hybrid computer-readable representation comprising the recipient skeletal fragment and the portion of the donor skeletal. |
| FILED | Wednesday, October 14, 2020 |
| APPL NO | 17/070327 |
| ART UNIT | 2677 — Facsimile; Printer; Color; halftone; Scanner; Computer Graphic Processing; 3-D Animation; Display Color; Attributes; Object Processing; Hardware and Memory |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/15 (20130101) A61B 17/176 (20130101) A61B 17/1695 (20130101) A61B 17/1739 (20130101) A61B 17/8085 (20130101) A61B 34/10 (20160201) A61B 34/20 (20160201) A61B 2034/105 (20160201) A61B 2034/108 (20160201) A61B 2034/2051 (20160201) A61B 2034/2055 (20160201) A61B 2034/2065 (20160201) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2803 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/40 (20180101) G16H 30/40 (20180101) Original (OR) Class G16H 50/50 (20180101) Technologies for Adaptation to Climate Change Y02A 90/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11329211 | McCaughan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Adam N. McCaughan (Cambridge, Massachusetts); Karl K. Berggren (Arlington, Massachusetts); Qingyuan Zhao (Malden, Massachusetts) |
| ABSTRACT | An active three-terminal superconducting device having an intersection region at which a hot spot may be controllably formed is described. The intersection region may exhibit current crowding in response to imbalances in current densities applied to channels connected to intersection region. The current crowding may form a hot spot, in which the superconducting device may exhibit a measurable resistance. In some cases, a three-terminal superconducting device may be configured to sense an amount of superconducting current flowing in a channel or loop without having to perturb the superconducting state or amount of current flowing in the channel. A three-terminal superconducting device may be used to read out a number of fluxons stored in a superconducting memory element. |
| FILED | Thursday, August 13, 2020 |
| APPL NO | 16/992458 |
| ART UNIT | 2816 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 11/44 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/10 (20130101) Original (OR) Class H01L 39/145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11329311 | Zheng et al. |
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| FUNDED BY |
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| APPLICANT(S) | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida) |
| ASSIGNEE(S) | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida) |
| INVENTOR(S) | Jian-ping Zheng (Tallahassee, Florida); Chao Shen (Tallahassee, Florida) |
| ABSTRACT | A lithium-sulfur battery comprises a cathode electrode comprising from 80% to 100% lithium polysulfide based on the total weight of sulfur adsorbed at the cathode when the lithium sulfur battery is fully charged, and a high specific surface area electrically conductive material. An anode electrode comprises lithium. A porous and electrically insulating membrane is provided between the cathode and the anode electrodes. An electrolyte is adsorbed into and between cathode electrode, the anode electrode, and the membrane. A cathode current collector is electrically connected to the cathode and an anode current collector is electrically connected to the anode. A porous and electrically conductive interlayer can be provided between the membrane and at least one selected from the group consisting of the cathode and the anode. A method of making a battery is also disclosed. |
| FILED | Monday, November 19, 2018 |
| APPL NO | 16/194572 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/382 (20130101) H01M 4/625 (20130101) H01M 4/5815 (20130101) H01M 10/052 (20130101) Original (OR) Class H01M 10/058 (20130101) H01M 10/0566 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11329355 | Rinaldi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Matteo Rinaldi (Boston, Massachusetts); Giuseppe Michetti (Somerville, Massachusetts) |
| ABSTRACT | Adaptive RF filters based on modulated resonators are provided. The filter architecture is based on time-interleaved commutation of passive RF resonators. The architecture can behave as a two-port filter network, with a fully tunable instantaneous filter bandwidth. The filters are applicable as miniaturized, environment-aware RF signal processing components and can be used in mobile communications. |
| FILED | Wednesday, December 23, 2020 |
| APPL NO | 17/131964 |
| ART UNIT | 2843 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/2053 (20130101) Original (OR) Class H01P 7/06 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 9/542 (20130101) Transmission H04B 1/7093 (20130101) H04B 2001/70935 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11329446 | Gattass et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Rafael R. Gattass (Washington, District of Columbia); Colin C. Baker (Alexandria, Virginia); Augustus Xavier Carlson (Churchville, Maryland); L. Brandon Shaw (Woodbridge, Virginia); Jasbinder S. Sanghera (Ashburn, Virginia) |
| ABSTRACT | An apparatus includes an amplified spontaneous emission source, which in turn includes an optical fiber. The optical fiber includes a solid core and a first end. The solid core includes a silica matrix. The silica matrix includes a rare-earth element and a glass co-dopant. The rare-earth element includes dysprosium or neodymium. The glass co-dopant includes Al2O3. The apparatus further includes a laser pump diode coupled to the first end of the optical fiber. The laser pump diode and the optical fiber cooperate to generate a spontaneous spectral emission confined to the solid core. The spontaneous spectral emission includes a simultaneous plurality of spectral regions. |
| FILED | Wednesday, August 19, 2020 |
| APPL NO | 16/996975 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0941 (20130101) H01S 3/1606 (20130101) H01S 3/1611 (20130101) H01S 3/06712 (20130101) H01S 3/06716 (20130101) H01S 3/06795 (20130101) Original (OR) Class H01S 3/094003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11329689 | Rodenbeck |
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| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Christopher T. Rodenbeck (Annandale, Virginia) |
| ABSTRACT | Systems and method are provided for canceling unwanted transmitter-to-receiver leakage in a coherent wireless system using a feedforward waveform that overcomes the limitations of purely analog or purely digital cancelation systems and methods. Systems and methods in accordance with embodiments of the present disclosure generate a software-defined waveform that, when fed forward into the receiver, effectively cancels the leakage. Embodiments of the present disclosure can use a defined cancelation waveform (e.g., a software-defined cancelation waveform) that can cancel multiple leakage paths at the same time. |
| FILED | Wednesday, December 16, 2020 |
| APPL NO | 17/124077 |
| ART UNIT | 2641 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Transmission H04B 1/0003 (20130101) H04B 1/04 (20130101) H04B 1/30 (20130101) H04B 1/525 (20130101) Original (OR) Class H04B 1/7107 (20130101) H04B 2001/307 (20130101) H04B 2001/0408 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11330000 | Stavrou et al. |
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| FUNDED BY |
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| APPLICANT(S) | George Mason Research Foundation, Inc. (Fairfax, Virginia) |
| ASSIGNEE(S) | George Mason Research Foundation, Inc. (Fairfax, Virginia) |
| INVENTOR(S) | Angelos Stavrou (Springfield, Virginia); Sushil Jajodia (Oakton, Virginia); Anup K. Ghosh (Centreville, Virginia); Rhandi Martin (St. James, Barbados); Charalampos Andrianakis (Crete, Greece) |
| ABSTRACT | A transparent proxy for malware detection includes a monitor module, a protocol determination module, a challenge generation module, a response determination module, and a data control module. The monitor module examines data originating from an application towards a remote server. The protocol determination module identifies the protocol type used for the data. The challenge generation module produces a challenge for the application based upon the protocol type, sends the challenge to the application, and maintains a state related to the data and the challenge. The response determination module makes a determination if an automatic non-interactive application response is received in response to the challenge from the application. The data control module allows the first data to continue to the remote server when the determination is valid. The data control module reports malware detection and blocks the data to continue to the remote server when the determination is invalid. |
| FILED | Thursday, March 07, 2019 |
| APPL NO | 16/295498 |
| ART UNIT | 2439 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/566 (20130101) G06F 2221/2103 (20130101) G06F 2221/2119 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/08 (20130101) H04L 63/145 (20130101) H04L 63/0884 (20130101) H04L 63/1416 (20130101) Original (OR) Class H04L 67/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11330007 | Fong et al. |
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| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Alexander Fong (San Francisco, California); Xiaokui Shu (Ossining, New York); Marc Philippe Stoecklin (White Plains, New York) |
| ABSTRACT | An interactive display system enables a user to compose a graph pattern for a temporal graph on a display screen. The system comprises a canvas that provides an interactive editing surface. The editor receives an input a set of user interactions, such as the drawing of lines and boxes, the specifying of attributes, and the like, that together compose a graph pattern. During the graph pattern composition, the user may retrieve other graph patterns (e.g., from a data store) and integrate them into the pattern being composed. Once the graph pattern is composed (or as it is being composed), the system converts the graphical pattern into a text-based representation, such as a computer program in a particular graph programming language, which is then used for subsequent processing and matching in a cybersecurity threat discovery workflow. The pattern (program code) also is stored to disk, from which it may be retrieved and converted back into its graphical view on the screen, e.g., for further editing and revision. |
| FILED | Monday, December 23, 2019 |
| APPL NO | 16/725207 |
| ART UNIT | 2437 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1416 (20130101) H04L 63/1425 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11325070 | Smith et al. |
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| FUNDED BY |
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| APPLICANT(S) | PRECISION COMBUSTION INC. (North Haven, Connecticut) |
| ASSIGNEE(S) | Precision Combustion, Inc. (North Haven, Connecticut) |
| INVENTOR(S) | Warren F Smith (Enfield, Connecticut); Jeffrey G Weissman (Guilford, Connecticut); Prayush Singh (Mansfield, Connecticut) |
| ABSTRACT | A catalytic reactor constructed of a thermally conductive housing defining a reaction zone having disposed therein: (a) a plurality of catalytic elements, each comprising a porous material having a catalyst supported thereon, and (b) a plurality of heat transfer elements, each comprising a porous, thermally conductive, and essentially catalytically inactive material; wherein the plurality of catalytic elements and the plurality of heat transfer elements are disposed in an alternating configuration within the reaction zone. The catalytic reactor is useful in chemical reactions where heat transfer is a rate limiting step. |
| FILED | Friday, November 13, 2020 |
| APPL NO | 17/097016 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/864 (20130101) Original (OR) Class B01D 2255/904 (20130101) B01D 2255/9202 (20130101) B01D 2255/9205 (20130101) B01D 2257/502 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 35/04 (20130101) B01J 35/023 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/40 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325087 | Baxter |
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| FUNDED BY |
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| APPLICANT(S) | Sustainable Energy Solutions, Inc. (Provo, Utah) |
| ASSIGNEE(S) | Sustainable Energy Solutions, Inc. (Ball Ground, Georgia) |
| INVENTOR(S) | Larry Baxter (Orem, Utah) |
| ABSTRACT | A method, system, and device for separating components is described. A vessel is provided. A first volume of a process liquid, containing a first component and a second component, is passed into an inner chamber. The piston retracts to a first position. The fluid inlet is closed. The piston is retracted to a second position, causing the first component and a first portion of the second component to flash to form a vapor stream while a second portion of the second component freezes to form a solid product stream. The fluid outlet is then opened. The piston is advanced to a third position that results in a third volume, smaller than the first volume, such that the vapor stream is expelled. The fluid outlet is closed. The piston is fully closed such that the solid product stream is pressed into and extruded through the solids outlet. |
| FILED | Tuesday, April 02, 2019 |
| APPL NO | 16/372408 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 3/06 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 4/007 (20130101) B01J 4/008 (20130101) B01J 8/002 (20130101) Original (OR) Class B01J 8/0278 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325090 | Weissman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Precision Combustion, Inc. (North Haven, Connecticut) |
| ASSIGNEE(S) | Precision Combustion, Inc. (North Haven, Connecticut) |
| INVENTOR(S) | Jeffrey G Weissman (Guilford, Connecticut); Bruce Crowder (Hamden, Connecticut); Julian Prada (Philadelphia, Pennsylvania) |
| ABSTRACT | A catalytic solar reactor useful in chemical processes, more particularly, useful in endothermic chemical processes. The reactor comprises a reaction pathway defined by an exterior wall and an interior wall, the exterior wall comprising a solar radiation receiver capable of converting solar radiation into heat and transmitting the heat to the reaction pathway. Further, the reaction pathway has disposed therein, in alternating fashion, a plurality of catalytic elements and a plurality of heat transfer elements. Optionally, a supplementary heater, such as a conventional fossil fuel burner, is disposed in a plenum located within the interior of the reactor. The heater is employed as a supplemental source of heat, for example, when solar radiation is unavailable. |
| FILED | Friday, November 13, 2020 |
| APPL NO | 17/097048 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 12/007 (20130101) Original (OR) Class B01J 19/0013 (20130101) B01J 19/127 (20130101) B01J 19/2495 (20130101) B01J 2219/00076 (20130101) B01J 2219/00157 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/48 (20130101) C01B 3/384 (20130101) C01B 2203/062 (20130101) C01B 2203/0233 (20130101) C01B 2203/0238 (20130101) C01B 2203/0283 (20130101) C01B 2203/0811 (20130101) C01B 2203/0833 (20130101) C01B 2203/1241 (20130101) Acyclic or Carbocyclic Compounds C07C 1/041 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325112 | Matsui et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Research Foundation of the City University of New York (New York, New York) |
| ASSIGNEE(S) | Research Foundation of the City University of New York (New York, New York) |
| INVENTOR(S) | Hiroshi Matsui (Glen Rock, New Jersey); Zengyan Wei (Corona, New York); Justin Fang (New York, New York) |
| ABSTRACT | Nanocages are formed by etching nanocubes. The nanocubes are added to an aqueous system having an amphiphilic lipid dissolved in an organic solvent (e.g. a hydrophobic alcohol) to form reverse micelles. As the water evaporates the micelles shrink as etching of the flat surface of the nanocubes occurs. In this fashion hollow nanocages are produced. In one embodiment, the nanocage is covalently attached to a polymer shell (e.g. a dextran shell). |
| FILED | Monday, May 18, 2020 |
| APPL NO | 16/876206 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/1824 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/44 (20130101) B01J 23/52 (20130101) B01J 31/06 (20130101) B01J 31/28 (20130101) Original (OR) Class B01J 35/0013 (20130101) B01J 2231/4211 (20130101) B01J 2531/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325206 | Pawlowski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Alex E. Pawlowski (Oak Ridge, Tennessee); Amit Shyam (Knoxville, Tennessee); Derek A. Splitter (Knoxville, Tennessee); Amelia M. Elliott (Oak Ridge, Tennessee); Zachary C. Cordero (Houston, Texas) |
| ABSTRACT | A method for preparing metal/metal interpenetrating phase composites is provided. The method includes forming a preform using additive manufacturing. The preform defines a materially continuous three-dimensional open-cell mesh structure. The preform includes a first metal having a melting point. The method further includes pre-heating the preform to a first temperature less than the melting point of the first metal. The method includes infiltrating the preform with a second metal in liquid form. The second metal has a melting point lower than the melting point of the first metal. The method also includes allowing the second metal to cool and form a solid matrix. The solid matrix defines a continuous material network. |
| FILED | Friday, April 19, 2019 |
| APPL NO | 16/389280 |
| ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 19/00 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/11 (20130101) B22F 3/24 (20130101) B22F 3/26 (20130101) B22F 3/1115 (20130101) B22F 5/10 (20130101) B22F 7/002 (20130101) B22F 2007/045 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/34 (20130101) Original (OR) Class B23K 26/354 (20151001) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) Alloys C22C 1/0475 (20130101) C22C 21/00 (20130101) C22C 33/00 (20130101) C22C 33/0242 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325281 | Kunc et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Vlastimil Kunc (Knoxville, Tennessee); Craig A. Blue (Knoxville, Tennessee); Ahmed A. Hassen (Knoxville, Tennessee); John M. Lindahl (Knoxville, Tennessee); Lonnie J. Love (Knoxville, Tennessee); Brian K. Post (Knoxville, Tennessee) |
| ABSTRACT | A method for rapid manufacturing of three dimensional discontinuous fiber preforms is provided. The method includes the deposition of a polymeric material containing fibers on a surface to form a tailored charge for compression molding. The reinforced polymeric material may be a thermoplastic or a reactive polymer with viscosity low enough to allow flow through an orifice during deposition, yet high enough zero shear viscosity to retain the approximate shape of the deposited charge. The material can be deposited in a predetermined pattern to induce the desired mechanical properties through alignment of the fibers. This deposition can be performed in a single layer or in multiple layers. The alignment is achieved passively by shear alignment of the fibers or actively through fiber orientation control or mixing. The fibers can be of the desired material, length, and morphology, including short and long filaments. |
| FILED | Tuesday, July 23, 2019 |
| APPL NO | 16/519746 |
| ART UNIT | 1748 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 31/045 (20130101) B29C 31/085 (20130101) Original (OR) Class B29C 43/18 (20130101) B29C 43/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325348 | Aytug et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Tolga Aytug (Knoxville, Tennessee); Ilia N. Ivanov (Knoxville, Tennessee); Mina Yoon (Knoxville, Tennessee); Xiangtao Meng (Allentown, Pennsylvania); Soydan Ozcan (Oak Ridge, Tennessee) |
| ABSTRACT | A method for producing a carbon nanotube-metal composite in which carbon nanotubes are layered on a metal substrate, the method comprising: (i) depositing a liquid, in which carbon nanotubes are suspended, onto said metal substrate; (ii) during or after step (i), subjecting said liquid to a shearing force sufficient to spatially confine the liquid to induce at least partial alignment of said carbon nanotubes on said metal substrate; and (iii) removing said liquid to produce said carbon nanotube-metal composite; wherein, after step (iii), the lengthwise dimensions of said carbon nanotubes are adhered to and oriented parallel with said metal surface, and said carbon nanotubes are at least partially aligned with each other. In some embodiments, the liquid is deposited in the form of droplets, and the droplets are subjected to a shearing force to cause them to elongate, which induces at least partial alignment of the carbon nanotubes. |
| FILED | Tuesday, May 22, 2018 |
| APPL NO | 15/985785 |
| ART UNIT | 1717 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 9/007 (20130101) Original (OR) Class B32B 15/20 (20130101) B32B 2250/03 (20130101) B32B 2307/202 (20130101) B32B 2310/028 (20130101) B32B 2311/12 (20130101) B32B 2315/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/172 (20170801) C01B 32/174 (20170801) C01B 2202/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325873 | Ramasamy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington); LanzaTech, Inc. (Skokie, Illinois) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington); LanzaTech, Inc. (Skokie, Illinois) |
| INVENTOR(S) | Karthikeyan K. Ramasamy (West Richland, Washington); Mond Guo (Richland, Washington); Richard Russell Rosin (Glencoe, Illinois); Joseph Anthony Kocal (Glenview, Illinois) |
| ABSTRACT | Disclosed herein are embodiments of a method and system for converting ethanol to para-xylene. The method also provides a pathway to produce terephthalic acid from biomass-based feedstocks. In some embodiments, the disclosed method produces p-xylene with high selectivity over other aromatics typically produced in the conversion of ethanol to xylenes, such as m-xylene, ethyl benzene, benzene, toluene, and the like. And, in some embodiments, the method facilitates the ability to use ortho/para mixtures of methylbenzyaldehyde for preparing ortho/para xylene product mixtures that are amendable to fractionation to separate the para- and ortho-xylene products thereby providing a pure feedstock of para-xylene that can be used to form terephthalic anhydride and a pure feedstock of ortho-xylene that can be used for other purposes, such as phthalic anhydride. |
| FILED | Wednesday, July 28, 2021 |
| APPL NO | 17/387725 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 1/2076 (20130101) Original (OR) Class C07C 7/04 (20130101) C07C 45/68 (20130101) C07C 2521/04 (20130101) C07C 2521/06 (20130101) C07C 2521/18 (20130101) C07C 2523/44 (20130101) C07C 2523/656 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325991 | Mays et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
| ASSIGNEE(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
| INVENTOR(S) | Jimmy W. Mays (Knoxville, Tennessee); Wei Lu (Knoxville, Tennessee); Nam-Goo Kang (Knoxville, Tennessee) |
| ABSTRACT | Thermoplastic elastomer compositions comprising acrylic multigraft copolymers are described. The multigraft copolymers comprise a rubbery polyacrylate backbone and a plurality of randomly spaced glassy polyacrylate side chains. The multigraft copolymers can be prepared using a facile grafting through method that can provide copolymers with enhanced purity. The acrylic multigraft copolymers exhibit microphase separated morphologies and “superelastomeric” properties, including an elongation at break, stress at break, and/or strain recovery behavior that exceeds that of conventional triblock copolymer polyacrylate thermoplastic elastomers. |
| FILED | Wednesday, April 25, 2018 |
| APPL NO | 16/608614 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 2/38 (20130101) Original (OR) Class C08F 212/22 (20200201) C08F 212/26 (20200201) C08F 220/14 (20130101) C08F 220/1804 (20200201) C08F 220/1804 (20200201) C08F 290/046 (20130101) C08F 290/046 (20130101) C08F 2438/03 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 151/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326151 | Guss et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Adam M. Guss (Knoxville, Tennessee); Joshua R. Elmore (Richland, Washington); Jay D. Huenemann (Knoxville, Tennessee) |
| ABSTRACT | This disclosure provides a genetically-modified bacterium from the genus Pseudomonas that comprises an exogenous nucleic acid encoding an enoyl-CoA reductase and an exogenous nucleic acid encoding an acyl-CoA reductase that produces medium chain length alcohols. The disclosure further provides methods for producing medium chain alcohols using such genetically-modified bacterium. This disclosure provides a renewable, bio-based production platform for valuable mcl-alcohols that have a wide range of industrial applications. Current production of mcl-alcohols typically occurs through the hydrogenation of plant oils and waxes. This process leads to issues of deforestation and is largely unsustainable. Utilizing waste lignin streams as the carbon source provides a more sustainable feedstock that can be generated from plant waste like corn stover. Along with this, the use of lignin avoids competition with food resources as traditional starch and sugar feedstocks. |
| FILED | Tuesday, July 21, 2020 |
| APPL NO | 16/934570 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 1/205 (20210501) C12N 9/001 (20130101) C12N 9/0008 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/04 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/38 (20210501) C12R 2001/185 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326174 | Myers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Kevin S Myers (Madison, Wisconsin); Audrey P Gasch (Madison, Wisconsin) |
| ABSTRACT | The present invention relates to materials and methods for the production of ethanol. More particularly, the present invention provides genetically modified strains of Saccharomyces cerevisiae exhibiting decreased level of BCY1 protein activity and capable of anaerobic fermentation of xylose into ethanol without the need for cell growth. Also provided are methods of using such genetically engineered yeast strains for improved anaerobic xylose fermentation in the yeast for industrial-scale production of various fuels, chemical feedstocks, and synthetic polymers. |
| FILED | Friday, August 16, 2019 |
| APPL NO | 16/542758 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/81 (20130101) Original (OR) Class C12N 15/905 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326178 | Wilkerson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin); Board of Trustees of Michigan State University (East Lansing, Michigan); The Board of Trustees of Illinois State University (Normal, Illinois) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin); Board of Trustees of Michigan State University (East Lansing, Michigan); The Board of Trustees of Illinois State University (East Lansing, Michigan) |
| INVENTOR(S) | Curtis Wilkerson (Swartz Creek, Michigan); John Ralph (Madison, Wisconsin); Saunia Withers (Durham, North Carolina); John Sedbrook (Bloomington, Illinois) |
| ABSTRACT | The invention relates to nucleic acids encoding a p-coumaroyl-CoA:monolignol transferase and to inhibitory nucleic acids adapted to inhibit the expression and/or translation of a p-coumaroyl-CoA:monolignol transferase RNA. Inhibition of p-coumaroyl-CoA:monolignol transferase in plants improves the incorporation of monolignol ferulates into the lignin of plants, giving rise to plant biomass that is more easily processed into useful products such as paper and biofuels. |
| FILED | Wednesday, August 14, 2019 |
| APPL NO | 16/540979 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1029 (20130101) C12N 15/1137 (20130101) C12N 15/8218 (20130101) C12N 15/8255 (20130101) Original (OR) Class C12N 2310/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326190 | Beckham et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Gregg Tyler Beckham (Golden, Colorado); Christopher W. Johnson (Denver, Colorado); Derek R. Vardon (Lakewood, Colorado) |
| ABSTRACT | An aspect of the present disclosure is a microbial cell that includes a genetic modification resulting in the expression of a deficient form of an endogenous dioxygenase, and a gene encoding an exogenous dioxygenase and a promoter sequence, where the endogenous dioxygenase includes PcaH and PcaG, the exogenous dioxygenase includes LigA and LigB, the microbial cell is capable of growth utilizing at least one of a cellulose decomposition molecule or a lignin decomposition molecule, and the microbial cell is capable of producing 2-hydroxy-2H-pyran-4,6-dicarboxylic acid. |
| FILED | Thursday, January 31, 2019 |
| APPL NO | 16/263867 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) C12N 9/0008 (20130101) C12N 9/13 (20130101) C12N 9/18 (20130101) C12N 9/0069 (20130101) C12N 9/88 (20130101) C12N 9/90 (20130101) C12N 15/52 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/44 (20130101) Original (OR) Class C12P 17/06 (20130101) Enzymes C12Y 101/01312 (20130101) C12Y 102/01085 (20150701) C12Y 113/11001 (20130101) C12Y 113/11003 (20130101) C12Y 113/11008 (20130101) C12Y 208/03006 (20130101) C12Y 301/01024 (20130101) C12Y 301/01057 (20130101) C12Y 307/01009 (20130101) C12Y 401/01044 (20130101) C12Y 401/01045 (20130101) C12Y 401/01077 (20130101) C12Y 402/01083 (20130101) C12Y 503/02 (20130101) C12Y 503/02006 (20150701) C12Y 503/03004 (20130101) C12Y 505/01001 (20130101) C12Y 505/01002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326191 | Steen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LYGOS, INC. (Berkeley, California) |
| ASSIGNEE(S) | Lygos, Inc. (Berkeley, California) |
| INVENTOR(S) | Eric Steen (Berkeley, California); Jeffrey Dietrich (Berkeley, California); Johan Van Walsem (Berkeley, California) |
| ABSTRACT | A process for the preparation of bio-based malonic acid and crystalline calcium malonate is provided. The calcium malonate is highly pure and provides a source of malonic acid made from a renewable carbon source rather than existing processes which rely on the use of petroleum-based products. The calcium malonate provides an improved source of malonic acid, which is important to many industrial processes. |
| FILED | Tuesday, November 14, 2017 |
| APPL NO | 16/349948 |
| ART UNIT | 1699 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 63/02 (20130101) C07B 2200/13 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/02 (20130101) C12N 1/16 (20130101) C12N 1/165 (20210501) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/46 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/84 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326193 | Davis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Ryan Wesley Davis (San Jose, California); Fang Liu (Pleasanton, California) |
| ABSTRACT | The present invention relates to methods of providing a biomass residuum and compositions thereof. In particular examples, the biomass residuum includes one or more high value amino acids, even after removal of mixed alcohol components. In particular, the methods include implementing pre-treatment conditions and employing fermentation conditions including modified organisms. |
| FILED | Thursday, April 18, 2019 |
| APPL NO | 16/388385 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/81 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 13/06 (20130101) C12P 13/08 (20130101) Original (OR) Class C12P 13/20 (20130101) C12P 13/24 (20130101) C12P 13/225 (20130101) Enzymes C12Y 101/01001 (20130101) C12Y 101/01086 (20130101) C12Y 202/01006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326255 | Mane et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UChicago Argonne LLC (Argonne, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Anil U. Mane (Downers Grove, Illinois); Joseph Libera (Clarendon Hills, Illinois); Jeffrey W. Elam (Elmhurst, Illinois) |
| ABSTRACT | A system and method for improved atomic layer deposition. The system includes a top showerhead plate, a substrate and a bottom showerhead plate. The substrate includes a porous microchannel plate and a substrate holder is positioned in the system to insure flow-through of the gas precursor. |
| FILED | Friday, February 07, 2014 |
| APPL NO | 14/175396 |
| ART UNIT | 1716 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 38/0096 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/045 (20130101) C23C 16/45544 (20130101) C23C 16/45565 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 43/246 (20130101) H01J 2231/5016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326265 | Kenney et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| INVENTOR(S) | Michael J. Kenney (Stanford, California); Hongjie Dai (Stanford, California); Yun Kuang (Stanford, California); Yongtao Meng (Stanford, California) |
| ABSTRACT | A corrosion resistant anode is provided for oxygen evolution reaction in water including chloride ions. The anode includes: (1) a substrate; (2) a passivation layer coating the substrate; and (3) an electrocatalyst layer coating the passivation layer. Polyanion adjusted alkaline seawater electrolyte for hydrogen generation by electrolysis is also provided. |
| FILED | Friday, February 01, 2019 |
| APPL NO | 16/968813 |
| ART UNIT | 1759 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 11/03 (20130101) C25B 11/051 (20210101) Original (OR) Class C25B 11/052 (20210101) C25B 11/057 (20210101) C25B 11/075 (20210101) C25B 11/091 (20210101) C25B 15/08 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 11/34 (20130101) C25D 11/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326574 | Wilson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Michigan Technological University (Houghton, Michigan) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Michigan Technological University (Houghton, Michigan) |
| INVENTOR(S) | David G. Wilson (Tijeras, New Mexico); Giorgio Bacelli (Albuquerque, New Mexico); Ryan Geoffrey Coe (Albuquerque, New Mexico); Rush D. Robinett, III (Tijeras, New Mexico); Ossama Abdelkhalik (Ames, Iowa) |
| ABSTRACT | Increased energy harvesting is realized using a nonlinear buoy geometry for reactive power generation. By exploiting the nonlinear dynamic coupling between the buoy geometry and the potential wideband frequency spectrum of incoming waves in the controller/buoy design, increased power can be captured in comparison to conventional wave energy converter designs. In particular, the reactive power and energy storage system requirements are inherently embedded in the nonlinear buoy geometry, therefore requiring only simple rate-feedback control. |
| FILED | Monday, February 17, 2020 |
| APPL NO | 16/792749 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 22/00 (20130101) Machines or Engines for Liquids F03B 13/1885 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326790 | Woods et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Jason David Woods (Boulder, Colorado); Eric Kozubal (Superior, Colorado) |
| ABSTRACT | Integrated systems comprising both i) heat and mass exchange systems and ii) electrolysis stacks are disclosed, together with related methods of use. The disclosed systems cool and/or dehumidify air using two streams of salt solutions as liquid desiccants. |
| FILED | Wednesday, June 10, 2020 |
| APPL NO | 16/898227 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 3/1417 (20130101) Original (OR) Class F24F 13/30 (20130101) F24F 2003/1435 (20130101) F24F 2003/1458 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326810 | Ho |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Clifford K. Ho (Albuquerque, New Mexico) |
| ABSTRACT | Falling particle solar receivers, systems, and methods are disclosed that include one non-linear falling particle curtain or two or more falling particle curtains within a solar receiver that receives incident solar radiation. The particles heated in the solar receiver may be used to heat a secondary fluid. In an embodiment, the particles may be recirculated to improve energy capture and thermal efficiency. In other embodiments, an air curtain may be used across the aperture of the receiver, and flow-control devices may be used to evenly spread particles across the width of the receiver inlet. Finally, feed particles may be preheated using heat from the solar receiver. |
| FILED | Monday, December 02, 2019 |
| APPL NO | 16/700134 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Solar Heat Collectors; Solar Heat Systems F24S 10/90 (20180501) F24S 10/95 (20180501) F24S 21/00 (20180501) F24S 80/20 (20180501) Original (OR) Class F24S 90/00 (20180501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11327036 | Iftime et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Gabriel Iftime (Dublin, California); Clinton Smith (San Francisco, California); David Eric Schwartz (San Carlos, California); Yong Zhang (Millbrae, California); Vedasri Vedharathinam (Sunnyvale, California) |
| ABSTRACT | Disclosed herein are embodiments of compositions for gas sensing and sensors utilizing the same. In one embodiment, a composition comprises carbon nanotubes and polymer-coated metal nanoparticles bound to the carbon nanotubes. |
| FILED | Tuesday, August 18, 2020 |
| APPL NO | 16/996239 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/205 (20130101) B01J 20/0225 (20130101) B01J 20/327 (20130101) B01J 20/3204 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/054 (20220101) B22F 1/054 (20220101) B22F 1/054 (20220101) B22F 1/102 (20220101) B22F 1/102 (20220101) B22F 9/24 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Alloys C22C 2026/002 (20130101) C22C 2026/002 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/04 (20130101) Original (OR) Class G01N 27/126 (20130101) G01N 27/127 (20130101) G01N 33/0009 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11327123 | Cintuglu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hitachi Energy Switzerland AG (Baden, Switzerland) |
| ASSIGNEE(S) | Hitachi Energy Switzerland AG (Baden, Switzerland) |
| INVENTOR(S) | Mehmet H. Cintuglu (Raleigh, North Carolina); Dmitry Ishchenko (Cary, North Carolina) |
| ABSTRACT | A method includes detecting a fault in a grid coupled to a distribution power network, the distribution power network comprising a distribution feeder, a plurality of distributed energy resources (DERs) coupled to the distribution feeder and a reference point of applicability (RPA) associated with the plurality of DERs, and in response to detecting the fault, determining an error voltage at the RPA, converting the error voltage into an error signal, broadcasting the error signal to the plurality of DERs, and based on the error signal, reducing the error voltage at the RPA by injecting a plurality of currents from the plurality of DERs to the distribution feeder. |
| FILED | Monday, September 28, 2020 |
| APPL NO | 17/034912 |
| ART UNIT | 2868 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/40 (20130101) Original (OR) Class Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/001 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11327940 | Jacob et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Philip Jacob (Congers, New York); Philip Neil Strenski (Yorktown Heights, New York); Charles Johns (Austin, Texas) |
| ABSTRACT | A system and method for supporting tuple record interlinking in one or more tuple space/coordinated namespace (CNS) extended memory storage systems. A system-wide CNS provides for efficient storing and communicating of data generated by local processes running at the nodes, and coordinated to generate a union/intersection of multiple CNS where tuple records are interlinked in multiple CNS hashtables, and/or share tuple data between two sets of processes that are part of different CNSs. Local node processes further generate multi-key tuples where two or more tuple records are interlinked within the same CNS hash table, thereby permitting a look up of the tuple data by either tuple name/keys. A CNS controller further provides a tuple iterator for a key-value storage in a CNS system that adds more links between tuples enables creation of iterator structures such as linked list or trees etc. of “different” tuples in a tuple database. |
| FILED | Wednesday, December 18, 2019 |
| APPL NO | 16/719340 |
| ART UNIT | 2162 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 9/546 (20130101) G06F 9/3877 (20130101) G06F 16/2246 (20190101) G06F 16/2255 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11329209 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Zhong Chen (Fayetteville, Arkansas); Shui-Qing Yu (Fayetteville, Arkansas); H. Alan Mantooth (Fayetteville, Arkansas); Andrea Wallace (Fayetteville, Arkansas); Syam Madhusoodhanan (Fayetteville, Arkansas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhong Chen (Fayetteville, Arkansas); Shui-Qing Yu (Fayetteville, Arkansas); H. Alan Mantooth (Fayetteville, Arkansas); Andrea Wallace (Fayetteville, Arkansas); Syam Madhusoodhanan (Fayetteville, Arkansas) |
| ABSTRACT | A high temperature optoelectronic isolator for power electronics operating above 250 degrees Celcius. |
| FILED | Tuesday, December 17, 2019 |
| APPL NO | 16/717065 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/007 (20130101) H01L 33/641 (20130101) Original (OR) Class H01L 33/642 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11329241 | Forrest et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Stephen R. Forrest (Ann Arbor, Michigan); Byeongseop Song (Ann Arbor, Michigan); Jeramy D. Zimmerman (Golden, Colorado) |
| ABSTRACT | Disclosed herein are exciton-blocking treatments for buffer layers used in organic photosensitive optoelectronic devices. More specifically, the organic photosensitive optoelectronic devices described herein include at least one self-assembled monolayer disposed on the surface of an anode buffer layer. Methods of preparing these devices are also disclosed. The present disclosure further relates to methods of forming at least one self-assembled monolayer on a substrate. |
| FILED | Friday, August 29, 2014 |
| APPL NO | 14/912756 |
| ART UNIT | 2894 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0007 (20130101) H01L 51/424 (20130101) H01L 51/448 (20130101) H01L 51/4246 (20130101) H01L 51/4273 (20130101) Original (OR) Class H01L 2251/303 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11329244 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Jian Li (Tempe, Arizona); Tyler Fleetham (Gilbert, Arizona) |
| ABSTRACT | A light emitting device includes a first electrode, a hole transporting layer in contact with the first electrode, a second electrode, an electron transporting layer in contact with the second electrode; and an emissive layer between the hole transporting layer and the electron transporting layer. The emissive layer includes a phosphorescent emitter, a fluorescent emitter, and a host, and the phosphorescent emitter harvests electrogenerated excitons and transfers energy to the fluorescent emitter. |
| FILED | Friday, August 21, 2015 |
| APPL NO | 15/505527 |
| ART UNIT | 1786 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/185 (20130101) C09K 2211/1011 (20130101) C09K 2211/1029 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0059 (20130101) H01L 51/0072 (20130101) H01L 51/508 (20130101) H01L 51/5012 (20130101) H01L 51/5016 (20130101) H01L 51/5028 (20130101) H01L 51/5064 (20130101) Original (OR) Class H01L 51/5088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11329304 | Helms et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Brett A. Helms (San Francisco, California); Sean E. Doris (San Francisco, California); Ashleigh L. Ward (Berkeley, California); Peter D. Frischmann (Berkeley, California); Etienne Chenard (Urbanna, Illinois); Nagarjuna Gavvalapalli (Urbanna, Illinois); Jeffrey S. Moore (Savoy, Illinois) |
| ABSTRACT | Intermittent energy sources, including solar and wind, require scalable, low-cost, multi-hour energy storage solutions to be effectively incorporated into the grid. Redox-flow batteries offer a solution, but suffer from rapid capacity fade and low Coulombic efficiency due to the high permeability of redox-active species across the battery's membrane. Here we show that active-species crossover can be arrested by scaling the membrane's pore size to molecular dimensions and in turn increasing the size of the active material to be above the membrane's pore-size exclusion limit. When oligomeric redox-active organic molecules were paired with microporous polymer membranes, the rate of active-material crossover was either completely blocked or slowed more than 9,000-fold compared to traditional separators at minimal cost to ionic conductivity. In the case of the latter, this corresponds to an absolute rate of ROM crossover of less than 3 μmol cm−2 day−1 (for a 1.0 M concentration gradient), which exceeds performance targets recently set forth by the battery industry. This strategy was generalizable to both high and low-potential ROMs in a variety of electrolytes, highlighting the importance of macromolecular design in implementing next-generation redox-flow batteries. |
| FILED | Friday, May 26, 2017 |
| APPL NO | 15/606961 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/188 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11329806 | Akkaya et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kemal Akkaya (Miami, Florida); Mumin Cebe (Miami, Florida) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida) |
| INVENTOR(S) | Kemal Akkaya (Miami, Florida); Mumin Cebe (Miami, Florida) |
| ABSTRACT | Systems and methods for authentication and key agreement are provided and can utilize a scheme that uses dynamic key generation to achieve replay-attack resistance in zero round trip time (0-RTT). The hash-chain concept can be integrated with the Diffie-Hellman (DH) key exchange scheme. With this scheme, a device can securely determine the new shared key immediately (i.e., in 0-RTT) and start using it. |
| FILED | Wednesday, November 10, 2021 |
| APPL NO | 17/454418 |
| ART UNIT | 2495 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0844 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11324837 | Mackiewicz |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Portland State University (Portland, Oregon) |
| ASSIGNEE(S) | Portland State University (Portland, Oregon) |
| INVENTOR(S) | Marilyn Mackiewicz (Portland, Oregon) |
| ABSTRACT | Disclosed herein are embodiments of nanoparticle composites that comprise covalently coupled stabilizing agent molecules that improve stability of the nanoparticle composites and allow for tight packing of lipids and/or membranes. The nanoparticle composites can further comprise inhibition inhibitors and/or lipid components that interact to form a hybrid lipid bilayer membrane around the nanoparticle core. The nanoparticle composites can be coupled to drugs, targeting moieties, and imaging moieties. The nanoparticle composites can be used for in vivo drug deliver, disease diagnosis/treatment, and imaging. |
| FILED | Monday, September 10, 2018 |
| APPL NO | 16/127013 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5115 (20130101) A61K 47/6911 (20170801) Original (OR) Class A61K 47/6923 (20170801) A61K 47/6929 (20170801) A61K 49/0084 (20130101) A61K 49/0093 (20130101) A61K 49/0428 (20130101) A61K 49/1812 (20130101) A61K 49/1824 (20130101) A61K 49/1839 (20130101) A61K 49/1845 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325343 | Kar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Swastik Kar (Belmont, Massachusetts); Ji Hao (Boston, Massachusetts); Daniel Rubin (Boston, Massachusetts); Yung Joon Jung (Lexington, Massachusetts) |
| ABSTRACT | Ion-doped two-dimensional nanomaterials are made by inducing electronic carriers (electrons and holes) in a two-dimensional material using a captured ion layer at the surface of the material. The captured ion layer is stabilized using a capping layer. The induction of electronic carriers works in atomically-thin two-dimensional materials, where it induces high carrier density of at least 1014 carriers/cm2. A variety of novel ion-doped nanomaterials and p-n junction-based nanoelectronic devices are made possible by the method. |
| FILED | Monday, September 11, 2017 |
| APPL NO | 16/484024 |
| ART UNIT | 2816 — Semiconductors/Memory |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/16 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/194 (20170801) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/068 (20130101) H01L 29/0673 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326054 | Chu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Qianli Chu (Grand Forks, North Dakota); Rahul Shahni (Grand Forks, North Dakota) |
| ASSIGNEE(S) | The University of North Dakota (Grand Forks, North Dakota) |
| INVENTOR(S) | Qianli Chu (Grand Forks, North Dakota); Rahul Shahni (Grand Forks, North Dakota) |
| ABSTRACT | A polymer includes a plurality of repeated polymerized units according to scheme (2): |
| FILED | Tuesday, August 25, 2020 |
| APPL NO | 17/001966 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/193 (20130101) C08G 63/199 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/22 (20130101) C08K 5/57 (20130101) Compositions of Macromolecular Compounds C08L 67/02 (20130101) Original (OR) Class C08L 2203/10 (20130101) C08L 2203/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326138 | Trinkle et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| ASSIGNEE(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| INVENTOR(S) | Christine Trinkle (Lexington, Kentucky); Ren Xu (Lexington, Kentucky); Soroosh Torabi (Lexington, Kentucky) |
| ABSTRACT | Provided herein is a tissue culture device and a method of forming a tissue culture device. The tissue culture device includes a microfluidic layer including at least one hydrophobic microchannel and a reservoir portion over the at least one hydrophobic microchannel, the reservoir portion including an opening aligned with the at least one hydrophobic microchannel. The method of forming a tissue culture device includes providing a microfluidic layer mold, a reservoir layer mold, and a removable lid mold, filling each of the molds with a device material, curing the device material within the molds, removing the cured device material from the molds to provide a microfluidic layer, a reservoir layer, and a removable lid, and bonding the microfluidic layer to the reservoir layer. A method of culturing tissue with the tissue culture device is also provided herein. |
| FILED | Tuesday, May 01, 2018 |
| APPL NO | 15/968262 |
| ART UNIT | 1799 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) Original (OR) Class C12M 23/20 (20130101) C12M 23/38 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0693 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326255 | Mane et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UChicago Argonne LLC (Argonne, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Anil U. Mane (Downers Grove, Illinois); Joseph Libera (Clarendon Hills, Illinois); Jeffrey W. Elam (Elmhurst, Illinois) |
| ABSTRACT | A system and method for improved atomic layer deposition. The system includes a top showerhead plate, a substrate and a bottom showerhead plate. The substrate includes a porous microchannel plate and a substrate holder is positioned in the system to insure flow-through of the gas precursor. |
| FILED | Friday, February 07, 2014 |
| APPL NO | 14/175396 |
| ART UNIT | 1716 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 38/0096 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/045 (20130101) C23C 16/45544 (20130101) C23C 16/45565 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 43/246 (20130101) H01J 2231/5016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326327 | Yu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Guihua Yu (Austin, Texas); Fei Zhao (Austin, Texas); Xingyi Zhou (Austin, Texas) |
| ABSTRACT | Disclosed herein are water harvesting networks. The harvesters allow extraction and collection of moisture from the atmosphere without requiring electrical energy inputs. |
| FILED | Friday, February 09, 2018 |
| APPL NO | 16/484848 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Separation B01D 5/006 (20130101) B01D 53/28 (20130101) B01D 53/261 (20130101) B01D 2253/202 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/265 (20130101) Installations or Methods for Obtaining, Collecting, or Distributing Water E03B 3/28 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326344 | Yu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VERCO DECKING, INC. (Phoenix, Arizona) |
| ASSIGNEE(S) | VERCO DECKING, INC. (Phoenix, Arizona) |
| INVENTOR(S) | Cheng Yu (Southlake, Texas); Jeffrey Reino Martin (Fremont, California); Richard B. Haws (Corinth, Texas) |
| ABSTRACT | Embodiments of the invention relate to structural panel systems, and in particular in-frame fluted panel systems. The in-frame fluted panel systems allow for improved strength and/or ductility within a reduced wall thickness by installing the fluted panels within the framing of the support members in various configurations. The in-frame fluted panel systems further allows for easier construction and lower costs than conventional systems that have fluted panels located outside of the support members. |
| FILED | Thursday, October 29, 2020 |
| APPL NO | 17/084189 |
| ART UNIT | 3633 — Static Structures, Supports and Furniture |
| CURRENT CPC | General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/08 (20130101) E04B 2/56 (20130101) Original (OR) Class Structural Elements; Building Materials E04C 2/322 (20130101) E04C 2/384 (20130101) Roof Coverings; Sky-lights; Gutters; Roof-working Tools E04D 3/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326870 | Izatt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Joseph Izatt (Durham, North Carolina); Ruobing Qian (Durham, North Carolina); Sina Farsiu (Durham, North Carolina); Kevin Zhou (Durham, North Carolina) |
| ABSTRACT | Systems and methods for imaging based on multiple cross-sectional images acquired at different angles are disclosed. According to an aspect, multiple cross-sectional images of an object are acquired at different angles. The method also includes registering the acquired cross-sectional images. Further, the method includes reconstructing an enhanced resolution image of the object based on the registered images. As a result of registering the images, a distortion map is generated that is coregistered with the high-resolution image. The method also includes displaying an image of the object based on the enhanced resolution image and the distortion map. |
| FILED | Tuesday, January 29, 2019 |
| APPL NO | 16/955754 |
| ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0066 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/0203 (20130101) G01B 9/02091 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/4795 (20130101) Image Data Processing or Generation, in General G06T 3/0068 (20130101) G06T 7/30 (20170101) G06T 7/37 (20170101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326946 | Brueck et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNM RAINFOREST INNOVATIONS (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven R. J. Brueck (Albuquerque, New Mexico); Payman Zarkesh-Ha (Albuquerque, New Mexico); Alexander Neumann (Albuquerque, New Mexico) |
| ABSTRACT | Provided is a spectral sensor array, including: a planar waveguide on a substrate; a chirped input coupling grating, wherein the chirped input coupling grating comprises a transverse chirp to provide a spectrally selective coupling of incident light into the planar waveguide; an output coupling grating; and an array of photodetectors arranged to receive the light coupled out of the waveguide. |
| FILED | Tuesday, May 22, 2018 |
| APPL NO | 16/605529 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/24 (20130101) Original (OR) Class G01J 3/0259 (20130101) G01J 3/2803 (20130101) Optical Elements, Systems, or Apparatus G02B 6/12009 (20130101) G02B 2006/12061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11327012 | Brueck et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNM RAINFOREST INNOVATIONS (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven R. J. Brueck (Albuquerque, New Mexico); Juan Jose Faria Briceno (Albuquerque, New Mexico); Ruichao Zhu (Albuquerque, New Mexico) |
| ABSTRACT | A system for measuring a periodic array of structures on a sample is provided. The system includes an optical source configured to produce an optical beam; an optical system configured to control the polarization of the optical beam and to focus the optical beam with a first NA1 on a sample surface and to sweep the angle of incidence across a range of angles with an approximately fixed focal position on a sample surface with a second NA2 wherein NA2>NA1; additional optical components configured to receive the optical beam reflected from the sample surface and to focus the reflected beam onto a detector; and a recording system to record the reflectivity of the sample surface as a function of the angle of incidence. |
| FILED | Monday, May 06, 2019 |
| APPL NO | 17/053585 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/02 (20130101) G01B 2210/56 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/47 (20130101) Original (OR) Class G01N 2021/4723 (20130101) G01N 2201/0636 (20130101) G01N 2201/06113 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/70616 (20130101) G03F 7/70625 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11327018 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Somin Eunice Lee (Ann Arbor, Michigan); Yunbo Liu (Ann Arbor, Michigan); Yipei Wang (Ann Arbor, Michigan) |
| ABSTRACT | An image reconstruction method includes capturing a reference image of the specimen and capturing a set of original images based on the reference image. The method includes generating a set of analyzed images based on the set of original images by determining an intensity distribution for each pixel of each original image of the set of original images and combining the intensity distribution at each pixel location across the set of original images into an intermediate image. The method includes, identifying an object in the intermediate image. In response to identifying the object in the intermediate image, determining an intensity value of the object in each original image of the set of original images and generating an improved image of the object based on the determined intensity value of the object. The method includes generating a final image including the improved image of the object and displaying the final image. |
| FILED | Friday, April 12, 2019 |
| APPL NO | 17/047124 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 21/6445 (20130101) G01N 21/6458 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 21/367 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11327022 | Zhang |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dongmao Zhang (Starkville, Mississippi) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dongmao Zhang (Starkville, Mississippi) |
| ABSTRACT | The present invention provides for a novel series of accessories for Raman and/or luminescence spectral acquisitions for many different applications and methods for making such accessories. The invention further provides sample holders that enhance sample handling ability and sample sensitivity, reduce fluorescence and Raman background, as well as sample size and consumption, and thereby improve resulting spectral analyses. |
| FILED | Saturday, February 24, 2018 |
| APPL NO | 16/488294 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/508 (20130101) B01L 2300/168 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) Original (OR) Class G01N 2021/0357 (20130101) G01N 2021/651 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11327330 | Piestun et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| INVENTOR(S) | Rafael Piestun (Boulder, Colorado); Haiyan Wang (Boulder, Colorado) |
| ABSTRACT | Various embodiments provide for the implementation of volumetric diffractive optics equivalent functionality via cascaded planar elements. To illustrate the principle, a design 3D diffractive optics and implement a two-layer continuous phase-only design on a single spatial light modulator (SLM) with a folded system. The system provides dynamic and efficient multiplexing capability. Numerical and experimental results show this approach improves system performance such as diffraction efficiency, spatial/spectral selectivity, and number of multiplexing functions relative to 2D devices while providing dynamic large space-bandwidth relative to current static volume diffractive optics. The limitations and capabilities of dynamic 3D diffractive optics are discussed. |
| FILED | Tuesday, June 04, 2019 |
| APPL NO | 16/431412 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/0012 (20130101) G02B 27/4205 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11327886 | Huang |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Jian Huang (Champaign, Illinois) |
| ABSTRACT | A memory device (or memory sub-system) includes one or more memory components having multiple blocks, the multiple blocks containing pages of data. A processing device is coupled to the one or more memory components. The processing device to execute firmware to: track write timestamps of the pages of data that have been marked as invalid; retain a storage state stored for each page marked as invalid, wherein invalid data of the marked pages remains accessible via the storage states; in response to a write timestamp of a page being beyond a retention time window, mark the page as expired, indicating that the page is an expired page; and reclaim the expired page for storage of new data during a garbage collection operation. |
| FILED | Thursday, July 09, 2020 |
| APPL NO | 16/946873 |
| ART UNIT | 2138 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 12/0253 (20130101) Original (OR) Class G06F 12/1009 (20130101) G06F 2212/1044 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11327967 | Papaemmanouil et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BRANDEIS UNIVERSITY (Waltham, Massachusetts) |
| ASSIGNEE(S) | Brandeis University (Waltham, Massachusetts) |
| INVENTOR(S) | Olga Papaemmanouil (Waltham, Massachusetts); Mitch Cherniack (Boston, Massachusetts); Zhan Li (Foster City, California) |
| ABSTRACT | In some embodiments, a system is provided, comprising: memory storing instructions that, when executed, cause a processor to: submit a first database query; receive a runtime to execute the first database query using a plan selected by a query optimizer; receive runtimes to execute the first database query using a plurality of test plans; determine, based on the runtimes, a metric indicative of the effectiveness of the query optimizer; and cause the metric indicative of the effectiveness of the query optimizer to be presented to a user. |
| FILED | Friday, June 01, 2018 |
| APPL NO | 16/617245 |
| ART UNIT | 2169 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/217 (20190101) G06F 16/24542 (20190101) Original (OR) Class G06F 16/24549 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11328206 | Chai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | SRI Inlernational (Menlo Park, California) |
| INVENTOR(S) | Sek M. Chai (Princeton, New Jersey); David C. Zhang (Belle Mead, New Jersey); Mohamed R. Amer (Brooklyn, New York); Timothy J. Shields (Houston, Texas); Aswin Nadamuni Raghavan (Princeton, New Jersey); Bhaskar Ramamurthy (Menlo Park, California) |
| ABSTRACT | Operations of computing devices are managed using one or more deep neural networks (DNNs), which may receive, as DNN inputs, data from sensors, instructions executed by processors, and/or outputs of other DNNs. One or more DNNs, which may be generative, can be applied to the DNN inputs to generate DNN outputs based on relationships between DNN inputs. The DNNs may include DNN parameters learned using one or more computing workloads. The DNN outputs may be, for example, control signals for managing operations of computing devices, predictions for use in generating control signals, warnings indicating an acceptable state is predicted, and/or inputs to one or more neural networks. The signals enhance performance, efficiency, and/or security of one or more of the computing devices. DNNs can be dynamically trained to personalize operations by updating DNN weights or other parameters. |
| FILED | Friday, June 16, 2017 |
| APPL NO | 15/625578 |
| ART UNIT | 2126 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 9/46 (20130101) G06F 9/50 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/063 (20130101) G06N 3/0445 (20130101) G06N 3/0454 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11328832 | Yushin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sila Nanotechnologies Inc. (Alameda, California); GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
| ASSIGNEE(S) | SILA NANOTECHNOLOGIES INC. (Alameda, California); GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
| INVENTOR(S) | Gleb Yushin (Atlanta, Georgia); James Benson (Atlanta, Georgia); Danni Lei (Atlanta, Georgia); Eugene Berdichevsky (Oakland, California) |
| ABSTRACT | A catalyst-free synthesis method for the formation of a metalorganic compound comprising a desired (first) metal may include, for example, selecting another (second) metal and an organic solvent, with the second metal being selected to (i) be more reactive with respect to the organic solvent than the first metal and (ii) form, upon exposure of the second metal to the organic solvent, a reaction by-product that is more soluble in the organic solvent than the metalorganic compound. An alloy comprising the first metal and the second metal may be first produced (e.g., formed or otherwise obtained) and then treated with the organic solvent in a liquid phase or a vapor phase to form a mixture comprising (i) the reaction by-product comprising the second metal and (ii) the metalorganic compound comprising the first metal. The metalorganic compound may then be separated from the mixture in the form of a solid. |
| FILED | Monday, June 11, 2018 |
| APPL NO | 16/005400 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 13/18 (20130101) Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 5/06 (20130101) C01F 7/30 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2004/03 (20130101) C01P 2004/16 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/62227 (20130101) C04B 35/62231 (20130101) C04B 35/62236 (20130101) C04B 35/62263 (20130101) C04B 35/62844 (20130101) C04B 35/62884 (20130101) C04B 2235/441 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/06 (20130101) C07F 5/069 (20130101) Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black; C09C 1/407 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 1/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/45525 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/023 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11328833 | Watkins et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | James Watkins (South Hadley, Massachusetts); Michael R. Beaulieu (Chicopee, Massachusetts); Nicholas R. Hendricks (South Deerfield, Massachusetts) |
| ABSTRACT | Aspects relate to patterned nanostructures having a feature size not including film thickness of below 5 microns. The patterned nanostructures are made up of nanoparticles having an average particle size of less than 100 nm. A nanoparticle composition, which, in some cases, includes a binder, is applied to a substrate. A patterned mold used in concert with electromagnetic radiation function to manipulate the nanoparticle composition in forming the patterned nanostructure. In some embodiments, the patterned mold nanoimprints a pattern onto the nanoparticle composition and the composition is cured through UV or thermal energy, Three-dimensional patterned nanostructures may be formed. A number of patterned nanostructure layers may be prepared and joined together. In some cases, a patterned nanostructure may be formed as a layer that is releasable from the substrate upon which it is initially formed. Such releasable layers may be arranged to form a three-dimensional patterned nanostructure for suitable applications. |
| FILED | Friday, September 24, 2021 |
| APPL NO | 17/485281 |
| ART UNIT | 1785 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Optical Elements, Systems, or Apparatus G02B 1/118 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/08 (20130101) Original (OR) Class H01B 3/10 (20130101) H01B 13/003 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0015 (20130101) H01L 51/442 (20130101) H01L 51/5209 (20130101) H01L 2251/5369 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/04 (20130101) H01M 4/0433 (20130101) H01M 6/40 (20130101) H01M 8/124 (20130101) H01M 8/1286 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/50 (20151101) Technical Subjects Covered by Former US Classification Y10T 428/24893 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11329212 | Merrell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nano Composite Products, Inc. (Orem, Utah) |
| ASSIGNEE(S) | Nano Composite Products, Inc. (Orem, Utah) |
| INVENTOR(S) | Aaron Jake Merrell (Orem, Utah); David T. Fullwood (Provo, Utah); Anton E. Bowden (Lindon, Utah); Taylor D. Remington (Provo, Utah) |
| ABSTRACT | In one general aspect, a composite foam comprises a non-layered mixture of a polymeric foam with a plurality of voids; and a plurality of conductive fillers disposed in the polymeric foam. The conductive fillers are disposed in an even manner from outer surface to outer surface. In some implementations, the conductive fillers are up to 25% by weight of the composite foam. In some implementations, the composite foam may be used as padding. In some implementations, the composite foam may be used as a strain gauge. |
| FILED | Monday, May 18, 2020 |
| APPL NO | 15/929713 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/16 (20130101) G01L 1/18 (20130101) G01L 1/20 (20130101) G01L 5/0052 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/37 (20130101) H01L 41/183 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 29/49117 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11329362 | Pano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Vasil Pano (Philadelphia, Pennsylvania); Ibrahim Tekin (Tuzla, Turkey); Baris Taskin (Philadelphia, Pennsylvania); Kapil R. Dandekar (Philadelphia, Pennsylvania); Yuqiao Liu (Narberth, Pennsylvania) |
| ABSTRACT | On-chip wireless links offer improved network performance due to long distance communication, additional bandwidth, and broadcasting capabilities of antennas. A Through-Silicon Via (TSV)-based antenna design called TSV_A establishes multi-band wireless communication through the silicon substrate medium with only a 3 dB loss over a 30 mm on-chip distance. Simulation results show an improvement in network latency up to ˜13% (average improvement of ˜7%), energy-delay improvements of ˜34% on average, and an improvement in throughput up to ˜34% (average improvement). |
| FILED | Wednesday, December 18, 2019 |
| APPL NO | 16/719536 |
| ART UNIT | 2887 — Optics |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/66 (20130101) H01L 2223/6616 (20130101) H01L 2223/6627 (20130101) H01L 2223/6677 (20130101) Antennas, i.e Radio Aerials H01Q 1/48 (20130101) H01Q 1/2283 (20130101) Original (OR) Class H01Q 9/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11329831 | Traynor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Patrick G. Traynor (Gainesville, Florida); Bradley G. Reaves (Raleigh, North Carolina); Logan E. Blue (Palm Bay, Florida) |
| ABSTRACT | Methods and apparatuses for providing cryptographic authentication within a voice channel are disclosed. The methods and apparatuses can provide cryptographic authentication solely within a voice channel or can use a combination of a voice channel and another data channel. A method for providing cryptographic authentication within a voice channel can operate between telephonic systems and be suitable for operating over G.711/PCMu, AMR and SPEEX™ codecs, and suitable for operating over mobile, PSTN, and VOIP networks. The method can include providing a modem that is codec agnostic and suitable for executing a TLS-based authentication protocol. The method can include using frequency-shift modulation within a frequency range of 300-3400 Hz. |
| FILED | Thursday, June 08, 2017 |
| APPL NO | 16/304412 |
| ART UNIT | 2494 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0825 (20130101) H04L 9/3066 (20130101) H04L 9/3242 (20130101) H04L 9/3268 (20130101) Original (OR) Class H04L 27/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11330699 | Engin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | San Diego State University Research Foundation (San Diego, California); Kyocera International, Inc. (San Diego, California); Fraunhofer-Gesellschaft (Munich, Germany) |
| ASSIGNEE(S) | San Diego State University Research Foundation (San Diego, California); Kyocera International, Inc. (San Diego, California); Fraunhofer-Gesellschaft zur Foerderung der angewandten Forschung e.V. (Munich, Germany) |
| INVENTOR(S) | Arif Ege Engin (San Diego, California); Gerardo Aguirre (San Diego, California); Klaus-Dieter Lang (Berlin, Germany); Ivan Ndip (Berlin, Germany) |
| ABSTRACT | Embodiments described herein are directed to methods and apparatus for power distribution. The apparatus can include a power distribution network for a plurality of integrated circuits (IC). According to embodiments, the power distribution network includes a plurality of overlapping power/ground (PG) plane segments and one or more non-overlapping PG (no-PG) plane segments. Each overlapping-PG plane segment is separated from another overlapping-PG plane segment by at least one no-PG plane segment. The no-PG plane segments can include at least one of a multilayered power (P) plane segment with no ground reference of any PG plane and a multilayered ground (G) plane segment with no power reference of any PG plane. |
| FILED | Thursday, December 14, 2017 |
| APPL NO | 16/467895 |
| ART UNIT | 2847 — Electrical Circuits and Systems |
| CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0227 (20130101) Original (OR) Class H05K 2201/0792 (20130101) H05K 2201/09309 (20130101) H05K 2201/09345 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11325058 | Church et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Clinton D. Church (Julian, Pennsylvania); Ray B. Bryant (Spring Mills, Pennsylvania); Peter J. Kleinman (Warriors Mark, Pennsylvania); Alexander Nikolov Hristov (State College, Pennsylvania) |
| ABSTRACT | Apparatuses and methods to rejuvenate spent filtration media are described. The apparatuses include a filtration unit to filter a liquid having solids that need to be removed and a rejuvenation unit to heat the spent filtration media that has reduced filtering capacity. The methods include using the apparatus to rejuvenate spent filtration media by removing solids deposited on the filtration media to allow its repeated reuse rather than being discarded and replaced with new filtration media. |
| FILED | Thursday, August 22, 2019 |
| APPL NO | 16/548231 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 23/10 (20130101) B01D 24/4668 (20130101) Original (OR) Class B01D 2201/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11326191 | Steen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LYGOS, INC. (Berkeley, California) |
| ASSIGNEE(S) | Lygos, Inc. (Berkeley, California) |
| INVENTOR(S) | Eric Steen (Berkeley, California); Jeffrey Dietrich (Berkeley, California); Johan Van Walsem (Berkeley, California) |
| ABSTRACT | A process for the preparation of bio-based malonic acid and crystalline calcium malonate is provided. The calcium malonate is highly pure and provides a source of malonic acid made from a renewable carbon source rather than existing processes which rely on the use of petroleum-based products. The calcium malonate provides an improved source of malonic acid, which is important to many industrial processes. |
| FILED | Tuesday, November 14, 2017 |
| APPL NO | 16/349948 |
| ART UNIT | 1699 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 63/02 (20130101) C07B 2200/13 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/02 (20130101) C12N 1/16 (20130101) C12N 1/165 (20210501) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/46 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/84 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 11324612 | Hansen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Andrew H. Hansen (Apple Valley, Minnesota); Eric A. Nickel (Brooklyn Park, Minnesota); Billie Caris Savvas Slater (Mendota Heights, Minnesota); Stuart R. Fairhurst (Minneapolis, Minnesota); Jennifer Leestma (Wayzata, Minnesota) |
| ABSTRACT | A liner defines a pouch, an opening, a cup, and a first ring positioned on the pouch distal to the opening. The pouch is air-permeable and defines an internal volume for receiving a residual limb. The opening defined by the pouch provides access to the internal volume. The cup is air-impermeable and is positioned on the pouch distal to the opening. The liner is combined with an adapter for connecting a residual limb to a prosthetic limb. The adapter has a socket for receiving the cup, at least one hole positioned within the socket for drainage therefrom and sleeve extending from the socket and surrounding a central space. The adapter also has at least one vent positioned in the sleeve and overlies the air permeable material. |
| FILED | Friday, September 18, 2020 |
| APPL NO | 17/025008 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/60 (20130101) A61F 2/78 (20130101) A61F 2/80 (20130101) A61F 2/7812 (20130101) Original (OR) Class A61F 2002/802 (20130101) A61F 2002/805 (20130101) A61F 2002/807 (20130101) A61F 2002/7837 (20130101) A61F 2002/7893 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11324963 | Etkin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Amit Etkin (Stanford, California); Corey Keller (Palo Alto, California); Wei Wu (Palo Alto, California) |
| ABSTRACT | Provided herein are, for example, systems and methods of diagnosing and treating depression, in which a transcranial magnetic stimulation (TMS) therapy is administered to a subject in need thereof and measuring a TMS evoked response in the subject, are provided. The systems and methods allow tailoring or optimizing of a treatment protocol for maximal individual benefit, thereby providing an individualized and optimized treatment protocol for psychiatric disorders such as depression. |
| FILED | Wednesday, April 26, 2017 |
| APPL NO | 16/095661 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0075 (20130101) A61B 5/246 (20210101) A61B 5/369 (20210101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36025 (20130101) A61N 2/02 (20130101) A61N 2/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11325726 | Reth |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alan D Reth (Grasonville, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alan D Reth (Grasonville, Maryland) |
| ABSTRACT | A method and apparatus for estimating gyro scale factor during normal spacecraft operations, using small attitude motions that are compliant with mission pointing accuracy and stability requirements and a signal processing method that specifically detects the intentionally induced motions. This process increases operational availability by avoiding the need to take the spacecraft offline for large calibration maneuvers. |
| FILED | Tuesday, August 21, 2018 |
| APPL NO | 16/106070 |
| ART UNIT | 2862 — Printing/Measuring and Testing |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/288 (20130101) Original (OR) Class Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 25/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11325869 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Kang N. Lee (Westlake, Ohio); Deborah L. Waters (Brunswick, Ohio) |
| ABSTRACT | Slurry EBC systems and method for fabricating slurry EBC systems for protecting component substrates and extending the longevity of such components are disclosed. The slurry EBC systems include a bond coat having a temperature capability of up to 1482° C. (2700° F.). Example bond coats include a mullite-based bond coat and a rare earth disilicate-based bond coat. |
| FILED | Monday, October 22, 2018 |
| APPL NO | 16/166606 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 41/009 (20130101) C04B 41/52 (20130101) Original (OR) Class C04B 41/85 (20130101) C04B 41/89 (20130101) C04B 41/463 (20130101) C04B 41/4543 (20130101) C04B 41/5024 (20130101) C04B 41/5042 (20130101) C04B 41/5045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11324814 | Wu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Protein Potential, LLC (Rockville, Maryland) |
| ASSIGNEE(S) | Protein Potential, LLC (Rockville, Maryland) |
| INVENTOR(S) | Yun Wu (Rockville, Maryland); Dennis J. Kopecko (Silver Spring, Maryland); B. Kim Lee Sim (Gaithersburg, Maryland); Stephen L. Hoffman (Gaithersburg, Maryland) |
| ABSTRACT | Disclosed is the attenuated Salmonella typhi vaccine Ty21a utilized as a vector for Shigella and/or enterotoxogenic E. coli genes stably integrated in the Ty21a chromosome. These genes include a heterologous Shigella sonnei O-antigen biosynthetic gene region that comprises the wzz gene and expresses Shigella sonnei form 1 O-antigen, as well as a heterologous acid resistance biosynthetic gene system comprising a YbaS gene, which enables increased stability of the Ty21a vector at pH 2.5 relative to Ty21a without the integrated acid resistance biosynthetic gene system. |
| FILED | Wednesday, June 10, 2020 |
| APPL NO | 16/897999 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/116 (20130101) A61K 39/0275 (20130101) A61K 39/0283 (20130101) Original (OR) Class A61K 2039/70 (20130101) A61K 2039/522 (20130101) A61K 2039/523 (20130101) A61K 2039/543 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11329981 | Lewison et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Karen Pomian Lewison (Carmichael, California); Francisco Corella (Carmichael, California) |
| ASSIGNEE(S) | POMIAN and CORELLA, LLC (Sacramento, California) |
| INVENTOR(S) | Karen Pomian Lewison (Carmichael, California); Francisco Corella (Carmichael, California) |
| ABSTRACT | A method and system are provided for multifactor identification of a subject over a network using a rich credential, with selective disclosure of attributes and selective presentation of verification factors. A credential presentation application negotiates with a verifying server to agree on attributes to be disclosed and verification factors to be presented, and removes unneeded attributes and verification data from the rich credential by pruning subtrees from a typed hash tree without invalidating a signature that covers the root label of the tree. The credential presentation application proves knowledge of a private key, and as agreed upon may prove knowledge of a password and may arrange for biometric presentation applications to present one or more biometric samples to the verifier, which performs presentation attack detection and verifies the samples against verification data in the rich credential. |
| FILED | Saturday, January 04, 2020 |
| APPL NO | 16/734316 |
| ART UNIT | 2497 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3239 (20130101) H04L 9/3268 (20130101) H04L 63/083 (20130101) H04L 63/126 (20130101) H04L 63/205 (20130101) H04L 63/0823 (20130101) H04L 63/0861 (20130101) Original (OR) Class H04L 2463/082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 11324840 | Zabow et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by Secretary, Dept. of Health and Human Services (Bethesda, Maryland); The United States of America, as Represented by the Secretary of Commerce (Washington, District of Columbia) |
| ASSIGNEE(S) | THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland); THE USA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia) |
| INVENTOR(S) | Gary Zabow (Washington, District of Columbia); Stephen Dodd (Bethesda, Maryland); Alan Koretsky (Bethesda, Maryland); John Moreland (Washington, District of Columbia) |
| ABSTRACT | The present invention relates to a magnetic resonance structure with a cavity or a reserved space that provides contrast and the additional ability to frequency-shift the spectral signature of the NMR-susceptible nuclei such as water protons by a discrete and controllable characteristic frequency shift that is unique to each MRS design. The invention also relates to nearly uniform solid magnetic resonance T2* contrast agents that have a significantly higher magnetic moment compared to similarly-sized existing MRI contrast agents. |
| FILED | Monday, March 04, 2019 |
| APPL NO | 16/291731 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/0515 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/18 (20130101) A61K 49/1818 (20130101) A61K 49/1821 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 30/00 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/281 (20130101) G01R 33/563 (20130101) G01R 33/5601 (20130101) G01R 33/5635 (20130101) G01R 33/56325 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 11329981 | Lewison et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Karen Pomian Lewison (Carmichael, California); Francisco Corella (Carmichael, California) |
| ASSIGNEE(S) | POMIAN and CORELLA, LLC (Sacramento, California) |
| INVENTOR(S) | Karen Pomian Lewison (Carmichael, California); Francisco Corella (Carmichael, California) |
| ABSTRACT | A method and system are provided for multifactor identification of a subject over a network using a rich credential, with selective disclosure of attributes and selective presentation of verification factors. A credential presentation application negotiates with a verifying server to agree on attributes to be disclosed and verification factors to be presented, and removes unneeded attributes and verification data from the rich credential by pruning subtrees from a typed hash tree without invalidating a signature that covers the root label of the tree. The credential presentation application proves knowledge of a private key, and as agreed upon may prove knowledge of a password and may arrange for biometric presentation applications to present one or more biometric samples to the verifier, which performs presentation attack detection and verifies the samples against verification data in the rich credential. |
| FILED | Saturday, January 04, 2020 |
| APPL NO | 16/734316 |
| ART UNIT | 2497 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3239 (20130101) H04L 9/3268 (20130101) H04L 63/083 (20130101) H04L 63/126 (20130101) H04L 63/205 (20130101) H04L 63/0823 (20130101) H04L 63/0861 (20130101) Original (OR) Class H04L 2463/082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 11326476 | Tillman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HONEYWELL INTERNATIONAL INC. (Charlotte, North Carolina) |
| ASSIGNEE(S) | HONEYWELL INTERNATIONAL INC. (Charlotte, North Carolina) |
| INVENTOR(S) | Donald Tillman (Phoenix, Arizona); Ryon James Stanley (Phoenix, Arizona); Courtney Murphy (Phoenix, Arizona) |
| ABSTRACT | A system for coupling a shroud to a case associated with a gas turbine engine and a gas turbine engine including such a system includes the case defining a bore and the shroud retained within the case. The shroud defines a pocket. The system includes a pin received through the bore and at least partially positioned within the pocket. The pin has a perimeter. The system includes a load spreader including a first side and a second side opposite the first side. The first side is interconnected to the second side by a flexible portion. The first side, the second side and the flexible portion are received about a portion of the perimeter of the pin, and the load spreader is configured to transmit at least one of an axial point load and a circumferential point load from the pin over a surface of the shroud. |
| FILED | Thursday, October 22, 2020 |
| APPL NO | 17/077079 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/04 (20130101) F01D 11/005 (20130101) F01D 11/08 (20130101) F01D 11/18 (20130101) F01D 25/246 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/11 (20130101) F05D 2240/12 (20130101) F05D 2240/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 11327900 | Duncan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NVIDIA Corporation (Santa Clara, California) |
| ASSIGNEE(S) | NVIDIA Corporation (Santa Clara, California) |
| INVENTOR(S) | Samuel Hammond Duncan (Arlington, Massachusetts); Sanjeev Jain (Chandler, Arizona); Mark Douglas Hummel (Franklin, Massachusetts); Vyas Venkataraman (Sharon, Massachusetts); Olivier Giroux (Santa Clara, California); Larry Robert Dennison (Mendon, Massachusetts); Alexander Toichi Ishii (Lebanon, New Hampshire); Hemayet Hossain (San Jose, California); Nir Haim Arad (Snoqualmie, Washington) |
| ABSTRACT | Multiprocessor clusters in a virtualized environment conventionally fail to provide memory access security, which is frequently a requirement for efficient utilization in multi-client settings. Without adequate access security, a malicious process may access what might be confidential data that belongs to a different client sharing the multiprocessor cluster. Furthermore, an inadvertent programming error in the code for one client process may accidentally corrupt data that belongs to the different client. Neither scenario is acceptable. Embodiments of the present disclosure provide access security by enabling each processing node within a multiprocessor cluster to virtualize and manage local memory access and only process access requests possessing proper access credentials. In this way, different applications executing on a multiprocessor cluster may be isolated from each other while advantageously sharing the hardware resources of the multiprocessor cluster. |
| FILED | Thursday, July 23, 2020 |
| APPL NO | 16/937296 |
| ART UNIT | 2137 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 12/1027 (20130101) Original (OR) Class G06F 2212/68 (20130101) G06F 2212/1044 (20130101) G06F 2212/1052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 11324826 | Zamadar |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Matibur Rahaman Zamadar (Nacogdoches, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matibur Rahaman Zamadar (Nacogdoches, Texas) |
| ABSTRACT | Multifunctional compositions and methods are provided for therapeutic treatment of bacteria and cancers and for fluorescence diagnosis. Systems generate in situ reactive oxygen species such as singlet oxygen (1O2), hydroxyl radical (OH) and Juglone, and other chemotherapeutic agents. Methods provided selectively produce greater amounts of one reactive oxygen species over others. Variations are effective in aerobic, anaerobic or H2O2 rich environments and in presence of, or absence of, light. In H2O2 rich environment in absence of light, variations decompose H2O2 into O2 gas to remove excess H2O2 for elimination of hypoxic environment. Variations are formed of porphyrins, naphthalene derivatives, and metal ions, for illustration, free base tetrakis Ar substituted porphyrine core without metal or halide substitution but having hydroxyphenyl and alkyl pyridyl substituents at meso positions combined with dihydroxynaphthalene and +3 hydrated metal ions. |
| FILED | Monday, March 26, 2018 |
| APPL NO | 16/616437 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/045 (20130101) A61K 31/4439 (20130101) A61K 33/26 (20130101) A61K 41/0076 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 11326682 | Hundley, III et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Robert Lyell Hundley, III (Fairfax, Virginia); Terry Martin Gingell (Spotsylvania, Virginia) |
| ABSTRACT | Installation devices, systems, methods of use, and methods of manufacture are described. An installation device that facilitates installing a toothed belt on a sprocket within a housing. |
| FILED | Wednesday, May 05, 2021 |
| APPL NO | 17/308387 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Gearing F16H 57/00 (20130101) Original (OR) Class F16H 2057/0062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 11325951 | Poznansky et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Mark C. Poznansky (Newton Center, Massachusetts); Jeffrey A. Gelfand (Cambridge, Massachusetts) |
| ABSTRACT | This disclosure is directed to immune treatment of a disease (e.g., cancer) using a fusion protein in combination with an anti-chemorepellant agent. In particular, the fusion protein comprises an antigen-binding domain (e.g., an antibody or antibody fragment) and a stress protein domain. |
| FILED | Friday, September 08, 2017 |
| APPL NO | 16/331845 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/0019 (20130101) A61K 31/395 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/35 (20130101) Original (OR) Class C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 16/30 (20130101) C07K 2317/622 (20130101) C07K 2319/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11328794 | Green et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Richard E. Green (Santa Cruz, California); Samuel H. Vohr (Santa Cruz, California) |
| ABSTRACT | Disclosed are methods for testing biological samples containing genomic nucleic acids obtained from an organism having a genome, such as a human genome. It is often desirable to analyze a DNA sample or more than one, different DNA samples, to determine whether the sample comes from one individual or two individuals. The present method requires very low amounts of DNA and can use partial sequences of DNA fragments. Partial sequences are analyzed for the presence of polymorphisms (e.g. SNP's) that can be mapped to a reference SNP map. The distance between similar SNPS, which are genetically linked, can be used to statistically determine a likelihood of identity of individuality in a sample. |
| FILED | Wednesday, June 17, 2015 |
| APPL NO | 15/319253 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) G16B 20/20 (20190201) G16B 20/40 (20190201) G16B 30/00 (20190201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, May 10, 2022.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20220510.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page