FedInvent™ Patents

Patent Details for Tuesday, June 28, 2022 

This page was updated on Thursday, June 30, 2022 at 07:28 PM GMT

Department of Health and Human Services (HHS) 

US 11369261 Larin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Sea Systems Command (NAVSEA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Human Genome Research Institute (NHGRI)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) University of Houston System (Houston, Texas)
ASSIGNEE(S) UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas)
INVENTOR(S) Kirill V. Larin (Friendswood, Texas);  Jiasong Li (Houston, Texas);  Manmohan Singh (Houston, Texas);  Chen Wu (Houston, Texas);  Salavat Aglyamov (Austin, Texas)
ABSTRACT An excitation force (internal or external) and phase-sensitive optical coherence elastography (OCE) system, used in conjunction with a data analyzing algorithm, is capable of measuring and quantifying biomechanical parameters of tissues in situ and in vivo. The method was approbated and demonstrated on an example of the system that combines a pulsed ultrasound system capable of producing an acoustic radiation force on the crystalline lens surface and a phase-sensitive optical coherence tomography (OCT) system for measuring the lens displacement caused by the acoustic radiation force. The method allows noninvasive and nondestructive quantification of tissue mechanical properties. The noninvasive measurement method also utilizes phase-stabilized swept source optical coherence elastography (PhS-SSOCE) to distinguish between tissue stiffness, such as that attributable to disease, and effects on measured stiffness that result from external factors, such as pressure applied to the tissue. Preferably, the method is used to detect tissue stiffness and to evaluate the presence of its stiffness even if it is affected by other factors such as intraocular pressure (TOP) in the case of cornea, sclera, or the lens. This noninvasive method can evaluate the biomechanical properties of the tissues in vivo for detecting the onset and progression of degenerative or other diseases (such as keratoconus).
FILED Tuesday, September 03, 2019
APPL NO 16/558413
ART UNIT 2872 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 3/16 (20130101)
A61B 3/0025 (20130101) Original (OR) Class
A61B 3/102 (20130101)
A61B 3/165 (20130101)
A61B 5/0051 (20130101)
A61B 5/0053 (20130101)
A61B 5/0066 (20130101)
A61B 5/0093 (20130101)
A61B 5/0097 (20130101)
A61B 8/10 (20130101)
A61B 8/485 (20130101)
A61B 2576/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369295 Lakowicz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of General Medical Sciences (NIGMS)
NIH Office of the Director (NIHOD)
APPLICANT(S) University of Maryland, Baltimore (Baltimore, Maryland)
ASSIGNEE(S) UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland)
INVENTOR(S) Joseph R. Lakowicz (Ellicott City, Maryland);  Ramachandram Badugu (Ellicott City, Maryland);  E. Albert Reece (Lutherville, Maryland)
ABSTRACT A material, article, system and method include a probe composition that includes a hydrophobic portion, a hydrophilic portion, an analyte-binding portion and a fluorophore portion. The analyte-binding portion is configured to bind to an analyte in an aqueous solution. The fluorophore portion is configured to change an optical property of fluorescent light emitted in response to incident excitation light when the probe composition changes between a first state in which the analyte is not bound to the analyte-binding portion and a second state in which the analyte binds to the analyte-binding portion. A material includes the probe composition and a silicone hydrogel substrate having a hydrogel network that allows flow of aqueous solution through the solution and a silicone network that occupies interstices of the hydrogel network. A contact lens having the material enables remote detection of glucose concentration in tear fluid of a subject.
FILED Thursday, July 20, 2017
APPL NO 16/319179
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/1495 (20130101) Original (OR) Class
A61B 5/6821 (20130101)
A61B 5/14507 (20130101)
A61B 5/14532 (20130101)
A61B 5/14546 (20130101)
A61B 5/14556 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 5/025 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369343 Li et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Yilei Li (Palo Alto, California);  Steven Chu (Menlo Park, California)
ABSTRACT Nonlinear ultrasound imaging systems and methods are disclose. In one aspect, a nonlinear ultrasound imaging system includes a first transducer configured to transmit a first ultrasound signal along a scan line, a second transducer configured to sweep a second ultrasound signal along the scan line such that the first and second ultrasound signals intersect at a plurality of voxels, and a third transducer configured to receive echoes associated with interactions of the first and second ultrasound signals at the plurality of voxels. The nonlinear ultrasound imaging system further includes a processor configured to generate an ultrasound image based on the echoes.
FILED Monday, December 23, 2019
APPL NO 16/725970
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 8/06 (20130101)
A61B 8/14 (20130101) Original (OR) Class
A61B 8/481 (20130101)
A61B 8/488 (20130101)
A61B 8/4477 (20130101)
A61B 8/4488 (20130101)
A61B 8/4494 (20130101)
A61B 8/5207 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/52038 (20130101)
G01S 15/8913 (20130101)
G01S 15/8915 (20130101)
G01S 15/8952 (20130101)
G01S 15/8995 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369385 Maitland et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas);  SHAPE MEMORY MEDICAL, INC (Santa Clara, California)
ASSIGNEE(S) THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas);  SHAPE MEMORY MEDICAL, INC (Santa Clara, California)
INVENTOR(S) Duncan J. Maitland (College Station, Texas);  Todd L. Landsman (San Jose, California);  Jennifer N. Rodriguez (Fremont, California);  Anthony J. Boyle (College Station, Texas);  Alan C. Glowczwski (College Station, Texas);  Mark A. Wierzbicki (College Station, Texas)
ABSTRACT An embodiment includes a system comprising: an outer conduit; a shape memory polymer (SMP) foam; a metal backbone including: (a)(i) a first portion that extends from the SMP foam proximal end to the SMP foam distal end and which is generally covered by the SMP foam, and (a)(ii) a distal portion that extends distally from the SMP foam distal end and which is not covered by the SMP foam; wherein: (b)(i) SMP foam and the metal backbone are both included within the outer conduit adjacent to the outer conduit distal end; (b)(ii) the metal backbone distal portion transitions from a secondary shape that is uncoiled to a primary shape that is coiled; and (b)(iii) the metal backbone distal portion is in the metal backbone distal portion secondary shape and is located between the SMP foam distal end and the distal end of the outer conduit.
FILED Friday, September 25, 2020
APPL NO 17/032270
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/1215 (20130101)
A61B 17/1219 (20130101) Original (OR) Class
A61B 17/12109 (20130101)
A61B 17/12172 (20130101)
A61B 2017/00526 (20130101)
A61B 2017/00871 (20130101)
A61B 2017/00898 (20130101)
A61B 2017/12063 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369399 Bagwell et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) Actuated Medical, Inc. (Bellefonte, Pennsylvania)
ASSIGNEE(S) Actuated Medical, Inc. (Bellefonte, Pennsylvania)
INVENTOR(S) Roger B Bagwell (Bellefonte, Pennsylvania);  Timothy J Higgins (Mingoville, Pennsylvania);  Eric J Hopkins (Bellefonte, Pennsylvania);  Casey A Scruggs (Bellefonte, Pennsylvania);  Kevin A Snook (State College, Pennsylvania)
ABSTRACT A device for engaging tissue includes a body disposable around the distal end of a medical instrument, such as an endoscope, and a handpiece. The body includes a primary channel for receiving the medical instrument and at least one arm channel for receiving an arm therethrough. At least one arm extends through the arm channel of the body and proximally to the handpiece. The arm includes an engagement member distally of the body, and may further include a bend between the body and engagement member. The engagement member is movable between a first position not contacting tissue and a second position contacting tissue. With multiple engagement members, the engagement members are farther apart from one another in the first position and closer together in the second position. Movement of the engagement members is controlled by selective and independent movement of the corresponding arms by rotational and/or translational motion.
FILED Friday, July 13, 2018
APPL NO 16/034965
ART UNIT 3795 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 1/0014 (20130101)
A61B 1/015 (20130101)
A61B 1/00087 (20130101)
A61B 1/00089 (20130101)
A61B 1/00094 (20130101)
A61B 17/30 (20130101) Original (OR) Class
A61B 17/0218 (20130101)
A61B 2017/00269 (20130101)
A61B 2017/00296 (20130101)
A61B 2017/305 (20130101)
A61B 2017/00367 (20130101)
A61B 2017/00477 (20130101)
A61B 2017/00818 (20130101)
A61B 2017/2901 (20130101)
A61B 2017/2926 (20130101)
A61B 2217/005 (20130101)
A61B 2217/007 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369569 Klibanov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
ASSIGNEE(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S) Alexander L. Klibanov (Charlottesville, Virginia);  Brent A. French (Charlottesville, Virginia);  Kimberly A. Kelly (Crozet, Virginia);  Siva Sai Krishna Dasa (Charlottesville, Virginia)
ABSTRACT Isolated peptides targeting cardiovascular disease are described herein or one or more conservative amino acid substitutions, deletions or additions of such peptides and methods of use thereof for delivering payloads to specific cell types or tissues.
FILED Wednesday, June 15, 2016
APPL NO 15/737047
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/127 (20130101) Original (OR) Class
A61K 47/62 (20170801)
A61K 47/64 (20170801)
A61K 47/6911 (20170801)
A61K 47/6913 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/00 (20180101)

Peptides
C07K 7/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369575 Ma et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
ASSIGNEE(S) The Board of Regents of the University of Oklahoma (Norman, Oklahoma);  Virginia Commonwealth University, Intellectual Property Foundation (Richmond, Virginia)
INVENTOR(S) Jian-xing Ma (Edmond, Oklahoma);  Fangfang Qiu (Oklahoma City, Oklahoma);  Qingguo Xu (Glen Allen, Virginia);  Tuo Meng (Richmond, Virginia)
ABSTRACT Pharmaceutical particles having an inner portion comprising an agonist of peroxisome proliferator-activated receptor α (PPARα) and a biodegradable polymer; and an outer coating comprising an emulsifier which surrounds the inner portion, wherein the agonist may be a fibrate, and the particle contains at least about 5 wt % to about 25 wt % of the agonist, and wherein the particle has a sustained delayed release of the agonist in a range of at least about 1 to 12 months when in an aqueous solution or physiological environment. The pharmaceutical particles may be used, for example, to treat diseases and conditions such as ocular disorders which benefit from PPARα agonism.
FILED Wednesday, March 18, 2020
APPL NO 16/822964
ART UNIT 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5138 (20130101) Original (OR) Class
A61K 9/5161 (20130101)
A61K 31/216 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369586 Bicker et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) MIDDLE TENNESSEE STATE UNIVERSITY (Murfreesboro, Tennessee)
ASSIGNEE(S) Middle Tennessee State University (Murfreesboro, Tennessee)
INVENTOR(S) Kevin L. Bicker (Rockvale, Tennessee);  Madyson P. Middleton (Tennessee Ridge, Tennessee);  Scott A. Armstrong (Memphis, Tennessee)
ABSTRACT Described herein are antifungal peptoids, the development and characterization of the antifungal peptoids, methods of making the antifungal peptoids, and methods of using the antifungal peptoids. In some embodiments, the antifungal peptoids may be administered to a subject infected with or at risk of being infected with pathogenic fungi including, for example Cryptococcus spp. In some embodiments, the Cryptococcus spp. may include C. neoformans or C. gattii or both.
FILED Wednesday, December 18, 2019
APPL NO 16/718577
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/381 (20130101) Original (OR) Class
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/10 (20180101)

Heterocyclic Compounds
C07D 333/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369588 Rabinowitz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) The Trustees of Princeton University (Princeton, New Jersey)
ASSIGNEE(S) The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S) Joshua D. Rabinowitz (Princeton, New Jersey);  Jing Fan (Madison, Wisconsin);  Gregory S. Ducker (Rocky Hill, New Jersey)
ABSTRACT A 10-formyl-THF pathway for producing NADPH is useful in the diagnosis and treatment of cancer and metabolic disease, in the development of new antineoplastic agents and/or regimens, in the development of new methods for measuring metabolic pathway activity, and in the development of new therapeutics for treating metabolic disease.
FILED Thursday, September 15, 2016
APPL NO 15/266596
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/198 (20130101)
A61K 31/198 (20130101)
A61K 31/513 (20130101)
A61K 31/513 (20130101)
A61K 31/517 (20130101)
A61K 31/517 (20130101)
A61K 31/519 (20130101)
A61K 31/519 (20130101)
A61K 31/4162 (20130101) Original (OR) Class
A61K 31/4162 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369596 Trotti et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Thomas Jefferson University (Philadelphia, Pennsylvania)
ASSIGNEE(S) Thomas Jefferson University (Philadelphia, Pennsylvania)
INVENTOR(S) Davide Trotti (Bala Cynwyd, Pennsylvania);  Piera Pasinelli (Bala Cynwyd, Pennsylvania);  Michael R. Jablonski (Philadelphia, Pennsylvania)
ABSTRACT The present invention provides a method of treating or ameliorating a neurodegenerative disease in a mammal, the method comprising administering to the mammal a therapeutically effective amount of a neurodegenerative disease drug, wherein the drug is a substrate of an ABC transporter inhibitor, wherein the mammal is further administered a therapeutically effective amount of an ABC transporter inhibitor, whereby the neurodegenerative disease is treated in the mammal. In certain embodiments, the neurodegenerative disease comprises at least one selected from the group consisting of spinal cord injury, Alzheimer's disease, Parkinson's disease, Huntington's disease, prion disease, amyotrophic lateral sclerosis, a tauopathy, and chronic traumatic encephalopathy.
FILED Thursday, February 28, 2019
APPL NO 16/289273
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/55 (20130101)
A61K 31/55 (20130101)
A61K 31/428 (20130101)
A61K 31/428 (20130101)
A61K 31/473 (20130101) Original (OR) Class
A61K 31/473 (20130101)
A61K 31/496 (20130101)
A61K 31/496 (20130101)
A61K 31/4725 (20130101)
A61K 31/4725 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369607 Karp et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
ASSIGNEE(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Jeffrey M. Karp (Brookline, Massachusetts);  Robert S. Langer (Newton, Massachusetts);  Xiaolei Yin (Quincy, Massachusetts);  Nitin Joshi (Boston, Massachusetts)
ABSTRACT Method and compositions for inducing the self-renewal of stem/progenitor supporting cells comprised by a cochlear cell population, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into hair cells.
FILED Friday, January 24, 2020
APPL NO 16/752256
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0046 (20130101)
A61K 31/19 (20130101)
A61K 31/19 (20130101)
A61K 31/55 (20130101)
A61K 31/167 (20130101)
A61K 31/167 (20130101)
A61K 31/422 (20130101)
A61K 31/422 (20130101)
A61K 31/437 (20130101)
A61K 31/437 (20130101)
A61K 31/506 (20130101) Original (OR) Class
A61K 31/506 (20130101)
A61K 31/4709 (20130101)
A61K 31/4709 (20130101)
A61K 31/5377 (20130101)
A61K 31/5517 (20130101)
A61K 31/5517 (20130101)
A61K 33/00 (20130101)
A61K 33/00 (20130101)
A61K 35/36 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/062 (20130101)
C12N 5/0627 (20130101)
C12N 2501/11 (20130101)
C12N 2501/42 (20130101)
C12N 2501/105 (20130101)
C12N 2501/115 (20130101)
C12N 2501/415 (20130101)
C12N 2501/727 (20130101)
C12N 2501/999 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369609 Goodwin
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Yale University (New Haven, Connecticut)
ASSIGNEE(S) YALE UNIVERSITY (New Haven, Connecticut)
INVENTOR(S) Julie Goodwin (Guilford, Connecticut)
ABSTRACT Compositions and methods for treating cardiovascular diseases and dyslipidemias are provided. The compositions can inhibit Wnt signaling and can reduce inflammation. The levels of cholesterol can be reduced when the compositions are administered to a subject, such as a human.
FILED Friday, May 01, 2020
APPL NO 16/864521
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/506 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369614 Luo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) The Research Foundation for the State University of New York (Syracuse, New York)
ASSIGNEE(S) The Research Foundation for the State University of New York (Syracuse, New York)
INVENTOR(S) Juntao Luo (Jamesville, New York);  Dandan Guo (Syracuse, New York);  Changying Shi (Jamesville, New York)
ABSTRACT Provided herein are compositions and nanocarriers comprising linear-dendritic telodendrimers (TD) containing riboflavin. The nanocarriers and compositions have desirable loading properties and stabilized structure and can be used for efficient in vivo delivery.
FILED Friday, January 19, 2018
APPL NO 16/478789
ART UNIT 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0014 (20130101)
A61K 9/0019 (20130101)
A61K 9/0043 (20130101)
A61K 9/146 (20130101)
A61K 31/75 (20130101)
A61K 31/525 (20130101) Original (OR) Class
A61K 31/704 (20130101)
A61K 47/34 (20130101)
A61K 47/56 (20170801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369618 Ridky et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
INVENTOR(S) Todd Ridky (Bryn Mawr, Pennsylvania);  Christopher Natale (Philadelphia, Pennsylvania);  Jeffrey Winkler (Wynnewood, Pennsylvania)
ABSTRACT The present invention includes compounds, compositions and methods that are useful for preventing or treating melanoma or any other cancer in a subject, such as a GPCR-expressing cancer. In certain embodiments, the compounds comprise estrogen (including estrogen derivatives or analogues), a selective GPER agonist and/or another G-protein coupled receptor (GPCR) agonist that increases cancer cell differentiation.
FILED Wednesday, May 31, 2017
APPL NO 16/310198
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/19 (20130101)
A61K 31/165 (20130101)
A61K 31/167 (20130101)
A61K 31/565 (20130101) Original (OR) Class
A61K 31/4045 (20130101)
A61K 38/15 (20130101)
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369622 Leis et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Northwestern University (Evanston, Illinois);  THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York)
ASSIGNEE(S) Northwestern University (Evanston, Illinois);  THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York)
INVENTOR(S) Jonathan Leis (Chicago, Illinois);  Carol Carter (Huntington, New York)
ABSTRACT A compound having an antiviral activity for inhibiting release of an enveloped virus from a cell is disclosed, including methods of inhibiting release of an enveloped virus from a cell. The antiviral activity of the compound includes inhibiting formation of an associative complex or disrupting formation of an associative complex. The associative complex comprises an L-domain motif of the enveloped virus and at least one cellular polypeptide, or fragment thereof, capable of binding the L-domain motif of the enveloped virus.
FILED Wednesday, August 05, 2020
APPL NO 16/985965
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/53 (20130101)
A61K 31/65 (20130101) Original (OR) Class
A61K 31/165 (20130101)
A61K 31/415 (20130101)
A61K 31/437 (20130101)
A61K 31/4035 (20130101)
A61K 31/4439 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369634 Pusic et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Institute of Child Health and Human Development (NICHD)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The University of Chicago (Chicago, Illinois)
ASSIGNEE(S) The University of Chicago (Chicago, Illinois)
INVENTOR(S) Kae M. Pusic (Chicago, Illinois);  Yelena Y. Grinberg (Chicago, Illinois);  Richard P. Kraig (Chicago, Illinois);  Aya D. Pusic (Chicago, Illinois)
ABSTRACT Methods and compositions involving exosomes or lipid nanovesicles are provided. For example, certain aspects relate to compositions comprising exosomes obtained from cells that have been induced to undergo oxidative stress or stimulated. Furthermore, some aspects of the invention provide methods of treating a subject at risk or having a demyelinating disorder using the compositions.
FILED Monday, January 28, 2019
APPL NO 16/259563
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5068 (20130101)
A61K 31/7088 (20130101)
A61K 35/15 (20130101) Original (OR) Class
A61K 35/30 (20130101)
A61K 35/35 (20130101)
A61K 48/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0618 (20130101)
C12N 15/88 (20130101)
C12N 15/111 (20130101)
C12N 15/113 (20130101)
C12N 2310/14 (20130101)
C12N 2310/141 (20130101)
C12N 2320/31 (20130101)
C12N 2320/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369641 Chan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Charles K. F. Chan (Redwood City, California);  Andrew Stephen Lee (Palo Alto, California);  Michael T. Longaker (Atherton, California);  Irving L. Weissman (Stanford, California);  Joseph Wu (Stanford, California);  Divya Nag (Palo Alto, California);  Eun Young Seo (San Jose, California)
ABSTRACT Methods, compositions, and kits for producing functional blood vessels, and progenitors thereof are provided. Human disorders of the vascular system are treated by reconstitution of functional vessels in vivo through co-transplantation with supporting niche stromal cells for treatment of ischemic injury in the peripheral limbs and heart. The cell populations of the invention, when engrafted into a recipient, anastomose with host vasculature and regenerate functional blood vessels.
FILED Friday, August 25, 2017
APPL NO 16/323079
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 35/28 (20130101)
A61K 35/35 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/10 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0653 (20130101)
C12N 5/0667 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369662 Volkman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin)
ASSIGNEE(S) The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin)
INVENTOR(S) Brian Volkman (Muskego, Wisconsin);  Joshua Ziarek (Boston, Massachusetts);  Christopher Veldkamp (Milwaukee, Wisconsin);  Francis Peterson (Racine, Wisconsin)
ABSTRACT The present invention provides a CXCL121 peptide engineered to resist peptide-induced dimerization by maintaining steric repulsion of the chemokine helix, pharmaceutical compositions thereof, and methods of using said dimer in the treatment of cancer, inflammatory disorders, autoimmune disease, and HIV/AIDS.
FILED Friday, January 17, 2020
APPL NO 16/745809
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/195 (20130101) Original (OR) Class

Peptides
C07K 14/521 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369673 Balint et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Etubics Corporation (Seattle, Washington)
ASSIGNEE(S) Etubics Corporation (Seattle, Washington)
INVENTOR(S) Joseph P. Balint (Seattle, Washington);  Frank R. Jones (Seattle, Washington);  Richard B. Gayle (Seattle, Washington)
ABSTRACT Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided.
FILED Wednesday, September 14, 2016
APPL NO 15/265723
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/191 (20130101)
A61K 38/193 (20130101)
A61K 38/204 (20130101)
A61K 38/208 (20130101)
A61K 38/217 (20130101)
A61K 38/2013 (20130101)
A61K 38/2026 (20130101)
A61K 38/2033 (20130101)
A61K 38/2046 (20130101)
A61K 38/2066 (20130101)
A61K 39/00 (20130101)
A61K 39/0011 (20130101)
A61K 39/12 (20130101) Original (OR) Class
A61K 39/21 (20130101)
A61K 39/235 (20130101)
A61K 39/001106 (20180801)
A61K 39/001182 (20180801)
A61K 2039/54 (20130101)
A61K 2039/57 (20130101)
A61K 2039/545 (20130101)
A61K 2039/575 (20130101)
A61K 2039/5256 (20130101)
A61K 2039/55555 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/005 (20130101)
C07K 14/71 (20130101)
C07K 14/70503 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
C12N 2710/10034 (20130101)
C12N 2710/10321 (20130101)
C12N 2710/10334 (20130101)
C12N 2710/10343 (20130101)
C12N 2710/10371 (20130101)
C12N 2710/20034 (20130101)
C12N 2740/15034 (20130101)
C12N 2740/16234 (20130101)
C12N 2800/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369674 Nabel et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Vaccine Research Center (VRC)
APPLICANT(S) The USA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Gary J. Nabel (Chestnut Hill, Massachusetts);  Wataru Akahata (Kensington, Maryland);  Srinivas Rao (Columbia, Maryland)
ABSTRACT The invention features compositions and methods for the prevention or treatment of one or more strains of Chikungunya virus, as well as other alphavirus-mediated diseases.
FILED Tuesday, July 23, 2019
APPL NO 16/520113
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101) Original (OR) Class
A61K 2039/5258 (20130101)
A61K 2039/55566 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 7/045 (20130101)
C12N 2740/16043 (20130101)
C12N 2770/36123 (20130101)
C12N 2770/36134 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369675 Taubenberger et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Jeffery Karl Taubenberger (Springfield, Virginia);  Louis Merican Schwartzman (Olney, Maryland)
ABSTRACT Universal influenza virus vaccine compositions that include multiple inactivated influenza A viruses are described. The compositions include four or more different influenza A viruses, each virus having a different hemagglutinin (HA) subtype. The vaccine compositions can be used, for example, to elicit an immune response against influenza virus, to immunize a subject against seasonal influenza virus, and/or mitigate a future pandemic by serving as a pre-pandemic vaccine.
FILED Friday, January 18, 2019
APPL NO 16/963718
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/145 (20130101) Original (OR) Class
A61K 2039/543 (20130101)
A61K 2039/5252 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369683 Kalifa et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Jerome Kalifa (Oak Park, Michigan);  Raoul Kopelman (Ann Arbor, Michigan);  Uma Mahesh R. Avula (Ypsilanti, Michigan);  Gwangseong Kim (Ann Arbor, Michigan);  Yong-Eun Koo Lee (Seoul, South Korea);  Hyung Ki Yoon (Ann Arbor, Michigan)
ABSTRACT The present invention relates to nanoparticles. In particular, the present invention provides nanoparticles for clinical (e.g., targeted therapeutic), diagnostic (e.g., imaging), and research applications in the field of cardiology. For example, in some embodiments, the present invention provides a method of treating (e.g., ablating) cardiac tissue, comprising: a) contacting an animal with a nanoparticle comprising a matrix, a toxic (e.g., ablative) agent (e.g., sonosensitizer, chemotherapeutic agent (e.g., doxorubicin or cisplatin), or photosensitizer), and a cardiac targeting moiety; and b) administering an activator of the toxic agent (e.g., light, chemical (e.g., pharmaceutical agent) or ultrasound) to at least a portion of the cardiac tissue (e.g., heart) of the animal to activate the toxic agent.
FILED Tuesday, December 10, 2019
APPL NO 16/708804
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5138 (20130101)
A61K 31/704 (20130101)
A61K 31/5415 (20130101)
A61K 33/243 (20190101)
A61K 38/10 (20130101)
A61K 38/18 (20130101)
A61K 38/20 (20130101)
A61K 38/21 (20130101)
A61K 41/0057 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369687 Medina-Kauwe
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) CEDARS-SINAI MEDICAL CENTER (Los Angeles, California)
ASSIGNEE(S) CEDARS-SINAI MEDICAL CENTER (Los Angeles, California)
INVENTOR(S) Lali K. Medina-Kauwe (Porter Ranch, California)
ABSTRACT Disclosed herein are drug delivery molecules that comprise a ligand that targets a cell surface molecule; a membrane penetration domain; and a payload binding domain; and pharmaceutical compositions comprising the same. Also disclosed are methods of treating cancer, inhibiting the progression of cancer, preventing cancer metastasis, and delivering a therapeutic compound to the brain in a subject in need thereof, the methods comprising identifying a subject in need thereof; providing a composition comprising the drug delivery molecule as disclosed herein; and administering an effective amount of the composition to the subject.
FILED Tuesday, November 20, 2018
APPL NO 16/197240
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/5169 (20130101)
A61K 31/7105 (20130101)
A61K 47/64 (20170801) Original (OR) Class
A61K 47/6803 (20170801)
A61K 47/6851 (20170801)
A61K 47/6929 (20170801)

Peptides
C07K 14/005 (20130101)
C07K 2319/55 (20130101)
C07K 2319/74 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369688 Lam et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Kit S. Lam (Davis, California);  Yuanpei Li (Elk Grove, California);  Gaurav Bharadwaj (Davis, California)
ABSTRACT Methods and compositions are provided for hybrid telodendrimers and nanocarriers containing such hybrid telodendrimers.
FILED Friday, September 15, 2017
APPL NO 16/332950
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5146 (20130101)
A61K 31/192 (20130101)
A61K 31/404 (20130101)
A61K 31/407 (20130101)
A61K 31/421 (20130101)
A61K 47/60 (20170801)
A61K 47/61 (20170801)
A61K 47/549 (20170801)
A61K 47/641 (20170801) Original (OR) Class
A61K 2123/00 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369695 John et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) The Jackson Laboratory (Bar Harbor, Maine)
ASSIGNEE(S) The Jackson Laboratory (Bar Harbor, Maine)
INVENTOR(S) Simon W. M. John (Bar Harbor, Maine);  Peter Alexander Williams (Tremont, Maine)
ABSTRACT The present invention relates to the use of lipid/fat droplet deposits in retinas of a human subject as a biomarker for diagnosing, prognosing, and/or monitoring retinal neurodegeneration with or without an elevated intraocular pressure in glaucoma.
FILED Monday, December 04, 2017
APPL NO 16/466348
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 3/12 (20130101)
A61B 3/13 (20130101)
A61B 3/102 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0014 (20130101)
A61K 9/0019 (20130101)
A61K 49/0017 (20130101) Original (OR) Class
A61K 2123/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369700 Frank et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) IsoTherapeutics Group, LLC (Angleton, Texas)
ASSIGNEE(S) IGL Pharma Inc. (Angleton, Texas)
INVENTOR(S) R. Keith Frank (Lake Jackson, Texas);  Jaime Simon (Angleton, Texas);  Kelli R. Jay (Brazoria, Texas)
ABSTRACT This invention relates to a Kit formulation to prepare a radioactive, bone-seeking, pharmaceutical drug that has high radiochemical purity (RCP) in a fast, facile and reproducible process. The Kit has at least two vials and a two-part buffer system with instructions on how to make the drug formulation in a radiopharmacy. The drug formulations of this invention can be conveniently and reproducibly prepared with better delivery of the drug to mammals, better radiochemical purity of the formulation for use in treating a mammal having bone pain, one or more calcific tumors or needing bone marrow suppression or bone marrow ablation.
FILED Monday, May 04, 2020
APPL NO 16/866001
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/19 (20130101)
A61K 47/02 (20130101)
A61K 51/0482 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369720 Muschalek et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) The Texas A and M University System (College Station, Texas)
ASSIGNEE(S) The Texas A and M University System (College Station, Texas)
INVENTOR(S) Rachael Muschalek (College Station, Texas);  Keith Hearon (Boston, Massachusetts);  Landon D. Nash (Sunnyvale, California);  Duncan J. Maitland (College Station, Texas)
ABSTRACT An embodiment includes a system comprising: a substrate of a medical device; an un-foamed polyurethane coating directly contacting the substrate and fixedly attached to the substrate; a thermoset polyurethane shape memory polymer (SMP) foam, having first and second states, which directly contacts the polyurethane coating and fixedly attaches to the polyurethane coating; wherein the polyurethane coating fixedly attaches the SMP foam to the substrate. Other embodiments are described herein.
FILED Thursday, January 30, 2020
APPL NO 16/777190
ART UNIT 1788 — Miscellaneous Articles, Stock Material
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 17/145 (20130101)
A61L 27/34 (20130101)
A61L 27/34 (20130101)
A61L 27/56 (20130101)
A61L 31/10 (20130101) Original (OR) Class
A61L 31/10 (20130101)
A61L 31/146 (20130101)
A61L 2400/16 (20130101)
A61L 2430/36 (20130101)

Compositions of Macromolecular Compounds
C08L 75/04 (20130101)
C08L 75/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369768 Galbraith et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
Small Business Administration (SBA)
Small Business Technology Transfer (STTR)
APPLICANT(S) Separation Design Group IP Holdings, LLC (Waynesburg, Pennsylvania)
ASSIGNEE(S) SEPARATION DESIGN GROUP IP HOLDINGS, LLC (Waynesburg, Pennsylvania)
INVENTOR(S) Stephen Douglas Galbraith (Waynesburg, Pennsylvania);  Kenneth J. McGowan (Waynesburg, Pennsylvania);  Evonne A. Baldauff (Waynesburg, Pennsylvania);  Elise N. Depetris (Waynesburg, Pennsylvania);  David K. Walker (Waynesburg, Pennsylvania)
ABSTRACT Lightweight, portable oxygen concentrators that operate using an ultra rapid, sub one second, adsorption cycle based on advanced molecular sieve materials are disclosed. The amount of sieve material utilized is a fraction of that used in conventional portable devices. This dramatically reduces the volume, weight, and cost of the device. Innovations in valve configuration, moisture control, case and battery design, and replaceable sieve module are described. Patients with breathing disorders and others requiring medical oxygen are provided with a long lasting, low cost alternative to existing portable oxygen supply devices.
FILED Friday, November 08, 2019
APPL NO 16/678018
ART UNIT 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 16/0003 (20140204)
A61M 16/20 (20130101)
A61M 16/0063 (20140204)
A61M 16/101 (20140204) Original (OR) Class
A61M 16/105 (20130101)
A61M 16/107 (20140204)
A61M 16/0666 (20130101)
A61M 16/0672 (20140204)
A61M 16/0875 (20130101)
A61M 16/1005 (20140204)
A61M 2016/1025 (20130101)
A61M 2202/0208 (20130101)
A61M 2205/02 (20130101)
A61M 2205/42 (20130101)
A61M 2205/75 (20130101)
A61M 2205/3327 (20130101)
A61M 2205/3334 (20130101)
A61M 2205/8206 (20130101)

Separation
B01D 53/02 (20130101)
B01D 53/26 (20130101)
B01D 53/0415 (20130101)
B01D 53/0473 (20130101)
B01D 2253/108 (20130101)
B01D 2253/304 (20130101)
B01D 2256/12 (20130101)
B01D 2257/102 (20130101)
B01D 2259/4533 (20130101)
B01D 2259/4541 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 137/85938 (20150401)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369773 Donahue et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
APPLICANT(S) RITHIM BIOLOGICS, INC. (Woodbine, Maryland)
ASSIGNEE(S) RITHIM BIOLOGICS, INC. (Woodbine, Maryland)
INVENTOR(S) John Kevin Donahue (Holliston, Massachusetts);  Ronald Lee Anderson (Woodbine, Maryland)
ABSTRACT The present invention relates to a targeted cardiac therapy device that can precisely deliver therapeutic compounds to desired locations on, around or within the heart of a patient, and methods of treating conduction system disease, sinus node dysfunction, atrial fibrillation, myocardial infarction, and heart failure, using the described devices to deliver genetically engineered vectors or cells, proteins, stem cells, small molecule pharmaceuticals and biologics.
FILED Thursday, January 11, 2018
APPL NO 16/477169
ART UNIT 3783 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 34/20 (20160201)
A61B 90/361 (20160201)
A61B 2090/3966 (20160201)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 1/0058 (20130101)
A61M 25/0068 (20130101) Original (OR) Class
A61M 25/0082 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369796 Grill et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
APPLICANT(S) Duke University (Durham, North Carolina)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Warren Grill (Durham, North Carolina);  Nikki Pelot (Durham, North Carolina);  Timothy Hoer (Durham, North Carolina)
ABSTRACT The present disclosure provides systems and methods relating to neuromodulation. In particular, the present disclosure provides systems and methods for identifying optimized waveforms for blocking neural conduction. The systems and methods of neuromodulation disclosed herein facilitate the treatment of various diseases associated with pathological neural activity. The optimized waveforms for blocking neural conduction are identified through use of a global optimization algorithm based on predetermined performance criteria. A plurality of waveforms are generated and evaluated for neuronal conduction block using a computational model of extracellular neuronal stimulation, and at least on candidate waveform having an optimized shape capable of blocking neural conduction is identified.
FILED Tuesday, September 25, 2018
APPL NO 16/651231
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/378 (20130101)
A61N 1/3615 (20130101)
A61N 1/36071 (20130101)
A61N 1/36171 (20130101) Original (OR) Class

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 20/30 (20180101)
G16H 50/50 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369936 Ciccia et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Alberto Ciccia (New York, New York);  Pierre Billon (New York, New York)
ABSTRACT The present disclosure provides, inter alia, specially designed DNA adaptors and methods of preparing the same. Methods and kits for carrying out and detecting marker-free precision genome editing and genetic variation using such adaptors are also provided.
FILED Thursday, March 04, 2021
APPL NO 17/192836
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/0046 (20130101) Original (OR) Class
B01J 2219/00315 (20130101)
B01J 2219/00369 (20130101)
B01J 2219/00378 (20130101)
B01J 2219/00387 (20130101)
B01J 2219/00504 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101)

Combinatorial Chemistry; Libraries, e.g Chemical Libraries
C40B 40/06 (20130101)
C40B 60/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369945 Woolley et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Adam T. Woolley (Orem, Utah);  Radim Knob (Sandy, Utah)
ASSIGNEE(S)
INVENTOR(S) Adam T. Woolley (Orem, Utah);  Radim Knob (Sandy, Utah)
ABSTRACT A method and microfluidic device with a porous polymer monolith in a channel of the device with capture affinity element (such as an oligonucleotide complementary to a DNA target from the KPC antibiotic resistance gene) on the monolith surface.
FILED Friday, March 15, 2019
APPL NO 16/355692
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/261 (20130101)
B01J 20/265 (20130101)
B01J 20/28042 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/64 (20130101)
G01N 30/6095 (20130101)
G01N 2030/528 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369966 Anderson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
ASSIGNEE(S) Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) Clifford Anderson (Tempe, Arizona);  Kristen Lee (Mesa, Arizona);  Jacob Messner (Mesa, Arizona);  Laimonas Kelbauskas (Gilbert, Arizona);  Benjamin Ueberroth (Tempe, Arizona);  Yanqing Tian (Tempe, Arizona);  Deirdre Meldrum (Phoenix, Arizona)
ABSTRACT A multi-layer sealing structure for sealing a microwell array defined in or on a substrate includes at least one front compliant layer, a back compliant layer, and a flexural layer arranged between the at least one front compliant layer and the back compliant layer, wherein the at least one front compliant layer is closer than the back compliant layer to microwells of the microwell array. One or more front compliant layers may be optically reflective and/or may embody a sensor layer. The back compliant layer may include an adhesive or various types of rubber, and the flexural layer may include a polymeric material or metal. A multi-layer sealing structure may be separated from a microwell array by peeling. A multi-layer sealing structure allows local disruption of sealing where particle contaminants are present without compromising the sealing performance of an entire microwell array, and without requiring a large sealing force.
FILED Friday, September 16, 2016
APPL NO 15/760984
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/50853 (20130101) Original (OR) Class
B01L 2200/025 (20130101)
B01L 2200/141 (20130101)
B01L 2200/142 (20130101)
B01L 2200/0689 (20130101)
B01L 2300/16 (20130101)
B01L 2300/123 (20130101)
B01L 2300/0627 (20130101)
B01L 2300/0829 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369967 Dasgupta et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Purnendu Dasgupta (Arlington, Texas);  Aditya Das (Arlington, Texas)
ABSTRACT A cartridge comprises a housing; a sample mixing compartment disposed within the housing, the sample mixing compartment comprising: an activation pouch, and a sample collection region; and a gas transporter tube having a first end and a second end, the tube being disposed within the housing adjacent to the sample mixing compartment, wherein the sample mixing compartment is partially defined by a moveable door of the housing, the moveable door providing access to the sample mixing compartment when the door is in an open position and preventing access to the sample mixing compartment when the door is in a closed position; and wherein the door is configured to release contents of the activation pouch upon movement from the open position to the closed position.
FILED Wednesday, April 22, 2020
APPL NO 16/855782
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Mixing, e.g Dissolving, Emulsifying, Dispersing
B01F 29/10 (20220101)
B01F 29/321 (20220101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/52 (20130101) Original (OR) Class
B01L 2200/025 (20130101)
B01L 2300/0858 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/31 (20130101)
G01N 35/1002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11370757 Michael et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Katja Michael (El Paso, Texas);  Chunqlang Li (El Paso, Texas);  Thomas Boland (El Paso, Texas);  Hector P. Del Castillo (El Paso, Texas);  Binata Joddar (El Paso, Texas);  Alfredo Ornelas Sanchez (El Paso, Texas);  Javier Hernandez Ortega (El Paso, Texas);  Irodiel Vinales Lozano (El Paso, Texas);  Philip T. Baily (El Paso, Texas)
ABSTRACT Crosslinkers of an amide or thiocarbamate of 7-nitroindoline were prepared with at least two attached reactive groups for crosslinking capability. The photo-cleavability of the invented crosslinkers is based on the known photolysis behavior of N-acyl-7-nitroindolines, and the photolysis behavior of amides and thiocarbamates of 7-nitroindolines. These crosslinkers enable crosslinking of biopolymers, which can be reversed by illumination with light.
FILED Monday, October 19, 2020
APPL NO 17/074232
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 209/08 (20130101) Original (OR) Class
C07D 403/12 (20130101)
C07D 405/12 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 15/26 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11370769 Hopkins et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Board of Regents of the University of Nebraska (Lincoln, Nebraska);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) Corey Hopkins (Omaha, Nebraska);  Anna Greka (Boston, Massachusetts)
ABSTRACT Provided herein are TRPC5 inhibitors and methods of using the same, e.g., to protect podocytes and/or treat kidney disease.
FILED Friday, September 07, 2018
APPL NO 16/644188
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 13/12 (20180101)

Heterocyclic Compounds
C07D 401/04 (20130101) Original (OR) Class
C07D 401/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11370770 Scheidt et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
ASSIGNEE(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S) Karl A. Scheidt (Evanston, Illinois);  Gary E. Schiltz (Naperville, Illinois);  Matthew R. Clutter (Deerfield, Illinois);  Ada J. Kwong (Evanston, Illinois)
ABSTRACT Disclosed are indazole compounds and derivatives thereof for use as modulators of the activity of mitogen-activated protein kinase 4 (MEK4). The disclosed compounds include 3-Arylindazoles which may be formulated in pharmaceutical composition for treating cell proliferative diseases and disorders associated with MEK4 activity, including cancer.
FILED Wednesday, June 24, 2020
APPL NO 16/910433
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 231/56 (20130101)
C07D 401/04 (20130101) Original (OR) Class
C07D 401/12 (20130101)
C07D 405/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11370794 Candia, III et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Dynavax Technologies Corporation (Berkeley, California)
ASSIGNEE(S) DYNAVAX TECHNOLOGIES CORPORATION (Berkeley, California)
INVENTOR(S) Albert Frederick Candia, III (San Mateo, California);  Richard Thomas Beresis (San Francisco, California);  Robert L. Coffman (Portola Valley, California)
ABSTRACT The invention relates to compounds of formula (I):
or a salt or solvate thereof, wherein the variables are as described herein. Compounds of formula (I), and pharmaceutical compositions thereof, are antagonists of toll-like receptors such as TLR7, TLR8, and/or TLR9. In certain embodiments, compounds of the invention are useful for inhibiting immune response and treating diseases associated with undesirable immune response.
FILED Thursday, November 09, 2017
APPL NO 16/348816
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 45/06 (20130101)

Heterocyclic Compounds
C07D 231/56 (20130101)
C07D 235/18 (20130101)
C07D 487/04 (20130101) Original (OR) Class
C07D 519/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11370814 Kalyanasundaram
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Ramaswamy Kalyanasundaram (Rockford, Illinois)
ABSTRACT The present invention is a multivalent immunogenic composition for immunizing an animal against filariasis. In some embodiments, the antigens of the multivalent immunogenic composition are protein-based, DNA-based, or a combination thereof. This invention also provides a method and kit for detecting a filarial nematode and determining vaccine efficacy.
FILED Thursday, February 13, 2020
APPL NO 16/790277
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/0003 (20130101)
A61K 2039/53 (20130101)
A61K 2039/70 (20130101)
A61K 2039/545 (20130101)
A61K 2039/55505 (20130101)

Peptides
C07K 14/4354 (20130101) Original (OR) Class
C07K 2319/00 (20130101)
C07K 2319/40 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/0065 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56966 (20130101)
G01N 2333/4353 (20130101)
G01N 2469/10 (20130101)
G01N 2469/20 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11370816 Aakalu
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Vinay Aakalu (Chicago, Illinois)
ABSTRACT Synthetic histatins composed of combinations of functional domains of natural histatins separated by exogenous linkers are described as are methods of using endogenous and synthetic histatins for the treatment of ocular diseases or conditions.
FILED Thursday, September 03, 2020
APPL NO 17/011273
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0048 (20130101)
A61K 9/0051 (20130101)
A61K 38/00 (20130101)
A61K 38/06 (20130101)
A61K 38/08 (20130101)
A61K 38/12 (20130101)
A61K 38/1709 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 27/02 (20180101)

Peptides
C07K 14/4723 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11370828 Westendorf et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Interior (DOI)
Interior Business Center (IBC)
Department of Health and Human Services (HHS)
APPLICANT(S) AbCellera Biologies Inc. (Vancouver, Canada);  The United States of America, as represented by the Secretary, Department of Health and Human Svcs. (Bethesda, Maryland)
ASSIGNEE(S) AbCellera Biologies Inc. (Vancouver, Canada);  The United States of America, as represented by the Secretary, Department of Health and Human Svcs. (Bethesda, Maryland)
INVENTOR(S) Kathryn Westendorf (Vancouver, Canada);  Stefanie Zentelis (Vancouver, Canada);  Krithika Muthuraman (Toronto, Canada);  Kevin Jepson (Vancouver, Canada);  Ester Falconer (Vancouver, Canada);  John Mascola (Bethesda, Maryland);  Barney Graham (Bethesda, Maryland);  Kizzmekia Corbett (Bethesda, Maryland);  Julie Ledgerwood (Bethesda, Maryland);  Lingshu Wang (Bethesda, Maryland);  Olubukola Abiona (Bethesda, Maryland);  Wei Shi (Bethesda, Maryland);  Wing-pui Kong (Bethesda, Maryland);  Yi Zhang (Bethesda, Maryland);  Bryan Edward Jones (San Diego, California);  Denisa Foster (San Diego, California);  Julian Davies (La Jolla, California);  Qing Chai (San Diego, California);  Christopher Carl Frye (Bargersville, Indiana);  Ganapathy Gopalrathnam (Fishers, Indiana);  Jörg Hendle (San Diego, California);  John Michael Sauder (Carlsbad, California);  Jeffrey Streetman Boyles (Indianapolis, Indiana);  Anna Pustilnik (San Diego, California)
ABSTRACT Antibodies that bind SARS-CoV spike protein, SARS-CoV-2 spike protein, and methods of using same for treating or preventing conditions associated with SARS or COVID-19 and for detecting SARS-CoV or SARS-CoV-2.
FILED Tuesday, June 22, 2021
APPL NO 17/354434
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/215 (20130101)
A61K 47/6801 (20170801)
A61K 2039/505 (20130101)

Peptides
C07K 16/10 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5091 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11370830 Robbiani et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Rockefeller University (New York, New York)
ASSIGNEE(S) The Rockefeller University (New York, New York)
INVENTOR(S) Davide Robbiani (Brooklyn, New York);  Michel Nussenzweig (New York, New York)
ABSTRACT Antibodies to Zika virus (ZIKV) and dengue 1 virus (DENV1) are provided. The amino acid sequences of the antibodies may be modified. Methods for prophylaxis and/or therapy by administering the antibodies and combinations thereof are provided. Immunological detection methods using the antibodies are provided. Also provided are vaccine compositions which comprise peptides derived from ZIKV and DENV1.
FILED Monday, April 09, 2018
APPL NO 16/603341
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/42 (20130101)
A61K 2039/505 (20130101)

Peptides
C07K 16/1081 (20130101) Original (OR) Class
C07K 2317/21 (20130101)
C07K 2317/33 (20130101)
C07K 2317/34 (20130101)
C07K 2317/55 (20130101)
C07K 2317/76 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
C12N 2770/24022 (20130101)
C12N 2770/24134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11370846 Desir et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Yale University (New Haven, Connecticut)
ASSIGNEE(S) Yale University (New Haven, Connecticut)
INVENTOR(S) Gary Desir (Woodbridge, Connecticut);  Abigail Hunt (Alameda, California);  Jessica O-Rear (Redwood City, California);  Peter Flynn (San Francisco, California)
ABSTRACT The invention provides compositions and methods for binding and inhibiting renalase. In one embodiment, the renalase binding molecule inhibits renalase activity. Thus, in diseases and conditions where a reduction of renalase activity is beneficial, such inhibitory renalase binding molecules act as therapeutics.
FILED Tuesday, April 14, 2020
APPL NO 16/847964
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/39558 (20130101)
A61K 2039/505 (20130101)

Peptides
C07K 16/40 (20130101) Original (OR) Class
C07K 2317/34 (20130101)
C07K 2317/51 (20130101)
C07K 2317/73 (20130101)
C07K 2317/76 (20130101)
C07K 2317/92 (20130101)
C07K 2317/515 (20130101)
C07K 2317/565 (20130101)

Enzymes
C12Y 106/03 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/573 (20130101)
G01N 2333/90209 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11370934 Locklin et al.
FUNDED BY
Department of Health and Human Services (HHS)
Centers for Disease Control and Prevention (CDC)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) University of Georgia Research Foundation, Inc. (Athens, Georgia)
ASSIGNEE(S) University of Georgia Research Foundation, Inc. (Athens, Georgia)
INVENTOR(S) Jason J. Locklin (Bogart, Georgia);  Qiaohong Liu (Athens, Georgia);  Priyadarshini Singha (Athens, Georgia);  Hitesh Handa (Athens, Georgia);  Jitendra Pant (Athens, Georgia);  Marcus J. Goudie (Athens, Georgia);  Sean P. Hopkins (Athens, Georgia)
ABSTRACT Coating compositions, coated articles including the coating compositions, and methods of making the coating compositions and coated articles are provided. In some aspects, the coating compositions are applied to a substrate having nitric oxide-releasing properties. The coating compositions can include copolymers having crosslinking agents that can be activated with mild UV light (about 345 nm to 365 nm) to avoid damaging the substrate while creating strong covalent bonds to the substrate. The copolymers can include hydrophilic repeat units, and in particular zwitterionic repeat units such as repeat units containing phosphorylcholine groups. In some aspects, the coating compositions are applied to a surface of a polymer substrate, wherein the polymer substrate had nitric oxide releasing properties. The coating compositions and the coated articles can have antifouling, antithrombotic, and/or antibacterial properties.
FILED Friday, October 19, 2018
APPL NO 16/757701
ART UNIT 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/197 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 29/16 (20130101)
A61L 29/085 (20130101)
A61L 2300/21 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 133/10 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371003 Ma et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Zhenqiang Ma (Middleton, Wisconsin);  Yei Hwan Jung (Madison, Wisconsin);  Michael Phillips (Stoughton, Wisconsin);  David Gamm (Waunakee, Wisconsin);  Shaoqin Gong (Middleton, Wisconsin)
ABSTRACT Photoreceptor scaffolds and scaffold systems including the photoreceptor scaffolds are described herein. The scaffolds and scaffold systems can be used for transplantation of organized photoreceptor tissue, with or without RPE, which may improve grafted cell survival, integration, and functional visual rescue. Particularly, the photoreceptor scaffold is structured from a biocompatible film, patterned with an array of unique through-holes having a curvilinear cell receiver and at least one cell guide channel.
FILED Friday, February 05, 2016
APPL NO 15/016753
ART UNIT 1796 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 21/08 (20130101)
C12M 23/20 (20130101)
C12M 23/26 (20130101)
C12M 23/30 (20130101)
C12M 25/14 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371008 Murthy
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Northeastern University (Boston, Massachusetts)
ASSIGNEE(S) Northeastern University (Boston, Massachusetts)
INVENTOR(S) Shashi K. Murthy (Newton, Massachusetts)
ABSTRACT Devices, systems, and methods can be used for the automated production of dendritic cells (DC) from dendritic cell progenitors, such as monocytes obtained from peripheral blood, and the automated generation of immunotherapeutic products from those dendritic cells, all within a closed system. The invention makes it possible to obtain sufficient quantities of a subject's own DC for use in preparing and characterizing vaccines, for activating and characterizing the activation state of the subject's immune response, and to aid in preventing and/or treating cancer or infectious disease.
FILED Thursday, May 03, 2018
APPL NO 15/970664
ART UNIT 1799 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/0008 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 23/16 (20130101)
C12M 23/28 (20130101)
C12M 27/00 (20130101)
C12M 29/04 (20130101)
C12M 33/00 (20130101)
C12M 35/08 (20130101)
C12M 41/14 (20130101)
C12M 41/48 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0639 (20130101)
C12N 2501/22 (20130101)
C12N 2501/25 (20130101)
C12N 2501/2306 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371019 Lodish et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Whitehead Institute for Biomedical Research (Cambridge, Massachusetts)
ASSIGNEE(S) Whitehead Institute for Biomedical Research (Cambridge, Massachusetts)
INVENTOR(S) Harvey Lodish (Brookline, Massachusetts);  Xiaofei Gao (Cambridge, Massachusetts);  Hsiang-Ying Lee (Cambridge, Massachusetts)
ABSTRACT A population of early-stage burst-forming unit-eryhtoid (BFU-E) cells characterized by low expression of the Type III Transforming Growth Factor β Receptor (TGFRPIII) and uses thereof for producing red blood cells in vitro, genotoxicity analysis of chemicals, drug sensitivity assessment, and drug development. Also described herein are methods for producing the population of early-stage BFU-E cells and methods for producing red blood cells.
FILED Friday, March 03, 2017
APPL NO 16/081718
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/573 (20130101)
A61K 35/18 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0641 (20130101) Original (OR) Class
C12N 2501/14 (20130101)
C12N 2501/33 (20130101)
C12N 2501/125 (20130101)
C12N 2501/998 (20130101)
C12N 2501/999 (20130101)
C12N 2501/2303 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/502 (20130101)
G01N 33/5014 (20130101)
G01N 33/5044 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371020 Cho
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Emory University (Atlanta, Georgia);  Children's Healthcare of Atlanta, Inc. (Atlanta, Georgia)
ASSIGNEE(S) Emory University (Atlanta, Georgia);  Children's Healthcare of Atlanta, Inc. (Atlanta, Georgia)
INVENTOR(S) Hee Cheol Cho (Johns Creek, Georgia)
ABSTRACT This disclosure relates to methods of generating pacemaker cells for use in therapeutic strategies that address a heart that beats abnormally. In certain embodiments, one mixes cells with an epithelial-to-mesenchymal transformation inhibitor in combination with a nucleic acid encoding a transcription factor such as a vector that encodes a transcription factor such as Tbx18 in operable combination with a eukaryotic promoter to produce pacemaker cells that are then transplanted into the heart.
FILED Tuesday, May 02, 2017
APPL NO 16/098560
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/4709 (20130101)
A61K 31/4709 (20130101)
A61K 31/7088 (20130101)
A61K 31/7088 (20130101)
A61K 35/28 (20130101)
A61K 35/34 (20130101)
A61K 36/9066 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/06 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0657 (20130101) Original (OR) Class
C12N 2501/60 (20130101)
C12N 2501/999 (20130101)
C12N 2506/1315 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371023 Eguchi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S) Asuka Eguchi (Madison, Wisconsin);  Aseem Z. Ansari (Madison, Wisconsin)
ABSTRACT The present invention relates to artificial transcription factors (ATFs) that alter gene expression, including inducing pluripotency in cells or promoting the conversion of cells to specific cell fates. In particular, provided herein is a zinc-finger based ATF library that can be screened in cells by looking for expression of a specific gene (e.g., reporter expression), monitoring for cell surface markers or morphology, or via functional assays.
FILED Wednesday, November 22, 2017
APPL NO 15/821152
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 1/047 (20130101)
C07K 14/4702 (20130101)
C07K 2319/09 (20130101)
C07K 2319/81 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0647 (20130101)
C12N 5/0657 (20130101)
C12N 5/0696 (20130101) Original (OR) Class
C12N 2500/25 (20130101)
C12N 2501/40 (20130101)
C12N 2501/60 (20130101)
C12N 2501/115 (20130101)
C12N 2501/145 (20130101)
C12N 2501/415 (20130101)
C12N 2501/602 (20130101)
C12N 2501/604 (20130101)
C12N 2501/606 (20130101)
C12N 2501/727 (20130101)
C12N 2506/02 (20130101)
C12N 2506/45 (20130101)

Combinatorial Chemistry; Libraries, e.g Chemical Libraries
C40B 40/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371024 Collins et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The USA, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland);  The Research Foundation for the State University of New York (Albany, New York)
ASSIGNEE(S) THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland);  THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York)
INVENTOR(S) Peter L. Collins (Silver Spring, Maryland);  Cyril Le Nouën (Bethesda, Maryland);  Linda G. Brock (Bethesda, Maryland);  Ursula J. Buchholz (Silver Spring, Maryland);  Joshua Marc DiNapoli (Lexington, Massachusetts);  Steffen Mueller (Kings Point, New York);  Eckard Wimmer (E. Setauket, New York)
ABSTRACT Described herein are RSV polynucleotide sequences that make use of multiple codons that are containing silent nucleotide substitutions engineered in multiple locations in the genome, wherein the substitutions introduce a numerous synonymous codons into the genome. Due to the large number of defects involved, the attenuated viruses disclosed herein provide a means of producing attenuated, live vaccines against RSV.
FILED Friday, March 16, 2018
APPL NO 15/924012
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/155 (20130101)
A61K 2039/53 (20130101)
A61K 2039/55 (20130101)
A61K 2039/5254 (20130101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101) Original (OR) Class
C12N 2760/00021 (20130101)
C12N 2760/00034 (20130101)
C12N 2760/00062 (20130101)
C12N 2760/18522 (20130101)
C12N 2760/18534 (20130101)
C12N 2760/18561 (20130101)
C12N 2760/18562 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371025 Steinmetz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) Nicole Steinmetz (San Diego, California);  Daniel Popkin (Cleveland, Ohio)
ABSTRACT A method of non-covalently loading a plant picornavirus is described. The method includes contacting a plant picornavirus in solution with a molar excess of a cargo molecule to load the plant picornavirus with the cargo molecule, and then purifying the loaded plant picornavirus. Examples of cargo molecules include imaging agents, antitumor agents, and antiviral agents. Loaded plant picornaviruses prepared in this manner can be used to delivering cargo molecule to cells.
FILED Monday, March 16, 2020
APPL NO 16/820073
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/40 (20130101)
A61K 31/473 (20130101)
A61K 33/243 (20190101)
A61K 35/76 (20130101)
A61K 47/46 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101) Original (OR) Class
C12N 2770/32041 (20130101)
C12N 2770/32042 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371041 Wilson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
INVENTOR(S) Robert B. Wilson (Wynnewood, Pennsylvania);  Yongping Wang (Wynnewood, Pennsylvania)
ABSTRACT This invention provides sets and libraries of short hairpin ribonucleic acid (shRNA) molecules comprising a double-stranded region of random sequence containing random mismatches, methods of generating same, sets and libraries of expression vectors for same, methods of generating same, and methods for identifying an RNA therapeutic or RNA molecule that has an ability to affect a biological parameter, for identifying a drug target for a disease or disorder of interest, and for identifying a variant of an RNA molecule that has an altered ability to affect a biological parameter of interest.
FILED Monday, April 15, 2019
APPL NO 16/384742
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/10 (20130101)
C12N 15/66 (20130101)
C12N 15/1058 (20130101)
C12N 15/1068 (20130101) Original (OR) Class
C12N 15/1093 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371929 Lo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Yu-Hwa Lo (La Jolla, California);  Yuanyuan Han (La Jolla, California)
ABSTRACT Disclosed are methods, devices, systems and applications for camera-less, high-throughput three-dimensional imaging of particles in motion. In some aspects, a system includes a particle motion device to allow particles to move along a travel path; an optical illumination system to produce an asymmetric illumination area of light in a region of the travel path of a particle that scans over a plurality of sections of the particle at multiple time points while the particle is moving; an optical detection system optically interfaced with the particle motion device to obtain optical signal data associated with different parts of the particle corresponding to the particle's volume during motion in the travel path; and a data processing unit to process the optical signal data obtained by the optical detection system and produce data including information indicative of 3D features of the particle.
FILED Tuesday, February 19, 2019
APPL NO 16/970304
ART UNIT 2486 — Recording and Compression
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/147 (20130101)
G01N 15/1475 (20130101) Original (OR) Class
G01N 2015/145 (20130101)
G01N 2015/1006 (20130101)
G01N 2015/1445 (20130101)

Pictorial Communication, e.g Television
H04N 13/254 (20180501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371958 Yang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
ASSIGNEE(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S) Cheng Yang (Lexington, Massachusetts);  B. Jill Venton (Charlottesville, Virginia)
ABSTRACT An electrochemical device for identifying electroactive analytes. The device includes a substrate; a sample region; a counter electrode; a reference electrode; a working electrode disposed in communication with the substrate, and the working electrode may be an electron conducting fiber. Further, the counter electrode, reference electrode, and working electrode are partially disposed in the sample region configured to be exposed to the electroactive analyte. Further yet, a counter electrode channel, reference electrode channel, and working electrode channel are disposed in the substrate configured to: accommodate each of the counter electrode, reference electrode, and working electrode, respectively, for placement in the respective channels.
FILED Friday, November 10, 2017
APPL NO 16/348916
ART UNIT 1759 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 10/00 (20130101)
B82Y 15/00 (20130101)
B82Y 40/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/327 (20130101)
G01N 27/3278 (20130101) Original (OR) Class

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 51/0048 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371986 Celedon et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Scanogen Inc. (Baltimore, Maryland)
ASSIGNEE(S) SCANOGEN INC. (Baltimore, Maryland)
INVENTOR(S) Alfredo A. Celedon (Columbia, Maryland);  Joseph P. Russell (Odenton, Maryland)
ABSTRACT The present application relates to detection units and methods for detecting one or more target analytes in a sample using a complex formed by a target and first and second probes, wherein the first probe is coupled to a detectable piece, the target is coupled to the first probe and the second probe, and the second probe is coupled to a solid support. Specific binding of the detectable piece to the target analyte can be distinguished from non-specific binding of the detectable piece by measuring the number of detectable pieces that leave their initial location after exposure to a disruptor that uncouples the detectable piece from the solid support.
FILED Thursday, May 23, 2019
APPL NO 16/420231
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/54306 (20130101) Original (OR) Class
G01N 33/54313 (20130101)
G01N 33/54393 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371989 Cantor et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S) DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts)
INVENTOR(S) Harvey Cantor (Boston, Massachusetts);  Jianmei Wu Leavenworth (Hoover, Alabama)
ABSTRACT Methods for diagnosing and prognosing autoimmune diseases and T cell lymphomas are provided, for example by measuring levels of intracellular osteopontin (OPN-i). Also provided are screening methods for identifying activators and inhibitors of the transcription factor Bcl6, which is involved in T cell activation/differentiation. Other aspects of the disclosure provide methods for enhancing adoptive T cell transfer.
FILED Monday, November 19, 2018
APPL NO 16/195586
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101)
C12Q 2600/118 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/564 (20130101) Original (OR) Class
G01N 33/5023 (20130101)
G01N 2333/52 (20130101)
G01N 2333/4703 (20130101)
G01N 2500/02 (20130101)
G01N 2800/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371994 Heath et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) James R. Heath (Pasadena, California);  Arundhati Nag (Pasadena, California);  Samir Das (Pasadena, California);  Joseph O. Varghese (Pasadena, California);  Ryan K. Henning (Pasadena, California)
ABSTRACT The present application provides stable peptide-based Akt capture agents and methods of use as detection and diagnosis agents and in the treatment of diseases and disorders. The application further provides methods of manufacturing Akt capture agents using iterative on-bead in situ click chemistry.
FILED Friday, September 12, 2014
APPL NO 14/485243
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 7/06 (20130101)
C07K 7/08 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/485 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/574 (20130101)
G01N 33/582 (20130101)
G01N 33/5748 (20130101) Original (OR) Class
G01N 2333/91205 (20130101)
G01N 2440/14 (20130101)
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11372004 Venditti et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Charles P. Venditti (Potomac, Maryland);  Irini Manoli (Bethesda, Maryland)
ABSTRACT Methods of using biomarkers in determining the efficacy of a treatment for an organic acidemia in a subject are disclosed herein. Methods of using biomarkers in determining the efficacy of a liver-directed treatment for an organic acidemia in a subject are likewise disclosed herein.
FILED Thursday, September 06, 2018
APPL NO 16/641994
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/74 (20130101)
G01N 33/5008 (20130101)
G01N 33/6893 (20130101) Original (OR) Class
G01N 2333/50 (20130101)
G01N 2800/04 (20130101)
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11372005 Newman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
APPLICANT(S) MOREHOUSE SCHOOL OF MEDICINE (Atlanta, Georgia)
ASSIGNEE(S) Morehouse School of Medicine (Atlanta, Georgia)
INVENTOR(S) Gale W. Newman (Duluth, Georgia);  James W. Lillard, Jr. (Smyrna, Georgia);  Chamberlain Obialo (Atlanta, Georgia)
ABSTRACT The present application relates to methods of treating HIV-associated nephropathy (HIVAN) and/or focal segmental glomerulosclerosis (FSGS) using endothelin-1 (ET-1) antagonists. The application further relates to a composition for the treatment of HIVAN and/or FSGS. A kit for detecting the presence of ET-1 or ET-1-associated biomarker in a biological sample is also disclosed.
FILED Tuesday, November 10, 2020
APPL NO 17/094175
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 31/40 (20130101)
A61K 31/422 (20130101)
A61K 31/505 (20130101)
A61K 31/506 (20130101)
A61K 31/4025 (20130101)
A61K 38/12 (20130101)
A61K 45/06 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101)
C12Q 2600/106 (20130101)
C12Q 2600/156 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/74 (20130101)
G01N 33/78 (20130101)
G01N 33/6893 (20130101) Original (OR) Class
G01N 33/56988 (20130101)
G01N 2333/5754 (20130101)
G01N 2800/28 (20130101)
G01N 2800/52 (20130101)
G01N 2800/347 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11372069 Griswold et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S) Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S) Mark A. Griswold (Cleveland, Ohio);  Cameron McIntyre (Cleveland, Ohio)
ABSTRACT A method for target identification for a deep brain stimulation procedure includes acquiring a set of magnetic resonance fingerprinting (MRF) data for a region of interest in a subject using a MRI system, comparing the set of MRF data to an MRF dictionary to determine at least one parameter for the MRF data for the region of interest, generating a quantitative map of the at least one parameter, segmenting a target area of the region of interest based on the MRF data, generating at least one trajectory for placement of at least one electrode in the target area of the region of interest based on the segmentation of the target area and displaying the quantitative map and the at least one trajectory on a display.
FILED Monday, November 18, 2019
APPL NO 16/686828
ART UNIT 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/50 (20130101)
G01R 33/4806 (20130101)
G01R 33/5608 (20130101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 2207/10088 (20130101)
G06T 2207/20084 (20130101)
G06T 2207/20112 (20130101)
G06T 2207/30016 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11373066 Lee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Leica Microsystems CMS GmbH (Wetzlar, Germany)
ASSIGNEE(S) Leica Microsystems CMS GmbH (Wetzlar, Germany)
INVENTOR(S) Shih-Jong James Lee (Bellevue, Washington);  Hideki Sasaki (Bellevue, Washington)
ABSTRACT A computerized method of deep model matching for image transformation includes inputting pilot data and pre-trained deep model library into computer memories; performing a model matching scoring using the pilot data and the pre-trained deep model library to generate model matching score; and performing a model matching decision using the model matching score to generate a model matching decision output. Additional pilot data may be used to perform the model matching scoring and the model matching decision iteratively to obtain improved model matching decision output. Alternatively, the pre-trained deep model library may be pre-trained deep adversarial model library in the method.
FILED Friday, May 17, 2019
APPL NO 16/416115
ART UNIT 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00523 (20130101)
G06K 9/00536 (20130101)
G06K 9/627 (20130101) Original (OR) Class

Computer Systems Based on Specific Computational Models
G06N 3/04 (20130101)

Image or Video Recognition or Understanding
G06V 30/194 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11373303 Mauldin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) Rivanna Medical LLC (Charlottesville, Virginia)
ASSIGNEE(S) Rivanna Medical, Inc. (Charlottesville, Virginia)
INVENTOR(S) Frank William Mauldin (Charlottesville, Virginia);  Kevin Owen (Crozet, Virginia)
ABSTRACT In some embodiments, a method comprises: obtaining a 2D ultrasound image of an imaged region of a subject, the imaged region comprising bone; identifying model template cross-sections of a 3D model of the bone corresponding to the 2D image at least in part by registering the 2D ultrasound image to the 3D model, wherein the model template cross-sections are defined prior to obtaining such 2D image, the model template cross-sections having size and shape representative of a population of potential subjects; identifying at least one location of at least one landmark feature of the bone in the 2D image based on results of the registration; and generating a visualization that includes: a visualization of the 2D image and a visualization of one of the identified cross-sections of the 3D model, wherein the visualization indicates the at least one location of the at least one landmark feature.
FILED Sunday, May 03, 2020
APPL NO 16/865372
ART UNIT 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 8/461 (20130101)
A61B 8/0858 (20130101)
A61B 8/0875 (20130101)
A61B 8/5223 (20130101)
A61B 8/5246 (20130101)
A61B 8/5269 (20130101)

Image Data Processing or Generation, in General
G06T 5/009 (20130101)
G06T 7/0012 (20130101) Original (OR) Class
G06T 7/30 (20170101)
G06T 11/60 (20130101)
G06T 15/08 (20130101)
G06T 2200/04 (20130101)
G06T 2207/10132 (20130101)
G06T 2207/30008 (20130101)

Image or Video Recognition or Understanding
G06V 10/42 (20220101)
G06V 10/60 (20220101)
G06V 10/467 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11373452 Neckel
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) Georgetown University (Washington, District of Columbia)
ASSIGNEE(S) Georgetown University (Washington, District of Columbia)
INVENTOR(S) Nathan Neckel (Arlington, Virginia)
ABSTRACT Embodiments of the present systems and methods may provide techniques for analyzing rodent gait that addresses the confound of interdependency of gait variables to provide more accurate and reproducible results. In embodiments, multidimensional analysis of gait in animals, such as rodents, may be performed. For example, in an embodiment, a computer-implemented method of animal gait analysis may comprise capturing data relating to steps taken a plurality of animal test subjects, performing a multidimensional analysis of the captured data to generate data describing a gait of the animal test subjects, and outputting data characterizing the gait of the animal test subjects.
FILED Wednesday, August 07, 2019
APPL NO 16/534010
ART UNIT 2486 — Recording and Compression
CURRENT CPC
Image or Video Recognition or Understanding
G06V 20/653 (20220101)
G06V 40/25 (20220101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11373551 Moore et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Penn State Research Foundation (University Park, Pennsylvania)
ASSIGNEE(S) The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S) Jason Z. Moore (State College, Pennsylvania);  Scarlett Miller (State College, Pennsylvania);  Sven Gunnar Bilen (State College, Pennsylvania);  Joseph Portelli (State College, Pennsylvania)
ABSTRACT A haptic needle insertion simulator includes a syringe compartment having a cavity and a retractable needle at an end of the syringe compartment. The needle is operable to retract into the syringe compartment when pushed against a surface. The cavity is configured to provide a force profile felt by a user holding the simulator and simulating a realistic feeling of insertion force.
FILED Friday, May 10, 2019
APPL NO 17/054307
ART UNIT 3715 — Amusement and Education Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 34/10 (20160201)
A61B 34/30 (20160201)

Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 9/00 (20130101)
G09B 23/30 (20130101)
G09B 23/285 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11373553 Miller et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Penn State Research Foundation (University Park, Pennsylvania)
ASSIGNEE(S) The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S) Scarlett Miller (State College, Pennsylvania);  Jason Z. Moore (State College, Pennsylvania);  David Han (Hummelstown, Pennsylvania);  Katelin Mirkin (Hummelstown, Pennsylvania);  David Pepley (Johnstown, Pennsylvania);  Mary Yovanoff (State College, Pennsylvania);  Inki Kim (Charlottesville, Virginia)
ABSTRACT A haptic robotic training system includes a haptic robot arm, a position tracking system, a scanning surface, a monitor and a computer. The robotic arm includes a haptic feedback system and holds a custom syringe in place. The position tracking system includes a positon tracking probe shaped like an ultrasound probe and a motion tracker. The scanning surface is a soft pad made from a synthetic phantom tissue. A simulation software receives the positioning data for the syringe from the robotic arm, and for the virtual ultrasound probe from the position tracking system and generates a virtual environment which mimics an actual ultrasound image. The user receives a real time feedback in the form of a haptic feel through the robotic arm, a virtual ultrasound image on the screen, and a performance feedback on the simulation software.
FILED Thursday, August 17, 2017
APPL NO 16/326502
ART UNIT 3715 — Amusement and Education Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 34/10 (20160201)
A61B 34/20 (20160201)
A61B 34/35 (20160201)
A61B 34/76 (20160201)
A61B 90/37 (20160201)
A61B 2034/104 (20160201)
A61B 2034/105 (20160201)
A61B 2034/2063 (20160201)
A61B 2090/378 (20160201)

Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 23/286 (20130101) Original (OR) Class
G09B 23/303 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11373672 Mesgarani et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Nima Mesgarani (New York, New York);  Yi Luo (New York, New York);  James O'Sullivan (New York, New York);  Zhuo Chen (New York, New York)
ABSTRACT Disclosed are devices, systems, apparatus, methods, products, and other implementations, including a method comprising obtaining, by a device, a combined sound signal for signals combined from multiple sound sources in an area in which a person is located, and applying, by the device, speech-separation processing (e.g., deep attractor network (DAN) processing, online DAN processing, LSTM-TasNet processing, Conv-TasNet processing), to the combined sound signal from the multiple sound sources to derive a plurality of separated signals that each contains signals corresponding to different groups of the multiple sound sources. The method further includes obtaining, by the device, neural signals for the person, the neural signals being indicative of one or more of the multiple sound sources the person is attentive to, and selecting one of the plurality of separated signals based on the obtained neural signals. The selected signal may then be processed (amplified, attenuated).
FILED Wednesday, October 24, 2018
APPL NO 16/169194
ART UNIT 2655 — Digital Audio Data Processing
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/12 (20130101)
A61B 5/318 (20210101)

Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding
G10L 17/26 (20130101)
G10L 21/0272 (20130101)
G10L 25/30 (20130101) Original (OR) Class
G10L 25/66 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 11369261 Larin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Sea Systems Command (NAVSEA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Human Genome Research Institute (NHGRI)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) University of Houston System (Houston, Texas)
ASSIGNEE(S) UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas)
INVENTOR(S) Kirill V. Larin (Friendswood, Texas);  Jiasong Li (Houston, Texas);  Manmohan Singh (Houston, Texas);  Chen Wu (Houston, Texas);  Salavat Aglyamov (Austin, Texas)
ABSTRACT An excitation force (internal or external) and phase-sensitive optical coherence elastography (OCE) system, used in conjunction with a data analyzing algorithm, is capable of measuring and quantifying biomechanical parameters of tissues in situ and in vivo. The method was approbated and demonstrated on an example of the system that combines a pulsed ultrasound system capable of producing an acoustic radiation force on the crystalline lens surface and a phase-sensitive optical coherence tomography (OCT) system for measuring the lens displacement caused by the acoustic radiation force. The method allows noninvasive and nondestructive quantification of tissue mechanical properties. The noninvasive measurement method also utilizes phase-stabilized swept source optical coherence elastography (PhS-SSOCE) to distinguish between tissue stiffness, such as that attributable to disease, and effects on measured stiffness that result from external factors, such as pressure applied to the tissue. Preferably, the method is used to detect tissue stiffness and to evaluate the presence of its stiffness even if it is affected by other factors such as intraocular pressure (TOP) in the case of cornea, sclera, or the lens. This noninvasive method can evaluate the biomechanical properties of the tissues in vivo for detecting the onset and progression of degenerative or other diseases (such as keratoconus).
FILED Tuesday, September 03, 2019
APPL NO 16/558413
ART UNIT 2872 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 3/16 (20130101)
A61B 3/0025 (20130101) Original (OR) Class
A61B 3/102 (20130101)
A61B 3/165 (20130101)
A61B 5/0051 (20130101)
A61B 5/0053 (20130101)
A61B 5/0066 (20130101)
A61B 5/0093 (20130101)
A61B 5/0097 (20130101)
A61B 8/10 (20130101)
A61B 8/485 (20130101)
A61B 2576/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369596 Trotti et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Thomas Jefferson University (Philadelphia, Pennsylvania)
ASSIGNEE(S) Thomas Jefferson University (Philadelphia, Pennsylvania)
INVENTOR(S) Davide Trotti (Bala Cynwyd, Pennsylvania);  Piera Pasinelli (Bala Cynwyd, Pennsylvania);  Michael R. Jablonski (Philadelphia, Pennsylvania)
ABSTRACT The present invention provides a method of treating or ameliorating a neurodegenerative disease in a mammal, the method comprising administering to the mammal a therapeutically effective amount of a neurodegenerative disease drug, wherein the drug is a substrate of an ABC transporter inhibitor, wherein the mammal is further administered a therapeutically effective amount of an ABC transporter inhibitor, whereby the neurodegenerative disease is treated in the mammal. In certain embodiments, the neurodegenerative disease comprises at least one selected from the group consisting of spinal cord injury, Alzheimer's disease, Parkinson's disease, Huntington's disease, prion disease, amyotrophic lateral sclerosis, a tauopathy, and chronic traumatic encephalopathy.
FILED Thursday, February 28, 2019
APPL NO 16/289273
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/55 (20130101)
A61K 31/55 (20130101)
A61K 31/428 (20130101)
A61K 31/428 (20130101)
A61K 31/473 (20130101) Original (OR) Class
A61K 31/473 (20130101)
A61K 31/496 (20130101)
A61K 31/496 (20130101)
A61K 31/4725 (20130101)
A61K 31/4725 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11370558 Hoffman
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) United States of America as Represented by The Secretary of The Army (Alexandria, Virginia)
ASSIGNEE(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia)
INVENTOR(S) Nolan R Hoffman (Vicksburg, Mississippi)
ABSTRACT In one embodiment, tie-down assembly is provided for securing a parked aircraft to a slab of an aircraft mooring area. The assembly includes a support structure having a first side wall, a second side wall, a first end cover coupled with the first side wall and the second side wall, and a second end cover coupled with the first side wall and the second side wall. The assembly also includes a connector rod coupled with the first side wall and the second side wall, a talon pivot rod coupled with the first side wall and the second side wall, a first talon rotatably coupled with the talon pivot rod, a second talon rotatably coupled with the talon pivot rod, a first depth adjustment mechanism coupled with the first talon, and a second depth adjustment mechanism coupled with the second talon.
FILED Tuesday, January 14, 2020
APPL NO 16/742841
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for
B64F 1/16 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11370828 Westendorf et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Interior (DOI)
Interior Business Center (IBC)
Department of Health and Human Services (HHS)
APPLICANT(S) AbCellera Biologies Inc. (Vancouver, Canada);  The United States of America, as represented by the Secretary, Department of Health and Human Svcs. (Bethesda, Maryland)
ASSIGNEE(S) AbCellera Biologies Inc. (Vancouver, Canada);  The United States of America, as represented by the Secretary, Department of Health and Human Svcs. (Bethesda, Maryland)
INVENTOR(S) Kathryn Westendorf (Vancouver, Canada);  Stefanie Zentelis (Vancouver, Canada);  Krithika Muthuraman (Toronto, Canada);  Kevin Jepson (Vancouver, Canada);  Ester Falconer (Vancouver, Canada);  John Mascola (Bethesda, Maryland);  Barney Graham (Bethesda, Maryland);  Kizzmekia Corbett (Bethesda, Maryland);  Julie Ledgerwood (Bethesda, Maryland);  Lingshu Wang (Bethesda, Maryland);  Olubukola Abiona (Bethesda, Maryland);  Wei Shi (Bethesda, Maryland);  Wing-pui Kong (Bethesda, Maryland);  Yi Zhang (Bethesda, Maryland);  Bryan Edward Jones (San Diego, California);  Denisa Foster (San Diego, California);  Julian Davies (La Jolla, California);  Qing Chai (San Diego, California);  Christopher Carl Frye (Bargersville, Indiana);  Ganapathy Gopalrathnam (Fishers, Indiana);  Jörg Hendle (San Diego, California);  John Michael Sauder (Carlsbad, California);  Jeffrey Streetman Boyles (Indianapolis, Indiana);  Anna Pustilnik (San Diego, California)
ABSTRACT Antibodies that bind SARS-CoV spike protein, SARS-CoV-2 spike protein, and methods of using same for treating or preventing conditions associated with SARS or COVID-19 and for detecting SARS-CoV or SARS-CoV-2.
FILED Tuesday, June 22, 2021
APPL NO 17/354434
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/215 (20130101)
A61K 47/6801 (20170801)
A61K 2039/505 (20130101)

Peptides
C07K 16/10 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5091 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11370887 Wagener et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S) Kenneth B. Wagener (Gainesville, Florida);  Taylor W. Gaines (Chandler, Arizona);  Michael Bell (North East, Maryland);  Julia Grace Pribyl (Gainesville, Florida)
ABSTRACT A polysulfone has sulfone units that are separated by alkylene units in a polymer chain or a copolymer chain where the alkylene units have at least four carbons between sulfone units. The alkylene units can include an ethenylene unit separated from the sulfone units by at least one methylene units. The polysulfones can be crosslinked for enhanced thermal stability. Membranes can be formed from the polysulfones.
FILED Tuesday, January 19, 2021
APPL NO 17/152164
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 75/22 (20130101) Original (OR) Class

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 3/242 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371003 Ma et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Zhenqiang Ma (Middleton, Wisconsin);  Yei Hwan Jung (Madison, Wisconsin);  Michael Phillips (Stoughton, Wisconsin);  David Gamm (Waunakee, Wisconsin);  Shaoqin Gong (Middleton, Wisconsin)
ABSTRACT Photoreceptor scaffolds and scaffold systems including the photoreceptor scaffolds are described herein. The scaffolds and scaffold systems can be used for transplantation of organized photoreceptor tissue, with or without RPE, which may improve grafted cell survival, integration, and functional visual rescue. Particularly, the photoreceptor scaffold is structured from a biocompatible film, patterned with an array of unique through-holes having a curvilinear cell receiver and at least one cell guide channel.
FILED Friday, February 05, 2016
APPL NO 15/016753
ART UNIT 1796 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 21/08 (20130101)
C12M 23/20 (20130101)
C12M 23/26 (20130101)
C12M 23/30 (20130101)
C12M 25/14 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371022 Park et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S) Tae-Eun Park (Boston, Massachusetts);  Anna Herland (Brookline, Massachusetts);  Edward Anthony Fitzgerald (Boston, Massachusetts);  Donald Elliot Ingber (Boston, Massachusetts)
ABSTRACT The invention relates to a method of creating a human blood-brain barrier (BBB) model from the differentiation of human pluripotent stem cells (hPSCs), wherein the BBB exhibits sustained transendothelial electrical resistances (TEER) over 2000 Ω·cm2 for at least 3 days after seeding.
FILED Thursday, February 16, 2017
APPL NO 16/076857
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 23/16 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0062 (20130101)
C12N 5/0068 (20130101)
C12N 5/069 (20130101) Original (OR) Class
C12N 2500/02 (20130101)
C12N 2502/081 (20130101)
C12N 2506/02 (20130101)
C12N 2506/45 (20130101)
C12N 2533/90 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/403 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371079 Medintz et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Igor L. Medintz (Springfield, Virginia);  Mario Ancona (Alexandria, Virginia);  W. Russ Algar (Vancouver, Canada);  Melissa M. Massey (Vancouver, Canada)
ABSTRACT Time-resolved nucleic acids include a long-lifetime FRET donor with an emission lifetime of at least one millisecond (such as a terbium complex), configured as a donor in a first FRET process, and at least one fluorescent dye with an emission lifetime of less than 100 nanoseconds configured as an acceptor in the FRET process. They can be configured as photonic wires, hybridization probes or beacons, and/or systems for computing logical operations.
FILED Tuesday, September 24, 2019
APPL NO 16/580489
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6818 (20130101) Original (OR) Class
C12Q 1/6818 (20130101)
C12Q 2563/107 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371097 Abdulhameed et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) THE GOVERNMENT OF THE UNITED STATES, as represented by THE SECRETARY OF THE ARMY (Fort Detrick, Maryland)
ASSIGNEE(S) The Government of the United States, as represented by the Secretary of the Army (Fort Detrick, Maryland)
INVENTOR(S) Mohamed Diwan M. Abdulhameed (Frederick, Maryland);  Gregory J. Tawa (Doylestown, Pennsylvania);  Danielle L. Ippolito (Frederick, Maryland);  John A. Lewis (Greencastle, Pennsylvania);  Sven Anders Wallqvist (Frederick, Maryland);  Jonathan D. Stallings (Frederick, Maryland);  Matthew G. Permenter (Knoxville, Maryland)
ABSTRACT Disclosed are methods and articles (e.g., gene arrays or antibodies) for determining the progression or regression of liver fibrosis, for the diagnosis of liver disease, and for screening compounds for hepatotoxicity and efficacy against liver fibrosis. Related therapeutic methods also are disclosed.
FILED Friday, January 29, 2016
APPL NO 15/547168
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/68 (20130101)
C12Q 1/6883 (20130101) Original (OR) Class
C12Q 2600/106 (20130101)
C12Q 2600/112 (20130101)
C12Q 2600/118 (20130101)
C12Q 2600/136 (20130101)
C12Q 2600/142 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5014 (20130101)
G01N 33/6893 (20130101)
G01N 2800/56 (20130101)
G01N 2800/085 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371629 Di Carlo et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) The Boeing Company (Chicago, Illinois)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Tony Di Carlo (Long Beach, California);  Brian T. Vaniman (Fountain Valley, California);  John P. Leuer (Newport Beach, California)
ABSTRACT A method of fabricating a conduit comprises steps of attaching a first tubular outboard ply to a first inner collar portion of a first collar with a third weld and attaching the first tubular outboard ply to a second inner collar portion of a second collar with a fifth weld. The method also comprises steps of interconnecting the first inner collar portion and a first outer collar portion of the first collar with a first weld, interconnecting the second inner collar portion and a second outer collar portion of the second collar with a sixth weld, attaching a trimmed first corrugated-inboard-ply end of a corrugated inboard ply to the first outer collar portion with a second weld, attaching a trimmed second corrugated-inboard-ply end of a corrugated inboard ply to the second outer collar portion with a fourth weld, and communicatively coupling a first sensor with an interstitial space.
FILED Wednesday, January 06, 2021
APPL NO 17/143073
ART UNIT 3753 — Fluid Handling and Dispensing
CURRENT CPC
Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General
F16L 5/022 (20130101) Original (OR) Class
F16L 27/111 (20130101)
F16L 2201/30 (20130101)

Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for
G01M 3/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371785 Brown et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Research Laboratory (NRL)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretarv of the Navy (Washington, District of Columbia)
INVENTOR(S) Robert F. Brown (Summerland Key, Florida);  Gregory M. Smith (Alexandria, Virginia);  Christopher Brady (Bradenton, Florida)
ABSTRACT A cooling system for a cold spray nozzle or a thermal spray barrel and a fabrication method thereof are provided. The cooling system includes a sleeve with cooling fins that encapsulate a spray nozzle or barrel to enable heat transfer from the nozzle or barrel to the fins and then to the external ambient environment. The sleeve may optionally include one or more channels with cooling tubes to enable enhanced cooling with a cooling medium flowing through the tubes and across the fins.
FILED Tuesday, June 22, 2021
APPL NO 17/354780
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Spraying Apparatus; Atomising Apparatus; Nozzles
B05B 15/00 (20130101)

Details of Heat-exchange and Heat-transfer Apparatus, of General Application
F28F 1/26 (20130101) Original (OR) Class

Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance
F41A 21/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371819 Runell et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Jason B. Runell (East Stroudsburg, Pennsylvania);  Ricardo Villela (Staten Island, New York);  Niral Patel (Parsippany, New Jersey);  Alan Cohen (Wharton, New Jersey);  Christopher Griffith (East Stroudsburg, Pennsylvania)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Jason B. Runell (East Stroudsburg, Pennsylvania);  Ricardo Villela (Staten Island, New York);  Niral Patel (Parsippany, New Jersey);  Alan Cohen (Wharton, New Jersey);  Christopher Griffith (East Stroudsburg, Pennsylvania)
ABSTRACT A packaging arrangement for 30 mm×173 mm ammunition rounds. The packaging arrangement has a heavy duty standoff device of defined height, which standoff device mounts a very high strength support plate and a heavy duty restraining plate. The support plate has through holes (of diameter slightly less than the rounds defined maximum diameter) to hold the rounds of in an upside down position and from sliding/moving. The height of the standoff device keeps the rounds from being able to touch the bottom of the metal box. The restraining plate has multiple recessed areas sized to accommodate the back ends of the said rounds. The packaging arrangement is lowered into a metal box with handles for carriage purposes. On top, there are Homosite filler pads, and the box accommodates a top lid.
FILED Tuesday, December 18, 2012
APPL NO 13/718271
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages
B65D 25/04 (20130101)
B65D 25/108 (20130101)
B65D 85/30 (20130101)

Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 39/08 (20130101) Original (OR) Class
F42B 39/26 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371916 Kesavan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Aberdeen Proving Ground (APG)
Combat Capabilities Development Command (CCDC)
Chemical Biological Center (CCDC CBC)
APPLICANT(S) Combat Capabilities Development Command, Chemical Biological Center (Apg, Maryland)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Jana S Kesavan (Catonsville, Maryland);  Nathan Kesavan (Catonsville, Maryland);  Jerold R Bottiger (Aberdeen, Maryland)
ABSTRACT An apparatus for passive sampling of airborne particles such as those found in an aerosol is disclosed. The passive sampler is designed to take advantage of natural air flow to collect airborne particles, such as those contained in an aerosol, for subsequent analysis. The passive sampler increases the sampling efficiency for diffusion and electrostatic collection of particles by using natural airflow or movement to bring particles closer to the deposition surface. Alternately charged electret filters further increase the sampling efficiency.
FILED Thursday, September 10, 2020
APPL NO 17/017521
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/2205 (20130101) Original (OR) Class
G01N 1/2273 (20130101)
G01N 2001/2223 (20130101)
G01N 2001/2276 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371937 Diebold et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Eric D. Diebold (Los Angeles, California);  Bahram Jalali (Los Angeles, California);  Brandon Buckley (Los Angeles, California)
ABSTRACT Apparatus and methods for fluorescence imaging using radiofrequency multiplexed excitation. One apparatus splits an excitation laser beam into two arms of a Mach-Zehnder interferometer. The light in the first beam is frequency shifted by an acousto-optic deflector, which is driven by a phase-engineered radiofrequency comb designed to minimize peak-to-average power ratio. This RF comb generates multiple deflected optical beams possessing a range of output angles and frequency shifts. The second beam is shifted in frequency using an acousto-optic frequency shifter. After combining at a second beam splitter, the two beams are focused to a line on the sample using a conventional laser scanning microscope lens system. The acousto-optic deflectors frequency-encode the simultaneous excitation of an entire row of pixels, which enables detection and de-multiplexing of fluorescence images using a single photomultiplier tube and digital phase-coherent signal recovery techniques.
FILED Wednesday, July 31, 2019
APPL NO 16/528463
ART UNIT 2884 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/05 (20130101)
G01N 21/6408 (20130101) Original (OR) Class
G01N 21/6458 (20130101)
G01N 21/6486 (20130101)
G01N 2021/6415 (20130101)
G01N 2021/6419 (20130101)
G01N 2201/06113 (20130101)

Optical Elements, Systems, or Apparatus
G02B 21/16 (20130101)
G02B 21/0076 (20130101)
G02B 21/0084 (20130101)
G02B 27/1006 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/11 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371957 Oja et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
APPLICANT(S) ABBOTT DIABETES CARE INC. (Alameda, California)
ASSIGNEE(S) ABBOTT DIABETES CARE INC. (Alameda, California)
INVENTOR(S) Stephen M. Oja (Alameda, California);  Benjamin Feldman (Alameda, California)
ABSTRACT A method for sensing an analyte utilizing a sensor having a working electrode, the method includes providing the working electrode with an analyte-specific enzyme and a redox mediator, providing the working electrode to the analyte, accumulating charge derived from the analyte reacting with the analyte-specific enzyme and the redox mediator for a set period of time, connecting the working electrode to circuit after the set period of time, and measuring the signal from the accumulated charge.
FILED Friday, June 29, 2018
APPL NO 16/024353
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/002 (20130101)
A61B 5/14532 (20130101)
A61B 5/14865 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/001 (20130101)
C12Q 1/004 (20130101)
C12Q 2527/113 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/3271 (20130101)
G01N 27/3272 (20130101)
G01N 27/3276 (20130101)
G01N 27/3277 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371960 Fu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
ASSIGNEE(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S) Yangyang Fu (East Lansing, Michigan);  Peng Zhang (East Lansing, Michigan);  John P. Verboncoeur (Okemos, Michigan)
ABSTRACT A microscale gas breakdown device includes a first surface and a second surface. The first surface and the second surface define a gap distance. The device includes a perturbation on the first surface or the second surface. The perturbation is defined by a height value and a radius value. The device includes a current source or a voltage source configured to apply a current or a voltage across the first surface and the second surface. In response to the current or the voltage being applied, a resulting discharge travels along a first discharge path in response to being exposed to a high pressure and a second discharge path in response to being exposed to a low pressure.
FILED Friday, July 26, 2019
APPL NO 16/523255
ART UNIT 2879 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/30 (20130101)
G01N 27/70 (20130101) Original (OR) Class

Electric Discharge Tubes or Discharge Lamps
H01J 17/40 (20130101)

Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams
H05H 1/0006 (20130101)
H05H 1/24 (20130101)
H05H 1/0081 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371965 Jauriqui et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Air Force Research Laboratory (AFRL)
Materials and Manufacturing Directorate (MMD)
APPLICANT(S) VIBRANT CORPORATION (Albuquerque, New Mexico)
ASSIGNEE(S) Vibrant Corporation (Albuquerque, New Mexico)
INVENTOR(S) Leanne Jauriqui (Albuquerque, New Mexico);  Thomas Köhler (Diez, Germany);  Alexander J. Mayes (Albuquerque, New Mexico);  Julieanne Heffernan (Albuquerque, New Mexico);  Richard Livings (Albuquerque, New Mexico);  Eric Biedermann (Albuquerque, New Mexico)
ABSTRACT Creation and use of a digital twin instance (DTI) for a physical instance of the part. The DTI may be created by a model inversion process such that model parameters are iterated until a convergence criterion related to a physical resonance inspection result and a digital resonance inspection result is satisfied. The DTI may then be used in relation to part evaluation including through simulated use of the part. The physical instance of the part may be evaluated by way of the DTI or the DTI may be used to generate maintenance schedules specific to the physical instance of the part.
FILED Thursday, July 09, 2020
APPL NO 17/291746
ART UNIT 2851 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 29/04 (20130101)
G01N 29/52 (20130101)
G01N 29/4418 (20130101) Original (OR) Class

Electric Digital Data Processing
G06F 30/13 (20200101)
G06F 30/17 (20200101)
G06F 30/20 (20200101)
G06F 2119/02 (20200101)
G06F 2119/18 (20200101)

Image Data Processing or Generation, in General
G06T 2207/20072 (20130101)
G06T 2207/20076 (20130101)
G06T 2207/20096 (20130101)
G06T 2207/20132 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371966 Jauriqui et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Air Force Research Laboratory (AFRL)
Materials and Manufacturing Directorate (MMD)
APPLICANT(S) Vibrant Corporation (Albuquerque, New Mexico)
ASSIGNEE(S) Vibrant Corporation (Albuquerque, New Mexico)
INVENTOR(S) Leanne Jauriqui (Albuquerque, New Mexico);  Thomas Kohler (Diez, Germany);  Alexander J. Mayes (Albuquerque, New Mexico);  Julieanne Heffernan (Albuquerque, New Mexico);  Richard Livings (Albuquerque, New Mexico);  Eric Biedermann (Albuquerque, New Mexico)
ABSTRACT Creation and use of a digital twin instance (DTI) for a physical instance of the part. The DTI may be created by a model inversion process such that model parameters are iterated until a convergence criterion related to a physical resonance inspection result and a digital resonance inspection result is satisfied. The DTI may then be used in relation to part evaluation including through simulated use of the part. The physical instance of the part may be evaluated by way of the DTI or the DTI may be used to generate maintenance schedules specific to the physical instance of the part.
FILED Wednesday, January 26, 2022
APPL NO 17/585299
ART UNIT 2851 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 29/04 (20130101)
G01N 29/52 (20130101)
G01N 29/4418 (20130101) Original (OR) Class

Electric Digital Data Processing
G06F 30/13 (20200101)
G06F 30/17 (20200101)
G06F 30/20 (20200101)
G06F 30/367 (20200101)
G06F 30/3308 (20200101)
G06F 2119/02 (20200101)
G06F 2119/18 (20200101)

Image Data Processing or Generation, in General
G06T 2207/20072 (20130101)
G06T 2207/20076 (20130101)
G06T 2207/20096 (20130101)
G06T 2207/20132 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371994 Heath et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) James R. Heath (Pasadena, California);  Arundhati Nag (Pasadena, California);  Samir Das (Pasadena, California);  Joseph O. Varghese (Pasadena, California);  Ryan K. Henning (Pasadena, California)
ABSTRACT The present application provides stable peptide-based Akt capture agents and methods of use as detection and diagnosis agents and in the treatment of diseases and disorders. The application further provides methods of manufacturing Akt capture agents using iterative on-bead in situ click chemistry.
FILED Friday, September 12, 2014
APPL NO 14/485243
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 7/06 (20130101)
C07K 7/08 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/485 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/574 (20130101)
G01N 33/582 (20130101)
G01N 33/5748 (20130101) Original (OR) Class
G01N 2333/91205 (20130101)
G01N 2440/14 (20130101)
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11372017 German et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Chemical Biological Center (CCDC CBC)
APPLICANT(S) Charles River Analytics, Inc. (Cambridge, Massachusetts)
ASSIGNEE(S) Charles River Analytics, Inc. (Cambridge, Massachusetts)
INVENTOR(S) Stan German (Cherry Hill, New Jersey);  Michael Kim (Cambridge, Massachusetts);  Henry Roth (Boston, Massachusetts)
ABSTRACT Methods, techniques, apparatus, and algorithms are described for robustly measuring real-world distances using any mobile device equipped with an accelerometer and monocular camera. A general software implementation processes 2D video, precisely tracking points of interest across frames to estimate the unsealed trajectory of the device, which is used to correct the device's inertially derived trajectory. The visual and inertial trajectories are then aligned in scale space to estimate the physical distance travelled by the device and the true distance between the visually tracked points.
FILED Monday, August 24, 2020
APPL NO 17/001120
ART UNIT 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement
G01P 7/00 (20130101) Original (OR) Class
G01P 15/08 (20130101)

Image Data Processing or Generation, in General
G06T 5/006 (20130101)
G06T 7/50 (20170101)
G06T 7/246 (20170101)
G06T 2207/30241 (20130101)

Wireless Communication Networks
H04W 88/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11372019 Krueger et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) Honeywell International Inc. (Morris Plains, New Jersey)
ASSIGNEE(S) Honeywell International Inc. (Charlotte, North Carolina)
INVENTOR(S) Neil Krueger (Saint Paul, Minnesota);  Chad Fertig (Bloomington, Minnesota);  Matthew Puckett (Phoenix, Arizona);  Arthur Savchenko (Kirkland, Washington);  Steven Tin (Plymouth, Minnesota);  Joshua Dorr (Minneapolis, Minnesota)
ABSTRACT An optomechanical device optomechanical device for stabilizing an optomechanical resonator comprising a circuit configured to generate a first optical signal and a second optical signal, modulate the first optical signal, modulate the second optical signal, and combine the first optical signal and the second optical signal into a combined optical signal to direct the combined optical signal into an assembly. An inner sidewall of a first beam structure of the assembly has a first inner spatial frequency correspond to a second inner spatial frequency of an inner sidewall of a second beam structure of the assembly and an outer sidewall of the first beam structure has a first outer spatial frequency correspond to a second outer spatial frequency of an outer sidewall of the second beam structure.
FILED Tuesday, August 13, 2019
APPL NO 16/539949
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Microstructural Devices or Systems, e.g Micromechanical Devices
B81B 3/0067 (20130101)
B81B 3/0083 (20130101)
B81B 7/02 (20130101)
B81B 2201/0235 (20130101)

Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement
G01P 15/093 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11372119 Aull et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Brian F. Aull (Cambridge, Massachusetts);  Joseph S. Ciampi (Westford, Massachusetts);  Renee D. Lambert (Framingham, Massachusetts);  Christopher Leitz (Watertown, Massachusetts);  Karl Alexander McIntosh (Groton, Massachusetts);  Steven Rabe (W. Roxbury, Massachusetts);  Kevin Ryu (Arlington, Massachusetts);  Daniel R. Schuette (Arlington, Massachusetts);  David Volfson (Sharon, Massachusetts)
ABSTRACT A chip-to-chip integration process for rapid prototyping of silicon avalanche photodiode (APD) arrays has been developed. This process has several advantages over wafer-level 3D integration, including: (1) reduced cost per development cycle since a dedicated full-wafer read-out integrated circuit (ROIC) fabrication is not needed, (2) compatibility with ROICs made in previous fabrication runs, and (3) accelerated schedule. The process provides several advantages over previous processes for chip-to-chip integration, including: (1) shorter processing time as the chips can be diced, bump-bonded, and then thinned at the chip-level faster than in a wafer-level back-illumination process, and (2) the CMOS substrate provides mechanical support for the APD device, allowing integration of fast microlenses directly on the APD back surface. This approach yields APDs with low dark count rates (DCRs) and higher radiation tolerance for harsh environments and can be extended to large arrays of APDs.
FILED Friday, January 31, 2020
APPL NO 16/778042
ART UNIT 2896 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Measurement of Nuclear or X-radiation
G01T 1/248 (20130101) Original (OR) Class

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/1464 (20130101)
H01L 27/14609 (20130101)
H01L 27/14634 (20130101)
H01L 27/14643 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11372134 Lentz
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) US Government as rep'ed by Secy of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Joshua Lentz (Niceville, Florida)
ABSTRACT A film includes a substrate having a planar surface attachable to a surface that transmits electromagnetic energy; and a photonic crystal structure formed in the planar substrate that alters the transmitted electromagnetic energy.
FILED Thursday, January 02, 2020
APPL NO 16/732395
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 1/005 (20130101) Original (OR) Class
G02B 5/08 (20130101)
G02B 5/18 (20130101)
G02B 5/205 (20130101)
G02B 5/3083 (20130101)

Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 1/20 (20130101)
H01P 1/222 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11372758 Abed et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) Jackson State University (Jackson, Mississippi)
ASSIGNEE(S) Jackson State University (Jackson, Mississippi)
INVENTOR(S) Khalid Abed (Madison, Mississippi);  Tirumale Ramesh (Chantilly, Virginia)
ABSTRACT Embodiments of a system for dynamic reconfiguration of cache are disclosed. Accordingly, the system includes a plurality of processors and a plurality of memory modules executed by the plurality of processors. The system also includes a dynamic reconfigurable cache comprising of a multi-level cache implementing a combination of an L1 cache, an L2 cache, and an L3 cache. The one or more of the L1 cache, the L2 cache, and the L3 cache are dynamically reconfigurable to one or more sizes based at least in part on an application data size associated with an application being executed by the plurality of processors. In an embodiment, the system includes a reconfiguration control and distribution module configured to perform dynamic reconfiguration of the dynamic reconfigurable cache based on the application data size.
FILED Tuesday, May 12, 2020
APPL NO 16/872409
ART UNIT 2138 — Memory Access and Control
CURRENT CPC
Electric Digital Data Processing
G06F 12/121 (20130101)
G06F 12/0811 (20130101) Original (OR) Class
G06F 2212/1024 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11372821 Ganti et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Raghu Kiran Ganti (Elmsford, New York);  Shen Li (Urbana, Illinois);  Mudhakar Srivatsa (White Plains, New York)
ABSTRACT A spatial-temporal storage method, system, and non-transitory computer readable medium, include, in a first layer, a geometric translation circuit configured to split spatial-temporal information into row keys and translate a geometry query into a range scan, and a multi-scan optimization circuit configured to compute an optimal read strategy to optimize the range scan translated by the geometric translation circuit into a series of block starting offsets and block sizes, and, in a second layer, a block grouping circuit configured to allow grouping of blocks in the second layer while preserving spatial data locality when splits of spatial-temporal information occur in the first layer.
FILED Tuesday, August 07, 2018
APPL NO 16/056672
ART UNIT 2152 — Data Bases & File Management
CURRENT CPC
Electric Digital Data Processing
G06F 16/221 (20190101)
G06F 16/275 (20190101)
G06F 16/284 (20190101)
G06F 16/1844 (20190101) Original (OR) Class
G06F 16/2264 (20190101)
G06F 16/2452 (20190101)
G06F 16/2453 (20190101)
G06F 16/2477 (20190101)
G06F 16/9537 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11372854 Friedman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Smart Information Flow Technologies, LLC (Minneapolis, Minnesota)
ASSIGNEE(S) Smart Information Flow Technologies, LLC (Minneapolis, Minnesota)
INVENTOR(S) Scott Ehrlich Friedman (Minneapolis, Minnesota);  Jeffrey Mathew Rye (Minneapolis, Minnesota);  David Thomas LaVergne (Minneapolis, Minnesota)
ABSTRACT Provenance analysis systems and methods. Datums representing relationships between entities can be stored in a knowledge store. Datums can be received from agents as agents perform activities. Activity records are be stored in a provenance graph, the activity record and associate received datums with any input datums used in the activity. Provenance subgraphs can 5 be retrieved by traversing the provenance graph for selected datums and presented through a user interface. Provenance subgraphs can be augmented with trust modifiers determined based on attributions, confidences, and refutations provided by a user. Trust modifiers can be propagated downstream to enable the addressing of junctions in variable confidence.
FILED Friday, September 11, 2020
APPL NO 16/948297
ART UNIT 2166 — Data Bases & File Management
CURRENT CPC
Electric Digital Data Processing
G06F 16/245 (20190101) Original (OR) Class
G06F 16/252 (20190101)
G06F 16/2379 (20190101)
G06F 21/62 (20130101)

Computer Systems Based on Specific Computational Models
G06N 5/04 (20130101)
G06N 20/00 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11373089 Englund
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Dirk Robert Englund (Brookline, Massachusetts)
ABSTRACT Most artificial neural networks are implemented electronically using graphical processing units to compute products of input signals and predetermined weights. The number of weights scales as the square of the number of neurons in the neural network, causing the power and bandwidth associated with retrieving and distributing the weights in an electronic architecture to scale poorly. Switching from an electronic architecture to an optical architecture for storing and distributing weights alleviates the communications bottleneck and reduces the power per transaction for much better scaling. The weights can be distributed at terabits per second at a power cost of picojoules per bit (versus gigabits per second and femtojoules per bit for electronic architectures). The bandwidth and power advantages are even better when distributing the same weights to many optical neural networks running simultaneously.
FILED Wednesday, February 06, 2019
APPL NO 16/268578
ART UNIT 2123 — AI & Simulation/Modeling
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/04 (20130101)
G06N 3/08 (20130101)
G06N 3/0675 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11373112 Higa et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Information Warfare Center (NIWC)
Naval Information Warfare Center Pacific (NIWCPACIFIC)
APPLICANT(S) Naval Information Warfare Center, Pacific (San Diego, California)
ASSIGNEE(S) United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Brian A. Higa (San Diego, California);  Kenneth S. Simonsen (San Diego, California);  Osama M. Nayfeh (San Diego, California)
ABSTRACT A method useful for network and spectrum defense which operates to analyze cyber data and spectra while performing real time optimization which is based on the analyzed cyber data or spectrum. The method utilizes quantum computing and reconfigurable qubits with built-in memory to sample a target cyber data or spectrum, search through the sample and determine a desired or required network or spectrum reallocation, and determine optimal values for its order parameters and Hamiltonian and tune the qubits in accordance with the determination. An embodiment may provide for spectrum optimization that minimizes frequency bandwidth, power, and bit error rate. The desired or required network or spectrum reallocation and optimal values order parameters and Hamiltonian may be stored in the built-in memory to facilitate machine learning.
FILED Friday, January 24, 2020
APPL NO 16/751339
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Electric Digital Data Processing
G06F 15/7867 (20130101)

Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11373786 Familiant et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Eaton Intelligent Power Limited (Dublin, Ireland)
ASSIGNEE(S) Eaton Intelligent Power Limited (Dublin, Sweden)
INVENTOR(S) Yakov L. Familiant (Thiensville, Wisconsin);  Paul J. Rollmann (Menomonee Falls, Wisconsin);  Andrew A. Rockhill (Waukesha, Wisconsin)
ABSTRACT An apparatus includes a laminated bus bar assembly with first and second bus bars and an intervening insulator layer. A surge arrestor (e.g., a metal oxide varistor) has a body mounted on the bus bar assembly and first and second terminals on first and second opposite sides of the body. In some embodiments, the body may be at least partially disposed in an opening in the first bus bar and the second terminal may be conductively bonded to a surface of the second bus bar that faces the insulator layer. In some embodiments, the second terminal may include a conductive stud passing through an opening in the second bus bar. The apparatus may include a spring clamp attached to the first bus bar and contacting the first side of the body to retain the body.
FILED Monday, August 10, 2020
APPL NO 16/989531
ART UNIT 2848 — Electrical Circuits and Systems
CURRENT CPC
Resistors
H01C 7/12 (20130101) Original (OR) Class

Installation of Electric Cables or Lines, or of Combined Optical and Electric Cables or Lines
H02G 5/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11373833 Hoff et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States of America as represented by the Secretary of the Air Force (Kirtland AFB, New Mexico)
ASSIGNEE(S) Government of the United States, as Represented by the Secretary of the Air Force (Kirtland AFB, New Mexico)
INVENTOR(S) Brad Winston Hoff (Albuquerque, New Mexico);  Wilkin Wai-Hang Tang (Albuquerque, New Mexico);  Sterling Ryan Beeson (Tijeras, New Mexico);  Ali Sayir (Bay Village, Ohio)
ABSTRACT Systems, methods and apparatus related to a method for constructing a field emission device. The method includes providing a metal cathode substrate; shaping a carbon fiber fabric into a pattern, creating a patterned carbon fiber fabric; and brazing at least a portion of the patterned carbon fiber fabric to the metal cathode substrate.
FILED Wednesday, October 02, 2019
APPL NO 16/591030
ART UNIT 2879 — Optics
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 1/304 (20130101)
H01J 9/025 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11374106 Brueck et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) UNM RAINFOREST INNOVATIONS (Albuquerque, New Mexico)
ASSIGNEE(S)
INVENTOR(S) Steven R. J. Brueck (Albuquerque, New Mexico);  Stephen D. Hersee (Albuquerque, New Mexico);  Seung-Chang Lee (Albuquerque, New Mexico);  Daniel Feezell (Albuquerque, New Mexico)
ABSTRACT A method for making a heteroepitaxial layer. The method comprises providing a semiconductor substrate. A seed area delineated with a selective growth mask is formed on the semiconductor substrate. The seed area comprises a first material and has a linear surface dimension of less than 100 nm. A heteroepitaxial layer is grown on the seed area, the heteroepitaxial layer comprising a second material that is different from the first material. Devices made by the method are also disclosed.
FILED Tuesday, January 21, 2020
APPL NO 16/748327
ART UNIT 2897 — Semiconductors/Memory
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 10/00 (20130101)
B82Y 40/00 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/02107 (20130101)
H01L 21/02381 (20130101)
H01L 21/02532 (20130101)
H01L 21/02538 (20130101)
H01L 21/02639 (20130101)
H01L 27/1211 (20130101)
H01L 29/04 (20130101)
H01L 29/16 (20130101)
H01L 29/20 (20130101)
H01L 29/045 (20130101)
H01L 29/0665 (20130101)
H01L 29/0673 (20130101)
H01L 29/0676 (20130101)
H01L 29/775 (20130101)
H01L 29/785 (20130101)
H01L 29/7783 (20130101)
H01L 29/7827 (20130101)
H01L 29/7851 (20130101)
H01L 29/66462 (20130101) Original (OR) Class
H01L 29/66469 (20130101)
H01L 29/66666 (20130101)
H01L 29/66795 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11374133 Han et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) UNM RAINFOREST INNOVATIONS (Albuquerque, New Mexico)
ASSIGNEE(S) UNM RAINFOREST INNOVATIONS (Albuquerque, New Mexico)
INVENTOR(S) Sang M. Han (Albuquerque, New Mexico);  Omar Abudayyeh (Albuquerque, New Mexico);  David Wilt (Albuquerque, New Mexico);  Nathan Gapp (Albuquerque, New Mexico)
ABSTRACT A method for forming electrical contacts for a solar cell and a solar cell formed using the method is provided. The method includes forming a first metal layer over predefined portions of a surface of the solar cell; depositing a carbon nanotube layer over the first metal layer; and forming a second metal layer over the carbon nanotube layer, wherein the first metal layer, the carbon nanotube layer, and the second metal layer form a first metal matrix composite layer that provides electrical conductivity and mechanical support for the metal contacts.
FILED Friday, June 17, 2016
APPL NO 15/737250
ART UNIT 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/05 (20130101)
H01L 31/02008 (20130101) Original (OR) Class

Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules
H02S 40/44 (20141201)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 977/75 (20130101)
Y10S 977/89 (20130101)
Y10S 977/752 (20130101)
Y10S 977/842 (20130101)
Y10S 977/891 (20130101)
Y10S 977/901 (20130101)
Y10S 977/948 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11374188 Korivi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Tuskegee University (Tuskegee, Alabama)
ASSIGNEE(S) Tuskegee University (Tuskegee, Alabama)
INVENTOR(S) Naga Korivi (Tuskegee, Alabama);  Kalyan Das (Tuskegee, Alabama)
ABSTRACT A photovoltaic cell includes a substrate layer, an anode layer on the substrate layer, an active layer on the anode layer, and a cathode layer on the active layer, wherein the active layer comprises a plurality of disparately sized n-type and p-type nano-particles of different semiconductor materials randomly distributed in a conductive polymer blend. The n-type nano-particles can include either ZnO or In2O3 nano-particles, and the p-type nano-particles can include either NiO or La2O3 nano-particles. The conductive polymer blend can include P3HT. The bandgaps of the nano-particles have corresponding energies ranging from the near ultraviolet to the far infrared.
FILED Thursday, December 05, 2019
APPL NO 16/704876
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/0352 (20130101)
H01L 51/0036 (20130101)
H01L 51/0097 (20130101)
H01L 51/426 (20130101) Original (OR) Class

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/549 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 70/50 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11374226 Hopkins et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Brandon James Hopkins (Cambridge, Massachusetts);  Douglas P. Hart (Charlestown, Massachusetts);  Yang Shao-Horn (Newton, Massachusetts)
ABSTRACT Corrosion mitigation in a battery may include displacing a first flowable medium with a second flowable medium along a first electrode to interrupt fluid communication of the first flowable medium with the first electrode—thus interrupting operation of the battery—while a second electrode remains in contact with a flowable medium (e.g., one or more of the first flowable medium or another flowable medium, such as a gel). For example, a membrane (e.g., an underwater oleophobic material) may be disposed between the first electrode and the second electrode. An oil may displace an aqueous electrolyte on a first side of the membrane toward a metallic electrode while the aqueous form of the electrolyte remains in contact with an air electrode on a second side of the separator membrane disposed toward the air electrode.
FILED Wednesday, April 24, 2019
APPL NO 16/393645
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/628 (20130101) Original (OR) Class
H01M 10/054 (20130101)
H01M 12/08 (20130101)
H01M 50/46 (20210101)
H01M 50/60 (20210101)
H01M 50/449 (20210101)
H01M 50/571 (20210101)
H01M 2004/023 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11374376 Keyser et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) US Govt as represented by Secretary of Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Christian Keyser (Shalimar, Florida);  Trevor Courtney (Niceville, Florida)
ABSTRACT A cylindrical electrode module of a fiber optic laser system includes an inner cylinder having an inner repeating pattern of longitudinally-aligned positive and negative electrodes on an outer surface of the inner cylinder. The cylindrical electrode mode includes an outer cylinder that encloses the inner cylinder. The outer cylinder that has an outer repeating pattern of longitudinally-aligned negative and positive electrodes on an inner surface of the inner cylinder that are in corresponding and complementary, parallel alignment with the positive and negative electrodes of the inner repeating pattern on the outer surface of the inner cylinder. The cylindrical electrode module includes an optical fiber having an input end configured to align with and be optically coupled to a high power pump laser. The optical fiber is wrapped around the inner cylinder within the outer cylinder to form a cylindrical fiber assembly. The electrodes are activated to achieve quasi-phase matching.
FILED Thursday, August 06, 2020
APPL NO 16/986408
ART UNIT 2874 — Optics
CURRENT CPC
Manufacture, Shaping, or Supplementary Processes
C03B 2203/16 (20130101)
C03B 2203/42 (20130101)

Optical Elements, Systems, or Apparatus
G02B 6/0005 (20130101)
G02B 6/02328 (20130101)
G02B 6/4296 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/0385 (20130101) Original (OR) Class
H01S 5/1003 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11374654 Morton et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Morton Photonics (West Friendship, Maryland)
ASSIGNEE(S) Morton Photonics Inc (West Friendship, Maryland)
INVENTOR(S) Paul A. Morton (West Friendship, Maryland);  Jacob Khurgin (Pikesville, Maryland)
ABSTRACT High-performance ultra-wideband Phased Array Antennas (PAA) are disclosed, having unique capabilities, enabled through photonic integrated circuits and novel optical architectures. Unique capabilities for PAA systems are enabled by photonic integration and ultra-low-loss waveguides. Novel aspects include optical multiplexing combining wavelength division multiplexing and/or a novel extension to array photodetectors, providing the capability to combine many RF photonic signals with very low loss. Architectures include tunable optical up-conversion and down-conversion systems, moving a chosen frequency band between baseband and a high RF frequency band with high dynamic range. Simultaneous multi-channel RF beamforming is achieved through power combining/splitting of optical signals.
FILED Wednesday, April 07, 2021
APPL NO 17/224580
ART UNIT 2636 — Optical Communications
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 27/00 (20130101)

Antennas, i.e Radio Aerials
H01Q 3/2676 (20130101)

Transmission
H04B 10/40 (20130101)
H04B 10/50 (20130101)
H04B 10/60 (20130101)
H04B 10/66 (20130101)
H04B 10/67 (20130101)
H04B 10/69 (20130101)
H04B 10/516 (20130101)
H04B 10/671 (20130101)
H04B 10/697 (20130101)
H04B 10/6911 (20130101)
H04B 10/6971 (20130101)
H04B 10/6972 (20130101)
H04B 10/6973 (20130101)
H04B 10/25759 (20130101) Original (OR) Class
H04B 2210/006 (20130101)

Selecting
H04Q 5/00 (20130101)
H04Q 11/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11374726 Tian et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) INTELLIGENT FUSION TECHNOLOGY, INC. (Germantown, Maryland)
ASSIGNEE(S) INTELLIGENT FUSION TECHNOLOGY, INC. (Germantown, Maryland)
INVENTOR(S) Xin Tian (Germantown, Maryland);  Genshe Chen (Germantown, Maryland);  Khanh Pham (Kirtland AFB, New Mexico);  Erik Blasch (Arlington, Virginia)
ABSTRACT A method for emulating a communication system with fast changing link condition, applied to a testbed system including an interference emulator, a transmitter, and a receiver, includes: by the transmitter, generating code-word symbols, in an initial symbol sequence, according to information bits; evaluating an interference condition and a time duration for each code-word symbol; reordering the code-word symbols to a reordered symbol sequence based on interference conditions; evaluating a total time duration of code-word symbols under each interference condition; and transmitting the code-word symbols in the reordered symbol sequence. The method also includes: by the interference emulator, obtaining the total time duration of code-word symbols under each interference condition from the transmitter; and providing an emulated interference environment by ordering the time durations of different interference conditions. The start time for transmitting code-word symbols with an interference condition is synchronized with the start time for emulating the interference condition.
FILED Thursday, July 09, 2020
APPL NO 16/924853
ART UNIT 2632 — Digital Communications
CURRENT CPC
Transmission
H04B 17/373 (20150115)
H04B 17/3913 (20150115)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 5/1453 (20130101) Original (OR) Class
H04L 25/0204 (20130101)
H04L 25/03343 (20130101)
H04L 2025/03401 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11374960 Boggs et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Nathaniel Gordon Boggs (New York, New York);  Salvatore J. Stolfo (New York, New York)
ABSTRACT Methods, systems and media for evaluating layered computer security products are provided. In some embodiments, the method comprises: (a) identifying portions of attack data associated with an attack; (b) linking the portions of attack data; (c) testing security products using the linked attack data, at least two of the security products using different portions of the linked attack data; (d) storing the results of the testing; (e) repeating (a)-(d) for multiple attacks; receiving information identifying a subset of the security products from a remote computing device; identifying a first set of detected attacks for each of the plurality of security product using the stored results; determining a number of attacks in a union of each of the first sets of identified attacks; determining a detection rate for the identified security products based on the union and the number of tested attacks; and causing the detection rate to be presented.
FILED Friday, March 13, 2020
APPL NO 16/818583
ART UNIT 2437 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/08 (20130101)
H04L 43/028 (20130101)
H04L 63/1416 (20130101)
H04L 63/1425 (20130101)
H04L 63/1433 (20130101) Original (OR) Class
H04L 63/1491 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11375146 Schultz
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Kenneth Schultz (Lexington, Massachusetts)
ABSTRACT Amplitude-modulated (AM) signals spanning a spatial wide area can be efficiently detected using a slowly scanning optical system. The system decouples the AM carrier from the AM signal bandwidth (or carrier uncertainty), enabling Nyquist sampling of only the information-bearing AM signal (or the known frequency bandwidth). The system includes a staring sensor with N pixels (e.g., N>106) that searches for a sinusoidal frequency of unknown phase and frequency, perhaps constrained to a particular band by a priori information about the signal. Counters in the sensor pixels mix the detected signals with local oscillators to down-convert the signal of interest, e.g., to a baseband frequency. The counters store the down-converted signal for read out at a rate lower than the Nyquist rate of AM signal. The counts can be shifted among pixels synchronously with the optical line-of-sight for scanning operation.
FILED Wednesday, February 26, 2020
APPL NO 16/801276
ART UNIT 2636 — Optical Communications
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/487 (20130101)

Demodulation or Transference of Modulation From One Carrier to Another
H03D 3/007 (20130101)

Transmission
H04B 10/116 (20130101)
H04B 10/613 (20130101)
H04B 10/1141 (20130101)

Pictorial Communication, e.g Television
H04N 5/35554 (20130101)
H04N 5/37455 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 11369897 Bahar et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Xergy Inc (Harrington, Delaware)
ASSIGNEE(S) FFI IONIX IP, INC. (Wilmington, Delaware)
INVENTOR(S) Bamdad Bahar (Georgetown, Delaware);  Luyu Jin (Harbeson, Delaware);  William Parmelee (Seaford, Delaware);  Jacob Zerby (Harbeson, Delaware)
ABSTRACT A water purification system utilizes an ionomer membrane and mild vacuum to draw water from source water through the membrane. A water source may be salt water or a contaminated water source. The water drawn through the membrane passes across the condenser chamber to a condenser surface where it is condensed into purified water. The condenser surface may be metal or any other suitable surface and may be flat or pleated. In addition, the condenser surface may be maintained at a lower temperature than the water on the water source side of the membrane. The ionomer membrane may be configured in a cartridge, a pleated or flat plate configuration. A latent heat loop may be configured to carry the latent heat of vaporization from the condenser back to the water source side of the ionomer membrane. The source water may be heated by a solar water heater.
FILED Monday, February 11, 2019
APPL NO 16/273101
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 25/00 (20130101) Original (OR) Class
B01D 61/00 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/14 (20130101)
C02F 1/26 (20130101)
C02F 1/78 (20130101)
C02F 1/447 (20130101)
C02F 1/4672 (20130101)
C02F 9/00 (20130101)
C02F 2201/009 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369944 Jansone-Popova
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Santa Jansone-Popova (Knoxville, Tennessee)
ABSTRACT An organic polymer composition (OPC) comprising guanidinium-containing A units interconnected with B units of the formula *—Rprivate use character Parenopenst*)r, wherein each asterisk (*) in A units denotes a connection point with an asterisk in B units; R is a hydrocarbon linking group containing at least one carbon atom; r is an integer of 1, 2, or 3; and the composition necessarily includes an anionic species Xm− with a magnitude of charge m of at least 1, wherein the sum of negative charge provided by anionic species Xm− counterbalances the total positive charge provided by the A units. Also described herein is a method for removing one or more oxoanions from an aqueous source by (i) contacting the aqueous source with the above described OPC to result in absorption of the oxoanion into the OPC to produce an oxoanion-containing OPC; and (ii) removing the oxoanion-containing OPC from the aqueous source.
FILED Tuesday, October 22, 2019
APPL NO 16/660142
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/24 (20130101)
B01J 20/262 (20130101) Original (OR) Class
B01J 20/2808 (20130101)
B01J 20/3425 (20130101)

Compositions of Macromolecular Compounds
C08L 79/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369962 Sustarich et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) NATIONAL TECHNOLOGY and ENGINEERING SOLUTIONS OF SANDIA, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions Of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Jess M. Sustarich (San Francisco, California);  Chao Chung Shih (Emeryville, California);  Anup Kumar Singh (Danville, California);  Philip Gach (Kensington, California)
ABSTRACT Disclosed are devices and methods useful for confined-channel digital microfluidics that combine high-throughput droplet generators with digital microfluidic for droplet manipulation. The present disclosure also provides an off-chip sensing system for droplet tracking.
FILED Monday, October 26, 2015
APPL NO 15/521231
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Mixing, e.g Dissolving, Emulsifying, Dispersing
B01F 33/3021 (20220101)
B01F 33/3031 (20220101)
B01F 2101/23 (20220101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/50273 (20130101)
B01L 3/502738 (20130101)
B01L 3/502746 (20130101)
B01L 3/502753 (20130101)
B01L 3/502761 (20130101)
B01L 3/502784 (20130101) Original (OR) Class
B01L 7/00 (20130101)
B01L 2200/10 (20130101)
B01L 2200/0605 (20130101)
B01L 2200/0647 (20130101)
B01L 2200/0652 (20130101)
B01L 2200/0673 (20130101)
B01L 2200/0689 (20130101)
B01L 2300/0867 (20130101)
B01L 2300/0883 (20130101)
B01L 2300/1805 (20130101)
B01L 2400/082 (20130101)
B01L 2400/086 (20130101)
B01L 2400/0415 (20130101)
B01L 2400/0424 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1058 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/1404 (20130101)
G01N 15/1434 (20130101)
G01N 35/08 (20130101)
G01N 2015/149 (20130101)
G01N 2015/1413 (20130101)
G01N 2015/1422 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11370027 Manuel et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
National Energy Technology Laboratory (NETL)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida);  UTBATTELLE, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida);  UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Michele Viola Manuel (Gainesville, Florida);  Hunter B. Henderson (Gainesville, Florida);  Orlando Rios (Oak Ridge, Tennessee);  Gerard M. Ludtka (Oak Ridge, Tennessee)
ABSTRACT Disclosed herein is a method comprising disposing a container containing a metal and/or ferromagnetic solid and abrasive particles in a static magnetic field; where the container is surrounded by an induction coil; activating the induction coil with an electrical current, to heat up the metallic or ferromagnetic solid to form a fluid; generating sonic energy to produce acoustic cavitation and abrasion between the abrasive particles and the container; and producing nanoparticles that comprise elements from the container, the metal and/or the ferromagnetic solid and the abrasive particles. Disclosed herein too is a composition comprising first metal or a first ceramic; and particles comprising carbides and/or nitrides dispersed therein. Disclosed herein too is a composition comprising nanoparticles comprising chromium carbide, iron carbide, nickel carbide, γ-Fe and magnesium nitride.
FILED Friday, November 22, 2019
APPL NO 16/692439
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/00 (20130101)
B22F 1/07 (20220101)
B22F 1/054 (20220101)
B22F 9/04 (20130101)
B22F 9/06 (20130101) Original (OR) Class
B22F 2009/042 (20130101)
B22F 2009/045 (20130101)
B22F 2202/01 (20130101)
B22F 2202/05 (20130101)
B22F 2202/07 (20130101)
B22F 2301/058 (20130101)
B22F 2302/10 (20130101)
B22F 2302/20 (20130101)
B22F 2998/10 (20130101)
B22F 2999/00 (20130101)
B22F 2999/00 (20130101)

Alloys
C22C 1/1084 (20130101)
C22C 1/1084 (20130101)

Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 1/00 (20130101)
C25D 15/00 (20130101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 1/0036 (20130101)
H01F 1/047 (20130101)
H01F 1/442 (20130101)

Electric Heating; Electric Lighting Not Otherwise Provided for
H05B 6/367 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11370173 Kelly et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Brett Kelly (Berkeley, California);  Robert Panas (Dublin, California);  Maxim Shusteff (Piedmont, California);  Christopher Spadaccini (Oakland, California);  Hayden Taylor (Berkeley, California);  Indrasen Bhattacharya (Berkeley, California)
ABSTRACT In one aspect the present disclosure relates to a system for forming a three dimensional (3D) object from a volume of photo-responsive material contained within a material container. A plurality of optical projection subsystems are adapted to be arranged circumferentially around a material container containing the volume of photo-responsive material, and are controlled by a controller. The optical projection subsystems direct optical projections at a plurality of angles θ through the volume of photo-responsive material. The optical projections are further directed about a z axis extending through the volume of photo-responsive material. The plurality of optical subsystems are further controlled by the controller to provide each of the optical projections with a calculated three-dimensional intensity distribution acting over a fixed temporal exposure period, which is sufficient to at least one of cure or remove selected portions of the volume of photo-responsive material, and leave other portions unmodified, to form a desired 3D part.
FILED Thursday, November 21, 2019
APPL NO 16/691053
ART UNIT 1749 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/129 (20170801)
B29C 64/232 (20170801)
B29C 64/241 (20170801)
B29C 64/245 (20170801)
B29C 64/264 (20170801)
B29C 64/277 (20170801)
B29C 64/393 (20170801) Original (OR) Class

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
B33Y 50/02 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11370435 Zhao et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan);  Carnegie Mellon University (Pittsburgh, Pennsylvania)
ASSIGNEE(S) GM Global Technology Operations LLC (Detroit, Michigan);  Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S) Junfeng Zhao (Troy, Michigan);  Chen-Fang Chang (Bloomfield Hills, Michigan);  Bharatkumar Hegde (Bloomfield Hills, Michigan);  Insu Chang (Troy, Michigan);  Ragunathan Rajkumar (Monroeville, Pennsylvania)
ABSTRACT A method for controlling automated driving operations of a vehicle includes determining vehicle origin and destination data, and generating a graphical representation of a road network with multiple candidate routes between the vehicle's origin and destination. Road-level data, including speed, turn angle, and/or gradient data, is received for each candidate route, and respective total energy uses are estimated for the vehicle to traverse across the candidate routes. Multiple candidate driving strategies, each having respective speed and acceleration profiles, are determined for the candidate route with the lowest estimated total energy use. An optimal candidate driving strategy is selected through a cost evaluation of the associated speed and acceleration profiles and forward movement simulations of the vehicle over a prediction horizon. Command signals are transmitted to the vehicle's steering and/or powertrain systems to execute control operations based on the optimal driving strategy and the candidate route with the lowest energy use.
FILED Wednesday, September 04, 2019
APPL NO 16/559738
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit
B60W 10/04 (20130101)
B60W 10/20 (20130101)
B60W 30/18 (20130101) Original (OR) Class
B60W 40/06 (20130101)
B60W 2552/00 (20200201)
B60W 2554/00 (20200201)
B60W 2554/801 (20200201)
B60W 2554/804 (20200201)
B60W 2710/20 (20130101)
B60W 2720/106 (20130101)

Systems for Controlling or Regulating Non-electric Variables
G05D 1/0088 (20130101)
G05D 2201/0213 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11370736 Dub et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Triad National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S) Triad National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Pavel A. Dub (White Rock, New Mexico);  Rami J. Batrice (Los Alamos, New Mexico);  John C. Gordon (White Rock, New Mexico)
ABSTRACT This application is directed to use of transition metal-ligand complexes to hydrogenate fluorinated esters and carboxamides into fluorinated hemiacetals. Methods for synthesis of certain ligands are also provided.
FILED Wednesday, April 01, 2020
APPL NO 16/837698
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 29/145 (20130101)
C07C 41/20 (20130101) Original (OR) Class
C07C 41/26 (20130101)
C07C 41/50 (20130101)
C07C 41/50 (20130101)
C07C 43/317 (20130101)
C07C 43/317 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/5022 (20130101)
C07F 9/5325 (20130101)
C07F 15/0046 (20130101)
C07F 15/0053 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11370889 Guan et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Zhibin Guan (Irvine, California);  William Ogden (Irvine, California)
ABSTRACT The disclosure provides for dynamic thermosetting polymers comprising boroxine crosslinks that exhibit unusual mechanical behavior by being strong, highly malleable, recyclable and fully reprocessable. The disclosure further provides methods of making the thermosetting polymers and applications thereof.
FILED Friday, May 17, 2019
APPL NO 16/416148
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 79/08 (20130101) Original (OR) Class

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 5/3432 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 185/04 (20130101)

Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives
C09J 185/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11370925 Zalich et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S) PPG Industries Ohio, Inc. (Cleveland, Ohio);  The Regents of the University of California (Oakland, California)
ASSIGNEE(S) PPG Industries Ohio, Inc. (Cleveland, Ohio)
INVENTOR(S) Michael A. Zalich (Wexford, Pennsylvania);  Paul H. Berdahl (Walnut Creek, California);  Stuart D. Hellring (Pittsburgh, Pennsylvania);  William H. Retsch, Jr. (Allison Park, Pennsylvania)
ABSTRACT A coating composition includes: (i) a film-forming resin; (ii) an infrared reflective pigment; and (iii) an infrared fluorescent pigment or dye different from the infrared reflective pigment. A multi-layer coating including the coating composition, and a substrate at least partially coated with the coating composition is also disclosed. A method of detecting an article at least partially coated with the coating composition is also disclosed.
FILED Friday, October 28, 2016
APPL NO 16/067537
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Processes for Applying Fluent Materials to Surfaces, in General
B05D 5/063 (20130101)
B05D 7/52 (20130101)
B05D 7/546 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/013 (20180101)
C08K 5/0041 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 5/004 (20130101) Original (OR) Class
C09D 5/22 (20130101)
C09D 7/62 (20180101)
C09D 127/16 (20130101)

Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 11/02 (20130101)
C09K 11/06 (20130101)
C09K 11/55 (20130101)
C09K 11/58 (20130101)
C09K 11/59 (20130101)
C09K 11/592 (20130101)
C09K 11/685 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6428 (20130101)
G01N 2021/6439 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11370927 Sullivan et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Kyle Sullivan (Pleasanton, California);  John M. Densmore (Livermore, California);  Eric Duoss (Dublin, California);  Alexander E. Gash (Brentwood, California);  Joshua Kuntz (Livermore, California);  John Vericella (Oakland, California)
ABSTRACT In one embodiment, a method includes dispersing a plurality of particles in solution to form a dispersion and adding a stabilizing agent to the dispersion in an amount sufficient to cause the dispersion to exhibit one or more predetermined rheological properties. The particles in the dispersion are configured to complete a self-propagating and/or self-sustaining reaction upon initiation thereof. In another embodiment, a method includes depositing a material on a substrate. The material includes: a plurality of particles configured to complete a self-propagating and/or self-sustaining reaction upon initiation thereof, a solvent system, and one or more stabilizing agents.
FILED Tuesday, June 25, 2019
APPL NO 16/452301
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/118 (20170801)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 11/02 (20130101) Original (OR) Class
C09D 11/03 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/24893 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11370988 Ihala Gamaralalage et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee);  University of Tennessee Research Foundation (Knoxville, Tennessee)
INVENTOR(S) Chanaka Kapila Kumara Ihala Gamaralalage (Oak Ridge, Tennessee);  Jun Qu (Oak Ridge, Tennessee)
ABSTRACT A lubricant composition comprising: (i) silver or gold nanoparticles, each of which is encapsulated by a layer of alkylthiol or alkylamine molecules; (ii) palladium or platinum nanoparticles, each of which is encapsulated by a layer of alkylthiol or alkylamine molecules; and (iii) a fluid in which components (i) and (ii) are present. Further described are methods for applying the lubricant composition onto a mechanical device for which lubrication is beneficial, with resulting improvement in friction and wear reduction and/or corrosion inhibition.
FILED Wednesday, May 15, 2019
APPL NO 16/412548
ART UNIT 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)

Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition
C10M 125/04 (20130101) Original (OR) Class
C10M 177/00 (20130101)
C10M 2201/06 (20130101)
C10M 2215/02 (20130101)
C10M 2219/08 (20130101)

Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions
C10N 2010/02 (20130101)
C10N 2010/14 (20130101)
C10N 2010/16 (20130101)
C10N 2020/06 (20130101)
C10N 2020/061 (20200501)
C10N 2030/06 (20130101)
C10N 2030/12 (20130101)
C10N 2060/09 (20200501)
C10N 2060/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371031 Doudna et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jennifer A. Doudna (Berkeley, California);  David Burstein (Berkeley, California);  Janice S. Chen (Berkeley, California);  Lucas B. Harrington (Berkeley, California);  David Paez-Espino (Walnut Creek, California);  Jillian F. Banfield (Berkeley, California)
ABSTRACT Provided are compositions and methods that include one or more of: (1) a “CasZ” protein (also referred to as a CasZ polypeptide), a nucleic acid encoding the CasZ protein, and/or a modified host cell comprising the CasZ protein (and/or a nucleic acid encoding the same); (2) a CasZ guide RNA that binds to and provides sequence specificity to the CasZ protein, a nucleic acid encoding the CasZ guide RNA, and/or a modified host cell comprising the CasZ guide RNA (and/or a nucleic acid encoding the same); and (3) a CasZ transactivating noncoding RNA (trancRNA) (referred to herein as a “CasZ trancRNA”), a nucleic acid encoding the CasZ trancRNA, and/or a modified host cell comprising the CasZ trancRNA (and/or a nucleic acid encoding the same).
FILED Friday, September 25, 2020
APPL NO 17/032521
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 2319/09 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101) Original (OR) Class
C12N 15/11 (20130101)
C12N 15/113 (20130101)
C12N 2310/20 (20170501)
C12N 2800/80 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371062 Doudna et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jennifer A. Doudna (Berkeley, California);  Jillian F. Banfield (Berkeley, California);  David Burstein (Berkeley, California);  Lucas Benjamin Harrington (Berkeley, California)
ABSTRACT The present disclosure provides CasY proteins, nucleic acids encoding the CasY proteins, and modified host cells comprising the CasY proteins and/or nucleic acids encoding same. CasY proteins are useful in a variety of applications, which are provided. The present disclosure provides CasY guide RNAs that bind to and provide sequence specificity to the CasY proteins, nucleic acids encoding the CasY guide RNAs, and modified host cells comprising the CasY guide RNAs and/or nucleic acids encoding same. CasY guide RNAs are useful in a variety of applications, which are provided. The present disclosure provides methods of identifying a CRISPR RNA-guided endonuclease.
FILED Thursday, September 28, 2017
APPL NO 16/335630
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/46 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/113 (20130101)
C12N 15/902 (20130101) Original (OR) Class
C12N 2310/20 (20170501)
C12N 2740/16043 (20130101)
C12N 2750/14143 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371069 Ladisch et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
Office of Science (DOE-SC)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Michael Ralph Ladisch (West Lafayette, Indiana);  Young Mi Kim (Woodbury, Minnesota)
ABSTRACT Disclosed herein are methods for improving ethanol production from biomass sources by blocking cellulose from binding to lignin.
FILED Thursday, July 23, 2020
APPL NO 16/937055
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/02 (20130101)
C12P 19/14 (20130101) Original (OR) Class
C12P 2201/00 (20130101)

Saccharides Obtained From Natural Sources or by Hydrolysis of Naturally Occurring Disaccharides, Oligosaccharides or Polysaccharides
C13K 1/02 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 50/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371152 Han et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Joint Center for Artificial Photosynthesis (JCAP)
APPLICANT(S) The California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Zhiji Han (Pasadena, California);  Ruud Kortlever (Pasadena, California);  Hsiang-Yun Chen (Pasadena, California);  Jonas C. Peters (Pasadena, California);  Theodor Agapie (Pasadena, California);  Jorge A. Rosas Hernandez (Pasadena, California);  Arnaud A. Thevenon (Pasadena, California)
ABSTRACT A CO2 reduction system has a cathode in contact with a catholyte. The cathode includes a selectivity-determining layer on an electron conductor. The selectivity-determining layer includes a selectivity-determining component that includes a substituted heterocycle.
FILED Tuesday, April 10, 2018
APPL NO 15/950150
ART UNIT 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 1/12 (20130101)

Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes
C10G 2/50 (20130101)

Purifying or Modifying the Chemical Composition of Combustible Gases Containing Carbon Monoxide
C10K 3/00 (20130101)

Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 3/25 (20210101) Original (OR) Class
C25B 11/051 (20210101)
C25B 11/057 (20210101)
C25B 11/075 (20210101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371358 Chakrabarti et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
National Energy Technology Laboratory (NETL)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Suryarghya Chakrabarti (Niskayuna, New York);  Jing Li (Niskayuna, New York)
ABSTRACT A turbine damper may be provided that may include an elongated body sized to fit inside a turbine blade, the elongated body elongated along a radial direction of the turbine blade relative to a rotation axis of the turbine blade, and plural dampening masses coupled with the elongated body and disposed at different locations along the radial direction. The plural dampening masses may be one or more of sized to dampen different vibration modes of the turbine blade, or moveable relative to and along the elongated body in the radial direction.
FILED Wednesday, February 19, 2020
APPL NO 16/794732
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/16 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/30 (20130101)
F05D 2260/96 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371494 Saunders et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S) GAS TECHNOLOGY INSTITUTE (Des Plaines, Illinois)
ASSIGNEE(S) GAS TECHNOLOGY INSTITUTE (Des Plaines, Illinois)
INVENTOR(S) Timothy W Saunders (Rancho Palos Verdes, California);  Joseph Caravella (Sherman Oaks, California)
ABSTRACT A pump for transporting particulate material that includes a first conveyor and a second conveyor together defining a passage, wherein a working surface of each of the conveyors are canted with respect to each other. The pump includes an inlet for introducing the particulate material into the passage and an outlet for expelling the particulate material from the passage, wherein the outlet is positioned out of line with the inlet.
FILED Monday, September 30, 2019
APPL NO 16/588028
ART UNIT 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Positive-displacement Machines for Liquids; Pumps
F04B 19/14 (20130101) Original (OR) Class
F04B 19/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371702 Berry et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Jonathan Dwight Berry (Simpsonville, South Carolina);  Michael John Hughes (State College, Pennsylvania)
ABSTRACT An integrated combustor nozzle includes a combustion liner that extends radially between an inner liner segment and an outer liner segment. The combustion liner includes a forward end portion, an aft end portion, a first side wall, and a second side wall. The aft end portion of the combustion liner defines a turbine nozzle. The integrated combustor nozzle further includes an impingement panel having an impingement plate disposed along an exterior surface of one of the inner liner segment or the outer liner segment. The impingement plate defines a plurality of impingement holes that direct coolant in discrete jets towards the exterior surface of the inner liner segment or the outer liner segment. The impingement panel is radially spaced from the exterior surface to form a cooling flow gap therebetween. The impingement panel includes a collection duct that extends from the impingement panel and defines a collection passage.
FILED Monday, August 31, 2020
APPL NO 17/007068
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers
F23R 3/06 (20130101) Original (OR) Class
F23R 3/26 (20130101)
F23R 3/283 (20130101)
F23R 2900/03044 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371887 Wasserman et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas);  National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas);  U.S. DEPARTMENT OF ENERGY (Washington, District of Columbia)
INVENTOR(S) Daniel Wasserman (West Lake Hills, Texas);  Eric A. Shaner (Albuquerque, New Mexico)
ABSTRACT Systems and methods are provided for filtering coherent infrared light from a thermal background for protection of infrared (IR) imaging arrays and detection systems. A Michelson interferometer is used for coherent light filtering. In an implementation, a system includes a fixed mirror, a beam splitter, and a moving mirror which can be controlled translationally, as well as tip/tilt. The Michelson interferometer may be used as an imaging system. For imaging applications, a system may comprise a tunable array of micro-electromechanical systems (MEMS) mirrors. A mid-wave IR interferometer with electronic feedback and MEMS mirror array is provided.
FILED Friday, July 24, 2020
APPL NO 16/937954
ART UNIT 2884 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/021 (20130101)
G01J 3/45 (20130101)
G01J 3/2803 (20130101)
G01J 5/06 (20130101) Original (OR) Class
G01J 5/10 (20130101)
G01J 2003/2813 (20130101)
G01J 2005/106 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371943 Lamberti et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
National Security Complex and PANTEX Plant (Y-12)
NNSA Critical Mission Site
Operated by Consolidated Nuclear Security, LLC at Oak Ridge, TN (CNS)
APPLICANT(S) Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee);  The University of Tennessee Research Foundation (Knoxville, Tennessee)
ASSIGNEE(S) Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee);  The University of Tennessee Research Foundation (Knoxville, Tennessee)
INVENTOR(S) Vincent E. Lamberti (Oak Ridge, Tennessee);  Dayakar Penumadu (Knoxville, Tennessee)
ABSTRACT Distributed fiber optic chemical and radiation sensors formed by coating the fibers with certain types of response materials are provided. For distributed chemical sensors, the coatings are reactive with the targets; the heat absorbed or released during a reaction will cause a local temperature change on the fiber. For distributed radiation sensors, coating a fiber with a scintillator enhances sensitivity toward thermal neutrons, for example, by injecting light into the fiber. The luminescent components in these materials are taken from conjugated polymeric and oligomeric dyes, metal organic frameworks with sorbed dyes, and two-photon-absorbing semiconductors. The compositions may exhibit strong gamma rejection. Other scintillators combining luminescent materials with neutron converters are available. With a multiple-layer coating, it may be possible to identify the presence of both neutrons and gamma rays, for example. Coatings may be applied during manufacture or in the field.
FILED Thursday, October 01, 2020
APPL NO 17/060253
ART UNIT 2874 — Optics
CURRENT CPC
Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials
C03C 25/1065 (20130101)

Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for
G01M 3/047 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/7703 (20130101) Original (OR) Class

Measurement of Nuclear or X-radiation
G01T 3/06 (20130101)

Optical Elements, Systems, or Apparatus
G02B 6/03694 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371949 Reyes
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Karla Rosa Reyes (Livermore, California)
ABSTRACT A system for characterizing thermal properties of thermally anisotropic heterogeneous samples includes a heating element, a first temperature sensing device, a second temperature sensing device, and a computing system. The heating element is positioned at a first location within a sample and heats the sample. The first temperature sensing device outputs data indicative of temperatures of the first location to the computing device. The second temperature sensing device outputs data indicative of temperatures of the second location to the computing device. The computing device computes a thermal conductivity of the sample based upon the temperatures of the first location. The computing device further outputs an indication of a portion of the sample to which the thermal conductivity pertains based upon the second temperatures.
FILED Tuesday, August 04, 2020
APPL NO 16/984894
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 25/18 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371960 Fu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
ASSIGNEE(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S) Yangyang Fu (East Lansing, Michigan);  Peng Zhang (East Lansing, Michigan);  John P. Verboncoeur (Okemos, Michigan)
ABSTRACT A microscale gas breakdown device includes a first surface and a second surface. The first surface and the second surface define a gap distance. The device includes a perturbation on the first surface or the second surface. The perturbation is defined by a height value and a radius value. The device includes a current source or a voltage source configured to apply a current or a voltage across the first surface and the second surface. In response to the current or the voltage being applied, a resulting discharge travels along a first discharge path in response to being exposed to a high pressure and a second discharge path in response to being exposed to a low pressure.
FILED Friday, July 26, 2019
APPL NO 16/523255
ART UNIT 2879 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/30 (20130101)
G01N 27/70 (20130101) Original (OR) Class

Electric Discharge Tubes or Discharge Lamps
H01J 17/40 (20130101)

Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams
H05H 1/0006 (20130101)
H05H 1/24 (20130101)
H05H 1/0081 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11372235 Pascall et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Andrew J. Pascall (Livermore, California);  Kerry G. Krauter (Livermore, California)
ABSTRACT A deformable mirror has a mirror front face and a mirror back exposed surface. An elastomeric support structure is connected to the mirror back exposed surface. The elastomeric support structure includes a multitude of microchannels wherein the microchannels have a closed end located proximate the mirror back exposed surface and an open end located away from the mirror back exposed surface. A fluid pressure source is connected to the open end of the microchannels. A power source and control system are connected to the fluid pressure source.
FILED Thursday, July 25, 2019
APPL NO 16/522261
ART UNIT 2872 — Optics
CURRENT CPC
Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 80/00 (20141201)

Optical Elements, Systems, or Apparatus
G02B 26/0858 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11372629 Meister et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Reservoir Labs, Inc. (New York, New York)
ASSIGNEE(S) Reservoir Labs, Inc. (San Diego, California)
INVENTOR(S) Benoit J. Meister (New York, New York);  Eric Papenhausen (New York, New York)
ABSTRACT A technique for efficient scheduling of operations in a program for parallelized execution thereof using a multi-processor runtime environment having two or more processors includes constraining the type or number of loop optimization transforms that may be explored such that memory and processing capacity available for the scheduling task are not exceeded, while facilitating a tradeoff between memory locality, parallelization, and/or data communication between memory modules of the multi-processor runtime environment.
FILED Monday, April 20, 2020
APPL NO 16/852867
ART UNIT 2192 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 8/41 (20130101) Original (OR) Class

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11373768 Watson et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
APPLICANT(S) BWXT mPower, Inc. (Charlotte, North Carolina)
ASSIGNEE(S) BWXT mPower, Inc. (Charlotte, North Carolina)
INVENTOR(S) Ronald C. Watson (Forest, Virginia);  John D. Malloy, III (Goode, Virginia)
ABSTRACT A nuclear reactor comprises a pressure vessel containing a nuclear reactor core. A reactor core cooling system comprises a standpipe including a plurality of orifices in fluid communication with a refueling water storage tank (RWST) to drain water from the RWST into the standpipe, and an injection line configured to drain water from the standpipe to the pressure vessel. In some embodiments the standpipe is disposed in the RWST, while in other embodiments the standpipe is disposed outside of the RWST and cross-connection pipes connect the plurality of orifices with the RWST. The reactor core cooling system may further comprise a valve configured to control flow through one orifice of the plurality of orifices in fluid communication with the RWST based on water level in the standpipe. The valve may comprise a float valve having its float disposed in the standpipe.
FILED Friday, January 31, 2014
APPL NO 14/169192
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Nuclear Reactors
G21C 15/18 (20130101) Original (OR) Class

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 30/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11374172 Forrest et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
Solid-State Lighting Program (SSL)
APPLICANT(S) Stephen Forrest (Ann Arbor, Michigan);  Richard Lunt (Ann Arbor, Michigan)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan);  The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S) Stephen Forrest (Ann Arbor, Michigan);  Richard Lunt (Ann Arbor, Michigan)
ABSTRACT Methods and systems for organic vapor jet deposition are provided, where an exhaust is disposed between adjacent nozzles. The exhaust may reduce pressure buildup in the nozzles and between the nozzles and the substrate, leading to improved deposition profiles, resolution, and improved nozzle-to-nozzle uniformity. The exhaust may be in fluid communication with an ambient vacuum, or may be directly connected to a vacuum source.
FILED Tuesday, December 21, 2010
APPL NO 12/974070
ART UNIT 1716 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 14/12 (20130101)
C23C 14/24 (20130101)
C23C 16/4412 (20130101)
C23C 16/4551 (20130101)
C23C 16/45561 (20130101)
C23C 16/45563 (20130101)
C23C 16/45574 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 51/0008 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11374215 Yushin et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Sila Nanotechnologies Inc. (Alameda, California)
ASSIGNEE(S) SILA NANOTECHNOLOGIES, INC. (Alameda, California)
INVENTOR(S) Gleb Yushin (Atlanta, Georgia);  Bogdan Zdyrko (Atlanta, Georgia);  Addison Shelton (Atlanta, Georgia);  Eugene Berdichevsky (Alameda, California);  Igor Luzinov (Clemson, South Carolina);  Alexander Jacobs (Oakland, California);  Eerik Hantsoo (Oakland, California);  George Gomes (Alameda, California)
ABSTRACT A battery electrode composition is provided comprising composite particles, with each composite particle comprising active material and a scaffolding matrix. The active material is provided to store and release ions during battery operation. For certain active materials of interest, the storing and releasing of the ions causes a substantial change in volume of the active material. The scaffolding matrix is provided as a porous, electrically-conductive scaffolding matrix within which the active material is disposed. In this way, the scaffolding matrix structurally supports the active material, electrically interconnects the active material, and accommodates the changes in volume of the active material.
FILED Wednesday, February 09, 2022
APPL NO 17/667965
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/13 (20130101)
H01M 4/38 (20130101)
H01M 4/48 (20130101)
H01M 4/139 (20130101)
H01M 4/364 (20130101) Original (OR) Class
H01M 4/366 (20130101)
H01M 4/0402 (20130101)
H01M 4/624 (20130101)
H01M 4/625 (20130101)
H01M 10/052 (20130101)
H01M 10/054 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11374236 Evans et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) ESS TECH, INC. (Portland, Oregon)
ASSIGNEE(S) ESS TECH, INC. (Portland, Oregon)
INVENTOR(S) Craig E. Evans (West Linn, Oregon);  Sean Casey (Portland, Oregon);  Yang Song (West Linn, Oregon)
ABSTRACT A redox flow battery may include: a membrane interposed between a first electrode positioned at a first side of the membrane and a second electrode positioned at a second side of the membrane opposite to the first side; a first flow field plate comprising a plurality of positive flow field ribs, each of the plurality of positive flow field ribs contacting the first electrode at first supporting regions on the first side; and the second electrode, including an electrode spacer positioned between the membrane and a second flow field plate, the electrode spacer comprising a plurality of main ribs, each of the plurality of main ribs contacting the second flow field plate at second supporting regions on the second side, each of the second supporting regions aligned opposite to one of the plurality of first supporting regions. As such, a current density distribution at a plating surface may be reduced.
FILED Monday, May 22, 2017
APPL NO 15/601560
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/8803 (20130101)
H01M 4/8817 (20130101)
H01M 4/8828 (20130101)
H01M 8/20 (20130101)
H01M 8/188 (20130101)
H01M 8/0239 (20130101)
H01M 8/0245 (20130101)
H01M 8/0258 (20130101) Original (OR) Class

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11374269 Tong et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Georgetown University (Washington, District of Columbia)
ASSIGNEE(S) GEORGETOWN UNIVERSITY (Washington, District of Columbia)
INVENTOR(S) YuYe J. Tong (Gaithersburg, Maryland);  Eric G. Sorte (Washington, District of Columbia)
ABSTRACT Provided are batteries and fuel cells incorporating a stripline detector for use in nuclear magnetic resonance (NMR). The stripline batteries and fuel cells can be used for in situ NMR measurement of battery or fuel cell chemistry. Also provided are methods for measuring in situ battery and fuel cell NMR using the stripline batteries and fuel cells of the invention.
FILED Monday, January 11, 2021
APPL NO 17/145482
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 24/088 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/46 (20130101)
G01R 33/3456 (20130101)
G01R 33/3628 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/587 (20130101)
H01M 4/661 (20130101)
H01M 4/5825 (20130101)
H01M 8/04305 (20130101)
H01M 10/48 (20130101) Original (OR) Class
H01M 10/0525 (20130101)
H01M 50/411 (20210101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11374346 Martinez
FUNDED BY
Department of Energy (DOE)
Office of Environmental Management (DOE-EM)
Savannah River National Laboratory (SRNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Savannah River Nuclear Solutions, LLC (SRNS) at Aiken, SC
APPLICANT(S) SAVANNAH RIVER NUCLEAR SOLUTIONS, LLC (Aiken, South Carolina)
ASSIGNEE(S) Savannah River Nuclear Solutions, LLC (Aiken, South Carolina)
INVENTOR(S) David K. Martinez (Harlem, Georgia)
ABSTRACT A high-voltage self-aligning push to mate electrical interconnect device is provided. The electrical interconnect device includes a housing with a mating end and a receiving end. The interconnect also includes an insulator bushing configured to be affixed to the receiving end of the housing. The interconnect also includes a center pin disposed within the housing. The center pin extends from the mating end of the housing to the receiving end of the housing. The interconnect also includes a connector socket disposed within the insulator bushing and which is in electrical communication with the center pin. The interconnect also includes an alignment sleeve including a chamfered mating funnel defining a void configured to accept and surround the housing and at least a portion of insulator bushing.
FILED Wednesday, June 10, 2020
APPL NO 16/897735
ART UNIT 2833 — Electrical Circuits and Systems
CURRENT CPC
Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors
H01R 13/53 (20130101)
H01R 13/506 (20130101) Original (OR) Class
H01R 13/6278 (20130101)

Installation of Electric Cables or Lines, or of Combined Optical and Electric Cables or Lines
H02G 15/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11374378 Feigenbaum et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California);  Mikhail A. Noginov (Norfolk, Virginia)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California);  Board of Visitors of Norfolk State University (Norfolk, Virginia)
INVENTOR(S) Eyal Feigenbaum (Livermore, California);  Graham S. Allen (Pleasanton, California);  Jay W. Dawson (Livermore, California);  Mikhail A. Noginov (Norfolk, Virginia)
ABSTRACT The present disclosure relates to an optical waveguide system. The system has a first waveguide having a core-guide and a cladding material portion surrounding and encasing the core-guide to form a substantially D-shaped cross sectional profile with an exposed flat section running along a length thereof. The core-guide enables a core-guide mode for an optical pulse signal having a first characteristic, travelling through the core-guide. A material layer of non-linear material is used which forms a second waveguide. The material layer is disposed on the exposed flat section of the cladding material portion. The material layer forms a plasmonic device to achieve a desired coupling with the core-guide to couple optical energy travelling through the core-guide into the material layer to modify the optical energy travelling through the core-guide such that the optical energy travelling through the core-guide has a second characteristic different from the first characteristic.
FILED Friday, August 21, 2020
APPL NO 16/999714
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/1226 (20130101)
G02B 6/02061 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/0941 (20130101)
H01S 3/06725 (20130101)
H01S 3/094019 (20130101)
H01S 3/094076 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11374409 Genc et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Savant Technologies LLC (East Cleveland, Ohio)
ASSIGNEE(S) Savant Technologies LLC (East Cleveland, Ohio)
INVENTOR(S) Sahika Genc (Niskayuna, New York);  Deepak Aravind (Karnataka, India);  Yan Pan (Niskayuna, New York);  Naresh Acharya (Niskayuna, New York);  Chaitanya Ashok Baone (Glenville, New York)
ABSTRACT The example embodiments are directed to a system and method for forecasting load flexibility of a power grid. In one example, the method includes receiving temperature values associated with temperature set points of a plurality of loads that are included on a power grid, forecasting a flexibility of the plurality of loads using a polynomial-time mixed-integer non-linear programming (MINLP) optimization based on the received temperature values for the plurality of loads, and outputting information about the forecasted flexibility for display to a display device. The MINLP optimization performs the forecasting of the load flexibility on a fine-grained basis in comparison to conventional methods and is still fast enough that it can be computed in real-time.
FILED Monday, April 03, 2017
APPL NO 15/477696
ART UNIT 2116 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 17/02 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 3/003 (20200101)
H02J 3/14 (20130101) Original (OR) Class
H02J 3/381 (20130101)

Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications
Y02B 70/3225 (20130101)

Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids
Y04S 20/222 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11374502 Feng et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) Philip X. L. Feng (Cleveland, Ohio);  Shiquan Fan (Cleveland, Ohio);  Liuming Zhao (Cleveland, Ohio);  Ran Wei (Cleveland, Ohio);  Zenghui Wang (Cleveland, Ohio);  Xu-Qian Zheng (Cleveland, Ohio)
ABSTRACT A system includes a rectifier having an input configured to receive a variable AC input voltage and convert the AC input voltage to a rectified output voltage. A power converter has an input coupled to receive the rectified output voltage and to provide a DC supply voltage at an output thereof. A low drop-out regulator has an input coupled to receive the supply voltage and is configured provide a regulated voltage. A sensor is coupled to receive the regulated voltage as a power source and is configured to sense a condition and provide sensor data indicative of the sensed condition.
FILED Monday, April 02, 2018
APPL NO 16/497670
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 7/219 (20130101) Original (OR) Class
H02M 7/2195 (20210501)

Electric Machines Not Otherwise Provided for
H02N 2/00 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/12 (20130101)

Wireless Communication Networks
H04W 4/38 (20180201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11374503 Burkes et al.
FUNDED BY
Department of Energy (DOE)
Office of Environmental Management (DOE-EM)
Savannah River National Laboratory (SRNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Savannah River Nuclear Solutions, LLC (SRNS) at Aiken, SC
APPLICANT(S) SAVANNAH RIVER NUCLEAR SOLUTIONS, LLC (Aiken, South Carolina)
ASSIGNEE(S) Savannah River Nuclear Solutions, LLC (Aiken, South Carolina);  Clemson University (Clemson, South Carolina)
INVENTOR(S) Klaehn W. Burkes (Wagener, Georgia);  Vincent J. Ceyssens (Augusta, Georgia);  Johan H. R. Enslin (Charleston, South Carolina);  Moazzam Nazir (Charleston, South Carolina)
ABSTRACT A power transmission system can include a transformer and compensator circuit(s), each coupled between a node of the transformer and a ground connection. The compensator circuit(s) can each be configured to counteract a DC signal component of an AC signal at the transformer. The compensator circuit(s) can include a converter circuit having an AC side and a DC side and configured to convert a DC voltage on the DC side to an AC signal at the AC side. The compensator circuit(s) can include a DC link coupled to the DC side of the converter circuit. The compensator circuit(s) can include a controller configured to measure a DC signal component between the load and the ground; to determine, based at least in part on the DC signal component, a compensating signal configured to counteract the DC signal component; and to inject, by the converter circuit, the compensating signal to counteract the DC signal component.
FILED Tuesday, March 09, 2021
APPL NO 17/196152
ART UNIT 2836 — Electrical Circuits and Systems
CURRENT CPC
Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 7/537 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 11369267 Melodia et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Northeastern University (Boston, Massachusetts)
ASSIGNEE(S) Northeastern University (Boston, Massachusetts)
INVENTOR(S) Tommaso Melodia (Newton, Massachusetts);  Raffaele Guida (Boston, Massachusetts);  Giuseppe Enrico Santagati (Cambridge, Massachusetts)
ABSTRACT A reconfigurable implantable system for ultrasonic power control and telemetry includes a charging device that includes an ultrasonic transducer to transmit and receive ultrasonic signals transmitted through a biological body, and a signal generator to drive the ultrasonic transducer to transmit an ultrasonic charging signal through the biological body. The system further includes an implantable device configured to communicate wirelessly with the charging device through the biological body via an ultrasonic communication link between the implantable device and the charging device. An implantable ultrasonic transducer receives the ultrasonic charging signal from the charging device and transmits ultrasonic signals through the biological body. A power unit coupled to the ultrasonic transducer harvests energy from the received ultrasonic charging signal when the implantable device is in an energy harvesting mode. A communication unit is configured to switch the implantable device between the energy harvesting mode and an ultrasonic communication mode, and to read data from the sensing or actuation unit and transmit the data through the implantable ultrasonic transducer when the implantable device is in the ultrasonic communication mode.
FILED Tuesday, October 31, 2017
APPL NO 16/345156
ART UNIT 3799 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0015 (20130101)
A61B 5/0028 (20130101)
A61B 5/0031 (20130101) Original (OR) Class
A61B 5/7225 (20130101)
A61B 2560/0219 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/3787 (20130101)

Transmission Systems for Measured Values, Control or Similar Signals
G08C 23/02 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 7/025 (20130101)
H02J 50/15 (20160201)
H02J 50/80 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369381 Zayed et al.
FUNDED BY
Department of Veterans Affairs (DVA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) Washington University (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Mohamed Zayed (St. Louis, Missouri);  Dillon Williams (St. Louis, Missouri);  Guy Genin (St. Louis, Missouri);  Eric Leuthardt (St. Louis, Missouri)
ABSTRACT An arteriovenous graft and methods of reducing the risk of graft thrombosis and extending patency of the arteriovenous graft are provided herein. The arteriovenous graft is operable for attaching to a vein at a venous anastomosis. In some aspects, the arteriovenous graft includes a plurality of grooves at a venous anastomosis end of the arteriovenous graft and the venous anastomoses may be arranged such that the arteriovenous graft and the vein meet at an angle of 30° or less.
FILED Thursday, July 02, 2020
APPL NO 16/920221
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/11 (20130101) Original (OR) Class
A61B 2017/1107 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369399 Bagwell et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) Actuated Medical, Inc. (Bellefonte, Pennsylvania)
ASSIGNEE(S) Actuated Medical, Inc. (Bellefonte, Pennsylvania)
INVENTOR(S) Roger B Bagwell (Bellefonte, Pennsylvania);  Timothy J Higgins (Mingoville, Pennsylvania);  Eric J Hopkins (Bellefonte, Pennsylvania);  Casey A Scruggs (Bellefonte, Pennsylvania);  Kevin A Snook (State College, Pennsylvania)
ABSTRACT A device for engaging tissue includes a body disposable around the distal end of a medical instrument, such as an endoscope, and a handpiece. The body includes a primary channel for receiving the medical instrument and at least one arm channel for receiving an arm therethrough. At least one arm extends through the arm channel of the body and proximally to the handpiece. The arm includes an engagement member distally of the body, and may further include a bend between the body and engagement member. The engagement member is movable between a first position not contacting tissue and a second position contacting tissue. With multiple engagement members, the engagement members are farther apart from one another in the first position and closer together in the second position. Movement of the engagement members is controlled by selective and independent movement of the corresponding arms by rotational and/or translational motion.
FILED Friday, July 13, 2018
APPL NO 16/034965
ART UNIT 3795 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 1/0014 (20130101)
A61B 1/015 (20130101)
A61B 1/00087 (20130101)
A61B 1/00089 (20130101)
A61B 1/00094 (20130101)
A61B 17/30 (20130101) Original (OR) Class
A61B 17/0218 (20130101)
A61B 2017/00269 (20130101)
A61B 2017/00296 (20130101)
A61B 2017/305 (20130101)
A61B 2017/00367 (20130101)
A61B 2017/00477 (20130101)
A61B 2017/00818 (20130101)
A61B 2017/2901 (20130101)
A61B 2017/2926 (20130101)
A61B 2217/005 (20130101)
A61B 2217/007 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369449 Nelson et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) NUtech Ventures (Lincoln, Nebraska)
ASSIGNEE(S) BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska)
INVENTOR(S) Carl A. Nelson (Lincoln, Nebraska);  Nicholas Nelson (Portland, Oregon)
ABSTRACT A surgical robot can be configured for minimally invasive surgery (MIS) and other types of surgery with modular link geometry and disposable components. In some examples, the surgical robot includes a cable driver comprising at least one drive motor configured for tensioning a cable. The surgical robot includes an articulated surgical tool coupled to the drive motor by the cable. The articulated surgical tool comprises at least first and second articulated links and a joint coupling the first and second articulated links. The cable passes through the joint, and the joint comprises an elastic antagonist biased in opposition to tension from the cable to allow bidirectional actuation of the joint. The surgical robot includes a safety lock configured to lock the joint from allowing articulation of the first and second articulated links in response to a loss of tension in the cable.
FILED Friday, September 20, 2019
APPL NO 16/577230
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 1/00149 (20130101)
A61B 34/30 (20160201)
A61B 34/71 (20160201) Original (OR) Class
A61B 2034/715 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369503 Wu et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Shang-Li Wu (Albany, California);  Homayoon Kazerooni (Berkeley, California)
ABSTRACT Systems, methods, and apparatus provide artificial knees. Artificial knees include a thigh link configured to move in unison with a thigh of the person, a shank link configured to be rotatably coupled to the thigh link, and a compression spring rotatably coupled to the thigh link and coupled to a second end of shank link with a second end of the compression spring. During a first range of motion, the compression spring is configured to provide an extension torque between the thigh link and the shank link causing the artificial knee to resist flexion. After the first range of motion, the compression spring is configured to provide a flexion torque between the thigh link and the shank link encouraging the artificial knee to flex resulting in toe clearance during the swing phase. During the swing phase, the compression spring provides no torque between the thigh link and the shank link.
FILED Tuesday, November 26, 2019
APPL NO 16/696872
ART UNIT 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/70 (20130101)
A61F 2/644 (20130101)
A61F 5/0123 (20130101)
A61F 5/0125 (20130101) Original (OR) Class
A61F 2002/503 (20130101)
A61F 2002/5018 (20130101)
A61F 2002/5033 (20130101)
A61F 2002/5072 (20130101)
A61F 2002/5075 (20130101)
A61F 2002/5079 (20130101)
A61F 2005/0141 (20130101)
A61F 2005/0144 (20130101)
A61F 2005/0158 (20130101)
A61F 2005/0169 (20130101)
A61F 2005/0179 (20130101)

Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body
A61H 2205/102 (20130101)

Manipulators; Chambers Provided With Manipulation Devices
B25J 9/0006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369768 Galbraith et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
Small Business Administration (SBA)
Small Business Technology Transfer (STTR)
APPLICANT(S) Separation Design Group IP Holdings, LLC (Waynesburg, Pennsylvania)
ASSIGNEE(S) SEPARATION DESIGN GROUP IP HOLDINGS, LLC (Waynesburg, Pennsylvania)
INVENTOR(S) Stephen Douglas Galbraith (Waynesburg, Pennsylvania);  Kenneth J. McGowan (Waynesburg, Pennsylvania);  Evonne A. Baldauff (Waynesburg, Pennsylvania);  Elise N. Depetris (Waynesburg, Pennsylvania);  David K. Walker (Waynesburg, Pennsylvania)
ABSTRACT Lightweight, portable oxygen concentrators that operate using an ultra rapid, sub one second, adsorption cycle based on advanced molecular sieve materials are disclosed. The amount of sieve material utilized is a fraction of that used in conventional portable devices. This dramatically reduces the volume, weight, and cost of the device. Innovations in valve configuration, moisture control, case and battery design, and replaceable sieve module are described. Patients with breathing disorders and others requiring medical oxygen are provided with a long lasting, low cost alternative to existing portable oxygen supply devices.
FILED Friday, November 08, 2019
APPL NO 16/678018
ART UNIT 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 16/0003 (20140204)
A61M 16/20 (20130101)
A61M 16/0063 (20140204)
A61M 16/101 (20140204) Original (OR) Class
A61M 16/105 (20130101)
A61M 16/107 (20140204)
A61M 16/0666 (20130101)
A61M 16/0672 (20140204)
A61M 16/0875 (20130101)
A61M 16/1005 (20140204)
A61M 2016/1025 (20130101)
A61M 2202/0208 (20130101)
A61M 2205/02 (20130101)
A61M 2205/42 (20130101)
A61M 2205/75 (20130101)
A61M 2205/3327 (20130101)
A61M 2205/3334 (20130101)
A61M 2205/8206 (20130101)

Separation
B01D 53/02 (20130101)
B01D 53/26 (20130101)
B01D 53/0415 (20130101)
B01D 53/0473 (20130101)
B01D 2253/108 (20130101)
B01D 2253/304 (20130101)
B01D 2256/12 (20130101)
B01D 2257/102 (20130101)
B01D 2259/4533 (20130101)
B01D 2259/4541 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 137/85938 (20150401)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11370027 Manuel et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
National Energy Technology Laboratory (NETL)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida);  UTBATTELLE, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida);  UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Michele Viola Manuel (Gainesville, Florida);  Hunter B. Henderson (Gainesville, Florida);  Orlando Rios (Oak Ridge, Tennessee);  Gerard M. Ludtka (Oak Ridge, Tennessee)
ABSTRACT Disclosed herein is a method comprising disposing a container containing a metal and/or ferromagnetic solid and abrasive particles in a static magnetic field; where the container is surrounded by an induction coil; activating the induction coil with an electrical current, to heat up the metallic or ferromagnetic solid to form a fluid; generating sonic energy to produce acoustic cavitation and abrasion between the abrasive particles and the container; and producing nanoparticles that comprise elements from the container, the metal and/or the ferromagnetic solid and the abrasive particles. Disclosed herein too is a composition comprising first metal or a first ceramic; and particles comprising carbides and/or nitrides dispersed therein. Disclosed herein too is a composition comprising nanoparticles comprising chromium carbide, iron carbide, nickel carbide, γ-Fe and magnesium nitride.
FILED Friday, November 22, 2019
APPL NO 16/692439
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/00 (20130101)
B22F 1/07 (20220101)
B22F 1/054 (20220101)
B22F 9/04 (20130101)
B22F 9/06 (20130101) Original (OR) Class
B22F 2009/042 (20130101)
B22F 2009/045 (20130101)
B22F 2202/01 (20130101)
B22F 2202/05 (20130101)
B22F 2202/07 (20130101)
B22F 2301/058 (20130101)
B22F 2302/10 (20130101)
B22F 2302/20 (20130101)
B22F 2998/10 (20130101)
B22F 2999/00 (20130101)
B22F 2999/00 (20130101)

Alloys
C22C 1/1084 (20130101)
C22C 1/1084 (20130101)

Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 1/00 (20130101)
C25D 15/00 (20130101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 1/0036 (20130101)
H01F 1/047 (20130101)
H01F 1/442 (20130101)

Electric Heating; Electric Lighting Not Otherwise Provided for
H05B 6/367 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11370757 Michael et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Katja Michael (El Paso, Texas);  Chunqlang Li (El Paso, Texas);  Thomas Boland (El Paso, Texas);  Hector P. Del Castillo (El Paso, Texas);  Binata Joddar (El Paso, Texas);  Alfredo Ornelas Sanchez (El Paso, Texas);  Javier Hernandez Ortega (El Paso, Texas);  Irodiel Vinales Lozano (El Paso, Texas);  Philip T. Baily (El Paso, Texas)
ABSTRACT Crosslinkers of an amide or thiocarbamate of 7-nitroindoline were prepared with at least two attached reactive groups for crosslinking capability. The photo-cleavability of the invented crosslinkers is based on the known photolysis behavior of N-acyl-7-nitroindolines, and the photolysis behavior of amides and thiocarbamates of 7-nitroindolines. These crosslinkers enable crosslinking of biopolymers, which can be reversed by illumination with light.
FILED Monday, October 19, 2020
APPL NO 17/074232
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 209/08 (20130101) Original (OR) Class
C07D 403/12 (20130101)
C07D 405/12 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 15/26 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11370896 Odent et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Cornell University (Ithaca, New York);  Université de Mons (Mons, Belgium)
ASSIGNEE(S) CORNELL UNIVERSITY (Ithaca, New York);  UNIVERSITÉ DE MONS (Mons, Belgium)
INVENTOR(S) Jérémy Odent (Rebaix, Belgium);  Emmanuel P. Giannelis (Ithaca, New York);  Jean-Marie Raquez (Mons, Belgium);  Philippe Dubois (Braives, Belgium)
ABSTRACT An ionic nanocomposite comprising a nanomaterial comprising charged groups disposed on at least a portion of a surface of the nanomaterial and a polymer material comprising charged pendant group and/or end functionalized charged groups, where the charged groups of the nanomaterial and the charged pendant groups of the polymer material have opposite charges and the nanomaterial and polymer material are connected by one or more ionic bonds. A nanomaterial can be nanoparticles comprising sulfate groups disposed on at least a portion of the surface of the nanoparticles. The polymer material can be a polymer with pendant imidazolium groups. An ionic nanocomposite can be present as a film (e.g., a thin film). An ionic nanocomposite can be used in devices. A nanocomposite can be used in various coating application.
FILED Tuesday, September 12, 2017
APPL NO 16/332296
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 31/00 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 5/18 (20130101)
C08J 2367/04 (20130101)
C08J 2375/04 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/36 (20130101) Original (OR) Class
C08K 9/04 (20130101)
C08K 9/06 (20130101)
C08K 9/06 (20130101)
C08K 9/06 (20130101)
C08K 2201/001 (20130101)
C08K 2201/011 (20130101)

Compositions of Macromolecular Compounds
C08L 67/04 (20130101)
C08L 67/04 (20130101)
C08L 75/04 (20130101)
C08L 75/08 (20130101)
C08L 2201/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371021 Lipke et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Auburn University (Auburn, Alabama)
ASSIGNEE(S) Auburn University (Auburn, Alabama)
INVENTOR(S) Elizabeth A. Lipke (Auburn, Alabama);  Petra Kerscher (Auburn, Alabama);  Alexander J. Hodge (Auburn, Alabama)
ABSTRACT The present invention relates to the production of cell cultures and tissues from undifferentiated pluripotent stem cells using three-dimensional biomimetic materials. The resultant cell cultures or tissues can be used in any of a number of protocols including testing chemicals, compounds, and drugs. Further, the methods and compositions of the present invention further provide viable cell sources and novel cell delivery platforms that allow for replacement of diseased tissue and engraftment of new cardiomyocytes from a readily available in vitro source. The present invention includes novel methods required for the successful production of cell cultures and tissues, systems and components used for the same, and methods of using the resultant cell and tissue compositions.
FILED Thursday, May 23, 2019
APPL NO 16/420714
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0657 (20130101) Original (OR) Class
C12N 5/0696 (20130101)
C12N 2500/46 (20130101)
C12N 2500/50 (20130101)
C12N 2501/999 (20130101)
C12N 2506/45 (20130101)
C12N 2513/00 (20130101)
C12N 2533/52 (20130101)
C12N 2533/54 (20130101)
C12N 2537/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371031 Doudna et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jennifer A. Doudna (Berkeley, California);  David Burstein (Berkeley, California);  Janice S. Chen (Berkeley, California);  Lucas B. Harrington (Berkeley, California);  David Paez-Espino (Walnut Creek, California);  Jillian F. Banfield (Berkeley, California)
ABSTRACT Provided are compositions and methods that include one or more of: (1) a “CasZ” protein (also referred to as a CasZ polypeptide), a nucleic acid encoding the CasZ protein, and/or a modified host cell comprising the CasZ protein (and/or a nucleic acid encoding the same); (2) a CasZ guide RNA that binds to and provides sequence specificity to the CasZ protein, a nucleic acid encoding the CasZ guide RNA, and/or a modified host cell comprising the CasZ guide RNA (and/or a nucleic acid encoding the same); and (3) a CasZ transactivating noncoding RNA (trancRNA) (referred to herein as a “CasZ trancRNA”), a nucleic acid encoding the CasZ trancRNA, and/or a modified host cell comprising the CasZ trancRNA (and/or a nucleic acid encoding the same).
FILED Friday, September 25, 2020
APPL NO 17/032521
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 2319/09 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101) Original (OR) Class
C12N 15/11 (20130101)
C12N 15/113 (20130101)
C12N 2310/20 (20170501)
C12N 2800/80 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371062 Doudna et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jennifer A. Doudna (Berkeley, California);  Jillian F. Banfield (Berkeley, California);  David Burstein (Berkeley, California);  Lucas Benjamin Harrington (Berkeley, California)
ABSTRACT The present disclosure provides CasY proteins, nucleic acids encoding the CasY proteins, and modified host cells comprising the CasY proteins and/or nucleic acids encoding same. CasY proteins are useful in a variety of applications, which are provided. The present disclosure provides CasY guide RNAs that bind to and provide sequence specificity to the CasY proteins, nucleic acids encoding the CasY guide RNAs, and modified host cells comprising the CasY guide RNAs and/or nucleic acids encoding same. CasY guide RNAs are useful in a variety of applications, which are provided. The present disclosure provides methods of identifying a CRISPR RNA-guided endonuclease.
FILED Thursday, September 28, 2017
APPL NO 16/335630
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/46 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/113 (20130101)
C12N 15/902 (20130101) Original (OR) Class
C12N 2310/20 (20170501)
C12N 2740/16043 (20130101)
C12N 2750/14143 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371736 Rackes et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Drexel University (Philadelphia, Pennsylvania)
ASSIGNEE(S) Drexel University (Philadelphia, Pennsylvania)
INVENTOR(S) Adams Edwin Rackes (Philadelphia, Pennsylvania);  Michael Shannon Waring (Philadelphia, Pennsylvania);  Tom Ben David (Philadelphia, Pennsylvania)
ABSTRACT The framework herein may be called outcome-based ventilation (OBV) for evaluating ventilation rates (VR) in commercial buildings and using a system to make informed control decisions based on the resultant indoor air quality (IAQ) and energy consumption outcomes. A ventilation control system includes a ventilation system that provides air circulation to a building and a controller that controls the ventilation system based on input that include a current ventilation rate. The system also includes an optimization system that drives the controller based on factors like building and pollution transport models, scientific estimates of ventilation impacts on productivity, sick leave, and health, user preference parameters, and weather, pollution, and price forecasts.
FILED Wednesday, October 11, 2017
APPL NO 15/730515
ART UNIT 2115 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening
F24F 11/0001 (20130101)
F24F 11/47 (20180101) Original (OR) Class
F24F 11/74 (20180101)
F24F 11/76 (20180101)
F24F 13/28 (20130101)
F24F 2110/10 (20180101)
F24F 2110/30 (20180101)
F24F 2110/66 (20180101)
F24F 2110/70 (20180101)
F24F 2110/74 (20180101)
F24F 2120/14 (20180101)
F24F 2130/10 (20180101)

Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 2219/2614 (20130101)
G05B 2219/2642 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11372038 Yao et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) University of Tennessee Research Foundation (Knoxville, Tennessee)
ASSIGNEE(S) University of Tennessee Research Foundation (Knoxville, Tennessee);  UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Wenxuan Yao (Knoxville, Tennessee);  Jiecheng Zhao (Knoxville, Tennessee);  Yi Cui (Knoxville, Tennessee);  Yilu Liu (Knoxville, Tennessee);  Thomas J. King (Knoxville, Tennessee)
ABSTRACT A system and methods for monitoring an impact of geomagnetic disturbances (GMDs) or an E3 component of electromagnetic pulses (EMP-E3), involving a transducer generating a transduced signal in response to a magnetic field of a current carrying element of a transmission line. The transduced signal reflects harmonic characteristics of the current carrying element, and is amplified and filtered, then digitally converted. Excessive impact is detected when a threshold condition is met with respect to a total harmonic distortion (THD) and/or a change in THD. The THD can be calculated from amplitudes of harmonic components of interest. The amplitudes can be calculated in various ways, including Fourier transforming the digital signal to locate peaks in the resulting spectral lines, or using a phase sensitive detection algorithm in which the digital signal is multiplied by a phase swept reference signal and then integrated.
FILED Friday, November 11, 2016
APPL NO 15/349779
ART UNIT 2865 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/001 (20130101) Original (OR) Class
G01R 31/085 (20130101)
G01R 33/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11372063 Mandal et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) Soumyajit Mandal (Shaker Heights, Ohio);  David Ariando (Cleveland, Ohio);  Mason Greer (Cleveland Heights, Ohio);  Cheng Chen (Cleveland, Ohio)
ABSTRACT An example multi-channel magnetic resonance (MR) system is described. The system includes a plurality of radio frequency (RF) coils and a plurality of spectrometer transceiver channels. Each of the channels including a spectrometer coupled a respective set of the RF coils. The spectrometer is configured to transmit RF signals to excite respective RF coils and to receive MR sensor signals from the excited respective RF coils responsive to excitation thereof. The spectrometer is configured to perform MR spectrometry to provide MR measurement data based on the received MR sensor signals for the respective channel. A synchronization module is coupled to the spectrometer of the respective channel. The synchronization module is configured to synchronize the spectrometer of the respective channel with spectrometers in other channels via a communication link.
FILED Thursday, December 17, 2020
APPL NO 17/125563
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/543 (20130101)
G01R 33/3607 (20130101)
G01R 33/3621 (20130101)
G01R 33/3635 (20130101)
G01R 33/5608 (20130101)
G01R 33/34092 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11372823 Dayan et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) Niv Dayan (Somerville, Massachusetts);  Stratos Idreos (Somerville, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Niv Dayan (Somerville, Massachusetts);  Stratos Idreos (Somerville, Massachusetts)
ABSTRACT Embodiments of the present invention provide a new multi-level data structure, log-structured merge bush (LSM-bush), to alleviate the performance compromise between LSH-table and LSM-tree data structures. Similar to LSM-tree, LSM-bush may buffer writes in memory, merge the writes as sorted runs across multiple levels in storage, and use in-memory fence pointers and Bloom filters to facilitate lookups. LSM-bush differs from LSM-tree in that it allows newer data to be merged more “lazily” than LSM-tree. This can be achieved by allowing larger numbers of runs to be collected at the smaller levels before merging them.
FILED Monday, January 27, 2020
APPL NO 16/773049
ART UNIT 2159 — Data Bases & File Management
CURRENT CPC
Electric Digital Data Processing
G06F 7/14 (20130101)
G06F 16/13 (20190101)
G06F 16/185 (20190101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11373278 Menon et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) University of Utah Research Foundation (Salt Lake City, Utah)
ASSIGNEE(S) University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S) Rajesh Menon (Salt Lake City, Utah);  Ganghun Kim (Salt Lake City, Utah);  Kyle Isaacson (Salt Lake City, Utah)
ABSTRACT Technology is described for methods and systems for imaging an object (110). The method can include an image sensor (116) exposed to light (114) from an object (110) without passing the light through an image modification element. Light intensity of the light (114) can be stored as data in a medium. The image data can be analyzed at a processor (902) as a reconstructed image of the object (110).
FILED Monday, October 02, 2017
APPL NO 16/338687
ART UNIT 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image Data Processing or Generation, in General
G06T 5/003 (20130101) Original (OR) Class
G06T 5/50 (20130101)

Pictorial Communication, e.g Television
H04N 5/232 (20130101)
H04N 5/2171 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11373303 Mauldin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) Rivanna Medical LLC (Charlottesville, Virginia)
ASSIGNEE(S) Rivanna Medical, Inc. (Charlottesville, Virginia)
INVENTOR(S) Frank William Mauldin (Charlottesville, Virginia);  Kevin Owen (Crozet, Virginia)
ABSTRACT In some embodiments, a method comprises: obtaining a 2D ultrasound image of an imaged region of a subject, the imaged region comprising bone; identifying model template cross-sections of a 3D model of the bone corresponding to the 2D image at least in part by registering the 2D ultrasound image to the 3D model, wherein the model template cross-sections are defined prior to obtaining such 2D image, the model template cross-sections having size and shape representative of a population of potential subjects; identifying at least one location of at least one landmark feature of the bone in the 2D image based on results of the registration; and generating a visualization that includes: a visualization of the 2D image and a visualization of one of the identified cross-sections of the 3D model, wherein the visualization indicates the at least one location of the at least one landmark feature.
FILED Sunday, May 03, 2020
APPL NO 16/865372
ART UNIT 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 8/461 (20130101)
A61B 8/0858 (20130101)
A61B 8/0875 (20130101)
A61B 8/5223 (20130101)
A61B 8/5246 (20130101)
A61B 8/5269 (20130101)

Image Data Processing or Generation, in General
G06T 5/009 (20130101)
G06T 7/0012 (20130101) Original (OR) Class
G06T 7/30 (20170101)
G06T 11/60 (20130101)
G06T 15/08 (20130101)
G06T 2200/04 (20130101)
G06T 2207/10132 (20130101)
G06T 2207/30008 (20130101)

Image or Video Recognition or Understanding
G06V 10/42 (20220101)
G06V 10/60 (20220101)
G06V 10/467 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11373552 Magsood et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Virginia Commonwealth University (Richmond, Virginia)
ASSIGNEE(S) VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia)
INVENTOR(S) Hamzah Magsood (Henrico, Virginia);  Ciro H. Alcoba Serrate (Richmond, Virginia);  Ahmed A. El-Gendy (Richmond, Virginia);  Ravi L. Hadimani (Glen Allen, Virginia)
ABSTRACT Anatomically accurate brain phantoms are disclosed which may be patient specific and used for experimentally testing neuromodulation and neuroimaging procedures.
FILED Friday, August 17, 2018
APPL NO 16/104217
ART UNIT 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 31/06 (20130101)
A61L 31/06 (20130101)
A61L 31/024 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 2/006 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 33/3842 (20130101)
B29C 39/003 (20130101)
B29C 64/10 (20170801)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2083/00 (20130101)
B29K 2105/167 (20130101)
B29K 2507/04 (20130101)

Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles
B29L 2031/40 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 80/00 (20141201)

Compositions of Macromolecular Compounds
C08L 83/04 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/58 (20130101)
G01R 33/56341 (20130101)

Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 23/30 (20130101)
G09B 23/286 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11373672 Mesgarani et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Nima Mesgarani (New York, New York);  Yi Luo (New York, New York);  James O'Sullivan (New York, New York);  Zhuo Chen (New York, New York)
ABSTRACT Disclosed are devices, systems, apparatus, methods, products, and other implementations, including a method comprising obtaining, by a device, a combined sound signal for signals combined from multiple sound sources in an area in which a person is located, and applying, by the device, speech-separation processing (e.g., deep attractor network (DAN) processing, online DAN processing, LSTM-TasNet processing, Conv-TasNet processing), to the combined sound signal from the multiple sound sources to derive a plurality of separated signals that each contains signals corresponding to different groups of the multiple sound sources. The method further includes obtaining, by the device, neural signals for the person, the neural signals being indicative of one or more of the multiple sound sources the person is attentive to, and selecting one of the plurality of separated signals based on the obtained neural signals. The selected signal may then be processed (amplified, attenuated).
FILED Wednesday, October 24, 2018
APPL NO 16/169194
ART UNIT 2655 — Digital Audio Data Processing
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/12 (20130101)
A61B 5/318 (20210101)

Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding
G10L 17/26 (20130101)
G10L 21/0272 (20130101)
G10L 25/30 (20130101) Original (OR) Class
G10L 25/66 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11374106 Brueck et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) UNM RAINFOREST INNOVATIONS (Albuquerque, New Mexico)
ASSIGNEE(S)
INVENTOR(S) Steven R. J. Brueck (Albuquerque, New Mexico);  Stephen D. Hersee (Albuquerque, New Mexico);  Seung-Chang Lee (Albuquerque, New Mexico);  Daniel Feezell (Albuquerque, New Mexico)
ABSTRACT A method for making a heteroepitaxial layer. The method comprises providing a semiconductor substrate. A seed area delineated with a selective growth mask is formed on the semiconductor substrate. The seed area comprises a first material and has a linear surface dimension of less than 100 nm. A heteroepitaxial layer is grown on the seed area, the heteroepitaxial layer comprising a second material that is different from the first material. Devices made by the method are also disclosed.
FILED Tuesday, January 21, 2020
APPL NO 16/748327
ART UNIT 2897 — Semiconductors/Memory
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 10/00 (20130101)
B82Y 40/00 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/02107 (20130101)
H01L 21/02381 (20130101)
H01L 21/02532 (20130101)
H01L 21/02538 (20130101)
H01L 21/02639 (20130101)
H01L 27/1211 (20130101)
H01L 29/04 (20130101)
H01L 29/16 (20130101)
H01L 29/20 (20130101)
H01L 29/045 (20130101)
H01L 29/0665 (20130101)
H01L 29/0673 (20130101)
H01L 29/0676 (20130101)
H01L 29/775 (20130101)
H01L 29/785 (20130101)
H01L 29/7783 (20130101)
H01L 29/7827 (20130101)
H01L 29/7851 (20130101)
H01L 29/66462 (20130101) Original (OR) Class
H01L 29/66469 (20130101)
H01L 29/66666 (20130101)
H01L 29/66795 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11374599 Haque et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Tanbir Haque (Jackson Heights, New York);  Peter R. Kinget (Summit, New Jersey);  Matthew W. Bajor (Bayonne, New Jersey)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Tanbir Haque (Jackson Heights, New York);  Peter R. Kinget (Summit, New Jersey);  Matthew W. Bajor (Bayonne, New Jersey)
ABSTRACT Circuits for identifying interferers using compressed-sampling, comprising: a low noise amplifier (LNA); a passive mixer having a first input coupled to an output of the LNA; a local oscillator (LO) source having an output coupled to a second input of the passive mixer; a low pass filter having an input coupled to an output of the passive mixer; an analog-to-digital converter (ADC) having an input coupled to the output of the low pass filter; a digital baseband (DBB) circuit having an input coupled to an output of the ADC; and a compression-sampling digital-signal-processor (DSP) having an input coupled to the output of the DBB circuit, wherein the compression-sampling DSP is configured to output identifiers of frequency locations of interferers, wherein, in a first mode, the LO source outputs a modulated LO signal that is formed by modulating an LO signal with a pseudo-random sequence.
FILED Monday, October 23, 2017
APPL NO 16/331086
ART UNIT 2636 — Optical Communications
CURRENT CPC
Transmission
H04B 1/10 (20130101) Original (OR) Class
H04B 1/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11374658 Melodia et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Northeastern University (Boston, Massachusetts)
ASSIGNEE(S) NORTHEASTERN UNIVERSITY (Boston, Massachusetts)
INVENTOR(S) Tommaso Melodia (Newton, Massachusetts);  Emrecan Demirors (Boston, Massachusetts)
ABSTRACT Embodiments disclosed herein may be implemented in the form of a method or corresponding apparatus for receiving or transmitting network communications carried at acoustic wavelengths via an acoustic medium. The corresponding method or apparatus may include a gate-level digital hardware module communicatively coupled to a communications module and define therein logic blocks configured to perform respective primitive processing functions, sequences of the logic blocks being capable of processing data units in accordance with any of the multiple communications protocols on a data unit-by-data unit basis without reconfiguring. According to some embodiments, the gate-level digital hardware module may be configured to process a data unit in accordance with a first communications protocol by directing the data unit through a first sequence of logic blocks, and process a subsequent data unit in accordance with a second communications protocol by directing the subsequent data unit through a second of sequence logic blocks.
FILED Monday, June 29, 2020
APPL NO 16/915563
ART UNIT 2416 — Multiplex and VoIP
CURRENT CPC
Transmission
H04B 11/00 (20130101) Original (OR) Class
H04B 13/02 (20130101)
H04B 14/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11374736 Gao
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Mathematical Sciences (DMS)
APPLICANT(S) Clemson University (Clemson, South Carolina)
ASSIGNEE(S) Clemson University (Clemson, South Carolina)
INVENTOR(S) Shuhong Gao (Clemson, South Carolina)
ABSTRACT This is a system and method for homomorphic encryption comprising: a key generation module configured to generate a secret key, a public key and a bootstrapping key; a private-key encryption module configured to generate a first ciphertext using the secret key; a public-key encryption module configured to generate a second cyphertext using the public key; a private-key decoding module configured to decode a first ciphertext, a second ciphertext and an encrypted analytic result; a homomorphic computational module configured to perform an analytical operation, according to an analytical operation request on the first ciphertext and the second ciphertext without decrypting the first ciphertext and the second ciphertext using the bootstrapping key; and, wherein the encrypted analytical result is provided by the homomorphic computational module and are encrypted with the secret key.
FILED Thursday, June 20, 2019
APPL NO 16/447831
ART UNIT 2435 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/008 (20130101) Original (OR) Class
H04L 9/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11374774 Parhi et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Keshab K. Parhi (Minneapolis, Minnesota);  S. V. Sandeep Avvaru (Minneapolis, Minnesota)
ABSTRACT An apparatus includes a first feed-forward PUF, a second feed-forward PUF and an exclusive-or circuit configured to perform an exclusive-or operation of an output of the first feed-forward PUF and an output of the second feed-forward PUF.
FILED Tuesday, April 28, 2020
APPL NO 16/860612
ART UNIT 2491 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/3278 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 11369280 Wang et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Lihong Wang (Arcadia, California);  Xiaoming Wei (Guangzhou, China PRC)
ABSTRACT Among the various aspects of the present disclosure is the provision of systems and methods of velocity-matched ultrasonic tagging in photoacoustic flowgraphy.
FILED Monday, March 02, 2020
APPL NO 16/806796
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0051 (20130101)
A61B 5/0095 (20130101)
A61B 5/0285 (20130101) Original (OR) Class
A61B 5/418 (20130101)
A61B 90/92 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371430 Lents et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Glenn Research Center (GLENN)
APPLICANT(S) Raytheon Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S) Raytheon Technologies Corporation (Farmington, Connecticut)
INVENTOR(S) Charles E. Lents (Amston, Connecticut);  Jonathan Rheaume (West Hartford, Connecticut)
ABSTRACT A gas turbine engine includes a compressor section having a first compressor and a second compressor and a turbine section having a first turbine and a second turbine. The first compressor is connected to the first turbine via a first shaft and the second compressor is connected to the second turbine via a second shaft. A motor connected to the first shaft such that rotational energy generated by the motor is translated to the first shaft. A power distribution system connects the motor to a stored power system including at least one of an energy storage unit and a supplementary power unit. The power distribution system is configured to provide power from the stored power system to the motor.
FILED Friday, July 01, 2016
APPL NO 15/200240
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 27/10 (20130101)
B64D 27/24 (20130101)
B64D 41/00 (20130101)
B64D 2221/00 (20130101)

Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 15/10 (20130101)

Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 3/22 (20130101)
F02C 3/24 (20130101)
F02C 6/14 (20130101) Original (OR) Class
F02C 7/32 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/76 (20130101)
F05D 2260/42 (20130101)
F05D 2260/85 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371431 Dyson, Jr.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S)
INVENTOR(S) Rodger W. Dyson, Jr. (Elyria, Ohio)
ABSTRACT A thermal management system for an aircraft is provided that includes thermo-acoustic engines that remove and capture waste heat from the aircraft engines, heat pumps powered by the acoustic waves generated from the waste heat that remove and capture electrical component waste heat from electrical components in the aircraft, and hollow tubes disposed in the aircraft configured to propagate mechanical energy to locations throughout the aircraft and to transfer the electrical component waste heat back to the aircraft engines to reduce overall aircraft mass and improve propulsive efficiency.
FILED Friday, December 13, 2019
APPL NO 16/714131
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 27/12 (20130101)
B64D 27/24 (20130101)
B64D 2027/026 (20130101)

Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 6/18 (20130101) Original (OR) Class
F02C 6/20 (20130101)

Hot Gas or Combustion-product Positive-displacement Engine Plants; Use of Waste Heat of Combustion Engines; Not Otherwise Provided for
F02G 5/02 (20130101)
F02G 2243/54 (20130101)
F02G 2254/15 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/76 (20130101)
F05D 2220/323 (20130101)
F05D 2260/208 (20130101)
F05D 2260/213 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11373264 Juarez et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINSTRATOR OF NASA (Washington, District of Columbia)
INVENTOR(S) Peter D. Juarez (Hampton, Virginia);  Elizabeth D. Gregory (Hampton, Virginia);  K. Elliott Cramer (Yorktown, Virginia)
ABSTRACT A method of detecting defects in a composite structure includes applying heat to a surface of a composite structure. Thermographic images or frames captured by a moving camera may be utilized to corm temporally aligned images that include temperature data (pixels) from a plurality of frames, wherein the pixels comprise data captured at a simple (uniform) time delay from the time at which heat was applied. The temporally aligned thermographic data for the surface region may include variations due to differences in thermal transients caused by defects in the composite structure. The variations in the thermographic data may be utilized to detect one or more defects in the composite structure.
FILED Monday, December 14, 2020
APPL NO 17/121264
ART UNIT 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 70/54 (20130101)
B29C 70/384 (20130101)

Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 5/10 (20130101)
G01J 5/48 (20130101)
G01J 2005/0077 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/8851 (20130101)

Image Data Processing or Generation, in General
G06T 1/0014 (20130101) Original (OR) Class
G06T 7/90 (20170101)
G06T 2207/10048 (20130101)
G06T 2207/30124 (20130101)

Pictorial Communication, e.g Television
H04N 5/33 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11374187 Zeller et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) Magnolia Optical Technologies, Inc. (Woburn, Massachusetts)
ASSIGNEE(S) Magnolia Optical Technologies, Inc. (Woburn, Massachusetts)
INVENTOR(S) John W. Zeller (Woburn, Massachusetts);  Yash R. Puri (Loudonville, New York);  Ashok K. Sood (Brookline, Massachusetts)
ABSTRACT Through selective incorporation of high carrier mobility graphene monolayers into low cost, NIR-sensitive SiGe detector layer structures, a device combining beneficial features from both technologies can be achieved. The SiGe in such hybrid SiGe/graphene detector devices serves as the NIR absorbing layer, or as the quantum dot material in certain device iterations. The bandgap of this SiGe layer where absorption of photons and photogeneration of carriers mainly takes place may be tuned by varying the concentrations of Ge in the SixGe1-x material. This bandgap and the thickness of this layer largely impact the degree and spectral characteristics of absorption properties, and thus the quantum efficiency or responsivity of the device. The main function and utility of the graphene monolayers, which are nearly transparent to incident light, is to facilitate the extraction and transport of electron and hole carriers from the SiGe absorbing layer through the device.
FILED Wednesday, April 22, 2020
APPL NO 16/855982
ART UNIT 2818 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 51/0045 (20130101)
H01L 51/4233 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 11369700 Frank et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) IsoTherapeutics Group, LLC (Angleton, Texas)
ASSIGNEE(S) IGL Pharma Inc. (Angleton, Texas)
INVENTOR(S) R. Keith Frank (Lake Jackson, Texas);  Jaime Simon (Angleton, Texas);  Kelli R. Jay (Brazoria, Texas)
ABSTRACT This invention relates to a Kit formulation to prepare a radioactive, bone-seeking, pharmaceutical drug that has high radiochemical purity (RCP) in a fast, facile and reproducible process. The Kit has at least two vials and a two-part buffer system with instructions on how to make the drug formulation in a radiopharmacy. The drug formulations of this invention can be conveniently and reproducibly prepared with better delivery of the drug to mammals, better radiochemical purity of the formulation for use in treating a mammal having bone pain, one or more calcific tumors or needing bone marrow suppression or bone marrow ablation.
FILED Monday, May 04, 2020
APPL NO 16/866001
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/19 (20130101)
A61K 47/02 (20130101)
A61K 51/0482 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11369768 Galbraith et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
Small Business Administration (SBA)
Small Business Technology Transfer (STTR)
APPLICANT(S) Separation Design Group IP Holdings, LLC (Waynesburg, Pennsylvania)
ASSIGNEE(S) SEPARATION DESIGN GROUP IP HOLDINGS, LLC (Waynesburg, Pennsylvania)
INVENTOR(S) Stephen Douglas Galbraith (Waynesburg, Pennsylvania);  Kenneth J. McGowan (Waynesburg, Pennsylvania);  Evonne A. Baldauff (Waynesburg, Pennsylvania);  Elise N. Depetris (Waynesburg, Pennsylvania);  David K. Walker (Waynesburg, Pennsylvania)
ABSTRACT Lightweight, portable oxygen concentrators that operate using an ultra rapid, sub one second, adsorption cycle based on advanced molecular sieve materials are disclosed. The amount of sieve material utilized is a fraction of that used in conventional portable devices. This dramatically reduces the volume, weight, and cost of the device. Innovations in valve configuration, moisture control, case and battery design, and replaceable sieve module are described. Patients with breathing disorders and others requiring medical oxygen are provided with a long lasting, low cost alternative to existing portable oxygen supply devices.
FILED Friday, November 08, 2019
APPL NO 16/678018
ART UNIT 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 16/0003 (20140204)
A61M 16/20 (20130101)
A61M 16/0063 (20140204)
A61M 16/101 (20140204) Original (OR) Class
A61M 16/105 (20130101)
A61M 16/107 (20140204)
A61M 16/0666 (20130101)
A61M 16/0672 (20140204)
A61M 16/0875 (20130101)
A61M 16/1005 (20140204)
A61M 2016/1025 (20130101)
A61M 2202/0208 (20130101)
A61M 2205/02 (20130101)
A61M 2205/42 (20130101)
A61M 2205/75 (20130101)
A61M 2205/3327 (20130101)
A61M 2205/3334 (20130101)
A61M 2205/8206 (20130101)

Separation
B01D 53/02 (20130101)
B01D 53/26 (20130101)
B01D 53/0415 (20130101)
B01D 53/0473 (20130101)
B01D 2253/108 (20130101)
B01D 2253/304 (20130101)
B01D 2256/12 (20130101)
B01D 2257/102 (20130101)
B01D 2259/4533 (20130101)
B01D 2259/4541 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 137/85938 (20150401)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11370794 Candia, III et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Dynavax Technologies Corporation (Berkeley, California)
ASSIGNEE(S) DYNAVAX TECHNOLOGIES CORPORATION (Berkeley, California)
INVENTOR(S) Albert Frederick Candia, III (San Mateo, California);  Richard Thomas Beresis (San Francisco, California);  Robert L. Coffman (Portola Valley, California)
ABSTRACT The invention relates to compounds of formula (I):
or a salt or solvate thereof, wherein the variables are as described herein. Compounds of formula (I), and pharmaceutical compositions thereof, are antagonists of toll-like receptors such as TLR7, TLR8, and/or TLR9. In certain embodiments, compounds of the invention are useful for inhibiting immune response and treating diseases associated with undesirable immune response.
FILED Thursday, November 09, 2017
APPL NO 16/348816
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 45/06 (20130101)

Heterocyclic Compounds
C07D 231/56 (20130101)
C07D 235/18 (20130101)
C07D 487/04 (20130101) Original (OR) Class
C07D 519/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11374654 Morton et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Morton Photonics (West Friendship, Maryland)
ASSIGNEE(S) Morton Photonics Inc (West Friendship, Maryland)
INVENTOR(S) Paul A. Morton (West Friendship, Maryland);  Jacob Khurgin (Pikesville, Maryland)
ABSTRACT High-performance ultra-wideband Phased Array Antennas (PAA) are disclosed, having unique capabilities, enabled through photonic integrated circuits and novel optical architectures. Unique capabilities for PAA systems are enabled by photonic integration and ultra-low-loss waveguides. Novel aspects include optical multiplexing combining wavelength division multiplexing and/or a novel extension to array photodetectors, providing the capability to combine many RF photonic signals with very low loss. Architectures include tunable optical up-conversion and down-conversion systems, moving a chosen frequency band between baseband and a high RF frequency band with high dynamic range. Simultaneous multi-channel RF beamforming is achieved through power combining/splitting of optical signals.
FILED Wednesday, April 07, 2021
APPL NO 17/224580
ART UNIT 2636 — Optical Communications
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 27/00 (20130101)

Antennas, i.e Radio Aerials
H01Q 3/2676 (20130101)

Transmission
H04B 10/40 (20130101)
H04B 10/50 (20130101)
H04B 10/60 (20130101)
H04B 10/66 (20130101)
H04B 10/67 (20130101)
H04B 10/69 (20130101)
H04B 10/516 (20130101)
H04B 10/671 (20130101)
H04B 10/697 (20130101)
H04B 10/6911 (20130101)
H04B 10/6971 (20130101)
H04B 10/6972 (20130101)
H04B 10/6973 (20130101)
H04B 10/25759 (20130101) Original (OR) Class
H04B 2210/006 (20130101)

Selecting
H04Q 5/00 (20130101)
H04Q 11/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 11369814 Thompson et al.
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
INVENTOR(S) William G. Thompson (Elizabeth City, North Carolina);  Mary Shalane Regan (Groton, Connecticut)
ABSTRACT A cover device for a regulator, which has a purge button and a mouthpiece connected to the regulator, includes a body having a mouthpiece housing to receive the mouthpiece through an access opening which presents a friction fit to squeeze the mouthpiece passing therethrough in a squeezed state to enter and exit a hollow interior of the mouthpiece housing. The hollow interior is configured to store the mouthpiece in a relaxed state. A button cover is connected to the mouthpiece housing to cover the purge button on a top surface of the regulator when the mouthpiece is inserted into the hollow interior of the mouthpiece housing. The button cover is narrower in width than the mouthpiece housing.
FILED Thursday, December 02, 2021
APPL NO 17/541100
ART UNIT 3785 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Devices, Apparatus or Methods for Life-saving
A62B 9/06 (20130101)
A62B 25/00 (20130101) Original (OR) Class

Launching, Hauling-out, or Dry-docking of Vessels; Life-saving in Water; Equipment for Dwelling or Working Under Water; Means for Salvaging or Searching for Underwater Objects
B63C 11/186 (20130101)
B63C 11/2227 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11373068 Hastings
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S) The Government of the United States of America, as represented bv the Secretary of Homeland Security (Washington, District of Columbia)
INVENTOR(S) William Hastings (Alexandria, Virginia)
ABSTRACT An improvement to automatic classifying of threat level of objects in CT scan images of container content, methods include automatic identification of non-classifiable threat level object images, and displaying on a display of an operator a de-cluttered image, to improve operator efficiency. The de-cluttered image includes, as subject images, the non-classifiable threat level object images. Improvement to resolution of non-classifiable threat objects includes computer-directed prompts for the operator to enter information regarding the subject image and, based on same, identifying the object type. Improvement to automatic classifying of threat levels includes incremental updating the classifying, using the determined object type and the threat level of the object type.
FILED Tuesday, October 12, 2021
APPL NO 17/499537
ART UNIT 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Electric Digital Data Processing
G06F 3/0481 (20130101)
G06F 3/0484 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/628 (20130101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 7/70 (20170101)
G06T 2200/24 (20130101)
G06T 2207/10081 (20130101)
G06T 2207/20092 (20130101)

Image or Video Recognition or Understanding
G06V 10/764 (20220101)
G06V 10/768 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11373387 Hastings et al.
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
INVENTOR(S) William Hastings (Alexandria, Virginia);  James Gilkeson (Alexandria, Virginia);  Douglas MacIvor (Arlington, Virginia)
ABSTRACT Various embodiments are directed toward systems and methods relating to security screening. For example, a screening system includes chamber scanners oriented to scan different heights corresponding to different respective portions of a user, to identify whether the user is carrying an item that is to be divested. The screening system also includes a divestment scanner configured to obtain a detailed item characterization of the item divested from the user.
FILED Thursday, January 28, 2021
APPL NO 17/161220
ART UNIT 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/10 (20130101)

Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags
G01V 3/08 (20130101)
G01V 3/165 (20130101)
G01V 5/005 (20130101)
G01V 5/0008 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/6288 (20130101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/20 (20130101)
G06Q 50/265 (20130101)

Image or Video Recognition or Understanding
G06V 10/40 (20220101)
G06V 10/147 (20220101) Original (OR) Class
G06V 20/10 (20220101)
G06V 2201/05 (20220101)

Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere
G07C 9/10 (20200101)
G07C 9/15 (20200101)
G07C 9/28 (20200101)
G07C 9/32 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 11370745 Biresaw et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Girma Biresaw (Peoria, Illinois);  Steven C. Cermak (Galesburg, Illinois);  Helen N. Lew (Wynnewood, Pennsylvania)
ABSTRACT A branched estolide compound of the formula:
wherein x and y are equal to 1 or greater;
wherein x+y=14;
wherein n is 0, 1, or greater than 1;
wherein R is H or wherein R=C1 to C18 straight alcohols or C4 to C12 branched alcohols;
wherein R1 is a residual fragment of octanoic, decanoic, lauric, coconut, myristic, palmitic, stearic, oleic, iso-stearic or iso-oleic acids.
FILED Monday, January 25, 2021
APPL NO 17/157046
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 69/67 (20130101)
C07C 69/675 (20130101) Original (OR) Class

Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition
C10M 105/34 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11371073 Quiñones et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Beatriz Quiñones (San Pablo, California);  Bertram G. Lee (San Francisco, California);  Jaszemyn C. Yambao (Fairfield, California)
ABSTRACT Provided are compositions, kits, and methods for the accurate detection of Listeria. In certain aspects and embodiments, the compositions, kits, and methods may provide improvements in relation to specificity, sensitivity, and speed of detection.
FILED Wednesday, March 11, 2020
APPL NO 16/815323
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/04 (20130101) Original (OR) Class
C12Q 1/686 (20130101)
C12Q 1/6853 (20130101)
C12Q 2561/113 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 11369381 Zayed et al.
FUNDED BY
Department of Veterans Affairs (DVA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) Washington University (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Mohamed Zayed (St. Louis, Missouri);  Dillon Williams (St. Louis, Missouri);  Guy Genin (St. Louis, Missouri);  Eric Leuthardt (St. Louis, Missouri)
ABSTRACT An arteriovenous graft and methods of reducing the risk of graft thrombosis and extending patency of the arteriovenous graft are provided herein. The arteriovenous graft is operable for attaching to a vein at a venous anastomosis. In some aspects, the arteriovenous graft includes a plurality of grooves at a venous anastomosis end of the arteriovenous graft and the venous anastomoses may be arranged such that the arteriovenous graft and the vein meet at an angle of 30° or less.
FILED Thursday, July 02, 2020
APPL NO 16/920221
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/11 (20130101) Original (OR) Class
A61B 2017/1107 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of the Interior (DOI) 

US 11370828 Westendorf et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Interior (DOI)
Interior Business Center (IBC)
Department of Health and Human Services (HHS)
APPLICANT(S) AbCellera Biologies Inc. (Vancouver, Canada);  The United States of America, as represented by the Secretary, Department of Health and Human Svcs. (Bethesda, Maryland)
ASSIGNEE(S) AbCellera Biologies Inc. (Vancouver, Canada);  The United States of America, as represented by the Secretary, Department of Health and Human Svcs. (Bethesda, Maryland)
INVENTOR(S) Kathryn Westendorf (Vancouver, Canada);  Stefanie Zentelis (Vancouver, Canada);  Krithika Muthuraman (Toronto, Canada);  Kevin Jepson (Vancouver, Canada);  Ester Falconer (Vancouver, Canada);  John Mascola (Bethesda, Maryland);  Barney Graham (Bethesda, Maryland);  Kizzmekia Corbett (Bethesda, Maryland);  Julie Ledgerwood (Bethesda, Maryland);  Lingshu Wang (Bethesda, Maryland);  Olubukola Abiona (Bethesda, Maryland);  Wei Shi (Bethesda, Maryland);  Wing-pui Kong (Bethesda, Maryland);  Yi Zhang (Bethesda, Maryland);  Bryan Edward Jones (San Diego, California);  Denisa Foster (San Diego, California);  Julian Davies (La Jolla, California);  Qing Chai (San Diego, California);  Christopher Carl Frye (Bargersville, Indiana);  Ganapathy Gopalrathnam (Fishers, Indiana);  Jörg Hendle (San Diego, California);  John Michael Sauder (Carlsbad, California);  Jeffrey Streetman Boyles (Indianapolis, Indiana);  Anna Pustilnik (San Diego, California)
ABSTRACT Antibodies that bind SARS-CoV spike protein, SARS-CoV-2 spike protein, and methods of using same for treating or preventing conditions associated with SARS or COVID-19 and for detecting SARS-CoV or SARS-CoV-2.
FILED Tuesday, June 22, 2021
APPL NO 17/354434
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/215 (20130101)
A61K 47/6801 (20170801)
A61K 2039/505 (20130101)

Peptides
C07K 16/10 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5091 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 11373388 Simpson
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Ryan J. Simpson (Vienna, Virginia)
ABSTRACT Embodiments of a system and method for sorting and delivering articles in a processing facility based on image data are described. Image processing results such as rotation notation information may be included in or with an image to facilitate downstream processing such as when the routing information cannot be extracted from the image using an unattended system and the image is passed to an attended image processing system. The rotation notation information may be used to dynamically adjust the image before presenting the image via the attended image processing system.
FILED Thursday, July 19, 2018
APPL NO 16/040344
ART UNIT 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking
B07C 3/20 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 7/1404 (20130101)

Image or Video Recognition or Understanding
G06V 10/25 (20220101) Original (OR) Class
G06V 10/242 (20220101)
G06V 30/40 (20220101)
G06V 30/413 (20220101)
G06V 30/424 (20220101)
G06V 30/1478 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, June 28, 2022.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20220628.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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