FedInvent™ Patents

Patent Details for Tuesday, July 19, 2022 

This page was updated on Wednesday, July 20, 2022 at 06:31 AM GMT

Department of Health and Human Services (HHS) 

US 11389095 Rehan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) Los Angeles BioMedical Research Institute at Harbor UCLA Medical Center (Torrance, California);  Intelligent Optical Systems (Torrance, California)
ASSIGNEE(S) Los Angeles BioMedical Research Institute at Harbor UCLA Medical Center (Torrance, California);  Intelligent Optical Systems (Torrance, California)
INVENTOR(S) Virender Rehan (Torrance, California);  Jesus Delgado (Torrance, California)
ABSTRACT Embodiments described herein relate to a catheter configured to detect at least one blood gas parameter present in blood in an artery of a patient, including, but not limited to, a catheter wall forming at least one lumen configured for umbilical arterial catheterization, at least one optical fiber incorporated in the catheter wall, wherein the at least one optical fiber is configured to detected the at least one blood gas parameter.
FILED Thursday, July 27, 2017
APPL NO 16/321798
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/01 (20130101)
A61B 5/1459 (20130101)
A61B 5/4839 (20130101)
A61B 5/6852 (20130101)
A61B 5/14539 (20130101)
A61B 5/14552 (20130101)
A61B 5/14557 (20130101) Original (OR) Class
A61B 5/150038 (20130101)
A61B 2503/045 (20130101)
A61B 2505/03 (20130101)
A61B 2562/0233 (20130101)
A61B 2562/0271 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389106 Porges et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH Office of the Director (NIHOD)
APPLICANT(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida);  Johns Hopkins University, The (Baltimore, Maryland)
ASSIGNEE(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida);  The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Eric C. Porges (Gainesville, Florida);  Damon Lamb (Gainesville, Florida);  Martha Campbell Thompson (Micanopy, Florida);  Richard Edden (Baltimore, Maryland)
ABSTRACT Aspects of the disclosure relate to systems and methods for obtaining and interpreting magnetic resonance spectroscopy (MRS) data obtained from the pancreas of a subject. In some embodiments, systems and methods of the disclosure relate to analyzing MRS spectra of metabolites, for example y-Aminobutyric acid (GABA), to assess pancreatic islet density and function in a subject. In some embodiments, systems and methods described by the disclosure are useful for the diagnosis and/or treatment of diseases associated with impaired pancreatic function, for example diabetes.
FILED Wednesday, October 17, 2018
APPL NO 16/756489
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101)
A61B 5/425 (20130101) Original (OR) Class

Preparations for Medical, Dental, or Toilet Purposes
A61K 31/155 (20130101)
A61K 38/28 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/485 (20130101)
G01R 33/3415 (20130101)
G01R 33/4616 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389127 Sahbaee Bagherzadeh et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Siemens Healthcare GmbH (Erlangen, Germany);  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland)
ASSIGNEE(S) Siemens Healthcare GmbH (Erlangen, Germany);  The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Pooyan Sahbaee Bagherzadeh (Mount Pleasant, South Carolina);  Babak Saboury Sichani (Laurel, Maryland);  Faraz Farhadi (Fairfax, Virginia)
ABSTRACT A virtual 511 KeV attenuation map is generated from CT data. Spectral or multiple energy CT is used to more accurately extrapolate the 511 KeV attenuation map. Since spectral or multiple energy CT may allow for material decomposition and/or due to additional information in the form of measurements at different energies, the modeling used to generate the 511 KeV attenuation map may better account for all materials including high density material. The extrapolated 511 KeV attenuation map may more likely represent actual attenuation at 511 KeV without requiring extra scanning using a 511 KeV source external to the patient. The virtual 511 KeV attenuation map (e.g., CT data at 511 KeV) may provide more accurate PET image reconstruction.
FILED Monday, September 30, 2019
APPL NO 16/587789
ART UNIT 2884 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/037 (20130101)
A61B 6/481 (20130101)
A61B 6/4417 (20130101) Original (OR) Class

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 2005/1098 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/046 (20130101)
G01N 2223/3303 (20130101)
G01N 2223/6126 (20130101)

Image Data Processing or Generation, in General
G06T 11/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389399 Bellinger et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) Andrew Bellinger (Wellesley, Massachusetts);  Shiyi Zhang (Shanghai, China PRC);  Carlo Giovanni Traverso (Newton, Massachusetts);  Robert S. Langer (Newton, Massachusetts);  Stacy Mo (Darien, Illinois);  Tyler Grant (Arlington, Massachusetts);  Mousa Jafari (Waltham, Massachusetts);  Dean Liang Glettig (Cambridge, Massachusetts);  Angela DiCiccio (San Francisco, California);  Lowell L. Wood, Jr. (Bellevue, Washington);  Philip A. Eckhoff (Kirkland, Washington)
ABSTRACT Certain embodiments comprise administering a residence structure to a subject (e.g., a patient) such that the residence structure is retained at a location internal to the subject for a particular amount of time (e.g., at least about 24 hours) before being released. In certain embodiments, the structure has a modular design, combining a material configured for controlled release of therapeutic, diagnostic, and/or enhancement agents with a structural material necessary for gastric residence but configured for controlled and/or tunable degradation/dissolution to determine the time at which retention shape integrity is lost and the structure passes out of the gastric cavity. For example, in certain embodiments, the residence structure comprises a first elastic component, a second component configured to release an active substance, and, optionally, a linker. In some such embodiments, the linker may be configured to degrade.
FILED Friday, December 18, 2020
APPL NO 17/126835
ART UNIT 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/48 (20130101)
A61K 9/0053 (20130101)
A61K 9/0065 (20130101) Original (OR) Class
A61K 31/65 (20130101)
A61K 31/357 (20130101)
A61K 31/7048 (20130101)
A61K 47/10 (20130101)
A61K 47/32 (20130101)
A61K 47/34 (20130101)
A61K 47/40 (20130101)
A61K 47/42 (20130101)
A61K 47/58 (20170801)
A61K 47/6901 (20170801)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 31/002 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 18/73 (20130101)
C08G 18/4277 (20130101)
C08G 63/08 (20130101)
C08G 83/006 (20130101)
C08G 2230/00 (20130101)

Compositions of Macromolecular Compounds
C08L 33/02 (20130101)
C08L 33/08 (20130101)
C08L 33/14 (20130101)
C08L 2203/02 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389414 Linton et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) Macrae F. Linton (Nashville, Tennessee);  John A. Oates (Nashville, Tennessee);  Sean S. Davies (Nashville, Tennessee);  L. Jackson Roberts, II (Gallatin, Tennessee);  Venkataraman Amarnath (Brentwood, Tennessee);  Patricia G. Yancey (Nashville, Tennessee);  Huan Tao (Nashville, Tennessee)
ABSTRACT A method of treating atherosclerosis, comprising administering to a patient in need there of an effective gamma-ketoaldehyde scavenging amount of a gamma-ketoaldehyde scavenging compound.
FILED Friday, April 27, 2018
APPL NO 16/607700
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/135 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/10 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389415 Wainer et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland);  Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Irving W. Wainer (Washington, District of Columbia);  Michel Bernier (Pikesville, Maryland);  Rajib K. Paul (Baltimore, Maryland)
ABSTRACT This disclosure concerns the discovery of the use of fenoterol analogues for regulating cannabinoid (CB) receptor activity-related disorders and disease, such as dysregulated CB receptors, including treating a disorder or disease, such as a glioblastoma, hepatocellular carcinoma, liver cancer, colon cancer, and/or lung cancer, which is associated with altered cannabinoid receptor activity. In one example, the method includes administering to a subject having or at risk of developing a disorder or disease regulated by CB receptor activity an effective amount of a fenoterol analogue to reduce one or more symptoms associated with the disorder or disease regulated by CB receptor activity.
FILED Thursday, August 13, 2020
APPL NO 16/992742
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/05 (20130101)
A61K 31/137 (20130101) Original (OR) Class
A61K 45/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389422 Lin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The University of Chicago (Chicago, Illinois)
ASSIGNEE(S) The University of Chicago (Chicago, Illinois)
INVENTOR(S) Wenbin Lin (Chicago, Illinois);  Christina Chan (Chicago, Illinois);  Wenbo Han (Chicago, Illinois)
ABSTRACT Nanoparticles comprising micheliolide (MCL) or derivatives thereof, and optionally additional therapeutic agents, such as chemotherapeutic agents, are described. Also described are methods of treating diseases, such as cancer, comprising the use of combinations of MCL or a derivative thereof with X-ray irradiation and/or other therapeutic agents, such as immune checkpoint inhibitors. The use of the combinations can provide synergistic anticancer therapeutic efficacy, for example, as the MCL or derivative thereof can both sensitize cancer cells to therapy and target resistant cancer stem cells (CSCs) for selective cell death.
FILED Monday, April 27, 2020
APPL NO 16/859594
ART UNIT 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/343 (20130101) Original (OR) Class
A61K 45/06 (20130101)
A61K 47/6803 (20170801)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/10 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
A61P 37/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389427 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio);  SAINT LOUIS UNIVERSITY (St. Louis, Missouri)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) Lilei Zhang (Cleveland Heights, Ohio);  Mukesh K. Jain (Solon, Ohio);  Thomas Burris (Columbia, Illinois)
ABSTRACT A method of treating cardiac hypertrophy and/or heart failure in a subject includes administering to the subject a therapeutically effective amount of a REV-ERBα agonist.
FILED Friday, February 09, 2018
APPL NO 16/485359
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/0053 (20130101)
A61K 31/381 (20130101)
A61K 31/4025 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389430 Raffay et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) Thomas M. Raffay (Cleveland, Ohio);  Benjamin M. Gaston (Cleveland, Ohio)
ABSTRACT A method of treating a hyperoxia induced disease or disorder associated with GSNO deficiency in a subject in need thereof includes administering to the subject a therapeutically effective amount of GSNO or a GSNO promoting agent.
FILED Tuesday, January 21, 2020
APPL NO 16/748588
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/0078 (20130101)
A61K 31/4178 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389439 John et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) The Jackson Laboratory (Bar Harbor, Maine)
ASSIGNEE(S) The Jackson Laboratory (Bar Harbor, Maine)
INVENTOR(S) Simon W. M. John (Bar Harbor, Maine);  Peter Alexander Williams (Tremont, Maine)
ABSTRACT The invention relates to the use of a pharmaceutical composition containing nicotinamide (NAM) and/or pyruvate as a neuroprotective medicament or gene therapy in the treatment of neurodegenerative disorders, in particular axon degeneration of neuronal tissue in ocular-related neurodegeneration diseases including glaucoma.
FILED Monday, April 23, 2018
APPL NO 15/959379
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/19 (20130101)
A61K 31/19 (20130101)
A61K 31/455 (20130101) Original (OR) Class
A61K 31/455 (20130101)
A61K 31/706 (20130101)
A61K 31/706 (20130101)
A61K 31/4745 (20130101)
A61K 31/4745 (20130101)
A61K 38/00 (20130101)
A61K 38/45 (20130101)
A61K 45/06 (20130101)
A61K 48/00 (20130101)
A61K 48/005 (20130101)
A61K 48/0075 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 27/06 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2750/14143 (20130101)

Enzymes
C12Y 207/07001 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389455 Andrake et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Institute for Cancer Research (Philadelphia, Pennsylvania)
ASSIGNEE(S) Institute for Cancer Research (Philadelphia, Pennsylvania)
INVENTOR(S) Mark D. Andrake (Philadelphia, Pennsylvania);  Anna Marie Skalka (Philadelphia, Pennsylvania);  George W. Merkel (Philadelphia, Pennsylvania)
ABSTRACT The disclosure generally relates to compounds, compositions, and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV-1 integrase, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection.
FILED Wednesday, December 30, 2020
APPL NO 17/138581
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/53 (20130101) Original (OR) Class
A61K 31/454 (20130101)
A61K 31/4245 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389459 Sessler et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Jonathan L. Sessler (Austin, Texas);  Jonathan Arambula (Austin, Texas);  Zahid H. Siddik (Houston, Texas);  Gregory Thiabaud (Austin, Texas)
ABSTRACT The present disclosure relates platinum(IV) and texaphyrin linked conjugates and compositions comprising a texaphyrin and a platinum(IV) agent. The present disclosure also provides pharmaceutical compositions of the conjugates and compositions. Also, provided herein are methods of using the instant compounds in the treatment of cancer such as a platinum resistant cancer.
FILED Friday, September 06, 2019
APPL NO 16/563714
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/555 (20130101) Original (OR) Class
A61K 47/60 (20170801)
A61K 47/546 (20170801)
A61K 47/547 (20170801)
A61K 49/10 (20130101)
A61K 49/085 (20130101)
A61K 49/106 (20130101)

Heterocyclic Compounds
C07D 487/22 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 15/0093 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389460 Dellinger
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) City of Hope (Duarte, California)
ASSIGNEE(S) CITY OF HOPE (Duarte, California)
INVENTOR(S) Thanh Dellinger (Azusa, California)
ABSTRACT Provided herein are, inter alia, methods and compositions for treating cancer in a subject in need thereof comprising a therapeutically effective amount of a stilbenoid compound and a progestin.
FILED Friday, September 14, 2018
APPL NO 16/131985
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/08 (20130101)
A61K 9/10 (20130101)
A61K 9/48 (20130101)
A61K 9/0053 (20130101)
A61K 9/0095 (20130101)
A61K 9/2004 (20130101)
A61K 31/09 (20130101)
A61K 31/57 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389465 Sherwood et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) VANDERBILT UNIVERSITY (Nashville, Tennessee)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) Edward Sherwood (Nashville, Tennessee);  Antonio Hernandez (Franklin, Tennessee);  Julia Bohannon (Nashville, Tennessee)
ABSTRACT The present disclosure relates to phosphorylated hexaacyl disaccharide (PHAD) compounds, compositions, and methods for treating or preventing infections.
FILED Tuesday, May 01, 2018
APPL NO 16/610125
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7016 (20130101) Original (OR) Class
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389480 Oppenheim et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Joost J. Oppenheim (Bethesda, Maryland);  Dimiter S. Dimitrov (Pittsburgh, Pennsylvania);  De Yang (Frederick, Maryland);  Xin Chen (Frederick, Maryland);  Zhongyu Zhu (Frederick, Maryland)
ABSTRACT A human monoclonal antibody that specifically binds tumor necrosis factor receptor 2 (TNFR2), and a defucosylated form of the antibody, are described. The TNFR2-specific antibody was isolated from a human scFv phage display antibody library. The disclosed antibodies promote antibody-dependent cell-mediated cytotoxicity (ADCC) of human TNFR2+ CD4+ T regulatory cells in a dose- and time-dependent manner. Methods of using the TNFR2 antibodies, such as for tumor immunotherapy, are described.
FILED Tuesday, May 08, 2018
APPL NO 16/614652
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101) Original (OR) Class
A61K 47/6415 (20170801)
A61K 47/6929 (20170801)
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 16/2809 (20130101)
C07K 16/2878 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389483 Ji et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Duke University (Durham, North Carolina)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Ru-Rong Ji (Durham, North Carolina);  Gang Chen (Durham, North Carolina)
ABSTRACT Disclosed herein are bone marrow stromal cells. The bone marrow stromal cells may express and/or secrete TGF-βI. The bone marrow stromal cells may express CXCR4. Also disclosed herein is a method of treating pain in a subject in need thereof. The method of treating may include administration of the bone marrow stromal cells to the subject. The pain may be neuropathic pain.
FILED Friday, July 08, 2016
APPL NO 15/743208
ART UNIT 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 35/28 (20130101) Original (OR) Class
A61K 35/28 (20130101)
A61K 38/1841 (20130101)
A61K 38/1841 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 29/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389509 Filiano et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
ASSIGNEE(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S) Anthony J. Filiano (Charlottesville, Virginia);  Jonathan Kipnis (Charlottesville, Virginia)
ABSTRACT The present disclosure relates to methods of treating social dysfunction neurological disorders in an animal subject, comprising administering to the subject a therapeutically effective amount of a compound that increases STAT1 activity, and to a method of treating seizures in an animal subject, comprising administering to the subject a therapeutically effective amount of a compound that increases STAT1 activity. In some embodiments, the compound is IFN-γ.
FILED Wednesday, July 11, 2018
APPL NO 16/033160
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0014 (20130101)
A61K 9/0019 (20130101)
A61K 31/5513 (20130101)
A61K 38/17 (20130101)
A61K 38/217 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/08 (20180101)
A61P 25/28 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389517 Shea et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
ASSIGNEE(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S) Lonnie D. Shea (Evanston, Illinois);  Stephen D. Miller (Evanston, Illinois);  Jonathan Woon Teck Yap (Evanston, Illinois);  Daniel R. Getts (Northbrook, Illinois);  Derrick McCarthy (Evanston, Illinois)
ABSTRACT The present invention provides compositions comprising peptide-coupled biodegradable poly(lactide-co-glycolide) (PLG) particles. In particular, PLG particles are surface-functionalized to allow for coupling of peptide molecules to the surface of the particles (e.g., for use in eliciting induction of immunological tolerance).
FILED Wednesday, June 30, 2021
APPL NO 17/364351
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/19 (20130101)
A61K 9/1647 (20130101)
A61K 9/5153 (20130101)
A61K 39/00 (20130101)
A61K 39/0008 (20130101) Original (OR) Class
A61K 47/58 (20170801)
A61K 47/6911 (20170801)
A61K 47/6935 (20170801)
A61K 47/6937 (20170801)
A61K 2039/577 (20130101)
A61K 2039/622 (20130101)
A61K 2039/55555 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389521 Balint et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Etubics Corporation (Seatle, Washington)
ASSIGNEE(S) Etubics Corporation (Seattle, Washington)
INVENTOR(S) Joseph P. Balint (Seattle, Washington);  Frank R. Jones (Seattle, Washington);  Richard B. Gayle, III (Woodinville, Washington)
ABSTRACT Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided.
FILED Monday, April 27, 2020
APPL NO 16/859490
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/191 (20130101)
A61K 38/193 (20130101)
A61K 38/204 (20130101)
A61K 38/208 (20130101)
A61K 38/217 (20130101)
A61K 38/2013 (20130101)
A61K 38/2026 (20130101)
A61K 38/2033 (20130101)
A61K 38/2046 (20130101)
A61K 38/2066 (20130101)
A61K 39/00 (20130101)
A61K 39/0011 (20130101)
A61K 39/12 (20130101) Original (OR) Class
A61K 39/21 (20130101)
A61K 39/235 (20130101)
A61K 39/001106 (20180801)
A61K 39/001182 (20180801)
A61K 2039/54 (20130101)
A61K 2039/57 (20130101)
A61K 2039/545 (20130101)
A61K 2039/575 (20130101)
A61K 2039/5256 (20130101)
A61K 2039/55555 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/005 (20130101)
C07K 14/71 (20130101)
C07K 14/70503 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
C12N 2710/10034 (20130101)
C12N 2710/10321 (20130101)
C12N 2710/10334 (20130101)
C12N 2710/10343 (20130101)
C12N 2710/10371 (20130101)
C12N 2710/20034 (20130101)
C12N 2740/15034 (20130101)
C12N 2740/16234 (20130101)
C12N 2800/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389522 Galarza et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) TechnoVax, Inc. (Elmsford, New York)
ASSIGNEE(S) TECHNOVAX, INC. (Elmsford, New York)
INVENTOR(S) Jose M. Galarza (Elmsford, New York);  Helene Boigard (Elmsford, New York);  George Martin (Elmsford, New York)
ABSTRACT Flavivirus virus-like particles (VLPs) are provided that display on their surfaces antigenic flavivirus proteins. The VLPs include at least one flavivirus structural protein and at least one non-structural flavivirus protein. A DNA construct that includes sequences encoding flavivirus viral proteins used to assemble the flavivirus VLP is also provided. A method of producing flavivirus VLPs by introducing one or more the DNA constructs into a host cell is also provided. An immunogenic composition that includes the flavivirus VLP is also provided.
FILED Friday, September 04, 2020
APPL NO 17/013156
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101) Original (OR) Class
A61K 39/145 (20130101)
A61K 2039/5258 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 9/506 (20130101)
C12N 2770/24023 (20130101)
C12N 2770/24034 (20130101)
C12N 2770/24134 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389523 Kawaoka et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Centers of Excellence for Influenza Research and Surveillance (CEIRS)
APPLICANT(S) Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin)
INVENTOR(S) Yoshihiro Kawaoka (Middleton, Wisconsin);  Gabriele Neumann (Madison, Wisconsin);  Huihui Kong (Madison, Wisconsin)
ABSTRACT Methods of preparing influenza viruses having altered immunodominant epitopes in HA, e.g., having one or more residues in one or more of antigenic sites A-E in HA altered, and viral vectors, e.g., influenza virus VLPs or non-influenza viruses or VLPs thereof expressing or having influenza HAs with altered immunogenicity as a result of altered immunodominant epitopes therein are provided.
FILED Tuesday, August 20, 2019
APPL NO 16/545761
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/145 (20130101) Original (OR) Class
A61K 2039/521 (20130101)
A61K 2039/5258 (20130101)

Peptides
C07K 16/34 (20130101)
C07K 16/1018 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389526 Zeng et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Texas Tech University System (Lubbock, Texas)
ASSIGNEE(S) Texas Tech University System (Lubbock, Texas)
INVENTOR(S) Mingtao Zeng (El Paso, Texas);  Ke Wen (Harrison, New York)
ABSTRACT The present invention includes a live, self-attenuated therapeutic vaccine, virus and methods of making and using the same, comprising: an isolated virus comprising a viral genome that expresses one or more viral antigens; and an artificial microRNA 30 (amiR-30) expression cassette inserted into a viral neuraminidase (NA) or a viral non-structural (NS) gene segment that expresses an amiR-30 that specifically inhibits the expression of a host gene essential for influenza virus replication in host cells.
FILED Thursday, April 18, 2019
APPL NO 17/048714
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/39 (20130101)
A61K 39/145 (20130101) Original (OR) Class
A61K 2039/53 (20130101)
A61K 2039/5254 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/1131 (20130101)
C12N 2310/141 (20130101)
C12N 2760/16134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389529 Wussow et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) CITY OF HOPE (Duarte, California)
ASSIGNEE(S) CITY OF HOPE (Duarte, California)
INVENTOR(S) Felix Wussow (Monrovia, California);  Don J. Diamond (Glendora, California)
ABSTRACT An expression system for expressing a herpesvirus glycoprotein complex including a vector inserted with two or more nucleic acid sequences that encode two or more subunits of a herpesvirus glycoprotein complex linked by one or more linking sequences such that the subunits are co-expressed simultaneously and self-processed to assemble into a glycoprotein complex. The expression system or the vector can be included in a vaccine composition. The vaccine composition can be used for preventing or treating herpesvirus infections.
FILED Friday, July 13, 2018
APPL NO 16/630624
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/245 (20130101) Original (OR) Class

Peptides
C07K 14/05 (20130101)
C07K 14/045 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389530 Sampson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Duke University (Durham, North Carolina)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) John H Sampson (Durham, North Carolina);  Duane A Mitchell (Durham, North Carolina)
ABSTRACT The present invention relates to compositions, methods, and kits for eliciting an immune response to at least one CMV antigen expressed by a cancer cell, in particular for treating and preventing cancer. CMV determination methods, compositions, and kits also are provided.
FILED Wednesday, March 18, 2020
APPL NO 16/822354
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7105 (20130101)
A61K 39/12 (20130101)
A61K 39/39 (20130101)
A61K 39/245 (20130101) Original (OR) Class
A61K 45/06 (20130101)
A61K 2039/53 (20130101)
A61K 2039/5154 (20130101)
A61K 2039/5156 (20130101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2710/16122 (20130101)
C12N 2710/16134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389547 Kariko et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Katalin Kariko (Rydal, Pennsylvania);  Drew Weissman (Wynnewood, Pennsylvania)
ABSTRACT This invention provides RNA, oligoribonucleotide, and polyribonucleotide molecules comprising pseudouridine or a modified nucleoside, gene therapy vectors comprising same, methods of synthesizing same, and methods for gene replacement, gene therapy, gene transcription silencing, and the delivery of therapeutic proteins to tissue in vivo, comprising the molecules. The present invention also provides methods of reducing the immunogenicity of RNA, oligoribonucleotide, and polyribonucleotide molecules.
FILED Tuesday, March 12, 2019
APPL NO 16/299202
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/50 (20130101)
A61K 38/177 (20130101)
A61K 38/1816 (20130101)
A61K 48/00 (20130101)
A61K 48/005 (20130101)
A61K 48/0041 (20130101)
A61K 48/0066 (20130101) Original (OR) Class
A61K 48/0075 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/02 (20130101)

Peptides
C07K 14/47 (20130101)
C07K 14/505 (20130101)
C07K 14/4712 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/67 (20130101)
C12N 15/85 (20130101)
C12N 15/117 (20130101)
C12N 2310/17 (20130101)
C12N 2310/33 (20130101)
C12N 2310/3341 (20130101)
C12N 2800/95 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/68 (20130101)

Enzymes
C12Y 305/04004 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389552 Oeffinger et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Thomas Jefferson University (Philadelphia, Pennsylvania);  Drexel University (Philadelphia, Pennsylvania)
ASSIGNEE(S) Thomas Jefferson University (Philadelphia, Pennsylvania);  Drexel University (Philadelphia, Pennsylvania)
INVENTOR(S) Brian Edward Oeffinger (Philadelphia, Pennsylvania);  Margaret A. Wheatley (Media, Pennsylvania);  Rawan Shraim (Philadelphia, Pennsylvania);  Purva Vaidya (Flushing, New York);  John Robert Eisenbrey (Wayne, Pennsylvania)
ABSTRACT One aspect of the invention provides a method for freeze-drying surfactant-stabilized microbubbles. The method includes: preparing vials comprising a mixture comprising microbubbles; partially submerging the vials in a chilled water bath, wherein the water bath has a sub-freezing temperature; placing the vials on a cooled shelf of a lyophilizer; freeze-drying the vials in the lyophilizer; and capping the freeze-dried vials. Another aspect of the invention provides a method for annealing surfactant-stabilized microbubbles. The method includes: preparing vials comprising a mixture comprising microbubbles; passing the vials in and out of liquid nitrogen (LN2) until the mixture is frozen; holding the vials at −20° C.; placing the vials on a cooled shelf of a lyophilizer; freeze-drying the vials in the lyophilizer; and capping the freeze-dried vials.
FILED Friday, March 13, 2020
APPL NO 16/817898
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/223 (20130101) Original (OR) Class
A61K 49/227 (20130101)
A61K 2800/84 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389569 Badylak et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Stephen F. Badylak (West Lafayette, Indiana);  Hong Jiang (Export, Pennsylvania);  Hideyoshi Sato (Pittsburgh, Pennsylvania);  William R. Wagner (Gibsonia, Pennsylvania);  Yang Zhu (Pittsburgh, Pennsylvania)
ABSTRACT An injectable hydrogel composition that forms a porous gel rapidly after injection fro tissue engineering. The composition comprises a biodegradable, biocompatible, gelling polymer, that is optionally reverse-gelling; an Extra cellular matrix (ECM) material and a biocompatible porogen. Methods of making and using the composition are provided. A kit also is provided comprising the ingredients for making the hydrogel.
FILED Tuesday, April 03, 2018
APPL NO 16/496480
ART UNIT 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/26 (20130101)
A61L 27/48 (20130101)
A61L 27/52 (20130101)
A61L 27/56 (20130101) Original (OR) Class

Compositions of Macromolecular Compounds
C08L 33/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389668 Jin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Trustees of Indiana University (Indianapolis, Indiana)
ASSIGNEE(S) The Trustees of Indiana University (Indianapolis, Indiana)
INVENTOR(S) Jian-Yue Jin (Indianapolis, Indiana);  Feng-Ming Kong (Indianapolis, Indiana);  Hong Zhang (Wilmington, Delaware);  Huan Yao (Indianapolis, Indiana)
ABSTRACT Methods for calculating the radiation dose to the immune system of a patient undergoing radiotherapy are provided. In particular, the methods provide for calculating an effective dose to blood (EDIC) to circulating immune cells. The methods can be incorporated into radiotherapy (RT) treatment planning systems, which are also provided. The methods can be used to optimize patient treatment plans. Methods for treating a patient with RT with an optimized treatment plan are provided.
FILED Wednesday, May 02, 2018
APPL NO 16/968849
ART UNIT 2884 — Optics
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/1031 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389799 Burns et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Mark A. Burns (Ann Arbor, Michigan);  Alyse D. Krausz (Ann Arbor, Michigan);  Sarah Elizabeth Mena (Ann Arbor, Michigan);  Martin Patrick De Beer (Ann Arbor, Michigan);  Kevin R. Ward (Superior Township, Michigan);  Frederick Korley (Ann Arbor, Michigan)
ABSTRACT A microfluidic device system includes a channel having an entrance and an exit, a height at the entrance being greater than a height at the exit. The height of the channel may decrease continuously from the height at the entrance to the height at the exit. Cells or particles or beads traveling through the channel become trapped based on their size and/or deformability. A visual sensor captures images of the trapped cells or particles or beads, and image software analyzes the captured images to provide size and/or deformability and/or fluorescence information. A method of fabricating such a microfluidic device includes introducing a glass wafer to an etching solution at a specific rate such that a first end of the glass wafer is etched longer than other portions of the glass wafer.
FILED Friday, January 17, 2020
APPL NO 16/746408
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502707 (20130101)
B01L 3/502715 (20130101)
B01L 3/502761 (20130101) Original (OR) Class
B01L 2200/12 (20130101)
B01L 2200/0668 (20130101)
B01L 2300/0627 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/28 (20130101)
G01N 15/1475 (20130101)
G01N 21/6428 (20130101)
G01N 33/6803 (20130101)
G01N 33/54366 (20130101)
G01N 2015/1493 (20130101)
G01N 2021/6439 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390580 Del Poeta et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Maurizio Del Poeta (Mount Sinai, New York);  Visesato Mor (Nagaland, India)
ASSIGNEE(S) THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York)
INVENTOR(S) Maurizio Del Poeta (Mount Sinai, New York);  Visesato Mor (Nagaland, India)
ABSTRACT The present invention provides a compound having the structure:
FILED Monday, June 24, 2019
APPL NO 16/450772
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 37/28 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 31/16 (20130101)
A61K 31/16 (20130101)
A61K 31/166 (20130101)
A61K 31/4196 (20130101)
A61K 31/4196 (20130101)
A61K 31/7048 (20130101)
A61K 31/7048 (20130101)
A61K 31/7072 (20130101)
A61K 31/7072 (20130101)
A61K 38/12 (20130101)
A61K 38/12 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Acyclic or Carbocyclic Compounds
C07C 251/86 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390585 Stoltz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Brian M. Stoltz (San Marino, California);  Scott C. Virgil (Pasadena, California);  David E. White (Wayne, Pennsylvania);  Taiga Yurino (Kyoto, Japan);  Yiyang Liu (Pasadena, California);  Douglas C. Behenna (Laguna Niguel, California);  Douglas Duquette (Los Angeles, California);  Christian Eidamshaus (Pasadena, California)
ABSTRACT The invention provides heterocyclic compounds with quaternary centers and methods of preparing compounds. Methods include the method for the preparation of a compound of Formula (II):
comprising treating a compound of Formula (I):
with a transition metal catalyst and under alkylation conditions as valence and stability permit.
FILED Monday, February 01, 2021
APPL NO 17/164204
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 207/06 (20130101)
C07D 207/08 (20130101)
C07D 207/10 (20130101)
C07D 207/16 (20130101)
C07D 207/26 (20130101)
C07D 207/27 (20130101)
C07D 207/46 (20130101)
C07D 207/263 (20130101)
C07D 207/267 (20130101)
C07D 207/273 (20130101)
C07D 207/277 (20130101)
C07D 211/16 (20130101)
C07D 211/18 (20130101)
C07D 211/22 (20130101)
C07D 211/34 (20130101)
C07D 211/38 (20130101)
C07D 211/60 (20130101)
C07D 211/76 (20130101)
C07D 211/78 (20130101) Original (OR) Class
C07D 211/88 (20130101)
C07D 211/90 (20130101)
C07D 211/94 (20130101)
C07D 211/96 (20130101)
C07D 223/04 (20130101)
C07D 223/10 (20130101)
C07D 241/04 (20130101)
C07D 241/08 (20130101)
C07D 241/52 (20130101)
C07D 265/30 (20130101)
C07D 265/32 (20130101)
C07D 309/04 (20130101)
C07D 309/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390613 Hadden
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) UNIVERSITY OF CONNECTICUT (Farmington, Connecticut)
ASSIGNEE(S) UNIVERSITY OF CONNECTICUT (Farmington, Connecticut)
INVENTOR(S) Matthew Kyle Hadden (Ellington, Connecticut)
ABSTRACT Disclosed herein are analogues of itraconazole that are both angiogenesis and hedgehog signaling pathway inhibitors, formulations thereof, including liposome formulations thereof. The compounds are expected to be useful in the treatment of cell proliferation disorders such as cancer, particularly cancers that are dependent upon the hedgehog signaling pathway such as basal cell carcinoma and medulloblastoma.
FILED Monday, August 20, 2018
APPL NO 16/639242
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/38 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Heterocyclic Compounds
C07D 405/12 (20130101)
C07D 405/14 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390626 Garland et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Tosk, Inc. (Mountain View, California)
ASSIGNEE(S) Tosk, Inc. (Mountain View, California)
INVENTOR(S) William A. Garland (Mountain View, California);  Solomon B. Ungashe (Mountain View, California);  Stephen D. Yanofsky (Mountain View, California);  Philip Liaw (Mountain View, California);  Annie L. Lennek (Mountain View, California)
ABSTRACT Pyrazolopyrimidine RAS modulating compounds and methods of using the same are provided. The pyrazolopyrimidine compounds find use in modulating the activity of a target RAS in a sample. The target RAS can be a mutant RAS that is implicated in a disease of interest. In some cases, the subject compounds can inhibit the growth of cancer cells whose progression is driven by kRAS or a mutated kRAS. Methods of treating a subject for a RAS driven disease including administering a therapeutically effective amount of the subject compound are provided. Also provided are pharmaceutical compositions and kits which include the subject compounds.
FILED Tuesday, January 28, 2020
APPL NO 16/774381
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Heterocyclic Compounds
C07D 487/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390629 Vlaar et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
National Institute on Minority Health and Health Disparities (NIMHD)
APPLICANT(S) UNIVERSITY OF PUERTO RICO (San Juan, Puerto Rico)
ASSIGNEE(S) UNIVERSITY OF PUERTO RICO (San Juan, Puerto Rico)
INVENTOR(S) Cornelis P. Vlaar (San Juan, Puerto Rico);  Suranganie Dharmawardhane Flanagan (San Juan, Puerto Rico);  Eliud Hernandez-O'Farrill (San Juan, Puerto Rico);  Linette Castillo-Pichardo (San Juan, Puerto Rico)
ABSTRACT Compounds are disclosed that inhibit RhoGTPases that are useful for inhibiting hyperproliferative and neoplastic diseases. Specifically, the compounds inhibit the GTPases Rac and Cdc42 that are overactive or overexpressed in signaling pathways in cancer and metastasis. Methods for treatment of cancer and hyperproliferative diseases are disclosed.
FILED Thursday, April 01, 2021
APPL NO 17/220319
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 401/14 (20130101)
C07D 403/04 (20130101)
C07D 403/14 (20130101)
C07D 409/14 (20130101)
C07D 491/048 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390630 Ghosh et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Arun K. Ghosh (West Lafayette, Indiana);  Hiroaki Mitsuya (Kumamoto, Japan);  Prasanth Reddy Nyalapatla (Henrico, Virginia)
ABSTRACT Various embodiments relate to a compound of the formula (I) and (II), wherein X, X1, X2, X3, and R1-R4 are defined herein, as well as pharmaceutical compositions comprising compounds of the formula (I) and/or (II) and methods of treating an HIV infection comprising administering a therapeutically effective amount of one or more compounds of formula (I) and/or (II), or a pharmaceutical composition comprising compounds of the formula (I) and/or (II), to a patient in need thereof.
FILED Tuesday, May 04, 2021
APPL NO 17/307905
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 311/78 (20130101)
C07D 493/06 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390640 Blagg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) UNIVERSITY OF KANSAS (Lawrence, Kansas)
ASSIGNEE(S) UNIVERSITY OF KANSAS (Lawrence, Kansas)
INVENTOR(S) Brian S. J. Blagg (Lawrence, Kansas);  Bhaskar Reddy Kusuma (Lake Ronkonkoma, New York);  Teather Sundstrom (Eckelson, North Dakota)
ABSTRACT Hsp90 C-terminal inhibitors and pharmaceutical compositions containing such compounds are provided. The compounds of the disclosure are useful for the treatment and/or prevention of neurodegenerative disorders such as diabetic peripheral neuropathy.
FILED Friday, December 04, 2020
APPL NO 17/112060
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 211/17 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 15/203 (20130101)
C07H 15/207 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390644 Dai et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Mingji Dai (West Lafayette, Indiana);  Ji-Xin Cheng (Newton, Massachusetts)
ABSTRACT A method of forming a probe, wherein the method includes converting cholenic acid into a compound with a terminal alkyne group, wherein the converting the cholenic acid comprises using a sequence, wherein the sequence comprises synthesizing a THP-protection group, LiAlH4 reduction, Dess-Martin oxidation, and Seyferth-Gilbert-Bestmann homologation. The method additionally includes forming A-Chol by removing the THP-protection. Further, the method includes forming PhA-Chol from the compound with the terminal alkyne group via a palladiumcatalyzed Sonogashira reaction. Additionally, the method includes forming PhDY Chol from the compound with the terminal alkyne group via a coppercatalyzed Cadiot-Chodkiewicz reaction.
FILED Tuesday, November 20, 2018
APPL NO 16/197250
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Steroids
C07J 9/00 (20130101) Original (OR) Class
C07J 9/005 (20130101)
C07J 17/00 (20130101)
C07J 41/0094 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390646 Eisenberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) David S. Eisenberg (Los Angeles, California);  Smriti Sangwan (Los Angeles, California);  Lin Jiang (Santa Monica, California)
ABSTRACT This invention relates to inhibitory peptides which bind to α-synuclein molecules and inhibit α-synuclein amyloidogenic aggregation, α-synuclein cytotoxicity, and spread of α-synuclein. Methods of making and using the inhibitory peptides (e.g. to treat subjects having conditions or diseases that are mediated by α-synuclein, such as Parkinson's disease, dementia with Lewy bodies, or MSA) are described.
FILED Tuesday, May 26, 2020
APPL NO 16/883515
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/16 (20180101)

Peptides
C07K 7/02 (20130101) Original (OR) Class
C07K 7/08 (20130101)
C07K 14/47 (20130101)
C07K 14/4711 (20130101)
C07K 2319/10 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6896 (20130101)
G01N 2800/2835 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390649 Kawaoka et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Centers of Excellence for Influenza Research and Surveillance (CEIRS)
APPLICANT(S) Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin)
INVENTOR(S) Yoshihiro Kawaoka (Middleton, Wisconsin);  Gabriele Neumann (Madison, Wisconsin);  Jihui Ping (Nanjing, China PRC)
ABSTRACT An isolated recombinant influenza virus is provided having PA, PB1, PB2, NP, NS, M, NA and HA viral segments, wherein the PB1 viral segment encodes a PB1 with a residue other than isoleucine at position 711 or the M viral segment encodes a M1 with a residue other than methionine at position 128, wherein the recombinant influenza virus has enhanced replication relative to a corresponding influenza virus having a PB1 viral segment that encodes a PB1 with an isoleucine at position 711 or having a M viral segment that encodes a M1 with methionine at position 128, as well as methods of making and using the virus.
FILED Friday, May 01, 2020
APPL NO 16/865194
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/007 (20130101)
A61K 9/0019 (20130101)
A61K 39/145 (20130101)
A61K 2039/54 (20130101)
A61K 2039/544 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/16 (20180101)

Peptides
C07K 14/005 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2760/16121 (20130101)
C12N 2760/16122 (20130101)
C12N 2760/16134 (20130101)
C12N 2760/16152 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390650 Yao
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts)
ASSIGNEE(S) THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts)
INVENTOR(S) Feng Yao (Southborough, Massachusetts)
ABSTRACT The present invention is directed to Herpes simplex-2 viruses that may be used in vaccines to immunize patients against genital herpes.
FILED Friday, February 01, 2019
APPL NO 16/967275
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/245 (20130101)
A61K 2039/5254 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/22 (20180101)

Peptides
C07K 14/005 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2710/16621 (20130101)
C12N 2710/16622 (20130101)
C12N 2710/16634 (20130101)
C12N 2710/16662 (20130101)
C12N 2710/16671 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390651 Lenouen et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland);  CODAGENIX, INC. (Farmingdale, New York)
ASSIGNEE(S) The USA, Secretary, DHHS (Bethesda, Maryland);  Codagenix, Inc. (Stony Brook, New York)
INVENTOR(S) Cyril Lenouen (Bethesda, Maryland);  Ursula J. Buchholz (Silver Spring, Maryland);  Peter L. Collins (Silver Spring, Maryland);  Steffen Mueller (Stony Brook, New York)
ABSTRACT Reported herein are presumptively de-attenuating mutations that are useful, either individually or in combinations that may include other known mutations, in producing recombinant strains of human respiratory syncytial virus (RSV) exhibiting attenuation phenotypes. Also described herein is a novel RSV construct, Min_L-NPM2-1(N88K)L, which exhibits an attenuated phenotype, is stable and is as immunogenic as wild type RSV. The recombinant RSV strains described here are suitable for use as live-attenuated RSV vaccines. Exemplary vaccine candidates are described. Also provided are polynucleotide sequences capable of encoding the described viruses, as well as methods for producing and using the viruses.
FILED Monday, August 31, 2020
APPL NO 17/008025
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/0043 (20130101)
A61K 39/155 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/20 (20180101)

Peptides
C07K 14/08 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/04 (20130101)
C12N 2760/00021 (20130101)
C12N 2760/00034 (20130101)
C12N 2760/00062 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390662 Raines et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S) Ronald T. Raines (Cambridge, Massachusetts);  Matthew D. Shoulders (Cambridge, Massachusetts);  Jonathan A. Hodges (Durham, North Carolina)
ABSTRACT Novel collagen mimics are disclosed with a tripeptide unit having the formula (Xaa-Yaa-Gly)n, where one of the positions Xaa or Yaa is a bulky, non-electron withdrawing proline derivative. By substituting a proline derivative at either the Xaa or Yaa position in the native collagen helix, the stability of the helix is increased due solely to steric effects relative to prior known collagen-related triple helices. Methods are also disclosed for making the novel collagen mimics.
FILED Friday, June 21, 2019
APPL NO 16/448750
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 5/0821 (20130101)
C07K 14/001 (20130101)
C07K 14/78 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390665 Smider et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Scripps Research Institute (La Jolla, California)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Vaughn Smider (San Diego, California);  Omar A. Bazirgan (San Diego, California);  Hongyuan Helen Mao (San Diego, California);  Peter Schultz (La Jolla, California);  Feng Wang (Beijing, China PRC);  Yong Zhang (Los Angeles, California)
ABSTRACT Disclosed herein are immunoglobulin constructs comprising at least one immunoglobulin domain or fragment thereof; and a therapeutic polypeptide or derivative or variant thereof attached to or inserted into said immunoglobulin domain. Also provided are immunoglobulin constructs comprising a mammalian immunoglobulin heavy chain comprising at least a portion of a knob domain in the complementarity-determining region 3 (CDR3H) or fragment thereof; and a therapeutic polypeptide attached to or inserted into said knob domain of the CDR3H. Also provided are immunoglobulin constructs comprising a mammalian immunoglobulin heavy chain comprising at least a portion of a stalk domain in the complementarity-determining region 3 (CDR3H) or fragment thereof; and a therapeutic polypeptide attached to or inserted into said stalk domain of the CDR3H. Also described herein are methods and compositions comprising the immunoglobulin constructs described herein for treatment and prevention of a disease or condition in a subject.
FILED Tuesday, January 14, 2020
APPL NO 16/742759
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/53 (20130101)
C07K 16/00 (20130101)
C07K 16/10 (20130101) Original (OR) Class
C07K 16/46 (20130101)
C07K 2317/20 (20130101)
C07K 2317/50 (20130101)
C07K 2317/55 (20130101)
C07K 2317/73 (20130101)
C07K 2317/76 (20130101)
C07K 2317/94 (20130101)
C07K 2317/565 (20130101)
C07K 2317/569 (20130101)
C07K 2318/00 (20130101)
C07K 2319/00 (20130101)
C07K 2319/30 (20130101)
C07K 2319/50 (20130101)
C07K 2319/55 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/00 (20130101)
C12N 15/09 (20130101)
C12N 15/62 (20130101)
C12N 15/63 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390667 Bennett et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado);  The Regents of the University of California (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California);  THE REGENTS OF THE UNIVERSITY OF COLORAD (Denver, Colorado)
INVENTOR(S) Jeffery L. Bennett (Aurora, Colorado);  Gregory P. Owens (Aurora, Colorado);  Alan S. Verkman (San Francisco, California)
ABSTRACT The present invention is directed to antibodies binding to aquaporin 4 (AQP4) and methods of using such antibodies to treat neuromyelitis optica (NMO) either as a monotherapy or in combination with standard NMO therapies such as immunosuppressives or plasmaphersis.
FILED Monday, May 18, 2020
APPL NO 16/877103
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/3955 (20130101)
A61K 45/06 (20130101)

Peptides
C07K 16/18 (20130101) Original (OR) Class
C07K 16/28 (20130101)
C07K 2317/21 (20130101)
C07K 2317/71 (20130101)
C07K 2317/76 (20130101)
C07K 2317/92 (20130101)
C07K 2317/732 (20130101)
C07K 2317/734 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390683 Pastan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Ira H. Pastan (Chevy Chase, Maryland);  Masanori Onda (Germantown, Maryland);  Tapan Bera (Frederick, Maryland);  Mitchell Ho (Urbana, Maryland)
ABSTRACT Polypeptides and proteins that specifically bind to and immunologically recognize human mesothelin582-598 (IP-NGYLVLDLSMQEALS) (SEQ ID NO: 1) are disclosed. Anti-mesothelin binding moieties, nucleic acids, recombinant expression vectors, host cells, populations of cells, pharmaceutical compositions, and conjugates relating to the polypeptides and proteins are disclosed. Methods of reducing mesothelin shed from cell membranes, methods of reducing the activity of TNFα converting enzyme, methods of detecting the presence of cancer, and methods of treating or preventing cancer are also disclosed.
FILED Thursday, May 17, 2018
APPL NO 16/613971
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/395 (20130101)
A61K 47/6829 (20170801)
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 16/30 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/63 (20130101)
C12N 2800/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/574 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390684 Mollick et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Joseph A. Mollick (Palo Alto, California);  Pearline Teo (Singapore, Singapore);  Paul J. Utz (Stanford, California)
ABSTRACT The present invention provides novel IgE antibodies useful for inhibiting or preventing metastatic cancer. Also provided are methods to inhibit tumor metastasis by modulating the activity of at least one non-tumor cell, treating a patient to inhibit or prevent tumor metastases of a primary solid tumor, treating metastatic carcinoma, reducing metastasis of carcinoma cells, and reducing the growth kinetics of a primary solid tumor or a metastasized cell or tumor.
FILED Monday, October 14, 2019
APPL NO 16/600762
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/505 (20130101)

Peptides
C07K 16/2887 (20130101)
C07K 16/3092 (20130101) Original (OR) Class
C07K 2317/24 (20130101)
C07K 2317/52 (20130101)
C07K 2317/56 (20130101)
C07K 2317/70 (20130101)
C07K 2317/73 (20130101)
C07K 2317/76 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390721 Alexanian et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S) Erik Alexanian (Chapel Hill, North Carolina);  Frank Albert Leibfarth (Carrboro, North Carolina);  Jill Williamson (Chapel Hill, North Carolina);  Will Czaplyski (Cambridge, Massachusetts)
ABSTRACT The subject matter described herein relates to methods for polymer xanthylation and the xanthylated polymers produced by such methods. Subsequent replacement of the xanthylate moiety allows facile entry into functionalized polymers.
FILED Wednesday, October 03, 2018
APPL NO 16/753390
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 10/02 (20130101)
C08F 10/06 (20130101)
C08F 10/10 (20130101)
C08F 2810/00 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 63/912 (20130101)
C08G 64/42 (20130101)
C08G 65/3348 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 7/12 (20130101) Original (OR) Class
C08J 2323/26 (20130101)
C08J 2323/36 (20130101)
C08J 2367/04 (20130101)
C08J 2369/00 (20130101)
C08J 2371/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390848 Blazar et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota);  Regents of the University of Michigan (Ann Arbor, Michigan);  The Ohio State University (Columbus, Ohio)
INVENTOR(S) Bruce R. Blazar (Golden Valley, Minnesota);  Keli Hippen (Minneapolis, Minnesota);  Pavan Reddy (Ann Arbor, Michigan);  Yaping Sun (Ann Arbor, Michigan);  Ramiro Garzon (Columbus, Ohio)
ABSTRACT This disclosure provides miRNA/mRNA pairs that can be used to increase the efficacy of T cells or to down-modulate T cell efficacy and restore equilibrium.
FILED Wednesday, June 28, 2017
APPL NO 16/314141
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 37/06 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0636 (20130101) Original (OR) Class
C12N 5/0637 (20130101)
C12N 15/113 (20130101)
C12N 2310/113 (20130101)
C12N 2320/32 (20130101)
C12N 2501/65 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390852 Ghaedi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Yale University (New Haven, Connecticut)
ASSIGNEE(S) Yale University (New Haven, Connecticut)
INVENTOR(S) Mahboobe Ghaedi (New Haven, Connecticut);  Laura Niklason (Greenwich, Connecticut)
ABSTRACT The present invention provides compositions and methods of preparing airway cells. In one aspect, an epithelial airway cell derived from an induced pluripotent stem (iPS) cell characterized by expression of airway cell surface markers and an ability to proliferate is described. In another aspect, methods of differentiating an iPS into an epithelial airway cell is provided. Engineered lungs, methods of making such engineered lungs comprising the epithelial airway cells and treating respiratory disorders are also disclosed.
FILED Wednesday, January 14, 2015
APPL NO 15/100978
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/36 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0688 (20130101) Original (OR) Class
C12N 5/0689 (20130101)
C12N 2500/99 (20130101)
C12N 2501/15 (20130101)
C12N 2501/115 (20130101)
C12N 2501/155 (20130101)
C12N 2501/415 (20130101)
C12N 2506/45 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390853 Pokorski et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) Jonathan Pokorski (San Diego, California);  Nicole Steinmetz (San Diego, California);  Parker Lee (Los Angeles, California)
ABSTRACT A method of producing plant virus-like particles includes freeze drying an aqueous solution of plant virus particles to produce a substantially RNA-free plant virus-like particles.
FILED Monday, April 27, 2020
APPL NO 16/859400
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101) Original (OR) Class
C12N 2770/18023 (20130101)
C12N 2770/18051 (20130101)
C12N 2770/32023 (20130101)
C12N 2770/32051 (20130101)

Enzymes
C12Y 301/27005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390861 Friedland et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) EDITAS MEDICINE, INC. (Cambridge, Massachusetts);  DUKE UNIVERSITY (Durham, North Carolina)
ASSIGNEE(S) EDITAS MEDICINE, INC. (Cambridge, Massachusetts);  DUKE UNIVERSITY (Durham, North Carolina)
INVENTOR(S) Ari E. Friedland (Boston, Massachusetts);  Penrose O'Donnell (Yarmouth, Massachusetts);  David A. Bumcrot (Belmont, Massachusetts);  Bryan R. Cullen (Durham, North Carolina)
ABSTRACT Genome editing systems and genetic constructs that target a herpes simplex virus (HSV) viral gene, where the systems comprise one Cas9 molecule, and a gRNA molecule, compositions and cells comprising such genome editing systems and genetic constructs as well as methods for using the genome editing systems, genetic constructs, compositions and cells for genome engineering, and for preventing, treating or reducing HSV infection.
FILED Friday, April 26, 2019
APPL NO 16/395833
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101) Original (OR) Class
C12N 15/11 (20130101)
C12N 15/1133 (20130101)
C12N 2310/20 (20170501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390882 Stankey et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Complementary and Integrative Health (NCCIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) VARIGEN BIOSCIENCES CORPORATION (Middleton, Wisconsin)
ASSIGNEE(S) VARIGEN BIOSCIENCES CORPORATION (Middleton, Wisconsin)
INVENTOR(S) Robert Joseph Stankey (Madison, Wisconsin);  David Mead (Middleton, Wisconsin)
ABSTRACT Disclosed herein are recombinant methods of activating expression of one or more biosynthetic gene clusters comprising more than one gene, the method comprising a recombinant DNA expression vector that possess two opposable inducible promoters that drives expression of a biosynthetic gene cluster exogenously from outside of the cluster to produce polyketides or non-ribosomal peptides in a heterologous host.
FILED Wednesday, March 11, 2020
APPL NO 16/815399
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/52 (20130101)
C12N 15/70 (20130101)
C12N 15/86 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390883 Gao et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Guangping Gao (Westborough, Massachusetts);  James M. Wilson (Philadelphia, Pennsylvania);  Mauricio R. Alvira (Philadelphia, Pennsylvania)
ABSTRACT Sequences of a serotype 8 adeno-associated virus and vectors and host cells containing these sequences are provided. Also described are methods of using such host cells and vectors in production of rAAV particles.
FILED Friday, October 01, 2021
APPL NO 17/492229
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 35/761 (20130101)
A61K 38/45 (20130101)
A61K 38/177 (20130101)
A61K 38/4846 (20130101)
A61K 48/00 (20130101)

Peptides
C07K 14/005 (20130101)
C07K 14/705 (20130101)
C07K 14/755 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 9/644 (20130101)
C12N 9/1018 (20130101)
C12N 15/86 (20130101) Original (OR) Class
C12N 15/8645 (20130101)
C12N 2750/14122 (20130101)
C12N 2750/14143 (20130101)
C12N 2750/14152 (20130101)
C12N 2830/008 (20130101)
C12N 2830/48 (20130101)
C12N 2830/85 (20130101)

Enzymes
C12Y 201/03003 (20130101)
C12Y 304/21021 (20130101)
C12Y 304/21022 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390885 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts)
ASSIGNEE(S) CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts)
INVENTOR(S) Yi Zhang (Newton, Massachusetts);  Shogo Matoba (Brookline, Massachusetts)
ABSTRACT The present invention provides methods and compostions to improve the efficiency of somatic cell nuclear transfer (SCNT) and the consequent production of nuclear transfer ESC (ntESC) and transgenic cells and/or non-human animals. More specifically, the present invention relates to the discovery that trimethylation of Histone H3-Lysine 9 (H3K9me3) in reprogramming resistant regions (RRRs) in the nuclear genetic material of donor somatic cells prevents efficient somatic cell nuclear reprogramming or SCNT. The present invention provide methods and compositions to decrease H3K9me3 in methods to improve efficacy of SCNT by exogenous or overexpression of the demethylase Kdm4 family and/or inhibiting methylation of H3K9me3 by inhibiting the histone methyltransferases Suv39h1 and/or Suv39h2.
FILED Tuesday, September 15, 2015
APPL NO 15/511348
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0273 (20130101)
A01K 2227/105 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0604 (20130101)
C12N 5/0606 (20130101)
C12N 15/877 (20130101) Original (OR) Class
C12N 15/1137 (20130101)
C12N 2310/14 (20130101)
C12N 2517/04 (20130101)

Enzymes
C12Y 201/01043 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390908 Pederson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts);  University of Central Florida Research Foundation, Inc. (Orlando, Florida)
ASSIGNEE(S) UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts);  UNIVERSITY OF CENTRAL FLORIDA FOUNDATION, INC. (Orlando, Florida)
INVENTOR(S) Thoru Pederson (Worcester, Massachusetts);  Hanhui Ma (Shrewsbury, Massachusetts);  Li-Chun Tu (Worcester, Massachusetts);  Ardalan Naseri (Orlando, Florida);  Maximilaan Huisman (Worcester, Massachusetts);  Shaojie Zhang (Orlando, Florida)
ABSTRACT A C9orf72 DNA repeat expansion can be detected using a CRISPR Arrayed Repeat Detection System (CARDS). Based upon the compositions and methods supporting this platform primary cell cultures and/or blood cell smears can be tested under conventional clinical diagnostic laboratory conditions to diagnose genetically-based diseases having DNA repeat expansions, including but not limited to ALS. dCas9 constructs are also contemplated as having fluorescent proteins bound to any or all stem loop sequences, wherein detection of a plurality of dCas9 constructs having different colored fluorescent proteins can simultaneously detect at least six (6) different gene target loci.
FILED Thursday, September 01, 2016
APPL NO 15/757240
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/02 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/11 (20130101)
C12N 15/85 (20130101)
C12N 2310/20 (20170501)
C12N 2310/3519 (20130101)
C12N 2830/003 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6816 (20130101) Original (OR) Class
C12Q 1/6816 (20130101)
C12Q 2521/507 (20130101)
C12Q 2563/107 (20130101)
C12Q 2563/119 (20130101)
C12Q 2600/156 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390918 Quake et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
NIH Office of the Director (NIHOD)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Stephen R. Quake (Stanford, California);  Thomas M. Snyder (Palo Alto, California);  Hannah Valantine (Stanford, California)
ABSTRACT The invention provides methods, devices, compositions and kits for diagnosing or predicting transplant status or outcome in a subject who has received a transplant.
FILED Tuesday, May 18, 2021
APPL NO 17/323917
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101) Original (OR) Class
C12Q 1/6837 (20130101)
C12Q 1/6869 (20130101)
C12Q 1/6883 (20130101)
C12Q 2600/106 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 20/00 (20190201)
G16B 20/20 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390923 Chinnaiyan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Arul Chinnaiyan (Plymouth, Michigan);  John Prensner (Ann Arbor, Michigan);  Matthew Iyer (Ann Arbor, Michigan)
ABSTRACT The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to ncRNAs as diagnostic markers and clinical targets for prostate, lung, breast and pancreatic cancer.
FILED Wednesday, June 26, 2019
APPL NO 16/453195
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/11 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/16 (20130101)
C12Q 2600/118 (20130101)
C12Q 2600/158 (20130101)
C12Q 2600/178 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11391268 Han et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S) Jooli Han (Pittsburgh, Pennsylvania);  Dennis Robert Trumble (Pittsburgh, Pennsylvania)
ABSTRACT A muscle-powered pulsation device for cardiac support including a muscle energy converter device including a piston arrangement for directing fluid out of an outlet of the muscle energy converter device using energy provided by a patient's muscle, and a hydraulic volume amplification device fluidly connected to the muscle energy converter device. The volume amplification device includes a casing including an inlet and an outlet, the inlet in fluid communication with the outlet of the muscle energy converter device, at least one resilient member positioned within an interior cavity defined by the casing, and at least one piston member movably and sealingly positioned within the interior cavity of the casing and operatively connected to the at least one resilient member, the at least one piston member separating the interior cavity into a first chamber and a second chamber.
FILED Tuesday, June 19, 2018
APPL NO 16/617706
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 60/40 (20210101)
A61M 60/148 (20210101)
A61M 60/268 (20210101)

Positive-displacement Machines for Liquids; Pumps
F04B 9/107 (20130101) Original (OR) Class
F04B 43/067 (20130101)
F04B 45/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11391726 Lake et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona);  MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (Rochester, Minnesota)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona);  MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (Rochester, Minnesota)
INVENTOR(S) Douglas Lake (Scottsdale, Arizona);  Thai H. Ho (Scottsdale, Arizona);  Glen J. Weiss (Phoenix, Arizona)
ABSTRACT The present invention includes a method for screening one or more agents that modulate Regulatory T cell (Treg) activity, the method comprising the steps of: incubating a population CD4+ cells isolated from human blood peripheral mononuclear cells the CD4+ cells in contact with MoT cells in the presence of the one or more agents suspected of modulating Treg activity; detecting activation of the CD4+ cells without or with the agent; and comparing the activation of the CD4+ cells without or with the agent, wherein a change in activation following incubation with the agent relative to the activation of the PBMCs following incubation without the agent indicates that the agent is a modulator of Treg activity.
FILED Wednesday, September 25, 2019
APPL NO 17/256592
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0637 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/505 (20130101) Original (OR) Class
G01N 2500/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11391729 Bergo
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) Adeptrix Corp. (Beverly, Massachusetts)
ASSIGNEE(S) ADEPTRIX CORP. (Beverly, Massachusetts)
INVENTOR(S) Vladislav B. Bergo (Boston, Massachusetts)
ABSTRACT Bead arrays suitable for analysis by mass spectrometry are disclosed. In an embodiment, a bead array includes multiple reactive sites, each of the reactive sites being capable of binding multiple distinct target analytes.
FILED Friday, September 07, 2018
APPL NO 16/125164
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/745 (20130101)
G01N 33/6845 (20130101)
G01N 33/6848 (20130101)
G01N 33/6854 (20130101)
G01N 33/54306 (20130101) Original (OR) Class
G01N 33/54313 (20130101)
G01N 2440/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11391739 Carrasco et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts)
ASSIGNEE(S) DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts)
INVENTOR(S) Ruben Carrasco (Brookline, Massachusetts);  Di Zhu (Newton, Massachusetts)
ABSTRACT Provided by the invention are methods for identifying therapeutic agents for treating multiple myeloma or another hematological malignancy, as well as methods for determining the prognosis of a patient with multiple myeloma or another hematological malignancy. The methods are based in part on the inventors' discovery that an extracellular form of cyclophilin A binds to CD147 expressed on multiple myeloma cells.
FILED Friday, June 14, 2019
APPL NO 16/441166
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101)
C12Q 2600/118 (20130101)
C12Q 2600/136 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57407 (20130101) Original (OR) Class
G01N 2333/99 (20130101)
G01N 2333/70596 (20130101)
G01N 2500/02 (20130101)
G01N 2800/52 (20130101)
G01N 2800/56 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11391740 Huang
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S) Haojie Huang (Rochester, Minnesota)
ABSTRACT This document provides methods and materials involved in identifying and/or treating mammals having a treatment-resistant prostate cancer (e.g., an enzalutamide-resistant, castration-resistant prostate cancer). For example, methods and materials for identifying a mammal (e.g., a human) having treatment-resistant prostate cancer (e.g., an enzalutamide-resistant, castration-resistant prostate cancer) as having an elevated level of one or more polypeptides (e.g., one or more of a CXXC5, a CXXC4, a TET2, an ID1, an ID3, and/or a PFN2 polypeptide) in treatment-resistant prostate tissue are provided. Methods and materials for administering one or more targeted therapies with or without one or more chemotherapeutic agents to a mammal having treatment-resistant prostate cancer identified as having an elevated level of one or more polypeptides (e.g., one or more of a CXXC5, a CXXC4, a TET2, an ID1, an ID3, and/or a PFN2 polypeptide) in treatment-resistant prostate tissue also are provided.
FILED Tuesday, May 19, 2020
APPL NO 16/878244
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/551 (20130101)
A61K 45/06 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57434 (20130101) Original (OR) Class
G01N 2333/4703 (20130101)
G01N 2333/90245 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11391803 Bilgic et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Berkin Bilgic (Boston, Massachusetts);  Sohyun Han (Cambridge, Massachusetts);  Stephen F. Cauley (Cambridge, Massachusetts);  Lawrence L. Wald (Cambridge, Massachusetts);  Kawin Setsompop (Charleston, Massachusetts)
ABSTRACT Systems and methods are provided for improving MRI data acquisition efficiency while providing more detailed information with high resolution and isotropic resolution without gaps. Improved data acquisition efficiency may be achieved by implementing a machine learning algorithm with a hardware processor and a memory to estimate imperfections in fast imaging sequences, such as a multi-shot echo planar imaging (MS-EPI) sequence. These imperfections, such as patient motion, physiological noise, and phase variations, may be difficult to model or otherwise estimate using standard physics-based reconstructions.
FILED Monday, March 04, 2019
APPL NO 16/976997
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/5608 (20130101)
G01R 33/5616 (20130101)
G01R 33/56509 (20130101) Original (OR) Class

Computer Systems Based on Specific Computational Models
G06N 3/04 (20130101)

Image Data Processing or Generation, in General
G06T 11/008 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11392016 Grunwald et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
Non-Profit Organization (NPO)
Worcester Foundation for Biomedical Research (WFBR)
Worcester Foundation for Experimental Biology (WFEB)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) David Grunwald (Worcester, Massachusetts);  Maximiliaan Huisman (Brookfield, Massachusetts);  Carlas Smith (Delft, Netherlands)
ABSTRACT The described embodiments are directed to a system and methods of calibrating a fluorescence microscope and/or light detection device using a calibrating apparatus. The apparatus may comprise a main body housing, a sensor head, and a microcontroller assembly disposed within the housing. The housing may include an adapter to mechanically couple the housing to a microscope. The sensor head may comprise (i) an optical power sensor to produce a power signal representative of an optical power magnitude of light applied to the optical power sensor, (ii) an optical wavelength sensor configured to produce wavelength information associated with the light applied to the optical wavelength sensor, and (iii) a light source configured to direct light toward a detection device associated with the microscope. The microcontroller assembly may be configured to generate an optical power magnitude value based on the power signal and adjusted according to the wavelength information.
FILED Tuesday, October 13, 2020
APPL NO 17/069335
ART UNIT 2878 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 21/008 (20130101)
G02B 21/0032 (20130101)
G02B 21/361 (20130101)
G02B 21/362 (20130101)

Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor
G03B 21/204 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11393087 Parikh et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Children's Hospital Medical Center (Cincinnati, Ohio)
ASSIGNEE(S) Children's Hospital Medical Center (Cincinnati, Ohio)
INVENTOR(S) Nehal Parikh (Cincinnati, Ohio);  Lili He (Cincinnati, Ohio)
ABSTRACT A system for objectively analyzing medical image data for the presence of diffuse white matter abnormalities (DWMA) is configured to identify and determine DWMA characteristics that are not visually apparent. As compared to subjective visual diagnosis, objectively determined DWMA characteristics may be automatically compared to each other, and may be compared to and associated with various scales, evaluations, or other assessment criteria used to measure aspects of infant development. As a result, the disclosed system may objectively determine an impact that objectively determined DWMA characteristics will have on one or more developmental scales, which can be expressed as a time deficit, score deficit, or other value indicative of development deficits. The system may be integrated with medical imaging devices to provide near-immediate objective analysis for developmental impact at the point of care and in parallel with conventional imaging tasks, or may provide objective analysis results via a software interface.
FILED Thursday, March 19, 2020
APPL NO 16/823827
ART UNIT 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image Data Processing or Generation, in General
G06T 7/0012 (20130101) Original (OR) Class
G06T 2207/10088 (20130101)
G06T 2207/30016 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 30/40 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11393614 Mine et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Susumu Mine (Niskayuna, New York);  Minfeng Xu (Ballston Lake, New York);  Anbo Wu (Clifton Park, New York);  Paul St. Mark Shadforth Thompson (Stephentown, New York)
ABSTRACT A current lead assembly for minimizing heat load to a conduction cooled superconducting magnet during a ramp operation is provided. The current lead assembly includes a vacuum chamber having a through hole to enable a first end of a current lead contact to remain outside the vacuum chamber and a second end of the current lead contact to penetrate within the vacuum chamber. A vacuum boundary wall is located between the vacuum chamber and the current lead contact. At least one superconducting magnet is arranged inside of the vacuum chamber and includes a magnet lead. A second end of the current lead contact is coupled to the magnet lead via an internal lead. A vacuum cap is removably disposed to sealingly encompass therein the first end of the current lead contact during a first state of operation. The first end of the current lead contact is arranged to contact a power supply during a second state of operation, wherein the contact occurs exterior the vacuum chamber.
FILED Friday, February 28, 2020
APPL NO 16/804645
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 6/04 (20130101)
H01F 6/008 (20130101) Original (OR) Class

Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors
H01R 4/68 (20130101)

Installation of Electric Cables or Lines, or of Combined Optical and Electric Cables or Lines
H02G 15/34 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11393974 Agarwal et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
Non-Profit Organization (NPO)
Kentucky Science and Technology Corporation (KSTC)
U.S. State Government
Commonwealth of Kentucky
Kentucky Cabinet for Economic Development (KY-CED)
APPLICANT(S) Signal Solutions, LLC (Lexington, Kentucky)
ASSIGNEE(S) Signal Solutions, LLC (Lexington, Kentucky)
INVENTOR(S) Anuj Agarwal (Lexington, Kentucky);  Michael E. Lhamon (Lexington, Kentucky)
ABSTRACT Sensing an environment by confining a monitored live subject in an enclosure, detecting an effect on a coaxial piezoelectric cable resulting from the monitored live subject, wherein the coaxial piezoelectric cable is located at least proximate to the enclosure, and deriving information about a state of the monitored live subject based on the detected effect.
FILED Tuesday, October 13, 2020
APPL NO 17/069419
ART UNIT 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 29/005 (20130101)

Diagnosis; Surgery; Identification
A61B 5/113 (20130101)
A61B 5/0816 (20130101)
A61B 5/4812 (20130101)
A61B 5/4818 (20130101)
A61B 5/6888 (20130101)
A61B 5/6892 (20130101)
A61B 2503/40 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 41/45 (20130101) Original (OR) Class
H01L 41/087 (20130101)
H01L 41/193 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 11388945 Snow et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Keyport, Washington)
INVENTOR(S) Jacob Snow (Bremerton, Washington);  Jacob Yates (Poulsbo, Washington);  Nathan Schuyler (Silverdale, Washington)
ABSTRACT A face shield for use with protective headgear can be shipped flat and easily assembled from a kit of parts without the use of tools or adhesives. The face shield protects against disease, aerosols and splatter that may contain pathogens; may include a curved lower perimeter to facilitate head movements, and can be taken on and off easily.
FILED Friday, September 25, 2020
APPL NO 16/974092
ART UNIT 3732 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Hats; Head Coverings
A42B 3/18 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389069 Grudic et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) Flashback Technologies, Inc. (Boulder, Colorado);  The Regents of the University of Colorado (Denver, Colorado)
ASSIGNEE(S) Flashback Technologies, Inc. (Westfield, New Jersey);  The Regents of the University of Colorado (Denver, Colorado)
INVENTOR(S) Gregory Zlatko Grudic (Niwot, Colorado);  Steven L. Moulton (Littleton, Colorado);  Isobel Jane Mulligan (Niwot, Colorado)
ABSTRACT Tools and techniques for estimating a probability that a patient is bleeding or has sustained intravascular volume loss (e.g., due to hemodialysis or dehydration) and/or to estimate a patient's current hemodynamic reserve index, track the patient's hemodynamic reserve index over time, and/or predict a patient's hemodynamic reserve index in the future. Tools and techniques for estimating and/or predicting a patient's dehydration state. Tools and techniques for controlling a hemodialysis machine based on the patient's estimated and/or predicted hemodynamic reserve index.
FILED Thursday, July 13, 2017
APPL NO 15/649411
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/021 (20130101)
A61B 5/029 (20130101)
A61B 5/318 (20210101)
A61B 5/02028 (20130101) Original (OR) Class
A61B 5/02042 (20130101)
A61B 5/7275 (20130101)
A61B 5/14551 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 40/60 (20180101)
G16H 50/30 (20180101)

Technologies for Adaptation to Climate Change
Y02A 90/10 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389168 Greene, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) MicroVention, Inc. (Tustin, California);  University of Virginia Patent Foundation (Charlottesville, Virginia);  United States of America as Represented by the Secretary of the Navy (Silver Spring, Maryland)
ASSIGNEE(S) MicroVention, Inc. (Aliso Viejo, California);  University of Virginia Patent Foundation (Charlottesville, Virginia);  United States of America as Represented by the Secretary of the Navy (Silver Spring, Maryland)
INVENTOR(S) George R. Greene, Jr. (Costa Mesa, California);  Ivan Sepetka (Los Altos, California);  Cathy Lei (Chino Hills, California);  Rupal Nguyen (Costa Mesa, California);  Matthew J. Bradley (Silver Spring, Maryland);  Stephen T. Ahlers (Silver Spring, Maryland);  Carl S. Goforth (Silver Spring, Maryland);  James R. Stone (Charlottesville, Virginia)
ABSTRACT A temporary aortic occlusion device is disclosed, having an expandable locator portion and an expandable occlusion portion. The expandable locator portion assists a user in determining whether the distal end of the device has been advanced within a patient's aorta, and the occlusion portion is expanded to occlude the patient's aorta, preferably below the renal arteries.
FILED Tuesday, August 29, 2017
APPL NO 15/690152
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/1204 (20130101)
A61B 17/12109 (20130101) Original (OR) Class
A61B 17/12136 (20130101)
A61B 17/12168 (20130101)
A61B 17/12172 (20130101)
A61B 17/12177 (20130101)
A61B 2017/00115 (20130101)
A61B 2017/1205 (20130101)
A61B 2090/0807 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389169 Greene, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) MicroVention, Inc. (Tustin, California);  University of Virginia Patent Foundation (Charlottesville, Virginia);  United States of America As Represented By The Secretary Of The Navy (Silver Spring, Maryland)
ASSIGNEE(S) Microvention, Inc. (Tustin, California);  University of Virginia Patent Foundation (Charlottesville, Virginia);  United States of America as Represented by the Secretary of the Navy (Silver Spring, Maryland)
INVENTOR(S) George R. Greene, Jr. (Costa Mesa, California);  Ivan Sepetka (Los Altos, California);  Cathy Lei (Chino Hills, California);  Rupal Nguyen (Costa Mesa, California);  Matthew J. Bradley (Silver Spring, Maryland);  Stephen T. Ahlers (Silver Spring, Maryland);  Carl W. Goforth (Silver Spring, Maryland);  James R. Stone (Charlottesville, Virginia)
ABSTRACT A temporary aortic occlusion device is disclosed, having an expandable locator portion and an expandable occlusion portion. The expandable locator portion assists a user in determining whether the distal end of the device has been advanced within a patient's aorta, and the occlusion portion is expanded to occlude the patient's aorta, preferably below the renal arteries.
FILED Thursday, February 28, 2019
APPL NO 16/289485
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/1204 (20130101)
A61B 17/1214 (20130101)
A61B 17/12109 (20130101) Original (OR) Class
A61B 17/12136 (20130101)
A61B 17/12172 (20130101)
A61B 17/12177 (20130101)
A61B 2017/00942 (20130101)
A61B 2017/1205 (20130101)
A61B 2090/0807 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389400 Batchinsky et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
Defense Innovation Unit Experimental (DIU)
Defense Innovation Unit Experimental (DIUX)
APPLICANT(S) Qool Therapeutics, Inc. (Menlo Park, California)
ASSIGNEE(S) The Government of The United States, as Represented by The Secretary of the Army (Fort Detrick, Maryland)
INVENTOR(S) Andriy Batchinsky (San Antonio, Texas);  Ben Antebi (Helotes, Texas);  Brendan M. Beely (San Antonio, Texas);  Leopoldo C. Cancio (San Antonio, Texas);  Amir Belson (Savyon, Israel);  Beverly Huss (Menlo Park, California);  Edward J. Hayes (San Jose, California);  Jeff G. Haydon (Menlo Park, California)
ABSTRACT A treatment system delivers a breathing gas and frozen stem cells or other biologic particles (FBP) to a bronchus of a lung of a patient in order to treat lung and other conditions. The breathing gas and the FBP are usually delivered through separate lumens. The FBP may be delivered concurrently with other frozen particles, such as frozen saline particles (FSP). The FBP/FSP will remain frozen at all times from preparation to delivery, and will thaw only after they are released into the lung.
FILED Wednesday, July 25, 2018
APPL NO 16/045046
ART UNIT 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 7/00 (20130101)
A61F 7/12 (20130101)
A61F 2007/0064 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0075 (20130101) Original (OR) Class
A61K 9/0078 (20130101)
A61K 35/28 (20130101)
A61K 35/50 (20130101)
A61K 35/545 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 11/00 (20130101)
A61M 11/001 (20140204)
A61M 16/14 (20130101)
A61M 16/201 (20140204)
A61M 2202/064 (20130101)
A61M 2202/0437 (20130101)
A61M 2205/366 (20130101)
A61M 2205/3368 (20130101)
A61M 2205/3606 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 11/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389484 Aggarwal et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Mesoblast International Sarl (Meyrin, Switzerland)
ASSIGNEE(S) Mesoblast International Sárl (Meyrin, Switzerland)
INVENTOR(S) Sudeepta Aggarwal (North Potomac, Maryland);  Mark F. Pittenger (Severna Park, Maryland);  Timothy Varney (Baltimore, Maryland)
ABSTRACT Compositions and methods of promoting wound healing in a human by administering to the human mesenchymal stem cells in an effective amount.
FILED Monday, December 10, 2018
APPL NO 16/214485
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/28 (20130101) Original (OR) Class
A61K 38/2026 (20130101)
A61K 38/2066 (20130101)
A61K 45/06 (20130101)
A61K 2035/124 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 11/00 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0662 (20130101)
C12N 5/0663 (20130101)
C12N 5/0664 (20130101)
C12N 5/0665 (20130101)
C12N 5/0666 (20130101)
C12N 5/0667 (20130101)
C12N 5/0668 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389532 Clark et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington);  Abacus Bioscience, Inc. (Sammamish, Washington)
INVENTOR(S) Edward A. Clark (Seattle, Washington);  Che-Leung Law (Seattle, Washington);  Deborah Fuller (Seattle, Washington);  Michael Gale (Seattle, Washington)
ABSTRACT Compositions including a CD180 binding ligand and a linked Hepatitis B antigen and their use are disclosed. The Hepatitis B antigen includes Hepatitis B virus pre-S1 and/or pre-S2 region of the HBV envelope protein (HBVpreS1/S2Ag), L-HBsAg, MHBsAg, S-HBsAg, or antigenic fragments or mutants thereof.
FILED Thursday, November 15, 2018
APPL NO 16/764950
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/292 (20130101) Original (OR) Class
A61K 2039/6056 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/20 (20180101)

Peptides
C07K 16/2878 (20130101)
C07K 16/2896 (20130101)
C07K 2317/56 (20130101)
C07K 2317/524 (20130101)
C07K 2317/526 (20130101)
C07K 2317/622 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389866 Rosi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Nathaniel L. Rosi (Pittsburgh, Pennsylvania);  Andrea David Merg (Pittsburgh, Pennsylvania);  Soumitra Punekar (Pittsburgh, Pennsylvania)
ABSTRACT Described herein are metal nanoparticle superstructures and methods and compounds for making the same.
FILED Thursday, December 14, 2017
APPL NO 15/842625
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/07 (20220101) Original (OR) Class
B22F 1/054 (20220101)
B22F 1/0553 (20220101)
B22F 9/24 (20130101)
B22F 2301/255 (20130101)

Nanostructures Formed by Manipulation of Individual Atoms, Molecules, or Limited Collections of Atoms or Molecules as Discrete Units; Manufacture or Treatment Thereof
B82B 3/0009 (20130101)
B82B 3/0066 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)
B82Y 40/00 (20130101)

Heterocyclic Compounds
C07D 249/04 (20130101)

Peptides
C07K 7/08 (20130101)
C07K 17/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390198 Evans et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) PRATT and MILLER ENGINEERING AND FABRICATION, INC. (New Hudson, Michigan)
ASSIGNEE(S) PRATT and MILLER ENGINEERING AND FABRICATION, LLC (New Hudson, Michigan)
INVENTOR(S) Celyn M. Evans (Milford, Michigan);  Kevin R. Kwiatkowski (Ann Arbor, Michigan)
ABSTRACT A seat having a seat back pivotally connected to a seat pan, the seat back and the seat pan independently pivotal. At the pivot between the seat back and the seat pan there is a rotary energy attenuation device. The rotary energy attenuating device cooperates with a track system along the length of seat longitudinal members allowing for different directions of travel and height adjustment. The vehicle seat offers passive or active protection from impact and sudden acceleration due to accident or explosive events and is capable of automatically resetting.
FILED Wednesday, April 28, 2021
APPL NO 17/243013
ART UNIT 3636 — Static Structures, Supports and Furniture
CURRENT CPC
Seats Specially Adapted for Vehicles; Vehicle Passenger Accommodation Not Otherwise Provided for
B60N 2/4214 (20130101)
B60N 2/42745 (20130101) Original (OR) Class
B60N 2/42772 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390373 Collmus et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) John P. Collmus (Camarillo, California);  Nicholas J. Duckworth (Annapolis, Maryland);  Scott M. Reider (Camarillo, California);  Chong T. Oh (Camarillo, California)
ABSTRACT The embodiments are directed to an interface mount between a vehicle steering/control device and a mobile computer protective case. The interface mount has two sides. One side of the interface mount is attached to the vehicle steering/control device. The other side of the interface mount is attached to an AMPS hole pattern plate.
FILED Thursday, June 10, 2021
APPL NO 17/343973
ART UNIT 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeroplanes; Helicopters
B64C 13/0423 (20180101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390382 Anderson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Michael Anderson (Colorado Springs, Colorado);  Benjamin Stark (Dixon, California);  Jeffrey Burnett (Severna Park, Maryland);  Tyler Copien (San Angelo, Texas);  Candice Roberts (Milford, Virginia)
ABSTRACT A system for deploying an unmanned aerial vehicle in a target region. The system includes a pod configured to be deployed from an air craft in a first region remote from the target region. The pod includes a capsule housing portion and a capsule ejection system in operative communication with the capsule housing portion. A capsule is dimensioned and configured to be disposed in the capsule housing portion as the pod is deployed from the aircraft and is ejected from the capsule housing portion by the capsule ejection system in a second region remote from the first region and the target region. The capsule includes a UAV housing portion dimensioned and configured to encase the unmanned aerial vehicle and a UAV ejection system in operative communication with the UAV housing portion for deploying the unmanned aerial vehicle in the target region.
FILED Monday, July 08, 2019
APPL NO 16/504563
ART UNIT 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeroplanes; Helicopters
B64C 39/024 (20130101) Original (OR) Class
B64C 2201/027 (20130101)
B64C 2201/082 (20130101)
B64C 2201/108 (20130101)
B64C 2201/206 (20130101)

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 1/12 (20130101)
B64D 5/00 (20130101)
B64D 17/80 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390517 Endean et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Honeywell International Inc. (Morris Plains, New Jersey)
ASSIGNEE(S) Honeywell International Inc. (Charlotte, North Carolina)
INVENTOR(S) Daniel Endean (Plymouth, Minnesota);  John Reinke (Plymouth, Minnesota)
ABSTRACT Systems and methods for suppressing bias in a non-degenerate vibratory structure are provided. In certain embodiments, a vibratory structure includes a first proof mass; a second proof mass, wherein the first proof mass and the second proof mass are driven into motion along a first axis, wherein the first proof mass and the second proof mass move in anti-phase along a second axis, wherein the motion of the first proof mass and the second proof mass along the second axis is such that the centers of mass of the first proof mass and the second proof mass move collinearly along a same axis.
FILED Tuesday, June 30, 2020
APPL NO 16/917292
ART UNIT 2861 — Printing/Measuring and Testing
CURRENT CPC
Microstructural Devices or Systems, e.g Micromechanical Devices
B81B 3/0021 (20130101) Original (OR) Class
B81B 3/0072 (20130101)
B81B 7/0058 (20130101)
B81B 2201/0242 (20130101)
B81B 2203/0118 (20130101)

Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 19/574 (20130101)
G01C 19/5719 (20130101)
G01C 19/5747 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390636 Chaloux et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Research Laboratory (NRL)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Brian L. Chaloux (Alexandria, Virginia);  Albert Epshteyn (Potomac, Maryland);  Thomas J. Dabrow (College Park, Maryland)
ABSTRACT Described herein is the preparation of carbon phosphonitride pre-polymers that are soluble in organic solvents and can be further thermoset into carbon phosphonitride extended solids (i.e. films, monoliths, etc.) with an approximate empirical formula of C3N3P.
FILED Tuesday, July 27, 2021
APPL NO 17/443750
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/5036 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390888 Horwitz et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Amyris, Inc. (Emeryville, California)
ASSIGNEE(S) AMYRIS, INC. (Emeryville, California)
INVENTOR(S) Andrew Horwitz (Emeryville, California);  Kristy Michelle Hawkins (Emeryville, California);  Max Schubert (Emeryville, California);  Wayne Szeto (Emeryville, California)
ABSTRACT Provided herein are methods of integrating one or more exogenous nucleic acids into one or more selected target sites of a host cell genome. in certain embodiments, the methods comprise contacting the host cell genome with one or more integration polynucleotides comprising an exogenous nucleic acid to be integrated into a genomic target site, a nuclease capable of causing a break at the genomic target site, and a linear nucleic acid capable of homologous recombination with itself or with one or more additional linear nucleic acids contacted with the population of cells, whereupon said homologous recombination results in formation of a circular extrachromosomal nucleic acid comprising a coding sequence for a selectable marker. in some embodiments, the methods further comprise selecting a host cell that expresses the selectable marker.
FILED Wednesday, March 11, 2020
APPL NO 16/816172
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/111 (20130101)
C12N 15/902 (20130101)
C12N 15/907 (20130101) Original (OR) Class
C12N 2310/20 (20170501)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6897 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390923 Chinnaiyan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Arul Chinnaiyan (Plymouth, Michigan);  John Prensner (Ann Arbor, Michigan);  Matthew Iyer (Ann Arbor, Michigan)
ABSTRACT The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to ncRNAs as diagnostic markers and clinical targets for prostate, lung, breast and pancreatic cancer.
FILED Wednesday, June 26, 2019
APPL NO 16/453195
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/11 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/16 (20130101)
C12Q 2600/118 (20130101)
C12Q 2600/158 (20130101)
C12Q 2600/178 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390963 Tassev
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Vladimir Tassev (Beavercreek, Ohio)
ABSTRACT A method of performing heteroepitaxy comprises exposing a substrate to a carrier gas, a first precursor gas, a Group II/III element, and a second precursor gas, to form a heteroepitaxial growth of one of GaAs, AlAs, InAs, GaP, InP, ZnSe, GaSe, CdSe, InSe, ZnTe, CdTe, GaTe, HgTe, GaSb, InSb, AlSb, CdS, GaN, and AlN on the substrate; wherein the substrate comprises one of GaAs, AlAs, InAs, GaP, InP, ZnSe, GaSe, CdSe, InSe, ZnTe, CdTe, GaTe, HgTe, GaSb, InSb, AlSb, CdS, GaN, and AlN; wherein the carrier gas is H2, wherein the first precursor is HCl, the Group II/III element comprises at least one of Zn, Cd, Hg, Al, Ga, and In; and wherein the second precursor is one of AsH3 (arsine), PH3 (phosphine), H2Se (hydrogen selenide), H2Te (hydrogen telluride), SbH3 (hydrogen antimonide), H2S (hydrogen sulfide), and NH3 (ammonia). The process may be an HVPE (hydride vapor phase epitaxy) process.
FILED Friday, December 11, 2020
APPL NO 17/119131
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 25/04 (20130101) Original (OR) Class
C30B 25/18 (20130101)
C30B 29/42 (20130101)
C30B 29/44 (20130101)
C30B 29/48 (20130101)
C30B 29/406 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/3556 (20130101)
G02F 1/3558 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/0254 (20130101)
H01L 21/0262 (20130101)
H01L 21/02293 (20130101)
H01L 21/02389 (20130101)
H01L 21/02392 (20130101)
H01L 21/02395 (20130101)
H01L 21/02398 (20130101)
H01L 21/02458 (20130101)
H01L 21/02461 (20130101)
H01L 21/02463 (20130101)
H01L 21/02466 (20130101)
H01L 21/02505 (20130101)
H01L 21/02543 (20130101)
H01L 21/02546 (20130101)
H01L 21/02549 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11391158 Senile et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Defense Contract Management Agency (DCMA)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Darrell Glenn Senile (Oxford, Ohio);  Matthew Mark Weaver (Loveland, Ohio);  Alexander Martin Sener (Cincinnati, Ohio)
ABSTRACT Airfoil assemblies for gas turbine engines are provided. For example, an airfoil assembly comprises an airfoil, an inner band defining an inner opening shaped complementary to an inner end of the airfoil, and an outer band defining an outer opening shaped complementary to an outer end of the airfoil. The airfoil inner end is received with the inner opening, and the airfoil outer end is received within the outer opening. A strut extends radially through an airfoil cavity. A first pad is defined at a first radial location within the cavity. A second pad is defined within the cavity at a second, different radial location. In some embodiments, the airfoil assembly inner band includes a first inner flange, through which the inner band is secured to a support structure, and the outer band includes a first outer flange, through which the outer band is secured to a support structure.
FILED Tuesday, February 09, 2021
APPL NO 17/170988
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/142 (20130101) Original (OR) Class
F01D 5/147 (20130101)
F01D 5/284 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2240/305 (20130101)
F05D 2240/306 (20130101)
F05D 2250/711 (20130101)
F05D 2250/712 (20130101)
F05D 2300/6033 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11391247 Borissov et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) FireFly Aerospace Inc. (Cedar Park, Texas)
ASSIGNEE(S) FIREFLY AEROSPACE INC. (Cedar Park, Texas)
INVENTOR(S) Anatoli Alimpievich Borissov (Sugar Land, Texas);  Thomas Edward Markusic (Georgetown, Texas)
ABSTRACT A liquid rocket engine cools a thruster body by pumping propellant through cooling channels integrated in the thruster body between internal and external surfaces. One or more of the cooling channel surfaces has a variable depth along a thrust axis to mix propellant flow and destroy thermal stratification, such as a depth that varies with a repeated contiguous sinusoidal form along the thrust axis. Fuel passed through the cooling channels injects from the combustion chamber wall towards a central portion of the combustion chamber to cross impinge with oxygen injected at the combustion chamber head so that a toroidal vortex forms to enhance propellant mixing.
FILED Thursday, January 24, 2019
APPL NO 16/256210
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Jet-propulsion Plants
F02K 9/52 (20130101)
F02K 9/62 (20130101)
F02K 9/64 (20130101)
F02K 9/972 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11391550 Hardt et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Lee R. Hardt (Ridgecrest, California);  Donald L. Burnett (Spearfish, South Dakota);  Josiah S. Garfield (Ridgecrest, California);  Robert A. Koontz (Anchorage, Alaska);  Eric K. Wooding (Ridgecrest, California);  Que T. BuiDang (Ridgecrest, California)
ABSTRACT The disclosed embodiments are directed to enhancing insensitive munitions performance. Some of the embodiments employ an outgassing pad having unique geometrical configurations, compositions, and positioning. Other embodiments rely on using thermally-releasable components to foster billet expulsion. Additional embodiments combine both aspects into entire cook-off mitigation systems for insensitive munitions improvements.
FILED Thursday, May 07, 2020
APPL NO 16/868734
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance
F41A 17/16 (20130101)

Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 12/20 (20130101)
F42B 12/207 (20130101) Original (OR) Class
F42B 39/14 (20130101)
F42B 39/20 (20130101)

Ammunition Fuzes; Arming or Safety Means Therefor
F42C 19/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11391562 Nguyen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
Naval Air Warfare Center Aircraft Division (NAWCAD)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) iSenseCloud, Inc. (San Jose, California)
ASSIGNEE(S) iSenseCloud, Inc. (Milpitas, California)
INVENTOR(S) An-Dien Nguyen (Fremont, California);  An H. Nguyen (Fremont, California)
ABSTRACT A fiber optic voltage conditioner, and method therefor, generally relate to voltage conditioning. In such a fiber optic voltage conditioner, there is a laser, and an optical circulator is coupled to receive a light signal from the laser. A controller is coupled to the laser and is configured to generate first control information for wavelength-drift control of the laser. A data acquisition module is coupled to the controller and is configured to generate second control information for the controller for adjustment of the first control information. A photodetector is coupled to the optical circulator to receive a returned optical signal and is coupled to the data acquisition module to provide an analog output signal thereto. The photodetector is configured to generate the analog output signal responsive to the returned optical signal. The data acquisition module is configured to generate the second control information using the analog output signal.
FILED Thursday, February 20, 2020
APPL NO 16/796447
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 11/165 (20130101) Original (OR) Class

Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for
G01K 11/3206 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 5/0612 (20130101)
H01S 5/0617 (20130101)
H01S 5/0622 (20130101)
H01S 5/0687 (20130101)
H01S 5/02415 (20130101)
H01S 5/4087 (20130101)
H01S 5/06804 (20130101)
H01S 5/06808 (20130101)
H01S 5/06837 (20130101)

Transmission
H04B 10/572 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11391734 Gopinath et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Ashwin Gopinath (Pasadena, California);  Paul W. K. Rothemund (Pasadena, California)
ABSTRACT Bistable devices are constructed using a polynucleotide platform for sensing molecular events such as binding or conformational changes of target molecules. Uses include measurement of target concentration, measuring the effect of environmental condition (such as heat, light, or pH) on the target, or screening a library for molecules that bind the target or modulate its biological function. Devices comprise three regions: a top lid, bottom lid, and flexible linker or hinge between them. A device has an open configuration in which the top and bottom lid are separated, and a closed configuration they are bound close together. Binding domains or variations of the target molecule are fixed to a device so that when the molecular event occurs, the device switches from open to closed, or vice versa, which generates a signal. Optimal device design is determined by the signal modality (optical or electronic) used to measure closure of surface-immobilized devices.
FILED Thursday, March 28, 2019
APPL NO 16/367240
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/11 (20130101)
C12N 2310/20 (20170501)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/47 (20130101)
G01N 21/553 (20130101)
G01N 21/6428 (20130101)
G01N 33/544 (20130101)
G01N 33/54373 (20130101) Original (OR) Class
G01N 2021/6439 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11391806 Owen
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
Combat Capabilities Development Command (CCDC)
Aviation and Missile Center (CCDC AVMC)
APPLICANT(S) Henry S. Owen (Medford, New Jersey)
ASSIGNEE(S) HENRY S. OWEN LLC (Medford, New Jersey)
INVENTOR(S) Henry S. Owen (Medford, New Jersey)
ABSTRACT Methods and systems disclosed herein may include receiving signals from a transmitter in a receiver; determine a bias of the transmitter and receiver; generating expected observations, based on the bias, corresponding to the received signals; and calculate a building height based on a power level of the received signals and a power level of the expected observations.
FILED Tuesday, March 03, 2020
APPL NO 16/807789
ART UNIT 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 1/02 (20130101) Original (OR) Class
G01S 5/021 (20130101)
G01S 5/0252 (20130101)
G01S 5/0294 (20130101)
G01S 19/22 (20130101)
G01S 19/40 (20130101)
G01S 19/071 (20190801)
G01S 19/072 (20190801)
G01S 19/428 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11391832 Burke
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) David Burke (Boston, Massachusetts)
ABSTRACT A phase Doppler radar system may comprise a pulse Doppler receiver/transmitter (R/T) subsystem coupled with a processing subsystem. The system may determine target velocity and target detection events by collecting pulses from the pulse Doppler R/T subsystem, determine an undifferentiated phase of each of the pulses, differentiate the pulses, and determine a differentiated phase of each of the pulses. The system may perform a linear fit of the differentiated phases of the pulses to produce a slope and an intercept. The system may determine a set of initial estimates of coefficients of a nonlinear fit equation. The system may perform iterations of a nonlinear least squares fit, beginning with the initial coefficient estimates, to produce a non-linear fit result. The system may determine a goodness-of-fit (GoF) statistic associated with the nonlinear fit result, and declare a detection event when the GoF is superior to a GoF statistic associated Gaussian noise.
FILED Wednesday, October 10, 2018
APPL NO 16/156411
ART UNIT 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/292 (20130101)
G01S 7/414 (20130101)
G01S 13/53 (20130101)
G01S 13/582 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11391866 Barton, III et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Office of Emerging Frontiers and Multidisciplinary Activities (EFMA)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) David Russell Barton, III (Somerville, Massachusetts);  Mark Lawrence (Saint Louis, Missouri);  Jennifer A. Dionne (Menlo Park, California);  Jefferson Dixon (Staten Island, New York)
ABSTRACT High quality factor electromagnetic metasurfaces are provided. The metasurface is configured to have in plane guided-mode resonances (e.g., corresponding to waveguide modes or the like). Coupling features are included in the metasurface that are configured to couple free-space radiation to the guided mode resonances. The resulting structures have a high-Q response to free-space radiation and can be used for various applications, such as beam splitting, beam steering, and beam focusing or defocusing.
FILED Wednesday, November 04, 2020
APPL NO 17/089384
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 1/002 (20130101)
G02B 1/005 (20130101) Original (OR) Class
G02B 6/12 (20130101)
G02B 6/26 (20130101)
G02B 27/1086 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11391896 Fard
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
INVENTOR(S) Erfan M. Fard (Tucson, Arizona)
ABSTRACT In accordance with a method for transferring optical signals to and from an optical component incorporated in a photonic integrated circuit (PIC), an incoming optical signal in a first polarization state is received at a splitter section of a polarization splitter rotator (PSR). The splitter section causes the optical signal to be directed to a first waveguide of a pair of waveguides of the PSR. One of the waveguides rotates a polarization state of an optical signal traversing therethrough into an orthogonal polarization state and the other waveguide maintains a polarization state of an optical signal traversing therethrough. The incoming optical signal is directed from the first waveguide to the optical component. An outgoing optical signal is received in a second waveguide of the pair such that the outgoing optical signal traverses the second waveguide and the splitter section to be output by the PSR.
FILED Thursday, May 16, 2019
APPL NO 17/056578
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/4213 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11391959 Kokubun et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
ASSIGNEE(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S) Daniel N. Kokubun (Waipahu, Hawaii);  Mark Branham (Trafalgar, Indiana);  Sidney Pang (Kaneohe, Hawaii);  Mark Segawa (Wahiawa, Hawaii)
ABSTRACT Techniques are provided for laser illumination employing closely spaced laser beams. A system implementing the techniques according to an embodiment includes a semi-cylindrical optical block comprising a curved surface and a planar surface. The system further includes two laser sources configured to direct first and second laser beams to the curved surface, such that the first laser beam enters and exits the block parallel to and offset from the planar surface by a selected translation distance, and the second laser beam enters the block at a critical angle relative to the planar surface. The critical angle is associated with total internal reflection of the second laser beam along the planar surface, such that the second laser beam exits the block parallel to, and separated from, the first laser beam exiting the optical block. The separation of the exiting first and second laser beams is controlled by the selected translation distance.
FILED Wednesday, August 21, 2019
APPL NO 16/546758
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 27/48 (20130101)
G02B 27/108 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11392529 Linderman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) GOVERMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (Rome, New York)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Rome, New York)
INVENTOR(S) Mark H Linderman (Rome, New York);  Qing Wu (Manlius, New York);  Dennis Fitzgerald (Sauquoit, New York)
ABSTRACT An apparatus for a microprocessor computer system and method for configuring the same where said microprocessor computer system comprises a processor core and at least one hardware buffer FIFO with memory-mapped head and tail that handles data movement among the processor cores, networks, raw data input and outputs, and memory. The method for configuring said microprocessor computer system comprises utilizing a FIFO auxiliary processor to process said data traversing said hardware FIFO; utilizing said hardware FIFOs to efficiently pipe data through functional blocks; and utilizing a FIFO controller to perform DMA operations that include non-unit-stride access patterns and transfers among processor cores, networks, raw data input and outputs, memory, and other memory-mapped hardware FIFOs.
FILED Tuesday, May 28, 2019
APPL NO 16/423282
ART UNIT 2181 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 13/404 (20130101) Original (OR) Class
G06F 13/4022 (20130101)
G06F 13/4031 (20130101)
G06F 13/4081 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11392699 Rubin
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) SPAWAR Systems Center Pacific (San Diego, California)
ASSIGNEE(S) United States of America as Represented by Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Stuart H. Rubin (San Diego, California)
ABSTRACT A device, method, and system for synthesizing variants of semantically equivalent computer source code using computer source code components to protect against cyberattacks. An input constraint, an output constraint, and a schema are received from a user. A component-based synthesizer generates first computer source code including a first computer source code component based on the input constraint, the output constraint, and the schema. The component-based synthesizer generates second computer source code including a second computer source code component based on the input constraint, the output constraint, and the schema. The second computer source code is generated as a semantically equivalent variant of the first computer source code to provide for protection against a cyberattack. The invention may also include a dynamic component library.
FILED Wednesday, March 20, 2019
APPL NO 16/359821
ART UNIT 2191 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 8/36 (20130101)
G06F 8/70 (20130101)
G06F 21/57 (20130101) Original (OR) Class
G06F 2221/033 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11392827 Rubin
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (San Diego, California)
ASSIGNEE(S) United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Stuart H. Rubin (San Diego, California)
ABSTRACT A method includes providing a set of deep learning neural networks where no pair of deep learning neural networks within the set of deep learning neural networks produces a semantically equivalent output by design. An input to the set of deep learning neural networks is provided, where responsive to the input, one or more of the deep learning neural networks produces an output. The output of the deep learning neural networks is input into a case-based reasoning (CBR) system. The CBR system generates an output responsive to the input received by the CBR system if the input received by the CBR system is known by the CBR system. The output of the CBR system is then determined to be a correct/incorrect output. One of the deep learning neural networks is trained on the correct output if the correct output is specific to the particular deep learning neural network.
FILED Tuesday, July 17, 2018
APPL NO 16/037683
ART UNIT 2486 — Recording and Compression
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101) Original (OR) Class
G06N 3/0454 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11393353 Del Sesto et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
U.S. Army Picatinny Arsenal (PICA)
APPLICANT(S) UI LABS (Chicago, Illinois)
ASSIGNEE(S) UI LABS (Chicago, Illinois)
INVENTOR(S) Antonio Del Sesto (Chicago, Illinois);  Rodrigo Santos Quintella Freire (Chicago, Illinois);  Alejandro Velez (Park Ridge, Illinois)
ABSTRACT An industrial operations network is disclosed herein. More particularly the disclosure may pertain to an industrial operations network designed for facilitating the training of security concepts for industrial operations. In one embodiment, an apparatus for training industrial security concepts is disclosed. The apparatus may comprise a portable industrial operations network comprising: at least one router; at least one firewall; at least one programmable logic controller; and at least one display connected to the portable industrial operations network, said at least one display adapted to display, at different times, normal operating conditions of said portable industrial operations network and security fault conditions in said portable industrial operations network.
FILED Wednesday, September 30, 2020
APPL NO 17/039540
ART UNIT 3715 — Amusement and Education Devices
CURRENT CPC
Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 5/06 (20130101) Original (OR) Class
G09B 9/00 (20130101)
G09B 19/0053 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11393355 Warren et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) BETA AIR, LLC (South Burlington, Vermont)
ASSIGNEE(S) BETA AIR, LLC (South Burlington, Vermont)
INVENTOR(S) Nicholas Granger Warren (Burlington, Vermont);  Charles C. Guthrie (Burlington, Vermont);  Nicholas Moy (Burlington, Vermont);  Alexander Hoekje List (South Burlington, Vermont)
ABSTRACT A system for flight simulation of an electric aircraft. The system includes a pilot control. The pilot control is configured to receive an input from a user. The system includes a pilot command that is generated by the pilot control. The system includes a computing device configured to generate a simulation. The simulation includes an electric aircraft model. The electric aircraft model is configured to simulate a performance of an electric aircraft. The performance is determined by at least the pilot command. The simulation is configured to provide feedback to the user based on the performance of the electric aircraft. The simulation is further configured to updated the electric aircraft model as a function of the pilot command.
FILED Tuesday, July 13, 2021
APPL NO 17/373889
ART UNIT 3715 — Amusement and Education Devices
CURRENT CPC
Electric Digital Data Processing
G06F 30/20 (20200101)

Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 9/24 (20130101)
G09B 9/085 (20130101) Original (OR) Class
G09B 9/165 (20130101)
G09B 9/301 (20130101)
G09B 9/307 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11393558 Bo et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
ASSIGNEE(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S) Chunkun Bo (Charlottesville, Virginia);  Kevin Skadron (Charlottesville, Virginia);  Elaheh Sadredini (Charlottesville, Virginia);  Vinh Dang (Charlottesville, Virginia)
ABSTRACT A method of operating a finite state machine circuit can be provided by determining if a target sequence of characters included in a string of reference characters occurs within a specified difference distance using states indicated by the finite state machine circuit to indicate a number of character mis-matches between the target sequence of characters and a respective sequence of characters within the string of reference characters.
FILED Friday, February 16, 2018
APPL NO 15/932287
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Electric Digital Data Processing
G06F 16/90344 (20190101)

Computer Systems Based on Specific Computational Models
G06N 5/047 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 30/00 (20190201) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11393970 Majkic et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) University of Houston System (Houston, Texas)
ASSIGNEE(S) University of Houston System (Houston, Texas)
INVENTOR(S) Goran Majkic (Houston, Texas);  Venkat Selvamanickam (Houston, Texas)
ABSTRACT A superconductor tape and method for manufacturing, measuring, monitoring, and controlling same are disclosed. Embodiments are directed to a superconductor tape which includes a superconductor film overlying a buffer layer which overlies a substrate. In one embodiment, the superconductor film is defined as having a c-axis lattice constant higher than 11.74 Angstroms. In another embodiment, the superconductor film comprises BaMO3, where M=Zr, Sn, Ta, Nb, Hf, or Ce, and which has a (101) peak of BaMO3 elongated along an axis that is between 60° to 90° from an axis of the (001) peaks of the superconductor film. These and other embodiments achieve well-aligned nanocolumnar defects and thus a high lift factor, which can result in superior critical current performance of the tape in, for example, high magnetic fields.
FILED Tuesday, August 29, 2017
APPL NO 16/329658
ART UNIT 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 39/126 (20130101)
H01L 39/143 (20130101)
H01L 39/2441 (20130101)
H01L 39/2461 (20130101) Original (OR) Class

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 40/60 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11393976 Jarillo-Herrero et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Energy (DOE)
Office of Science (DOE-SC)
Ames Laboratory (AL)
Federally Funded Research and Development Center (FFRDC)
Operated by Iowa State University (IASTATE) at Ames, IA
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) Pablo Jarillo-Herrero (Cambridge, Massachusetts);  Qiong Ma (Cambridge, Massachusetts);  Nuh Gedik (Watertown, Massachusetts);  Suyang Xu (Cambridge, Massachusetts);  Zhiren Zheng (Cambridge, Massachusetts)
ABSTRACT An ultrathin, carbon-based memristor with a moiré superlattice potential shows prominent ferroelectric resistance switching. The memristor includes a bilayer material, such as Bernal-stacked bilayer graphene, encapsulated between two layers of a layered material, such as hexagonal boron nitride. At least one of the encapsulating layers is rotationally aligned with the bilayer to create the moiré superlattice potential. The memristor exhibits ultrafast and robust resistance switching between multiple resistance states at high temperatures. The memristor, which may be volatile or nonvolatile, may be suitable for neuromorphic computing.
FILED Tuesday, November 10, 2020
APPL NO 17/094141
ART UNIT 2827 — Semiconductors/Memory
CURRENT CPC
Static Stores
G11C 13/0069 (20130101)
G11C 2213/35 (20130101)
G11C 2213/53 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 45/10 (20130101) Original (OR) Class
H01L 45/142 (20130101)
H01L 45/143 (20130101)
H01L 45/148 (20130101)
H01L 45/149 (20130101)
H01L 45/1206 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11394017 Eskra et al.
FUNDED BY
Department of Defense (DOD)
Defense Logistics Agency (DLA)
APPLICANT(S) Eskra Technical Products, Inc. (Saukville, Wisconsin)
ASSIGNEE(S) Eskra Technical Products, Inc. (Saukville, Wisconsin)
INVENTOR(S) Michael David Eskra (Saukville, Wisconsin);  Paula Margaret Ralston (Frederick, Maryland);  Rodney Mortensen LaFollette (South Jordan, Utah);  James Bernard Nowakowski (Washburn, Wisconsin)
ABSTRACT A solventless system for fabricating electrodes includes a mechanism for feeding a substrate through the system, a first application region comprised of a first device for applying a first layer to the substrate, wherein the first layer is comprised of an active material mixture and a binder, and the binder includes at least one of a thermoplastic material and a thermoset material, and the system includes a first heater positioned to heat the first layer.
FILED Monday, May 17, 2021
APPL NO 17/302944
ART UNIT 1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/0404 (20130101) Original (OR) Class
H01M 4/0419 (20130101)
H01M 4/622 (20130101)
H01M 4/623 (20130101)
H01M 4/625 (20130101)
H01M 4/1391 (20130101)
H01M 4/1393 (20130101)
H01M 4/1395 (20130101)
H01M 10/0565 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11394062 Sloop
FUNDED BY
Department of Defense (DOD)
Defense Logistics Agency (DLA)
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) Hulico LLC (Bend, Oregon)
ASSIGNEE(S) HULICO LLC (Bend, Oregon)
INVENTOR(S) Steven E. Sloop (Bend, Oregon)
ABSTRACT Examples are disclosed of methods to recycle positive-electrode material of a lithium-ion battery. One example provides a method including relithiating the positive-electrode material in a solution comprising lithium ions and an oxidizing agent, and after relithiating, separating the positive-electrode material from the solution.
FILED Friday, May 17, 2019
APPL NO 16/415879
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/54 (20130101) Original (OR) Class
H01M 10/0525 (20130101)
H01M 2004/028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11394085 Eskra et al.
FUNDED BY
Department of Defense (DOD)
Defense Logistics Agency (DLA)
Missile Defense Agency (MDA)
APPLICANT(S) Eskra Technical Products, Inc. (Saukville, Wisconsin)
ASSIGNEE(S) Eskra Technical Products, Inc. (Saukville, Wisconsin)
INVENTOR(S) Michael David Eskra (Saukville, Wisconsin);  Paula Margaret Ralston (Frederick, Maryland)
ABSTRACT A system and method for providing a ceramic-based separator onto an electrode is disclosed. A separator is formed on the electrode via a dry, solvent-free application of a ceramic-based separator to the electrode. An electrode is provided to an application area via a feed mechanism and a separator layer is then applied to the electrode that is comprised of a binder including at least one of a thermoplastic material and a thermoset material and an electrically non-conductive separator material, with the separator layer being applied to the electrode via a dry dispersion application.
FILED Monday, June 28, 2021
APPL NO 17/304862
ART UNIT 1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/052 (20130101)
H01M 50/46 (20210101) Original (OR) Class
H01M 50/403 (20210101)
H01M 50/446 (20210101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11394111 Khushrushahi
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Notch, Inc. (Cambridge, Massachusetts)
ASSIGNEE(S) Notch, Inc. (Cambridge, Massachusetts)
INVENTOR(S) Shahriar Khushrushahi (Cambridge, Massachusetts)
ABSTRACT A reconfigurable antenna systems includes a set of envelopes of active metamaterial panels, each envelope in the set being shaped to approximate a surface of at least partial revolution of a curve about an axis, wherein the surface defines a focal locus; a wideband antenna array disposed within the focal locus; and a controller, coupled to the panels, configured to activate each one of the panels, so as to control a property of each of the panels, the property selected from the group consisting of transmissivity, reflectivity, absorption, phase, polarization, bandwidth, angle sensitivity, resonant frequency, and combinations thereof.
FILED Friday, August 14, 2020
APPL NO 16/993732
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 1/425 (20130101) Original (OR) Class
H01Q 15/147 (20130101)
H01Q 15/148 (20130101)
H01Q 19/17 (20130101)
H01Q 19/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11394126 White et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Information Warfare Center Pacific (NIWCPACIFIC)
APPLICANT(S) HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S) HRL LABORATORIES, LLC (Malibu, California)
INVENTOR(S) Carson R. White (Agoura Hills, California);  Hyok J. Song (Oak Park, California);  Christopher P. Henry (Thousand Oaks, California)
ABSTRACT A distributed transmitter antenna includes a plurality of antenna segments and a plurality of transmitters. A first transmitter of the plurality of transmitters is coupled to a first antenna segment of the plurality of antenna segments, and a second transmitter of the plurality of transmitters is coupled to the first antenna segment and a second antenna segment of the plurality of antenna segments.
FILED Friday, July 24, 2020
APPL NO 16/938369
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 9/16 (20130101)
H01Q 9/30 (20130101)
H01Q 21/12 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11394471 Govoni et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) U.S. Army Combat Capabilities Development Command, Army Research Laboratory (Adelphi, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Mark A. Govoni (Abingdon, Maryland);  John T. Clark (Elkridge, Maryland)
ABSTRACT A method and apparatus for detecting RF power comprising an input port configured to receive a high-power RF signal, at least one diamond chip attenuator, coupled to the input port, configured to attenuate the high-power RF signal, and an RF detector integrated circuit, coupled to the at least one diamond chip attenuator, configured to convert the attenuated RF signal into an output indicium representing a power level of the high-powered RF signal.
FILED Wednesday, March 24, 2021
APPL NO 17/210552
ART UNIT 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 21/00 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 23/66 (20130101)
H01L 29/1602 (20130101)

Impedance Networks, e.g Resonant Circuits; Resonators
H03H 7/25 (20130101)

Transmission
H04B 17/101 (20150115) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 11389069 Grudic et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) Flashback Technologies, Inc. (Boulder, Colorado);  The Regents of the University of Colorado (Denver, Colorado)
ASSIGNEE(S) Flashback Technologies, Inc. (Westfield, New Jersey);  The Regents of the University of Colorado (Denver, Colorado)
INVENTOR(S) Gregory Zlatko Grudic (Niwot, Colorado);  Steven L. Moulton (Littleton, Colorado);  Isobel Jane Mulligan (Niwot, Colorado)
ABSTRACT Tools and techniques for estimating a probability that a patient is bleeding or has sustained intravascular volume loss (e.g., due to hemodialysis or dehydration) and/or to estimate a patient's current hemodynamic reserve index, track the patient's hemodynamic reserve index over time, and/or predict a patient's hemodynamic reserve index in the future. Tools and techniques for estimating and/or predicting a patient's dehydration state. Tools and techniques for controlling a hemodialysis machine based on the patient's estimated and/or predicted hemodynamic reserve index.
FILED Thursday, July 13, 2017
APPL NO 15/649411
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/021 (20130101)
A61B 5/029 (20130101)
A61B 5/318 (20210101)
A61B 5/02028 (20130101) Original (OR) Class
A61B 5/02042 (20130101)
A61B 5/7275 (20130101)
A61B 5/14551 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 40/60 (20180101)
G16H 50/30 (20180101)

Technologies for Adaptation to Climate Change
Y02A 90/10 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389083 Bansbach et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Heather Bansbach (Chesterfield, Virginia);  Timothy Crawford Sell (Pittsburgh, Pennsylvania)
ABSTRACT A neuromuscular, physiological, biomechanical, or musculoskeletal activity monitoring system for a subject is provided. The system includes a wearable inertial measurement unit including at least one accelerometer and/or at least one gyroscope. The system also includes a controller in communication with an output component. The controller is configured to: receive and process information from the inertial measurement unit representative of one or more physical actions performed by the subject; generate an inertial data set for the one or more physical actions based on the received and processed information; compare the generated inertial data set to reference data stored on computer readable memory in communication with the controller; and cause the output component to provide feedback including predictive injury information. The predictive injury information is based, at least in part, on the comparison between the generated data set and the reference data.
FILED Thursday, October 06, 2016
APPL NO 15/766165
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/22 (20130101)
A61B 5/45 (20130101)
A61B 5/486 (20130101)
A61B 5/743 (20130101)
A61B 5/744 (20130101)
A61B 5/1118 (20130101) Original (OR) Class
A61B 5/1121 (20130101)
A61B 5/6801 (20130101)
A61B 5/7435 (20130101)
A61B 2503/10 (20130101)
A61B 2505/09 (20130101)
A61B 2560/0223 (20130101)
A61B 2560/0462 (20130101)
A61B 2562/028 (20130101)
A61B 2562/0219 (20130101)
A61B 2562/0247 (20130101)

Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment
A63B 2220/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389395 Wrenn et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) DREXEL UNIVERSITY (Philadelphia, Pennsylvania)
ASSIGNEE(S) Drexel University (Philadelphia, Pennsylvania)
INVENTOR(S) Steven P. Wrenn (Swarthmore, Pennsylvania);  Stephen Dicker (Philadelphia, Pennsylvania)
ABSTRACT The present invention includes a construct that comprises at least one microbubble encapsulated within the aqueous core of a microcapsule. The present invention also includes a pharmaceutical composition comprising a construct comprising at least one microbubble encapsulated within the aqueous core of a microcapsule. The present invention further includes a method of imaging a tissue or organ in a subject, a method of delivering a therapeutic cargo to a tissue or organ in a subject, and a method of treating a disease or disorder in a subject.
FILED Friday, May 29, 2020
APPL NO 16/887974
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0009 (20130101) Original (OR) Class
A61K 9/1271 (20130101)
A61K 9/5031 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389788 Katz et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) Chevron U.S.A. Inc. (San Ramon, California);  The Regents of the University of California (Oakland, California)
ASSIGNEE(S) Chevron U.S.A. Inc. (San Ramon, California);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Alexander Katz (Richmond, California);  Alexander Okrut (Oakland, California);  Martina Aigner (Berkeley, California);  Xiaoying Ouyang (El Cerrito, California);  Stacey Ian Zones (San Francisco, California)
ABSTRACT Provided is a scalable delamination of a SSZ-70 framework zeolite, without the need for sonication, which has been previously made difficult by the charged nature of the imidazolium structure-directing agents that are required for zeolite synthesis. The method comprises contacting a B-SSZ-70 zeolite precursor with a zinc source such as zinc nitrate and a fluoride source.
FILED Thursday, February 14, 2019
APPL NO 16/275945
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 29/86 (20130101) Original (OR) Class
B01J 29/89 (20130101)
B01J 2229/22 (20130101)
B01J 2229/34 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 39/04 (20130101)
C01B 39/026 (20130101)
C01B 39/48 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/72 (20130101)
C01P 2002/86 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389800 Sperling et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Ralph Alexander Sperling (Eltville, Germany);  Adam R. Abate (San Francisco, California);  David A. Weitz (Bolton, Massachusetts)
ABSTRACT The present invention generally relates to systems and techniques for manipulating fluids and/or making droplets. In certain aspects, the present invention generally relates to droplet production. The droplets may be formed from fluids from different sources. In one set of embodiments, the present invention is directed to a microfluidic device comprising a plurality of droplet-making units, and/or other fluidic units, which may be substantially identical in some cases. Substantially each of the fluidic units may be in fluidic communication with a different source of a first fluid and a common source of a second fluid, in certain embodiments. In one aspect, substantially the same pressure may be applied to substantially all of the different sources of fluid, which may be used to cause fluid to move from the different sources into the microfluidic device. In some cases, the fluids may interact within the fluidic units, e.g., by reacting, or for the production of droplets within the microfluidic device. In some cases, the droplets may be used, for example, to form a library of droplets.
FILED Thursday, September 27, 2012
APPL NO 14/348113
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Mixing, e.g Dissolving, Emulsifying, Dispersing
B01F 23/41 (20220101)
B01F 33/3011 (20220101)
B01F 33/3021 (20220101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/0268 (20130101)
B01L 3/502784 (20130101) Original (OR) Class
B01L 2200/0673 (20130101)
B01L 2300/0816 (20130101)
B01L 2300/0867 (20130101)
B01L 2300/0883 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 137/212 (20150401)
Y10T 137/0391 (20150401)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389834 Horowitz et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) AMP Robotics Corporation (Louisville, Colorado)
ASSIGNEE(S) AMP Robotics Corporation (Louisville, Colorado)
INVENTOR(S) Matanya B. Horowitz (Golden, Colorado);  James A. Bailey (Boulder, Colorado);  John C. McCoy, Jr. (Thornton, Colorado)
ABSTRACT Systems and methods for sorting recyclable items and other materials are provided. In one embodiment, a system for sorting objects comprises: at least one imaging sensor; a controller comprising a processor and memory storage, wherein the controller receives image data captured by the image sensor; and at least one pusher device coupled to the controller, wherein the at least one pusher device is configured to receive an actuation signal from the controller. The processor is configured to detect objects travelling on a conveyor device and recognize at least one target item traveling on a conveyor device by processing the image data and to determine an expected time when the at least one target item will be located within a diversion path of the pusher device. The controller selectively generates the actuation signal based on whether a sensed object detected in the image data comprise the at least one target item.
FILED Friday, October 02, 2020
APPL NO 17/062383
ART UNIT 3653 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking
B07C 1/04 (20130101)
B07C 5/36 (20130101)
B07C 5/367 (20130101)
B07C 5/368 (20130101)
B07C 5/3422 (20130101) Original (OR) Class
B07C 2501/0054 (20130101)

Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 13/027 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389866 Rosi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Nathaniel L. Rosi (Pittsburgh, Pennsylvania);  Andrea David Merg (Pittsburgh, Pennsylvania);  Soumitra Punekar (Pittsburgh, Pennsylvania)
ABSTRACT Described herein are metal nanoparticle superstructures and methods and compounds for making the same.
FILED Thursday, December 14, 2017
APPL NO 15/842625
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/07 (20220101) Original (OR) Class
B22F 1/054 (20220101)
B22F 1/0553 (20220101)
B22F 9/24 (20130101)
B22F 2301/255 (20130101)

Nanostructures Formed by Manipulation of Individual Atoms, Molecules, or Limited Collections of Atoms or Molecules as Discrete Units; Manufacture or Treatment Thereof
B82B 3/0009 (20130101)
B82B 3/0066 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)
B82Y 40/00 (20130101)

Heterocyclic Compounds
C07D 249/04 (20130101)

Peptides
C07K 7/08 (20130101)
C07K 17/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11389902 Vadali et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Venkata Madhukanth Vadali (Madison, Wisconsin);  Chao Ma (Madison, Wisconsin);  Neil Arthur Duffie (Madison, Wisconsin);  Xiaochun Li (Madison, Wisconsin);  Frank Ewald Pfefferkorn (Madison, Wisconsin)
ABSTRACT Surface asperities, such as roughness characteristics, are reduced or otherwise mitigated via the control of surface regions including the asperities in different regimes. In accordance with various embodiments, the height of both high-frequency and low-frequency surface asperities is reduced by controlling characteristics of a surface region under a first regime to flow material from the surface asperities. A second regime is implemented to reduce a height of high-frequency surface asperities in the surface region by controlling characteristics of the surface region under a second regime to flow material that is predominantly from the high-frequency surface asperities, the controlled characteristics in the second regime being different than the controlled characteristics in the first regime. Such aspects may include, for example, controlling melt pools in each regime via energy pulses, to respectively mitigate/reduce the asperities.
FILED Monday, June 10, 2019
APPL NO 16/436228
ART UNIT 3761 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 26/354 (20151001) Original (OR) Class
B23K 26/3576 (20180801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390835 Sawyer et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Wallace Gregory Sawyer (Gainesville, Florida);  Thomas Ettor Angelini (Gainesville, Florida);  Steven Craig Ghivizzani (Gainesville, Florida);  Tapomoy Bhattacharjee (Gainesville, Florida);  Glyn Daniel Palmer (Gainesville, Florida)
ABSTRACT A three-dimensional cell growth medium is described. The cell growth medium may comprise hydrogel particles swollen with a liquid cell growth medium to form a granular gel yield stress material which undergoes a phase transformation from a solid phase to a liquid-like phase when an applied stress exceeds the yield stress. Cells may be placed in the three-dimensional cell growth medium according to any shape or geometry, and may remain in place within the three-dimensional cell growth medium.
FILED Saturday, May 07, 2016
APPL NO 15/571866
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 21/08 (20130101) Original (OR) Class
C12M 25/14 (20130101)
C12M 25/16 (20130101)
C12M 35/04 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0062 (20130101)
C12N 2513/00 (20130101)
C12N 2527/00 (20130101)
C12N 2533/30 (20130101)
C12N 2535/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390846 Ashton et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Randolph Scott Ashton (Madison, Wisconsin);  Carlos Ruben Marti-Figueroa (Madison, Wisconsin)
ABSTRACT Described herein are methods, compositions, and kits for forming engineered in vitro biomimetic, three-dimensional, tubular organoid structures by directed differentiation of human pluripotent stem cells within tubular channels formed in a hydrogel.
FILED Wednesday, October 16, 2019
APPL NO 16/654952
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0062 (20130101)
C12N 5/0618 (20130101) Original (OR) Class
C12N 2500/05 (20130101)
C12N 2500/32 (20130101)
C12N 2500/38 (20130101)
C12N 2501/33 (20130101)
C12N 2501/999 (20130101)
C12N 2506/02 (20130101)
C12N 2506/03 (20130101)
C12N 2506/45 (20130101)
C12N 2513/00 (20130101)
C12N 2533/18 (20130101)
C12N 2533/30 (20130101)
C12N 2533/74 (20130101)
C12N 2537/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11391563 Luo et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Qiaoen Luo (West Lafayette, Indiana);  Justin A. Patel (West Lafayette, Indiana);  Kevin J. Webb (West Lafayette, Indiana)
ABSTRACT An ultra-sensitive speckle-analyzing system is disclosed which includes an image capture device configured to receive a scattered field having a speckle configuration and thereby capture i) a reference speckle image, and ii) a subsequent speckle image, each of the reference and the subsequent speckle images having a plurality of speckles on a background; and a processor configured to generate a cross-correlation between the plurality of speckles of the reference and the subsequent speckle images, to thereby represent a change in the speckle configuration.
FILED Friday, January 15, 2021
APPL NO 17/150880
ART UNIT 2886 — Optics
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 11/2441 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11391729 Bergo
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) Adeptrix Corp. (Beverly, Massachusetts)
ASSIGNEE(S) ADEPTRIX CORP. (Beverly, Massachusetts)
INVENTOR(S) Vladislav B. Bergo (Boston, Massachusetts)
ABSTRACT Bead arrays suitable for analysis by mass spectrometry are disclosed. In an embodiment, a bead array includes multiple reactive sites, each of the reactive sites being capable of binding multiple distinct target analytes.
FILED Friday, September 07, 2018
APPL NO 16/125164
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/745 (20130101)
G01N 33/6845 (20130101)
G01N 33/6848 (20130101)
G01N 33/6854 (20130101)
G01N 33/54306 (20130101) Original (OR) Class
G01N 33/54313 (20130101)
G01N 2440/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11391734 Gopinath et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Ashwin Gopinath (Pasadena, California);  Paul W. K. Rothemund (Pasadena, California)
ABSTRACT Bistable devices are constructed using a polynucleotide platform for sensing molecular events such as binding or conformational changes of target molecules. Uses include measurement of target concentration, measuring the effect of environmental condition (such as heat, light, or pH) on the target, or screening a library for molecules that bind the target or modulate its biological function. Devices comprise three regions: a top lid, bottom lid, and flexible linker or hinge between them. A device has an open configuration in which the top and bottom lid are separated, and a closed configuration they are bound close together. Binding domains or variations of the target molecule are fixed to a device so that when the molecular event occurs, the device switches from open to closed, or vice versa, which generates a signal. Optimal device design is determined by the signal modality (optical or electronic) used to measure closure of surface-immobilized devices.
FILED Thursday, March 28, 2019
APPL NO 16/367240
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/11 (20130101)
C12N 2310/20 (20170501)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/47 (20130101)
G01N 21/553 (20130101)
G01N 21/6428 (20130101)
G01N 33/544 (20130101)
G01N 33/54373 (20130101) Original (OR) Class
G01N 2021/6439 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11391768 Rosenzweig et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) James Rosenzweig (Los Angeles, California);  Nathan Majernik (Los Angeles, California)
ABSTRACT An apparatus and method for in-situ determination of arc location within a radio-frequency (RF) waveguide. At least one pair of sound vibration transducers are coupled to positions within the waveguide from which data is collected. When a threshold level of voltage standing wave ratio (VSWR) is exceeded, then transducer data is processed to determine time-of-flight (TOF), to then compare data between transducers, to identify the faster longitudinal component with speed of sound in the material of the waveguide, from which longitudinal position information about the arc is generated.
FILED Tuesday, July 23, 2019
APPL NO 16/520303
ART UNIT 2863 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/1209 (20130101) Original (OR) Class
G01R 31/1272 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11391866 Barton, III et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Office of Emerging Frontiers and Multidisciplinary Activities (EFMA)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) David Russell Barton, III (Somerville, Massachusetts);  Mark Lawrence (Saint Louis, Missouri);  Jennifer A. Dionne (Menlo Park, California);  Jefferson Dixon (Staten Island, New York)
ABSTRACT High quality factor electromagnetic metasurfaces are provided. The metasurface is configured to have in plane guided-mode resonances (e.g., corresponding to waveguide modes or the like). Coupling features are included in the metasurface that are configured to couple free-space radiation to the guided mode resonances. The resulting structures have a high-Q response to free-space radiation and can be used for various applications, such as beam splitting, beam steering, and beam focusing or defocusing.
FILED Wednesday, November 04, 2020
APPL NO 17/089384
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 1/002 (20130101)
G02B 1/005 (20130101) Original (OR) Class
G02B 6/12 (20130101)
G02B 6/26 (20130101)
G02B 27/1086 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11392031 Stowers et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) Inpria Corporation (Corvallis, Oregon)
ASSIGNEE(S) Inpria Corporation (Corvallis, Oregon)
INVENTOR(S) Jason K. Stowers (Corvallis, Oregon);  Alan J. Telecky (Albany, Oregon);  Douglas A. Keszler (Corvallis, Oregon);  Andrew Grenville (Corvallis, Oregon)
ABSTRACT Stabilized precursor solutions can be used to form radiation inorganic coating materials. The precursor solutions generally comprise metal suboxide cations, peroxide-based ligands and polyatomic anions. Design of the precursor solutions can be performed to achieve a high level of stability of the precursor solutions. The resulting coating materials can be designed for patterning with a selected radiation, such as ultraviolet light, x-ray radiation or electron beam radiation. The radiation patterned coating material can have a high contrast with respect to material properties, such that development of a latent image can be successful to form lines with very low line-width roughness and adjacent structures with a very small pitch.
FILED Thursday, May 28, 2020
APPL NO 16/885581
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor;
G03F 7/20 (20130101)
G03F 7/0042 (20130101)
G03F 7/0043 (20130101) Original (OR) Class
G03F 7/327 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/24355 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11392644 Idreos et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S) Stratos Idreos (Cambridge, Massachusetts);  Niv Dayan (Somerville, Massachusetts);  Manoussos Gavriil Athanassoulis (Cambridge, Massachusetts)
ABSTRACT Embodiments of the invention utilize an improved LSM-tree-based key-value approach to strike the optimal balance between the costs of updates and lookups with any given main memory budget. The improved approach involves allocating memory to Bloom filters differently across different levels so as to minimize the sum of the false positive rates associated with the Bloom filters. In addition, the improved approach may predict the impact of the system design parameter(s) and/or environmental parameter(s) on the lookup performance. Subsequently, the improved approach may “self-tune” the system design parameter(s) and/or environment parameter(s) to maximize the throughput.
FILED Tuesday, January 09, 2018
APPL NO 16/433075
ART UNIT 2162 — Data Bases & File Management
CURRENT CPC
Electric Digital Data Processing
G06F 3/067 (20130101)
G06F 16/2246 (20190101)
G06F 16/9014 (20190101) Original (OR) Class
G06F 16/9535 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11392831 Sarioglu et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Ali Fatih Sarioglu (Atlanta, Georgia);  Ningquan Wang (Atlanta, Georgia)
ABSTRACT Systems and methods for decoding code-multiplexed Coulter signals are described herein. An example method can include receiving a code-multiplexed signal detected by a network of Coulter sensors, where the code-multiplexed signal includes a plurality of distinct Coulter signals, and inputting the code-multiplexed signal into a deep-learning network. The method can also include determining information indicative of at least one of a size, a speed, or a location of a particle detected by the network of Coulter sensors by using the deep-learning network to process the code-multiplexed signal. The method can further include storing the information indicative of at least one of the size, the speed, or the location of the particle detected by the network of Coulter sensors.
FILED Thursday, October 17, 2019
APPL NO 17/285561
ART UNIT 2886 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/12 (20130101)
G01N 15/1056 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/6257 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101) Original (OR) Class
G06N 3/0472 (20130101)
G06N 3/0481 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11393973 Ghatge et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S) Mayur Ghatge (Gainesville, Florida);  Glen H. Walters (Gainesville, Florida);  Toshikazu Nishida (Gainesville, Florida);  Roozbeh Tabrizian (Gainesville, Florida)
ABSTRACT A nano-mechanical acoustical resonator is designed and fabricated with CMOS compatible techniques to apply to mm-wave RF front-ends and 5G wireless communication systems which have extreme small scale and integrated in 3D sensors and actuators.
FILED Friday, November 22, 2019
APPL NO 16/692009
ART UNIT 2812 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/20 (20130101)
H01L 41/29 (20130101)
H01L 41/053 (20130101)
H01L 41/081 (20130101)
H01L 41/187 (20130101) Original (OR) Class
H01L 41/316 (20130101)
H01L 41/0477 (20130101)

Impedance Networks, e.g Resonant Circuits; Resonators
H03H 3/02 (20130101)
H03H 9/13 (20130101)
H03H 9/02031 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11394033 Yang et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
Materials Research Science and Engineering Centers (MRSECs)
APPLICANT(S) Cornell University (Ithaca, New York);  Wuhan University (Wuhan, China PRC)
ASSIGNEE(S) CORNELL UNIVERSITY (Ithaca, New York);  WUHAN UNIVERSITY (Wuhan, China PRC)
INVENTOR(S) Yao Yang (Ithaca, New York);  Héctor D. Abruña (Ithaca, New York);  Lin Zhuang (Wuhan, China PRC);  Hanging Peng (Wuhan, China PRC);  Li Xiao (Wuhan, China PRC)
ABSTRACT Provided is an apparatus containing, as a cathode catalyst, a metal oxide/carbon catalyst composition. The metal oxide/carbon catalyst composition includes 40 to 95 wt % porous Mn—Co spinel oxide nanoparticles of the formula MnxCo3-xO4. The nanoparticles have an octahedral morphology, an average particle size of 5-100 nm, and average pore sizes of 1-5 nm (where x is the atomic fraction of manganese and 3-x is the atomic fraction of cobalt). The metal oxide nanoparticles are supported on a carbon substrate that contains at least 96 atomic % carbon.
FILED Monday, March 16, 2020
APPL NO 16/819349
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/9033 (20130101) Original (OR) Class
H01M 4/9083 (20130101)
H01M 8/1004 (20130101)
H01M 8/1007 (20160201)
H01M 8/1009 (20130101)
H01M 8/1011 (20130101)
H01M 2004/8689 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11394062 Sloop
FUNDED BY
Department of Defense (DOD)
Defense Logistics Agency (DLA)
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) Hulico LLC (Bend, Oregon)
ASSIGNEE(S) HULICO LLC (Bend, Oregon)
INVENTOR(S) Steven E. Sloop (Bend, Oregon)
ABSTRACT Examples are disclosed of methods to recycle positive-electrode material of a lithium-ion battery. One example provides a method including relithiating the positive-electrode material in a solution comprising lithium ions and an oxidizing agent, and after relithiating, separating the positive-electrode material from the solution.
FILED Friday, May 17, 2019
APPL NO 16/415879
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/54 (20130101) Original (OR) Class
H01M 10/0525 (20130101)
H01M 2004/028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11394125 Sur et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) University of South Carolina (Columbia, South Carolina)
ASSIGNEE(S) University of South Carolina (Columbia, South Carolina)
INVENTOR(S) Sanjib Sur (Cayce, South Carolina);  Guoan Wang (Irmo, South Carolina);  Srihari Nelakuditi (Columbia, South Carolina)
ABSTRACT A reconfigurable antenna apparatus may include an antenna assembly and control circuitry. The antenna assembly may include an antenna patch array having a plurality of antenna patches and a switch array having plurality of switches. Each switch of the plurality switches may be electronically controllable to transition between states including a conducting state and a non-conducting state. Each switch may be electrically connected between two of the antenna patches of the antenna array. The control circuitry may be configured to control the states of the switches of the switch array to operate the antenna patch array in a first communications mode at a first wavelength, and control the states of the switches of the switch array to operate the antenna patch array in a second communications mode at a second wavelength.
FILED Friday, August 21, 2020
APPL NO 16/999391
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 1/38 (20130101)
H01Q 1/243 (20130101)
H01Q 9/0407 (20130101)
H01Q 21/065 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11394377 Carrigan
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Joseph T. Carrigan (Columbia, Maryland)
ABSTRACT An embodiment in accordance with the present invention provides a system and method of physically modulating a digital signal across a medium. A signal is sent one bit at a time (serially) as a period of high voltage followed by a period of low voltage. The present invention includes several major advantages. One advantage is that the code to execute the method is very lightweight. Another advantage is that the signals require no synchronization source. The signals of the present invention function as their own synchronization.
FILED Monday, February 20, 2017
APPL NO 15/999841
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Pulse Technique
H03K 3/017 (20130101)
H03K 5/04 (20130101)
H03K 7/06 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11394594 Pados et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) The Research Foundation for The State University of New York (Amherst, New York)
ASSIGNEE(S) The Research Foundation for The State University of New York (Amherst, New York)
INVENTOR(S) Dimitrios Pados (Amherst, New York);  Stella Batalama (Amherst, New York);  Georgios Skilvanitis (North Tonawanda, New York);  Song-Wen Huang (Amherst, New York)
ABSTRACT The present disclosure may be embodied as a transmitter for multiuser multicarrier-chirp-division-multiplexing (“MU-MCDM”) communications. The present disclosure may be embodied as a receive for MU-MCDM communications. The present disclosure may also be embodied as a method for transmitting an MU-MCDM communication signal. The present disclosure may also be embodied as a method for receiving an MU-MCDM communication signal.
FILED Monday, September 30, 2019
APPL NO 17/281146
ART UNIT 2632 — Digital Communications
CURRENT CPC
Transmission
H04B 1/7087 (20130101)
H04B 2001/6912 (20130101)

Multiplex Communication
H04J 13/0077 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 27/0014 (20130101)
H04L 27/264 (20130101) Original (OR) Class
H04L 27/2639 (20130101)
H04L 27/3405 (20130101)
H04L 27/26025 (20210101)
H04L 2027/0057 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 11389765 Roy et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Pratanu Roy (San Ramon, California);  Du Nguyen (Fremont, California);  Joshuah K. Stolaroff (Oakland, California)
ABSTRACT The present disclosure relates to a transport mechanism apparatus for transporting at least one of a gas or a fluid. The transport mechanism may have an inlet, an outlet and a triply periodic minimal surface (TPMS) structure. The TPMS structure is formed in a layer-by-layer three dimensional (3D) printing operation to include cells propagating in three dimensions, where the cells include wall portions having openings, and where the cells form a plurality of flow paths throughout the transport mechanism from the inlet to the outlet, and where the cells form the inlet and the outlet.
FILED Wednesday, January 09, 2019
APPL NO 16/243810
ART UNIT 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 53/02 (20130101)
B01D 53/228 (20130101) Original (OR) Class
B01D 67/0032 (20130101)
B01D 67/0041 (20130101)
B01D 71/022 (20130101)
B01D 71/70 (20130101)
B01D 2253/202 (20130101)
B01D 2253/342 (20130101)
B01D 2253/1122 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/28045 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 80/00 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390518 Black et al.
FUNDED BY
Department of Energy (DOE)
Brookhaven Science Associates, LLC (BSA)
Office of Science (DOE-SC)
Brookhaven National Laboratory (BNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Brookhaven Science Associates, LLC (BSA) at Upton, NY
APPLICANT(S) Brookhaven Science Associates LLC (Upton, New York)
ASSIGNEE(S) Brookhaven Science Associates, LLC (Upton, New York)
INVENTOR(S) Charles T. Black (New York, New York);  Atikur Rahman (Ridge, New York);  Matthew Eisaman (Port Jefferson, New York);  Ahsan Ashraf (Port Jefferson, New York)
ABSTRACT Technologies are described for methods and systems effective for etching nanostructures in a substrate. The methods may comprise depositing a patterned block copolymer on the substrate. The patterned block copolymer may include first and second polymer block domains. The methods may comprise applying a precursor to the patterned block copolymer to generate an infiltrated block copolymer. The precursor may infiltrate into the first polymer block domain and generate a material in the first polymer block domain. The methods may comprise applying a removal agent to the infiltrated block copolymer to generate a patterned material. The removal agent may be effective to remove the first and second polymer block domains from the substrate. The methods may comprise etching the substrate. The patterned material on the substrate may mask the substrate to pattern the etching. The etching may be performed under conditions to produce nanostructures in the substrate.
FILED Tuesday, December 08, 2020
APPL NO 17/114855
ART UNIT 1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems
B81C 1/00031 (20130101) Original (OR) Class
B81C 1/00111 (20130101)
B81C 2201/0132 (20130101)
B81C 2201/0149 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/118 (20130101)

Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor;
G03F 7/0002 (20130101)
G03F 7/405 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 2237/334 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/0271 (20130101)
H01L 21/0273 (20130101)
H01L 21/0337 (20130101)
H01L 21/3065 (20130101)
H01L 21/3086 (20130101)
H01L 31/02363 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11390533 van Hest et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  The Regents of the University of Colorado, a body corporate (Denver, Colorado)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  The Regents of the University of Colorado, a Body Corporate (Denver, Colorado)
INVENTOR(S) Marinus Franciscus Antonius Maria van Hest (Lakewood, Colorado);  David Todd Moore (Arvada, Colorado);  Benjia Dou (Cambridge, Massachusetts)
ABSTRACT The present disclosure relates to a composition that includes a perovskite crystal, where the perovskite crystal is in the form of a powder, and the perovskite crystal is semiconducting and photovoltaically active.
FILED Monday, December 16, 2019
APPL NO 16/715224
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals
C01F 17/30 (20200101) Original (OR) Class

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/34 (20130101)
C01P 2002/70 (20130101)
C01P 2002/82 (20130101)
C01P 2002/84 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11391223 Robel et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Caterpillar Inc. (Peoria, Illinois)
ASSIGNEE(S) Caterpillar Inc. (Peoria, Illinois)
INVENTOR(S) Wade James Robel (Dunlap, Illinois);  Spencer Landon Huhn (Chillicothe, Illinois);  Kevin Weiss (Peoria, Illinois);  John Robert McDonald (Peoria, Illinois);  Jason Kenneth Bloms (Edwards, Illinois)
ABSTRACT A controller may identify an indication to initiate an engine braking procedure associated with an engine of a machine. The controller may obtain, based on identifying the indication to initiate the engine braking procedure, information relating to a requested amount of engine braking power of the engine. The controller may cause one or more components of a variable geometry turbocharger (VGT) of the engine to adjust, and a throttle valve of the engine to adjust, based on the information relating to the requested amount of engine braking power of the engine.
FILED Wednesday, August 19, 2020
APPL NO 16/947826
ART UNIT 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Internal-combustion Piston Engines; Combustion Engines in General
F02B 37/24 (20130101)

Controlling Combustion Engines
F02D 9/02 (20130101) Original (OR) Class
F02D 41/0005 (20130101)
F02D 41/0007 (20130101)
F02D 41/1446 (20130101)
F02D 2009/0222 (20130101)
F02D 2009/0242 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11391567 Thorpe et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Bridger Photonics, Inc. (Bozeman, Montana)
ASSIGNEE(S) Bridger Photonics, Inc. (Bozeman, Montana)
INVENTOR(S) Michael Thorpe (Bozeman, Montana);  Aaron Kreitinger (Bozeman, Montana);  Stephen Crouch (Bozeman, Montana)
ABSTRACT Measurement approaches and data analysis methods are disclosed for combining 3D topographic data with spatially-registered gas concentration data to increase the efficiency of gas monitoring and leak detection tasks. Here, the metric for efficiency is defined as reducing the measurement time required to achieve the detection, or non-detection, of a gas leak with a desired confidence level. Methods are presented for localizing and quantifying detected gas leaks. Particular attention is paid to the combination of 3D spatial data with path-integrated gas concentration measurements acquired using remote gas sensing technologies, as this data can be used to determine the path-averaged gas concentration between the sensor and points in the measurement scene. Path-averaged gas concentration data is useful for finding and quantifying localized regions of elevated (or anomalous) gas concentration making it ideal for a variety of applications including: oil and gas pipeline monitoring, facility leak and emissions monitoring, and environmental monitoring.
FILED Monday, January 06, 2020
APPL NO 16/734769
ART UNIT 2853 — Printing/Measuring and Testing
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 21/20 (20130101) Original (OR) Class

Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 15/00 (20130101)

Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for
G01M 3/28 (20130101)
G01M 3/38 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/39 (20130101)
G01N 21/53 (20130101)
G01N 2021/1793 (20130101)
G01N 2021/1795 (20130101)

Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement
G01P 5/00 (20130101)

Image or Video Recognition or Understanding
G06V 20/64 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11391651 Kertesz et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Vilmos Kertesz (Oak Ridge, Tennessee);  Gary J. Van Berkel (Oak Ridge, Tennessee)
ABSTRACT A system and method for sampling a sample material includes a device for directing sample into a capture probe. The device for supplying sample material to the probe can be a device for radiating energy to the surface to eject sample from the sample material. A probe includes an outer probe housing having an open end. A liquid supply conduit has an outlet positioned to deliver liquid to the open end. An exhaust conduit removes liquid from the open end of the housing. The liquid supply conduit can be connectable to a liquid supply for delivering liquid at a first volumetric flow rate to the open end of the housing. A liquid exhaust system can be in fluid connection with the liquid exhaust conduit for removing liquid from the liquid exhaust conduit at a second volumetric flow rate such that gas with sample is withdrawn with the liquid.
FILED Monday, July 06, 2020
APPL NO 16/921733
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/10 (20130101)
G01N 1/24 (20130101) Original (OR) Class
G01N 2001/028 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 49/164 (20130101)
H01J 49/0418 (20130101)
H01J 49/0463 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11391671 Mallery et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) REBELLION PHOTONICS, INC. (Houston, Texas)
ASSIGNEE(S) REBELLION PHOTONICS, INC. (Houston, Texas)
INVENTOR(S) Ryan Mallery (Houston, Texas);  Ohad Israel Balila (Friendswood, Texas);  Robert Timothy Kester (Friendswood, Texas)
ABSTRACT An infrared (IR) imaging system for determining a concentration of a target species in an object is disclosed. The imaging system can include an optical system including a focal plane array (FPA) unit behind an optical window. The optical system can have components defining at least two optical channels thereof, said at least two optical channels being spatially and spectrally different from one another. Each of the at least two optical channels can be positioned to transfer IR radiation incident on the optical system towards the optical FPA. The system can include a processing unit containing a processor that can be configured to acquire multispectral optical data representing said target species from the IR radiation received at the optical FPA. One or more of the optical channels may be used in detecting objects on or near the optical window, to avoid false detections of said target species.
FILED Thursday, October 22, 2020
APPL NO 16/949255
ART UNIT 2884 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 5/0806 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/314 (20130101)
G01N 21/3504 (20130101) Original (OR) Class

Pictorial Communication, e.g Television
H04N 5/33 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11391866 Barton, III et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Office of Emerging Frontiers and Multidisciplinary Activities (EFMA)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) David Russell Barton, III (Somerville, Massachusetts);  Mark Lawrence (Saint Louis, Missouri);  Jennifer A. Dionne (Menlo Park, California);  Jefferson Dixon (Staten Island, New York)
ABSTRACT High quality factor electromagnetic metasurfaces are provided. The metasurface is configured to have in plane guided-mode resonances (e.g., corresponding to waveguide modes or the like). Coupling features are included in the metasurface that are configured to couple free-space radiation to the guided mode resonances. The resulting structures have a high-Q response to free-space radiation and can be used for various applications, such as beam splitting, beam steering, and beam focusing or defocusing.
FILED Wednesday, November 04, 2020
APPL NO 17/089384
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 1/002 (20130101)
G02B 1/005 (20130101) Original (OR) Class
G02B 6/12 (20130101)
G02B 6/26 (20130101)
G02B 27/1086 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11392782 Kan et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Cornell University (Ithaca, New York)
ASSIGNEE(S) CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S) Edwin C. Kan (Ithaca, New York);  Xiaonan Hui (Ithaca, New York)
ABSTRACT The present disclosure provides collaborative radiofrequency identification (RFID) readers that employ code division multiple access (CDMA) encoding to simultaneously broadcast to and read responses from tags in an overlapping reading zone with improved data synchronization and read yield rates. In some embodiments, a harmonic backscattering scheme is used to enable the system to have a much higher signal-to-noise ratio (SNR) and sensitivity, while the reader CDMA protocol can be integrated with an initial TDMA polling process or alternative tag CDMA scheme.
FILED Tuesday, May 14, 2019
APPL NO 17/055974
ART UNIT 2699 — Search and Capture Special Detail
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 7/10019 (20130101) Original (OR) Class
G06K 19/0724 (20130101)

Transmission
H04B 5/0031 (20130101)
H04B 5/0037 (20130101)
H04B 7/216 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11393652 Neubauer et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Muons, Inc. (Batavia, Illinois)
ASSIGNEE(S) Muons, Inc. (Batavia, Illinois)
INVENTOR(S) Michael L. Neubauer (San Francisco, California);  Alan J. Dudas (Alamo, California);  Stephen A. Kahn (Commack, New York)
ABSTRACT An anode structure for a magnetron provides for low eddy currents and efficient water cooling. The anode structure may be made by machining a bimetal blank including an out layer of a first metal and an inner layer of a second metal and formed by explosion bonding. The second metal has a resistivity lower than first metal and a thermal conductivity higher than the first metal. The machining may result in the anode structure with vanes each having a center (tip) portion made of the second metal and the rest made of the first metal. The machined anode structure may be coated with the second metal.
FILED Friday, January 24, 2020
APPL NO 16/752147
ART UNIT 2879 — Optics
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 9/02 (20130101)
H01J 23/02 (20130101) Original (OR) Class
H01J 25/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11393681 Mane et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Anil U. Mane (Naperville, Illinois);  Jeffrey W. Elam (Elmhurst, Illinois)
ABSTRACT Transition metal dichalcogenides (TMDs) are deposited by atomic layer deposition as thin layers on a substrate. The TMDs may be grown on oxide substrates and may have a tunable TMD-oxide interface. The TMD may be etched using an atomic layer etching technique.
FILED Wednesday, March 06, 2019
APPL NO 16/294797
ART UNIT 2894 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/0228 (20130101)
H01L 21/0262 (20130101)
H01L 21/02205 (20130101)
H01L 21/02255 (20130101)
H01L 21/02568 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11393976 Jarillo-Herrero et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Energy (DOE)
Office of Science (DOE-SC)
Ames Laboratory (AL)
Federally Funded Research and Development Center (FFRDC)
Operated by Iowa State University (IASTATE) at Ames, IA
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) Pablo Jarillo-Herrero (Cambridge, Massachusetts);  Qiong Ma (Cambridge, Massachusetts);  Nuh Gedik (Watertown, Massachusetts);  Suyang Xu (Cambridge, Massachusetts);  Zhiren Zheng (Cambridge, Massachusetts)
ABSTRACT An ultrathin, carbon-based memristor with a moiré superlattice potential shows prominent ferroelectric resistance switching. The memristor includes a bilayer material, such as Bernal-stacked bilayer graphene, encapsulated between two layers of a layered material, such as hexagonal boron nitride. At least one of the encapsulating layers is rotationally aligned with the bilayer to create the moiré superlattice potential. The memristor exhibits ultrafast and robust resistance switching between multiple resistance states at high temperatures. The memristor, which may be volatile or nonvolatile, may be suitable for neuromorphic computing.
FILED Tuesday, November 10, 2020
APPL NO 17/094141
ART UNIT 2827 — Semiconductors/Memory
CURRENT CPC
Static Stores
G11C 13/0069 (20130101)
G11C 2213/35 (20130101)
G11C 2213/53 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 45/10 (20130101) Original (OR) Class
H01L 45/142 (20130101)
H01L 45/143 (20130101)
H01L 45/148 (20130101)
H01L 45/149 (20130101)
H01L 45/1206 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11394020 Nanda et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-BATTELLE, LLC (Oakridge, Tennessee)
INVENTOR(S) Jagjit Nanda (Knoxville, Tennessee);  Ilias Belharouak (Knoxville, Tennessee);  Ethan C. Self (Oak Ridge, Tennessee);  Devendrasinh Udaisinh Darbar (Cookeville, Tennessee)
ABSTRACT A cathode for a lithium battery includes LiNi0.5-x/2Mn0.5-x/2MxO2 where M is at least one selected from the group consisting of Mo, Ti, Cr, Zr and V, and x is between 0.005-0.02. The LiNi0.5-x/2Mn0.5-x/2MxO2 can be coated with Mn2P2O7. The Mn2P2O7 can be 1-3 wt. %, based on the total weight of the LiNi0.5-x/2Mn0.5-x/2MxO2 and Mn2P2O7. A cathode composition, a lithium battery, and a method of making a lithium battery are also disclosed.
FILED Friday, June 21, 2019
APPL NO 16/448169
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/131 (20130101) Original (OR) Class
H01M 4/366 (20130101)
H01M 4/0404 (20130101)
H01M 4/505 (20130101)
H01M 4/525 (20130101)
H01M 4/625 (20130101)
H01M 4/1391 (20130101)
H01M 10/0525 (20130101)
H01M 2004/028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11394022 Xu et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UChicago Argonne, LLC (Chicago, Illinois)
ASSIGNEE(S) UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Guiliang Xu (Naperville, Illinois);  Xiang Liu (Darien, Illinois);  Khalil Amine (Oakbrook, Illinois)
ABSTRACT A [PxSbyMz]p/[carbon]q composite where x, y, and z represent atomic percentage values and are x>0; y>0; and z≥0, M is an electrically conductive metal, p and q represent the weight percentage values of the composite wherein p and q are in the range of 0-100%, and is p>0.
FILED Thursday, April 09, 2020
APPL NO 16/844485
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/364 (20130101) Original (OR) Class
H01M 4/587 (20130101)
H01M 4/623 (20130101)
H01M 10/054 (20130101)
H01M 10/0525 (20130101)
H01M 10/0569 (20130101)
H01M 50/46 (20210101)
H01M 2004/021 (20130101)
H01M 2300/0028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11394049 Tan et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) 24M Technologies, Inc. (Cambridge, Massachusetts)
ASSIGNEE(S) 24M Technologies, Inc. (Cambridge, Massachusetts)
INVENTOR(S) Taison Tan (Pasadena, California);  Yet-Ming Chiang (Weston, Massachusetts);  Naoki Ota (Lexington, Massachusetts);  Throop Wilder (Lincoln, Massachusetts);  Mihai Duduta (Somerville, Massachusetts)
ABSTRACT Embodiments described herein relate generally to devices, systems and methods of producing high energy density batteries having a semi-solid cathode that is thicker than the anode. An electrochemical cell can include a positive electrode current collector, a negative electrode current collector and an ion-permeable membrane disposed between the positive electrode current collector and the negative electrode current collector. The ion-permeable membrane is spaced a first distance from the positive electrode current collector and at least partially defines a positive electroactive zone. The ion-permeable membrane is spaced a second distance from the negative electrode current collector and at least partially defines a negative electroactive zone. The second distance is less than the first distance. A semi-solid cathode that includes a suspension of an active material and a conductive material in a non-aqueous liquid electrolyte is disposed in the positive electroactive zone, and an anode is disposed in the negative electroactive zone.
FILED Tuesday, February 23, 2021
APPL NO 17/182674
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/13 (20130101)
H01M 4/38 (20130101)
H01M 4/134 (20130101)
H01M 4/362 (20130101)
H01M 4/386 (20130101)
H01M 4/387 (20130101)
H01M 4/483 (20130101)
H01M 4/587 (20130101)
H01M 10/052 (20130101)
H01M 10/0525 (20130101) Original (OR) Class
H01M 2004/021 (20130101)
H01M 2004/023 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/10 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 70/50 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11394082 Frischmann et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Small Business Administration (SBA)
Small Business Technology Transfer (STTR)
APPLICANT(S) Sepion Technologies, Inc. (Oakland, California)
ASSIGNEE(S) Sepion Technologies, Inc. (Emerville, California)
INVENTOR(S) Peter David Frischmann (Oakland, California);  Brett Anthony Helms (Oakland, California);  Jon-Michael Alessandro (Oakland, California)
ABSTRACT Provided are electrochemical cells including separators permeable to some materials and impermeable to other materials in electrolytes. Also provide are methods of forming such separators. The selective permeability of a separator is achieved by its specific pore diameter and a narrow distribution of this diameter. Specifically, a species responsible for ion transport in an electrochemical cell are allowed to pass through the separator, while another species is blocked thereby preventing degradation of the cell. For example, a species containing lithium ions is allowed to pass in rechargeable cells, while one or more species containing transition metals are blocked. In some embodiments, a separator may include a membrane layer with at least 90% of pores of this having a diameter of between about 0.1 nanometers and 1.0 nanometer. The membrane layer may be a standalone layer or supported by a membrane support.
FILED Thursday, September 28, 2017
APPL NO 16/335219
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/0525 (20130101)
H01M 50/44 (20210101)
H01M 50/411 (20210101) Original (OR) Class
H01M 50/431 (20210101)
H01M 50/449 (20210101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11394091 Pozin et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) DURACELL U.S. OPERATIONS, INC. (Wilmington, Delaware);  NATIONAL TECHNOLOGY and ENGINEERING SOLUTIONS OF SANDIA, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) DURACELL U.S. OPERATIONS, INC. (Wilmington, Delaware);  NATIONAL TECHNOLOGY and ENGINEERING SOLUTIONS OF SANDIA, LLC (Albuquerque, New Mexico)
INVENTOR(S) Michael Pozin (Brookfield, Connecticut);  Walter Fred Paxton (Albuquerque, New Mexico);  Bryan James Kaehr (Albuquerque, New Mexico)
ABSTRACT A battery cell comprising a composite water-responsive safety layer and/or composite water- and pH-responsive safety layer to protect against tissue damage and/or electrolysis, when the battery cell is exposed to aqueous solution or tissue, is provided. The composite water-responsive safety layer and/or composite water- and pH-responsive safety layer is adapted to change from a non-electronically conducting state to an electronically conducting state.
FILED Tuesday, March 31, 2020
APPL NO 16/836745
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/0427 (20130101)
H01M 50/10 (20210101)
H01M 50/109 (20210101)
H01M 50/116 (20210101)
H01M 50/124 (20210101)
H01M 50/531 (20210101)
H01M 50/543 (20210101)
H01M 50/572 (20210101) Original (OR) Class
H01M 50/1245 (20210101)
H01M 2200/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 11390937 Manuel et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
John F. Kennedy Space Center (KSC)
NASA Shared Services Center (NSSC)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida);  United States Of America As Represented By The Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida);  UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
INVENTOR(S) Michele Viola Manuel (Gainesville, Florida);  Charles Robert Fisher (Fairfax, Virginia);  Maria Clara Wright (Orlando, Florida)
ABSTRACT Disclosed herein is a composite comprising a metal alloy matrix; where the metal alloy matrix comprises aluminum in an amount greater than 50 atomic percent; a first metal and a second metal; where the first metal is different from the second metal; and where the metal alloy matrix comprises a low temperature melting phase and a high temperature melting phase; where the low temperature melting phase melts at a temperature that is lower than the high temperature melting phase; and a contracting constituent; where the contracting constituent exerts a compressive force on the metal alloy matrix at a temperature between a melting point of the low temperature melting phase and a melting point of the high temperature melting phase or below the melting points of the high and low temperature melting phases.
FILED Tuesday, February 11, 2020
APPL NO 16/787823
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Casting of Metals; Casting of Other Substances by the Same Processes or Devices
B22D 19/00 (20130101)
B22D 21/007 (20130101)

Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/0003 (20130101)
B22F 2301/15 (20130101)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 15/20 (20130101)
B32B 2307/54 (20130101)

Alloys
C22C 1/0416 (20130101)
C22C 1/1036 (20130101)
C22C 1/1084 (20130101)
C22C 21/02 (20130101)
C22C 21/14 (20130101)
C22C 49/06 (20130101)
C22C 49/14 (20130101)

Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys
C22F 1/006 (20130101) Original (OR) Class
C22F 1/043 (20130101)
C22F 1/057 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11391356 Hu et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Ames Research Center (ARC)
APPLICANT(S) Sikorsky Aircraft Corporation (Stratford, Connecticut)
ASSIGNEE(S) Sikorsky Aircraft Corporation (Stratford, Connecticut)
INVENTOR(S) Wei Hu (Milford, Connecticut);  Shane Lewis (Honey Brook, Pennsylvania);  Bruce D. Hansen (Shelton, Connecticut);  Bryan Kenneth Baskin (Arlington, Texas)
ABSTRACT A hybrid gear includes a first portion having a plurality of first engagement features formed from a first material and having a first stiffness and a second portion having a plurality of second engagement features in intermeshing arrangement with the plurality of first engagement features. The plurality of second engagement features is formed from a second material distinct from the first material and having a second stiffness. The first stiffness of the plurality of first engagement features is within 20% of the second stiffness of the plurality of second engagement features.
FILED Wednesday, July 17, 2019
APPL NO 16/514213
ART UNIT 3658 — Material and Article Handling
CURRENT CPC
Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 35/00 (20130101)

Gearing
F16H 55/06 (20130101)
F16H 55/14 (20130101) Original (OR) Class
F16H 55/17 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11391493 Hasegawa et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) Mark M. Hasegawa (Highland, Maryland);  Kenneth O'Connor (Greenbelt, Maryland)
ABSTRACT A space-stable thin film composite coating is provided that exhibits high IR emittance properties similar to OSR mirrors, and which is thin enough to be applied to a flexible substrate. The composite coating can include hundreds of alternating layers of aluminum oxide and silicon dioxide vacuum deposited to individual layer thickness of about 150 Angstroms and 50 Angstroms, respectively. The composite coating can be attached to substrates having complex geometries, for example, at various points during integration and production of hardware. The thin film can increase thermal design efficiency, reduce radiator mass and costs, and reduce production time-frames by eliminating the complexity of OSR mirror bonding.
FILED Wednesday, September 19, 2018
APPL NO 16/135812
ART UNIT 1783 — Miscellaneous Articles, Stock Material
CURRENT CPC
Producing Particular Articles From Plastics or From Substances in a Plastic State
B29D 11/00865 (20130101)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 15/20 (20130101)

Solar Heat Collectors; Solar Heat Systems
F24S 23/82 (20180501) Original (OR) Class

Optical Elements, Systems, or Apparatus
G02B 1/12 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/24967 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11391672 Aslam et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) Shahid Aslam (Washington, District of Columbia);  Daniel P. Glavin (Greenbelt, Maryland);  Gerard T. Quilligan (Gulf Breeze, Florida);  Nicolas Gorius (Washington, District of Columbia);  Perry A. Gerakines (Greenbelt, Maryland);  John R. Kolasinski (Greenbelt, Maryland);  Dat Tran (Washington, District of Columbia);  Todd C. Purser (Greenbelt, Maryland)
ABSTRACT An apparatus for measuring vapor partial pressures of water and carbon dioxide includes a pair of infrared (IR) sources and a pair of quad filter detectors are placed opposite to one another such that the vapor partial pressures of water (H2O) and carbon dioxide (CO2) is measured and quantified in a short pathlength gas cell.
FILED Tuesday, August 25, 2020
APPL NO 17/002209
ART UNIT 2884 — Optics
CURRENT CPC
Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 11/02 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/2205 (20130101)
G01N 21/3504 (20130101)
G01N 21/3518 (20130101) Original (OR) Class
G01N 2201/0633 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11394168 Yu et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) Anthony Yu (Greenbelt, Maryland);  Kenji Numata (Greenbelt, Maryland)
ABSTRACT A master oscillator configured as a seed laser for a laser optical module includes a reduced size, temperature controlled non-planar ring oscillator, a piezo-electric transducer mounted on the non-planar ring oscillator, a pump laser diode, and coupling optics configured to couple a laser output of the pump laser diode to an end face of the non-planar ring oscillator. The pump laser diode may operate as a single-mode pump.
FILED Wednesday, June 05, 2019
APPL NO 16/432601
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/083 (20130101)
H01S 3/102 (20130101)
H01S 3/105 (20130101)
H01S 3/0606 (20130101)
H01S 3/0615 (20130101)
H01S 3/0617 (20130101)
H01S 3/0627 (20130101)
H01S 3/0941 (20130101)
H01S 3/1022 (20130101)
H01S 3/1028 (20130101) Original (OR) Class
H01S 3/1312 (20130101)
H01S 3/1611 (20130101)
H01S 3/1623 (20130101)
H01S 3/1643 (20130101)
H01S 3/1696 (20130101)
H01S 3/2308 (20130101)
H01S 3/2375 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 11392949 Boyd et al.
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S) The Government of the United States of America, as represented bv the Secretary of Homeland Security (Washington, District of Columbia)
INVENTOR(S) Daniel A. Boyd (Arlington, Virginia);  Kelli L. Biegger (McLean, Virginia);  Chang Ellison (Arlington, Virginia);  Jason Lim (Alexandria, Virginia)
ABSTRACT A method for verifying an identity of an individual as a first party via a first party system by a second party system comprises: sending a request for identification information of the first party; receiving first party information associated with a mobile identification credential (MIC) which the first party system received from an authorizing party system (APS) before the second party system sends the request for identification information of the first party to the first party system, the first party having consented to release the first party information to the second party system, and the first party information having been verified by the APS before the APS sends the MIC to the first party system; using the verified first party information associated with the MIC to verify or not verify an identity of the first party; verifying the identity of the first party before providing services to the first party.
FILED Friday, November 19, 2021
APPL NO 17/531194
ART UNIT 2887 — Optics
CURRENT CPC
Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 20/065 (20130101)
G06Q 20/409 (20130101)
G06Q 20/3827 (20130101)
G06Q 20/4014 (20130101) Original (OR) Class
G06Q 20/38215 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11392951 Boyd et al.
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
INVENTOR(S) Daniel Boyd (Arlington, Virginia);  Arun Vemury (North Bethesda, Maryland)
ABSTRACT Systems and methods and an example method including storing, in an access control memory of an access control computer system a set of access control identity records, receiving from an individual a proffered biographic information, and comparing the proffered biographic information to the access control identity records. In response to the comparing indicating a subset of than one access control identity records having biographic information having similarity to the proffered biographic information exceeding a threshold, generating and sending to a central resource computer system a biometric comparison request. The request includes the proffered biographic information of the persons, an indication of the biometric information of the person, and indication of biographic information in the identity records in the subset. A response is received from the central resource computer indicating whether a central resource identity record includes both a matching identity record biographic information and a matching identity record biometric information.
FILED Friday, September 17, 2021
APPL NO 17/478552
ART UNIT 3696 — Business Methods - Finance/Banking/ Insurance
CURRENT CPC
Electric Digital Data Processing
G06F 16/22 (20190101)
G06F 21/32 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 19/06037 (20130101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 20/40145 (20130101) Original (OR) Class
G06Q 50/265 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Non-Profit Organization (NPO) 

US 11392016 Grunwald et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
Non-Profit Organization (NPO)
Worcester Foundation for Biomedical Research (WFBR)
Worcester Foundation for Experimental Biology (WFEB)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) David Grunwald (Worcester, Massachusetts);  Maximiliaan Huisman (Brookfield, Massachusetts);  Carlas Smith (Delft, Netherlands)
ABSTRACT The described embodiments are directed to a system and methods of calibrating a fluorescence microscope and/or light detection device using a calibrating apparatus. The apparatus may comprise a main body housing, a sensor head, and a microcontroller assembly disposed within the housing. The housing may include an adapter to mechanically couple the housing to a microscope. The sensor head may comprise (i) an optical power sensor to produce a power signal representative of an optical power magnitude of light applied to the optical power sensor, (ii) an optical wavelength sensor configured to produce wavelength information associated with the light applied to the optical wavelength sensor, and (iii) a light source configured to direct light toward a detection device associated with the microscope. The microcontroller assembly may be configured to generate an optical power magnitude value based on the power signal and adjusted according to the wavelength information.
FILED Tuesday, October 13, 2020
APPL NO 17/069335
ART UNIT 2878 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 21/008 (20130101)
G02B 21/0032 (20130101)
G02B 21/361 (20130101)
G02B 21/362 (20130101)

Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor
G03B 21/204 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11393974 Agarwal et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
Non-Profit Organization (NPO)
Kentucky Science and Technology Corporation (KSTC)
U.S. State Government
Commonwealth of Kentucky
Kentucky Cabinet for Economic Development (KY-CED)
APPLICANT(S) Signal Solutions, LLC (Lexington, Kentucky)
ASSIGNEE(S) Signal Solutions, LLC (Lexington, Kentucky)
INVENTOR(S) Anuj Agarwal (Lexington, Kentucky);  Michael E. Lhamon (Lexington, Kentucky)
ABSTRACT Sensing an environment by confining a monitored live subject in an enclosure, detecting an effect on a coaxial piezoelectric cable resulting from the monitored live subject, wherein the coaxial piezoelectric cable is located at least proximate to the enclosure, and deriving information about a state of the monitored live subject based on the detected effect.
FILED Tuesday, October 13, 2020
APPL NO 17/069419
ART UNIT 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 29/005 (20130101)

Diagnosis; Surgery; Identification
A61B 5/113 (20130101)
A61B 5/0816 (20130101)
A61B 5/4812 (20130101)
A61B 5/4818 (20130101)
A61B 5/6888 (20130101)
A61B 5/6892 (20130101)
A61B 2503/40 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 41/45 (20130101) Original (OR) Class
H01L 41/087 (20130101)
H01L 41/193 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 11391562 Nguyen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
Naval Air Warfare Center Aircraft Division (NAWCAD)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) iSenseCloud, Inc. (San Jose, California)
ASSIGNEE(S) iSenseCloud, Inc. (Milpitas, California)
INVENTOR(S) An-Dien Nguyen (Fremont, California);  An H. Nguyen (Fremont, California)
ABSTRACT A fiber optic voltage conditioner, and method therefor, generally relate to voltage conditioning. In such a fiber optic voltage conditioner, there is a laser, and an optical circulator is coupled to receive a light signal from the laser. A controller is coupled to the laser and is configured to generate first control information for wavelength-drift control of the laser. A data acquisition module is coupled to the controller and is configured to generate second control information for the controller for adjustment of the first control information. A photodetector is coupled to the optical circulator to receive a returned optical signal and is coupled to the data acquisition module to provide an analog output signal thereto. The photodetector is configured to generate the analog output signal responsive to the returned optical signal. The data acquisition module is configured to generate the second control information using the analog output signal.
FILED Thursday, February 20, 2020
APPL NO 16/796447
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 11/165 (20130101) Original (OR) Class

Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for
G01K 11/3206 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 5/0612 (20130101)
H01S 5/0617 (20130101)
H01S 5/0622 (20130101)
H01S 5/0687 (20130101)
H01S 5/02415 (20130101)
H01S 5/4087 (20130101)
H01S 5/06804 (20130101)
H01S 5/06808 (20130101)
H01S 5/06837 (20130101)

Transmission
H04B 10/572 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11394082 Frischmann et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Small Business Administration (SBA)
Small Business Technology Transfer (STTR)
APPLICANT(S) Sepion Technologies, Inc. (Oakland, California)
ASSIGNEE(S) Sepion Technologies, Inc. (Emerville, California)
INVENTOR(S) Peter David Frischmann (Oakland, California);  Brett Anthony Helms (Oakland, California);  Jon-Michael Alessandro (Oakland, California)
ABSTRACT Provided are electrochemical cells including separators permeable to some materials and impermeable to other materials in electrolytes. Also provide are methods of forming such separators. The selective permeability of a separator is achieved by its specific pore diameter and a narrow distribution of this diameter. Specifically, a species responsible for ion transport in an electrochemical cell are allowed to pass through the separator, while another species is blocked thereby preventing degradation of the cell. For example, a species containing lithium ions is allowed to pass in rechargeable cells, while one or more species containing transition metals are blocked. In some embodiments, a separator may include a membrane layer with at least 90% of pores of this having a diameter of between about 0.1 nanometers and 1.0 nanometer. The membrane layer may be a standalone layer or supported by a membrane support.
FILED Thursday, September 28, 2017
APPL NO 16/335219
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/0525 (20130101)
H01M 50/44 (20210101)
H01M 50/411 (20210101) Original (OR) Class
H01M 50/431 (20210101)
H01M 50/449 (20210101)
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 11390473 Perry-Eaton et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Wayne R. Perry-Eaton (Leesburg, Virginia);  George W. Potts, Jr. (Upper Marlboro, Maryland);  Daniel Radtke (Madison, Wisconsin)
ABSTRACT An automated system for transferring articles from a container. An item transfer system includes a frame configured to receive a first tray and a second tray, a movable paddle assembly, a frame, and a plurality of actuators. The system is configured to transfer articles from the first tray to the second tray by an automated process including securing the articles within the first tray with the paddle assembly, moving a lifting assembly or an item support platform such that the articles are in a slidable configuration relative to the first tray, moving the paddle assembly and/or the item support platform in one or more linear translations to remove the items from the first tray and place the items above the second tray, and releasing the items into the second tray.
FILED Friday, May 08, 2020
APPL NO 16/870605
ART UNIT 3653 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking
B07C 3/008 (20130101)

Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors
B65G 65/04 (20130101) Original (OR) Class
B65G 65/38 (20130101)
B65G 2207/46 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11392141 Dinh
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Han Truong Dinh (Falls Church, Virginia)
ABSTRACT Systems and methods for coordinating container transportation. A method of autonomously transporting a cargo container includes aligning a distribution vehicle with the cargo container. The distribution vehicle is aligned with and hitched to the cargo container. An attachment can be connected to the cargo container for mating systems of the cargo container with the distribution vehicle. A system has inputs for vehicle and container location, arrival and departure times, facility plans, and can coordinate the autonomous movement of containers in a facility or a yard.
FILED Friday, January 17, 2020
APPL NO 16/746606
ART UNIT 3666 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Arrangements of Heating, Cooling, Ventilating or Other Air-treating Devices Specially Adapted for Passenger or Goods Spaces of Vehicles
B60H 1/00507 (20130101)

Systems for Controlling or Regulating Non-electric Variables
G05D 1/104 (20130101)
G05D 1/0297 (20130101) Original (OR) Class

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/0832 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 11390653 Tullman et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland)
ASSIGNEE(S) GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland)
INVENTOR(S) Jennifer A. Tullman (Germantown, Maryland);  Zvi Kelman (Gaithersburg, Maryland);  John P. Marino (Silver Spring, Maryland)
ABSTRACT An amino acid-specific binder selectively binds to a binding amino acid. A binder complex selectively identifies the binding amino acid and includes an adjunct attached to the amino acid-specific binder. The adjunct includes a taggant, protein, substrate, or chemical modifier. Selectively identifying an N-terminal amino acid includes anchoring a C-terminal end; contacting an N-terminal amino acid of the anchored analyte with the binder complex; selectively binding when the N-terminal amino acid includes the binding amino acid; producing, by the taggant of the tagged complex, a taggant signal; detecting the taggant signal; and identifying the N-terminal amino acid based on the taggant signal.
FILED Thursday, August 06, 2020
APPL NO 16/986334
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 1/13 (20130101)
C07K 14/195 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/582 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of State (DOS) 

US 11390886 Jin et al.
FUNDED BY
Department of State (DOS)
Bureau of Educational and Cultural Affairs (ECA)
Fulbright Program (FULBRIGHT)
Fulbright Foreign Student Program (FFSP)
APPLICANT(S) Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
ASSIGNEE(S) RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey)
INVENTOR(S) Shengkan Jin (Belle Mead, New Jersey);  Juan-Carlos Collantes (Princeton, New Jersey)
ABSTRACT The present invention discloses a system for targeted gene editing and related uses.
FILED Friday, July 15, 2016
APPL NO 15/744505
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/11 (20130101)
C12N 15/102 (20130101)
C12N 15/902 (20130101) Original (OR) Class
C12N 2310/20 (20170501)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 11391288 Miller et al.
FUNDED BY
Department of Transportation (USDOT)
Federal Aviation Administration (FAA)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Kyle Louis Miller (Cincinnati, Ohio);  Andrew Breeze-Stringfellow (Montgomery, Ohio)
ABSTRACT A turbo machine, a computer-implemented method, and a computer system for operating a compressor assembly are provided. The method includes comparing a first data set and a second data set to determine a first correlation factor, comparing the first correlation factor to a first threshold that at least partially determines whether a stall precursor exists, removing mean values from the first data set and the second data set, comparing the first data set and the second data set each removed of mean values to determine a second correlation factor, and comparing the second correlation factor to the first threshold, and classifying the stall precursor as either a spike stall precursor, a modal stall precursor, or a combination stall precursor.
FILED Wednesday, September 09, 2020
APPL NO 17/015400
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive-displacement Pumps
F04D 27/001 (20130101) Original (OR) Class
F04D 27/02 (20130101)

Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G
F05B 2220/302 (20130101)
F05B 2270/301 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2270/101 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Environmental Protection Agency (EPA) 

US 11390540 Viswanathan
FUNDED BY
Environmental Protection Agency (EPA)
EPA Office for Research and Development (EPA-ORD)
APPLICANT(S) BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas)
ASSIGNEE(S) BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas)
INVENTOR(S) Tito Viswanathan (Little Rock, Arkansas)
ABSTRACT The present disclosure relates to water purification compositions and the method of producing the same. Specifically, the present disclosure relates to a method of producing a water purification composition including providing a substrate having one or more functional groups that has hydroxyl, thiol, carboxyl, and/or amino group; depositing a solution of a metal salt on the substrate; depositing a solution of carboxylic acid compound on the substrate; forming a mixture wherein the metal cross-links the hydroxyl, thiol, carboxyl and/or amino groups on the surface of the substrate, and the carboxylic acid compound; and heating the mixture till the product is dry.
FILED Tuesday, July 28, 2020
APPL NO 16/940496
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/0203 (20130101)
B01J 41/09 (20170101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/42 (20130101) Original (OR) Class
C02F 1/281 (20130101)
C02F 1/288 (20130101)
C02F 2001/422 (20130101)
C02F 2101/14 (20130101)
C02F 2101/20 (20130101)
C02F 2101/103 (20130101)
C02F 2101/105 (20130101)
C02F 2101/106 (20130101)
C02F 2103/001 (20130101)
C02F 2103/10 (20130101)
C02F 2305/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. State Government 

US 11393974 Agarwal et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
Non-Profit Organization (NPO)
Kentucky Science and Technology Corporation (KSTC)
U.S. State Government
Commonwealth of Kentucky
Kentucky Cabinet for Economic Development (KY-CED)
APPLICANT(S) Signal Solutions, LLC (Lexington, Kentucky)
ASSIGNEE(S) Signal Solutions, LLC (Lexington, Kentucky)
INVENTOR(S) Anuj Agarwal (Lexington, Kentucky);  Michael E. Lhamon (Lexington, Kentucky)
ABSTRACT Sensing an environment by confining a monitored live subject in an enclosure, detecting an effect on a coaxial piezoelectric cable resulting from the monitored live subject, wherein the coaxial piezoelectric cable is located at least proximate to the enclosure, and deriving information about a state of the monitored live subject based on the detected effect.
FILED Tuesday, October 13, 2020
APPL NO 17/069419
ART UNIT 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 29/005 (20130101)

Diagnosis; Surgery; Identification
A61B 5/113 (20130101)
A61B 5/0816 (20130101)
A61B 5/4812 (20130101)
A61B 5/4818 (20130101)
A61B 5/6888 (20130101)
A61B 5/6892 (20130101)
A61B 2503/40 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 41/45 (20130101) Original (OR) Class
H01L 41/087 (20130101)
H01L 41/193 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 11394588 Robinson
FUNDED BY
APPLICANT(S) Rampart Communications, Inc. (Annapolis, Maryland)
ASSIGNEE(S) Rampart Communications, Inc. (Annapolis, Maryland)
INVENTOR(S) Matthew Brandon Robinson (Crownsville, Maryland)
ABSTRACT A system includes first and second sets of communication devices. A processor coupled to the first set of communication devices produces a first encoded vector and transmits the first encoded vector to the second set of communication devices via a communication channel that applies a channel transformation to the first encoded vector during transmission. A processor coupled to the second set of communication devices receives the transformed signal, detects an effective channel thereof, and identifies left and right singular vectors of the effective channel. A precoding matrix is selected from a codebook of unitary matrices based on a message, and a second encoded vector is produced based on a second known vector, the precoding matrix, a complex conjugate of the left singular vectors, and the right singular vectors. The second encoded vector is sent to the first set of communication devices for identification of the message.
FILED Thursday, January 28, 2021
APPL NO 17/161118
ART UNIT 2633 — Digital Communications
CURRENT CPC
Transmission
H04B 7/0413 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 25/0391 (20130101) Original (OR) Class
H04L 27/2602 (20130101)

Wireless Communication Networks
H04W 12/03 (20210101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11394727 Payton
FUNDED BY
APPLICANT(S) HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S) HRL LABORATORIES, LLC (Malibu, California)
INVENTOR(S) David W. Payton (Calabasas, California)
ABSTRACT Described is a system for side-channel based detection of cyber-attack. In operation, the system converts data bus signals from a platform (e.g., vehicular platform) into a first time series of system states. The system further converts analog side-channel signals from the platform into a second time-series of system states. Anomalous behavior of the platform is detected by comparing the first time series of system states with the second time series of system states to identify violations of predetermined constraints. Upon detection, the anomalous behavior is designated as a cyber-attack of the platform, which causes the platform to initiate an action based on the detected cyber-attack. Such actions include implementing a safe made, etc.
FILED Thursday, December 13, 2018
APPL NO 16/219749
ART UNIT 2497 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/85 (20130101)
G06F 21/755 (20170801)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 12/40 (20130101)
H04L 63/1416 (20130101) Original (OR) Class
H04L 63/1425 (20130101)
H04L 63/1441 (20130101)
H04L 67/12 (20130101)
H04L 69/08 (20130101)
H04L 2012/40215 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, July 19, 2022.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20220719.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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