FedInvent™ Patents
Patent Details for Tuesday, July 19, 2022
This page was updated on Wednesday, July 20, 2022 at 06:31 AM GMT
Department of Health and Human Services (HHS)
US 11389095 | Rehan et al. |
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FUNDED BY |
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APPLICANT(S) | Los Angeles BioMedical Research Institute at Harbor UCLA Medical Center (Torrance, California); Intelligent Optical Systems (Torrance, California) |
ASSIGNEE(S) | Los Angeles BioMedical Research Institute at Harbor UCLA Medical Center (Torrance, California); Intelligent Optical Systems (Torrance, California) |
INVENTOR(S) | Virender Rehan (Torrance, California); Jesus Delgado (Torrance, California) |
ABSTRACT | Embodiments described herein relate to a catheter configured to detect at least one blood gas parameter present in blood in an artery of a patient, including, but not limited to, a catheter wall forming at least one lumen configured for umbilical arterial catheterization, at least one optical fiber incorporated in the catheter wall, wherein the at least one optical fiber is configured to detected the at least one blood gas parameter. |
FILED | Thursday, July 27, 2017 |
APPL NO | 16/321798 |
ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/1459 (20130101) A61B 5/4839 (20130101) A61B 5/6852 (20130101) A61B 5/14539 (20130101) A61B 5/14552 (20130101) A61B 5/14557 (20130101) Original (OR) Class A61B 5/150038 (20130101) A61B 2503/045 (20130101) A61B 2505/03 (20130101) A61B 2562/0233 (20130101) A61B 2562/0271 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389106 | Porges et al. |
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APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida); Johns Hopkins University, The (Baltimore, Maryland) |
ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida); The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Eric C. Porges (Gainesville, Florida); Damon Lamb (Gainesville, Florida); Martha Campbell Thompson (Micanopy, Florida); Richard Edden (Baltimore, Maryland) |
ABSTRACT | Aspects of the disclosure relate to systems and methods for obtaining and interpreting magnetic resonance spectroscopy (MRS) data obtained from the pancreas of a subject. In some embodiments, systems and methods of the disclosure relate to analyzing MRS spectra of metabolites, for example y-Aminobutyric acid (GABA), to assess pancreatic islet density and function in a subject. In some embodiments, systems and methods described by the disclosure are useful for the diagnosis and/or treatment of diseases associated with impaired pancreatic function, for example diabetes. |
FILED | Wednesday, October 17, 2018 |
APPL NO | 16/756489 |
ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/425 (20130101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 31/155 (20130101) A61K 38/28 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/485 (20130101) G01R 33/3415 (20130101) G01R 33/4616 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389127 | Sahbaee Bagherzadeh et al. |
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APPLICANT(S) | Siemens Healthcare GmbH (Erlangen, Germany); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
ASSIGNEE(S) | Siemens Healthcare GmbH (Erlangen, Germany); The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
INVENTOR(S) | Pooyan Sahbaee Bagherzadeh (Mount Pleasant, South Carolina); Babak Saboury Sichani (Laurel, Maryland); Faraz Farhadi (Fairfax, Virginia) |
ABSTRACT | A virtual 511 KeV attenuation map is generated from CT data. Spectral or multiple energy CT is used to more accurately extrapolate the 511 KeV attenuation map. Since spectral or multiple energy CT may allow for material decomposition and/or due to additional information in the form of measurements at different energies, the modeling used to generate the 511 KeV attenuation map may better account for all materials including high density material. The extrapolated 511 KeV attenuation map may more likely represent actual attenuation at 511 KeV without requiring extra scanning using a 511 KeV source external to the patient. The virtual 511 KeV attenuation map (e.g., CT data at 511 KeV) may provide more accurate PET image reconstruction. |
FILED | Monday, September 30, 2019 |
APPL NO | 16/587789 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/037 (20130101) A61B 6/481 (20130101) A61B 6/4417 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 2005/1098 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/046 (20130101) G01N 2223/3303 (20130101) G01N 2223/6126 (20130101) Image Data Processing or Generation, in General G06T 11/005 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389399 | Bellinger et al. |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Andrew Bellinger (Wellesley, Massachusetts); Shiyi Zhang (Shanghai, China PRC); Carlo Giovanni Traverso (Newton, Massachusetts); Robert S. Langer (Newton, Massachusetts); Stacy Mo (Darien, Illinois); Tyler Grant (Arlington, Massachusetts); Mousa Jafari (Waltham, Massachusetts); Dean Liang Glettig (Cambridge, Massachusetts); Angela DiCiccio (San Francisco, California); Lowell L. Wood, Jr. (Bellevue, Washington); Philip A. Eckhoff (Kirkland, Washington) |
ABSTRACT | Certain embodiments comprise administering a residence structure to a subject (e.g., a patient) such that the residence structure is retained at a location internal to the subject for a particular amount of time (e.g., at least about 24 hours) before being released. In certain embodiments, the structure has a modular design, combining a material configured for controlled release of therapeutic, diagnostic, and/or enhancement agents with a structural material necessary for gastric residence but configured for controlled and/or tunable degradation/dissolution to determine the time at which retention shape integrity is lost and the structure passes out of the gastric cavity. For example, in certain embodiments, the residence structure comprises a first elastic component, a second component configured to release an active substance, and, optionally, a linker. In some such embodiments, the linker may be configured to degrade. |
FILED | Friday, December 18, 2020 |
APPL NO | 17/126835 |
ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/48 (20130101) A61K 9/0053 (20130101) A61K 9/0065 (20130101) Original (OR) Class A61K 31/65 (20130101) A61K 31/357 (20130101) A61K 31/7048 (20130101) A61K 47/10 (20130101) A61K 47/32 (20130101) A61K 47/34 (20130101) A61K 47/40 (20130101) A61K 47/42 (20130101) A61K 47/58 (20170801) A61K 47/6901 (20170801) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 31/002 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/73 (20130101) C08G 18/4277 (20130101) C08G 63/08 (20130101) C08G 83/006 (20130101) C08G 2230/00 (20130101) Compositions of Macromolecular Compounds C08L 33/02 (20130101) C08L 33/08 (20130101) C08L 33/14 (20130101) C08L 2203/02 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389414 | Linton et al. |
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APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
INVENTOR(S) | Macrae F. Linton (Nashville, Tennessee); John A. Oates (Nashville, Tennessee); Sean S. Davies (Nashville, Tennessee); L. Jackson Roberts, II (Gallatin, Tennessee); Venkataraman Amarnath (Brentwood, Tennessee); Patricia G. Yancey (Nashville, Tennessee); Huan Tao (Nashville, Tennessee) |
ABSTRACT | A method of treating atherosclerosis, comprising administering to a patient in need there of an effective gamma-ketoaldehyde scavenging amount of a gamma-ketoaldehyde scavenging compound. |
FILED | Friday, April 27, 2018 |
APPL NO | 16/607700 |
ART UNIT | 1622 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/135 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389415 | Wainer et al. |
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APPLICANT(S) | The United States of America as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
ASSIGNEE(S) | The United States of America, as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); Secretary, Department of Health and Human Services (Bethesda, Maryland) |
INVENTOR(S) | Irving W. Wainer (Washington, District of Columbia); Michel Bernier (Pikesville, Maryland); Rajib K. Paul (Baltimore, Maryland) |
ABSTRACT | This disclosure concerns the discovery of the use of fenoterol analogues for regulating cannabinoid (CB) receptor activity-related disorders and disease, such as dysregulated CB receptors, including treating a disorder or disease, such as a glioblastoma, hepatocellular carcinoma, liver cancer, colon cancer, and/or lung cancer, which is associated with altered cannabinoid receptor activity. In one example, the method includes administering to a subject having or at risk of developing a disorder or disease regulated by CB receptor activity an effective amount of a fenoterol analogue to reduce one or more symptoms associated with the disorder or disease regulated by CB receptor activity. |
FILED | Thursday, August 13, 2020 |
APPL NO | 16/992742 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/05 (20130101) A61K 31/137 (20130101) Original (OR) Class A61K 45/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389422 | Lin et al. |
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APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
INVENTOR(S) | Wenbin Lin (Chicago, Illinois); Christina Chan (Chicago, Illinois); Wenbo Han (Chicago, Illinois) |
ABSTRACT | Nanoparticles comprising micheliolide (MCL) or derivatives thereof, and optionally additional therapeutic agents, such as chemotherapeutic agents, are described. Also described are methods of treating diseases, such as cancer, comprising the use of combinations of MCL or a derivative thereof with X-ray irradiation and/or other therapeutic agents, such as immune checkpoint inhibitors. The use of the combinations can provide synergistic anticancer therapeutic efficacy, for example, as the MCL or derivative thereof can both sensitize cancer cells to therapy and target resistant cancer stem cells (CSCs) for selective cell death. |
FILED | Monday, April 27, 2020 |
APPL NO | 16/859594 |
ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/343 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 47/6803 (20170801) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 37/00 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389427 | Zhang et al. |
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APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio); SAINT LOUIS UNIVERSITY (St. Louis, Missouri) |
ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
INVENTOR(S) | Lilei Zhang (Cleveland Heights, Ohio); Mukesh K. Jain (Solon, Ohio); Thomas Burris (Columbia, Illinois) |
ABSTRACT | A method of treating cardiac hypertrophy and/or heart failure in a subject includes administering to the subject a therapeutically effective amount of a REV-ERBα agonist. |
FILED | Friday, February 09, 2018 |
APPL NO | 16/485359 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 31/381 (20130101) A61K 31/4025 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389430 | Raffay et al. |
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APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
INVENTOR(S) | Thomas M. Raffay (Cleveland, Ohio); Benjamin M. Gaston (Cleveland, Ohio) |
ABSTRACT | A method of treating a hyperoxia induced disease or disorder associated with GSNO deficiency in a subject in need thereof includes administering to the subject a therapeutically effective amount of GSNO or a GSNO promoting agent. |
FILED | Tuesday, January 21, 2020 |
APPL NO | 16/748588 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0078 (20130101) A61K 31/4178 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389439 | John et al. |
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APPLICANT(S) | The Jackson Laboratory (Bar Harbor, Maine) |
ASSIGNEE(S) | The Jackson Laboratory (Bar Harbor, Maine) |
INVENTOR(S) | Simon W. M. John (Bar Harbor, Maine); Peter Alexander Williams (Tremont, Maine) |
ABSTRACT | The invention relates to the use of a pharmaceutical composition containing nicotinamide (NAM) and/or pyruvate as a neuroprotective medicament or gene therapy in the treatment of neurodegenerative disorders, in particular axon degeneration of neuronal tissue in ocular-related neurodegeneration diseases including glaucoma. |
FILED | Monday, April 23, 2018 |
APPL NO | 15/959379 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/19 (20130101) A61K 31/19 (20130101) A61K 31/455 (20130101) Original (OR) Class A61K 31/455 (20130101) A61K 31/706 (20130101) A61K 31/706 (20130101) A61K 31/4745 (20130101) A61K 31/4745 (20130101) A61K 38/00 (20130101) A61K 38/45 (20130101) A61K 45/06 (20130101) A61K 48/00 (20130101) A61K 48/005 (20130101) A61K 48/0075 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/06 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2750/14143 (20130101) Enzymes C12Y 207/07001 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389455 | Andrake et al. |
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APPLICANT(S) | Institute for Cancer Research (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | Institute for Cancer Research (Philadelphia, Pennsylvania) |
INVENTOR(S) | Mark D. Andrake (Philadelphia, Pennsylvania); Anna Marie Skalka (Philadelphia, Pennsylvania); George W. Merkel (Philadelphia, Pennsylvania) |
ABSTRACT | The disclosure generally relates to compounds, compositions, and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV-1 integrase, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection. |
FILED | Wednesday, December 30, 2020 |
APPL NO | 17/138581 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/53 (20130101) Original (OR) Class A61K 31/454 (20130101) A61K 31/4245 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389459 | Sessler et al. |
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APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
INVENTOR(S) | Jonathan L. Sessler (Austin, Texas); Jonathan Arambula (Austin, Texas); Zahid H. Siddik (Houston, Texas); Gregory Thiabaud (Austin, Texas) |
ABSTRACT | The present disclosure relates platinum(IV) and texaphyrin linked conjugates and compositions comprising a texaphyrin and a platinum(IV) agent. The present disclosure also provides pharmaceutical compositions of the conjugates and compositions. Also, provided herein are methods of using the instant compounds in the treatment of cancer such as a platinum resistant cancer. |
FILED | Friday, September 06, 2019 |
APPL NO | 16/563714 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/555 (20130101) Original (OR) Class A61K 47/60 (20170801) A61K 47/546 (20170801) A61K 47/547 (20170801) A61K 49/10 (20130101) A61K 49/085 (20130101) A61K 49/106 (20130101) Heterocyclic Compounds C07D 487/22 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/0093 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389460 | Dellinger |
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APPLICANT(S) | City of Hope (Duarte, California) |
ASSIGNEE(S) | CITY OF HOPE (Duarte, California) |
INVENTOR(S) | Thanh Dellinger (Azusa, California) |
ABSTRACT | Provided herein are, inter alia, methods and compositions for treating cancer in a subject in need thereof comprising a therapeutically effective amount of a stilbenoid compound and a progestin. |
FILED | Friday, September 14, 2018 |
APPL NO | 16/131985 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/10 (20130101) A61K 9/48 (20130101) A61K 9/0053 (20130101) A61K 9/0095 (20130101) A61K 9/2004 (20130101) A61K 31/09 (20130101) A61K 31/57 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389465 | Sherwood et al. |
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APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
INVENTOR(S) | Edward Sherwood (Nashville, Tennessee); Antonio Hernandez (Franklin, Tennessee); Julia Bohannon (Nashville, Tennessee) |
ABSTRACT | The present disclosure relates to phosphorylated hexaacyl disaccharide (PHAD) compounds, compositions, and methods for treating or preventing infections. |
FILED | Tuesday, May 01, 2018 |
APPL NO | 16/610125 |
ART UNIT | 1623 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7016 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389480 | Oppenheim et al. |
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APPLICANT(S) | The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
INVENTOR(S) | Joost J. Oppenheim (Bethesda, Maryland); Dimiter S. Dimitrov (Pittsburgh, Pennsylvania); De Yang (Frederick, Maryland); Xin Chen (Frederick, Maryland); Zhongyu Zhu (Frederick, Maryland) |
ABSTRACT | A human monoclonal antibody that specifically binds tumor necrosis factor receptor 2 (TNFR2), and a defucosylated form of the antibody, are described. The TNFR2-specific antibody was isolated from a human scFv phage display antibody library. The disclosed antibodies promote antibody-dependent cell-mediated cytotoxicity (ADCC) of human TNFR2+ CD4+ T regulatory cells in a dose- and time-dependent manner. Methods of using the TNFR2 antibodies, such as for tumor immunotherapy, are described. |
FILED | Tuesday, May 08, 2018 |
APPL NO | 16/614652 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 47/6415 (20170801) A61K 47/6929 (20170801) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2809 (20130101) C07K 16/2878 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389483 | Ji et al. |
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APPLICANT(S) | Duke University (Durham, North Carolina) |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Ru-Rong Ji (Durham, North Carolina); Gang Chen (Durham, North Carolina) |
ABSTRACT | Disclosed herein are bone marrow stromal cells. The bone marrow stromal cells may express and/or secrete TGF-βI. The bone marrow stromal cells may express CXCR4. Also disclosed herein is a method of treating pain in a subject in need thereof. The method of treating may include administration of the bone marrow stromal cells to the subject. The pain may be neuropathic pain. |
FILED | Friday, July 08, 2016 |
APPL NO | 15/743208 |
ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 35/28 (20130101) Original (OR) Class A61K 35/28 (20130101) A61K 38/1841 (20130101) A61K 38/1841 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389509 | Filiano et al. |
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APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
INVENTOR(S) | Anthony J. Filiano (Charlottesville, Virginia); Jonathan Kipnis (Charlottesville, Virginia) |
ABSTRACT | The present disclosure relates to methods of treating social dysfunction neurological disorders in an animal subject, comprising administering to the subject a therapeutically effective amount of a compound that increases STAT1 activity, and to a method of treating seizures in an animal subject, comprising administering to the subject a therapeutically effective amount of a compound that increases STAT1 activity. In some embodiments, the compound is IFN-γ. |
FILED | Wednesday, July 11, 2018 |
APPL NO | 16/033160 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0019 (20130101) A61K 31/5513 (20130101) A61K 38/17 (20130101) A61K 38/217 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/08 (20180101) A61P 25/28 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389517 | Shea et al. |
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APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
INVENTOR(S) | Lonnie D. Shea (Evanston, Illinois); Stephen D. Miller (Evanston, Illinois); Jonathan Woon Teck Yap (Evanston, Illinois); Daniel R. Getts (Northbrook, Illinois); Derrick McCarthy (Evanston, Illinois) |
ABSTRACT | The present invention provides compositions comprising peptide-coupled biodegradable poly(lactide-co-glycolide) (PLG) particles. In particular, PLG particles are surface-functionalized to allow for coupling of peptide molecules to the surface of the particles (e.g., for use in eliciting induction of immunological tolerance). |
FILED | Wednesday, June 30, 2021 |
APPL NO | 17/364351 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/19 (20130101) A61K 9/1647 (20130101) A61K 9/5153 (20130101) A61K 39/00 (20130101) A61K 39/0008 (20130101) Original (OR) Class A61K 47/58 (20170801) A61K 47/6911 (20170801) A61K 47/6935 (20170801) A61K 47/6937 (20170801) A61K 2039/577 (20130101) A61K 2039/622 (20130101) A61K 2039/55555 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389521 | Balint et al. |
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APPLICANT(S) | Etubics Corporation (Seatle, Washington) |
ASSIGNEE(S) | Etubics Corporation (Seattle, Washington) |
INVENTOR(S) | Joseph P. Balint (Seattle, Washington); Frank R. Jones (Seattle, Washington); Richard B. Gayle, III (Woodinville, Washington) |
ABSTRACT | Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided. |
FILED | Monday, April 27, 2020 |
APPL NO | 16/859490 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/191 (20130101) A61K 38/193 (20130101) A61K 38/204 (20130101) A61K 38/208 (20130101) A61K 38/217 (20130101) A61K 38/2013 (20130101) A61K 38/2026 (20130101) A61K 38/2033 (20130101) A61K 38/2046 (20130101) A61K 38/2066 (20130101) A61K 39/00 (20130101) A61K 39/0011 (20130101) A61K 39/12 (20130101) Original (OR) Class A61K 39/21 (20130101) A61K 39/235 (20130101) A61K 39/001106 (20180801) A61K 39/001182 (20180801) A61K 2039/54 (20130101) A61K 2039/57 (20130101) A61K 2039/545 (20130101) A61K 2039/575 (20130101) A61K 2039/5256 (20130101) A61K 2039/55555 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/005 (20130101) C07K 14/71 (20130101) C07K 14/70503 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2710/10034 (20130101) C12N 2710/10321 (20130101) C12N 2710/10334 (20130101) C12N 2710/10343 (20130101) C12N 2710/10371 (20130101) C12N 2710/20034 (20130101) C12N 2740/15034 (20130101) C12N 2740/16234 (20130101) C12N 2800/24 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389522 | Galarza et al. |
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FUNDED BY |
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APPLICANT(S) | TechnoVax, Inc. (Elmsford, New York) |
ASSIGNEE(S) | TECHNOVAX, INC. (Elmsford, New York) |
INVENTOR(S) | Jose M. Galarza (Elmsford, New York); Helene Boigard (Elmsford, New York); George Martin (Elmsford, New York) |
ABSTRACT | Flavivirus virus-like particles (VLPs) are provided that display on their surfaces antigenic flavivirus proteins. The VLPs include at least one flavivirus structural protein and at least one non-structural flavivirus protein. A DNA construct that includes sequences encoding flavivirus viral proteins used to assemble the flavivirus VLP is also provided. A method of producing flavivirus VLPs by introducing one or more the DNA constructs into a host cell is also provided. An immunogenic composition that includes the flavivirus VLP is also provided. |
FILED | Friday, September 04, 2020 |
APPL NO | 17/013156 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 39/145 (20130101) A61K 2039/5258 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 9/506 (20130101) C12N 2770/24023 (20130101) C12N 2770/24034 (20130101) C12N 2770/24134 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389523 | Kawaoka et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
INVENTOR(S) | Yoshihiro Kawaoka (Middleton, Wisconsin); Gabriele Neumann (Madison, Wisconsin); Huihui Kong (Madison, Wisconsin) |
ABSTRACT | Methods of preparing influenza viruses having altered immunodominant epitopes in HA, e.g., having one or more residues in one or more of antigenic sites A-E in HA altered, and viral vectors, e.g., influenza virus VLPs or non-influenza viruses or VLPs thereof expressing or having influenza HAs with altered immunogenicity as a result of altered immunodominant epitopes therein are provided. |
FILED | Tuesday, August 20, 2019 |
APPL NO | 16/545761 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/145 (20130101) Original (OR) Class A61K 2039/521 (20130101) A61K 2039/5258 (20130101) Peptides C07K 16/34 (20130101) C07K 16/1018 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389526 | Zeng et al. |
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FUNDED BY |
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APPLICANT(S) | Texas Tech University System (Lubbock, Texas) |
ASSIGNEE(S) | Texas Tech University System (Lubbock, Texas) |
INVENTOR(S) | Mingtao Zeng (El Paso, Texas); Ke Wen (Harrison, New York) |
ABSTRACT | The present invention includes a live, self-attenuated therapeutic vaccine, virus and methods of making and using the same, comprising: an isolated virus comprising a viral genome that expresses one or more viral antigens; and an artificial microRNA 30 (amiR-30) expression cassette inserted into a viral neuraminidase (NA) or a viral non-structural (NS) gene segment that expresses an amiR-30 that specifically inhibits the expression of a host gene essential for influenza virus replication in host cells. |
FILED | Thursday, April 18, 2019 |
APPL NO | 17/048714 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) A61K 39/145 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/5254 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/1131 (20130101) C12N 2310/141 (20130101) C12N 2760/16134 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389529 | Wussow et al. |
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FUNDED BY |
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APPLICANT(S) | CITY OF HOPE (Duarte, California) |
ASSIGNEE(S) | CITY OF HOPE (Duarte, California) |
INVENTOR(S) | Felix Wussow (Monrovia, California); Don J. Diamond (Glendora, California) |
ABSTRACT | An expression system for expressing a herpesvirus glycoprotein complex including a vector inserted with two or more nucleic acid sequences that encode two or more subunits of a herpesvirus glycoprotein complex linked by one or more linking sequences such that the subunits are co-expressed simultaneously and self-processed to assemble into a glycoprotein complex. The expression system or the vector can be included in a vaccine composition. The vaccine composition can be used for preventing or treating herpesvirus infections. |
FILED | Friday, July 13, 2018 |
APPL NO | 16/630624 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/245 (20130101) Original (OR) Class Peptides C07K 14/05 (20130101) C07K 14/045 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389530 | Sampson et al. |
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FUNDED BY |
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APPLICANT(S) | Duke University (Durham, North Carolina) |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | John H Sampson (Durham, North Carolina); Duane A Mitchell (Durham, North Carolina) |
ABSTRACT | The present invention relates to compositions, methods, and kits for eliciting an immune response to at least one CMV antigen expressed by a cancer cell, in particular for treating and preventing cancer. CMV determination methods, compositions, and kits also are provided. |
FILED | Wednesday, March 18, 2020 |
APPL NO | 16/822354 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) A61K 39/12 (20130101) A61K 39/39 (20130101) A61K 39/245 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2039/53 (20130101) A61K 2039/5154 (20130101) A61K 2039/5156 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/16122 (20130101) C12N 2710/16134 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389547 | Kariko et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Katalin Kariko (Rydal, Pennsylvania); Drew Weissman (Wynnewood, Pennsylvania) |
ABSTRACT | This invention provides RNA, oligoribonucleotide, and polyribonucleotide molecules comprising pseudouridine or a modified nucleoside, gene therapy vectors comprising same, methods of synthesizing same, and methods for gene replacement, gene therapy, gene transcription silencing, and the delivery of therapeutic proteins to tissue in vivo, comprising the molecules. The present invention also provides methods of reducing the immunogenicity of RNA, oligoribonucleotide, and polyribonucleotide molecules. |
FILED | Tuesday, March 12, 2019 |
APPL NO | 16/299202 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/50 (20130101) A61K 38/177 (20130101) A61K 38/1816 (20130101) A61K 48/00 (20130101) A61K 48/005 (20130101) A61K 48/0041 (20130101) A61K 48/0066 (20130101) Original (OR) Class A61K 48/0075 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Peptides C07K 14/47 (20130101) C07K 14/505 (20130101) C07K 14/4712 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/67 (20130101) C12N 15/85 (20130101) C12N 15/117 (20130101) C12N 2310/17 (20130101) C12N 2310/33 (20130101) C12N 2310/3341 (20130101) C12N 2800/95 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) Enzymes C12Y 305/04004 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389552 | Oeffinger et al. |
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FUNDED BY |
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APPLICANT(S) | Thomas Jefferson University (Philadelphia, Pennsylvania); Drexel University (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | Thomas Jefferson University (Philadelphia, Pennsylvania); Drexel University (Philadelphia, Pennsylvania) |
INVENTOR(S) | Brian Edward Oeffinger (Philadelphia, Pennsylvania); Margaret A. Wheatley (Media, Pennsylvania); Rawan Shraim (Philadelphia, Pennsylvania); Purva Vaidya (Flushing, New York); John Robert Eisenbrey (Wayne, Pennsylvania) |
ABSTRACT | One aspect of the invention provides a method for freeze-drying surfactant-stabilized microbubbles. The method includes: preparing vials comprising a mixture comprising microbubbles; partially submerging the vials in a chilled water bath, wherein the water bath has a sub-freezing temperature; placing the vials on a cooled shelf of a lyophilizer; freeze-drying the vials in the lyophilizer; and capping the freeze-dried vials. Another aspect of the invention provides a method for annealing surfactant-stabilized microbubbles. The method includes: preparing vials comprising a mixture comprising microbubbles; passing the vials in and out of liquid nitrogen (LN2) until the mixture is frozen; holding the vials at −20° C.; placing the vials on a cooled shelf of a lyophilizer; freeze-drying the vials in the lyophilizer; and capping the freeze-dried vials. |
FILED | Friday, March 13, 2020 |
APPL NO | 16/817898 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/223 (20130101) Original (OR) Class A61K 49/227 (20130101) A61K 2800/84 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389569 | Badylak et al. |
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FUNDED BY |
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APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Stephen F. Badylak (West Lafayette, Indiana); Hong Jiang (Export, Pennsylvania); Hideyoshi Sato (Pittsburgh, Pennsylvania); William R. Wagner (Gibsonia, Pennsylvania); Yang Zhu (Pittsburgh, Pennsylvania) |
ABSTRACT | An injectable hydrogel composition that forms a porous gel rapidly after injection fro tissue engineering. The composition comprises a biodegradable, biocompatible, gelling polymer, that is optionally reverse-gelling; an Extra cellular matrix (ECM) material and a biocompatible porogen. Methods of making and using the composition are provided. A kit also is provided comprising the ingredients for making the hydrogel. |
FILED | Tuesday, April 03, 2018 |
APPL NO | 16/496480 |
ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/26 (20130101) A61L 27/48 (20130101) A61L 27/52 (20130101) A61L 27/56 (20130101) Original (OR) Class Compositions of Macromolecular Compounds C08L 33/24 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389668 | Jin et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Indiana University (Indianapolis, Indiana) |
ASSIGNEE(S) | The Trustees of Indiana University (Indianapolis, Indiana) |
INVENTOR(S) | Jian-Yue Jin (Indianapolis, Indiana); Feng-Ming Kong (Indianapolis, Indiana); Hong Zhang (Wilmington, Delaware); Huan Yao (Indianapolis, Indiana) |
ABSTRACT | Methods for calculating the radiation dose to the immune system of a patient undergoing radiotherapy are provided. In particular, the methods provide for calculating an effective dose to blood (EDIC) to circulating immune cells. The methods can be incorporated into radiotherapy (RT) treatment planning systems, which are also provided. The methods can be used to optimize patient treatment plans. Methods for treating a patient with RT with an optimized treatment plan are provided. |
FILED | Wednesday, May 02, 2018 |
APPL NO | 16/968849 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1031 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389799 | Burns et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
INVENTOR(S) | Mark A. Burns (Ann Arbor, Michigan); Alyse D. Krausz (Ann Arbor, Michigan); Sarah Elizabeth Mena (Ann Arbor, Michigan); Martin Patrick De Beer (Ann Arbor, Michigan); Kevin R. Ward (Superior Township, Michigan); Frederick Korley (Ann Arbor, Michigan) |
ABSTRACT | A microfluidic device system includes a channel having an entrance and an exit, a height at the entrance being greater than a height at the exit. The height of the channel may decrease continuously from the height at the entrance to the height at the exit. Cells or particles or beads traveling through the channel become trapped based on their size and/or deformability. A visual sensor captures images of the trapped cells or particles or beads, and image software analyzes the captured images to provide size and/or deformability and/or fluorescence information. A method of fabricating such a microfluidic device includes introducing a glass wafer to an etching solution at a specific rate such that a first end of the glass wafer is etched longer than other portions of the glass wafer. |
FILED | Friday, January 17, 2020 |
APPL NO | 16/746408 |
ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 3/502715 (20130101) B01L 3/502761 (20130101) Original (OR) Class B01L 2200/12 (20130101) B01L 2200/0668 (20130101) B01L 2300/0627 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/28 (20130101) G01N 15/1475 (20130101) G01N 21/6428 (20130101) G01N 33/6803 (20130101) G01N 33/54366 (20130101) G01N 2015/1493 (20130101) G01N 2021/6439 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390580 | Del Poeta et al. |
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FUNDED BY |
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APPLICANT(S) | Maurizio Del Poeta (Mount Sinai, New York); Visesato Mor (Nagaland, India) |
ASSIGNEE(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
INVENTOR(S) | Maurizio Del Poeta (Mount Sinai, New York); Visesato Mor (Nagaland, India) |
ABSTRACT | The present invention provides a compound having the structure: |
FILED | Monday, June 24, 2019 |
APPL NO | 16/450772 |
ART UNIT | 1622 — Organic Chemistry |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/28 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/16 (20130101) A61K 31/16 (20130101) A61K 31/166 (20130101) A61K 31/4196 (20130101) A61K 31/4196 (20130101) A61K 31/7048 (20130101) A61K 31/7048 (20130101) A61K 31/7072 (20130101) A61K 31/7072 (20130101) A61K 38/12 (20130101) A61K 38/12 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Acyclic or Carbocyclic Compounds C07C 251/86 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390585 | Stoltz et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Brian M. Stoltz (San Marino, California); Scott C. Virgil (Pasadena, California); David E. White (Wayne, Pennsylvania); Taiga Yurino (Kyoto, Japan); Yiyang Liu (Pasadena, California); Douglas C. Behenna (Laguna Niguel, California); Douglas Duquette (Los Angeles, California); Christian Eidamshaus (Pasadena, California) |
ABSTRACT | The invention provides heterocyclic compounds with quaternary centers and methods of preparing compounds. Methods include the method for the preparation of a compound of Formula (II): comprising treating a compound of Formula (I): with a transition metal catalyst and under alkylation conditions as valence and stability permit. |
FILED | Monday, February 01, 2021 |
APPL NO | 17/164204 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 207/06 (20130101) C07D 207/08 (20130101) C07D 207/10 (20130101) C07D 207/16 (20130101) C07D 207/26 (20130101) C07D 207/27 (20130101) C07D 207/46 (20130101) C07D 207/263 (20130101) C07D 207/267 (20130101) C07D 207/273 (20130101) C07D 207/277 (20130101) C07D 211/16 (20130101) C07D 211/18 (20130101) C07D 211/22 (20130101) C07D 211/34 (20130101) C07D 211/38 (20130101) C07D 211/60 (20130101) C07D 211/76 (20130101) C07D 211/78 (20130101) Original (OR) Class C07D 211/88 (20130101) C07D 211/90 (20130101) C07D 211/94 (20130101) C07D 211/96 (20130101) C07D 223/04 (20130101) C07D 223/10 (20130101) C07D 241/04 (20130101) C07D 241/08 (20130101) C07D 241/52 (20130101) C07D 265/30 (20130101) C07D 265/32 (20130101) C07D 309/04 (20130101) C07D 309/30 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390613 | Hadden |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF CONNECTICUT (Farmington, Connecticut) |
ASSIGNEE(S) | UNIVERSITY OF CONNECTICUT (Farmington, Connecticut) |
INVENTOR(S) | Matthew Kyle Hadden (Ellington, Connecticut) |
ABSTRACT | Disclosed herein are analogues of itraconazole that are both angiogenesis and hedgehog signaling pathway inhibitors, formulations thereof, including liposome formulations thereof. The compounds are expected to be useful in the treatment of cell proliferation disorders such as cancer, particularly cancers that are dependent upon the hedgehog signaling pathway such as basal cell carcinoma and medulloblastoma. |
FILED | Monday, August 20, 2018 |
APPL NO | 16/639242 |
ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/38 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 405/12 (20130101) C07D 405/14 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390626 | Garland et al. |
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FUNDED BY |
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APPLICANT(S) | Tosk, Inc. (Mountain View, California) |
ASSIGNEE(S) | Tosk, Inc. (Mountain View, California) |
INVENTOR(S) | William A. Garland (Mountain View, California); Solomon B. Ungashe (Mountain View, California); Stephen D. Yanofsky (Mountain View, California); Philip Liaw (Mountain View, California); Annie L. Lennek (Mountain View, California) |
ABSTRACT | Pyrazolopyrimidine RAS modulating compounds and methods of using the same are provided. The pyrazolopyrimidine compounds find use in modulating the activity of a target RAS in a sample. The target RAS can be a mutant RAS that is implicated in a disease of interest. In some cases, the subject compounds can inhibit the growth of cancer cells whose progression is driven by kRAS or a mutated kRAS. Methods of treating a subject for a RAS driven disease including administering a therapeutically effective amount of the subject compound are provided. Also provided are pharmaceutical compositions and kits which include the subject compounds. |
FILED | Tuesday, January 28, 2020 |
APPL NO | 16/774381 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390629 | Vlaar et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF PUERTO RICO (San Juan, Puerto Rico) |
ASSIGNEE(S) | UNIVERSITY OF PUERTO RICO (San Juan, Puerto Rico) |
INVENTOR(S) | Cornelis P. Vlaar (San Juan, Puerto Rico); Suranganie Dharmawardhane Flanagan (San Juan, Puerto Rico); Eliud Hernandez-O'Farrill (San Juan, Puerto Rico); Linette Castillo-Pichardo (San Juan, Puerto Rico) |
ABSTRACT | Compounds are disclosed that inhibit RhoGTPases that are useful for inhibiting hyperproliferative and neoplastic diseases. Specifically, the compounds inhibit the GTPases Rac and Cdc42 that are overactive or overexpressed in signaling pathways in cancer and metastasis. Methods for treatment of cancer and hyperproliferative diseases are disclosed. |
FILED | Thursday, April 01, 2021 |
APPL NO | 17/220319 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 401/14 (20130101) C07D 403/04 (20130101) C07D 403/14 (20130101) C07D 409/14 (20130101) C07D 491/048 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390630 | Ghosh et al. |
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FUNDED BY |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Arun K. Ghosh (West Lafayette, Indiana); Hiroaki Mitsuya (Kumamoto, Japan); Prasanth Reddy Nyalapatla (Henrico, Virginia) |
ABSTRACT | Various embodiments relate to a compound of the formula (I) and (II), wherein X, X1, X2, X3, and R1-R4 are defined herein, as well as pharmaceutical compositions comprising compounds of the formula (I) and/or (II) and methods of treating an HIV infection comprising administering a therapeutically effective amount of one or more compounds of formula (I) and/or (II), or a pharmaceutical composition comprising compounds of the formula (I) and/or (II), to a patient in need thereof. |
FILED | Tuesday, May 04, 2021 |
APPL NO | 17/307905 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 311/78 (20130101) C07D 493/06 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390640 | Blagg et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF KANSAS (Lawrence, Kansas) |
ASSIGNEE(S) | UNIVERSITY OF KANSAS (Lawrence, Kansas) |
INVENTOR(S) | Brian S. J. Blagg (Lawrence, Kansas); Bhaskar Reddy Kusuma (Lake Ronkonkoma, New York); Teather Sundstrom (Eckelson, North Dakota) |
ABSTRACT | Hsp90 C-terminal inhibitors and pharmaceutical compositions containing such compounds are provided. The compounds of the disclosure are useful for the treatment and/or prevention of neurodegenerative disorders such as diabetic peripheral neuropathy. |
FILED | Friday, December 04, 2020 |
APPL NO | 17/112060 |
ART UNIT | 1623 — Organic Chemistry |
CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 211/17 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/203 (20130101) C07H 15/207 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390644 | Dai et al. |
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FUNDED BY |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Mingji Dai (West Lafayette, Indiana); Ji-Xin Cheng (Newton, Massachusetts) |
ABSTRACT | A method of forming a probe, wherein the method includes converting cholenic acid into a compound with a terminal alkyne group, wherein the converting the cholenic acid comprises using a sequence, wherein the sequence comprises synthesizing a THP-protection group, LiAlH4 reduction, Dess-Martin oxidation, and Seyferth-Gilbert-Bestmann homologation. The method additionally includes forming A-Chol by removing the THP-protection. Further, the method includes forming PhA-Chol from the compound with the terminal alkyne group via a palladiumcatalyzed Sonogashira reaction. Additionally, the method includes forming PhDY Chol from the compound with the terminal alkyne group via a coppercatalyzed Cadiot-Chodkiewicz reaction. |
FILED | Tuesday, November 20, 2018 |
APPL NO | 16/197250 |
ART UNIT | 1622 — Organic Chemistry |
CURRENT CPC | Steroids C07J 9/00 (20130101) Original (OR) Class C07J 9/005 (20130101) C07J 17/00 (20130101) C07J 41/0094 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/52 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390646 | Eisenberg et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | David S. Eisenberg (Los Angeles, California); Smriti Sangwan (Los Angeles, California); Lin Jiang (Santa Monica, California) |
ABSTRACT | This invention relates to inhibitory peptides which bind to α-synuclein molecules and inhibit α-synuclein amyloidogenic aggregation, α-synuclein cytotoxicity, and spread of α-synuclein. Methods of making and using the inhibitory peptides (e.g. to treat subjects having conditions or diseases that are mediated by α-synuclein, such as Parkinson's disease, dementia with Lewy bodies, or MSA) are described. |
FILED | Tuesday, May 26, 2020 |
APPL NO | 16/883515 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/16 (20180101) Peptides C07K 7/02 (20130101) Original (OR) Class C07K 7/08 (20130101) C07K 14/47 (20130101) C07K 14/4711 (20130101) C07K 2319/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) G01N 2800/2835 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390649 | Kawaoka et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
INVENTOR(S) | Yoshihiro Kawaoka (Middleton, Wisconsin); Gabriele Neumann (Madison, Wisconsin); Jihui Ping (Nanjing, China PRC) |
ABSTRACT | An isolated recombinant influenza virus is provided having PA, PB1, PB2, NP, NS, M, NA and HA viral segments, wherein the PB1 viral segment encodes a PB1 with a residue other than isoleucine at position 711 or the M viral segment encodes a M1 with a residue other than methionine at position 128, wherein the recombinant influenza virus has enhanced replication relative to a corresponding influenza virus having a PB1 viral segment that encodes a PB1 with an isoleucine at position 711 or having a M viral segment that encodes a M1 with methionine at position 128, as well as methods of making and using the virus. |
FILED | Friday, May 01, 2020 |
APPL NO | 16/865194 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/007 (20130101) A61K 9/0019 (20130101) A61K 39/145 (20130101) A61K 2039/54 (20130101) A61K 2039/544 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/16 (20180101) Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2760/16121 (20130101) C12N 2760/16122 (20130101) C12N 2760/16134 (20130101) C12N 2760/16152 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390650 | Yao |
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FUNDED BY |
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APPLICANT(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
ASSIGNEE(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
INVENTOR(S) | Feng Yao (Southborough, Massachusetts) |
ABSTRACT | The present invention is directed to Herpes simplex-2 viruses that may be used in vaccines to immunize patients against genital herpes. |
FILED | Friday, February 01, 2019 |
APPL NO | 16/967275 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/245 (20130101) A61K 2039/5254 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/22 (20180101) Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/16621 (20130101) C12N 2710/16622 (20130101) C12N 2710/16634 (20130101) C12N 2710/16662 (20130101) C12N 2710/16671 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390651 | Lenouen et al. |
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FUNDED BY |
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APPLICANT(S) | THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland); CODAGENIX, INC. (Farmingdale, New York) |
ASSIGNEE(S) | The USA, Secretary, DHHS (Bethesda, Maryland); Codagenix, Inc. (Stony Brook, New York) |
INVENTOR(S) | Cyril Lenouen (Bethesda, Maryland); Ursula J. Buchholz (Silver Spring, Maryland); Peter L. Collins (Silver Spring, Maryland); Steffen Mueller (Stony Brook, New York) |
ABSTRACT | Reported herein are presumptively de-attenuating mutations that are useful, either individually or in combinations that may include other known mutations, in producing recombinant strains of human respiratory syncytial virus (RSV) exhibiting attenuation phenotypes. Also described herein is a novel RSV construct, Min_L-NPM2-1(N88K)L, which exhibits an attenuated phenotype, is stable and is as immunogenic as wild type RSV. The recombinant RSV strains described here are suitable for use as live-attenuated RSV vaccines. Exemplary vaccine candidates are described. Also provided are polynucleotide sequences capable of encoding the described viruses, as well as methods for producing and using the viruses. |
FILED | Monday, August 31, 2020 |
APPL NO | 17/008025 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0043 (20130101) A61K 39/155 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/20 (20180101) Peptides C07K 14/08 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/04 (20130101) C12N 2760/00021 (20130101) C12N 2760/00034 (20130101) C12N 2760/00062 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390662 | Raines et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
INVENTOR(S) | Ronald T. Raines (Cambridge, Massachusetts); Matthew D. Shoulders (Cambridge, Massachusetts); Jonathan A. Hodges (Durham, North Carolina) |
ABSTRACT | Novel collagen mimics are disclosed with a tripeptide unit having the formula (Xaa-Yaa-Gly)n, where one of the positions Xaa or Yaa is a bulky, non-electron withdrawing proline derivative. By substituting a proline derivative at either the Xaa or Yaa position in the native collagen helix, the stability of the helix is increased due solely to steric effects relative to prior known collagen-related triple helices. Methods are also disclosed for making the novel collagen mimics. |
FILED | Friday, June 21, 2019 |
APPL NO | 16/448750 |
ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Peptides C07K 5/0821 (20130101) C07K 14/001 (20130101) C07K 14/78 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390665 | Smider et al. |
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FUNDED BY |
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APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
INVENTOR(S) | Vaughn Smider (San Diego, California); Omar A. Bazirgan (San Diego, California); Hongyuan Helen Mao (San Diego, California); Peter Schultz (La Jolla, California); Feng Wang (Beijing, China PRC); Yong Zhang (Los Angeles, California) |
ABSTRACT | Disclosed herein are immunoglobulin constructs comprising at least one immunoglobulin domain or fragment thereof; and a therapeutic polypeptide or derivative or variant thereof attached to or inserted into said immunoglobulin domain. Also provided are immunoglobulin constructs comprising a mammalian immunoglobulin heavy chain comprising at least a portion of a knob domain in the complementarity-determining region 3 (CDR3H) or fragment thereof; and a therapeutic polypeptide attached to or inserted into said knob domain of the CDR3H. Also provided are immunoglobulin constructs comprising a mammalian immunoglobulin heavy chain comprising at least a portion of a stalk domain in the complementarity-determining region 3 (CDR3H) or fragment thereof; and a therapeutic polypeptide attached to or inserted into said stalk domain of the CDR3H. Also described herein are methods and compositions comprising the immunoglobulin constructs described herein for treatment and prevention of a disease or condition in a subject. |
FILED | Tuesday, January 14, 2020 |
APPL NO | 16/742759 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Peptides C07K 14/53 (20130101) C07K 16/00 (20130101) C07K 16/10 (20130101) Original (OR) Class C07K 16/46 (20130101) C07K 2317/20 (20130101) C07K 2317/50 (20130101) C07K 2317/55 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) C07K 2317/94 (20130101) C07K 2317/565 (20130101) C07K 2317/569 (20130101) C07K 2318/00 (20130101) C07K 2319/00 (20130101) C07K 2319/30 (20130101) C07K 2319/50 (20130101) C07K 2319/55 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/00 (20130101) C12N 15/09 (20130101) C12N 15/62 (20130101) C12N 15/63 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390667 | Bennett et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado); The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); THE REGENTS OF THE UNIVERSITY OF COLORAD (Denver, Colorado) |
INVENTOR(S) | Jeffery L. Bennett (Aurora, Colorado); Gregory P. Owens (Aurora, Colorado); Alan S. Verkman (San Francisco, California) |
ABSTRACT | The present invention is directed to antibodies binding to aquaporin 4 (AQP4) and methods of using such antibodies to treat neuromyelitis optica (NMO) either as a monotherapy or in combination with standard NMO therapies such as immunosuppressives or plasmaphersis. |
FILED | Monday, May 18, 2020 |
APPL NO | 16/877103 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/3955 (20130101) A61K 45/06 (20130101) Peptides C07K 16/18 (20130101) Original (OR) Class C07K 16/28 (20130101) C07K 2317/21 (20130101) C07K 2317/71 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/732 (20130101) C07K 2317/734 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390683 | Pastan et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
INVENTOR(S) | Ira H. Pastan (Chevy Chase, Maryland); Masanori Onda (Germantown, Maryland); Tapan Bera (Frederick, Maryland); Mitchell Ho (Urbana, Maryland) |
ABSTRACT | Polypeptides and proteins that specifically bind to and immunologically recognize human mesothelin582-598 (IP-NGYLVLDLSMQEALS) (SEQ ID NO: 1) are disclosed. Anti-mesothelin binding moieties, nucleic acids, recombinant expression vectors, host cells, populations of cells, pharmaceutical compositions, and conjugates relating to the polypeptides and proteins are disclosed. Methods of reducing mesothelin shed from cell membranes, methods of reducing the activity of TNFα converting enzyme, methods of detecting the presence of cancer, and methods of treating or preventing cancer are also disclosed. |
FILED | Thursday, May 17, 2018 |
APPL NO | 16/613971 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/395 (20130101) A61K 47/6829 (20170801) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/30 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) C12N 2800/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390684 | Mollick et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Joseph A. Mollick (Palo Alto, California); Pearline Teo (Singapore, Singapore); Paul J. Utz (Stanford, California) |
ABSTRACT | The present invention provides novel IgE antibodies useful for inhibiting or preventing metastatic cancer. Also provided are methods to inhibit tumor metastasis by modulating the activity of at least one non-tumor cell, treating a patient to inhibit or prevent tumor metastases of a primary solid tumor, treating metastatic carcinoma, reducing metastasis of carcinoma cells, and reducing the growth kinetics of a primary solid tumor or a metastasized cell or tumor. |
FILED | Monday, October 14, 2019 |
APPL NO | 16/600762 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/2887 (20130101) C07K 16/3092 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/52 (20130101) C07K 2317/56 (20130101) C07K 2317/70 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390721 | Alexanian et al. |
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FUNDED BY |
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APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
INVENTOR(S) | Erik Alexanian (Chapel Hill, North Carolina); Frank Albert Leibfarth (Carrboro, North Carolina); Jill Williamson (Chapel Hill, North Carolina); Will Czaplyski (Cambridge, Massachusetts) |
ABSTRACT | The subject matter described herein relates to methods for polymer xanthylation and the xanthylated polymers produced by such methods. Subsequent replacement of the xanthylate moiety allows facile entry into functionalized polymers. |
FILED | Wednesday, October 03, 2018 |
APPL NO | 16/753390 |
ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 10/02 (20130101) C08F 10/06 (20130101) C08F 10/10 (20130101) C08F 2810/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/912 (20130101) C08G 64/42 (20130101) C08G 65/3348 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 7/12 (20130101) Original (OR) Class C08J 2323/26 (20130101) C08J 2323/36 (20130101) C08J 2367/04 (20130101) C08J 2369/00 (20130101) C08J 2371/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390848 | Blazar et al. |
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FUNDED BY |
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APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota); Regents of the University of Michigan (Ann Arbor, Michigan); The Ohio State University (Columbus, Ohio) |
INVENTOR(S) | Bruce R. Blazar (Golden Valley, Minnesota); Keli Hippen (Minneapolis, Minnesota); Pavan Reddy (Ann Arbor, Michigan); Yaping Sun (Ann Arbor, Michigan); Ramiro Garzon (Columbus, Ohio) |
ABSTRACT | This disclosure provides miRNA/mRNA pairs that can be used to increase the efficacy of T cells or to down-modulate T cell efficacy and restore equilibrium. |
FILED | Wednesday, June 28, 2017 |
APPL NO | 16/314141 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/06 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Original (OR) Class C12N 5/0637 (20130101) C12N 15/113 (20130101) C12N 2310/113 (20130101) C12N 2320/32 (20130101) C12N 2501/65 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390852 | Ghaedi et al. |
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FUNDED BY |
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APPLICANT(S) | Yale University (New Haven, Connecticut) |
ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
INVENTOR(S) | Mahboobe Ghaedi (New Haven, Connecticut); Laura Niklason (Greenwich, Connecticut) |
ABSTRACT | The present invention provides compositions and methods of preparing airway cells. In one aspect, an epithelial airway cell derived from an induced pluripotent stem (iPS) cell characterized by expression of airway cell surface markers and an ability to proliferate is described. In another aspect, methods of differentiating an iPS into an epithelial airway cell is provided. Engineered lungs, methods of making such engineered lungs comprising the epithelial airway cells and treating respiratory disorders are also disclosed. |
FILED | Wednesday, January 14, 2015 |
APPL NO | 15/100978 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/36 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0688 (20130101) Original (OR) Class C12N 5/0689 (20130101) C12N 2500/99 (20130101) C12N 2501/15 (20130101) C12N 2501/115 (20130101) C12N 2501/155 (20130101) C12N 2501/415 (20130101) C12N 2506/45 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390853 | Pokorski et al. |
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FUNDED BY |
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APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
INVENTOR(S) | Jonathan Pokorski (San Diego, California); Nicole Steinmetz (San Diego, California); Parker Lee (Los Angeles, California) |
ABSTRACT | A method of producing plant virus-like particles includes freeze drying an aqueous solution of plant virus particles to produce a substantially RNA-free plant virus-like particles. |
FILED | Monday, April 27, 2020 |
APPL NO | 16/859400 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 2770/18023 (20130101) C12N 2770/18051 (20130101) C12N 2770/32023 (20130101) C12N 2770/32051 (20130101) Enzymes C12Y 301/27005 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390861 | Friedland et al. |
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FUNDED BY |
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APPLICANT(S) | EDITAS MEDICINE, INC. (Cambridge, Massachusetts); DUKE UNIVERSITY (Durham, North Carolina) |
ASSIGNEE(S) | EDITAS MEDICINE, INC. (Cambridge, Massachusetts); DUKE UNIVERSITY (Durham, North Carolina) |
INVENTOR(S) | Ari E. Friedland (Boston, Massachusetts); Penrose O'Donnell (Yarmouth, Massachusetts); David A. Bumcrot (Belmont, Massachusetts); Bryan R. Cullen (Durham, North Carolina) |
ABSTRACT | Genome editing systems and genetic constructs that target a herpes simplex virus (HSV) viral gene, where the systems comprise one Cas9 molecule, and a gRNA molecule, compositions and cells comprising such genome editing systems and genetic constructs as well as methods for using the genome editing systems, genetic constructs, compositions and cells for genome engineering, and for preventing, treating or reducing HSV infection. |
FILED | Friday, April 26, 2019 |
APPL NO | 16/395833 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 15/11 (20130101) C12N 15/1133 (20130101) C12N 2310/20 (20170501) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390882 | Stankey et al. |
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FUNDED BY |
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APPLICANT(S) | VARIGEN BIOSCIENCES CORPORATION (Middleton, Wisconsin) |
ASSIGNEE(S) | VARIGEN BIOSCIENCES CORPORATION (Middleton, Wisconsin) |
INVENTOR(S) | Robert Joseph Stankey (Madison, Wisconsin); David Mead (Middleton, Wisconsin) |
ABSTRACT | Disclosed herein are recombinant methods of activating expression of one or more biosynthetic gene clusters comprising more than one gene, the method comprising a recombinant DNA expression vector that possess two opposable inducible promoters that drives expression of a biosynthetic gene cluster exogenously from outside of the cluster to produce polyketides or non-ribosomal peptides in a heterologous host. |
FILED | Wednesday, March 11, 2020 |
APPL NO | 16/815399 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/52 (20130101) C12N 15/70 (20130101) C12N 15/86 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390883 | Gao et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Guangping Gao (Westborough, Massachusetts); James M. Wilson (Philadelphia, Pennsylvania); Mauricio R. Alvira (Philadelphia, Pennsylvania) |
ABSTRACT | Sequences of a serotype 8 adeno-associated virus and vectors and host cells containing these sequences are provided. Also described are methods of using such host cells and vectors in production of rAAV particles. |
FILED | Friday, October 01, 2021 |
APPL NO | 17/492229 |
ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 35/761 (20130101) A61K 38/45 (20130101) A61K 38/177 (20130101) A61K 38/4846 (20130101) A61K 48/00 (20130101) Peptides C07K 14/005 (20130101) C07K 14/705 (20130101) C07K 14/755 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 9/644 (20130101) C12N 9/1018 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 15/8645 (20130101) C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) C12N 2750/14152 (20130101) C12N 2830/008 (20130101) C12N 2830/48 (20130101) C12N 2830/85 (20130101) Enzymes C12Y 201/03003 (20130101) C12Y 304/21021 (20130101) C12Y 304/21022 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390885 | Zhang et al. |
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FUNDED BY |
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APPLICANT(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
ASSIGNEE(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
INVENTOR(S) | Yi Zhang (Newton, Massachusetts); Shogo Matoba (Brookline, Massachusetts) |
ABSTRACT | The present invention provides methods and compostions to improve the efficiency of somatic cell nuclear transfer (SCNT) and the consequent production of nuclear transfer ESC (ntESC) and transgenic cells and/or non-human animals. More specifically, the present invention relates to the discovery that trimethylation of Histone H3-Lysine 9 (H3K9me3) in reprogramming resistant regions (RRRs) in the nuclear genetic material of donor somatic cells prevents efficient somatic cell nuclear reprogramming or SCNT. The present invention provide methods and compositions to decrease H3K9me3 in methods to improve efficacy of SCNT by exogenous or overexpression of the demethylase Kdm4 family and/or inhibiting methylation of H3K9me3 by inhibiting the histone methyltransferases Suv39h1 and/or Suv39h2. |
FILED | Tuesday, September 15, 2015 |
APPL NO | 15/511348 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0273 (20130101) A01K 2227/105 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0604 (20130101) C12N 5/0606 (20130101) C12N 15/877 (20130101) Original (OR) Class C12N 15/1137 (20130101) C12N 2310/14 (20130101) C12N 2517/04 (20130101) Enzymes C12Y 201/01043 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390908 | Pederson et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts); University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
ASSIGNEE(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts); UNIVERSITY OF CENTRAL FLORIDA FOUNDATION, INC. (Orlando, Florida) |
INVENTOR(S) | Thoru Pederson (Worcester, Massachusetts); Hanhui Ma (Shrewsbury, Massachusetts); Li-Chun Tu (Worcester, Massachusetts); Ardalan Naseri (Orlando, Florida); Maximilaan Huisman (Worcester, Massachusetts); Shaojie Zhang (Orlando, Florida) |
ABSTRACT | A C9orf72 DNA repeat expansion can be detected using a CRISPR Arrayed Repeat Detection System (CARDS). Based upon the compositions and methods supporting this platform primary cell cultures and/or blood cell smears can be tested under conventional clinical diagnostic laboratory conditions to diagnose genetically-based diseases having DNA repeat expansions, including but not limited to ALS. dCas9 constructs are also contemplated as having fluorescent proteins bound to any or all stem loop sequences, wherein detection of a plurality of dCas9 constructs having different colored fluorescent proteins can simultaneously detect at least six (6) different gene target loci. |
FILED | Thursday, September 01, 2016 |
APPL NO | 15/757240 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/85 (20130101) C12N 2310/20 (20170501) C12N 2310/3519 (20130101) C12N 2830/003 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) Original (OR) Class C12Q 1/6816 (20130101) C12Q 2521/507 (20130101) C12Q 2563/107 (20130101) C12Q 2563/119 (20130101) C12Q 2600/156 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390918 | Quake et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Stephen R. Quake (Stanford, California); Thomas M. Snyder (Palo Alto, California); Hannah Valantine (Stanford, California) |
ABSTRACT | The invention provides methods, devices, compositions and kits for diagnosing or predicting transplant status or outcome in a subject who has received a transplant. |
FILED | Tuesday, May 18, 2021 |
APPL NO | 17/323917 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class C12Q 1/6837 (20130101) C12Q 1/6869 (20130101) C12Q 1/6883 (20130101) C12Q 2600/106 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) G16B 20/20 (20190201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390923 | Chinnaiyan et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
INVENTOR(S) | Arul Chinnaiyan (Plymouth, Michigan); John Prensner (Ann Arbor, Michigan); Matthew Iyer (Ann Arbor, Michigan) |
ABSTRACT | The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to ncRNAs as diagnostic markers and clinical targets for prostate, lung, breast and pancreatic cancer. |
FILED | Wednesday, June 26, 2019 |
APPL NO | 16/453195 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11391268 | Han et al. |
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FUNDED BY |
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APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Jooli Han (Pittsburgh, Pennsylvania); Dennis Robert Trumble (Pittsburgh, Pennsylvania) |
ABSTRACT | A muscle-powered pulsation device for cardiac support including a muscle energy converter device including a piston arrangement for directing fluid out of an outlet of the muscle energy converter device using energy provided by a patient's muscle, and a hydraulic volume amplification device fluidly connected to the muscle energy converter device. The volume amplification device includes a casing including an inlet and an outlet, the inlet in fluid communication with the outlet of the muscle energy converter device, at least one resilient member positioned within an interior cavity defined by the casing, and at least one piston member movably and sealingly positioned within the interior cavity of the casing and operatively connected to the at least one resilient member, the at least one piston member separating the interior cavity into a first chamber and a second chamber. |
FILED | Tuesday, June 19, 2018 |
APPL NO | 16/617706 |
ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 60/40 (20210101) A61M 60/148 (20210101) A61M 60/268 (20210101) Positive-displacement Machines for Liquids; Pumps F04B 9/107 (20130101) Original (OR) Class F04B 43/067 (20130101) F04B 45/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11391726 | Lake et al. |
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FUNDED BY |
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APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona); MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (Rochester, Minnesota) |
ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona); MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (Rochester, Minnesota) |
INVENTOR(S) | Douglas Lake (Scottsdale, Arizona); Thai H. Ho (Scottsdale, Arizona); Glen J. Weiss (Phoenix, Arizona) |
ABSTRACT | The present invention includes a method for screening one or more agents that modulate Regulatory T cell (Treg) activity, the method comprising the steps of: incubating a population CD4+ cells isolated from human blood peripheral mononuclear cells the CD4+ cells in contact with MoT cells in the presence of the one or more agents suspected of modulating Treg activity; detecting activation of the CD4+ cells without or with the agent; and comparing the activation of the CD4+ cells without or with the agent, wherein a change in activation following incubation with the agent relative to the activation of the PBMCs following incubation without the agent indicates that the agent is a modulator of Treg activity. |
FILED | Wednesday, September 25, 2019 |
APPL NO | 17/256592 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0637 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/505 (20130101) Original (OR) Class G01N 2500/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11391729 | Bergo |
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FUNDED BY |
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APPLICANT(S) | Adeptrix Corp. (Beverly, Massachusetts) |
ASSIGNEE(S) | ADEPTRIX CORP. (Beverly, Massachusetts) |
INVENTOR(S) | Vladislav B. Bergo (Boston, Massachusetts) |
ABSTRACT | Bead arrays suitable for analysis by mass spectrometry are disclosed. In an embodiment, a bead array includes multiple reactive sites, each of the reactive sites being capable of binding multiple distinct target analytes. |
FILED | Friday, September 07, 2018 |
APPL NO | 16/125164 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/745 (20130101) G01N 33/6845 (20130101) G01N 33/6848 (20130101) G01N 33/6854 (20130101) G01N 33/54306 (20130101) Original (OR) Class G01N 33/54313 (20130101) G01N 2440/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11391739 | Carrasco et al. |
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FUNDED BY |
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APPLICANT(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
INVENTOR(S) | Ruben Carrasco (Brookline, Massachusetts); Di Zhu (Newton, Massachusetts) |
ABSTRACT | Provided by the invention are methods for identifying therapeutic agents for treating multiple myeloma or another hematological malignancy, as well as methods for determining the prognosis of a patient with multiple myeloma or another hematological malignancy. The methods are based in part on the inventors' discovery that an extracellular form of cyclophilin A binds to CD147 expressed on multiple myeloma cells. |
FILED | Friday, June 14, 2019 |
APPL NO | 16/441166 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/118 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57407 (20130101) Original (OR) Class G01N 2333/99 (20130101) G01N 2333/70596 (20130101) G01N 2500/02 (20130101) G01N 2800/52 (20130101) G01N 2800/56 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11391740 | Huang |
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FUNDED BY |
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APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
INVENTOR(S) | Haojie Huang (Rochester, Minnesota) |
ABSTRACT | This document provides methods and materials involved in identifying and/or treating mammals having a treatment-resistant prostate cancer (e.g., an enzalutamide-resistant, castration-resistant prostate cancer). For example, methods and materials for identifying a mammal (e.g., a human) having treatment-resistant prostate cancer (e.g., an enzalutamide-resistant, castration-resistant prostate cancer) as having an elevated level of one or more polypeptides (e.g., one or more of a CXXC5, a CXXC4, a TET2, an ID1, an ID3, and/or a PFN2 polypeptide) in treatment-resistant prostate tissue are provided. Methods and materials for administering one or more targeted therapies with or without one or more chemotherapeutic agents to a mammal having treatment-resistant prostate cancer identified as having an elevated level of one or more polypeptides (e.g., one or more of a CXXC5, a CXXC4, a TET2, an ID1, an ID3, and/or a PFN2 polypeptide) in treatment-resistant prostate tissue also are provided. |
FILED | Tuesday, May 19, 2020 |
APPL NO | 16/878244 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/551 (20130101) A61K 45/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57434 (20130101) Original (OR) Class G01N 2333/4703 (20130101) G01N 2333/90245 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11391803 | Bilgic et al. |
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FUNDED BY |
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APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | Berkin Bilgic (Boston, Massachusetts); Sohyun Han (Cambridge, Massachusetts); Stephen F. Cauley (Cambridge, Massachusetts); Lawrence L. Wald (Cambridge, Massachusetts); Kawin Setsompop (Charleston, Massachusetts) |
ABSTRACT | Systems and methods are provided for improving MRI data acquisition efficiency while providing more detailed information with high resolution and isotropic resolution without gaps. Improved data acquisition efficiency may be achieved by implementing a machine learning algorithm with a hardware processor and a memory to estimate imperfections in fast imaging sequences, such as a multi-shot echo planar imaging (MS-EPI) sequence. These imperfections, such as patient motion, physiological noise, and phase variations, may be difficult to model or otherwise estimate using standard physics-based reconstructions. |
FILED | Monday, March 04, 2019 |
APPL NO | 16/976997 |
ART UNIT | 2852 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5608 (20130101) G01R 33/5616 (20130101) G01R 33/56509 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) Image Data Processing or Generation, in General G06T 11/008 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11392016 | Grunwald et al. |
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FUNDED BY |
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APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
INVENTOR(S) | David Grunwald (Worcester, Massachusetts); Maximiliaan Huisman (Brookfield, Massachusetts); Carlas Smith (Delft, Netherlands) |
ABSTRACT | The described embodiments are directed to a system and methods of calibrating a fluorescence microscope and/or light detection device using a calibrating apparatus. The apparatus may comprise a main body housing, a sensor head, and a microcontroller assembly disposed within the housing. The housing may include an adapter to mechanically couple the housing to a microscope. The sensor head may comprise (i) an optical power sensor to produce a power signal representative of an optical power magnitude of light applied to the optical power sensor, (ii) an optical wavelength sensor configured to produce wavelength information associated with the light applied to the optical wavelength sensor, and (iii) a light source configured to direct light toward a detection device associated with the microscope. The microcontroller assembly may be configured to generate an optical power magnitude value based on the power signal and adjusted according to the wavelength information. |
FILED | Tuesday, October 13, 2020 |
APPL NO | 17/069335 |
ART UNIT | 2878 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/008 (20130101) G02B 21/0032 (20130101) G02B 21/361 (20130101) G02B 21/362 (20130101) Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor G03B 21/204 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11393087 | Parikh et al. |
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FUNDED BY |
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APPLICANT(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
ASSIGNEE(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
INVENTOR(S) | Nehal Parikh (Cincinnati, Ohio); Lili He (Cincinnati, Ohio) |
ABSTRACT | A system for objectively analyzing medical image data for the presence of diffuse white matter abnormalities (DWMA) is configured to identify and determine DWMA characteristics that are not visually apparent. As compared to subjective visual diagnosis, objectively determined DWMA characteristics may be automatically compared to each other, and may be compared to and associated with various scales, evaluations, or other assessment criteria used to measure aspects of infant development. As a result, the disclosed system may objectively determine an impact that objectively determined DWMA characteristics will have on one or more developmental scales, which can be expressed as a time deficit, score deficit, or other value indicative of development deficits. The system may be integrated with medical imaging devices to provide near-immediate objective analysis for developmental impact at the point of care and in parallel with conventional imaging tasks, or may provide objective analysis results via a software interface. |
FILED | Thursday, March 19, 2020 |
APPL NO | 16/823827 |
ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 2207/10088 (20130101) G06T 2207/30016 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11393614 | Mine et al. |
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FUNDED BY |
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APPLICANT(S) | General Electric Company (Schenectady, New York) |
ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
INVENTOR(S) | Susumu Mine (Niskayuna, New York); Minfeng Xu (Ballston Lake, New York); Anbo Wu (Clifton Park, New York); Paul St. Mark Shadforth Thompson (Stephentown, New York) |
ABSTRACT | A current lead assembly for minimizing heat load to a conduction cooled superconducting magnet during a ramp operation is provided. The current lead assembly includes a vacuum chamber having a through hole to enable a first end of a current lead contact to remain outside the vacuum chamber and a second end of the current lead contact to penetrate within the vacuum chamber. A vacuum boundary wall is located between the vacuum chamber and the current lead contact. At least one superconducting magnet is arranged inside of the vacuum chamber and includes a magnet lead. A second end of the current lead contact is coupled to the magnet lead via an internal lead. A vacuum cap is removably disposed to sealingly encompass therein the first end of the current lead contact during a first state of operation. The first end of the current lead contact is arranged to contact a power supply during a second state of operation, wherein the contact occurs exterior the vacuum chamber. |
FILED | Friday, February 28, 2020 |
APPL NO | 16/804645 |
ART UNIT | 2837 — Electrical Circuits and Systems |
CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 6/04 (20130101) H01F 6/008 (20130101) Original (OR) Class Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 4/68 (20130101) Installation of Electric Cables or Lines, or of Combined Optical and Electric Cables or Lines H02G 15/34 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11393974 | Agarwal et al. |
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FUNDED BY |
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APPLICANT(S) | Signal Solutions, LLC (Lexington, Kentucky) |
ASSIGNEE(S) | Signal Solutions, LLC (Lexington, Kentucky) |
INVENTOR(S) | Anuj Agarwal (Lexington, Kentucky); Michael E. Lhamon (Lexington, Kentucky) |
ABSTRACT | Sensing an environment by confining a monitored live subject in an enclosure, detecting an effect on a coaxial piezoelectric cable resulting from the monitored live subject, wherein the coaxial piezoelectric cable is located at least proximate to the enclosure, and deriving information about a state of the monitored live subject based on the detected effect. |
FILED | Tuesday, October 13, 2020 |
APPL NO | 17/069419 |
ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 29/005 (20130101) Diagnosis; Surgery; Identification A61B 5/113 (20130101) A61B 5/0816 (20130101) A61B 5/4812 (20130101) A61B 5/4818 (20130101) A61B 5/6888 (20130101) A61B 5/6892 (20130101) A61B 2503/40 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/45 (20130101) Original (OR) Class H01L 41/087 (20130101) H01L 41/193 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
US 11388945 | Snow et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Arlington, Virginia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Keyport, Washington) |
INVENTOR(S) | Jacob Snow (Bremerton, Washington); Jacob Yates (Poulsbo, Washington); Nathan Schuyler (Silverdale, Washington) |
ABSTRACT | A face shield for use with protective headgear can be shipped flat and easily assembled from a kit of parts without the use of tools or adhesives. The face shield protects against disease, aerosols and splatter that may contain pathogens; may include a curved lower perimeter to facilitate head movements, and can be taken on and off easily. |
FILED | Friday, September 25, 2020 |
APPL NO | 16/974092 |
ART UNIT | 3732 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Hats; Head Coverings A42B 3/18 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389069 | Grudic et al. |
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FUNDED BY |
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APPLICANT(S) | Flashback Technologies, Inc. (Boulder, Colorado); The Regents of the University of Colorado (Denver, Colorado) |
ASSIGNEE(S) | Flashback Technologies, Inc. (Westfield, New Jersey); The Regents of the University of Colorado (Denver, Colorado) |
INVENTOR(S) | Gregory Zlatko Grudic (Niwot, Colorado); Steven L. Moulton (Littleton, Colorado); Isobel Jane Mulligan (Niwot, Colorado) |
ABSTRACT | Tools and techniques for estimating a probability that a patient is bleeding or has sustained intravascular volume loss (e.g., due to hemodialysis or dehydration) and/or to estimate a patient's current hemodynamic reserve index, track the patient's hemodynamic reserve index over time, and/or predict a patient's hemodynamic reserve index in the future. Tools and techniques for estimating and/or predicting a patient's dehydration state. Tools and techniques for controlling a hemodialysis machine based on the patient's estimated and/or predicted hemodynamic reserve index. |
FILED | Thursday, July 13, 2017 |
APPL NO | 15/649411 |
ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/021 (20130101) A61B 5/029 (20130101) A61B 5/318 (20210101) A61B 5/02028 (20130101) Original (OR) Class A61B 5/02042 (20130101) A61B 5/7275 (20130101) A61B 5/14551 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/60 (20180101) G16H 50/30 (20180101) Technologies for Adaptation to Climate Change Y02A 90/10 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389168 | Greene, Jr. et al. |
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FUNDED BY |
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APPLICANT(S) | MicroVention, Inc. (Tustin, California); University of Virginia Patent Foundation (Charlottesville, Virginia); United States of America as Represented by the Secretary of the Navy (Silver Spring, Maryland) |
ASSIGNEE(S) | MicroVention, Inc. (Aliso Viejo, California); University of Virginia Patent Foundation (Charlottesville, Virginia); United States of America as Represented by the Secretary of the Navy (Silver Spring, Maryland) |
INVENTOR(S) | George R. Greene, Jr. (Costa Mesa, California); Ivan Sepetka (Los Altos, California); Cathy Lei (Chino Hills, California); Rupal Nguyen (Costa Mesa, California); Matthew J. Bradley (Silver Spring, Maryland); Stephen T. Ahlers (Silver Spring, Maryland); Carl S. Goforth (Silver Spring, Maryland); James R. Stone (Charlottesville, Virginia) |
ABSTRACT | A temporary aortic occlusion device is disclosed, having an expandable locator portion and an expandable occlusion portion. The expandable locator portion assists a user in determining whether the distal end of the device has been advanced within a patient's aorta, and the occlusion portion is expanded to occlude the patient's aorta, preferably below the renal arteries. |
FILED | Tuesday, August 29, 2017 |
APPL NO | 15/690152 |
ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/1204 (20130101) A61B 17/12109 (20130101) Original (OR) Class A61B 17/12136 (20130101) A61B 17/12168 (20130101) A61B 17/12172 (20130101) A61B 17/12177 (20130101) A61B 2017/00115 (20130101) A61B 2017/1205 (20130101) A61B 2090/0807 (20160201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389169 | Greene, Jr. et al. |
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FUNDED BY |
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APPLICANT(S) | MicroVention, Inc. (Tustin, California); University of Virginia Patent Foundation (Charlottesville, Virginia); United States of America As Represented By The Secretary Of The Navy (Silver Spring, Maryland) |
ASSIGNEE(S) | Microvention, Inc. (Tustin, California); University of Virginia Patent Foundation (Charlottesville, Virginia); United States of America as Represented by the Secretary of the Navy (Silver Spring, Maryland) |
INVENTOR(S) | George R. Greene, Jr. (Costa Mesa, California); Ivan Sepetka (Los Altos, California); Cathy Lei (Chino Hills, California); Rupal Nguyen (Costa Mesa, California); Matthew J. Bradley (Silver Spring, Maryland); Stephen T. Ahlers (Silver Spring, Maryland); Carl W. Goforth (Silver Spring, Maryland); James R. Stone (Charlottesville, Virginia) |
ABSTRACT | A temporary aortic occlusion device is disclosed, having an expandable locator portion and an expandable occlusion portion. The expandable locator portion assists a user in determining whether the distal end of the device has been advanced within a patient's aorta, and the occlusion portion is expanded to occlude the patient's aorta, preferably below the renal arteries. |
FILED | Thursday, February 28, 2019 |
APPL NO | 16/289485 |
ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/1204 (20130101) A61B 17/1214 (20130101) A61B 17/12109 (20130101) Original (OR) Class A61B 17/12136 (20130101) A61B 17/12172 (20130101) A61B 17/12177 (20130101) A61B 2017/00942 (20130101) A61B 2017/1205 (20130101) A61B 2090/0807 (20160201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389400 | Batchinsky et al. |
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FUNDED BY |
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APPLICANT(S) | Qool Therapeutics, Inc. (Menlo Park, California) |
ASSIGNEE(S) | The Government of The United States, as Represented by The Secretary of the Army (Fort Detrick, Maryland) |
INVENTOR(S) | Andriy Batchinsky (San Antonio, Texas); Ben Antebi (Helotes, Texas); Brendan M. Beely (San Antonio, Texas); Leopoldo C. Cancio (San Antonio, Texas); Amir Belson (Savyon, Israel); Beverly Huss (Menlo Park, California); Edward J. Hayes (San Jose, California); Jeff G. Haydon (Menlo Park, California) |
ABSTRACT | A treatment system delivers a breathing gas and frozen stem cells or other biologic particles (FBP) to a bronchus of a lung of a patient in order to treat lung and other conditions. The breathing gas and the FBP are usually delivered through separate lumens. The FBP may be delivered concurrently with other frozen particles, such as frozen saline particles (FSP). The FBP/FSP will remain frozen at all times from preparation to delivery, and will thaw only after they are released into the lung. |
FILED | Wednesday, July 25, 2018 |
APPL NO | 16/045046 |
ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 7/00 (20130101) A61F 7/12 (20130101) A61F 2007/0064 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0075 (20130101) Original (OR) Class A61K 9/0078 (20130101) A61K 35/28 (20130101) A61K 35/50 (20130101) A61K 35/545 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 11/00 (20130101) A61M 11/001 (20140204) A61M 16/14 (20130101) A61M 16/201 (20140204) A61M 2202/064 (20130101) A61M 2202/0437 (20130101) A61M 2205/366 (20130101) A61M 2205/3368 (20130101) A61M 2205/3606 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389484 | Aggarwal et al. |
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FUNDED BY |
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APPLICANT(S) | Mesoblast International Sarl (Meyrin, Switzerland) |
ASSIGNEE(S) | Mesoblast International Sárl (Meyrin, Switzerland) |
INVENTOR(S) | Sudeepta Aggarwal (North Potomac, Maryland); Mark F. Pittenger (Severna Park, Maryland); Timothy Varney (Baltimore, Maryland) |
ABSTRACT | Compositions and methods of promoting wound healing in a human by administering to the human mesenchymal stem cells in an effective amount. |
FILED | Monday, December 10, 2018 |
APPL NO | 16/214485 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Original (OR) Class A61K 38/2026 (20130101) A61K 38/2066 (20130101) A61K 45/06 (20130101) A61K 2035/124 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0662 (20130101) C12N 5/0663 (20130101) C12N 5/0664 (20130101) C12N 5/0665 (20130101) C12N 5/0666 (20130101) C12N 5/0667 (20130101) C12N 5/0668 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389532 | Clark et al. |
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APPLICANT(S) | University of Washington (Seattle, Washington) |
ASSIGNEE(S) | University of Washington (Seattle, Washington); Abacus Bioscience, Inc. (Sammamish, Washington) |
INVENTOR(S) | Edward A. Clark (Seattle, Washington); Che-Leung Law (Seattle, Washington); Deborah Fuller (Seattle, Washington); Michael Gale (Seattle, Washington) |
ABSTRACT | Compositions including a CD180 binding ligand and a linked Hepatitis B antigen and their use are disclosed. The Hepatitis B antigen includes Hepatitis B virus pre-S1 and/or pre-S2 region of the HBV envelope protein (HBVpreS1/S2Ag), L-HBsAg, MHBsAg, S-HBsAg, or antigenic fragments or mutants thereof. |
FILED | Thursday, November 15, 2018 |
APPL NO | 16/764950 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/292 (20130101) Original (OR) Class A61K 2039/6056 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/20 (20180101) Peptides C07K 16/2878 (20130101) C07K 16/2896 (20130101) C07K 2317/56 (20130101) C07K 2317/524 (20130101) C07K 2317/526 (20130101) C07K 2317/622 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389866 | Rosi et al. |
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APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Nathaniel L. Rosi (Pittsburgh, Pennsylvania); Andrea David Merg (Pittsburgh, Pennsylvania); Soumitra Punekar (Pittsburgh, Pennsylvania) |
ABSTRACT | Described herein are metal nanoparticle superstructures and methods and compounds for making the same. |
FILED | Thursday, December 14, 2017 |
APPL NO | 15/842625 |
ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/07 (20220101) Original (OR) Class B22F 1/054 (20220101) B22F 1/0553 (20220101) B22F 9/24 (20130101) B22F 2301/255 (20130101) Nanostructures Formed by Manipulation of Individual Atoms, Molecules, or Limited Collections of Atoms or Molecules as Discrete Units; Manufacture or Treatment Thereof B82B 3/0009 (20130101) B82B 3/0066 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 40/00 (20130101) Heterocyclic Compounds C07D 249/04 (20130101) Peptides C07K 7/08 (20130101) C07K 17/14 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390198 | Evans et al. |
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APPLICANT(S) | PRATT and MILLER ENGINEERING AND FABRICATION, INC. (New Hudson, Michigan) |
ASSIGNEE(S) | PRATT and MILLER ENGINEERING AND FABRICATION, LLC (New Hudson, Michigan) |
INVENTOR(S) | Celyn M. Evans (Milford, Michigan); Kevin R. Kwiatkowski (Ann Arbor, Michigan) |
ABSTRACT | A seat having a seat back pivotally connected to a seat pan, the seat back and the seat pan independently pivotal. At the pivot between the seat back and the seat pan there is a rotary energy attenuation device. The rotary energy attenuating device cooperates with a track system along the length of seat longitudinal members allowing for different directions of travel and height adjustment. The vehicle seat offers passive or active protection from impact and sudden acceleration due to accident or explosive events and is capable of automatically resetting. |
FILED | Wednesday, April 28, 2021 |
APPL NO | 17/243013 |
ART UNIT | 3636 — Static Structures, Supports and Furniture |
CURRENT CPC | Seats Specially Adapted for Vehicles; Vehicle Passenger Accommodation Not Otherwise Provided for B60N 2/4214 (20130101) B60N 2/42745 (20130101) Original (OR) Class B60N 2/42772 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390373 | Collmus et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | John P. Collmus (Camarillo, California); Nicholas J. Duckworth (Annapolis, Maryland); Scott M. Reider (Camarillo, California); Chong T. Oh (Camarillo, California) |
ABSTRACT | The embodiments are directed to an interface mount between a vehicle steering/control device and a mobile computer protective case. The interface mount has two sides. One side of the interface mount is attached to the vehicle steering/control device. The other side of the interface mount is attached to an AMPS hole pattern plate. |
FILED | Thursday, June 10, 2021 |
APPL NO | 17/343973 |
ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Aeroplanes; Helicopters B64C 13/0423 (20180101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390382 | Anderson et al. |
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APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
INVENTOR(S) | Michael Anderson (Colorado Springs, Colorado); Benjamin Stark (Dixon, California); Jeffrey Burnett (Severna Park, Maryland); Tyler Copien (San Angelo, Texas); Candice Roberts (Milford, Virginia) |
ABSTRACT | A system for deploying an unmanned aerial vehicle in a target region. The system includes a pod configured to be deployed from an air craft in a first region remote from the target region. The pod includes a capsule housing portion and a capsule ejection system in operative communication with the capsule housing portion. A capsule is dimensioned and configured to be disposed in the capsule housing portion as the pod is deployed from the aircraft and is ejected from the capsule housing portion by the capsule ejection system in a second region remote from the first region and the target region. The capsule includes a UAV housing portion dimensioned and configured to encase the unmanned aerial vehicle and a UAV ejection system in operative communication with the UAV housing portion for deploying the unmanned aerial vehicle in the target region. |
FILED | Monday, July 08, 2019 |
APPL NO | 16/504563 |
ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) Original (OR) Class B64C 2201/027 (20130101) B64C 2201/082 (20130101) B64C 2201/108 (20130101) B64C 2201/206 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 1/12 (20130101) B64D 5/00 (20130101) B64D 17/80 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390517 | Endean et al. |
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APPLICANT(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
ASSIGNEE(S) | Honeywell International Inc. (Charlotte, North Carolina) |
INVENTOR(S) | Daniel Endean (Plymouth, Minnesota); John Reinke (Plymouth, Minnesota) |
ABSTRACT | Systems and methods for suppressing bias in a non-degenerate vibratory structure are provided. In certain embodiments, a vibratory structure includes a first proof mass; a second proof mass, wherein the first proof mass and the second proof mass are driven into motion along a first axis, wherein the first proof mass and the second proof mass move in anti-phase along a second axis, wherein the motion of the first proof mass and the second proof mass along the second axis is such that the centers of mass of the first proof mass and the second proof mass move collinearly along a same axis. |
FILED | Tuesday, June 30, 2020 |
APPL NO | 16/917292 |
ART UNIT | 2861 — Printing/Measuring and Testing |
CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0021 (20130101) Original (OR) Class B81B 3/0072 (20130101) B81B 7/0058 (20130101) B81B 2201/0242 (20130101) B81B 2203/0118 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/574 (20130101) G01C 19/5719 (20130101) G01C 19/5747 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390636 | Chaloux et al. |
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APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Brian L. Chaloux (Alexandria, Virginia); Albert Epshteyn (Potomac, Maryland); Thomas J. Dabrow (College Park, Maryland) |
ABSTRACT | Described herein is the preparation of carbon phosphonitride pre-polymers that are soluble in organic solvents and can be further thermoset into carbon phosphonitride extended solids (i.e. films, monoliths, etc.) with an approximate empirical formula of C3N3P. |
FILED | Tuesday, July 27, 2021 |
APPL NO | 17/443750 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/5036 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390888 | Horwitz et al. |
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FUNDED BY |
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APPLICANT(S) | Amyris, Inc. (Emeryville, California) |
ASSIGNEE(S) | AMYRIS, INC. (Emeryville, California) |
INVENTOR(S) | Andrew Horwitz (Emeryville, California); Kristy Michelle Hawkins (Emeryville, California); Max Schubert (Emeryville, California); Wayne Szeto (Emeryville, California) |
ABSTRACT | Provided herein are methods of integrating one or more exogenous nucleic acids into one or more selected target sites of a host cell genome. in certain embodiments, the methods comprise contacting the host cell genome with one or more integration polynucleotides comprising an exogenous nucleic acid to be integrated into a genomic target site, a nuclease capable of causing a break at the genomic target site, and a linear nucleic acid capable of homologous recombination with itself or with one or more additional linear nucleic acids contacted with the population of cells, whereupon said homologous recombination results in formation of a circular extrachromosomal nucleic acid comprising a coding sequence for a selectable marker. in some embodiments, the methods further comprise selecting a host cell that expresses the selectable marker. |
FILED | Wednesday, March 11, 2020 |
APPL NO | 16/816172 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/902 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/20 (20170501) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6897 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390923 | Chinnaiyan et al. |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
INVENTOR(S) | Arul Chinnaiyan (Plymouth, Michigan); John Prensner (Ann Arbor, Michigan); Matthew Iyer (Ann Arbor, Michigan) |
ABSTRACT | The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to ncRNAs as diagnostic markers and clinical targets for prostate, lung, breast and pancreatic cancer. |
FILED | Wednesday, June 26, 2019 |
APPL NO | 16/453195 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390963 | Tassev |
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FUNDED BY |
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APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
INVENTOR(S) | Vladimir Tassev (Beavercreek, Ohio) |
ABSTRACT | A method of performing heteroepitaxy comprises exposing a substrate to a carrier gas, a first precursor gas, a Group II/III element, and a second precursor gas, to form a heteroepitaxial growth of one of GaAs, AlAs, InAs, GaP, InP, ZnSe, GaSe, CdSe, InSe, ZnTe, CdTe, GaTe, HgTe, GaSb, InSb, AlSb, CdS, GaN, and AlN on the substrate; wherein the substrate comprises one of GaAs, AlAs, InAs, GaP, InP, ZnSe, GaSe, CdSe, InSe, ZnTe, CdTe, GaTe, HgTe, GaSb, InSb, AlSb, CdS, GaN, and AlN; wherein the carrier gas is H2, wherein the first precursor is HCl, the Group II/III element comprises at least one of Zn, Cd, Hg, Al, Ga, and In; and wherein the second precursor is one of AsH3 (arsine), PH3 (phosphine), H2Se (hydrogen selenide), H2Te (hydrogen telluride), SbH3 (hydrogen antimonide), H2S (hydrogen sulfide), and NH3 (ammonia). The process may be an HVPE (hydride vapor phase epitaxy) process. |
FILED | Friday, December 11, 2020 |
APPL NO | 17/119131 |
ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/04 (20130101) Original (OR) Class C30B 25/18 (20130101) C30B 29/42 (20130101) C30B 29/44 (20130101) C30B 29/48 (20130101) C30B 29/406 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/3556 (20130101) G02F 1/3558 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0254 (20130101) H01L 21/0262 (20130101) H01L 21/02293 (20130101) H01L 21/02389 (20130101) H01L 21/02392 (20130101) H01L 21/02395 (20130101) H01L 21/02398 (20130101) H01L 21/02458 (20130101) H01L 21/02461 (20130101) H01L 21/02463 (20130101) H01L 21/02466 (20130101) H01L 21/02505 (20130101) H01L 21/02543 (20130101) H01L 21/02546 (20130101) H01L 21/02549 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11391158 | Senile et al. |
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FUNDED BY |
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APPLICANT(S) | General Electric Company (Schenectady, New York) |
ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
INVENTOR(S) | Darrell Glenn Senile (Oxford, Ohio); Matthew Mark Weaver (Loveland, Ohio); Alexander Martin Sener (Cincinnati, Ohio) |
ABSTRACT | Airfoil assemblies for gas turbine engines are provided. For example, an airfoil assembly comprises an airfoil, an inner band defining an inner opening shaped complementary to an inner end of the airfoil, and an outer band defining an outer opening shaped complementary to an outer end of the airfoil. The airfoil inner end is received with the inner opening, and the airfoil outer end is received within the outer opening. A strut extends radially through an airfoil cavity. A first pad is defined at a first radial location within the cavity. A second pad is defined within the cavity at a second, different radial location. In some embodiments, the airfoil assembly inner band includes a first inner flange, through which the inner band is secured to a support structure, and the outer band includes a first outer flange, through which the outer band is secured to a support structure. |
FILED | Tuesday, February 09, 2021 |
APPL NO | 17/170988 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/142 (20130101) Original (OR) Class F01D 5/147 (20130101) F01D 5/284 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/305 (20130101) F05D 2240/306 (20130101) F05D 2250/711 (20130101) F05D 2250/712 (20130101) F05D 2300/6033 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11391247 | Borissov et al. |
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APPLICANT(S) | FireFly Aerospace Inc. (Cedar Park, Texas) |
ASSIGNEE(S) | FIREFLY AEROSPACE INC. (Cedar Park, Texas) |
INVENTOR(S) | Anatoli Alimpievich Borissov (Sugar Land, Texas); Thomas Edward Markusic (Georgetown, Texas) |
ABSTRACT | A liquid rocket engine cools a thruster body by pumping propellant through cooling channels integrated in the thruster body between internal and external surfaces. One or more of the cooling channel surfaces has a variable depth along a thrust axis to mix propellant flow and destroy thermal stratification, such as a depth that varies with a repeated contiguous sinusoidal form along the thrust axis. Fuel passed through the cooling channels injects from the combustion chamber wall towards a central portion of the combustion chamber to cross impinge with oxygen injected at the combustion chamber head so that a toroidal vortex forms to enhance propellant mixing. |
FILED | Thursday, January 24, 2019 |
APPL NO | 16/256210 |
ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Jet-propulsion Plants F02K 9/52 (20130101) F02K 9/62 (20130101) F02K 9/64 (20130101) F02K 9/972 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11391550 | Hardt et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Lee R. Hardt (Ridgecrest, California); Donald L. Burnett (Spearfish, South Dakota); Josiah S. Garfield (Ridgecrest, California); Robert A. Koontz (Anchorage, Alaska); Eric K. Wooding (Ridgecrest, California); Que T. BuiDang (Ridgecrest, California) |
ABSTRACT | The disclosed embodiments are directed to enhancing insensitive munitions performance. Some of the embodiments employ an outgassing pad having unique geometrical configurations, compositions, and positioning. Other embodiments rely on using thermally-releasable components to foster billet expulsion. Additional embodiments combine both aspects into entire cook-off mitigation systems for insensitive munitions improvements. |
FILED | Thursday, May 07, 2020 |
APPL NO | 16/868734 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 17/16 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 12/20 (20130101) F42B 12/207 (20130101) Original (OR) Class F42B 39/14 (20130101) F42B 39/20 (20130101) Ammunition Fuzes; Arming or Safety Means Therefor F42C 19/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11391562 | Nguyen et al. |
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APPLICANT(S) | iSenseCloud, Inc. (San Jose, California) |
ASSIGNEE(S) | iSenseCloud, Inc. (Milpitas, California) |
INVENTOR(S) | An-Dien Nguyen (Fremont, California); An H. Nguyen (Fremont, California) |
ABSTRACT | A fiber optic voltage conditioner, and method therefor, generally relate to voltage conditioning. In such a fiber optic voltage conditioner, there is a laser, and an optical circulator is coupled to receive a light signal from the laser. A controller is coupled to the laser and is configured to generate first control information for wavelength-drift control of the laser. A data acquisition module is coupled to the controller and is configured to generate second control information for the controller for adjustment of the first control information. A photodetector is coupled to the optical circulator to receive a returned optical signal and is coupled to the data acquisition module to provide an analog output signal thereto. The photodetector is configured to generate the analog output signal responsive to the returned optical signal. The data acquisition module is configured to generate the second control information using the analog output signal. |
FILED | Thursday, February 20, 2020 |
APPL NO | 16/796447 |
ART UNIT | 2828 — Semiconductors/Memory |
CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/165 (20130101) Original (OR) Class Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/3206 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/0612 (20130101) H01S 5/0617 (20130101) H01S 5/0622 (20130101) H01S 5/0687 (20130101) H01S 5/02415 (20130101) H01S 5/4087 (20130101) H01S 5/06804 (20130101) H01S 5/06808 (20130101) H01S 5/06837 (20130101) Transmission H04B 10/572 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11391734 | Gopinath et al. |
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APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
INVENTOR(S) | Ashwin Gopinath (Pasadena, California); Paul W. K. Rothemund (Pasadena, California) |
ABSTRACT | Bistable devices are constructed using a polynucleotide platform for sensing molecular events such as binding or conformational changes of target molecules. Uses include measurement of target concentration, measuring the effect of environmental condition (such as heat, light, or pH) on the target, or screening a library for molecules that bind the target or modulate its biological function. Devices comprise three regions: a top lid, bottom lid, and flexible linker or hinge between them. A device has an open configuration in which the top and bottom lid are separated, and a closed configuration they are bound close together. Binding domains or variations of the target molecule are fixed to a device so that when the molecular event occurs, the device switches from open to closed, or vice versa, which generates a signal. Optimal device design is determined by the signal modality (optical or electronic) used to measure closure of surface-immobilized devices. |
FILED | Thursday, March 28, 2019 |
APPL NO | 16/367240 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 2310/20 (20170501) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/47 (20130101) G01N 21/553 (20130101) G01N 21/6428 (20130101) G01N 33/544 (20130101) G01N 33/54373 (20130101) Original (OR) Class G01N 2021/6439 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11391806 | Owen |
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FUNDED BY |
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APPLICANT(S) | Henry S. Owen (Medford, New Jersey) |
ASSIGNEE(S) | HENRY S. OWEN LLC (Medford, New Jersey) |
INVENTOR(S) | Henry S. Owen (Medford, New Jersey) |
ABSTRACT | Methods and systems disclosed herein may include receiving signals from a transmitter in a receiver; determine a bias of the transmitter and receiver; generating expected observations, based on the bias, corresponding to the received signals; and calculate a building height based on a power level of the received signals and a power level of the expected observations. |
FILED | Tuesday, March 03, 2020 |
APPL NO | 16/807789 |
ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 1/02 (20130101) Original (OR) Class G01S 5/021 (20130101) G01S 5/0252 (20130101) G01S 5/0294 (20130101) G01S 19/22 (20130101) G01S 19/40 (20130101) G01S 19/071 (20190801) G01S 19/072 (20190801) G01S 19/428 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11391832 | Burke |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | David Burke (Boston, Massachusetts) |
ABSTRACT | A phase Doppler radar system may comprise a pulse Doppler receiver/transmitter (R/T) subsystem coupled with a processing subsystem. The system may determine target velocity and target detection events by collecting pulses from the pulse Doppler R/T subsystem, determine an undifferentiated phase of each of the pulses, differentiate the pulses, and determine a differentiated phase of each of the pulses. The system may perform a linear fit of the differentiated phases of the pulses to produce a slope and an intercept. The system may determine a set of initial estimates of coefficients of a nonlinear fit equation. The system may perform iterations of a nonlinear least squares fit, beginning with the initial coefficient estimates, to produce a non-linear fit result. The system may determine a goodness-of-fit (GoF) statistic associated with the nonlinear fit result, and declare a detection event when the GoF is superior to a GoF statistic associated Gaussian noise. |
FILED | Wednesday, October 10, 2018 |
APPL NO | 16/156411 |
ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/292 (20130101) G01S 7/414 (20130101) G01S 13/53 (20130101) G01S 13/582 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11391866 | Barton, III et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | David Russell Barton, III (Somerville, Massachusetts); Mark Lawrence (Saint Louis, Missouri); Jennifer A. Dionne (Menlo Park, California); Jefferson Dixon (Staten Island, New York) |
ABSTRACT | High quality factor electromagnetic metasurfaces are provided. The metasurface is configured to have in plane guided-mode resonances (e.g., corresponding to waveguide modes or the like). Coupling features are included in the metasurface that are configured to couple free-space radiation to the guided mode resonances. The resulting structures have a high-Q response to free-space radiation and can be used for various applications, such as beam splitting, beam steering, and beam focusing or defocusing. |
FILED | Wednesday, November 04, 2020 |
APPL NO | 17/089384 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) G02B 1/005 (20130101) Original (OR) Class G02B 6/12 (20130101) G02B 6/26 (20130101) G02B 27/1086 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11391896 | Fard |
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FUNDED BY |
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APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
INVENTOR(S) | Erfan M. Fard (Tucson, Arizona) |
ABSTRACT | In accordance with a method for transferring optical signals to and from an optical component incorporated in a photonic integrated circuit (PIC), an incoming optical signal in a first polarization state is received at a splitter section of a polarization splitter rotator (PSR). The splitter section causes the optical signal to be directed to a first waveguide of a pair of waveguides of the PSR. One of the waveguides rotates a polarization state of an optical signal traversing therethrough into an orthogonal polarization state and the other waveguide maintains a polarization state of an optical signal traversing therethrough. The incoming optical signal is directed from the first waveguide to the optical component. An outgoing optical signal is received in a second waveguide of the pair such that the outgoing optical signal traverses the second waveguide and the splitter section to be output by the PSR. |
FILED | Thursday, May 16, 2019 |
APPL NO | 17/056578 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/4213 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11391959 | Kokubun et al. |
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FUNDED BY |
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APPLICANT(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
INVENTOR(S) | Daniel N. Kokubun (Waipahu, Hawaii); Mark Branham (Trafalgar, Indiana); Sidney Pang (Kaneohe, Hawaii); Mark Segawa (Wahiawa, Hawaii) |
ABSTRACT | Techniques are provided for laser illumination employing closely spaced laser beams. A system implementing the techniques according to an embodiment includes a semi-cylindrical optical block comprising a curved surface and a planar surface. The system further includes two laser sources configured to direct first and second laser beams to the curved surface, such that the first laser beam enters and exits the block parallel to and offset from the planar surface by a selected translation distance, and the second laser beam enters the block at a critical angle relative to the planar surface. The critical angle is associated with total internal reflection of the second laser beam along the planar surface, such that the second laser beam exits the block parallel to, and separated from, the first laser beam exiting the optical block. The separation of the exiting first and second laser beams is controlled by the selected translation distance. |
FILED | Wednesday, August 21, 2019 |
APPL NO | 16/546758 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/48 (20130101) G02B 27/108 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11392529 | Linderman et al. |
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FUNDED BY |
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APPLICANT(S) | GOVERMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (Rome, New York) |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Rome, New York) |
INVENTOR(S) | Mark H Linderman (Rome, New York); Qing Wu (Manlius, New York); Dennis Fitzgerald (Sauquoit, New York) |
ABSTRACT | An apparatus for a microprocessor computer system and method for configuring the same where said microprocessor computer system comprises a processor core and at least one hardware buffer FIFO with memory-mapped head and tail that handles data movement among the processor cores, networks, raw data input and outputs, and memory. The method for configuring said microprocessor computer system comprises utilizing a FIFO auxiliary processor to process said data traversing said hardware FIFO; utilizing said hardware FIFOs to efficiently pipe data through functional blocks; and utilizing a FIFO controller to perform DMA operations that include non-unit-stride access patterns and transfers among processor cores, networks, raw data input and outputs, memory, and other memory-mapped hardware FIFOs. |
FILED | Tuesday, May 28, 2019 |
APPL NO | 16/423282 |
ART UNIT | 2181 — Computer Architecture and I/O |
CURRENT CPC | Electric Digital Data Processing G06F 13/404 (20130101) Original (OR) Class G06F 13/4022 (20130101) G06F 13/4031 (20130101) G06F 13/4081 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11392699 | Rubin |
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FUNDED BY |
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APPLICANT(S) | SPAWAR Systems Center Pacific (San Diego, California) |
ASSIGNEE(S) | United States of America as Represented by Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Stuart H. Rubin (San Diego, California) |
ABSTRACT | A device, method, and system for synthesizing variants of semantically equivalent computer source code using computer source code components to protect against cyberattacks. An input constraint, an output constraint, and a schema are received from a user. A component-based synthesizer generates first computer source code including a first computer source code component based on the input constraint, the output constraint, and the schema. The component-based synthesizer generates second computer source code including a second computer source code component based on the input constraint, the output constraint, and the schema. The second computer source code is generated as a semantically equivalent variant of the first computer source code to provide for protection against a cyberattack. The invention may also include a dynamic component library. |
FILED | Wednesday, March 20, 2019 |
APPL NO | 16/359821 |
ART UNIT | 2191 — Interprocess Communication and Software Development |
CURRENT CPC | Electric Digital Data Processing G06F 8/36 (20130101) G06F 8/70 (20130101) G06F 21/57 (20130101) Original (OR) Class G06F 2221/033 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11392827 | Rubin |
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FUNDED BY |
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APPLICANT(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (San Diego, California) |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Stuart H. Rubin (San Diego, California) |
ABSTRACT | A method includes providing a set of deep learning neural networks where no pair of deep learning neural networks within the set of deep learning neural networks produces a semantically equivalent output by design. An input to the set of deep learning neural networks is provided, where responsive to the input, one or more of the deep learning neural networks produces an output. The output of the deep learning neural networks is input into a case-based reasoning (CBR) system. The CBR system generates an output responsive to the input received by the CBR system if the input received by the CBR system is known by the CBR system. The output of the CBR system is then determined to be a correct/incorrect output. One of the deep learning neural networks is trained on the correct output if the correct output is specific to the particular deep learning neural network. |
FILED | Tuesday, July 17, 2018 |
APPL NO | 16/037683 |
ART UNIT | 2486 — Recording and Compression |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class G06N 3/0454 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11393353 | Del Sesto et al. |
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FUNDED BY |
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APPLICANT(S) | UI LABS (Chicago, Illinois) |
ASSIGNEE(S) | UI LABS (Chicago, Illinois) |
INVENTOR(S) | Antonio Del Sesto (Chicago, Illinois); Rodrigo Santos Quintella Freire (Chicago, Illinois); Alejandro Velez (Park Ridge, Illinois) |
ABSTRACT | An industrial operations network is disclosed herein. More particularly the disclosure may pertain to an industrial operations network designed for facilitating the training of security concepts for industrial operations. In one embodiment, an apparatus for training industrial security concepts is disclosed. The apparatus may comprise a portable industrial operations network comprising: at least one router; at least one firewall; at least one programmable logic controller; and at least one display connected to the portable industrial operations network, said at least one display adapted to display, at different times, normal operating conditions of said portable industrial operations network and security fault conditions in said portable industrial operations network. |
FILED | Wednesday, September 30, 2020 |
APPL NO | 17/039540 |
ART UNIT | 3715 — Amusement and Education Devices |
CURRENT CPC | Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 5/06 (20130101) Original (OR) Class G09B 9/00 (20130101) G09B 19/0053 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11393355 | Warren et al. |
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FUNDED BY |
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APPLICANT(S) | BETA AIR, LLC (South Burlington, Vermont) |
ASSIGNEE(S) | BETA AIR, LLC (South Burlington, Vermont) |
INVENTOR(S) | Nicholas Granger Warren (Burlington, Vermont); Charles C. Guthrie (Burlington, Vermont); Nicholas Moy (Burlington, Vermont); Alexander Hoekje List (South Burlington, Vermont) |
ABSTRACT | A system for flight simulation of an electric aircraft. The system includes a pilot control. The pilot control is configured to receive an input from a user. The system includes a pilot command that is generated by the pilot control. The system includes a computing device configured to generate a simulation. The simulation includes an electric aircraft model. The electric aircraft model is configured to simulate a performance of an electric aircraft. The performance is determined by at least the pilot command. The simulation is configured to provide feedback to the user based on the performance of the electric aircraft. The simulation is further configured to updated the electric aircraft model as a function of the pilot command. |
FILED | Tuesday, July 13, 2021 |
APPL NO | 17/373889 |
ART UNIT | 3715 — Amusement and Education Devices |
CURRENT CPC | Electric Digital Data Processing G06F 30/20 (20200101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 9/24 (20130101) G09B 9/085 (20130101) Original (OR) Class G09B 9/165 (20130101) G09B 9/301 (20130101) G09B 9/307 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11393558 | Bo et al. |
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FUNDED BY |
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APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
INVENTOR(S) | Chunkun Bo (Charlottesville, Virginia); Kevin Skadron (Charlottesville, Virginia); Elaheh Sadredini (Charlottesville, Virginia); Vinh Dang (Charlottesville, Virginia) |
ABSTRACT | A method of operating a finite state machine circuit can be provided by determining if a target sequence of characters included in a string of reference characters occurs within a specified difference distance using states indicated by the finite state machine circuit to indicate a number of character mis-matches between the target sequence of characters and a respective sequence of characters within the string of reference characters. |
FILED | Friday, February 16, 2018 |
APPL NO | 15/932287 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Electric Digital Data Processing G06F 16/90344 (20190101) Computer Systems Based on Specific Computational Models G06N 5/047 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 30/00 (20190201) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11393970 | Majkic et al. |
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FUNDED BY |
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APPLICANT(S) | University of Houston System (Houston, Texas) |
ASSIGNEE(S) | University of Houston System (Houston, Texas) |
INVENTOR(S) | Goran Majkic (Houston, Texas); Venkat Selvamanickam (Houston, Texas) |
ABSTRACT | A superconductor tape and method for manufacturing, measuring, monitoring, and controlling same are disclosed. Embodiments are directed to a superconductor tape which includes a superconductor film overlying a buffer layer which overlies a substrate. In one embodiment, the superconductor film is defined as having a c-axis lattice constant higher than 11.74 Angstroms. In another embodiment, the superconductor film comprises BaMO3, where M=Zr, Sn, Ta, Nb, Hf, or Ce, and which has a (101) peak of BaMO3 elongated along an axis that is between 60° to 90° from an axis of the (001) peaks of the superconductor film. These and other embodiments achieve well-aligned nanocolumnar defects and thus a high lift factor, which can result in superior critical current performance of the tape in, for example, high magnetic fields. |
FILED | Tuesday, August 29, 2017 |
APPL NO | 16/329658 |
ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/126 (20130101) H01L 39/143 (20130101) H01L 39/2441 (20130101) H01L 39/2461 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 40/60 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11393976 | Jarillo-Herrero et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
INVENTOR(S) | Pablo Jarillo-Herrero (Cambridge, Massachusetts); Qiong Ma (Cambridge, Massachusetts); Nuh Gedik (Watertown, Massachusetts); Suyang Xu (Cambridge, Massachusetts); Zhiren Zheng (Cambridge, Massachusetts) |
ABSTRACT | An ultrathin, carbon-based memristor with a moiré superlattice potential shows prominent ferroelectric resistance switching. The memristor includes a bilayer material, such as Bernal-stacked bilayer graphene, encapsulated between two layers of a layered material, such as hexagonal boron nitride. At least one of the encapsulating layers is rotationally aligned with the bilayer to create the moiré superlattice potential. The memristor exhibits ultrafast and robust resistance switching between multiple resistance states at high temperatures. The memristor, which may be volatile or nonvolatile, may be suitable for neuromorphic computing. |
FILED | Tuesday, November 10, 2020 |
APPL NO | 17/094141 |
ART UNIT | 2827 — Semiconductors/Memory |
CURRENT CPC | Static Stores G11C 13/0069 (20130101) G11C 2213/35 (20130101) G11C 2213/53 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 45/10 (20130101) Original (OR) Class H01L 45/142 (20130101) H01L 45/143 (20130101) H01L 45/148 (20130101) H01L 45/149 (20130101) H01L 45/1206 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11394017 | Eskra et al. |
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FUNDED BY |
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APPLICANT(S) | Eskra Technical Products, Inc. (Saukville, Wisconsin) |
ASSIGNEE(S) | Eskra Technical Products, Inc. (Saukville, Wisconsin) |
INVENTOR(S) | Michael David Eskra (Saukville, Wisconsin); Paula Margaret Ralston (Frederick, Maryland); Rodney Mortensen LaFollette (South Jordan, Utah); James Bernard Nowakowski (Washburn, Wisconsin) |
ABSTRACT | A solventless system for fabricating electrodes includes a mechanism for feeding a substrate through the system, a first application region comprised of a first device for applying a first layer to the substrate, wherein the first layer is comprised of an active material mixture and a binder, and the binder includes at least one of a thermoplastic material and a thermoset material, and the system includes a first heater positioned to heat the first layer. |
FILED | Monday, May 17, 2021 |
APPL NO | 17/302944 |
ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/0404 (20130101) Original (OR) Class H01M 4/0419 (20130101) H01M 4/622 (20130101) H01M 4/623 (20130101) H01M 4/625 (20130101) H01M 4/1391 (20130101) H01M 4/1393 (20130101) H01M 4/1395 (20130101) H01M 10/0565 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11394062 | Sloop |
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FUNDED BY |
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APPLICANT(S) | Hulico LLC (Bend, Oregon) |
ASSIGNEE(S) | HULICO LLC (Bend, Oregon) |
INVENTOR(S) | Steven E. Sloop (Bend, Oregon) |
ABSTRACT | Examples are disclosed of methods to recycle positive-electrode material of a lithium-ion battery. One example provides a method including relithiating the positive-electrode material in a solution comprising lithium ions and an oxidizing agent, and after relithiating, separating the positive-electrode material from the solution. |
FILED | Friday, May 17, 2019 |
APPL NO | 16/415879 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/54 (20130101) Original (OR) Class H01M 10/0525 (20130101) H01M 2004/028 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11394085 | Eskra et al. |
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FUNDED BY |
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APPLICANT(S) | Eskra Technical Products, Inc. (Saukville, Wisconsin) |
ASSIGNEE(S) | Eskra Technical Products, Inc. (Saukville, Wisconsin) |
INVENTOR(S) | Michael David Eskra (Saukville, Wisconsin); Paula Margaret Ralston (Frederick, Maryland) |
ABSTRACT | A system and method for providing a ceramic-based separator onto an electrode is disclosed. A separator is formed on the electrode via a dry, solvent-free application of a ceramic-based separator to the electrode. An electrode is provided to an application area via a feed mechanism and a separator layer is then applied to the electrode that is comprised of a binder including at least one of a thermoplastic material and a thermoset material and an electrically non-conductive separator material, with the separator layer being applied to the electrode via a dry dispersion application. |
FILED | Monday, June 28, 2021 |
APPL NO | 17/304862 |
ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/052 (20130101) H01M 50/46 (20210101) Original (OR) Class H01M 50/403 (20210101) H01M 50/446 (20210101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11394111 | Khushrushahi |
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FUNDED BY |
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APPLICANT(S) | Notch, Inc. (Cambridge, Massachusetts) |
ASSIGNEE(S) | Notch, Inc. (Cambridge, Massachusetts) |
INVENTOR(S) | Shahriar Khushrushahi (Cambridge, Massachusetts) |
ABSTRACT | A reconfigurable antenna systems includes a set of envelopes of active metamaterial panels, each envelope in the set being shaped to approximate a surface of at least partial revolution of a curve about an axis, wherein the surface defines a focal locus; a wideband antenna array disposed within the focal locus; and a controller, coupled to the panels, configured to activate each one of the panels, so as to control a property of each of the panels, the property selected from the group consisting of transmissivity, reflectivity, absorption, phase, polarization, bandwidth, angle sensitivity, resonant frequency, and combinations thereof. |
FILED | Friday, August 14, 2020 |
APPL NO | 16/993732 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/425 (20130101) Original (OR) Class H01Q 15/147 (20130101) H01Q 15/148 (20130101) H01Q 19/17 (20130101) H01Q 19/18 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11394126 | White et al. |
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FUNDED BY |
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APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
ASSIGNEE(S) | HRL LABORATORIES, LLC (Malibu, California) |
INVENTOR(S) | Carson R. White (Agoura Hills, California); Hyok J. Song (Oak Park, California); Christopher P. Henry (Thousand Oaks, California) |
ABSTRACT | A distributed transmitter antenna includes a plurality of antenna segments and a plurality of transmitters. A first transmitter of the plurality of transmitters is coupled to a first antenna segment of the plurality of antenna segments, and a second transmitter of the plurality of transmitters is coupled to the first antenna segment and a second antenna segment of the plurality of antenna segments. |
FILED | Friday, July 24, 2020 |
APPL NO | 16/938369 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 9/16 (20130101) H01Q 9/30 (20130101) H01Q 21/12 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11394471 | Govoni et al. |
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FUNDED BY |
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APPLICANT(S) | U.S. Army Combat Capabilities Development Command, Army Research Laboratory (Adelphi, Maryland) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Mark A. Govoni (Abingdon, Maryland); John T. Clark (Elkridge, Maryland) |
ABSTRACT | A method and apparatus for detecting RF power comprising an input port configured to receive a high-power RF signal, at least one diamond chip attenuator, coupled to the input port, configured to attenuate the high-power RF signal, and an RF detector integrated circuit, coupled to the at least one diamond chip attenuator, configured to convert the attenuated RF signal into an output indicium representing a power level of the high-powered RF signal. |
FILED | Wednesday, March 24, 2021 |
APPL NO | 17/210552 |
ART UNIT | 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 21/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/66 (20130101) H01L 29/1602 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 7/25 (20130101) Transmission H04B 17/101 (20150115) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 11389069 | Grudic et al. |
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FUNDED BY |
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APPLICANT(S) | Flashback Technologies, Inc. (Boulder, Colorado); The Regents of the University of Colorado (Denver, Colorado) |
ASSIGNEE(S) | Flashback Technologies, Inc. (Westfield, New Jersey); The Regents of the University of Colorado (Denver, Colorado) |
INVENTOR(S) | Gregory Zlatko Grudic (Niwot, Colorado); Steven L. Moulton (Littleton, Colorado); Isobel Jane Mulligan (Niwot, Colorado) |
ABSTRACT | Tools and techniques for estimating a probability that a patient is bleeding or has sustained intravascular volume loss (e.g., due to hemodialysis or dehydration) and/or to estimate a patient's current hemodynamic reserve index, track the patient's hemodynamic reserve index over time, and/or predict a patient's hemodynamic reserve index in the future. Tools and techniques for estimating and/or predicting a patient's dehydration state. Tools and techniques for controlling a hemodialysis machine based on the patient's estimated and/or predicted hemodynamic reserve index. |
FILED | Thursday, July 13, 2017 |
APPL NO | 15/649411 |
ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/021 (20130101) A61B 5/029 (20130101) A61B 5/318 (20210101) A61B 5/02028 (20130101) Original (OR) Class A61B 5/02042 (20130101) A61B 5/7275 (20130101) A61B 5/14551 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/60 (20180101) G16H 50/30 (20180101) Technologies for Adaptation to Climate Change Y02A 90/10 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389083 | Bansbach et al. |
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FUNDED BY |
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APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Heather Bansbach (Chesterfield, Virginia); Timothy Crawford Sell (Pittsburgh, Pennsylvania) |
ABSTRACT | A neuromuscular, physiological, biomechanical, or musculoskeletal activity monitoring system for a subject is provided. The system includes a wearable inertial measurement unit including at least one accelerometer and/or at least one gyroscope. The system also includes a controller in communication with an output component. The controller is configured to: receive and process information from the inertial measurement unit representative of one or more physical actions performed by the subject; generate an inertial data set for the one or more physical actions based on the received and processed information; compare the generated inertial data set to reference data stored on computer readable memory in communication with the controller; and cause the output component to provide feedback including predictive injury information. The predictive injury information is based, at least in part, on the comparison between the generated data set and the reference data. |
FILED | Thursday, October 06, 2016 |
APPL NO | 15/766165 |
ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/22 (20130101) A61B 5/45 (20130101) A61B 5/486 (20130101) A61B 5/743 (20130101) A61B 5/744 (20130101) A61B 5/1118 (20130101) Original (OR) Class A61B 5/1121 (20130101) A61B 5/6801 (20130101) A61B 5/7435 (20130101) A61B 2503/10 (20130101) A61B 2505/09 (20130101) A61B 2560/0223 (20130101) A61B 2560/0462 (20130101) A61B 2562/028 (20130101) A61B 2562/0219 (20130101) A61B 2562/0247 (20130101) Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 2220/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389395 | Wrenn et al. |
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APPLICANT(S) | DREXEL UNIVERSITY (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
INVENTOR(S) | Steven P. Wrenn (Swarthmore, Pennsylvania); Stephen Dicker (Philadelphia, Pennsylvania) |
ABSTRACT | The present invention includes a construct that comprises at least one microbubble encapsulated within the aqueous core of a microcapsule. The present invention also includes a pharmaceutical composition comprising a construct comprising at least one microbubble encapsulated within the aqueous core of a microcapsule. The present invention further includes a method of imaging a tissue or organ in a subject, a method of delivering a therapeutic cargo to a tissue or organ in a subject, and a method of treating a disease or disorder in a subject. |
FILED | Friday, May 29, 2020 |
APPL NO | 16/887974 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0009 (20130101) Original (OR) Class A61K 9/1271 (20130101) A61K 9/5031 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389788 | Katz et al. |
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APPLICANT(S) | Chevron U.S.A. Inc. (San Ramon, California); The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | Chevron U.S.A. Inc. (San Ramon, California); The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Alexander Katz (Richmond, California); Alexander Okrut (Oakland, California); Martina Aigner (Berkeley, California); Xiaoying Ouyang (El Cerrito, California); Stacey Ian Zones (San Francisco, California) |
ABSTRACT | Provided is a scalable delamination of a SSZ-70 framework zeolite, without the need for sonication, which has been previously made difficult by the charged nature of the imidazolium structure-directing agents that are required for zeolite synthesis. The method comprises contacting a B-SSZ-70 zeolite precursor with a zinc source such as zinc nitrate and a fluoride source. |
FILED | Thursday, February 14, 2019 |
APPL NO | 16/275945 |
ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 29/86 (20130101) Original (OR) Class B01J 29/89 (20130101) B01J 2229/22 (20130101) B01J 2229/34 (20130101) Non-metallic Elements; Compounds Thereof; C01B 39/04 (20130101) C01B 39/026 (20130101) C01B 39/48 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/86 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389800 | Sperling et al. |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Ralph Alexander Sperling (Eltville, Germany); Adam R. Abate (San Francisco, California); David A. Weitz (Bolton, Massachusetts) |
ABSTRACT | The present invention generally relates to systems and techniques for manipulating fluids and/or making droplets. In certain aspects, the present invention generally relates to droplet production. The droplets may be formed from fluids from different sources. In one set of embodiments, the present invention is directed to a microfluidic device comprising a plurality of droplet-making units, and/or other fluidic units, which may be substantially identical in some cases. Substantially each of the fluidic units may be in fluidic communication with a different source of a first fluid and a common source of a second fluid, in certain embodiments. In one aspect, substantially the same pressure may be applied to substantially all of the different sources of fluid, which may be used to cause fluid to move from the different sources into the microfluidic device. In some cases, the fluids may interact within the fluidic units, e.g., by reacting, or for the production of droplets within the microfluidic device. In some cases, the droplets may be used, for example, to form a library of droplets. |
FILED | Thursday, September 27, 2012 |
APPL NO | 14/348113 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 23/41 (20220101) B01F 33/3011 (20220101) B01F 33/3021 (20220101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/0268 (20130101) B01L 3/502784 (20130101) Original (OR) Class B01L 2200/0673 (20130101) B01L 2300/0816 (20130101) B01L 2300/0867 (20130101) B01L 2300/0883 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/212 (20150401) Y10T 137/0391 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389834 | Horowitz et al. |
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APPLICANT(S) | AMP Robotics Corporation (Louisville, Colorado) |
ASSIGNEE(S) | AMP Robotics Corporation (Louisville, Colorado) |
INVENTOR(S) | Matanya B. Horowitz (Golden, Colorado); James A. Bailey (Boulder, Colorado); John C. McCoy, Jr. (Thornton, Colorado) |
ABSTRACT | Systems and methods for sorting recyclable items and other materials are provided. In one embodiment, a system for sorting objects comprises: at least one imaging sensor; a controller comprising a processor and memory storage, wherein the controller receives image data captured by the image sensor; and at least one pusher device coupled to the controller, wherein the at least one pusher device is configured to receive an actuation signal from the controller. The processor is configured to detect objects travelling on a conveyor device and recognize at least one target item traveling on a conveyor device by processing the image data and to determine an expected time when the at least one target item will be located within a diversion path of the pusher device. The controller selectively generates the actuation signal based on whether a sensed object detected in the image data comprise the at least one target item. |
FILED | Friday, October 02, 2020 |
APPL NO | 17/062383 |
ART UNIT | 3653 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 1/04 (20130101) B07C 5/36 (20130101) B07C 5/367 (20130101) B07C 5/368 (20130101) B07C 5/3422 (20130101) Original (OR) Class B07C 2501/0054 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/027 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389866 | Rosi et al. |
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APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Nathaniel L. Rosi (Pittsburgh, Pennsylvania); Andrea David Merg (Pittsburgh, Pennsylvania); Soumitra Punekar (Pittsburgh, Pennsylvania) |
ABSTRACT | Described herein are metal nanoparticle superstructures and methods and compounds for making the same. |
FILED | Thursday, December 14, 2017 |
APPL NO | 15/842625 |
ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/07 (20220101) Original (OR) Class B22F 1/054 (20220101) B22F 1/0553 (20220101) B22F 9/24 (20130101) B22F 2301/255 (20130101) Nanostructures Formed by Manipulation of Individual Atoms, Molecules, or Limited Collections of Atoms or Molecules as Discrete Units; Manufacture or Treatment Thereof B82B 3/0009 (20130101) B82B 3/0066 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 40/00 (20130101) Heterocyclic Compounds C07D 249/04 (20130101) Peptides C07K 7/08 (20130101) C07K 17/14 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11389902 | Vadali et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Venkata Madhukanth Vadali (Madison, Wisconsin); Chao Ma (Madison, Wisconsin); Neil Arthur Duffie (Madison, Wisconsin); Xiaochun Li (Madison, Wisconsin); Frank Ewald Pfefferkorn (Madison, Wisconsin) |
ABSTRACT | Surface asperities, such as roughness characteristics, are reduced or otherwise mitigated via the control of surface regions including the asperities in different regimes. In accordance with various embodiments, the height of both high-frequency and low-frequency surface asperities is reduced by controlling characteristics of a surface region under a first regime to flow material from the surface asperities. A second regime is implemented to reduce a height of high-frequency surface asperities in the surface region by controlling characteristics of the surface region under a second regime to flow material that is predominantly from the high-frequency surface asperities, the controlled characteristics in the second regime being different than the controlled characteristics in the first regime. Such aspects may include, for example, controlling melt pools in each regime via energy pulses, to respectively mitigate/reduce the asperities. |
FILED | Monday, June 10, 2019 |
APPL NO | 16/436228 |
ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/354 (20151001) Original (OR) Class B23K 26/3576 (20180801) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390835 | Sawyer et al. |
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FUNDED BY |
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APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
INVENTOR(S) | Wallace Gregory Sawyer (Gainesville, Florida); Thomas Ettor Angelini (Gainesville, Florida); Steven Craig Ghivizzani (Gainesville, Florida); Tapomoy Bhattacharjee (Gainesville, Florida); Glyn Daniel Palmer (Gainesville, Florida) |
ABSTRACT | A three-dimensional cell growth medium is described. The cell growth medium may comprise hydrogel particles swollen with a liquid cell growth medium to form a granular gel yield stress material which undergoes a phase transformation from a solid phase to a liquid-like phase when an applied stress exceeds the yield stress. Cells may be placed in the three-dimensional cell growth medium according to any shape or geometry, and may remain in place within the three-dimensional cell growth medium. |
FILED | Saturday, May 07, 2016 |
APPL NO | 15/571866 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) Original (OR) Class C12M 25/14 (20130101) C12M 25/16 (20130101) C12M 35/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) C12N 2513/00 (20130101) C12N 2527/00 (20130101) C12N 2533/30 (20130101) C12N 2535/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390846 | Ashton et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Randolph Scott Ashton (Madison, Wisconsin); Carlos Ruben Marti-Figueroa (Madison, Wisconsin) |
ABSTRACT | Described herein are methods, compositions, and kits for forming engineered in vitro biomimetic, three-dimensional, tubular organoid structures by directed differentiation of human pluripotent stem cells within tubular channels formed in a hydrogel. |
FILED | Wednesday, October 16, 2019 |
APPL NO | 16/654952 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) C12N 5/0618 (20130101) Original (OR) Class C12N 2500/05 (20130101) C12N 2500/32 (20130101) C12N 2500/38 (20130101) C12N 2501/33 (20130101) C12N 2501/999 (20130101) C12N 2506/02 (20130101) C12N 2506/03 (20130101) C12N 2506/45 (20130101) C12N 2513/00 (20130101) C12N 2533/18 (20130101) C12N 2533/30 (20130101) C12N 2533/74 (20130101) C12N 2537/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11391563 | Luo et al. |
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FUNDED BY |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Qiaoen Luo (West Lafayette, Indiana); Justin A. Patel (West Lafayette, Indiana); Kevin J. Webb (West Lafayette, Indiana) |
ABSTRACT | An ultra-sensitive speckle-analyzing system is disclosed which includes an image capture device configured to receive a scattered field having a speckle configuration and thereby capture i) a reference speckle image, and ii) a subsequent speckle image, each of the reference and the subsequent speckle images having a plurality of speckles on a background; and a processor configured to generate a cross-correlation between the plurality of speckles of the reference and the subsequent speckle images, to thereby represent a change in the speckle configuration. |
FILED | Friday, January 15, 2021 |
APPL NO | 17/150880 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/2441 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11391729 | Bergo |
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FUNDED BY |
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APPLICANT(S) | Adeptrix Corp. (Beverly, Massachusetts) |
ASSIGNEE(S) | ADEPTRIX CORP. (Beverly, Massachusetts) |
INVENTOR(S) | Vladislav B. Bergo (Boston, Massachusetts) |
ABSTRACT | Bead arrays suitable for analysis by mass spectrometry are disclosed. In an embodiment, a bead array includes multiple reactive sites, each of the reactive sites being capable of binding multiple distinct target analytes. |
FILED | Friday, September 07, 2018 |
APPL NO | 16/125164 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/745 (20130101) G01N 33/6845 (20130101) G01N 33/6848 (20130101) G01N 33/6854 (20130101) G01N 33/54306 (20130101) Original (OR) Class G01N 33/54313 (20130101) G01N 2440/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11391734 | Gopinath et al. |
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APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
INVENTOR(S) | Ashwin Gopinath (Pasadena, California); Paul W. K. Rothemund (Pasadena, California) |
ABSTRACT | Bistable devices are constructed using a polynucleotide platform for sensing molecular events such as binding or conformational changes of target molecules. Uses include measurement of target concentration, measuring the effect of environmental condition (such as heat, light, or pH) on the target, or screening a library for molecules that bind the target or modulate its biological function. Devices comprise three regions: a top lid, bottom lid, and flexible linker or hinge between them. A device has an open configuration in which the top and bottom lid are separated, and a closed configuration they are bound close together. Binding domains or variations of the target molecule are fixed to a device so that when the molecular event occurs, the device switches from open to closed, or vice versa, which generates a signal. Optimal device design is determined by the signal modality (optical or electronic) used to measure closure of surface-immobilized devices. |
FILED | Thursday, March 28, 2019 |
APPL NO | 16/367240 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 2310/20 (20170501) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/47 (20130101) G01N 21/553 (20130101) G01N 21/6428 (20130101) G01N 33/544 (20130101) G01N 33/54373 (20130101) Original (OR) Class G01N 2021/6439 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11391768 | Rosenzweig et al. |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | James Rosenzweig (Los Angeles, California); Nathan Majernik (Los Angeles, California) |
ABSTRACT | An apparatus and method for in-situ determination of arc location within a radio-frequency (RF) waveguide. At least one pair of sound vibration transducers are coupled to positions within the waveguide from which data is collected. When a threshold level of voltage standing wave ratio (VSWR) is exceeded, then transducer data is processed to determine time-of-flight (TOF), to then compare data between transducers, to identify the faster longitudinal component with speed of sound in the material of the waveguide, from which longitudinal position information about the arc is generated. |
FILED | Tuesday, July 23, 2019 |
APPL NO | 16/520303 |
ART UNIT | 2863 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/1209 (20130101) Original (OR) Class G01R 31/1272 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11391866 | Barton, III et al. |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | David Russell Barton, III (Somerville, Massachusetts); Mark Lawrence (Saint Louis, Missouri); Jennifer A. Dionne (Menlo Park, California); Jefferson Dixon (Staten Island, New York) |
ABSTRACT | High quality factor electromagnetic metasurfaces are provided. The metasurface is configured to have in plane guided-mode resonances (e.g., corresponding to waveguide modes or the like). Coupling features are included in the metasurface that are configured to couple free-space radiation to the guided mode resonances. The resulting structures have a high-Q response to free-space radiation and can be used for various applications, such as beam splitting, beam steering, and beam focusing or defocusing. |
FILED | Wednesday, November 04, 2020 |
APPL NO | 17/089384 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) G02B 1/005 (20130101) Original (OR) Class G02B 6/12 (20130101) G02B 6/26 (20130101) G02B 27/1086 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11392031 | Stowers et al. |
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APPLICANT(S) | Inpria Corporation (Corvallis, Oregon) |
ASSIGNEE(S) | Inpria Corporation (Corvallis, Oregon) |
INVENTOR(S) | Jason K. Stowers (Corvallis, Oregon); Alan J. Telecky (Albany, Oregon); Douglas A. Keszler (Corvallis, Oregon); Andrew Grenville (Corvallis, Oregon) |
ABSTRACT | Stabilized precursor solutions can be used to form radiation inorganic coating materials. The precursor solutions generally comprise metal suboxide cations, peroxide-based ligands and polyatomic anions. Design of the precursor solutions can be performed to achieve a high level of stability of the precursor solutions. The resulting coating materials can be designed for patterning with a selected radiation, such as ultraviolet light, x-ray radiation or electron beam radiation. The radiation patterned coating material can have a high contrast with respect to material properties, such that development of a latent image can be successful to form lines with very low line-width roughness and adjacent structures with a very small pitch. |
FILED | Thursday, May 28, 2020 |
APPL NO | 16/885581 |
ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/20 (20130101) G03F 7/0042 (20130101) G03F 7/0043 (20130101) Original (OR) Class G03F 7/327 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24355 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11392644 | Idreos et al. |
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APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
INVENTOR(S) | Stratos Idreos (Cambridge, Massachusetts); Niv Dayan (Somerville, Massachusetts); Manoussos Gavriil Athanassoulis (Cambridge, Massachusetts) |
ABSTRACT | Embodiments of the invention utilize an improved LSM-tree-based key-value approach to strike the optimal balance between the costs of updates and lookups with any given main memory budget. The improved approach involves allocating memory to Bloom filters differently across different levels so as to minimize the sum of the false positive rates associated with the Bloom filters. In addition, the improved approach may predict the impact of the system design parameter(s) and/or environmental parameter(s) on the lookup performance. Subsequently, the improved approach may “self-tune” the system design parameter(s) and/or environment parameter(s) to maximize the throughput. |
FILED | Tuesday, January 09, 2018 |
APPL NO | 16/433075 |
ART UNIT | 2162 — Data Bases & File Management |
CURRENT CPC | Electric Digital Data Processing G06F 3/067 (20130101) G06F 16/2246 (20190101) G06F 16/9014 (20190101) Original (OR) Class G06F 16/9535 (20190101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11392831 | Sarioglu et al. |
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APPLICANT(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Ali Fatih Sarioglu (Atlanta, Georgia); Ningquan Wang (Atlanta, Georgia) |
ABSTRACT | Systems and methods for decoding code-multiplexed Coulter signals are described herein. An example method can include receiving a code-multiplexed signal detected by a network of Coulter sensors, where the code-multiplexed signal includes a plurality of distinct Coulter signals, and inputting the code-multiplexed signal into a deep-learning network. The method can also include determining information indicative of at least one of a size, a speed, or a location of a particle detected by the network of Coulter sensors by using the deep-learning network to process the code-multiplexed signal. The method can further include storing the information indicative of at least one of the size, the speed, or the location of the particle detected by the network of Coulter sensors. |
FILED | Thursday, October 17, 2019 |
APPL NO | 17/285561 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/12 (20130101) G01N 15/1056 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6257 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class G06N 3/0472 (20130101) G06N 3/0481 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11393973 | Ghatge et al. |
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APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
INVENTOR(S) | Mayur Ghatge (Gainesville, Florida); Glen H. Walters (Gainesville, Florida); Toshikazu Nishida (Gainesville, Florida); Roozbeh Tabrizian (Gainesville, Florida) |
ABSTRACT | A nano-mechanical acoustical resonator is designed and fabricated with CMOS compatible techniques to apply to mm-wave RF front-ends and 5G wireless communication systems which have extreme small scale and integrated in 3D sensors and actuators. |
FILED | Friday, November 22, 2019 |
APPL NO | 16/692009 |
ART UNIT | 2812 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/20 (20130101) H01L 41/29 (20130101) H01L 41/053 (20130101) H01L 41/081 (20130101) H01L 41/187 (20130101) Original (OR) Class H01L 41/316 (20130101) H01L 41/0477 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 3/02 (20130101) H03H 9/13 (20130101) H03H 9/02031 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11394033 | Yang et al. |
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APPLICANT(S) | Cornell University (Ithaca, New York); Wuhan University (Wuhan, China PRC) |
ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York); WUHAN UNIVERSITY (Wuhan, China PRC) |
INVENTOR(S) | Yao Yang (Ithaca, New York); Héctor D. Abruña (Ithaca, New York); Lin Zhuang (Wuhan, China PRC); Hanging Peng (Wuhan, China PRC); Li Xiao (Wuhan, China PRC) |
ABSTRACT | Provided is an apparatus containing, as a cathode catalyst, a metal oxide/carbon catalyst composition. The metal oxide/carbon catalyst composition includes 40 to 95 wt % porous Mn—Co spinel oxide nanoparticles of the formula MnxCo3-xO4. The nanoparticles have an octahedral morphology, an average particle size of 5-100 nm, and average pore sizes of 1-5 nm (where x is the atomic fraction of manganese and 3-x is the atomic fraction of cobalt). The metal oxide nanoparticles are supported on a carbon substrate that contains at least 96 atomic % carbon. |
FILED | Monday, March 16, 2020 |
APPL NO | 16/819349 |
ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/9033 (20130101) Original (OR) Class H01M 4/9083 (20130101) H01M 8/1004 (20130101) H01M 8/1007 (20160201) H01M 8/1009 (20130101) H01M 8/1011 (20130101) H01M 2004/8689 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11394062 | Sloop |
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FUNDED BY |
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APPLICANT(S) | Hulico LLC (Bend, Oregon) |
ASSIGNEE(S) | HULICO LLC (Bend, Oregon) |
INVENTOR(S) | Steven E. Sloop (Bend, Oregon) |
ABSTRACT | Examples are disclosed of methods to recycle positive-electrode material of a lithium-ion battery. One example provides a method including relithiating the positive-electrode material in a solution comprising lithium ions and an oxidizing agent, and after relithiating, separating the positive-electrode material from the solution. |
FILED | Friday, May 17, 2019 |
APPL NO | 16/415879 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/54 (20130101) Original (OR) Class H01M 10/0525 (20130101) H01M 2004/028 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11394125 | Sur et al. |
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FUNDED BY |
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APPLICANT(S) | University of South Carolina (Columbia, South Carolina) |
ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
INVENTOR(S) | Sanjib Sur (Cayce, South Carolina); Guoan Wang (Irmo, South Carolina); Srihari Nelakuditi (Columbia, South Carolina) |
ABSTRACT | A reconfigurable antenna apparatus may include an antenna assembly and control circuitry. The antenna assembly may include an antenna patch array having a plurality of antenna patches and a switch array having plurality of switches. Each switch of the plurality switches may be electronically controllable to transition between states including a conducting state and a non-conducting state. Each switch may be electrically connected between two of the antenna patches of the antenna array. The control circuitry may be configured to control the states of the switches of the switch array to operate the antenna patch array in a first communications mode at a first wavelength, and control the states of the switches of the switch array to operate the antenna patch array in a second communications mode at a second wavelength. |
FILED | Friday, August 21, 2020 |
APPL NO | 16/999391 |
ART UNIT | 2844 — Electrical Circuits and Systems |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/38 (20130101) H01Q 1/243 (20130101) H01Q 9/0407 (20130101) H01Q 21/065 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11394377 | Carrigan |
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FUNDED BY |
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APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Joseph T. Carrigan (Columbia, Maryland) |
ABSTRACT | An embodiment in accordance with the present invention provides a system and method of physically modulating a digital signal across a medium. A signal is sent one bit at a time (serially) as a period of high voltage followed by a period of low voltage. The present invention includes several major advantages. One advantage is that the code to execute the method is very lightweight. Another advantage is that the signals require no synchronization source. The signals of the present invention function as their own synchronization. |
FILED | Monday, February 20, 2017 |
APPL NO | 15/999841 |
ART UNIT | 2842 — Electrical Circuits and Systems |
CURRENT CPC | Pulse Technique H03K 3/017 (20130101) H03K 5/04 (20130101) H03K 7/06 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11394594 | Pados et al. |
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FUNDED BY |
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APPLICANT(S) | The Research Foundation for The State University of New York (Amherst, New York) |
ASSIGNEE(S) | The Research Foundation for The State University of New York (Amherst, New York) |
INVENTOR(S) | Dimitrios Pados (Amherst, New York); Stella Batalama (Amherst, New York); Georgios Skilvanitis (North Tonawanda, New York); Song-Wen Huang (Amherst, New York) |
ABSTRACT | The present disclosure may be embodied as a transmitter for multiuser multicarrier-chirp-division-multiplexing (“MU-MCDM”) communications. The present disclosure may be embodied as a receive for MU-MCDM communications. The present disclosure may also be embodied as a method for transmitting an MU-MCDM communication signal. The present disclosure may also be embodied as a method for receiving an MU-MCDM communication signal. |
FILED | Monday, September 30, 2019 |
APPL NO | 17/281146 |
ART UNIT | 2632 — Digital Communications |
CURRENT CPC | Transmission H04B 1/7087 (20130101) H04B 2001/6912 (20130101) Multiplex Communication H04J 13/0077 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/0014 (20130101) H04L 27/264 (20130101) Original (OR) Class H04L 27/2639 (20130101) H04L 27/3405 (20130101) H04L 27/26025 (20210101) H04L 2027/0057 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 11389765 | Roy et al. |
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FUNDED BY |
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APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Pratanu Roy (San Ramon, California); Du Nguyen (Fremont, California); Joshuah K. Stolaroff (Oakland, California) |
ABSTRACT | The present disclosure relates to a transport mechanism apparatus for transporting at least one of a gas or a fluid. The transport mechanism may have an inlet, an outlet and a triply periodic minimal surface (TPMS) structure. The TPMS structure is formed in a layer-by-layer three dimensional (3D) printing operation to include cells propagating in three dimensions, where the cells include wall portions having openings, and where the cells form a plurality of flow paths throughout the transport mechanism from the inlet to the outlet, and where the cells form the inlet and the outlet. |
FILED | Wednesday, January 09, 2019 |
APPL NO | 16/243810 |
ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Separation B01D 53/02 (20130101) B01D 53/228 (20130101) Original (OR) Class B01D 67/0032 (20130101) B01D 67/0041 (20130101) B01D 71/022 (20130101) B01D 71/70 (20130101) B01D 2253/202 (20130101) B01D 2253/342 (20130101) B01D 2253/1122 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/28045 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390518 | Black et al. |
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FUNDED BY |
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APPLICANT(S) | Brookhaven Science Associates LLC (Upton, New York) |
ASSIGNEE(S) | Brookhaven Science Associates, LLC (Upton, New York) |
INVENTOR(S) | Charles T. Black (New York, New York); Atikur Rahman (Ridge, New York); Matthew Eisaman (Port Jefferson, New York); Ahsan Ashraf (Port Jefferson, New York) |
ABSTRACT | Technologies are described for methods and systems effective for etching nanostructures in a substrate. The methods may comprise depositing a patterned block copolymer on the substrate. The patterned block copolymer may include first and second polymer block domains. The methods may comprise applying a precursor to the patterned block copolymer to generate an infiltrated block copolymer. The precursor may infiltrate into the first polymer block domain and generate a material in the first polymer block domain. The methods may comprise applying a removal agent to the infiltrated block copolymer to generate a patterned material. The removal agent may be effective to remove the first and second polymer block domains from the substrate. The methods may comprise etching the substrate. The patterned material on the substrate may mask the substrate to pattern the etching. The etching may be performed under conditions to produce nanostructures in the substrate. |
FILED | Tuesday, December 08, 2020 |
APPL NO | 17/114855 |
ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00031 (20130101) Original (OR) Class B81C 1/00111 (20130101) B81C 2201/0132 (20130101) B81C 2201/0149 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Optical Elements, Systems, or Apparatus G02B 1/118 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) G03F 7/405 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 2237/334 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0271 (20130101) H01L 21/0273 (20130101) H01L 21/0337 (20130101) H01L 21/3065 (20130101) H01L 21/3086 (20130101) H01L 31/02363 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11390533 | van Hest et al. |
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FUNDED BY |
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APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); The Regents of the University of Colorado, a Body Corporate (Denver, Colorado) |
INVENTOR(S) | Marinus Franciscus Antonius Maria van Hest (Lakewood, Colorado); David Todd Moore (Arvada, Colorado); Benjia Dou (Cambridge, Massachusetts) |
ABSTRACT | The present disclosure relates to a composition that includes a perovskite crystal, where the perovskite crystal is in the form of a powder, and the perovskite crystal is semiconducting and photovoltaically active. |
FILED | Monday, December 16, 2019 |
APPL NO | 16/715224 |
ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 17/30 (20200101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/34 (20130101) C01P 2002/70 (20130101) C01P 2002/82 (20130101) C01P 2002/84 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11391223 | Robel et al. |
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FUNDED BY |
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APPLICANT(S) | Caterpillar Inc. (Peoria, Illinois) |
ASSIGNEE(S) | Caterpillar Inc. (Peoria, Illinois) |
INVENTOR(S) | Wade James Robel (Dunlap, Illinois); Spencer Landon Huhn (Chillicothe, Illinois); Kevin Weiss (Peoria, Illinois); John Robert McDonald (Peoria, Illinois); Jason Kenneth Bloms (Edwards, Illinois) |
ABSTRACT | A controller may identify an indication to initiate an engine braking procedure associated with an engine of a machine. The controller may obtain, based on identifying the indication to initiate the engine braking procedure, information relating to a requested amount of engine braking power of the engine. The controller may cause one or more components of a variable geometry turbocharger (VGT) of the engine to adjust, and a throttle valve of the engine to adjust, based on the information relating to the requested amount of engine braking power of the engine. |
FILED | Wednesday, August 19, 2020 |
APPL NO | 16/947826 |
ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Internal-combustion Piston Engines; Combustion Engines in General F02B 37/24 (20130101) Controlling Combustion Engines F02D 9/02 (20130101) Original (OR) Class F02D 41/0005 (20130101) F02D 41/0007 (20130101) F02D 41/1446 (20130101) F02D 2009/0222 (20130101) F02D 2009/0242 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11391567 | Thorpe et al. |
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FUNDED BY |
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APPLICANT(S) | Bridger Photonics, Inc. (Bozeman, Montana) |
ASSIGNEE(S) | Bridger Photonics, Inc. (Bozeman, Montana) |
INVENTOR(S) | Michael Thorpe (Bozeman, Montana); Aaron Kreitinger (Bozeman, Montana); Stephen Crouch (Bozeman, Montana) |
ABSTRACT | Measurement approaches and data analysis methods are disclosed for combining 3D topographic data with spatially-registered gas concentration data to increase the efficiency of gas monitoring and leak detection tasks. Here, the metric for efficiency is defined as reducing the measurement time required to achieve the detection, or non-detection, of a gas leak with a desired confidence level. Methods are presented for localizing and quantifying detected gas leaks. Particular attention is paid to the combination of 3D spatial data with path-integrated gas concentration measurements acquired using remote gas sensing technologies, as this data can be used to determine the path-averaged gas concentration between the sensor and points in the measurement scene. Path-averaged gas concentration data is useful for finding and quantifying localized regions of elevated (or anomalous) gas concentration making it ideal for a variety of applications including: oil and gas pipeline monitoring, facility leak and emissions monitoring, and environmental monitoring. |
FILED | Monday, January 06, 2020 |
APPL NO | 16/734769 |
ART UNIT | 2853 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 21/20 (20130101) Original (OR) Class Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 15/00 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 3/28 (20130101) G01M 3/38 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/39 (20130101) G01N 21/53 (20130101) G01N 2021/1793 (20130101) G01N 2021/1795 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 5/00 (20130101) Image or Video Recognition or Understanding G06V 20/64 (20220101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11391651 | Kertesz et al. |
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FUNDED BY |
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APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Vilmos Kertesz (Oak Ridge, Tennessee); Gary J. Van Berkel (Oak Ridge, Tennessee) |
ABSTRACT | A system and method for sampling a sample material includes a device for directing sample into a capture probe. The device for supplying sample material to the probe can be a device for radiating energy to the surface to eject sample from the sample material. A probe includes an outer probe housing having an open end. A liquid supply conduit has an outlet positioned to deliver liquid to the open end. An exhaust conduit removes liquid from the open end of the housing. The liquid supply conduit can be connectable to a liquid supply for delivering liquid at a first volumetric flow rate to the open end of the housing. A liquid exhaust system can be in fluid connection with the liquid exhaust conduit for removing liquid from the liquid exhaust conduit at a second volumetric flow rate such that gas with sample is withdrawn with the liquid. |
FILED | Monday, July 06, 2020 |
APPL NO | 16/921733 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/10 (20130101) G01N 1/24 (20130101) Original (OR) Class G01N 2001/028 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/164 (20130101) H01J 49/0418 (20130101) H01J 49/0463 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11391671 | Mallery et al. |
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FUNDED BY |
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APPLICANT(S) | REBELLION PHOTONICS, INC. (Houston, Texas) |
ASSIGNEE(S) | REBELLION PHOTONICS, INC. (Houston, Texas) |
INVENTOR(S) | Ryan Mallery (Houston, Texas); Ohad Israel Balila (Friendswood, Texas); Robert Timothy Kester (Friendswood, Texas) |
ABSTRACT | An infrared (IR) imaging system for determining a concentration of a target species in an object is disclosed. The imaging system can include an optical system including a focal plane array (FPA) unit behind an optical window. The optical system can have components defining at least two optical channels thereof, said at least two optical channels being spatially and spectrally different from one another. Each of the at least two optical channels can be positioned to transfer IR radiation incident on the optical system towards the optical FPA. The system can include a processing unit containing a processor that can be configured to acquire multispectral optical data representing said target species from the IR radiation received at the optical FPA. One or more of the optical channels may be used in detecting objects on or near the optical window, to avoid false detections of said target species. |
FILED | Thursday, October 22, 2020 |
APPL NO | 16/949255 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/0806 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/314 (20130101) G01N 21/3504 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 5/33 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11391866 | Barton, III et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | David Russell Barton, III (Somerville, Massachusetts); Mark Lawrence (Saint Louis, Missouri); Jennifer A. Dionne (Menlo Park, California); Jefferson Dixon (Staten Island, New York) |
ABSTRACT | High quality factor electromagnetic metasurfaces are provided. The metasurface is configured to have in plane guided-mode resonances (e.g., corresponding to waveguide modes or the like). Coupling features are included in the metasurface that are configured to couple free-space radiation to the guided mode resonances. The resulting structures have a high-Q response to free-space radiation and can be used for various applications, such as beam splitting, beam steering, and beam focusing or defocusing. |
FILED | Wednesday, November 04, 2020 |
APPL NO | 17/089384 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) G02B 1/005 (20130101) Original (OR) Class G02B 6/12 (20130101) G02B 6/26 (20130101) G02B 27/1086 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11392782 | Kan et al. |
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FUNDED BY |
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APPLICANT(S) | Cornell University (Ithaca, New York) |
ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
INVENTOR(S) | Edwin C. Kan (Ithaca, New York); Xiaonan Hui (Ithaca, New York) |
ABSTRACT | The present disclosure provides collaborative radiofrequency identification (RFID) readers that employ code division multiple access (CDMA) encoding to simultaneously broadcast to and read responses from tags in an overlapping reading zone with improved data synchronization and read yield rates. In some embodiments, a harmonic backscattering scheme is used to enable the system to have a much higher signal-to-noise ratio (SNR) and sensitivity, while the reader CDMA protocol can be integrated with an initial TDMA polling process or alternative tag CDMA scheme. |
FILED | Tuesday, May 14, 2019 |
APPL NO | 17/055974 |
ART UNIT | 2699 — Search and Capture Special Detail |
CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/10019 (20130101) Original (OR) Class G06K 19/0724 (20130101) Transmission H04B 5/0031 (20130101) H04B 5/0037 (20130101) H04B 7/216 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11393652 | Neubauer et al. |
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FUNDED BY |
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APPLICANT(S) | Muons, Inc. (Batavia, Illinois) |
ASSIGNEE(S) | Muons, Inc. (Batavia, Illinois) |
INVENTOR(S) | Michael L. Neubauer (San Francisco, California); Alan J. Dudas (Alamo, California); Stephen A. Kahn (Commack, New York) |
ABSTRACT | An anode structure for a magnetron provides for low eddy currents and efficient water cooling. The anode structure may be made by machining a bimetal blank including an out layer of a first metal and an inner layer of a second metal and formed by explosion bonding. The second metal has a resistivity lower than first metal and a thermal conductivity higher than the first metal. The machining may result in the anode structure with vanes each having a center (tip) portion made of the second metal and the rest made of the first metal. The machined anode structure may be coated with the second metal. |
FILED | Friday, January 24, 2020 |
APPL NO | 16/752147 |
ART UNIT | 2879 — Optics |
CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 9/02 (20130101) H01J 23/02 (20130101) Original (OR) Class H01J 25/50 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11393681 | Mane et al. |
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FUNDED BY |
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APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
INVENTOR(S) | Anil U. Mane (Naperville, Illinois); Jeffrey W. Elam (Elmhurst, Illinois) |
ABSTRACT | Transition metal dichalcogenides (TMDs) are deposited by atomic layer deposition as thin layers on a substrate. The TMDs may be grown on oxide substrates and may have a tunable TMD-oxide interface. The TMD may be etched using an atomic layer etching technique. |
FILED | Wednesday, March 06, 2019 |
APPL NO | 16/294797 |
ART UNIT | 2894 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0228 (20130101) H01L 21/0262 (20130101) H01L 21/02205 (20130101) H01L 21/02255 (20130101) H01L 21/02568 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11393976 | Jarillo-Herrero et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
INVENTOR(S) | Pablo Jarillo-Herrero (Cambridge, Massachusetts); Qiong Ma (Cambridge, Massachusetts); Nuh Gedik (Watertown, Massachusetts); Suyang Xu (Cambridge, Massachusetts); Zhiren Zheng (Cambridge, Massachusetts) |
ABSTRACT | An ultrathin, carbon-based memristor with a moiré superlattice potential shows prominent ferroelectric resistance switching. The memristor includes a bilayer material, such as Bernal-stacked bilayer graphene, encapsulated between two layers of a layered material, such as hexagonal boron nitride. At least one of the encapsulating layers is rotationally aligned with the bilayer to create the moiré superlattice potential. The memristor exhibits ultrafast and robust resistance switching between multiple resistance states at high temperatures. The memristor, which may be volatile or nonvolatile, may be suitable for neuromorphic computing. |
FILED | Tuesday, November 10, 2020 |
APPL NO | 17/094141 |
ART UNIT | 2827 — Semiconductors/Memory |
CURRENT CPC | Static Stores G11C 13/0069 (20130101) G11C 2213/35 (20130101) G11C 2213/53 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 45/10 (20130101) Original (OR) Class H01L 45/142 (20130101) H01L 45/143 (20130101) H01L 45/148 (20130101) H01L 45/149 (20130101) H01L 45/1206 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11394020 | Nanda et al. |
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FUNDED BY |
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APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | UT-BATTELLE, LLC (Oakridge, Tennessee) |
INVENTOR(S) | Jagjit Nanda (Knoxville, Tennessee); Ilias Belharouak (Knoxville, Tennessee); Ethan C. Self (Oak Ridge, Tennessee); Devendrasinh Udaisinh Darbar (Cookeville, Tennessee) |
ABSTRACT | A cathode for a lithium battery includes LiNi0.5-x/2Mn0.5-x/2MxO2 where M is at least one selected from the group consisting of Mo, Ti, Cr, Zr and V, and x is between 0.005-0.02. The LiNi0.5-x/2Mn0.5-x/2MxO2 can be coated with Mn2P2O7. The Mn2P2O7 can be 1-3 wt. %, based on the total weight of the LiNi0.5-x/2Mn0.5-x/2MxO2 and Mn2P2O7. A cathode composition, a lithium battery, and a method of making a lithium battery are also disclosed. |
FILED | Friday, June 21, 2019 |
APPL NO | 16/448169 |
ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/131 (20130101) Original (OR) Class H01M 4/366 (20130101) H01M 4/0404 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/625 (20130101) H01M 4/1391 (20130101) H01M 10/0525 (20130101) H01M 2004/028 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11394022 | Xu et al. |
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FUNDED BY |
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APPLICANT(S) | UChicago Argonne, LLC (Chicago, Illinois) |
ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
INVENTOR(S) | Guiliang Xu (Naperville, Illinois); Xiang Liu (Darien, Illinois); Khalil Amine (Oakbrook, Illinois) |
ABSTRACT | A [PxSbyMz]p/[carbon]q composite where x, y, and z represent atomic percentage values and are x>0; y>0; and z≥0, M is an electrically conductive metal, p and q represent the weight percentage values of the composite wherein p and q are in the range of 0-100%, and is p>0. |
FILED | Thursday, April 09, 2020 |
APPL NO | 16/844485 |
ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/364 (20130101) Original (OR) Class H01M 4/587 (20130101) H01M 4/623 (20130101) H01M 10/054 (20130101) H01M 10/0525 (20130101) H01M 10/0569 (20130101) H01M 50/46 (20210101) H01M 2004/021 (20130101) H01M 2300/0028 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11394049 | Tan et al. |
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FUNDED BY |
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APPLICANT(S) | 24M Technologies, Inc. (Cambridge, Massachusetts) |
ASSIGNEE(S) | 24M Technologies, Inc. (Cambridge, Massachusetts) |
INVENTOR(S) | Taison Tan (Pasadena, California); Yet-Ming Chiang (Weston, Massachusetts); Naoki Ota (Lexington, Massachusetts); Throop Wilder (Lincoln, Massachusetts); Mihai Duduta (Somerville, Massachusetts) |
ABSTRACT | Embodiments described herein relate generally to devices, systems and methods of producing high energy density batteries having a semi-solid cathode that is thicker than the anode. An electrochemical cell can include a positive electrode current collector, a negative electrode current collector and an ion-permeable membrane disposed between the positive electrode current collector and the negative electrode current collector. The ion-permeable membrane is spaced a first distance from the positive electrode current collector and at least partially defines a positive electroactive zone. The ion-permeable membrane is spaced a second distance from the negative electrode current collector and at least partially defines a negative electroactive zone. The second distance is less than the first distance. A semi-solid cathode that includes a suspension of an active material and a conductive material in a non-aqueous liquid electrolyte is disposed in the positive electroactive zone, and an anode is disposed in the negative electroactive zone. |
FILED | Tuesday, February 23, 2021 |
APPL NO | 17/182674 |
ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/13 (20130101) H01M 4/38 (20130101) H01M 4/134 (20130101) H01M 4/362 (20130101) H01M 4/386 (20130101) H01M 4/387 (20130101) H01M 4/483 (20130101) H01M 4/587 (20130101) H01M 10/052 (20130101) H01M 10/0525 (20130101) Original (OR) Class H01M 2004/021 (20130101) H01M 2004/023 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/10 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/50 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11394082 | Frischmann et al. |
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FUNDED BY |
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APPLICANT(S) | Sepion Technologies, Inc. (Oakland, California) |
ASSIGNEE(S) | Sepion Technologies, Inc. (Emerville, California) |
INVENTOR(S) | Peter David Frischmann (Oakland, California); Brett Anthony Helms (Oakland, California); Jon-Michael Alessandro (Oakland, California) |
ABSTRACT | Provided are electrochemical cells including separators permeable to some materials and impermeable to other materials in electrolytes. Also provide are methods of forming such separators. The selective permeability of a separator is achieved by its specific pore diameter and a narrow distribution of this diameter. Specifically, a species responsible for ion transport in an electrochemical cell are allowed to pass through the separator, while another species is blocked thereby preventing degradation of the cell. For example, a species containing lithium ions is allowed to pass in rechargeable cells, while one or more species containing transition metals are blocked. In some embodiments, a separator may include a membrane layer with at least 90% of pores of this having a diameter of between about 0.1 nanometers and 1.0 nanometer. The membrane layer may be a standalone layer or supported by a membrane support. |
FILED | Thursday, September 28, 2017 |
APPL NO | 16/335219 |
ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 50/44 (20210101) H01M 50/411 (20210101) Original (OR) Class H01M 50/431 (20210101) H01M 50/449 (20210101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11394091 | Pozin et al. |
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FUNDED BY |
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APPLICANT(S) | DURACELL U.S. OPERATIONS, INC. (Wilmington, Delaware); NATIONAL TECHNOLOGY and ENGINEERING SOLUTIONS OF SANDIA, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | DURACELL U.S. OPERATIONS, INC. (Wilmington, Delaware); NATIONAL TECHNOLOGY and ENGINEERING SOLUTIONS OF SANDIA, LLC (Albuquerque, New Mexico) |
INVENTOR(S) | Michael Pozin (Brookfield, Connecticut); Walter Fred Paxton (Albuquerque, New Mexico); Bryan James Kaehr (Albuquerque, New Mexico) |
ABSTRACT | A battery cell comprising a composite water-responsive safety layer and/or composite water- and pH-responsive safety layer to protect against tissue damage and/or electrolysis, when the battery cell is exposed to aqueous solution or tissue, is provided. The composite water-responsive safety layer and/or composite water- and pH-responsive safety layer is adapted to change from a non-electronically conducting state to an electronically conducting state. |
FILED | Tuesday, March 31, 2020 |
APPL NO | 16/836745 |
ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0427 (20130101) H01M 50/10 (20210101) H01M 50/109 (20210101) H01M 50/116 (20210101) H01M 50/124 (20210101) H01M 50/531 (20210101) H01M 50/543 (20210101) H01M 50/572 (20210101) Original (OR) Class H01M 50/1245 (20210101) H01M 2200/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 11390937 | Manuel et al. |
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FUNDED BY |
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APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida); United States Of America As Represented By The Administrator of NASA (Washington, District of Columbia) |
ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida); UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
INVENTOR(S) | Michele Viola Manuel (Gainesville, Florida); Charles Robert Fisher (Fairfax, Virginia); Maria Clara Wright (Orlando, Florida) |
ABSTRACT | Disclosed herein is a composite comprising a metal alloy matrix; where the metal alloy matrix comprises aluminum in an amount greater than 50 atomic percent; a first metal and a second metal; where the first metal is different from the second metal; and where the metal alloy matrix comprises a low temperature melting phase and a high temperature melting phase; where the low temperature melting phase melts at a temperature that is lower than the high temperature melting phase; and a contracting constituent; where the contracting constituent exerts a compressive force on the metal alloy matrix at a temperature between a melting point of the low temperature melting phase and a melting point of the high temperature melting phase or below the melting points of the high and low temperature melting phases. |
FILED | Tuesday, February 11, 2020 |
APPL NO | 16/787823 |
ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 19/00 (20130101) B22D 21/007 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0003 (20130101) B22F 2301/15 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 15/20 (20130101) B32B 2307/54 (20130101) Alloys C22C 1/0416 (20130101) C22C 1/1036 (20130101) C22C 1/1084 (20130101) C22C 21/02 (20130101) C22C 21/14 (20130101) C22C 49/06 (20130101) C22C 49/14 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/006 (20130101) Original (OR) Class C22F 1/043 (20130101) C22F 1/057 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11391356 | Hu et al. |
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FUNDED BY |
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APPLICANT(S) | Sikorsky Aircraft Corporation (Stratford, Connecticut) |
ASSIGNEE(S) | Sikorsky Aircraft Corporation (Stratford, Connecticut) |
INVENTOR(S) | Wei Hu (Milford, Connecticut); Shane Lewis (Honey Brook, Pennsylvania); Bruce D. Hansen (Shelton, Connecticut); Bryan Kenneth Baskin (Arlington, Texas) |
ABSTRACT | A hybrid gear includes a first portion having a plurality of first engagement features formed from a first material and having a first stiffness and a second portion having a plurality of second engagement features in intermeshing arrangement with the plurality of first engagement features. The plurality of second engagement features is formed from a second material distinct from the first material and having a second stiffness. The first stiffness of the plurality of first engagement features is within 20% of the second stiffness of the plurality of second engagement features. |
FILED | Wednesday, July 17, 2019 |
APPL NO | 16/514213 |
ART UNIT | 3658 — Material and Article Handling |
CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 35/00 (20130101) Gearing F16H 55/06 (20130101) F16H 55/14 (20130101) Original (OR) Class F16H 55/17 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11391493 | Hasegawa et al. |
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FUNDED BY |
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APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
INVENTOR(S) | Mark M. Hasegawa (Highland, Maryland); Kenneth O'Connor (Greenbelt, Maryland) |
ABSTRACT | A space-stable thin film composite coating is provided that exhibits high IR emittance properties similar to OSR mirrors, and which is thin enough to be applied to a flexible substrate. The composite coating can include hundreds of alternating layers of aluminum oxide and silicon dioxide vacuum deposited to individual layer thickness of about 150 Angstroms and 50 Angstroms, respectively. The composite coating can be attached to substrates having complex geometries, for example, at various points during integration and production of hardware. The thin film can increase thermal design efficiency, reduce radiator mass and costs, and reduce production time-frames by eliminating the complexity of OSR mirror bonding. |
FILED | Wednesday, September 19, 2018 |
APPL NO | 16/135812 |
ART UNIT | 1783 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/00865 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 15/20 (20130101) Solar Heat Collectors; Solar Heat Systems F24S 23/82 (20180501) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 1/12 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24967 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11391672 | Aslam et al. |
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FUNDED BY |
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APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
INVENTOR(S) | Shahid Aslam (Washington, District of Columbia); Daniel P. Glavin (Greenbelt, Maryland); Gerard T. Quilligan (Gulf Breeze, Florida); Nicolas Gorius (Washington, District of Columbia); Perry A. Gerakines (Greenbelt, Maryland); John R. Kolasinski (Greenbelt, Maryland); Dat Tran (Washington, District of Columbia); Todd C. Purser (Greenbelt, Maryland) |
ABSTRACT | An apparatus for measuring vapor partial pressures of water and carbon dioxide includes a pair of infrared (IR) sources and a pair of quad filter detectors are placed opposite to one another such that the vapor partial pressures of water (H2O) and carbon dioxide (CO2) is measured and quantified in a short pathlength gas cell. |
FILED | Tuesday, August 25, 2020 |
APPL NO | 17/002209 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 11/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/2205 (20130101) G01N 21/3504 (20130101) G01N 21/3518 (20130101) Original (OR) Class G01N 2201/0633 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11394168 | Yu et al. |
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FUNDED BY |
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APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
INVENTOR(S) | Anthony Yu (Greenbelt, Maryland); Kenji Numata (Greenbelt, Maryland) |
ABSTRACT | A master oscillator configured as a seed laser for a laser optical module includes a reduced size, temperature controlled non-planar ring oscillator, a piezo-electric transducer mounted on the non-planar ring oscillator, a pump laser diode, and coupling optics configured to couple a laser output of the pump laser diode to an end face of the non-planar ring oscillator. The pump laser diode may operate as a single-mode pump. |
FILED | Wednesday, June 05, 2019 |
APPL NO | 16/432601 |
ART UNIT | 2828 — Semiconductors/Memory |
CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/083 (20130101) H01S 3/102 (20130101) H01S 3/105 (20130101) H01S 3/0606 (20130101) H01S 3/0615 (20130101) H01S 3/0617 (20130101) H01S 3/0627 (20130101) H01S 3/0941 (20130101) H01S 3/1022 (20130101) H01S 3/1028 (20130101) Original (OR) Class H01S 3/1312 (20130101) H01S 3/1611 (20130101) H01S 3/1623 (20130101) H01S 3/1643 (20130101) H01S 3/1696 (20130101) H01S 3/2308 (20130101) H01S 3/2375 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
US 11392949 | Boyd et al. |
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FUNDED BY |
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APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
ASSIGNEE(S) | The Government of the United States of America, as represented bv the Secretary of Homeland Security (Washington, District of Columbia) |
INVENTOR(S) | Daniel A. Boyd (Arlington, Virginia); Kelli L. Biegger (McLean, Virginia); Chang Ellison (Arlington, Virginia); Jason Lim (Alexandria, Virginia) |
ABSTRACT | A method for verifying an identity of an individual as a first party via a first party system by a second party system comprises: sending a request for identification information of the first party; receiving first party information associated with a mobile identification credential (MIC) which the first party system received from an authorizing party system (APS) before the second party system sends the request for identification information of the first party to the first party system, the first party having consented to release the first party information to the second party system, and the first party information having been verified by the APS before the APS sends the MIC to the first party system; using the verified first party information associated with the MIC to verify or not verify an identity of the first party; verifying the identity of the first party before providing services to the first party. |
FILED | Friday, November 19, 2021 |
APPL NO | 17/531194 |
ART UNIT | 2887 — Optics |
CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 20/065 (20130101) G06Q 20/409 (20130101) G06Q 20/3827 (20130101) G06Q 20/4014 (20130101) Original (OR) Class G06Q 20/38215 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11392951 | Boyd et al. |
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FUNDED BY |
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APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
INVENTOR(S) | Daniel Boyd (Arlington, Virginia); Arun Vemury (North Bethesda, Maryland) |
ABSTRACT | Systems and methods and an example method including storing, in an access control memory of an access control computer system a set of access control identity records, receiving from an individual a proffered biographic information, and comparing the proffered biographic information to the access control identity records. In response to the comparing indicating a subset of than one access control identity records having biographic information having similarity to the proffered biographic information exceeding a threshold, generating and sending to a central resource computer system a biometric comparison request. The request includes the proffered biographic information of the persons, an indication of the biometric information of the person, and indication of biographic information in the identity records in the subset. A response is received from the central resource computer indicating whether a central resource identity record includes both a matching identity record biographic information and a matching identity record biometric information. |
FILED | Friday, September 17, 2021 |
APPL NO | 17/478552 |
ART UNIT | 3696 — Business Methods - Finance/Banking/ Insurance |
CURRENT CPC | Electric Digital Data Processing G06F 16/22 (20190101) G06F 21/32 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/06037 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 20/40145 (20130101) Original (OR) Class G06Q 50/265 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
US 11392016 | Grunwald et al. |
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FUNDED BY |
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APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
INVENTOR(S) | David Grunwald (Worcester, Massachusetts); Maximiliaan Huisman (Brookfield, Massachusetts); Carlas Smith (Delft, Netherlands) |
ABSTRACT | The described embodiments are directed to a system and methods of calibrating a fluorescence microscope and/or light detection device using a calibrating apparatus. The apparatus may comprise a main body housing, a sensor head, and a microcontroller assembly disposed within the housing. The housing may include an adapter to mechanically couple the housing to a microscope. The sensor head may comprise (i) an optical power sensor to produce a power signal representative of an optical power magnitude of light applied to the optical power sensor, (ii) an optical wavelength sensor configured to produce wavelength information associated with the light applied to the optical wavelength sensor, and (iii) a light source configured to direct light toward a detection device associated with the microscope. The microcontroller assembly may be configured to generate an optical power magnitude value based on the power signal and adjusted according to the wavelength information. |
FILED | Tuesday, October 13, 2020 |
APPL NO | 17/069335 |
ART UNIT | 2878 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/008 (20130101) G02B 21/0032 (20130101) G02B 21/361 (20130101) G02B 21/362 (20130101) Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor G03B 21/204 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11393974 | Agarwal et al. |
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FUNDED BY |
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APPLICANT(S) | Signal Solutions, LLC (Lexington, Kentucky) |
ASSIGNEE(S) | Signal Solutions, LLC (Lexington, Kentucky) |
INVENTOR(S) | Anuj Agarwal (Lexington, Kentucky); Michael E. Lhamon (Lexington, Kentucky) |
ABSTRACT | Sensing an environment by confining a monitored live subject in an enclosure, detecting an effect on a coaxial piezoelectric cable resulting from the monitored live subject, wherein the coaxial piezoelectric cable is located at least proximate to the enclosure, and deriving information about a state of the monitored live subject based on the detected effect. |
FILED | Tuesday, October 13, 2020 |
APPL NO | 17/069419 |
ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 29/005 (20130101) Diagnosis; Surgery; Identification A61B 5/113 (20130101) A61B 5/0816 (20130101) A61B 5/4812 (20130101) A61B 5/4818 (20130101) A61B 5/6888 (20130101) A61B 5/6892 (20130101) A61B 2503/40 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/45 (20130101) Original (OR) Class H01L 41/087 (20130101) H01L 41/193 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
US 11391562 | Nguyen et al. |
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FUNDED BY |
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APPLICANT(S) | iSenseCloud, Inc. (San Jose, California) |
ASSIGNEE(S) | iSenseCloud, Inc. (Milpitas, California) |
INVENTOR(S) | An-Dien Nguyen (Fremont, California); An H. Nguyen (Fremont, California) |
ABSTRACT | A fiber optic voltage conditioner, and method therefor, generally relate to voltage conditioning. In such a fiber optic voltage conditioner, there is a laser, and an optical circulator is coupled to receive a light signal from the laser. A controller is coupled to the laser and is configured to generate first control information for wavelength-drift control of the laser. A data acquisition module is coupled to the controller and is configured to generate second control information for the controller for adjustment of the first control information. A photodetector is coupled to the optical circulator to receive a returned optical signal and is coupled to the data acquisition module to provide an analog output signal thereto. The photodetector is configured to generate the analog output signal responsive to the returned optical signal. The data acquisition module is configured to generate the second control information using the analog output signal. |
FILED | Thursday, February 20, 2020 |
APPL NO | 16/796447 |
ART UNIT | 2828 — Semiconductors/Memory |
CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/165 (20130101) Original (OR) Class Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/3206 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/0612 (20130101) H01S 5/0617 (20130101) H01S 5/0622 (20130101) H01S 5/0687 (20130101) H01S 5/02415 (20130101) H01S 5/4087 (20130101) H01S 5/06804 (20130101) H01S 5/06808 (20130101) H01S 5/06837 (20130101) Transmission H04B 10/572 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11394082 | Frischmann et al. |
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FUNDED BY |
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APPLICANT(S) | Sepion Technologies, Inc. (Oakland, California) |
ASSIGNEE(S) | Sepion Technologies, Inc. (Emerville, California) |
INVENTOR(S) | Peter David Frischmann (Oakland, California); Brett Anthony Helms (Oakland, California); Jon-Michael Alessandro (Oakland, California) |
ABSTRACT | Provided are electrochemical cells including separators permeable to some materials and impermeable to other materials in electrolytes. Also provide are methods of forming such separators. The selective permeability of a separator is achieved by its specific pore diameter and a narrow distribution of this diameter. Specifically, a species responsible for ion transport in an electrochemical cell are allowed to pass through the separator, while another species is blocked thereby preventing degradation of the cell. For example, a species containing lithium ions is allowed to pass in rechargeable cells, while one or more species containing transition metals are blocked. In some embodiments, a separator may include a membrane layer with at least 90% of pores of this having a diameter of between about 0.1 nanometers and 1.0 nanometer. The membrane layer may be a standalone layer or supported by a membrane support. |
FILED | Thursday, September 28, 2017 |
APPL NO | 16/335219 |
ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 50/44 (20210101) H01M 50/411 (20210101) Original (OR) Class H01M 50/431 (20210101) H01M 50/449 (20210101) |
VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
US 11390473 | Perry-Eaton et al. |
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FUNDED BY |
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APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
INVENTOR(S) | Wayne R. Perry-Eaton (Leesburg, Virginia); George W. Potts, Jr. (Upper Marlboro, Maryland); Daniel Radtke (Madison, Wisconsin) |
ABSTRACT | An automated system for transferring articles from a container. An item transfer system includes a frame configured to receive a first tray and a second tray, a movable paddle assembly, a frame, and a plurality of actuators. The system is configured to transfer articles from the first tray to the second tray by an automated process including securing the articles within the first tray with the paddle assembly, moving a lifting assembly or an item support platform such that the articles are in a slidable configuration relative to the first tray, moving the paddle assembly and/or the item support platform in one or more linear translations to remove the items from the first tray and place the items above the second tray, and releasing the items into the second tray. |
FILED | Friday, May 08, 2020 |
APPL NO | 16/870605 |
ART UNIT | 3653 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 3/008 (20130101) Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors B65G 65/04 (20130101) Original (OR) Class B65G 65/38 (20130101) B65G 2207/46 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11392141 | Dinh |
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FUNDED BY |
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APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
INVENTOR(S) | Han Truong Dinh (Falls Church, Virginia) |
ABSTRACT | Systems and methods for coordinating container transportation. A method of autonomously transporting a cargo container includes aligning a distribution vehicle with the cargo container. The distribution vehicle is aligned with and hitched to the cargo container. An attachment can be connected to the cargo container for mating systems of the cargo container with the distribution vehicle. A system has inputs for vehicle and container location, arrival and departure times, facility plans, and can coordinate the autonomous movement of containers in a facility or a yard. |
FILED | Friday, January 17, 2020 |
APPL NO | 16/746606 |
ART UNIT | 3666 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Arrangements of Heating, Cooling, Ventilating or Other Air-treating Devices Specially Adapted for Passenger or Goods Spaces of Vehicles B60H 1/00507 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/104 (20130101) G05D 1/0297 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0832 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
US 11390653 | Tullman et al. |
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FUNDED BY |
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APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
INVENTOR(S) | Jennifer A. Tullman (Germantown, Maryland); Zvi Kelman (Gaithersburg, Maryland); John P. Marino (Silver Spring, Maryland) |
ABSTRACT | An amino acid-specific binder selectively binds to a binding amino acid. A binder complex selectively identifies the binding amino acid and includes an adjunct attached to the amino acid-specific binder. The adjunct includes a taggant, protein, substrate, or chemical modifier. Selectively identifying an N-terminal amino acid includes anchoring a C-terminal end; contacting an N-terminal amino acid of the anchored analyte with the binder complex; selectively binding when the N-terminal amino acid includes the binding amino acid; producing, by the taggant of the tagged complex, a taggant signal; detecting the taggant signal; and identifying the N-terminal amino acid based on the taggant signal. |
FILED | Thursday, August 06, 2020 |
APPL NO | 16/986334 |
ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Peptides C07K 1/13 (20130101) C07K 14/195 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of State (DOS)
US 11390886 | Jin et al. |
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FUNDED BY |
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APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
INVENTOR(S) | Shengkan Jin (Belle Mead, New Jersey); Juan-Carlos Collantes (Princeton, New Jersey) |
ABSTRACT | The present invention discloses a system for targeted gene editing and related uses. |
FILED | Friday, July 15, 2016 |
APPL NO | 15/744505 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/102 (20130101) C12N 15/902 (20130101) Original (OR) Class C12N 2310/20 (20170501) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
US 11391288 | Miller et al. |
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FUNDED BY |
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APPLICANT(S) | General Electric Company (Schenectady, New York) |
ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
INVENTOR(S) | Kyle Louis Miller (Cincinnati, Ohio); Andrew Breeze-Stringfellow (Montgomery, Ohio) |
ABSTRACT | A turbo machine, a computer-implemented method, and a computer system for operating a compressor assembly are provided. The method includes comparing a first data set and a second data set to determine a first correlation factor, comparing the first correlation factor to a first threshold that at least partially determines whether a stall precursor exists, removing mean values from the first data set and the second data set, comparing the first data set and the second data set each removed of mean values to determine a second correlation factor, and comparing the second correlation factor to the first threshold, and classifying the stall precursor as either a spike stall precursor, a modal stall precursor, or a combination stall precursor. |
FILED | Wednesday, September 09, 2020 |
APPL NO | 17/015400 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive-displacement Pumps F04D 27/001 (20130101) Original (OR) Class F04D 27/02 (20130101) Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G F05B 2220/302 (20130101) F05B 2270/301 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2270/101 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
US 11390540 | Viswanathan |
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FUNDED BY |
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APPLICANT(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
ASSIGNEE(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
INVENTOR(S) | Tito Viswanathan (Little Rock, Arkansas) |
ABSTRACT | The present disclosure relates to water purification compositions and the method of producing the same. Specifically, the present disclosure relates to a method of producing a water purification composition including providing a substrate having one or more functional groups that has hydroxyl, thiol, carboxyl, and/or amino group; depositing a solution of a metal salt on the substrate; depositing a solution of carboxylic acid compound on the substrate; forming a mixture wherein the metal cross-links the hydroxyl, thiol, carboxyl and/or amino groups on the surface of the substrate, and the carboxylic acid compound; and heating the mixture till the product is dry. |
FILED | Tuesday, July 28, 2020 |
APPL NO | 16/940496 |
ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/0203 (20130101) B01J 41/09 (20170101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/42 (20130101) Original (OR) Class C02F 1/281 (20130101) C02F 1/288 (20130101) C02F 2001/422 (20130101) C02F 2101/14 (20130101) C02F 2101/20 (20130101) C02F 2101/103 (20130101) C02F 2101/105 (20130101) C02F 2101/106 (20130101) C02F 2103/001 (20130101) C02F 2103/10 (20130101) C02F 2305/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
US 11393974 | Agarwal et al. |
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FUNDED BY |
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APPLICANT(S) | Signal Solutions, LLC (Lexington, Kentucky) |
ASSIGNEE(S) | Signal Solutions, LLC (Lexington, Kentucky) |
INVENTOR(S) | Anuj Agarwal (Lexington, Kentucky); Michael E. Lhamon (Lexington, Kentucky) |
ABSTRACT | Sensing an environment by confining a monitored live subject in an enclosure, detecting an effect on a coaxial piezoelectric cable resulting from the monitored live subject, wherein the coaxial piezoelectric cable is located at least proximate to the enclosure, and deriving information about a state of the monitored live subject based on the detected effect. |
FILED | Tuesday, October 13, 2020 |
APPL NO | 17/069419 |
ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 29/005 (20130101) Diagnosis; Surgery; Identification A61B 5/113 (20130101) A61B 5/0816 (20130101) A61B 5/4812 (20130101) A61B 5/4818 (20130101) A61B 5/6888 (20130101) A61B 5/6892 (20130101) A61B 2503/40 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/45 (20130101) Original (OR) Class H01L 41/087 (20130101) H01L 41/193 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 11394588 | Robinson |
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FUNDED BY |
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APPLICANT(S) | Rampart Communications, Inc. (Annapolis, Maryland) |
ASSIGNEE(S) | Rampart Communications, Inc. (Annapolis, Maryland) |
INVENTOR(S) | Matthew Brandon Robinson (Crownsville, Maryland) |
ABSTRACT | A system includes first and second sets of communication devices. A processor coupled to the first set of communication devices produces a first encoded vector and transmits the first encoded vector to the second set of communication devices via a communication channel that applies a channel transformation to the first encoded vector during transmission. A processor coupled to the second set of communication devices receives the transformed signal, detects an effective channel thereof, and identifies left and right singular vectors of the effective channel. A precoding matrix is selected from a codebook of unitary matrices based on a message, and a second encoded vector is produced based on a second known vector, the precoding matrix, a complex conjugate of the left singular vectors, and the right singular vectors. The second encoded vector is sent to the first set of communication devices for identification of the message. |
FILED | Thursday, January 28, 2021 |
APPL NO | 17/161118 |
ART UNIT | 2633 — Digital Communications |
CURRENT CPC | Transmission H04B 7/0413 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 25/0391 (20130101) Original (OR) Class H04L 27/2602 (20130101) Wireless Communication Networks H04W 12/03 (20210101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11394727 | Payton |
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FUNDED BY |
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APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
ASSIGNEE(S) | HRL LABORATORIES, LLC (Malibu, California) |
INVENTOR(S) | David W. Payton (Calabasas, California) |
ABSTRACT | Described is a system for side-channel based detection of cyber-attack. In operation, the system converts data bus signals from a platform (e.g., vehicular platform) into a first time series of system states. The system further converts analog side-channel signals from the platform into a second time-series of system states. Anomalous behavior of the platform is detected by comparing the first time series of system states with the second time series of system states to identify violations of predetermined constraints. Upon detection, the anomalous behavior is designated as a cyber-attack of the platform, which causes the platform to initiate an action based on the detected cyber-attack. Such actions include implementing a safe made, etc. |
FILED | Thursday, December 13, 2018 |
APPL NO | 16/219749 |
ART UNIT | 2497 — Cryptography and Security |
CURRENT CPC | Electric Digital Data Processing G06F 21/85 (20130101) G06F 21/755 (20170801) Transmission of Digital Information, e.g Telegraphic Communication H04L 12/40 (20130101) H04L 63/1416 (20130101) Original (OR) Class H04L 63/1425 (20130101) H04L 63/1441 (20130101) H04L 67/12 (20130101) H04L 69/08 (20130101) H04L 2012/40215 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, July 19, 2022.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20220719.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page