FedInvent™ Patents
Patent Details for Tuesday, August 30, 2022
This page was updated on Wednesday, August 31, 2022 at 05:37 AM GMT
Department of Health and Human Services (HHS)
| US 11426073 | Song et al. |
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| FUNDED BY |
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| APPLICANT(S) | Sheng-Kwei Song (St. Louis, Missouri); William M. Spees (St. Louis, Missouri); Tsen-Hsuan Lin (St. Louis, Missouri); Peng Sun (St. Louis, Missouri); Chunyu Song (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Sheng-Kwei Song (St. Louis, Missouri); William M. Spees (St. Louis, Missouri); Tsen-Hsuan Lin (St. Louis, Missouri); Peng Sun (St. Louis, Missouri); Chunyu Song (St. Louis, Missouri) |
| ABSTRACT | Repetitive electrical activity produces microstructural alteration in myelinated axons. These transient microstructural changes can be non-invasively visualized via two different magnetic-resonance-based approaches: diffusion fMRI and dynamic T2 spectroscopy in the ex vivo perfused bullfrog sciatic nerves. Non-invasive diffusion fMRI, based on standard diffusion tensor imaging (DTI), clearly localized the sites of axonal conduction blockage as might be encountered in neurotrauma or other lesion types. Diffusion fMRI response was graded in proportion to the total number of electrical impulses carried through a given locus. Diffusion basis spectrum imaging (DBSI) method revealed a reversible shift of tissue water into a restricted isotropic diffusion signal component, consistent with sub-myelinic vacuole formation. |
| FILED | Monday, April 29, 2019 |
| APPL NO | 16/398053 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) Original (OR) Class A61B 5/055 (20130101) A61B 5/742 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5608 (20130101) G01R 33/56341 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426129 | Fantini |
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| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
| ASSIGNEE(S) | Trustees of Tufts College (Medford, Massachusetts) |
| INVENTOR(S) | Sergio Fantini (Winchester, Massachusetts) |
| ABSTRACT | A method for inferring characteristics of a physiological system includes measuring one or more physiological signals in the physiological system and inferring characteristics of the physiological system from the one or more measured physiological signals using a multiple vascular compartment hemodynamic model, the multiple vascular compartment hemodynamic model defining a relationship between the one or more measured physiological signals and the characteristics of the physiological system. When the one or more measured physiological signals include coherent oscillations at a plurality of frequencies, the method is termed coherent hemodynamics spectroscopy. The multiple vascular compartment hemodynamic model is based on an average time spent by blood in one or more of said vascular compartments and a rate constant of oxygen diffusion. |
| FILED | Monday, October 21, 2013 |
| APPL NO | 14/654133 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0075 (20130101) A61B 5/0263 (20130101) A61B 5/02028 (20130101) A61B 5/4064 (20130101) A61B 5/7257 (20130101) A61B 5/7278 (20130101) Original (OR) Class A61B 5/14542 (20130101) A61B 5/14551 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426197 | Swaney et al. |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| INVENTOR(S) | Philip J. Swaney (Nashville, Tennessee); Robert J. Webster, III (Nashville, Tennessee) |
| ABSTRACT | A steerable surgical needle (10) includes an elongated needle shaft (12), a beveled tip portion (14), and a flexural element (16) that connects the needle shaft (12) with the tip portion (14) and permits the tip portion to deflect relative to the needle shaft. A method for steering the surgical needle (10) through tissue includes the steps of advancing the needle in the body tissue to induce tip flexure which causes the needle to follow a curved trajectory, and rotating the needle about its longitudinal axis in place, without advancement, to remove the tip flexure. |
| FILED | Wednesday, October 30, 2019 |
| APPL NO | 16/668291 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/3403 (20130101) Original (OR) Class A61B 17/3417 (20130101) A61B 2017/003 (20130101) A61B 2017/3454 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426308 | Keller |
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| APPLICANT(S) | Centricity Vision, Inc. (Fremont, California) |
| ASSIGNEE(S) | CENTRICITY VISION, INC. (Carlsbad, California) |
| INVENTOR(S) | Christopher Guild Keller (El Cerrito, California) |
| ABSTRACT | A surgical device and procedure are provided for smoothly and easily accessing tissue to perform microsurgery, including a capsulotomy of a lens capsule of an eye. The device includes a handpiece with a tip for insertion into an incision in the cornea of the eye. A sliding element is disposed within the handpiece and a suction cup is mounted to the sliding element. The sliding element can be translated to move the suction cup into and out of the handpiece. A compression mechanism associated with the suction cup and the handpiece compresses the suction cup for deployment through the tip of the handpiece. The suction cup can expand inside the anterior chamber into a cutting position on the lens capsule. A cutting element mounted to the suction cup is used to cut a portion of the lens capsule and to remove the portion from the eye. The cutting element may be mounted to a cutting element support structure in a way that prevents heating of the device. |
| FILED | Tuesday, June 30, 2020 |
| APPL NO | 16/917682 |
| ART UNIT | 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/14 (20130101) A61B 18/1402 (20130101) A61B 2018/00291 (20130101) A61B 2018/00321 (20130101) A61B 2018/00601 (20130101) A61B 2018/1407 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/0017 (20130101) A61F 9/00754 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426345 | Maisel et al. |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Katharina Maisel (Baltimore, Maryland); Laura Ensign (Baltimore, Maryland); Justin Hanes (Baltimore, Maryland); Richard Cone (Baltimore, Maryland) |
| ABSTRACT | Hypotonic formulations of hydrogel forming polymers, preferably poloxamers, have been developed for enhanced delivery through mucosa of therapeutic, diagnostic, prophylactic or other agents, to epithelial tissues, especially those having a mucosal coating. The polymers are administered at a concentration above, at or less than their critical gelling concentration (CRC) under isotonic conditions. The hypo tonicity of the formulation is adjusted so that the polymer gels at the lower concentration. A Poloxamer gel administered into the vagina or colorectal at its CRC will form a “plug” of gel in the lumen. |
| FILED | Thursday, November 14, 2019 |
| APPL NO | 16/684302 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/72 (20130101) A61K 8/90 (20130101) A61K 9/06 (20130101) A61K 9/08 (20130101) A61K 9/0012 (20130101) A61K 9/0031 (20130101) Original (OR) Class A61K 9/0034 (20130101) A61K 9/5146 (20130101) A61K 9/5153 (20130101) A61K 31/09 (20130101) A61K 31/09 (20130101) A61K 31/52 (20130101) A61K 31/352 (20130101) A61K 31/365 (20130101) A61K 31/365 (20130101) A61K 31/675 (20130101) A61K 47/10 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426368 | Lawrence et al. |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); EASTERN MICHIGAN UNIVERSITY (Ypsilanti, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); EASTERN MICHIGAN UNIVERSITY (Ypsilanti, Michigan) |
| INVENTOR(S) | Daniel A. Lawrence (Ann Arbor, Michigan); Cory Emal (Ann Arbor, Michigan); Ashley Reinke (Ann Arbor, Michigan); Shih-Hon Li (Ypsilanti, Michigan) |
| ABSTRACT | Provided herein are plasminogen activator-1 (PAI-1) inhibitor compounds and uses thereof in the treatment of any disease or disorder associated with elevated PAI-1. The disclosure includes, but is not limited to, the use of such compounds to prevent or reduce thrombosis and fibrosis, to promote thrombolysis, and to modulate lipid metabolism and treat diseases or disorders associated with elevated PAI-1, cholesterol, or lipid levels. |
| FILED | Friday, July 27, 2018 |
| APPL NO | 16/631066 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/137 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426371 | Loughran, Jr. et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia); UNIVERSITAT DE BARCELONA (Barcelona, Spain); Consejo Superior de Investigaciones Cientificas (CSIC) (Madrid, Spain) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia); Universität de Barcelona (Barcelona, Spain); Consejo Superior de Investigaciones Cientificas (CSIC) (Madrid, Spain) |
| INVENTOR(S) | Thomas P. Loughran, Jr. (Charlottesville, Virginia); Gemma Fabrias (Barcelona, Spain); Jose Luis Abad (Barcelona, Spain); Josefina Casas (Barcelona, Spain); David J. Feith (Palmyra, Virginia); Su-Fern Tan (Charlottesville, Virginia); Jennifer M. Pearson (Charlottesville, Virginia); Antonio Delgado Cirilo (Barcelona, Spain) |
| ABSTRACT | The present application provides novel compositions and methods for treating acute myeloid leukemia (AML). Compounds of the invention are acid ceramidase inhibitors, reduce AML cell viability, inhibit AML cell proliferation, increase cell death of AML cells, and induce apoptosis in AML cells. A primary compound of the invention is SACLAC: 2-chloro-N-((2S,3R)-1,3-dihydroxyoctadecan-2-yl)acetamide. The bromine analog of SACLAC (SABRAC: 2-bromo-N-((2S,3R)-1,3-dihydroxyoctadecan-2-yl)acetamide) is also useful for treating AML. SACLAC has much better activity than other know drugs used to treat AML. |
| FILED | Friday, April 27, 2018 |
| APPL NO | 16/609124 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/164 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426385 | Hammock et al. |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); United States as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); United States as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Bruce D. Hammock (Davis, California); Sung Hee Hwang (Woodland, California); Ralph W. de Vere White (Sacramento, California); Chong-xian Pan (Sacramento, California); Hongyong Zhang (Sacramento, California); Paul Henderson (Sacramento, California); Ai-Hong Ma (Sacramento, California); Maike Zimmermann (Sacramento, California); Fuli Wang (Xi'an, China PRC) |
| ABSTRACT | Provided are methods and compositions for prolonging survival and/or reducing or inhibiting tumor growth in a cancer subject receiving a regimen of one or more chemotherapeutic agents, an inhibitor of soluble epoxide hydrolase (sEHi) and a non-steroidal anti-inflammatory drug (NSAID) that inhibits one or more enzymes selected from the group consisting of cyclo-oxygenase (“COX”)-1, COX-2, and 5-lipoxygenase (“5-LOX”). The methods and compositions decrease toxicity and/or adverse side effects in subjects receiving a regimen of one or more chemotherapeutic agents. |
| FILED | Tuesday, August 14, 2018 |
| APPL NO | 16/641430 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/415 (20130101) Original (OR) Class A61K 31/7068 (20130101) A61K 33/243 (20190101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426389 | Racioppi |
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| APPLICANT(S) | Duke University (Durham, North Carolina); Luigi Racioppi (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Luigi Racioppi (Durham, North Carolina) |
| ABSTRACT | Described is a method for promoting regeneration of hematopoietic stem and progenitor cells in a subject in need thereof. The method comprises administering to the subject a composition comprising a Ca2+/calmodulin (CaM)-dependent protein kinase kinase 2 (CaMKK2) inhibitor. The CaMKK2 inhibitor may be a small molecule inhibitor, such as 7H-benzimidazo(2,1-a)benz(de)isoquinoline-7-one-3-carboxylic acid (STO-609). |
| FILED | Friday, July 27, 2018 |
| APPL NO | 16/634611 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426400 | Rubin et al. |
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| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Lee L. Rubin (Wellesly, Massachusetts); Amanda Gee (Alexandria, Virginia); Amy J. Wagers (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides methods for inducing, enhancing or increasing satellite cell proliferation, and an assay for screening for a candidate compound for inducing, enhancing or increasing satellite cell proliferation. Also provided are methods for repairing or regenerating a damaged muscle tissue of a subject. |
| FILED | Monday, May 25, 2020 |
| APPL NO | 16/882707 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/16 (20130101) A61K 31/47 (20130101) A61K 31/47 (20130101) A61K 31/58 (20130101) A61K 31/58 (20130101) A61K 31/136 (20130101) A61K 31/136 (20130101) A61K 31/165 (20130101) A61K 31/167 (20130101) A61K 31/404 (20130101) A61K 31/404 (20130101) A61K 31/485 (20130101) A61K 31/485 (20130101) A61K 31/496 (20130101) A61K 31/496 (20130101) A61K 31/553 (20130101) A61K 31/553 (20130101) A61K 31/4164 (20130101) A61K 31/4164 (20130101) A61K 31/4439 (20130101) A61K 31/4439 (20130101) A61K 31/4709 (20130101) Original (OR) Class A61K 31/7076 (20130101) A61K 31/7076 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/06 (20180101) Acyclic or Carbocyclic Compounds C07C 259/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426402 | Wiseman et al. |
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| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, Georgia) |
| INVENTOR(S) | R. Luke Wiseman (Chula Vista, California); Jeffery W. Kelly (La Jolla, California); Julia M. D. Grandjean (San Diego, California); Christina B. Cooley (San Antonio, Texas); Lars Plate (Nashville, Tennessee); Enrique Saez (San Diego, California); Aparajita Madhavan (San Diego, California); Bernard Kok (La Jolla, California) |
| ABSTRACT | Disclosed herein are compounds, their pharmaceutical salts, and pharmaceutical compositions that selectively activate the inositol-requiring enzyme 1 (IRE1)/X-box binding protein 1 (XBP1s) signaling pathway of the unfolded protein response (UPR), but that do not target the IRE1 kinase domain. The compounds are useful in treating diseases or conditions characterized by imbalances in proteostasis within the endoplasmic reticulum (ER) or secretory pathway, including those not associated with ER stress or activation of UPR. |
| FILED | Tuesday, May 26, 2020 |
| APPL NO | 15/929849 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/404 (20130101) A61K 31/415 (20130101) A61K 31/454 (20130101) A61K 31/497 (20130101) Original (OR) Class A61K 31/517 (20130101) A61K 31/522 (20130101) A61K 31/4439 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426405 | Sellar et al. |
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| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Rob Sellar (Newton, Massachusetts); Benjamin Ebert (Brookline, Massachusetts); Ofir Wolach (Boston, Massachusetts); Kimberly Martinod (Boston, Massachusetts); Denisa Wagner (Dover, Massachusetts) |
| ABSTRACT | The methods described herein include methods for the treatment of subjects who have Clonal Hematopoiesis of Indeterminate Potential (CHIP) or a Philadelphia-negative myeloproliferative neoplasm (MPN), e.g., polycythaemia vera (PV) or essential thrombocythaemia (ET), using inhibitors of JAK-STAT signaling. |
| FILED | Tuesday, December 04, 2018 |
| APPL NO | 16/209698 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) C12Q 1/6869 (20130101) C12Q 1/6876 (20130101) C12Q 1/6883 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426415 | Urano et al. |
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| APPLICANT(S) | Washington University (St. Louis, Missouri); The United States of America, As Represented by the Secretary, Department of Health and Human Services, Office of Technology Transfer, National Institutes of Health (Bethesda, Maryland) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri); The United States of America, As Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Fumihiko Urano (St. Louis, Missouri); Jana Mahadevan (Temecula, California); Amy Clark (St. Louis, Missouri); Ajit Jadhav (Chantilly, Virginia); David Maloney (Point of Rocks, Maryland); Brandon Harvey (Parkville, Maryland); Shyh-ming Yang (Doylestown, Pennsylvania); Mark Henderson (Damascus, Maryland) |
| ABSTRACT | The present invention generally relates to compositions and methods for treating or preventing an endoplasmic reticulum stress disorder in subjects, including compositions and methods for treating or preventing Wolfram syndrome. The present invention also relates to methods for treating symptoms of neurodegenerative diseases. |
| FILED | Tuesday, March 06, 2018 |
| APPL NO | 16/491826 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/155 (20130101) A61K 31/554 (20130101) Original (OR) Class A61K 31/4178 (20130101) A61K 31/4985 (20130101) A61K 45/06 (20130101) Peptides C07K 14/605 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426420 | Markowitz et al. |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio); Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio); BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Dallas, Texas) |
| INVENTOR(S) | Sanford Markowitz (Pepper Pike, Ohio); Won Jin Ho (Cleveland, Ohio); Yiyuan Yuan (Cleveland, Ohio); Mukesh Jain (Solon, Ohio); Mohamed Sabeh (Cleveland Heights, Ohio); Joseph Ready (Carrollton, Texas); Noelle Williams (Dallas, Texas) |
| ABSTRACT | A method of treating preventing, minimizing, and/or reversing congestive heart failure, cardiomyopathy, and/or reduction of cardiac ejection fraction in a subject in need thereof includes administering to the subject a therapeutically effective amount of a 15-PGDH inhibitor. |
| FILED | Monday, April 09, 2018 |
| APPL NO | 16/603544 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) A61K 31/496 (20130101) A61K 31/519 (20130101) A61K 31/704 (20130101) Original (OR) Class A61K 31/4355 (20130101) A61K 31/4365 (20130101) A61K 31/5377 (20130101) A61K 31/7048 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) Peptides C07K 16/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426422 | Yu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Research Development Foundation (Carson City, Nevada) |
| ASSIGNEE(S) | Research Development Foundation (Carson City, Nevada) |
| INVENTOR(S) | Hongtao Yu (Dallas, Texas); Eunhee Choi (Dallas, Texas) |
| ABSTRACT | Provided are methods for the treatment of insulin resistance and insulin receptor diseases with SHP2 inhibitors, such as allosteric inhibitors of SHP2 and RNAi or siRNA that target SHP2 expression. Compositions and methods for delivery of SHP2 inhibitors, such as liver-targeting liposomes or nanoparticles, are also provided. |
| FILED | Wednesday, January 30, 2019 |
| APPL NO | 16/261819 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/51 (20130101) A61K 9/0053 (20130101) A61K 9/127 (20130101) A61K 31/53 (20130101) A61K 31/497 (20130101) A61K 31/506 (20130101) A61K 31/7088 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 47/20 (20130101) A61K 47/26 (20130101) A61K 47/38 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) A61P 5/50 (20180101) A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) C12N 2310/313 (20130101) C12N 2310/322 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426423 | Pavel et al. |
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| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Ana Brandusa Pavel (New York, New York); Joshua David Campbell (Sharon, Massachusetts); Marc Elliott Lenburg (Brookline, Massachusetts); Avrum Elliot Spira (Newton, Massachusetts) |
| ABSTRACT | The methods and assays described herein relate to detection, diagnosis, and treatment of lung cancer, e.g., by detecting the level of expression of certain miRNAs described herein and/or by therapeutically increasing the level of those miRNAs. |
| FILED | Tuesday, March 24, 2020 |
| APPL NO | 16/828053 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) C12Q 1/6886 (20130101) C12Q 2539/10 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57423 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426448 | Podlasek et al. |
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| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois); THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois); BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY (Springfield, Illinois); THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois); THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois); BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY (Springfield, Illinois); THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Carol Podlasek (Chicago, Illinois); Samuel I. Stupp (Evanston, Illinois); Kevin McVary (Carbondale, Illinois); Dan Harrington (Houston, Texas) |
| ABSTRACT | Provided herein is technology relating to compositions comprising sonic hedgehog protein and therapeutic uses thereof. In particular, the technology relates to compositions comprising a hedgehog protein and one or more peptide amphiphiles for use in methods of treating or preventing stress urinary incontinence and/or erectile dysfunction in a subject. |
| FILED | Monday, May 13, 2019 |
| APPL NO | 16/410789 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/18 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 15/10 (20180101) Peptides C07K 14/47 (20130101) C07K 14/475 (20130101) C07K 14/4705 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426450 | Khademhosseini et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Alireza Khademhosseini (Cambridge, Massachusetts); Rahmi Oklu (Scottsdale, Arizona) |
| ABSTRACT | This disclosure relates to methods of using shear-thinning compositions in the treatment of a vascular disorders, cancers, infections, abscesses, and fistulas. |
| FILED | Monday, August 02, 2021 |
| APPL NO | 17/392088 |
| ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0019 (20130101) A61K 38/39 (20130101) Original (OR) Class A61K 47/02 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426460 | Deng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| INVENTOR(S) | Liang Deng (New York, New York); Stewart Shuman (New York, New York); Jedd D. Wolchok (New York, New York); Taha Merghoub (New York, New York); Peihong Dai (New York, New York); Weiyi Wang (New York, New York) |
| ABSTRACT | The present disclosure relates to infection-competent, but nonreplicative inactivated modified vaccinia Ankara (MVA) and its use as immunotherapy, alone, or in combination with immune checkpoint blocking agents for the treatment of malignant solid tumors. Particular embodiments relate to inducing an immune response in a subject diagnosed with a solid malignant tumor. |
| FILED | Friday, January 31, 2020 |
| APPL NO | 16/779174 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/12 (20130101) A61K 39/285 (20130101) Original (OR) Class A61K 39/39541 (20130101) A61K 39/39541 (20130101) A61K 39/39558 (20130101) A61K 39/39558 (20130101) A61K 45/06 (20130101) A61K 2039/54 (20130101) A61K 2039/505 (20130101) A61K 2039/585 (20130101) A61K 2039/5252 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/2818 (20130101) C07K 16/2827 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/24132 (20130101) C12N 2710/24134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426462 | Pages et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Diana Gil Pages (Rochester, Minnesota); Adam G. Schrum (Rochester, Minnesota) |
| ABSTRACT | This document provides methods and materials related to using monovalent anti-CD3 antibodies (e.g., monovalent anti-CD3 Fab fragments) as adjuvants to increase the immune response produced against an antigen (e.g., a tumor associated antigen). For example, vaccine compositions containing monovalent anti-CD3γε Fab fragments in combination with tumor associated antigens (e.g., tumor associated antigens having little or no immunogenicity in the absence of monovalent anti-CD3γε Fab fragments) alone or in combination with adjuvants for signals two and/or three required for full activation of T cell immune function, as well as methods and materials for using monovalent anti-CD3γε Fab fragments to increase the immune response produced against an antigen (e.g., a tumor associated antigen) within a mammal (e.g., a human) are provided. |
| FILED | Monday, April 02, 2018 |
| APPL NO | 15/943420 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 39/3955 (20130101) A61K 39/39558 (20130101) A61K 39/39558 (20130101) A61K 2039/505 (20130101) A61K 2039/5158 (20130101) A61K 2039/55516 (20130101) A61K 2039/55533 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/2809 (20130101) C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/35 (20130101) C07K 2317/55 (20130101) C07K 2317/75 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426464 | Georgiou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | George Georgiou (Austin, Texas); Everett Stone (Austin, Texas) |
| ABSTRACT | Methods and compositions related to the engineering of a protein with L-cyst(e)ine degrading enzyme activity are described. For example, in certain aspects there may be disclosed a modified cystathionine-γ-lyase comprising one or more amino acid substitutions and capable of degrading L-cyst(e)ine. Furthermore, certain aspects of the invention provide compositions and methods for the treatment of cancer with L-cyst(e)ine using the disclosed proteins or nucleic acids. |
| FILED | Wednesday, July 15, 2020 |
| APPL NO | 16/929438 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/51 (20130101) A61K 45/06 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) Enzymes C12Y 404/01001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426471 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia State University Research Foundation, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia State University Research Foundation, Inc. (Atlanta, Georgia) |
| INVENTOR(S) | Jenny Jie Yang (Atlanta, Georgia); Fan Pu (Atlanta, Georgia); Shenghui Xue (Atlanta, Georgia); Jingjuan Qiao (Atlanta, Georgia); Shanshan Tan (Atlanta, Georgia); Mani Salarian (Atlanta, Georgia) |
| ABSTRACT | Provided herein are protein contrast agents and targeted protein contrast agents, formulations thereof, and methods of use, including but not limited to, as a magnetic resonance imaging contrast agent. |
| FILED | Wednesday, September 09, 2020 |
| APPL NO | 17/015633 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/16 (20130101) A61K 49/126 (20130101) A61K 49/143 (20130101) Original (OR) Class Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 99/006 (20130101) Peptides C07K 14/76 (20130101) C07K 2319/32 (20130101) C07K 2319/33 (20130101) C07K 2319/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427542 | Thainashmuthu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Elex Biotech, Inc. (Portland, Oregon) |
| ASSIGNEE(S) | Elex Biotech, Inc. (Portland, Oregon) |
| INVENTOR(S) | Josephrajan Thainashmuthu (Fletcher, North Carolina); Martha Sibrian-Vazquez (Portland, Oregon); Douglas Boatman (Petaluma, California) |
| ABSTRACT | This disclosure concerns compounds and a method for modulating the activity of calcium ion channels, including Ca2+-induced (or Ca2+-activated) calcium release channels and conformationally coupled calcium release channels such as ryanodine receptors. Some of the compounds have a structure according to formula I, or a stereoisomer, tautomer, hydrate, solvate, prodrug, or pharmaceutically acceptable salt thereof. |
| FILED | Thursday, March 28, 2019 |
| APPL NO | 17/042616 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/04 (20180101) A61P 9/06 (20180101) Acyclic or Carbocyclic Compounds C07C 211/49 (20130101) C07C 217/88 (20130101) C07C 229/64 (20130101) C07C 309/24 (20130101) Heterocyclic Compounds C07D 209/44 (20130101) C07D 213/74 (20130101) Original (OR) Class C07D 215/12 (20130101) C07D 217/04 (20130101) C07D 231/56 (20130101) C07D 257/04 (20130101) C07D 271/06 (20130101) C07D 295/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427543 | Garkavtsev et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Igor Garkavtsev (Cambridge, Massachusetts); Rakesh K. Jain (Wellesley, Massachusetts) |
| ABSTRACT | This invention relates to antagonists of G3BP2, G3BP1, and ZEB1. Pharmaceutical compositions comprising G3BP2 inhibitors, methods of inhibiting G3BP2, G3BP1, and ZEB1, methods of treating cancer and inflammation, and methods of identifying an inhibitor of cancer stems cells are also provided. |
| FILED | Tuesday, July 18, 2017 |
| APPL NO | 16/318846 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 251/80 (20130101) Heterocyclic Compounds C07D 213/53 (20130101) C07D 213/82 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427552 | Beaton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | EPIGEN BIOSCIENCES, INC. (San Diego, California) |
| ASSIGNEE(S) | Epigen Biosciences, Inc. (San Diego, California) |
| INVENTOR(S) | Graham Beaton (San Diego, California); Fabio C. Tucci (San Diego, California); Satheesh B. Ravula (San Diego, California); Chandravadan R. Shah (San Diego, California); Hiep Luu (San Marcos, California) |
| ABSTRACT | Heterocyclic compounds are described that are lysophosphatidic acid receptor ligands that are useful in the treatment of lysophosphatidic acid receptor-dependent diseases and conditions, including but not limited to diseases involving fibrosis, such as fibrosis of the heart, kidney, liver and lung, and scleroderma; inflammatory diseases such as diabetic nephropathy and inflammatory bowel disease; ocular diseases such as diseases involving retinal degeneration; nerve diseases such as pruritus and pain. Non-limiting examples of those compounds include (RS)-3-Cyclopropyl-2-{4-[3-methyl-4-((R)-1-phenyl-ethoxycarbonylamino)-isoxazol-5-yl]-benzyloxy}-propionic acid and (R)-1-(4′-{5-[1-(2-Chloro-phenyl)-ethoxycarbonylamino]-4-fluoro-pyrazol-1-yl}-2-fluoro-biphenyl-4-yl)-cyclopropanecarboxylic acid. |
| FILED | Friday, February 07, 2020 |
| APPL NO | 16/784486 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/415 (20130101) Heterocyclic Compounds C07D 231/38 (20130101) C07D 231/52 (20130101) C07D 233/88 (20130101) C07D 239/42 (20130101) C07D 261/14 (20130101) Original (OR) Class C07D 263/48 (20130101) C07D 401/04 (20130101) C07D 413/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427569 | Tang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Weiping Tang (Middleton, Wisconsin); Gabrielle N. Winston-McPherson (Seattle, Washington); Haibo Xie (Madison, Wisconsin); Alan D. Attie (Madison, Wisconsin); Mark Patrick Keller (McFarland, Wisconsin); Ka Yang (Madison, Wisconsin) |
| ABSTRACT | Described are benzoimidazole indolyl methane compounds, pharmaceutical compositions containing them, and use of the compounds to inhibit PCSK9-mediated ailments. The compounds have the structure: |
| FILED | Thursday, February 13, 2020 |
| APPL NO | 16/789887 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/05 (20130101) Heterocyclic Compounds C07D 401/14 (20130101) C07D 403/06 (20130101) Original (OR) Class C07D 409/06 (20130101) C07D 413/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427582 | Cook et al. |
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| FUNDED BY |
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| APPLICANT(S) | UWM Research Foundation, Inc. (Milwaukee, Wisconsin) |
| ASSIGNEE(S) | UWM Research Foundation, Inc. (Milwaukee, Wisconsin) |
| INVENTOR(S) | James Cook (Milwaukee, Wisconsin); Daniel Knutson (Elkhorn, Wisconsin) |
| ABSTRACT | Provided herein are novel pyrazoloquinolinone compounds and method of using such compounds to treat disorders such as neuropsychiatric disorders with sensorimotor gating deficits, such as schizophrenia, tic disorders, attention deficit hyperactivity disorder, obsessive compulsive disorder, panic disorder, Huntington's disease and nocturnal enuresis; depression; temporomandibular myofascial pain; disorders of trigeminal nerve, such as trigeminal neuralgia and trigeminal neuropathy; migraine; and tinnitus. |
| FILED | Friday, October 23, 2020 |
| APPL NO | 17/078739 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4745 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/06 (20180101) A61P 25/18 (20180101) A61P 25/24 (20180101) A61P 27/16 (20180101) Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class C07D 471/14 (20130101) C07D 491/147 (20130101) C07D 495/14 (20130101) C07D 498/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427588 | Hertz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); MITOKININ, INC. (San Francisco, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); MITOKININ, INC. (San Francisco, California) |
| INVENTOR(S) | Nicholas T. Hertz (San Francisco, California); Kevan M. Shokat (San Francisco, California); Robert DeVita (Westfield, New Jersey) |
| ABSTRACT | Disclosed herein inter alia are compositions and methods useful in the treatment neurodegenerative diseases and cardiomyopathy, and for modulating the activity of PINK1. |
| FILED | Tuesday, May 26, 2020 |
| APPL NO | 16/883747 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 473/34 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427590 | Slusher et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland); Institute of Organic Chemistry and Biochemistry AS CR V.V.I. (Prague, Czech Republic) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland); Institute of Organic Chemistry and Biochemistry (Prague, Czech Republic) |
| INVENTOR(S) | Barbara Slusher (Kingsville, Maryland); Camilo Rojas (Baltimore, Maryland); Ajit G. Thomas (Baltimore, Maryland); Radim Nencka (Roztoky, Czech Republic); Michal Sala (Kladno, Czech Republic); Hubert Hrebabecky (Prague, Czech Republic); Norman Haughey (Baltimore, Maryland) |
| ABSTRACT | Small molecule inhibitors of neutral sphingomyelinase 2 (nSMase2) and their use for treating neurodegenerative diseases, such as, neurodegenerative diseases associated with high levels of ceramide, including, but not limited to Alzheimer's disease (AD), HIV-associated neurocognitive disorder (HAND), multiple sclerosis (MS), and amyotrophic lateral sclerosis (ALS), and, in other aspects, for treating cancer, are provided. |
| FILED | Friday, January 05, 2018 |
| APPL NO | 16/475433 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427595 | Porco, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts); SRI International (Menlo Park, California) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts); SRI INTERNATIONAL (Menlo Park, California) |
| INVENTOR(S) | John A. Porco, Jr. (Brookline, Massachusetts); Wenhan Zhang (Allston, Massachusetts); Tony Tianyi Wang (Centreville, Virginia); Shufeng Liu (Harrisonburg, Virginia) |
| ABSTRACT | Described herein are compounds, agents, compositions, and methods related to the treatment of a viral infection (e.g., Hepatitis C viral infection). In particular, the compounds, agents, compositions, and methods described herein inhibit viral entry into a target cell. |
| FILED | Tuesday, October 22, 2019 |
| APPL NO | 16/660285 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) Heterocyclic Compounds C07D 491/048 (20130101) Original (OR) Class C07D 491/147 (20130101) C07D 491/153 (20130101) C07D 498/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427612 | Stockdill et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wayne State University (Detroit, Michigan) |
| ASSIGNEE(S) | Wayne State University (Detroit, Michigan) |
| INVENTOR(S) | Jennifer L. Stockdill (West Bloomfield Township, Michigan); Christine A. Arbour (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure provides a method of solid-phase peptide synthesis from the N terminus to C terminus without detectable epimerization of the C-terminal amino acid. The method includes using derivatized amino acids comprising a diamino-aryl group. |
| FILED | Wednesday, August 21, 2019 |
| APPL NO | 16/546549 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 1/10 (20130101) C07K 1/023 (20130101) C07K 1/042 (20130101) Original (OR) Class C07K 1/084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427617 | Selsted et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Michael E. Selsted (Pasadena, California); Dat Q. Tran (Alhambra, California); Justin B. Schaal (Orange, California); Virginia Basso (North Hollywood, California) |
| ASSIGNEE(S) | THE UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| INVENTOR(S) | Michael E. Selsted (Pasadena, California); Dat Q. Tran (Alhambra, California); Justin B. Schaal (Orange, California); Virginia Basso (North Hollywood, California) |
| ABSTRACT | Novel peptide analogs of a θ-defensin have been developed that provide a biphasic effect in treating disseminated fungal disease and/or associated septic shock. These analogs are active at concentrations below those needed to provide a fungicidal effect, and function by initially mobilizing effector cells of the immune system to address the infective organism followed by regulation of the immune system to down regulate the inflammatory response. These novel θ-defensin analogs are protective at concentrations where naturally occurring θ-defensins have no apparent effect, and include a core set of structural and sequence features not found in native θ-defensins. |
| FILED | Friday, June 26, 2020 |
| APPL NO | 16/913699 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/00 (20180101) Peptides C07K 7/64 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427625 | Grandi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Paola Grandi (Cambridge, Massachusetts); Ndukaku Mgbechinyere Amankulor (Pittsburgh, Pennsylvania); Joseph C. Glorioso, III (Pittsburgh, Pennsylvania) |
| ABSTRACT | Provided is a recombinant viral vector that expresses a NKG2D activating ligand, such as a UL-16 binding protein. When introduced into a cancer cell, the vector can cause expression of the NKG2D activating ligand, thereby overcoming repression of NK-mediated (or other effector cell, e.g., macrophage) cytotoxicity and causing effector cell-mediated death of the cancer cell. Expression of the NKG2D activating ligand can be controlled by a miRNA present in greater concentration in noncancerous cells than in cancer cells, which can permit selective expression of the ligand in cancer cells and reduced cytotoxicity toward noncancerous cells. The vector can cause expression of an oncolytic factor. When formulated into a pharmaceutical composition and administered to a patient, the vector can be used to treat cancer. The cancer can be a glioma, such as glioblastoma including one with an isocitrate dehydrogenase (IDH) mutation. The vector can be a herpes simplex virus vector, among others. |
| FILED | Wednesday, June 14, 2017 |
| APPL NO | 16/309862 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/70539 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) C12N 2710/16632 (20130101) C12N 2710/16643 (20130101) C12N 2830/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427801 | Jenkins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio); UNIVERSITY HOSPITALS CLEVELAND MEDICAL CENTER (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio); UNIVERSITY HOSPITALS CLEVELAND MEDICAL CENTER (Cleveland, Ohio) |
| INVENTOR(S) | Michael W. Jenkins (Cleveland, Ohio); Yehe Liu (Cleveland, Ohio) |
| ABSTRACT | The present disclosure relates to a simple, fast, and low cost method for 3D microvascular imaging, termed “scatter labeled imaging of microvasculature in excised tissue” (SLIME). The method can include perfusing a contrast agent through vasculature of a tissue sample with a contrast perfusing unit (22). The contrast agent can include colloids and a dispersant. After the contrast agent is perfused through the vasculature, the vasculature of the tissue sample can be treated with a cross-linking agent delivery unit (24) providing a molecule that cross links with at least a portion of the dispersant to form a sticky, non-Newtonian polymer that prevents leakage of the contrast agent out of the vasculature of the tissue sample. The tissue sample can then be immersed in a solution comprising a clearing agent with an optical clearing unit (26) and subsequently imaged. |
| FILED | Friday, November 09, 2018 |
| APPL NO | 16/761278 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0018 (20130101) Original (OR) Class C12N 5/0679 (20130101) C12N 5/0691 (20130101) C12N 2513/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/49 (20130101) G01N 21/4795 (20130101) G01N 33/4833 (20130101) Image Data Processing or Generation, in General G06T 5/002 (20130101) G06T 5/009 (20130101) G06T 5/20 (20130101) G06T 5/50 (20130101) G06T 7/11 (20170101) G06T 7/0012 (20130101) G06T 7/136 (20170101) G06T 2207/10101 (20130101) G06T 2207/20224 (20130101) G06T 2207/30024 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427814 | Desai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Encodia, Inc. (San Diego, California) |
| ASSIGNEE(S) | ENCODIA, INC. (San Diego, California) |
| INVENTOR(S) | Kevin Desai (San Diego, California); Kevin L. Gunderson (San Diego, California); Robert C. James (San Diego, California); Lei Shi (San Diego, California); Stephen Verespy, III (San Diego, California) |
| ABSTRACT | Provided herein are modified cleavases for removing amino acids from peptides, polypeptides, and proteins. Also provided are methods of using the modified cleavases for treating polypeptides, and kits comprising the modified cleavase. In some embodiments, the methods and the kits also include other components for macromolecule sequencing and/or analysis. |
| FILED | Thursday, March 25, 2021 |
| APPL NO | 17/213169 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/485 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427816 | Awasthi |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Sanjay Awasthi (Lubbock, Texas) |
| ABSTRACT | Partial depletion of RLIP76 in p53 deficient living subject has shown many health benefits. In one embodiment, partical Rlip depletion is used to prevent or treat cancer in p53 deficient living subjects. In another embodiment, partial Rlip depletion is used for reversion of DNA-methylation abnormalities caused by the lack of p53 to normal in p53 deficient living subjects. In yet another embodiment, partial Rlip depletion is used in reduction of blood glucose, insulin-resistance, hyperlipidemina, or any combination thereof in p53 deficient living subjects. Methods of using liposome containing anti-sense nucleic acid or double stranded siRNA to partially deplete RLIP76 and thus treat p53 deficient subject are disclosed. The approaches described herein can be especially helpful in preventing cancer in Li-Fraumeni patients. |
| FILED | Wednesday, August 23, 2017 |
| APPL NO | 15/684508 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/40 (20130101) C07K 2317/34 (20130101) C07K 2317/73 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0693 (20130101) C12N 9/00 (20130101) C12N 11/18 (20130101) C12N 15/11 (20130101) C12N 15/113 (20130101) C12N 15/1024 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/315 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427817 | Josephs et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Eric Josephs (Durham, North Carolina); Dewran Kocak (Durham, North Carolina); Piotr Marszalek (Durham, North Carolina); Charles A. Gersbach (Durham, North Carolina) |
| ABSTRACT | Disclosed herein are optimized guide RNAs (gRNAs) that have increased target binding specificity and reduced off-target binding. Further disclosed herein are methods of designing and using the optimized gRNAs. |
| FILED | Thursday, August 25, 2016 |
| APPL NO | 15/754861 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) Original (OR) Class C12N 15/111 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 15/10 (20190201) G16B 15/30 (20190201) G16B 25/00 (20190201) G16B 30/10 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427819 | Stark et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CITY OF HOPE (Duarte, California) |
| ASSIGNEE(S) | CITY OF HOPE (Duarte, California) |
| INVENTOR(S) | Jeremy M. Stark (Duarte, California); Diana Yanez (Duarte, California) |
| ABSTRACT | A composition used in targeted mutagenesis is provided, which includes a first expression cassette comprising a nucleotide sequence which encodes a CAS9 endonuclease; a second expression cassette comprising a nucleotide sequence which encodes a guide RNA sequence, wherein the guide RNA sequence is complementary to a target genome nucleotide sequence in a cell; and a third expression cassette comprising a nucleotide sequence which encodes a Trex2 exonuclease (Trex2) gene. The first, second, and third expression cassettes may be a part or a portion of one or more expression vectors. |
| FILED | Wednesday, December 05, 2018 |
| APPL NO | 16/210337 |
| ART UNIT | 1699 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/96 (20130101) C12N 15/111 (20130101) Original (OR) Class C12N 2310/20 (20170501) Enzymes C12Y 301/00 (20130101) C12Y 301/11002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427852 | M'Koma |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Meharry Medical College (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Amosy M'Koma (Antioch, Tennessee) |
| ABSTRACT | Methods and materials are disclosed for testing biomarkers in a subject suffering from inflammatory bowel disease (IBD) are described herein. Such detection can be useful for diagnosing and treating ulcerative colitis (UC) and Crohn's disease (CD), two forms of IBD that are otherwise difficult to distinguish. The method includes measuring the level of one or more of several biomarkers, including HD5 or MMP-7, which are expressed differentially in patents with UC and CD. A treatment may be based on the determination of whether the subject has ulcerative colitis or Crohn's disease. |
| FILED | Friday, September 13, 2019 |
| APPL NO | 16/571034 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/37 (20130101) Original (OR) Class C12Q 1/6837 (20130101) C12Q 1/6876 (20130101) C12Q 1/6883 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/60 (20130101) G01N 33/68 (20130101) G01N 33/582 (20130101) G01N 2333/8146 (20130101) G01N 2800/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427856 | Seelig et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Georg Seelig (Seattle, Washington); Richard Muscat (London, United Kingdom); Alexander B. Rosenberg (Seattle, Washington) |
| ABSTRACT | Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens. |
| FILED | Monday, November 08, 2021 |
| APPL NO | 17/521263 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6855 (20130101) C12Q 1/6855 (20130101) C12Q 2563/179 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427857 | Chiu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| INVENTOR(S) | Daniel T. Chiu (Seattle, Washington); Jason E. Kreutz (Seattle, Washington); Gloria S. Yen (Seattle, Washington); Bryant S. Fujimoto (Seattle, Washington) |
| ABSTRACT | Methods, devices, and systems for performing digital assays are provided. In certain aspects, the methods, devices, and systems can be used for the amplification and detection of nucleic acids. In certain aspects, the methods, devices, and systems can be used for the recognition, detection, and sizing of droplets in a volume. Also provided are compositions and kits suitable for use with the methods and devices of the present disclosure. |
| FILED | Friday, March 06, 2020 |
| APPL NO | 16/812173 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) Original (OR) Class C12Q 1/6816 (20130101) C12Q 2531/113 (20130101) C12Q 2537/157 (20130101) C12Q 2563/107 (20130101) C12Q 2563/159 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1434 (20130101) G01N 21/47 (20130101) G01N 21/6428 (20130101) G01N 2015/1445 (20130101) G01N 2021/6439 (20130101) Image Data Processing or Generation, in General G06T 7/62 (20170101) G06T 2207/10056 (20130101) G06T 2207/30072 (20130101) Image or Video Recognition or Understanding G06V 10/507 (20220101) G06V 20/695 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427859 | Kanavarioti |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Anastassia Kanavarioti (El Dorado Hills, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anastassia Kanavarioti (El Dorado Hills, California) |
| ABSTRACT | Provided for herein is a method for detecting the presence of a nucleic acid target molecule in a biological sample. In certain aspects, the method comprises contacting a test sample that comprises (i) a biological sample comprising a nucleic acid target molecule and (ii) an osmylated single-stranded oligonucleotide probe comprising at least one pyrimidine residue covalently bonded to a substituted or unsubstituted Osmium tetroxide (OsO4)-2,2′-bypyridine group (OsBp group). |
| FILED | Friday, September 03, 2021 |
| APPL NO | 17/466931 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) C12Q 1/6832 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427865 | Ismagilov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Rustem F Ismagilov (Altadena, California); Jacob T Barlow (Pasadena, California); Said R. Bogatyrev (Pasadena, California) |
| ABSTRACT | Provided herein are methods and systems for absolute quantification of a target 16S rRNA and/or of a target prokaryotic taxon, based on amplifying and sequencing a same 16S rRNA recognition segment in which target 16S rRNA conserved regions flank 16S rRNA variable regions, conserved and variable among a plurality of sample 16S rRNAs and/or of a sample prokaryotic taxon of higher taxonomic rank with respect to the target taxon. In the methods and systems, absolute abundance of the a plurality of sample 16S rRNAs and/or of the sample prokaryotic taxon detected by the amplifying, is multiplied by the relative abundance of the target 16S rRNA and/or of a target prokaryotic taxon detected by the sequencing to provide the absolute quantification in accordance with method and systems of the disclosure. |
| FILED | Monday, July 13, 2020 |
| APPL NO | 16/927496 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class C12Q 1/6888 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427869 | Regev et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts); THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Aviv Regev (Cambridge, Massachusetts); Vijay K. Kuchroo (Boston, Massachusetts); Jellert Gaublomme (Cambridge, Massachusetts); Youjin Lee (Boston, Massachusetts); Chao Wang (Boston, Massachusetts); Nir Yosef (Oakland, California); Hongkun Park (Cambridge, Massachusetts); James Kaminski (Oakland, California) |
| ABSTRACT | This invention relates generally to compositions and methods for identifying the regulatory network that modulates, controls or otherwise influences T cell balance, for example, Th17 cell differentiation, maintenance and/or function, as well compositions and methods for exploiting the regulatory network that modulates, controls or otherwise influences T cell balance in a variety of therapeutic and/or diagnostic indications. This invention also relates generally to identifying and exploiting target genes and/or target gene products that modulate, control or otherwise influence T cell balance in a variety of therapeutic and/or diagnostic indications. |
| FILED | Friday, August 25, 2017 |
| APPL NO | 15/687089 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6881 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427876 | de Vlaminck et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Iwijn de Vlaminck (Stanford, California); Michael Kertesz (Menlo Park, California); Kiran Kaur Khush (Stanford, California); Mark Alec Kowarsky (Kowarsky, Australia); Lance Martin (Half Moon Bay, California); Stephen R. Quake (Stanford, California); Hannah Valantine (Stanford, California) |
| ABSTRACT | Methods, devices, compositions and kits are provided for analysis of the microbiome or individual components thereof in an individual. The methods find use in a determination of infection, in analysis of the microbiome structure, in determining the immunocompetence of an individual, and the like. In some embodiments of the invention, the individual is treated with an therapeutic regimen, e.g. drugs, diet, radiation therapy, and the like. |
| FILED | Monday, June 14, 2021 |
| APPL NO | 17/347247 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) C12Q 1/701 (20130101) C12Q 1/705 (20130101) Original (OR) Class C12Q 1/6883 (20130101) C12Q 1/6895 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) G16B 20/20 (20190201) G16B 30/00 (20190201) G16B 30/10 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427936 | Xie |
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| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska) |
| ASSIGNEE(S) | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska) |
| INVENTOR(S) | Jingwei Xie (Omaha, Nebraska) |
| ABSTRACT | Expanded, nanofiber structures are provided as well as methods of use thereof and methods of making. |
| FILED | Wednesday, September 19, 2018 |
| APPL NO | 16/647690 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 2791/005 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2073/00 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/003 (20130101) D01D 5/0007 (20130101) Original (OR) Class D01D 5/0015 (20130101) D01D 5/0023 (20130101) D01D 5/0038 (20130101) D01D 5/0046 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 6/625 (20130101) D01F 8/14 (20130101) Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding D04H 3/011 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 23/10 (20130101) D06M 2101/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11428626 | Ünlü et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | M. Selim Ünlü (Newton Highlands, Massachusetts); George Daaboul (Amesbury, Massachusetts); Abdulkadir Yurt (Brighton, Massachusetts) |
| ABSTRACT | An imaging system uses polarized light to illuminate the target and then uses a polarization filter to remove the light that is reflected from the target without modification. The target can include one or more anisotropic objects that scatter the light and alter the polarization state of the reflected light and causing it to be selectively transmitted to the imaging device which can record the transmitted light through the filter. The illuminating light can be circularly polarized and the filter can remove the circularly polarized light. The target can include asymmetric nanoparticles, such as nanorods that alter the amplitude or phase of the scattered light enabling pass through the filter to be detected by the imaging device. |
| FILED | Friday, October 18, 2019 |
| APPL NO | 16/657510 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02011 (20130101) G01B 2290/70 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/21 (20130101) Original (OR) Class G01N 21/45 (20130101) G01N 21/554 (20130101) G01N 2021/216 (20130101) G01N 2201/0683 (20130101) G01N 2201/06113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11428628 | Bhargava et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Rohit Bhargava (Urbana, Illinois); Kevin Lee Yeh (Corvallis, Oregon) |
| ABSTRACT | The disclosure is directed to methods and apparatus for obtaining a discrete frequency infrared (DFIR) spectroscopic image. The method includes generating, by a laser source, a pulsed laser beam comprising a spectral frequency in a mid-IR region and a pulse repetition rate; transmitting, by a first group of optical components, the pulsed laser beam onto a location of a sample; collecting, by a second group of optical components, an optical signal emitting from the location of the sample onto a detector to obtain a raw electric signal; demodulating, by a demodulator based on the pulse repetition rate, the raw electric signal to obtain an intensity value; and determining, by a control device and based on the intensity value, a pixel value corresponding to the spectral frequency in a DFIR spectroscopic image. |
| FILED | Monday, December 28, 2020 |
| APPL NO | 17/135010 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/02 (20130101) G01J 3/2823 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/35 (20130101) G01N 21/3563 (20130101) Original (OR) Class G01N 2201/0636 (20130101) G01N 2201/06113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
11428632 — Systems and methods for three-dimensional fluorescence polarization via multiview imaging
| US 11428632 | Shroff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| INVENTOR(S) | Hari Shroff (Bethesda, Maryland); Abhishek Kumar (Bethesda, Maryland); Shalin B. Mehta (Bethesda, Maryland); Patrick Jean-La Riviere (Bethesda, Maryland); Rudolf Oldenbourg (Bethesda, Maryland); Yicong Wu (Bethesda, Maryland); Talon Chandler (Bethesda, Maryland) |
| ABSTRACT | Systems and methods for three-dimensional fluorescence polarization excitation that generates maps of positions and orientation of fluorescent molecules in three or more dimensions are disclosed. |
| FILED | Thursday, May 31, 2018 |
| APPL NO | 16/616891 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6445 (20130101) Original (OR) Class G01N 21/6458 (20130101) Optical Elements, Systems, or Apparatus G02B 21/02 (20130101) G02B 21/16 (20130101) G02B 21/088 (20130101) G02B 21/367 (20130101) G02B 27/283 (20130101) G02B 27/286 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11428636 | Butte et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| ASSIGNEE(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| INVENTOR(S) | Pramod Butte (Los Angeles, California); Paul Lapchak (San Diego, California); David Scott Kittle (Running Springs, California) |
| ABSTRACT | The invention provides systems for characterizing a biological sample by analyzing emission of fluorescent light from the biological sample upon excitation and methods for using the same. The system includes a laser source, collection fibers, a demultiplexer and an optical delay device. All references cited herein are incorporated by reference in their entirety as though fully set forth. Unless defined otherwise, technical and scientific terms used herein have the same meaning as commonly understood by one of-ordinary skill in the art in which this invention belongs. |
| FILED | Thursday, March 11, 2021 |
| APPL NO | 17/198816 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0071 (20130101) A61B 5/0084 (20130101) A61B 5/1459 (20130101) A61B 5/4866 (20130101) A61B 5/14556 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/0218 (20130101) G01J 3/2889 (20130101) G01J 3/4406 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/64 (20130101) G01N 21/645 (20130101) G01N 21/6402 (20130101) G01N 21/6408 (20130101) G01N 21/6428 (20130101) G01N 21/6486 (20130101) Original (OR) Class G01N 2021/6417 (20130101) G01N 2021/6421 (20130101) G01N 2021/6484 (20130101) G01N 2201/06113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11428697 | Bapat et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SALK INSTITUTE FOR BIOLOGICAL STUDIES (La Jolla, California) |
| ASSIGNEE(S) | SALK INSTITUTE FOR BIOLOGICAL STUDIES (La Jolla, California) |
| INVENTOR(S) | Sagar P. Bapat (La Jolla, California); Ye Zheng (La Jolla, California); Ronald Evans (La Jolla, California); Michael Downes (La Jolla, California); Annette R. Atkins (La Jolla, California); Ruth T. Yu (La Jolla, California) |
| ABSTRACT | The invention features compositions and methods treating or preventing for age-related insulin resistance, type 2 diabetes and related disorders. The method involves depleting fTreg cells with an anti-ST2 antibody to decrease age-related fTreg accumulation and restore insulin sensitivity, thereby treating age-related insulin resistance, type 2 diabetes and related disorders. |
| FILED | Wednesday, December 04, 2019 |
| APPL NO | 16/702870 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/395 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) Peptides C07K 16/28 (20130101) C07K 16/2866 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6883 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) G01N 33/6869 (20130101) Original (OR) Class G01N 2333/7155 (20130101) G01N 2800/042 (20130101) G01N 2800/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11428768 | Sun |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Phillip Zhe Sun (Woburn, Massachusetts) |
| ABSTRACT | Methods and systems for producing a magnetic resonance (MR) image of a subject include acquiring a first physiological monitoring signal related to a first physiological process of the subject and acquiring a second physiological monitoring signal related to a second physiological process of the subject. The method also includes analyzing the first physiological monitoring signal and the second physiological monitoring signal to identify at least a first trigger point and a second trigger point and, upon identifying the first trigger point, applying a radiofrequency (RF) saturation module at a selected frequency to saturate a selected spin species in the subject. Upon identifying the second trigger point, the method includes performing a chemical exchange striation transfer (CEST) readout to acquire CEST data and then reconstructing the CEST data to produce a CEST image of the subject. |
| FILED | Thursday, April 05, 2018 |
| APPL NO | 15/946491 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/352 (20210101) A61B 5/0816 (20130101) A61B 5/7285 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4835 (20130101) G01R 33/5605 (20130101) Original (OR) Class G01R 33/5673 (20130101) G01R 33/56366 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11430279 | Beebe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | David J. Beebe (Monona, Wisconsin); Erwin Berthler (Madison, Wisconsin); Peter Cavnar (Madison, Wisconsin); David John Guckenberger (Oconomowoc, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | David J. Beebe (Monona, Wisconsin); Erwin Berthler (Madison, Wisconsin); Peter Cavnar (Madison, Wisconsin); David John Guckenberger (Oconomowoc, Wisconsin) |
| ABSTRACT | A microfluidic platform and method are provided. The microfluidic platform includes a base having an outer surface and a plurality of wells formed in the outer surface thereof for receiving fluid therein. The plurality of wells are in fluid communication with each other. A lid includes a plurality of channels having corresponding inputs and outputs. The lid is moveable between a first position wherein the lid is disengaged from the base and a second position wherein the inputs of each channel communicate with corresponding wells in the base. The fluid in each well is drawn into corresponding channels through the inputs thereof by capillary action. |
| FILED | Wednesday, May 09, 2012 |
| APPL NO | 13/467599 |
| ART UNIT | 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/0255 (20130101) B01L 3/0262 (20130101) B01L 3/0293 (20130101) B01L 3/563 (20130101) B01L 3/50273 (20130101) B01L 2200/16 (20130101) B01L 2300/047 (20130101) B01L 2300/0672 (20130101) B01L 2300/0816 (20130101) B01L 2400/024 (20130101) B01L 2400/0406 (20130101) B01L 2400/0481 (20130101) B01L 2400/0683 (20130101) Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere G07C 9/32 (20200101) Original (OR) Class G07C 9/38 (20200101) G07C 2209/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11426069 | Ettenhofer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| ASSIGNEE(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| INVENTOR(S) | Mark L. Ettenhofer (Silver Spring, Maryland); David Barry (Rockville, Maryland) |
| ABSTRACT | Provided are methods and system for assessing a human subject's neurological and/or psychological status. The methods entail displaying visual tests to a human subject, wherein each of the visual tests includes a visual target signal, optionally with visual cue signals, for eliciting visual and, optionally, body part, movements by the subject. Following the display, the movements are then detected. The latency and/or correctness of such movements can then be used to assess the subject's neurological and/or psychological status. Also provided are methods and systems for assessing performance validity. |
| FILED | Monday, March 10, 2014 |
| APPL NO | 14/773987 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/113 (20130101) Original (OR) Class A61B 5/162 (20130101) A61B 5/165 (20130101) A61B 5/168 (20130101) A61B 5/742 (20130101) A61B 5/1104 (20130101) A61B 5/4076 (20130101) A61B 5/4082 (20130101) A61B 5/4094 (20130101) A61B 5/4845 (20130101) A61B 5/4848 (20130101) A61B 5/4884 (20130101) A61B 5/7221 (20130101) A61B 5/7475 (20130101) A61B 2503/20 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426076 | Pierro |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vivonics, Inc. (Bedford, Massachusetts) |
| ASSIGNEE(S) | Vivonics, Inc. (Bedford, Massachusetts) |
| INVENTOR(S) | Michele Pierro (Westford, Massachusetts) |
| ABSTRACT | A contactless system for assessing and/or determining hemodynamic parameters and/or vital signs is featured. The system includes one or more contactless light sources configured to emit light incident on a moving living subject at one more wavelengths absorbed by one or more chromophores associated with spontaneous hemodynamic oscillations in a predetermined area of the living subject. The system includes a camera subsystem including one or more cameras configured to receive reflected light from the predetermined area of the moving living subject and configured to track motion of the predetermined area of the living subject within a field of view of the camera subsystem and configured to generate a time sequence of images of the predetermined area of the living subject. A controller is coupled the one or more light sources and the camera subsystem and is configured to acquire the time sequence of images and configured to generate one or more non-contact PPG waveforms and to assess and/or and determine one or hemodynamic parameters and/or vital signs from the one or more non-contact PPG waveforms. One or more polarizers are preferably each coupled to one of the one or more light sources are preferably configured to polarize the light to a polarized state such that the polarized light in the polarized state diffuses into the tissue in the predetermined area at a predetermined depth range and the polarized light is maintained in the polarized state at the predetermined depth range. A detector polarizer is preferably coupled to each of the one or more cameras and is configured to discriminate the light maintained in the polarized state and at the predetermined depth range and configured to generate the time sequence of images of the predetermined area with improved signal quality of the resulting non-contact PPG waveform. |
| FILED | Wednesday, November 25, 2020 |
| APPL NO | 17/104230 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/08 (20130101) A61B 5/0059 (20130101) A61B 5/0064 (20130101) A61B 5/0075 (20130101) Original (OR) Class A61B 5/0077 (20130101) A61B 5/1122 (20130101) A61B 5/02405 (20130101) A61B 5/6801 (20130101) A61B 5/6887 (20130101) A61B 5/14542 (20130101) A61B 2576/00 (20130101) Image Data Processing or Generation, in General G06T 2207/10016 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426080 | Stang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | John P. Stang (South Pasadena, California); Mark S. Haynes (Pasadena, California); Mahta Moghaddam (Los Angeles, California); Guanbo Chen (Los Angeles, California) |
| ABSTRACT | Methods and systems of monitoring and controlling thermal therapy treatments. One method includes determining, with an electronic processor, a propagation constant for a plurality of waveports. The method also includes modeling an object within an imaging cavity using a sparse mesh model. The method also includes determining a simulated impedance of the object based on the model of the object. The method also includes calibrating the simulated impedance with a theoretical impedance numerically calculated for the object. The method also includes determining a distribution of an electric field and a distribution of a magnetic field for a mode in a conformal modeled waveport based on the calibrated impedance and the model of the object. The method also includes exciting the plurality of waveports to generate the determined distribution of the electric field and the distribution of the magnetic field. |
| FILED | Monday, July 24, 2017 |
| APPL NO | 15/658305 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/015 (20130101) Original (OR) Class A61B 5/0036 (20180801) A61B 5/055 (20130101) A61B 5/4836 (20130101) A61B 8/463 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426389 | Racioppi |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina); Luigi Racioppi (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Luigi Racioppi (Durham, North Carolina) |
| ABSTRACT | Described is a method for promoting regeneration of hematopoietic stem and progenitor cells in a subject in need thereof. The method comprises administering to the subject a composition comprising a Ca2+/calmodulin (CaM)-dependent protein kinase kinase 2 (CaMKK2) inhibitor. The CaMKK2 inhibitor may be a small molecule inhibitor, such as 7H-benzimidazo(2,1-a)benz(de)isoquinoline-7-one-3-carboxylic acid (STO-609). |
| FILED | Friday, July 27, 2018 |
| APPL NO | 16/634611 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426450 | Khademhosseini et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Alireza Khademhosseini (Cambridge, Massachusetts); Rahmi Oklu (Scottsdale, Arizona) |
| ABSTRACT | This disclosure relates to methods of using shear-thinning compositions in the treatment of a vascular disorders, cancers, infections, abscesses, and fistulas. |
| FILED | Monday, August 02, 2021 |
| APPL NO | 17/392088 |
| ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0019 (20130101) A61K 38/39 (20130101) Original (OR) Class A61K 47/02 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426476 | Brown et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as Represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Michael Hunter Brown (La Jolla, California); Nicholas Ray Caruso (San Diego, California) |
| ABSTRACT | An internal ultraviolet-C light emitting diode antifouling system and method that include a waterproof, light transmissible potted enclosure; an object disposed within the waterproof, light transmissible potted enclosure; and at least one ultraviolet-C light emitting diode disposed within the waterproof, light transmissible enclosure, wherein the at least one ultraviolet-C light emitting diode is configured to emit light on the object, wherein the light is configured to prevent biofouling on the object. |
| FILED | Thursday, December 12, 2019 |
| APPL NO | 16/712588 |
| ART UNIT | 1799 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/10 (20130101) Original (OR) Class Cleaning in General; Prevention of Fouling in General B08B 17/02 (20130101) Ships or Other Waterborne Vessels; Equipment for Shipping B63B 59/04 (20130101) B63B 59/08 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/325 (20130101) C02F 2201/3222 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426610 | Puleo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Niskayuna, New York) |
| INVENTOR(S) | Christopher Michael Puleo (Niskayuna, New York); Victoria Eugenia Cotero (Troy, New York); Jeffrey Michael Ashe (Gloversville, New York); John Frederick Graf (Ballston Lake, New York) |
| ABSTRACT | Embodiments of the present disclosure relate to techniques for inducing physiological perturbations in a subject via neuromodulation, e.g., peripheral neuromodulation of a region of interest of an organ. The nature and degree of the perturbations may be related to the subject's clinical condition. Accordingly, an assessment of one or more characteristics of the perturbations may be used to determine a clinical condition of the subject. |
| FILED | Tuesday, April 30, 2019 |
| APPL NO | 16/399692 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0536 (20130101) A61N 1/36017 (20130101) A61N 7/00 (20130101) Original (OR) Class A61N 2007/0026 (20130101) A61N 2007/0073 (20130101) A61N 2007/0078 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426729 | Yoon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Euisik Yoon (Ann Arbor, Michigan); Yu-Heng Cheng (Ann Arbor, Michigan); Yu-Chih Chen (Ann Arbor, Michigan); Riley Brien (Ann Arbor, Michigan); Max S. Wicha (Ann Arbor, Michigan) |
| ABSTRACT | The present disclosure relates to systems and methods for whole cell analysis. In particular, the present disclosure relates to single cell genomic analysis (e.g., gene expression analysis. |
| FILED | Friday, January 19, 2018 |
| APPL NO | 16/480396 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502738 (20130101) Original (OR) Class B01L 3/502761 (20130101) B01L 2200/0668 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2300/0883 (20130101) B01L 2300/0893 (20130101) B01L 2400/086 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427345 | Hinson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Kimberly A. Hinson (Seattle, Washington); Jung Soon Jang (Bellevue, Washington); Blain A. Lawson (Tukwila, Washington); Christopher M. Jacobus (Saint Louis, Missouri) |
| ABSTRACT | Described are systems and methods for deploying and stowing a refueling boom. In certain examples, deploying the refueling boom includes lowering a refueling boom structure with a hoist while a boom aerodynamic control surface of the refueling is deactivated, determining that first transition conditions have been met, switching the hoist actuator state mode, and activating the boom aerodynamic control surface. In other examples, stowing the refueling boom includes flying the refueling boom towards a fuselage, determining that second transition conditions have been met, switching the hoist actuator state mode, and raising a refueling boom structure of the refueling boom with the hoist. |
| FILED | Tuesday, March 31, 2020 |
| APPL NO | 16/835962 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 39/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427352 | Estevo, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | Curtis Raymond Estevo, Jr. (Mesa, Arizona); Jared Cook Tompkinson (Mesa, Arizona); Talmadge Eugene Ryan, III (Gilbert, Arizona); Carlos R. Aguirre (Apache Junction, Arizona); James Curtis Eason (San Tan Valley, Arizona); Erich Lloyd Zimmerman (Mesa, Arizona) |
| ABSTRACT | A rotorcraft service fixture includes a fixture body and one or more rotor assembly connectors rigidly attached to or integral with the fixture body. The one or more rotor assembly connectors are sized and shaped to provide an interference fit with a portion of a rotor assembly of a rotorcraft to removably attach the fixture body to the portion of the rotor assembly. The rotorcraft service fixture also includes one or more support connectors rigidly attached to or integral with the fixture body. The one or more support connectors are sized and shaped to provide an interference fit with a partially detached component of the rotor assembly to immobilize the partially detached component during inspection or maintenance of the rotor assembly. |
| FILED | Friday, February 08, 2019 |
| APPL NO | 16/271633 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 5/10 (20170101) B64F 5/40 (20170101) Original (OR) Class B64F 5/60 (20170101) Technical Subjects Covered by Former US Classification Y10T 29/37 (20150115) Y10T 29/49318 (20150115) Y10T 29/53983 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427543 | Garkavtsev et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Igor Garkavtsev (Cambridge, Massachusetts); Rakesh K. Jain (Wellesley, Massachusetts) |
| ABSTRACT | This invention relates to antagonists of G3BP2, G3BP1, and ZEB1. Pharmaceutical compositions comprising G3BP2 inhibitors, methods of inhibiting G3BP2, G3BP1, and ZEB1, methods of treating cancer and inflammation, and methods of identifying an inhibitor of cancer stems cells are also provided. |
| FILED | Tuesday, July 18, 2017 |
| APPL NO | 16/318846 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 251/80 (20130101) Heterocyclic Compounds C07D 213/53 (20130101) C07D 213/82 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427815 | Van Damme et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | KONINKLIJKE PHILIPS N.V. (Eindhoven, Netherlands) |
| ASSIGNEE(S) | Koninklijke Philips N.V. (Eindhoven, Netherlands) |
| INVENTOR(S) | Hendrik Sibolt Van Damme ('s-Hertogenbosch, Netherlands); Wilbert Hendrik Bouwman (Elst, Netherlands) |
| ABSTRACT | A simplified method of obtaining purified nucleic acids uses a single buffer solution to both wash and elute nucleic acids bound to a binding phase. Use of a single buffer solution avoids the time-consuming aspect of using different wash and elution buffer solutions during multiple nucleic acid purification steps. The method for purifying nucleic acids using a single buffer solution includes steps of: exposing a sample comprising nucleic acids to a nucleic acid binding phase, where the nucleic acid binding phase may include magnetic particles, silica particles, or a mixture thereof; and allowing the nucleic acids to bind to the nucleic acid binding phase; washing the nucleic acids bound to the nucleic acid binding phase at least once with the single buffer solution at room temperature; and eluting the nucleic acids from the nucleic acid binding phase with ≤50 μl of the single buffer solution, at a temperature of ≥40° Celsius. |
| FILED | Tuesday, December 27, 2016 |
| APPL NO | 16/065843 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1006 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427865 | Ismagilov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Rustem F Ismagilov (Altadena, California); Jacob T Barlow (Pasadena, California); Said R. Bogatyrev (Pasadena, California) |
| ABSTRACT | Provided herein are methods and systems for absolute quantification of a target 16S rRNA and/or of a target prokaryotic taxon, based on amplifying and sequencing a same 16S rRNA recognition segment in which target 16S rRNA conserved regions flank 16S rRNA variable regions, conserved and variable among a plurality of sample 16S rRNAs and/or of a sample prokaryotic taxon of higher taxonomic rank with respect to the target taxon. In the methods and systems, absolute abundance of the a plurality of sample 16S rRNAs and/or of the sample prokaryotic taxon detected by the amplifying, is multiplied by the relative abundance of the target 16S rRNA and/or of a target prokaryotic taxon detected by the sequencing to provide the absolute quantification in accordance with method and systems of the disclosure. |
| FILED | Monday, July 13, 2020 |
| APPL NO | 16/927496 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class C12Q 1/6888 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11428348 | Di Carlo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Tony Di Carlo (Long Beach, California); Brian T. Vaniman (Fountain Valley, California); John P. Leuer (Newport Beach, California) |
| ABSTRACT | A method of fabricating a conduit comprises steps of attaching a first first-tubular-outboard-ply-end of a first tubular outboard ply to a first inner collar portion of a first collar with a second weld and attaching a second first-tubular-outboard-ply end of the first tubular outboard ply to a second inner collar portion of a second collar with a fourth weld. The method also comprises steps of inserting a second tubular outboard ply into the first tubular outboard ply and inserting a tubular inboard ply into the second tubular outboard ply, so that the second tubular outboard ply is interposed between the tubular inboard ply and the first tubular outboard ply. The method further comprises steps of threadably interconnecting the first inner collar portion and a first outer collar portion of the first collar and threadably interconnecting the second inner collar portion and a second outer collar portion of the second collar. |
| FILED | Thursday, January 14, 2021 |
| APPL NO | 17/149543 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 11/22 (20130101) F16L 11/121 (20130101) Original (OR) Class F16L 11/122 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 3/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11428368 | Rauscher et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornerstone Research Group, Inc. (Miamisburg, Ohio) |
| ASSIGNEE(S) | Cornerstone Research Group, Inc. (Miamisburg, Ohio) |
| INVENTOR(S) | Michael D. Rauscher (Dayton, Ohio); Thomas J. Barnell (Dayton, Ohio); Gary N. Cupp (Waynesville, Ohio); Michael J. Fisher (Springboro, Ohio); Ryan D. Snyder (Kettering, Ohio) |
| ABSTRACT | A method of making a fiber reinforced energetic composite is provided. The method includes providing a mold or mandrel defining a shape for the fiber reinforced energetic composite, providing an impregnated fiber layup over the mold or mandrel, and curing the impregnated fiber layup. The impregnated fiber layup includes a fiber layup and polymer resin, the fiber layup formed from a plurality of reinforcing fiber layers and an energetic polymer nanocomposite disposed adjacent one or more of the reinforcing fiber layers with the polymer resin impregnated within the reinforcing fiber layers. The energetic polymer nanocomposite includes core-shell nanoparticles entrained in a thermoplastic polymer matrix where the core-shell nanoparticles include a core made of metal and at least one shell layer made of metal oxide disposed on the core or a core made of metal oxide and at least one shell layer made of metal disposed on the core. |
| FILED | Monday, April 20, 2020 |
| APPL NO | 16/853079 |
| ART UNIT | 1782 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 70/30 (20130101) B29C 70/68 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2105/162 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/712 (20130101) Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 1/04 (20130101) Original (OR) Class F17C 2203/0607 (20130101) F17C 2203/0636 (20130101) F17C 2203/0663 (20130101) F17C 2270/0197 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11428475 | Rush et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| INVENTOR(S) | Brian Magann Rush (Niskayuna, New York); Daniel Jason Erno (Clifton Park, New York); Thomas Adcock (Glenville, New York); Stefano Angelo Mario Lassini (Lowell, Michigan) |
| ABSTRACT | A cooling assembly includes walls extending around and defining an enclosed vapor chamber that holds a working fluid. An interior porous wick structure is disposed inside the chamber and lines interior surfaces of the walls. The wick structure includes pores that hold a liquid phase of the working fluid. The cooling assembly also includes an exterior porous wick structure lining exterior surfaces of the walls outside of the vapor chamber. The exterior wick structure includes pores that hold a liquid phase of a cooling fluid outside the vapor chamber. The interior wick structure holds the liquid working fluid until heat from an external heat source vaporizes the working fluid inside the vapor chamber. The exterior wick structure holds the liquid fluid outside the vapor chamber until heat from inside the vapor chamber vaporizes the liquid cooling fluid in the exterior wick structure for transferring heat away from the heat source. |
| FILED | Wednesday, July 08, 2020 |
| APPL NO | 16/923080 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/342 (20151001) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Cosmonautics; Vehicles or Equipment Therefor B64G 1/506 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/046 (20130101) Original (OR) Class F28D 2021/0021 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/427 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11428485 | Engel, IV et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Textron Systems Corporation (Hunt Valley, Maryland) |
| ASSIGNEE(S) | Textron Systems Corporation (Hunt Valley, Maryland) |
| INVENTOR(S) | William Henry Engel, IV (Cockeysville, Maryland); David Timothy Horst (Bel Air, Maryland) |
| ABSTRACT | A firearm for firing case-telescoped (CT) rounds includes a barrel configured for transit of a bullet of a live CT cartridge in a live-fire operating mode. The live CT cartridge is chambered and fired from a live-fire chamber installed in the live-fire operating mode. The firearm further includes a blank-fire chamber configured to chamber and fire a blank CT cartridge in a blank-fire operating mode, wherein the blank-fire chamber has a second diameter less than a first diameter of the live-fire chamber, to prevent chambering of the live CT cartridge in the blank-fire operating mode. The arrangement can enhance safety by preventing accidental firing of a live round during operation when it is assumed that only blanks are being fired. |
| FILED | Friday, January 15, 2021 |
| APPL NO | 17/150218 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 11/02 (20130101) Original (OR) Class F41A 21/26 (20130101) F41A 21/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11428487 | Shipley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Textron Systems Corporation (Hunt Valley, Maryland) |
| ASSIGNEE(S) | Textron Systems Corporation (Hunt Valley, Maryland) |
| INVENTOR(S) | Paul Andrew Shipley (Millers, Maryland); Cameron Mehdi Brand (Towson, Maryland); Kevin Michael Ayotte (Baltimore, Maryland); Joshua Stephen Ruck (Baltimore, Maryland); Benjamin Tyler Cole (Baltimore, Maryland); William Henry Engel, IV (Cockeysville, Maryland) |
| ABSTRACT | A firearm for firing cased telescoped (CT) ammunition cartridges that includes a split chamber configured to fully support a CT cartridge when it is fired, and that includes i) a dynamic rear chamber portion defining a pocket in a face of a bolt, and ii) a static front chamber portion that is integral to the barrel and separate from the bolt. A cartridge extraction mechanism engages the CT cartridge prior to the CT cartridge being fired, and holds the CT cartridge in the pocket in the bolt face as the bolt moves rearward to pull the CT cartridge out of the static front chamber portion and into an ejection position. An ejector is operable to eject the CT cartridge from the pocket in the face of the bolt when the CT cartridge reaches the ejection position. |
| FILED | Tuesday, April 13, 2021 |
| APPL NO | 17/229261 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 3/26 (20130101) F41A 15/14 (20130101) Original (OR) Class Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 5/045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11428681 | Swager et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Timothy M. Swager (Newton, Massachusetts); Sophie Liu (Cambridge, Massachusetts); Graham Sazama (Chestnut Hill, Massachusetts); Alexander R. Petty (Allston, Massachusetts); Jan M. Schnorr (Boston, Massachusetts) |
| ABSTRACT | A sensor can include a conductive region in electrical communication with at least two electrodes, the conductive region including a conductive material and an alkene-interacting metal complex. |
| FILED | Monday, November 04, 2019 |
| APPL NO | 16/673893 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/127 (20130101) G01N 33/0047 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 436/21 (20150115) Y10T 436/216 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11428802 | Barngrover et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Christopher Michael Barngrover (San Diego, California); Amin Mohammad Rahimi (San Diego, California); Jacoby Ryan Larson (Surprise, Arizona); Julian Yousif Raheema (El Cajon, California) |
| ABSTRACT | A system for localization includes a radar, a database, a simulator, a registrar, and a filter. The radar is positioned at a disposed location requiring localization. The radar generates a radar image scanning a proximity around the disposed location. The database stores features of a landmass. The simulator generates synthesized images of the features that the radar is predicted to generate from corresponding viewpoints. The registrar calculates respective correlation indicators between the radar image and each synthesized image. The filter sets a pose estimate of the disposed location to an average of those viewpoints from which correspond the synthesized images having the best or better ones of the correlation indicators. |
| FILED | Tuesday, June 16, 2020 |
| APPL NO | 16/902581 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/04 (20130101) G01S 13/86 (20130101) G01S 13/9021 (20190501) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11428820 | Barr et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LOCKHEED MARTIN CORPORATION (Bethesda, Maryland) |
| ASSIGNEE(S) | LOCKHEED MARTIN CORPORATION (Bethesda, Maryland) |
| INVENTOR(S) | Keith Stabler Barr (Erie, Colorado); Philip Gatt (Berthoud, Colorado); Derek Andrew Hutton (Golden, Colorado) |
| ABSTRACT | A system for determining airborne light detection and ranging (lidar) installation angles includes an airborne platform, a light detection and ranging (lidar) apparatus, a navigation system and a processor. The airborne platform performs a calibration flight in an orbit. The lidar apparatus is installed on the airborne platform for wind-velocity measurement. The navigation system is on board the airborne platform and measures motion data associated with movements of the airborne platform and generates a navigation signal. The processor determines in real time one or more installation angles of the lidar apparatus on the airborne platform to improve accuracy of the wind-velocity measurement. |
| FILED | Monday, September 16, 2019 |
| APPL NO | 16/572500 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/58 (20130101) G01S 17/89 (20130101) G01S 17/95 (20130101) Original (OR) Class G01S 19/42 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0094 (20130101) G05D 1/0202 (20130101) Electric Digital Data Processing G06F 1/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11428832 | Drukier et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | IMAGE INSIGHT INC. (East Hartford, Connecticut) |
| ASSIGNEE(S) | IMAGE INSIGHT, INC. (East Hartford, Connecticut) |
| INVENTOR(S) | Gordon A. Drukier (New Haven, Connecticut); Eric P. Rubenstein (Longmeadow, Massachusetts); Yonatan B. Rubenstein (Longmeadow, Massachusetts); Joshua C. Kessler (East Longmeadow, Massachusetts); Peter R. Solomon (West Hartford, Connecticut); Marek A. Wojtowicz (East Hartford, Connecticut) |
| ABSTRACT | Systems and methods for calibrating multiple electronic devices are described herein. Such methods may include obtaining, by a processor, data from a plurality of reference electronic devices, analyzing, by a processor, the data and calibrating, by the processor, the electronic device based on the analyzed data obtained from the plurality of reference electronic devices. |
| FILED | Tuesday, November 12, 2013 |
| APPL NO | 14/078129 |
| ART UNIT | 2862 — Printing/Measuring and Testing |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/02 (20130101) G01T 7/005 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/20 (20130101) G06T 7/80 (20170101) G06T 7/85 (20170101) Pictorial Communication, e.g Television H04N 7/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11428929 | Arbabi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SAMSUNG ELECTRONICS CO., LTD. (Suwon-si, South Korea); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | SAMSUNG ELECTRONICS CO., LTD. (Suwon-si, South Korea); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Amir Arbabi (Pasadena, California); Seunghoon Han (Seoul, South Korea); Andrei Faraon (Pasadena, California) |
| ABSTRACT | A focusing device includes a substrate and a plurality of scatterers provided at both sides of the substrate. The scatterers on the both sides of the focusing device may correct geometric aberration, and thus, a field of view (FOV) of the focusing device may be widened. |
| FILED | Thursday, May 28, 2020 |
| APPL NO | 16/885729 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 3/0087 (20130101) G02B 5/0263 (20130101) G02B 5/0294 (20130101) G02B 5/1876 (20130101) G02B 5/3083 (20130101) G02B 23/00 (20130101) G02B 27/005 (20130101) G02B 27/0031 (20130101) Original (OR) Class G02B 27/0927 (20130101) G02B 27/0955 (20130101) G02B 27/4216 (20130101) G02B 27/4272 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11429021 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Haitao Liu (Pittsburgh, Pennsylvania); Cheng Tian (Shanghai, China PRC); Hyo Jeong Kim (Pittsburgh, Pennsylvania) |
| ABSTRACT | A method of forming a patterned device includes depositing at least one nanostructure comprising self-assembled nucleic acids formed into a predetermined conformation upon a surface of a substrate, depositing a stabilizing layer of material mechanically stronger than the at least one nanostructure over the at least one nanostructure and the surface of the substrate to form a positive pattern template, depositing a layer of a first polymer over the positive pattern template, and removing the layer of the first polymer from connection with the positive pattern template, wherein the layer of the first polymer includes a surface having a negative imprint of the positive pattern template. |
| FILED | Wednesday, May 30, 2018 |
| APPL NO | 15/993579 |
| ART UNIT | 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/60 (20130101) B05D 5/00 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 33/3842 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/00 (20130101) B32B 11/02 (20130101) B32B 13/00 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11429105 | Sorin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina); BROWN UNIVERSITY (Providence, Rhode Island) |
| INVENTOR(S) | Daniel J. Sorin (Durham, North Carolina); George D. Konidaris (Durham, North Carolina); William Floyd-Jones (Durham, North Carolina); Sean Murray (Durham, North Carolina) |
| ABSTRACT | A system for motion planning for autonomous vehicles can include a plurality of sensors, a plurality of detectors in electrical communication with the plurality of sensors, and a motion planning module in electrical communication with the plurality of detectors and a computing system of an autonomous vehicle. The motion planning module stores a planning graph with each node representing, explicitly or implicitly, time and variables defining a state of the autonomous vehicle, an operating environment, or both the state of the autonomous vehicle and the operating environment. A reconfigurable processor can include a collision detection module and, optionally, a shortest path module. Pre-computed collision data and planning graph data reflecting logical/physical node mapping can be communicated to the processor during a programming phase and used during runtime. |
| FILED | Friday, June 09, 2017 |
| APPL NO | 16/308693 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/20 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0088 (20130101) G05D 1/0214 (20130101) Original (OR) Class G05D 1/0217 (20130101) G05D 1/0274 (20130101) G05D 2201/0213 (20130101) Electric Digital Data Processing G06F 16/9024 (20190101) Traffic Control Systems G08G 1/165 (20130101) G08G 1/166 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11429273 | Curtis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Jess Willard Curtis (Shalimar, Florida); Emily Doucette (Fort Walton Beach, Florida) |
| ABSTRACT | A touch-based tracking method comprises starting a GUI which displays an environment; observing at least one of the presence or absence of one or more targets in relation to features in the environment; when an observation is made, reporting the observation through the GUI to form an input; reporting the observation in the GUI with a hand gesture; applying an algorithm to convert the input into a probability distribution; and updating a target state estimate and alters the environment display. The environment may be an area or a map, and the map may include a plurality of features, e.g. roads, building structures, forest, and water. The observation indicates the presence or non-presence of the one or more targets. The hand gesture is made on the map, such as a swiping motion with one or more fingers on the GUI, wherein the hand gesture indicates the strength of the observation. |
| FILED | Tuesday, May 22, 2018 |
| APPL NO | 15/985752 |
| ART UNIT | 2178 — Graphical User Interface and Document Processing |
| CURRENT CPC | Electric Digital Data Processing G06F 3/04847 (20130101) G06F 3/04883 (20130101) Original (OR) Class G06F 2203/04808 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11429480 | Hornung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | Bryan Hornung (Plano, Texas); David Patrick (McKinney, Texas) |
| ABSTRACT | Systems, apparatuses, and methods related to chiplets are described. A chiplet-based system may include a memory controller chiplet to control accesses to a storage array, and the memory controller chiplet can facilitate error correction and cache management in a manner to minimize interruptions to a sequence of data reads to write corrected data from a prior read back into the storage array. For example, a read command may be received at a memory controller device of the memory system from a requesting device. Data responsive to the read command may be obtained and determined to include a correctable error. The data may be corrected, transmitted to the requesting device and written to cache of the memory controller device with an indication that data is valid and dirty (e.g., includes an error or corrected error). The data is written back to the memory array in response to a cache eviction event. |
| FILED | Monday, August 31, 2020 |
| APPL NO | 17/007811 |
| ART UNIT | 2112 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 11/106 (20130101) G06F 11/1068 (20130101) Original (OR) Class G06F 11/3037 (20130101) G06F 12/0246 (20130101) G06F 12/0891 (20130101) G06F 13/1668 (20130101) G06F 2212/7209 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11429812 | Nataraj et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mayachitra, Inc. (Santa Barbara, California) |
| ASSIGNEE(S) | Mayachitra, Inc. (Santa Barbara, California) |
| INVENTOR(S) | Lakshmanan Nataraj (Goleta, California); Tajuddin Manhar Mohammed (Goleta, California); Tejaswi Nanjundaswamy (Goleta, California); Michael Gene Goebel (Santa Barbara, California); Bangalore S. Manjunath (Santa Barbara, California); Shivkumar Chandrasekaran (Santa Barbara, California) |
| ABSTRACT | Systems, devices, methods and instructions are described for detecting GAN generated images. On embodiment involves receiving an images, generating co-occurrence matrices on color channels of the image, generating analysis of the image by using a convolutional neural network trained to analyze image features of the images based on the generated co-occurrence matrices and determining whether the image is a GAN generated image based on the analysis. |
| FILED | Wednesday, February 26, 2020 |
| APPL NO | 16/801866 |
| ART UNIT | 2631 — Digital Communications |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6257 (20130101) Original (OR) Class G06K 9/6262 (20130101) Computer Systems Based on Specific Computational Models G06N 3/088 (20130101) G06N 3/0454 (20130101) Image or Video Recognition or Understanding G06V 10/56 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11429862 | Chai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | SRI INTERNATIONAL (Menlo Park, California) |
| INVENTOR(S) | Sek Meng Chai (Princeton, New Jersey); Aswin Nadamuni Raghavan (Princeton, New Jersey); Samyak Parajuli (East Brunswick, New Jersey) |
| ABSTRACT | Techniques are disclosed for training a deep neural network (DNN) for reduced computational resource requirements. A computing system includes a memory for storing a set of weights of the DNN. The DNN includes a plurality of layers. For each layer of the plurality of layers, the set of weights includes weights of the layer and a set of bit precision values includes a bit precision value of the layer. The weights of the layer are represented in the memory using values having bit precisions equal to the bit precision value of the layer. The weights of the layer are associated with inputs to neurons of the layer. Additionally, the computing system includes processing circuitry for executing a machine learning system configured to train the DNN. Training the DNN comprises optimizing the set of weights and the set of bit precision values. |
| FILED | Monday, September 17, 2018 |
| APPL NO | 16/133446 |
| ART UNIT | 2123 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/10 (20130101) G06N 3/084 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11429887 | Ferguson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | David George Ferguson (Takoma Park, Maryland); Cheong Yiu Li (Batavia, Illinois); Jens Koch (Evanston, Illinois); Moe Shwan Khalil (Baltimore, Maryland) |
| ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia); NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | David George Ferguson (Takoma Park, Maryland); Cheong Yiu Li (Batavia, Illinois); Jens Koch (Evanston, Illinois); Moe Shwan Khalil (Baltimore, Maryland) |
| ABSTRACT | One example includes a tunable current-mirror qubit. The qubit includes a plurality of flux tunable elements disposed in a circuit loop. A first portion of the flux tunable elements can be configured to receive a first input flux and a remaining portion of the flux tunable elements can be configured to receive a second input flux to control a mode of the tunable current-mirror qubit between a microwave excitation mode to facilitate excitation or quantum state manipulation of the tunable current-mirror qubit via a microwave input signal and a noise-protected mode to facilitate storage of the quantum state of the tunable current-mirror qubit. The qubit also includes at least one capacitor interconnecting nodes between respective pairs of the flux tunable elements to facilitate formation of Cooper-pair excitons in each of the microwave excitation mode and the noise-protected mode. |
| FILED | Friday, March 01, 2019 |
| APPL NO | 16/290324 |
| ART UNIT | 2849 — AI & Simulation/Modeling |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/0354 (20130101) G01R 33/0358 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/223 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11430171 | Amer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | SRI INTERNATIONAL (Menlo Park, California) |
| INVENTOR(S) | Mohamed R. Amer (Brooklyn, New York); Timothy J. Meo (Kendall Park, New Jersey); Xiao Lin (Princeton, New Jersey) |
| ABSTRACT | This disclosure describes techniques that include generating, based on a description of a scene, a movie or animation that represents at least one possible version of a story corresponding to the description of the scene. This disclosure also describes techniques for training a machine learning model to generate predefined data structures from textual information, visual information, and/or other information about a story, an event, a scene, or a sequence of events or scenes within a story. This disclosure also describes techniques for using GANs to generate, from input, an animation of motion (e.g., an animation or a video clip). This disclosure also describes techniques for implementing an explainable artificial intelligence system that may provide end users with information (e.g., through a user interface) that enables an understanding of at least some of the decisions made by the AI system. |
| FILED | Friday, December 21, 2018 |
| APPL NO | 16/231059 |
| ART UNIT | 2167 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/345 (20190101) G06F 16/738 (20190101) G06F 16/9024 (20190101) G06F 40/205 (20200101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6215 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/084 (20130101) G06N 3/088 (20130101) G06N 3/0445 (20130101) G06N 3/0454 (20130101) G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 7/251 (20170101) G06T 13/40 (20130101) G06T 13/80 (20130101) Original (OR) Class G06T 2207/10016 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30196 (20130101) Image or Video Recognition or Understanding G06V 20/41 (20220101) G06V 20/46 (20220101) G06V 40/20 (20220101) G06V 40/23 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11430644 | Schmitt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Spark Thermionics, Inc. (Berkeley, California) |
| ASSIGNEE(S) | Spark Thermionics, Inc. (Berkeley, California) |
| INVENTOR(S) | Felix Schmitt (Berkeley, California); Jared William Schwede (Berkeley, California); Adam Lorimer (Berkeley, California) |
| ABSTRACT | A system for thermionic energy generation, preferably including one or more thermionic energy converters, and optionally including one or more power inputs, airflow modules, and/or electrical loads. A thermionic energy converter, preferably including an emitter module, a collector module, and/or a seal, and optionally including a spacer. The thermionic energy converter preferably defines a chamber and/or a heating cavity. A method for thermionic energy generation, preferably including receiving power, emitting electrons, and/or receiving the emitted electrons, and optionally including convectively transferring heat. |
| FILED | Tuesday, May 26, 2020 |
| APPL NO | 16/883762 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 45/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11430711 | Lin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Aegis Technology Inc. (Santa Ana, California) |
| ASSIGNEE(S) | Aegis Technology Inc. (Santa Ana, California) |
| INVENTOR(S) | Zhigang Lin (Santa Ana, California); Chunhu Tan (Santa Ana, California); Shuyi Chen (Santa Ana, California) |
| ABSTRACT | A high performance, lead free, Ag paste thermal interface material (TIM) for die attachment and substrate bonding in electronic packaging includes: (i) multiscale silver particles, (ii) metal-coated carbon nanotubes (CNTs), (iii) a polymer, and (iv) a liquid carrier. The multiscale silver particles and metal-coated carbon nanotubes, which function as hybrid filler components, are uniformly dispersed within the TIM composition. The sintered TIM exhibits high density, high mechanical strength, and high thermal conductivity. The components of the liquid carrier including the solvent, binder, surfactants, and thinner are completely evaporated or burned off during sintering. Sintering of the TIM can be conducted at a relatively low temperature, without or with very low (<0.1 MPa) pressure, in open air and without vacuum or inert gas protection. The TIM can be utilized in substrate bonding not only on conventional metal-plated surfaces but also bare Cu substrate surfaces. |
| FILED | Tuesday, November 26, 2019 |
| APPL NO | 16/696105 |
| ART UNIT | 2894 — Semiconductors/Memory |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 30/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/158 (20170801) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 5/00 (20130101) C01G 19/00 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/61 (20130101) C01P 2004/62 (20130101) C01P 2004/64 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/4882 (20130101) H01L 23/3737 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11430939 | Miesner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | John E. Miesner (Fairfax, Virginia); George G. Zipfel, Jr. (Summit, New Jersey) |
| ABSTRACT | Exemplary practice of the present invention provides a magnetostrictive actuator characterized by linear force output and uniform magnetic biasing. A center bias magnet drives flux through series magnetostrictive bars in opposite directions while surrounding drive coils apply flux in the same direction through the bars. The net response is substantially linear with respect to the drive coil current. A second parallel set of magnetostrictive bars completes the flux path and adds to the actuator output force. Flux leakage between the parallel bars is compensated by a ferromagnetic shunt or by a tapered magnet providing uniform flux density down the length of the magnetostrictive bars. The closed flux path allows magnetic shielding of the entire actuator, if desired. |
| FILED | Friday, March 19, 2021 |
| APPL NO | 17/206929 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/06 (20130101) H01L 41/12 (20130101) Original (OR) Class H01L 41/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11430984 | Freeman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Adam W. Freeman (Laurel, Maryland); Konstantinos Gerasopoulos (Odenton, Maryland); Spencer A. Langevin (Odenton, Maryland) |
| ABSTRACT | Electrodes including a passivation layer formed prior to receiving an initial charge are provided. The electrodes comprise an electrode-composition including an active electrode species, in which the electrode-composition comprises a first surface. The electrodes also comprise a passivation layer positioned onto at least a portion of the first surface. The passivation layer comprises: (i) a matrix material comprising (a) a cured propoxylated polymer, (b) an uncured hydrophobic glycol ether, or a combination of (a) and (b); and (ii) at least a first electrolyte. The electrodes may be included into an electrochemical cell. |
| FILED | Saturday, August 31, 2019 |
| APPL NO | 16/558044 |
| ART UNIT | 1759 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/366 (20130101) Original (OR) Class H01M 4/0407 (20130101) H01M 4/623 (20130101) H01M 10/0525 (20130101) H01M 10/0565 (20130101) H01M 10/0568 (20130101) H01M 10/0569 (20130101) H01M 2004/021 (20130101) H01M 2300/0014 (20130101) H01M 2300/0082 (20130101) H01M 2300/0085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11431040 | Tomar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Vikas Tomar (West Lafayette, Indiana); Bing Li (West Lafayette, Indiana); Vilas G. Pol (West Lafayette, Indiana); Ryan Andrew Adams (Redwood City, California); Mihit Hitendra Parekh (West Lafayette, Indiana) |
| ABSTRACT | A battery having a thermal protection arrangement is disclosed which includes a housing, a first electrode, a second electrode, a polymer porous separator positioned between the first electrode and the second electrode, an electrolyte interspersed between the first electrode, the second electrode, and the polymer porous separator, at least one sensor holder having an electrode side and a housing side, with at least one cavity provided on the electrode side, the at least one sensor holder in firm contact with the first electrode or the second electrode, and at least one temperature sensor placed in the at least one cavity of the at least one sensor holder, the at least one cavity sized such that the outer surface of the temperature sensor being flush with remaining surface of the at least one sensor holder, and wherein the at least one temperature sensor has no contact with the polymer porous separator. |
| FILED | Friday, August 30, 2019 |
| APPL NO | 16/557954 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/382 (20130101) H01M 4/525 (20130101) H01M 4/662 (20130101) H01M 10/486 (20130101) Original (OR) Class H01M 50/411 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11431144 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| ASSIGNEE(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| INVENTOR(S) | Jianfeng Wu (Tucson, Arizona); Karl D. Nelson (Plymouth, Minnesota); Matthew Wade Puckett (Phoenix, Arizona) |
| ABSTRACT | An optical resonator device, which can be implemented in a Brillouin laser, comprises a first waveguide ring resonator having a first diameter, and one or more second waveguide ring resonators adjacent to the first waveguide ring resonator. The one or more second waveguide ring resonators each have a second diameter that is less than the first diameter. The one or more second waveguide ring resonators optically communicate with the first waveguide ring resonator, such that an optical signal in the first waveguide ring resonator optically couples into the one or more second waveguide ring resonators. The one or more second waveguide ring resonators is configured such that when the optical signal resonates within the first waveguide ring resonator and the one or more second waveguide ring resonators, the optical signal within the first waveguide ring resonator is suppressed. |
| FILED | Wednesday, January 06, 2021 |
| APPL NO | 17/142929 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/30 (20130101) H01S 3/063 (20130101) H01S 3/083 (20130101) H01S 3/08018 (20130101) Original (OR) Class H01S 5/1071 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11431368 | Medard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); National University of Ireland, Maynooth (Maynooth, Ireland) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); National University of Ireland, Maynooth (Maynooth, Ireland) |
| INVENTOR(S) | Muriel Medard (Belmont, Massachusetts); Kenneth R. Duffy (Dublin, Ireland); Amit Solomon (Cambridge, Massachusetts); Alejandro Cohen (Brookline, Massachusetts) |
| ABSTRACT | Described are concepts, systems, devices and methods that enhance decoding performance of channels subject to correlated noise. The concepts, systems, devices and methods can be used with any combination of codes, code-rates and decoding techniques. In embodiments, a continuous realization of effective noise is estimated from a lead channel by subtracting its decoded output from its received signal. This estimate is then used to improve the accuracy of decoding of an otherwise orthogonal channel that is experiencing correlated effective noise. In this approach, channels aid each other through the post-decoding provision of estimates of effective noise. In some embodiments, the lead channel is not pre-determined, but is chosen dynamically based on which of a plurality of decoders completes first, or using soft information including an estimate of effective noise that is least energetic or most likely to have occurred. |
| FILED | Tuesday, March 16, 2021 |
| APPL NO | 17/202860 |
| ART UNIT | 2646 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Transmission H04B 1/123 (20130101) Original (OR) Class H04B 1/1027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11431421 | Kobold |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Michael Kobold (Indialantic, Florida) |
| ABSTRACT | A system for improving acoustic communications in a shallow-water environment is provided. The system includes a pump, an elongated inflatable bladder and an acoustic communication modem and transducer. The pump forces water through the bladder, which creates a pumping current. This pumping current drives the sound speed profile up and down vertically, resulting in changes to shallow-water acoustic communication shadows and resultant improved acoustic communication. The bladder may be biased to return to a coiled shape after operation of the pump. The system may be mounted on a turntable to be able to direct the bladder in a preferred direction. Equipment can be attached to the end of the bladder and be transported with the uncoiling and recoiling of the bladder. |
| FILED | Wednesday, December 18, 2019 |
| APPL NO | 16/718515 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Transmission H04B 11/00 (20130101) Original (OR) Class H04B 13/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11431548 | Hartley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARCHITECTURE TECHNOLOGY CORPORATION (Eden Prairie, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Timothy E. Hartley (Eden Prairie, Minnesota); Ranga S. Ramanujan (Medina, Minnesota); Clint M. Sanders (Plymouth, Minnesota) |
| ABSTRACT | Embodiments for a method of implementing multiple domains in a network switching device are disclosed. The method includes assigning a plurality of hardware ports to a plurality of domains. Ports are assigned to at least two of the plurality of domains, and none of the ports are concurrently assigned to multiple domains. The method also includes loading rules for forwarding packets between the plurality of ports into a data plane. The rules direct the data plane to forward only between ports in a common domain of the plurality of domains. The method also includes assuring that a packet received at any port assigned to a first domain is not sent in legible form from any port assigned to a second domain if an error causes the data plane to forward or request forwarding the packet to any port assigned to a second domain. |
| FILED | Monday, March 09, 2020 |
| APPL NO | 16/813142 |
| ART UNIT | 2425 — Cable and Television |
| CURRENT CPC | Electric Digital Data Processing G06F 9/45558 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 12/4641 (20130101) H04L 29/06585 (20130101) Original (OR) Class H04L 45/04 (20130101) H04L 47/785 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11425870 | Goudey |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Clifford A. Goudey (Newburyport, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Clifford A. Goudey (Newburyport, Massachusetts) |
| ABSTRACT | An apparatus for attaching vegetative propagules to a longline that may include a clip portion having a curved area sized to receive a stem of a vegetative propagule and having an opening to the curved area smaller than the curved area to secure the vegetative propagule in the curved area; a tapered barrel that is inserted into a longline; and a rigid connection by a tower between the clip portion and the tapered barrel. Also disclosed is a macroalgae farm including the apparatus for attaching vegetative propagules to a longline. |
| FILED | Monday, September 02, 2019 |
| APPL NO | 16/558294 |
| ART UNIT | 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 9/128 (20130101) A01G 33/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426717 | Moulton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| INVENTOR(S) | Staci A. Moulton (Broomfield, Colorado); Alan W. Weimer (Niwot, Colorado) |
| ABSTRACT | Structures, catalysts, and reactors suitable for use for a variety of applications, including gas-to-liquid and coal-to-liquid processes and methods of forming the structures, catalysts, and reactors are disclosed. The catalyst material can be deposited onto an inner wall of a microtubular reactor and/or onto porous support structures using atomic layer deposition techniques. |
| FILED | Tuesday, November 17, 2015 |
| APPL NO | 15/527630 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0093 (20130101) B01J 23/75 (20130101) B01J 35/006 (20130101) B01J 35/0013 (20130101) B01J 35/023 (20130101) B01J 35/1014 (20130101) B01J 37/08 (20130101) B01J 37/34 (20130101) B01J 37/0221 (20130101) Original (OR) Class B01J 2219/00792 (20130101) B01J 2219/00801 (20130101) B01J 2219/00835 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 2/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427467 | Siriwardane et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Energy, United States Department of (Washington, District of Columbia) |
| ASSIGNEE(S) | Energy, United States Department of (Washington, District of Columbia) |
| INVENTOR(S) | Ranjani Siriwardane (Morgantown, West Virginia); William Benincosa (Chicago, Illinois); Jarrett Riley (Morgantown, West Virginia) |
| ABSTRACT | The invention provides a calcined Fex—Aly—Oz based catalyst for the decomposition of hydrocarbons such as methane to produce hydrogen and carbon. The catalyst comprises iron oxide mixed with aluminum oxide and calcined at temperatures above 1100° C., where Fex—Aly—Oz is a chemical composition with x>0.1, y>0.1, z≥0 and 0<x/y<200. Reaction of the calcined Fex—Aly—Oz catalyst with methane generates a product stream comprising at least 40 vol. % H2 and carbon. In an embodiment, carbon is separated from the catalyst and the catalyst is reused for continuous methane decomposition to produce H2. |
| FILED | Thursday, March 21, 2019 |
| APPL NO | 16/360916 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/002 (20130101) B01J 23/745 (20130101) B01J 37/08 (20130101) B01J 2523/31 (20130101) B01J 2523/842 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/26 (20130101) Original (OR) Class C01B 2203/049 (20130101) C01B 2203/0277 (20130101) C01B 2203/1241 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427468 | Witwer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ONBOARD DYNAMICS, INC. (Bend, Oregon) |
| ASSIGNEE(S) | Onboard Dynamics LLC (Bend, Oregon) |
| INVENTOR(S) | Jeffrey G. Witwer (Bend, Oregon); Steven D. Westberg (Bend, Oregon) |
| ABSTRACT | An integrated hydrogen generator and compressor (200) that includes a combined engine compressor (collectively 109, 110, 111) and steam-methane reformer (104) to produce high-pressure hydrogen from natural gas (methane). The reformer (104) combines methane, water, and heat under high pressure in the presence of an appropriate catalyst, to produce hydrogen utilizing waste heat from combustion cylinders of the combined engine compressor (collectively 109, 110, 111). Compression serves to pressurize two different gases (methane and hydrogen) in different compression cylinders including the compression cylinders (109a, 109b, 109c) of the combined engine compressor (collectively 109, 110, 111) alternatively and/or optionally combined with internal combustion engine (310) and/or gas compressor(s) (410) that are integrated thermally and via communication of compressed gases. |
| FILED | Thursday, March 29, 2018 |
| APPL NO | 16/500931 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 3/38 (20130101) Original (OR) Class C01B 2203/0233 (20130101) C01B 2203/0811 (20130101) C01B 2203/1241 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427480 | Hatchett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (Las Vegas, Nevada) |
| ASSIGNEE(S) | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA (Las Vegas, Nevada) |
| INVENTOR(S) | David W. Hatchett (Las Vegas, Nevada); Kenneth R. Czerwinski (Seattle, Washington); Katherine Luebke (Las Vegas, Nevada); Cassara Higgins (Las Vegas, Nevada) |
| ABSTRACT | Described are methods for the recovery of uranium from uranium hexafluoride dissolved directly into ionic liquids. |
| FILED | Friday, March 29, 2019 |
| APPL NO | 17/438112 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 43/025 (20130101) C01G 43/063 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/85 (20130101) C01P 2002/88 (20130101) C01P 2004/03 (20130101) Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor C25C 3/34 (20130101) C25C 7/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427536 | Miyake et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| INVENTOR(S) | Garret Miyake (Fort Collins, Colorado); Bin Liu (Boulder, Colorado); Chern-Hooi Lim (Boulder, Colorado) |
| ABSTRACT | In one aspect, the invention provides a method of promoting a carbon-sulfur bond forming reaction. In certain embodiments, the reaction comprises cross-coupling of a(n) (hetero)aryl halide with a thiol to form the carbon-sulfur bond, wherein the method is promoted by light irradiation in the absence of a photocatalyst. In other embodiments, the cross-coupling reaction can be promoted through visible light irradiation, including sunlight. |
| FILED | Wednesday, June 27, 2018 |
| APPL NO | 16/019914 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/123 (20130101) B01J 19/127 (20130101) Acyclic or Carbocyclic Compounds C07C 319/14 (20130101) Original (OR) Class C07C 319/14 (20130101) C07C 319/14 (20130101) C07C 319/14 (20130101) C07C 319/14 (20130101) C07C 319/14 (20130101) C07C 319/14 (20130101) C07C 319/14 (20130101) C07C 321/30 (20130101) C07C 323/09 (20130101) C07C 323/20 (20130101) C07C 323/21 (20130101) C07C 323/22 (20130101) C07C 323/37 (20130101) C07C 323/62 (20130101) C07C 2603/24 (20170501) C07C 2603/50 (20170501) Heterocyclic Compounds C07D 213/70 (20130101) C07D 215/36 (20130101) C07D 235/28 (20130101) C07D 239/38 (20130101) C07D 277/74 (20130101) C07D 285/16 (20130101) C07D 285/22 (20130101) C07D 311/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427757 | Wheeler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Lance Michael Wheeler (Golden, Colorado); Nathan Richard Neale (Denver, Colorado); Nicholas Charles Anderson (Dallas, Texas); Matthew Peter Hautzinger (Arlington Heights, Illinois); Taylor Sierra Bliss (Jacksonville, Florida) |
| ABSTRACT | The present disclosure relates to a perovskite sheet that includes two outer layers, each including A′X′; and a first layer that includes BX2, where B is a first cation, A′ is a second cation, X is a first anion, X′ is a second anion, and the first BX2 layer is positioned between the two outer layers. |
| FILED | Friday, February 08, 2019 |
| APPL NO | 16/271358 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 21/006 (20130101) C01G 21/16 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/34 (20130101) C01P 2002/72 (20130101) C01P 2002/82 (20130101) C01P 2004/04 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/24 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 11/665 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427918 | Choi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kyoung-Shin Choi (Fitchburg, Wisconsin); John James Roylance (Madison, Wisconsin); Stephen R. Kubota (Madison, Wisconsin) |
| ABSTRACT | Electrochemical cells and photoelectrochemical cells for the reduction of furfurals are provided. Also provided are methods of using the cells to carry out the reduction reactions. Using the cells and methods, furfurals can be converted into furan alcohols or linear ketones. |
| FILED | Thursday, April 15, 2021 |
| APPL NO | 17/231137 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/55 (20210101) C25B 3/05 (20210101) C25B 3/07 (20210101) C25B 3/21 (20210101) C25B 3/25 (20210101) Original (OR) Class C25B 11/04 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/133 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11428174 | Flowers |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Daniel L. Flowers (San Leandro, California) |
| ABSTRACT | The present disclosure relates to a system for controlling ignition of an air/fuel mixture intake charge directed into an internal combustion engine. The system may have a longitudinally movable inner cylinder liner configured to fit within a cylinder wall portion of an internal combustion engine, and able to receive a piston of the engine therein. A portion of the inner cylinder liner defines an internal volume forming a combustion chamber, and the internal volume controls a compression ratio of the cylinder. The system also has a cylinder head assembly operatively associated with the inner cylinder liner and able to move linearly to cause longitudinal displacement of the inner cylinder liner relative to the cylinder wall portion. This enables the volume of the combustion chamber to be further varied, to thus further vary the compression ratio. |
| FILED | Friday, February 05, 2021 |
| APPL NO | 17/168933 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Internal-combustion Piston Engines; Combustion Engines in General F02B 75/38 (20130101) F02B 75/041 (20130101) F02B 2075/025 (20130101) Controlling Combustion Engines F02D 15/04 (20130101) Original (OR) Class F02D 35/02 (20130101) Cylinders, Pistons or Casings, for Combustion Engines; Arrangements of Sealings in Combustion Engines F02F 1/004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11428413 | Berry et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Jonathan Dwight Berry (Simpsonville, South Carolina); Michael John Hughes (State College, Pennsylvania); James Scott Flanagan (Simpsonville, South Carolina) |
| ABSTRACT | The present disclosure is directed to a fuel injection module for a segmented annular combustion system. The fuel injection module includes a housing body, a fuel nozzle portion, and at least one fuel injection lance. The fuel nozzle portion is fluidly coupled to a fuel nozzle plenum within the housing body, and the at least one fuel injection lance is fluidly coupled to an injector fuel plenum within the housing body. In some cases, the fuel nozzle portion is a bundled tube fuel nozzle having one or more subsets of tubes. The fuel injection lances are positioned along a radial side of the housing body or circumferentially between two subsets of tubes. Liquid fuel cartridges extend through the fuel nozzle portion, the fuel injection lances, or both. |
| FILED | Tuesday, March 21, 2017 |
| APPL NO | 15/464406 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/28 (20130101) Original (OR) Class F23R 3/46 (20130101) F23R 3/286 (20130101) F23R 2900/00001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11428440 | Xia et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Zijing Xia (Chicago, Illinois); Hao-Cheng Yang (Westmont, Illinois); Zhaowei Chen (Downers Grove, Illinois); Seth B. Darling (Chicago, Illinois) |
| ABSTRACT | A porphyrine organic framework (“POF”) material is introduced with a one-pot method for photothermal material fabrication. The POF material may be deposited on a support scaffold by reacting a pyrrole by acid-catalyzed dehydration forming a plurality of porphyrin-based covalent organic frameworks particles on the support scaffold. |
| FILED | Thursday, May 09, 2019 |
| APPL NO | 16/407841 |
| ART UNIT | 1759 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Heterocyclic Compounds C07D 487/22 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 5/14 (20130101) Solar Heat Collectors; Solar Heat Systems F24S 70/10 (20180501) Original (OR) Class F24S 70/65 (20180501) F24S 2080/011 (20180501) F24S 2080/013 (20180501) F24S 2080/017 (20180501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11428623 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | West Virginia University Board of Governors on behalf of West Virginia University (Morgantown, West Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xingbo Liu (Morgantown, West Virginia); Tianliang Zhao (Shanghai, China PRC); Greg Collins (Morgantown, West Virginia) |
| ABSTRACT | A high temperature corrosion sensor is provided having (i) a housing having an external wall and an internal wall, the internal wall of the housing forming a chamber of the housing, (ii) a stainless steel tube inserted into the chamber, (iii) a ceramic tube wherein at least a portion of the ceramic tube is inserted into the stainless steel tube, (iv) an airflow tube that extends through the chamber, and (v) a sensor probe having a first working electrode, a second working electrode, a reference electrode, a positive electrical resistance, a negative electrical resistance, and a thermocouple, wherein at least a portion of each are encapsulated into a ceramic casting that is located at one end of the housing. Methods of measuring corrosion within a power plant environment are provided. |
| FILED | Friday, December 18, 2020 |
| APPL NO | 17/247648 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 17/04 (20130101) Original (OR) Class G01N 17/006 (20130101) G01N 27/021 (20130101) G01N 27/041 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11428831 | Schmidt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Andrea Schmidt (Livermore, California); Maurice B. Aufderheide (Livermore, California); David Neal Fittinghoff (Livermore, California); James M. Hall (Livermore, California); Yuri Podpaly (Hayward, California) |
| ABSTRACT | The present disclosure relates to a time-gated fast neutron transmission radiography system and method. The system makes use of a pulsed neutron source for producing neutrons in a plurality of directions, with at least a subplurality of the neutrons being directed at an object to be imaged. The system also includes a neutron detector system configured to time-gate the detection of neutrons emitted from the pulsed neutron source to within a time-gated window. |
| FILED | Monday, August 05, 2019 |
| APPL NO | 16/532052 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 3/06 (20130101) Original (OR) Class Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/06 (20130101) H05H 3/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11429865 | Patton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Robert M. Patton (Oak Ridge, Tennessee); Steven R. Young (Oak Ridge, Tennessee); Derek C. Rose (Oak Ridge, Tennessee); Thomas P. Karnowski (Oak Ridge, Tennessee); Seung-Hwan Lim (Oak Ridge, Tennessee); Thomas E. Potok (Oak Ridge, Tennessee); J. Travis Johnston (Oak Ridge, Tennessee) |
| ABSTRACT | A system and method design and optimize neural networks. The system and method include a data store that stores a plurality of gene vectors that represent diverse and distinct neural networks and an evaluation queue stored with the plurality of gene vectors. Secondary nodes construct, train, and evaluate the neural network and automatically render a plurality of fitness values asynchronously. A primary node executes a gene amplification on a select plurality of gene vectors, a crossing-over of the amplified gene vectors, and a mutation of the crossing-over gene vectors automatically and asynchronously, which are then transmitted to the evaluation queue. The process continuously repeats itself by processing the gene vectors inserted into the evaluation queue until a fitness level is reached, a network's accuracy level plateaus, a processing time period expires, or when some stopping condition or performance metric is met or exceeded. |
| FILED | Friday, February 01, 2019 |
| APPL NO | 16/265252 |
| ART UNIT | 2128 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/082 (20130101) G06N 3/086 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11430577 | Peterson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| INVENTOR(S) | Luc Peterson (Livermore, California); Scott T. Brandon (Livermore, California); John E. Field (Livermore, California); Kelli Denise Humbird (Livermore, California); Steve Langer (Livermore, California); Ryan Charles Nora (Livermore, California); Brian K. Spears (Livermore, California) |
| ABSTRACT | Methods, devices and system for asymmetric inertial confinement fusion are disclosed. One method includes a fixing in position a target capsule comprising an inertial confinement fusion fuel, where the target capsule is substantially spherical. The method further includes for applying an oscillatory compression to the target capsule. The oscillatory compression includes compression at a first time in a radial direction orthogonal to a diametric axis of the target capsule, and compression at a second time along the diametric axis to drive the target capsule into driven into an ovoid shape. The oval shaped target can implode upon being further driven at a third time. |
| FILED | Wednesday, August 02, 2017 |
| APPL NO | 16/090807 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Fusion Reactors G21B 1/03 (20130101) Original (OR) Class G21B 1/19 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11430900 | Holman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Zachary Holman (Phoenix, Arizona); Kathryn Fisher (Scottsdale, Arizona); Xiaodong Meng (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Zachary Holman (Phoenix, Arizona); Kathryn Fisher (Scottsdale, Arizona); Xiaodong Meng (Tempe, Arizona) |
| ABSTRACT | A photovoltaic module comprises a plurality of photovoltaic cells, and a polymeric film positioned on an incident light side of the plurality of photovoltaic cells, wherein the polymeric film transmits a range of wavelengths of the incident light spectrum and specularly reflects wavelengths outside of the range. An encapsulant layer is in contact with the polymeric film. The polymeric film may have a first surface area larger than a second surface area of the layer of photovoltaic cells. The polymeric film may have one or more through-holes so that encapsulant can penetrate through the through-holes at elevated temperature during lamination thereby bonding to a front glass of the photovoltaic module. |
| FILED | Tuesday, August 22, 2017 |
| APPL NO | 15/683254 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/056 (20141201) H01L 31/0481 (20130101) H01L 31/1876 (20130101) H01L 31/02162 (20130101) H01L 31/02167 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/52 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/50 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11430974 | Oakes et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio) |
| ASSIGNEE(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Landon J. Oakes (Cambridge, Massachusetts); Haley L. Orler (Bridgeville, Pennsylvania); Stuart D. Hellring (Pittsburgh, Pennsylvania) |
| ABSTRACT | The present invention is directed toward a coating system for electrodepositing a battery electrode coating onto a foil substrate, the system comprising a tank structured and arranged to hold an electrodepositable coating composition; a feed roller positioned outside of the tank structured and arranged to feed the foil into the tank; at least one counter electrode positioned inside the tank, the counter electrode in electrical communication with the foil during operation of the system to thereby deposit the battery electrode coating onto the foil; and an in-line foil drier positioned outside the tank structured and arranged to receive the coated foil from the tank. Also disclosed are methods for electrocoating battery electrode coatings onto conductive foil substrates, coated foil substrates, and electrical storage devices comprising the coated foil substrates. |
| FILED | Friday, May 17, 2019 |
| APPL NO | 16/415061 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 13/16 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/28 (20130101) H01G 11/50 (20130101) H01G 11/86 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/0435 (20130101) H01M 4/0457 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11430994 | Xiao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan); BROWN UNIVERSITY (Providence, Rhode Island) |
| ASSIGNEE(S) | GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan); BROWN UNIVERSITY (Providence, Rhode Island) |
| INVENTOR(S) | Xingcheng Xiao (Troy, Michigan); Binsong Li (Troy, Michigan); Huajian Gao (Providence, Rhode Island); Kai Guo (Providence, Rhode Island) |
| ABSTRACT | Double-layered protective coatings for lithium metal electrodes, as well as methods of formation relating thereto, are provided. The negative electrode assembly includes an electroactive material layer including lithium metal and a protective dual-layered coating. The protective dual-layered coating includes a polymeric layer disposed on a surface of the electroactive material layer and an inorganic layer disposed on an exposed surface of the polymeric layer. The polymeric layer has an elastic modulus of greater than or equal to about 0.01 GPa to less than or equal to about 410 GPa. The inorganic layer has an elastic modulus of greater than or equal to about 10 GPa to less than or equal to about 1000 GPa. |
| FILED | Friday, December 28, 2018 |
| APPL NO | 16/234873 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/134 (20130101) H01M 4/366 (20130101) H01M 4/382 (20130101) H01M 4/0402 (20130101) H01M 4/628 (20130101) Original (OR) Class H01M 4/1395 (20130101) H01M 10/052 (20130101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11431016 | Surendranath et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | FuelCell Energy, Inc. (Danbury, Connecticut) |
| ASSIGNEE(S) | FuelCell Energy, Inc. (Danbury, Connecticut) |
| INVENTOR(S) | Arun Surendranath (Danbury, Connecticut); Abdelkader Hilmi (Bethel, Connecticut); Chao-Yi Yuh (New Milford, Connecticut) |
| ABSTRACT | A binder solution for an electrolyte matrix for use with molten carbonate fuel cells is provided. The binder solution includes a first polymer with a molecular weight of less than about 150,000 and a second binder with a molecular weight of greater than about 200,000. The binder solution produces an electrolyte matrix with improved flexibility, matrix particle packing density, strength, and pore structure. |
| FILED | Wednesday, April 12, 2017 |
| APPL NO | 15/486160 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Compositions of Macromolecular Compounds C08L 33/10 (20130101) C08L 2203/20 (20130101) C08L 2205/02 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/142 (20130101) Original (OR) Class H01M 8/145 (20130101) H01M 8/0295 (20130101) H01M 2008/147 (20130101) H01M 2300/0051 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11431208 | Tangudu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | HAMILTON SUNDSTRAND CORPORATION (Charlotte, North Carolina) |
| INVENTOR(S) | Jagadeesh Tangudu (South Windsor, Connecticut); Beata I. Wawrzyniak (South Windsor, Connecticut); John A. Sharon (West Hartford, Connecticut); James T. Beals (West Hartford, Connecticut); Tahany Ibrahim El-Wardany (Bloomfield, Connecticut); Wayde R. Schmidt (Pomfret Center, Connecticut) |
| ABSTRACT | An electrical device includes an electromagnetic component configured to generate a magnetic flux. The electromagnetic component includes a soft magnetically-conductive material configured to pass magnetic flux therethrough along a flux path. The soft magnetically-conductive material includes at least one grain oriented portion having metal grains that are oriented parallel with respect to the magnetic flux. |
| FILED | Monday, March 16, 2020 |
| APPL NO | 16/820438 |
| ART UNIT | 2832 — Semiconductors/Memory |
| CURRENT CPC | Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 8/12 (20130101) C21D 9/0068 (20130101) Alloys C22C 38/02 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 27/25 (20130101) H01F 41/0213 (20130101) Dynamo-electric Machines H02K 1/02 (20130101) Original (OR) Class H02K 1/16 (20130101) H02K 1/2766 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11426094 | Trzasko |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Joshua D. Trzasko (Rochester, Minnesota) |
| ABSTRACT | Methods for reconstructing images of a subject from data acquired with a medical imaging system, such as a magnetic resonance imaging (“MRI”) system, are described. In general, the image reconstructions implement a primal-dual optimization strategy that, in each iteration, stochastically updates a dual variable. |
| FILED | Friday, April 06, 2018 |
| APPL NO | 16/498973 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5608 (20130101) G01R 33/5611 (20130101) Electric Digital Data Processing G06F 17/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426197 | Swaney et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| INVENTOR(S) | Philip J. Swaney (Nashville, Tennessee); Robert J. Webster, III (Nashville, Tennessee) |
| ABSTRACT | A steerable surgical needle (10) includes an elongated needle shaft (12), a beveled tip portion (14), and a flexural element (16) that connects the needle shaft (12) with the tip portion (14) and permits the tip portion to deflect relative to the needle shaft. A method for steering the surgical needle (10) through tissue includes the steps of advancing the needle in the body tissue to induce tip flexure which causes the needle to follow a curved trajectory, and rotating the needle about its longitudinal axis in place, without advancement, to remove the tip flexure. |
| FILED | Wednesday, October 30, 2019 |
| APPL NO | 16/668291 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/3403 (20130101) Original (OR) Class A61B 17/3417 (20130101) A61B 2017/003 (20130101) A61B 2017/3454 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426360 | Jabbarzadeh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina) |
| ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina); TIGHitco, Inc. (North Charleston, South Carolina) |
| INVENTOR(S) | Ehsan Jabbarzadeh (Columbia, South Carolina); Sara Eslambolchimoghadam (Columbia, South Carolina) |
| ABSTRACT | Methods and compositions are described for use in encouraging angiogenesis and skin healing as may be utilized in wound treatment as well as in encouragement of angiogenesis in disease. Compositions include an effective amount of a natural pimarane diterpenoid extract of Hymenocrater elegans, or a derivative, analogue, or homolog thereof. Compounds based upon this natural extract have been found to be highly effective in vascular formation and skin closure while exhibiting low toxicity. |
| FILED | Monday, September 23, 2019 |
| APPL NO | 16/578688 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/05 (20130101) A61K 31/047 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426450 | Khademhosseini et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Alireza Khademhosseini (Cambridge, Massachusetts); Rahmi Oklu (Scottsdale, Arizona) |
| ABSTRACT | This disclosure relates to methods of using shear-thinning compositions in the treatment of a vascular disorders, cancers, infections, abscesses, and fistulas. |
| FILED | Monday, August 02, 2021 |
| APPL NO | 17/392088 |
| ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0019 (20130101) A61K 38/39 (20130101) Original (OR) Class A61K 47/02 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426490 | Banquy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VALORISATION RECHERCHE, LIMITED PARTNERSHIP (Montréal, Canada); VALORISATION HSJ, LIMITED PARTNERSHIP (Montréal, Canada); CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Valorisation-Recherche, Limited Partnership (Montreal, Canada); Valorisation HSJ, Limited Partnership (Montreal, Canada); Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Xavier Banquy (Saint-Laurent, Canada); Jimmy Faivre (Villeurbanne, France); Buddha Ratna Shrestha (Montreal, Canada); Krzysztof Matyjaszewski (Pittsburgh, Pennsylvania); Joanna Burdynska (Berkeley, California); Florina Moldovan (Montréal, Canada) |
| ABSTRACT | A mixture of polymers with lubricating properties is provided. The polymer can be used to produce a lubricating fluid. They can also be born on a surface or embedded in a porous material. This mixture of polymers comprises (a) a pharmaceutically acceptable bottle-brush polymer comprising a backbone with polymeric pendant chains, and (b) a pharmaceutically acceptable linear polymer. In the lubricating fluid, the bottle-brush polymer and the linear polymer are dissolved together in a pharmaceutically acceptable solvent. |
| FILED | Monday, March 01, 2021 |
| APPL NO | 17/189144 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/16 (20130101) A61L 27/16 (20130101) A61L 27/50 (20130101) Original (OR) Class A61L 31/10 (20130101) A61L 31/14 (20130101) A61L 2400/06 (20130101) A61L 2400/10 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0072 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/14 (20130101) C08F 220/14 (20130101) C08F 220/20 (20130101) C08F 230/02 (20130101) C08F 230/085 (20200201) C08F 265/06 (20130101) C08F 265/06 (20130101) C08F 2438/01 (20130101) Compositions of Macromolecular Compounds C08L 5/08 (20130101) C08L 5/08 (20130101) C08L 33/12 (20130101) C08L 51/003 (20130101) C08L 51/003 (20130101) Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition C10M 107/44 (20130101) C10M 107/48 (20130101) C10M 173/02 (20130101) C10M 2201/02 (20130101) C10M 2217/003 (20130101) C10M 2225/025 (20130101) Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions C10N 2040/50 (20200501) C10N 2050/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427474 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Weigu Li (Austin, Texas); Donglei Fan (Austin, Texas) |
| ABSTRACT | Disclosed herein are dendritically porous three-dimensional structures, including hierarchical dendritically porous three-dimensional structures. The structures include metal foams and graphite structures, and are useful in energy storage devices as well as chemical catalysis. |
| FILED | Thursday, March 08, 2018 |
| APPL NO | 16/491748 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/205 (20170801) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/85 (20130101) C01P 2004/03 (20130101) C01P 2006/10 (20130101) C01P 2006/12 (20130101) C01P 2006/16 (20130101) C01P 2006/40 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/26 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 1/003 (20130101) C25D 1/006 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/24 (20130101) H01G 11/36 (20130101) H01G 11/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427817 | Josephs et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Eric Josephs (Durham, North Carolina); Dewran Kocak (Durham, North Carolina); Piotr Marszalek (Durham, North Carolina); Charles A. Gersbach (Durham, North Carolina) |
| ABSTRACT | Disclosed herein are optimized guide RNAs (gRNAs) that have increased target binding specificity and reduced off-target binding. Further disclosed herein are methods of designing and using the optimized gRNAs. |
| FILED | Thursday, August 25, 2016 |
| APPL NO | 15/754861 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) Original (OR) Class C12N 15/111 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 15/10 (20190201) G16B 15/30 (20190201) G16B 25/00 (20190201) G16B 30/10 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427856 | Seelig et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Georg Seelig (Seattle, Washington); Richard Muscat (London, United Kingdom); Alexander B. Rosenberg (Seattle, Washington) |
| ABSTRACT | Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens. |
| FILED | Monday, November 08, 2021 |
| APPL NO | 17/521263 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6855 (20130101) C12Q 1/6855 (20130101) C12Q 2563/179 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427865 | Ismagilov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Rustem F Ismagilov (Altadena, California); Jacob T Barlow (Pasadena, California); Said R. Bogatyrev (Pasadena, California) |
| ABSTRACT | Provided herein are methods and systems for absolute quantification of a target 16S rRNA and/or of a target prokaryotic taxon, based on amplifying and sequencing a same 16S rRNA recognition segment in which target 16S rRNA conserved regions flank 16S rRNA variable regions, conserved and variable among a plurality of sample 16S rRNAs and/or of a sample prokaryotic taxon of higher taxonomic rank with respect to the target taxon. In the methods and systems, absolute abundance of the a plurality of sample 16S rRNAs and/or of the sample prokaryotic taxon detected by the amplifying, is multiplied by the relative abundance of the target 16S rRNA and/or of a target prokaryotic taxon detected by the sequencing to provide the absolute quantification in accordance with method and systems of the disclosure. |
| FILED | Monday, July 13, 2020 |
| APPL NO | 16/927496 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class C12Q 1/6888 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11427887 | Ibrahim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Malek Y. S. Ibrahim (Urbana, Illinois); Scott E. Denmark (Champaign, Illinois) |
| ABSTRACT | Disclosed herein is a method for extracting precious metals from supported catalysts. The precious metal in one embodiment is rhodium. The supported catalyst may be from equipment, such as a used catalytic converter. The method is carried out at low temperature, and does not require harsh conditions, such as the use of a strong acid. The method involves contacting the catalytic material with a polar molecule and a reactive gas. |
| FILED | Monday, November 26, 2018 |
| APPL NO | 16/199568 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/94 (20130101) B01D 2255/1025 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 3/22 (20130101) C22B 3/32 (20210501) C22B 3/282 (20210501) C22B 3/1625 (20130101) C22B 5/12 (20130101) C22B 7/009 (20130101) C22B 11/04 (20130101) Original (OR) Class C22B 11/048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11428572 | Dumont et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | YouV Labs, Inc. (New York, New York) |
| ASSIGNEE(S) | YouV Labs, Inc. (New York, New York) |
| INVENTOR(S) | Emmanuel Dumont (New York, New York); Peter Kaplan (Montclair, New Jersey) |
| ABSTRACT | Methods of accurately estimating erythemaly-weighted UV exposure, such as the UV Index, and sensors adapted for the same. |
| FILED | Monday, December 28, 2020 |
| APPL NO | 17/135078 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/16 (20130101) G01J 1/44 (20130101) G01J 1/429 (20130101) Original (OR) Class G01J 1/0488 (20130101) G01J 2001/444 (20130101) G01J 2001/1657 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11428588 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Shiyi Liu (Tempe, Arizona); Junseok Chae (Scottsdale, Arizona) |
| ABSTRACT | Fully-passive sensor systems that receive an input electromagnetic signal and return an output electromagnetic signal are described. The sensor systems can be used to measure pressure in biological or non-biological systems. |
| FILED | Monday, March 30, 2020 |
| APPL NO | 16/834726 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/031 (20130101) A61B 5/032 (20130101) A61B 5/0048 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/086 (20130101) Original (OR) Class G01L 9/0002 (20130101) G01L 2009/0066 (20130101) G01L 2009/0069 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11428657 | Meng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Ellis F. Meng (Los Angeles, California); Lawrence Yu (Los Angeles, California) |
| ABSTRACT | A sensor for measuring electrochemical impedance includes a primary circuit that includes a primary electrically conducting coil and a secondary circuit that includes a secondary electrically conducting coil. The primary electrically conducting coil is inductively coupled to the secondary circuit. During operation, the secondary electrically conductive couple has contact electrodes that contact a medium for which the impedance is to be measured. An alternating current source energizes the primary electrically conducting coil during impedance measurements. |
| FILED | Monday, June 05, 2017 |
| APPL NO | 16/306663 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 17/02 (20130101) G01N 27/026 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11428675 | Jones et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Activated Research Company, LLC (Eden Prairie, Minnesota) |
| ASSIGNEE(S) | Activated Research Company, LLC (Eden Prairie, Minnesota) |
| INVENTOR(S) | Andrew Jones (Minneapolis, Minnesota); Tommy Saunders (St. Louis Park, Minnesota); Mike Hofflander (Edina, Minnesota) |
| ABSTRACT | In the present system and method, a conduit from a LC device continuously transports solvent, buffers, and analytes to the inlet of a solvent removal and analyte conversion device which evaporates the solvents, leaving non-volatile analytes for detection. The device comprises a rotating disk. The liquid chromatograph device can be any device using liquid chromatography to separate molecules. The solvents in the LC effluent can include, but are not limited to, water, methanol, acetonitrile, tetrahydrofuran, and acetone. After removal of the volatile components, the non-volatile analytes are converted with a concentrated energy source so that they may be detectable. |
| FILED | Monday, July 29, 2019 |
| APPL NO | 16/524269 |
| ART UNIT | 2853 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/38 (20130101) G01N 30/64 (20130101) Original (OR) Class G01N 2030/027 (20130101) G01N 2030/347 (20130101) G01N 2030/8417 (20130101) G01N 2030/8447 (20130101) G01N 2030/8494 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11428690 | Han et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Miami (Miami, Florida) |
| ASSIGNEE(S) | University of Miami (Miami, Florida) |
| INVENTOR(S) | Xu Han (Coral Gables, Florida); Hossein Shokri Kojori (San Jose, California); Roger M. LeBlanc (Key Biscayne, Florida); Sung Jin Kim (Miami, Florida) |
| ABSTRACT | A plasmonic photoconductor sensing platform is provided. The plasmonic photoconductor sensing platform includes an insulating substrate; a semiconducting film placed on top of the insulating substrate; two metal contacts placed at least in part on the semiconducting film to enforce an electric field; a plurality of plasmonic nanostructures deposited on the semiconducting film and physically separated from metal contacts; an insulating layer, the insulating electrically isolating the plasmonic nanostructures from semiconductor; at least one energy source; and at least one microfluidic channel disposed on the insulating layer. |
| FILED | Tuesday, January 30, 2018 |
| APPL NO | 15/883851 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/554 (20130101) G01N 33/54373 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/09 (20130101) H01L 31/032 (20130101) H01L 31/108 (20130101) H01L 31/165 (20130101) H01L 31/02161 (20130101) H01L 31/022408 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11429862 | Chai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | SRI INTERNATIONAL (Menlo Park, California) |
| INVENTOR(S) | Sek Meng Chai (Princeton, New Jersey); Aswin Nadamuni Raghavan (Princeton, New Jersey); Samyak Parajuli (East Brunswick, New Jersey) |
| ABSTRACT | Techniques are disclosed for training a deep neural network (DNN) for reduced computational resource requirements. A computing system includes a memory for storing a set of weights of the DNN. The DNN includes a plurality of layers. For each layer of the plurality of layers, the set of weights includes weights of the layer and a set of bit precision values includes a bit precision value of the layer. The weights of the layer are represented in the memory using values having bit precisions equal to the bit precision value of the layer. The weights of the layer are associated with inputs to neurons of the layer. Additionally, the computing system includes processing circuitry for executing a machine learning system configured to train the DNN. Training the DNN comprises optimizing the set of weights and the set of bit precision values. |
| FILED | Monday, September 17, 2018 |
| APPL NO | 16/133446 |
| ART UNIT | 2123 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/10 (20130101) G06N 3/084 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11431780 | Halepovic et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AT and T Intellectual Property I, L.P. (Atlanta, Georgia); GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
| ASSIGNEE(S) | AT and T Intellectual Property I, L.P. (Atlanta, Georgia); GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
| INVENTOR(S) | Emir Halepovic (Somerset, New Jersey); Tarun Mangla (Chicago, Illinois); Ellen Zegura (Decatur, Georgia); Mostafa Ammar (Smyrna, Georgia) |
| ABSTRACT | Aspects of the subject disclosure may include, for example, selecting a first video service model according to a server hostname determined according to transport layer security (TLS) transaction data associated with a video session transmitted over a network, calculating a plurality of data delivery statistics from the TLS transaction data according to the first video service model, where the plurality of data delivery statistics includes session-level statistics over the video session, transaction-level statistics over each transaction, and temporal feature statistics over intervals of the video session, determining a quality of experience (QoE) metric for the video session from the plurality of data delivery statistics according to a course-grained data QoE model, and adjusting a first network element of the network responsive to the determining the QoE metric for the video session. Other embodiments are disclosed. |
| FILED | Monday, October 26, 2020 |
| APPL NO | 17/079907 |
| ART UNIT | 2459 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 65/80 (20130101) Original (OR) Class H04L 65/4069 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 11426250 | Ledet et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Eric Howard Ledet (Schenectady, New York); Sydney Marie Caparaso (Monroe, Connecticut); Katerina Vladmirovna Kradinova (Boxborough, Massachusetts); Elizabeth Anne Capogna (Rexford, New York) |
| ABSTRACT | A force measuring apparatus is described. The apparatus includes a force concentrator. The force concentrator is configured to attach to a loadbearing medical device and to produce a transverse force related to an eccentric axial force applied to the loadbearing medical device. A bending stiffness of the force concentrator is different from a bending stiffness of the loadbearing medical device. |
| FILED | Thursday, April 25, 2019 |
| APPL NO | 17/050122 |
| ART UNIT | 3775 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/64 (20130101) A61B 17/80 (20130101) A61B 17/7059 (20130101) A61B 17/8869 (20130101) A61B 90/06 (20160201) Original (OR) Class A61B 2090/064 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11426385 | Hammock et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); United States as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); United States as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Bruce D. Hammock (Davis, California); Sung Hee Hwang (Woodland, California); Ralph W. de Vere White (Sacramento, California); Chong-xian Pan (Sacramento, California); Hongyong Zhang (Sacramento, California); Paul Henderson (Sacramento, California); Ai-Hong Ma (Sacramento, California); Maike Zimmermann (Sacramento, California); Fuli Wang (Xi'an, China PRC) |
| ABSTRACT | Provided are methods and compositions for prolonging survival and/or reducing or inhibiting tumor growth in a cancer subject receiving a regimen of one or more chemotherapeutic agents, an inhibitor of soluble epoxide hydrolase (sEHi) and a non-steroidal anti-inflammatory drug (NSAID) that inhibits one or more enzymes selected from the group consisting of cyclo-oxygenase (“COX”)-1, COX-2, and 5-lipoxygenase (“5-LOX”). The methods and compositions decrease toxicity and/or adverse side effects in subjects receiving a regimen of one or more chemotherapeutic agents. |
| FILED | Tuesday, August 14, 2018 |
| APPL NO | 16/641430 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/415 (20130101) Original (OR) Class A61K 31/7068 (20130101) A61K 33/243 (20190101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 11428763 | Szalai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
| INVENTOR(S) | Veronika Ann Szalai (Monrovia, Maryland); Amit Kumar Agrawal (Rockville, Maryland); Nandita Abhyankar (Rockville, Maryland) |
| ABSTRACT | A planar inverse anapole microresonator includes: an anapolic substrate; an anapolic conductor that includes a first and second inverse anapolic pattern; each inverse anapolic pattern including: a semi annular arm that terminates in a first arm tendril and a second arm tendril; and a medial arm terminating at a medial tip, and the medial tip of the first inverse anapolic pattern opposes the medial tip of the second inverse anapolic pattern, such that the medial tip of the first inverse anapolic pattern is separated from the medial tip of the second inverse anapolic pattern by a medial gap, and the planar inverse anapole microresonator produces a magnetic field region that concentrates a magnetic field localized between the medial tip of the first inverse anapolic pattern and the medial tip of the second inverse anapolic pattern in response to the planar inverse anapole microresonator being subjected to microwave radiation. |
| FILED | Thursday, February 25, 2021 |
| APPL NO | 17/185184 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/46 (20130101) G01R 33/60 (20130101) G01R 33/3456 (20130101) Original (OR) Class Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 7/082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 11429118 | Mangharam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Rahul Mangharam (Philadelphia, Pennsylvania); Yash Vardhan Pant (Philadelphia, Pennsylvania); Houssam Abbas (Philadelphia, Pennsylvania); Rhudii A. Quaye (Philadelphia, Pennsylvania) |
| ABSTRACT | Methods, systems, and computer readable media for controlling a fleet of drones. A method includes receiving a mission specification for each drone of one or more drones, each mission specification including spatio-temporal requirements for the drone. The method includes generating, for each drone, a low-rate trajectory for the drone by performing a robustness maximization of satisfying the mission specification over a low-rate sequence of waypoints for the drone based on a mapping between low-rate trajectories and high-rate trajectories. The method includes transmitting, to each drone, the low-rate trajectory for the drone, causing a local controller of each drone to control the drone by generating a high-rate trajectory using the low-rate trajectory and the mapping between low-rate trajectories and high-rate trajectories. |
| FILED | Thursday, July 18, 2019 |
| APPL NO | 16/515854 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Systems for Controlling or Regulating Non-electric Variables G05D 1/104 (20130101) Original (OR) Class G05D 1/1064 (20190501) Traffic Control Systems G08G 5/003 (20130101) G08G 5/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
General Services Administration (GSA)
| US 11428820 | Barr et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LOCKHEED MARTIN CORPORATION (Bethesda, Maryland) |
| ASSIGNEE(S) | LOCKHEED MARTIN CORPORATION (Bethesda, Maryland) |
| INVENTOR(S) | Keith Stabler Barr (Erie, Colorado); Philip Gatt (Berthoud, Colorado); Derek Andrew Hutton (Golden, Colorado) |
| ABSTRACT | A system for determining airborne light detection and ranging (lidar) installation angles includes an airborne platform, a light detection and ranging (lidar) apparatus, a navigation system and a processor. The airborne platform performs a calibration flight in an orbit. The lidar apparatus is installed on the airborne platform for wind-velocity measurement. The navigation system is on board the airborne platform and measures motion data associated with movements of the airborne platform and generates a navigation signal. The processor determines in real time one or more installation angles of the lidar apparatus on the airborne platform to improve accuracy of the wind-velocity measurement. |
| FILED | Monday, September 16, 2019 |
| APPL NO | 16/572500 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/58 (20130101) G01S 17/89 (20130101) G01S 17/95 (20130101) Original (OR) Class G01S 19/42 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0094 (20130101) G05D 1/0202 (20130101) Electric Digital Data Processing G06F 1/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11430998 | Mata et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | Marianne E. Mata (Dana Point, California); Ali Yousefiani (Tustin, California); Adam J. Lang (Orange, California); Bruno Zamorano Senderos (Huntsville, Alabama); Chellappa Balan (Mason, Ohio) |
| ABSTRACT | A fuel cell stack is described. The fuel cell stack comprises an interconnect assembly comprising a cathode-side interface coupled to an interconnect via a first joint, and an anode-side interface coupled to the interconnect via a second joint, the interconnect assembly having a first coefficient of thermal expansion (CTE) at an interface side of the interconnect assembly. The fuel cell stack further comprises a fuel cell element coupled to the interconnect assembly at the interface side via a hermetic seal, the fuel cell element having a second CTE at the interface side, the first CTE and the second CTE satisfying a predetermined CTE matching condition. |
| FILED | Monday, January 06, 2020 |
| APPL NO | 16/735464 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/0202 (20130101) Original (OR) Class H01M 8/0271 (20130101) H01M 8/2404 (20160201) H01M 2008/1293 (20130101) H01M 2250/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Geospatial Intelligence Agency (NGA)
| US 11430210 | Landry et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Joseph C. Landry (Dallas, Texas); Thomas J. Grabow (Richardson, Texas) |
| ABSTRACT | A system for estimating a Lambertian equivalent reflectance for reflective band imagery is disclosed. In some embodiments, the system estimates an equivalent reflectance and performs atmospheric correction of reflective band imagery without user interaction and accounts for the effect of background reflectance mixing with individual target reflectances. Some of these embodiments use a dark pixel-based technique to improve the characterization of the atmosphere. |
| FILED | Thursday, June 18, 2020 |
| APPL NO | 16/905380 |
| ART UNIT | 2646 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/2823 (20130101) G01J 2003/2826 (20130101) Image Data Processing or Generation, in General G06T 5/003 (20130101) G06T 5/20 (20130101) Image or Video Recognition or Understanding G06V 10/36 (20220101) G06V 10/60 (20220101) G06V 20/13 (20220101) Original (OR) Class G06V 20/194 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11430711 | Lin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Aegis Technology Inc. (Santa Ana, California) |
| ASSIGNEE(S) | Aegis Technology Inc. (Santa Ana, California) |
| INVENTOR(S) | Zhigang Lin (Santa Ana, California); Chunhu Tan (Santa Ana, California); Shuyi Chen (Santa Ana, California) |
| ABSTRACT | A high performance, lead free, Ag paste thermal interface material (TIM) for die attachment and substrate bonding in electronic packaging includes: (i) multiscale silver particles, (ii) metal-coated carbon nanotubes (CNTs), (iii) a polymer, and (iv) a liquid carrier. The multiscale silver particles and metal-coated carbon nanotubes, which function as hybrid filler components, are uniformly dispersed within the TIM composition. The sintered TIM exhibits high density, high mechanical strength, and high thermal conductivity. The components of the liquid carrier including the solvent, binder, surfactants, and thinner are completely evaporated or burned off during sintering. Sintering of the TIM can be conducted at a relatively low temperature, without or with very low (<0.1 MPa) pressure, in open air and without vacuum or inert gas protection. The TIM can be utilized in substrate bonding not only on conventional metal-plated surfaces but also bare Cu substrate surfaces. |
| FILED | Tuesday, November 26, 2019 |
| APPL NO | 16/696105 |
| ART UNIT | 2894 — Semiconductors/Memory |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 30/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/158 (20170801) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 5/00 (20130101) C01G 19/00 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/61 (20130101) C01P 2004/62 (20130101) C01P 2004/64 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/4882 (20130101) H01L 23/3737 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 11430243 | Miller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
| INVENTOR(S) | Derek Miller (Alexandria, Virginia); Thomas J. Graham (Chantilly, Virginia) |
| ABSTRACT | Provided herein are processing systems including a camera that is arranged to capture an image of a delivery item. The system also includes a hardware processor that is operably connected to the camera and that is configured to perform operations that include capturing, using the camera, an image of a delivery item that is undeliverable to an intended recipient or at an intended delivery location, where the image includes an address of the intended recipient. The operations also include embedding, by the hardware processor, processing data with the image of the delivery item to thereby generate an embedded image, and notifying a sender of the delivery item that the delivery item is undeliverable using the embedded image. Also provided herein are related computer readable media and methods of processing delivery items that are undeliverable. |
| FILED | Monday, April 13, 2020 |
| APPL NO | 16/847269 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 3/00 (20130101) Electric Digital Data Processing G06F 3/12 (20130101) Image or Video Recognition or Understanding G06V 10/40 (20220101) G06V 30/10 (20220101) G06V 30/416 (20220101) Original (OR) Class Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 5/22 (20130101) Pictorial Communication, e.g Television H04N 5/232 (20130101) H04N 5/2253 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 11428163 | Parnin |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Francis Parnin (Suffield, Connecticut) |
| ABSTRACT | A two-tier lubrication system may comprise an oil nozzle located in a bearing compartment. A main oil system may be configured to provide oil to the oil nozzle. A scavenge system may be configured to collect oil from the bearing compartment. A valve may be fluidly coupled between the main oil system and the scavenge system. The valve may be configured to actuate between a main flow position and a scavenge flow position. |
| FILED | Tuesday, December 18, 2018 |
| APPL NO | 16/224093 |
| ART UNIT | 3654 — Material and Article Handling |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/20 (20130101) Lubricating of Machines or Engines in General; Lubricating Internal Combustion Engines; Crankcase Ventilating F01M 1/20 (20130101) F01M 11/067 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/06 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2260/98 (20130101) F05D 2270/301 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11431322 | Keane |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Zachary Kyle Keane (Baltimore, Maryland) |
| ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
| INVENTOR(S) | Zachary Kyle Keane (Baltimore, Maryland) |
| ABSTRACT | A capacitively-driven tunable coupler includes a coupling capacitor connecting an open end of a quantum object (i.e., an end of the object that cannot have a DC path to a low-voltage rail, such as a ground node, without breaking the functionality of the object) to an RF SQUID having a Josephson element capable of providing variable inductance and therefore variable coupling to another quantum object. |
| FILED | Friday, July 23, 2021 |
| APPL NO | 17/383779 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/025 (20130101) H01L 39/223 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 11/04 (20130101) Original (OR) Class Pulse Technique H03K 3/38 (20130101) H03K 19/1952 (20130101) H03K 19/017509 (20130101) H03K 19/017545 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, August 30, 2022.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20220830.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page