FedInvent™ Patents

Patent Details for Tuesday, May 31, 2022

This page was updated on Thursday, June 02, 2022 at 06:15 AM GMT

Department of Health and Human Services (HHS)

11344025 — Organ preconditioning formulation with mitochondrial elongating agents

US 11344025	Nadig et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Institute of Allergy and Infectious Diseases (NIAID) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (Charleston, South Carolina)
ASSIGNEE(S)	MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (Charleston, South Carolina)
INVENTOR(S)	Satish N. Nadig (Johns Island, South Carolina); Carl Atkinson (Mt. Pleasant, South Carolina); Danh T. Tran (Charleston, South Carolina)
ABSTRACT	Provided herein is a formulation to pre-treat an organ prior to transplantation and for inducing mitochondrial morphological alterations.
FILED	Wednesday, December 26, 2018
APPL NO	16/339179
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0226 (20130101) Original (OR) Class Acyclic or Carbocyclic Compounds C07C 251/86 (20130101) Heterocyclic Compounds C07D 239/95 (20130101)
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11344180 — System, apparatus, and method for calibrating oblique-viewing rigid endoscope

US 11344180	Shekhar et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	CHILDREN'S NATIONAL MEDICAL CENTER (Washington, District of Columbia)
ASSIGNEE(S)	CHILDREN'S NATIONAL MEDICAL CENTER (Washington, District of Columbia)
INVENTOR(S)	Raj Shekhar (Washington, District of Columbia); Xinyang Liu (Washington, District of Columbia)
ABSTRACT	The present disclosure relates to an apparatus and method for correcting rotational error during use of an oblique-viewing endoscope. Specifically, the present disclosure relates to a fast calibration process wherein a new approach is employed in estimating a center of rotation of a plane of an image. Moreover, the approach, allows for updating of a camera matrix during use.
FILED	Friday, June 15, 2018
APPL NO	16/621917
ART UNIT	3795 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 1/05 (20130101) A61B 1/00057 (20130101) Original (OR) Class A61B 1/00179 (20130101) A61B 5/065 (20130101)
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11344199 — Systems and methods for detection and prediction of brain disorders based on neural network interaction

US 11344199	Li et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Aging (NIA)
APPLICANT(S)	Shi-Jiang Li (Brookfield, Wisconsin); Gang Chen (Wauwatosa, Wisconsin); Barney D. Ward (West Allis, Wisconsin); Zhilin Wu (Milwaukee, Wisconsin); Piero Antuono (Wauwatosa, Wisconsin)
ASSIGNEE(S)	The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin)
INVENTOR(S)	Shi-Jiang Li (Brookfield, Wisconsin); Gang Chen (Wauwatosa, Wisconsin); Barney D. Ward (West Allis, Wisconsin); Zhilin Wu (Milwaukee, Wisconsin); Piero Antuono (Wauwatosa, Wisconsin)
ABSTRACT	Systems and methods obtain functional connectivity data in the whole brain to detect and predict brain disorders. This whole brain data is regionalized and then manipulated to derive functional connectivity data sets that can be used to show measured functional connectivity changes. This whole brain data may also be analyzed to determine changes in functional activity in both increased and decreased neural network connectivity. By identifying and then quantifying the functional connectivity differences between healthy and diseased subjects, a classification for individual subjects can be made.
FILED	Tuesday, March 15, 2011
APPL NO	13/634284
ART UNIT	3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0042 (20130101) Original (OR) Class A61B 5/055 (20130101) A61B 5/4064 (20130101) A61B 5/4088 (20130101) A61B 5/7246 (20130101) A61B 5/7264 (20130101) A61B 5/7267 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4806 (20130101) Image Data Processing or Generation, in General G06T 7/0016 (20130101) G06T 2207/10016 (20130101) G06T 2207/10088 (20130101) G06T 2207/30016 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/70 (20180101)
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11344251 — Methods and apparatus for the assessment of gingival blood flow

US 11344251	Choi et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Bernard H. Choi (Irvine, California); Petra Wilder-Smith (Irvine, California); Bruce Y. Yang (Irvine, California); Caitlin Regan (Irvine, California); Sean M. White (Irvine, California); Tyler Rice (Irvine, California)
ABSTRACT	Disclosed herein are methods and apparatus for diagnosing a disease in the gingival region of an individual, comprising: quantitatively measuring blood flow or changes in blood flow in the gingival region of the individual, potentially comparing these data to that of a healthy subject, and diagnosing the disease based one of more of these quantities.
FILED	Friday, June 02, 2017
APPL NO	15/612889
ART UNIT	3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0088 (20130101) A61B 5/0261 (20130101) A61B 5/682 (20130101) A61B 5/4552 (20130101) Original (OR) Class A61B 5/4848 (20130101) A61B 5/7246 (20130101) Technologies for Adaptation to Climate Change Y02A 90/10 (20180101)
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11344463 — Delayed cord clamping system

US 11344463	Sherman et al.
FUNDED BY	Department of Health and Human Services (HHS) Agency for Healthcare Research and Quality (AHRQ)
APPLICANT(S)	Children's National Medical Center (Washington, District of Columbia)
ASSIGNEE(S)	Children's National Medical Center (Washington, District of Columbia)
INVENTOR(S)	Jules P. Sherman (Palo Alto, California); Douglas F. Schwandt (Palo Alto, California); Chris A. Rothe (San Mateo, California)
ABSTRACT	A delayed cord-clamping surface is provided that includes a newborn platform having a recessed surface configured to receive a chemical warming mattress, where the chemical warming mattress includes a conformable surface, where the newborn platform includes a detachable platform support that is configured to position the newborn platform proximal to a surgical region of a C-section patient, where the newborn platform is configured to support a newborn baby while an umbilical cord remains connected between the newborn and the C-section patient for draining from a placenta, where the newborn platform is configured to fitably mount with a warming table when the newborn platform is in a detached state from the detachable platform support.
FILED	Monday, February 25, 2019
APPL NO	16/284786
ART UNIT	3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices A61G 11/00 (20130101) A61G 13/12 (20130101) A61G 13/101 (20130101) A61G 13/105 (20130101) Original (OR) Class A61G 2210/90 (20130101)
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11344498 — Compositions and methods for on-demand high-efficiency triggerable anesthesia

US 11344498	Rwei et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	The Children's Medical Center Corporation (Boston, Massachusetts)
ASSIGNEE(S)	THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts)
INVENTOR(S)	Alina Y. Rwei (Brighton, Massachusetts); Changyou Zhan (Jamaica Plain, Massachusetts); Kathleen J. Cullion (Boston, Massachusetts); Daniel S. Kohane (Newton, Massachusetts)
ABSTRACT	Compositions and methods for administration of local anesthetics that are delivered by a single injection and enable repeated on-demand or high influx analgesia over extended periods have been developed. Pharmaceutical compositions including an effective amount of one or more sodium channel blockers including site 1 sodium channel blockers, optionally one or more alpha-2-adrenergic agonists, which are optionally encapsulated in liposomes, particles or microbubbles, and one or more triggerable elements are provided. The triggerable elements allow delivery of the encapsulated anesthetic drugs when an appropriate triggering stimuli are applied. Exemplary triggering agents or stimuli include near-infrared irradiation, UV- and visible light, ultrasound and magnetic field. In one embodiment, ultrasound is used to trigger a burst of microbubbles to enhance penetration of local anesthetic.
FILED	Friday, October 07, 2016
APPL NO	15/767116
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/1278 (20130101) Original (OR) Class A61K 31/445 (20130101) A61K 31/519 (20130101) A61K 31/519 (20130101) A61K 31/4174 (20130101) A61K 31/4174 (20130101) A61K 41/0028 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 23/02 (20180101)
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11344511 — Compounds and methods of promoting myelination

US 11344511	Tesar et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S)	Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S)	Paul Tesar (Wickliffe, Ohio); Drew Adams (Cleveland, Ohio); Zita Hubler (Cleveland, Ohio); Matthew Elitt (Shaker Heights, Ohio); Dharmaraja Allimuthu (Cleveland, Ohio); Steven B. Landau (Wellesley, Massachusetts)
ABSTRACT	A method of promoting the generation of oligodendrocytes from oligodendrocyte precursor cells by enhancing their survival and/or maturation includes administering to the cell an effective amount of an agent that enhances and/or induces accumulation of Δ8,9-unsaturated sterol intermediates of the cholesterol biosynthesis pathway in the oligodendrocyte precursor cells.
FILED	Thursday, July 27, 2017
APPL NO	16/320554
ART UNIT	1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/136 (20130101) A61K 31/137 (20130101) Original (OR) Class A61K 31/138 (20130101) A61K 31/198 (20130101) A61K 31/496 (20130101) A61K 31/4174 (20130101) A61K 31/4196 (20130101) A61K 31/4535 (20130101) A61K 31/4545 (20130101) A61K 31/5375 (20130101) A61K 31/7105 (20130101) A61K 38/16 (20130101) A61K 38/215 (20130101) A61K 39/3955 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/14 (20180101) A61P 25/28 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/50 (20130101) C12N 15/1137 (20130101)
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11344527 — Methods and compositions for treating cancer

US 11344527	McAllister et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Sutter West Bay Hospitals (San Francisco, California)
ASSIGNEE(S)	Sutter Bay Hospitals (San Francisco, California)
INVENTOR(S)	Sean D. McAllister (San Francisco, California); Pierre-Yves Desprez (Richmond, California)
ABSTRACT	This disclosure provides compositions and method useful for treating cell proliferative disorders including cancer. The disclosure provides cannabidiol derivatives and compositions thereof either alone or in combination with THC or a derivative thereof.
FILED	Friday, November 08, 2013
APPL NO	14/075848
ART UNIT	1629 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/05 (20130101) A61K 31/35 (20130101) A61K 31/352 (20130101) Original (OR) Class A61K 45/06 (20130101)
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11344534 — Cholinergic agonism for the treatment of pancreatic cancer

US 11344534	Wang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S)	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S)	Timothy C. Wang (New York, New York); Bernhard Renz (Germering, Germany)
ABSTRACT	The invention provides for methods for treating pancreatic cancer, reducing or inhibiting pancreatic tumor cells, inhibiting or treating pancreatic cancer metastases, and inhibiting pancreatic cancer stem cell growth in a subject by administering a cholinergic agonist.
FILED	Monday, December 23, 2019
APPL NO	16/725668
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/27 (20130101) A61K 31/337 (20130101) A61K 31/4178 (20130101) Original (OR) Class A61K 31/7068 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101)
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11344559 — PI3KGAMMA inhibitors

US 11344559	Varner et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Judith Varner (La Jolla, California); Rommie Amaro (La Jolla, California); Megan Kaneda (La Jolla, California); Robert Malmstrom (La Jolla, California); Victoria Feher (La Jolla, California)
ABSTRACT	The present disclosure relates to PI3Kγ inhibitors and methods of their use.
FILED	Thursday, June 25, 2020
APPL NO	16/911894
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/438 (20130101) A61K 31/444 (20130101) A61K 31/453 (20130101) A61K 31/551 (20130101) Original (OR) Class A61K 31/4196 (20130101)
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11344574 — Fluoro substituted porphyrin compounds, pharmaceutical compositions comprising the same, and methods of preparing and using the same

US 11344574	Batinic-Haberle et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Duke University (Durham, North Carolina)
ASSIGNEE(S)	Duke University (Durham, North Carolina)
INVENTOR(S)	Ines Batinic-Haberle (Durham, North Carolina); Artak Tovmasyan (Durham, North Carolina); Ivan Spasojevic (Durham, North Carolina)
ABSTRACT	Provided herein are fluoro-substituted porphyrin compounds, such as those having a structure represented by Formula (I), wherein R¹is a C1-C8 alkyl that is substituted with at least 1 fluorine (e.g., a C1-C8 alkyl substituted with 1-17 fluorine atoms); and X is an anion (e.g. a halogen ion (e.g., chloride, etc.), PF₆, tosylate, besylate, and/or mesylate). Also provided herein are methods of making the fluoro-substituted porphyrin compounds, pharmaceutical formulations containing the same, and methods of use thereof.
FILED	Wednesday, September 26, 2018
APPL NO	16/645907
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/375 (20130101) A61K 33/32 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 39/00 (20180101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 13/005 (20130101)
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11344577 — Car+ T cells genetically modified to eliminate expression of T-cell receptor and/or HLA

US 11344577	Cooper et al.
FUNDED BY	Department of Defense (DOD) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S)	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S)	Laurence J. Neil Cooper (Houston, Texas); Hiroki Torikai (Houston, Texas)
ABSTRACT	The present invention concerns methods and compositions for immunotherapy employing a modified T cell comprising disrupted T cell receptor and/or HLA and comprising a chimeric antigen receptor. In certain embodiments, the compositions are employed allogeneically as universal reagents for “off-the-shelf” treatment of medical conditions such as cancer, autoimmunity, and infection. In particular embodiments, the T cell receptor-negative and/or HLA-negative T cells are generated using zinc finger nucleases, for example.
FILED	Monday, July 08, 2019
APPL NO	16/504427
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 39/0011 (20130101) A61K 39/00111 (20180801) A61K 39/00117 (20180801) A61K 39/00119 (20180801) A61K 39/001104 (20180801) A61K 39/001106 (20180801) A61K 39/001109 (20180801) A61K 39/001112 (20180801) A61K 39/001117 (20180801) A61K 39/001119 (20180801) A61K 39/001124 (20180801) A61K 39/001129 (20180801) A61K 39/001151 (20180801) A61K 39/001164 (20180801) A61K 39/001171 (20180801) A61K 39/001174 (20180801) A61K 39/001181 (20180801) A61K 39/001182 (20180801) A61K 2039/5156 (20130101) A61K 2039/5158 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2510/00 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101)
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11344582 — Treating myelin diseases with optimized cell preparations

US 11344582	Goldman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	University of Rochester (Rochester, New York)
ASSIGNEE(S)	UNIVERSITY OF ROCHESTER (Rochester, New York)
INVENTOR(S)	Steven Goldman (Webster, New York); Fraser J. Sim (Buffalo, New York)
ABSTRACT	The disclosure relates to oligodendrocyte-biased glial progenitor cells and methods of making, isolating, and using such cells.
FILED	Friday, February 10, 2017
APPL NO	15/429629
ART UNIT	1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) A61K 35/30 (20130101) Original (OR) Class Peptides C07K 14/70596 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0622 (20130101) C12N 5/0623 (20130101) C12N 9/1276 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5058 (20130101)
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11344600 — Structure of GII.4 norovirus protease—design of broad-spectrum protease inhibitors

US 11344600	Prasad et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Baylor College of Medicine (Houston, Texas)
ASSIGNEE(S)	Baylor College of Medicine (Houston, Texas)
INVENTOR(S)	B. Venkataram Prasad (Houston, Texas); Mary K. Estes (Houston, Texas); Yongcheng Song (Pearland, Texas)
ABSTRACT	The present disclosure concerns inhibitors of Norovirus protease that are suitable for use against any genotype of Norovirus, including at least GII.4 Norovirus proteases. In particular embodiments, specific compositions are encompassed, including their use for prevention or treatment of Norovirus infection in an individual.
FILED	Thursday, October 05, 2017
APPL NO	16/335349
ART UNIT	1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/46 (20130101) A01N 43/64 (20130101) A01N 43/90 (20130101) A01N 47/12 (20130101) A01N 47/28 (20130101) A01N 47/34 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 31/27 (20130101) A61K 31/27 (20130101) A61K 31/40 (20130101) A61K 31/40 (20130101) A61K 31/395 (20130101) A61K 31/395 (20130101) A61K 31/407 (20130101) A61K 31/407 (20130101) A61K 38/00 (20130101) A61K 38/06 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Acyclic or Carbocyclic Compounds C07C 201/00 (20130101) C07C 271/18 (20130101) C07C 271/22 (20130101) Heterocyclic Compounds C07D 295/10 (20130101) C07D 498/08 (20130101) Peptides C07K 5/06017 (20130101) C07K 5/06026 (20130101) C07K 5/06052 (20130101) C07K 5/06086 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 15/30 (20190201) Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/50 (20190201)
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11344613 — Sequential administration of a replication defective adenovirus vector in vaccination protocols

US 11344613	Balint et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Etubics Corporation (Seattle, Washington)
ASSIGNEE(S)	Etubics Corporation (Seattle, Washington)
INVENTOR(S)	Joseph P. Balint (Seattle, Washington); Frank R. Jones (Ellensburg, Washington); Richard B. Gayle, III (Woodinville, Washington)
ABSTRACT	Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided.
FILED	Tuesday, September 18, 2012
APPL NO	13/622263
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/191 (20130101) A61K 38/193 (20130101) A61K 38/204 (20130101) A61K 38/208 (20130101) A61K 38/217 (20130101) A61K 38/2013 (20130101) A61K 38/2026 (20130101) A61K 38/2033 (20130101) A61K 38/2046 (20130101) A61K 38/2066 (20130101) A61K 39/00 (20130101) A61K 39/0011 (20130101) A61K 39/12 (20130101) Original (OR) Class A61K 39/21 (20130101) A61K 39/235 (20130101) A61K 39/001106 (20180801) A61K 39/001182 (20180801) A61K 2039/54 (20130101) A61K 2039/57 (20130101) A61K 2039/545 (20130101) A61K 2039/575 (20130101) A61K 2039/5256 (20130101) A61K 2039/55555 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/005 (20130101) C07K 14/71 (20130101) C07K 14/70503 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2710/10034 (20130101) C12N 2710/10321 (20130101) C12N 2710/10334 (20130101) C12N 2710/10343 (20130101) C12N 2710/10371 (20130101) C12N 2710/20034 (20130101) C12N 2740/15034 (20130101) C12N 2740/16234 (20130101) C12N 2800/24 (20130101)
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11344614 — Pharmaceutical compositions comprising dengue virus-specific multiple HLA-binding T cell epitopes

US 11344614	Philip
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Emergex Vaccines Holding Ltd. (Abingdon, United Kingdom)
ASSIGNEE(S)	Emergex Vaccines Holding Ltd. (Oxford, United Kingdom)
INVENTOR(S)	Ramila Philip (Ivyland, Pennsylvania)
ABSTRACT	Dengue Fever (DF) and Dengue Hemorrhagic Fever (DHF) are significant global public health problems and understanding the overall immune response to infection will contribute to appropriate management of the disease and its potentially severe complications. Live attenuated and subunit vaccine candidates, which are under clinical evaluation, induce primarily an antibody response to the virus and minimal cross-reactive T cell responses. Currently, there are no available tools to assess protective T cell responses during infection or post vaccination. Herein, we report novel, naturally processed and presented MHC class I restricted epitopes, a subset of which binds to and activates T cells in both an HLA-A2 and HLA-A24 restricted manner. We show that epitope specific T cells can be activated in vivo in transgenic mice and in vitro in seropositive and seronegative individuals and that these T cells are functional, recognizing peptide pulsed and dengue virus infected cells in a pro-inflammatory and cytotoxic manner. These epitopes have potential as new informational and diagnostic tools to characterize T cell immunity in Dengue virus (DV) infection, and may serve as a universal vaccine candidate complementary to current vaccines in trial.
FILED	Saturday, September 29, 2018
APPL NO	16/147637
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/1825 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2770/24111 (20130101) C12N 2770/24122 (20130101)
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11344615 — Nucleic acids encoding chimeric dengue/Zika viruses optimized for growth and stability in vero cells

US 11344615	Kinney
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S)	Claire Y. H. Kinney (Fort Collins, Colorado)
ABSTRACT	Chimeric flaviviruses that include non-coding regions, non-structural proteins, a capsid (C) protein and a portion of a premembrane (prM) signal sequence from an attenuated or wild-type dengue serotype 2 virus (DENV-2), and a portion of a prM signal sequence, a prM protein and at least a portion of an envelope (E) protein from a Zika virus (ZIKV) are described. Also described are immunogenic compositions and methods for eliciting an immune response in a subject, such as an immune response directed against ZIKV.
FILED	Thursday, July 06, 2017
APPL NO	16/316005
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/5252 (20130101) A61K 2039/5256 (20130101) Peptides C07K 14/005 (20130101) C07K 14/1816 (20130101) C07K 14/1825 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/24122 (20130101) C12N 2770/24134 (20130101) C12N 2770/24141 (20130101) C12N 2770/24144 (20130101)
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11344619 — Formulation containing TLR agonist and methods of use

US 11344619	Fox
FUNDED BY	Department of Health and Human Services (HHS) Assistant Secretary for Preparedness and Response (ASPR) Biomedical Advanced Research and Development Authority (BARDA)
APPLICANT(S)	ACCESS TO ADVANCED HEALTH INSTITUTE (Seattle, Washington)
ASSIGNEE(S)	ACCESS TO ADVANCED HEALTH INSTITUTE (Seattle, Washington)
INVENTOR(S)	Christopher B. Fox (Sumner, Washington)
ABSTRACT	Stable aqueous formulations of adjuvant comprising a TLR7/8 agonist or a TLR4 agonist with a helper lipid that are adsorbed to alum are provided. Compositions and methods of using the formulations for stimulating an immune response are also provided.
FILED	Thursday, May 11, 2017
APPL NO	16/098615
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/76 (20130101) A61K 39/04 (20130101) A61K 39/12 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2039/57 (20130101) A61K 2039/552 (20130101) A61K 2039/572 (20130101) A61K 2039/55505 (20130101) A61K 2039/55511 (20130101) A61K 2039/55572 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/06 (20180101) A61P 31/12 (20180101) A61P 33/04 (20180101) A61P 35/00 (20180101) Peptides C07K 14/705 (20130101) C07K 14/70596 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16134 (20130101)
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11344630 — Methods and compositions for red-shifted chromophore substitution for optogenetic applications

US 11344630	Corbo et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	Washington University (St. Louis, Missouri)
ASSIGNEE(S)	Washington University (St. Louis, Missouri)
INVENTOR(S)	Joseph Corbo (St. Louis, Missouri); Jennifer Enright (St. Louis, Missouri); Matthew Toomey (St. Louis, Missouri)
ABSTRACT	The present disclosure provides compositions and methods used for optogenetics, wherein the composition comprises an optogenetic device and a retinoid processing enzyme.
FILED	Monday, July 09, 2018
APPL NO	16/030785
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) Original (OR) Class Peptides C07K 14/405 (20130101) C07K 2319/00 (20130101) C07K 2319/50 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0008 (20130101) C12N 9/0071 (20130101) C12N 15/86 (20130101) C12N 2750/14143 (20130101) Enzymes C12Y 102/01036 (20130101)
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11344635 — Compounds for use as iron (III) MRI contrast agents containing anionic pendents and ancillary groups

US 11344635	Morrow et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	The Research Foundation for The State University of New York (Buffalo, New York)
ASSIGNEE(S)	The Research Foundation for the State University of New York (Amherst, New York)
INVENTOR(S)	Janet R. Morrow (Williamsville, New York); Zuiru Lin (Williamsville, New York); Didar Asik (Tonawanda, New York); Eric M. Snyder (Tonawanda, New York); Elizabeth A. Kras (Amherst, New York)
ABSTRACT	Macrocyclic complexes and macrocyclic compounds. The macrocyclic complexes or macrocyclic compounds have a TACN moiety with one or more amine group(s) or a O- or S-substituted TACN moiety. The macrocyclic complexes have a high-spin Fe(III) atom coordinated to the TACN moiety. The macrocyclic complexes can be used in imaging methods.
FILED	Monday, November 18, 2019
APPL NO	16/973349
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 49/106 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/6515 (20130101) C07F 15/025 (20130101)
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11344711 — Swellable adhesive needles

US 11344711	Yang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
ASSIGNEE(S)	The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S)	Seung Yun Yang (Allston, Massachusetts); Jeffrey M. Karp (Brookline, Massachusetts); Eoin D. O'Cearbhaill (Cambridge, Massachusetts); Bohdan Pomahac (Dover, Massachusetts)
ABSTRACT	This disclosure relates to swellable needles that include a proximal end portion and a swellable distal end portion. Upon exposure to a liquid, the needles are configured to undergo a shape change from a first configuration in which the width of the needle is tapered from the proximal end portion to the distal end portion to a second configuration in which the distal end portion is more swollen than the proximal end portion. The swellable needles can be double layer swellable needles or single material swellable needles.
FILED	Monday, September 23, 2019
APPL NO	16/579075
ART UNIT	3783 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC	Diagnosis; Surgery; Identification A61B 17/08 (20130101) A61B 17/064 (20130101) A61B 2017/0641 (20130101) A61B 2017/00893 (20130101) A61B 2017/00898 (20130101) A61B 2017/06176 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/0015 (20130101) Original (OR) Class A61M 2037/0023 (20130101) A61M 2037/0046 (20130101) A61M 2037/0053 (20130101) A61M 2037/0061 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 22/00 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 37/18 (20130101) B32B 37/142 (20130101) B32B 38/0012 (20130101) B32B 2535/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 156/1043 (20150115)
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11344719 — Electric bandage for accelerated wound recovery

US 11344719	Wang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Xudong Wang (Middleton, Wisconsin); Yin Long (Madison, Wisconsin); Weibo Cai (Madison, Wisconsin); Hao Wei (Madison, Wisconsin)
ABSTRACT	A wearable medical bandage is provided having an energy harvesting generator that harvests mechanical energy from the user's natural body and muscle motions to produce electrical energy. The electrical energy induces an electric potential across the wound opening producing accelerated skin wound recovery under the voltage fluctuations produced by the power generator.
FILED	Friday, April 05, 2019
APPL NO	16/376178
ART UNIT	3786 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 13/00051 (20130101) A61F 13/0253 (20130101) A61F 13/0273 (20130101) A61F 2013/0034 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/205 (20130101) A61N 1/0468 (20130101) Original (OR) Class A61N 1/0492 (20130101) Electric Machines Not Otherwise Provided for H02N 1/04 (20130101) H02N 2/18 (20130101)
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11344727 — Stereognosis training system and method for patients with chronic stroke, spinal cord injury or neuropathy

US 11344727	Kilgard
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S)	Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S)	Michael P. Kilgard (Richardson, Texas)
ABSTRACT	Provided is an effective stereognosis training system that integrates hardware and software to provide a simple, reliable, quantitative system to provide tactile rehabilitation and progress monitoring. The system can include an interactive device including a novel set of objects, that are combined with neuromodulatory systems such as wireless closed-loop vagus nerve stimulation to improve neural plasticity and expedite functional recovery. The system can send updates to therapists or clinicians to monitor progress and encourage compliance with prescribed therapy.
FILED	Tuesday, November 12, 2019
APPL NO	16/681575
ART UNIT	3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0077 (20130101) A61B 5/1128 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36053 (20130101) A61N 1/36103 (20130101) Original (OR) Class A61N 1/36139 (20130101) A61N 1/37211 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 19/003 (20130101)
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11345067 — Mechanical reticulation of polymeric-based closed cell foams

US 11345067	Rodriguez et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California); The Texas A and M University System (College Station, Texas)
ASSIGNEE(S)	LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California); THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas)
INVENTOR(S)	Jennifer N. Rodriguez (Lathrop, California); Duncan J. Maitland (College Station, Texas); Thomas S. Wilson (San Leandro, California)
ABSTRACT	Polymeric based closed cell foams, such as shape memory polymer foams, contain bubbles. Making these bubbles continuous is called reticulation. Disclosed are embodiments of a device and method to controllably reticulate polymer-based closed cell foams by puncturing the membranes of these polymer-based closed cell foams.
FILED	Friday, May 08, 2020
APPL NO	16/870094
ART UNIT	1788 — Miscellaneous Articles, Stock Material
CURRENT CPC	Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/06 (20130101) A61L 31/06 (20130101) A61L 31/146 (20130101) A61L 2400/16 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 44/5663 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2075/00 (20130101) B29K 2105/046 (20130101) B29K 2995/0093 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/18 (20130101) B32B 5/32 (20130101) B32B 2266/08 (20130101) B32B 2266/0278 (20130101) B32B 2535/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/73 (20130101) C08G 18/3228 (20130101) C08G 18/3278 (20130101) C08G 18/3284 (20130101) C08G 2101/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/38 (20130101) C08J 2205/052 (20130101) C08J 2207/10 (20130101) C08J 2375/04 (20130101) Compositions of Macromolecular Compounds C08L 75/04 (20130101) C08L 75/04 (20130101) C08L 2201/12 (20130101) C08L 2203/14 (20130101)
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11345656 — PCNA inhibitors

US 11345656	Malkas et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	City of Hope (Duarte, California)
ASSIGNEE(S)	City of Hope (Duarte, California)
INVENTOR(S)	Linda H. Malkas (Duarte, California); David Horne (Altadena, California); Robert J. Hickey (Duarte, California); Long Gu (Duarte, California)
ABSTRACT	Described herein, inter alia, are compositions of PCNA modulators and methods for treating or preventing cancer.
FILED	Tuesday, December 01, 2020
APPL NO	17/108739
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/167 (20130101) A61K 31/4409 (20130101) A61K 31/4418 (20130101) A61K 31/4418 (20130101) A61K 31/4725 (20130101) A61K 31/4725 (20130101) A61K 33/24 (20130101) A61K 33/243 (20190101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/02 (20180101) Acyclic or Carbocyclic Compounds C07C 233/76 (20130101) Original (OR) Class C07C 237/22 (20130101) Heterocyclic Compounds C07D 213/68 (20130101) C07D 217/26 (20130101) C07D 401/12 (20130101)
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11345670 — Heterocyclic compounds for cancer imaging and treatment and methods for their use

US 11345670	Andersen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The University of British Columbia (Vancouver, Canada); British Columbia Cancer Agency Branch (Vancouver, Canada)
ASSIGNEE(S)	The University of British Columbia (Vancouver, Canada); British Columbia Cancer Agency Branch (Vancouver, Canada)
INVENTOR(S)	Raymond John Andersen (Vancouver, Canada); Javier Garcia Fernandez (Asturias, Spain); Kunzhong Jian (Surrey, Canada); Marianne Dorothy Sadar (West Vancouver, Canada); Nasrin R. Mawji (Burnaby, Canada); Carmen Adriana Banuelos (Richmond, Canada)
ABSTRACT	Compounds having a structure of Formula I: or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R¹, R², R³, R^11a, R^11b, R^11c, R^11d, X, n¹, n², and n³are as defined herein, are provided. Uses of such compounds for modulating androgen receptor activity, imaging diagnostics in cancer and therapeutics, and methods for treatment of subjects in need thereof, including prostate cancer are also provided.
FILED	Friday, May 01, 2020
APPL NO	16/864479
ART UNIT	1629 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/4164 (20130101) A61K 31/4164 (20130101) A61K 31/4192 (20130101) A61K 31/4192 (20130101) A61K 31/5375 (20130101) A61K 31/5375 (20130101) A61K 45/06 (20130101) A61K 51/0453 (20130101) A61K 51/0459 (20130101) A61K 51/0463 (20130101) A61K 51/0465 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) General Methods of Organic Chemistry; Apparatus Therefor C07B 59/002 (20130101) Heterocyclic Compounds C07D 233/60 (20130101) C07D 249/04 (20130101) Original (OR) Class C07D 265/30 (20130101) C07D 295/084 (20130101) C07D 295/088 (20130101)
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11345725 — Bis-thioether stapled peptides as inhibitors of PRC2 function

US 11345725	Gerona-Navarro et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF)
APPLICANT(S)	Research Foundation of the City University of New York (New York, New York)
ASSIGNEE(S)	Research Foundation of the City University of New York (New York, New York)
INVENTOR(S)	Guillermo Gerona-Navarro (New York, New York); Gan Zhang (Brooklyn, New York); Flavia Barragan (Berlin, Germany)
ABSTRACT	This disclosure describes three novel bisthioether stapled peptides as allosteric inhibitors of Polycomb Repressive Complex 2 (PRC2) catalytic function with demonstrated cell permeability, potent activity in physiological conditions, and strong antiproliferative effects on cancer cells. These inhibitors target, for the first time, two protein interfaces in PRC2 that are crucial for its proper assembling and thus for its histone methyltransferase activity.
FILED	Wednesday, September 16, 2020
APPL NO	17/022900
ART UNIT	1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Peptides C07K 7/08 (20130101) Original (OR) Class
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11345735 — Fully-human t-cell receptor specific for the 369-377 epitope derived from the Her2/neu (ERBB2) receptor protein

US 11345735	Powell, Jr.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S)	THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
INVENTOR(S)	Daniel J. Powell, Jr. (Bala Cynwyd, Pennsylvania)
ABSTRACT	The present invention relates to compositions and methods for treating HER2/Neu (ERBB2) expressing cancer cells. In some embodiments, the invention includes an isolated T cell receptor (TCR) having high affinity for and that specifically binds ERBB2_369-377epitope on a target cell. Other embodiments include a T cell or a population of T cells modified to express ERBB2-specific TCR. Further embodiments include methods of using ERBB2-specific TCR gene transfer for treating ERBB2 expressing cancer cells. Also included are methods and pharmaceutical compositions comprising the modified T cells for adoptive therapy.
FILED	Wednesday, August 07, 2019
APPL NO	16/534344
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Peptides C07K 14/82 (20130101) C07K 14/4705 (20130101) C07K 14/7051 (20130101) Original (OR) Class C07K 16/28 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/12 (20130101)
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11345738 — Compounds for treating neurodegenerative proteinopathies

US 11345738	Golde et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Aging (NIA)
APPLICANT(S)	University of Florida Research Foundation, Incorporated (Gainesville, Florida)
ASSIGNEE(S)	University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S)	Todd E. Golde (Gainesville, Florida); Paramita Chakrabarty (Gainesville, Florida)
ABSTRACT	This invention relates to compounds (e.g., those delineated herein), pharmaceutically acceptable salts, prodrugs, solveates, and hydrates thereof. This invention also provides compositions comprising a compound of this invention and the use of such compounds and compositions in methods of treating diseases and conditions that are beneficially treated by administering modulating compounds or compositions that modulate Aβ, PAMPS and DAMPS.
FILED	Tuesday, June 19, 2018
APPL NO	16/011728
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/177 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Peptides C07K 14/705 (20130101) C07K 14/70596 (20130101) Original (OR) Class C07K 2319/30 (20130101) C07K 2319/31 (20130101) C07K 2319/32 (20130101) C07K 2319/40 (20130101) C07K 2319/43 (20130101)
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11345740 — Fetal hemoglobin for genetic correction of sickle cell disease

US 11345740	Malik
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Children's Hospital Medical Center (Cincinnati, Ohio)
ASSIGNEE(S)	Children's Hospital Medical Center (Cincinnati, Ohio)
INVENTOR(S)	Punam Malik (Cincinnati, Ohio)
ABSTRACT	Methods and compositions disclosed herein generally relates to methods of determining minimum hematopoietic stem cell (HSC) chimerism and gene dosage for correction of a hematopoietic disease; in particular, in in vivo models. The invention also relates to modified lentiviral expression vectors for increasing a viral titer and various methods for increasing such titers as well as expression vectors capable of enhancing such titers. The invention also relates to CHS4 chromatin insulator-derived functional insulator sequences. The invention also relates to methods for genetic correction of diseases or reducing symptoms thereof, such as sickle cell anemia or β-thalassemia.
FILED	Friday, June 01, 2018
APPL NO	15/995675
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) Peptides C07K 14/805 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2740/10043 (20130101) C12N 2740/16043 (20130101) C12N 2830/008 (20130101) C12N 2830/40 (20130101) C12N 2830/50 (20130101)
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11345741 — Human monoclonal antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

US 11345741	Crowe, Jr. et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S)	Vanderbilt University (Nashville, Tennessee)
INVENTOR(S)	James E. Crowe, Jr. (Nashville, Tennessee); Seth Zost (Nashville, Tennessee); Robert Carnahan (Nashville, Tennessee); Pavlo Gilchuk (Nashville, Tennessee)
ABSTRACT	The present disclosure is directed to antibodies binding to and neutralizing the coronavirus designated SARS-CoV-2 and methods for use thereof.
FILED	Thursday, March 25, 2021
APPL NO	17/212949
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) A61K 2039/507 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/52 (20130101) C07K 2317/55 (20130101) C07K 2317/76 (20130101) C07K 2317/94 (20130101) C07K 2317/565 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101)
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11345743 — Antibody-mediated neutralization of chikungunya virus

US 11345743	Crowe, Jr. et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	VANDERBILT UNIVERSITY (Nashville, Tennessee)
ASSIGNEE(S)	VANDERBILT UNIVERSITY (Nashville, Tennessee)
INVENTOR(S)	James E. Crowe, Jr. (Nashville, Tennessee); Scott A. Smith (White Bluff, Tennessee); Terence Dermody (Brentwood, Tennessee); Laurie Silva (Nashville, Tennessee)
ABSTRACT	The present disclosure is directed to antibodies binding to and neutralizing Chikungunya virus (CHIKV) and methods for use thereof.
FILED	Thursday, October 10, 2019
APPL NO	16/598380
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/12 (20130101) A61K 39/395 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) Peptides C07K 16/1081 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/34 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/70 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/181 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101)
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11345748 — Method of treating idiopathic pulmonary fibrosis and kidney fibrosis

US 11345748	Hotamisligil et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Gökhan S. Hotamisligil (Weston, Massachusetts); Kosei Eguchi (Brookline, Massachusetts)
ABSTRACT	Provided herein are compounds, compositions, and methods of identifying compounds that neutralize the ability of the cannabinoid receptor type-1 (CB1) agonist 2-arachidonylglycerol (2-AG) in complex with its obligate binding partner adipocyte lipid binding protein (aP2) from agonizing CB1 signaling in peripheral tissues. Further provided herein are methods of treating a disorder associated with dysregulated or abnormal hepatic de novo lipogenesis and/or hepatic selective insulin resistance by inhibiting cannabinoid receptor type-1 (CB1) agonist 2-arachidonylglycerol (2-AG) in complex with its obligate binding partner adipocyte lipid binding protein (aP2) from binding and agonizing CB1.
FILED	Monday, December 09, 2019
APPL NO	16/708015
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/16 (20180101) A61P 3/04 (20180101) A61P 3/10 (20180101) Peptides C07K 16/18 (20130101) Original (OR) Class
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11345771 — Compositions and methods of promoting organic photocatalysis

US 11345771	Miyake et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado); COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colorado)
ASSIGNEE(S)	The Regents of the University of Colorado (Denver, Colorado); Colorado State University Research Foundation (Fort Collins, Colorado)
INVENTOR(S)	Garret Miyake (Fort Collins, Colorado); Jordan Corinne Theriot (Denver, Colorado); Matthew D. Ryan (Longmont, Colorado); Ryan Michael Pearson (Fort Collins, Colorado); Tracy Allen French (Fircrest, Washington); Haishen Yang (Shanghai, China PRC); Andrew Lockwood (Kent, United Kingdom); Charles Musgrave (Longmont, Colorado); Chern-Hooi Lim (Boulder, Colorado); Ya Du (Shanghai, China PRC); Blaine McCarthy (Fort Collins, Colorado)
ABSTRACT	The invention provides novel compounds and methods that are useful in promoting reactions that proceed through an oxidative quenching pathway. In certain embodiments, the reactions comprise atom transfer radical polymerization.
FILED	Tuesday, March 02, 2021
APPL NO	17/190110
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/0244 (20130101) B01J 2231/12 (20130101) B01J 2231/42 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 37/02 (20130101) C07B 39/00 (20130101) C07B 41/00 (20130101) C07B 43/00 (20130101) C07B 45/00 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 2/48 (20130101) C08F 2/50 (20130101) C08F 4/40 (20130101) C08F 20/14 (20130101) C08F 212/08 (20130101) C08F 218/08 (20130101) C08F 220/14 (20130101) C08F 220/22 (20130101) C08F 220/44 (20130101) C08F 220/285 (20200201) C08F 220/1804 (20200201) C08F 220/1807 (20200201) C08F 220/1811 (20200201) Original (OR) Class C08F 230/085 (20200201) C08F 2438/01 (20130101)
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11345895 — Induction of arterial-type of hemogenic endothelium (AHE) and enhancement of T cell production from PSCs through overexpression of ETS factors or modulating MAPK/ERK signalling pathways

US 11345895	Slukvin et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) NIH Office of the Director (NIHOD)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S)	Igor I. Slukvin (Verona, Wisconsin); Mi Ae Park (Madison, Wisconsin); Akhilesh Kumar (Madison, Wisconsin)
ABSTRACT	The present invention is a method of creating a population of hemogenic endothelial cells with arterial specification and enhanced T cell potential. In one embodiment, the method uses ETS transgene induction at the mesodermal stage of differentiation. In another embodiment, the method activates ERK and NOTCH signaling at the mesodermal stage of differentiation.
FILED	Friday, November 17, 2017
APPL NO	15/816914
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 2035/124 (20130101) Peptides C07K 14/4702 (20130101) C07K 14/70503 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/069 (20130101) Original (OR) Class C12N 5/0636 (20130101) C12N 5/0647 (20130101) C12N 2501/42 (20130101) C12N 2501/60 (20130101) C12N 2501/602 (20130101) C12N 2501/727 (20130101) C12N 2506/02 (20130101) C12N 2506/28 (20130101) C12N 2506/45 (20130101) C12N 2510/00 (20130101)
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11345911 — Regulation of RAN translation by PKR and eIF2A-P pathways

US 11345911	Ranum et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	University of Florida Research Foundation, Incorporated (Gainesville, Florida)
ASSIGNEE(S)	University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S)	Laura Ranum (Gainesville, Florida); Tao Zu (Gainesville, Florida)
ABSTRACT	Methods and compositions for modulating repeat non-ATG protein (RAN protein) translation are provided. In some aspects, the disclosure provides methods of inhibiting RAN protein translation by contacting a cell with an effective amount of an inhibitor of eIF2 phosphorylation or an inhibitor of protein kinase R (PKR). In some embodiments, methods described by the disclosure are useful for treating diseases associated with RAN protein translation, such as certain neurodegenerative diseases.
FILED	Tuesday, April 17, 2018
APPL NO	16/605992
ART UNIT	1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 31/7105 (20130101) A61K 35/761 (20130101) A61K 38/45 (20130101) Peptides C07K 14/47 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/66 (20130101) C12N 15/102 (20130101) Original (OR) Class C12N 2750/14143 (20130101) Enzymes C12Y 207/01037 (20130101)
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11345912 — Directed evolution of multivalent glycopeptides that tightly bind to target proteins

US 11345912	Krauss et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Brandeis University (Waltham, Massachusetts); The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S)	BRANDEIS UNIVERSITY (Waltham, Massachusetts)
INVENTOR(S)	Isaac J. Krauss (Waltham, Massachusetts); Satoru Horiya (Waltham, Massachusetts); Yollete V. Guillen Schlippe (Boston, Massachusetts)
ABSTRACT	The invention relates to a method for selecting a glycopolypeptide that binds to a target protein, the method including the steps of providing a pool of glycopolypeptides fused via puromycin linker to an encoding mRNA-cDNA duplex; combining the pool with a target protein to form a mixture; incubating the mixture for a period of time sufficient to allow any target protein to bind to one or more of the glycopolypeptides, thereby forming glycopolypeptide-target protein complexes; and isolating from the mixture the glycopolypeptide-target protein complexes, thereby identifying a plurality of selected glycopolypeptides.
FILED	Thursday, December 12, 2019
APPL NO	16/711964
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/21 (20130101) A61K 2039/575 (20130101) Peptides C07K 16/1063 (20130101) C07K 19/00 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2319/91 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1058 (20130101) Original (OR) Class C12N 15/1062 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6845 (20130101) G01N 2405/00 (20130101)
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11345927 — Compositions for reducing sarcolipin expression and preventing and treating muscular dystrophy and cardiomyopathy and methods of use

US 11345927	Babu
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)	Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
ASSIGNEE(S)	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey)
INVENTOR(S)	Gopal J. Babu (Randolph, New Jersey)
ABSTRACT	Compositions, recombinant viruses, and recombinant viral vectors for inhibiting sarcolipin (SLN) expression or activity in a cell and for preventing or treating Duchenne Muscular Dystrophy (DMD) in a subject (e.g., a human patient having or predisposed to having DMD) and in some embodiments additionally cardiomyopathy, include a therapeutically effective amount of an inhibitor of SLN. Methods of using these compositions, recombinant viruses, and recombinant viral vectors are also described herein. These compositions, recombinant viruses, and recombinant viral vectors and methods of use provide novel therapies for DMD and associated cardiomyopathy based on the reduction of SLN expression and/or activity.
FILED	Monday, January 22, 2018
APPL NO	16/479838
ART UNIT	1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 15/113 (20130101) C12N 2310/531 (20130101) C12N 2320/32 (20130101) C12N 2750/14141 (20130101)
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11345931 — Cas discrimination using tuned guide RNA

US 11345931	Chavez et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Human Genome Research Institute (NHGRI)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Alejandro Chavez (New York, New York); Benjamin W. Pruitt (Cambridge, Massachusetts)
ABSTRACT	CRISPR/Cas Systems are provided where a tuned guide RNA is used to discriminate between two protospacer sequences of same length that differ by one nucleotide.
FILED	Wednesday, December 14, 2016
APPL NO	16/061363
ART UNIT	1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/102 (20130101) C12N 15/902 (20130101) Original (OR) Class C12N 15/1082 (20130101) C12N 2310/20 (20170501) C12N 2800/80 (20130101)
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11345956 — Methods and compositions related to prostate cancer therapeutics

US 11345956	Luo et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
INVENTOR(S)	Jun Luo (Clarksville, Maryland); Emmanuel S. Antonarakis (Silver Spring, Maryland); Changxue Lu (Ellicott City, Maryland); William Isaacs (Reisterstown, Maryland)
ABSTRACT	Disclosed herein are compositions and methods for detecting biological molecules and biomarkers associated with prostate cancer. Disclosed herein are compositions and methods for detecting biological molecules and biomarkers associated with castration-resistant prostate cancer wherein such biological molecules and biomarkers comprise androgen-receptor splice variants that can be used to develop effective therapeutic regimens for prostate cancer patients. Disclosed herein are methods of using biological molecules and biomarkers related to androgen-receptor splice variants for assessing therapeutic resistance to drugs such as enzalutamide and abiraterone.
FILED	Tuesday, August 25, 2015
APPL NO	15/505882
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 39/00 (20130101) A61K 39/001102 (20180801) A61K 45/06 (20130101) A61K 2039/6056 (20130101) A61K 2300/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class C12Q 1/686 (20130101) C12Q 1/6853 (20130101) C12Q 2521/107 (20130101) C12Q 2521/107 (20130101) C12Q 2539/103 (20130101) C12Q 2539/103 (20130101) C12Q 2545/114 (20130101) C12Q 2545/114 (20130101)
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11346840 — Biofilm formation to define risk for colon cancer

US 11346840	Sears et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S)	The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	Cynthia L. Sears (Baltimore, Maryland); Drew M. Pardoll (Brookeville, Maryland); Christine Craig (Baltimore, Maryland); Elizabeth Wick (Baltimore, Maryland)
ABSTRACT	Methods of identifying subjects at increased risk of cancer, based upon detection of biofilms and/or biofilm-associated microbes within a subject, are disclosed. Therapies designed to prevent formation and/or reduce the size of biofilms in a subject identified to be at increased risk of cancer based upon detection of biofilms and/or biofilm-associated microbes are disclosed. In particular embodiments, the invention provides for identification of a subject at elevated risk of developing or having colorectal cancer and/or a colorectal adenoma, based upon detection of a biofilm and/or biofilm-associated bacteria within the gastrointestinal tract of the subject (optionally, within a biopsy specimen and/or stool sample of such subject). Therapies involving administration of an antibiotic agent and/or a probiotic agent to a subject, to prevent or reduce biofilm formation within the gastrointestinal tract of the subject, optionally provided in combination with additional cancer therapy, are also disclosed.
FILED	Monday, December 31, 2018
APPL NO	16/237112
ART UNIT	1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/43 (20130101) A61K 31/165 (20130101) A61K 31/407 (20130101) A61K 31/546 (20130101) A61K 31/7048 (20130101) A61K 31/7056 (20130101) A61K 35/741 (20130101) A61K 35/742 (20130101) A61K 35/744 (20130101) A61K 35/745 (20130101) A61K 35/747 (20130101) A61K 45/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/04 (20130101) C12Q 1/689 (20130101) C12Q 1/6841 (20130101) C12Q 1/6869 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57419 (20130101) Original (OR) Class G01N 2800/50 (20130101) G01N 2800/7028 (20130101)
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11346842 — Single molecule peptide sequencing methods

US 11346842	Boyden et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Edward Boyden (Cambridge, Massachusetts); Adam Henry Marblestone (Cambridge, Massachusetts); Samuel Gordon Rodriques (Cambridge, Massachusetts)
ABSTRACT	The invention, in part, includes methods of single molecule protein sequencing that include using weak binding spectra in the amino acid identification.
FILED	Monday, June 22, 2020
APPL NO	16/907831
ART UNIT	1796 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/37 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/76 (20130101) G01N 21/6428 (20130101) G01N 21/6458 (20130101) G01N 33/6824 (20130101) Original (OR) Class G01N 2333/948 (20130101)
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11348227 — Image registration using a fully convolutional network

US 11348227	Fan et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S)	The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S)	Yong Fan (Bala Cynwyd, Pennsylvania); Hongming Li (Philadelphia, Pennsylvania)
ABSTRACT	Methods and systems for analyzing images are disclosed. An example method may comprise inputting one or more of a first image or a second image into a fully convolutional network, and determining an updated fully convolutional network by optimizing a similarity metric associated with spatially transforming the first image to match the second image. The one or more values of the fully convolutional network may be adjusted to optimize the similarity metric. The method may comprise registering one or more of the first image or the second image based on the updated fully convolutional network.
FILED	Wednesday, September 04, 2019
APPL NO	16/560235
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6215 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 7/33 (20170101) G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/20081 (20130101) Image or Video Recognition or Understanding G06V 10/25 (20220101)
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11349482 — Integrated circuit for low-voltage thermoelectric energy harvesting with self-start

US 11349482	Bose et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)	Oregon State University (Corvallis, Oregon)
ASSIGNEE(S)	Oregon State University (Corvallis, Oregon)
INVENTOR(S)	Soumya Bose (Corvallis, Oregon); Matthew Johnston (Corvallis, Oregon); Tejasvi Anand (Corvallis, Oregon)
ABSTRACT	The integrated circuit (IC) described herein lowers the start-up voltage to, for example, 50 mV, compatible for starting a DC-DC converter from a thermoelectric generator (TEG), even with a small temperature gradient. The IC further improves end-to-end efficiency of the energy harvester by improving power efficiency of the DC-DC converter while ensuring maximum power transfer from the TEG at low voltages. The IC uses a low voltage integrated charge pump that can boost sub-100 mV input voltage. A startup clock is generated by a ring-oscillator that begins operation with low supply (e.g., 50 mV or less), and which allows for one inductor to be used for DC-DC converter and for startup of the converter. The IC can be configured between the TEG and any downstream sensor or communication circuits to provide an acceptable (e.g., greater than 1 V) voltage for powering the downstream circuits from a low-voltage (e.g., less than 200 mV) TEG energy source.
FILED	Friday, April 03, 2020
APPL NO	16/840147
ART UNIT	2839 — Electrical Circuits and Systems
CURRENT CPC	Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/36 (20130101) H02M 3/155 (20130101) Pulse Technique H03K 3/0315 (20130101) H03K 19/20 (20130101) Original (OR) Class
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Department of Defense (DOD)

11344217 — NMR sensor and methods for rapid, non-invasive determination of hydration state or vascular volume of a subject

US 11344217	Cima et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Michael J. Cima (Winchester, Massachusetts); Matthew Li (Somerville, Massachusetts); Christophoros C. Vassiliou (El Cerrito, California); Negar Tavassolian (Hoboken, New Jersey); Lina Avancini Colucci (Lexington, Massachusetts)
ABSTRACT	The invention features methods for detecting the hydration state or vascular volume of a subject using a device capable of nuclear magnetic resonance (NMR) measurement. The methods involve exposing a portion of a tissue of the subject in vivo to a magnetic field and RF pulse from the device to excite hydrogen nuclei of water within the tissue portion, and measuring a relaxation parameter of the hydrogen nuclei in the tissue portion, the relaxation parameter being a quantitative measure of the hydration state or vascular volume of the subject as a whole. The invention also features devices and computer-readable storage media for performing the methods of the invention.
FILED	Friday, September 05, 2014
APPL NO	14/896806
ART UNIT	3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/02 (20130101) A61B 5/055 (20130101) Original (OR) Class A61B 5/443 (20130101) A61B 5/4875 (20130101) A61B 5/6826 (20130101) A61B 5/14535 (20130101) A61B 5/14542 (20130101) A61B 2560/0431 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) G01R 33/383 (20130101) G01R 33/448 (20130101) G01R 33/4608 (20130101)
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11344283 — Ultrasound waveform tomography with spatial and edge regularization

US 11344283	Huang et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Congressionally Directed Medical Research Programs (CDMRP) Department of Energy (DOE) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Los Alamos National Laboratory (LANL) Federally Funded Research and Development Center (FFRDC) Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)	Los Alamos National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S)	TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico)
INVENTOR(S)	Lianjie Huang (Los Alamos, New Mexico); Youzuo Lin (Los Alamos, New Mexico)
ABSTRACT	Synthetic-aperture ultrasound tomography systems and methods using scanning arrays and algorithms configured to simultaneously acquire ultrasound transmission and reflection data, and process the data for improved ultrasound tomography imaging, wherein the tomography imaging comprises total-variation regularization, or a modified total variation regularization, particularly with edge-guided or spatially variant regularization.
FILED	Monday, July 23, 2018
APPL NO	16/043071
ART UNIT	3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0073 (20130101) A61B 5/7275 (20130101) A61B 8/13 (20130101) A61B 8/14 (20130101) A61B 8/15 (20130101) A61B 8/085 (20130101) A61B 8/145 (20130101) A61B 8/406 (20130101) A61B 8/483 (20130101) A61B 8/0825 (20130101) A61B 8/4477 (20130101) A61B 8/4488 (20130101) A61B 8/4494 (20130101) A61B 8/5207 (20130101) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 15/8915 (20130101) G01S 15/8929 (20130101) G01S 15/8997 (20130101) Image Data Processing or Generation, in General G06T 5/001 (20130101) G06T 11/005 (20130101)
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11344577 — Car+ T cells genetically modified to eliminate expression of T-cell receptor and/or HLA

US 11344577	Cooper et al.
FUNDED BY	Department of Defense (DOD) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S)	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S)	Laurence J. Neil Cooper (Houston, Texas); Hiroki Torikai (Houston, Texas)
ABSTRACT	The present invention concerns methods and compositions for immunotherapy employing a modified T cell comprising disrupted T cell receptor and/or HLA and comprising a chimeric antigen receptor. In certain embodiments, the compositions are employed allogeneically as universal reagents for “off-the-shelf” treatment of medical conditions such as cancer, autoimmunity, and infection. In particular embodiments, the T cell receptor-negative and/or HLA-negative T cells are generated using zinc finger nucleases, for example.
FILED	Monday, July 08, 2019
APPL NO	16/504427
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 39/0011 (20130101) A61K 39/00111 (20180801) A61K 39/00117 (20180801) A61K 39/00119 (20180801) A61K 39/001104 (20180801) A61K 39/001106 (20180801) A61K 39/001109 (20180801) A61K 39/001112 (20180801) A61K 39/001117 (20180801) A61K 39/001119 (20180801) A61K 39/001124 (20180801) A61K 39/001129 (20180801) A61K 39/001151 (20180801) A61K 39/001164 (20180801) A61K 39/001171 (20180801) A61K 39/001174 (20180801) A61K 39/001181 (20180801) A61K 39/001182 (20180801) A61K 2039/5156 (20130101) A61K 2039/5158 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2510/00 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101)
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11344633 — Anti-nucleolin agent-conjugated nanoparticles

US 11344633	Bates et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	University of Louisville Research Foundation, Inc. (Louisville, Kentucky)
ASSIGNEE(S)	University of Louisville Research Foundation, Inc (Louisville, Kentucky)
INVENTOR(S)	Paula J. Bates (Louisville, Kentucky); Mohammad Tariq Malik (Prospect, Kentucky); Kyung A. Kang (Louisville, Kentucky)
ABSTRACT	A composition comprises an anti-nucleolin agent conjugated to nanoparticles. The nanoparticles are non-magnetic, not iron oxide and not polyacrylamide. Furthermore, a pharmaceutical composition for treating cancer comprises a composition including an anti-nucleolin agent conjugated to nanoparticles, and a pharmaceutically acceptable carrier.
FILED	Thursday, August 18, 2016
APPL NO	15/240780
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 47/61 (20170801) A61K 47/62 (20170801) A61K 47/6923 (20170801) A61K 47/6929 (20170801) A61K 49/04 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115)
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11344723 — System and method for decoding and behaviorally validating memory consolidation during sleep from EEG after waking experience

US 11344723	Roach et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S)	HRL Laboratories, LLC (Malibu, California)
INVENTOR(S)	Shane M. Roach (San Francisco, California); Praveen K. Pilly (West Hills, California)
ABSTRACT	Described is a system for decoding and validating memory consolidation. During operation, the system receives electroencephalographic (EEG) data while a subject is performing a specific task. Nuisance signals are then removed from the EEG data, resulting in a nuisance free signal. Skill feature vectors are generated from the nuisance free signal using time-invariant feature extraction. A skill classifier can then be trained for the specific task based on the skill feature vectors to generate a subject specific model regarding a memory replay for the specific task. Finally, electrodes in a neural cap are activated based on the memory replay.
FILED	Friday, November 23, 2018
APPL NO	16/199108
ART UNIT	3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/316 (20210101) A61B 5/369 (20210101) A61B 5/726 (20130101) A61B 5/4836 (20130101) A61B 5/7203 (20130101) A61B 5/7267 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/025 (20130101) A61N 1/0408 (20130101) A61N 1/0476 (20130101) A61N 1/0484 (20130101) A61N 1/36025 (20130101) Original (OR) Class
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11345123 — Monolithic integration of hybrid perovskite single crystals with silicon for highly sensitive x-ray detectors

US 11345123	Huang et al.
FUNDED BY	Department of Defense (DOD) Defense Threat Reduction Agency (DTRA)
APPLICANT(S)	NUtech Ventures (Lincoln, Nebraska)
ASSIGNEE(S)	The Board of Regents of the University of Nebraska (Lincoln, Nebraska)
INVENTOR(S)	Jinsong Huang (Lincoln, Nebraska); Wei Wei (Lincoln, Nebraska)
ABSTRACT	Perovskite single crystal X-ray radiation detector devices including an X-ray wavelength-responsive active layer including an organolead trihalide perovskite single crystal, a substrate layer comprising an oxide, and a binding layer disposed between the active layer and the substrate layer. The binding layer including a binding molecule having a first functional group that bonds to the organolead trihalide perovskite single crystal and a second functional group that bonds with the oxide. Inclusion of the binding layer advantageously reduces device noise while retaining signal intensity.
FILED	Monday, January 07, 2019
APPL NO	16/241071
ART UNIT	2884 — Optics
CURRENT CPC	Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 27/08 (20130101) Original (OR) Class Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 4/00 (20130101) G21K 2004/04 (20130101)
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11345460 — Rotatable empennage for an aircraft

US 11345460	Joo
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S)	United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S)	James Joo (Centerville, Ohio)
ABSTRACT	An aircraft having an empennage rotatable about a longitudinal axis via an electric motor drive is disclosed herein. A pair of horizontal stabilizers extend from opposing sides of the rotatable empennage and are independently rotatable via electric motor drives. The rotatable empennage is operable for controlling yaw, pitch and rolling moments without a traditional vertical stabilizer and rudder system which can reduce weight as well as the radar cross section of the aircraft. This technology can also be applied to a weapon control system such missile such as a missile.
FILED	Friday, May 29, 2020
APPL NO	16/886932
ART UNIT	3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Aeroplanes; Helicopters B64C 5/02 (20130101) Original (OR) Class B64C 13/34 (20130101) B64C 13/503 (20130101)
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11345653 — Compositions and methods for reactivating cholinesterases

US 11345653	Khavrutskii et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Development Command (USAMRDC) U.S. Army Medical Research and Materiel Command (USAMRMC) Uniformed Services University of the Health Sciences (USUHS) Henry M Jackson Foundation for the Advancement of Military Medicine, Inc (HJF)
APPLICANT(S)	The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland); The Government of the United States as Represented by the Secretary of the Army (Fort Detrick, Maryland)
ASSIGNEE(S)	The Henry M. Jackson Foundation for the Advancement of Military Medicine Inc. (Bethesda, Maryland); The Government of the United States as Represented by the Secretary of the Army (Fort Detrick, Maryland)
INVENTOR(S)	Ilja Khavrutskii (Brunswick, Maryland); Sven Anders Wallqvist (Frederick, Maryland)
ABSTRACT	The invention relates to compounds, compositions and methods for activating, reactivating, reversing or preventing the deactivation of cholinesterases, such as acetylcholinesterase and butyrylcholinesterase.
FILED	Friday, June 16, 2017
APPL NO	16/310686
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 215/68 (20130101) Original (OR) Class
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11345656 — PCNA inhibitors

US 11345656	Malkas et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	City of Hope (Duarte, California)
ASSIGNEE(S)	City of Hope (Duarte, California)
INVENTOR(S)	Linda H. Malkas (Duarte, California); David Horne (Altadena, California); Robert J. Hickey (Duarte, California); Long Gu (Duarte, California)
ABSTRACT	Described herein, inter alia, are compositions of PCNA modulators and methods for treating or preventing cancer.
FILED	Tuesday, December 01, 2020
APPL NO	17/108739
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/167 (20130101) A61K 31/4409 (20130101) A61K 31/4418 (20130101) A61K 31/4418 (20130101) A61K 31/4725 (20130101) A61K 31/4725 (20130101) A61K 33/24 (20130101) A61K 33/243 (20190101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/02 (20180101) Acyclic or Carbocyclic Compounds C07C 233/76 (20130101) Original (OR) Class C07C 237/22 (20130101) Heterocyclic Compounds C07D 213/68 (20130101) C07D 217/26 (20130101) C07D 401/12 (20130101)
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11345741 — Human monoclonal antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

US 11345741	Crowe, Jr. et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S)	Vanderbilt University (Nashville, Tennessee)
INVENTOR(S)	James E. Crowe, Jr. (Nashville, Tennessee); Seth Zost (Nashville, Tennessee); Robert Carnahan (Nashville, Tennessee); Pavlo Gilchuk (Nashville, Tennessee)
ABSTRACT	The present disclosure is directed to antibodies binding to and neutralizing the coronavirus designated SARS-CoV-2 and methods for use thereof.
FILED	Thursday, March 25, 2021
APPL NO	17/212949
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) A61K 2039/507 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/52 (20130101) C07K 2317/55 (20130101) C07K 2317/76 (20130101) C07K 2317/94 (20130101) C07K 2317/565 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101)
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11345743 — Antibody-mediated neutralization of chikungunya virus

US 11345743	Crowe, Jr. et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	VANDERBILT UNIVERSITY (Nashville, Tennessee)
ASSIGNEE(S)	VANDERBILT UNIVERSITY (Nashville, Tennessee)
INVENTOR(S)	James E. Crowe, Jr. (Nashville, Tennessee); Scott A. Smith (White Bluff, Tennessee); Terence Dermody (Brentwood, Tennessee); Laurie Silva (Nashville, Tennessee)
ABSTRACT	The present disclosure is directed to antibodies binding to and neutralizing Chikungunya virus (CHIKV) and methods for use thereof.
FILED	Thursday, October 10, 2019
APPL NO	16/598380
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/12 (20130101) A61K 39/395 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) Peptides C07K 16/1081 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/34 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/70 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/181 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101)
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11345920 — Artificial nucleic acid molecules for improved protein expression

US 11345920	Thess et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	CureVac AG (Tübingen, Germany)
ASSIGNEE(S)	CureVac AG (Tübingen, Germany)
INVENTOR(S)	Andreas Thess (Kusterdingen, Germany); Thomas Schlake (Gundelfingen, Germany); Stefanie Grund (Stuttgart, Germany)
ABSTRACT	The invention relates to an artificial nucleic acid molecule comprising an open reading frame and a 3′-UTR comprising at least one poly(A) sequence or a polyadenylation signal. The invention also relates to a method for increasing protein production from an artificial nucleic acid molecule and to the use of a 3′-UTR for a method for increasing protein production from an artificial nucleic acid molecule. Moreover, the invention concerns the use of the artificial nucleic acid molecule as a medicament, as a vaccine or in gene therapy.
FILED	Sunday, December 05, 2021
APPL NO	17/542430
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/145 (20130101) A61K 39/205 (20130101) A61K 48/00 (20130101) A61K 2039/53 (20130101) A61K 2039/54 (20130101) A61K 2039/575 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/67 (20130101) Original (OR) Class C12N 15/68 (20130101) C12N 15/85 (20130101) C12N 2760/16134 (20130101) C12N 2760/16171 (20130101) C12N 2760/20134 (20130101) C12N 2760/20171 (20130101) C12N 2830/50 (20130101)
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11345956 — Methods and compositions related to prostate cancer therapeutics

US 11345956	Luo et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
INVENTOR(S)	Jun Luo (Clarksville, Maryland); Emmanuel S. Antonarakis (Silver Spring, Maryland); Changxue Lu (Ellicott City, Maryland); William Isaacs (Reisterstown, Maryland)
ABSTRACT	Disclosed herein are compositions and methods for detecting biological molecules and biomarkers associated with prostate cancer. Disclosed herein are compositions and methods for detecting biological molecules and biomarkers associated with castration-resistant prostate cancer wherein such biological molecules and biomarkers comprise androgen-receptor splice variants that can be used to develop effective therapeutic regimens for prostate cancer patients. Disclosed herein are methods of using biological molecules and biomarkers related to androgen-receptor splice variants for assessing therapeutic resistance to drugs such as enzalutamide and abiraterone.
FILED	Tuesday, August 25, 2015
APPL NO	15/505882
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 39/00 (20130101) A61K 39/001102 (20180801) A61K 45/06 (20130101) A61K 2039/6056 (20130101) A61K 2300/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class C12Q 1/686 (20130101) C12Q 1/6853 (20130101) C12Q 2521/107 (20130101) C12Q 2521/107 (20130101) C12Q 2539/103 (20130101) C12Q 2539/103 (20130101) C12Q 2545/114 (20130101) C12Q 2545/114 (20130101)
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11346017 — Single crystalline NaUO₃and method of making same

US 11346017	Mann et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S)	United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S)	James M. Mann (Springboro, Ohio); Thomas A. Bowen (Beavercreek, Ohio); Eric J. Plummer (Beavercreek, Ohio)
ABSTRACT	The present invention relates to single crystalline NaUO₃, hydrothermal growth processes of making such single crystals and methods of using such single crystals. In particular, Applicants disclose single crystalline NaUO₃in the R32 space group. Unlike other powdered NaUO₃, Applicants' single crystalline NaUO₃has a sufficient crystal size to be characterized and used in the fields of laser light, infrared countermeasures, nuclear fuel material, nuclear forensics and magnetic applications.
FILED	Friday, August 23, 2019
APPL NO	16/549309
ART UNIT	1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 43/01 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/10 (20130101) C30B 29/22 (20130101) Original (OR) Class
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11346253 — Liner apparatus and method of inspecting and/or cleaning a liner annular region

US 11346253	Singh et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Air Systems Command (NAVAIR)
APPLICANT(S)	United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S)	Raytheon Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Anshuman Singh (Edmond, Oklahoma); Rachelle Parsons (Broad Brook, Connecticut); Mahamoud Coulibaly (East Hartford, Connecticut); Daniel Cheng (West Hartford, Connecticut); Paul Rosencrans (Norman, Oklahoma)
ABSTRACT	A liner for a gas turbine engine is provided that includes an outer wall, an inner wall, and a plurality of structural elements disposed between the inner wall and the outer wall. The outer wall is spaced apart from the inner wall and is disposed radially outside of the inner wall. The outer wall and inner wall form an annular structure having a circumference, and an annular region disposed between the first interior surface of the outer wall and the second interior surface of the inner wall. Each of the structural elements is attached to the outer wall and the inner wall. The outer wall includes at least one inspection port extending through the outer wall configured for access to the annular region disposed between the first interior surface of the outer wall and the second interior surface of the inner wall.
FILED	Friday, March 22, 2019
APPL NO	16/362144
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Cleaning in General; Prevention of Fouling in General B08B 5/04 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/24 (20130101) F01D 25/26 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/72 (20130101) F05D 2240/14 (20130101) F05D 2260/202 (20130101)
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11346329 — Propulsion systems including an electrically actuated valve

US 11346329	Lozano et al.
FUNDED BY	Department of Defense (DOD) National Reconnaissance Office (NRO)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Paulo C. Lozano (Arlington, Massachusetts); Dakota Freeman (Cambridge, Massachusetts)
ABSTRACT	Propulsion systems, such as electrospray thrusters, may include an electrically actuated valve to permit a selective flow of propellant to a thruster. The valve may be located and arranged such that it physically separates a propellant, such as a source of ions, from a thruster of the propulsion system. In some embodiments, the application of a voltage potential to the valve may wet a plurality of through holes formed in the valve with the propellant such that the propellant flows through the valve to the thruster. After the valve has been opened, the propulsion system may be operated normally.
FILED	Thursday, May 30, 2019
APPL NO	16/427179
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Spraying Apparatus; Atomising Apparatus; Nozzles B05B 5/1608 (20130101) Producing a Reactive Propulsive Thrust, Not Otherwise Provided for F03H 1/0037 (20130101) Original (OR) Class
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11346356 — Passive bleed valves with adjustable pressure threshold

US 11346356	DeFelice et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Life Cycle Management Center (AFLCMC)
APPLICANT(S)	Hamilton Sundstrand Corporation (Charlotte, North Carolina)
ASSIGNEE(S)	Hamilton Sundstrand Corporation (Charlotte, North Carolina)
INVENTOR(S)	Robert DeFelice (South Windsor, Connecticut); Scott W. Simpson (Easthampton, Massachusetts); Josh Kamp (Glastonbury, Connecticut)
ABSTRACT	A bleed valve includes a housing with an inlet coupled to an outlet by a duct, a guide tube with an orifice fixed in the housing between the inlet and the outlet, a piston, and baffle. The piston is slideably supported on the guide tube and is movable between an open and a closed position, the duct fluidly coupling the inlet and outlet in the open position, the duct fluidly separating the inlet and outlet in the closed position. The orifice fluidly couples the inlet and outlet in the open and closed positions to move piston between the open and closed positions according to differential pressure between the bleed valve inlet and outlet. The baffle is slideably supported by the guide tube to set the differential pressure at which the piston moves between the open and closed positions. Gas turbines and differential pressure adjustment methods are also described.
FILED	Friday, March 05, 2021
APPL NO	17/193235
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/105 (20130101) F01D 17/145 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 6/08 (20130101) F02C 9/18 (20130101) Non-positive-displacement Pumps F04D 27/023 (20130101) F04D 27/0215 (20130101) Original (OR) Class Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 1/126 (20130101) F16K 15/026 (20130101)
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11346820 — HPLC-PDA method and uses thereof in phytoestrogen measurement

US 11346820	Aguirre
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	The Board Of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S)	The Board of Regents of The University of Texas System (Austin, Texas)
INVENTOR(S)	Maria Teresa Aguirre (San Benito, Texas)
ABSTRACT	Presented are improved and more sensitive methods for measuring levels of phytoestrogens in a biological sample, and specifically in a human urine sample, employing a High Pressure Liquid Chromatography method, coupled with a photodiode array analysis detection system. Calibration curve preparation for each of a panel of phytoestrogen analytes, including daidzein, equol and genistein, are provided employing techniques that demonstrate greater accuracy and sensitivity of sample level measurement. Clinically applicable techniques suitable for large population scale screening, diet and gut microflora characterization and disease analysis and correlation in human populations, such as in at risk breast cancer populations, through monitoring of phytoestrogen levels, is disclosed.
FILED	Thursday, December 19, 2019
APPL NO	16/721075
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/06 (20130101) Original (OR) Class G01N 30/74 (20130101) G01N 30/8665 (20130101) G01N 30/8675 (20130101) G01N 2030/027 (20130101)
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11346904 — Methods and apparatus for optically detecting magnetic resonance

US 11346904	Pham et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Office of Scientific Research (AFOSR) Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E) MIT Lincoln Laboratory (MITLL) Federally Funded Research and Development Center (FFRDC) Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Linh M. Pham (Arlington, Massachusetts); Kerry Alexander Johnson (Somerville, Massachusetts); Carson Arthur Teale (Cambridge, Massachusetts); Hannah A. Clevenson (Cambridge, Massachusetts); Danielle Ann Braje (Winchester, Massachusetts); Christopher Michael McNally (Cambridge, Massachusetts); John Francis Barry (Cambridge, Massachusetts)
ABSTRACT	A magnetometer containing a crystal sensor with solid-state defects senses the magnitude and direction of a magnetic field. The solid-state defects in the crystal sensor absorb microwave and optical energy to transition between several energy states while emitting light intensity indicative of their spin states. The magnetic field alters the spin-state transitions of the solid-state defects by amounts depending on the solid-state defects' orientations with respect to the magnetic field. The optical read out, reporting the spin state of an ensemble of solid-state defects from one particular orientation class, can be used to lock microwave signals to the resonances associated with the spin-state transitions. The frequencies of the locked microwave signals can be used to reconstruct the magnetic field vector.
FILED	Monday, July 06, 2020
APPL NO	16/946756
ART UNIT	2858 — Printing/Measuring and Testing
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 24/10 (20130101) G01N 24/12 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/24 (20130101) G01R 33/26 (20130101) Original (OR) Class G01R 33/323 (20130101)
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11347594 — Inter-processor communications fault handling in high performance computing networks

US 11347594	LePera et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Aeronautical Systems Center (ASC) Department of Energy (DOE) National Nuclear Security Administration (NNSA) Advanced Simulation and Computing Program (ASC)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	William P. LePera (Wappingers Falls, New York); Sameh Sherif Sharkawi (Cypress, Texas)
ABSTRACT	A computer-implemented method and system for inter-processor communications fault handling in high performance computing networks. The method includes detecting that an InfiniBand (IB) queue pair has transitioned into an error state based on an unsuccessful completion status that relates to unsuccessful delivery of a message from an initiator endpoint at a first server device to at least one target endpoint at a second server device. The initiator and target endpoints are associated with at least one application under execution. An embodiment includes inferring, when the unsuccessful completion status is indicated as flushed, that the message was in a send queue of the IB queue pair when the IB queue pair transitioned into the error state. An embodiment includes establishing an IB Direct Connect queue pair connection between the target and initiator endpoints. An embodiment includes re-queueing the message in the IB queue pair for dispatch to the target endpoint.
FILED	Tuesday, November 26, 2019
APPL NO	16/695556
ART UNIT	2113 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Electric Digital Data Processing G06F 9/54 (20130101) G06F 11/1438 (20130101) G06F 11/1443 (20130101) Original (OR) Class G06F 11/2023 (20130101) G06F 2209/548 (20130101)
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11347902 — Defensive routing and related techniques

US 11347902	Bush et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E) MIT Lincoln Laboratory (MITLL) Federally Funded Research and Development Center (FFRDC) Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Kevin B. Bush (Sudbury, Massachusetts); Matthew D. Hicks (Blacksburg, Virginia); Timothy D. Trippel (Mishawaka, Indiana)
ABSTRACT	Techniques are disclosed for defensive routing of guard wires for security-critical wires in an integrated circuit (IC). Defensive routing provides a routing-centric and preventive layout-level defense against IC fabrication time attacks against security-critical wires within an IC. An example methodology implementing the techniques includes identifying at least one security-critical wire in an IC design, identifying at least one unblocked surface of the identified at least one security-critical wire, and guarding the identified at least one surface of the identified at least one security-critical wire with a guard wire. In one example, the guard wire may be a natural guard wire. In another example, the guard wire may be a synthetic guard wire.
FILED	Thursday, October 10, 2019
APPL NO	16/598293
ART UNIT	2494 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 21/56 (20130101) G06F 21/70 (20130101) G06F 21/71 (20130101) G06F 21/73 (20130101) G06F 21/86 (20130101) Original (OR) Class G06F 21/87 (20130101) G06F 21/88 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/552 (20130101) H01L 23/576 (20130101) H01L 23/5386 (20130101) H01L 23/49822 (20130101) H01L 23/49838 (20130101) H01L 2224/05568 (20130101) Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 43/28 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/002 (20130101) H04L 29/06877 (20130101) H04L 63/14 (20130101) H04L 63/145 (20130101) H04L 63/1441 (20130101) Telephonic Communication H04M 3/2281 (20130101) Pictorial Communication, e.g Television H04N 21/44236 (20130101) Wireless Communication Networks H04W 12/128 (20210101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 707/952 (20130101)
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11348474 — Automation architecture for compliance with air traffic clearances

US 11348474	Venkataraman et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey)
ASSIGNEE(S)	HONEYWELL INTERNATIONAL INC. (Charlotte, North Carolina)
INVENTOR(S)	Vijay Venkataraman (Excelsior, Minnesota); Benjamin Lee Johnson (Brooklyn Park, Minnesota)
ABSTRACT	An air traffic command automation system for automating the process of listening to, interpreting, adhering to, and responding to air traffic command messages is disclosed. The system includes one or more processors configured by programming instructions on non-transient computer readable media. The system is configured to: receive an air traffic command message, from an entity other than the flight crew, that includes one or more tasks for the aircraft to perform; determine from the command message the one or more tasks for the aircraft to perform; generate a sequence of actions for each task that the aircraft can undertake to accomplish the task; verify the coherence, feasibility, and safety of the actions; relay an interpretation of the command message to the command message originator; preview the verified sequence of actions with the flight crew; and issue commands to execute actions at appropriate points during a mission.
FILED	Wednesday, August 07, 2019
APPL NO	16/534537
ART UNIT	2674 — Facsimile; Printer; Color; halftone; Scanner; Computer Graphic Processing; 3-D Animation; Display Color; Attributes; Object Processing; Hardware and Memory
CURRENT CPC	Electric Digital Data Processing G06F 3/0484 (20130101) Traffic Control Systems G08G 5/0013 (20130101) G08G 5/0026 (20130101) G08G 5/0047 (20130101) Original (OR) Class Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/22 (20130101) G10L 15/1822 (20130101) G10L 2015/223 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/12 (20130101)
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11348998 — Reconfigurable graphene devices via electrical double layer gating

US 11348998	Hayashi et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Information Warfare Center (NIWC) Naval Information Warfare Center Pacific (NIWCPACIFIC)
APPLICANT(S)	United States of America as respresented by the Secretary of the Navy (San Diego, California)
ASSIGNEE(S)	United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Cody K. Hayashi (Waipahu, Hawaii); Richard C. Ordonez (Miliani, Hawaii); David G. Garmire (Ann Arbor, Michigan); Lewis Hsu (Honolulu, Hawaii)
ABSTRACT	A method for using a graphene field-effect transistor (GFET) as a reconfigurable circuit, the method comprising the following steps: depositing a liquid dielectric over a graphene channel of the GFET; applying an activation energy via a first electric field across the liquid dielectric and the graphene channel to electrochemically produce chemical species within the liquid dielectric such that the chemical species accumulate at, and molecularly bond with, the graphene channel thereby decreasing a conductivity of the graphene channel; and applying a deactivation energy via a second electric field of opposite polarity to the first electric field to remove interaction between the chemical species and the graphene channel to increase the conductivity of the graphene channel.
FILED	Monday, April 05, 2021
APPL NO	17/222400
ART UNIT	2897 — Semiconductors/Memory
CURRENT CPC	Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 4/04 (20130101) H01G 7/06 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/0649 (20130101) Original (OR) Class H01L 29/1606 (20130101)
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11349011 — Method of making heteroepitaxial structures and device formed by the method

US 11349011	Brueck et al.
FUNDED BY	Department of Defense (DOD) Defense Threat Reduction Agency (DTRA) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	UNM RAINFOREST INNOVATIONS (Albuquerque, New Mexico)
ASSIGNEE(S)
INVENTOR(S)	Steven R. J. Brueck (Albuquerque, New Mexico); Stephen D. Hersee (Albuquerque, New Mexico); Seung-Chang Lee (Albuquerque, New Mexico); Daniel Feezell (Albuquerque, New Mexico)
ABSTRACT	A method for making a heteroepitaxial layer. The method comprises providing a semiconductor substrate. A seed area delineated with a selective growth mask is formed on the semiconductor substrate. The seed area comprises a first material and has a linear surface dimension of less than 100 nm. A heteroepitaxial layer is grown on the seed area, the heteroepitaxial layer comprising a second material that is different from the first material. Devices made by the method are also disclosed.
FILED	Tuesday, January 21, 2020
APPL NO	16/748361
ART UNIT	2897 — Semiconductors/Memory
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 40/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02107 (20130101) H01L 21/02381 (20130101) H01L 21/02532 (20130101) H01L 21/02538 (20130101) H01L 21/02639 (20130101) H01L 27/1211 (20130101) H01L 29/04 (20130101) H01L 29/16 (20130101) H01L 29/20 (20130101) H01L 29/045 (20130101) H01L 29/0665 (20130101) H01L 29/0673 (20130101) H01L 29/0676 (20130101) H01L 29/775 (20130101) H01L 29/785 (20130101) H01L 29/7783 (20130101) H01L 29/7827 (20130101) H01L 29/7851 (20130101) H01L 29/66462 (20130101) Original (OR) Class H01L 29/66469 (20130101) H01L 29/66666 (20130101) H01L 29/66795 (20130101)
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11349091 — Halide perovskite thin films and methods for production thereof

US 11349091	Yu et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida)
ASSIGNEE(S)	THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida)
INVENTOR(S)	Zhibin Yu (Tallahassee, Florida); Thomas Geske (Tallahassee, Florida)
ABSTRACT	Methods are provided for making halide perovskite thin films. The method may include forming a pattern of islands of a nucleation promoter material onto a substrate; applying onto the substrate and islands a solution which includes a halide perovskite or precursors thereof, to form a coated substrate; and drying the coated substrate to form a crystalline halide perovskite film. Halide perovskite thin films, which may be made by these methods, and LEDs including these films are also provided.
FILED	Friday, May 18, 2018
APPL NO	16/614587
ART UNIT	1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 21/006 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/34 (20130101) C01P 2002/72 (20130101) C01P 2004/03 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0003 (20130101) H01L 51/0096 (20130101) H01L 51/4206 (20130101) Original (OR) Class
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11349186 — Magnetic-free non-reciprocal circuits based on sub-harmonic spatio-temporal conductance modulation

US 11349186	Nagulu et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S)	The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S)	Aravind Nagulu (New York, New York); Harish Krishnaswamy (New York, New York)
ABSTRACT	A circuit comprising a differential transmission line and eight switches provides non-reciprocal signal flow. In some embodiments, the circuit can be driven by four local oscillator signals using a boosting circuit. The circuit can be used to form a gyrator. The circuit can be used to form a circulator. The circuit can be used to form three-port circulator than can provide direction signal flow between a transmitter and an antenna and from the antenna to a receiver. The three-port circulator can be used to implement a full duplex transceiver that uses a single antenna for transmitting and receiving.
FILED	Tuesday, January 21, 2020
APPL NO	17/288155
ART UNIT	2843 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/383 (20130101) Original (OR) Class Demodulation or Transference of Modulation From One Carrier to Another H03D 7/1466 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 5/14 (20130101)
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11349222 — Systems and methods for sensing a lifeform using dynamic metasurface antennas

US 11349222	Faghih Imani et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	Duke University (Durham, North Carolina)
ASSIGNEE(S)	Duke University (Durham, North Carolina)
INVENTOR(S)	Seyedmohammadreza Faghih Imani (Durham, North Carolina); Timothy Sleasman (Durham, North Carolina); Jonah Gollub (Durham, North Carolina); David Smith (Durham, North Carolina)
ABSTRACT	The present disclosure provides systems and methods relating to sensing the presence of a lifeform. In particular, the present disclosure provides systems and methods for detecting the presence of a lifeform in a building or room using dynamic metasurface aperture (DMA), which overcome many limitations of currently available radio frequency (RF) or infrared (IR)-based systems.
FILED	Friday, September 21, 2018
APPL NO	16/138552
ART UNIT	3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/56 (20130101) Antennas, i.e Radio Aerials H01Q 9/30 (20130101) H01Q 15/0086 (20130101) Original (OR) Class
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11349263 — Electromagnetic interference shielding for a coaxial connector using a gasket assembly

US 11349263	Shaw
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Information Warfare Center (NIWC)
APPLICANT(S)	Rockwell Collins, Inc. (Cedar Rapids, Iowa)
ASSIGNEE(S)	Rockwell Collins, Inc. (Cedar Rapids, Iowa)
INVENTOR(S)	Daniel Shaw (Cedar Rapids, Iowa)
ABSTRACT	An electromagnetic interference (EMI) shield system is disclosed. The system may include an EMI gasket assembly configured to prevent radio frequency (RF) radiation from escaping through a gap between a RF connector and the enclosure. The gasket assembly may include a gasket including a receiving portion. The receiving portion may be configured to receive a portion of a shaft of the RF connector. The gasket may be formed of a compressible material. The gasket assembly may include a spacer configured to couple to a portion of the shaft of the RF connector. The spacer may be configured to compress the gasket against a portion of the enclosure when the spacer is rotated in a first direction. The spacer may be configured to provide electrical continuity between the radio frequency connector and the gasket by causing the gasket to form an electrical connection with the enclosure when the gasket is compressed.
FILED	Friday, May 07, 2021
APPL NO	17/314292
ART UNIT	2831 — Electrical Circuits and Systems
CURRENT CPC	Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 13/6584 (20130101) Original (OR) Class H01R 24/54 (20130101) H01R 24/56 (20130101)
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11349276 — Ultra-short pulse mid and long wave infrared laser

US 11349276	Budni et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
ASSIGNEE(S)	BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S)	Peter A. Budni (Nashua, New Hampshire); Alan R. Enman (Merrimack, New Hampshire); Yannick C. Morel (Falls Church, Virginia)
ABSTRACT	The system and method of using an ultra-short pulse mid and long wave infrared laser. The system is seeded with a 2 μm laser source having a pulse duration in the femtosecond range. The beam is stretched, to increase the pulse duration, and the beam is amplified, to increase an energy level of the laser beam. Both mid wave IR and long wave IR seed beams are first generated, and then amplified via one or more optical parametric chirped-pulse amplification stages. A compressor may be used to compress one or more of the output beams to achieve high peak power and controllable pulse duration in the output beams. The output beams may then be used to create atmospheric or material effects at km range.
FILED	Wednesday, December 02, 2020
APPL NO	17/109582
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/11 (20130101) Original (OR) Class H01S 3/0057 (20130101) H01S 3/091 (20130101) H01S 3/0092 (20130101) H01S 3/1024 (20130101) H01S 3/2308 (20130101)
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11349279 — Optically cooled platform for thermal management applications

US 11349279	Osinski et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	STC.UNM (Albuquerque, New Mexico)
ASSIGNEE(S)	UNM Rainforest Innovations (Albuquerque, New Mexico)
INVENTOR(S)	Marek Osinski (Albuquerque, New Mexico); Alexander Neumann (Albuquerque, New Mexico); Gennady A. Smolyakov (Albuquerque, New Mexico)
ABSTRACT	A semiconductor device comprising a waveguide having a core, said core having inserted therein one or more layers of nanoemitters.
FILED	Tuesday, January 28, 2020
APPL NO	16/775200
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0408 (20130101) H01S 5/026 (20130101) H01S 5/341 (20130101) H01S 5/347 (20130101) H01S 5/02469 (20130101) Original (OR) Class H01S 5/3412 (20130101)
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11349480 — Circuits based on magnetoelectric transistor devices

US 11349480	Gaul et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST) Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	Board of Regents of the University of Nebraska (Lincoln, Nebraska)
ASSIGNEE(S)	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska); INTEL CORPORATION (Santa Clara, California)
INVENTOR(S)	Nishtha Sharma Gaul (Richardson, Texas); Andrew Marshall (Dallas, Texas); Peter A. Dowben (Crete, Nebraska); Dmitri E. Nikonov (Beaverton, Oregon)
ABSTRACT	Logic circuits constructed with magnetoelectric (ME) transistors are described herein. A ME logic gate device can include at least one conducting device, for example, at least one MOS transistor; and at least one ME transistor coupled to the at least one conducting device. The ME transistor can be a ME field effect transistor (ME-FET), which can be can be an anti-ferromagnetic spin-orbit read (AFSOR) device or a non-AFSOR device. The gates and logic circuits described herein can be included as standard cells in a design library. Cells of the cell library can include standard cells for a ME inverter device, a ME minority gate device, a ME majority gate device, a ME full adder, a ME XNOR device, a ME XOR device, or a combination thereof.
FILED	Tuesday, September 24, 2019
APPL NO	16/581691
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/42312 (20130101) Pulse Technique H03K 19/10 (20130101) H03K 19/16 (20130101) Original (OR) Class H03K 19/21 (20130101)
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11349581 — Interference monitoring in radio communication systems

US 11349581	Dybdal et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) The Aerospace Corporation (AEROSPACE) Federally Funded Research and Development Center (FFRDC) Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S)	The Aerospace Corporation (El Segundo, California)
ASSIGNEE(S)	THE AEROSPACE CORPORATION (El Segundo, California)
INVENTOR(S)	Robert B. Dybdal (Palos Verdes Estates, California); Catherine A. Allen (Los Angeles, California); Lamont Cooper, Jr. (Fullerton, California)
ABSTRACT	Apparatus and methods for monitoring interference in radio communication systems are provided. In certain embodiments, an interference monitor system for a ground terminal detects for interference based on a sum of the power levels of orthogonal polarizations of detected interference, thereby allowing the total and average peak interference power levels to be obtained independent of interference polarization. Further, the interference can be divided into frequency bins over the received signal bandwidth(s), thereby facilitating measurement of interference spectral characteristics. Multiple interference monitors can be included to detect interference over the full angular range over which potential interference has access as well as to determine an angular direction of the interference.
FILED	Tuesday, January 07, 2020
APPL NO	16/736099
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Transmission H04B 7/10 (20130101) H04B 17/345 (20150115) Original (OR) Class
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11349794 — Scanning tool for detecting sensitive information in text transmissions

US 11349794	Leveille et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Surface Warfare Center (NSWC)
APPLICANT(S)	The United States of America, as represented by the Secretary of the Navy (Crane, Indiana)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Jamie Blaine Leveille (Kennebunk, Maine); Thomas James Tabb (Portsmouth, New Hampshire)
ABSTRACT	The present invention relates to a scanning tool for text transmissions which identifies potentially sensitive text. In exemplary embodiments, a guardian application scans regular email (and calendar appointments) subject, message body, and attachments for key words that identify if a document is potentially sensitive and it notifies the user with specifics if key words are found. If the guardian application cannot scan (either an image or a document with text that cannot be scanned), it notifies the user, requests them to open and review the document, and requires the user to select if they have or have not reviewed the document. It will not send the email if the user selects that they have not reviewed the document.
FILED	Monday, October 05, 2020
APPL NO	17/063202
ART UNIT	2171 — Graphical User Interface and Document Processing
CURRENT CPC	Electric Digital Data Processing G06F 3/04842 (20130101) G06F 16/383 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 51/12 (20130101) Original (OR) Class H04L 51/22 (20130101)
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11349894 — Bandwidth-dependent media stream compression

US 11349894	Mitchell et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Army Medical Research Acquisition Activity (USAMRAA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	Architecture Technology Corporation (Minneapolis, Minnesota)
ASSIGNEE(S)	Architecture Technology Corporation (Minneapolis, Minnesota)
INVENTOR(S)	Tyler J. Mitchell (Ithaca, New York); Scott Aloisio (Willseyville, New York); Matthew A. Stillerman (Ithaca, New York); Valentino Felipe (Campbell, California); Judson Powers (Ithaca, New York)
ABSTRACT	In general, this disclosure describes media stream transmission techniques for a computing device. The computing device captures a first media item and identifies a primary portion of the first media item and a secondary portion of the first media item different than the primary portion. The computing device applies a first compression algorithm to the primary portion of the first media item to generate a compressed primary portion. The computing device applies a second compression algorithm to the secondary portion of the first media item to generate a compressed secondary portion, where a data compression ratio of the second compression algorithm is greater than a data compression ratio of the first compression algorithm. The computing device transmits, to a central computing device, the compressed primary portion of the first media item and the compressed secondary portion of the first media item.
FILED	Thursday, November 19, 2020
APPL NO	16/952981
ART UNIT	2445 — Computer Networks
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 65/601 (20130101) Original (OR) Class H04L 65/607 (20130101) H04L 65/608 (20130101) Pictorial Communication, e.g Television H04N 19/182 (20141101) H04N 19/186 (20141101)
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11350054 — Dual gain imaging digital pixel memory

US 11350054	Hairston
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
ASSIGNEE(S)	BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S)	Allen W. Hairston (Andover, Massachusetts)
ABSTRACT	Techniques and architectures for simultaneous readout and integration of image data from pixels while increasing their sensitivity and reducing required data rates for moving information off of the chip using pixels configured to conduct Analog-to-Digital Conversions (ADCs) of image data, wherein each pixel operates in a rolling Integrate While Read (IWR) mode using SRAM in place of traditional latches for in-pixel storage.
FILED	Thursday, February 06, 2020
APPL NO	16/783492
ART UNIT	2884 — Optics
CURRENT CPC	Systems for Regulating Electric or Magnetic Variables G05F 3/205 (20130101) Static Stores G11C 11/417 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14609 (20130101) Pictorial Communication, e.g Television H04N 5/378 (20130101) Original (OR) Class
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11350382 — Digital buoy systems and methods

US 11350382	Ly et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	United States of America as Represented by The Secretary of The Army (Alexandria, Virginia)
ASSIGNEE(S)	UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia)
INVENTOR(S)	Tung N Ly (Lorton, Virginia); Duane N Morrison (Stafford, Virginia); Denise R LaDue (Louisville, Kentucky)
ABSTRACT	A distributed and buoy tracking and mesh network communication system includes buoy node devices having critical, designated placement determined navigational guidance criteria. Each buoy node apparatus serves a dual navigation and data transmission function.
FILED	Wednesday, March 25, 2020
APPL NO	16/829929
ART UNIT	2645 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC	Ships or Other Waterborne Vessels; Equipment for Shipping B63B 22/16 (20130101) B63B 2203/00 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/51 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/182 (20130101) Wireless Communication Networks H04W 16/26 (20130101) H04W 64/003 (20130101) Original (OR) Class H04W 84/18 (20130101)
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11350490 — Integrated temperature control for multi-layer ceramics and method

US 11350490	Wilson et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Air Systems Command (NAVAIR)
APPLICANT(S)	Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S)	Raytheon Company (Waltham, Massachusetts)
INVENTOR(S)	James S. Wilson (Hurst, Texas); Joshua Lamb (Garland, Texas); Steven P. McFarlane (McKinney, Texas)
ABSTRACT	A multi-layer ceramic module is provided that includes an integrated temperature control and a power switch. The integrated temperature control is configured to dissipate thermal energy. The power switch is configured to couple a power source for a standard component of the multi-layer ceramic module to the integrated temperature control.
FILED	Wednesday, March 08, 2017
APPL NO	15/453269
ART UNIT	3761 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Systems for Controlling or Regulating Non-electric Variables G05D 23/19 (20130101) Electric Digital Data Processing G06F 1/206 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/4857 (20130101) H01L 23/34 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 1/02 (20130101) Original (OR) Class H05B 3/22 (20130101) H05B 3/141 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20 (20130101)
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Department of Energy (DOE)

11344283 — Ultrasound waveform tomography with spatial and edge regularization

US 11344283	Huang et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Congressionally Directed Medical Research Programs (CDMRP) Department of Energy (DOE) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Los Alamos National Laboratory (LANL) Federally Funded Research and Development Center (FFRDC) Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)	Los Alamos National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S)	TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico)
INVENTOR(S)	Lianjie Huang (Los Alamos, New Mexico); Youzuo Lin (Los Alamos, New Mexico)
ABSTRACT	Synthetic-aperture ultrasound tomography systems and methods using scanning arrays and algorithms configured to simultaneously acquire ultrasound transmission and reflection data, and process the data for improved ultrasound tomography imaging, wherein the tomography imaging comprises total-variation regularization, or a modified total variation regularization, particularly with edge-guided or spatially variant regularization.
FILED	Monday, July 23, 2018
APPL NO	16/043071
ART UNIT	3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0073 (20130101) A61B 5/7275 (20130101) A61B 8/13 (20130101) A61B 8/14 (20130101) A61B 8/15 (20130101) A61B 8/085 (20130101) A61B 8/145 (20130101) A61B 8/406 (20130101) A61B 8/483 (20130101) A61B 8/0825 (20130101) A61B 8/4477 (20130101) A61B 8/4488 (20130101) A61B 8/4494 (20130101) A61B 8/5207 (20130101) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 15/8915 (20130101) G01S 15/8929 (20130101) G01S 15/8997 (20130101) Image Data Processing or Generation, in General G06T 5/001 (20130101) G06T 11/005 (20130101)
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11344850 — Nanocomposite membranes and methods of forming the same

US 11344850	Tsapatsis et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	Michael Tsapatsis (Baltimore, Maryland); Xiaoli Ma (Pleasant Prairie, Wisconsin)
ASSIGNEE(S)	Michael Tsapatsis (Baltimore, Maryland); Xiaoli Ma (Pleasant Prairie, Wisconsin)
INVENTOR(S)	Michael Tsapatsis (Baltimore, Maryland); Xiaoli Ma (Pleasant Prairie, Wisconsin)
ABSTRACT	A nanocomposite including a mesoporous, macroporous, or a combination thereof oxide and a zeolitic imidazolate framework (ZIF) that is filling the pores of the oxide to form a ZIF phase embedded and at least substantially confined mostly within the oxide. Methods of making nanocomposites including the steps of depositing an oxide in the pores of a mesoporous oxide; and further treating the resulting material with vapor, liquid, or supercritical CO₂comprising an azole-based compound, a carboxylate based compound, or a combination thereof. Use of disclosed articles to separate propylene and propane in a mixture thereof.
FILED	Friday, October 26, 2018
APPL NO	16/172581
ART UNIT	1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 53/228 (20130101) B01D 67/0072 (20130101) B01D 67/0079 (20130101) B01D 69/02 (20130101) B01D 69/08 (20130101) B01D 69/10 (20130101) B01D 69/147 (20130101) B01D 69/148 (20130101) Original (OR) Class B01D 71/06 (20130101) B01D 71/025 (20130101) B01D 71/028 (20130101) B01D 2256/24 (20130101) B01D 2257/7022 (20130101) B01D 2325/20 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/40 (20130101) C23C 16/045 (20130101) C23C 16/56 (20130101) C23C 16/407 (20130101) C23C 16/45525 (20130101) C23C 16/45555 (20130101)
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11345067 — Mechanical reticulation of polymeric-based closed cell foams

US 11345067	Rodriguez et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California); The Texas A and M University System (College Station, Texas)
ASSIGNEE(S)	LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California); THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas)
INVENTOR(S)	Jennifer N. Rodriguez (Lathrop, California); Duncan J. Maitland (College Station, Texas); Thomas S. Wilson (San Leandro, California)
ABSTRACT	Polymeric based closed cell foams, such as shape memory polymer foams, contain bubbles. Making these bubbles continuous is called reticulation. Disclosed are embodiments of a device and method to controllably reticulate polymer-based closed cell foams by puncturing the membranes of these polymer-based closed cell foams.
FILED	Friday, May 08, 2020
APPL NO	16/870094
ART UNIT	1788 — Miscellaneous Articles, Stock Material
CURRENT CPC	Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/06 (20130101) A61L 31/06 (20130101) A61L 31/146 (20130101) A61L 2400/16 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 44/5663 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2075/00 (20130101) B29K 2105/046 (20130101) B29K 2995/0093 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/18 (20130101) B32B 5/32 (20130101) B32B 2266/08 (20130101) B32B 2266/0278 (20130101) B32B 2535/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/73 (20130101) C08G 18/3228 (20130101) C08G 18/3278 (20130101) C08G 18/3284 (20130101) C08G 2101/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/38 (20130101) C08J 2205/052 (20130101) C08J 2207/10 (20130101) C08J 2375/04 (20130101) Compositions of Macromolecular Compounds C08L 75/04 (20130101) C08L 75/04 (20130101) C08L 2201/12 (20130101) C08L 2203/14 (20130101)
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11345595 — System and methods for fabricating boron nitride nanostructures

US 11345595	Fathalizadeh et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Aidin Fathalizadeh (Berkeley, California); Thang Pham (Berkeley, California); William Mickelson (Albany, California); Alexander Zettl (Kensington, California)
ABSTRACT	This disclosure provides systems, methods, and apparatus related to boron nitride nanomaterials. In one aspect, a method includes generating a directed flow of plasma. A boron-containing species is introduced to the directed flow of the plasma. Boron nitride nanostructures are formed in a chamber. In another aspect, a method includes generating a directed flow of plasma using nitrogen gas. A boron-containing species is introduced to the directed flow of the plasma. The boron-containing species can consist of boron powder, boron nitride powder, and/or boron oxide powder. Boron nitride nanostructures are formed in a chamber, with a pressure in the chamber being about 3 atmospheres or greater.
FILED	Wednesday, June 24, 2015
APPL NO	15/321177
ART UNIT	1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/08 (20130101) B01J 2219/0879 (20130101) B01J 2219/0894 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 21/064 (20130101) C01B 21/0641 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/82 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101) C01P 2004/13 (20130101) C01P 2004/24 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/583 (20130101) C04B 35/622 (20130101) C04B 2235/95 (20130101) C04B 2235/767 (20130101) C04B 2235/5276 (20130101) C04B 2235/5284 (20130101) C04B 2235/5454 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/762 (20130101) Y10S 977/896 (20130101)
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11345771 — Compositions and methods of promoting organic photocatalysis

US 11345771	Miyake et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado); COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colorado)
ASSIGNEE(S)	The Regents of the University of Colorado (Denver, Colorado); Colorado State University Research Foundation (Fort Collins, Colorado)
INVENTOR(S)	Garret Miyake (Fort Collins, Colorado); Jordan Corinne Theriot (Denver, Colorado); Matthew D. Ryan (Longmont, Colorado); Ryan Michael Pearson (Fort Collins, Colorado); Tracy Allen French (Fircrest, Washington); Haishen Yang (Shanghai, China PRC); Andrew Lockwood (Kent, United Kingdom); Charles Musgrave (Longmont, Colorado); Chern-Hooi Lim (Boulder, Colorado); Ya Du (Shanghai, China PRC); Blaine McCarthy (Fort Collins, Colorado)
ABSTRACT	The invention provides novel compounds and methods that are useful in promoting reactions that proceed through an oxidative quenching pathway. In certain embodiments, the reactions comprise atom transfer radical polymerization.
FILED	Tuesday, March 02, 2021
APPL NO	17/190110
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/0244 (20130101) B01J 2231/12 (20130101) B01J 2231/42 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 37/02 (20130101) C07B 39/00 (20130101) C07B 41/00 (20130101) C07B 43/00 (20130101) C07B 45/00 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 2/48 (20130101) C08F 2/50 (20130101) C08F 4/40 (20130101) C08F 20/14 (20130101) C08F 212/08 (20130101) C08F 218/08 (20130101) C08F 220/14 (20130101) C08F 220/22 (20130101) C08F 220/44 (20130101) C08F 220/285 (20200201) C08F 220/1804 (20200201) C08F 220/1807 (20200201) C08F 220/1811 (20200201) Original (OR) Class C08F 230/085 (20200201) C08F 2438/01 (20130101)
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11345786 — Liquid bicontinuous stabilized assemblies by interfacial jamming of nanoparticles

US 11345786	Huang et al.
FUNDED BY	Department of Energy (DOE) Basic Energy Sciences (BES) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA Materials Sciences and Engineering Division (MSE)
APPLICANT(S)	THE UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts); The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	THE UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Caili Huang (Oak Ridge, Tennessee); Joseph William Forth (Ilkley, United Kingdom); Brett Anthony Helms (Oakland, California); Thomas P. Russell (Amherst, Massachusetts)
ABSTRACT	A method for preparing a stabilized assembly includes combining a first liquid phase including nanoparticles and a second, immiscible liquid phase, dissolving in the second phase a first end-functionalized polymer having a first molecular weight, and a second end-functionalized polymer having a second molecular weight, wherein the second molecular weight is greater than the first molecular weight, applying a shearing external deformation field to increase the surface area of the first phase to create a new interface, wherein the nanoparticle surfactants form a disordered, jammed assembly at the new interface, and releasing the shearing external deformation field. The polymer and the nanoparticles can interact at an interface through ligand interactions to form nanoparticle surfactants and upon releasing the external deformation field the jammed assembly at the new interface traps the first phase in a deformed state having the first liquid phase and the second liquid phase as interpenetrating domains.
FILED	Friday, May 31, 2019
APPL NO	16/428536
ART UNIT	1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 23/4105 (20220101) B01F 23/4146 (20220101) B01F 25/10 (20220101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/11 (20130101) Original (OR) Class C08J 3/203 (20130101) C08J 2325/06 (20130101) C08J 2383/08 (20130101) C08J 2425/06 (20130101) C08J 2483/08 (20130101) Compositions of Macromolecular Compounds C08L 25/06 (20130101) C08L 83/08 (20130101)
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11345879 — Emulsion stereolithography and 3D printing of multimaterials and nanoscale material gradients

US 11345879	Zheng et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Xiaoyu Zheng (Pleasanton, California); Joshua R. Deotte (Livermore, California)
ABSTRACT	A functionally graded material is formed by pipetting individual micro-or-nano-litter droplets with a variety of materials including multi-nanostructured material (nanowires, carbon nanotubes, enzymes, multi-element and/or multi-color, multi-biomolecules) and UV polymerization of the flat hydrogel meniscus surface formed at the carrier fluid interface. After step-by-step droplet pipetting and subsequent layer-by-layer UV polymerization via a digital mask, the complete fabricated part without supporting layers is taken out of the carrier fluid while the un-cured micro-litter residue is conveniently suctioned out of the carrier fluid.
FILED	Tuesday, November 17, 2015
APPL NO	14/943873
ART UNIT	1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/20 (20170801) B29C 64/135 (20170801) B29C 64/386 (20170801) B29C 2035/0827 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2105/0061 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/34 (20130101) B29L 2031/7532 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) Original (OR) Class C12M 25/14 (20130101) C12M 35/08 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) C12N 5/0697 (20130101)
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11345938 — Genetically modified cells that produce C6-C10 fatty acid derivatives

US 11345938	Liao et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	CARGILL, INCORPORATED (Wayzata, Minnesota)
ASSIGNEE(S)	CARGILL, INCORPORATED (Wayzata, Minnesota)
INVENTOR(S)	Hans H. Liao (Plymouth, Minnesota); Catherine Bradshaw Poor (Plymouth, Minnesota); Travis Robert Wolter (Plymouth, Minnesota); Michael Tai Man Louie (Plymouth, Minnesota); Erin Kathleen Marasco (Plymouth, Minnesota); Ana Negrete-Raymond (Plymouth, Minnesota)
ABSTRACT	Genes encoding mutant 3-ketoacyl-CoA synthases are introduced into host cells. Certain of the mutants enhance the production of shorter-chain fatty acids and derivatives by the cell than do the wild-type (unmutated) enzymes. In other cases, the chain length is not significantly affected, but productivity is enhanced. In specific cases, both a shift toward lower chain length and higher productivity is seen. Cells producing the mutant 3-ketoacyl-CoA synthases are especially suitable for producing C6-C10 fatty acids and derivatives.
FILED	Thursday, February 01, 2018
APPL NO	16/482569
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 9/1029 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/6409 (20130101) C12P 7/6436 (20130101) Original (OR) Class Enzymes C12Y 203/01199 (20150701)
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11345950 — Probe for selectively characterizing enzymes involved in xenobiotic metabolism and method of making and using the same

US 11345950	Wright et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Pacific Northwest National Laboratory (PNNL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S)	Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S)	Battelle Memorial Institute (Richland, Washington)
INVENTOR(S)	Aaron T. Wright (Richland, Washington); Susan Ramos-Hunter (Kennewick, Washington); Christopher Whidbey (Seattle, Washington)
ABSTRACT	Activity-based probes that can be used to selectively identify and characterize enzymes that are involved in different phases of xenobiotic metabolism in a host and its microbiota population(s) are described. The activity-based probes described specifically label only their target active enzymes involved in xenobiotic metabolism and therefore provide a measurement of true protein functional activity rather than transcript or protein abundance. The activity-based probes also provide multimodal profiling of these active enzymes. Methods for preparing the activity based probes and exemplary methods for their use also are disclosed.
FILED	Wednesday, October 03, 2018
APPL NO	16/151170
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 203/04 (20130101) C07C 233/20 (20130101) C07C 233/33 (20130101) C07C 247/00 (20130101) C07C 247/12 (20130101) C07C 271/28 (20130101) C07C 305/22 (20130101) C07C 317/40 (20130101) Heterocyclic Compounds C07D 203/26 (20130101) C07D 311/16 (20130101) C07D 405/04 (20130101) C07D 405/12 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/203 (20130101) C07H 19/067 (20130101) Peptides C07K 1/13 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/34 (20130101) C12Q 1/48 (20130101) C12Q 1/6837 (20130101) Original (OR) Class C12Q 1/6841 (20130101) C12Q 2565/514 (20130101) C12Q 2600/106 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/583 (20130101) G01N 2333/91177 (20130101)
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11346006 — Rare-earth doped thermal barrier coating bond coat for thermally grown oxide luminescence sensing

US 11346006	Fouliard et al.
FUNDED BY	Department of Energy (DOE) Office of Fossil Energy and Carbon Management (FECM) National Energy Technology Laboratory (NETL)
APPLICANT(S)	UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida)
ASSIGNEE(S)	UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida)
INVENTOR(S)	Quentin Fouliard (Winter Park, Florida); Ranajay Ghosh (Oviedo, Florida); Seetha Raghavan (Oviedo, Florida)
ABSTRACT	A thermal barrier coated component, such as a turbine blade formed from a superalloy substrate, includes a thermal barrier coating applied onto the substrate. A metallic bond coat layer is on the substrate and includes rare-earth luminescent dopants. A ceramic top coat layer is on the bond coat layer. A temperature sensing thermally grown oxide (TGO) layer is formed at the interface of the bond coat layer and ceramic top coat layer. The temperature sensing TGO layer includes grown rare-earth luminescent ions migrated from the metallic bond coat layer in an amount sufficient to enable luminescence sensing of the TGO layer for real-time phosphor thermometry temperature measurements at the TGO layer.
FILED	Monday, September 28, 2020
APPL NO	17/034065
ART UNIT	1715 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/7783 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 28/321 (20130101) C23C 28/3455 (20130101) Original (OR) Class Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/20 (20130101)
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11346335 — Flexible supply gas routing for gas compressors

US 11346335	Echter et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	ONBOARD DYNAMICS LLC (Bend, Oregon)
ASSIGNEE(S)	Onboard Dynamics LLC (Bend, Oregon)
INVENTOR(S)	Nicholas Paul Echter (Fort Collins, Colorado); Kristina Weyer-Geigel (Yakima, Washington)
ABSTRACT	Most multistage compressors specify a maximum inlet pressure that may be supplied to the compressor to stay within designed limits. If the supply gas to be compressed is at a higher pressure than the specified maximum inlet pressure, then its pressure must be reduced before connecting it to the compressor. This pressure reduction is inefficient. The present invention avoids reducing the inlet pressure by routing the supply gas directly to the appropriate compression stage depending on its inlet pressure such that the compressor loads are still within the specified limits of the equipment.
FILED	Monday, May 21, 2018
APPL NO	16/611835
ART UNIT	3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Positive-displacement Machines for Liquids; Pumps F04B 25/00 (20130101) F04B 27/00 (20130101) F04B 27/24 (20130101) F04B 35/002 (20130101) F04B 39/10 (20130101) F04B 41/04 (20130101) F04B 49/002 (20130101) F04B 49/007 (20130101) Original (OR) Class F04B 49/24 (20130101) F04B 49/035 (20130101)
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11346585 — Advanced metal hydride heat transfer system utilizing an electrochemical hydrogen compressor

US 11346585	Bahar et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) Office of Science (DOE-SC)
APPLICANT(S)	Xergy Inc. (Georgetown, Delaware)
ASSIGNEE(S)
INVENTOR(S)	Bamdad Bahar (Georgetown, Delaware); William Parmelee (Seaford, Delaware)
ABSTRACT	An electrochemical heat transfer device utilizes an electrochemical hydrogen compressor to pump hydrogen into and out of a reservoir having a metal hydride forming alloy therein. The absorption of hydrogen by the metal hydride forming alloy is exothermic, produces heat, and the desorption of the hydrogen from the metal hydride forming alloy is endothermic and draws heat in. An electrochemical hydrogen compressor may be configured between to reservoirs and pump hydrogen back and forth to form a heat transfer device. A heat exchange device may be coupled with the reservoir or may comprise the outer surface of the reservoir to transfer heat to an object or to the surroundings. A closed loop may be configured having two reservoirs and one or two electrochemical hydrogen compressors to pump the hydrogen in a loop around the system.
FILED	Wednesday, January 11, 2017
APPL NO	15/403299
ART UNIT	3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 11/005 (20130101) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 17/12 (20130101) Original (OR) Class F25B 25/02 (20130101) F25B 35/04 (20130101) F25B 2500/18 (20130101) Technologies for Adaptation to Climate Change Y02A 30/27 (20180101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 30/62 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/32 (20130101)
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11346702 — Methods and apparatus for calibration and response time testing of level sensors

US 11346702	Hashemian
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	ANALYSIS AND MEASUREMENT SERVICES CORPORATION (Knoxville, Tennessee)
ASSIGNEE(S)	Analysis and Measurement Services Corporation (Knoxville, Tennessee)
INVENTOR(S)	Alexander Hashem Hashemian (Knoxville, Tennessee)
ABSTRACT	Systems and methods of diagnosing performance of a level sensor of a fluid test chamber, including a data acquisition and processing unit configured to receive output signals of one or more level sensors that are installed to a fluid chamber, the data acquisition and processing unit being configured to connect to the one or more level sensors to record and process the output signals to test operation of the one or more level sensors.
FILED	Wednesday, June 24, 2020
APPL NO	16/911054
ART UNIT	2852 — Printing/Measuring and Testing
CURRENT CPC	Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 23/16 (20130101) G01F 25/20 (20220101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/30 (20130101)
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11346993 — Micro-lensed fiber optic plate and methods of forming thereof

US 11346993	Bagwell et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Brett Bagwell (Albuquerque, New Mexico); Jeremy Benjamin Wright (Albuquerque, New Mexico); Jayson Briscoe (Albuquerque, New Mexico); Erika C. Vreeland (Albuquerque, New Mexico)
ABSTRACT	A method of forming a micro-lensed fiber optic plate. The method includes obtaining a fiber optic plate that has a plurality of fibers arranged in parallel. A first end of a fiber of the plurality of fibers can have a first numerical aperture. The fiber of the plurality of fibers includes a core material running along a length of the fiber that is circumscribed by a layer of cladding material. The method also includes creating a lensed surface at a second end of the fiber of the plurality of fibers. The second end is opposite the first end. The lensed surface of the fiber of the plurality of fibers can have a second numerical aperture that is different from the first numerical aperture.
FILED	Tuesday, April 13, 2021
APPL NO	17/228957
ART UNIT	2879 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 6/003 (20130101) Original (OR) Class G02B 6/08 (20130101) G02B 6/3692 (20130101)
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11347594 — Inter-processor communications fault handling in high performance computing networks

US 11347594	LePera et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Aeronautical Systems Center (ASC) Department of Energy (DOE) National Nuclear Security Administration (NNSA) Advanced Simulation and Computing Program (ASC)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	William P. LePera (Wappingers Falls, New York); Sameh Sherif Sharkawi (Cypress, Texas)
ABSTRACT	A computer-implemented method and system for inter-processor communications fault handling in high performance computing networks. The method includes detecting that an InfiniBand (IB) queue pair has transitioned into an error state based on an unsuccessful completion status that relates to unsuccessful delivery of a message from an initiator endpoint at a first server device to at least one target endpoint at a second server device. The initiator and target endpoints are associated with at least one application under execution. An embodiment includes inferring, when the unsuccessful completion status is indicated as flushed, that the message was in a send queue of the IB queue pair when the IB queue pair transitioned into the error state. An embodiment includes establishing an IB Direct Connect queue pair connection between the target and initiator endpoints. An embodiment includes re-queueing the message in the IB queue pair for dispatch to the target endpoint.
FILED	Tuesday, November 26, 2019
APPL NO	16/695556
ART UNIT	2113 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Electric Digital Data Processing G06F 9/54 (20130101) G06F 11/1438 (20130101) G06F 11/1443 (20130101) Original (OR) Class G06F 11/2023 (20130101) G06F 2209/548 (20130101)
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11347866 — Cybersecurity assessment and risk management tool

US 11347866	Gourisetti et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Pacific Northwest National Laboratory (PNNL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S)	Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S)	Battelle Memorial Institute (Richland, Washington)
INVENTOR(S)	Sri Nikhil Gupta Gourisetti (Richland, Washington); Michael E. Mylrea (Alexandria, Virginia); Paul M. Skare (Richland, Washington)
ABSTRACT	Techniques and apparatuses are described for a cybersecurity risk management tool to assess cybersecurity risk and prioritize cybersecurity correction plans. The cybersecurity risk management tool categorizes cybersecurity framework security controls into maturity indicator levels, identifies implementation states achieved by an entity with respect to the cybersecurity framework security controls, and determines which of the maturity indicator levels represents the implementation state achieved by the entity with respect to each of the cybersecurity framework security controls. A cost-benefit analysis for modifying from the implementation state achieved by the entity to a next implementation state to be achieved by the entity with respect to the cybersecurity framework security controls is also enabled. The cost-benefit analysis leverages factored weights including aspects indicative of security perspectives, Gaussian distributions, and the maturity indicator levels.
FILED	Monday, February 03, 2020
APPL NO	16/780672
ART UNIT	2436 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 21/577 (20130101) Original (OR) Class G06F 2221/034 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1433 (20130101)
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11347901 — Frangible security device

US 11347901	DiMaio et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Office of Science (DOE-SC)
APPLICANT(S)	Tetramer Technologies, LLC (Pendleton, South Carolina)
ASSIGNEE(S)	Tetramer Technologies, LLC (Pendleton, South Carolina)
INVENTOR(S)	Jeffrey R. DiMaio (Pendleton, South Carolina); Zachary Hunt (Simpsonville, South Carolina); Yanina Breakiron (Clemson, South Carolina); Baris Kokuoz (Anderson, South Carolina); Bogdan Zdyrko (Clemson, South Carolina); Michael A. Schreuder (Anderson, South Carolina); Stephen D. Hudson (Westminster, South Carolina)
ABSTRACT	The present disclosure pertains to a tamper indicating security device, which indicates unauthorized duplication of and/or access to a variety of secure documents, technologies, products, and/or protected volumes.
FILED	Thursday, June 28, 2018
APPL NO	16/021185
ART UNIT	1785 — Miscellaneous Articles, Stock Material
CURRENT CPC	Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 27/08 (20130101) B32B 27/304 (20130101) B32B 2250/04 (20130101) B32B 2255/26 (20130101) B32B 2305/72 (20130101) B32B 2305/347 (20130101) B32B 2307/412 (20130101) Electric Digital Data Processing G06F 21/34 (20130101) G06F 21/73 (20130101) G06F 21/86 (20130101) Original (OR) Class G06F 21/88 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3278 (20130101)
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11347907 — Systems and methods for distributed power system model calibration

US 11347907	Wang et al.
FUNDED BY	Department of Energy (DOE) Office of Electricity (DOE-OE)
APPLICANT(S)	General Electric Company (Schenectady, New York)
ASSIGNEE(S)	GENERAL ELECTRIC COMPANY (Schenectady, New York)
INVENTOR(S)	Honggang Wang (Clifton Park, New York); Yuh-Shyang Wang (Schenectady, New York); Junqiang Zhou (San Jose, California); Pengyuan Wang (Niskayuna, New York)
ABSTRACT	A computing device for distributed power system model calibration is provided. The computing device is programmed to receive event data and model response data associated with a model to simulate, wherein the model includes a plurality of parameters, divide the event data into a plurality of sets, wherein each set includes associated parameters, and transmit the plurality of sets of event data to a plurality of client nodes. Each client node of the plurality of client nodes is programmed to analyze a corresponding set of event data to determine updated parameters for the model. The computing device is further programmed to receive a plurality of updated parameters for the model from the plurality of client nodes and analyze the received plurality of updated parameters to determine at least one adjusted parameter.
FILED	Thursday, November 21, 2019
APPL NO	16/690965
ART UNIT	2148 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 7/58 (20130101) G06F 17/14 (20130101) G06F 30/18 (20200101) G06F 30/20 (20200101) Original (OR) Class G06F 2111/02 (20200101) G06F 2111/10 (20200101) G06F 2113/04 (20200101) G06F 2119/06 (20200101) Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/06 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/003 (20200101) H02J 3/008 (20130101) H02J 2203/20 (20200101)
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11348702 — System, emanation generator, and process for production of high-purity therapeutic radioisotopes

US 11348702	O'Hara
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Pacific Northwest National Laboratory (PNNL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S)	BATTELLE MEMORIAL INSTITUTE (Richland, Washington)
ASSIGNEE(S)	Battelle Memorial Institute (Richland, Washington)
INVENTOR(S)	Matthew J. O'Hara (Richland, Washington)
ABSTRACT	An isotope production system, emanation generator, and process are disclosed for production of high-purity radioisotopes. In one implementation example, high-purity Pb-212 and/or Bi-212 isotopes are produced suitable for therapeutic applications. In one embodiment the process includes transporting gaseous radon-220 from a radium-224 bearing generator which provides gas-phase separation of the Rn-220 from the Ra-224 in the generator. Subsequent decay of the captured Rn-220 accumulates high-purity Pb-212 and/or Bi-212 isotopes suitable for direct therapeutic applications. Other high-purity product isotopes may also be prepared.
FILED	Friday, August 11, 2017
APPL NO	15/675529
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 51/00 (20130101) A61K 51/1289 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/06 (20130101) Non-metallic Elements; Compounds Thereof; C01B 23/0073 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 21/00 (20130101) Conversion of Chemical Elements; Radioactive Sources G21G 1/0005 (20130101) G21G 4/08 (20130101) Original (OR) Class G21G 4/10 (20130101) G21G 2001/0084 (20130101) G21G 2001/0094 (20130101)
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11348703 — Tunable side-bounce x-ray monochromator

US 11348703	Hong et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)	UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S)	UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S)	Hawoong Hong (Naperville, Illinois); Jonathan Z. Tischler (Lisle, Illinois); Xianbo Shi (Naperville, Illinois)
ABSTRACT	Monochromators selectively transmit a narrow band of wavelengths of radiation from a broader band of wavelengths for use in a variety of applications and industries. Disclosed is a method and system for fixed-exit angle tunable monochromator. The system includes a first diffraction element configured to reflect an input beam incident on a surface of the first diffraction element. The input beam has an input beam vector and the first diffraction element is rotatable about the input beam vector. The system further includes a second diffraction element configured to reflect the beam as an output beam having a fixed beam exit angle. The beam is incident on a surface of the second diffraction element and the reflected beam has a reflected beam vector. The second diffraction element is rotatable about both the input beam vector and the reflected beam vector.
FILED	Wednesday, September 16, 2020
APPL NO	17/022831
ART UNIT	2884 — Optics
CURRENT CPC	Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/062 (20130101) Original (OR) Class
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11349039 — Axially-integrated epitaxially-grown tandem wire arrays

US 11349039	Lewis et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Joint Center for Artificial Photosynthesis (JCAP)
APPLICANT(S)	California Institute of Technology (Pasadena, California)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California)
INVENTOR(S)	Nathan S. Lewis (La Canada Flintridge, California); Shu Hu (Pasadena, California)
ABSTRACT	A photoelectrode, methods of making and using, including systems for water-splitting are provided. The photoelectrode can be a semiconducting material having a photocatalyst such as nickel or nickel-molybdenum coated on the material. The photoelectrode includes an elongated axially integrated wire having at least two different wire compositions.
FILED	Thursday, September 13, 2018
APPL NO	16/130157
ART UNIT	1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Non-metallic Elements; Compounds Thereof; C01B 13/0207 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/55 (20210101) C25B 9/19 (20210101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/078 (20130101) H01L 31/0687 (20130101) H01L 31/1804 (20130101) H01L 31/1892 (20130101) H01L 31/03529 (20130101) H01L 31/035236 (20130101) Original (OR) Class H01L 31/035281 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/544 (20130101) Y02E 10/547 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/50 (20151101)
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11349099 — Method of fabricating a light emitting device having a polymer film with a specified surface rouggness

US 11349099	Qu et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S)	The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S)	Yue Qu (Ann Arbor, Michigan); Xiaheng Huang (Ann Arbor, Michigan); Stephen R. Forrest (Ann Arbor, Michigan)
ABSTRACT	A method of fabricating a light emitting device comprises providing a mold having an unpolished surface with an arithmetic mean roughness R_ain a range from 0.1 μm to 10 μm, depositing a thin polymer film over the surface of the mold, wherein the film has a thickness in a range from 1 μm to 100 μm, positioning a light emitting body onto the thin polymer film, wherein the light emitting body includes an anode, a cathode, and a light emitting layer positioned between the anode and the cathode, and separating the thin polymer film with the light emitting body from the mold. A light emitting device is also described.
FILED	Friday, January 24, 2020
APPL NO	16/752553
ART UNIT	2814 — Semiconductors/Memory
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 41/02 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/3475 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/003 (20130101) H01L 51/56 (20130101) H01L 51/0097 (20130101) H01L 51/5016 (20130101) H01L 51/5268 (20130101) Original (OR) Class H01L 2251/105 (20130101) H01L 2251/5338 (20130101)
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11349117 — Magnetite (Fe₃O₄)—multiwalled carbon nanotube composite structures with performance as high rate electrode materials for Li-ion batteries

US 11349117	Wong et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	The Research Foundation for The State University of New York (Albany, New York)
ASSIGNEE(S)	The Research Foundation for the State University of New York (Albany, New York)
INVENTOR(S)	Stanislaus Wong (Upton, New York); Lei Wang (Port Jefferson, New York); Coray McBean (Malverne, New York); Amy C. Marschilok (Stony Brook, New York); Kenneth Takeuchi (Stony Brook, New York); Esther S. Takeuchi (Stony Brook, New York)
ABSTRACT	A method of synthesizing an electrode material for lithium ion batteries from Fe₃O₄nanoparticles and multiwalled carbon nanotubes (MWNTs) to yield (Fe₃O₄-NWNTs) composite heterostructures. The method includes linking the Fe₃O₄nanoparticles and multiwalled carbon nanotubes using a π-π interaction synthesis process to yield the composite heterostructure electrode material. Since Fe₃O₄has an intermediate voltage, it can be considered an anode (when paired with a higher voltage material) or a cathode (when paired with a lower voltage material).
FILED	Thursday, January 17, 2019
APPL NO	16/250838
ART UNIT	1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/364 (20130101) Original (OR) Class H01M 4/366 (20130101) H01M 4/485 (20130101) H01M 4/523 (20130101) H01M 4/587 (20130101) H01M 10/0525 (20130101) H01M 2004/021 (20130101) H01M 2004/027 (20130101)
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11349118 — Tangent gradient concentration material for battery, digital gradient concentration material for battery

US 11349118	Shin et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)	UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S)	UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S)	YoungHo Shin (LaGrange Highlands, Illinois); Gregory K. Krumdick (Homer Glen, Illinois)
ABSTRACT	The invention provides a cathode active material having a discrete change in concentrations of a first base region and a second pulse region. Also provided is a method for preparing a cathode active material, the method having the steps: supplying chelating agent, aqueous basic solution and a first aqueous metal salt solution to a reactor to create a base region; supplying a second aqueous metal-salt solution to a reactor to form a pulse region, wherein the second aqueous metal-salt solution is intermittently or continuously added during or after the creation of the base region; thermally treating the base region and the pulse region to create active metal precursors; mixing the precursors with lithium salt to produce a mixture; and thermally treating the mixture.
FILED	Monday, September 24, 2018
APPL NO	16/140234
ART UNIT	1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/366 (20130101) Original (OR) Class H01M 4/0471 (20130101) H01M 4/485 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 10/0525 (20130101) H01M 2004/021 (20130101)
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11349149 — Solid electrolyte material and solid-state battery made therewith

US 11349149	Francisco et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	Solid Power, Inc. (Louisville, Colorado)
ASSIGNEE(S)	Solid Power Operating, Inc. (Louisville, Colorado)
INVENTOR(S)	Brian E. Francisco (Superior, Colorado); Heather A. S. Platt (Golden, Colorado); Collin R. Becker (Boulder, Colorado); Joshua Buettner-Garrett (Arvada, Colorado)
ABSTRACT	A solid electrolyte material comprises Li, T, X and A wherein T is at least one of P, As, Si, Ge, Al, and B; X is one or more halogens or N; A is one or more of S and Se. The solid electrolyte material has peaks at 17.8°±0.75° and 19.2°±0.75° in X-ray diffraction measurement with Cu-Kα(1,2)=1.5418 Å and may include glass ceramic and/or mixed crystalline phases.
FILED	Tuesday, March 27, 2018
APPL NO	16/497324
ART UNIT	1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/052 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2300/0068 (20130101)
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11350524 — Conductive trace interconnection tape

US 11350524	Hatch et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Kansas City National Security Campus (KCNSC) NNSA Critical Mission Site Operated by Honeywell Federal Manufacturing & Technologies, LLC (FM&T) at Kansas City, MO
APPLICANT(S)	Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
ASSIGNEE(S)	Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
INVENTOR(S)	Stephen McGarry Hatch (Blue Springs, Missouri); Jonathan Douglas Hatch (Cleveland, Missouri)
ABSTRACT	A conductive trace interconnect tape for use with a printed circuit board or a flexible circuit substrate comprises a top insulating layer, an electrically conductive layer, and a bottom insulating layer. The top insulating layer is formed from electrically insulating material and is configured to provide electrical isolation from electrically conductive objects that are positioned on top of the conductive trace interconnect tape. The electrically conductive layer is positioned underneath the top insulating layer. The electrically conductive layer is formed from electrically conductive material and includes electrical interconnect traces, electrical component pads, or electrically conductive planar portions. The bottom insulating layer is positioned underneath the electrically conductive layer. The bottom insulating layer is formed from electrically insulating material and is configured to provide electrical isolation from electrically conductive objects that are positioned on the printed circuit board or flexible circuit substrate.
FILED	Monday, October 12, 2020
APPL NO	17/067901
ART UNIT	2847 — Electrical Circuits and Systems
CURRENT CPC	Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/09 (20130101) Original (OR) Class H05K 1/118 (20130101) H05K 1/189 (20130101) H05K 1/0393 (20130101) H05K 3/103 (20130101) H05K 2201/05 (20130101) H05K 2201/0335 (20130101) H05K 2201/1028 (20130101)
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National Science Foundation (NSF)

11344237 — Epidermal sensor system and process

US 11344237	Lu et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S)	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S)	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S)	Nanshu Lu (Austin, Texas); Shixuan Yang (Austin, Texas); Pulin Wang (Austin, Texas)
ABSTRACT	Epidermal electronics are sensors with mechanical properties matching human epidermis. Their manufacturing process includes photolithography and dry and wet etching within cleanroom facilities. The high cost of manpower, materials, photo masks, and facilities greatly hinders the commercialization potential of disposable epidermal electronics. In contrast, an embodiment of the invention includes a low cost, high throughput, bench top “cut-and-paste” method to complete the freeform manufacture of epidermal sensor system (ESS) in minutes. This versatile method works for many types of thin metal and polymeric sheets and is compatible with many tattoo adhesives or medical tapes. The resultant ESS is highly multimaterial and multifunctional and may measure ECG, EMG, skin temperature, skin hydration, as well as respiratory rate. Also, a stretchable planar coil made of serpentine ribbons can be used as a wireless strain gauge and/or a near field communication (NFC) antenna. Other embodiments are described herein.
FILED	Wednesday, November 27, 2019
APPL NO	16/698825
ART UNIT	3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/25 (20210101) Original (OR) Class A61B 5/085 (20130101) A61B 5/296 (20210101) A61B 5/0537 (20130101) A61B 5/6833 (20130101) A61B 2562/02 (20130101) A61B 2562/06 (20130101) A61B 2562/12 (20130101) A61B 2562/125 (20130101) A61B 2562/0261 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 35/02 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2067/003 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/753 (20130101)
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11344635 — Compounds for use as iron (III) MRI contrast agents containing anionic pendents and ancillary groups

US 11344635	Morrow et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	The Research Foundation for The State University of New York (Buffalo, New York)
ASSIGNEE(S)	The Research Foundation for the State University of New York (Amherst, New York)
INVENTOR(S)	Janet R. Morrow (Williamsville, New York); Zuiru Lin (Williamsville, New York); Didar Asik (Tonawanda, New York); Eric M. Snyder (Tonawanda, New York); Elizabeth A. Kras (Amherst, New York)
ABSTRACT	Macrocyclic complexes and macrocyclic compounds. The macrocyclic complexes or macrocyclic compounds have a TACN moiety with one or more amine group(s) or a O- or S-substituted TACN moiety. The macrocyclic complexes have a high-spin Fe(III) atom coordinated to the TACN moiety. The macrocyclic complexes can be used in imaging methods.
FILED	Monday, November 18, 2019
APPL NO	16/973349
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 49/106 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/6515 (20130101) C07F 15/025 (20130101)
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11345595 — System and methods for fabricating boron nitride nanostructures

US 11345595	Fathalizadeh et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Aidin Fathalizadeh (Berkeley, California); Thang Pham (Berkeley, California); William Mickelson (Albany, California); Alexander Zettl (Kensington, California)
ABSTRACT	This disclosure provides systems, methods, and apparatus related to boron nitride nanomaterials. In one aspect, a method includes generating a directed flow of plasma. A boron-containing species is introduced to the directed flow of the plasma. Boron nitride nanostructures are formed in a chamber. In another aspect, a method includes generating a directed flow of plasma using nitrogen gas. A boron-containing species is introduced to the directed flow of the plasma. The boron-containing species can consist of boron powder, boron nitride powder, and/or boron oxide powder. Boron nitride nanostructures are formed in a chamber, with a pressure in the chamber being about 3 atmospheres or greater.
FILED	Wednesday, June 24, 2015
APPL NO	15/321177
ART UNIT	1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/08 (20130101) B01J 2219/0879 (20130101) B01J 2219/0894 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 21/064 (20130101) C01B 21/0641 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/82 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101) C01P 2004/13 (20130101) C01P 2004/24 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/583 (20130101) C04B 35/622 (20130101) C04B 2235/95 (20130101) C04B 2235/767 (20130101) C04B 2235/5276 (20130101) C04B 2235/5284 (20130101) C04B 2235/5454 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/762 (20130101) Y10S 977/896 (20130101)
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11345634 — Method of lightweight aggregates production from waste-coal combustion ash

US 11345634	Balapour et al.
FUNDED BY	National Science Foundation (NSF) Directorate of Technology, Innovation and Partnerships (TIP) Translational Impacts (TI)
APPLICANT(S)	Drexel University (Philadelphia, Pennsylvania)
ASSIGNEE(S)	Drexel University (Philadelphia, Pennsylvania)
INVENTOR(S)	Mohammad Balapour (Phladelphia, Pennsylvania); Yaghoob Farnam (Philadelphia, Pennsylvania); Yick Grace Hsuan (Ardmore, Pennsylvania)
ABSTRACT	Manufacturing lightweight aggregate (LWA) by a sintering technique requires a delicate balance among three conditions: forming sufficient amount of molten liquid phase during sintering; reaching an appropriate viscosity for solid-liquid suspension; and emitting sufficient amount of gas that can be entrapped by the liquid phase to form pores. LWAs were made from low-calcium and high-calcium Waste Coal Combustion Ash (W-CCA) including fly ash and bottom ash. A mass fraction of at least 40% liquid phase for fly ash and 50% for bottom ash is required for a successful entrapment of emitted gaseous phases during sintering. Larger pores were observed in the microstructure of LWA samples made using high-calcium W-CCA in comparison to low-calcium W-CCA. This result was mainly attributed to the high-calcium samples forming liquid phases with lower viscosity values and emitting higher amounts of gaseous phase during sintering than did the low-calcium samples. The gaseous phase was generated by hematite reduction and anhydrite decomposition.
FILED	Thursday, September 09, 2021
APPL NO	17/469945
ART UNIT	1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 18/027 (20130101) Original (OR) Class
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11345725 — Bis-thioether stapled peptides as inhibitors of PRC2 function

US 11345725	Gerona-Navarro et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF)
APPLICANT(S)	Research Foundation of the City University of New York (New York, New York)
ASSIGNEE(S)	Research Foundation of the City University of New York (New York, New York)
INVENTOR(S)	Guillermo Gerona-Navarro (New York, New York); Gan Zhang (Brooklyn, New York); Flavia Barragan (Berlin, Germany)
ABSTRACT	This disclosure describes three novel bisthioether stapled peptides as allosteric inhibitors of Polycomb Repressive Complex 2 (PRC2) catalytic function with demonstrated cell permeability, potent activity in physiological conditions, and strong antiproliferative effects on cancer cells. These inhibitors target, for the first time, two protein interfaces in PRC2 that are crucial for its proper assembling and thus for its histone methyltransferase activity.
FILED	Wednesday, September 16, 2020
APPL NO	17/022900
ART UNIT	1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Peptides C07K 7/08 (20130101) Original (OR) Class
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11345917 — Oligonucleotide compounds for treatment of preeclampsia and other angiogenic disorders

US 11345917	Khvorova et al.
FUNDED BY	National Science Foundation (NSF) Directorate of Geosciences (GEO) Office of Polar Programs (OPP)
APPLICANT(S)	UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts); BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (Boston, Massachusetts)
ASSIGNEE(S)	UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts); BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (Boston, Massachusetts)
INVENTOR(S)	Anastasia Khvorova (Westborough, Massachusetts); Melissa Moore (Chestnut Hill, Massachusetts); Anton A. Turanov (Boston, Massachusetts); Ananth Karumanchi (Chestnut Hill, Massachusetts)
ABSTRACT	This disclosure relates to novel targets for angiogenic disorders. Novel oligonucleotides are also provided. Methods of using the novel oligonucleotides for the treatment of angiogenic disorders (e.g., preeclampsia) are also provided.
FILED	Wednesday, November 06, 2019
APPL NO	16/675369
ART UNIT	1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) C12N 15/1138 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/50 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/322 (20130101) C12N 2310/344 (20130101) C12N 2310/346 (20130101) C12N 2310/351 (20130101)
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11345953 — Development of a highly sensitive quantification system for assessing DNA degradation and quality in forensic samples

US 11345953	Sinha
FUNDED BY	National Science Foundation (NSF) Directorate of Technology, Innovation and Partnerships (TIP) Translational Impacts (TI) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Life Genetics Lab, LLC (New Orleans, Louisiana)
ASSIGNEE(S)
INVENTOR(S)	Sudhir Sinha (New Orleans, Louisiana)
ABSTRACT	A process of quantifying the extent of degradation present in a human DNA sample is described. The process makes use of a real time PCR system to separately quantitate within a sample a first retrotransposon interspersed element and a relatively longer second retrotransposon interspersed element, where the longer element is expected to be disrupted at a faster pace than is the shorter element as the sample degrades. In one embodiment, the process makes use of the appearance of the relatively young (on an evolutionary scale) Alu Yb-lineage subfamily sequences appearing in every human genome and their virtual absence in non-human samples. In a preferred embodiment, the process quantifies longer 290 bp sequences of “SVA” elements and shorter 80 bp sequences of Alu Yb8-lineage. Newly designed primers and TaqMan probes that are useful in the process are presented. A related process additionally quantifies male specific human DNA.
FILED	Tuesday, March 13, 2018
APPL NO	15/920392
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6851 (20130101) Original (OR) Class C12Q 1/6876 (20130101) C12Q 2600/16 (20130101) C12Q 2600/166 (20130101)
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11346087 — Nanopatterned surfaces and methods for accelerated freezing and liquid recovery

US 11346087	Betz et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	Kansas State University Research Foundation (Manhattan, Kansas)
ASSIGNEE(S)	Kansas State University Research Foundation (Manhattan, Kansas)
INVENTOR(S)	Amy Betz (Manhattan, Kansas); Melanie Derby (Manhattan, Kansas)
ABSTRACT	Inventive surfaces, and methods of using the same, are provided that exhibit improved water collection and frost formation properties over prior art surfaces. The inventive surfaces have a plurality of nanosized recessed areas formed therein. The geometries and patterns of the recessed areas are particularly designed to discourage water droplet coalescence on the surfaces. Due to these designs, the surfaces are capable of forming and maintaining smaller, as well as asymmetrical, droplets on the surfaces. As a result, a greater surface area of the inventive surfaces can be covered by water droplets, thereby increasing water recovery. In addition, the smaller, asymmetrical droplets lead to desirable frost layer characteristics under non-cryogenic freezing conditions.
FILED	Friday, May 12, 2017
APPL NO	16/301236
ART UNIT	3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Installations or Methods for Obtaining, Collecting, or Distributing Water E03B 3/28 (20130101) Original (OR) Class Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 39/02 (20130101) Producing, Working or Handling Ice F25C 1/00 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 13/187 (20130101)
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11346103 — Systems and methods for a power-generating thermogalvanic brick

US 11346103	Phelan et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Tempe, Arizona); KINGS COLLEGE LONDON (London, United Kingdom); UNIVERSITY OF NEW SOUTH WALES (Sydney, Australia)
ASSIGNEE(S)	Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona); Kings College London (London, United Kingdom); Newsouth Innovations PTY Limited (Sydney, Australia)
INVENTOR(S)	Patrick Phelan (Tempe, Arizona); Leigh Aldous (London, United Kingdom); Robert Taylor (Sydney, Australia); Benjamin Obeng (Tempe, Arizona)
ABSTRACT	Various embodiments of systems and methods for a thermogalvanic brick are disclosed.
FILED	Friday, October 18, 2019
APPL NO	17/286311
ART UNIT	1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Structural Elements; Building Materials E04C 1/39 (20130101) Original (OR) Class Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/21 (20130101) H01G 9/2004 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/32 (20130101)
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11346619 — Manufacturable metal-graphene interface for highly efficient and durable condensers

US 11346619	Li et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina)
ASSIGNEE(S)	University of South Carolina (Columbia, South Carolina)
INVENTOR(S)	Chen Li (Chapin, South Carolina); Wei Chang (Columbia, South Carolina); Benli Peng (Columbia, South Carolina)
ABSTRACT	The present disclosure relates to efficient condensing operations and apparatuses. Methods of fabricating condensers and specifically condenser surfaces are also disclosed. A condensing apparatus can include a condenser surface having a substrate and one or more layers of graphene. The substrate can be formed of nickel and a nickel-graphene surface composite layer can be formed. The substrate-graphene composite can be highly durable, hydrophobic, and resistant to fouling. Dropwise condensation can be induced.
FILED	Wednesday, December 12, 2018
APPL NO	16/217100
ART UNIT	3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/26 (20130101) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 2339/04 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 21/02 (20130101) Original (OR) Class F28F 21/089 (20130101) F28F 2245/04 (20130101)
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11346829 — Methods and devices for detection of trimethylamine (TMA) and trimethylamine oxide (TMAO)

US 11346829	Suslick et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S)	Kenneth S. Suslick (Champaign, Illinois); Zheng Li (Urbana, Illinois); Maria K. LaGasse (Lenexa, Kansas)
ABSTRACT	The present disclosure provides methods for detection and quantification of trimethylamine (TMA) or trimethylamine oxide (TMAO) comprising passing a sample over a sensor comprising a substrate having a plurality of chemically responsive dyes selected from the following classes of chemically responsive dyes: metal-containing dyes, pH indicators, or solvatochromic/vapochromic dyes. The disclosure also provides devices and sensors for the detection and quantification of TMA, and methods of diagnosing a subject having trimethylaminuria (TMAU).
FILED	Wednesday, May 17, 2017
APPL NO	15/598257
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/78 (20130101) G01N 21/80 (20130101) G01N 31/22 (20130101) G01N 31/221 (20130101) G01N 33/12 (20130101) Original (OR) Class G01N 33/487 (20130101) G01N 2201/0221 (20130101)
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11347000 — Micro-plate reader for ELISA testing

US 11347000	Ozcan et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Office of Emerging Frontiers and Multidisciplinary Activities (EFMA)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Aydogan Ozcan (Los Angeles, California); Brandon Berg (Chatsworth, California); Bingen Cortazar (Los Angeles, California); Derek Tseng (Buena Park, California); Steve Wei Feng (Danville, California); Haydar Ozkan (Los Angeles, California); Omai Garner (Culver City, California); Dino Di Carlo (Los Angeles, California)
ABSTRACT	A micro-plate reader for use with a portable electronic device having a camera includes an opto-mechanical attachment configured to attach/detach to the portable electronic device and includes an array of illumination sources. A slot in the opto-mechanical attachment is dimensioned to receive an optically transparent plate containing an array of wells. Optical fibers are located in the opto-mechanical attachment and transmit light from each well to a reduced size header having, wherein the fiber array in the header has a cross-sectional area that is ≤10× the cross-sectional area of the wells in the plate. A lens located in the opto-mechanical attachment transmits light from the header fibers to the camera. Software executed on the portable electronic device or other computer is used to process the images to generate qualitative clinical determinations and/or quantitative index values for the separate wells.
FILED	Friday, June 17, 2016
APPL NO	15/737743
ART UNIT	1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 2300/0829 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/253 (20130101) G01N 33/5304 (20130101) G01N 2035/00099 (20130101) G01N 2201/08 (20130101) G01N 2201/0221 (20130101) Optical Elements, Systems, or Apparatus G02B 6/06 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Pictorial Communication, e.g Television H04N 5/225 (20130101)
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11347036 — Stereoscopic displays with addressable focus cues

US 11347036	Hua et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS)
APPLICANT(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
ASSIGNEE(S)	THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
INVENTOR(S)	Hong Hua (Tucson, Arizona); Xinda Hu (Sunnyvale, California)
ABSTRACT	The present invention relates generally to stereoscopic displays, and more particularly, but not exclusively, to stereoscopic displays with addressable focus cues.
FILED	Thursday, February 27, 2020
APPL NO	16/803168
ART UNIT	2872 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 17/086 (20130101) Original (OR) Class G02B 27/0101 (20130101) G02B 27/106 (20130101) G02B 27/0172 (20130101) G02B 30/22 (20200101) G02B 2027/011 (20130101) G02B 2027/0132 (20130101) G02B 2027/0134 (20130101) Pictorial Communication, e.g Television H04N 13/339 (20180501) H04N 13/344 (20180501)
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11348228 — System, method, and computer-accessible medium for virtual pancreatography

US 11348228	Kaufman et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)	The Research Foundation for The State University of New York (Albany, New York)
ASSIGNEE(S)	The Research Foundation for the State University of New York (, None)
INVENTOR(S)	Arie Kaufman (Plainview, New York); Konstantin Dmitriev (Port Jefferson, New York)
ABSTRACT	A system, method, and computer-accessible medium for using medical imaging data to screen for a cystic lesion(s) can include, for example, receiving first imaging information for an organ(s) of a one patient(s), generating second imaging information by performing a segmentation operation on the first imaging information to identify a plurality of tissue types, including a tissue type(s) indicative of the cystic lesion(s), identifying the cystic lesion(s) in the second imaging information, and applying a first classifier and a second classifier to the cystic lesion(s) to classify the cystic lesion(s) into one or more of a plurality of cystic lesion types. The first classifier can be a Random Forest classifier and the second classifier can be a convolutional neural network classifier. The convolutional neural network can include at least 6 convolutional layers, where the at least 6 convolutional layers can include a max-pooling layer(s), a dropout layer(s), and fully-connected layer(s).
FILED	Tuesday, June 26, 2018
APPL NO	16/626662
ART UNIT	2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 3/0454 (20130101) G06N 20/20 (20190101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 2207/20081 (20130101) G06T 2207/30096 (20130101)
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11348458 — Adaptive traffic control

US 11348458	Savla et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS) U.S. State Government State of California California Department of Transportation (CALTRANS)
APPLICANT(S)	UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
ASSIGNEE(S)	UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
INVENTOR(S)	Ketan Savla (Los Angeles, California); Pouyan Hosseini (Los Angeles, California)
ABSTRACT	The disclosure presents methods and apparatus for adaptive control of one or more traffic signals. A method may include determining an offset value based on a function of a traffic flow performance metric. The method may further include determining a green time split value based on a distributed algorithm. The method may further include adaptive control of the one or more traffic signals based on the green time split value and the offset value.
FILED	Friday, June 08, 2018
APPL NO	16/615104
ART UNIT	2684 — Telemetry and Code Generation Vehicles and System Alarms
CURRENT CPC	Traffic Control Systems G08G 1/08 (20130101) G08G 1/082 (20130101) Original (OR) Class G08G 1/0116 (20130101) G08G 1/0133 (20130101) G08G 1/0145 (20130101)
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11348778 — Precursor and neutral loss scan in an ion trap

US 11348778	Cooks et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Robert Graham Cooks (West Lafayette, Indiana); Dalton Snyder (West Lafayette, Indiana); Christopher Pulliam (West Lafayette, Indiana)
ABSTRACT	The invention generally relates to systems and methods for precursor and neutral loss scan in an ion trap. In certain aspects, the invention provides a system that includes a mass spectrometer having an ion trap, and a central processing unit (CPU). The CPU includes storage coupled to the CPU for storing instructions that when executed by the CPU cause the system to excite a precursor ion and eject a product ion in the single ion trap.
FILED	Wednesday, November 02, 2016
APPL NO	15/772738
ART UNIT	2881 — Optics
CURRENT CPC	Electric Discharge Tubes or Discharge Lamps H01J 49/0081 (20130101) Original (OR) Class H01J 49/424 (20130101)
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11348786 — Rubbing-induced site-selective growth of device patterns

US 11348786	Liang et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S)	Xiaogan Liang (Ann Arbor, Michigan); Byunghoon Ryu (Ann Arbor, Michigan)
ABSTRACT	The superior electronic and mechanical properties of 2D-layered transition metal dichalcogenides and other 2D layered materials could be exploited to make a broad range of devices with attractive functionalities. However, the nanofabrication of such layered-material-based devices still needs resist-based lithography and plasma etching processes for patterning layered materials into functional device features. Such patterning processes lead to unavoidable contaminations, to which the transport characteristics of atomically-thin layered materials are very sensitive. More seriously, such lithography-introduced contaminants cannot be safely eliminated by conventional material wafer cleaning approaches. This disclosure introduces a rubbing-induced site-selective growth method capable of directly generating few-layer molybdenum disulfide device patterns without the need of any additional patterning processes. This method consists of two critical steps: (i) a damage-free mechanical rubbing process for generating microscale triboelectric charge patterns on a dielectric surface, and (ii) site-selective deposition of molybdenum disulfide or the like within rubbing-induced charge patterns.
FILED	Tuesday, November 26, 2019
APPL NO	16/696038
ART UNIT	2818 — Semiconductors/Memory
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02013 (20130101) H01L 21/02568 (20130101) Original (OR) Class H01L 21/28568 (20130101) H01L 29/78684 (20130101) Electric Machines Not Otherwise Provided for H02N 1/04 (20130101)
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11349011 — Method of making heteroepitaxial structures and device formed by the method

US 11349011	Brueck et al.
FUNDED BY	Department of Defense (DOD) Defense Threat Reduction Agency (DTRA) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	UNM RAINFOREST INNOVATIONS (Albuquerque, New Mexico)
ASSIGNEE(S)
INVENTOR(S)	Steven R. J. Brueck (Albuquerque, New Mexico); Stephen D. Hersee (Albuquerque, New Mexico); Seung-Chang Lee (Albuquerque, New Mexico); Daniel Feezell (Albuquerque, New Mexico)
ABSTRACT	A method for making a heteroepitaxial layer. The method comprises providing a semiconductor substrate. A seed area delineated with a selective growth mask is formed on the semiconductor substrate. The seed area comprises a first material and has a linear surface dimension of less than 100 nm. A heteroepitaxial layer is grown on the seed area, the heteroepitaxial layer comprising a second material that is different from the first material. Devices made by the method are also disclosed.
FILED	Tuesday, January 21, 2020
APPL NO	16/748361
ART UNIT	2897 — Semiconductors/Memory
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 40/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02107 (20130101) H01L 21/02381 (20130101) H01L 21/02532 (20130101) H01L 21/02538 (20130101) H01L 21/02639 (20130101) H01L 27/1211 (20130101) H01L 29/04 (20130101) H01L 29/16 (20130101) H01L 29/20 (20130101) H01L 29/045 (20130101) H01L 29/0665 (20130101) H01L 29/0673 (20130101) H01L 29/0676 (20130101) H01L 29/775 (20130101) H01L 29/785 (20130101) H01L 29/7783 (20130101) H01L 29/7827 (20130101) H01L 29/7851 (20130101) H01L 29/66462 (20130101) Original (OR) Class H01L 29/66469 (20130101) H01L 29/66666 (20130101) H01L 29/66795 (20130101)
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11349091 — Halide perovskite thin films and methods for production thereof

US 11349091	Yu et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida)
ASSIGNEE(S)	THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida)
INVENTOR(S)	Zhibin Yu (Tallahassee, Florida); Thomas Geske (Tallahassee, Florida)
ABSTRACT	Methods are provided for making halide perovskite thin films. The method may include forming a pattern of islands of a nucleation promoter material onto a substrate; applying onto the substrate and islands a solution which includes a halide perovskite or precursors thereof, to form a coated substrate; and drying the coated substrate to form a crystalline halide perovskite film. Halide perovskite thin films, which may be made by these methods, and LEDs including these films are also provided.
FILED	Friday, May 18, 2018
APPL NO	16/614587
ART UNIT	1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 21/006 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/34 (20130101) C01P 2002/72 (20130101) C01P 2004/03 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0003 (20130101) H01L 51/0096 (20130101) H01L 51/4206 (20130101) Original (OR) Class
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11349144 — Rechargeable multi-cell battery

US 11349144	Qiao et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS) Department of Transportation (USDOT) Federal Highway Administration (FHWA) National Highway Traffic Safety Administration (NHTSA)
APPLICANT(S)	NUtech Ventures (Lincoln, Nebraska)
ASSIGNEE(S)	NUtech Ventures (Lincoln, Nebraska)
INVENTOR(S)	Wei Qiao (Lincoln, Nebraska); Taesic Kim (Lincoln, Nebraska); Liyan Qu (Lincoln, Nebraska)
ABSTRACT	A method for power management of a multi-cell battery includes identifying a desired power value and voltage value, determining a battery voltage value and a battery current value for a battery, determining a number of battery banks from a plurality of battery banks to use for the battery, where each battery bank includes one or more battery cells (or battery modules), checking availability of each of the one or more battery cells (or battery modules), selecting one or more battery banks from the plurality of battery banks, where the selection of a battery bank is based on the availability of the battery cells (or battery modules) included in the battery pack, and a quantity of the selected battery banks is equal to the determined number of battery banks, and connecting the available battery cells (or battery modules) in the selected one or more battery banks to form the battery.
FILED	Monday, April 15, 2019
APPL NO	16/384239
ART UNIT	2836 — Electrical Circuits and Systems
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/04 (20130101) Original (OR) Class H01M 10/4207 (20130101) H01M 2010/4271 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0021 (20130101) H02J 7/0024 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/70 (20130101)
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11349480 — Circuits based on magnetoelectric transistor devices

US 11349480	Gaul et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST) Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	Board of Regents of the University of Nebraska (Lincoln, Nebraska)
ASSIGNEE(S)	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska); INTEL CORPORATION (Santa Clara, California)
INVENTOR(S)	Nishtha Sharma Gaul (Richardson, Texas); Andrew Marshall (Dallas, Texas); Peter A. Dowben (Crete, Nebraska); Dmitri E. Nikonov (Beaverton, Oregon)
ABSTRACT	Logic circuits constructed with magnetoelectric (ME) transistors are described herein. A ME logic gate device can include at least one conducting device, for example, at least one MOS transistor; and at least one ME transistor coupled to the at least one conducting device. The ME transistor can be a ME field effect transistor (ME-FET), which can be can be an anti-ferromagnetic spin-orbit read (AFSOR) device or a non-AFSOR device. The gates and logic circuits described herein can be included as standard cells in a design library. Cells of the cell library can include standard cells for a ME inverter device, a ME minority gate device, a ME majority gate device, a ME full adder, a ME XNOR device, a ME XOR device, or a combination thereof.
FILED	Tuesday, September 24, 2019
APPL NO	16/581691
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/42312 (20130101) Pulse Technique H03K 19/10 (20130101) H03K 19/16 (20130101) Original (OR) Class H03K 19/21 (20130101)
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11349774 — Methods, systems and computer readable media for diagnosing network function virtualization performance

US 11349774	Anwer et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	AT and T Intellectual Property I, L.P. (Atlanta, Georgia); President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	AT and T Intellectual Property 1, L.P. (Atlanta, Georgia); President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Muhammad Bilal Anwer (Branchburg, New Jersey); Aman Shaikh (Berkeley Heights, New Jersey); Junzhi Gong (Cambridge, Massachusetts); Minlan Yu (Cambridge, Massachusetts); Yuliang Li (Cambridge, Massachusetts)
ABSTRACT	Performance issues in a service function chain having a plurality of resources and a plurality of network functions each having a network function queue are diagnosed. Each network function queue is monitored and queueing information for input packets for each of the plurality of network functions is dumped to a data store. Each resource that is under contention is identified as well as which of the network functions is a contender for the resources. A diagnosing algorithm is used to diagnose performance problems and an impact graph for each victim packet is generated. A summary of results as a list of rules is then provided.
FILED	Friday, December 13, 2019
APPL NO	16/714117
ART UNIT	2471 — Multiplex and VoIP
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 43/062 (20130101) H04L 43/0876 (20130101) H04L 47/522 (20130101) H04L 47/746 (20130101) H04L 47/748 (20130101) H04L 47/762 (20130101) Original (OR) Class H04L 47/803 (20130101)
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11349948 — Distributing cached content in a network

US 11349948	Mahdian et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	Northeastern University (Boston, Massachusetts)
ASSIGNEE(S)	Northeastern University (Boston, Massachusetts)
INVENTOR(S)	Milad Mahdian (New York, New York); Armin Moharrer (Chestnut Hill, Massachusetts); Efstratios Ioannidis (Boston, Massachusetts); Edmund Meng Yeh (Newton, Massachusetts)
ABSTRACT	The invention relates to a computer-implemented method, a corresponding a computer program product and a corresponding apparatus for distributing cached content in a network, the computer-implemented method comprising: collecting statistics regarding requests made and paths taken by the requests from source nodes to server nodes via intermediate nodes, the source nodes, intermediate nodes, and server nodes interconnected by edges having queues with respective queue sizes associated therewith, the requests including indications of content items to be retrieved; storing the content items at the server nodes; caching, by the intermediate nodes, the content items up to a caching capacity; and performing caching decisions that determine which of the content items are to be cached at which of the intermediate nodes, based upon costs that are monotonic, non-decreasing functions of the sizes of the queues.
FILED	Tuesday, May 07, 2019
APPL NO	17/050152
ART UNIT	2457 — Computer Networks
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 67/10 (20130101) H04L 67/2852 (20130101) Original (OR) Class
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Department of Agriculture (USDA)

11344027 — Cereal crop pollen field conditioning method

US 11344027	Cope et al.
FUNDED BY	Small Business Administration (SBA) Small Business Innovation Research (SBIR) Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	Accelerated Ag Technologies, LLC (Ames, Iowa)
ASSIGNEE(S)	Accelerated Ag Technologies, LLC (Ames, Iowa)
INVENTOR(S)	Jason Cope (Ankeny, Iowa); George Singletary (Ankeny, Iowa); Todd Krone (Des Moines, Iowa); Sara Katherine Etter (Bondurant, Iowa)
ABSTRACT	Described are methods of field conditioning cereal crop pollen. A method of the present invention includes collecting fresh pollen and introducing the pollen to field conditioning conditions which regulate pollen moisture content. The field conditioning conditions may include a relative humidity ranging from about 50% to about 100%, a temperature ranging from about −10-10° C., and an air pressure ranging from about 15 kPa to about 150 kPa. The field conditioning conditions may further include a continuous, adjustable positive or negative air flow and/or and a flow of one or more continuously refreshed, selected gases. The field conditioning conditions may dehydrate the pollen to achieve a pollen moisture content of about 40% to about 58%, such as about 50% to about 57%.
FILED	Thursday, February 27, 2020
APPL NO	16/803565
ART UNIT	1662 — Plants
CURRENT CPC	Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 7/00 (20130101) New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 1/02 (20130101) Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 3/00 (20130101) Original (OR) Class
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11344055 — Compositions of food grade coatings to control pest infestations and methods of applications

US 11344055	Schilling et al.
FUNDED BY	Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	Mississippi State University (Starkville, Mississippi); Kansas State University Research Foundation (Manhattan, Kansas)
ASSIGNEE(S)	Mississippi State University (Starkville, Mississippi); Kansas State University Research Foundation (Manhattan, Kansas)
INVENTOR(S)	Mark Wes Schilling (Starkville, Mississippi); Yan Zhao (Sheboygan, Wisconsin); Yan Campbell (Starkville, Mississippi); Thomas W. Phillips (Manhattan, Kansas); Salehe Abbar (Manhattan, Kansas); Barbara Amoah (Manhattan, Kansas)
ABSTRACT	The invention consists of novel compositions of food-grade coatings comprising mixtures containing propylene glycol as at least one active ingredient and containing at least one inert food-grade acceptable carrier for controlling food pests and pest infestations and reproduction on and/or in food. The invention further provides novel food containers and methods of applying coating compositions, including those of the invention, to foods and to food containers used to store, age, and/or cure the foods.
FILED	Friday, November 11, 2016
APPL NO	15/775829
ART UNIT	1791 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Catching, Trapping or Scaring of Animals; Apparatus for the Destruction of Noxious Animals or Noxious Plants A01M 17/008 (20130101) Preserving, e.g by Canning, Meat, Fish, Eggs, Fruit, Vegetables, Edible Seeds; Chemical Ripening of Fruit or Vegetables; the Preserved, Ripened, or Canned Products A23B 4/10 (20130101) A23B 4/20 (20130101) A23B 5/06 (20130101) A23B 5/14 (20130101) Dairy Products, e.g Milk, Butter, Cheese; Milk or Cheese Substitutes; Making Thereof A23C 19/10 (20130101) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 3/3463 (20130101) A23L 3/3481 (20130101) Shaping or Working of Foodstuffs, Not Fully Covered by a Single Other Subclass A23P 20/10 (20160801) A23P 20/105 (20160801) Original (OR) Class Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) A23V 2200/10 (20130101) A23V 2250/5026 (20130101) A23V 2250/5036 (20130101) A23V 2250/5086 (20130101) Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 29/04 (20130101) B65D 65/42 (20130101) B65D 81/28 (20130101)
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11344612 — Virulent Aeromonas vaccines and methods

US 11344612	Lawrence et al.
FUNDED BY	Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	MISSISSIPPI STATE UNIVERSITY (Starkville, Mississippi)
ASSIGNEE(S)	Mississippi State University (Starkville, Mississippi)
INVENTOR(S)	Mark L. Lawrence (Starkville, Mississippi); Attila Karsi (Starkville, Mississippi); Hossam Abdelhamed (Starkville, Mississippi)
ABSTRACT	Aeromonas hydrophila is a reemerging pathogen of channel catfish (Ictalurus punctatus); recent outbreaks from 2009 to 2014 have caused the loss of more than 12 million pounds of market size catfish in Alabama and Mississippi. Genome sequencing revealed a clonal group of A. hydrophila isolates with unique genetic and phenotypic features that is highly pathogenic in channel catfish. Comparison of the genome sequence of a representative catfish isolate (ML09-119) from this virulent clonal group with lower virulence A. hydrophila isolates revealed four fimbrial proteins unique to strain ML09-119. In this work, we expressed and purified four A. hydrophila fimbrial proteins (FimA, Fim, MrfG, and FimOM) and assessed their ability to protect and stimulate protective immunity in channel catfish fingerlings against A. hydrophila ML09-119 infection for vaccine development. Our results showed catfish immunized with FimA, Fim, FimMrfG, and FimOM exhibited 59.83%, 95.41%, 85.72%, and 75.01% relative percent survival, respectively, after challenge with A. hydrophila strain ML09-119. Bacterial concentrations in liver, spleen, and anterior kidney were significantly (p<0.05) lower in vaccinated fish compared to the non-vaccinated sham groups at 48 h post-infection. However, only the Fim immunized group showed a significantly higher antibody titer in comparison to the non-vaccinated treatment group (p<0.05) at 21 days post-vaccination. Altogether, Fim and FimMrfG recombinant proteins have potential for vaccine development against virulent A. hydrophila infection. Genomic subtraction revealed three outer membrane proteins present in strain ML09-119 but not in the low virulence reference A. hydrophila strain; the major outer membrane protein OmpAI (OmpA1), TonB-dependent receptor (TonB-DR), and transferrin-binding protein A (TbpA). Here, the genes encoding OmpAI, tonB-DR, and tbpA were cloned from A. hydrophila ML09-119 and were expressed into Escherichia coli. The purified recombinant OmpA, TonB-DR, and TbpA proteins had estimated molecular weights of 37.26, 78.55, and 41.67 kDa, respectively. Catfish fingerlings vaccinated with OmpA1, TonB-DR, and TbpA emulsified with non-mineral oil adjuvant were protected against the subsequent A. hydrophila ML09-119 infection with 98.59%, 95.59%, and 47.89% relative percent survival (RPS), respectively. Furthermore, the mean liver, spleen, and anterior kidney bacterial loads were significantly lower in catfish vaccinated with the OmpA1 and TonB-DR than the non-vaccinated control group. ELISA demonstrated that catfish immunized with OmpA1, TonB-DR, and TbpA produce significant antibody response by 21 days post-immunization. Therefore, data generated during the study suggest that OmpAI and TonB-DR proteins could be used as potential candidates for vaccine development against A. hydrophila epidemic strain infection. However, TbpA protein failed to provide such strong protection. Recombinant ATPase from A. hydrophila also showed promise as a vaccine antigen. A live attenuated vaccine was prepared that combined the advantages of a live attenuated vaccine (ESC-NDKL1 (ΔgcvPΔsdhCΔfrdA) mutant of Edwardsiella ictaluri) against enteric septicemia of catfish (ESC) and three immunogenic recombinant proteins (Fim, FimMrfg, and ATPase) against A. hydrophila infection. Our results showed channel catfish fingerlings immersion-vaccinated with ESC-NDKL1::pETfim, ESC-NDKL1::pETmrfG, and ESC-NDKL1::pETATPase exhibited 100%, 91.67%, and 100% percent survival after challenge with the A. hydrophila ML09-119, which was significantly less than non-vaccinated group (88.89% mortality). In a second study, Catfish immunized with NDKL1::pETfim, ESC-NDKL1::pETmrfG, ESC-NDKL1::pETATPase had significantly (p<0.05) lower mortalities than sham-vaccinated group.
FILED	Friday, December 08, 2017
APPL NO	16/467166
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/025 (20130101) A61K 39/0208 (20130101) Original (OR) Class A61K 2039/70 (20130101) A61K 2039/522 (20130101) A61K 2039/523 (20130101) A61K 2039/552 (20130101) A61K 2039/55566 (20130101)
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Department of Transportation (USDOT)

11345245 — Overhead charging systems for electric vehicles

US 11345245	Hill et al.
FUNDED BY	Department of Transportation (USDOT) Federal Transit Administration (FTA)
APPLICANT(S)	Proterra Operating Company, Inc. (Burlingame, California)
ASSIGNEE(S)	Proterra Operating Company, Inc. (Burlingame, California)
INVENTOR(S)	Dale Hill (New Braunfels, Texas); Michael Walker (Dale City, California); Joshua Goldman (San Diego, California); John Horth (Evergreen, Colorado)
ABSTRACT	This disclosure provides systems and methods for charging a vehicle. A vehicle and charging station can be designed such that an electric or hybrid vehicle can operate in a fashion similar to a conventional vehicle by being opportunity charged throughout a known route.
FILED	Tuesday, October 02, 2018
APPL NO	16/149919
ART UNIT	2859 — Printing/Measuring and Testing
CURRENT CPC	Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 5/005 (20130101) B60L 5/42 (20130101) B60L 53/11 (20190201) B60L 53/14 (20190201) Original (OR) Class B60L 53/30 (20190201) B60L 53/31 (20190201) B60L 53/32 (20190201) B60L 53/35 (20190201) B60L 2200/18 (20130101) B60L 2200/26 (20130101) Power Supply Lines, and Devices Along Rails, for Electrically- Propelled Vehicles B60M 7/003 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/007 (20130101) H02J 7/0021 (20130101) H02J 7/0042 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/70 (20130101) Y02T 10/7072 (20130101) Y02T 90/12 (20130101) Y02T 90/14 (20130101)
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11346678 — System and method for estimating and predicting vehicle trip energy consumption

US 11346678	Trancik et al.
FUNDED BY	Department of Transportation (USDOT)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Jessika E. Trancik (Somerville, Massachusetts); Zachary A. Needell (Cambridge, Massachusetts); James McNerney (Somerville, Massachusetts)
ABSTRACT	A system for estimating or predicting energy consumption for a trip of a personal vehicle includes a user facing portion and a back-end portion. The user facing portion includes a display and a user interface hosting a real-time application configured to receive travel information and present a received energy distribution via the display. The back-end portion includes a back-end database and an energy processor configured to access the back-end database. The energy processor includes a demand model module configured to produce a set of possible velocity histories and a set of possible ambient temperatures. A vehicle model module is configured to receive the velocity histories and ambient temperatures to provide the energy distribution or a probabilistic prediction of future energy consumption to the user facing portion.
FILED	Tuesday, August 15, 2017
APPL NO	15/677256
ART UNIT	3668 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles B60K 35/00 (20130101) B60K 37/02 (20130101) B60K 2370/29 (20190501) B60K 2370/155 (20190501) B60K 2370/174 (20190501) B60K 2370/334 (20190501) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/3469 (20130101) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/14 (20130101) G01S 19/42 (20130101) Electric Digital Data Processing G06F 16/90 (20190101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/04 (20130101) G06Q 10/06 (20130101) G06Q 10/0631 (20130101) G06Q 10/06315 (20130101) G06Q 50/30 (20130101)
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11349144 — Rechargeable multi-cell battery

US 11349144	Qiao et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS) Department of Transportation (USDOT) Federal Highway Administration (FHWA) National Highway Traffic Safety Administration (NHTSA)
APPLICANT(S)	NUtech Ventures (Lincoln, Nebraska)
ASSIGNEE(S)	NUtech Ventures (Lincoln, Nebraska)
INVENTOR(S)	Wei Qiao (Lincoln, Nebraska); Taesic Kim (Lincoln, Nebraska); Liyan Qu (Lincoln, Nebraska)
ABSTRACT	A method for power management of a multi-cell battery includes identifying a desired power value and voltage value, determining a battery voltage value and a battery current value for a battery, determining a number of battery banks from a plurality of battery banks to use for the battery, where each battery bank includes one or more battery cells (or battery modules), checking availability of each of the one or more battery cells (or battery modules), selecting one or more battery banks from the plurality of battery banks, where the selection of a battery bank is based on the availability of the battery cells (or battery modules) included in the battery pack, and a quantity of the selected battery banks is equal to the determined number of battery banks, and connecting the available battery cells (or battery modules) in the selected one or more battery banks to form the battery.
FILED	Monday, April 15, 2019
APPL NO	16/384239
ART UNIT	2836 — Electrical Circuits and Systems
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/04 (20130101) Original (OR) Class H01M 10/4207 (20130101) H01M 2010/4271 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0021 (20130101) H02J 7/0024 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/70 (20130101)
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National Aeronautics and Space Administration (NASA)

11346330 — Additively manufactured components for electric propulsion thrusters

US 11346330	Xu et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	Board of Trustees of the University of Alabama, for and on behalf of the University of Alabama in Huntsville (Huntsville, Alabama)
ASSIGNEE(S)	Board of Trustees of the University of Alabama, for and on behalf of the University of Alabama in Huntsville (Huntsville, Alabama)
INVENTOR(S)	Kunning Gabriel Xu (Brownsboro, Alabama); Ethan Paul Hopping (Clinton, Tennessee)
ABSTRACT	A Hall effect thruster is provided having one or more components fabricated using additive manufacturing techniques. Additive manufacturing can be used to fabricate the propellant distributor and the discharge channel of the thruster. The propellant distributor can be separated from the anode of the thruster and can form the base of the discharge channel. The discharge channel can be detachably connected to the propellant distributor using one of a threaded connection or a snap-fit connection. The discharge channel can have an annular shape and electromagnets and magnetic poles can be placed in the surrounding areas of the discharge channel.
FILED	Friday, August 24, 2018
APPL NO	16/111840
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Producing a Reactive Propulsive Thrust, Not Otherwise Provided for F03H 1/0075 (20130101) Original (OR) Class Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G F05B 2230/20 (20130101) F05B 2280/2004 (20130101) F05B 2280/4003 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/54 (20130101)
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11346718 — Spectral imaging system

US 11346718	Thorpe et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) Jet Propulsion Laboratory (JPL) Federally Funded Research and Development Center (FFRDC) Operated by California Institute of Technology (CALTECH) at Pasadena, CA
APPLICANT(S)	California Institute of Technology (Pasadena, California)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California)
INVENTOR(S)	Andrew K. Thorpe (Pasadena, California); Robert O. Green (Palmdale, California); Pantazis Mouroulis (Glendora, California); David R. Thompson (Pasadena, California); Andrew D. Aubrey (Austin, Texas); Christian Frankenberg (Pasadena, California)
ABSTRACT	A freeform imaging system with a spectrometer and telescope components optically connected and optimized to increase the spectral and spatial resolution capabilities. Many embodiments of the system are capable of producing a spectral resolution of approximately 1 nm and a spatial resolution less than 30 m such that the imaging system can be used to accurately capture and measure point source plumes of various atmospheric gases including CH₄, CO₂, CO, N₂O, and H₂O.
FILED	Monday, October 21, 2019
APPL NO	16/658500
ART UNIT	2886 — Optics
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/0205 (20130101) G01J 3/2823 (20130101) Original (OR) Class G01J 2003/2866 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/31 (20130101) G01N 21/274 (20130101)
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11348778 — Precursor and neutral loss scan in an ion trap

US 11348778	Cooks et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Robert Graham Cooks (West Lafayette, Indiana); Dalton Snyder (West Lafayette, Indiana); Christopher Pulliam (West Lafayette, Indiana)
ABSTRACT	The invention generally relates to systems and methods for precursor and neutral loss scan in an ion trap. In certain aspects, the invention provides a system that includes a mass spectrometer having an ion trap, and a central processing unit (CPU). The CPU includes storage coupled to the CPU for storing instructions that when executed by the CPU cause the system to excite a precursor ion and eject a product ion in the single ion trap.
FILED	Wednesday, November 02, 2016
APPL NO	15/772738
ART UNIT	2881 — Optics
CURRENT CPC	Electric Discharge Tubes or Discharge Lamps H01J 49/0081 (20130101) Original (OR) Class H01J 49/424 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Small Business Administration (SBA)

11344027 — Cereal crop pollen field conditioning method

US 11344027	Cope et al.
FUNDED BY	Small Business Administration (SBA) Small Business Innovation Research (SBIR) Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	Accelerated Ag Technologies, LLC (Ames, Iowa)
ASSIGNEE(S)	Accelerated Ag Technologies, LLC (Ames, Iowa)
INVENTOR(S)	Jason Cope (Ankeny, Iowa); George Singletary (Ankeny, Iowa); Todd Krone (Des Moines, Iowa); Sara Katherine Etter (Bondurant, Iowa)
ABSTRACT	Described are methods of field conditioning cereal crop pollen. A method of the present invention includes collecting fresh pollen and introducing the pollen to field conditioning conditions which regulate pollen moisture content. The field conditioning conditions may include a relative humidity ranging from about 50% to about 100%, a temperature ranging from about −10-10° C., and an air pressure ranging from about 15 kPa to about 150 kPa. The field conditioning conditions may further include a continuous, adjustable positive or negative air flow and/or and a flow of one or more continuously refreshed, selected gases. The field conditioning conditions may dehydrate the pollen to achieve a pollen moisture content of about 40% to about 58%, such as about 50% to about 57%.
FILED	Thursday, February 27, 2020
APPL NO	16/803565
ART UNIT	1662 — Plants
CURRENT CPC	Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 7/00 (20130101) New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 1/02 (20130101) Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 3/00 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

11345953 — Development of a highly sensitive quantification system for assessing DNA degradation and quality in forensic samples

US 11345953	Sinha
FUNDED BY	National Science Foundation (NSF) Directorate of Technology, Innovation and Partnerships (TIP) Translational Impacts (TI) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Life Genetics Lab, LLC (New Orleans, Louisiana)
ASSIGNEE(S)
INVENTOR(S)	Sudhir Sinha (New Orleans, Louisiana)
ABSTRACT	A process of quantifying the extent of degradation present in a human DNA sample is described. The process makes use of a real time PCR system to separately quantitate within a sample a first retrotransposon interspersed element and a relatively longer second retrotransposon interspersed element, where the longer element is expected to be disrupted at a faster pace than is the shorter element as the sample degrades. In one embodiment, the process makes use of the appearance of the relatively young (on an evolutionary scale) Alu Yb-lineage subfamily sequences appearing in every human genome and their virtual absence in non-human samples. In a preferred embodiment, the process quantifies longer 290 bp sequences of “SVA” elements and shorter 80 bp sequences of Alu Yb8-lineage. Newly designed primers and TaqMan probes that are useful in the process are presented. A related process additionally quantifies male specific human DNA.
FILED	Tuesday, March 13, 2018
APPL NO	15/920392
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6851 (20130101) Original (OR) Class C12Q 1/6876 (20130101) C12Q 2600/16 (20130101) C12Q 2600/166 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

11349279 — Optically cooled platform for thermal management applications

US 11349279	Osinski et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	STC.UNM (Albuquerque, New Mexico)
ASSIGNEE(S)	UNM Rainforest Innovations (Albuquerque, New Mexico)
INVENTOR(S)	Marek Osinski (Albuquerque, New Mexico); Alexander Neumann (Albuquerque, New Mexico); Gennady A. Smolyakov (Albuquerque, New Mexico)
ABSTRACT	A semiconductor device comprising a waveguide having a core, said core having inserted therein one or more layers of nanoemitters.
FILED	Tuesday, January 28, 2020
APPL NO	16/775200
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0408 (20130101) H01S 5/026 (20130101) H01S 5/341 (20130101) H01S 5/347 (20130101) H01S 5/02469 (20130101) Original (OR) Class H01S 5/3412 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

United States Postal Service (USPS)

11344918 — System and method of sorting and sequencing items

US 11344918	Bombaugh
FUNDED BY	United States Postal Service (USPS)
APPLICANT(S)	United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S)	United States Postal Service (Washington, District of Columbia)
INVENTOR(S)	Scott R. Bombaugh (Burke, Virginia)
ABSTRACT	Embodiments of a system and method for sorting and sequencing articles in a processing facility are disclosed. Delivery endpoints are divided and grouped into stop groups. A first sorter sorts items according to stop group and outputs the items to trays. The output trays from the first sorter are loaded to a second sorter in stop group order. The second sorter sorts items for each stop group into separate lanes. Each lane can then be sorted into output bins in delivery sequence order.
FILED	Tuesday, May 12, 2020
APPL NO	16/872895
ART UNIT	3653 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 1/025 (20130101) B07C 3/02 (20130101) Original (OR) Class B07C 3/08 (20130101) B07C 3/14 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

11348056 — Digital stamps

US 11348056	Jones et al.
FUNDED BY	United States Postal Service (USPS)
APPLICANT(S)	United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S)	UNITED STATES POSTAL SERVICE (Washington, District of Columbia)
INVENTOR(S)	Anthony Cramer Jones (Brooklyn, New York); Dominik Heinrich (New York, New York); Caspar Serge Ouvaroff (New York, New York)
ABSTRACT	The present disclosure provides methods and systems for the collection and delivery of physical items. Implementations consistent with the present disclosure provide a method including receiving, by a user interface device, a request from a user to deliver an item to a destination using a digital stamp, wherein the item includes destination information. The method also includes receiving, by the user interface device, a destination address from the user. The method also includes providing, by the user interface device, the delivery fee for the item. The method also includes generating the digital stamp using the destination address received from the user, the delivery fee for the item, and user account information. The method also includes collecting the item, wherein the item lacks any physical indicia that the delivery fee for the item has been paid or will be paid.
FILED	Thursday, December 21, 2017
APPL NO	15/850914
ART UNIT	3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC	Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0832 (20130101) Original (OR) Class G06Q 20/3223 (20130101) G06Q 50/32 (20130101) Ticket-issuing Apparatus; Fare-registering Apparatus; Franking Apparatus G07B 17/00508 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

11349956 — Interceptor hub for service-consuming applications

US 11349956	Cole
FUNDED BY	United States Postal Service (USPS)
APPLICANT(S)	UNITED STATES POSTAL SERVICE (Washington, District of Columbia)
ASSIGNEE(S)	UNITED STATES POSTAL SERVICE (Washington, District of Columbia)
INVENTOR(S)	Craig Alan Cole (Farmington, Minnesota)
ABSTRACT	A method, a computing device, and a computer program product are provided. An interceptor hub application receives, via a network, a request for multiple services from a first service-consuming application. The request is in a format for an interceptor interface. The interceptor hub application converts at least some information in the received request to a format of a corresponding interface of at least one of the requested services. The interceptor hub application sends a respective request to each of the requested services. The each respective request includes a corresponding portion of the information in the format of the corresponding service-oriented interface. A respective service response from the each of the respective services is received by the interceptor hub application, which provides each of the respective responses in a combined service response to the first service-consuming application in a format expected by the first service-consuming application.
FILED	Monday, July 12, 2021
APPL NO	17/372684
ART UNIT	2441 — Computer Networks
CURRENT CPC	Electric Digital Data Processing G06F 9/547 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/16 (20130101) H04L 67/40 (20130101) H04L 67/327 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

Department of Commerce (DOC)

11346690 — Device with water-activated, automatic disconnect

US 11346690	Cardenas et al.
FUNDED BY	Department of Commerce (DOC) National Oceanic and Atmospheric Administration (NOAA)
APPLICANT(S)	Boston Engineering Corporation (Waltham, Massachusetts)
ASSIGNEE(S)	Boston Engineering Corporation (Waltham, Massachusetts)
INVENTOR(S)	Robert Lee Cardenas (Framingham, Massachusetts); Michael Conry (Beverly, Massachusetts); Michael Rufo (Hanover, Massachusetts)
ABSTRACT	A technique for managing an attachment between first and second portions of a device. The technique includes a retaining component having a first state in which the retaining component maintains the attachment between the first and second portions by virtue of a rigid characteristic and a second state in which the retaining component loses the rigid characteristic and no longer maintains the attachment. The retaining component transitions from the first state to the second state upon exposure to liquid water.
FILED	Tuesday, April 21, 2020
APPL NO	16/854533
ART UNIT	3617 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Ships or Other Waterborne Vessels; Equipment for Shipping B63B 22/003 (20130101) B63B 22/08 (20130101) B63B 2022/006 (20130101) Launching, Hauling-out, or Dry-docking of Vessels; Life-saving in Water; Equipment for Dwelling or Working Under Water; Means for Salvaging or Searching for Underwater Objects B63C 7/26 (20130101) Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 11/245 (20130101) Original (OR) Class G01D 21/02 (20130101) Electric Digital Data Processing G06F 8/61 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

11349480 — Circuits based on magnetoelectric transistor devices

US 11349480	Gaul et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST) Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	Board of Regents of the University of Nebraska (Lincoln, Nebraska)
ASSIGNEE(S)	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska); INTEL CORPORATION (Santa Clara, California)
INVENTOR(S)	Nishtha Sharma Gaul (Richardson, Texas); Andrew Marshall (Dallas, Texas); Peter A. Dowben (Crete, Nebraska); Dmitri E. Nikonov (Beaverton, Oregon)
ABSTRACT	Logic circuits constructed with magnetoelectric (ME) transistors are described herein. A ME logic gate device can include at least one conducting device, for example, at least one MOS transistor; and at least one ME transistor coupled to the at least one conducting device. The ME transistor can be a ME field effect transistor (ME-FET), which can be can be an anti-ferromagnetic spin-orbit read (AFSOR) device or a non-AFSOR device. The gates and logic circuits described herein can be included as standard cells in a design library. Cells of the cell library can include standard cells for a ME inverter device, a ME minority gate device, a ME majority gate device, a ME full adder, a ME XNOR device, a ME XOR device, or a combination thereof.
FILED	Tuesday, September 24, 2019
APPL NO	16/581691
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/42312 (20130101) Pulse Technique H03K 19/10 (20130101) H03K 19/16 (20130101) Original (OR) Class H03K 19/21 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Department of Homeland Security (DHS)

11347887 — Value-based information flow tracking in software packages

US 11347887	Zonouz et al.
FUNDED BY	Department of Homeland Security (DHS)
APPLICANT(S)	Rutgers, The State University of New Jersey (New Brunswick, New Jersey); The Regents of the University of California (Los Angeles, California)
ASSIGNEE(S)	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Saman Aliari Zonouz (Jersey City, New Jersey); Gabriel Salles-Loustau (Highland Park, New Jersey); Mani Srivastava (Sherman Oaks, California); Moustafa Alzantot (Los Angeles, California)
ABSTRACT	A computer-implemented method, computer system, and computer program product are directed to improving computer security of a device using value based information flow tracking. Embodiments automatically capture raw data values from a data source of the device and store in memory the captured raw data values in a collection of sensitive data. Embodiments determine whether computed values of functions of a data flow are included in the collection of sensitive data. Based upon the determining, embodiments prevent values of the collection of sensitive data from being transmitted from a sink of the device. Embodiments may determine whether string representations of computed operand and return values of numerical or arithmetic operations of the functions of the data flow are included in the collection of sensitive data.
FILED	Tuesday, October 02, 2018
APPL NO	16/650369
ART UNIT	2438 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 21/52 (20130101) G06F 21/552 (20130101) G06F 21/6245 (20130101) Original (OR) Class G06F 2221/034 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

11348093 — System and method for merchant and personal transactions using mobile identification credential

US 11348093	Boyd et al.
FUNDED BY	Department of Homeland Security (DHS)
APPLICANT(S)	The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S)	The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
INVENTOR(S)	Daniel A. Boyd (Arlington, Virginia); Kelli L. Biegger (McLean, Virginia); Chang Ellison (Arlington, Virginia); Brandon P. Gutierrez (Burke, Virginia); Jason Lim (Alexandria, Virginia)
ABSTRACT	In an example involving a transaction conducted between a first party using a user mobile-identification-credential device (UMD) and a second party using a relying party system (RPS), RPS receives a request from UMD for transfer of an item, requests identification information of the first party from UMD, receives, based on consent of the first party, some or all user ID information associated with a mobile identification credential (MIC) which UMD received from an authorizing party system (APS), receives verification of the received user ID information, uses the verified user ID information to verify or not verify an identity of the first party, grants the request to transfer the item in exchange for payment or another item to be transferred from the first party to the second party when the identity of the first party is verified, and denies the request when the identity of the first party is not verified.
FILED	Thursday, October 21, 2021
APPL NO	17/507016
ART UNIT	2887 — Optics
CURRENT CPC	Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 20/326 (20200501) G06Q 20/347 (20130101) Original (OR) Class G06Q 20/3224 (20130101) G06Q 20/3226 (20130101) G06Q 20/3674 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Department of Justice (DOJ)

11345965 — Materials and methods for multiplex detection of body fluids

US 11345965	McCord et al.
FUNDED BY	Department of Justice (DOJ) Office of Justice Programs (OJP) National Institute of Justice (NIJ)
APPLICANT(S)	Bruce McCord (Miami, Florida); Quentin Gauthier (Miami, Florida); Sohee Cho (Miami, Florida)
ASSIGNEE(S)	THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S)	Bruce McCord (Miami, Florida); Quentin Gauthier (Miami, Florida); Sohee Cho (Miami, Florida)
ABSTRACT	The invention pertains to analyzing the levels of DNA methylation at specific genetic loci to detect specific body fluids, for example, vaginal secretions or vaginal epithelial cells, semen or sperms, saliva or buccal epithelial cells, or blood or blood cells. Particularly, the levels of methylation of DNA at the genetic loci corresponding to SEQ ID NOs: 1, 6, 11, and 16, more particularly, SEQ ID NOs: 25, 26, 27, and 28, are used to detect vaginal secretions or vaginal epithelial cells, semen or sperms, saliva or buccal epithelial cells, and blood or blood cells, respectively. The level of methylation at the specific loci can be determined by sequencing of the amplicons produced using specific primers designed to amplify the specific loci. Kits containing the primers and reagents for carrying out the methods disclosed herein are also provided.
FILED	Wednesday, November 25, 2020
APPL NO	17/104273
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6827 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/118 (20130101) C12Q 2600/154 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Department of Veterans Affairs (DVA)

11345894 — Cellular seeding and co-culture of a three dimensional fibroblast construct

US 11345894	Lancaster et al.
FUNDED BY	Department of Veterans Affairs (DVA)
APPLICANT(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
ASSIGNEE(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
INVENTOR(S)	Jordan Lancaster (Tucson, Arizona); Steve Goldman (Tucson, Arizona)
ABSTRACT	The present invention provides methods for cellular seeding onto three-dimensional fibroblast constructs, three-dimensional fibroblast constructs seeded with muscle cells, and uses therefore.
FILED	Monday, April 02, 2018
APPL NO	15/943322
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/33 (20130101) A61K 35/34 (20130101) A61K 35/44 (20130101) A61K 45/06 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/367 (20130101) A61L 27/3604 (20130101) A61L 27/3826 (20130101) A61L 2300/64 (20130101) A61L 2430/20 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) C12N 5/0657 (20130101) Original (OR) Class C12N 2502/28 (20130101) C12N 2502/1323 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Environmental Protection Agency (EPA)

11345617 — Microwave drying apparatus for the minimization of drinking water plant residuals

US 11345617	Lytle et al.
FUNDED BY	Environmental Protection Agency (EPA)
APPLICANT(S)	U.S. Environmental Protection Agency (Washington, District of Columbia)
ASSIGNEE(S)	U.S. ENVIRONMENTAL PROTECTION AGENCY (Washington, District of Columbia)
INVENTOR(S)	Darren A. Lytle (Liberty, Ohio); Mallikarjuna N. Nadagouda (Mason, Ohio)
ABSTRACT	A method and apparatus for treating residuals or waste streams from a plant, such as a drinking water treatment plant. The method includes the steps of obtaining plant residuals or waste streams from a water treatment plant and irradiating the plant residuals or waste streams using microwave radiation from a microwave source. The method also includes the step of drying the plant residuals or waste streams to a predetermined moisture, volume, or weight content reduction and disposing of the same.
FILED	Tuesday, February 27, 2018
APPL NO	15/906157
ART UNIT	3754 — Fluid Handling and Dispensing
CURRENT CPC	Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/302 (20130101) Original (OR) Class C02F 11/131 (20190101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 6/804 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

National Reconnaissance Office (NRO)

11346329 — Propulsion systems including an electrically actuated valve

US 11346329	Lozano et al.
FUNDED BY	Department of Defense (DOD) National Reconnaissance Office (NRO)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Paulo C. Lozano (Arlington, Massachusetts); Dakota Freeman (Cambridge, Massachusetts)
ABSTRACT	Propulsion systems, such as electrospray thrusters, may include an electrically actuated valve to permit a selective flow of propellant to a thruster. The valve may be located and arranged such that it physically separates a propellant, such as a source of ions, from a thruster of the propulsion system. In some embodiments, the application of a voltage potential to the valve may wet a plurality of through holes formed in the valve with the propellant such that the propellant flows through the valve to the thruster. After the valve has been opened, the propulsion system may be operated normally.
FILED	Thursday, May 30, 2019
APPL NO	16/427179
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Spraying Apparatus; Atomising Apparatus; Nozzles B05B 5/1608 (20130101) Producing a Reactive Propulsive Thrust, Not Otherwise Provided for F03H 1/0037 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

U.S. State Government

11348458 — Adaptive traffic control

US 11348458	Savla et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS) U.S. State Government State of California California Department of Transportation (CALTRANS)
APPLICANT(S)	UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
ASSIGNEE(S)	UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
INVENTOR(S)	Ketan Savla (Los Angeles, California); Pouyan Hosseini (Los Angeles, California)
ABSTRACT	The disclosure presents methods and apparatus for adaptive control of one or more traffic signals. A method may include determining an offset value based on a function of a traffic flow performance metric. The method may further include determining a green time split value based on a distributed algorithm. The method may further include adaptive control of the one or more traffic signals based on the green time split value and the offset value.
FILED	Friday, June 08, 2018
APPL NO	16/615104
ART UNIT	2684 — Telemetry and Code Generation Vehicles and System Alarms
CURRENT CPC	Traffic Control Systems G08G 1/08 (20130101) G08G 1/082 (20130101) Original (OR) Class G08G 1/0116 (20130101) G08G 1/0133 (20130101) G08G 1/0145 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Government Rights Acknowledged

11346252 — Multi-purpose anti-rotation lock pin

US 11346252	Giannakopoulos et al.
FUNDED BY
APPLICANT(S)	United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S)	RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S)	Konstantinos Panagiotis Giannakopoulos (Middletown, Connecticut); Thomas Carlsen (Greer, South Carolina)
ABSTRACT	A case assembly for a gas turbine engine includes a case extending circumferentially about an engine central longitudinal axis and two or more components installed in the case at different axial and/or radial locations. A retainer is installed at a circumferential end of the case, the retainer configured to circumferentially retain the two or more components at the case. A circumferential retainer of a case assembly of a gas turbine engine includes a retainer pin configured for installation in retaining feature of a circumferential end of a case, and one or more retainer arms extending from the retainer pin. The one or more retainer arms are configured to extend at least partially across two or more components installed in the case at different axial and/or radial locations to circumferentially retain the two or more components at the case.
FILED	Monday, July 01, 2019
APPL NO	16/458729
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/02 (20130101) F01D 11/005 (20130101) F01D 25/246 (20130101) Original (OR) Class F01D 25/265 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/55 (20130101) F05D 2260/30 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

11348310 — Building mask generation from 3D point set

US 11348310	Ely
FUNDED BY
APPLICANT(S)	Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S)	Raytheon Company (Waltham, Massachusetts)
INVENTOR(S)	Richard W. Ely (Lewisville, Texas)
ABSTRACT	Discussed herein are devices, systems, and methods for building mask generation. A method can include setting a respective pixel value of an image to a first specified value if the respective pixel corresponds, according to a three-dimensional (3D) point set, to an elevation greater than a specified Z threshold, otherwise setting the respective pixel value to a second, different specified value, grouping contiguous pixels set to the first specified value into one or more groups, determining a feature of each of the one or more groups, comparing the determined feature to a threshold and retaining the group if the feature is greater than a threshold, otherwise removing the group, and providing a building mask that includes pixels of the retained group set to a value and other pixels set to a different value.
FILED	Wednesday, November 13, 2019
APPL NO	16/683068
ART UNIT	2645 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC	Image Data Processing or Generation, in General G06T 7/45 (20170101) G06T 7/593 (20170101) G06T 17/05 (20130101) Original (OR) Class G06T 17/20 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

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The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

A61B 1/149 (20130101)
A61B 1/71 (20130101)
A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20220531.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital