FedInvent™ Patents
Patent Details for Tuesday, August 09, 2022
This page was updated on Thursday, August 11, 2022 at 11:01 PM GMT
Department of Health and Human Services (HHS)
| US 11406122 | Longo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| INVENTOR(S) | Valter D. Longo (Playa del Rey, California); In Young Choi (Garden Grove, California) |
| ABSTRACT | A method for alleviating a symptom of multiple sclerosis or other autoimmune or inflammatory disease includes a step of identifying a subject having multiple sclerosis or other autoimmune diseases. A fasting mimicking diet is administered to the subject for a first predetermined time period, the fasting mimicking diet providing less than 50% of the subject's normal caloric intake. A non-fasting diet is administered to the subject for a second time period following the first time period. The non-fasting diet provides the subject greater than 60 percent of the subject's normal caloric intake but a calorie intake necessary for the subject to return to a normal healthy weight. |
| FILED | Thursday, April 02, 2015 |
| APPL NO | 15/301480 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/30 (20160801) Original (OR) Class Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 45/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) G01N 2800/285 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406258 | Larin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| INVENTOR(S) | Kirill V. Larin (Friendswood, Texas); Achuth Nair (Houston, Texas); Manmohan Singh (Houston, Texas); Salavat Aglyamov (Friendswood, Texas) |
| ABSTRACT | A system and method for measuring biomechanical properties of tissues without external excitation are capable of measuring and quantifying these parameters of tissues in situ and in vivo. The system and method preferably utilize a phase-sensitive optical coherence tomography (OCT) system for measuring the displacement caused by the intrinsic heartbeat. The method allows noninvasive and nondestructive quantification of tissue mechanical properties. Preferably, the method is used to detect tissue stiffness and to evaluate its stiffness due to intrinsic pulsatile motion from the heartbeat. This noninvasive method can evaluate the biomechanical properties of the tissues in vivo for detecting the onset and progression of degenerative or other diseases and evaluating the efficacy of therapies. |
| FILED | Monday, June 22, 2020 |
| APPL NO | 16/907424 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/16 (20130101) A61B 3/0025 (20130101) Original (OR) Class A61B 3/102 (20130101) A61B 3/165 (20130101) A61B 5/0051 (20130101) A61B 5/0053 (20130101) A61B 5/0066 (20130101) A61B 5/0093 (20130101) A61B 5/0097 (20130101) A61B 8/10 (20130101) A61B 8/485 (20130101) A61B 2576/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406277 | Riederer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Stephen J. Riederer (Rochester, Minnesota); Eric G. Stinson (Rochester, Minnesota) |
| ABSTRACT | The present disclosure provides systems and methods for measuring a concentration of a contrast agent using magnetic resonance imaging (MRI). The method includes acquiring pre- and post-contrast data from a volume of a subject, where the pre-contrast data is acquired before a contrast agent is administered and the post-contrast data is acquired after the contrast agent is administered. Pre- and post-contrast resonance frequency maps are then computed, where the pre-contrast frequency map is based on one or more pre-contrast resonance frequency values, and the post-contrast resonance frequency map is based on one or more post-contrast resonance frequency values. The pre- and post-contrast frequency maps are then used to generate a resonance frequency change map that is subsequently used to generate a contrast agent concentration map that indicates a concentration of the contrast agent that was present at each voxel in the volume at the second time. |
| FILED | Thursday, April 19, 2018 |
| APPL NO | 16/606140 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/485 (20130101) G01R 33/4828 (20130101) G01R 33/5601 (20130101) G01R 33/5608 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406290 | Chapman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| INVENTOR(S) | Ryan Chapman (North Hartland, Vermont); Douglas Wayne Van Citters (Hanover, New Hampshire); Wayne Edward Moschetti (Hanover, New Hampshire); John-Erik Bell (Hanover, New Hampshire) |
| ABSTRACT | Systems and methods for monitoring a range of motion of a joint are described. For example, in one embodiment, a first set of sensors may sense accelerations of a first body portion located on a first side of the joint and a second set of sensors may sense accelerations of the second body portion located on a second opposing side of the joint. The acceleration data may then be used to compute the relative motion of the first and second body portions to determine movement of the joint. This joint movement may then be used to determine one or more range of motion movement metrics which are output for viewing by a subject or medical practitioner. |
| FILED | Tuesday, October 08, 2019 |
| APPL NO | 16/596123 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0022 (20130101) A61B 5/0024 (20130101) A61B 5/112 (20130101) A61B 5/486 (20130101) A61B 5/1071 (20130101) A61B 5/1118 (20130101) A61B 5/1121 (20130101) Original (OR) Class A61B 5/4528 (20130101) A61B 5/4566 (20130101) A61B 5/4571 (20130101) A61B 5/4576 (20130101) A61B 5/4585 (20130101) A61B 5/6804 (20130101) A61B 5/6823 (20130101) A61B 5/6824 (20130101) A61B 5/6828 (20130101) A61B 5/6831 (20130101) A61B 5/6832 (20130101) A61B 5/7275 (20130101) A61B 5/7475 (20130101) A61B 2505/07 (20130101) A61B 2505/09 (20130101) A61B 2560/0209 (20130101) A61B 2560/0214 (20130101) A61B 2562/04 (20130101) A61B 2562/0219 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406322 | Lieber et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | REHABILITATION INSTITUTE OF CHICAGO (Chicago, Illinois) |
| ASSIGNEE(S) | REHABILITATION INSTITUTE OF CHICAGO (Chicago, Illinois) |
| INVENTOR(S) | Richard L. Lieber (Chicago, Illinois); Stojan Radic (San Diego, California); Kevin Young (San Diego, California) |
| ABSTRACT | Methods and systems for measuring muscle sarcomere length are disclosed. In an embodiment, a method comprises illuminating a set of muscle fibers with electromagnetic radiation, measuring an intensity of the electromagnetic radiation as reflected from the muscle fibers, the measuring occurring as a function of wavelength, determining wavelengths corresponding to maximums of reflected intensity, and correlating the determined wavelengths with respective muscle sarcomere lengths. In an embodiment, a system comprises an illumination source system for illuminating the set of muscle fibers with electromagnetic radiation, and an analyzer for measuring the intensity of the electromagnetic radiation as reflected from the muscle fibers. |
| FILED | Friday, September 27, 2019 |
| APPL NO | 16/585648 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0075 (20130101) A61B 5/0084 (20130101) A61B 5/1076 (20130101) A61B 5/1079 (20130101) A61B 5/4519 (20130101) Original (OR) Class A61B 2505/05 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406361 | Hofstetter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Siemens Healthcare GmbH (Erlangen, Germany); University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | Siemens Healthcare GmbH (Erlangen, Germany); University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Lorne Hofstetter (Salt Lake City, Utah); Bradley Drake Bolster, Jr. (Sandy, Utah); Dennis L. Parker (Centerville, Utah); Henrik Odeen (Salt Lake City, Utah); Allison Payne (Salt Lake City, Utah) |
| ABSTRACT | A method for mapping shear wave velocity in biological tissues includes using an ultrasound transducer to generate mechanical excitations at a plurality of locations in a region of interest. An MRI system is used to capture a phase image of each mechanical excitation, wherein motion encoding gradients (MEGs) of the MRI system encode a propagating shear wavefront caused by the mechanical excitation. A plurality of shear wave velocity maps is generated based on the phase images, wherein each shear wave velocity map depicts velocity between adjacent propagating shear wavefronts. The shear wave speed values are combined to generate a composite shear wave velocity map of the region of interest. |
| FILED | Monday, June 17, 2019 |
| APPL NO | 16/442628 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0048 (20130101) A61B 8/485 (20130101) Original (OR) Class A61B 8/5223 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/52042 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406401 | Szafron et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California); The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California); The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | Jason Szafron (Hamden, Connecticut); Duncan Maitland (College Station, Texas); Ward Small, IV (Livermore, California); Patrick R. Buckley (Livermore, California); Andrea D. Muschenborn (Bloomington, Indiana) |
| ABSTRACT | An embolectomy device comprised of an expansion unit and a support unit is disclosed. The expansion unit can be actuated in response to one or more external stimuli, and the support unit, located proximately to the expansion unit, provides a force to hold the expansion unit in place and to further induce the expansion unit's radial expansion. The radial expansion of the expansion unit causes the expansion unit to physically contact a blood clot, enabling the blood clot to be removed. In some embodiments, the expansion unit can be fabricated from a shape memory polymer foam. In some embodiments the support unit can be fabricated from any elastic material including, without limitation, shape memory alloys. |
| FILED | Tuesday, December 03, 2019 |
| APPL NO | 16/701417 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/22 (20130101) Original (OR) Class A61B 2017/00526 (20130101) A61B 2017/00867 (20130101) A61B 2017/00871 (20130101) A61B 2017/2212 (20130101) A61B 2017/22094 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406485 | Hetts et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Steven W. Hetts (Hillsborough, California); Anand S. Patel (San Francisco, California); Mark W. Wilson (San Francisco, California) |
| ABSTRACT | In vivo positionable filtration devices are provided that filter one or more therapeutic agents in blood flowing in a blood vessel. The filtration devices include an elongated member and a filtering component coupled to the elongated member. The elongated member and the filtering component are dimensioned for positioning within the blood vessel of a human or non-human animal. Further, the filtering component includes a filtration material to filter the one or more therapeutic agents from the blood. Methods of in vivo filtration of the one or more therapeutic agents are also provided. The methods include positioning a filtration device in the blood vessel of a body of the human or non-human animal, and administering a therapeutic agent upstream from a target tissue site to direct flow of the therapeutic agent to the target tissue site and then to the filtration device. The filtration device is positioned downstream from the target tissue site. |
| FILED | Wednesday, December 18, 2013 |
| APPL NO | 14/649838 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/011 (20200501) A61F 2/013 (20130101) Original (OR) Class A61F 2/0105 (20200501) A61F 2/0108 (20200501) A61F 2002/015 (20130101) A61F 2230/0067 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/3615 (20140204) A61M 1/3679 (20130101) A61M 25/0029 (20130101) A61M 2025/1052 (20130101) A61M 2025/1097 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406603 | Bayley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Oxford University Innovation Limited (Oxford, United Kingdom) |
| ASSIGNEE(S) | Oxford University Innovation Limited (Oxford, United Kingdom) |
| INVENTOR(S) | John Hagan Pryce Bayley (Oxford, United Kingdom); Andrew Heron (Oxford, United Kingdom); Gabriel Villar (Oxford, United Kingdom) |
| ABSTRACT | The invention provides a droplet encapsulate comprising: a drop of a hydrophobic medium; a peripheral layer of non-polymeric amphipathic molecules around the surface of the drop; and an aqueous droplet within the peripheral layer, the aqueous droplet comprising: (a) an aqueous medium and (b) an outer layer of non-polymeric amphipathic molecules around the surface of the aqueous medium. The invention also provides processes for preparing the droplet encapsulates. Various uses of the droplet encapsulates are also described, including their use as drug delivery vehicles, in synthetic biology, and in the study of membrane proteins. |
| FILED | Thursday, December 19, 2019 |
| APPL NO | 16/721302 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/50 (20130101) Original (OR) Class A61K 9/113 (20130101) A61K 9/1075 (20130101) A61K 9/1271 (20130101) A61K 31/085 (20130101) A61K 49/0002 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/02 (20130101) B01J 13/025 (20130101) Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 67/0097 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2984 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
11406637 — Carbonic anhydrase enzymes for regulating mast cell hematopoiesis and type 2 inflammation
| US 11406637 | Siracusa |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rutgers, the State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| INVENTOR(S) | Mark C. Siracusa (New Brunswick, New Jersey) |
| ABSTRACT | The invention provides methods and compositions that are useful for treating allergic diseases, bacterial infections, fungal infections, viral infections, mastocytosis, mast cell-mediated inflammation and parasite infections (e.g., helminth infections). |
| FILED | Tuesday, July 28, 2020 |
| APPL NO | 16/940677 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/18 (20130101) A61K 31/423 (20130101) A61K 31/423 (20130101) A61K 31/433 (20130101) A61K 31/433 (20130101) A61K 31/451 (20130101) A61K 31/451 (20130101) A61K 31/505 (20130101) A61K 31/505 (20130101) A61K 31/513 (20130101) Original (OR) Class A61K 31/513 (20130101) A61K 31/542 (20130101) A61K 31/542 (20130101) A61K 31/4184 (20130101) A61K 31/4184 (20130101) A61K 31/7048 (20130101) A61K 31/7048 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406643 | Yu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Dihua Yu (Houston, Texas); Frank Lowery (Houston, Texas); Chenyu Zhang (Houston, Texas); Sunil Acharya (Houston, Texas); Ping Li (Houston, Texas) |
| ABSTRACT | Provided herein are methods for the treatment of brain metastasis by administering a kinase inhibitor targeted to a metastasis-promoting kinase identified by an in vivo kinase screen. |
| FILED | Friday, August 10, 2018 |
| APPL NO | 16/638222 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0085 (20130101) A61K 31/42 (20130101) A61K 31/52 (20130101) A61K 31/55 (20130101) Original (OR) Class A61K 31/427 (20130101) A61K 31/454 (20130101) A61K 31/4025 (20130101) A61K 31/4439 (20130101) A61K 31/4745 (20130101) A61K 31/5377 (20130101) A61K 31/7105 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406647 | Tonks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | COLD SPRING HARBOR LABORATORY (Cold Spring Harbor, New York); DEPYMED, INC. (Farmingdale, New York) |
| ASSIGNEE(S) | COLD SPRING HARBOR LABORATORY (Cold Spring Harbor, New York); DEPYMED, INC. (Farmingdale, New York) |
| INVENTOR(S) | Nicholas Tonks (Cold Spring Harbor, New York); Navasona Krishnan (Hawthorn Woods, Illinois); Andreas Grill (Farmingdale, New York); Howard Sard (Woburn, Massachusetts) |
| ABSTRACT | Provided is a method of forming a copper-containing complex, including contacting a sample containing copper with a compound of Formula I: wherein R is —OH or —O—CH3. Also provided is a method of inhibiting enzymatic activity of a kinase in a sample, including contacting the sample with a compound of Formula I. Further provided is a method of administering to a subject a pharmaceutical composition including a compound of Formula I optionally complexed with copper. Also provided is a pharmaceutical composition including copper complexed with a compound of Formula I. |
| FILED | Tuesday, November 06, 2018 |
| APPL NO | 16/761631 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/58 (20130101) Original (OR) Class A61K 31/4184 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406657 | Machielse et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MANDOS LLC (West Hollywood, California) |
| ASSIGNEE(S) | MANDOS LLC (West Hollywood, California) |
| INVENTOR(S) | Bernardus Nicolaas Machielse (North Potomac, Maryland); Allan Darling (North Potomac, Maryland) |
| ABSTRACT | This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C. |
| FILED | Tuesday, September 29, 2020 |
| APPL NO | 17/036148 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/0019 (20130101) A61K 9/0085 (20130101) A61K 31/724 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406677 | Gromeier et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Matthias Gromeier (Durham, North Carolina); John H. Sampson (Durham, North Carolina); Darell D. Bigner (Mebane, North Carolina); Annick Desjardins (Durham, North Carolina); Henry S. Friedman (Durham, North Carolina) |
| ABSTRACT | Human clinical use of a chimeric poliovirus construct has demonstrated excellent anti-tumor effect. The mechanism of action is believed to involve both viral oncolysis as well as immune recruitment, both of which lead to necrosis in the area of the tumor. No adverse effects have been observed. |
| FILED | Thursday, September 10, 2020 |
| APPL NO | 17/016699 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0085 (20130101) A61K 35/768 (20130101) Original (OR) Class A61K 41/00 (20130101) A61K 45/06 (20130101) A61K 51/081 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/32611 (20130101) C12N 2770/32632 (20130101) C12N 2770/32671 (20130101) C12N 2770/32733 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406687 | Wells et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Alan H. Wells (Pittsburgh, Pennsylvania); Cecelia C. Yates-Binder (Pittsburgh, Pennsylvania); Joel S. Schuman (New York, New York) |
| ABSTRACT | The present disclosure describes methods of treating angiogenic disorders of the eye, such as macular degeneration, restenosis following glaucoma treatment or diabetic retinopathy, by administering an activator of C-X-C chemokine receptor 3 (CXCR3). In some embodiments, the activator of CXCR3 is interferon-γ-inducible 10 kDa protein (IP-10) or a fragment or variant thereof, such as a fragment comprising or consisting of the C-terminal α-helix of IP-10. In other embodiments, the activator of CXCR3 is platelet factor 4 (PF4) or a fragment or variant thereof. |
| FILED | Friday, September 18, 2020 |
| APPL NO | 17/025572 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 38/195 (20130101) Original (OR) Class A61K 38/217 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406707 | Betts |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida) |
| ASSIGNEE(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida) |
| INVENTOR(S) | Brian Betts (Tampa, Florida) |
| ABSTRACT | Compositions and methods to reduce the risk of graft versus host disease (GVHD) in a subject receiving hematopoietic stem cell transplantation (HSCT). Also disclosed are methods for identifying patients receiving HSCT who are at risk for developing GVHD, methods for prognosing the severity of GVHD in a subject receiving HSCT, and methods for monitoring efficacy of a therapeutic for treatment of GVHD in a subject HSCT. |
| FILED | Tuesday, February 10, 2015 |
| APPL NO | 15/117913 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/255 (20130101) A61K 31/255 (20130101) A61K 31/381 (20130101) A61K 31/381 (20130101) A61K 31/436 (20130101) A61K 31/506 (20130101) A61K 31/506 (20130101) A61K 38/2013 (20130101) A61K 39/3955 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2039/505 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/248 (20130101) C07K 2317/24 (20130101) C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 33/56972 (20130101) G01N 2333/4706 (20130101) G01N 2440/14 (20130101) G01N 2800/50 (20130101) G01N 2800/52 (20130101) G01N 2800/245 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406709 | Rahimi |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Nader Rahimi (Westwood, Massachusetts) |
| ABSTRACT | Described herein are novel compositions comprising, for example, PDCL3 polypeptides having VEGFR-2 inhibitory activity, inhibitory PDCL3 antibodies and PDCL3-binding fragments thereof, or PDCL3 inhibitory nucleic acid molecules, and methods of their use in anti-angiogenesis and anti-tumor proliferation and invasiveness therapies, such as the treatment of cancer, as well as the treatment of those vascular diseases where pathological angiogenesis plays a role, such as in carotid artery disease, macular degeneration, and plaque neovascularization. Also described herein are novel compositions comprising engineered PDCL3 polypeptides having enhanced chaperone activity, recombinant cells comprising such engineered PDCL3 polypeptides having enhanced chaperone activity, and methods thereof for therapeutic protein production and in vitro protein synthesis. |
| FILED | Tuesday, September 15, 2015 |
| APPL NO | 15/510965 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/12 (20130101) A61K 31/12 (20130101) A61K 31/13 (20130101) A61K 31/13 (20130101) A61K 31/122 (20130101) A61K 31/122 (20130101) A61K 31/277 (20130101) A61K 31/277 (20130101) A61K 31/404 (20130101) A61K 31/404 (20130101) A61K 31/428 (20130101) A61K 31/428 (20130101) A61K 31/475 (20130101) A61K 31/475 (20130101) A61K 31/513 (20130101) A61K 31/513 (20130101) A61K 31/519 (20130101) A61K 31/519 (20130101) A61K 31/4035 (20130101) A61K 31/4035 (20130101) A61K 31/4709 (20130101) A61K 31/4709 (20130101) A61K 31/4748 (20130101) A61K 31/4748 (20130101) A61K 31/7115 (20130101) A61K 38/02 (20130101) A61K 38/1709 (20130101) A61K 39/39558 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/00 (20130101) C07K 14/47 (20130101) C07K 16/28 (20130101) C07K 17/00 (20130101) C07K 2319/00 (20130101) C07K 2319/30 (20130101) C07K 2319/31 (20130101) C07K 2319/35 (20130101) C07K 2319/40 (20130101) C07K 2319/90 (20130101) C07K 2319/705 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406714 | Luo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Foundation for the State University of New York (Syracuse, New York) |
| ASSIGNEE(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| INVENTOR(S) | Juntao Luo (Jamesville, New York); Wenzhe Huang (Fayetteville, New York); Yu Shao (Syracuse, New York); Changying Shi (Jamesville, New York) |
| ABSTRACT | Provided are functional segregated telodendrimers having, for example, two or three functional segments. The telodendrimers can have one or more crosslinking groups (e.g., reversible photocrosslinking groups). The telodendrimers can aggregate to form nanocarriers. Cargo such as drugs, imaging probes, and other materials may be sequestered in the core of the aggregates via non-covalent or covalent interactions with the telodendrimers. Such nanocarriers may be used in drug delivery applications and imaging applications. |
| FILED | Wednesday, August 21, 2013 |
| APPL NO | 13/972539 |
| ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5146 (20130101) A61K 47/34 (20130101) Original (OR) Class A61K 47/551 (20170801) A61K 47/554 (20170801) A61K 49/0054 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406719 | Achilefu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Samuel Achilefu (St. Louis, Missouri); Zongren Zhang (St. Louis, Missouri); Mikhail Berezin (St. Louis, Missouri) |
| ABSTRACT | The present invention provides dichromic fluorescent compounds, as well as processes for making and methods for using the dichromic fluorescent compounds. |
| FILED | Monday, April 04, 2016 |
| APPL NO | 15/090055 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0059 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/0032 (20130101) Original (OR) Class A61K 49/0056 (20130101) Peptides C07K 7/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406720 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Thomas D. Wang (Ann Arbor, Michigan); Juan Zhou (Ann Arbor, Michigan) |
| ABSTRACT | The present disclosure relates to Fibroblast Growth Factor Receptor 2-specific peptide reagents, methods for detecting epithelial-derived cancer cells such as esophageal, colorectal, gastric, pancreatic or breast carcinoma cells using the peptide reagents, and methods for targeting such cells using the peptide reagents. |
| FILED | Wednesday, June 20, 2018 |
| APPL NO | 16/625054 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0032 (20130101) Original (OR) Class A61K 49/0041 (20130101) A61K 49/0056 (20130101) Peptides C07K 1/13 (20130101) C07K 7/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406721 | Tsien et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Roger Y. Tsien (Eugene, Oregon); Eric T. Ahrens (Encinitas, California); Alexander A. Kislukhin (Englewood, Colorado) |
| ABSTRACT | This disclosure provides compositions of metal-binding fluorinated compounds and associated methods for producing cellular labels for tracking cells by magnetic resonance imaging (MRI), computed tomography (CT), positron emission tomography (PET), and related methods. |
| FILED | Wednesday, February 22, 2017 |
| APPL NO | 15/999690 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/10 (20130101) Original (OR) Class A61K 49/1806 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406722 | Lux et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Regents of The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Caroline de Gracia Lux (Austin, Texas); Jacques Lux (Austin, Texas); Alexander M. Vezeridis (Austin, Texas); Robert F. Mattrey (Austin, Texas) |
| ABSTRACT | Stable perfluorocarbon nanodroplet compositions with properties such as low-boiling points and small particle diameters are provided for improved performance in ultrasound imaging and therapeutic applications. Methods of producing stabilized nanodroplet compositions and methods of using the compositions are further provided to allow for improved performance in ultrasound imaging techniques and/or therapeutic applications. |
| FILED | Friday, March 16, 2018 |
| APPL NO | 15/923845 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/225 (20130101) Original (OR) Class A61K 49/226 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406736 | Badylak et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth Systems of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Stephen F. Badylak (West Lafayette, Indiana); George R. Fercana, Jr. (Pittsburgh, Pennsylvania); Thomas G. Gleason (Pittsburgh, Pennsylvania); Julie Anne Phillippi (Pittsburgh, Pennsylvania) |
| ABSTRACT | Provided herein are methods of making an ECM gel from vascular tissue. Also provided herein are ECM compositions prepared from vascular tissue, and methods of use of those compositions, for example in treatment of aneurysms, and for vascularization or re-vascularization. |
| FILED | Friday, January 13, 2017 |
| APPL NO | 16/070044 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/52 (20130101) A61L 27/225 (20130101) A61L 27/507 (20130101) A61L 27/3625 (20130101) Original (OR) Class A61L 27/3633 (20130101) A61L 27/3687 (20130101) A61L 27/3691 (20130101) A61L 2430/20 (20130101) Peptides C07K 14/75 (20130101) C07K 14/745 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2533/90 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406826 | Noble et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| INVENTOR(S) | Jack H. Noble (Nashville, Tennessee); Robert F. Labadie (Nashville, Tennessee); Benoit M. Dawant (Nashville, Tennessee) |
| ABSTRACT | A method for using information of patient-specific cochlea size and/or shape to determine a patient-customized cochlear implant electrode insertion and placement plan includes segmenting shapes of structures of interest (SOIs) of the cochlea in a pre-operative CT image of the cochlea using a shape model; defining a 3D modiolar hugging curve within the shape model of the SOIs as a sequence of points; automatically transforming the defined 3D modiolar hugging curve to the pre-operative CT image so as to obtain a modiolar curve in the cochlea; rigidly registering an EA shape model of the EA to the modiolar curve in the cochlea, thereby placing a resting state shape of the EA within the patient's SOIs such that the EA matches the modiolar curve in the cochlea; and determining a patient-customized insertion plan for electrode placement using the registered EA shape model. |
| FILED | Tuesday, April 24, 2018 |
| APPL NO | 16/607484 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/1076 (20130101) A61B 6/032 (20130101) A61B 34/10 (20160201) A61B 2034/105 (20160201) A61B 2034/107 (20160201) A61B 2034/108 (20160201) A61B 2505/05 (20130101) A61B 2562/043 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0541 (20130101) A61N 1/36039 (20170801) Original (OR) Class Image Data Processing or Generation, in General G06T 7/12 (20170101) G06T 7/181 (20170101) G06T 11/005 (20130101) G06T 2207/30008 (20130101) G06T 2211/424 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406845 | Robinson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Clifford G. Robinson (Chesterfield, Missouri); Phillip S. Cuculich (St. Louis, Missouri) |
| ABSTRACT | Disclosed are systems and methods for the treatment of cardiac arrhythmias. |
| FILED | Monday, November 07, 2016 |
| APPL NO | 15/773415 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/282 (20210101) A61B 5/318 (20210101) A61B 6/032 (20130101) A61B 6/503 (20130101) A61B 6/5247 (20130101) A61B 8/483 (20130101) A61B 8/488 (20130101) A61B 8/0883 (20130101) A61B 8/5261 (20130101) A61B 18/00 (20130101) A61B 2576/023 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/39 (20130101) A61N 5/00 (20130101) A61N 5/10 (20130101) A61N 5/1039 (20130101) Original (OR) Class A61N 5/1068 (20130101) A61N 5/1083 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406978 | Delemico et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Haemonetics Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Haemonetics Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Peter Delemico (Chicago, Illinois); Carlos G. Lopez-Espina (Evanston, Illinois); Gabriel Raviv (Glenview, Illinois) |
| ABSTRACT | A sample testing cartridge is usable to perform a variety of tests on a viscoelastic sample, such hemostasis testing on a whole blood or blood component sample. The cartridge includes a sample processing portion that is in fluid communication with a sample retention structure. A suspension, such as a beam, arm, cantilever or similar structure supports or suspends the sample retention portion relative to the sample processing portion in a unitary structure. In this manner, the sample retention portion may be placed into dynamic excitation responsive to excitation of the cartridge and correspondingly dynamic, resonant excitation of the sample contained within the sample retention portion, while the sample processing portion remains fixed. Observation of the excited sample yields data indicative of hemostasis. The data may correspond to hemostasis parameters such as time to initial clot formation, rate of clot formation, maximum clot strength and degree of clot lysis. |
| FILED | Friday, June 07, 2019 |
| APPL NO | 16/434194 |
| ART UNIT | 1796 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502 (20130101) B01L 3/50273 (20130101) Original (OR) Class B01L 3/502753 (20130101) B01L 2300/165 (20130101) B01L 2300/0663 (20130101) B01L 2300/0816 (20130101) B01L 2300/0877 (20130101) B01L 2400/0433 (20130101) B01L 2400/0481 (20130101) B01L 2400/0487 (20130101) B01L 2400/0638 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 11/16 (20130101) G01N 29/032 (20130101) G01N 29/036 (20130101) G01N 29/2418 (20130101) G01N 33/4905 (20130101) G01N 2291/0251 (20130101) G01N 2291/0427 (20130101) G01N 2291/02466 (20130101) G01N 2291/02818 (20130101) G01N 2291/02827 (20130101) G01N 2800/224 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407105 | Gregg, IV et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Robert D. Gregg, IV (Richardson, Texas); Edgar A. Bolivar (Richardson, Texas); David P. Allen (Richardson, Texas); Walter E. Voit (Dallas, Texas) |
| ABSTRACT | A dielectric elastomer system (DES) variable stiffness actuator (VSA) is provided. In an embodiment, the DES VSA includes a variable stiffness module (VSM). The VSM includes a DES that softens when energized and stiffens when unpowered, an outer frame, and an inner frame member. The stiffness of the DES is variable. The outer frame supports the DES and the inner frame member, which is disposed within the DES. The inner frame member is configured to be displaceable with respect to the outer frame. The DES VSA also includes an actuation motor mechanically coupled to the inner frame member that is configured to cause a force to be applied to the inner frame member and the actuation motor is configured to control an equilibrium position of the DES VSA. |
| FILED | Tuesday, December 15, 2020 |
| APPL NO | 17/122936 |
| ART UNIT | 2846 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/0009 (20130101) B25J 9/123 (20130101) B25J 9/1633 (20130101) Original (OR) Class B25J 9/1694 (20130101) B25J 19/068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407725 | Bearrood et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Thomas Edward Bearrood (Urbana, Illinois); Chelsea Diane Anorma (Urbana, Illinois); Jefferson Chan (Savoy, Illinois) |
| ABSTRACT | High aldehyde dehydrogenase 1A1 (ALDH1A1) activity has emerged as a reliable marker for the identification of both normal and cancer stem cells. Herein, is presented AlDeSense, a turn-on green fluorescent probe for aldehyde dehydrogenase 1A1 (ALDH1A1) and Ctrl-AlDeSense, a matching non-responsive reagent. AlDeSense exhibits a 20-fold fluorescent enhancement when treated with ALDH1A1. Through the application of surface marker antibody staining, tumorsphere assays, and assessment of tumorigenicity, the disclosed results show that cells exhibiting high AlDeSense signal intensity have properties of cancer stem cells. Herein, is also reported the development of a red congener, red-AlDeSense. Importantly, red-AlDeSense represents one of only a few examples of a turn-on sensor in the red region using the d-PeT quenching mechanism. |
| FILED | Wednesday, December 18, 2019 |
| APPL NO | 16/719012 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Heterocyclic Compounds C07D 311/82 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/0816 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/76 (20130101) G01N 33/573 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407726 | Ahmed et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Tonia S. Ahmed (Pasadena, California); T. Patrick Montgomery (Pasadena, California); Robert H. Grubbs (Pasadena, California) |
| ABSTRACT | This invention relates generally to the synthesis of E-macrocycles using stereoretentive ruthenium olefin metathesis catalysts supported by dithioiate ligands. Macrocycles were generated with excellent selectivity (>99% E) and in moderate to high/good yields (47% to 80% yield; 58% to 80% yield) from diene starting materials bearing two E-olefins or bearing one E-olefin and one terminal olefin, A variety of rings were constructed, ranging from 12- to 18-membered macrocycles, including the antibiotic recifeiolide. The invention has utility in the fields of organometallics and organic synthesis. |
| FILED | Tuesday, December 04, 2018 |
| APPL NO | 16/770153 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/226 (20130101) B01J 31/2208 (20130101) B01J 31/2273 (20130101) B01J 2231/546 (20130101) B01J 2531/821 (20130101) Heterocyclic Compounds C07D 313/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407727 | Piazza et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ADT Pharmaceuticals, LLC (Orange Beach, Alabama) |
| ASSIGNEE(S) | ADT PHARMACEUTICALS, LLC (Orange Beach, Alabama) |
| INVENTOR(S) | Gary A. Piazza (Daphne, Alabama); Xi Chen (Hoover, Alabama); Adam B. Keeton (Gardendale, Alabama); Michael R. Boyd (Orange Beach, Alabama) |
| ABSTRACT | Disclosed are compounds, for example, compounds of formula I, wherein R, R0, R1-R8, n, X, Y, Y′, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer. |
| FILED | Monday, March 30, 2020 |
| APPL NO | 16/834267 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/36 (20130101) A61K 31/36 (20130101) A61K 31/40 (20130101) A61K 31/40 (20130101) A61K 31/44 (20130101) A61K 31/44 (20130101) A61K 31/341 (20130101) A61K 31/341 (20130101) A61K 31/401 (20130101) A61K 31/445 (20130101) A61K 31/445 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Acyclic or Carbocyclic Compounds C07C 233/58 (20130101) C07C 235/32 (20130101) C07C 237/20 (20130101) C07C 2601/02 (20170501) C07C 2602/08 (20170501) Heterocyclic Compounds C07D 207/14 (20130101) C07D 207/337 (20130101) C07D 211/56 (20130101) C07D 213/24 (20130101) C07D 213/75 (20130101) C07D 235/30 (20130101) C07D 307/38 (20130101) C07D 307/52 (20130101) C07D 307/54 (20130101) C07D 317/64 (20130101) Original (OR) Class C07D 405/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407740 | Teng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Forge Therapeutics, Inc. (San Diego, California) |
| ASSIGNEE(S) | FORGE THERAPEUTICS, INC. (San Diego, California) |
| INVENTOR(S) | Min Teng (San Diego, California); Baskar Nammalwar (San Diego, California); Xiaoming Li (San Diego, California); Christian Perez (San Diego, California); Ian Yule (Abingdon, United Kingdom); Adele Faulkner (Abingdon, United Kingdom); Holly Atton (Abingdon, United Kingdom); Alastair Parkes (Abingdon, United Kingdom); Serge Convers-Reignier (Abingdon, United Kingdom); Michelle Southey (Abingdon, United Kingdom); David T. Puerta (San Diego, California) |
| ABSTRACT | Provided herein are heterocyclic derivative compounds of Formula (II), and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. Furthermore, the subject compounds and compositions are useful for the treatment of bacterial infection, such as urinary tract infection and the like. |
| FILED | Thursday, March 18, 2021 |
| APPL NO | 17/205750 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Heterocyclic Compounds C07D 239/54 (20130101) C07D 401/06 (20130101) C07D 401/10 (20130101) C07D 401/12 (20130101) C07D 403/10 (20130101) C07D 403/14 (20130101) Original (OR) Class C07D 405/12 (20130101) C07D 405/14 (20130101) C07D 409/12 (20130101) C07D 413/14 (20130101) C07D 487/04 (20130101) C07D 491/048 (20130101) C07D 491/107 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407747 | Werner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Inhibikase Therapeutics, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | Inhibikase Therapeutics, Inc. (Atlanta, Georgia) |
| INVENTOR(S) | Milton H. Werner (Marietta, Georgia); Terence A. Kelly (Ridgefield, Connecticut) |
| ABSTRACT | The present invention provides compounds for the prevention or treatment of cancer or a bacterial or viral infection. Additionally, the present invention provides compositions and methods for using these compounds and compositions in the prevention or treatment of cancer or a bacterial or viral infection in a subject. |
| FILED | Tuesday, January 05, 2021 |
| APPL NO | 17/141825 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) A61K 31/506 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 401/14 (20130101) C07D 403/14 (20130101) C07D 413/14 (20130101) C07D 417/14 (20130101) Original (OR) Class Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407771 | Holtzman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Washington University (Saint Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Michael J. Holtzman (St. Louis, Missouri); Arthur G. Romero (Chesterfield, Missouri); Benjamin J. Gerovac (St. Louis, Missouri); Zhenfu Han (St. Louis, Missouri); Shamus P. Keeler (University City, Missouri); Kangyun Wu (St. Louis, Missouri) |
| ABSTRACT | Compounds that inhibit mitogen-activated protein kinases (MAPKs) are disclosed. Some inhibitor compounds specifically target a single MAPK such as MAPK13, while others target multiple MAPKs such as MAPK13 and MAPK12. The compounds can be used therapeutically for a variety of diseases, including cancer and respiratory diseases. Methods of synthesis of the compounds are also disclosed. |
| FILED | Thursday, May 30, 2019 |
| APPL NO | 17/059251 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 213/75 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/0812 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407786 | Lu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Zheng-Rong Lu (Beachwood, Ohio); Amita M. Vaidya (Cleveland Heights, Ohio) |
| ABSTRACT | A nanosized complex includes siRNA and a compound comprising formula (I): |
| FILED | Monday, September 30, 2019 |
| APPL NO | 16/588362 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 5/0606 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 2310/14 (20130101) C12N 2310/3513 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407788 | Cheng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE CURATORS OF THE UNIVERSITY OF MISSOURI (Columbia, Missouri) |
| ASSIGNEE(S) | THE CURATORS OF THE UNIVERSITY OF MISSOURI (Columbia, Missouri) |
| INVENTOR(S) | Kun Cheng (Kansas City, Missouri); Wei Jin (Kansas City, Missouri) |
| ABSTRACT | Described herein is the discovery of novel PSMA-specific peptides, which were identified through a novel combinatorial biopanning method. One of the novel PSMA-specific peptides discovered, GTIQPYPFSWGY (or GTI) (SEQ ID NO: 2), exhibits high binding affinity and selectivity to PSMA and PSMA-positive prostate cancer cells. It was found that GTI can mediate internalization of the apoptotic KLA peptide to PSMA-positive LNCaP cells and induce cell death. Moreover, a FAM-labeled GTI peptide shows a high and specific tumor uptake in nude mice bearing human prostate cancer xenografts. It was demonstrated that the GTI peptide can be employed as a PSMA-specific ligand for prostate cancer diagnosis and/or for targeted drug delivery to prostate cancer cells. |
| FILED | Thursday, August 08, 2019 |
| APPL NO | 16/535720 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/10 (20130101) A61K 49/00 (20130101) A61K 49/0043 (20130101) A61K 49/0052 (20130101) Peptides C07K 7/08 (20130101) Original (OR) Class C07K 2319/33 (20130101) C07K 2319/035 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57434 (20130101) G01N 33/57492 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407802 | Payne et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Aimee S. Payne (Merion Station, Pennsylvania); Christoph T. Ellebrecht (Philadelphia, Pennsylvania); Vijay Bhoj (Philadelphia, Pennsylvania); Michael C. Milone (Cherry Hill, New Jersey) |
| ABSTRACT | The invention includes compositions comprising at least one chimeric autoantibody receptor (CAAR) specific for an autoantibody, vectors comprising the same, compositions comprising CAAR vectors packaged in viral particles, and recombinant T cells comprising the CAAR. The invention also includes methods of making a genetically modified T cell expressing a CAAR (CAART) wherein the expressed CAAR comprises a desmoglein extracellular domain. |
| FILED | Friday, April 19, 2019 |
| APPL NO | 16/389423 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0008 (20130101) A61K 48/00 (20130101) A61K 2039/57 (20130101) A61K 2039/5158 (20130101) Peptides C07K 14/705 (20130101) Original (OR) Class C07K 16/28 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407803 | Payne et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Aimee S. Payne (Merion Station, Pennsylvania); Christoph T. Ellebrecht (Philadelphia, Pennsylvania); Vijay Bhoj (Philadelphia, Pennsylvania); Michael C. Milone (Cherry Hill, New Jersey) |
| ABSTRACT | The invention includes compositions comprising at least one chimeric autoantibody receptor (CAAR) specific for an autoantibody, vectors comprising the same, compositions comprising CAAR vectors packaged in viral particles, and recombinant T cells comprising the CAAR. The invention also includes methods of making a genetically modified T cell expressing a CAAR (CAART) wherein the expressed CAAR comprises a desmoglein extracellular domain. |
| FILED | Monday, April 22, 2019 |
| APPL NO | 16/390638 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0008 (20130101) A61K 48/00 (20130101) A61K 2039/57 (20130101) A61K 2039/5158 (20130101) Peptides C07K 14/705 (20130101) Original (OR) Class C07K 16/28 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407804 | Payne et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Aimee S. Payne (Merion Station, Pennsylvania); Christoph T. Ellebrecht (Philadelphia, Pennsylvania); Vijay Bhoj (Philadelphia, Pennsylvania); Michael C. Milone (Cherry Hill, New Jersey) |
| ABSTRACT | The invention includes compositions comprising at least one chimeric autoantibody receptor (CAAR) specific for an autoantibody, vectors comprising the same, compositions comprising CAAR vectors packaged in viral particles, and recombinant T cells comprising the CAAR. The invention also includes methods of making a genetically modified T cell expressing a CAAR (CAART) wherein the expressed CAAR comprises a desmoglein extracellular domain. |
| FILED | Monday, April 22, 2019 |
| APPL NO | 16/390685 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0008 (20130101) A61K 48/00 (20130101) A61K 2039/57 (20130101) A61K 2039/5158 (20130101) Peptides C07K 14/705 (20130101) Original (OR) Class C07K 16/28 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407816 | Bornholdt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MAPP BIOPHARMACEUTICAL, INC. (San Diego, California); Albert Einstein College of Medicine (Bronx, New York); Adimab, LLC (Lebanon, New Hampshire) |
| ASSIGNEE(S) | MAPP BIOPHARMACEUTICAL, INC. (San Diego, California); ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York); ADIMAB, LLC (Lebanon, New Hampshire) |
| INVENTOR(S) | Zachary A. Bornholdt (Encinitas, California); Larry Zeitlin (San Diego, California); Kartik Chandran (Brooklyn, New York); Anna Wec (Lebanon, New Hampshire); Laura Walker (Norwich, Vermont) |
| ABSTRACT | Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially, similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus. |
| FILED | Tuesday, June 09, 2020 |
| APPL NO | 16/897013 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 2039/55 (20130101) A61K 2039/57 (20130101) A61K 2039/62 (20130101) A61K 2039/505 (20130101) A61K 2039/545 (20130101) A61K 2039/6075 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407817 | Bornholdt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MAPP BIOPHARMACEUTICAL, INC. (San Diego, California); Albert Einstein College of Medicine (Bronx, New York); Adimab, LLC (Lebanon, New Hampshire) |
| ASSIGNEE(S) | MAPP BIOPHARMACEUTICAL, INC. (San Diego, California); ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York); ADIMAB, LLC (Lebanon, New Hampshire) |
| INVENTOR(S) | Zachary A. Bornholdt (Encinitas, California); Larry Zeitlin (San Diego, California); Kartik Chandran (Brooklyn, New York); Anna Z. Wec (Lebanon, New Hampshire); Laura Walker (Norwich, Vermont) |
| ABSTRACT | Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus. |
| FILED | Tuesday, June 09, 2020 |
| APPL NO | 16/897027 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 2039/55 (20130101) A61K 2039/57 (20130101) A61K 2039/62 (20130101) A61K 2039/505 (20130101) A61K 2039/545 (20130101) A61K 2039/6075 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407818 | Hunsperger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Rockville, Maryland) |
| ASSIGNEE(S) | The United States of America, as Represented By The Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Elizabeth Anne Hunsperger (Guaynabo, Puerto Rico); Tesfaye Gelanew Taye (San Juan, Puerto Rico) |
| ABSTRACT | The present disclosure relates to polypeptides that specifically bind to Dengue virus non¬structural protein 1, including antibodies and fragments thereof. The antibody or antigen-binding fragment thereof may specifically bind Dengue virus (DENV) serotype 4 and include: a heavy chain variable region that comprises at least one CDR amino acid sequence selected from the group consisting of: SGYNWH, YIH YS GGTN YNPS LKS, RTGTVPFAY, SYVMH, YLNPYNDDTKYNEKFKG, and GPPYALDY. The present disclosure further relates to methods of producing the polypeptides of the present disclosure, methods of diagnosing DENV, and methods of treating a DENV infection. |
| FILED | Thursday, June 22, 2017 |
| APPL NO | 16/310964 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/167 (20130101) Peptides C07K 16/1081 (20130101) Original (OR) Class C07K 2317/14 (20130101) C07K 2317/24 (20130101) C07K 2317/565 (20130101) C07K 2319/02 (20130101) C07K 2319/30 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/62 (20130101) C12N 15/79 (20130101) C12N 2710/14041 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/185 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407820 | Thurman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of The University of Colorado (Denver, Colorado) |
| INVENTOR(S) | Joshua M. Thurman (Greenwood Village, Colorado); V. Michael Holers (Denver, Colorado) |
| ABSTRACT | Provided herein are compositions, including pharmaceutical compositions, and methods for modulating, i.e., stimulating or inhibiting, activity of the alternative complement pathway, and methods of identifying factor H-binding proteins. |
| FILED | Thursday, June 21, 2018 |
| APPL NO | 16/015071 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/177 (20130101) A61K 38/1709 (20130101) Peptides C07K 14/4721 (20130101) C07K 16/18 (20130101) Original (OR) Class C07K 2317/54 (20130101) C07K 2317/55 (20130101) C07K 2319/70 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) Enzymes C12Y 402/01002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407823 | Weiner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Howard L. Weiner (Brookline, Massachusetts); Galina Gabriely (Brookline, Massachusetts); Andre Pires Da Cunha (Boston, Massachusetts); Takatoku Oida (Osaka, Japan) |
| ABSTRACT | Described herein are compositions and methods relating to LAP-binding agents, including, for example, anti-LAP antibodies, and to their use in methods of treatment of cancer. LAP-binding agents affected both systemic and intra-tumor immunity and were shown effective to treat a broad spectrum of cancer types. |
| FILED | Friday, March 15, 2019 |
| APPL NO | 16/355544 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/3955 (20130101) A61K 39/39558 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/22 (20130101) Original (OR) Class C07K 16/30 (20130101) C07K 16/2839 (20130101) C07K 2317/24 (20130101) C07K 2317/54 (20130101) C07K 2317/55 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) C07K 2317/569 (20130101) C07K 2317/622 (20130101) C07K 2317/626 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57492 (20130101) G01N 2333/495 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
11407851 — Chemically modified shape memory polymer embolic foams with increased X-ray visualization
| US 11407851 | Nash et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | Landon D. Nash (Sunnyvale, California); Kendal P. Ezell (Tomball, Texas) |
| ABSTRACT | An embodiment includes a system comprising: an iodine containing thermoset open-cell shape memory polymer (SMP) foam that is x-ray visible; wherein (a) the SMP foam is configured to expand from a compressed secondary state to an expanded primary state in response to thermal stimulus, (b) the SMP foam is a poly(urethane-urea-amide). Other embodiments are described herein. |
| FILED | Friday, December 01, 2017 |
| APPL NO | 16/465555 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/73 (20130101) C08G 18/3206 (20130101) C08G 18/3215 (20130101) C08G 18/3275 (20130101) Original (OR) Class C08G 18/3821 (20130101) C08G 18/3897 (20130101) C08G 18/5018 (20130101) C08G 2110/005 (20210101) C08G 2280/00 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/08 (20130101) C08K 5/52 (20130101) C08K 5/0066 (20130101) C08K 7/02 (20130101) C08K 2003/0887 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407977 | Guire et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Innovative Surface Technologies, Inc. (St. Paul, Minnesota) |
| ASSIGNEE(S) | INNOVATIVE SURFACE TECHNOLOGIES, INC. (St. Paul, Minnesota) |
| INVENTOR(S) | Eric Guire (St. Paul, Minnesota); Christopher Bahr (Coon Rapids, Minnesota) |
| ABSTRACT | Inventive concepts relate generally to nanofibrous scaffolds useful for electrophysiological assays. Scaffolds include polymeric nanofibrous components and electrically excitable cells immobilized at a distinct cell seeding domains on the scaffold. Methods and kits including the scaffolds are also described. |
| FILED | Thursday, November 14, 2019 |
| APPL NO | 16/684560 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 25/14 (20130101) C12M 41/46 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) Original (OR) Class C12N 11/089 (20200101) C12N 11/096 (20200101) C12N 2533/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407985 | Cong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Le Cong (Cambridge, Massachusetts); David Benjamin Turitz Cox (Cambridge, Massachusetts); Matthias Heidenreich (Boston, Massachusetts); Randall Jeffrey Platt (Cambridge, Massachusetts); Lukasz Swiech (Boston, Massachusetts); Feng Zhang (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides for delivery, engineering and optimization of systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are delivery systems and tissues or organ which are targeted as sites for delivery. Also provided are vectors and vector systems some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors. Also provided are methods of directing CRISPR complex formation in eukaryotic cells to ensure enhanced specificity for target recognition and avoidance of toxicity and to edit or modify a target site in a genomic locus of interest to alter or improve the status of a disease or a condition. |
| FILED | Friday, June 10, 2016 |
| APPL NO | 15/179799 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 38/465 (20130101) A61K 48/00 (20130101) A61K 48/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 15/102 (20130101) C12N 15/907 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407990 | Zheng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Yuxuan Zheng (Davis, California); Claire Lorenzo (Davis, California); Peter Beal (Davis, California); Andrew Fisher (Davis, California); Leanna Monteleone (Davis, California) |
| ABSTRACT | In some aspects, the present invention provides methods and compositions for modifying target sites within nucleic acid molecules. In some embodiments, the methods comprise using adenosine deaminases that act on RNA (ADARs), and variants thereof, to modify target sites within DNA-RNA hybrid molecules. In other aspects, ADAR2 variant polypeptides as well as fusion proteins comprising an ADAR catalytic domain and a hybrid nucleic acid binding domain are provided, as are methods for use thereof. Methods for preventing and treating genetic disorders are also provided herein. |
| FILED | Monday, May 18, 2020 |
| APPL NO | 16/877020 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) C12N 9/78 (20130101) Original (OR) Class C12N 15/62 (20130101) Enzymes C12Y 305/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407998 | Glackin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | City of Hope (Duarte, California); The Regents of The University of California (Oakland, California) |
| ASSIGNEE(S) | City of Hope (Duarte, California); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Carlotta A. Glackin (Duarte, California); John J. Rossi (Azusa, California); Jeffrey I. Zink (Los Angeles, California); Fuyuhiko Tamanoi (Los Angeles, California); Cai M. Roberts (Duarte, California); James Finlay (Duarte, California) |
| ABSTRACT | The present invention relates to compositions comprising TWIST signaling inhibitors and optionally one or more anti-cancer agents, and methods of using the compositions for the treatment of cancer. |
| FILED | Friday, November 22, 2019 |
| APPL NO | 16/693145 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6923 (20170801) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/321 (20130101) C12N 2310/322 (20130101) C12N 2310/332 (20130101) C12N 2310/335 (20130101) C12N 2310/351 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11408030 | Madrid et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Andy Madrid (Madison, Wisconsin); Reid Spencer Alisch (Prairie du Sac, Wisconsin); Kirk Jeffrey Hogan (Madison, Wisconsin) |
| ASSIGNEE(S) | Andy Madrid (Madison, Wisconsin); Reid Spencer Alisch (Prairie du Sac, Wisconsin); Kirk Jeffrey Hogan (Madison, Wisconsin) |
| INVENTOR(S) | Andy Madrid (Madison, Wisconsin); Reid Spencer Alisch (Prairie du Sac, Wisconsin); Kirk Jeffrey Hogan (Madison, Wisconsin) |
| ABSTRACT | Provided herein is technology for Alzheimer's disease testing and particularly, but not exclusively, methods, compositions, and related uses for detecting the presence of Alzheimer's disease. |
| FILED | Monday, September 09, 2019 |
| APPL NO | 16/564948 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class C12Q 2600/154 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11408884 | Chiu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
| INVENTOR(S) | Daniel T. Chiu (Seattle, Washington); Wei Sun (Seattle, Washington); Jiangbo Yu (Seattle, Washington); Changfeng Wu (Changchun, China PRC); Fangmao Ye (Seattle, Washington) |
| ABSTRACT | Lyophilized chromophoric polymer dot compositions are provided. Also disclosed are methods of making and using the lyophilized compositions, methods of dispersing the lyophilized compositions in aqueous solutions and kits supplying the compositions. |
| FILED | Tuesday, December 03, 2019 |
| APPL NO | 16/702228 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/02 (20130101) C08G 73/00 (20130101) C08G 75/32 (20130101) C08G 2261/11 (20130101) C08G 2261/18 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/025 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/533 (20130101) G01N 33/582 (20130101) G01N 33/587 (20130101) G01N 33/588 (20130101) G01N 33/54393 (20130101) Original (OR) Class G01N 2650/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11408885 | Ahrens et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Caroline Chopko Ahrens (Kennett Square, Pennsylvania); Linda G. Griffith (Cambridge, Massachusetts); Steven Robert Tannenbaum (Brookline, Massachusetts); Christi Dionne Cook (Cambridge, Massachusetts); Ravindra Kodihalli (Acton, Massachusetts); Douglas A. Lauffenburger (Cambridge, Massachusetts); Evan L. Chiswick (Jamaica Plain, Massachusetts); Miles Miller (Cambridge, Massachusetts) |
| ABSTRACT | Proteases regulate a wide range of normal cellular functions where dysregulated activity is observed in various diseases. Compositions and methods use protease activity multiplexed bead-based immunoassays to profile protease activity. This platform technology integrates protease activity measurements with total protein quantification techniques. It represents a significant improvement over existing detection techniques by allowing for multiplexed, sensitive active protease measurements in complex biological samples. Exemplary multiplexed detections are realized in a single assay using a minute sample amount (e.g., 5 μl) for active recombinant MMP-1, -2, -3, -7, 9, and 12 and those same MMPs in cell culture supernatant, menstrual fluid effluent, and peritoneal aspirates. This multiplexed platform achieves high level of sensitivities equal to or better than existing leading single-plex detection strategies. It also allows for high throughput screening to identify inhibitors of proteases in complex, donor-derived samples. |
| FILED | Tuesday, August 28, 2018 |
| APPL NO | 16/115289 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/37 (20130101) Enzymes C12Y 304/24007 (20130101) C12Y 304/24024 (20130101) C12Y 304/24035 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/58 (20130101) G01N 33/533 (20130101) G01N 33/535 (20130101) G01N 33/573 (20130101) Original (OR) Class G01N 33/574 (20130101) G01N 33/54306 (20130101) G01N 33/54313 (20130101) G01N 33/54326 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 99/00 (20190201) Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 99/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11408890 | Boyden et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Edward Stuart Boyden (Chestnut Hill, Massachusetts); Jae-Byum Chang (Cambridge, Massachusetts); Fei Chen (Cambridge, Massachusetts); Paul Warren Tillberg (Cambridge, Massachusetts) |
| ABSTRACT | The present invention leverages the techniques for expansion microscopy (ExM) to provide improved high-throughput super-resolution whole-organ imaging methodology to image protein architectures over whole organs with nanoscale resolution by using high-throughput microscopes in combination with samples that have been iteratively expanded more than once, in a method referred to herein as “iterative expansion microscopy” (iExM). In the ExM method, biological samples of interest are permeated with a swellable material that results in the sample becoming embedded in the swellable material, and then the sample can be expanded isotropically in three dimensions The process of iteratively expanding the samples can be applied to samples that have been already expanded using ExM techniques one or more additional times to iteratively expand them such that, for example, a 5-fold expanded specimen can be expanded again 3- to 4-fold, resulting in as much as a 17- to 19-fold or more linear expansion. |
| FILED | Thursday, April 14, 2016 |
| APPL NO | 15/098799 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/36 (20130101) G01N 1/4044 (20130101) G01N 33/582 (20130101) Original (OR) Class G01N 2001/302 (20130101) G01N 2001/307 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11408892 | Min et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Wei Min (Edgewater, New Jersey); Lu Wei (Anhui, China PRC); Zhixing Chen (Beijing, China PRC); Fanghao Hu (New York, New York); Yihui Shen (Jiangsu, China PRC) |
| ABSTRACT | Methods, systems and computer-accessible medium for imaging a living cell or a living organism with bond-edited compounds using stimulated Raman scattering are disclosed. The method comprises the steps of introducing one or more bond-edited compounds into a live cell or a living organism, and detecting a vibrational tag in the cell or organism with stimulated Raman scattering. Also disclosed are methods for detecting a disease condition in a subject, methods for monitoring treatment for a disease condition, methods for screening an agent, methods for tracing a cellular process in a live cell using bond-edited compounds in combination with stimulated Raman scattering. Also disclosed are a composition for labeling a target cell with at least one bond-edited compound and devices for imaging bond-edited compounds by stimulated Raman scattering. |
| FILED | Friday, December 18, 2015 |
| APPL NO | 14/974992 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0013 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/583 (20130101) Original (OR) Class G01N 33/5005 (20130101) G01N 2021/655 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11408894 | Min et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Wei Min (Edgewater, New Jersey); Lu Wei (Anhui, China PRC); Zhixing Chen (Beijing, China PRC); Fanghao Hu (New York, New York); Yihui Shen (Jiangsu, China PRC) |
| ABSTRACT | Methods, systems and computer-accessible medium for imaging a living cell or a living organism with bond-edited compounds using stimulated Raman scattering are disclosed. The method comprises the steps of introducing one or more bond-edited compounds into a live cell or a living organism, and detecting a vibrational tag in the cell or organism with stimulated Raman scattering. Also disclosed are methods for detecting a disease condition in a subject, methods for monitoring treatment for a disease condition, methods for screening an agent, methods for tracing a cellular process in a live cell using bond-edited compounds in combination with stimulated Raman scattering. Also disclosed are a composition for labeling a target cell with at least one bond-edited compound and devices for imaging bond-edited compounds by stimulated Raman scattering. |
| FILED | Tuesday, December 17, 2019 |
| APPL NO | 16/717634 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0013 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/583 (20130101) Original (OR) Class G01N 33/5005 (20130101) G01N 2021/655 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11408897 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Lingjun Li (Madison, Wisconsin); Dustin Frost (Madison, Wisconsin); Amanda Buchberger Jones (Madison, Wisconsin) |
| ABSTRACT | The use of mass defect signatures to impart milliDalton mass differences between isotopically labeled peptides at the MS1-level allows multiplex quantification without the increased mass spectral complexity that occurs with mass difference approaches. Provided herein is a mass defect-based chemical tag, dimethyl pyrimidinyl ornithine (DiPyrO), that is compact and easy to synthesize at high purity in few steps using commercially available starting materials. The multiplex DiPyrO tags are amine-reactive and can impart a mass difference onto labeled peptides and through calculated substitution of heavy isotopes. DiPyrO offers up to 10-plex quantification on current Orbitrap or FT-ICR platforms without increasing mass spectral complexity. The synthesis of the DiPyrO tag is provided along with viability of the DiPyrO tag for labeling complex proteomics samples using yeast extract digests and its effect on labeled peptides during LC-MS2 analysis. Labeling and quantification of glycans and metabolites using the DiPyrO tag is also demonstrated. |
| FILED | Friday, October 14, 2016 |
| APPL NO | 15/768299 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 239/42 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6812 (20130101) G01N 33/6848 (20130101) Original (OR) Class G01N 2458/15 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11408899 | High et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Katherine A. High (Merion Station, Pennsylvania); Federico Mingozzi (Paris, France); Yifeng Chen (Philadelphia, Pennsylvania) |
| ABSTRACT | Virus vectors, virus particles, and methods and uses of screening for, detecting, analyzing and determining amounts of virus antibody, or neutralizing antibody activity of samples are provided. Such virus vectors, virus particles, and methods and uses are applicable to a broad range of virus types, such as lentiviruses, adenovirus, and adeno-associated virus (AAV) serotypes. Methods and uses include virus antibody screening, such as anti-virus immunoglobulins screened for, detected, analyzed and amounts determined. |
| FILED | Friday, July 11, 2014 |
| APPL NO | 14/904205 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 2750/14131 (20130101) C12N 2750/14143 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/701 (20130101) C12Q 1/6897 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6854 (20130101) Original (OR) Class G01N 2333/075 (20130101) G01N 2333/90241 (20130101) G01N 2469/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11408903 | Chiu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Daniel T. Chiu (Seattle, Washington); Bryant S. Fujimoto (Seattle, Washington); Jason E. Kreutz (Seattle, Washington) |
| ABSTRACT | Systems, methods, and devices for discretizing and analyzing fluidic samples are provided. In one aspect, a microfluidic array for discretizing a fluidic sample comprises one or more flow channels and a plurality of fluidic compartments in fluidic communication with the one or more flow channels. In another aspect, a system for discretizing and analyzing fluidic samples comprises a rotor assembly shaped to receive a microfluidic device. |
| FILED | Monday, August 31, 2020 |
| APPL NO | 17/008561 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5025 (20130101) B01L 3/502746 (20130101) B01L 7/52 (20130101) B01L 9/523 (20130101) B01L 2200/027 (20130101) B01L 2200/0673 (20130101) B01L 2300/18 (20130101) B01L 2300/0809 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2300/1894 (20130101) B01L 2400/0409 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1463 (20130101) G01N 21/6456 (20130101) G01N 35/04 (20130101) G01N 35/025 (20130101) G01N 35/00069 (20130101) G01N 35/1016 (20130101) Original (OR) Class G01N 2015/1006 (20130101) G01N 2035/00158 (20130101) G01N 2035/00356 (20130101) G01N 2035/00366 (20130101) G01N 2035/0449 (20130101) G01N 2035/1034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11409814 | Clauset et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado (Denver, Colorado) |
| INVENTOR(S) | Aaron Clauset (Louisville, Colorado); Allison C. Morgan (Boulder, Colorado); Samuel F. Way (Boulder, Colorado) |
| ABSTRACT | Embodiments herein provide for a more efficient web crawler (102) that accesses a plurality of links from a web page (106). In certain embodiments, the web crawler (102) determines link scores for each of the plurality of links, with each link score corresponding to a probability that the associated link leads to a web page (106) of a target page type. The plurality of links and the associated link scores are added to a priority queue (114). The web crawler (102) accesses a second web page (106) using the highest-ranked link in the priority queue (114), obtains links from that web page (106), identifies a link score for each of those links, and adds those links to the priority queue (114) based on their link scores. This process can be repeated for several pages, as needed, using the highest-rank link in each instance, until the crawler (102) identifies a web page (106) of a target page type. |
| FILED | Thursday, November 29, 2018 |
| APPL NO | 16/768420 |
| ART UNIT | 2161 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/951 (20190101) Original (OR) Class G06F 40/205 (20200101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6267 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11410360 | Ruth et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| INVENTOR(S) | Kimberly C. Ruth (Seattle, Washington); Tadayoshi Kohno (Seattle, Washington); Franziska Roesner (Seattle, Washington) |
| ABSTRACT | In some embodiments, a method of providing visual cues for private virtual objects is provided. In response to determining that presentation of a protected characteristic of a virtual object is not permitted by an augmented reality system, the augmented reality system presents a placeholder object. In some embodiments, a method of protecting a location from undesirable virtual objects is provided. In response to determining that a location for a virtual object is associated with a protected location, a low-invasiveness version of a mesh of the virtual object is presented. In some embodiments, a method of decoupling a virtual object from a static physical location is provided. |
| FILED | Friday, May 15, 2020 |
| APPL NO | 16/875833 |
| ART UNIT | 2616 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 21/604 (20130101) G06F 21/6218 (20130101) Image Data Processing or Generation, in General G06T 11/001 (20130101) G06T 11/60 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11410440 | Skala et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Melissa C. Skala (Middleton, Wisconsin); Anthony Gitter (Madison, Wisconsin); Zijie Wang (Madison, Wisconsin); Alexandra J. Walsh (Madison, Wisconsin) |
| ABSTRACT | Systems and methods for classifying and/or sorting T cells by activation state are disclosed. The system includes a cell classifying pathway, a single-cell autofluorescence image sensor, a processor, and a non-transitory computer-readable memory. The memory is accessible to the processor and has stored thereon a trained convolutional neural network and instructions. The instructions, when executed by the processor, cause the processor to: a) receive the autofluorescence intensity image; b) optionally pre-process the autofluorescence intensity image to produce an adjusted autofluorescence intensity image; c) input the autofluorescence intensity image or the adjusted autofluorescence intensity image into the trained convolutional neural network to produce an activation prediction for the T cell. |
| FILED | Thursday, August 13, 2020 |
| APPL NO | 16/992539 |
| ART UNIT | 2637 — Optical Communications |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6257 (20130101) G06K 9/6263 (20130101) G06K 9/6271 (20130101) Image or Video Recognition or Understanding G06V 10/454 (20220101) G06V 20/695 (20220101) G06V 20/698 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11410777 | Edelson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNIVERSITY OF CHICAGO (Chicago, Illinois) |
| ASSIGNEE(S) | THE UNIVERSITY OF CHICAGO (Chicago, Illinois) |
| INVENTOR(S) | Dana P. Edelson (Chicago, Illinois); Matthew Churpek (Chicago, Illinois); Robert Gibbons (Chicago, Illinois) |
| ABSTRACT | This disclosure includes various embodiments of apparatuses, systems and methods for evaluating a patient's cardiac risk and/or mental status. Cardiac risk evaluation may be based (e.g., only) on the patient's respiratory rate, heart rate, diastolic blood pressure, age, and/or mental status. An aggregate score, which is indicative likelihood of the patient's cardiac risk, may be calculated based (e.g., only) on the patient's respiratory rate, heart rate, diastolic blood pressure, age, and/or mental status. If the calculated aggregate score exceeds a predetermined threshold, the patient may be identified as having a critical cardiac risk, and actions may be taken to treat the patient. The cardiac risk evaluation may be based further on the patient's mental status, where the patient's mental status may be evaluated based on a game with visual indicators. |
| FILED | Friday, November 01, 2013 |
| APPL NO | 14/440251 |
| ART UNIT | 3687 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/021 (20130101) A61B 5/0205 (20130101) A61B 5/7275 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/30 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11410829 | Jing et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Euclid Beamlabs, LLC (Solon, Ohio) |
| ASSIGNEE(S) | Euclid Beamlabs, LLC (Solon, Ohio) |
| INVENTOR(S) | Chunguang Jing (Naperville, Illinois); Scott Ross (Cary, Illinois); Roman Kostin (Oak Park, Illinois); Yimei Zhu (East Setauket, New York) |
| ABSTRACT | A TEM sample holder enables simultaneous cooling and RF irradiation of a sample. The sample is suspended in a hole that penetrates through a sample stage formed by a dielectric plate having a lower metallic ground layer and an upper metallic lead. The sample stage is supported by an evacuated hollow tube extending from a cryogenic chamber, such as a liquid nitrogen or helium Dewar. A coaxial conductor extends from an ambient connector through the cryogenic chamber and hollow tube to the sample stage, a center conductor and surrounding metallic shield thereof being in thermal and electrical communication with the metallic lead and metallic ground layer respectively of the sample stage, and the metallic shield being is in direct thermal communication with the cryogenic chamber. The coaxial conductor thereby enables simultaneous cooling and RF irradiation of the sample during TEM measurements. Embodiments include a temperature sensor and heater. |
| FILED | Thursday, March 17, 2022 |
| APPL NO | 17/697034 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/20 (20130101) Original (OR) Class H01J 37/26 (20130101) H01J 2237/026 (20130101) H01J 2237/2001 (20130101) H01J 2237/24585 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11406269 | Mulligan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Flashback Technologies, Inc. (Boulder, Colorado); The Regents of the University of Colorado (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Isobel Jane Mulligan (Niwot, Colorado); Gregory Zlatko Grudic (Niwot, Colorado); Steven L. Moulton (Littleton, Colorado) |
| ABSTRACT | Novel tools and techniques are provided for assessing, predicting and/or estimating a probability that a patient is bleeding, in some cases, noninvasively. In various embodiments, tools and techniques are provided for implementing rapid detection of bleeding of the patient or implementing assessment, prediction, or estimation of a probability of bleeding of the patient following injury, in some instances, in real-time before, during, and after fluid resuscitation. According to some embodiments, one or more sensors might monitor physiological data of the patient before, during, and after resuscitation following injury. A computer system might receive and analyze the physiological data, and might estimate a probability that the patient is bleeding, based at least in part on the analyzed physiological data. An indication of at least one of an assessment, prediction, or estimate of a probability that the patient is bleeding may then be displayed on a display device. |
| FILED | Monday, June 12, 2017 |
| APPL NO | 15/620701 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/002 (20130101) A61B 5/029 (20130101) A61B 5/031 (20130101) A61B 5/0075 (20130101) A61B 5/0205 (20130101) A61B 5/318 (20210101) A61B 5/369 (20210101) A61B 5/398 (20210101) A61B 5/742 (20130101) A61B 5/0809 (20130101) A61B 5/02028 (20130101) A61B 5/02042 (20130101) Original (OR) Class A61B 5/02152 (20130101) A61B 5/02241 (20130101) A61B 5/02416 (20130101) A61B 5/4836 (20130101) A61B 5/4848 (20130101) A61B 5/4875 (20130101) A61B 5/6826 (20130101) A61B 5/7246 (20130101) A61B 5/7267 (20130101) A61B 5/7275 (20130101) A61B 5/14532 (20130101) A61B 5/14546 (20130101) A61B 5/14551 (20130101) A61B 7/04 (20130101) A61B 8/488 (20130101) A61B 2562/0219 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/1613 (20140204) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/17 (20180101) G16H 40/63 (20180101) G16H 50/20 (20180101) G16H 50/30 (20180101) G16H 50/50 (20180101) G16H 50/70 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406458 | Frederick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| INVENTOR(S) | Tom Frederick (Lincoln, Nebraska); Eric Markvicka (Brush, Colorado); Shane Farritor (Lincoln, Nebraska); Dmitry Oleynikov (Omaha, Nebraska) |
| ABSTRACT | The embodiments disclosed herein relate to various robotic and/or in vivo medical devices having compact joint configurations. Other embodiments relate to various medical device components, including forearms having grasper or cautery end effectors, that can be incorporated into certain robotic and/or in vivo medical devices. |
| FILED | Tuesday, August 13, 2019 |
| APPL NO | 16/538902 |
| ART UNIT | 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/14 (20130101) A61B 18/082 (20130101) A61B 18/1445 (20130101) A61B 34/30 (20160201) Original (OR) Class A61B 2017/00398 (20130101) A61B 2017/00407 (20130101) A61B 2017/00477 (20130101) A61B 2018/00595 (20130101) A61B 2018/1253 (20130101) A61B 2018/1422 (20130101) A61B 2034/305 (20160201) A61B 2217/005 (20130101) A61B 2217/007 (20130101) A61B 2218/002 (20130101) A61B 2218/007 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/046 (20130101) B25J 9/0087 (20130101) B25J 9/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406597 | Sailor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Michael J. Sailor (La Jolla, California); Byungji Kim (Cambridge, Massachusetts); Jinyoung Kang (La Jolla, California) |
| ABSTRACT | The disclosure describes a fusogenic liposome-coated porous silicon nanoparticles for high loading efficiency of anionic payloads (small molecules, dyes, nucleic acids), and for non-endocytic delivery of hydrophilic and lipophilic payloads by membrane fusion. The liposome coating can be further modified with targeting peptides or antibodies via covalent binding chemistry between the ligands and functionalized poly(ethylene glycol). The surface moieties can be transferred to the cellular membrane surface by fusogenic uptake. The composition of the disclosure can be applied in the treatment of diseases by delivering entrapped/encapsulated payloads. |
| FILED | Monday, July 06, 2020 |
| APPL NO | 16/920979 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 9/0051 (20130101) A61K 9/1271 (20130101) A61K 9/1272 (20130101) Original (OR) Class A61K 9/5115 (20130101) A61K 31/713 (20130101) A61K 47/64 (20170801) A61K 47/6923 (20170801) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 30/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406744 | Burbank et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NxStage Medical, Inc. (Lawrence, Massachusetts) |
| ASSIGNEE(S) | NxStage Medical, Inc. (Lawrence, Massachusetts) |
| INVENTOR(S) | Jeffrey H. Burbank (Manchester, Massachusetts); Dennis M. Treu (Castle Rock, Colorado); Daniel Joseph Rubery, Jr. (Windham, New Hampshire); Scott W. Newell (Ipswich, Massachusetts); James M. Brugger (Newburyport, Massachusetts); William J. Schnell (Libertyville, Illinois); William K. Weigel (Portland, Maine); Steven A. White (Hudson, Massachusetts); Mark T. Wyeth (Andover, Massachusetts); Jerome James (Vestavia, Alabama); David Desouza (Essex, Massachusetts); Joseph E. Turk, Jr. (North Andover, Massachusetts); Garrett Casey (Methuen, Massachusetts) |
| ABSTRACT | The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described. |
| FILED | Friday, November 13, 2020 |
| APPL NO | 17/097724 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/14 (20130101) A61M 1/34 (20130101) A61M 1/165 (20140204) A61M 1/341 (20140204) A61M 1/1605 (20140204) Original (OR) Class A61M 1/1613 (20140204) A61M 1/1615 (20140204) A61M 1/1647 (20140204) A61M 1/3403 (20140204) A61M 1/3434 (20140204) A61M 1/3437 (20140204) A61M 1/3441 (20130101) A61M 1/3444 (20140204) A61M 1/3448 (20140204) A61M 1/3607 (20140204) A61M 1/3609 (20140204) A61M 1/3635 (20140204) A61M 2205/15 (20130101) A61M 2205/058 (20130101) A61M 2205/502 (20130101) A61M 2205/702 (20130101) A61M 2205/3331 (20130101) A61M 2205/3334 (20130101) A61M 2205/3341 (20130101) A61M 2205/3351 (20130101) A61M 2205/3355 (20130101) A61M 2205/3365 (20130101) A61M 2205/3368 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406809 | Donaldson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Critical Innovations, LLC (Inglewood, California) |
| ASSIGNEE(S) | Critical Innovations, LLC (Inglewood, California) |
| INVENTOR(S) | Ross I. Donaldson (Inglewood, California); Oliver Buchanan (Inglewood, California); Tim Fisher (Inglewood, California); Jon Armstrong (Inglewood, California); John Cambridge (Inglewood, California) |
| ABSTRACT | An improved method and device are provided for forming and/or maintaining a percutaneous access pathway. The device generally comprises an access pathway and attachment device. The provided assembly substantially reduces the possibility of iatrogenic infection while accessing and/or re-accessing a body space. |
| FILED | Friday, September 25, 2020 |
| APPL NO | 16/948640 |
| ART UNIT | 3773 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/34 (20130101) A61B 17/3415 (20130101) A61B 17/3423 (20130101) A61B 17/3498 (20130101) A61B 90/40 (20160201) A61B 2017/345 (20130101) A61B 2017/00809 (20130101) A61B 2017/3492 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/02 (20130101) A61M 27/00 (20130101) A61M 39/0247 (20130101) Original (OR) Class A61M 2039/027 (20130101) A61M 2039/0252 (20130101) A61M 2039/0258 (20130101) A61M 2039/0261 (20130101) A61M 2039/0276 (20130101) A61M 2039/0279 (20130101) A61M 2039/0288 (20130101) A61M 2210/101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406956 | Tabor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Christopher E. Tabor (Kettering, Ohio); Carl J. Thrasher (Beavercreek, Ohio); Alexander M. Watson (Dayton, Ohio); Nicholas J. Morris (Dayton, Ohio); Zachary J. Farrell (Xenia, Ohio) |
| ABSTRACT | The present invention relates to articles comprising core shell liquid metal encapsulate networks and methods of using core shell liquid metal encapsulate networks to control AC signals and power. Such method permits the skilled artisan to control the radiation, transmission, reflection and modulation of an AC signal and power. As a result, AC system properties such as operation frequency, polarization, gain, directionality, insertion loss, return loss, and impedance can be controlled under strain. |
| FILED | Tuesday, September 24, 2019 |
| APPL NO | 16/580652 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/08 (20130101) Original (OR) Class Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/02 (20130101) H01B 1/08 (20130101) H01B 1/12 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 3/00 (20130101) Antennas, i.e Radio Aerials H01Q 1/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406975 | Goyal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Girija Goyal (Cambridge, Massachusetts); Donald E. Ingber (Boston, Massachusetts) |
| ABSTRACT | An organ-on-a-chip microfluidic device is disclosed that mimics a human lymph node and/or human lymphoid tissue. The device can include cells from human blood and lymphatic tissue, include an extracellular matrix for the development of immune system components, and provide for the perfusion of fluids and solids resembling blood and lymphatic fluid within micrometer sized channels. |
| FILED | Tuesday, July 18, 2017 |
| APPL NO | 16/318591 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 35/28 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/00 (20180101) A61P 35/00 (20180101) A61P 37/04 (20180101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) Original (OR) Class B01L 2300/0861 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/16 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0018 (20130101) C12N 5/069 (20130101) C12N 5/0635 (20130101) C12N 5/0636 (20130101) C12N 5/0645 (20130101) C12N 5/0651 (20130101) C12N 5/0693 (20130101) C12N 2531/00 (20130101) C12N 2533/52 (20130101) C12N 2533/54 (20130101) C12N 2533/90 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406997 | Fontana et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jake Fontana (Alexandria, Virginia); Jawad Naciri (Arlington, Virginia) |
| ABSTRACT | An apparatus having: a vessel for containing a suspension of a liquid and solid particles; a tube having a narrowed portion to draw the suspension from the vessel into the tube when a gas flows through the tube; an aerosol generator coupled to the tube for forming an aerosol from the suspension; a dehydrator coupled to the aerosol generator for removing the liquid from the aerosol forming a dried aerosol; a multiple-pass spectroscopic absorption cell coupled to the dehydrator to pass the dried aerosol into the absorption cell; and a Fourier transform spectrometer coupled to the absorption cell to measure an absorption spectrum of the dried aerosol. |
| FILED | Friday, February 07, 2020 |
| APPL NO | 16/784534 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Spraying Apparatus; Atomising Apparatus; Nozzles B05B 9/0403 (20130101) B05B 12/004 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/031 (20130101) G01N 21/3504 (20130101) G01N 2001/1025 (20130101) G01N 2021/3595 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407028 | Sherman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Powdermet, Inc. (Euclid, Ohio) |
| ASSIGNEE(S) | POWDERMET, INC. (Euclid, Ohio) |
| INVENTOR(S) | Andrew Sherman (Mentor, Ohio); Brian Doud (Euclid, Ohio) |
| ABSTRACT | A syntactic metal foam composite that is substantially fully dense except for syntactic porosity is formed from a mixture of ceramic microballoons and matrix forming metal. The ceramic microballoons have a uniaxial crush strength and a much higher omniaxial crush strength. The mixture is continuously constrained while it is consolidated. The constraining force is less than the omniaxial crush strength. The substantially fully dense syntactic metal foam composite is then constrained and deformation worked at a substantially constant volume. The deformation working is typically performed at a yield strength that is adjusted by way of selecting a working temperature at which the yield strength is approximately less than the omniaxial crush strength of the included ceramic microballoons. This deformation causes at least work hardening and grain refinement in the matrix metal. |
| FILED | Monday, July 09, 2018 |
| APPL NO | 16/030082 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working or Processing of Sheet Metal or Metal Tubes, Rods or Profiles Without Essentially Removing Material; Punching Metal B21D 31/00 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/02 (20130101) B22F 3/10 (20130101) B22F 3/16 (20130101) B22F 3/1112 (20130101) Original (OR) Class B22F 2003/185 (20130101) B22F 2003/185 (20130101) B22F 2003/1106 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/16 (20130101) B32B 5/18 (20130101) B32B 5/20 (20130101) Alloys C22C 1/1084 (20130101) C22C 1/1084 (20130101) C22C 1/1084 (20130101) C22C 32/0031 (20130101) C22C 32/0036 (20130101) C22C 32/0078 (20130101) C22C 49/00 (20130101) C22C 49/06 (20130101) C22C 49/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407185 | Ingram et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Timothy Scott Ingram (New Castle, Delaware); Timothy Emile Brochon (Conshohocken, Pennsylvania) |
| ABSTRACT | Systems and methods are provided for adjustable tooling. One embodiment is a method that includes laying up a laminate of fiber reinforced material onto a continuous surface that has a convex profile and that comprises a first contoured surface of a fixed mold of a composite layup tool and a second contoured surface of a movable mold of the composite layup tool. The method also includes displacing the movable mold in a direction that is at least partially towards the fixed mold, breaking the continuous surface and releasing the laminate from the composite layup tool. |
| FILED | Monday, December 18, 2017 |
| APPL NO | 15/845640 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 31/08 (20130101) B29C 33/68 (20130101) B29C 33/485 (20130101) B29C 37/0003 (20130101) B29C 70/30 (20130101) Original (OR) Class B29C 70/44 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/3076 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407483 | Bognar |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John A. Bognar (Belgrade, Montana) |
| ASSIGNEE(S) | Anasphere, Inc. (Belgrade, Montana) |
| INVENTOR(S) | John A. Bognar (Belgrade, Montana) |
| ABSTRACT | This invention relates to a thermal hydrogen generator and a process and system for generating hydrogen gas, more specifically to a process and system for generating hydrogen gas by thermally decomposing a metal hydride. |
| FILED | Monday, January 13, 2020 |
| APPL NO | 16/741508 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 7/00 (20130101) Lighter-than Air Aircraft B64B 1/58 (20130101) B64B 1/62 (20130101) Original (OR) Class Non-metallic Elements; Compounds Thereof; C01B 3/04 (20130101) Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 43/00 (20130101) C06B 45/00 (20130101) Meteorology G01W 1/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407657 | Yang, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey) |
| INVENTOR(S) | Eui-Hyeok Yang, Jr. (Fort Lee, New Jersey); Jian Xu (West Lafayette, Indiana); Wei Xu (Farmingdale, New York); Brendan Englot (New York, New York); Chang-Hwan Choi (Tenafly, New Jersey) |
| ABSTRACT | Smart membranes (14) are integrated into a small, unmanned surface vessel (20) to enable the efficient, automated cleanup of oil spills. Such a vessel (20) has the potential to provide a low-cost, modular solution for day-to-day oil-spill cleanup operations, especially in confined aquatic areas, such as under piers and in the small spaces between marine vessels and piers. The smart membranes (14) are provided on the surface of a conveyor belt (34) that circulates the membranes (14) through the surrounding body of water (10) for oil collection, as well as through an internal reduction chamber (22) of the vessel (20) for oil release. The smart membranes (14) are adapted to attract and repel oil (12) in response to low-voltage commands applied across the conveyor belt (34), using a process that is repeatable for a number of cycles, offering high efficiency and long durability (FIG. 5). |
| FILED | Tuesday, December 04, 2018 |
| APPL NO | 16/766066 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/40 (20130101) Original (OR) Class C02F 1/285 (20130101) C02F 2101/32 (20130101) C02F 2103/007 (20130101) C02F 2301/08 (20130101) C02F 2303/16 (20130101) C02F 2305/04 (20130101) C02F 2305/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407726 | Ahmed et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Tonia S. Ahmed (Pasadena, California); T. Patrick Montgomery (Pasadena, California); Robert H. Grubbs (Pasadena, California) |
| ABSTRACT | This invention relates generally to the synthesis of E-macrocycles using stereoretentive ruthenium olefin metathesis catalysts supported by dithioiate ligands. Macrocycles were generated with excellent selectivity (>99% E) and in moderate to high/good yields (47% to 80% yield; 58% to 80% yield) from diene starting materials bearing two E-olefins or bearing one E-olefin and one terminal olefin, A variety of rings were constructed, ranging from 12- to 18-membered macrocycles, including the antibiotic recifeiolide. The invention has utility in the fields of organometallics and organic synthesis. |
| FILED | Tuesday, December 04, 2018 |
| APPL NO | 16/770153 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/226 (20130101) B01J 31/2208 (20130101) B01J 31/2273 (20130101) B01J 2231/546 (20130101) B01J 2531/821 (20130101) Heterocyclic Compounds C07D 313/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407771 | Holtzman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Washington University (Saint Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Michael J. Holtzman (St. Louis, Missouri); Arthur G. Romero (Chesterfield, Missouri); Benjamin J. Gerovac (St. Louis, Missouri); Zhenfu Han (St. Louis, Missouri); Shamus P. Keeler (University City, Missouri); Kangyun Wu (St. Louis, Missouri) |
| ABSTRACT | Compounds that inhibit mitogen-activated protein kinases (MAPKs) are disclosed. Some inhibitor compounds specifically target a single MAPK such as MAPK13, while others target multiple MAPKs such as MAPK13 and MAPK12. The compounds can be used therapeutically for a variety of diseases, including cancer and respiratory diseases. Methods of synthesis of the compounds are also disclosed. |
| FILED | Thursday, May 30, 2019 |
| APPL NO | 17/059251 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 213/75 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/0812 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407792 | Silberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WILLIAM MARSH RICE UNIVERSITY (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Jonathan Silberg (Houston, Texas); Joshua T. Atkinson (Houston, Texas); Ian J. Campbell (Houston, Texas); George N. Bennett (Houston, Texas) |
| ABSTRACT | Engineered protein electron carriers, microorganisms expressing the same, and methods detecting regulated electron flow are described. |
| FILED | Friday, November 09, 2018 |
| APPL NO | 16/186226 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/21 (20130101) Original (OR) Class C07K 14/415 (20130101) C07K 2319/00 (20130101) C07K 2319/73 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/542 (20130101) G01N 33/566 (20130101) G01N 2333/79 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407816 | Bornholdt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MAPP BIOPHARMACEUTICAL, INC. (San Diego, California); Albert Einstein College of Medicine (Bronx, New York); Adimab, LLC (Lebanon, New Hampshire) |
| ASSIGNEE(S) | MAPP BIOPHARMACEUTICAL, INC. (San Diego, California); ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York); ADIMAB, LLC (Lebanon, New Hampshire) |
| INVENTOR(S) | Zachary A. Bornholdt (Encinitas, California); Larry Zeitlin (San Diego, California); Kartik Chandran (Brooklyn, New York); Anna Wec (Lebanon, New Hampshire); Laura Walker (Norwich, Vermont) |
| ABSTRACT | Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially, similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus. |
| FILED | Tuesday, June 09, 2020 |
| APPL NO | 16/897013 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 2039/55 (20130101) A61K 2039/57 (20130101) A61K 2039/62 (20130101) A61K 2039/505 (20130101) A61K 2039/545 (20130101) A61K 2039/6075 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407817 | Bornholdt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MAPP BIOPHARMACEUTICAL, INC. (San Diego, California); Albert Einstein College of Medicine (Bronx, New York); Adimab, LLC (Lebanon, New Hampshire) |
| ASSIGNEE(S) | MAPP BIOPHARMACEUTICAL, INC. (San Diego, California); ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York); ADIMAB, LLC (Lebanon, New Hampshire) |
| INVENTOR(S) | Zachary A. Bornholdt (Encinitas, California); Larry Zeitlin (San Diego, California); Kartik Chandran (Brooklyn, New York); Anna Z. Wec (Lebanon, New Hampshire); Laura Walker (Norwich, Vermont) |
| ABSTRACT | Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus. |
| FILED | Tuesday, June 09, 2020 |
| APPL NO | 16/897027 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 2039/55 (20130101) A61K 2039/57 (20130101) A61K 2039/62 (20130101) A61K 2039/505 (20130101) A61K 2039/545 (20130101) A61K 2039/6075 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11408007 | Isaacs et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | Farren J. Isaacs (Stamford, Connecticut); Ryan Gallagher (New Haven, Connecticut); Jaymin Patel (New Haven, Connecticut); Alexis Rovner (Cambridge, Massachusetts) |
| ABSTRACT | Methods and strategies for introducing genetic safeguards into microorganisms, genetically modified organisms (GMO) including the safeguards, and methods of use thereof are provided. The genetic safeguards generally impart a low escape frequency, are robust, and are modular. Safeguards with low escape frequency prevent the rise of mutants escaping defined media and limit growth in the wild. Robust safeguards retain wild-type levels of fitness while also maintaining containment in diverse growth conditions. |
| FILED | Monday, September 28, 2015 |
| APPL NO | 15/514749 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 1/36 (20130101) C12N 1/205 (20210501) C12N 15/70 (20130101) Original (OR) Class C12N 15/74 (20130101) C12N 15/79 (20130101) C12N 15/102 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 1/00 (20130101) C12P 1/04 (20130101) C12P 21/02 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/19 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11408039 | Shen-Gunther |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of The United States, as represented by The Secretary of The Army (Fort Detrick, Maryland) |
| ASSIGNEE(S) | The Government of The United States, as represented by The Secretary of The Army (Fort Detrick, Maryland) |
| INVENTOR(S) | Jane Shen-Gunther (San Antonio, Texas) |
| ABSTRACT | Disclosed herein are methods for molecularly characterizing cervical cell samples as being negative for intraepithelial lesion or malignancy (NILM), low-grade squamous intraepithelial lesion (LSIL), or high-grade squamous intraepithelial lesion (HSIL). |
| FILED | Wednesday, September 30, 2020 |
| APPL NO | 17/038290 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/708 (20130101) C12Q 1/6851 (20130101) C12Q 1/6883 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/154 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11408296 | Simonds et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Mark E. Simonds (Cape Neddick, Maine); Steven J. Feigleson (Falmouth, Maine) |
| ABSTRACT | A vane stage includes an arcuate platform defining an axial centerline axis having a pair of flanges that extend radially inward from the platform. The flanges are axially spaced from one another and from respective forward and aft ends of the platform. The vane stage includes a vane extending radially outward from the platform and a seal carrier mounted to the flanges of the platform. A method for constructing a vane stage includes sliding a seal carrier between flanges of an arcuate platform. Each flange includes at least a pair of through holes and interfaces with a respective axial side of the seal carrier. The method includes drilling through holes in each axial side of the seal carrier by using the through holes of each flange as guides. |
| FILED | Monday, February 11, 2019 |
| APPL NO | 16/272175 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/041 (20130101) Original (OR) Class F01D 11/001 (20130101) F01D 11/003 (20130101) F01D 25/005 (20130101) F01D 25/243 (20130101) F01D 25/246 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/10 (20130101) F05D 2230/60 (20130101) F05D 2240/12 (20130101) F05D 2240/55 (20130101) F05D 2240/80 (20130101) F05D 2300/133 (20130101) F05D 2300/603 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11408911 | Krueger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| INVENTOR(S) | Neil Krueger (Saint Paul, Minnesota); Matthew Puckett (Phoenix, Arizona); Chad Fertig (Bloomington, Minnesota); Arthur Savchenko (Kirkland, Washington); Steven Tin (Plymouth, Minnesota); Joshua Dorr (Minneapolis, Minnesota) |
| ABSTRACT | This disclosure is related to devices, systems, and techniques for inducing mechanical vibration in one or more mechanical structures. For example, a system includes a mechanical structure extending along a longitudinal axis. The mechanical structure includes a set of mechanical beams, where the set of mechanical beams are configured to guide a modulated optical signal, and where the set of mechanical beams includes a first mechanical beam and a second mechanical beam separated by a gap. The first mechanical beam includes at least one of a first corrugated inner edge parallel to the longitudinal axis and a first corrugated outer edge parallel to the longitudinal axis. The second mechanical beam includes at least one of a second corrugated inner edge parallel to the longitudinal axis and a second corrugated outer edge parallel to the longitudinal axis. |
| FILED | Wednesday, July 17, 2019 |
| APPL NO | 16/514905 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 9/00 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/093 (20130101) Original (OR) Class G01P 15/097 (20130101) G01P 15/0802 (20130101) G01P 2015/0814 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11408912 | Dorr et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| INVENTOR(S) | Joshua Dorr (Minneapolis, Minnesota); Chad Fertig (Bloomington, Minnesota); Arthur Savchenko (Kirkland, Washington); Steven Tin (Plymouth, Minnesota); Neil Krueger (Saint Paul, Minnesota) |
| ABSTRACT | An optomechanical device for producing and detecting optical signals comprising a proof mass assembly, one or more laser devices, and a circuit. The one or more laser devices are configured to generate a first optical signal and a second optical signal. The circuit is configured to modulate, with an electro-optic modulator (EOM), the second optical signal, output the first optical signal and the second optical signal to the proof mass assembly, generate a filtered optical signal corresponding to a response by the proof mass assembly to the first optical signal without the second optical signal, and generate an electrical signal based on the filtered optical signal, wherein the EOM modulates the second optical signal based on the electrical signal. |
| FILED | Tuesday, August 13, 2019 |
| APPL NO | 16/539974 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/093 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11408961 | Zalalutdinov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Maxim K. Zalalutdinov (Silver Spring, Maryland); Douglas M. Photiadis (Falls Church, Virginia); Joseph A. Bucaro (Herndon, Virginia); Brian H. Houston (Fairfax, Virginia) |
| ABSTRACT | Systems and methods are provided for sensing acoustic signals using a floating base vector sensor. A vector sensor according to an embodiment of the present disclosure can be used to detect and characterize low frequency sound wave(s) in a viscous medium (e.g., air, water, etc.) by detecting a periodic motion of the media particles associated with the sound wave(s). The orientation of the particle velocity deduced from such measurements can provide information regarding the wave vector of the sound wave(s), can define the direction of arrival (DOA) for the acoustic signal, and can assist locating the source of the sound of interest. |
| FILED | Thursday, February 20, 2020 |
| APPL NO | 16/796033 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/801 (20130101) G01S 3/8034 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11408986 | Huang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (, None) |
| INVENTOR(S) | Dehua Huang (Newport, Rhode Island); Gregory A Blasdell (Wakefield, Rhode Island); Gaivorlor D Borbor (Pawtucket, Rhode Island) |
| ABSTRACT | A method for calibrating an acoustic calibration tank providing the tanks with reference hydrophones positioned along the tank. The tank is filled with a fluid at a known temperature and pressure. A calibrated reverse hydrophone is positioned in the tank, opposite one of the reference hydrophones. A known acoustic wave is created in the tank using the calibrated reverse hydrophone and the opposite reference hydrophone output is measured. Free field voltage sensitivity is computed for the reference hydrophone. This gives the calibration factor for the reference hydrophone. The calibrated reverse hydrophone can be repositioned. An iterative process can be utilized for the other reference hydrophones, and other known pressures and temperatures. |
| FILED | Friday, September 13, 2019 |
| APPL NO | 16/570336 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/52004 (20130101) Original (OR) Class G01S 15/04 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 1/38 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 1/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11409044 | Su et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Analog Photonics LLC (Boston, Massachusetts) |
| ASSIGNEE(S) | Analog Photonics LLC (Boston, Massachusetts) |
| INVENTOR(S) | Zhan Su (Boston, Massachusetts); Erman Timurdogan (Somerville, Massachusetts); Michael Robert Watts (Hingham, Massachusetts) |
| ABSTRACT | A polarization rotator structure includes: a first core structure formed at a first layer, extending from the first end to a second end, and a second core structure formed at a second layer that is at a different depth than the first layer and formed in proximity to the first core structure. The first core structure and the second core structure provide mode hybridization between at least two orthogonally polarized waveguide modes of the PRS. An optical splitter structure is optically coupled at a first end to the second end of the PRS, and optically coupled at a second end to at least two optical waveguides, and includes: a first core structure that is contiguous with at least one of the first or second core structures of the PRS, and a second core structure that is separate from both of the first and second core structures of the PRS. |
| FILED | Friday, April 30, 2021 |
| APPL NO | 17/245385 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/14 (20130101) G02B 6/125 (20130101) G02B 6/126 (20130101) G02B 6/276 (20130101) G02B 6/1228 (20130101) G02B 6/2726 (20130101) G02B 6/2733 (20130101) G02B 6/2766 (20130101) Original (OR) Class G02B 6/2773 (20130101) G02B 6/12002 (20130101) G02B 6/12004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11409527 | Studer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Christoph Emanuel Studer (Ithaca, New York); Oscar Fernando Castañeda Fernandez (New York, New York) |
| ABSTRACT | A parallel processor in associative content-addressable memory (PPAC) is provided. Processing in memory (PIM) moves computation into memories with the goal of improving throughput and energy-efficiency compared to traditional von Neumann-based architectures. Most existing PIM architectures are either general-purpose but only support atomistic operations, or are specialized to accelerate a single task. The PPAC described herein provides a novel in-memory accelerator that supports a range of matrix-vector-product (MVP)-like operations that find use in traditional and emerging applications. PPAC is, for example, able to accelerate low-precision neural networks, exact/approximate hash lookups, cryptography, and forward error correction. The fully-digital nature of PPAC enables its implementation with standard-cell-based complementary metal-oxide-semiconductor (CMOS), which facilitates automated design and portability among technology nodes. A comparison with recent digital and mixed-signal PIM accelerators reveals that PPAC is competitive in terms of throughput and energy-efficiency, while accelerating a wide range of applications and simplifying development. |
| FILED | Wednesday, July 15, 2020 |
| APPL NO | 16/929463 |
| ART UNIT | 2181 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 7/57 (20130101) G06F 7/5443 (20130101) G06F 9/30029 (20130101) G06F 9/30036 (20130101) Original (OR) Class G06F 9/30087 (20130101) Static Stores G11C 11/4094 (20130101) G11C 15/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11409539 | Walker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | Dean E. Walker (Allen, Texas); Tony Brewer (Plano, Texas); Chris Baronne (Allen, Texas) |
| ABSTRACT | Devices and techniques for on-demand programmable atomic kernel loading are described herein. A programmable atomic unit (PAU) of a memory controller can receive an invocation of a programmable atomic operator by the memory controller. The PAU can then perform a verification on a programmable atomic operator partition for the programmable atomic operator. Here, the programmable atomic operator partition is located in a memory of the PAU. The PAU can then signal a trap in response to the verification indicating that the programmable atomic operator partition is not prepared. |
| FILED | Tuesday, October 20, 2020 |
| APPL NO | 17/075055 |
| ART UNIT | 2187 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 9/4403 (20130101) Original (OR) Class G06F 12/1458 (20130101) G06F 2212/1052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11409630 | Shao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Zhong Shao (Branford, Connecticut); Ronghui Gu (New Haven, Connecticut); Vilhelm Sjoberg (New Haven, Connecticut); Jieung Kim (New Haven, Connecticut); Jeremie Koenig (New Haven, Connecticut) |
| ABSTRACT | Systems and methods for formal verification of programs. The systems and methods provide a new game-theoretical, strategy-based compositional semantic model for concurrency, a set of formal linking theorems for composing multithreaded and multicore concurrent layers, and a compiler that supports certified thread-safe compilation and linking. Verification of an overlay interface can include determining an intermediate strategy for a primitive operation running on an underlay interface and refining that intermediate strategy to a strategy running on the overlay interface by applying a vertical and a horizontal composition rule. The refined strategy can then be composed with compatible strategies running on the overlay interface according to a parallel composition rule. Strategies may be compatible when rely conditions imposed by each strategy satisfy guarantees provided by the other strategies. The system and method of formal verification can be applied to formal verification of smart contracts. |
| FILED | Wednesday, November 28, 2018 |
| APPL NO | 16/767569 |
| ART UNIT | 2198 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 11/3608 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11409919 | Kane |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Michael G. Kane (Princeton, New Jersey) |
| ABSTRACT | A device includes a substrate, an array of metal pads on a first surface of the substrate, a carbon polymer composite covering the array of metal pads, the composite having variations that result in random resistance values between the metal pads usable as a random code. A method of manufacturing a secure device, including forming an array of metal pads on a dielet substrate, the dielet substrate containing at least one memory in which is stored an encryption key, and an RF communication section, covering the array of metal pads with a carbon polymer composite such that variations in the carbon concentration in the polymer forms a unique pattern of resistance, attaching the dielet substrate to a host component, receiving a request from a security server for a unique code determined by the unique pattern of resistance, and using the encryption key, encrypting and providing the unique code to the security server. |
| FILED | Thursday, April 16, 2020 |
| APPL NO | 16/850743 |
| ART UNIT | 2493 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/73 (20130101) G06F 21/86 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/073 (20130101) Ciphering or Deciphering Apparatus for Cryptographic or Other Purposes Involving the Need for Secrecy G09C 1/00 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0866 (20130101) H04L 63/0428 (20130101) H04L 2209/12 (20130101) H04L 2209/805 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11410017 | Modha |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Dharmendra S. Modha (San Jose, California) |
| ABSTRACT | Embodiments of the invention provide a neural network comprising multiple functional neural core circuits, and a dynamically reconfigurable switch interconnect between the functional neural core circuits. The interconnect comprises multiple connectivity neural core circuits. Each functional neural core circuit comprises a first and a second core module. Each core module comprises a plurality of electronic neurons, a plurality of incoming electronic axons, and multiple electronic synapses interconnecting the incoming axons to the neurons. Each neuron has a corresponding outgoing electronic axon. In one embodiment, zero or more sets of connectivity neural core circuits interconnect outgoing axons in a functional neural core circuit to incoming axons in the same functional neural core circuit. In another embodiment, zero or more sets of connectivity neural core circuits interconnect outgoing and incoming axons in a functional neural core circuit to incoming and outgoing axons in a different functional neural core circuit, respectively. |
| FILED | Friday, August 16, 2019 |
| APPL NO | 16/543319 |
| ART UNIT | 2182 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 13/4068 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) Original (OR) Class G06N 3/063 (20130101) Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 10/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11410270 | Bruder et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Gerd Bruder (Orlando, Florida); Gregory Welch (Orlando, Florida); Kangsoo Kim (Orlando, Florida); Zubin Choudhary (Orlando, Florida) |
| ABSTRACT | One or more cameras capture objects at a higher resolution than the human eye can perceive. Objects are segmented from the background of the image and scaled to human perceptible size. The scaled-up objects are superimposed over the unscaled background. This is presented to a user via an augmented reality display whereby the process selectively amplifies the size of the objects' spatially registered retinal projection while maintaining a natural (unmodified) view in the remainder of the visual field. |
| FILED | Wednesday, May 26, 2021 |
| APPL NO | 17/330679 |
| ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 3/40 (20130101) Original (OR) Class G06T 7/73 (20170101) G06T 7/194 (20170101) G06T 19/006 (20130101) Image or Video Recognition or Understanding G06V 10/764 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11410746 | Veneziano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Remi Veneziano (Allston, Massachusetts); Sakul Ratanalert (Cambridge, Massachusetts); Tyson Shepherd (Arlington, Massachusetts); Hyungmin Jun (Arlington, Massachusetts); Mark Bathe (Cambridge, Massachusetts) |
| ABSTRACT | Methods for the top-down design of nucleic acid nanostructures of arbitrary geometry based on target shape of spherical or non-spherical topology are described. The methods facilitate 3D molecular programming of lipids, proteins, sugars, and RNAs based on a DNA scaffold of arbitrary 2D or 3D shape. Geometric objects are rendered as node-edge networks of parallel nucleic acid duplexes, and a nucleic acid scaffold routed throughout the network using a spanning tree formula. Nucleic acid nanostructures produced according to top-down design methods are also described. In some embodiments, the nanostructures include single-stranded nucleic acid scaffold, DX crossovers, and staple strands. In other embodiments, the nanostructures include single-stranded nucleic acid scaffold, PX crossovers and no staples. Modified nanostructures include chemically modified nucleotides and conjugated to other molecules are described. |
| FILED | Thursday, April 27, 2017 |
| APPL NO | 16/097596 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/26 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/10 (20130101) C12N 15/11 (20130101) C12N 2320/32 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 15/00 (20190201) Original (OR) Class G16B 15/10 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11410931 | Coffey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida); The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | University of Central Florida Research Founation, Inc. (Orlando, Florida); The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Kevin R. Coffey (Oviedo, Florida); Edward Dein (Saint Cloud, Florida); Sameer Ezzat (Mosul, Iraq); Prabhu Doss Mani (Memphis, Tennessee); Katayun Barmak (Elmsford, New York) |
| ABSTRACT | Crystallographic orientations of ruthenium films and related methods are disclosed. Single crystal ruthenium films are provided with crystallographic orientations that arrange a c-axis of the ruthenium crystal structure in a direction that corresponds with a plane of the film or along a direction that corresponds with a surface of a substrate on which the film is formed. While ruthenium films typically form with the c-axis perpendicular to the surface of the substrate or as a polycrystalline film with a random crystallographic orientation, substrate surfaces may be configured with a crystallographic surface net that promotes non-perpendicular c-axis orientations of ruthenium. The substrate may be formed with a metal-terminated surface in certain arrangements. In this regard, ruthenium films may be configured as metallic interconnects for devices where directions of lowest electrical resistivity within the crystal structure are arranged to correspond with the direction of current flow in the devices. |
| FILED | Tuesday, June 09, 2020 |
| APPL NO | 16/896356 |
| ART UNIT | 2819 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/32051 (20130101) H01L 23/528 (20130101) H01L 23/53214 (20130101) H01L 23/53257 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11411129 | King et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | Richard R. King (Thousand Oaks, California); Christopher M. Fetzer (Valencia, California); Peter C. Colter (Canyon Country, California) |
| ABSTRACT | A solar cell includes a first layer having a first-layer lattice parameter, a second layer having a second-layer lattice parameter different from the first-layer lattice parameter, wherein the second layer includes a photoactive second-layer material; and a third layer having a third-layer lattice parameter different from the second-layer lattice parameter, wherein the third layer includes a photoactive third-layer material. A transparent buffer layer extends between and contacts the second layer and the third layer and has a buffer-layer lattice parameter that varies with increasing distance from the second layer toward the third layer, so as to lattice match to the second layer and to the third layer. There may be additional subcell layers and buffer layers in the solar cell. |
| FILED | Thursday, January 30, 2020 |
| APPL NO | 16/777638 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0687 (20130101) Original (OR) Class H01L 31/0735 (20130101) H01L 31/1852 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/544 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/50 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11411218 | Barsoum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Michel W Barsoum (Moorestown, New Jersey); Babak Anasori (Norristown, Pennsylvania); Yury Gogotsi (Warminster, Pennsylvania) |
| ABSTRACT | The present disclosure is directed to compositions comprising at least one layer having first and second surfaces, each layer comprising: a substantially two-dimensional array of crystal cells, each crystal cell having an empirical formula of M′2M″nXn+1, such that each X is positioned within an octahedral array of M′ and M″; wherein M′ and M″ each comprise different Group 11113, WE, VB, or VIB metals; each X is C, N, or a combination thereof; n=1 or 2; and wherein the M′ atoms are substantially present as two-dimensional outer arrays of atoms within the two-dimensional array of crystal cells; the M″ atoms are substantially present as two-dimensional inner arrays of atoms within the two-dimensional array of crystal cells; and the two dimensional inner arrays of M″ atoms are sandwiched between the two-dimensional outer arrays of M′ atoms within the two-dimensional army of crystal cells. |
| FILED | Friday, June 05, 2020 |
| APPL NO | 16/894056 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 21/0602 (20130101) C01B 32/90 (20170801) C01B 32/907 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/20 (20130101) C01P 2002/70 (20130101) C01P 2002/85 (20130101) C01P 2006/40 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/02 (20130101) C30B 29/36 (20130101) C30B 29/38 (20130101) C30B 29/60 (20130101) C30B 29/68 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/58 (20130101) Original (OR) Class H01M 10/0525 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11411258 | Taylor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Faraday Technology, Inc. (Englewood, Ohio) |
| ASSIGNEE(S) | Faraday Technology, Inc. (Englewood, Ohio) |
| INVENTOR(S) | Earl Jennings Taylor (Troy, Ohio); Maria E. Inman (Yellow Springs, Ohio); Timothy D. Hall (Englewood, Ohio); Danny Xin Liu (Tipp City, Ohio) |
| ABSTRACT | The problem of high rate electrodeposition of metals such as copper during electrowinning operations or high rate charging of lithium or zinc electrodes for rechargeable battery applications while avoiding the adverse effects of dendrite formation such as causing short-circuiting and/or poor deposit morphology is solved by pulse reverse current electrodeposition or charging whereby the forward cathodic (electrodeposition or charging) pulse current is “tuned” to minimize dendrite formation for example by creating a smaller pulsating boundary layer and thereby minimizing mass transport effects leading to surface asperities and the subsequent reverse anodic (electropolishing) pulse current is “tuned” to eliminate the micro- and macro-asperities leading to dendrites. |
| FILED | Wednesday, September 04, 2019 |
| APPL NO | 16/560172 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor C25C 7/06 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/0447 (20130101) H01M 10/44 (20130101) Original (OR) Class H01M 10/052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11411367 | Benedick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Andrew Benedick (Stow, Massachusetts); Kevin Creedon (Belmont, Massachusetts); John J. Zayhowski (Cambridge, Massachusetts) |
| ABSTRACT | Multi-stage fiber amplifiers can amplify signals from a few Watts to several kilowatts. These amplifiers are limited in power by intensity instabilities resulting from a sequence of nonlinear optical effects. These nonlinear optical effects include stimulated Brillouin scattering (SBS), with produces a high-intensity pulse close to the signal wavelength that propagates backward up the amplifier chain, causing permanent damage to the upstream components. This SBS pulse can be blocked by an optical isolator that blocks backward-propagating light at or near the signal wavelength. At high enough power levels, the SBS pulse can also induce backward-propagating light at wavelengths tens to hundreds of nanometers away from the signal wavelength. This SBS-Pulse Induced Non-linear Spectrum light is outside the isolator's reject band, so it can propagate upstream and de-stabilize the upstream amplifier stages. It can be suppressed using a filter with a broad reject band and a suppression ratio of ≥30 dB, enabling higher power operation. |
| FILED | Monday, March 23, 2020 |
| APPL NO | 16/826372 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0064 (20130101) H01S 3/302 (20130101) Original (OR) Class H01S 3/06779 (20130101) H01S 3/08027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11412075 | Patrick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | David Patrick (McKinney, Texas); Tony Brewer (Plano, Texas) |
| ABSTRACT | Implementations of the present disclosure are directed to systems and methods for processing headers that support multiple protocols. A header of a packet includes a bridge type (BTYPE) field that indicates the protocol of the packet. A command field of the packet is interpreted differently based on the value of the BTYPE field. Among the benefits of implementations of the present disclosure is that a single network may be used to carry packets of different protocols without the overhead of encapsulation. |
| FILED | Monday, August 31, 2020 |
| APPL NO | 17/007748 |
| ART UNIT | 2448 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 47/2441 (20130101) H04L 69/16 (20130101) H04L 69/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11412617 | Petelik et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Thomas Petelik (Alexandria, Virginia); Steven Bode (Alexandria, Virginia); Matthew Anderson (Hanover, Maryland) |
| ABSTRACT | An apparatus for interfacing with an RF/microwave subsystem is provided. The apparatus includes a printed circuit board that includes: a controller, and a connector constructed to provide control signals and power signals to a subsystem in accordance with instructions from the controller, and a mechanical interface constructed to provide a mechanical connection between the subsystem and the printed circuit board. |
| FILED | Thursday, April 23, 2020 |
| APPL NO | 16/857129 |
| ART UNIT | 2848 — Electrical Circuits and Systems |
| CURRENT CPC | Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 12/716 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/181 (20130101) Original (OR) Class H05K 2201/10189 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11406266 | Jornet et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Foundation for the State University of New York (Buffalo, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Amherst, New York) |
| INVENTOR(S) | Josep Jornet (Clarence Center, New York); Liang Feng (Amherst, New York); Edward P. Furlani (Lancaster, New York); Qiaoqiang Gan (East Amherst, New York); Zhi Sun (Clarence Center, New York); Yun Wu (East Amherst, New York) |
| ABSTRACT | A system is provided for advanced health monitoring and diagnosis based on wearable nano-biosensing networks. Nanophotonic and wireless communication technologies are synergistically leveraged to bridge the gap between nano-biosensing technologies and commercial wearable devices. Embodiments of the presently-disclosed system may include: (1) a nanoplasmonic biochip, implanted subcutaneously and built on a flexible substrate; (2) a nanophotonic smart band or wearable device that is able to collect in-vivo signals on-demand and relay them wirelessly to the user's smartphone by means of a secure data transfer; and (3) advanced signal processing techniques implemented on a remote processor to extract relevant data from the received signals and provide a diagnosis in real-time. |
| FILED | Wednesday, December 19, 2018 |
| APPL NO | 16/956465 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0004 (20130101) A61B 5/0017 (20130101) Original (OR) Class A61B 5/0022 (20130101) A61B 5/14735 (20130101) A61B 2562/146 (20130101) A61B 2562/0285 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406269 | Mulligan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Flashback Technologies, Inc. (Boulder, Colorado); The Regents of the University of Colorado (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Isobel Jane Mulligan (Niwot, Colorado); Gregory Zlatko Grudic (Niwot, Colorado); Steven L. Moulton (Littleton, Colorado) |
| ABSTRACT | Novel tools and techniques are provided for assessing, predicting and/or estimating a probability that a patient is bleeding, in some cases, noninvasively. In various embodiments, tools and techniques are provided for implementing rapid detection of bleeding of the patient or implementing assessment, prediction, or estimation of a probability of bleeding of the patient following injury, in some instances, in real-time before, during, and after fluid resuscitation. According to some embodiments, one or more sensors might monitor physiological data of the patient before, during, and after resuscitation following injury. A computer system might receive and analyze the physiological data, and might estimate a probability that the patient is bleeding, based at least in part on the analyzed physiological data. An indication of at least one of an assessment, prediction, or estimate of a probability that the patient is bleeding may then be displayed on a display device. |
| FILED | Monday, June 12, 2017 |
| APPL NO | 15/620701 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/002 (20130101) A61B 5/029 (20130101) A61B 5/031 (20130101) A61B 5/0075 (20130101) A61B 5/0205 (20130101) A61B 5/318 (20210101) A61B 5/369 (20210101) A61B 5/398 (20210101) A61B 5/742 (20130101) A61B 5/0809 (20130101) A61B 5/02028 (20130101) A61B 5/02042 (20130101) Original (OR) Class A61B 5/02152 (20130101) A61B 5/02241 (20130101) A61B 5/02416 (20130101) A61B 5/4836 (20130101) A61B 5/4848 (20130101) A61B 5/4875 (20130101) A61B 5/6826 (20130101) A61B 5/7246 (20130101) A61B 5/7267 (20130101) A61B 5/7275 (20130101) A61B 5/14532 (20130101) A61B 5/14546 (20130101) A61B 5/14551 (20130101) A61B 7/04 (20130101) A61B 8/488 (20130101) A61B 2562/0219 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/1613 (20140204) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/17 (20180101) G16H 40/63 (20180101) G16H 50/20 (20180101) G16H 50/30 (20180101) G16H 50/50 (20180101) G16H 50/70 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406458 | Frederick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| INVENTOR(S) | Tom Frederick (Lincoln, Nebraska); Eric Markvicka (Brush, Colorado); Shane Farritor (Lincoln, Nebraska); Dmitry Oleynikov (Omaha, Nebraska) |
| ABSTRACT | The embodiments disclosed herein relate to various robotic and/or in vivo medical devices having compact joint configurations. Other embodiments relate to various medical device components, including forearms having grasper or cautery end effectors, that can be incorporated into certain robotic and/or in vivo medical devices. |
| FILED | Tuesday, August 13, 2019 |
| APPL NO | 16/538902 |
| ART UNIT | 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/14 (20130101) A61B 18/082 (20130101) A61B 18/1445 (20130101) A61B 34/30 (20160201) Original (OR) Class A61B 2017/00398 (20130101) A61B 2017/00407 (20130101) A61B 2017/00477 (20130101) A61B 2018/00595 (20130101) A61B 2018/1253 (20130101) A61B 2018/1422 (20130101) A61B 2034/305 (20160201) A61B 2217/005 (20130101) A61B 2217/007 (20130101) A61B 2218/002 (20130101) A61B 2218/007 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/046 (20130101) B25J 9/0087 (20130101) B25J 9/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406595 | Subramanian et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Deepa Subramanian (Greenbelt, Maryland); Mikhail A. Anisimov (Beltsville, Maryland) |
| ABSTRACT | The present invention is related to a mesoscale colloidal particle including a hydrophobe-rich core surrounded by hydrogen bonded outer shell. The outer shell includes water and at least one hydrotrope wherein the hydrotrope molecules form hydrogen bonds with water molecules. The invention is also related to an aqueous solution including at least one mesoscale colloidal particle as well as methods of making and using such mesoscale colloidal particles and their solutions. |
| FILED | Tuesday, May 21, 2013 |
| APPL NO | 13/899126 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) Original (OR) Class A61K 47/6905 (20170801) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/0034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406597 | Sailor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Michael J. Sailor (La Jolla, California); Byungji Kim (Cambridge, Massachusetts); Jinyoung Kang (La Jolla, California) |
| ABSTRACT | The disclosure describes a fusogenic liposome-coated porous silicon nanoparticles for high loading efficiency of anionic payloads (small molecules, dyes, nucleic acids), and for non-endocytic delivery of hydrophilic and lipophilic payloads by membrane fusion. The liposome coating can be further modified with targeting peptides or antibodies via covalent binding chemistry between the ligands and functionalized poly(ethylene glycol). The surface moieties can be transferred to the cellular membrane surface by fusogenic uptake. The composition of the disclosure can be applied in the treatment of diseases by delivering entrapped/encapsulated payloads. |
| FILED | Monday, July 06, 2020 |
| APPL NO | 16/920979 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 9/0051 (20130101) A61K 9/1271 (20130101) A61K 9/1272 (20130101) Original (OR) Class A61K 9/5115 (20130101) A61K 31/713 (20130101) A61K 47/64 (20170801) A61K 47/6923 (20170801) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 30/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406792 | Ren et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dacheng Ren (Manlius, China PRC); Huan Gu (Syracuse, China PRC) |
| ASSIGNEE(S) | Syracuse University (Syracuse, New York) |
| INVENTOR(S) | Dacheng Ren (Manlius, China PRC); Huan Gu (Syracuse, China PRC) |
| ABSTRACT | A system of topographic patterns for the prevention of bacterial adhesion and biofilm formation. The patterns may be provided on the surfaces of certain devices that are prone to bacterial adhesion and biofilm formation, such as urinary catheters. To reduce bacterial adhesion and biofilm formation, and to remove existing biofilms, the patterns are induced to transform from a first topography to a second topography. For example, the surface patterns may be formed from a shape memory polymer and then heated to transform the patterns from the first topography to the second topography to dislodge bacteria and prevent fouling. |
| FILED | Tuesday, November 05, 2019 |
| APPL NO | 16/674199 |
| ART UNIT | 3781 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 29/14 (20130101) A61L 29/041 (20130101) A61L 29/041 (20130101) A61L 2400/16 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/0017 (20130101) Original (OR) Class A61M 2025/006 (20130101) A61M 2025/0056 (20130101) A61M 2025/0058 (20130101) Compositions of Macromolecular Compounds C08L 33/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407031 | Kotov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Nicholas A. Kotov (Ypsilanti, Michigan); Dawei Deng (Nanjing, China PRC); Wenfeng Jiang (Shanghai, China PRC); Douglas Montjoy (Ann Arbor, Michigan) |
| ABSTRACT | Self-assembly methods are provided for making hedgehog-shaped microparticles or nanoparticles. The method may comprise combining a metal-containing (e.g., Fe, Au) precursor, a chalcogen-containing precursor (e.g., Se, S), and a self-assembly additive (e.g., dodecanethiol (DT), oleylamine (OLA), hexadecyltrimethylammonium bromide (CTAB)). At least one hedgehog-shaped nanoscale, mesoscale, or microscale particle is formed that defines a core region formed of a first material and a plurality of needles connected to and substantially orthogonal to a surface of the core region. The needles comprise a second material. At least one of the first or the second material comprises iron or gold and optionally selenium or sulfur, for example, iron diselenide (FeSe2). Hedgehog-shaped microparticles or nanoparticles formed from such self-assembly methods are also provided. The semiconductor nature of FeSe2 hedgehog-shaped particles enables their utilization in biomimetic catalysis, drug delivery, optics, and energy storage, by way of non-limiting example. |
| FILED | Thursday, September 27, 2018 |
| APPL NO | 16/651841 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/07 (20220101) B22F 1/16 (20220101) B22F 1/054 (20220101) B22F 1/0553 (20220101) B22F 9/24 (20130101) Original (OR) Class Nanostructures Formed by Manipulation of Individual Atoms, Molecules, or Limited Collections of Atoms or Molecules as Discrete Units; Manufacture or Treatment Thereof B82B 1/00 (20130101) B82B 3/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407657 | Yang, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey) |
| INVENTOR(S) | Eui-Hyeok Yang, Jr. (Fort Lee, New Jersey); Jian Xu (West Lafayette, Indiana); Wei Xu (Farmingdale, New York); Brendan Englot (New York, New York); Chang-Hwan Choi (Tenafly, New Jersey) |
| ABSTRACT | Smart membranes (14) are integrated into a small, unmanned surface vessel (20) to enable the efficient, automated cleanup of oil spills. Such a vessel (20) has the potential to provide a low-cost, modular solution for day-to-day oil-spill cleanup operations, especially in confined aquatic areas, such as under piers and in the small spaces between marine vessels and piers. The smart membranes (14) are provided on the surface of a conveyor belt (34) that circulates the membranes (14) through the surrounding body of water (10) for oil collection, as well as through an internal reduction chamber (22) of the vessel (20) for oil release. The smart membranes (14) are adapted to attract and repel oil (12) in response to low-voltage commands applied across the conveyor belt (34), using a process that is repeatable for a number of cycles, offering high efficiency and long durability (FIG. 5). |
| FILED | Tuesday, December 04, 2018 |
| APPL NO | 16/766066 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/40 (20130101) Original (OR) Class C02F 1/285 (20130101) C02F 2101/32 (20130101) C02F 2103/007 (20130101) C02F 2301/08 (20130101) C02F 2303/16 (20130101) C02F 2305/04 (20130101) C02F 2305/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407726 | Ahmed et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Tonia S. Ahmed (Pasadena, California); T. Patrick Montgomery (Pasadena, California); Robert H. Grubbs (Pasadena, California) |
| ABSTRACT | This invention relates generally to the synthesis of E-macrocycles using stereoretentive ruthenium olefin metathesis catalysts supported by dithioiate ligands. Macrocycles were generated with excellent selectivity (>99% E) and in moderate to high/good yields (47% to 80% yield; 58% to 80% yield) from diene starting materials bearing two E-olefins or bearing one E-olefin and one terminal olefin, A variety of rings were constructed, ranging from 12- to 18-membered macrocycles, including the antibiotic recifeiolide. The invention has utility in the fields of organometallics and organic synthesis. |
| FILED | Tuesday, December 04, 2018 |
| APPL NO | 16/770153 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/226 (20130101) B01J 31/2208 (20130101) B01J 31/2273 (20130101) B01J 2231/546 (20130101) B01J 2531/821 (20130101) Heterocyclic Compounds C07D 313/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407770 | Ma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of South Florida (Tampa, Florida); Zhejiang University (Hangzhou, China PRC) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); ZHEJIANG UNIVERSITY (Hangzhou, China PRC) |
| INVENTOR(S) | Shengqian Ma (Tampa, Florida); Feng-Shou Xiao (Hangzhou, China PRC); Qi Sun (Tampa, Florida) |
| ABSTRACT | A variety of amphiphobic porous materials are provided. The materials can include a variety of porous frameworks that have an outer surface functionalized by a plurality of perfluoroalkyl moieties. By careful selection of appropriate perfluoralkyl moieties, hydrophobic properties can be imparted to the exterior surface of the porous materials without significantly impacting the wetting properties of the porous interior. This can be used to create a variety of highly amphiphobic porous materials. Methods of making and using the amphiphobic porous materials are also provided. |
| FILED | Friday, January 05, 2018 |
| APPL NO | 16/475711 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/226 (20130101) B01J 20/0244 (20130101) Non-metallic Elements; Compounds Thereof; C01B 39/52 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 3/06 (20130101) Original (OR) Class Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/36 (20130101) C08J 2300/102 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 30/00 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407786 | Lu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Zheng-Rong Lu (Beachwood, Ohio); Amita M. Vaidya (Cleveland Heights, Ohio) |
| ABSTRACT | A nanosized complex includes siRNA and a compound comprising formula (I): |
| FILED | Monday, September 30, 2019 |
| APPL NO | 16/588362 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 5/0606 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 2310/14 (20130101) C12N 2310/3513 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
11407851 — Chemically modified shape memory polymer embolic foams with increased X-ray visualization
| US 11407851 | Nash et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | Landon D. Nash (Sunnyvale, California); Kendal P. Ezell (Tomball, Texas) |
| ABSTRACT | An embodiment includes a system comprising: an iodine containing thermoset open-cell shape memory polymer (SMP) foam that is x-ray visible; wherein (a) the SMP foam is configured to expand from a compressed secondary state to an expanded primary state in response to thermal stimulus, (b) the SMP foam is a poly(urethane-urea-amide). Other embodiments are described herein. |
| FILED | Friday, December 01, 2017 |
| APPL NO | 16/465555 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/73 (20130101) C08G 18/3206 (20130101) C08G 18/3215 (20130101) C08G 18/3275 (20130101) Original (OR) Class C08G 18/3821 (20130101) C08G 18/3897 (20130101) C08G 18/5018 (20130101) C08G 2110/005 (20210101) C08G 2280/00 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/08 (20130101) C08K 5/52 (20130101) C08K 5/0066 (20130101) C08K 7/02 (20130101) C08K 2003/0887 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407855 | Guironnet et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Damien S. Guironnet (Urbana, Illinois); Danielle Harrier (Urbana, Illinois); Paul Kenis (Champaign, Illinois) |
| ABSTRACT | We have developed a ring opening polymerization method in an aqueous dispersion for the formation of latex. By encapsulating a catalyst in micelles dispersed in water, a seeded catalytic polymerization of various monomers in water was successfully performed. An amphiphilic molecule was used to form a micelle with a hydrophobic core in water. The catalyst that was encapsulated within this structure and the formed microcapsules were used as microreactors for the formation of biodegradable elastomers. |
| FILED | Wednesday, August 19, 2020 |
| APPL NO | 16/997296 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407979 | Khetani et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| ASSIGNEE(S) | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colorado) |
| INVENTOR(S) | Salman R. Khetani (Chicago, Illinois); Matthew D. Davidson (Philadelphia, Pennsylvania) |
| ABSTRACT | The present disclosure relates to compositions and methods for culturing a population of hepatocytes in vitro, comprising co-culturing the population of hepatocytes with at least one non-parenchymal cell population and incubating the co-culture in culture medium, wherein the co-culture is periodically incubated in culture medium that does not comprise serum (serum-free culture medium). |
| FILED | Friday, August 31, 2018 |
| APPL NO | 16/119399 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/067 (20130101) Original (OR) Class C12N 2500/34 (20130101) C12N 2500/90 (20130101) C12N 2502/02 (20130101) C12N 2502/1323 (20130101) C12N 2503/00 (20130101) C12N 2533/54 (20130101) C12N 2535/00 (20130101) C12N 2535/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5014 (20130101) G01N 33/5067 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11408014 | Pfleger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Brian F. Pfleger (Madison, Wisconsin); Nestor Hernandez-Lozada (Jena, Germany); Rung-Yi Lai (Changhua, Taiwan) |
| ABSTRACT | Mutant thioesterases having enhanced medium chain substrate activity, polynucleotides encoding and configured to express the mutant thioesterases in a transformed host cell, host cells transformed to contain the polynucleotides, and methods of using same. |
| FILED | Thursday, October 15, 2020 |
| APPL NO | 17/071376 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) C12N 15/52 (20130101) C12N 15/70 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/6409 (20130101) Original (OR) Class Enzymes C12Y 301/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11408030 | Madrid et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Andy Madrid (Madison, Wisconsin); Reid Spencer Alisch (Prairie du Sac, Wisconsin); Kirk Jeffrey Hogan (Madison, Wisconsin) |
| ASSIGNEE(S) | Andy Madrid (Madison, Wisconsin); Reid Spencer Alisch (Prairie du Sac, Wisconsin); Kirk Jeffrey Hogan (Madison, Wisconsin) |
| INVENTOR(S) | Andy Madrid (Madison, Wisconsin); Reid Spencer Alisch (Prairie du Sac, Wisconsin); Kirk Jeffrey Hogan (Madison, Wisconsin) |
| ABSTRACT | Provided herein is technology for Alzheimer's disease testing and particularly, but not exclusively, methods, compositions, and related uses for detecting the presence of Alzheimer's disease. |
| FILED | Monday, September 09, 2019 |
| APPL NO | 16/564948 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class C12Q 2600/154 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11408096 | Lozano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Karen Lozano (McAllen, Texas); Yuanbing Mao (McAllen, Texas); Carlos Hernandez (Hildalgo, Texas); Misael E. Martinez (McAllen, Texas); Mark Anthony Ruiz (McAllen, Texas); Jorge Ernesto Vidal (McAllen, Texas); Jose Zuniga (McAllen, Texas) |
| ABSTRACT | Described herein is the application of centrifugal spinning to provide a flexible mechanoluminescent material composed of rare earth metal doped fibers. Rare earth metal doped fibers are formed, in one embodiment, by centrifugal spinning. |
| FILED | Friday, September 07, 2018 |
| APPL NO | 16/644686 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2027/14 (20130101) B29K 2027/16 (20130101) B29K 2505/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/025 (20130101) C09K 11/7713 (20130101) C09K 11/7715 (20130101) C09K 11/7727 (20130101) C09K 11/7728 (20130101) C09K 11/7741 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/18 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 1/10 (20130101) Original (OR) Class D01F 6/12 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2321/042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11408850 | Xiao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yi Xiao (Miami, Florida); Juan Canoura (Hialeah Gardens, Florida) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida) |
| INVENTOR(S) | Yi Xiao (Miami, Florida); Juan Canoura (Hialeah Gardens, Florida) |
| ABSTRACT | The subject invention provides materials and methods for single-step fluorescence and electrochemical detection of small molecules, e.g., fentanyl and its analogs, in a sample. The subjection invention provides nucleic acids materials, e.g., aptamers (nucleic acid oligonucleotides) that can bind to fentanyl and its analogs with nanomolar affinity and high specificity against illicit drugs, adulterants, and cutting agents commonly existing in seized samples. The method for detecting fentanyl and/or its analogs in a sample comprises contacting the sample with an aptamer-based sensor selective for fentanyl and its analogs, and sensitively, specifically, and rapidly detecting fentanyl and/or its analogs in the sample. |
| FILED | Tuesday, June 22, 2021 |
| APPL NO | 17/354342 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) C12N 2310/16 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 27/3276 (20130101) Original (OR) Class G01N 27/3277 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11408880 | Wanunu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northeastern University (Boston, United Kingdom); University of York (York, United Kingdom) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts); University of York (Heslington, United Kingdom) |
| INVENTOR(S) | Meni Wanunu (Needham, Massachusetts); Alfred Antson (York, United Kingdom); Sandra Greive (York, United Kingdom); Benjamin Cressiot (Montlignon, France) |
| ABSTRACT | Hybrid nanopores, comprising a protein pore supported within a solid-state membrane, which combine the robust nature of solid-state membranes with the easily tunable and precise engineering of protein nanopores. In an embodiment, a lipid-free hybrid nanopore comprises a water soluble and stable, modified portal protein of the Thermus thermophilus bacteriophage G20c, electrokinetically inserted into a larger nanopore in a solid-state membrane. The hybrid pore is stable and easy to fabricate, and exhibits low peripheral leakage, allowing sensing and discrimination among different types of biomolecules. |
| FILED | Friday, May 17, 2019 |
| APPL NO | 16/416139 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 1/002 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2795/00022 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/48721 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 930/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11408885 | Ahrens et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Caroline Chopko Ahrens (Kennett Square, Pennsylvania); Linda G. Griffith (Cambridge, Massachusetts); Steven Robert Tannenbaum (Brookline, Massachusetts); Christi Dionne Cook (Cambridge, Massachusetts); Ravindra Kodihalli (Acton, Massachusetts); Douglas A. Lauffenburger (Cambridge, Massachusetts); Evan L. Chiswick (Jamaica Plain, Massachusetts); Miles Miller (Cambridge, Massachusetts) |
| ABSTRACT | Proteases regulate a wide range of normal cellular functions where dysregulated activity is observed in various diseases. Compositions and methods use protease activity multiplexed bead-based immunoassays to profile protease activity. This platform technology integrates protease activity measurements with total protein quantification techniques. It represents a significant improvement over existing detection techniques by allowing for multiplexed, sensitive active protease measurements in complex biological samples. Exemplary multiplexed detections are realized in a single assay using a minute sample amount (e.g., 5 μl) for active recombinant MMP-1, -2, -3, -7, 9, and 12 and those same MMPs in cell culture supernatant, menstrual fluid effluent, and peritoneal aspirates. This multiplexed platform achieves high level of sensitivities equal to or better than existing leading single-plex detection strategies. It also allows for high throughput screening to identify inhibitors of proteases in complex, donor-derived samples. |
| FILED | Tuesday, August 28, 2018 |
| APPL NO | 16/115289 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/37 (20130101) Enzymes C12Y 304/24007 (20130101) C12Y 304/24024 (20130101) C12Y 304/24035 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/58 (20130101) G01N 33/533 (20130101) G01N 33/535 (20130101) G01N 33/573 (20130101) Original (OR) Class G01N 33/574 (20130101) G01N 33/54306 (20130101) G01N 33/54313 (20130101) G01N 33/54326 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 99/00 (20190201) Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 99/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11408893 | Martinic et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (Paris, France) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); Centre National De La Recherche Scientifique (Paris, France) |
| INVENTOR(S) | Ivana Martinic (Orléans, France); Tu Ngoc Nguyen (Ann Arbor, Michigan); Svetlana V. Eliseeva (Orléans, France); Vincent L. Pecoraro (Ann Arbor, Michigan); Stéphane Petoud (Orléans, France) |
| ABSTRACT | A method for selective labelling of necrotic cells including incubating the cells in a solution including a Ln(III)Zn16(HA ligand)16 metallacrown complex, wherein the HA ligand is a hydroximate ligand. |
| FILED | Wednesday, August 21, 2019 |
| APPL NO | 16/547396 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 3/06 (20130101) C07F 5/003 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) G01N 21/33 (20130101) G01N 21/6458 (20130101) G01N 33/583 (20130101) Original (OR) Class G01N 2001/302 (20130101) G01N 2001/305 (20130101) G01N 2021/6439 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11408959 | Brandt-Pearce et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia); Maite Brandt-Pearce (Free Union, Virginia); Hamid Hosseinianfar (Charlottesville, Virginia); Mohammad Noshad (Charlottesville, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Maite Brandt-Pearce (Free Union, Virginia); Hamid Hosseinianfar (Charlottesville, Virginia); Mohammad Noshad (Charlottesville, Virginia) |
| ABSTRACT | A positioning system and method includes a transmitter, a receiver, and a controller. The transmitter includes at least one energy source configured to emit an optical or quasi-optical electromagnetic signal as a channel communication. The receiver includes at least one detector element configured to receive the channel communication. The controller is connected to the receiver and configured to estimate a position of the transmitter within a space using a reference map of the space and one or more diffuse components of an impulse response of the channel communication. |
| FILED | Friday, December 21, 2018 |
| APPL NO | 16/956712 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 1/70 (20130101) Original (OR) Class G01S 5/16 (20130101) Transmission H04B 10/11 (20130101) H04B 10/69 (20130101) H04B 10/114 (20130101) H04B 10/502 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 25/0212 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11409526 | Siskind et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana); NATIONAL UNIVERSITY OF IRELAND, MAYNOOTH (Maynooth, Ireland) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Jeffrey Mark Siskind (West Lafayette, Indiana); Barak Avrum Pearlmutter (Dublin, Ireland) |
| ABSTRACT | A system and method which allows the basic checkpoint-reverse-mode AD strategy (of recursively decomposing the computation to reduce storage requirements of reverse-mode AD) to be applied to arbitrary programs: not just programs consisting of loops, but programs with arbitrarily complex control flow. The method comprises (a) transforming the program into a formalism that allows convenient manipulation by formal tools, and (b) introducing a set of operators to allow computations to be decomposed by running them for a given period of time then pausing them, while treating the paused program as a value subject to manipulation. |
| FILED | Wednesday, September 13, 2017 |
| APPL NO | 16/336094 |
| ART UNIT | 2181 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 7/60 (20130101) G06F 7/544 (20130101) G06F 9/461 (20130101) G06F 9/30036 (20130101) Original (OR) Class G06F 11/36 (20130101) G06F 17/10 (20130101) G06F 17/13 (20130101) G06F 17/17 (20130101) Computer Systems Based on Specific Computational Models G06N 5/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11409619 | Gopalan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| INVENTOR(S) | Kartik Gopalan (Vestal, New York); Ping Yang (Vestal, New York); Dinuni K. Fernando (Kandana, Sri Lanka); Jonathan Terner (Beacon, New York) |
| ABSTRACT | Post-copy is one of the two key techniques (besides pre-copy) for live migration of virtual machines in data centers. Post-copy provides deterministic total migration time and low downtime for write-intensive VMs. However, if post-copy migration fails for any reason, the migrating VM is lost because the VM's latest consistent state is split between the source and destination nodes during migration. PostCopyFT provides a new approach to recover a VM after a destination or network failure during post-copy live migration using an efficient reverse incremental checkpointing mechanism. PostCopyFT was implemented and evaluated in the KVM/QEMU platform. Experimental results show that the total migration time of post-copy remains unchanged while maintaining low failover time, downtime, and application performance overhead. |
| FILED | Wednesday, April 28, 2021 |
| APPL NO | 17/242508 |
| ART UNIT | 2113 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 11/301 (20130101) G06F 11/0772 (20130101) G06F 11/0793 (20130101) G06F 11/1471 (20130101) G06F 11/1484 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11409630 | Shao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Zhong Shao (Branford, Connecticut); Ronghui Gu (New Haven, Connecticut); Vilhelm Sjoberg (New Haven, Connecticut); Jieung Kim (New Haven, Connecticut); Jeremie Koenig (New Haven, Connecticut) |
| ABSTRACT | Systems and methods for formal verification of programs. The systems and methods provide a new game-theoretical, strategy-based compositional semantic model for concurrency, a set of formal linking theorems for composing multithreaded and multicore concurrent layers, and a compiler that supports certified thread-safe compilation and linking. Verification of an overlay interface can include determining an intermediate strategy for a primitive operation running on an underlay interface and refining that intermediate strategy to a strategy running on the overlay interface by applying a vertical and a horizontal composition rule. The refined strategy can then be composed with compatible strategies running on the overlay interface according to a parallel composition rule. Strategies may be compatible when rely conditions imposed by each strategy satisfy guarantees provided by the other strategies. The system and method of formal verification can be applied to formal verification of smart contracts. |
| FILED | Wednesday, November 28, 2018 |
| APPL NO | 16/767569 |
| ART UNIT | 2198 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 11/3608 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11409802 | Miranker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | data.world, Inc. (Austin, Texas) |
| ASSIGNEE(S) | data.world, Inc. (Austin, Texas) |
| INVENTOR(S) | Daniel Paul Miranker (Austin, Texas); Juan Federico Sequeda (Austin, Texas) |
| ABSTRACT | The invention is a system for integrating data sets organized in one organization type with data sets organized in a second organization type so that data queries submitted to be processed in the manner of the first organization type can be translated into queries usable by the data set in the second data organization type and the results returned to satisfy the first query. |
| FILED | Monday, December 07, 2020 |
| APPL NO | 17/114385 |
| ART UNIT | 2157 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/25 (20190101) G06F 16/81 (20190101) G06F 16/86 (20190101) G06F 16/353 (20190101) G06F 16/8358 (20190101) G06F 16/8365 (20190101) G06F 16/90332 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11409814 | Clauset et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado (Denver, Colorado) |
| INVENTOR(S) | Aaron Clauset (Louisville, Colorado); Allison C. Morgan (Boulder, Colorado); Samuel F. Way (Boulder, Colorado) |
| ABSTRACT | Embodiments herein provide for a more efficient web crawler (102) that accesses a plurality of links from a web page (106). In certain embodiments, the web crawler (102) determines link scores for each of the plurality of links, with each link score corresponding to a probability that the associated link leads to a web page (106) of a target page type. The plurality of links and the associated link scores are added to a priority queue (114). The web crawler (102) accesses a second web page (106) using the highest-ranked link in the priority queue (114), obtains links from that web page (106), identifies a link score for each of those links, and adds those links to the priority queue (114) based on their link scores. This process can be repeated for several pages, as needed, using the highest-rank link in each instance, until the crawler (102) identifies a web page (106) of a target page type. |
| FILED | Thursday, November 29, 2018 |
| APPL NO | 16/768420 |
| ART UNIT | 2161 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/951 (20190101) Original (OR) Class G06F 40/205 (20200101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6267 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11410360 | Ruth et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| INVENTOR(S) | Kimberly C. Ruth (Seattle, Washington); Tadayoshi Kohno (Seattle, Washington); Franziska Roesner (Seattle, Washington) |
| ABSTRACT | In some embodiments, a method of providing visual cues for private virtual objects is provided. In response to determining that presentation of a protected characteristic of a virtual object is not permitted by an augmented reality system, the augmented reality system presents a placeholder object. In some embodiments, a method of protecting a location from undesirable virtual objects is provided. In response to determining that a location for a virtual object is associated with a protected location, a low-invasiveness version of a mesh of the virtual object is presented. In some embodiments, a method of decoupling a virtual object from a static physical location is provided. |
| FILED | Friday, May 15, 2020 |
| APPL NO | 16/875833 |
| ART UNIT | 2616 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 21/604 (20130101) G06F 21/6218 (20130101) Image Data Processing or Generation, in General G06T 11/001 (20130101) G06T 11/60 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11410746 | Veneziano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Remi Veneziano (Allston, Massachusetts); Sakul Ratanalert (Cambridge, Massachusetts); Tyson Shepherd (Arlington, Massachusetts); Hyungmin Jun (Arlington, Massachusetts); Mark Bathe (Cambridge, Massachusetts) |
| ABSTRACT | Methods for the top-down design of nucleic acid nanostructures of arbitrary geometry based on target shape of spherical or non-spherical topology are described. The methods facilitate 3D molecular programming of lipids, proteins, sugars, and RNAs based on a DNA scaffold of arbitrary 2D or 3D shape. Geometric objects are rendered as node-edge networks of parallel nucleic acid duplexes, and a nucleic acid scaffold routed throughout the network using a spanning tree formula. Nucleic acid nanostructures produced according to top-down design methods are also described. In some embodiments, the nanostructures include single-stranded nucleic acid scaffold, DX crossovers, and staple strands. In other embodiments, the nanostructures include single-stranded nucleic acid scaffold, PX crossovers and no staples. Modified nanostructures include chemically modified nucleotides and conjugated to other molecules are described. |
| FILED | Thursday, April 27, 2017 |
| APPL NO | 16/097596 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/26 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/10 (20130101) C12N 15/11 (20130101) C12N 2320/32 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 15/00 (20190201) Original (OR) Class G16B 15/10 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11410931 | Coffey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida); The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | University of Central Florida Research Founation, Inc. (Orlando, Florida); The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Kevin R. Coffey (Oviedo, Florida); Edward Dein (Saint Cloud, Florida); Sameer Ezzat (Mosul, Iraq); Prabhu Doss Mani (Memphis, Tennessee); Katayun Barmak (Elmsford, New York) |
| ABSTRACT | Crystallographic orientations of ruthenium films and related methods are disclosed. Single crystal ruthenium films are provided with crystallographic orientations that arrange a c-axis of the ruthenium crystal structure in a direction that corresponds with a plane of the film or along a direction that corresponds with a surface of a substrate on which the film is formed. While ruthenium films typically form with the c-axis perpendicular to the surface of the substrate or as a polycrystalline film with a random crystallographic orientation, substrate surfaces may be configured with a crystallographic surface net that promotes non-perpendicular c-axis orientations of ruthenium. The substrate may be formed with a metal-terminated surface in certain arrangements. In this regard, ruthenium films may be configured as metallic interconnects for devices where directions of lowest electrical resistivity within the crystal structure are arranged to correspond with the direction of current flow in the devices. |
| FILED | Tuesday, June 09, 2020 |
| APPL NO | 16/896356 |
| ART UNIT | 2819 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/32051 (20130101) H01L 23/528 (20130101) H01L 23/53214 (20130101) H01L 23/53257 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11411872 | Rahouti et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Mohamed Rahouti (Tampa, Florida); Kaiqi Xiong (Tampa, Florida); Yufeng Xin (Tampa, Florida); Nasir Ghani (Tampa, Florida) |
| ABSTRACT | The centralized control capability of Software Defined Networking (SDN) presents a unique opportunity for enabling Quality of Service (QoS) routing. For delay sensitive traffic flows, a QoS mechanism efficiently computes path latency and minimizes a controller's response time. At the core of the challenges is how to handle short term network state fluctuations in terms of congestion and latency while guaranteeing the end-to-end latency performance of networking services. The disclosed technology provides a systematic framework that considers active link latency measurements, efficient statistic estimate of network states, and fast adaptive path computation. The disclosed technology can be implemented, for example, as an SDN controller application, and can find optimal end-to-end paths with minimum latency and significantly reduce the control overhead. |
| FILED | Tuesday, October 13, 2020 |
| APPL NO | 17/069844 |
| ART UNIT | 2462 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 45/02 (20130101) H04L 47/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11406401 | Szafron et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California); The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California); The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | Jason Szafron (Hamden, Connecticut); Duncan Maitland (College Station, Texas); Ward Small, IV (Livermore, California); Patrick R. Buckley (Livermore, California); Andrea D. Muschenborn (Bloomington, Indiana) |
| ABSTRACT | An embolectomy device comprised of an expansion unit and a support unit is disclosed. The expansion unit can be actuated in response to one or more external stimuli, and the support unit, located proximately to the expansion unit, provides a force to hold the expansion unit in place and to further induce the expansion unit's radial expansion. The radial expansion of the expansion unit causes the expansion unit to physically contact a blood clot, enabling the blood clot to be removed. In some embodiments, the expansion unit can be fabricated from a shape memory polymer foam. In some embodiments the support unit can be fabricated from any elastic material including, without limitation, shape memory alloys. |
| FILED | Tuesday, December 03, 2019 |
| APPL NO | 16/701417 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/22 (20130101) Original (OR) Class A61B 2017/00526 (20130101) A61B 2017/00867 (20130101) A61B 2017/00871 (20130101) A61B 2017/2212 (20130101) A61B 2017/22094 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406960 | Yacout et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Abdellatif M. Yacout (Naperville, Illinois); Sumit Bhattacharya (Darien, Illinois); Yinbin Miao (Aurora, Illinois) |
| ABSTRACT | An adsorptive material for adsorption of a noble gas can include a mesoporous support material having a plurality of pores and a pattern of metal atoms deposited onto the mesoporous support material. |
| FILED | Thursday, September 26, 2019 |
| APPL NO | 16/583851 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/02 (20130101) B01D 2253/25 (20130101) B01D 2253/106 (20130101) B01D 2253/1122 (20130101) B01D 2257/11 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/183 (20130101) Original (OR) Class B01J 20/0225 (20130101) B01J 20/3078 (20130101) B01J 20/3204 (20130101) B01J 20/3225 (20130101) B01J 20/3236 (20130101) B01J 20/28064 (20130101) B01J 20/28083 (20130101) B01J 20/28097 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406961 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| INVENTOR(S) | Jing Li (Cranbury, New Jersey); Baiyan Li (East Brunswick, New Jersey) |
| ABSTRACT | Novel radioactive iodide molecular traps, in which one or more metal atoms are functionalized by coordinating to an amine containing two or more nitrogens, and methods of using the molecular traps to capture radioactive iodide. |
| FILED | Friday, December 29, 2017 |
| APPL NO | 16/472987 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/02 (20130101) B01D 2253/31 (20130101) B01D 2253/204 (20130101) B01D 2253/306 (20130101) B01D 2253/308 (20130101) B01D 2257/2068 (20130101) B01D 2259/40083 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/226 (20130101) Original (OR) Class B01J 20/2808 (20130101) B01J 20/3425 (20130101) B01J 20/3475 (20130101) B01J 20/28066 (20130101) B01J 20/28083 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406971 | Luz Minguez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RESEARCH TRIANGLE INSTITUTE (Research Triangle Park, North Carolina) |
| ASSIGNEE(S) | Research Triangle Institute (Research Triangle Park, North Carolina) |
| INVENTOR(S) | Ignacio Luz Minguez (Durham, North Carolina); Mustapha Soukri (Cary, North Carolina); Marty Lail (Raleigh, North Carolina); John R Carpenter (Apex, North Carolina); Sameer Parvathikar (Raleigh, North Carolina); Michael Carpenter (Raleigh, North Carolina) |
| ABSTRACT | The present disclosure provides methods of making confined nanocatalysts within mesoporous materials (MPMs). The methods utilize solid state growth of nanocrystalline metal organic frameworks (MOFs) followed by controlled transformation to generate nanocatalysts in situ within the mesoporous material. The disclosure also provides applications of the nanocatalysts to a wide variety of fields including, but not limited to, liquid organic hydrogen carriers, synthetic liquid fuel preparation, and nitrogen fixation. |
| FILED | Tuesday, March 26, 2019 |
| APPL NO | 17/041944 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 29/035 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 1/12 (20130101) C07F 5/00 (20130101) C07F 5/061 (20130101) C07F 7/00 (20130101) C07F 7/28 (20130101) C07F 9/00 (20130101) C07F 11/00 (20130101) C07F 15/00 (20130101) C07F 15/02 (20130101) C07F 15/04 (20130101) C07F 15/006 (20130101) C07F 15/06 (20130101) C07F 15/0033 (20130101) C07F 15/0046 (20130101) C07F 15/0073 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407663 | Campbell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Patrick G. Campbell (Oakland, California); Jennifer M. Knipe (Oakland, California); Michael Stadermann (Pleasanton, California) |
| ABSTRACT | Disclosed here is a capacitive deionization device for removing ions from a target solution. The capacitive deionization device includes a first porous electrode, a second porous electrode, a first header plate, a second header plate, and a sealant. The second porous electrode is disposed below and spaced from the first porous electrode. The first header plate is disposed on the first porous electrode. The first header plate defines an input flow channel that is in fluidic communication with the first porous electrode. The second header plate is disposed below the second porous electrode. The second header plate defines an output flow channel that is in fluidic communication with the second porous electrode. The sealant is disposed between the first header plate and the second header plate and surrounds the first porous electrode and the second porous electrode. |
| FILED | Friday, November 10, 2017 |
| APPL NO | 15/809864 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/4691 (20130101) Original (OR) Class C02F 1/46109 (20130101) C02F 2001/46161 (20130101) C02F 2103/08 (20130101) C02F 2201/46115 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/02 (20130101) H01G 9/10 (20130101) H01G 9/12 (20130101) H01G 9/0029 (20130101) H01G 9/048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407792 | Silberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WILLIAM MARSH RICE UNIVERSITY (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Jonathan Silberg (Houston, Texas); Joshua T. Atkinson (Houston, Texas); Ian J. Campbell (Houston, Texas); George N. Bennett (Houston, Texas) |
| ABSTRACT | Engineered protein electron carriers, microorganisms expressing the same, and methods detecting regulated electron flow are described. |
| FILED | Friday, November 09, 2018 |
| APPL NO | 16/186226 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/21 (20130101) Original (OR) Class C07K 14/415 (20130101) C07K 2319/00 (20130101) C07K 2319/73 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/542 (20130101) G01N 33/566 (20130101) G01N 2333/79 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407946 | Elliott et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Douglas C. Elliott (Richland, Washington); Gary G. Neuenschwander (Burbank, Washington); Todd R. Hart (Kennewick, Washington) |
| ABSTRACT | A combined hydrothermal liquefaction (HTL) and catalytic hydrothermal gasification (CHG) system and process are described that convert various biomass-containing sources into separable bio-oils and aqueous effluents that contain residual organics. Bio-oils may be converted to useful bio-based fuels and other chemical feedstocks. Residual organics in HTL aqueous effluents may be gasified and converted into medium-BTU product gases and directly used for process heating or to provide energy. |
| FILED | Friday, November 02, 2018 |
| APPL NO | 16/179495 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Destructive Distillation of Carbonageous Materials for Production of Gas, Coke, Tar, or Similar Materials C10B 49/16 (20130101) Original (OR) Class Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 1/06 (20130101) C10G 1/065 (20130101) C10G 3/40 (20130101) C10G 3/50 (20130101) Production of Producer Gas, Water-gas, Synthesis Gas From Solid Carbonaceous Material, or Mixtures Containing These Gases; Carburetting Air or Other Gases C10J 3/00 (20130101) C10J 2200/06 (20130101) C10J 2300/0916 (20130101) C10J 2300/0973 (20130101) C10J 2300/1681 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 3/08 (20130101) C10L 9/08 (20130101) C10L 9/086 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/10 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/145 (20151101) Y02P 30/20 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11408013 | Lynch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CARGILL, INCORPORATED (Wayzata, Minnesota) |
| ASSIGNEE(S) | CARGILL, INCORPORATED (Wayzata, Minnesota) |
| INVENTOR(S) | Michael Lynch (Durham, North Carolina); Michael Louie (Broomfield, Colorado); Shelley Copley (Boulder, Colorado); Eileen Spindler (Lafayette, Colorado); Brittany Robinson (Wheat Ridge, Colorado); Matthew Lipscomb (Boulder, Colorado); Tanya Lipscomb-Warnecke (Boulder, Colorado); Hans Liao (Superior, Colorado); David Hogsett (Niwot, Colorado); Ron Evans (Louisville, Colorado) |
| ABSTRACT | This invention relates to metabolically engineered microorganism strains, such as bacterial strains, in which there is an increased utilization of malonyl-CoA for production of a fatty acid or fatty acid derived product, wherein the modified microorganism produces fatty acyl-CoA intermediates via a malonyl-CoA dependent but malonyl-ACP independent mechanism. |
| FILED | Wednesday, June 26, 2019 |
| APPL NO | 16/453323 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 9/001 (20130101) C12N 9/0006 (20130101) C12N 9/88 (20130101) C12N 9/1029 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/6409 (20130101) Original (OR) Class Enzymes C12Y 101/01035 (20130101) C12Y 103/01093 (20150701) C12Y 203/01194 (20130101) C12Y 402/01059 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11408074 | Lepro Chavez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Xavier N. Lepro Chavez (Dublin, California); Chantel M. Aracne-Ruddle (Livermore, California); Salmaan H. Baxamusa (Livermore, California); Michael Stadermann (Pleasanton, California) |
| ABSTRACT | Provided herein is a nanoscale material assembly made up of a plurality of nanoscale structures with a crosslinked polymer thermally deposited on the structures. Also disclosed are methods for preparing the nanoscale material assembly with a deposited crosslinked polymer. Further disclosed are various conditions and materials that when used in the preparation of the nanoscale material assemblies further enhance their mechanical properties. In some embodiments, the nanoscale material assemblies can be either nanoscale yarn assemblies or nanoscale sheet assemblies. |
| FILED | Wednesday, January 10, 2018 |
| APPL NO | 15/867581 |
| ART UNIT | 1783 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/60 (20130101) B05D 1/62 (20130101) B05D 3/007 (20130101) B05D 3/067 (20130101) B05D 2203/35 (20130101) B05D 2256/00 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 70/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/56 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
11408683 — Heat transfer device having an enclosure and a non-permeable barrier inside the enclosure
| US 11408683 | Shaeri et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ADVANCED COOLING TECHNOLOGIES, INC. (Lancaster, Pennsylvania) |
| ASSIGNEE(S) | Advanced Cooling Technologies, Inc. (Lancaster, Pennsylvania) |
| INVENTOR(S) | Mohammad Reza Shaeri (Lancaster, Pennsylvania); Richard W. Bonner, III (Lancaster, Pennsylvania); Michael C. Ellis (Lancaster, Pennsylvania); Elizabeth K. Seber (Lancaster, Pennsylvania); Maksym V. Demydovych (Lancaster, Pennsylvania) |
| ABSTRACT | A heat transfer device includes a hollow spacer between opposed substrates, defining an enclosure, at least one of the substrates adapted to be secured to at least one heat source. A non-permeable barrier is in the enclosure between the substrates. A first chamber inside the enclosure is defined by the spacer, the substrates, and the barrier, the first chamber in fluid communication with at least one first inlet and first outlet. A second chamber inside the enclosure and outside the first chamber and is defined by the spacer, the substrates, and the barrier, the second chamber in fluid communication with at least one second outlet. A wick structure is secured to at least one substrate, a first portion of the wick structure in the first chamber, and a second portion of the wick structure in the second chamber and interconnecting in passive liquid communication with the first portion. |
| FILED | Wednesday, August 26, 2020 |
| APPL NO | 17/003539 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/025 (20130101) F28D 15/046 (20130101) F28D 15/0266 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11408827 | Ohodnicki, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Department of Energy (Washington, District of Columbia) |
| ASSIGNEE(S) | U.S. Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Paul R. Ohodnicki, Jr. (Allison Park, Pennsylvania); Congjun Wang (Bethel Park, Pennsylvania); Thomas D. Brown (Finleyville, Pennsylvania); Barbara Kutchko (Upper St Clair, Pennsylvania) |
| ABSTRACT | A method for evaluating the pH of an aqueous solution by utilizing the optical properties of a pH sensing material comprised of plurality of optically active nanoparticles dispersed in matrix material. The optically active nanoparticles have an electronic conductivity greater than about 10−1 S/cm and generally have an average nanoparticle diameter of less that about 500 nanometers, and the matrix material is a material which experiences a change in surface charge density over a pH range from 2.0 to 12.0 of at least 1%. The method comprises contacting the pH sensing material and the aqueous solution, illuminating the pH sensing material, and monitoring an optical signal generated through comparison of incident light and exiting light to determine the optical transmission, absorption, reflection, and/or scattering of the pH sensitive material. The optical signal of the pH sensitive material varies in response to the pH of the aqueous solution. |
| FILED | Friday, April 24, 2015 |
| APPL NO | 14/695078 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/31 (20130101) G01N 21/49 (20130101) G01N 21/84 (20130101) Original (OR) Class G01N 2201/063 (20130101) G01N 2201/0826 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11409011 | Hu |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Advanced Geophysical Technology Inc. (Houston, Texas) |
| ASSIGNEE(S) | Advanced Geophysical Technology Inc. (Houston, Texas) |
| INVENTOR(S) | Wenyi Hu (Houston, Texas) |
| ABSTRACT | A computer-implemented method for obtaining reconstructed seismic data for determining a subsurface feature, includes: determining an initial training velocity model, training a machine learning model based on first training seismic data and second training seismic data generated from the training velocity model, the first training seismic data corresponding to one or more first frequencies, the second training seismic data corresponding to one or more second frequencies lower than the one or more first frequencies, obtaining, based on measured seismic data and the machine learning model, reconstructed seismic data corresponding to the one or more second frequencies, generating a velocity model based on the measured seismic data, the reconstructed seismic data, and a full waveform inversion (FWI), and when the generated velocity model does not satisfy a preset condition, updating the training velocity model based on the generated velocity model, to obtain updated reconstructed seismic data for determining a subsurface feature. |
| FILED | Wednesday, July 08, 2020 |
| APPL NO | 16/923525 |
| ART UNIT | 2865 — Printing/Measuring and Testing |
| CURRENT CPC | Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 1/282 (20130101) Original (OR) Class G01V 1/303 (20130101) G01V 2210/673 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11409183 | Gehl et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Michael Gehl (Albuquerque, New Mexico); Christopher Michael Long (Albuquerque, New Mexico) |
| ABSTRACT | A method and apparatus are provided for controlling the phase shifts produced in a binary corporate tree network of the kind, e.g., that can drive a phased array for steering an optical beam. The method employs a novel phase-wrapping technique in which an entire layer of the binary tree is disabled when the phase added in that layer reaches 2π. With that technique, it is possible to economize on electrical control lines and on the use of electric power, while still maintaining the ability to produce arbitrary phases at the output of the tree network. |
| FILED | Tuesday, February 23, 2021 |
| APPL NO | 17/182883 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/2955 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11409597 | Sullivan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NVIDIA Corp. (Santa Clara, California) |
| ASSIGNEE(S) | NVIDIA Corp. (Santa Clara, California) |
| INVENTOR(S) | Michael Sullivan (Austin, Texas); Siva Hari (Sunnyvale, California); Brian Zimmer (Palo Alto, California); Timothy Tsai (Santa Clara, California); Stephen W. Keckler (Austin, Texas) |
| ABSTRACT | An error reporting system utilizes a parity checker to receive data results from execution of an original instruction and a parity bit for the data. A decoder receives an error correcting code (ECC) for data resulting from execution of a shadow instruction of the original instruction, and data error correction is initiated on the original instruction result on condition of a mismatch between the parity bit and the original instruction result, and the decoder asserting a correctable error in the original instruction result. |
| FILED | Friday, March 06, 2020 |
| APPL NO | 16/811499 |
| ART UNIT | 2114 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 9/30029 (20130101) G06F 9/30116 (20130101) G06F 11/102 (20130101) Original (OR) Class G06F 11/0772 (20130101) G06F 11/1044 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11409887 | Gourisetti et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington); Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
| INVENTOR(S) | Sri Nikhil Gupta Gourisetti (Richland, Washington); Michael E. Mylrea (Alexandria, Virginia); Hirak Patangia (Little Rock, Arkansas) |
| ABSTRACT | Systems, methods, and computer media for mitigating cybersecurity vulnerabilities of systems are provided herein. A current cybersecurity maturity of a system can be determined based on maturity criteria. The maturity criteria can be ranked based on importance. Solution candidates for increasing the cybersecurity maturity of the system can be determined based on the ranking. The solution candidates specify cybersecurity levels for the maturity criteria. A present state value reflecting the current cybersecurity maturity of the system can be calculated. For the solution candidates, an implementation state value and a transition state value can be determined. The implementation state value represents implementation of the maturity levels of the solution candidate, and the transition state value represents a transition from the present state value to the implementation state value. Based on the transition state values, a solution candidate can be selected for the system, and the system can be modified accordingly. |
| FILED | Thursday, May 07, 2020 |
| APPL NO | 16/869378 |
| ART UNIT | 2436 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/577 (20130101) Original (OR) Class G06F 2221/034 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1433 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11409922 | Aimone et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | James Bradley Aimone (Albuquerque, New Mexico); William Mark Severa (Albuquerque, New Mexico); Richard B. Lehoucq (Albuquerque, New Mexico); Ojas D. Parekh (Albuquerque, New Mexico) |
| ABSTRACT | A method for increasing a speed or energy efficiency at which a computer is capable of modeling a plurality of random walkers. The method includes defining a virtual space in which a plurality of virtual random walkers will move among different locations in the virtual space, wherein the virtual space comprises a plurality of vertices and wherein the different locations are ones of the plurality of vertices. A corresponding set of neurons in a spiking neural network is assigned to a corresponding vertex such that there is a correspondence between sets of neurons and the plurality of vertices, wherein a spiking neural network comprising a plurality of sets of spiking neurons is established. A virtual random walk of the plurality of virtual random walkers is executed using the spiking neural network, wherein executing includes tracking how many virtual random walkers are at each vertex at a given time increment. |
| FILED | Wednesday, June 27, 2018 |
| APPL NO | 16/020627 |
| ART UNIT | 2122 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 30/20 (20200101) Original (OR) Class G06F 2111/10 (20200101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/049 (20130101) G06N 3/063 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11410782 | Subhash et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| INVENTOR(S) | Ghatu Subhash (Gainesville, Florida); Ronald Howard Baney (Gainesville, Florida); James S. Tulenko (Gainesville, Florida); Edward McKenna, III (Portland, Oregon); Lihao Ge (San Jose, California); Sunghwan Yeo (Gainesville, Florida) |
| ABSTRACT | Embodiments of the invention are directed to a method for production of a nuclear fuel pellet by spark plasma sintering (SPS), wherein a fuel pellet with more than 80% TD or more than 90% TD is formed. The SPS can be performed with the imposition of a controlled uniaxial pressure applied at the maximum temperature of the processing to achieve a very high density, in excess of 95% TD, at temperatures of 850 to 1600° C. The formation of a fuel pellet can be carried out in one hour or less. In an embodiment of the invention, a nuclear fuel pellet comprises UO2 and a highly thermally conductive material, such as SiC or diamond. |
| FILED | Tuesday, August 18, 2020 |
| APPL NO | 16/996715 |
| ART UNIT | 3619 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Nuclear Reactors G21C 3/045 (20190101) G21C 3/62 (20130101) G21C 3/64 (20130101) Original (OR) Class G21C 3/623 (20130101) G21C 21/02 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11410797 | Majkic et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | University of Houston System (Houston, Texas) |
| INVENTOR(S) | Goran Majkic (Houston, Texas); Venkat Selvamanickam (Houston, Texas) |
| ABSTRACT | An MOCVD system fabricates high quality superconductor tapes with variable thicknesses. The MOCVD system can include a gas flow chamber between two parallel channels in a housing. A substrate tape is heated and then passed through the MOCVD housing such that the gas flow is perpendicular to the tape's surface. Precursors are injected into the gas flow for deposition on the substrate tape. In this way, superconductor tapes can be fabricated with variable thicknesses, uniform precursor deposition, and high critical current densities. |
| FILED | Thursday, December 26, 2019 |
| APPL NO | 16/727326 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/0209 (20130101) C23C 16/408 (20130101) C23C 16/448 (20130101) C23C 16/545 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 12/06 (20130101) Original (OR) Class H01B 13/00 (20130101) H01B 13/008 (20130101) H01B 13/0026 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/2441 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11411154 | Ren et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| INVENTOR(S) | Zhifeng Ren (Pearland, Texas); Hangtian Zhu (Houston, Texas) |
| ABSTRACT | A ZrCoBi-based p-type half-Heusler material can have a formula: ZrCoBi1-x-ySnxSby, where x can vary between 0.01 and 0.25, and y can vary between 0 and 0.2. An average dimensionless figure-of-merit (ZT) for the material can be greater than or equal to about 0.80 as calculated by an integration method for temperatures between 300 and 973 K. A ZrCoBi-based n-type half-Heusler material can have a formula: ZrCo1-xNixBi1-ySby, where x can vary between 0.01 and 0.25, and y can vary between 0 and 0.3. The material has an average dimensionless figure-of-merit (ZT) is greater than or equal to about 0.65 as calculated by an integration method for temperatures between 300 and 973 K. |
| FILED | Wednesday, June 26, 2019 |
| APPL NO | 17/252659 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/02 (20130101) H01L 35/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11411212 | Yushin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sila Nanotechnologies Inc. (Alameda, California) |
| ASSIGNEE(S) | SILA NANOTECHNOLOGIES, INC. (Alameda, California) |
| INVENTOR(S) | Gleb Yushin (Atlanta, Georgia); Bogdan Zdyrko (Atlanta, Georgia); Addison Shelton (Atlanta, Georgia); Eugene Berdichevsky (Alameda, California); Igor Luzinov (Clemson, South Carolina); Alexander Jacobs (Oakland, California); Eerik Hantsoo (Oakland, California); George Gomes (Alameda, California) |
| ABSTRACT | A battery electrode composition is provided comprising composite particles, with each composite particle comprising active material and a scaffolding matrix. The active material is provided to store and release ions during battery operation. For certain active materials of interest, the storing and releasing of the ions causes a substantial change in volume of the active material. The scaffolding matrix is provided as a porous, electrically-conductive scaffolding matrix within which the active material is disposed. In this way, the scaffolding matrix structurally supports the active material, electrically interconnects the active material, and accommodates the changes in volume of the active material. |
| FILED | Thursday, March 10, 2022 |
| APPL NO | 17/691997 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/13 (20130101) H01M 4/38 (20130101) H01M 4/48 (20130101) H01M 4/139 (20130101) H01M 4/364 (20130101) Original (OR) Class H01M 4/366 (20130101) H01M 4/0402 (20130101) H01M 4/624 (20130101) H01M 4/625 (20130101) H01M 10/052 (20130101) H01M 10/054 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11411221 | Shi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Zhangxing Shi (Chicago, Illinois); Lu Zhang (Naperville, Illinois) |
| ABSTRACT | An electrode for a lithium-ion electrochemical cell comprises silicon particles and carbon particles coated on a conductive current collector. The silicon and carbon particles being bound to each other and to the current collector by a cross-linked binder formed from a combination of a poly(carboxylic acid) such as poly(acrylic acid) and a branched polyethyleneimine. A method of preparing the anode also is described. |
| FILED | Friday, February 14, 2020 |
| APPL NO | 16/791651 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/133 (20130101) H01M 4/134 (20130101) H01M 4/364 (20130101) H01M 4/386 (20130101) H01M 4/0404 (20130101) H01M 4/0471 (20130101) H01M 4/587 (20130101) H01M 4/622 (20130101) Original (OR) Class H01M 4/625 (20130101) H01M 4/1393 (20130101) H01M 4/1395 (20130101) H01M 10/0525 (20130101) H01M 50/20 (20210101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11411370 | Patra et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Susant Patra (Brentwood, California); Robert J. Deri (Pleasanton, California); John W. Elmer (Danville, California) |
| ABSTRACT | A Cu—Si—Cu substrate having a silicon substrate, copper plating on opposite sides of the silicon substrate, and copper vias extending thru the silicon substrate to electrically and thermally connect the copper platings together. The thicknesses of the silicon substrate and the copper platings are selected so that a coefficient of thermal expansion (CTE) of the Cu—Si—Cu substrate is substantially the same as a CTE of a material to be mounted on the Cu—Si—Cu substrate. |
| FILED | Thursday, March 24, 2016 |
| APPL NO | 15/080514 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/5226 (20130101) H01L 23/53228 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/021 (20130101) H01S 5/024 (20130101) H01S 5/0206 (20130101) H01S 5/02423 (20130101) H01S 5/02469 (20130101) Original (OR) Class H01S 5/4025 (20130101) H01S 5/32316 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11411724 | Grice et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Warren P. Grice (Oak Ridge, Tennessee); Bing Qi (Knoxville, Tennessee) |
| ABSTRACT | Continuous variable quantum secret sharing (CV-QSS) technologies are described that use laser sources and homodyne detectors. Here, a Gaussian-modulated coherent state (GMCS) prepared by one device passes through secure stations of other devices sequentially on its way to a trusted device, and each of the other devices coherently adds a locally prepared, independent GMCS to the group of propagating GMCSs. Finally, the trusted device measures both the amplitude and the phase quadratures of the received group of coherent GMCSs using double homodyne detectors. The trusted device suitably uses the measurement results to establish a secure key for encoding secret messages to be broadcast to the other devices. The devices cooperatively estimate, based on signals corresponding to their respective Gaussian modulations, the trusted device's secure key, so that the cooperative devices can decode the broadcast secret messages with the secure key. |
| FILED | Friday, July 31, 2020 |
| APPL NO | 16/944390 |
| ART UNIT | 2437 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0858 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11411983 | Dokucu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| INVENTOR(S) | Mustafa Tekin Dokucu (Latham, New York); Subhrajit Roychowdhury (Schenectady, New York); Olugbenga Anubi (Niskayuna, New York); Masoud Abbaszadeh (Clifton Park, New York); Justin Varkey John (Schenectady, New York) |
| ABSTRACT | An industrial asset may have monitoring nodes that generate current monitoring node values. An abnormality detection computer may determine that an abnormal monitoring node is currently being attacked or experiencing fault. A dynamic, resilient estimator constructs, using normal monitoring node values, a latent feature space (of lower dimensionality as compared to a temporal space) associated with latent features. The system also constructs, using normal monitoring node values, functions to project values into the latent feature space. Responsive to an indication that a node is currently being attacked or experiencing fault, the system may compute optimal values of the latent features to minimize a reconstruction error of the nodes not currently being attacked or experiencing a fault. The optimal values may then be projected back into the temporal space to provide estimated values and the current monitoring node values from the abnormal monitoring node are replaced with the estimated values. |
| FILED | Wednesday, October 16, 2019 |
| APPL NO | 16/654319 |
| ART UNIT | 2474 — Multiplex and VoIP |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 19/0092 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1441 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11406458 | Frederick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| INVENTOR(S) | Tom Frederick (Lincoln, Nebraska); Eric Markvicka (Brush, Colorado); Shane Farritor (Lincoln, Nebraska); Dmitry Oleynikov (Omaha, Nebraska) |
| ABSTRACT | The embodiments disclosed herein relate to various robotic and/or in vivo medical devices having compact joint configurations. Other embodiments relate to various medical device components, including forearms having grasper or cautery end effectors, that can be incorporated into certain robotic and/or in vivo medical devices. |
| FILED | Tuesday, August 13, 2019 |
| APPL NO | 16/538902 |
| ART UNIT | 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/14 (20130101) A61B 18/082 (20130101) A61B 18/1445 (20130101) A61B 34/30 (20160201) Original (OR) Class A61B 2017/00398 (20130101) A61B 2017/00407 (20130101) A61B 2017/00477 (20130101) A61B 2018/00595 (20130101) A61B 2018/1253 (20130101) A61B 2018/1422 (20130101) A61B 2034/305 (20160201) A61B 2217/005 (20130101) A61B 2217/007 (20130101) A61B 2218/002 (20130101) A61B 2218/007 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/046 (20130101) B25J 9/0087 (20130101) B25J 9/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406867 | Beck et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Christopher E. Beck (Houston, Texas); Eduardo Herrera (Houston, Texas); Austin Lovan (Houston, Texas); Jairo Sanchez (Houston, Texas); Andrew S. Donnan (Houston, Texas); Roger Rovekamp (Beavercreek, Ohio); Briana Luthman (Houston, Texas); Edward B. Behan (Shirley, New York); Richard M. Prince (Shirley, New York); Arthur J. Lekstutis (Shirley, New York) |
| ABSTRACT | A portable system for dynamometry, exercise, and rehabilitation comprises a base, a detachable servomotor assembly, an embedded control system, and a physical human-machine interface for securing a human limb into a stabilized position for use in a repeatable and ambidextrous manner. In another embodiment, the portable system includes a power source and a user interface subsystem for selecting operative modes and input parameters and for real-time processing, display, and storage of the values collected by the system during operation. In another embodiment, a method for determining strength of an isolated muscle group of a human joint is disclosed. The method includes the steps of mounting and securing a detachable servomotor assembly of a portable dynamometer upon a surface and securing the human joint to be tested into a stable position with an adjustable, ambidextrous distal limb attachment assembly for use of the portable dynamometer in a readily repeatable manner. |
| FILED | Thursday, October 24, 2019 |
| APPL NO | 16/663053 |
| ART UNIT | 3784 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/22 (20130101) A61B 5/224 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/02 (20130101) A61H 1/024 (20130101) A61H 1/0237 (20130101) A61H 2201/0149 (20130101) A61H 2201/163 (20130101) A61H 2201/0192 (20130101) A61H 2201/1215 (20130101) A61H 2201/1642 (20130101) A61H 2201/1671 (20130101) A61H 2201/5061 (20130101) Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 21/0058 (20130101) A63B 21/4047 (20151001) A63B 23/0494 (20130101) Original (OR) Class A63B 2208/0233 (20130101) A63B 2210/02 (20130101) A63B 2220/16 (20130101) A63B 2220/54 (20130101) A63B 2225/09 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11407792 | Silberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WILLIAM MARSH RICE UNIVERSITY (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Jonathan Silberg (Houston, Texas); Joshua T. Atkinson (Houston, Texas); Ian J. Campbell (Houston, Texas); George N. Bennett (Houston, Texas) |
| ABSTRACT | Engineered protein electron carriers, microorganisms expressing the same, and methods detecting regulated electron flow are described. |
| FILED | Friday, November 09, 2018 |
| APPL NO | 16/186226 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/21 (20130101) Original (OR) Class C07K 14/415 (20130101) C07K 2319/00 (20130101) C07K 2319/73 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/542 (20130101) G01N 33/566 (20130101) G01N 2333/79 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11408376 | Whitmore et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stephen Whitmore (Logan, Utah); Mark C. Heiner (Logan, Utah) |
| ASSIGNEE(S) | Utah State University (Logan, Utah) |
| INVENTOR(S) | Stephen Whitmore (Logan, Utah); Mark C. Heiner (Logan, Utah) |
| ABSTRACT | A hybrid rocket includes a housing having first and second ends, a solid-grain fuel material in the housing and defining a bore extending from end to end, two electrodes positioned adjacent to the fuel material to ignite the fuel material at the first end, a primary oxidizer port positioned at the first end to inject a primary oxidizer to flow in a downstream direction from the first end to the second end, a nozzle positioned at the second end and having a converging portion and a diverging portion, and a secondary oxidizer port to inject a secondary oxidizer downstream of the converging portion. The bore has a geometry configured to produce a hot-gas, fuel-rich mixture at the nozzle as the fuel material and primary oxidizer burn while flowing downstream. The diverging portion of the nozzle is configured to spontaneously combust the secondary oxidizer and the hot-gas, fuel-rich mixture. |
| FILED | Tuesday, August 11, 2020 |
| APPL NO | 16/990586 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Jet-propulsion Plants F02K 9/14 (20130101) F02K 9/26 (20130101) F02K 9/52 (20130101) F02K 9/72 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11408684 | Richard et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ADVANCED COOLING TECHNOLOGIES, INC. (Lancaster, Pennsylvania) |
| ASSIGNEE(S) | Advanced Cooling Technologies, Inc. (Lancaster, Pennsylvania) |
| INVENTOR(S) | Bradley Richard (Coatesville, Pennsylvania); William Anderson (Bound Brook, New Jersey); Richard W. Bonner, III (Lancaster, Pennsylvania); Devin Pellicone (Newtown, Pennsylvania); Chien-Hua Chen (Lititz, Pennsylvania); Greg Hoeschele (Lititz, Pennsylvania); Taylor Maxwell (Lancaster, Pennsylvania); Dan Pounds (Columbia, Missouri); Dan Reist (Mountville, Pennsylvania) |
| ABSTRACT | A loop heat pipe evaporator includes a porous primary wick, and a nonporous envelope unseparatingly surrounding the primary wick. The primary wick and the envelope are of one-piece construction. |
| FILED | Thursday, October 11, 2018 |
| APPL NO | 16/157841 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/046 (20130101) Original (OR) Class F28D 15/0266 (20130101) F28D 15/0283 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 11406322 | Lieber et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | REHABILITATION INSTITUTE OF CHICAGO (Chicago, Illinois) |
| ASSIGNEE(S) | REHABILITATION INSTITUTE OF CHICAGO (Chicago, Illinois) |
| INVENTOR(S) | Richard L. Lieber (Chicago, Illinois); Stojan Radic (San Diego, California); Kevin Young (San Diego, California) |
| ABSTRACT | Methods and systems for measuring muscle sarcomere length are disclosed. In an embodiment, a method comprises illuminating a set of muscle fibers with electromagnetic radiation, measuring an intensity of the electromagnetic radiation as reflected from the muscle fibers, the measuring occurring as a function of wavelength, determining wavelengths corresponding to maximums of reflected intensity, and correlating the determined wavelengths with respective muscle sarcomere lengths. In an embodiment, a system comprises an illumination source system for illuminating the set of muscle fibers with electromagnetic radiation, and an analyzer for measuring the intensity of the electromagnetic radiation as reflected from the muscle fibers. |
| FILED | Friday, September 27, 2019 |
| APPL NO | 16/585648 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0075 (20130101) A61B 5/0084 (20130101) A61B 5/1076 (20130101) A61B 5/1079 (20130101) A61B 5/4519 (20130101) Original (OR) Class A61B 2505/05 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11406646 | Ren et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Virginia Commonwealth University (Richmond, Virginia); Durect Corporation (Cupertino, California) |
| ASSIGNEE(S) | Virginia Commonwealth University (Richmond, Virginia); Durect Corporation (Cupertino, California); The United States Government as Represented by The Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Shunlin Ren (Richmond, Virginia); Leyuan Xu (Richmond, Virginia); Yanxia Ning (Richmond, Virginia); Jin Koung Kim (Richmond, Virginia); WeiQi Lin (Emerald Hills, California); Andrew R. Miksztal (Palo Alto, California); Hongwei Wu (Cupertino, California); Min L. Lee (Saratoga, California) |
| ABSTRACT | Compositions comprising 5-cholesten-3,25-diol, 3-sulfate (25HC3S) or pharmaceutically acceptable salt thereof and at least one cyclic oligosaccharide, e.g., a cyclodextrin (CD), are provided. The compositions may be used to prevent and/or treat a variety of diseases and conditions, including organ failure (e.g. acute liver failure), high cholesterol/high lipids, and various inflammatory diseases and conditions. |
| FILED | Tuesday, November 10, 2020 |
| APPL NO | 17/094432 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/63 (20130101) A61K 8/738 (20130101) A61K 9/0019 (20130101) A61K 9/19 (20130101) A61K 31/565 (20130101) Original (OR) Class A61K 31/575 (20130101) A61K 31/724 (20130101) A61K 47/10 (20130101) A61K 47/40 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/16 (20180101) A61P 3/06 (20180101) A61P 17/06 (20180101) A61P 31/04 (20180101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 19/00 (20130101) A61Q 19/004 (20130101) A61Q 19/007 (20130101) Steroids C07J 31/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11408844 | Suster et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio); UNIVERSITY OF PITTSBURGH (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERAN AFFAIRS (Washington, District of Columbia); UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Michael Suster (Cleveland Heights, Ohio); Pedram Mohseni (Highland Heights, Ohio); Anirban Sen Gupta (Cleveland, Ohio); Matthew David Neal (Sewickley, Pennsylvania); Ujjal Didar Singh Sekhon (Cleveland, Ohio); Sanjay Pitamber Ahuja (Cleveland Heights, Ohio); Sina Pourang (Cleveland Heights, Ohio); Debnath Maji (Ellsworth, Maine) |
| ABSTRACT | As one example, an apparatus includes a dielectric microsensor comprising a microfluidic chamber that includes a capacitive sensing structure, the microfluidic chamber including a fluid input port to receive a volume of a blood sample. A bioactive agent is disposed within the chamber to interact with the volume of the blood sample received in the microfluidic chamber. A transmitter provides an input radio frequency (RF) signal to an RF input of the dielectric microsensor. A receiver receives an output RF signal from an RF output of the dielectric microsensor. A computing device that computes dielectric permittivity values of the sample that vary over a time interval based on the output RF signal, the computing device to provide an assessment of hemostatic dysfunction and associated coagulopathy based on the dielectric permittivity values. |
| FILED | Wednesday, April 01, 2020 |
| APPL NO | 16/837704 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/026 (20130101) G01N 27/221 (20130101) Original (OR) Class G01N 27/226 (20130101) G01N 33/4905 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11406269 | Mulligan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Flashback Technologies, Inc. (Boulder, Colorado); The Regents of the University of Colorado (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Isobel Jane Mulligan (Niwot, Colorado); Gregory Zlatko Grudic (Niwot, Colorado); Steven L. Moulton (Littleton, Colorado) |
| ABSTRACT | Novel tools and techniques are provided for assessing, predicting and/or estimating a probability that a patient is bleeding, in some cases, noninvasively. In various embodiments, tools and techniques are provided for implementing rapid detection of bleeding of the patient or implementing assessment, prediction, or estimation of a probability of bleeding of the patient following injury, in some instances, in real-time before, during, and after fluid resuscitation. According to some embodiments, one or more sensors might monitor physiological data of the patient before, during, and after resuscitation following injury. A computer system might receive and analyze the physiological data, and might estimate a probability that the patient is bleeding, based at least in part on the analyzed physiological data. An indication of at least one of an assessment, prediction, or estimate of a probability that the patient is bleeding may then be displayed on a display device. |
| FILED | Monday, June 12, 2017 |
| APPL NO | 15/620701 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/002 (20130101) A61B 5/029 (20130101) A61B 5/031 (20130101) A61B 5/0075 (20130101) A61B 5/0205 (20130101) A61B 5/318 (20210101) A61B 5/369 (20210101) A61B 5/398 (20210101) A61B 5/742 (20130101) A61B 5/0809 (20130101) A61B 5/02028 (20130101) A61B 5/02042 (20130101) Original (OR) Class A61B 5/02152 (20130101) A61B 5/02241 (20130101) A61B 5/02416 (20130101) A61B 5/4836 (20130101) A61B 5/4848 (20130101) A61B 5/4875 (20130101) A61B 5/6826 (20130101) A61B 5/7246 (20130101) A61B 5/7267 (20130101) A61B 5/7275 (20130101) A61B 5/14532 (20130101) A61B 5/14546 (20130101) A61B 5/14551 (20130101) A61B 7/04 (20130101) A61B 8/488 (20130101) A61B 2562/0219 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/1613 (20140204) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/17 (20180101) G16H 40/63 (20180101) G16H 50/20 (20180101) G16H 50/30 (20180101) G16H 50/50 (20180101) G16H 50/70 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11410829 | Jing et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Euclid Beamlabs, LLC (Solon, Ohio) |
| ASSIGNEE(S) | Euclid Beamlabs, LLC (Solon, Ohio) |
| INVENTOR(S) | Chunguang Jing (Naperville, Illinois); Scott Ross (Cary, Illinois); Roman Kostin (Oak Park, Illinois); Yimei Zhu (East Setauket, New York) |
| ABSTRACT | A TEM sample holder enables simultaneous cooling and RF irradiation of a sample. The sample is suspended in a hole that penetrates through a sample stage formed by a dielectric plate having a lower metallic ground layer and an upper metallic lead. The sample stage is supported by an evacuated hollow tube extending from a cryogenic chamber, such as a liquid nitrogen or helium Dewar. A coaxial conductor extends from an ambient connector through the cryogenic chamber and hollow tube to the sample stage, a center conductor and surrounding metallic shield thereof being in thermal and electrical communication with the metallic lead and metallic ground layer respectively of the sample stage, and the metallic shield being is in direct thermal communication with the cryogenic chamber. The coaxial conductor thereby enables simultaneous cooling and RF irradiation of the sample during TEM measurements. Embodiments include a temperature sensor and heater. |
| FILED | Thursday, March 17, 2022 |
| APPL NO | 17/697034 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/20 (20130101) Original (OR) Class H01J 37/26 (20130101) H01J 2237/026 (20130101) H01J 2237/2001 (20130101) H01J 2237/24585 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11408008 | Marks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Michael David Marks (Roseville, Minnesota); Ratan Chopra (St. Paul, Minnesota) |
| ABSTRACT | This document provides oilseed plants (e.g., pennycress plants) having increased levels of one or more saturated fatty acids, increased levels of one or more polyunsaturated fatty acids (PUFAs), altered (e.g., increased or decreased) levels of oleic acid, and/or altered (e.g., increased or decreased) levels of erucic acid. For example, oilseed plants having reduced polypeptide levels and/or reduced polypeptide activity of one or more polypeptides involved in triglyceride synthesis (e.g., diacylglycerol O-acyltransferase 1 (TAG1) can have increased levels of stearic acid, increased levels of one or more PUFAs, altered levels of oleic acid, and/or altered levels of erucic acid. Also provided herein are methods and materials for making and using oilseed plants having increased levels of one or more saturated fatty acids, increased levels of one or more PUFAs, altered levels of oleic acid, and/or altered levels of erucic acid. |
| FILED | Thursday, March 26, 2020 |
| APPL NO | 16/831145 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 1/06 (20130101) A01H 5/10 (20130101) Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8247 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 11407528 | Washington, II et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | William J. Washington, II (North Potomac, Maryland); Christian Jordan (Baltimore, Maryland) |
| ABSTRACT | A bag unlocking method includes receiving, by a bag handling system, a bag during a check-in process. The bag handling system identifies, from a travel carrier system, traveler information corresponding to the bag. A securing device of the bag is programmed, using an unlock code pertaining to the traveler information. The bag handling system reads a bag tag of the bag at a baggage inspection station and determines the unlock code pertaining to the bag tag. The bag handling system transmits the unlock code to cause the securing device to unlock at the baggage inspection station. |
| FILED | Monday, September 20, 2021 |
| APPL NO | 17/479766 |
| ART UNIT | 2887 — Optics |
| CURRENT CPC | Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 1/366 (20130101) Original (OR) Class B64F 1/368 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
| US 11408850 | Xiao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yi Xiao (Miami, Florida); Juan Canoura (Hialeah Gardens, Florida) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida) |
| INVENTOR(S) | Yi Xiao (Miami, Florida); Juan Canoura (Hialeah Gardens, Florida) |
| ABSTRACT | The subject invention provides materials and methods for single-step fluorescence and electrochemical detection of small molecules, e.g., fentanyl and its analogs, in a sample. The subjection invention provides nucleic acids materials, e.g., aptamers (nucleic acid oligonucleotides) that can bind to fentanyl and its analogs with nanomolar affinity and high specificity against illicit drugs, adulterants, and cutting agents commonly existing in seized samples. The method for detecting fentanyl and/or its analogs in a sample comprises contacting the sample with an aptamer-based sensor selective for fentanyl and its analogs, and sensitively, specifically, and rapidly detecting fentanyl and/or its analogs in the sample. |
| FILED | Tuesday, June 22, 2021 |
| APPL NO | 17/354342 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) C12N 2310/16 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 27/3276 (20130101) Original (OR) Class G01N 27/3277 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 11411786 | Andrews |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Macdonald J. Andrews (Douglas, Massachusetts) |
| ABSTRACT | A method includes obtaining an in-phase (I) input signal and a quadrature (Q) input signal at a quadrature modulator. The method also includes performing constant envelope bi-phase shift keying (CE-BPSK) modulation using the quadrature modulator to generate a modulated output signal. The I and Q input signals comprise complementary transitions that alter a frequency of the modulated output signal while maintaining a substantially-constant amplitude of the modulated output signal. The transitions of the Q input signal are associated with data being encoded onto the modulated output signal, and the modulated output signal represents the data using two phases and has phase reversals positioned between the two phases. |
| FILED | Monday, May 03, 2021 |
| APPL NO | 17/306648 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 27/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 11406947 | Ruybal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Environmental Protection Agency (Denver, Colorado) |
| ASSIGNEE(S) | U.S. Environmental Protection Agency (Washington, District of Columbia) |
| INVENTOR(S) | Christopher Ruybal (La Jara, Colorado); Dominic DiGiulio (Ada, Oklahoma) |
| ABSTRACT | A rapid and continuous separator or equilibrator to separate a gas from a liquid includes a venturi and injector, a mixer and a free overfall stream to separate a gas from a liquid. The injector introduces a carrier medium into the liquid which provides a reservoir for the gas to diffuse into as the liquid and carrier make a single transit through the apparatus. The separator was developed to enable real-time estimation of methane concentrations in ground water during purging. Real-time monitoring allows evaluation of trends during water well purging, spatial trends between water wells, and temporal comparisons between sampling events. These trends may be a result of removal of stored casing water, pre-purge ambient borehole flow, formation physical and chemical heterogeneity, or vertical flow outside of well casing due to poor bentonite or cement seals. Real-time information in the field can help focus an investigation, aid in determining when to collect a sample, save money by limiting costs (e.g. analytical, sample transport and storage), and provide an immediate assessment of local methane concentrations, Four domestic water wells, one municipal water well, and one agricultural water well were sampled for traditional laboratory analysis and compared to the field separator or equilibrator results. Applying a paired t-test comparing the new separator or equilibrator method and traditional laboratory analysis yielded a p-value 0.383, suggesting no significant difference between the two methods for the current study. Additional field and laboratory-based experimentation and potential modification of this device are necessary to justify use beyond screening at this time. However, early separator or equilibrator use suggests promising results and applications. |
| FILED | Thursday, December 15, 2016 |
| APPL NO | 15/379905 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 23/23 (20220101) B01F 23/23762 (20220101) B01F 25/312 (20220101) Original (OR) Class Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 11410746 | Veneziano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Remi Veneziano (Allston, Massachusetts); Sakul Ratanalert (Cambridge, Massachusetts); Tyson Shepherd (Arlington, Massachusetts); Hyungmin Jun (Arlington, Massachusetts); Mark Bathe (Cambridge, Massachusetts) |
| ABSTRACT | Methods for the top-down design of nucleic acid nanostructures of arbitrary geometry based on target shape of spherical or non-spherical topology are described. The methods facilitate 3D molecular programming of lipids, proteins, sugars, and RNAs based on a DNA scaffold of arbitrary 2D or 3D shape. Geometric objects are rendered as node-edge networks of parallel nucleic acid duplexes, and a nucleic acid scaffold routed throughout the network using a spanning tree formula. Nucleic acid nanostructures produced according to top-down design methods are also described. In some embodiments, the nanostructures include single-stranded nucleic acid scaffold, DX crossovers, and staple strands. In other embodiments, the nanostructures include single-stranded nucleic acid scaffold, PX crossovers and no staples. Modified nanostructures include chemically modified nucleotides and conjugated to other molecules are described. |
| FILED | Thursday, April 27, 2017 |
| APPL NO | 16/097596 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/26 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/10 (20130101) C12N 15/11 (20130101) C12N 2320/32 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 15/00 (20190201) Original (OR) Class G16B 15/10 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 11406722 | Lux et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Regents of The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Caroline de Gracia Lux (Austin, Texas); Jacques Lux (Austin, Texas); Alexander M. Vezeridis (Austin, Texas); Robert F. Mattrey (Austin, Texas) |
| ABSTRACT | Stable perfluorocarbon nanodroplet compositions with properties such as low-boiling points and small particle diameters are provided for improved performance in ultrasound imaging and therapeutic applications. Methods of producing stabilized nanodroplet compositions and methods of using the compositions are further provided to allow for improved performance in ultrasound imaging techniques and/or therapeutic applications. |
| FILED | Friday, March 16, 2018 |
| APPL NO | 15/923845 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/225 (20130101) Original (OR) Class A61K 49/226 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 11408300 | Merry et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Brian Merry (Andover, Connecticut); Paul W. Duesler (Manchester, Connecticut) |
| ABSTRACT | A gas turbine engine may include a rotor overspeed protection (ROP) assembly. The ROP assembly may include an annular blade outer air seal (BOAS) assembly including a ROP segment. The ROP assembly may include a stator vane coupled with the BOAS assembly/. The stator vane may include a stator flange disposed about a forward edge portion of the stator vane. The ROP segment may include a ROP flange extending in an axially aft direction from a main body of the ROP segment toward the stator vane, wherein the ROP flange is disposed radially inward of the stator flange. |
| FILED | Monday, December 03, 2018 |
| APPL NO | 16/207669 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/08 (20130101) Original (OR) Class F01D 21/02 (20130101) F01D 21/04 (20130101) F01D 21/045 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/11 (20130101) F05D 2270/09 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11410844 | Spaun et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HONEYWELL INTERNATIONAL INC. (Charlotte, North Carolina) |
| ASSIGNEE(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| INVENTOR(S) | Benjamin Spaun (Westminster, Colorado); Zachary Price (Arvada, Colorado); Matthew Swallows (Lafayette, Colorado) |
| ABSTRACT | Devices, methods, and systems for enclosures for an ion trapping device are described herein. One enclosure for an ion trapping device includes a heat spreader base that includes a plurality of apertures. The ion trapping device may also include a grid array having a plurality of pins extending outward from a surface of the grid array. The apertures of the heat spreader base may be arranged such that the plurality of pins passes through the plurality of apertures. |
| FILED | Tuesday, November 17, 2020 |
| APPL NO | 16/950607 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/062 (20130101) H01J 49/4225 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, August 09, 2022.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20220809.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page