FedInvent™ Patents
Patent Details for Tuesday, June 21, 2022
This page was updated on Saturday, June 25, 2022 at 05:43 PM GMT
Department of Health and Human Services (HHS)
| US 11363982 | Giuffrida et al. |
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| FUNDED BY |
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| APPLICANT(S) | Great Lakes NeuroTechnologies Inc. (Cleveland, Ohio) |
| ASSIGNEE(S) | Great Lakes NeuroTechnologies Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Joseph P. Giuffrida (Hinckley, Ohio); Dustin A. Heldman (Shaker Heights, Ohio) |
| ABSTRACT | A system and method for scoring movement disorder symptoms comprises a movement measurement data acquisition system and processing comprising kinematic feature extraction and an algorithm trained using Unified Parkinson's Disease Rating Scale (UPDRS) scores from skilled clinicians. The movement data acquisition system, or “movement measuring apparatus,” may comprise sensors such as accelerometers or gyroscopes or may utilize motion capture and/or machine vision technology or various other methods to measure tremor, bradykinesia, dyskinesia, or other movement disorders in a subject afflicted with Parkinson's disease, essential tremor or the like. The method outputs, and system displays, a score that uses the same scale as the UPDRS but has greater resolution and lower variability. In some embodiments, the system is used to diagnose and/or treat the patient by providing recommendations for treatment and/or by supplying treatment in the form of pharmaceutical drugs and/or electric stimulus as part of a closed-loop system. |
| FILED | Thursday, August 15, 2019 |
| APPL NO | 16/541347 |
| ART UNIT | 3626 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0022 (20130101) A61B 5/1101 (20130101) A61B 5/4082 (20130101) Original (OR) Class A61B 5/6824 (20130101) A61B 5/6826 (20130101) A61B 5/7264 (20130101) A61B 5/7282 (20130101) A61B 2562/0219 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/198 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/1723 (20130101) A61M 2230/63 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36067 (20130101) A61N 1/36139 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/63 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364003 | Boone et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | John M. Boone (Folsom, California); Thomas R. Yellen-Nelson (Del Mar, California) |
| ABSTRACT | A device and methods for performing a simulated CT biopsy on a region of interest on a patient. The device comprises a gantry (22) configured to mount an x-ray emitter (24) and CT detector (26) on opposing sides of the gantry, a motor (28) rotatably coupled to the gantry such that the gantry rotates horizontally about the region of interest, and a rotation of source high resolution x-ray detector (172) positioned adjacent the CT detector in between the CT detector and the x-ray emitter. |
| FILED | Friday, February 19, 2021 |
| APPL NO | 17/180549 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/03 (20130101) A61B 6/06 (20130101) A61B 6/12 (20130101) A61B 6/032 (20130101) A61B 6/037 (20130101) A61B 6/405 (20130101) A61B 6/0435 (20130101) A61B 6/469 (20130101) A61B 6/482 (20130101) Original (OR) Class A61B 6/488 (20130101) A61B 6/502 (20130101) A61B 6/584 (20130101) A61B 6/4028 (20130101) A61B 6/4417 (20130101) A61B 6/4423 (20130101) A61B 6/4452 (20130101) A61B 6/5235 (20130101) A61B 8/0825 (20130101) A61B 8/4416 (20130101) A61B 10/0041 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 2005/1061 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/70 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364011 | Herbst et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Elizabeth Bronwyn Herbst (Charlottesville, Virginia); John A. Hossack (Charlottesville, Virginia); Shiying Wang (Charlottesville, Virginia); F. William Mauldin, Jr. (Charlottesville, Virginia) |
| ABSTRACT | An apparatus can be used to generate acoustic imaging pulse sequences and receive corresponding echoes elicited by the acoustic imaging pulse sequences. An acoustic radiation force (ARF) pulse sequence can be generated to agitate a contrast medium in a tissue region between the acoustic imaging pulse sequences. A decorrelation between images corresponding to the received echoes can be determined. A weighting map can be applied to an image to weight a region of the image corresponding to a spatial location of the contrast medium using the determined decorrelation. In an example, the receiving of corresponding echoes elicited by the acoustic imaging pulse sequences can include receiving acoustic energy having a range of frequencies offset from a fundamental frequency associated with the acoustic imaging pulse sequences. An acoustic imaging pulse sequence can include a pulse having an inverted amplitude envelope with respect to another pulse included in the sequence. |
| FILED | Thursday, August 03, 2017 |
| APPL NO | 15/668404 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/14 (20130101) A61B 8/085 (20130101) A61B 8/461 (20130101) A61B 8/481 (20130101) Original (OR) Class A61B 8/4483 (20130101) A61B 8/5207 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/221 (20130101) A61K 49/223 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364035 | Shaker et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE MEDICAL COLLEGE OF WISCONSIN, INC. (Milwaukee, Wisconsin); UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin); University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Reza Shaker (Brookfield, Wisconsin); Anisa Shaker (Los Angeles, California) |
| ABSTRACT | A swallow exerciser device that exercises and thereby strengthens the muscles involved in swallowing includes a rigid shell, an adjustable fastener, and an inflatable pad. The rigid shell has a longitudinal dimension such that the shell extends above and below the larynx of the subject when the swallow exerciser device is positioned over the larynx of the subject. The adjustable fastener is dimensioned to secure the shell around a neck of the subject with the shell positioned over the larynx of the subject. The inflatable pad is connected to a proximal surface of the shell. The inflatable pad is dimensioned to apply resistance to force of at least one swallowing muscle of the subject when the shell positioned over the larynx of the subject and when the inflatable pad is in an inflated position. The swallow exerciser device can be used in a method for improving swallowing function in a subject. |
| FILED | Thursday, January 30, 2020 |
| APPL NO | 16/776698 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/132 (20130101) A61B 17/135 (20130101) A61B 17/1327 (20130101) Original (OR) Class A61B 2017/00827 (20130101) A61B 2090/065 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364042 | Maxwell et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Adam D. Maxwell (Ann Arbor, Michigan); Zhen Xu (Ann Arbor, Michigan); Hitinder S. Gurm (Ann Arbor, Michigan); Charles A. Cain (Ann Arbor, Michigan) |
| ABSTRACT | Methods for performing non-invasive thrombolysis with ultrasound using, in some embodiments, one or more ultrasound transducers to focus or place a high intensity ultrasound beam onto a blood clot (thrombus) or other vascular inclusion or occlusion (e.g., clot in the dialysis graft, deep vein thrombosis, superficial vein thrombosis, arterial embolus, bypass graft thrombosis or embolization, pulmonary embolus) which would be ablated (eroded, mechanically fractionated, liquefied, or dissolved) by ultrasound energy. The process can employ one or more mechanisms, such as of cavitational, sonochemical, mechanical fractionation, or thermal processes depending on the acoustic parameters selected. This general process, including the examples of application set forth herein, is henceforth referred to as “Thrombolysis.” |
| FILED | Tuesday, March 05, 2019 |
| APPL NO | 16/293394 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/0536 (20130101) A61B 8/00 (20130101) A61B 8/08 (20130101) A61B 8/485 (20130101) A61B 17/2258 (20130101) A61B 17/22004 (20130101) Original (OR) Class A61B 2017/00154 (20130101) A61B 2017/00172 (20130101) A61B 2017/00778 (20130101) A61B 2017/22001 (20130101) A61B 2017/22008 (20130101) A61B 2017/22088 (20130101) A61B 2017/22089 (20130101) A61B 2090/378 (20160201) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/0092 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364105 | Schwartz et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Jeffrey Schwartz (Princeton, New Jersey); Jean E. Schwarzbauer (Princeton, New Jersey); Casey M. Jones (Portland, Oregon); Patrick E. Donnelly (Lawrenceville, New Jersey); Stephen B. Bandini (Newton, Massachusetts); Shivani Singh (Princeton, New Jersey) |
| ABSTRACT | The present invention provides tissue scaffolds, methods of generating such scaffolds, and methods of use of such scaffolds to generate aligned and functional neural tissues for use in methods including regenerative medicine, wound repair and transplantation. |
| FILED | Wednesday, October 05, 2016 |
| APPL NO | 15/767616 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/0077 (20130101) Original (OR) Class A61F 2002/0086 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/02 (20130101) A61L 27/06 (20130101) A61L 27/10 (20130101) A61L 27/16 (20130101) A61L 27/24 (20130101) A61L 27/047 (20130101) A61L 27/227 (20130101) A61L 27/306 (20130101) A61L 27/383 (20130101) A61L 27/3633 (20130101) A61L 27/3834 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) C12N 2533/10 (20130101) C12N 2533/12 (20130101) C12N 2533/30 (20130101) C12N 2533/90 (20130101) C12N 2535/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364118 | Kheradvar |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Arash Kheradvar (Irvine, California) |
| ABSTRACT | Some embodiments relate to Some embodiments relate to an integrated ultrasound guided delivery system for positioning or repositioning of a transcatheter heart valve including: a delivery catheter coupled to the transcatheter heart valve, and an intravascular ultrasound (IVUS) catheter operably coupled to the delivery catheter, wherein the IVUS catheter includes an ultrasound transducer tip that is aligned with a base of leaflets of the transcatheter heart valve. Also disclosed is a method for positioning or repositioning a transcatheter heart valve at a target site in a subject including: providing an integrated ultrasound guided delivery system as disclosed herein; advancing the transcatheter heart valve in the vicinity of a native valve, viewing the native valve and the target site in real-time with the IVUS catheter, and deploying the transcatheter heart valve at the target site aiming to maintain a conformal placement within the native valve annulus, thereby avoiding or minimizing paravalvular leak. |
| FILED | Tuesday, July 10, 2018 |
| APPL NO | 16/031916 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0066 (20130101) A61B 5/0084 (20130101) A61B 5/6852 (20130101) A61B 8/12 (20130101) A61B 8/466 (20130101) A61B 8/0883 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2418 (20130101) A61F 2/2427 (20130101) Original (OR) Class A61F 2/2436 (20130101) A61F 2/2439 (20130101) A61F 2220/0091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364182 | Deng et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | Yang Deng (New Haven, Connecticut); Asiri Ediriwickrema (Cary, North Carolina); William M. Saltzman (New Haven, Connecticut) |
| ABSTRACT | Core-shell particles and methods of making and using thereof are described herein. The core is formed of or contains one or more hydrophobic materials or more hydrophobic materials. The shell is formed of or contains hyperbranched polyglycerol (HPG). The HPG coating can be modified to adjust the properties of the particles. Unmodified HPG coatings impart stealth properties to the particles which resist non-specific protein absorption and increase circulation in the blood. The hydroxyl groups on the HPG coating can be chemically modified to form functional groups that react with functional groups and adhere the particles to tissue, cells, or extracellular materials, such as proteins. |
| FILED | Monday, March 25, 2019 |
| APPL NO | 16/363823 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/90 (20130101) A61K 8/0241 (20130101) Original (OR) Class A61K 9/0014 (20130101) A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 9/1647 (20130101) A61K 9/5031 (20130101) A61K 9/5146 (20130101) A61K 9/5153 (20130101) A61K 31/427 (20130101) A61K 31/4178 (20130101) A61K 31/4745 (20130101) A61K 47/34 (20130101) A61K 2800/412 (20130101) A61K 2800/413 (20130101) A61K 2800/624 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 17/04 (20130101) Acyclic or Carbocyclic Compounds C07C 59/06 (20130101) C07C 59/08 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 83/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364222 | Strum et al. |
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| APPLICANT(S) | G1 Therapeutics, Inc. (Research Triangle Park, North Carolina); The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | G1 Therapeutics, Inc. (Research Triangle Park, North Carolina) |
| INVENTOR(S) | Jay C. Strum (Hillsborough, North Carolina); Gregory R. Thatcher (Urbana, Illinois); Rui Xiong (Urbana, Illinois); Jiong Zhao (Urbana, Illinois); Debra A. Tonetti (Urbana, Illinois) |
| ABSTRACT | Compositions, combinations and methods comprising a CDK4/6 inhibitor of Formula D with a selective estrogen receptor downregulator of Formula A, B or C that are advantageous for the treatment of abnormal cellular proliferation, including a cancer or a tumor. |
| FILED | Tuesday, July 02, 2019 |
| APPL NO | 16/460502 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/381 (20130101) Original (OR) Class A61K 31/519 (20130101) A61K 31/5377 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364231 | Saha et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Kansas (Lawrence, Kansas); BCN Biosciences L.L.C. (Inglewood, California) |
| ASSIGNEE(S) | University of Kansas (Lawrence, Kansas); BCN Biosciences L.L.C. (Inglewood, California) |
| INVENTOR(S) | Subhrajit Saha (Overland Park, Kansas); Andrew J. Norris (Los Angeles, California) |
| ABSTRACT | The present disclosure is directed to method of treatment for treating or ameliorating various conditions caused by radiation exposure such as RIGS, enteritis, oral mucositis, mucositis, and proctitis by the administration of a compound Yel002/BCN057 or an analog thereof. |
| FILED | Friday, May 08, 2020 |
| APPL NO | 16/870864 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4704 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364238 | Zisman |
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| APPLICANT(S) | Pulmokine, Inc. (Troy, New York) |
| ASSIGNEE(S) | PULMOKINE, INC. (Troy, New York) |
| INVENTOR(S) | Lawrence S. Zisman (Slingerlands, New York) |
| ABSTRACT | The present disclosure describes a method of treating pulmonary disorders, such as pulmonary arterial hypertension, using a combination of a PDGF receptor kinase inhibitor, PDEV inhibitor, and an endothelin receptor antagonist. The compounds can inhibit cell growth and proliferation and target the underlying pathology of PAH. |
| FILED | Friday, September 20, 2019 |
| APPL NO | 16/578084 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0075 (20130101) A61K 31/497 (20130101) Original (OR) Class A61K 31/505 (20130101) A61K 31/4985 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/12 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364253 | Acharya et al. |
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| APPLICANT(S) | AyuVis Research, Inc. (Fort Worth, Texas) |
| ASSIGNEE(S) | AYUVIS RESEARCH, INC. (Fort Worth, Texas) |
| INVENTOR(S) | Suchismita Acharya (Euless, Texas); Pragnya Das (Secane, Pennsylvania); Beamon Agarwal (Secane, Pennsylvania) |
| ABSTRACT | The present invention includes novel compositions and methods for treating comprising a compound with the Formula I: where n=0-5; X═NH, O, S, CH2; Y=Phenyl, a phenyl group substituted with at least one methyl, a phenyl group substituted with at least one nitro, a phenyl group substituted with at least one nitrogen, a phenyl group substituted with at least one boron, aryl, substituted aryl, heteroaryl, four to six membered cycloalkyl, four to six membered heterocycloalkyl; R═H, C(O)R2, SO2R2; R1═H, C(O)R2, SO2R2; R2=Ethyl, methyl, isopropyl, n-propyl, t-butyl, n-butyl, NH2, NR3R4, R3, R4=Ethyl, methyl, isopropyl, n-propyl, t-butyl, n-butyl, three to six membered cycloalkyl and Z═NH, O, S, CH2 or none, wherein the amount of the compound is selected to either inhibit or activate the immune response. |
| FILED | Tuesday, July 02, 2019 |
| APPL NO | 16/460211 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0043 (20130101) A61K 9/0073 (20130101) A61K 31/702 (20130101) Original (OR) Class A61K 31/7034 (20130101) A61K 31/7036 (20130101) A61K 31/7048 (20130101) A61K 31/7056 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364258 | Terek et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rhode Island Hospital (Providence, Rhode Island) |
| ASSIGNEE(S) | Rhode Island Hospital (Providence, Rhode Island) |
| INVENTOR(S) | Richard Terek (Providence, Rhode Island); Qian Chen (Barrington, Rhode Island); Xiaojuan Sun (Barrington, Rhode Island) |
| ABSTRACT | This invention is directed to, inter alia, compositions and methods for restoring normal microRNA (miR) expression in chondrosarcoma cells as well as methods for treating and diagnosing chondrosarcoma in individuals in need thereof. |
| FILED | Monday, March 06, 2017 |
| APPL NO | 16/082222 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/5184 (20130101) A61K 31/395 (20130101) A61K 31/7105 (20130101) Original (OR) Class A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364269 | Becattini et al. |
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| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York) |
| INVENTOR(S) | Simone Becattini (New York, New York); Eric Pamer (Montclair, New Jersey); Sohn Kim (New York, New York) |
| ABSTRACT | The disclosure relates to a therapeutic composition for treating L. monocytogenes infection or L. monocytogenes colonization, the composition including at least one, at least two, at least three, or all of an isolated C. saccharogumia bacteria, an isolated C. ramosum bacteria, an isolated C. hathewayi bacteria, and/or an isolated B. producta bacteria in a formulation suitable for administration to a subject. The disclosure further provides similar compositions lacking an isolated C. saccharogumia bacteria. The disclosure additionally provides methods of treating L. monocytogenes infection or colonization using such compositions. |
| FILED | Tuesday, November 19, 2019 |
| APPL NO | 16/688632 |
| ART UNIT | 1699 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0031 (20130101) A61K 9/0056 (20130101) A61K 35/742 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364278 | Hawiger et al. |
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| FUNDED BY |
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| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| INVENTOR(S) | Jack J. Hawiger (Nashville, Tennessee); Jozef Zienkiewicz (Nashville, Tennessee) |
| ABSTRACT | The present invention relates to compositions and methods for treating autoimmune, microbial, metabolic, neoplastic, and posttraumatic diseases mediated by inflammation in a subject. Compositions and methods including at least one importin beta-selective nuclear transport modifier (NTM) and/or at least one importin alpha-selective NTM, and/or at least one importin alpha-specific NTM, and/or at least one inhibitor of importin alpha and importin beta complex formation may be administered to a subject to modulate the transport of transcription factors, mediated by nuclear import adaptors, into the nucleus of a cell resulting in a decrease or abrogation of inflammation. |
| FILED | Monday, February 24, 2020 |
| APPL NO | 16/799350 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/167 (20130101) A61K 31/167 (20130101) A61K 31/192 (20130101) A61K 31/192 (20130101) A61K 38/12 (20130101) A61K 38/16 (20130101) Original (OR) Class A61K 38/16 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) Peptides C07K 14/47 (20130101) C07K 14/50 (20130101) C07K 14/4702 (20130101) C07K 2319/00 (20130101) C07K 2319/09 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364295 | Sampson et al. |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | John H Sampson (Durham, North Carolina); Duane A Mitchell (Durham, North Carolina) |
| ABSTRACT | The present invention relates to compositions, methods, and kits for eliciting an immune response to at least one CMV antigen expressed by a cancer cell, in particular for treating and preventing cancer. CMV determination methods, compositions, and kits also are provided. |
| FILED | Thursday, July 23, 2020 |
| APPL NO | 16/937171 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) A61K 39/12 (20130101) A61K 39/39 (20130101) A61K 39/245 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2039/53 (20130101) A61K 2039/5154 (20130101) A61K 2039/5156 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/16122 (20130101) C12N 2710/16134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364297 | Kobayashi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Hisataka Kobayashi (Laurel, Maryland); Peter Choyke (Rockville, Maryland) |
| ABSTRACT | The present disclosure relates to compositions and methods of killing cells. In particular examples, the method includes contacting a cell having a cell surface protein with a therapeutically effective amount of an antibody-IR700 molecule, wherein the antibody specifically binds to the cell surface protein, such as a tumor-specific antigen on the surface of a tumor cell. The cell is subsequently irradiated, such as at a wavelength of 660 to 740 nm at a dose of at least 1 J cm−2. The cell is also contacted with one or more therapeutic agents (such as an anti-cancer agent), for example about 0 to 8 hours after irradiating the cell, thereby killing the cell. Also provided are methods of imaging cell killing in real time, using fluorescence lifetime imaging. Also provided are wearable devices that include an article of clothing, jewelry, or covering; and an NIR LED incorporated into the article, which can be used with the disclosed methods. |
| FILED | Monday, November 25, 2019 |
| APPL NO | 16/694761 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 13/0002 (20130101) A41D 2400/32 (20130101) Personal Adornments, e.g Jewellery; Coins A44C 15/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 31/704 (20130101) A61K 41/0071 (20130101) A61K 45/06 (20130101) Original (OR) Class A61K 47/6803 (20170801) A61K 47/6869 (20170801) A61K 49/0032 (20130101) A61K 49/0058 (20130101) A61K 2039/505 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/30 (20130101) C07K 16/32 (20130101) C07K 16/2863 (20130101) C07K 16/3069 (20130101) C07K 2317/24 (20130101) C07K 2317/73 (20130101) C07K 2317/77 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364298 | Kobayashi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Hisataka Kobayashi (Laurel, Maryland); Peter Choyke (Rockville, Maryland) |
| ABSTRACT | The present disclosure relates to compositions and methods of killing cells in vitro or in vivo. In particular examples, the method includes contacting a cell having a cell surface protein with a therapeutically effective amount of an antibody-IR700 molecule, wherein the antibody specifically binds to the cell surface protein. In particular examples the antibody recognizes a tumor-specific antigen on the surface of a tumor cell. The cell is subsequently irradiated, such as at a wavelength of 660 to 740 nm at a dose of at least 1 J cm−2, thereby killing the cell. Also provided are wearable devices that include an article of clothing, jewelry, or covering; and an NIR LED incorporated into the article, which can be used with the disclosed methods. |
| FILED | Tuesday, November 26, 2019 |
| APPL NO | 16/695674 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 13/0002 (20130101) A41D 2400/32 (20130101) Personal Adornments, e.g Jewellery; Coins A44C 15/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 31/704 (20130101) A61K 41/0071 (20130101) A61K 45/06 (20130101) Original (OR) Class A61K 47/6803 (20170801) A61K 47/6869 (20170801) A61K 49/0032 (20130101) A61K 49/0058 (20130101) A61K 2039/505 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/30 (20130101) C07K 16/32 (20130101) C07K 16/2863 (20130101) C07K 16/3069 (20130101) C07K 2317/24 (20130101) C07K 2317/73 (20130101) C07K 2317/77 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364304 | Mirkin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Chad A. Mirkin (Wilmette, Illinois); SonBinh T. Nguyen (Evanston, Illinois); Resham J. Banga (Evanston, Illinois) |
| ABSTRACT | Methods of preparing crosslinked spherical nucleic acids (SNAs) using thermoresponsive traceless templates, such as PEO-PPO-PEO block copolymers. The crosslinks can be added between oligonucleotides within the same SNA or oligonucleotides between multiple different SNAs. |
| FILED | Friday, August 25, 2017 |
| APPL NO | 16/328025 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/711 (20130101) A61K 31/7105 (20130101) A61K 47/6917 (20170801) Original (OR) Class Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) C07H 21/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/88 (20130101) C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2310/141 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364306 | Shayakhmetov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ADCURE BIOTECHNOLOGIES, LLC. (Snellville, Georgia) |
| ASSIGNEE(S) | ADCURE BIOTECHNOLOGIES, LLC (Snellville, Georgia) |
| INVENTOR(S) | Dmitry M. Shayakhmetov (Snellville, Georgia); Nelson C. Di Paolo (Avondale Estates, Georgia) |
| ABSTRACT | The present disclosure describes the generation and the use of Ad variants (Ad) possessing any combination of mutations in genes that code for the hexon, penton, fiber, and non-structural proteins, where simultaneous modification of hexon and penton are made to avoid the trapping of Ad in the liver and to reduce toxicity after intravascular virus administration. Such liver de-targeted Ad can be useful tool for selective and specific gene delivery to extra-hepatic tissues and cells, including disseminated metastatic cancer cells. |
| FILED | Tuesday, July 02, 2019 |
| APPL NO | 16/460160 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/76 (20130101) A61K 35/761 (20130101) A61K 48/00 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 43/00 (20180101) Peptides C07K 14/005 (20130101) C07K 14/075 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 7/06 (20130101) C12N 15/86 (20130101) C12N 15/8616 (20130101) C12N 2710/00043 (20130101) C12N 2710/00061 (20130101) C12N 2710/10021 (20130101) C12N 2710/10322 (20130101) C12N 2710/10332 (20130101) C12N 2710/10333 (20130101) C12N 2710/10334 (20130101) C12N 2710/10345 (20130101) C12N 2810/405 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364502 | Meldrum et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Deirdre Meldrum (Phoenix, Arizona); Laimonas Kelbauskas (Gilbert, Arizona); Wacey Teller (Mesa, Arizona); Meryl Rodrigues (Tempe, Arizona); Hong Wang (Tempe, Arizona); Ganquan Song (Mesa, Arizona); Yanqing Tian (Tempe, Arizona); Fengyu Su (Tempe, Arizona); Xiangxing Kong (Tempe, Arizona); Liqiang Zhang (Chandler, Arizona) |
| ABSTRACT | A microfluidic device includes a first substrate including at least one microfluidic channel and a plurality of microwells, as well as a cooperating second substrate defining multiple split-walled cell trap structures that are registered with and disposed within the plurality of microwells. A method for performing an assay includes flowing cells and a first aqueous medium into a plurality of microwells of a microfluidic device, wherein each microwell includes a cell trap structure configured to trap at least one cell. The method further comprises flowing a nonpolar fluid with low permeability for analytes of interest through a microfluidic channel to flush a portion of the first aqueous medium from the microfluidic channel while retaining another portion of the first aqueous medium and at least one cell within each microwell. Surface tension at a non-polar/polar medium interface prevents molecule exchange between interior and exterior portions of microwells. |
| FILED | Monday, November 14, 2016 |
| APPL NO | 15/774558 |
| ART UNIT | 1796 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) Original (OR) Class B01L 2200/0668 (20130101) B01L 2300/18 (20130101) B01L 2300/0663 (20130101) B01L 2300/0864 (20130101) B01L 2300/0893 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364629 | Sefati et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Shahriar Sefati (Baltimore, Maryland); Mehran Armand (Maple Lawn, Maryland); Iulian Iordachita (Baltimore, Maryland) |
| ABSTRACT | A flexible manipulator apparatus includes an elongate flexible manipulator having a sensor, a user output device configured to provide sensory outputs to the user, and processing circuitry. The flexible manipulator may be movable to form a curve in the flexible manipulator. The processing circuitry may be configured to receive captured sensor data from the sensor during movement of the flexible manipulator, and determine a collision likelihood score based on application of the captured sensor data to a collision detection model used for position estimation. The collision detection model may be based on an empirical data training for the flexible manipulator that includes training sensor data from the sensor and training image data of positions of the flexible manipulator. The processing circuitry may be configured to control the user output device based on the collision likelihood score to provide a collision alert sensory output to the user. |
| FILED | Wednesday, February 26, 2020 |
| APPL NO | 16/801272 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/104 (20130101) B25J 9/163 (20130101) Original (OR) Class B25J 9/1666 (20130101) B25J 9/1697 (20130101) B25J 18/06 (20130101) B25J 19/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11365177 | Spiegelman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Bruce M. Spiegelman (Waban, Massachusetts); Jonathan Z. Long (Menlo Park, California); Hua Lin (Jupiter, Florida); Theodore Kamenecka (Palm Beach Gardens, Florida); Patrick Griffin (Jupiter, Florida) |
| ABSTRACT | Uncoupling of respiration is a well-recognized process that increases respiration and heat production in cells. Provided herein are chemical uncouplers of respiration that are compounds of Formula (I). Also provided are methods for preventing or treating metabolic disorders and modulating metabolic processes using compound of Formula (I). |
| FILED | Thursday, November 29, 2018 |
| APPL NO | 16/768211 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/02 (20180101) Heterocyclic Compounds C07D 209/42 (20130101) C07D 211/60 (20130101) Original (OR) Class C07D 215/48 (20130101) C07D 217/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11365183 | Schunck et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MAX-DELBRUECK-CENTRUM FUER MOLEKULARE MEDIZIN (Berlin, Germany); BOARD OF REGENTS OF UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | MAX-DELBRUECK-CENTRUM FUER MOLEKULARE MEDIZIN (Berlin, Germany); BOARD OF REGENTS OF UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Wolf-Hagen Schunck (Berlin, Germany); Gerd Wallukat (Berlin, Germany); Robert Fischer (Berlin, Germany); Cosima Arnold (Ulm, Germany); Dominik N. Mueller (Berlin, Germany); Narender Puli (Dallas, Texas); John R. Falck (Dallas, Texas) |
| ABSTRACT | The present invention provides compounds (n-3 PUFA derivatives) of formula (I): that modulate conditions associated with cardiac damage, especially cardiac arrhythmias. |
| FILED | Monday, March 25, 2019 |
| APPL NO | 16/363022 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 233/09 (20130101) C07C 233/47 (20130101) C07C 233/49 (20130101) C07C 235/28 (20130101) C07C 235/76 (20130101) C07C 275/14 (20130101) C07C 275/16 (20130101) C07C 275/20 (20130101) Heterocyclic Compounds C07D 303/38 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11365195 | Newman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| INVENTOR(S) | Amy Hauck Newman (Phoenix, Maryland); JoLynn Barbara Giancola (Boardman, Ohio); Rachel D. Slack (Baltimore, Maryland) |
| ABSTRACT | Disclosed herein are a series of modafinil analogue compounds that bind with moderate to high affinity to the dopamine (DA) transporter (DAT) and several analogues also having affinity for the serotonin (5-HT) transporter (SERT) and/or sigma-1 receptor. Employing aminopiperidine, piperidineamino, spirobicyclodiaza, or substituted piperazine functional groups, desired dopamine transporter affinity has been retained along with improved metabolic stability over unsubstituted piperazine ring analogues. Importantly, these compounds have no predicted addictive liability. Also disclosed are methods for treating substance use disorders as well as other neuropsychiatric disorders such as ADHD, depression, narcolepsy, and cognitive impairment. |
| FILED | Monday, November 12, 2018 |
| APPL NO | 16/762998 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 211/58 (20130101) C07D 241/04 (20130101) C07D 471/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11365211 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The USA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); Alchem Laboratories Corporation (Alachua, Florida) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Lianhao Zhang (Alachua, Florida); Baburao Vishnuvajjala (Rockville, Maryland); Joel Morris (Rockville, Maryland); Robert Bahde (Gaithersburg, Maryland); Sergiy M. Denysenko (Gainesville, Florida); Omar Diego Lopez (Walkersville, Maryland); Donn Gregory Wishka (Middletown, Maryland) |
| ABSTRACT | Methods for stereoselective synthesis and manufacturing of 2′-deoxynucleosides, such as 2′-ribonucleosides, are disclosed. In some embodiments, the 2′-deoxynucleoside is a β-anomer of a 2′-deoxynucleoside having a 3′ α hydroxyl, 4′ β hydroxymethyl configuration. Nonlimiting examples of compounds prepared by the disclosed methods include 4′-thio-2′-deoxycytidine (T-dCyd) and 5-aza-4′-thio-2′-deoxycytidine (5-aza-T-dCyd; aza-T-dCyd; aza-T-dC). |
| FILED | Wednesday, January 30, 2019 |
| APPL NO | 16/966398 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/00 (20130101) Original (OR) Class C07H 23/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11365219 | Heath et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | James R. Heath (Pasadena, California); Rosemary Dyane Rohde (Pasadena, California); Arundhati Nag (Pasadena, California); Samir Das (Pasadena, California); Aiko Umeda (Pasadena, California) |
| ABSTRACT | Peptides having activity as protein binding agents are disclosed. The peptides have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein R, R1, L1, L2, G, M, Y1Y2 and SEQ are as defined herein. Methods associated with preparation and use of such peptides, as well as pharmaceutical compositions comprising such peptides, are also disclosed. |
| FILED | Monday, June 22, 2020 |
| APPL NO | 16/908204 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0032 (20130101) A61K 49/0041 (20130101) A61K 49/0043 (20130101) A61K 51/08 (20130101) A61K 51/088 (20130101) Peptides C07K 1/047 (20130101) C07K 5/06 (20130101) C07K 5/08 (20130101) C07K 5/10 (20130101) C07K 7/56 (20130101) C07K 7/64 (20130101) Original (OR) Class C07K 14/001 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) G01N 33/6842 (20130101) G01N 2333/912 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11365221 | Ware et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California) |
| ASSIGNEE(S) | Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California) |
| INVENTOR(S) | Carl Ware (Solana Beach, California); John Sedy (San Diego, California) |
| ABSTRACT | Ligand-specific HVEM variants, compositions comprising such variants, and methods of treating inflammatory diseases comprising administering such variants, are provided. |
| FILED | Monday, June 08, 2020 |
| APPL NO | 16/896009 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/03 (20130101) Original (OR) Class C07K 14/70578 (20130101) C07K 16/28 (20130101) C07K 2319/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11365231 | Wong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Altor BioScience, LLC (Culver City, California) |
| ASSIGNEE(S) | Altor BioScience, LLC (Culver City, California) |
| INVENTOR(S) | Hing C. Wong (Weston, Florida); Peter Rhode (Miami, Florida); Xiaoyun Zhu (Weston, Florida); Kai-Ping Han (Weston, Florida) |
| ABSTRACT | The instant invention provides soluble fusion protein complexes and IL-15 variants that have therapeutic and diagnostic use, and methods for making the proteins. The instant invention additionally provides methods of stimulating or suppressing immune responses in a mammal using the fusion protein complexes and IL-15 variants of the invention. |
| FILED | Wednesday, October 16, 2019 |
| APPL NO | 16/654958 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/1774 (20130101) A61K 38/1793 (20130101) A61K 38/2086 (20130101) Peptides C07K 14/5443 (20130101) Original (OR) Class C07K 14/7051 (20130101) C07K 14/7155 (20130101) C07K 16/18 (20130101) C07K 16/28 (20130101) C07K 2319/00 (20130101) C07K 2319/31 (20130101) C07K 2319/33 (20130101) C07K 2319/74 (20130101) C07K 2319/75 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/09 (20130101) C12N 15/62 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56977 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11365243 | Diamond et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Feinstein Institutes for Medical Research (Manhasset, New York) |
| ASSIGNEE(S) | The Feinstein Institutes for Medical Research (Manhasset, New York) |
| INVENTOR(S) | Betty A. Diamond (Bronx, New York); Simone Mader (Woodside, New York); Lior Brimberg (Bayside, New York); Peter Gregersen (Larchmont, New York) |
| ABSTRACT | Methods of diagnosis and methods of treatment and prevention for autism spectrum disorder are provided using decoy antigens to maternal brain-reactive antibodies. |
| FILED | Monday, April 20, 2020 |
| APPL NO | 16/852755 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/17 (20130101) A61K 38/177 (20130101) A61K 38/1709 (20130101) A61K 38/1774 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Peptides C07K 16/18 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 33/6896 (20130101) G01N 2800/28 (20130101) G01N 2800/38 (20130101) G01N 2800/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11365250 | Beutler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Bruce Beutler (Austin, Texas); Evan Nair-Gill (Austin, Texas); Xue Zhong (Austin, Texas); Jinglei Zhang (Austin, Texas); Pingping Wang (Austin, Texas) |
| ABSTRACT | The present disclosure generally relates to compositions and methods for cancer immunotherapy, as well as hematopoietic recovery following cancer treatment such as chemotherapy or irradiation. |
| FILED | Thursday, November 29, 2018 |
| APPL NO | 16/767152 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/28 (20130101) Original (OR) Class C07K 2317/52 (20130101) C07K 2317/565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11365412 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Cincinnati (Cincinnati, Ohio) |
| ASSIGNEE(S) | University of Cincinnati (Cincinnati, Ohio) |
| INVENTOR(S) | Yigang Wang (Cincinnati, Ohio); Wei Huang (Cincinnati, Ohio) |
| ABSTRACT | Inhibitors of miRNA-128 capable of promoting cardiomyocyte mitotic cell proliferation and methods effective for regeneration of heart tissue. |
| FILED | Thursday, April 05, 2018 |
| APPL NO | 16/500481 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0657 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/141 (20130101) C12N 2310/531 (20130101) C12N 2320/30 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11365413 | Campbell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Zachary T. Campbell (Plano, Texas); Theodore J. Price (Dallas, Texas) |
| ABSTRACT | The present disclosure describes chemically-stabilized RNA substrates that hybridize to poly-A binding protein (PABP) with high specificity in vitro, as well as their use in impairs nascent translation in a PABP-dependent mechanism in cells, thereby treating pain. |
| FILED | Thursday, August 22, 2019 |
| APPL NO | 16/547882 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/7023 (20130101) A61K 31/7125 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/315 (20130101) C12N 2310/321 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11365415 | Hromas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Robert A. Hromas (Gainesville, Florida); Elizabeth Williamson (Gainesville, Florida); Gayathri Srinivasan (Gainesville, Florida) |
| ABSTRACT | The subject invention provides a pharmaceutical composition comprising an inhibitory RNA (iRNA) that mediates sequence-specific degradation of the mRNA encoding Poly (ADP-ribose) polymerase 1 (PARP1) and methods of treating cancers by administering the pharmaceutical composition to a subject in need thereof. In one embodiment, the iRNA is miR-223, particularly, miR-223-3p or a modified miR-223-3p having substitutions and/or deletions in the sequence of miR-223-3p. In another embodiment, the cancer cells comprise one or more mutations in the genes that mediate homologous recombination DNA repair, for example, BRCA1 and/or BRCA2 genes. The cancer can be breast cancer, ovarian cancer, prostate cancer, pancreatic cancer or meso thelioma. Methods of treating cancer, for example, a cancer comprising BRCA1 and/or 2 mutations, using a combination of iRNA and a second cancer therapeutic are also provided. |
| FILED | Friday, April 14, 2017 |
| APPL NO | 16/093465 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 31/7068 (20130101) A61K 47/646 (20170801) A61K 48/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) Original (OR) Class C12N 2310/141 (20130101) C12N 2310/3513 (20130101) C12N 2320/31 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11365429 | Church et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | George M. Church (Brookline, Massachusetts); Prashant G. Mali (La Jolla, California); Luhan Yang (Somerville, Massachusetts) |
| ABSTRACT | A method of altering a eukaryotic cell is provided including transfecting the eukaryotic cell with a nucleic acid encoding RNA complementary to genomic DNA of the eukaryotic cell, transfecting the eukaryotic cell with a nucleic acid encoding an enzyme that interacts with the RNA and cleaves the genomic DNA in a site specific manner, wherein the cell expresses the RNA and the enzyme, the RNA binds to complementary genomic DNA and the enzyme cleaves the genomic DNA in a site specific manner. |
| FILED | Monday, April 29, 2019 |
| APPL NO | 16/397213 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/01 (20130101) C12N 15/10 (20130101) C12N 15/63 (20130101) C12N 15/81 (20130101) C12N 15/85 (20130101) Original (OR) Class C12N 15/87 (20130101) C12N 15/90 (20130101) C12N 15/102 (20130101) C12N 15/907 (20130101) C12N 15/1024 (20130101) C12N 15/8201 (20130101) C12N 2310/20 (20170501) C12N 2800/80 (20130101) C12N 2810/55 (20130101) Enzymes C12Y 301/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11365453 | de Vlaminck et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Iwijn de Vlaminck (Stanford, California); Michael Kertesz (Menlo Park, California); Kiran Kaur Khush (Stanford, California); Mark Alec Kowarsky (Kowarsky, Australia); Lance Martin (Half Moon Bay, California); Stephen R. Quake (Stanford, California); Hannah Valantine (Stanford, California) |
| ABSTRACT | Methods, devices, compositions and kits are provided for analysis of the microbiome or individual components thereof in an individual. The methods find use in a determination of infection, in analysis of the microbiome structure, in determining the immunocompetence of an individual, and the like. In some embodiments of the invention, the individual is treated with an therapeutic regimen, e.g. drugs, diet, radiation therapy, and the like. |
| FILED | Monday, June 14, 2021 |
| APPL NO | 17/347138 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) C12Q 1/701 (20130101) C12Q 1/705 (20130101) Original (OR) Class C12Q 1/6883 (20130101) C12Q 1/6895 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) G16B 20/20 (20190201) G16B 30/00 (20190201) G16B 30/10 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11366093 | Viola et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HEMOSONICS, LLC (Charlottesville, Virginia) |
| ASSIGNEE(S) | HEMOSONICS, LLC (Charlottesville, Virginia) |
| INVENTOR(S) | Francesco Viola (Chapel Hill, North Carolina); Timothy Higgins (Charlottesville, Virginia); Andrew Homyk (Charlottesville, Virginia); F. Scott Corey (Baltimore, Maryland); Franklin F. Regan (Charlottesville, Virginia); William F. Walker (Charlottesville, Virginia); David Bryant (Charlottesville, Virginia); Thomas Givens (Rougemont, North Carolina); Cynthia Ann Lloyd (Durham, North Carolina) |
| ABSTRACT | A disposable system, in some embodiments, includes a multi-channel or multi-chamber test cartridge device configured to operate with a testing system for evaluation of hemostasis in a subject by in vitro evaluation of a test sample from the subject. The disposable system, in some embodiments, is configured to interrogate the test sample to evaluate clot stiffness, strength, or other mechanical properties of the test sample to assess the function of various physiological processes occur during coagulation and/or dissolution of the resulting clot. |
| FILED | Friday, April 20, 2018 |
| APPL NO | 15/958875 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502 (20130101) B01L 2300/0825 (20130101) B01L 2300/0838 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/86 (20130101) G01N 33/4905 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11366100 | Roberts et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Thomas M. Roberts (Cambridge, Massachusetts); Haoxuan Tong (Cambridge, Massachusetts); Jean Zhao (Brookline, Massachusetts); John Blenis (New York, New York) |
| ABSTRACT | The present invention is based, in part, on the identification of novel FI.3K-mTORCI-S6K 1 signaling pathway biomarkers predictive of responsiveness to anti-cancer therapies. |
| FILED | Thursday, February 12, 2015 |
| APPL NO | 15/116319 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/58 (20130101) A61K 45/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) C12Q 2600/136 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) Original (OR) Class G01N 33/5088 (20130101) G01N 33/57492 (20130101) G01N 2333/91215 (20130101) G01N 2500/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11366113 | Hall et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | John Clayton Hall (Baltimore, Maryland); Livia Casciola-Rosen (Baltimore, Maryland); Antony Rosen (Baltimore, Maryland) |
| ABSTRACT | The present inventors identified a subpopulation of genes induced by type I and type II IFNs in a human submandibular gland (HSG) epithelial cell line. Unexpectedly, it was found that the majority of genes that are highly up-regulated by IFN-α are also highly induced by IFN-γ. In contrast, there was a substantial group of genes that are highly induced by IFN-γ only. In target tissues, this identified subpopulation of genes and probes allow different IFN patterns to be discerned, enabling more precise molecular classification of patient subpopulations. The identified gene probes are useful for selecting and monitoring therapy, and for defining efficacy of novel agents in the autoimmune rheumatic diseases. |
| FILED | Tuesday, May 08, 2018 |
| APPL NO | 15/973688 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) Original (OR) Class G01N 33/6842 (20130101) G01N 33/6866 (20130101) G01N 33/6893 (20130101) G01N 2800/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11366115 | Kotton et al. |
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| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Darrell N. Kotton (Newton, Massachusetts); Finn Hawkins (Boston, Massachusetts) |
| ABSTRACT | Provided herein are methods and compositions relating, in part, to the generation and isolation of human lung progenitor cells from pluripotent stem cells. |
| FILED | Tuesday, July 02, 2019 |
| APPL NO | 16/460461 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/007 (20130101) A61K 9/19 (20130101) A61K 35/42 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0689 (20130101) C12N 2501/117 (20130101) C12N 2501/119 (20130101) C12N 2501/155 (20130101) C12N 2501/599 (20130101) C12N 2501/999 (20130101) C12N 2506/04 (20130101) C12N 2506/45 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) Original (OR) Class G01N 2333/4703 (20130101) G01N 2333/70596 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11366121 | Ghosh |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Pradipta Ghosh (San Diego, California) |
| ABSTRACT | Research tool assay for identifying a specific modulator of GNAI, compositions and methods of use. The assay includes combining a drug candidate with GNAI and a C-terminal GIV peptide and determining if the drug candidate inhibits GNAI interaction with the C-terminal GIV peptide; and combining the drug candidate with GNAI and a DAPLE peptide and determining if the drug candidate inhibits GNAI interaction with DAPLE peptide. Also provided are compositions and methods of treatment relating to the same. |
| FILED | Thursday, February 22, 2018 |
| APPL NO | 16/487462 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/185 (20130101) Peptides C07K 7/08 (20130101) C07K 14/47 (20130101) C07K 14/723 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6845 (20130101) Original (OR) Class G01N 2333/726 (20130101) G01N 2500/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11367180 | Coudray et al. |
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| FUNDED BY |
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| APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Nicolas Coudray (New York, New York); Paolo Santiago Ocampo (Brooklyn, New York); Andre L. Moreira (New York, New York); Narges Razavian (New York, New York); Aristotelis Tsirigos (Hicksville, New York) |
| ABSTRACT | Systems and methods for classification and mutation prediction from histopathology images using deep learning. In particular, the examples described herein utilize lung cancer as an example, in particular adenocarcinoma (LUAD) and squamous cell carcinoma (LUSC) as two subtypes of lung cancer to identify and distinguish between. |
| FILED | Wednesday, December 11, 2019 |
| APPL NO | 16/711199 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57423 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 2207/20084 (20130101) G06T 2207/30061 (20130101) G06T 2207/30096 (20130101) Image or Video Recognition or Understanding G06V 20/698 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11367185 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Lifeng Yu (Byron, Minnesota); Hao Gong (Rochester, Minnesota); Shuai Leng (Rochester, Minnesota); Cynthia H. McCollough (Byron, Minnesota) |
| ABSTRACT | A fully image-based framework for CT image, or other medical image, quality evaluation and virtual clinical trial using deep-learning techniques is provided. This framework includes deep learning-based noise insertion, lesion insertion, and model observer, which enable efficient, objective, and quantitative image quality evaluation and virtual clinical trial directly performed on patient images. |
| FILED | Monday, July 13, 2020 |
| APPL NO | 16/927598 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 2207/10081 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/20221 (20130101) G06T 2207/30096 (20130101) G06T 2207/30108 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 15/00 (20180101) G16H 30/40 (20180101) G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11367264 | Trinh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Viet Trinh (Santa Cruz, California); Roberto Manduchi (Santa Cruz, California) |
| ABSTRACT | A computer implemented method or system including a map conversion toolkit and a map Population toolkit. The map conversion toolkit allows one to quickly trace the layout of a floor plan, generating a file (e.g., GeoJSON file) that can be rendered in two dimensions (2D) or three dimensions (3D) using web tools such as Mapbox. The map population toolkit takes the scan (e.g., 3D scan) of a room in the building (taken from an RGB-D camera), and, through a semi- automatic process, generates individual objects, which are correctly dimensioned and positioned in the (e.g., GeoJSON) representation of the building. In another example, a computer implemented method for diagraming a space comprises obtaining a layout of the space; and annotating or decorating the layout with meaningful labels that are translatable to glanceable visual signals or audio signals. |
| FILED | Friday, July 17, 2020 |
| APPL NO | 16/932438 |
| ART UNIT | 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 17/20 (20130101) G06T 19/20 (20130101) Original (OR) Class G06T 2219/004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11367539 | Zheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | Board of Trustees, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Yuebing Zheng (Austin, Texas); Jingang Li (Austin, Texas) |
| ABSTRACT | Disclosed herein are methods of manipulating particles on solid substrates via optothermally-gated photon nudging. |
| FILED | Tuesday, November 24, 2020 |
| APPL NO | 17/103240 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11368116 | Trumper et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | David L. Trumper (Plaistow, New Hampshire); Benjamin Weinreb (Boston, Massachusetts) |
| ABSTRACT | A motor system can include a bearingless stator having a plurality of magnetic windings including rotation windings and suspension windings; a dipole interior permanent magnet (IPM) rotor positioned within the stator, the rotor having a plurality of permanent magnets disposed within a cylindrical structure; one or more position sensors to measure radial and angular position of the rotor; and a controller configured to receive measurements from the one or more position sensors and to generate current commands for the stator to excite the rotation windings to generate torque and to excite the suspension windings to stabilize the rotor within the stator. |
| FILED | Thursday, May 27, 2021 |
| APPL NO | 17/331712 |
| ART UNIT | 2846 — Electrical Circuits and Systems |
| CURRENT CPC | Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 21/18 (20160201) H02P 21/22 (20160201) Original (OR) Class H02P 2207/05 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11368336 | Porter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | George Porter (San Diego, California); William Mellette (San Diego, California) |
| ABSTRACT | An apparatus for interfacing with a circuit switched network may be configured to detect when a data carrier signal from a circuit switched network is offline. While the data carrier signal from the circuit switched network is offline, the apparatus may send, to a network element coupled with the circuit switched network via the apparatus, control packets indicating that the data carrier signal is offline. The apparatus may further maintain an active data carrier signal between the apparatus and the network device by sending, to the network element, protocol idle frames. The apparatus may buffer, at the apparatus, packets sent from the network element to the circuit switched network. Once the data carrier signal is restored, the apparatus may send, to the circuit switched network, control packets indicating that the data carrier signal is online and the packet buffered at the apparatus while the data carrier signal is offline. |
| FILED | Tuesday, July 10, 2018 |
| APPL NO | 16/629781 |
| ART UNIT | 2472 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 12/66 (20130101) Original (OR) Class H04L 45/026 (20130101) H04L 49/552 (20130101) H04L 49/3036 (20130101) H04L 69/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11364142 | Myers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vivonics, Inc. (Bedford, Massachusetts) |
| ASSIGNEE(S) | Vivonics, Inc. (Bedford, Massachusetts); Liberating Technologies, Inc. (Holliston, Massachusetts) |
| INVENTOR(S) | Ryan Myers (North Andover, Massachusetts); Kristen LeRoy (Waltham, Massachusetts); Ian Cohen (Boulder, Colorado); Gordon B. Hirschman (Cohoes, New York); Thane R. Hunt (Colchester, Connecticut); Kevin E. Keough (Sharon, Massachusetts); Carlos Martinez Luna (Boylston, Massachusetts); Todd R. Farrell (Waltham, Massachusetts); Jennifer L. Johansson (Wayland, Massachusetts); Brendan LaBrecque (Middleton, Massachusetts) |
| ABSTRACT | A prosthetic socket cooling system and method includes a thermally conductive heat spreader including a curved shaped portion configured to maximize contact with a residual limb of a user. A heat extraction subsystem is coupled through a wall of the prosthetic socket and to the thermally conductive heat spreader and is configured to maintain a desired temperature inside the prosthetic socket. |
| FILED | Thursday, December 06, 2018 |
| APPL NO | 16/211974 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/60 (20130101) A61F 2/80 (20130101) A61F 2/7812 (20130101) A61F 5/01 (20130101) A61F 7/00 (20130101) Original (OR) Class A61F 2007/0051 (20130101) A61F 2007/0067 (20130101) A61F 2007/0075 (20130101) A61F 2007/0078 (20130101) A61F 2007/0093 (20130101) A61F 2007/0095 (20130101) A61F 2007/0096 (20130101) A61F 2007/0228 (20130101) A61F 2007/0246 (20130101) A61F 2007/0247 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 2230/00 (20130101) F28F 2255/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364239 | Singh |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CFD Research Corporation (Huntsville, Alabama) |
| ASSIGNEE(S) | CFD RESEARCH CORPORATION (Huntsville, Alabama) |
| INVENTOR(S) | Narender Singh (Madison, Alabama) |
| ABSTRACT | A method for providing a therapy to a subject that has been exposed to an Aflatoxin B1 can include administering a compound having a structure of Formula 1 to the subject after exposure to the Aflatoxin B1: wherein: R1, R2, R3, R4, R5 and/or R6 are each individually a chemical moiety and n is 1, 2, 3, 4, or 5. The compound can be Amprenavir or a derivative thereof, prodrug thereof, salt thereof, or stereoisomer thereof, or having any chirality at any chiral center, or tautomer, polymorph, solvate, or combination thereof. The prodrug can be Amprenavir phosphate. |
| FILED | Wednesday, April 29, 2020 |
| APPL NO | 16/862500 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/341 (20130101) A61K 31/497 (20130101) Original (OR) Class A61K 31/661 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/16 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364566 | Lazarus et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Nathan S. Lazarus (North Bethesda, Maryland); Gabriel L. Smith (Ellicott City, Maryland) |
| ABSTRACT | Provided, among other things, is a method of cutting and folding a planar substrate with a focused laser beam, directed from above the substrate, to form a shape with features in 3-dimensions, the method comprising: (a) executing from above laser cuts to the planar substrate so as to provide one or more a releasable segments; (b) executing from above one or more laser-executed upward folds to bend all or a portion of a releasable segment; and (c) executing from above one or more laser-executed downward folds to bend all or a portion of a releasable segment; wherein the cuts and folds are structured so that precursors to the 3D shape remain attached to the substrate while sufficient cuts and folds are made to form the 3D shape, and wherein the planar substrate is immobile during said steps (a) through (c), or is only moved in the plane of the substrate. |
| FILED | Thursday, August 09, 2018 |
| APPL NO | 16/059591 |
| ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Working or Processing of Sheet Metal or Metal Tubes, Rods or Profiles Without Essentially Removing Material; Punching Metal B21D 11/22 (20130101) B21D 11/203 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/009 (20130101) B23K 26/0093 (20130101) Original (OR) Class B23K 26/0643 (20130101) B23K 26/0648 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364658 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Yoonho Kim (Cambridge, Massachusetts); Xuanhe Zhao (Allston, Massachusetts); Hyunwoo Yuk (Cambridge, Massachusetts) |
| ABSTRACT | A responsive material having an elastomeric matrix in which ferromagnetic particles are dispersed so as to have a predetermined magnetization pattern which, when exposed to an external magnetic field, changes the shape of the responsive material from an initial shape to a predetermined transformed shape dictated by the magnetization pattern. An initial shape of the responsive material is formed by direct ink printing while applying magnetic fields to a dispensing nozzle to align the particles and gives rise to the desired magnetization pattern. |
| FILED | Wednesday, April 03, 2019 |
| APPL NO | 16/374267 |
| ART UNIT | 1748 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Preparation or Pretreatment of the Material to be Shaped; Making Granules or Preforms; Recovery of Plastics or Other Constituents of Waste Material Containing Plastics B29B 11/10 (20130101) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/10 (20200101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 7/04 (20130101) H01F 13/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364693 | Sherman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Powdermet, Inc. (Euclid, Ohio) |
| ASSIGNEE(S) | POWDERMET INC. (Euclid, Ohio) |
| INVENTOR(S) | Andrew Sherman (Mentor, Ohio); Haixong Tang (Euclid, Ohio); Brian Doud (Cleveland Heights, Ohio) |
| ABSTRACT | A composite film having a high dielectric permittivity engineered particles dispersed in a high breakdown strength polymer material to achieve high energy density. |
| FILED | Tuesday, March 03, 2020 |
| APPL NO | 16/807975 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 39/02 (20130101) B29C 39/003 (20130101) B29C 39/22 (20130101) B29C 43/24 (20130101) B29C 48/022 (20190201) B29C 49/0005 (20130101) B29C 55/04 (20130101) B29C 55/12 (20130101) B29C 55/28 (20130101) B29C 70/60 (20130101) Original (OR) Class B29C 70/882 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2105/162 (20130101) B29K 2509/02 (20130101) B29K 2995/0006 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/34 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/005 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/00 (20130101) C08K 2201/011 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/12 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 4/18 (20130101) H01G 4/32 (20130101) H01G 4/33 (20130101) H01G 4/186 (20130101) H01G 4/206 (20130101) H01G 4/306 (20130101) H01G 4/1227 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/04 (20130101) H01M 4/64 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364993 | Sumerel |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | John A. Sumerel (Chicago, Illinois) |
| ABSTRACT | An example method includes receiving pitch angle sensor information indicative of a pitch angle of a vehicle, wherein the vehicle comprises a main landing gear having a strut and a pitch control surface configured to control the pitch angle of the vehicle; determining a trailing-edge-up limit for upward movement of the pitch control surface to control a de-rotation rate of the vehicle as the vehicle lands; receiving load sensor information indicative of a load on the strut of the main landing gear of the vehicle; based on the pitch angle of the vehicle being below a pitch angle threshold, determining an updated trailing-edge-up limit based on the load on the strut; and controlling the pitch control surface based on the updated trailing-edge-up limit. |
| FILED | Wednesday, May 06, 2020 |
| APPL NO | 16/868274 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Aeroplanes; Helicopters B64C 9/00 (20130101) B64C 13/16 (20130101) Original (OR) Class B64C 25/58 (20130101) Cosmonautics; Vehicles or Equipment Therefor B64G 2700/24 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 7/003 (20130101) G01B 7/30 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 5/16 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 27/02 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0808 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11365219 | Heath et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | James R. Heath (Pasadena, California); Rosemary Dyane Rohde (Pasadena, California); Arundhati Nag (Pasadena, California); Samir Das (Pasadena, California); Aiko Umeda (Pasadena, California) |
| ABSTRACT | Peptides having activity as protein binding agents are disclosed. The peptides have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein R, R1, L1, L2, G, M, Y1Y2 and SEQ are as defined herein. Methods associated with preparation and use of such peptides, as well as pharmaceutical compositions comprising such peptides, are also disclosed. |
| FILED | Monday, June 22, 2020 |
| APPL NO | 16/908204 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0032 (20130101) A61K 49/0041 (20130101) A61K 49/0043 (20130101) A61K 51/08 (20130101) A61K 51/088 (20130101) Peptides C07K 1/047 (20130101) C07K 5/06 (20130101) C07K 5/08 (20130101) C07K 5/10 (20130101) C07K 7/56 (20130101) C07K 7/64 (20130101) Original (OR) Class C07K 14/001 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) G01N 33/6842 (20130101) G01N 2333/912 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11365220 | Pfeilsticker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Jessica A. Pfeilsticker (Pasadena, California); Aiko Umeda (Pasadena, California); James R Heath (Pasadena, California) |
| ABSTRACT | The present application provides stable peptide-based antibody capture agents and methods of use as detection and diagnosis agents. The application further provides methods of manufacturing antibody capture agents using iterative on-bead in situ click chemistry. |
| FILED | Monday, March 23, 2020 |
| APPL NO | 16/826985 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 7/08 (20130101) C07K 9/00 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56988 (20130101) G01N 2333/162 (20130101) G01N 2469/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11365243 | Diamond et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Feinstein Institutes for Medical Research (Manhasset, New York) |
| ASSIGNEE(S) | The Feinstein Institutes for Medical Research (Manhasset, New York) |
| INVENTOR(S) | Betty A. Diamond (Bronx, New York); Simone Mader (Woodside, New York); Lior Brimberg (Bayside, New York); Peter Gregersen (Larchmont, New York) |
| ABSTRACT | Methods of diagnosis and methods of treatment and prevention for autism spectrum disorder are provided using decoy antigens to maternal brain-reactive antibodies. |
| FILED | Monday, April 20, 2020 |
| APPL NO | 16/852755 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/17 (20130101) A61K 38/177 (20130101) A61K 38/1709 (20130101) A61K 38/1774 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Peptides C07K 16/18 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 33/6896 (20130101) G01N 2800/28 (20130101) G01N 2800/38 (20130101) G01N 2800/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11366039 | Kuznia et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ultra Communications, Inc. (Vista, California) |
| ASSIGNEE(S) | ULTRA COMMUNICATIONS, INC. (Vista, California) |
| INVENTOR(S) | Charles B. Kuznia (Encinitas, California); Joseph Farzin Ahadian (San Marcos, California); Sandra Skendzic (Vista, California) |
| ABSTRACT | Methods and devices for coupling light bidirectionally into optical fiber are described. The disclosed devices can be manufactured inexpensively in one-piece and integrated in high speed optical transceivers with small form-factor. The described methods and devices enable OTDR functionality in such transceivers and are compatible with sensor components mounted on a wiring or circuit board. |
| FILED | Wednesday, January 20, 2021 |
| APPL NO | 17/153432 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 11/3154 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 6/4214 (20130101) G02B 6/4246 (20130101) Transmission H04B 10/071 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11366054 | Chandrahalim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | US Govt as represented by Secretary of Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Hengky Chandrahalim (Beavercreek, Ohio); Michael Dela Cruz (Beavercreek, Ohio) |
| ABSTRACT | An optoacoustic sensor includes a liquid crystal (LC) cell formed between top and bottom plates of transparent material. A transverse grating formed across the LC cell that forms an optical transmission bandgap. A CL is aligned to form a spring-like, tunable Bragg grating that is naturally responsive to external agitations providing a spectral transition regime, or edge, in the optical transmission bandgap of the transverse grating that respond to broadband acoustic waves. The optoacoustic sensor includes a narrowband light source that is oriented to transmit light through the top plate, the LC cell, and the bottom plate. The optoacoustic sensor includes an optoacoustic spectrometer that is oriented below the bottom plate to receive the transmitted light and to record a time-domain modulation of transmission intensity at a selected one of a falling and rising edge of the transmission bandgap for detecting analog acoustic vibration. |
| FILED | Wednesday, February 05, 2020 |
| APPL NO | 16/782608 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/1702 (20130101) Original (OR) Class G01N 29/2418 (20130101) G01N 2201/0635 (20130101) G01N 2201/06113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11366066 | Koppenaal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington); Clemson University (Clemson, South Carolina); GAA Custom Engineering, LLC (Benton City, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington); Clemson University Research Foundation (Clemson, South Carolina); GAA Custom Engineering LLC (Benton City, Washington) |
| INVENTOR(S) | David W. Koppenaal (Richland, Washington); Ying Zhu (Richland, Washington); Edward D. Hoegg (Arlington, Virginia); R. Kenneth Marcus (Clemson, South Carolina); Gordon A. Anderson (Benton City, Washington); Chris Anderson (Benton City, Washington); Tyler Williams (Clemson, South Carolina) |
| ABSTRACT | Apparatus include an atmospheric pressure glow discharge (APGD) analyte electrode defining an analyte discharge axis into an APGD volume, and a plurality of APGD counter electrodes having respective electrical discharge ends directed to the APGD volume, wherein the APGD analyte electrode and the APGD counter electrodes are configured to produce an APGD plasma in the APGD volume with a voltage difference between the APGD analyte electrode and one or more of the AGPD counter electrodes. An electrode can be integrated into an ion inlet. Apparatus can be configured to perform auto-ignition and/or provide multi-modal operation through selectively powering electrodes. Electrode holder devices are disclosed. Related methods are disclosed. |
| FILED | Friday, October 11, 2019 |
| APPL NO | 16/600363 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/67 (20130101) Original (OR) Class G01N 27/62 (20130101) G01N 27/68 (20130101) G01N 30/726 (20130101) G01N 30/7233 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/32018 (20130101) H01J 37/32045 (20130101) H01J 37/32266 (20130101) H01J 47/1261 (20130101) H01J 47/1266 (20130101) H01J 49/105 (20130101) H01J 61/542 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11366100 | Roberts et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Thomas M. Roberts (Cambridge, Massachusetts); Haoxuan Tong (Cambridge, Massachusetts); Jean Zhao (Brookline, Massachusetts); John Blenis (New York, New York) |
| ABSTRACT | The present invention is based, in part, on the identification of novel FI.3K-mTORCI-S6K 1 signaling pathway biomarkers predictive of responsiveness to anti-cancer therapies. |
| FILED | Thursday, February 12, 2015 |
| APPL NO | 15/116319 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/58 (20130101) A61K 45/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) C12Q 2600/136 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) Original (OR) Class G01N 33/5088 (20130101) G01N 33/57492 (20130101) G01N 2333/91215 (20130101) G01N 2500/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11366227 | Mody et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Apurva N. Mody (Chelmsford, Massachusetts); David J. Couto (Pepperell, Massachusetts); Prabahan Basu (Lexington, Massachusetts); Michael J. Shea (Beverly, Massachusetts) |
| ABSTRACT | A multi-user system to simultaneously perform operations such as communication, RADAR, Light Detection and Ranging (LIDAR) and Relative Navigation (RELNAV). The techniques according to an embodiment includes generating a Fourier based orthogonal chirp sequence of length P, a prime number greater than the number of users targeted for communication. The orthogonal chirp sequence is based on an identifier, in the range of one to P−1, associated with one of the targeted users. The method further includes using the orthogonal chirp sequence to generate a spread user signal based on a message directed to the one targeted users. The method further includes generating a sequence of training pulses for insertion into the spread user signal to facilitate reception of the signal. The method further includes transmitting and receiving a reflection of the spread user signal from one of the targeted users, the reflection used to detect and range the user. |
| FILED | Wednesday, July 10, 2019 |
| APPL NO | 16/507832 |
| ART UNIT | 2474 — Multiplex and VoIP |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/52038 (20130101) G01S 17/26 (20200101) Original (OR) Class G01S 2205/002 (20130101) Transmission H04B 1/69 (20130101) H04B 10/5561 (20130101) H04B 2001/6912 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11366236 | Kassas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Zak M. Kassas (Irvine, California); Joshua J. Morales (Colton, California) |
| ABSTRACT | A signal of opportunity (SOP)-aided inertial navigation system (INS) framework provides various technical solutions to technical problems facing GNSS implementations. A mobile receiver, whether handheld or vehicle-mounted, has access to Global Navigation Satellite System (GNSS) signals, multiple unknown terrestrial SOPs, and IMU measurements, which are used to estimate receiver states. When GNSS signals become unreliable, the mobile receiver continues to navigate using the SOP-aided INS. The SOP-aided INS produces bounded estimation errors in the absence of GNSS signals, and the bounds are dependent on the quantity and quality of exploited SOPs. |
| FILED | Friday, September 22, 2017 |
| APPL NO | 16/335982 |
| ART UNIT | 2864 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/165 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/46 (20130101) Original (OR) Class G01S 19/47 (20130101) G01S 19/393 (20190801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11366253 | Tabirian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Beam Engineering for Advanced Measurements Co. (Orlando, Florida); U.S. Government as Represented by the Secretary of the Army (Natick, Massachusetts) |
| ASSIGNEE(S) | Beam Engineering for Advanced Measurements Co. (Orlando, Florida); U.S. Government as Represented by the Secretary of the Army (Natick, Massachusetts) |
| INVENTOR(S) | Nelson V. Tabirian (Winter Park, Florida); Svetlana Serak (Oviedo, Florida); Olena Uskova (Winter Park, Florida); David E. Roberts (Apopka, Florida); Anna Tabirian (Winter Park, Florida); Diane Steeves (Franklin, Massachusetts); Brian Kimball (Shrewsbury, Massachusetts) |
| ABSTRACT | Methods, systems and devices for diffractive waveplate lens and mirror systems allowing electronically pointing and focusing light at different focal planes. The system can be incorporated into a variety of optical schemes for providing electrical control of transmission. In another embodiment, the system comprises diffractive waveplates of different functionality to provide a system for controlling not only focusing but other propagation properties of light including direction, phase profile, and intensity distribution. The diffractive waveplate lens and mirror systems are applicable to optical communication systems. |
| FILED | Friday, January 17, 2020 |
| APPL NO | 16/746254 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/1618 (20130101) A61F 2/1654 (20130101) Optical Elements, Systems, or Apparatus G02B 3/10 (20130101) G02B 3/0081 (20130101) G02B 5/001 (20130101) G02B 5/1828 (20130101) G02B 5/1833 (20130101) Original (OR) Class G02B 5/3083 (20130101) G02B 6/024 (20130101) G02B 6/3534 (20130101) G02B 6/3592 (20130101) G02B 27/4205 (20130101) G02B 27/4211 (20130101) G02B 27/4216 (20130101) G02B 27/4261 (20130101) Spectacles; Sunglasses or Goggles Insofar as They Have the Same Features as Spectacles; Contact Lenses G02C 7/10 (20130101) G02C 7/12 (20130101) G02C 7/022 (20130101) G02C 7/061 (20130101) G02C 7/086 (20130101) G02C 2202/16 (20130101) G02C 2202/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11366296 | Devlin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts); THE CHARLES STARK DRAPER LABORATORY, INC. (Cambridge, Massachusetts) |
| INVENTOR(S) | Robert C. Devlin (Cambridge, Massachusetts); Mohammadreza Khorasaninejad (Cambridge, Massachusetts); Federico Capasso (Cambridge, Massachusetts); Hongkun Park (Cambridge, Massachusetts); Alexander Arthur High (Cambridge, Massachusetts) |
| ABSTRACT | A method of fabricating a visible spectrum optical component includes: providing a substrate; forming a resist layer over a surface of the substrate; patterning the resist layer to form a patterned resist layer defining openings exposing portions of the surface of the substrate; performing deposition to form a dielectric film over the patterned resist layer and over the exposed portions of the surface of the substrate, wherein a top surface of the dielectric film is above a top surface of the patterned resist layer; removing a top portion of the dielectric film to expose the top surface of the patterned resist layer and top surfaces of dielectric units within the openings of the patterned resist layer; and removing the patterned resist layer to retain the dielectric units over the substrate. |
| FILED | Wednesday, November 23, 2016 |
| APPL NO | 15/778208 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/042 (20130101) C23C 16/56 (20130101) C23C 16/45525 (20130101) C23C 16/45555 (20130101) Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) G02B 1/02 (20130101) G02B 1/005 (20130101) G02B 13/14 (20130101) Original (OR) Class Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0005 (20130101) G03F 7/40 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11366915 | Zhu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LEDGENDD TECHNOLOGIES INC. (Ashburn, Virginia) |
| ASSIGNEE(S) | LEDGENDD TECHNOLOGIES INC. (Ashburn, Virginia) |
| INVENTOR(S) | Wen Zhu (McLean, Virginia) |
| ABSTRACT | A method for document authorization and distribution is provided. The method is based on a system including a repository server, communicating with or hosting a repository; a blockchain network, including a plurality of peers; and a plurality of user devices, each communicating with the repository server or the blockchain network. The repository contains a plurality of published documents. A plurality of document publication records, a plurality of document dissemination records, and an access control smart contract are distributed over the peers. The method includes: when an access request for a published document is submitted by a user from a user device, retrieving the published document; verifying the document access right; encrypting the published document with a document password encrypted using the user's public key; signing and posting a document dissemination record, including the document password; and placing the document contents and a signed document hash value in a container document. |
| FILED | Tuesday, April 21, 2020 |
| APPL NO | 16/854685 |
| ART UNIT | 2494 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 16/93 (20190101) G06F 16/954 (20190101) G06F 21/602 (20130101) G06F 21/6209 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11366942 | Gupta et al. |
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| FUNDED BY |
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| APPLICANT(S) | Siemens Corporation (Iselin, New Jersey); Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Siemens Corporation (Iselin, New Jersey); Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Ashish Gupta (Atlanta, Georgia); George Allen (Okinawa, Japan); Jaroslaw Rossignac (Atlanta, Georgia); Suraj Ravi Musuvathy (Princeton Junction, New Jersey); Livio Dalloro (Plainsboro, New Jersey) |
| ABSTRACT | A computer-implemented method for constructing structures using beams bounded by quadric surfaces of revolution includes generating a quador beam within a computer-aided design (CAD) tool. The quador beam comprises two spheres at opposing endpoints, and the beam is bounded by a quadric surface of revolution around an axis of symmetry joining the center of the two spheres. The quadric surface of revolution abuts with tangent continuity with the surface of each of the spheres. Once generated, the quador beam can be visualized in the CAD tool or another display medium. |
| FILED | Tuesday, September 04, 2018 |
| APPL NO | 16/641305 |
| ART UNIT | 2148 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 30/17 (20200101) Original (OR) Class G06F 2111/20 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11367189 | Clymer et al. |
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| FUNDED BY |
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| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Daniel Clymer (Pittsburgh, Pennsylvania); Jonathan Cagan (Pittsburgh, Pennsylvania); Philip LeDuc (Pittsburgh, Pennsylvania) |
| ABSTRACT | A hierarchical deep-learning object detection framework provides a method for identifying objects of interest in high-resolution, high pixel count images, wherein the objects of interest comprise a relatively a small pixel count when compared to the overall image. The method uses first deep-learning model to analyze the high pixel count images, in whole or as a patchwork, at a lower resolution to identify objects, and a second deep-learning model to analyze the objects at a higher resolution to classify the objects. |
| FILED | Friday, October 16, 2020 |
| APPL NO | 17/073041 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6247 (20130101) G06K 9/6257 (20130101) G06K 9/6268 (20130101) G06K 9/6277 (20130101) G06K 9/6298 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 2207/10056 (20130101) G06T 2207/20021 (20130101) G06T 2207/20081 (20130101) G06T 2207/30101 (20130101) Image or Video Recognition or Understanding G06V 20/695 (20220101) G06V 20/698 (20220101) G06V 2201/031 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11367539 | Zheng et al. |
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| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | Board of Trustees, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Yuebing Zheng (Austin, Texas); Jingang Li (Austin, Texas) |
| ABSTRACT | Disclosed herein are methods of manipulating particles on solid substrates via optothermally-gated photon nudging. |
| FILED | Tuesday, November 24, 2020 |
| APPL NO | 17/103240 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11367800 | Welser et al. |
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| FUNDED BY |
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| APPLICANT(S) | Magnolia Solar, Inc. (Woburn, Massachusetts) |
| ASSIGNEE(S) | Magnolia Solar, Inc. (Woburn, Massachusetts) |
| INVENTOR(S) | Roger E. Welser (Providence, Rhode Island); Ashok K. Sood (Brookline, Massachusetts) |
| ABSTRACT | Optically-thin, quantum-structured solar cells incorporating III-V quantum wells or quantum dots have the potential to revolutionize the performance of photovoltaic devices. Enhanced spectral response characteristics have been widely demonstrated in both quantum well and quantum dot solar cells using a variety of different III-V materials. To fully leverage the extended spectral response of quantum-structured solar cells, new device designs are disclosed that can both maximize the current generating capability of the limited volume of narrow band gap material and minimize the unwanted carrier recombination that degrades the voltage output. |
| FILED | Monday, February 26, 2018 |
| APPL NO | 15/905698 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/03046 (20130101) H01L 31/035218 (20130101) H01L 31/035281 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11367948 | Jordan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cubic Corporation (San Diego, California) |
| ASSIGNEE(S) | CUBIC CORPORATION (, None) |
| INVENTOR(S) | Jared Williams Jordan (Raleigh, North Carolina); Timothy Amis Smith (Durham, North Carolina); Freddy Pinero (Durham, North Carolina); Brian Michael Kerrigan (Cary, North Carolina) |
| ABSTRACT | Antenna integrated into a compact conical nosecone. |
| FILED | Wednesday, August 19, 2020 |
| APPL NO | 16/997176 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/28 (20130101) Original (OR) Class H01Q 1/281 (20130101) H01Q 1/422 (20130101) H01Q 11/105 (20130101) H01Q 13/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11368024 | Yeh |
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| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Hen-Geul Yeh (Cypress, California) |
| ABSTRACT | Centralized controllers for a photovoltaic-enabled distribution grid are described herein. Photovoltaic cells may generate electricity that may be supplied to the distribution grid, which may experience unexpected abnormal power loads. The controllers utilize photovoltaic inverters connected to the photovoltaic cells to optimize the performance of the grid by absorbing or injecting reactive power. These controllers are particularly efficient in handling unexpected abnormal power loads. |
| FILED | Wednesday, August 19, 2020 |
| APPL NO | 16/996968 |
| ART UNIT | 2115 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/042 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/381 (20130101) Original (OR) Class H02J 2203/20 (20200101) H02J 2300/24 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11368214 | Ahadian et al. |
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| FUNDED BY |
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| APPLICANT(S) | ULTRA COMMUNICATIONS, INC. (Vista, California) |
| ASSIGNEE(S) | ULTRA COMMUNICATIONS, INC. (Vista, California) |
| INVENTOR(S) | Joseph F. Ahadian (San Marcos, California); Vahid Nazer (San Marcos, California); Sandra Skendzic (Vista, California); Charles B. Kuznia (Encinitas, California); Richard J. Weiss (San Diego, California) |
| ABSTRACT | Methods and systems for automated health assessment of fiber optic links of a fiber optic communication system are described. Tables are used to describe the fiber optic links, including access addresses to communication modules used in the links. Telemetry data representative of operation of the communication modules can be read via the access addresses into a central station. OTDR/OFDR measurement data of fiber optic segments used in the links can be read via the access addresses into the central station. The telemetry and/or OTDR/OFDR measurement data can be used by the central station for comparison against reference data to assess health of the links. The communication modules locally and continuously capture the telemetry data to detect transient events that may be the result of tampering of the links. |
| FILED | Monday, May 17, 2021 |
| APPL NO | 17/322743 |
| ART UNIT | 2637 — Optical Communications |
| CURRENT CPC | Transmission H04B 10/071 (20130101) Original (OR) Class H04B 10/0793 (20130101) H04B 10/07955 (20130101) H04B 10/07957 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11368225 | Koste |
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| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Niskayuna, New York) |
| INVENTOR(S) | Glen Peter Koste (Schenectady, New York) |
| ABSTRACT | A satellite relay communication system includes a central terminal. The central terminal includes a passive optical router and a multiplexer. The satellite relay communication system also includes remote terminals, each remote terminal including an optical transceiver configured to send optical signals to the passive optical router, configured to receive optical signals from the passive optical router, and configured to multiplex optical signals received from the passive optical router. |
| FILED | Tuesday, March 17, 2020 |
| APPL NO | 16/821546 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Transmission H04B 10/11 (20130101) H04B 10/29 (20130101) Original (OR) Class H04B 10/40 (20130101) Multiplex Communication H04J 14/02 (20130101) H04J 14/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11368318 | Cunningham et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Robert Cunningham (Lexington, Massachusetts); Richard Shay (Norwood, Massachusetts) |
| ABSTRACT | A method for identifying a group of users from a number of users includes receiving, for each user of the number of users, response data including motion data characterizing motion of the user during a prescribed time period occurring after issuance of a challenge to the number of users, processing the motion data of the number of users to identify a first subset of the number of users with substantially matching motion data, and forming the group of users to include the first subset of the number of users. |
| FILED | Tuesday, July 31, 2018 |
| APPL NO | 16/050114 |
| ART UNIT | 2433 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0866 (20130101) H04L 9/3231 (20130101) H04L 9/3271 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11368470 | Liu et al. |
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| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Yushan Liu (Princeton, New Jersey); Xiaokui Shu (Ossining, New York); Douglas Lee Schales (Ardsley, New York); Marc Philippe Stoecklin (White Plains, New York) |
| ABSTRACT | Advanced Persistent Threat (APT) defense leverages priority-based tracking around alerts, together with priority-based alert reasoning task scheduling. In one embodiment, individual alert reasoning tasks are managed by an alert scheduler, which effectively allocates available computation resources to prioritize the alert reasoning tasks, which each execute within processing workers that are controlled by the alert scheduler. An alert reasoning task typically is prioritized (relative to other such tasks) according to one or more factors, such as severity levels, elapsed time, and other tracking results. By implementing priority-based task scheduling, the task scheduler provides for alert reasoning tasks that are interruptible. In this approach, and once an alert is assigned to a task and the task assigned a worker, priority-based connectivity tracker around each alert is carried out to provide further computational efficiency. |
| FILED | Thursday, June 13, 2019 |
| APPL NO | 16/439916 |
| ART UNIT | 2496 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1416 (20130101) Original (OR) Class H04L 63/1441 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11364398 | Brown |
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| FUNDED BY |
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| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Erik P. Brown (Tracy, California) |
| ABSTRACT | A combination seal connects a filter or an equipment component to a base. The combination seal includes a seal material and flecks or particles made of intumescent material interspersed within the seal material. The flecks or particles of intumescent material undergo a chemical change when exposed to flames or heat and expand to maintain seal effectiveness and longevity without compromise. |
| FILED | Thursday, August 03, 2017 |
| APPL NO | 15/667886 |
| ART UNIT | 3675 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Fire-fighting A62C 2/065 (20130101) Original (OR) Class Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/185 (20130101) Pistons; Cylinders; Sealings F16J 15/00 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 5/04 (20130101) F16L 21/005 (20130101) F16L 57/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364471 | Ho et al. |
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| FUNDED BY |
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| APPLICANT(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
| ASSIGNEE(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
| INVENTOR(S) | W. S. Winston Ho (Columbus, Ohio); Prabir Dutta (Worthington, Ohio); Kartik Ramasubramanian (Waynesboro, Virginia); Michael Severance (Columbus, Ohio) |
| ABSTRACT | Membranes, methods of making the membranes, and methods of using the membranes are described herein. The membranes can comprise a gas permeable support layer, an inorganic layer disposed on the support, the inorganic layer comprising a plurality of discreet nanoparticles having an average particle size of less than 1 micron, and a selective polymer layer disposed on the inorganic layer, the selective polymer layer comprising a selective polymer having a CO2:N2 selectivity of at least 10 at 57° C. In some embodiments, the membrane can be selectively permeable to an acidic gas. The membranes can be used, for example, to separate gaseous mixtures, such as flue gas. |
| FILED | Monday, June 17, 2019 |
| APPL NO | 16/443182 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/228 (20130101) B01D 67/0079 (20130101) B01D 67/0088 (20130101) B01D 69/12 (20130101) B01D 69/148 (20130101) Original (OR) Class B01D 71/028 (20130101) B01D 71/60 (20130101) B01D 71/68 (20130101) B01D 2257/80 (20130101) B01D 2257/302 (20130101) B01D 2257/304 (20130101) B01D 2257/404 (20130101) B01D 2257/504 (20130101) B01D 2257/2045 (20130101) B01D 2258/05 (20130101) B01D 2258/0283 (20130101) B01D 2323/30 (20130101) B01D 2325/20 (20130101) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 20/40 (20200801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364527 | Takata et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Keystone Tower Systems, Inc. (Denver, Colorado) |
| ASSIGNEE(S) | Keystone Tower Systems, Inc. (Denver, Colorado) |
| INVENTOR(S) | Rosalind K. Takata (Denver, Colorado); Eric D. Smith (Denver, Colorado); Loren Daniel Bridgers (Golden, Colorado); Daniel Ainge (Boulder, Colorado); Alexander H. Slocum (Bow, New Hampshire) |
| ABSTRACT | A control system for forming a tapered structure includes a sensor providing feedback for a machine for forming a tapered structure including at least three rolls having at least one bend roll and at least two guide rolls. The guide rolls may include rollette banks having a plurality of rollettes. The machine may also include an adjustment mechanism to position at least one of the rolls, where a diameter of the tapered structure being formed is controlled by relative positions of the rolls. The machine may also include a joining element to join edges of a stock of material together as it is rolled through the rolls to form the tapered structure. The control system may also include a controller to receive feedback from the sensor and to send a control signal based on the feedback to the adjustment mechanism for positioning at least one of the rolls. |
| FILED | Tuesday, December 04, 2018 |
| APPL NO | 16/208831 |
| ART UNIT | 3799 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Manufacture of Metal Sheets, Wire, Rods, Tubes or Profiles, Otherwise Than by Rolling; Auxiliary Operations Used in Connection With Metal-working Without Essentially Removing Material B21C 37/122 (20130101) B21C 37/124 (20130101) B21C 37/126 (20130101) B21C 37/128 (20130101) B21C 37/185 (20130101) Original (OR) Class Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 9/0325 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364654 | Cramer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Corson L. Cramer (Knoxville, Tennessee); Richard A. Lowden (Clinton, Tennessee); Kinga A. Unocic (Knoxville, Tennessee); Jacob W. McMurray (Clinton, Tennessee); Amelia M. Elliott (Knoxville, Tennessee) |
| ABSTRACT | A method for indirect additive manufacturing of an object constructed of boron carbide, silicon carbide, and free silicon, comprising: (i) producing a porous preform constructed of boron carbide and silicon carbide by an indirect ceramic additive manufacturing (ICAM) process in which particles of a powder mixture become bonded together with an organic binder, wherein the powder mixture comprises: a) boron carbide particles, and b) silicon carbide particles, wherein at least 80 vol % of the silicon carbide particles are larger than the boron carbide particles; and wherein the boron carbide and silicon carbide particles are each included in an amount of 40-60 wt. % of the powder mixture, provided that the foregoing amounts sum to at least 95 wt. %; (ii) subjecting the porous preform to a temperature of 500-900° C. to volatilize the organic binder; and (iii) infiltrating molten silicon into pores of the porous preform to produce the object. |
| FILED | Tuesday, December 17, 2019 |
| APPL NO | 16/717356 |
| ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 1/001 (20130101) Original (OR) Class B28B 17/0063 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/563 (20130101) C04B 35/565 (20130101) C04B 35/632 (20130101) C04B 38/06 (20130101) C04B 38/0041 (20130101) C04B 2235/386 (20130101) C04B 2235/428 (20130101) C04B 2235/3821 (20130101) C04B 2235/3826 (20130101) C04B 2235/5427 (20130101) C04B 2235/5436 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11365133 | Cao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ADVANCED COOLING TECHNOLOGIES, INC. (Lancaster, Pennsylvania) |
| ASSIGNEE(S) | ADVANCED COOLING TECHNOLOGIES, INC. (Lancaster, Pennsylvania) |
| INVENTOR(S) | Fangyu Cao (Alexandria, Virginia); Jianjian Wang (Lancaster, Pennsylvania); Howard Pearlman (Haddon Township, New Jersey) |
| ABSTRACT | A method of purifying brackish water includes mixing brackish water with a nucleating agent, forming nucleated liquid water and distributing droplets of the nucleated liquid water inside a vacuum chamber, vacuum freezing the droplets of the nucleated liquid water in the vacuum chamber. The method further includes the droplets forming pure water vapor, nucleated ice, and remaining brackish water, mixing and liquifying the pure water vapor and the nucleated ice, forming a mixture of purified liquid water and the nucleating agent. The method further includes separating the mixture of purified liquid water and the nucleating agent, forming purified liquid water and the nucleating agent. |
| FILED | Wednesday, May 01, 2019 |
| APPL NO | 16/400522 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/22 (20130101) Original (OR) Class C02F 1/265 (20130101) C02F 2103/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11365294 | Ren et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| INVENTOR(S) | Zhifeng Ren (Pearland, Texas); Dan Luo (Houston, Texas); Feng Wang (Houston, Texas) |
| ABSTRACT | A facile and scalable method to prepare graphene-based amphiphilic Janus nanosheets with high efficiency utilizing the formation of hydrogen bonding to immobilize graphene oxide (GO) on the surfaces of starch microspheres. After selective functionalization of the exposed surface using alkylamine, amphiphilic Janus nanosheets (AJN) were obtained by releasing the nanosheets from the starch microspheres. |
| FILED | Friday, July 27, 2018 |
| APPL NO | 16/636628 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/198 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/24 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/215 (20130101) Original (OR) Class C08J 2303/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11365410 | Rogers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Jameson K. Rogers (Boston, Massachusetts); George M. Church (Brookline, Massachusetts) |
| ABSTRACT | Methods of making and monitoring metabolites in cells are provided. |
| FILED | Tuesday, April 12, 2016 |
| APPL NO | 15/566040 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/10 (20130101) C12N 15/1086 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11365431 | D'Espaux et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Leopold D'Espaux (San Francisco, California); Jay D. Keasling (Berkeley, California) |
| ABSTRACT | The present invention provides for a genetically modified yeast cell comprising at least six or more of the following modifications: increased expression of Mus musculus fatty acid reductase, acetyl-CoA carboxylase, fatty acid synthase 1, fatty acid synthase 2, a mutant of the bottleneck enzyme encoded by ACC1 insensitive to post-transcriptional and post-translational repression, and/or a desaturase encoded by OLE1, and reduced expression of DGA1, HFD1, ADH6, and/or GDH1. The present invention provides a method for constructing the genetically modified yeast cell, and a method for producing a fatty alcohol from the genetically modified yeast cell. |
| FILED | Monday, February 10, 2020 |
| APPL NO | 16/786558 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0008 (20130101) C12N 9/93 (20130101) C12N 9/1029 (20130101) C12N 15/52 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/04 (20130101) Original (OR) Class Enzymes C12Y 101/01001 (20130101) C12Y 102/01084 (20150701) C12Y 203/0102 (20130101) C12Y 203/01085 (20130101) C12Y 604/01002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11365463 | Rios et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Orlando Rios (Oak Ridge, Tennessee); Hunter B. Henderson (Knoxville, Tennessee); Michael S. Kesler (Oak Ridge, Tennessee); Bruce A. Moyer (Oak Ridge, Tennessee); Zachary Sims (Knoxville, Tennessee); David Weiss (Manitowoc, Wisconsin); Ryan Ott (Ames, Iowa); Corby Anderson (Golden, Colorado); Hao Cui (Golden, Colorado); Scott McCall (Livermore, California) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); University of Tennessee Research Foundation (Knoxville, Tennessee); Eck Industries Incorporated (Manitowoc, Wisconsin); Iowa State University Research Foundation, Inc. (Ames, Iowa); Colorado School of Mines (Golden, Colorado); Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Orlando Rios (Oak Ridge, Tennessee); Hunter B. Henderson (Knoxville, Tennessee); Michael S. Kesler (Oak Ridge, Tennessee); Bruce A. Moyer (Oak Ridge, Tennessee); Zachary Sims (Knoxville, Tennessee); David Weiss (Manitowoc, Wisconsin); Ryan Ott (Ames, Iowa); Corby Anderson (Golden, Colorado); Hao Cui (Golden, Colorado); Scott McCall (Livermore, California) |
| ABSTRACT | The disclosure concerns methods for making a composition comprising a light metal and an intermetallic comprising the light metal and a light rare earth element. The composition also may include a plurality of nanoparticles comprising an oxide of the light metal. The method includes directly reducing a light rare earth element precursor compound in a melt of the light metal, thereby forming the light rare earth element and nanoparticles of the light metal oxide. |
| FILED | Tuesday, February 04, 2020 |
| APPL NO | 16/781635 |
| ART UNIT | 1738 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Alloys C22C 1/026 (20130101) C22C 1/0416 (20130101) C22C 1/0491 (20130101) C22C 21/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11365485 | Bahar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Xergy Inc. (Harrington, Delaware) |
| ASSIGNEE(S) | FFI Ionix IP, Inc. (Wilmington, Delaware) |
| INVENTOR(S) | Bamdad Bahar (Georgetown, Delaware); Jacob Zerby (Harbeson, Delaware) |
| ABSTRACT | An ozone generator system utilizes an electrochemical cell to produce and control ozone concentrations within an enclosure or to supply ozone to a flow conduit. The enclosure may he coupled with a flow conduit that carries the produced ozone to a desired location. An enclosure may be a sterilization chamber and the concentration of ozone produced by the ozone generating system may be sufficient to sterilize articles within the enclosure. An oxygen control electrolyzer cell and/or humidity control electrolyzer cell may be coupled with the enclosure to further control the environment of the enclosure. A humidity control electrolyzer cell may be fluidly coupled with the ozone generator to supply humidity for reaction on the anode of the ozone generator. |
| FILED | Friday, September 08, 2017 |
| APPL NO | 15/698842 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/13 (20130101) C25B 9/23 (20210101) C25B 9/70 (20210101) C25B 15/02 (20130101) Original (OR) Class C25B 15/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11366066 | Koppenaal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington); Clemson University (Clemson, South Carolina); GAA Custom Engineering, LLC (Benton City, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington); Clemson University Research Foundation (Clemson, South Carolina); GAA Custom Engineering LLC (Benton City, Washington) |
| INVENTOR(S) | David W. Koppenaal (Richland, Washington); Ying Zhu (Richland, Washington); Edward D. Hoegg (Arlington, Virginia); R. Kenneth Marcus (Clemson, South Carolina); Gordon A. Anderson (Benton City, Washington); Chris Anderson (Benton City, Washington); Tyler Williams (Clemson, South Carolina) |
| ABSTRACT | Apparatus include an atmospheric pressure glow discharge (APGD) analyte electrode defining an analyte discharge axis into an APGD volume, and a plurality of APGD counter electrodes having respective electrical discharge ends directed to the APGD volume, wherein the APGD analyte electrode and the APGD counter electrodes are configured to produce an APGD plasma in the APGD volume with a voltage difference between the APGD analyte electrode and one or more of the AGPD counter electrodes. An electrode can be integrated into an ion inlet. Apparatus can be configured to perform auto-ignition and/or provide multi-modal operation through selectively powering electrodes. Electrode holder devices are disclosed. Related methods are disclosed. |
| FILED | Friday, October 11, 2019 |
| APPL NO | 16/600363 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/67 (20130101) Original (OR) Class G01N 27/62 (20130101) G01N 27/68 (20130101) G01N 30/726 (20130101) G01N 30/7233 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/32018 (20130101) H01J 37/32045 (20130101) H01J 37/32266 (20130101) H01J 47/1261 (20130101) H01J 47/1266 (20130101) H01J 49/105 (20130101) H01J 61/542 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11366116 | Meagher et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Robert Meagher (Mountain House, California); Ronald F. Renzi (Rexford, New York); Cameron Scott Ball (Los Altos, California); Aashish Priye (Livermore, California); Jonathan Ivers Helm (Oakland, California); Bryan Carson (Tijeras, New Mexico); Stanley Alan Langevin (Seattle, Washington) |
| ABSTRACT | The present invention relates, in part, to systems configured to obtain samples from an organism in an autonomous manner. Such systems can employ a cartridge configured to provide bait to attract an organism, as well as channels to store and/or test samples obtained from the organism. |
| FILED | Thursday, April 12, 2018 |
| APPL NO | 15/951920 |
| ART UNIT | 1799 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/548 (20130101) G01N 33/5304 (20130101) G01N 33/56983 (20130101) Original (OR) Class G01N 2469/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11366122 | Ha et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Noel Ha (El Cerrito, California); Markus de Raad (Berkeley, California); Trent R. Northen (Walnut Creek, California) |
| ABSTRACT | Disclosed herein include systems, devices, and methods for droplet deposition for mass spectrometry. In some embodiments, a microfluidic device comprising wells is reversibly sealed to a mass spectrometry surface and used to deposit contents of droplets (e.g., enzymes and substrates), or products thereof, onto the mass spectrometry surface. The contents of droplets can be analyzed by laser desorption/ionization to, for example, identify a substrate of an enzyme or an enzyme capable of catalyzing a substrate to a product. |
| FILED | Sunday, October 04, 2020 |
| APPL NO | 17/062609 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6851 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 49/0004 (20130101) H01J 49/0418 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11366401 | Sampayan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California); Opcondys, inc. (Manteca, California) |
| ASSIGNEE(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California); OPCONDYS, INC. (Manteca, California) |
| INVENTOR(S) | Stephen Sampayan (Livermore, California); Paulius Vytautas Grivickas (Pleasanton, California); Kristin Cortella Sampayan (Manteca, California) |
| ABSTRACT | Techniques, systems, and devices are disclosed for implementing a photoconductive device performing bulk conduction. In one exemplary aspect, a photoconductive device is disclosed. The device includes a light source configured to emit light; a crystalline material positioned to receive the light from the light source, wherein the crystalline material is doped with a dopant that forms a mid-gap state within a bandgap of the crystalline material to control a recombination time of the crystalline material; a first electrode coupled to the crystalline material to provide a first electrical contact for the crystalline material, and a second electrode coupled to the crystalline material to provide a second electrical contact for the crystalline material, wherein the first and the second electrodes are configured to establish an electric field across the crystalline material, and the crystalline material is configured to exhibit a substantially linear transconductance in response to receiving the light. |
| FILED | Friday, September 22, 2017 |
| APPL NO | 16/630273 |
| ART UNIT | 2896 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/4295 (20130101) Electrography; Electrophotography; Magnetography G03G 5/04 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/09 (20130101) H01L 31/101 (20130101) H01L 31/173 (20130101) Pulse Technique H03K 17/78 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11367551 | Snow et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Montana State University (Bozeman, Montana); The Regents of The University of California (Oakland, California) |
| ASSIGNEE(S) | Montana State University (Bozeman, Montana); The Regents of The University of California (Oakland, California) |
| INVENTOR(S) | Ryan J. Snow (Bozeman, Montana); Yves U. Idzerda (Bozeman, Montana); Elke Arenholz (Berkeley, California) |
| ABSTRACT | Large magnetic moment compositions are formed by stabilizing ternary or other alloys with a epitaxial control layer. Compositions that are unstable in bulk specimen are thus stabilized and exhibit magnetic moments that are greater that a Slater-Pauling limit. In one example, FexCoyMnz layers are produced on an MgO(001) substrate with an MgO surface serving to control the structure of the FexCoyMnz layers. Magnetizations greater than 3 Bohr magnetons are produced. |
| FILED | Friday, December 14, 2018 |
| APPL NO | 16/954983 |
| ART UNIT | 1785 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/09 (20130101) G01R 33/0052 (20130101) Information Storage Based on Relative Movement Between Record Carrier and Transducer G11B 5/82 (20130101) G11B 5/656 (20130101) G11B 5/7368 (20190501) G11B 5/7377 (20190501) G11B 5/7379 (20190501) Static Stores G11C 11/14 (20130101) G11C 11/161 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 10/16 (20130101) H01F 10/30 (20130101) H01F 10/147 (20130101) Original (OR) Class H01F 41/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11367802 | Steiner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); Georgia Institute of Technology (Atlanta, Georgia) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Myles Aaron Steiner (Denver, Colorado); Daniel Joseph Friedman (Lakewood, Colorado); Ryan Matthew France (Golden, Colorado); Asegun Henry (Boston, Massachusetts) |
| ABSTRACT | The present disclosure relates to a photovoltaic (PV) device that includes a first junction constructed with a first alloy and having a bandgap between about 1.0 eV and about 1.5 eV, and a second junction constructed with a second alloy and having a bandgap between about 0.9 eV and about 1.3 eV, where the first alloy includes III-V elements, the second alloy includes III-V elements, and the PV device is configured to operate in a thermophotovoltaic system having an operating temperature between about 1500° C. and about 3000° C. |
| FILED | Thursday, February 07, 2019 |
| APPL NO | 16/269848 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0725 (20130101) H01L 31/0735 (20130101) Original (OR) Class H01L 31/1892 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 10/30 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11367870 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Wei Chen (Stanford, California); Yi Cui (Stanford, California) |
| ABSTRACT | A rechargeable manganese battery includes: (1) a first electrode including a porous, conductive support; (2) a second electrode including a catalyst support and a catalyst disposed over the catalyst support; and (3) an electrolyte disposed between the first electrode and the second electrode to support reversible precipitation and dissolution of manganese at the first electrode and reversible evolution and oxidation of hydrogen at the second electrode. |
| FILED | Tuesday, May 29, 2018 |
| APPL NO | 16/611253 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/50 (20130101) Original (OR) Class H01M 4/663 (20130101) H01M 4/926 (20130101) H01M 2300/0005 (20130101) H01M 2300/0017 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11363994 | Reich et al. |
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| FUNDED BY |
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| APPLICANT(S) | Alton Reich (Huntsville, Alabama); Rodrigo E. Teixeira (Madison, Alabama) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alton Reich (Huntsville, Alabama); Rodrigo E. Teixeira (Madison, Alabama) |
| ABSTRACT | The invention comprises a method and apparatus for estimating state of a cardiovascular system, comprising a cardiac stroke volume analyzer, comprising: (1) a blood pressure sensor generating a time-varying pressure state waveform output from a limb of the person; (2) a system processor connected to the blood pressure sensor; and (3) a dynamic state-space model; the system processor receiving cardiovascular input data, from the blood pressure sensor, related to a transient pressure state of the cardiovascular system; at least one probabilistic model, of the dynamic state-space model, operating on the time-varying pressure state waveform output to generate a probability distribution function to a non-pressure state of the cardiovascular system; iteratively updating the probability distribution function using output from the blood pressure sensor; and processing the probability distribution function to generate a non-pressure state output related to stroke volume of a heart of the person and arterial compliance of the person. |
| FILED | Tuesday, August 06, 2019 |
| APPL NO | 16/533778 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/029 (20130101) A61B 5/742 (20130101) A61B 5/02007 (20130101) A61B 5/02108 (20130101) A61B 5/02233 (20130101) A61B 5/02255 (20130101) A61B 5/7275 (20130101) Original (OR) Class A61B 2560/0223 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364105 | Schwartz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Jeffrey Schwartz (Princeton, New Jersey); Jean E. Schwarzbauer (Princeton, New Jersey); Casey M. Jones (Portland, Oregon); Patrick E. Donnelly (Lawrenceville, New Jersey); Stephen B. Bandini (Newton, Massachusetts); Shivani Singh (Princeton, New Jersey) |
| ABSTRACT | The present invention provides tissue scaffolds, methods of generating such scaffolds, and methods of use of such scaffolds to generate aligned and functional neural tissues for use in methods including regenerative medicine, wound repair and transplantation. |
| FILED | Wednesday, October 05, 2016 |
| APPL NO | 15/767616 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/0077 (20130101) Original (OR) Class A61F 2002/0086 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/02 (20130101) A61L 27/06 (20130101) A61L 27/10 (20130101) A61L 27/16 (20130101) A61L 27/24 (20130101) A61L 27/047 (20130101) A61L 27/227 (20130101) A61L 27/306 (20130101) A61L 27/383 (20130101) A61L 27/3633 (20130101) A61L 27/3834 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) C12N 2533/10 (20130101) C12N 2533/12 (20130101) C12N 2533/30 (20130101) C12N 2533/90 (20130101) C12N 2535/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
11364139 — Variable stiffness devices that use the principles of granular jamming and methods of use
| US 11364139 | Chang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Young-Hui Chang (Atlanta, Georgia); I-Ting Chuang (Atlanta, Georgia); Geza Frank Kogler (Atlanta, Georgia); Emily Simonds (Atlanta, Georgia) |
| ABSTRACT | Embodiments of the present disclosure relate generally to variable stiffness devices, including orthoses, that use the principles of granular jamming. In some embodiments, a device may comprise a cell having an air impermeable outer bladder. The outer bladder of the cell can define an internal pocket. A plurality of granular particulates may be disposed within the first cell. The stiffness of the cell can be altered by altering the negative internal pressure of the cell, thereby causing the granular particulates to compact, or jam. In some embodiments, a plurality of cells may be disposed within a device. The location of each of the plurality of cells may correspond to a location of a user's foot. The mechanical characteristics of each cell of the plurality of cells may be independently adjusted by adjusting the negative internal pressure of the cell. |
| FILED | Monday, March 11, 2019 |
| APPL NO | 16/298214 |
| ART UNIT | 3786 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 5/14 (20130101) A61F 5/32 (20130101) Original (OR) Class A61F 5/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
11364197 — Compositions and methods of making brittle-matrix particles through blister pack freezing
| US 11364197 | Johnston et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Keith P. Johnston (Austin, Texas); Joshua Engstrom (Spotswood, New Jersey); Jasmine Rowe (Austin, Texas); Alan B. Watts (Plainsboro, New Jersey); Robert O. Williams, III (Austin, Texas) |
| ABSTRACT | The present invention includes compositions and methods for treating and delivering medicinal formulations using an inhaler. The composition includes a space filled flocculated suspension having one or more flocculated particles of one or more active agents and a hydrofluoroalkane propellant. A portion of the one or more flocculated particles is templated by the formation of hydrofluoroalkane droplets upon atomization and the templated floc compacts upon the evaporation of the hydrofluoroalkane propellant to form a porous particle for deep lung delivery. |
| FILED | Friday, April 03, 2020 |
| APPL NO | 16/839957 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/008 (20130101) Original (OR) Class A61K 9/0075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364527 | Takata et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Keystone Tower Systems, Inc. (Denver, Colorado) |
| ASSIGNEE(S) | Keystone Tower Systems, Inc. (Denver, Colorado) |
| INVENTOR(S) | Rosalind K. Takata (Denver, Colorado); Eric D. Smith (Denver, Colorado); Loren Daniel Bridgers (Golden, Colorado); Daniel Ainge (Boulder, Colorado); Alexander H. Slocum (Bow, New Hampshire) |
| ABSTRACT | A control system for forming a tapered structure includes a sensor providing feedback for a machine for forming a tapered structure including at least three rolls having at least one bend roll and at least two guide rolls. The guide rolls may include rollette banks having a plurality of rollettes. The machine may also include an adjustment mechanism to position at least one of the rolls, where a diameter of the tapered structure being formed is controlled by relative positions of the rolls. The machine may also include a joining element to join edges of a stock of material together as it is rolled through the rolls to form the tapered structure. The control system may also include a controller to receive feedback from the sensor and to send a control signal based on the feedback to the adjustment mechanism for positioning at least one of the rolls. |
| FILED | Tuesday, December 04, 2018 |
| APPL NO | 16/208831 |
| ART UNIT | 3799 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Manufacture of Metal Sheets, Wire, Rods, Tubes or Profiles, Otherwise Than by Rolling; Auxiliary Operations Used in Connection With Metal-working Without Essentially Removing Material B21C 37/122 (20130101) B21C 37/124 (20130101) B21C 37/126 (20130101) B21C 37/128 (20130101) B21C 37/185 (20130101) Original (OR) Class Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 9/0325 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364658 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Yoonho Kim (Cambridge, Massachusetts); Xuanhe Zhao (Allston, Massachusetts); Hyunwoo Yuk (Cambridge, Massachusetts) |
| ABSTRACT | A responsive material having an elastomeric matrix in which ferromagnetic particles are dispersed so as to have a predetermined magnetization pattern which, when exposed to an external magnetic field, changes the shape of the responsive material from an initial shape to a predetermined transformed shape dictated by the magnetization pattern. An initial shape of the responsive material is formed by direct ink printing while applying magnetic fields to a dispensing nozzle to align the particles and gives rise to the desired magnetization pattern. |
| FILED | Wednesday, April 03, 2019 |
| APPL NO | 16/374267 |
| ART UNIT | 1748 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Preparation or Pretreatment of the Material to be Shaped; Making Granules or Preforms; Recovery of Plastics or Other Constituents of Waste Material Containing Plastics B29B 11/10 (20130101) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/10 (20200101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 7/04 (20130101) H01F 13/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11365225 | Joshi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Neel Satish Joshi (Somerville, Massachusetts); Peter Quoc Nguyen (Malden, Massachusetts) |
| ABSTRACT | Methods of making recombinant secretion of silk and silk-amyloid proteins using bacteria are provided. |
| FILED | Friday, November 18, 2016 |
| APPL NO | 15/776998 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/47 (20130101) C07K 14/78 (20130101) C07K 14/43518 (20130101) Original (OR) Class C07K 2319/10 (20130101) C07K 2319/036 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/205 (20210501) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/19 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11365297 | Rangari et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TUSKEGEE UNIVERSITY (Tuskegee, Alabama) |
| ASSIGNEE(S) | TUSKEGEE UNIVERSITY (Tuskegee, Alabama) |
| INVENTOR(S) | Vijaya K Rangari (Tuskegee, Alabama); Samia Islam (Tuskegee, Alabama); Woubit Salah Abebe (Tuskegee, Alabama) |
| ABSTRACT | A biopolymer film is provided that comprises a combination of: crystalline nano cellulose (CNC)/esterified crystalline nano cellulose (ECNC) reinforced with chitosan. The two polymer components can be present in any ratio but an approximate CNC to ECNC 70:30 ratio is preferred. The chitosan component is derived from exoskeletons of crustaceans. Also provided are methods of preparing biopolymer film and preparing food packaging components from said biopolymer film. The CNC/ECNC mixture is dissolved in an ethanol solution and the chitin is dissolved in acetic acid and mixed together to form a polymer blend. |
| FILED | Thursday, January 03, 2019 |
| APPL NO | 16/239109 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Polysaccharides; Derivatives Thereof C08B 3/12 (20130101) C08B 15/005 (20130101) C08B 37/003 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/18 (20130101) Original (OR) Class C08J 2301/02 (20130101) C08J 2401/10 (20130101) C08J 2405/08 (20130101) Compositions of Macromolecular Compounds C08L 1/04 (20130101) C08L 1/04 (20130101) C08L 1/04 (20130101) C08L 1/04 (20130101) C08L 1/10 (20130101) C08L 1/10 (20130101) C08L 1/10 (20130101) C08L 1/10 (20130101) C08L 5/08 (20130101) C08L 5/08 (20130101) C08L 5/08 (20130101) C08L 5/08 (20130101) C08L 2201/06 (20130101) C08L 2203/16 (20130101) C08L 2205/02 (20130101) C08L 2205/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11366042 | Fraden et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BRANDEIS UNIVERSITY (Waltham, Massachusetts) |
| ASSIGNEE(S) | Brandeis University (Waltham, Massachusetts) |
| INVENTOR(S) | Seth Fraden (Newton, Massachusetts); Michael Heymann (Hamburg, Germany); Markus Ludwig (Waltham, Massachusetts) |
| ABSTRACT | Microfluidic devices and methods for investigating crystallization and/or for controlling a reaction or a phase transition are disclosed. In one embodiment, the microfluidic device includes a reservoir layer; a membrane disposed on the reservoir layer; a wetting control layer disposed on the membrane; and a storage layer disposed on the wetting control layer, wherein the wetting control layer and the storage layer define a microfluidic channel comprising an upstream portion, a downstream portion, a first fluid path in communication with the upstream and the downstream portions, and a storage well positioned within the first fluid path, wherein the wetting control layer includes a fluid passageway in communication with the storage well and the membrane, and wherein the wetting control layer wets a first fluid introduced into the microfluidic channel, the first fluid comprising a hydrophilic, lipophilic, fluorophilic or gas phase as the continuous phase in the microfluidic channel. |
| FILED | Monday, February 08, 2021 |
| APPL NO | 17/170022 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Separation B01D 9/0036 (20130101) B01D 9/0072 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 3/502723 (20130101) B01L 3/502761 (20130101) B01L 3/502784 (20130101) B01L 2200/025 (20130101) B01L 2200/141 (20130101) B01L 2300/088 (20130101) B01L 2300/123 (20130101) B01L 2300/161 (20130101) B01L 2300/0829 (20130101) B01L 2300/0887 (20130101) B01L 2300/1894 (20130101) B01L 2400/0487 (20130101) B01L 2400/0688 (20130101) Apparatus for Enzymology or Microbiology; C12M 3/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/28 (20130101) Original (OR) Class G01N 23/20025 (20130101) G01N 2001/4016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11366114 | Hughes et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MONTANA MOLECULAR LLC (Bozeman, Montana) |
| ASSIGNEE(S) | Montana Molecular LLC (Bozeman, Montana) |
| INVENTOR(S) | Thomas E. Hughes (Bozeman, Montana); Paul H. Tewson (Bozeman, Montana); Anne Marie Quinn (Bozemen, Montana) |
| ABSTRACT | Described herein are novel fluorescent sensors for cyclic adenosine monophosphate (cAMP) that are based on single fluorescent proteins. These sensors use less visible spectrum than FRET-based sensors, produce robust changes in fluorescence, and can be combined with one another, or with other sensors, in a multiplex assay on standard fluorescent plate readers or live cell imaging systems. |
| FILED | Tuesday, November 04, 2014 |
| APPL NO | 15/033147 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/00 (20130101) C07K 2319/60 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/542 (20130101) G01N 33/566 (20130101) Original (OR) Class G01N 33/582 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11366302 | Pau et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of the University of Arizona (Tucson, Arizona) |
| INVENTOR(S) | Stanley Pau (Tucson, Arizona); Rongguang Liang (Tucson, Arizona) |
| ABSTRACT | Apparatus and methods are disclosed for measuring polarization properties and phase information, for example as can be used in microscopy applications. According to one example of the disclosed technology, an apparatus includes a light source, an interferometer configured to receive light generated by the light source and split the received light into two split beam outputs. The split beam outputs including combined, interfering light beams. Two light sensors, each including a polarization-sensitive focal plane array receive a respective one of the split beam outputs from the interferometer. Thus, some examples of the disclosed technology allows for simultaneous or concurrent measurement of properties of light including intensity, wavelength, polarization, and phase. The polarization-sensitive focal plane array includes a number of macropixels, each of which includes superpixels having different polarization filtering properties, each of which includes one or more pixels, which comprise filters for different colors. |
| FILED | Friday, September 07, 2018 |
| APPL NO | 16/644987 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 11/331 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/21 (20130101) G01N 2021/216 (20130101) Optical Elements, Systems, or Apparatus G02B 21/18 (20130101) G02B 21/0092 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11366942 | Gupta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Siemens Corporation (Iselin, New Jersey); Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Siemens Corporation (Iselin, New Jersey); Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Ashish Gupta (Atlanta, Georgia); George Allen (Okinawa, Japan); Jaroslaw Rossignac (Atlanta, Georgia); Suraj Ravi Musuvathy (Princeton Junction, New Jersey); Livio Dalloro (Plainsboro, New Jersey) |
| ABSTRACT | A computer-implemented method for constructing structures using beams bounded by quadric surfaces of revolution includes generating a quador beam within a computer-aided design (CAD) tool. The quador beam comprises two spheres at opposing endpoints, and the beam is bounded by a quadric surface of revolution around an axis of symmetry joining the center of the two spheres. The quadric surface of revolution abuts with tangent continuity with the surface of each of the spheres. Once generated, the quador beam can be visualized in the CAD tool or another display medium. |
| FILED | Tuesday, September 04, 2018 |
| APPL NO | 16/641305 |
| ART UNIT | 2148 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 30/17 (20200101) Original (OR) Class G06F 2111/20 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11367149 | Marculescu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Radu Marculescu (Pittsburgh, Pennsylvania); Huan-Kai Peng (Pittsburgh, Pennsylvania) |
| ABSTRACT | In some aspects, computer-implemented methods of identifying patterns in time-series social-media data. In an embodiment, the method includes applying a deep-learning methodology to the time-series social-media data at a plurality of temporal resolutions to identify patterns that may exist at and across ones of the temporal resolutions. A particular deep-learning methodology that can be used is a recursive convolutional Bayesian model (RCBM) utilizing a special convolutional operator. In some aspects, computer-implemented methods of engineering outcome-dynamics of a dynamic system. In an embodiment, the method includes training a generative model using one or more sets of time-series data and solving an optimization problem composed of a likelihood function of the generative model and a score function reflecting a utility of the dynamic system. A result of the solution is an influence indicator corresponding to intervention dynamics that can be applied to the dynamic system to influence outcome dynamics of the system. |
| FILED | Friday, January 13, 2017 |
| APPL NO | 15/406268 |
| ART UNIT | 2121 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) G06N 20/00 (20190101) G06N 20/10 (20190101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/01 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 51/16 (20130101) H04L 51/32 (20130101) H04L 67/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11367539 | Zheng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | Board of Trustees, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Yuebing Zheng (Austin, Texas); Jingang Li (Austin, Texas) |
| ABSTRACT | Disclosed herein are methods of manipulating particles on solid substrates via optothermally-gated photon nudging. |
| FILED | Tuesday, November 24, 2020 |
| APPL NO | 17/103240 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11368049 | Arnold et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
| INVENTOR(S) | David Patrick Arnold (Gainesville, Florida); Alexandra Garraud (Gainesville, Florida); Nicolas Garraud (Gainesville, Florida) |
| ABSTRACT | The present disclosure relates to systems and methods for electrodynamic wireless power receivers. In some examples, a wireless power receiver electromechanically converts energy from a magnetic field. The wireless power receiver includes a planar suspension structure and at least one magnet. The planar suspension structure is tuned to cause oscillation of the at least one magnet at a resonance frequency based on a frequency of the time-varying magnetic field to generate electrical energy in the wireless power receiver. |
| FILED | Tuesday, November 17, 2020 |
| APPL NO | 17/099904 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/06 (20130101) H01L 41/042 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/005 (20200101) Original (OR) Class H02J 50/12 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11368336 | Porter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | George Porter (San Diego, California); William Mellette (San Diego, California) |
| ABSTRACT | An apparatus for interfacing with a circuit switched network may be configured to detect when a data carrier signal from a circuit switched network is offline. While the data carrier signal from the circuit switched network is offline, the apparatus may send, to a network element coupled with the circuit switched network via the apparatus, control packets indicating that the data carrier signal is offline. The apparatus may further maintain an active data carrier signal between the apparatus and the network device by sending, to the network element, protocol idle frames. The apparatus may buffer, at the apparatus, packets sent from the network element to the circuit switched network. Once the data carrier signal is restored, the apparatus may send, to the circuit switched network, control packets indicating that the data carrier signal is online and the packet buffered at the apparatus while the data carrier signal is offline. |
| FILED | Tuesday, July 10, 2018 |
| APPL NO | 16/629781 |
| ART UNIT | 2472 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 12/66 (20130101) Original (OR) Class H04L 45/026 (20130101) H04L 49/552 (20130101) H04L 49/3036 (20130101) H04L 69/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11364527 | Takata et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Keystone Tower Systems, Inc. (Denver, Colorado) |
| ASSIGNEE(S) | Keystone Tower Systems, Inc. (Denver, Colorado) |
| INVENTOR(S) | Rosalind K. Takata (Denver, Colorado); Eric D. Smith (Denver, Colorado); Loren Daniel Bridgers (Golden, Colorado); Daniel Ainge (Boulder, Colorado); Alexander H. Slocum (Bow, New Hampshire) |
| ABSTRACT | A control system for forming a tapered structure includes a sensor providing feedback for a machine for forming a tapered structure including at least three rolls having at least one bend roll and at least two guide rolls. The guide rolls may include rollette banks having a plurality of rollettes. The machine may also include an adjustment mechanism to position at least one of the rolls, where a diameter of the tapered structure being formed is controlled by relative positions of the rolls. The machine may also include a joining element to join edges of a stock of material together as it is rolled through the rolls to form the tapered structure. The control system may also include a controller to receive feedback from the sensor and to send a control signal based on the feedback to the adjustment mechanism for positioning at least one of the rolls. |
| FILED | Tuesday, December 04, 2018 |
| APPL NO | 16/208831 |
| ART UNIT | 3799 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Manufacture of Metal Sheets, Wire, Rods, Tubes or Profiles, Otherwise Than by Rolling; Auxiliary Operations Used in Connection With Metal-working Without Essentially Removing Material B21C 37/122 (20130101) B21C 37/124 (20130101) B21C 37/126 (20130101) B21C 37/128 (20130101) B21C 37/185 (20130101) Original (OR) Class Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 9/0325 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364693 | Sherman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Powdermet, Inc. (Euclid, Ohio) |
| ASSIGNEE(S) | POWDERMET INC. (Euclid, Ohio) |
| INVENTOR(S) | Andrew Sherman (Mentor, Ohio); Haixong Tang (Euclid, Ohio); Brian Doud (Cleveland Heights, Ohio) |
| ABSTRACT | A composite film having a high dielectric permittivity engineered particles dispersed in a high breakdown strength polymer material to achieve high energy density. |
| FILED | Tuesday, March 03, 2020 |
| APPL NO | 16/807975 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 39/02 (20130101) B29C 39/003 (20130101) B29C 39/22 (20130101) B29C 43/24 (20130101) B29C 48/022 (20190201) B29C 49/0005 (20130101) B29C 55/04 (20130101) B29C 55/12 (20130101) B29C 55/28 (20130101) B29C 70/60 (20130101) Original (OR) Class B29C 70/882 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2105/162 (20130101) B29K 2509/02 (20130101) B29K 2995/0006 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/34 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/005 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/00 (20130101) C08K 2201/011 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/12 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 4/18 (20130101) H01G 4/32 (20130101) H01G 4/33 (20130101) H01G 4/186 (20130101) H01G 4/206 (20130101) H01G 4/306 (20130101) H01G 4/1227 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/04 (20130101) H01M 4/64 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11366114 | Hughes et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MONTANA MOLECULAR LLC (Bozeman, Montana) |
| ASSIGNEE(S) | Montana Molecular LLC (Bozeman, Montana) |
| INVENTOR(S) | Thomas E. Hughes (Bozeman, Montana); Paul H. Tewson (Bozeman, Montana); Anne Marie Quinn (Bozemen, Montana) |
| ABSTRACT | Described herein are novel fluorescent sensors for cyclic adenosine monophosphate (cAMP) that are based on single fluorescent proteins. These sensors use less visible spectrum than FRET-based sensors, produce robust changes in fluorescence, and can be combined with one another, or with other sensors, in a multiplex assay on standard fluorescent plate readers or live cell imaging systems. |
| FILED | Tuesday, November 04, 2014 |
| APPL NO | 15/033147 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/00 (20130101) C07K 2319/60 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/542 (20130101) G01N 33/566 (20130101) Original (OR) Class G01N 33/582 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11363825 | Harte et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Federico Miguel Harte (Port Matilda, Pennsylvania); Michelle Tran (Winnipeg, Canada); John Coupland (State College, Pennsylvania); Robert Roberts (State College, Pennsylvania); Greg Ziegler (State College, Pennsylvania) |
| ABSTRACT | Compositions and methods that relate to improved chocolate milk are provided. The chocolate milk may be shelf stable and k-carrageenan free. The chocolate milk does not undergo visually detectable phase separation for at least 7 days. The chocolate milk that does not undergo the visually detectable phase separation contains from 1%-10% micellar casein w/v. Methods for preparing shelf stable k-carrageenan free chocolate milk are also provided and include mixing cocoa powder, sugar, milk, and micellar casein to obtain a mixture, and optionally heating and homogenizing the mixture, and subsequently subjecting the mixture to High Pressure Jet Processing (HPJ) or high pressure homogenization of at least 300 MPa, thereby producing the shelf table k-carrageenan free chocolate milk. The shelf stable k-carrageenan free chocolate milk of produced using such a method may be refrigerated temperature for at least 14 days, and does not undergo detectable phase separation for at least 14 days. |
| FILED | Thursday, March 07, 2019 |
| APPL NO | 16/295749 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Cocoa; Cocoa Products, e.g Chocolate; Substitutes for Cocoa or Cocoa Products; Confectionery; Chewing Gum; Ice-cream; Preparation Thereof A23G 1/46 (20130101) A23G 1/56 (20130101) Original (OR) Class Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) A23V 2250/60 (20130101) A23V 2250/54246 (20130101) A23V 2300/24 (20130101) A23V 2300/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11364285 | Scharf et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Michael E. Scharf (Battle Ground, Indiana); Brittany F. Peterson (Mascoutah, Illinois) |
| ABSTRACT | Methods and compositions for controlling termite populations by leveraging newly discovered mechanisms for symbiont- and host mediated anti-fungal defenses in the termite hind-gut. Such methods may include administering a composition to a termite, the composition formulated to promote protist dysbiosis in the gut of the termite, or silencing specific host or symbiont genes by RNA interference, and exposing the termite to a pathogen, where the composition increases the susceptibility of the termite to the pathogen. Compositions are also provided for the treatment of fungal infections, the composition comprising a medically effective amount of recombinant glycosyl hydrolase family 7 cellulase, as well as methods for utilizing the same. |
| FILED | Friday, March 31, 2017 |
| APPL NO | 15/476523 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 51/00 (20130101) A01N 51/00 (20130101) A01N 63/20 (20200101) A01N 63/30 (20200101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/47 (20130101) Original (OR) Class Enzymes C12Y 302/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 11367321 | Tartal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | William Albert Tartal (Baltimore, Maryland); Gabriel Michael Yessin (Vienna, Virginia) |
| ABSTRACT | Systems, devices, and methods of locking a lockable volume. The lock may comprise a bolt and a slider. The slider moves linearly to move the bolt in position to engage a securement feature. The engagement of the bolt with the securement feature secures the securement feature, thereby locking the door to which the securement feature is attached. |
| FILED | Tuesday, July 17, 2018 |
| APPL NO | 16/037943 |
| ART UNIT | 2684 — Telemetry and Code Generation Vehicles and System Alarms |
| CURRENT CPC | Locks; Accessories Therefor; Handcuffs E05B 17/0037 (20130101) E05B 47/0004 (20130101) E05B 47/026 (20130101) E05B 65/025 (20130101) E05B 77/48 (20130101) E05B 2047/0024 (20130101) E05B 2047/0094 (20130101) Bolts or Fastening Devices for Wings, Specially for Doors or Windows E05C 17/52 (20130101) Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere G07C 9/00912 (20130101) Original (OR) Class G07C 9/00944 (20130101) G07C 2009/00769 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11368814 | Johnson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey C. Johnson (Annapolis, Maryland); Leonetta J. Jackson (Dublin, California); Srinivasa R. Chappidi (Cupertino, California); Dongni S. Growney (Belmont, California); Bijai T. Nidhiri (Fremont, California); Danny Tan (San Francisco, California); Jini J. Thokalath (Foster City, California); Gang Yin (Fremont, California) |
| ABSTRACT | Techniques for tracking an evacuation of a location in an environment that utilizes physical tokens to prove physical presence at the location are presented. The techniques include receiving data representing of subordinates of an evacuation facilitator; receiving physical token based location status information for at least one of the subordinates, where the physical token based location status information is based on electronic readings of the physical tokens; determining based on the physical token based location status information, a physical presence status at the location for the at least one of the subordinates; receiving evacuation status information for each of the at least one of the subordinates that has a physical presence status that indicates a presence at the location; and recording the evacuation status information for each of the at least one of the subordinates that has a physical presence status that indicates a presence at the location. |
| FILED | Tuesday, October 06, 2020 |
| APPL NO | 17/064275 |
| ART UNIT | 2642 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Wireless Communication Networks H04W 4/12 (20130101) H04W 4/021 (20130101) H04W 4/029 (20180201) Original (OR) Class H04W 4/90 (20180201) H04W 12/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 11364360 | Jacobs et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Bryson Jacobs (Quaker Hill, Connecticut); Savannah Lyle (Saint Petersburg, Florida) |
| ABSTRACT | In an example, a ventilator includes an outer container containing liquid, an inverted container submerged in the liquid to provide inverted container space between a closed top and an inner container liquid level; gas supply line to supply breathing gas to the inverted container space; and inhalation line having an inlet in the inverted container space to provide breathing gas to patient. The inverted container moves upward from a first elevation when the inverted container space reaches a hydrostatic delivery pressure and volume of the inverted container space increases. The inverted container stops moving upward and the gas supply line stops supplying when the inverted container reaches a second elevation above the first. Based on a breath demand signal or preset timing, the inhalation line opens to permit flow of breathing gas to the patient at the hydrostatic delivery pressure, lowering the inverted container due to lost buoyancy resulting in sinkage. |
| FILED | Tuesday, November 16, 2021 |
| APPL NO | 17/527904 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/0003 (20140204) A61M 16/16 (20130101) Original (OR) Class A61M 16/208 (20130101) A61M 2205/3348 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 11364321 | Nikkhah et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona); The United States of America as Represented by The Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona); The United States of America as Represented by The Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Mehdi Nikkhah (Scottsdale, Arizona); Ali Navaei (Tempe, Arizona); Raymond Migrino (Phoenix, Arizona) |
| ABSTRACT | A scaffold-free microtissue is disclosed that includes one or more gold nanostructures linked to a functional moiety, wherein the functional moiety is one or more vasculogenic peptides, one or more anti-inflammatory peptides, one or more antiapoptotic peptides, one or more antinecrotic peptides, one or more antioxidant peptides, one or more oligonucleotides, one or more lipid particles, one or more phospholipid particles, one or more liposomes, one or more nanoliposomes, one or more microRNAs, or one or more siRNAs. The scaffold-free microtissue further includes a plurality of cardiac myocytes or cardiac myoblasts, which are conjugated to the one or more gold nanostructures, wherein the plurality of cardiac myocytes or cardiac myoblasts are arranged in a cluster. The scaffold-free microtissue further includes a plurality of fibroblasts, wherein the fibroblasts are arranged in at least one layer of fibroblasts that substantially surrounds the cluster of gold-nanostructure-conjugated cardiac myocytes or gold-nanostructure-conjugated cardiac myoblasts. |
| FILED | Thursday, October 11, 2018 |
| APPL NO | 16/157956 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/22 (20130101) Original (OR) Class A61L 27/26 (20130101) A61L 27/047 (20130101) A61L 27/54 (20130101) A61L 27/3604 (20130101) A61L 27/3804 (20130101) A61L 27/3821 (20130101) A61L 27/3826 (20130101) A61L 27/3873 (20130101) A61L 27/3886 (20130101) A61L 27/3895 (20130101) A61L 2430/20 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0656 (20130101) C12N 5/0658 (20130101) C12N 2501/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11367539 | Zheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | Board of Trustees, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Yuebing Zheng (Austin, Texas); Jingang Li (Austin, Texas) |
| ABSTRACT | Disclosed herein are methods of manipulating particles on solid substrates via optothermally-gated photon nudging. |
| FILED | Tuesday, November 24, 2020 |
| APPL NO | 17/103240 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
11364264 — Ex vivo antigen-presenting cells or activated CD-positive T cells for treatment of cancer
| US 11364264 | Poznansky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Mark C. Poznansky (Newton Center, Massachusetts); Jeffrey A. Gelfand (Cambridge, Massachusetts) |
| ABSTRACT | This disclosure is directed to methods of preparing dendritic cells or other CD40 bearing antigen-presenting cells and methods of treating cancer by using the dendritic cells or other antigen-presenting cells in combination with anti-chemorepellant agents. This disclosure is further directed to methods of preparing T cells and methods of treating cancer, by activated T cells optionally in combination with anti-chemorepellant agents. The antigen presenting cells of the disclosure are activated by incubation with cancer cells and fusion proteins. The T cells of the disclosures are activated by incubation with activated antigen-presenting cells that were activated by incubation with cancer cells and a fusion protein. In particular, the fusion protein comprises an antigen-binding domain, e.g., an antibody or antibody fragment, and a stress protein domain. |
| FILED | Friday, September 08, 2017 |
| APPL NO | 16/331846 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/15 (20130101) Original (OR) Class A61K 39/001168 (20180801) A61K 45/06 (20130101) A61K 2039/892 (20180801) A61K 2039/6043 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/47 (20130101) C07K 16/3069 (20130101) C07K 2319/30 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0639 (20130101) C12N 2501/07 (20130101) C12N 2501/998 (20130101) C12N 2502/30 (20130101) C12N 2502/1121 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11367786 | Pan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Andrew S. Pan (Los Angeles, California) |
| ABSTRACT | A semiconductor device. In some embodiments, the semiconductor device includes a back gate layer; a buffer layer, on the back gate layer; a device quantum well layer, on the buffer layer; a cap layer, on the device quantum well layer; a top layer, on the cap layer; a first doped region of a first conductivity type, extending at least part-way through the device quantum well layer; a second doped region, of a second conductivity type, within the buffer layer; and a third doped region, of the second conductivity type extending from the top layer to the second doped region. The top layer may include a dielectric layer, and, in the dielectric layer, a plurality of conductive elements, including one or more dot gates, an ohmic contact, a bath gate, a supply gate, and a halo contact. |
| FILED | Monday, October 26, 2020 |
| APPL NO | 17/080752 |
| ART UNIT | 2898 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/122 (20130101) H01L 29/775 (20130101) Original (OR) Class H01L 29/66439 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11368219 | Wolff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Applied Signal Technology, Inc. (Sunnyvale, California) |
| ASSIGNEE(S) | Raytheon Applied Signal Technology, Inc. (Sunnyvale, California) |
| INVENTOR(S) | Vincent Wolff (Mountain View, California); Kevin Lundgreen (Fruit Heights, Utah) |
| ABSTRACT | A polarization dependent loss (PDL) compensation device for an optical system can be configured to output a compensating PDL to at least partially cancel a PDL of the optical system. In certain embodiments, the device can include a first polarization controller configured to modify a state of polarization of an optical signal, a PDL emulator disposed upstream of the first polarization controller and configured to output the compensating PDL upstream of the first polarization controller, and a second polarization controller disposed upstream of the PDL emulator and configured to modify a state of polarization of the optical signal upstream of the PDL emulator. |
| FILED | Friday, November 20, 2020 |
| APPL NO | 17/100583 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/2793 (20130101) Transmission H04B 10/038 (20130101) H04B 10/2569 (20130101) H04B 10/2572 (20130101) Original (OR) Class H04B 10/6161 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, June 21, 2022.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20220621.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page