FedInvent™ Patents
Patent Details for Tuesday, October 04, 2022
This page was updated on Wednesday, October 05, 2022 at 06:07 AM GMT
Department of Health and Human Services (HHS)
| US 11458042 | Magin et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida); SHARKLET TECHNOLOGIES, INC. (Aurora, Colorado) |
| ASSIGNEE(S) | SHARKLET TECHNOLOGIES, INC. (Aurora, Colorado); UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
| INVENTOR(S) | Chelsea Marie Magin (Boulder, Colorado); Anthony B. Brennan (Gainesville, Florida); Bradley Jay Willenberg (Orlando, Florida); Gregory Scott Schultz (Gainesville, Florida); Dylan Burton Neale (Gainesville, Florida) |
| ABSTRACT | Disclosed herein is a multilayered wound dressing comprising a first layer; the first layer including channels that facilitate neovascularization of a wound; and a second layer in contact with the first layer, the second layer having the same or different chemical composition as the first layer; where the second layer comprises at least one surface that has a texture and the direction of the texture is operative to facilitate cell orientation and growth. A method includes forming a first layer of a polymeric material; forming a second layer of the same polymeric material as the first layer on the first layer; and forming a textured surface of the second layer of the same polymeric material as the first layer, the textured surface being operative to facilitate directional cell growth when used in a wound dressing, where the first layer and the second layer are formed using an additive manufacturing process. |
| FILED | Monday, April 25, 2016 |
| APPL NO | 15/568767 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 13/022 (20130101) A61F 13/00029 (20130101) A61F 13/00063 (20130101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/42 (20130101) A61L 15/60 (20130101) A61L 15/64 (20130101) A61L 15/425 (20130101) A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/50 (20130101) A61L 27/58 (20130101) A61L 27/60 (20130101) A61L 2300/414 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11458094 | Ingbar et al. |
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| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | David H. Ingbar (Minneapolis, Minnesota); Timothy P. Rich (Duluth, Minnesota); Robert J. Schumacher (Edina, Minnesota); Jianxun Lei (New Brighton, Minnesota); Maneesh Bhargava (Mendota Heights, Minnesota) |
| ABSTRACT | A pharmaceutical composition for administering directly to the pulmonary tract of a subject includes a salt of triiodothyronine and a pharmaceutically acceptable buffer, adjusted to pH of 5.5-8.5. The composition can be administered prophylactically or therapeutically to a subject to treat lung inflammation or pulmonary edema. |
| FILED | Thursday, January 31, 2019 |
| APPL NO | 16/965095 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0078 (20130101) Original (OR) Class A61K 31/198 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11458097 | Batrakova et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Elena V. Batrakova (Durham, North Carolina); Alexander V. Kabanov (Chapel Hill, North Carolina); Marina Sokolsky (Chapel Hill, North Carolina); Matthew J. Haney (Chapel Hill, North Carolina); Dongfen Yuan (Chapel Hill, North Carolina); Myung Soo Kim (Chapel Hill, North Carolina) |
| ABSTRACT | The present invention relates to compositions comprising exosomes and biological agents and methods of using the compositions for the delivery of biological agents to cells and to subjects. |
| FILED | Thursday, March 30, 2017 |
| APPL NO | 16/089833 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) Original (OR) Class A61K 31/337 (20130101) A61K 31/7088 (20130101) A61K 45/06 (20130101) A61K 47/65 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11458129 | Anderson et al. |
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| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | David J. Anderson (Altadena, California); Moriel Zelikowsky (Pasadena, California); Andrea Choe (Los Angeles, California) |
| ABSTRACT | In some embodiments, methods of inhibiting, ameliorating, reducing the severity of, treating, reducing the likelihood of, or preventing social isolation stress or symptoms thereof in a subject in need thereof are described. In some embodiments, methods of determining a risk of social isolation stress in a subject are described. |
| FILED | Thursday, November 01, 2018 |
| APPL NO | 16/178460 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4545 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 43/00 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11458132 | Schaus et al. |
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| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Scott Edward Schaus (Boston, Massachusetts); Ulla Hansen (Bedford, Massachusetts); Emily Ann York (Allston, Massachusetts); Niranjana Pokharel (Brighton, Massachusetts) |
| ABSTRACT | The present invention is directed to compositions, methods and kits for treatment of cancer, e.g., hepatocellular carcinoma (HCC). In some embodiments, the present invention discloses the use of a small-molecule compounds of Formula (I) to inhibit tubulin acetylation, to inhibit cell migration, or to modulate cell compaction. |
| FILED | Wednesday, September 01, 2021 |
| APPL NO | 17/464260 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4741 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11458136 | Gendelman et al. |
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| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska) |
| ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| INVENTOR(S) | Howard E. Gendelman (Omaha, Nebraska); Benson Edagwa (Omaha, Nebraska) |
| ABSTRACT | The present invention provides prodrugs and methods of use thereof. |
| FILED | Tuesday, April 09, 2019 |
| APPL NO | 16/981325 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5146 (20130101) A61K 31/496 (20130101) A61K 31/505 (20130101) Original (OR) Class A61K 31/536 (20130101) A61K 31/551 (20130101) A61K 31/4439 (20130101) A61K 47/6935 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11458137 | Bennett et al. |
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| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | Anton Bennett (Wilton, Connecticut); Jae-Sung Yi (Hamden, Connecticut) |
| ABSTRACT | The present invention provides compositions and methods of inhibiting tyrosine phosphorylation. In one aspect, a composition comprising a low-dosage tyrosine kinase inhibitor, where the low-dosage tyrosine kinase inhibitor decreases tyrosine phosphorylation, is provided. In another aspect, a method for treating cardiovascular disease or condition associated with a RASopathy having aberrant protein tyrosine phosphorylation is described. Methods for treating congenital heart disease associated with Noonan or Noonan syndrome with multiple lentigines and decreasing aberrant levels of Protein Zero-Related (PZR) tyrosyl phosphorylation are also described. |
| FILED | Thursday, September 19, 2019 |
| APPL NO | 16/575637 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11458141 | Hackam et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | David Joel Hackam (Baltimore, Maryland); Peng Lu (Lutherville Timonium, Maryland); Chhinder P. Sodhi (Columbia, Maryland); Jun O. Liu (Clarksville, Maryland) |
| ABSTRACT | Aryl hydrocarbon receptor (AHR) agonists and their use for treating, preventing, or reducing the risk of necrotizing enterocolitis in premature infants are disclosed. |
| FILED | Friday, May 25, 2018 |
| APPL NO | 16/617247 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/10 (20160801) A23L 33/40 (20160801) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0029 (20130101) A61K 9/0053 (20130101) A61K 31/52 (20130101) Original (OR) Class A61K 31/192 (20130101) A61K 31/404 (20130101) A61K 31/4439 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11458142 | Bazan et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana); UNIVERSITY OF ALCALA DE HENARES (Madrid, Spain) |
| ASSIGNEE(S) | The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana); University of Alcala De Henares (Madrid, Spain); South Rampart Pharma, LLC (New Orleans, Louisiana) |
| INVENTOR(S) | Nicolas Bazan (New Orleans, Louisiana); Hernan Bazan (New Orleans, Louisiana); Julio Alvarez-Builla (Madrid, Spain); Dennis Paul (New Orleans, Louisiana); Carolina Burgos (Madrid, Spain) |
| ABSTRACT | This invention is directed to compositions, methods and kits that can be used for the treatment or amelioration of pain. |
| FILED | Monday, March 12, 2018 |
| APPL NO | 16/641401 |
| ART UNIT | 1699 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/40 (20130101) A61K 31/495 (20130101) A61K 31/4402 (20130101) A61K 31/5375 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 23/00 (20180101) A61P 29/00 (20180101) Acyclic or Carbocyclic Compounds C07C 311/19 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11458151 | Bazin-Lee et al. |
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| FUNDED BY |
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| APPLICANT(S) | INIMMUNE CORPORATION (Missoula, Montana) |
| ASSIGNEE(S) | INIMMUNE CORPORATION (Missoula, Montana) |
| INVENTOR(S) | Helene Bazin-Lee (Stevensville, Montana); George Ettenger (Missoula, Montana); Juhienah Khalaf (Hamilton, Montana); Kendal T. Ryter (Hamilton, Montana) |
| ABSTRACT | Toll-like receptor (TLR) ligands having an allose-based core are stable in aqueous formulation and are useful in treating, preventing, or reducing susceptibility to diseases or conditions mediated by TLRs, such as cancer, infectious disease, allergy, autoimmune disease, sepsis, and ischemia reperfusion. |
| FILED | Tuesday, February 12, 2019 |
| APPL NO | 16/968835 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7008 (20130101) Original (OR) Class A61K 39/35 (20130101) A61K 39/39 (20130101) A61K 45/06 (20130101) A61K 2039/57 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/12 (20130101) C07H 15/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11458158 | Dong et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Yizhou Dong (Dublin, Ohio); Kevin Thomas Love (Boston, Massachusetts); Robert S. Langer (Newton, Massachusetts); Daniel Griffith Anderson (Framingham, Massachusetts); Delai Chen (Cambridge, Massachusetts); Yi Chen (Cambridge, Massachusetts); Arturo Jose Vegas (Belmont, Massachusetts); Akinleye C. Alabi (Ithaca, New York); Yunlong Zhang (Cambridge, Massachusetts) |
| ABSTRACT | Described herein are compounds and compositions characterized, in certain embodiments, by conjugation of various groups, such as lipophilic groups, to an amino or amide group of an amino acid, a linear or cyclic peptide, a linear or cyclic polypeptide, or structural isomer thereof, to provide compounds of the present invention, collectively referred to herein as “APPLs”. Such APPLs are deemed useful for a variety of applications, such as, for example, improved nucleotide delivery. Exemplary APPLs include, but are not limited to, compounds of Formula (I), (II), (III), (IV), (V), and (VI), and salts thereof, as described herein: wherein m, n, p, R′, R1, R2, R3, R4, R5, R8, Z, W, Y, and Z are as defined herein. |
| FILED | Tuesday, May 05, 2020 |
| APPL NO | 16/867291 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/711 (20130101) A61K 31/7105 (20130101) Original (OR) Class A61K 47/22 (20130101) A61K 2121/00 (20130101) Acyclic or Carbocyclic Compounds C07C 229/12 (20130101) C07C 229/22 (20130101) C07C 229/24 (20130101) C07C 229/26 (20130101) C07C 229/36 (20130101) C07C 237/08 (20130101) C07C 237/12 (20130101) C07C 271/22 (20130101) C07C 279/14 (20130101) C07C 323/58 (20130101) Heterocyclic Compounds C07D 207/16 (20130101) C07D 209/20 (20130101) C07D 209/24 (20130101) C07D 233/64 (20130101) C07D 241/08 (20130101) C07D 265/32 (20130101) C07D 403/06 (20130101) C07D 413/06 (20130101) C07D 487/04 (20130101) C07D 487/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) C12N 15/88 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/025 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/15 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11458163 | Forrest et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Kansas (Lawrence, Kansas); HylaPharm, LLC (Lawrence, Kansas) |
| ASSIGNEE(S) | University of Kansas (Lawrence, Kansas); HylaPharm, LLC (Lawrence, Kansas) |
| INVENTOR(S) | Laird Forrest (Lawrence, Kansas); Daniel Aires (Mission Hills, Kansas); Ryan Moulder (Lawrence, Kansas); Ruolin Lu (Lawrence, Kansas); Jordan Hunt (Lawrence, Kansas); Peter Kleindl (Lawrence, Kansas); Ti Zhang (Lawrence, Kansas); Chad Groer (Lawrence, Kansas); Shuang Cai (Lawrence, Kansas) |
| ABSTRACT | Provided are platinum(IV) compounds of Formula I or pharmaceutically acceptable salts thereof. Also provided are compositions including such compounds as well as methods of using the same. |
| FILED | Thursday, April 16, 2020 |
| APPL NO | 16/850748 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/243 (20190101) Original (OR) Class A61K 45/06 (20130101) A61K 47/36 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/0093 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11458168 | Metelitsa et al. |
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| FUNDED BY |
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| APPLICANT(S) | Baylor College of Medicine (Houston, Texas) |
| ASSIGNEE(S) | Baylor College of Medicine (Houston, Texas) |
| INVENTOR(S) | Leonid S. Metelitsa (Sugar Land, Texas); Amy N. Courtney (Houston, Texas); Gengwen Tian (Houston, Texas) |
| ABSTRACT | Embodiments of the disclosure include methods and compositions for producing NKT cells effective for immunotherapy and also methods and compositions for providing an effective amount of NKT cells to an individual in need of immunotherapy. In specific embodiments, the NKT cells are CD62L+ and have been exposed to one or more costimulatory agents to maintain CD62L expression. The NKT cells may be modified to incorporate a chimeric antigen receptor, in some cases. |
| FILED | Wednesday, May 23, 2018 |
| APPL NO | 15/987724 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/178 (20130101) A61K 39/0011 (20130101) A61K 2035/124 (20130101) A61K 2039/5156 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 37/00 (20180101) Peptides C07K 16/2803 (20130101) C07K 16/3084 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/10 (20130101) C12N 5/0646 (20130101) C12N 2501/599 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11458205 | Chilkoti et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Ashutosh Chilkoti (Durham, North Carolina); Samagya Banskota (Durham, North Carolina); Parisa Yousefpour (Durham, North Carolina); Jayanta Bhattacharyya (Durham, North Carolina) |
| ABSTRACT | Provided herein are conjugates including a polypeptide and one or more drug molecules. The polypeptide includes one or more charged motifs, and may further include one or more uncharged motifs. The conjugates may be used to effectively deliver the drug molecule to a subject. |
| FILED | Thursday, August 04, 2016 |
| APPL NO | 15/749797 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 38/00 (20130101) A61K 39/00 (20130101) A61K 39/395 (20130101) A61K 47/10 (20130101) A61K 47/60 (20170801) A61K 47/64 (20170801) Original (OR) Class A61K 2039/6031 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 7/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11458212 | Morse et al. |
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| FUNDED BY |
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| APPLICANT(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida); Arizona Board of Regents on Behalf of The University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida); Arizona Board of Regents on Behalf of the University of /Arizona (Tucson, Arizona) |
| INVENTOR(S) | David L. Morse (Tampa, Florida); Robert J. Gillies (Tampa, Florida); Amanda Huynh (Land O Lakes, Florida); Josef Vagner (Tucson, Arizona) |
| ABSTRACT | Cellular targets on cancer cells have been identified that can be used with targeted molecular imaging to detect the cancer cells in vivo. Non-invasive methods for detecting cancer cells, such as metastasized cancer cells, are therefore provided. Also provided are compositions and kits for use in the disclosed methods. |
| FILED | Monday, September 09, 2019 |
| APPL NO | 16/565188 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0021 (20130101) A61K 49/0056 (20130101) Original (OR) Class Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11458213 | Ray et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sangeeta Ray (Ellicott City, Maryland); Martin G. Pomper (Baltimore, Maryland) |
| ABSTRACT | Prostate-specific membrane antigen targeted high-affinity agents for endoradiotherapy of prostate cancer are disclosed. |
| FILED | Wednesday, March 22, 2017 |
| APPL NO | 16/087395 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/0482 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 257/02 (20130101) C07D 401/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11458221 | Kong et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Hyunjoon Kong (Champaign, Illinois); Yongbeom Seo (Woodbury, Minnesota); Jiayu Leong (Singapore, Singapore); Yu-Heng Deng (Urbana, Illinois) |
| ABSTRACT | Diatom microbubblers comprising diatom biosilica or other silica linked to a catalyst for the decomposition of hydrogen peroxide, such as manganese oxide (MnO2), platinum (Pt), CuO (copper II oxide), or zinc peroxide (ZnO2) particles or nanosheets, or catalase are provided. Further provided are methods of reducing or eliminating biofilm or biofouling conditions. |
| FILED | Wednesday, August 14, 2019 |
| APPL NO | 16/540291 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/26 (20130101) A61L 2/186 (20130101) Original (OR) Class Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/08 (20130101) B01J 23/34 (20130101) B01J 35/02 (20130101) B01J 35/0006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11458225 | Bharti et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Kapil Bharti (Potomac, Mississippi); Min Jae Song (Olney, Maryland); Russell Louis Quinn (Washington, District of Columbia) |
| ABSTRACT | Methods are disclosed for fabricating a three-dimensional engineered blood retinal barrier (BRB) comprising a choroid and retinal pigment epithelial cells. The methods include the use of bioprinting. Also disclosed is a three-dimensional engineered BRB, and its use. Methods are also disclosed for using the three-dimensional engineered BRB, such as for the treatment of retinal degeneration in a subject or screening. A three-dimensional printing insert that is adapted for bioprinting on a culture substrate sheet that is securely retained within and exposed through a printing frame is also disclosed. |
| FILED | Wednesday, November 08, 2017 |
| APPL NO | 16/347939 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/24 (20130101) A61L 27/52 (20130101) A61L 27/56 (20130101) A61L 27/58 (20130101) A61L 27/3808 (20130101) A61L 27/3813 (20130101) Original (OR) Class A61L 27/3891 (20130101) A61L 2430/16 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/069 (20130101) C12N 5/0621 (20130101) C12N 5/0656 (20130101) C12N 2500/38 (20130101) C12N 2501/11 (20130101) C12N 2501/17 (20130101) C12N 2501/39 (20130101) C12N 2501/90 (20130101) C12N 2501/105 (20130101) C12N 2501/115 (20130101) C12N 2501/165 (20130101) C12N 2533/40 (20130101) C12N 2533/50 (20130101) C12N 2533/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11458230 | Bettinger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Christopher J. Bettinger (Palo Alto, California); Joost P. Bruggeman (Schorl, Netherlands); Lino Da Silva Ferreira (Cambridge, Massachusetts); Jeffrey M. Karp (Chestnut Hill, Massachusetts); Robert S. Langer (Newton, Massachusetts); Christiaan Nijst (Amsterdam, Netherlands); Andreas Zumbuehl (Nyon, Switzerland); Jason Burdick (Philadelphia, Pennsylvania); Sonia J. Kim (West Nyack, New York) |
| ABSTRACT | The present inventions in various aspects provide elastic biodegradable polymers. In various embodiments, the polymers are formed by the reaction of a multifunctional alcohol or ether and a difunctional or higher order acid to form a pre-polymer, which is cross-linked to form the elastic biodegradable polymer. In preferred embodiments, the cross-linking is performed by functionalization of one or more OR groups on the pre-polymer backbone with vinyl, followed by photopolymerization to form the elastic biodegradable polymer composition or material. Preferably, acrylate is used to add one or more vinyls to the backbone of the pre-polymer to form an acrylated pre-polymer. In various embodiments, acrylated pre-polymers are co-polymerized with one or more acrylated co-polymers. |
| FILED | Friday, November 13, 2020 |
| APPL NO | 17/097901 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) A61K 35/48 (20130101) A61K 45/06 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/38 (20130101) A61L 27/58 (20130101) A61L 31/06 (20130101) Original (OR) Class A61L 31/148 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/6854 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/24 (20130101) C08J 3/246 (20130101) C08J 2367/00 (20130101) C08J 2367/07 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/0025 (20130101) C08K 5/0025 (20130101) Compositions of Macromolecular Compounds C08L 67/00 (20130101) C08L 67/07 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 11/087 (20200101) C12N 11/096 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11458337 | Ebbini et al. |
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| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | Emad S. Ebbini (Edina, Minnesota); Dalong Liu (Sammamish, Washington); Hasan Aldiabat (Minneapolis, Minnesota); Parker O'Brien (Minneapolis, Minnesota) |
| ABSTRACT | A dual-mode ultrasound system provides real-time imaging and therapy delivery using a transducer array. The system may use various imaging modes to provide image data that may be used to select control points within an imaging field of view. The control points along with the image data may be used to solve an optimization problem to achieve desired focusing gains at one or more of the control points. The optimized solution may be used to produce excitation waveforms to generate new image data. The focusing gains may be evaluated and the optimization problem may be iterated until desired focusing gains are achieved. Virtual arrays may be defined and cascaded to provide flexibility in solving the optimization problem. |
| FILED | Wednesday, November 28, 2018 |
| APPL NO | 16/202992 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/54 (20130101) A61B 8/145 (20130101) A61B 8/565 (20130101) A61B 8/0875 (20130101) A61B 8/4488 (20130101) A61B 8/5207 (20130101) A61B 2017/22008 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) Original (OR) Class A61N 7/02 (20130101) A61N 2007/0052 (20130101) A61N 2007/0078 (20130101) A61N 2007/0095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11458451 | Shaikh et al. |
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| FUNDED BY |
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| APPLICANT(S) | XPLOSAFE, LLC (Stillwater, Oklahoma) |
| ASSIGNEE(S) | XPLOSAFE, LLC (Stillwater, Oklahoma) |
| INVENTOR(S) | Shoaib F. Shaikh (Stillwater, Oklahoma); Allen W. Apblett (Stillwater, Oklahoma); Nicholas F. Materer (Stillwater, Oklahoma); Evgueni Kadossov (Stillwater, Oklahoma) |
| ABSTRACT | The present invention provides an improved sorbent and corresponding device(s) and uses thereof for the capture and stabilization of volatile organic compounds (VOC) or semi-volatile organic compounds (SVOC) from a gaseous atmosphere. The sorbent is capable of rapid and high uptake of one or more compounds and provides quantitative release (recovery) of the compound(s) when exposed to elevated temperature and/or organic solvent. Uses of particular improved grades of mesoporous silica are disclosed. |
| FILED | Tuesday, December 18, 2018 |
| APPL NO | 16/224049 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/02 (20130101) B01D 2253/106 (20130101) B01D 2257/708 (20130101) B01D 2259/4583 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/103 (20130101) Original (OR) Class B01J 20/3204 (20130101) B01J 20/3219 (20130101) B01J 20/3246 (20130101) B01J 20/3293 (20130101) B01J 20/28021 (20130101) B01J 20/28064 (20130101) B01J 20/28073 (20130101) B01J 20/28076 (20130101) B01J 20/28083 (20130101) Non-metallic Elements; Compounds Thereof; C01B 33/18 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/82 (20130101) C01P 2004/04 (20130101) C01P 2004/13 (20130101) C01P 2006/12 (20130101) C01P 2006/14 (20130101) C01P 2006/16 (20130101) Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 21/0091 (20130101) C06B 23/00 (20130101) C06B 45/00 (20130101) Blasting F42D 5/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459295 | Penning et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| INVENTOR(S) | Trevor M. Penning (Springfield, Pennsylvania); Adegoke Adeniji (Richmond Hill, Georgia); Lawrence J. Marnett (Nashville, Tennessee) |
| ABSTRACT | The invention includes 2-β-naphthyl-acetic acid derivatives, which are selective AKR1C3 inhibitors. In certain embodiments, the compounds of the invention are (R)-naproxen analogs. The invention further includes methods of treating cancer, such as prostate cancer and/or castration-resistant prostate cancer, using at least one compound of the invention. |
| FILED | Friday, October 21, 2016 |
| APPL NO | 15/769565 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/16 (20130101) A61K 31/52 (20130101) A61K 31/131 (20130101) A61K 31/192 (20130101) A61K 31/192 (20130101) A61K 31/337 (20130101) A61K 31/405 (20130101) A61K 31/506 (20130101) A61K 31/573 (20130101) A61K 31/4166 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 57/40 (20130101) C07C 59/64 (20130101) C07C 311/51 (20130101) Original (OR) Class C07C 317/44 (20130101) C07C 323/62 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459308 | Bowlin et al. |
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| FUNDED BY |
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| APPLICANT(S) | Microbiotix, Inc. (Worcester, Massachusetts); Albert Einstein College Of Medicine, Inc. (Bronx, New York); The Government Of The United States As Represented By The Secretary Of The Army (Fort Detrick, Maryland) |
| ASSIGNEE(S) | Microbiotix, Inc. (Worcester, Massachusetts); Albert Einstein College of Medicine (Bronx, New York); The Government of the United States as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Terry L. Bowlin (Maineville, Ohio); Donald T. Moir (Concord, Massachusetts); Kartik Chandran (Brooklyn, New York); John M. Dye, Jr. (Frederick, Maryland); John D. Williams (Fulton, Maryland); Zachary D. Aron (Acton, Massachusetts); Jay P. Barbor (Worcester, Massachusetts); Kelly N. Lively (Holliston, Massachusetts); Peter J. Nash (Newton, Massachusetts); Debra M. Mills (Francestown, New Hampshire); Arnab Basu (Acton, Massachusetts) |
| ABSTRACT | The present invention is related to the development of therapeutics and prophylactics for the treatment and/or prevention of filovirus infection in humans and other mammals. A new class of small molecules is disclosed that inhibits the interaction of naturally processed (i.e., proteolytically cleaved) filovirus glycoprotein (GPCL) with its host receptor Niemann-Pick C1 (NPC1) protein and thus block infection of host cells by filoviruses. Also disclosed are methods of using the small molecule inhibitors in the treatment/prevention of filovirus infection. |
| FILED | Tuesday, December 05, 2017 |
| APPL NO | 16/348033 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/00 (20130101) A61K 9/0014 (20130101) A61K 9/0029 (20130101) A61K 9/0053 (20130101) A61K 31/54 (20130101) A61K 31/437 (20130101) A61K 31/454 (20130101) A61K 31/496 (20130101) A61K 31/551 (20130101) A61K 31/4184 (20130101) A61K 31/4375 (20130101) A61K 31/5375 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Heterocyclic Compounds C07D 401/04 (20130101) Original (OR) Class C07D 401/14 (20130101) C07D 403/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459313 | Emadi et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Maryland, Baltimore (Baltimore, Maryland); MCDANIEL COLLEGE (Westminster, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland); MCDANIEL COLLEGE (Westminster, Maryland) |
| INVENTOR(S) | Ashkan Emadi (Clarksville, Maryland); Rena G. Lapidus (Baltimore, Maryland); Brandon A. Carter-Cooper (Manchester, Maryland); Steven Fletcher (Baltimore, Maryland); Dana Ferraris (Eldersburg, Maryland); Edward A. Sausville (Edgewater, Maryland) |
| ABSTRACT | The invention relates to new amino dimeric naphthoquinone compounds with antileukemic activity. Compounds of the invention demonstrated increased aqueous solubility compared to previously available dimeric naphthoquinones and potent nanomolar inhibition of cell survival in AML cells. Preferred compounds contained an aziridine or a secondary amino alcohol pharmacophore. |
| FILED | Thursday, October 05, 2017 |
| APPL NO | 16/344733 |
| ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) Acyclic or Carbocyclic Compounds C07C 225/30 (20130101) Heterocyclic Compounds C07D 203/14 (20130101) C07D 403/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459319 | Panicker |
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| FUNDED BY |
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| APPLICANT(S) | ANGION BIOMEDICA CORP. (Uniondale, New York) |
| ASSIGNEE(S) | Angion Biomedica Corp. (Uniondale, New York) |
| INVENTOR(S) | Bijoy Panicker (Holbrook, New York) |
| ABSTRACT | The present invention provides compounds having the general structural formula (I) (I) and pharmaceutically acceptable derivatives thereof, as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases involving fibrosis and proliferation, and where anti-fibrotic or anti-proliferative activity is beneficial. |
| FILED | Friday, September 25, 2020 |
| APPL NO | 17/032775 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/428 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/16 (20180101) A61P 3/10 (20180101) A61P 35/00 (20180101) Heterocyclic Compounds C07D 417/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459320 | Thompson et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| INVENTOR(S) | Scott Thompson (Baltimore, Maryland); Adam Van Dyke (Baltimore, Maryland); Craig Thomas (Gaithersburg, Maryland); Patrick Morris (Laurel, Maryland) |
| ABSTRACT | The present invention relates to novel alpha5 subunit-selective negative allosteric modulators of GABAA receptors that have been deuterated to improve their medicinal properties by prolonging their half-lives, rendering them useful as fast-acting pharmaceutical treatments for depression related disorders. |
| FILED | Tuesday, August 28, 2018 |
| APPL NO | 16/642445 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/19 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/24 (20180101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/05 (20130101) Heterocyclic Compounds C07D 261/08 (20130101) C07D 413/12 (20130101) C07D 417/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459321 | Remiszewski et al. |
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| FUNDED BY |
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| APPLICANT(S) | Evrys Bio, LLC (Doylestown, Pennsylvania) |
| ASSIGNEE(S) | Evrys Bio, LLC (Doylestown, Pennsylvania) |
| INVENTOR(S) | Stacy Remiszewski (Washington Township, New Jersey); Lillian W. Chiang (Princeton, New Jersey); Eain Anthony Murphy (Doylestown, Pennsylvania); Qun Sun (Princeton, New Jersey); Frank Kayser (San Francisco, California); Sarah Jocelyn Fink (Arlington, Massachusetts) |
| ABSTRACT | Novel thiazole- and isoquinoline-containing compounds are presented that are useful for treating and/or preventing broad-spectrum viral infections. Methods of treating and/or preventing broad-spectrum viral infections are also presented. These compounds have shown inhibition of HCMV, influenza viruses, Zika virus, BK Virus and RSV replication in cell-based assays. |
| FILED | Wednesday, October 17, 2018 |
| APPL NO | 16/756734 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Heterocyclic Compounds C07D 417/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459353 | Micalizio |
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| FUNDED BY |
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| APPLICANT(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | Glenn C. Micalizio (Hanover, New Hampshire) |
| ABSTRACT | Methods for producing enantiodefined polycyclic compounds, particularly tetracyclic compounds, are provided. More particularly, synthetic methods for producing biologically active enantiodefined steroidal compositions of both natural (“nat-”) and unnatural (“ent-”) absolute stereochemistry are provided. An exemplary method for manufacturing a tetracyclic compound comprises a step of forming a hydrindane intermediate through coupling of a suitably functionalized enyne with a suitably functionalized alkyne and subsequently performing an intramolecular ring-closing reaction to form the tetracyclic compound. Steroidal compounds obtained by this method and methods of using such steroidal compounds in human and/or animal therapeutics and medicines are also provided. |
| FILED | Thursday, August 16, 2018 |
| APPL NO | 16/637675 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Steroids C07J 11/00 (20130101) Original (OR) Class C07J 15/00 (20130101) C07J 75/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459360 | Kwong et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Peter Kwong (Washington, District of Columbia); Marie Pancera (Seattle, Washington); Tongqing Zhou (Boyds, Maryland); Ivelin Georgiev (Nashville, Tennessee); Michael Gordon Joyce (Washington, District of Columbia); Priyamvada Acharya (Fort Lee, New Jersey); Jason Gorman (Washington, District of Columbia); Yongping Yang (Potomac, Maryland); Guillaume Stewart-Jones (Bethesda, Maryland); Rita Chen (Bethesda, Maryland); Gwo-Yu Chuang (Rockville, Maryland); John Mascola (Rockville, Maryland); Baoshan Zhang (Bethesda, Maryland); Cheng Cheng (Bethesda, Maryland); Mallika Sastry (Rockville, Maryland); Aliaksandr Druz (Germantown, Maryland) |
| ABSTRACT | HIV-1 Env ectodomain trimers stabilized in a prefusion mature closed conformation and methods of their use and production are disclosed. In several embodiments, the HIV-1 Env ectodomain trimers and/or nucleic acid molecules can be used to generate an immune response to HIV-1 in a subject. In additional embodiments, the therapeutically effective amount of the HIV-1 Env ectodomain trimers can be administered to a subject in a method of treating or preventing HIV-1 infection. |
| FILED | Friday, August 30, 2019 |
| APPL NO | 16/557894 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) A61K 2039/55555 (20130101) A61K 2039/55561 (20130101) A61K 2039/55577 (20130101) Peptides C07K 14/005 (20130101) C07K 14/435 (20130101) Original (OR) Class C07K 16/1063 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16022 (20130101) C12N 2740/16034 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56988 (20130101) G01N 2333/162 (20130101) G01N 2469/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459378 | Caligiuri et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
| INVENTOR(S) | Michael Caligiuri (Columbus, Ohio); Jianhua Yu (Columbus, Ohio); Hongsheng Dai (Columbus, Ohio) |
| ABSTRACT | In certain embodiments, described herein is a method of treating a subject infected with a pathogen encoding an Fc-binding protein comprising administering to the subject a therapeutically effective amount of a pharmaceutical composition comprising an Fc region of an immunoglobulin G antibody. Also described herein is a method for treating cancer in a subject undergoing oncolytic viral therapy comprising administering to the subject a therapeutically effective amount of a pharmaceutical composition comprising an Fc region of an immunoglobulin G antibody. Further described herein is a method of activating natural killer (NK) cells in a subject infected with a pathogen, comprising administering to the subject a pharmaceutical composition comprising an Fc region of an immunoglobulin G antibody. |
| FILED | Tuesday, January 30, 2018 |
| APPL NO | 16/480293 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/08 (20130101) Peptides C07K 16/30 (20130101) C07K 16/087 (20130101) Original (OR) Class C07K 16/088 (20130101) C07K 2317/52 (20130101) C07K 2317/72 (20130101) C07K 2317/732 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0645 (20130101) C12N 2533/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459380 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (Waldorf, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Lai-Xi Wang (Ellicott City, Maryland); Xin Tong (College Park, Maryland); Tiezheng Li (Columbia, Maryland) |
| ABSTRACT | The present invention provides for a one-pot enzymatic approach which does not require removal of the enzyme and purification of the intermediate after deglycosylation step, and the Endo-S treatment is able to do both deglycosylation and transglycosylation. The one-pot strategy of the present invention enables chemoenzymatic synthesis of an azido-tagged N-glycoform of monocloncal antibodies which could be further modified through orthogonal chemical ligation for various applications. |
| FILED | Friday, June 29, 2018 |
| APPL NO | 16/022978 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 47/61 (20170801) A61K 47/549 (20170801) A61K 47/6803 (20170801) Peptides C07K 1/02 (20130101) C07K 1/36 (20130101) C07K 1/045 (20130101) C07K 1/1077 (20130101) C07K 16/18 (20130101) Original (OR) Class C07K 16/32 (20130101) C07K 16/2887 (20130101) C07K 2317/10 (20130101) C07K 2317/24 (20130101) C07K 2317/41 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/205 (20210501) C12N 9/2402 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/005 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/46 (20210501) Enzymes C12Y 302/01096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459381 | Claffey et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF CONNECTICUT (Farmington, Connecticut) |
| ASSIGNEE(S) | UNIVERSITY OF CONNECTICUT (Farmington, Connecticut) |
| INVENTOR(S) | Kevin P. Claffey (Burlington, Connecticut); Charan Devarakonda (Willimantic, Connecticut); Daniel Kita (Cheshire, Connecticut) |
| ABSTRACT | Described herein is an isolated antibody or antigen-binding fragment including a heavy chain variable region including three heavy chain complementary determining regions (HCDRs), wherein the sequence of HCDR1 is GYRLSELS (SEQ ID NO: 1), the sequence of HCDR2 is ISGWDGNT (SEQ ID NO: 2), and the sequence of HCDR3 is ARASGYNY (SEQ ID NO: 3), wherein the isolated antibody or antigen-binding fragment specifically binds human HSP90, specifically HSP90 beta. Also included are detection and therapeutic methods using the isolated antibodies or antigen-binding fragments. |
| FILED | Wednesday, August 07, 2019 |
| APPL NO | 16/533937 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/18 (20130101) Original (OR) Class C07K 16/28 (20130101) C07K 16/3015 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) C07K 2317/569 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57492 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459388 | Maute et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Roy Louis Maute (San Francisco, California); Kipp Andrew Weiskopf (Brookline, Massachusetts); Aaron Michael Ring (New Haven, Connecticut); Irving L. Weissman (Stanford, California) |
| ABSTRACT | Methods and compositions are provided for inducing phagocytosis of a target cell, treating an individual having cancer, treating an individual having an intracellular pathogen infection (e.g., a chronic infection), and/or reducing the number of inflicted cells (e.g., cancer cells, cells infected with an intracellular pathogen, etc.) in an individual. Methods and compositions are also provided for predicting whether an individual is resistant (or susceptible) to treatment with an anti-CD47/SIRPA agent. In some cases, the subject methods and compositions include an anti-MHC Class I/LILRB1 agent. In some cases, the subject methods and compositions include an anti-MHC Class I/LILRB1 agent and an anti-CD47/SIRPA agent (e.g., co-administration of an anti-MHC Class I/LILRB1 agent and an anti-CD47/SIRPA agent). Kits are also provided for practicing the methods of the disclosure. |
| FILED | Monday, December 14, 2020 |
| APPL NO | 17/121065 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/00491 (20130101) A61B 2017/00654 (20130101) A61B 2017/00893 (20130101) A61B 2017/00898 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/82 (20130101) A61F 2/945 (20130101) A61F 2002/041 (20130101) A61F 2002/044 (20130101) A61F 2002/045 (20130101) A61F 2002/048 (20130101) A61F 2002/823 (20130101) A61F 2210/0085 (20130101) A61F 2250/0067 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/1774 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/145 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/104 (20130101) A61M 2025/105 (20130101) Peptides C07K 16/2803 (20130101) C07K 16/2833 (20130101) Original (OR) Class C07K 16/2863 (20130101) C07K 2317/24 (20130101) C07K 2317/55 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459389 | Wittrup et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Karl Dane Wittrup (Boston, Massachusetts); Kai Wucherpfennig (Brookline, Massachusetts); Byong Ha Kang (Cambridge, Massachusetts); Nathan D. Mathewson (Boston, Massachusetts) |
| ABSTRACT | The present disclosure relates to, inter alia, compounds (e.g., antibodies, or antigen-binding fragments thereof) that bind to an epitope of CD161 an inhibit the interaction between CD161 and CLEC2D, and the use of the compounds in methods for treating, or ameliorating one or more symptoms of, cancer. |
| FILED | Monday, August 24, 2020 |
| APPL NO | 17/001031 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/2851 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/33 (20130101) C07K 2317/74 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459398 | Woods et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Elliot C. Woods (Burlingame, California); Han Xiao (East Palo Alto, California); Carolyn R. Bertozzi (Stanford, California); Melissa Gray (Stanford, California) |
| ABSTRACT | Provided are conjugates including a targeting moiety that binds to a cell surface molecule of a target cell and a target cell surface-editing enzyme. Also provided are compositions and kits that include the conjugates, as well as methods of using the conjugates. Methods of making conjugates are also provided. |
| FILED | Friday, June 30, 2017 |
| APPL NO | 16/308732 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/32 (20130101) Original (OR) Class C07K 19/00 (20130101) C07K 2317/732 (20130101) C07K 2319/33 (20130101) C07K 2319/035 (20130101) C07K 2319/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2402 (20130101) Enzymes C12Y 302/01018 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459400 | Koide et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Shohei Koide (Chicago, Illinois); Shun-Ichi Tanaka (Chicago, Illinois); Akiko Koide (Chicago, Illinois) |
| ABSTRACT | Aspects of the disclosure relate to compositions of enzyme-binding polypeptides (EBPs) that modify the substrate specificity of an enzyme and a method for identifying an EBP that modifies substrate specificity of an enzyme binding at least one substrate, the method comprising: contacting the enzyme with a polypeptide library comprising a plurality of EBPs that bind different epitopes of the enzyme; identifying EBPs that bind to the enzyme to form an EBP-enzyme complex; assaying for the activity level and substrate specificity of the EBP-enzyme complex; and identifying EBPs that modify the substrate specificity of the enzyme by identifying EBPs that, when in an EBP-enzyme complex, have a different substrate specificity than un-complexed EBP; wherein the catalytic rate constant of the EBP-enzyme complex is ≥50% of the un-complexed enzyme for at least one substrate and/or wherein the EBP-enzyme complex retains binding to a substrate. |
| FILED | Friday, July 15, 2016 |
| APPL NO | 15/745496 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/78 (20130101) C07K 16/40 (20130101) Original (OR) Class C07K 2317/70 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2318/20 (20130101) C07K 2319/00 (20130101) C07K 2319/01 (20130101) C07K 2319/20 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/20 (20130101) C12N 9/2471 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/00 (20130101) C12Q 1/25 (20130101) C12Q 1/26 (20130101) C12Q 1/34 (20130101) C12Q 1/48 (20130101) C12Q 1/527 (20130101) C12Q 1/533 (20130101) Enzymes C12Y 101/01001 (20130101) C12Y 301/01003 (20130101) C12Y 302/01023 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/60 (20130101) G01N 33/573 (20130101) G01N 33/582 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459439 | Nash et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California); The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California); The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | Landon D. Nash (Sunnyvale, California); Duncan J. Maitland (College Station, Texas); Nicole Docherty (Trop, Michigan); Thomas S. Wilson (San Leandro, California); Ward Small, IV (Livermore, California); Jason Ortega (Pacifica, California); Pooja Singhal (Redwood City, California) |
| ABSTRACT | An embodiment includes a system comprising: a monolithic shape memory polymer (SMP) foam having first and second states; wherein the SMP foam includes: (a) polyurethane, (b) an inner half portion having inner reticulated cells defined by inner struts, (c) an outer half portion, having outer reticulated cells defined by outer struts, surrounding the inner portion in a plane that provides a cross-section of the SMP foam, (d) hydroxyl groups chemically bound to outer surfaces of both the inner and outer struts. Other embodiments are discussed herein. |
| FILED | Tuesday, August 04, 2020 |
| APPL NO | 16/984370 |
| ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 24/0036 (20130101) A61L 24/046 (20130101) A61L 31/06 (20130101) A61L 31/06 (20130101) A61L 31/14 (20130101) A61L 31/146 (20130101) A61L 2400/16 (20130101) A61L 2430/36 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/62 (20130101) B05D 3/144 (20130101) B05D 7/02 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 44/5663 (20130101) B29C 59/14 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2033/04 (20130101) B29K 2069/00 (20130101) B29K 2075/00 (20130101) B29K 2077/00 (20130101) B29K 2995/0093 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/18 (20130101) B32B 27/06 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/36 (20130101) C08J 9/365 (20130101) Original (OR) Class C08J 2201/026 (20130101) C08J 2205/04 (20130101) C08J 2207/10 (20130101) C08J 2375/04 (20130101) Compositions of Macromolecular Compounds C08L 75/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459545 | Pelus et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Louis M. Pelus (Indianapolis, Indiana); Jonathan Hoggatt (Cambridge, Massachusetts) |
| ASSIGNEE(S) | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (Bloomington, Indiana) |
| INVENTOR(S) | Louis M. Pelus (Indianapolis, Indiana); Jonathan Hoggatt (Cambridge, Massachusetts) |
| ABSTRACT | The receptor EP4 is identified as the PGE2 receptor that is most responsible enhancing the homing and engraftment of hematopoietic stem and progenitor cells. Treatment of graft sources and graft recipients with compounds that preferentially target the EP4 receptor provide effective methods of increasing engraftment success while minimizing adverse side effects that may be associated with therapies that include the use of less selective molecules such as PGE2 and dmPGE2. One effective molecule used in such therapies is 5-[(1E,3R)-4,4-difluoro-3-hydroxy-4-phenyl-1-buten-1-yl]-1-[6-(2H-tetrazol-5R-yl)hexyl]-2-pyrrolidinone or a pharmaceutically acceptable salt thereof (L-902, 688). |
| FILED | Monday, November 15, 2010 |
| APPL NO | 13/509409 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0647 (20130101) Original (OR) Class C12N 2501/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459552 | Rajan |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| INVENTOR(S) | Rakhi Rajan (Norman, Oklahoma) |
| ABSTRACT | Bridge helix-modified variant Cas12a and Cas12b proteins having improved DNA cleavage selectivity in comparison to wild type versions of the Cas12a and Cas12b proteins, nucleic acids encoding the variant proteins, host cells containing the nucleic acids, and methods of their use. |
| FILED | Wednesday, July 01, 2020 |
| APPL NO | 16/946689 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 15/74 (20130101) C12N 15/113 (20130101) C12N 2310/20 (20170501) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459557 | Platt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Randall Jeffrey Platt (Basel, Switzerland); Feng Zhang (Cambridge, Massachusetts); Ian Slaymaker (Cambridge, Massachusetts) |
| ABSTRACT | Methods and compositions for inducing a plurality of mutations in transgenic Cas9 eukaryotes to model a neuronal disease or disorder. The invention further comprehends testing putative treatments with such models, e.g., testing putative chemical compounds that may be pharmaceutically relevant for treatment or gene therapy that may be relevant for treatment, or combinations thereof. The invention allows for the study of genetic diseases and putative treatments to better understand and alleviate a genetic disease or a condition, e.g., autism, autism-spectrum disease or disorder, obsessive-compulsive disorder, or psychiatric disorders. |
| FILED | Thursday, March 23, 2017 |
| APPL NO | 15/467949 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) A01K 2217/072 (20130101) A01K 2227/105 (20130101) A01K 2267/0306 (20130101) A01K 2267/0318 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/63 (20130101) C12N 15/86 (20130101) C12N 15/111 (20130101) C12N 15/907 (20130101) C12N 15/1024 (20130101) Original (OR) Class C12N 15/1082 (20130101) C12N 15/8509 (20130101) C12N 2015/8536 (20130101) C12N 2310/10 (20130101) C12N 2310/20 (20170501) C12N 2310/531 (20130101) C12N 2310/3519 (20130101) C12N 2320/11 (20130101) C12N 2320/32 (20130101) C12N 2330/51 (20130101) C12N 2740/16043 (20130101) C12N 2750/14143 (20130101) C12N 2830/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459558 | Nakai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Oregon Health and Science University (Portland, Oregon) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | Hiroyuki Nakai (Portland, Oregon); Samuel Huang (Portland, Oregon); Kei Adachi (Portland, Oregon) |
| ABSTRACT | Disclosed are methods for performing transcription-dependent directed evolution (TRADE) and novel AAV capsids selected using such methods. |
| FILED | Wednesday, June 02, 2021 |
| APPL NO | 17/337341 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/11 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 2310/11 (20130101) C12N 2320/33 (20130101) C12N 2750/14123 (20130101) C12N 2830/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459560 | Kogut et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado) |
| INVENTOR(S) | Igor Kogut (Aurora, Colorado); Dennis R. Roop (Greenwood Village, Colorado); Ganna Bilousova (Aurora, Colorado) |
| ABSTRACT | The present disclosure relates to methods and compositions for reprogramming cells to a pluripotent state. In particular, it relates to an integration- and feeder cell-free method for reprogramming primary human fibroblast cells to induced pluripotent stem cells (iPSCs). |
| FILED | Tuesday, November 22, 2016 |
| APPL NO | 16/072797 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 35/28 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0652 (20130101) C12N 5/0696 (20130101) C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 15/907 (20130101) C12N 2310/20 (20170501) C12N 2310/141 (20130101) C12N 2330/31 (20130101) C12N 2500/60 (20130101) C12N 2501/65 (20130101) C12N 2501/115 (20130101) C12N 2501/602 (20130101) C12N 2501/603 (20130101) C12N 2501/604 (20130101) C12N 2501/605 (20130101) C12N 2501/606 (20130101) C12N 2501/608 (20130101) C12N 2506/1307 (20130101) C12N 2510/00 (20130101) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459562 | Zamore et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| ASSIGNEE(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| INVENTOR(S) | Phillip D. Zamore (Northboro, Massachusetts); Guiliang Tang (Worcester, Massachusetts) |
| ABSTRACT | Based at least in part on an understanding of the mechanisms by which small RNAs (e.g., naturally-occurring miRNAs) mediate RNA silencing in plants, rules have been established for determining, for example, the degree of complementarity required between an RNAi-mediating agent and its target, i.e., whether mismatches are tolerated, the number of mismatches tolerated, the effect of the position of the mismatches, etc. Such rules are useful, in particular, in the design of improved RNAi-mediating agents which allow for more exact control of the efficacy of RNA silencing. |
| FILED | Thursday, June 13, 2019 |
| APPL NO | 16/440722 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 15/8218 (20130101) C12N 15/8261 (20130101) C12N 2310/14 (20130101) C12N 2310/335 (20130101) C12N 2320/50 (20130101) Technologies for Adaptation to Climate Change Y02A 40/146 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459564 | Rigo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | IONIS PHARMACEUTICALS, INC. (Carlsbad, California); BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | IONIS PHARMACEUTICALS, INC. (Carlsbad, California); THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Frank Rigo (Carlsbad, California); Thazha P. Prakash (Carlsbad, California); David Corey (Dallas, Texas) |
| ABSTRACT | Certain embodiments are directed to methods and compounds for increasing FXN. Such methods and compounds are useful for increasing expression of FXN in cells and animals. |
| FILED | Friday, December 21, 2018 |
| APPL NO | 16/956425 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/322 (20130101) C12N 2310/3231 (20130101) C12N 2310/3233 (20130101) C12N 2310/3341 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459565 | Martin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Baylor College of Medicine (Houston, Texas); Texas Heart Institute (Houston, Texas) |
| ASSIGNEE(S) | BAYLOR COLLEGE OF MEDICINE (Houston, Texas) |
| INVENTOR(S) | James F. Martin (Pearland, Texas); Yuka Morikawa (Houston, Texas); Todd Ryan Heallen (Houston, Texas); John Leach (Houston, Texas) |
| ABSTRACT | Embodiments of the disclosure include methods and compositions for the renewal of cardiomyocytes by targeting the Hippo pathway. In particular embodiments, an individual with a need for cardiomyocyte renewal is provided an effective amount of a shRNA molecule that targets the Sav1 gene. Particular shRNA sequences are disclosed. |
| FILED | Thursday, November 12, 2020 |
| APPL NO | 17/096260 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/531 (20130101) C12N 2320/30 (20130101) C12N 2740/15043 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459568 | Messina et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Louis M. Messina (Westborough, Massachusetts); Guodong Tie (Shrewsbury, Massachusetts) |
| ABSTRACT | Methods and compositions for treating cancer, e.g., colorectal cancer, using a miR-101-3p inhibitor. |
| FILED | Tuesday, October 31, 2017 |
| APPL NO | 16/332588 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1135 (20130101) C12N 15/1137 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/141 (20130101) C12N 2310/531 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459570 | Albers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Mark William Albers (Winchester, Massachusetts); Steven Rodriguez (Chelsea, Massachusetts) |
| ABSTRACT | Methods for treating, and for identifying novel treatments for, neurodegenerative diseases, as well as animal and cellular models. |
| FILED | Friday, June 14, 2019 |
| APPL NO | 16/442143 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) A01K 2207/15 (20130101) A01K 2217/052 (20130101) A01K 2227/105 (20130101) A01K 2267/0312 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 39/39541 (20130101) A61K 48/0016 (20130101) Peptides C07K 14/4711 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/117 (20130101) Original (OR) Class C12N 2310/17 (20130101) C12N 2310/53 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459586 | Church et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | George M. Church (Brookline, Massachusetts); Susan M. Byrne (Brookline, Massachusetts) |
| ABSTRACT | Inhibiting p53 or Bax can be used to improve nuclease-mediated gene targeting frequencies in stem cells. This inhibition can be achieved, e.g., by overexpression of anti-apoptosis proteins or by silencing or reducing p53 or Bax expression. This technique can be used in conjunction with other rapidly developing CRISPR technologies, including improvements in specificity, other types of nucleases, and further enrichment, screening, and selection schemes, to expand the use of stem cells in experimental studies and tissue engineering for therapeutic purposes. |
| FILED | Wednesday, April 19, 2017 |
| APPL NO | 16/094011 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0606 (20130101) C12N 5/0619 (20130101) C12N 5/0663 (20130101) C12N 5/0696 (20130101) C12N 9/22 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2740/16043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459599 | Doudna et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jennifer A. Doudna (Berkeley, California); Mitchell Ray O'Connell (Oakland, California); Alexandra East-Seletsky (San Francisco, California); Spencer Charles Knight (Berkeley, California); James Harrison Doudna Cate (Berkeley, California) |
| ABSTRACT | The present disclosure provides methods for detecting a single-stranded target RNA. The present disclosure provides methods of cleaving a precursor C2c2 guide RNA array into two or more C2c2 guide RNAs. The present disclosure provides a kit for detecting a target RNA in a sample. |
| FILED | Friday, September 20, 2019 |
| APPL NO | 16/577696 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6823 (20130101) Original (OR) Class C12Q 1/6823 (20130101) C12Q 2521/327 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459600 | Doudna et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jennifer A. Doudna (Berkeley, California); Mitchell Ray O'Connell (Oakland, California); Alexandra East-Seletsky (San Francisco, California); Spencer Charles Knight (Berkeley, California); James Harrison Doudna Cate (Berkeley, California) |
| ABSTRACT | The present disclosure provides methods for detecting a single-stranded target RNA. The present disclosure provides methods of cleaving a precursor C2c2 guide RNA array into two or more C2c2 guide RNAs. The present disclosure provides a kit for detecting a target RNA in a sample. |
| FILED | Friday, September 20, 2019 |
| APPL NO | 16/577740 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6823 (20130101) Original (OR) Class C12Q 1/6823 (20130101) C12Q 2521/327 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459611 | Vogelstein et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Nickolas Papadopoulos (Towson, Maryland); Isaac A. Kinde (Beaumont, California) |
| ABSTRACT | The identification of mutations that are present in a small fraction of DNA templates is essential for progress in several areas of biomedical research. Though massively parallel sequencing instruments are in principle well-suited to this task, the error rates in such instruments are generally too high to allow confident identification of rare variants. We here describe an approach that can substantially increase the sensitivity of massively parallel sequencing instruments for this purpose. One example of this approach, called “Safe-SeqS” for (Safe-Sequencing System) includes (i) assignment of a unique identifier (UID) to each template molecule; (ii) amplification of each uniquely tagged template molecule to create UID-families; and (iii) redundant sequencing of the amplification products. PCR fragments with the same UID are truly mutant (“super-mutants”) if ≥95% of them contain the identical mutation. We illustrate the utility of this approach for determining the fidelity of a polymerase, the accuracy of oligonucleotides synthesized in vitro, and the prevalence of mutations in the nuclear and mitochondrial genomes of normal cells. |
| FILED | Tuesday, May 21, 2019 |
| APPL NO | 16/417817 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 1/6874 (20130101) C12Q 1/6876 (20130101) C12Q 2525/179 (20130101) C12Q 2525/191 (20130101) C12Q 2535/122 (20130101) C12Q 2563/179 (20130101) C12Q 2565/514 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459613 | Ebert et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Benjamin Levine Ebert (Boston, Massachusetts); Quinlan Sievers (Boston, Massachusetts) |
| ABSTRACT | In one aspect, the present invention features method of identifying a cell resistant to a modulator of Cereblon (CRBN). In another aspect, the present invention features a method of characterizing sensitivity of a subject to a modulator of CRBN. In yet another aspect, the present invention features a method of monitoring sensitivity of a subject to a modulator of CRBN. |
| FILED | Friday, September 09, 2016 |
| APPL NO | 15/759159 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/45 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6881 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459617 | Symmans et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas); Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas); Yale University (New Haven, Connecticut) |
| INVENTOR(S) | William Fraser Symmans (Houston, Texas); Bruno Sinn (Berlin, Germany); Christos Hatzis (Guilford, Connecticut); Chunxiao Fu (Pearland, Texas); Rosanna Lau (Houston, Texas) |
| ABSTRACT | Provided herein are methods of determining tumoral sensitivity to hormonal (endocrine) therapy based upon an index of estrogen receptor (ER)- and progesterone receptor (PR)-related genes, referred to as the sensitivity to endocrine therapy index (SETER/PR index), and may have additional consideration for the proportion of ER gene (ESRI) RNA transcripts that contain a mutation relative to the value of the SETER/PR index. Further provided are methods of treating breast cancer patients determined to be sensitive to an endocrine therapy by the SETER/PR index. |
| FILED | Friday, April 28, 2017 |
| APPL NO | 16/097102 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/138 (20130101) A61K 31/566 (20130101) A61K 31/4196 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/10 (20190201) G16B 25/20 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459624 | Petropoulos |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MONOGRAM BIOSCIENCES, INC. (South San Francisco, California) |
| ASSIGNEE(S) | Monogram Biosciences, Inc. (South San Francisco, California) |
| INVENTOR(S) | Christos J. Petropoulos (Half Moon Bay, California) |
| ABSTRACT | The invention provides a method for determining whether a human immunodeficiency virus is resistant to a viral entry inhibitor. The methods are particularly useful for determining resistance to inhibitors that act by a non-competitive mechanism. In certain aspects, the methods comprise determining whether an HIV population is resistant to an HIV entry inhibitor, comprising determining a log-sigmoid inhibition curve comprising data points for entry of the HIV population in the presence of varying concentrations of the HIV entry inhibitor, wherein if the entry of the HIV population cannot be completely inhibited by the HIV entry inhibitor, the HIV population is resistant to the HIV entry inhibitor. |
| FILED | Monday, February 03, 2020 |
| APPL NO | 16/780426 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/16021 (20130101) C12N 2740/16062 (20130101) C12N 2740/16122 (20130101) C12N 2770/20021 (20130101) C12N 2800/40 (20130101) C12N 2800/107 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/04 (20130101) C12Q 1/66 (20130101) C12Q 1/70 (20130101) C12Q 1/703 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101) G01N 2333/16 (20130101) G01N 2333/162 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11460383 | Rozhok et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NanoCytomics, LLC (Evanston, Illinois); NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | NanoCytomics, LLC (Evanston, Illinois); Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Sergey Rozhok (Evanston, Illinois); Justin R. Derbas (Evanston, Illinois); Jarema Czarnecki (Evanston, Illinois); Hariharan Subramanian (Evanston, Illinois) |
| ABSTRACT | Automated cell staining systems and methods are disclosed herein. In particular, the staining systems disclosed herein provide low-volume, automated bench top staining systems for staining biological samples contained on a cytological slide. |
| FILED | Friday, June 16, 2017 |
| APPL NO | 16/310130 |
| ART UNIT | 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Apparatus for Applying Fluent Materials to Surfaces, in General B05C 3/02 (20130101) B05C 3/08 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/28 (20130101) G01N 1/30 (20130101) G01N 1/312 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11460395 | Ozcan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Aydogan Ozcan (Los Angeles, California); Aniruddha Ray (Toledo, Ohio); Hyouarm Joung (Los Angeles, California); Derek Tseng (Buena Park, California); Isidro B. Salusky (Los Angeles, California) |
| ABSTRACT | A portable colorimetric assay system includes an opto-mechanical reader configured to be detachably mounted to a mobile phone having a camera or other camera-containing portable electronic device. The opto-mechanical reader includes one or more light sources configured to illuminate a test sample holder and control sample holder disposed in the opto-mechanical reader along an optical path aligned with a camera of the mobile phone or other camera-containing portable electronic device. One or more serum separation membranes are disposed in the opto-mechanical reader and define a sample receiving pad configured to receive a blood sample. A moveable serum collection membrane is membrane is also disposed in the reader and is configured to contact the sample receiving pad in a first position and moveable to a second position where the serum collection membrane is disposed inside the test sample holder. |
| FILED | Friday, June 12, 2020 |
| APPL NO | 16/900838 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5023 (20130101) B01L 3/502753 (20130101) B01L 2300/0681 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/01 (20130101) Original (OR) Class G01N 21/78 (20130101) G01N 21/251 (20130101) G01N 21/8483 (20130101) G01N 33/49 (20130101) G01N 2021/0137 (20130101) G01N 2021/1776 (20130101) G01N 2201/104 (20130101) G01N 2201/0221 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11460435 | Barrall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ELECTRONIC BIOSCIENCES, INC. (San Diego, California) |
| ASSIGNEE(S) | ELECTRONIC BIOSCIENCES, INC. (San Diego, California) |
| INVENTOR(S) | Geoffrey A. Barrall (San Jose, California); Eric N. Ervin (Holladay, Utah); Prithwish Pal (San Diego, California) |
| ABSTRACT | Provided are device components, devices and methods characterized by a high contrast signal to noise ratio (CNR). |
| FILED | Wednesday, January 16, 2019 |
| APPL NO | 16/249312 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/447 (20130101) Original (OR) Class G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11460685 | Hillman |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trusteees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Elizabeth M. C. Hillman (New York, New York) |
| ABSTRACT | Methods, devices and systems for up to three-dimensional scanning of target regions at high magnification are disclosed. |
| FILED | Wednesday, September 30, 2020 |
| APPL NO | 17/038902 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/0032 (20130101) G02B 21/0052 (20130101) G02B 21/361 (20130101) G02B 21/367 (20130101) Original (OR) Class G02B 23/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11461496 | Norgeot et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Beau Norgeot (Palo Alto, California); Atul Butte (San Francisco, California); Gundolf Schenk (San Francisco, California); Eugenia Rutenberg (San Francisco, California) |
| ABSTRACT | A system is provided for de-identifying electronic records. The system may be configured to tokenize an electronic record to produce a plurality of tokens including a first token. The system may determine whether the first token is part of one of a plurality of expressions known to include protected health information. In response to determining that the first token is not part of any one of the plurality of expressions, the system may determine, based on a blacklist of tokens known to include protected health information, whether the first token includes protected health information. In response to determining that the first token includes protected health information, the system may generate a de-identified electronic record by replacing the first token with a second token obfuscating the protected health information. Related methods and computer program products are also provided. |
| FILED | Tuesday, June 09, 2020 |
| APPL NO | 16/897153 |
| ART UNIT | 2493 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/33 (20130101) G06F 21/6254 (20130101) Original (OR) Class G06F 40/284 (20200101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11461618 | Sussillo et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | David Sussillo (Portola Valley, California); Jonathan C. Kao (Stanford, California); Sergey Stavisky (San Francisco, California); Krishna V. Shenoy (Palo Alto, California) |
| ABSTRACT | A brain machine interface (BMI) to control a device is provided. The BMI has a neural decoder, which is a neural to kinematic mapping function with neural signals as input to the neural decoder and kinematics to control the device as output of the neural decoder. The neural decoder is based on a continuous-time multiplicative recurrent neural network, which has been trained as a neural to kinematic mapping function. An advantage of the invention is the robustness of the decoder to perturbations in the neural data; its performance degrades less—or not at all in some circumstances—in comparison to the current state decoders. These perturbations make the current use of BMI in a clinical setting extremely challenging. This invention helps to ameliorate this problem. The robustness of the neural decoder does not come at the cost of some performance, in fact an improvement in performance is observed. |
| FILED | Monday, March 04, 2019 |
| APPL NO | 16/292000 |
| ART UNIT | 2127 — AI & Simulation/Modeling |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/24 (20210101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) G06N 3/0445 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11461891 | Madabhushi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Cristian Barrera (Bogota, Colombia); German Corredor (Bogota, Colombia); Eduardo Romero (Bogota, Colombia) |
| ABSTRACT | Embodiments include controlling a processor to access an image of a region of tissue demonstrating cancerous pathology; segment a cellular nucleus represented in the image; extract a first set of features from the segmented cellular nucleus; classify the segmented nucleus as a lymphocyte or non-lymphocyte based on the first set of features; for a segmented nucleus classified as a lymphocyte: computing a set of contextual features; assign the segmented nucleus classified as a lymphocyte to one of a plurality of clusters based on the set of contextual features; compute a frequency distribution of the clustered segmented nuclei classified as lymphocytes; provide the frequency distribution to a machine learning classifier; receive, from the machine learning classifier, a classification of the region of tissue as likely to experience recurrence or unlikely to experience recurrence, based, at least in part, on the frequency distribution; and display the classification. |
| FILED | Thursday, January 31, 2019 |
| APPL NO | 16/263334 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6228 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 2207/10056 (20130101) G06T 2207/20081 (20130101) G06T 2207/30024 (20130101) G06T 2207/30061 (20130101) G06T 2207/30096 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 40/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11457625 | Stote |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Natick, Massachusetts) |
| ASSIGNEE(S) | U.S. Government as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Robert E Stote (Pepperell, Massachusetts) |
| ABSTRACT | The disclosed subject matter relates to a textile or fabric and methods of making them that includes a composition that selectively binds odor causing and/or pathogenic bacteria, but avoids binding beneficial bacteria and an antimicrobial composition that kills the selectively bound odor causing and/or pathogenic bacteria. The composition that selectively binds odor causing and/or pathogenic bacteria can be a peptide. |
| FILED | Thursday, October 10, 2019 |
| APPL NO | 16/597886 |
| ART UNIT | 1699 — SELECT * FROM codes_techcenter; |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/34 (20130101) Original (OR) Class A01N 47/40 (20130101) Peptides C07K 7/08 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 16/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11457815 | Won |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Temple University Of The Commonwealth System Of Higher Education (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Chang-Hee Won (Maple Glen, Pennsylvania) |
| ABSTRACT | A mobile-platform imaging device uses compression of the target region to generate an image of an object. A tactile sensor has an optical waveguide with a flexible, transparent first layer. Light is directed into the waveguide. Light is scattered out of the first layer when the first layer is deformed. The first layer is deformed by the tactile sensor being pressed against the object, A force sensor detects a force pressing the tactile sensor against the object and outputs corresponding force information. A first communication unit receives the force information from the force sensor. A receptacle holds a mobile device with a second communication unit and an imager that can generate image information using light scattered out of the first layer. The first communication unit communicates with the second communication unit and the mobile device communicates with an external network. |
| FILED | Thursday, July 26, 2018 |
| APPL NO | 16/634445 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0022 (20130101) A61B 5/0053 (20130101) Original (OR) Class A61B 5/0059 (20130101) A61B 5/444 (20130101) A61B 5/6843 (20130101) A61B 5/6898 (20130101) A61B 5/7267 (20130101) A61B 5/7275 (20130101) A61B 2090/306 (20160201) A61B 2562/0238 (20130101) A61B 2576/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/08 (20130101) G01N 19/00 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/30096 (20130101) Telephonic Communication H04M 1/04 (20130101) H04M 2250/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11457845 | Izzetoglu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Meltem Izzetoglu (Bryn Mawr, Pennsylvania); Juan Du (Broomall, Pennsylvania); Baruch Ben Dor (Radnor, Pennsylvania); Shadi Malaeb (Ardmore, Pennsylvania) |
| ABSTRACT | A system, device and methods for quantitatively monitoring and evaluating changes in water and hemoglobin content in the brain in a non-invasive manner are provided. The system may be used for real-time detection and monitoring of brain edema and/or for an assessment of cerebral autoregulation. |
| FILED | Wednesday, October 23, 2019 |
| APPL NO | 16/661352 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/0075 (20130101) A61B 5/4064 (20130101) A61B 5/4878 (20130101) A61B 5/6814 (20130101) A61B 5/6833 (20130101) A61B 5/14552 (20130101) A61B 5/14553 (20130101) Original (OR) Class A61B 2562/166 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11458042 | Magin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida); SHARKLET TECHNOLOGIES, INC. (Aurora, Colorado) |
| ASSIGNEE(S) | SHARKLET TECHNOLOGIES, INC. (Aurora, Colorado); UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
| INVENTOR(S) | Chelsea Marie Magin (Boulder, Colorado); Anthony B. Brennan (Gainesville, Florida); Bradley Jay Willenberg (Orlando, Florida); Gregory Scott Schultz (Gainesville, Florida); Dylan Burton Neale (Gainesville, Florida) |
| ABSTRACT | Disclosed herein is a multilayered wound dressing comprising a first layer; the first layer including channels that facilitate neovascularization of a wound; and a second layer in contact with the first layer, the second layer having the same or different chemical composition as the first layer; where the second layer comprises at least one surface that has a texture and the direction of the texture is operative to facilitate cell orientation and growth. A method includes forming a first layer of a polymeric material; forming a second layer of the same polymeric material as the first layer on the first layer; and forming a textured surface of the second layer of the same polymeric material as the first layer, the textured surface being operative to facilitate directional cell growth when used in a wound dressing, where the first layer and the second layer are formed using an additive manufacturing process. |
| FILED | Monday, April 25, 2016 |
| APPL NO | 15/568767 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 13/022 (20130101) A61F 13/00029 (20130101) A61F 13/00063 (20130101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/42 (20130101) A61L 15/60 (20130101) A61L 15/64 (20130101) A61L 15/425 (20130101) A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/50 (20130101) A61L 27/58 (20130101) A61L 27/60 (20130101) A61L 2300/414 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11458064 | Asbeck et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Alan Thomas Asbeck (Waltham, Massachusetts); Ye Ding (Cambridge, Massachusetts); Ignacio Galiana Bujanda (Cambridge, Massachusetts); Sangjun Lee (Cambridge, Massachusetts); Diana Wagner (Charlotte, North Carolina); Conor J. Walsh (Cambridge, Massachusetts) |
| ABSTRACT | Systems and methods for providing assistance with human motion, including hip and ankle motion, are disclosed. Sensor feedback is used to determine an appropriate profile for actuating a wearable robotic system to deliver desired joint motion assistance. Variations in user kinetics and kinematics, as well as construction, materials, and fit of the wearable robotic system, are considered in order to provide assistance tailored to the user and current activity. |
| FILED | Monday, August 12, 2019 |
| APPL NO | 16/538746 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 5/01 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/0262 (20130101) A61H 1/0266 (20130101) A61H 3/00 (20130101) Original (OR) Class A61H 2003/007 (20130101) A61H 2201/165 (20130101) A61H 2201/501 (20130101) A61H 2201/503 (20130101) A61H 2201/1659 (20130101) A61H 2201/1695 (20130101) A61H 2201/5038 (20130101) A61H 2201/5061 (20130101) A61H 2201/5069 (20130101) A61H 2201/5071 (20130101) A61H 2201/5079 (20130101) A61H 2201/5084 (20130101) A61H 2201/5097 (20130101) A61H 2205/106 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11458210 | Ruoslahti et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California) |
| ASSIGNEE(S) | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE (La Jolla, California) |
| INVENTOR(S) | Erkki Ruoslahti (La Jolla, California); Aman Mann (La Jolla, California); Pablo Scodeller (La Jolla, California); Sazid Hussain (La Jolla, California) |
| ABSTRACT | Compositions are disclosed which include a CAQK peptide linked or conjugated to a cargo composition, where the peptide selectively homes the composition to a site of nervous system injury in a subject. |
| FILED | Monday, April 27, 2020 |
| APPL NO | 16/859893 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/5115 (20130101) A61K 47/62 (20170801) A61K 47/6425 (20170801) A61K 47/6923 (20170801) A61K 47/6929 (20170801) Original (OR) Class A61K 48/005 (20130101) A61K 48/0008 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 43/00 (20180101) Peptides C07K 5/1013 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11458216 | Ehrensberger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Buffalo, New York); Syracuse University (Syracuse, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Amherst, New York); Syracuse University (Syracuse, New York) |
| INVENTOR(S) | Mark Ehrensberger (Amherst, New York); Anthony A. Campagnari (Hamburg, New York); Esther Takeuchi (South Setauket, New York); Nicole Luke-Marshall (Webster, New York); Jeremy Gilbert (Charleston, South Carolina); Edward P. Furlani (Lancaster, New York); Albert H. Titus (Buffalo, New York); Amir Mokhtare (Amherst, New York) |
| ABSTRACT | The disclosure describes a method of reducing or preventing the growth of microbes on the surface of an object, wherein the object is of such material that it can act as a working electrode. The method comprises the steps of providing a counter electrode, and a reference electrode. The object is used as the working electrode. A first electrical current is passed through the working and counter electrodes. The first current through the counter electrode is varied such that a first electric potential of the working electrode is constant relative to the electric potential of the reference electrode. In some embodiments, a second electrical current is passed through the counter electrode such that a second electric potential of the working electrode is constant relative to the electric potential of the reference electrode. |
| FILED | Wednesday, April 04, 2018 |
| APPL NO | 15/945727 |
| ART UNIT | 1799 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/30 (20130101) A61F 2/482 (20210801) A61F 2002/30677 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/03 (20130101) Original (OR) Class A61L 2/24 (20130101) A61L 2202/14 (20130101) A61L 2202/21 (20130101) A61L 2202/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11458451 | Shaikh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | XPLOSAFE, LLC (Stillwater, Oklahoma) |
| ASSIGNEE(S) | XPLOSAFE, LLC (Stillwater, Oklahoma) |
| INVENTOR(S) | Shoaib F. Shaikh (Stillwater, Oklahoma); Allen W. Apblett (Stillwater, Oklahoma); Nicholas F. Materer (Stillwater, Oklahoma); Evgueni Kadossov (Stillwater, Oklahoma) |
| ABSTRACT | The present invention provides an improved sorbent and corresponding device(s) and uses thereof for the capture and stabilization of volatile organic compounds (VOC) or semi-volatile organic compounds (SVOC) from a gaseous atmosphere. The sorbent is capable of rapid and high uptake of one or more compounds and provides quantitative release (recovery) of the compound(s) when exposed to elevated temperature and/or organic solvent. Uses of particular improved grades of mesoporous silica are disclosed. |
| FILED | Tuesday, December 18, 2018 |
| APPL NO | 16/224049 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/02 (20130101) B01D 2253/106 (20130101) B01D 2257/708 (20130101) B01D 2259/4583 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/103 (20130101) Original (OR) Class B01J 20/3204 (20130101) B01J 20/3219 (20130101) B01J 20/3246 (20130101) B01J 20/3293 (20130101) B01J 20/28021 (20130101) B01J 20/28064 (20130101) B01J 20/28073 (20130101) B01J 20/28076 (20130101) B01J 20/28083 (20130101) Non-metallic Elements; Compounds Thereof; C01B 33/18 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/82 (20130101) C01P 2004/04 (20130101) C01P 2004/13 (20130101) C01P 2006/12 (20130101) C01P 2006/14 (20130101) C01P 2006/16 (20130101) Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 21/0091 (20130101) C06B 23/00 (20130101) C06B 45/00 (20130101) Blasting F42D 5/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459094 | Di Leo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Claudio V. Di Leo (Atlanta, Georgia); Mark F. Costello (Atlanta, Georgia); Benjamin Leon (Atlanta, Georgia); Julian Jose Rimoli (Atlanta, Georgia); Michael B. Ward (Atlanta, Georgia) |
| ABSTRACT | A leg mechanism includes an articulated leg system (100), a passive device (130) and a cable (134). The articulated leg system (100) has a leg portion (128). The passive device (130) is coupled to the articulated leg system and is configured to apply a first force to a portion thereof. The cable (134) is coupled to the articulated leg system (100) and is configured to apply a second force, in opposition to the first force, to a portion thereof. When the cable (134) is drawn away from the articulated leg system (100), the second force moves the leg portion (128) in a first direction. When tension is released from the cable (134), the passive device (130) exerts the first force so as to move the leg portion (128) a second direction that is opposite the first direction. |
| FILED | Friday, September 28, 2018 |
| APPL NO | 16/645370 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 25/001 (20130101) B64C 25/12 (20130101) B64C 25/20 (20130101) Original (OR) Class B64C 25/62 (20130101) B64C 2025/008 (20130101) B64C 2025/125 (20130101) B64C 2025/325 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459133 | Jaeger |
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| FUNDED BY |
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| APPLICANT(S) | NOVAWURKS, INC. (Los Alamitos, California) |
| ASSIGNEE(S) | NOVAWURKS, INC. (Los Alamitos, California) |
| INVENTOR(S) | Talbot Jaeger (Los Alamitos, California) |
| ABSTRACT | A method is provided for realigning or relieving mechanical stress in a spacecraft frame. The process includes providing a spacecraft which includes at least two frame subsections connected by a mechanical connector. The mechanical connector provides both a soft dock connection which mechanically connects the two frame subsections but allows relative movement between the two frame sections and a hard dock connection which mechanically connects the two frame subsections but does not allow relative movement between the two frame sections. Once in space, a controller causes the mechanical connector to transition from a hard dock connection to a soft dock connection, which is maintained for a predetermined time period to realign or relieve stress within the spacecraft frame. Thereafter, the controller causes the mechanical connector to transition from the soft dock connection back to the hard dock connection. |
| FILED | Wednesday, May 08, 2019 |
| APPL NO | 16/406932 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/646 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459231 | Blankenship |
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| FUNDED BY |
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| APPLICANT(S) | UNITED STATES GOVERNMENT AS REPRESENTED BY THE SECRETARY OF THE ARMY (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Government as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Clinton Blankenship (Redstone Arsenal, Alabama) |
| ABSTRACT | The present disclosure provides a microelectronic isolation system comprising a base, vibration isolator, primary sensor, and microprocessor. The base supports the vibration isolator, the primary sensor, and the microprocessor. The vibration isolator has a platform, isolation material, and at least one isolation sensor. The isolation material dampens an overall vibrational frequency experienced by the microelectronic isolation system. The isolation sensor measures a displacement. The displacement is a measurement of a displacement of the platform with respect to the base. The primary sensor measures a primary sensor response, which is received by the microprocessor to calculate a plurality of responses. The plurality of responses of the microprocessor being one or a combination of a measured compensation response, an inertial response, and a restored primary sensor response. |
| FILED | Monday, November 23, 2020 |
| APPL NO | 17/101732 |
| ART UNIT | 2898 — Semiconductors/Memory |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 7/0058 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459304 | Miao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Lei Miao (San Jose, California); Linxian Li (Malden, Massachusetts); Daniel Griffith Anderson (Framingham, Massachusetts); Yuxuan Huang (Cambridge, United Kingdom) |
| ABSTRACT | Provided herein are lipidoid compounds of Formulae (I) and (II), and pharmaceutically acceptable salts, co-crystals, tautomers, stereoisomers, solvates, hydrates, polymorphs, isotopically labeled derivatives, prodrugs, and compositions thereof. Also provided are methods and kits involving the inventive lipidoid compounds, compositions, or formulations for treating and/or preventing diseases (e.g., genetic disease, proliferative disease, hematological disease, neurological disease, painful condition, psychiatric disorder, metabolic disorder, long-term medical condition, inflammatory disease, autoinflammatory disease, liver disease, lung disease, spleen disease, familial amyloid neuropathy, cardiovascular disease, viral infection, infectious disease, fibrotic condition, or autoimmune disease) in a subject, methods for synthesizing the compounds described herein, and compounds described herein synthesized by the synthetic methods described herein. The compounds are effective carriers for the delivery of an agent such as a polynucleotide (e.g., RNA) to a cell. |
| FILED | Friday, August 30, 2019 |
| APPL NO | 16/556470 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) A61K 2039/53 (20130101) A61K 2039/55555 (20130101) Acyclic or Carbocyclic Compounds C07C 237/06 (20130101) C07C 251/08 (20130101) Heterocyclic Compounds C07D 233/40 (20130101) Original (OR) Class C07D 403/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459308 | Bowlin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Microbiotix, Inc. (Worcester, Massachusetts); Albert Einstein College Of Medicine, Inc. (Bronx, New York); The Government Of The United States As Represented By The Secretary Of The Army (Fort Detrick, Maryland) |
| ASSIGNEE(S) | Microbiotix, Inc. (Worcester, Massachusetts); Albert Einstein College of Medicine (Bronx, New York); The Government of the United States as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Terry L. Bowlin (Maineville, Ohio); Donald T. Moir (Concord, Massachusetts); Kartik Chandran (Brooklyn, New York); John M. Dye, Jr. (Frederick, Maryland); John D. Williams (Fulton, Maryland); Zachary D. Aron (Acton, Massachusetts); Jay P. Barbor (Worcester, Massachusetts); Kelly N. Lively (Holliston, Massachusetts); Peter J. Nash (Newton, Massachusetts); Debra M. Mills (Francestown, New Hampshire); Arnab Basu (Acton, Massachusetts) |
| ABSTRACT | The present invention is related to the development of therapeutics and prophylactics for the treatment and/or prevention of filovirus infection in humans and other mammals. A new class of small molecules is disclosed that inhibits the interaction of naturally processed (i.e., proteolytically cleaved) filovirus glycoprotein (GPCL) with its host receptor Niemann-Pick C1 (NPC1) protein and thus block infection of host cells by filoviruses. Also disclosed are methods of using the small molecule inhibitors in the treatment/prevention of filovirus infection. |
| FILED | Tuesday, December 05, 2017 |
| APPL NO | 16/348033 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/00 (20130101) A61K 9/0014 (20130101) A61K 9/0029 (20130101) A61K 9/0053 (20130101) A61K 31/54 (20130101) A61K 31/437 (20130101) A61K 31/454 (20130101) A61K 31/496 (20130101) A61K 31/551 (20130101) A61K 31/4184 (20130101) A61K 31/4375 (20130101) A61K 31/5375 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Heterocyclic Compounds C07D 401/04 (20130101) Original (OR) Class C07D 401/14 (20130101) C07D 403/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459342 | Peterson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Combat Capabilities Development Command, Chemical Biological Center (Apg, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Gregory W Peterson (Belcamp, Maryland); Thomas H Epps, III (Newark, Delaware) |
| ABSTRACT | A composition having the structure of formula I: [R—Ar—(COOH)2]x[Ar—(COOH)3]2-xM32+ (I) is provided where M is Mn, Cu, Co, Fe, Zn, Cd, Ni, or Pt; R is a bromine, nitro, a primary amine, C1-C4 alkyl secondary amine, C1-C4 alkyl oxy, Br—(C1-C4 alkyl), NO2—(C1-C4 alkyl), a mercaptan, and reaction products of any of the aforementioned with acyl chlorides of the formulas: CH3(CH2)mC(O)Cl, or CH3(CH(C1-C4 alkyl)CH2)mC(O)Cl, or CH3(CH2)m-Ph-(CH2)pC(O)Cl, where Ph is a C6 phenyl or C6 phenyl with one or more hydrogens replaced with F, C1-C4 fluoroalkyl, or C1-C4 perfluoroalkyl; m is independently in each occurrence an integer of 0 to 12 inclusive; p is an integer of 0 to 36 inclusive, to form an amide, a thioamide, or an ester; Ar is a 1,3,5-modified phenyl, and 1.4>x>0. A process of synthesis thereof and the use to chemically modify a gaseous reactant are also provided. |
| FILED | Tuesday, December 10, 2019 |
| APPL NO | 16/709258 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/58 (20130101) B01D 53/62 (20130101) B01D 67/0079 (20130101) B01D 69/12 (20130101) B01D 71/022 (20130101) B01D 71/82 (20130101) B01D 2257/93 (20130101) B01D 2257/406 (20130101) B01D 2257/504 (20130101) B01D 2258/0283 (20130101) B01D 2323/39 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 1/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459381 | Claffey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF CONNECTICUT (Farmington, Connecticut) |
| ASSIGNEE(S) | UNIVERSITY OF CONNECTICUT (Farmington, Connecticut) |
| INVENTOR(S) | Kevin P. Claffey (Burlington, Connecticut); Charan Devarakonda (Willimantic, Connecticut); Daniel Kita (Cheshire, Connecticut) |
| ABSTRACT | Described herein is an isolated antibody or antigen-binding fragment including a heavy chain variable region including three heavy chain complementary determining regions (HCDRs), wherein the sequence of HCDR1 is GYRLSELS (SEQ ID NO: 1), the sequence of HCDR2 is ISGWDGNT (SEQ ID NO: 2), and the sequence of HCDR3 is ARASGYNY (SEQ ID NO: 3), wherein the isolated antibody or antigen-binding fragment specifically binds human HSP90, specifically HSP90 beta. Also included are detection and therapeutic methods using the isolated antibodies or antigen-binding fragments. |
| FILED | Wednesday, August 07, 2019 |
| APPL NO | 16/533937 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/18 (20130101) Original (OR) Class C07K 16/28 (20130101) C07K 16/3015 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) C07K 2317/569 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57492 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459473 | Shah et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Ramille N. Shah (Hinsdale, Illinois); Adam E. Jakus (Chicago, Illinois) |
| ABSTRACT | 3D printable ink compositions for forming objects, films and coatings are provided. Also provided are methods of printing the ink compositions and methods for making the ink compositions. The ink compositions include an elastic polymer binder and may have high loadings of solid particles. |
| FILED | Wednesday, January 22, 2020 |
| APPL NO | 16/749062 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/165 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2067/00 (20130101) B29K 2105/16 (20130101) B29K 2505/00 (20130101) B29K 2507/04 (20130101) B29K 2509/02 (20130101) B29K 2511/00 (20130101) B29K 2995/0046 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/03 (20130101) C09D 11/033 (20130101) C09D 11/037 (20130101) C09D 11/104 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459484 | Kidwell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | David A. Kidwell (Alexandria, Virginia); Thomas O'Shaughnessy (Arlington, Virginia) |
| ABSTRACT | A mixed acrylate-siloxane polymer can be used to create three-dimensional (3D) structures of arbitrary shape via nanolithography. Treatment of such structures with amine (such as diamine) makes them permissive for neuronal cell adhesion and growth without need of additional modification such as poly-lysine (D or L) nor laminin. |
| FILED | Tuesday, April 28, 2020 |
| APPL NO | 16/860426 |
| ART UNIT | 1787 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 17/32 (20130101) C03C 2218/32 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 133/08 (20130101) C09D 183/04 (20130101) Original (OR) Class Apparatus for Enzymology or Microbiology; C12M 25/14 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/70058 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459573 | Chan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Tsz Yan Clement Chan (Quincy, Massachusetts); James J. Collins (Newton, Massachusetts); Jeong Wook Lee (Brighton, Massachusetts); Douglas Ewen Cameron (Brookline, Massachusetts) |
| ABSTRACT | Provided herein are systems, methods and compositions for rendering cells or the expression of an effector protein sensitive to a predetermined condition. In one aspect, cells can be rendered dependent upon the presence of an environmental agent, e.g., an exogenous agent, without which the cell will default to expression of a death protein and be killed. In another aspect, cells can be rendered sensitive to the presence of a set of predetermined conditions such that cells will only grow when two or more necessary exogenous agents are supplied, and without either of which, the cells are killed. In this aspect, hybrid transcription factors provide a vast array of possible predetermined conditions. |
| FILED | Friday, September 30, 2016 |
| APPL NO | 15/764752 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/70 (20130101) Original (OR) Class C12N 15/635 (20130101) Computer Systems Based on Specific Computational Models G06N 3/123 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459744 | Swope et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Government as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Brandon Lawson Swope (San Diego, California); Leonard David Sinfield (Rail Road Flat, California); Patrick John Earley (San Diego, California); Alexander Gregory Stevens-Bracy (Chula Vista, California) |
| ABSTRACT | A filter for filtering storm water in an outfall pipe comprising: a line comprising an anchor attachment point at a proximal end of the line; and a plurality of individual treatment units (ITUs) securely connected in series to the line with a gap between adjacent ITUs, wherein each ITU has a size and shape capable of fitting inside the outfall pipe, and wherein each ITU comprises a mesh cage configured to filter contaminants out of the storm water. |
| FILED | Monday, January 04, 2021 |
| APPL NO | 17/140982 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 29/25 (20130101) B01D 2201/325 (20130101) B01D 2201/0415 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/001 (20130101) C02F 2103/001 (20130101) Sewers; Cesspools E03F 5/0404 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459902 | Tait et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Christopher Tait (San Mateo, California); Pejman Akbari (Pasadena, California); Brian Sell (Oakwood, Ohio); Marc Polanka (Wright-Patterson AFB, Ohio) |
| ABSTRACT | A unique seal for a wave rotor disk engine is disclosed herein. The seal is operable for sealing a region between a rotor and a rotor casing. The seal is spring loaded and will engage with the tip of the rotor to reduce pressure loss within the wave rotor disk engine. |
| FILED | Tuesday, January 07, 2020 |
| APPL NO | 16/736223 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/001 (20130101) Original (OR) Class F01D 11/005 (20130101) F01D 11/08 (20130101) F01D 11/16 (20130101) F01D 25/246 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/28 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/60 (20130101) F05D 2240/11 (20130101) F05D 2240/55 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11460248 | Johnson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Terumo BCT Biotechnologies, LLC (Lakewood, Colorado) |
| ASSIGNEE(S) | Terumo BCT Biotechnologies, LLC (Lakewood, Colorado) |
| INVENTOR(S) | Nathaniel T. Johnson (Highlands Ranch, Colorado); Rylan A. Summit (Denver, Colorado); Dennis A. Bridges (Arvada, Colorado); Dennis J. Hlavinka (Arvada, Colorado); Kestas P. Parakininkas (Englewood, Colorado); Kirk L. Weimer (Green Valley, Arizona); Michael Lawrence Glover (Lakewood, Colorado); Alexander Du Nguyen (Denver, Colorado); Margaret V. Kwiat (Evergreen, Colorado) |
| ABSTRACT | Provided is a gas fill fixture for use in lyophilization, a related system and method. The gas fill fixture includes a chassis, fill indicator and a lid, such that the chassis and lid together form a cavity for receiving a flexible lyophilization container. The system includes a lyophilization container, a lyophilizer and a gas fill fixture incorporating a chassis, a fill indicator and a lid. The method includes process steps for using the system to lyophilize a fluid. |
| FILED | Wednesday, March 11, 2020 |
| APPL NO | 16/815904 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0252 (20130101) A01N 1/0263 (20130101) A01N 1/0284 (20130101) A01N 1/0289 (20130101) Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 1/10 (20130101) A61J 1/1468 (20150501) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/0277 (20140204) A61M 2202/0415 (20130101) A61M 2205/584 (20130101) A61M 2205/3389 (20130101) Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 51/241 (20130101) Drying Solid Materials or Objects by Removing Liquid Therefrom F26B 5/06 (20130101) Original (OR) Class F26B 21/14 (20130101) F26B 25/18 (20130101) F26B 25/063 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11460282 | Wade et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Department of the Navy (Indian Head, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | James Wade (Waldorf, Maryland); Angel Diaz (Indian Head, Maryland); Lee Foltz (Indian Head, Maryland); Daniel McCarthy (LaPlata, Maryland) |
| ABSTRACT | An insensitive munition initiation canister includes a first cylindrical body having an external surface, which includes a first set of threads arranged circumferentially around the first cylindrical body, and a second cylindrical body connected to the first cylindrical body including an external surface having a second set of threads arranged circumferentially around the second cylindrical body. The first cylindrical body includes a first internal region set to retain an explosive charge having a detonation capability sufficient to detonate an insensitive munition. The first cylindrical body is set to sit inside a munition fuze well. The threads of the first cylindrical body are set to engage the munition fuze well. |
| FILED | Friday, September 29, 2017 |
| APPL NO | 15/732175 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 3/11 (20130101) Ammunition Fuzes; Arming or Safety Means Therefor F42C 15/188 (20130101) F42C 19/02 (20130101) F42C 19/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11460399 | Terracciano et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Anthony Terracciano (Orlando, Florida); Robert Peale (Orlando, Florida); Christopher Arose (Orlando, Florida); Subith Vasu (Orlando, Florida) |
| ABSTRACT | A method and device which can receive and identify electromagnetic radiation in the terahertz (THz) frequency range. The device has a combination of material and geometric parameters that are unique and tunable, enabling resonating frequencies for spectral selectivity in the THz range (0.1-15) with ultra-narrow channel widths (0.01-0.10 THz) full width at half maximum (FWHM). Dependent upon configuration, the device may be employed as a large area resonator to collect weak or diffuse signals or as a constituent of an array able to take pictures within the spectrum for which they are sensitive. |
| FILED | Tuesday, April 13, 2021 |
| APPL NO | 17/228801 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/34 (20130101) G01J 2005/345 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/3581 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 37/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11460430 | Hagen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Cincinnati (Cincinnati, Ohio) |
| ASSIGNEE(S) | University Of Cincinnati (Cincinnati, Ohio) |
| INVENTOR(S) | Joshua A. Hagen (Cincinnati, Ohio); Jason Charles Heikenfeld (Cincinnati, Ohio); Ian Papautsky (Willowbrook, Illinois); Linlin Hou (Portland, Ohio); Rajesh Naik (Centerville, Ohio); Nancy Kelley-Loughnane (Cincinnati, Ohio); Morley O. Stone (Columbus, Ohio); John Busbee (Washington Township, Ohio); Xiao Wang (Waltham, Massachusetts) |
| ABSTRACT | Biological chemicals, potentially found in blood are measured by collecting sweat and determining the concentration or meaning of the selected chemical in sweat. The sweat can be collected using a time based, interval collector and analyzed using an external device. It can also be collected on a one time basis, using a flexible, chemical capacitor, or on a continuous basis using a chemical, field effect transducer. |
| FILED | Wednesday, April 03, 2013 |
| APPL NO | 14/388416 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0002 (20130101) A61B 5/681 (20130101) A61B 5/1477 (20130101) A61B 5/14517 (20130101) A61B 5/14532 (20130101) A61B 5/14546 (20130101) A61B 10/0064 (20130101) A61B 10/0096 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/5023 (20130101) B01L 2200/0621 (20130101) B01L 2300/022 (20130101) B01L 2300/023 (20130101) B01L 2300/069 (20130101) B01L 2300/0645 (20130101) B01L 2300/0803 (20130101) B01L 2300/0864 (20130101) B01L 2400/086 (20130101) B01L 2400/0406 (20130101) B01L 2400/0677 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3273 (20130101) Original (OR) Class G01N 27/4145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11460505 | Patrissi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (, None) |
| INVENTOR(S) | Charles J Patrissi (Newport, Rhode Island); Jason L Mercier (Middletown, Rhode Island) |
| ABSTRACT | A modified battery cell for simulating failure conditions includes an electrical cell and a controllable voltage source. A transistor gate is joined to a positive output of the source and to a negative tab of the cell at the transistor source. One side of a resistor implanted in the cell is joined to the transistor drain and the other side is joined to the cell positive tab. Controlling voltage source voltage allows current to flow from the transistor source to the transistor drain and through the resistor. Current flow through the resistor causes heating within the electrical cell that can be monitored to simulate an electrical cell failure. A method for testing an electrical cell is also provided. |
| FILED | Tuesday, April 07, 2020 |
| APPL NO | 16/841718 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/382 (20190101) G01R 31/3644 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/486 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11460526 | Foo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GE PRECISION HEALTHCARE LLC (Wauwatosa, Wisconsin) |
| ASSIGNEE(S) | GE PRECISION HEALTHCARE LLC (Wauwatosa, Wisconsin) |
| INVENTOR(S) | Thomas Kwok-Fah Foo (Clifton Park, New York); Matthew Richard Tarasek (Niskayuna, New York); Desmond Teck Beng Yeo (Clifton Park, New York) |
| ABSTRACT | A pulse sequence generation computing device for a magnetic resonance imaging (MRI) system includes a processor in communication with a memory device. The processor is programmed to receive a pulse sequence including a plurality of gradient pulses and provide a pulse sequence threshold function corresponding to an acoustic noise reduction level. For each gradient pulse in the pulse sequence, the processor is programmed to determine an amplitude and a slew rate of the gradient pulse, determine a threshold amplitude and slew rate of the gradient pulse, and compare the determined amplitude and slew rate to the threshold amplitude and slew rate. If either the determined amplitude or slew rate exceeds the threshold amplitude or slew rate, the processor adjusts at least one of the amplitude and the slew rate of the gradient pulse to an amplitude and a slew rate as defined by the pulse sequence threshold function. |
| FILED | Thursday, April 29, 2021 |
| APPL NO | 17/244237 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/3854 (20130101) Original (OR) Class G01R 33/5618 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11460685 | Hillman |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trusteees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Elizabeth M. C. Hillman (New York, New York) |
| ABSTRACT | Methods, devices and systems for up to three-dimensional scanning of target regions at high magnification are disclosed. |
| FILED | Wednesday, September 30, 2020 |
| APPL NO | 17/038902 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/0032 (20130101) G02B 21/0052 (20130101) G02B 21/361 (20130101) G02B 21/367 (20130101) Original (OR) Class G02B 23/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11460753 | Hughes et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Tyler William Hughes (Stanford, California); Momchil Minkov (Stanford, California); Ian Williamson (Stanford, California); Shanhui Fan (Stanford, California) |
| ABSTRACT | Systems and methods for activation in an optical circuit in accordance with embodiments of the invention are illustrated. One embodiment includes an optical activation circuit, wherein the circuit comprises a directional coupler, an optical-to-electrical conversion circuit, a time delay element, a nonlinear signal conditioner, and a phase shifter. The directional coupler receives an optical input and provides a first portion to the optical-to-electrical conversion circuit and a second portion to the time delay element, the time delay element provides a delayed signal to the phase shifter, and the optical-to-electrical conversion circuit converts an optical signal from the directional coupler to an electrical signal used to activate the phase shifter to shift the phase of the delayed signal. |
| FILED | Friday, May 10, 2019 |
| APPL NO | 17/054127 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/365 (20130101) G02F 1/3517 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/0481 (20130101) G06N 3/0675 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11460861 | Fox et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (Indianapolis, Indiana) |
| INVENTOR(S) | Geoffrey C. Fox (Bloomington, Indiana); Supun M. Kamburugamuve Loku Acharige (Bloomington, Indiana) |
| ABSTRACT | A method of controlling an operation of a robot (102) is provided using a cluster of nodes (104) in a network (106). The method includes receiving, using a gateway cloud driver (108), robot state information from the robot (102) via the network (106), and converting, using the gateway cloud driver (108), the robot state information into at least one message. The method further includes transmitting, using a message broker (110), the at least one message to the cluster of nodes (104) via the network (106). The method further includes processing, using the cluster of nodes (104) in the network (106), the at least one message by parallel computing, and generating, using the cluster of nodes (104) in the network (106), a robot command to control the operation of the robot (102). |
| FILED | Friday, February 16, 2018 |
| APPL NO | 16/486104 |
| ART UNIT | 3665 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 60/001 (20200201) B60W 2554/4042 (20200201) B60W 2554/4043 (20200201) B60W 2556/45 (20200201) Systems for Controlling or Regulating Non-electric Variables G05D 1/0088 (20130101) G05D 1/0289 (20130101) G05D 1/0291 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 67/125 (20130101) H04L 67/1002 (20130101) H04L 67/2809 (20130101) H04L 67/2823 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11461048 | Brewer |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | Tony M. Brewer (Plano, Texas) |
| ABSTRACT | A memory controller circuit is disclosed which is coupleable to a first memory circuit, such as DRAM, and includes: a first memory control circuit to read from or write to the first memory circuit; a second memory circuit, such as SRAM; a second memory control circuit adapted to read from the second memory circuit in response to a read request when the requested data is stored in the second memory circuit, and otherwise to transfer the read request to the first memory control circuit; predetermined atomic operations circuitry; and programmable atomic operations circuitry adapted to perform at least one programmable atomic operation. The second memory control circuit also transfers a received programmable atomic operation request to the programmable atomic operations circuitry and sets a hazard bit for a cache line of the second memory circuit. |
| FILED | Monday, December 21, 2020 |
| APPL NO | 17/128862 |
| ART UNIT | 2138 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0604 (20130101) G06F 3/0659 (20130101) Original (OR) Class G06F 3/0683 (20130101) G06F 12/0875 (20130101) G06F 2212/452 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11461097 | Martínez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | José F. Martínez (Ithaca, New York); Helena Caminal (Ithaca, New York); Kailin Yang (Ithaca, New York); Khalid Al-Hawaj (Ithaca, New York); Christopher Batten (Ithaca, New York) |
| ABSTRACT | A content-addressable processing engine, also referred to herein as CAPE, is provided. Processing-in-memory (PIM) architectures attempt to overcome the von Neumann bottleneck by combining computation and storage logic into a single component. CAPE provides a general-purpose PIM microarchitecture that provides acceleration of vector operations while being programmable with standard reduced instruction set computing (RISC) instructions, such as RISC-V instructions with standard vector extensions. CAPE can be implemented as a standalone core that specializes in associative computing, and that can be integrated in a tiled multicore chip alongside other types of compute engines. Certain embodiments of CAPE achieve average speedups of 14× (up to 254×) over an area-equivalent out-of-order processor core tile with three levels of caches across a diverse set of representative applications. |
| FILED | Friday, January 15, 2021 |
| APPL NO | 17/149936 |
| ART UNIT | 2183 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 9/3001 (20130101) G06F 9/3004 (20130101) G06F 9/30036 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11461373 | Skarin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Aptima, Inc. (Woburn, Massachusetts) |
| ASSIGNEE(S) | Aptima, Inc. (Woburn, Massachusetts) |
| INVENTOR(S) | Bruce Skarin (Millbury, Massachusetts); Andrew Duchon (Portland, Oregon); Richard Alexis DeJordy (Stoughton, Massachusetts); Paul David Allopenna (Storrs-Mansfield, Connecticut) |
| ABSTRACT | Embodiments of the subject invention comprise a computer based system and methods to collect and compare the attributes of a group of entities using data representing topic data of the entity and interaction data between entities. Embodiments of the invention comprise using minimally invasive means to automatically collect and model both an entity's attributes such as their knowledge/work/interest as well as model the social interactions of the entity together with a means to identify opportunities to influence changes in the entity attributes. Minimally invasive means to collect and model attributes include semantic analysis and topic modeling techniques. Means to model social interactions include social network analysis techniques that can incorporate location data of the entity. Embodiments of the invention further provide a sharable index of the attributes of the entities and the group of entities. |
| FILED | Wednesday, March 08, 2017 |
| APPL NO | 15/452781 |
| ART UNIT | 2169 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/22 (20190101) G06F 16/288 (20190101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11461511 | Gecer Ulu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Nurcan Gecer Ulu (Sunnyvale, California); Svyatoslav Korneev (Stanford, California); Saigopal Nelaturi (Mountain View, California); Erva Ulu (Sunnyvale, California) |
| ABSTRACT | A method for producing a design includes receiving a set of design constraints. A spatial field is created based on the design constraints. The spatial field is represented with a linear combination of one or more bases. A number of the one or more bases is less than a number of elements in the spatial field. Respective weights are optimized for each of the one or more bases. A design is produced based on the spatial field and the weights. |
| FILED | Friday, March 13, 2020 |
| APPL NO | 16/818379 |
| ART UNIT | 2147 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 30/12 (20200101) Original (OR) Class G06F 2111/02 (20200101) G06F 2111/04 (20200101) G06F 2111/10 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11461527 | Brewer |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | Tony M. Brewer (Plano, Texas) |
| ABSTRACT | A representative system, apparatus, method and protocol are disclosed for data communication between chiplets or SOCs on a common interposer. A representative system comprises: an interposer; a first integrated circuit arranged on the interposer, the first integrated circuit comprising a first common protocol interface circuit; a communication link coupled to the first common protocol interface circuit; and a second integrated circuit arranged on the interposer, the second integrated circuit comprising a second common protocol interface circuit coupled to the communication link to form a serial protocol interface between the first common protocol interface circuit and the second common protocol interface circuit. Serial data and control packets and parallel data and control packets having specified, ordered fields are also disclosed. |
| FILED | Saturday, February 02, 2019 |
| APPL NO | 16/266033 |
| ART UNIT | 2465 — Multiplex and VoIP |
| CURRENT CPC | Electric Digital Data Processing G06F 30/394 (20200101) Original (OR) Class Static Stores G11C 7/1045 (20130101) G11C 11/409 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/40 (20220501) H04L 69/12 (20130101) H04L 69/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11461592 | Javidi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | University of Connecticut (Farmington, Connecticut) |
| INVENTOR(S) | Bahram Javidi (Mansfield, Connecticut); Adam Markman (Orange, Connecticut) |
| ABSTRACT | Described herein is an object recognition system in low illumination conditions. A 3D InIm system can be trained in the low illumination levels to classify 3D objects obtained under low illumination conditions. Regions of interest obtained from 3D reconstructed images are obtained by de-noising the 3D reconstructed image using total-variation regularization using an augmented Lagrange approach followed by face detection. The regions of interest are then inputted into a trained CNN. The CNN can be trained using 3D InIm reconstructed under low illumination after TV-denoising. The elemental images were obtained under various low illumination conditions having different SNRs. The CNN can effectively recognize the 3D reconstructed faces after TV-denoising. |
| FILED | Wednesday, August 07, 2019 |
| APPL NO | 17/251327 |
| ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6257 (20130101) Original (OR) Class Image or Video Recognition or Understanding G06V 10/25 (20220101) G06V 10/143 (20220101) G06V 20/647 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11461593 | Tuor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Tiffany Tuor (London, United Kingdom); Shiqiang Wang (White Plains, New York); Changchang Liu (White Plains, New York); Bong Jun Ko (Harrington Park, New Jersey); Wei-Han Lee (White Plains, New York) |
| ABSTRACT | A method, a computer program product, and a computer system determine when to perform a federated learning process. The method includes identifying currently available contributors among contributors of a federated learning task for which the federated learning process is to be performed. The method includes determining a usefulness metric of the currently available contributors for respective datasets from each of the currently available contributors used in performing the federated learning process. The method includes, as a result of the usefulness metric of the currently available contributors being at least a usefulness threshold, generating a recommendation to perform the federated learning process with the datasets of the currently available contributors. The method includes transmitting the recommendation to a processing component configured to perform the federated learning process. |
| FILED | Tuesday, November 26, 2019 |
| APPL NO | 16/695268 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6259 (20130101) Original (OR) Class G06K 9/6267 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/049 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/103 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11461618 | Sussillo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | David Sussillo (Portola Valley, California); Jonathan C. Kao (Stanford, California); Sergey Stavisky (San Francisco, California); Krishna V. Shenoy (Palo Alto, California) |
| ABSTRACT | A brain machine interface (BMI) to control a device is provided. The BMI has a neural decoder, which is a neural to kinematic mapping function with neural signals as input to the neural decoder and kinematics to control the device as output of the neural decoder. The neural decoder is based on a continuous-time multiplicative recurrent neural network, which has been trained as a neural to kinematic mapping function. An advantage of the invention is the robustness of the decoder to perturbations in the neural data; its performance degrades less—or not at all in some circumstances—in comparison to the current state decoders. These perturbations make the current use of BMI in a clinical setting extremely challenging. This invention helps to ameliorate this problem. The robustness of the neural decoder does not come at the cost of some performance, in fact an improvement in performance is observed. |
| FILED | Monday, March 04, 2019 |
| APPL NO | 16/292000 |
| ART UNIT | 2127 — AI & Simulation/Modeling |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/24 (20210101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) G06N 3/0445 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11461881 | Parameswaran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States Government as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Shibin Parameswaran (San Diego, California); Martin Thomas Jaszewski (San Diego, California) |
| ABSTRACT | A method for processing images comprising: capturing a plurality of degraded images of a first real-world environment with a first sensor; processing each degraded image with a first, untrained convolutional neural network, via a Deep Image Prior approach, to obtain a plurality of clean images, wherein each clean image corresponds to a degraded image; pairing each clean image with its corresponding degraded image to create a plurality of degraded/clean image pairs; training, via a supervised learning approach, a machine learning model to learn a function for converting degraded images into restored images based on the plurality of degraded/clean image pairs; capturing a second plurality of degraded images of a second real-world environment; and using the trained machine learning model to convert the second plurality of degraded images into restored images based on the learned function. |
| FILED | Wednesday, November 25, 2020 |
| APPL NO | 17/105135 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/50 (20130101) Original (OR) Class G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11461891 | Madabhushi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Cristian Barrera (Bogota, Colombia); German Corredor (Bogota, Colombia); Eduardo Romero (Bogota, Colombia) |
| ABSTRACT | Embodiments include controlling a processor to access an image of a region of tissue demonstrating cancerous pathology; segment a cellular nucleus represented in the image; extract a first set of features from the segmented cellular nucleus; classify the segmented nucleus as a lymphocyte or non-lymphocyte based on the first set of features; for a segmented nucleus classified as a lymphocyte: computing a set of contextual features; assign the segmented nucleus classified as a lymphocyte to one of a plurality of clusters based on the set of contextual features; compute a frequency distribution of the clustered segmented nuclei classified as lymphocytes; provide the frequency distribution to a machine learning classifier; receive, from the machine learning classifier, a classification of the region of tissue as likely to experience recurrence or unlikely to experience recurrence, based, at least in part, on the frequency distribution; and display the classification. |
| FILED | Thursday, January 31, 2019 |
| APPL NO | 16/263334 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6228 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 2207/10056 (20130101) G06T 2207/20081 (20130101) G06T 2207/30024 (20130101) G06T 2207/30061 (20130101) G06T 2207/30096 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 40/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11462358 | Lewis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Laura H. Lewis (Boston, Massachusetts); Ian J. McDonald (Weatherly, Pennsylvania); Sahar Keshavarz (Hillsboro, Oregon); R. William McCallum (Santa Fe, New Mexico) |
| ABSTRACT | The invention provides method for making high coercivity magnetic materials based on FeNi alloys having a L10 phase structure, tetratenite, and provides a system for accelerating production of these materials. The FeNi alloy is made by preparing a melt comprising Fe, Ni, and optionally one or more elements selected from the group consisting of Ti, V, Al, B, C, Mo, Ir, and Nb; cooling the melt and applying extensional stress and a magnetic field. This is followed by heating and cooling to form the L10 structure. |
| FILED | Monday, August 20, 2018 |
| APPL NO | 16/639844 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 6/001 (20130101) C21D 8/1233 (20130101) Alloys C22C 33/04 (20130101) C22C 38/08 (20130101) C22C 38/12 (20130101) C22C 2202/02 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/14708 (20130101) H01F 41/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11462402 | Vogt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York); The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York); The Penn State Research Foundation (University Park, Panama) |
| INVENTOR(S) | Patrick Vogt (Ithaca, New York); Darrell G. Schlom (Ithaca, New York); Felix V. E. Hensling (Ithaca, New York); Kathy Azizie (Plainfield, New Jersey); Zi-Kui Liu (State College, Pennsylvania); Brandon J. Bocklund (State College, Pennsylvania); Shun-Li Shang (State College, Pennsylvania) |
| ABSTRACT | Molecular-beam epitaxy (MBE) and more particularly suboxide MBE (S-MBE) and related structures are disclosed. S-MBE is disclosed that includes the use of a molecular beam of a suboxide that may be subsequently oxidized in a single step reaction to form an oxide film. By way of example, for a gallium oxide (Ga2O3) film, a molecular beam including a suboxide of gallium (Ga2O) may be provided. S-MBE may be performed in adsorption-controlled regimes where there is an excess of source material containing species in order to promote high growth rates for oxide films with improved crystallinity. Source mixtures for providing molecular beams of suboxides are disclosed that include mixtures of a particular element and an oxide of the element in ratios that promote such adsorption-controlled growth regimes. Related structures include oxide films having increased thickness with reduced crystal defects, including single polymorph films of gallium oxide. |
| FILED | Wednesday, October 21, 2020 |
| APPL NO | 17/076011 |
| ART UNIT | 2816 — Semiconductors/Memory |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 23/066 (20130101) C30B 29/16 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02565 (20130101) H01L 21/02631 (20130101) Original (OR) Class H01L 29/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11462682 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Jian-Ping Wang (Shoreview, Minnesota); Thomas Jon Peterson (Lauderdale, Minnesota); Anthony William Hurben (Bloomington, Minnesota); Delin Zhang (Saint Paul, Minnesota) |
| ABSTRACT | A magnetic device may include a layer stack including a work function structure, a dielectric layer, and a ferromagnetic layer, where the ferromagnetic layer is positioned between the work function structure and the dielectric layer. The work function structure is configured to deplete electrons from the ferromagnetic layer or accumulate electrons in the ferromagnetic layer. A magnetization orientation of the ferromagnetic layer is configured to be switched by a voltage applied across the layer stack or by a voltage applied across or through the work function structure. |
| FILED | Friday, February 19, 2021 |
| APPL NO | 17/249105 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/049 (20130101) Static Stores G11C 11/161 (20130101) G11C 11/1673 (20130101) G11C 11/1675 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/222 (20130101) H01L 43/02 (20130101) H01L 43/10 (20130101) Original (OR) Class H01L 43/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11462729 | Carney et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Thomas J. Carney (Cambridge, Massachusetts); Fikile Richard Brushett (Cambridge, Massachusetts) |
| ABSTRACT | Embodiments related to electrodes comprising composite mixtures and related devices (e.g., convection batteries), systems, and methods are disclosed. |
| FILED | Friday, April 12, 2019 |
| APPL NO | 16/383525 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/045 (20130101) H01M 4/362 (20130101) Original (OR) Class H01M 2004/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11462869 | Stumme et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Anna Stumme (Washington, District of Columbia); William Mark Dorsey (Ellicott City, Maryland); John A. Valenzi (Alexandria, Virginia) |
| ABSTRACT | A novel, interlocking, snap-fit connection between an antenna aperture and a ground plane layer that contains coaxial connectors is described herein. The snap-fit design provides a simple and solderless transition from the connectors to elements of the antenna aperture. This design facilitates easy assembly and disassembly, allowing parts to be removed, reinstalled and/or reused. |
| FILED | Friday, May 01, 2020 |
| APPL NO | 16/864719 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/36 (20130101) H01Q 1/48 (20130101) H01Q 1/088 (20130101) H01Q 21/0025 (20130101) Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 13/6278 (20130101) H01R 24/52 (20130101) Original (OR) Class H01R 2201/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11462879 | Murphy et al. |
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| FUNDED BY |
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| APPLICANT(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Robert H. Murphy (Lancaster, Massachusetts); Michael D. Joswick (Bedford, New Hampshire); Susan Palmateer (Harvard, Massachusetts) |
| ABSTRACT | A system and method for enhancing laser contrast on a remote target utilizing an image processor and a laser power controller is provided. An image processor in an imaging device manipulates a laser power controller in a laser system so that a laser beam emitted from a laser system is ultimately synchronized with the imaging device. Firstly, the original laser signal is shifted one time frame relative to the plurality of time frames to create a shifted laser signal. Secondly, the shifted laser signal is subtracted from the original laser signal. Thirdly, the subtracted laser signal is magnified by a frequency band pass filter. The filtered laser signal is added to the original signal to become the finalized laser signal which has better contrast than the original signal. |
| FILED | Wednesday, July 05, 2017 |
| APPL NO | 16/628464 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/4257 (20130101) G01J 2001/4238 (20130101) Optical Elements, Systems, or Apparatus G02B 27/20 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/10015 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 5/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11462939 | Kuklinski et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (, None) |
| INVENTOR(S) | Robert Kuklinski (Portsmouth, Rhode Island); Anthony A Ruffa (Hope Valley, Rhode Island) |
| ABSTRACT | An energy harvesting system is positionable at an ocean surface to harvest energy from a hydrothermal vent surrounded by cooler ocean water. The system includes an energy storage device positionable proximate to the ocean surface. A cable capable of conducting electrical energy is joined to the energy storage device. An energy harvesting structure is joined to provide electrical energy to the cable. The energy harvesting structure can be positioned proximate to the hydrothermal vent to harvest energy therefrom. |
| FILED | Friday, July 24, 2020 |
| APPL NO | 16/937682 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 35/44 (20130101) B63B 2035/4466 (20130101) Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 7/05 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/28 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0013 (20130101) H02J 50/001 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11463261 | Kaddoura |
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| FUNDED BY |
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| APPLICANT(S) | ARCHITECTURE TECHNOLOGY CORPORATION (Eden Prairie, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Maher N. Kaddoura (Maple Grove, Minnesota) |
| ABSTRACT | Software configured to receive a first record is provided. The first record includes first record data, a first identification code in an identification code field, a first hash in a record hash field, and a second hash in a previous record pointer field. The first hash is calculated based on the first record data, the first identification code, and the second hash. The second hash is included in a record hash field of a second record. The second record includes the first identification code in its identification code field. A first block is generated having the first record in a first record field, a third hash in a block hash field, and a fourth hash in a previous block pointer field. The third hash is calculated based on the first record and the fourth hash. The fourth hash is included in a block hash field of a second block. The second block is part of a main ledger that includes a third block having the second record in its record field. The third block is positioned prior to the second block in the main ledger. |
| FILED | Monday, December 14, 2020 |
| APPL NO | 17/121125 |
| ART UNIT | 2456 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/50 (20220501) H04L 9/0643 (20130101) H04L 9/3239 (20130101) Original (OR) Class H04L 9/3247 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11463272 | Klenk et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NVIDIA Corporation (Santa Clara, California) |
| ASSIGNEE(S) | NVIDIA Corporation (Santa Clara, California) |
| INVENTOR(S) | Benjamin Klenk (San Jose, California); Nan Jiang (Santa Clara, California); Larry Robert Dennison (Menden, Massachusetts); Gregory M. Thorson (Palo Alto, California) |
| ABSTRACT | A network device configured to perform scalable, in-network computations is described. The network device is configured to process pull requests and/or push requests from a plurality of endpoints connected to the network. A collective communication primitive from a particular endpoint can be received at a network device. The collective communication primitive is associated with a multicast region of a shared global address space and is mapped to a plurality of participating endpoints. The network device is configured to perform an in-network computation based on information received from the participating endpoints before forwarding a response to the collective communication primitive back to one or more of the participating endpoints. The endpoints can inject pull requests (e.g., load commands) and/or push requests (e.g., store commands) into the network. A multicast capability enables tasks, such as a reduction operation, to be offloaded to hardware in the network device. |
| FILED | Wednesday, October 06, 2021 |
| APPL NO | 17/495547 |
| ART UNIT | 2448 — Computer Networks |
| CURRENT CPC | Electric Digital Data Processing G06F 9/5083 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 12/18 (20130101) H04L 12/1886 (20130101) Original (OR) Class H04L 45/74 (20130101) H04L 47/20 (20130101) H04L 47/39 (20130101) H04L 47/806 (20130101) H04L 67/55 (20220501) H04L 67/568 (20220501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11463366 | Burnett et al. |
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| FUNDED BY |
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| APPLICANT(S) | Architecture Technology Corporation (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Architecture Technology Corporation (Minneapolis, Minnesota) |
| INVENTOR(S) | Benjamin L. Burnett (Prior Lake, Minnesota); Deborah K. Charan (Minneapolis, Minnesota); Ian J. McLinden (Minneapolis, Minnesota); Jordan C. Bonney (Bloomington, Minnesota) |
| ABSTRACT | This disclosure is directed to network optimization in a complex joint network for increasing the network utility of the complex joint network. A computing device in the complex joint network may receive a data flow via a complex joint network. The computing device may determine, based on a network template, a mission utility associated with the data flow and a traffic class associated with the data flow. The computing device may control one or more quality of service decisions based at least in part on the mission utility associated with the data flow and the traffic class associated with the data flow. |
| FILED | Tuesday, September 22, 2020 |
| APPL NO | 17/028664 |
| ART UNIT | 2459 — Computer Networks |
| CURRENT CPC | Transmission H04B 7/0617 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 41/0816 (20130101) H04L 41/0843 (20130101) H04L 41/0886 (20130101) H04L 45/02 (20130101) H04L 47/762 (20130101) H04L 47/781 (20130101) H04L 47/2441 (20130101) Original (OR) Class Wireless Communication Networks H04W 8/04 (20130101) H04W 16/28 (20130101) H04W 76/19 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11464137 | Chainer et al. |
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| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Timothy J. Chainer (Putnam Valley, New York); Pritish R. Parida (Stamford, Connecticut); Joel A. Silberman (Somers, New York) |
| ABSTRACT | A cooling system includes a device to be cooled and a cooling device integrated with the device to be cooled. A cooling volume has cavities and active coolant flow controls configured to adjust coolant flow through the cavities. A reservoir is in fluid communication with the cavities and has a liquid outlet and an inlet for a gas or gas-liquid mixture. A two-phase coolant is in the reservoir and cavities. The two-phase coolant has a phase transition temperature between an ambient temperature and an expected device temperature. A capacitance sensor is configured to determine a coolant capacitance in the cavities. A control module is configured to determine a vapor quality and void fraction of the coolant based on the measured capacitance and to increase coolant flow if the determined vapor quality and void fraction indicate a dry-out condition. A secondary cooling line removes heat from the cooling device. |
| FILED | Wednesday, May 16, 2018 |
| APPL NO | 15/981067 |
| ART UNIT | 2835 — Electrical Circuits and Systems |
| CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/06 (20130101) F28D 15/025 (20130101) F28D 15/0266 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20327 (20130101) H05K 7/20336 (20130101) H05K 7/20381 (20130101) Original (OR) Class H05K 7/20809 (20130101) H05K 7/20827 (20130101) H05K 7/20836 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11458431 | Long et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Jeffrey R. Long (Oakland, California); Phillip J. Milner (Ithaca, New York); Rebecca L. Siegelman (Berkeley, California) |
| ABSTRACT | An adsorption material is disclosed that comprises a metal-organic framework and a plurality of ligands. The metal-organic framework comprising a plurality of metal ions. Each respective ligand in the plurality of ligands is amine appended to a respective metal ion in the plurality of metal ions of the metal-organic framework. Each respective ligand in the plurality of ligands comprises a substituted 1,3-propanediamine. The adsorbent has a CO2 adsorption capacity of greater than 2.50 mmol/g at 150 mbar CO2 at 40° C. Moreover, the adsorbent is configured to regenerate at less than 120° C. An example ligand is diamine 2,2-dimethyl-1,3-propanediamine. An example of the metal-organic framework is Mg2(dobpdc), where dobpdc4− is 4,4′-dioxidobiphenyl-3,3′-dicarboxylate. Example applications for the adsorption material are removal of carbon dioxide from flue gas and biogasses. |
| FILED | Saturday, February 17, 2018 |
| APPL NO | 16/481039 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/02 (20130101) Original (OR) Class B01D 2253/204 (20130101) B01D 2257/504 (20130101) B01D 2258/05 (20130101) B01D 2259/4009 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/226 (20130101) B01J 20/3466 (20130101) B01J 20/3491 (20130101) B01J 20/28057 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11458542 | Scime et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Luke R. Scime (Knoxville, Tennessee); Vincent C. Paquit (Knoxville, Tennessee); Desarae J. Goldsby (Knoxville, Tennessee); William H. Halsey (Knoxville, Tennessee); Chase B. Joslin (Knoxville, Tennessee); Michael D. Richardson (Knoxville, Tennessee); Derek C. Rose (Knoxville, Tennessee); Derek H. Siddel (Knoxville, Tennessee) |
| ABSTRACT | Detection and classification of anomalies for powder bed metal additive manufacturing. Anomalies, such as recoater blade impacts, binder deposition issues, spatter generation, and some porosities, are surface-visible at each layer of the building process. A multi-scaled parallel dynamic segmentation convolutional neural network architecture provides additive manufacturing machine and imaging system agnostic pixel-wise semantic segmentation of layer-wise powder bed image data. Learned knowledge is easily transferrable between different additive manufacturing machines. The anomaly detection can be conducted in real-time and provides accurate and generalizable results. |
| FILED | Tuesday, November 17, 2020 |
| APPL NO | 16/950484 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/80 (20210101) Original (OR) Class Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/153 (20170801) B29C 64/386 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 50/02 (20141201) Image Data Processing or Generation, in General G06T 3/4046 (20130101) G06T 3/4053 (20130101) G06T 7/0004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459242 | Neale et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Nathan Richard Neale (Denver, Colorado); Gerard Zachary Carroll (Golden, Colorado); Gregory Frank Pach (Denver, Colorado); Maxwell Connor Schulze (Golden, Colorado); Trevor Russell Martin (Lakewood, Colorado) |
| ABSTRACT | The present disclosure relates to a silicon nanoparticle that includes a core of silicon having an outer surface that includes *SiH3-xRx, where *Si is a silicon atom on the outer surface of the core, the first layer covers at least a portion of the outer surface, R is a ligand that includes at least one of —O—R′, —C—R′, —N—R′, —Si—R′, and/or —S—R′, and R′ is a functional group that includes at least one of carbon, oxygen, nitrogen, hydrogen, sulfur, and/or phosphorus. |
| FILED | Wednesday, January 15, 2020 |
| APPL NO | 16/743389 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 33/12 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/64 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/386 (20130101) H01M 10/0525 (20130101) H01M 10/0562 (20130101) H01M 2300/0094 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459289 | Rorrer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Nicholas Rorrer (Golden, Colorado); Gregg Tyler Beckham (Golden, Colorado); Caroline Bradshaw Hoyt (Denver, Colorado) |
| ABSTRACT | The present disclosure relates to a composition that includes a first repeat unit defined by where R includes a first hydrocarbon chain that includes at least one olefinic bond, R5 includes a second hydrocarbon chain, the second hydrocarbon chain may be saturated, and n may be between 2 and 1,000. |
| FILED | Monday, August 17, 2020 |
| APPL NO | 16/995338 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 69/44 (20130101) Original (OR) Class C07C 69/602 (20130101) Compositions of Macromolecular Compounds C08L 77/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459299 | Cooks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Robert Graham Cooks (West Lafayette, Indiana); Christopher Pulliam (West Lafayette, Indiana); Ryan M. Bain (West Lafayette, Indiana) |
| ABSTRACT | The invention generally relates to conducting reactions in Leidenfrost-levitated droplets. |
| FILED | Friday, August 14, 2020 |
| APPL NO | 16/993553 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 45/72 (20130101) C07C 45/72 (20130101) C07C 49/747 (20130101) Heterocyclic Compounds C07D 209/40 (20130101) C07D 213/04 (20130101) Original (OR) Class Steroids C07J 41/0005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459439 | Nash et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California); The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California); The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | Landon D. Nash (Sunnyvale, California); Duncan J. Maitland (College Station, Texas); Nicole Docherty (Trop, Michigan); Thomas S. Wilson (San Leandro, California); Ward Small, IV (Livermore, California); Jason Ortega (Pacifica, California); Pooja Singhal (Redwood City, California) |
| ABSTRACT | An embodiment includes a system comprising: a monolithic shape memory polymer (SMP) foam having first and second states; wherein the SMP foam includes: (a) polyurethane, (b) an inner half portion having inner reticulated cells defined by inner struts, (c) an outer half portion, having outer reticulated cells defined by outer struts, surrounding the inner portion in a plane that provides a cross-section of the SMP foam, (d) hydroxyl groups chemically bound to outer surfaces of both the inner and outer struts. Other embodiments are discussed herein. |
| FILED | Tuesday, August 04, 2020 |
| APPL NO | 16/984370 |
| ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 24/0036 (20130101) A61L 24/046 (20130101) A61L 31/06 (20130101) A61L 31/06 (20130101) A61L 31/14 (20130101) A61L 31/146 (20130101) A61L 2400/16 (20130101) A61L 2430/36 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/62 (20130101) B05D 3/144 (20130101) B05D 7/02 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 44/5663 (20130101) B29C 59/14 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2033/04 (20130101) B29K 2069/00 (20130101) B29K 2075/00 (20130101) B29K 2077/00 (20130101) B29K 2995/0093 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/18 (20130101) B32B 27/06 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/36 (20130101) C08J 9/365 (20130101) Original (OR) Class C08J 2201/026 (20130101) C08J 2205/04 (20130101) C08J 2207/10 (20130101) C08J 2375/04 (20130101) Compositions of Macromolecular Compounds C08L 75/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459509 | Magrini et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Kimberly A. Magrini (Golden, Colorado); Braden Hamilton Peterson (Golden, Colorado); Chaiwat Engtrakul (Louisville, Colorado); Andrew Nolan Wilson (Denver, Colorado) |
| ABSTRACT | The present disclosure relates to a device that includes a filter element and a catalyst, where the filter element is configured to remove particulate from a stream that includes at least one of a gas and/or a vapor to form a filtered stream of the gas and/or the vapor, the catalyst is configured to receive the filtered stream and react a compound in the filtered stream to form an upgraded stream of the gas and/or the vapor, further including an upgraded compound, and both the filter element and the catalyst are configured to be substantially stable at temperatures up to about 500° C. |
| FILED | Monday, July 27, 2020 |
| APPL NO | 16/940190 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/8681 (20130101) B01D 2255/20723 (20130101) B01D 2255/20769 (20130101) B01D 2255/20776 (20130101) B01D 2258/02 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 27/19 (20130101) B01J 27/188 (20130101) B01J 27/199 (20130101) Destructive Distillation of Carbonageous Materials for Production of Gas, Coke, Tar, or Similar Materials C10B 53/02 (20130101) C10B 57/18 (20130101) Original (OR) Class Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 3/48 (20130101) C10G 2300/70 (20130101) C10G 2300/1014 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459578 | Sayre et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NMC, INC. (Los Alamos, New Mexico) |
| ASSIGNEE(S) | NMC, INC. (Los Alamos, New Mexico) |
| INVENTOR(S) | Richard Thomas Sayre (Los Alamos, New Mexico); Somya S. Subramanian (Los Alamos, New Mexico); Natalia Friedland (Palo Alto, California) |
| ABSTRACT | Provided are heterologous nucleic acid constructs, vectors and methods for elevating cyclic electron transfer activity, improving carbon concentration, and enhancing carbon fixation in C3 and C4 plants, and algae, and producing biomass or other products from C3 or C4 plants, and algae, selected from among, for example, starches, oils, fatty acids, lipids, cellulose or other carbohydrates, alcohols, sugars, nutraceuticals, pharmaceuticals, fragrance and flavoring compounds, and organic acids, as well as transgenic plants produced thereby. These methods and transgenic plants and algae encompass the expression, or overexpression, of various combinations of genes that improve carbon concentrating systems in plants and algae, such as bicarbonate transport proteins, carbonic anhydrase, light driven proton pump, cyclic electron flow regulators, etc. |
| FILED | Tuesday, May 11, 2021 |
| APPL NO | 17/317362 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/12 (20130101) C12N 15/8261 (20130101) C12N 15/8269 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 1/00 (20130101) Technologies for Adaptation to Climate Change Y02A 40/146 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459585 | Church et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | George M. Church (Brookline, Massachusetts); James Dicarlo (Boston, Massachusetts) |
| ABSTRACT | Methods of multiplex genome engineering in cells using Cas9 is provided which includes a cycle of steps of introducing into the cell a first foreign nucleic acid encoding one or more RNAs complementary to the target DNA and which guide the enzyme to the target DNA, wherein the one or more RNAs and the enzyme are members of a co-localization complex for the target DNA, and introducing into the cell a second foreign nucleic acid encoding one or more donor nucleic acid sequences, and wherein the cycle is repeated a desired number of times to multiplex DNA engineering in cells. |
| FILED | Tuesday, July 08, 2014 |
| APPL NO | 14/903719 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/902 (20130101) Original (OR) Class C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459626 | Green et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | AMERICAN IRON AND STEEL INSTITUTE (Washington, District of Columbia) |
| ASSIGNEE(S) | American Iron and Steel Institute (Washington, District of Columbia) |
| INVENTOR(S) | Edward Green (Sewickley, Pennsylvania); Danyang Li (Pittsburgh, Pennsylvania) |
| ABSTRACT | A flash ironmaking drop tube furnace includes a primary reaction section having a refractory, an induction coil around the refractory, insulation located between the refractory and the induction coil, and a susceptor located inside the refractory, the susceptor being formed of a material that is heated by induction when electrical current flows through the induction coil, and having at least one interior channel through which particles can pass. The furnace further includes a muffle, located below the primary reaction section; an outer shell surrounding the muffle; at least one heater located adjacent to the muffle; insulation located between the at least one heater and the outer shell; at least one particle feeder that feeds a predetermined volume of particles into the furnace above the primary reaction section; and an inlet port for injecting gas into the furnace, the inlet port being located so that the gas flows through the susceptor and muffle in parallel with the particles. |
| FILED | Monday, April 15, 2019 |
| APPL NO | 16/384015 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Manufacture of Iron or Steel C21B 13/0026 (20130101) Original (OR) Class C21B 2100/66 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459658 | Freiderich et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | John W. Freiderich (Oak Ridge, Tennessee); Tasha L. Boyd (Clinton, Tennessee) |
| ABSTRACT | Methods for electropolishing and coating aluminum on a surface of an air and/or moisture sensitive substrate, including: in a vessel, submerging the substrate in a first molten salt bath and applying an anodizing current to the substrate at a first temperature to electropolish the surface of the substrate; wherein the first molten salt bath includes one of a first organic salt bath and first inorganic salt bath; wherein, when used, the first organic salt bath includes one of (a) aluminum halide and ionic liquid, (b) a combination of an aluminum halide and halogenatedmethylphenylsulfone (C6(H5-y,Xy)SO2CX3, where y is a number from 0-5), (c) a combination of an aluminum halide, an ionic liquid, and halogenatedmethylphenylsulfone (C6(H5-y,Xy)SO2CX3), and (d) AlF3-organofluoride-hydrofluoric acid adduct; wherein, when used, the first inorganic salt bath includes aluminum halide and alkali metal halide; and wherein the anodizing current is 10-30 mA/cm2. |
| FILED | Monday, July 19, 2021 |
| APPL NO | 17/379395 |
| ART UNIT | 1759 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 18/31 (20130101) C23C 18/1848 (20130101) Original (OR) Class Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 3/44 (20130101) C25D 3/665 (20130101) Processes for the Electrolytic Removal of Materials From Objects; Apparatus Therefor C25F 3/16 (20130101) C25F 3/22 (20130101) C25F 3/26 (20130101) C25F 3/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459664 | Strongin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Temple University-Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Temple University Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Daniel R. Strongin (Wynnewood, Pennsylvania); Akila C. Thenuwara (Philadelphia, Pennsylvania) |
| ABSTRACT | Novel multi-metal catalysts comprising abundant Earth metals are described herein. Devices comprising the catalysts of the invention are also described. Methods of producing the catalysts are also described herein. Methods of producing hydrogen using the catalysts of the invention are also described herein. |
| FILED | Friday, July 20, 2018 |
| APPL NO | 16/632602 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 27/19 (20130101) B01J 37/0225 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 1/50 (20210101) C25B 11/052 (20210101) C25B 11/061 (20210101) C25B 11/075 (20210101) Original (OR) Class Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 9/08 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/022425 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/90 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459967 | Yun et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan) |
| ASSIGNEE(S) | GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan) |
| INVENTOR(S) | Hanho Yun (Oakland Township, Michigan); Jun-mo Kang (Ann Arbor, Michigan) |
| ABSTRACT | A combustion mode module is configured to switch operation of a low-temperature combustion (LTC) engine between a spark ignition (SI) mode, a positive valve overlap (PVO) mode, and a negative valve overlap (NVO) mode. A spark control module is configured to control a spark plug to generate a spark in a cylinder of the LTC engine when the LTC engine is operating in the SI mode. A valve control module is configured to control intake and exhaust valves of the cylinder to yield a PVO and a NVO when the LTC engine is operating in the PVO mode and the NVO mode, respectively. An air/fuel (A/F) control module is configured to adjust a desired A/F ratio of the LTC engine to a rich A/F ratio when operation of the LTC engine is switched to the PVO mode from either one of the SI mode and the NVO mode. |
| FILED | Tuesday, February 16, 2021 |
| APPL NO | 17/176277 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Controlling Combustion Engines F02D 13/0261 (20130101) F02D 41/0002 (20130101) F02D 41/403 (20130101) F02D 41/1475 (20130101) Original (OR) Class F02D 41/3035 (20130101) F02D 2041/002 (20130101) F02D 2200/08 (20130101) F02D 2200/101 (20130101) F02D 2200/0406 (20130101) Ignition, Other Than Compression Ignition, for Internal-combustion Engines; Testing of Ignition Timing in Compression-ignition Engines F02P 5/145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459977 | Kelleher et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cummins Inc. (Columbus, Indiana) |
| ASSIGNEE(S) | CUMMINS INC. (Columbus, Indiana); SCANIA CV AB (Södertälje, Sweden) |
| INVENTOR(S) | Jordan E. Kelleher (Columbus, Indiana); Lyle E. Kocher (Whiteland, Indiana); Dwight A. Doig (Columbus, Indiana); Brett A. Boas (Columbus, Indiana) |
| ABSTRACT | The present disclosure provides a piston, comprising: a skirt having an upper body portion; and a crown formed on the upper body portion by an additive manufacturing process, the crown including at least one air gap formed and positioned to reduce heat transfer from combustion to at least one cooling gallery formed in the piston. |
| FILED | Wednesday, August 18, 2021 |
| APPL NO | 17/405504 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 5/008 (20130101) B22F 10/20 (20210101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 40/20 (20200101) B33Y 80/00 (20141201) Cylinders, Pistons or Casings, for Combustion Engines; Arrangements of Sealings in Combustion Engines F02F 3/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11460059 | Joshi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Vineet V. Joshi (Richland, Washington); Sina Shahrezaei (Richland, Washington); Curt A. Lavender (Richland, Washington); Rob J. Seffens (Kennewick, Washington); Mark A. Rhodes (Kennewick, Washington); Darrell R. Herling (Kennewick, Washington); Aashish Rohatgi (Richland, Washington) |
| ABSTRACT | Riveted assemblies are provided that can include: a first component having opposing first and second sidewalls; a second component having opposing third and fourth sidewalls, wherein the second sidewall of the first component abuts the third sidewall of the second component to bind and form an affixing interface comprising the second and third sidewall between the first component to the second component; and a rivet extending between a head along a shank to an end, the rivet piercing the first sidewall with the end of the rivet being between the first and fourth sidewalls. Methods for affixing at least two components using a rivet are also provided. The methods can include: providing a first component having opposing first and second sidewalls; providing a second component having opposing third and fourth sidewalls; abutting the second sidewall of the first component to the third sidewall of the second component; providing a rivet extending between a head along a shank to an end; projecting the rivet through at least the first sidewall of the first component to form an affixing interface comprising the second and third sidewalls. |
| FILED | Friday, March 05, 2021 |
| APPL NO | 17/193669 |
| ART UNIT | 3677 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Forging; Hammering; Pressing Metal; Riveting; Forge Furnaces B21J 15/025 (20130101) Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 5/04 (20130101) Original (OR) Class F16B 19/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11460191 | Berry et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Jonathan Dwight Berry (Simpsonville, South Carolina); Michael John Hughes (State College, Pennsylvania) |
| ABSTRACT | Integrated combustor nozzles and turbomachines are provided. An integrated combustor nozzle includes a cooling insert having a flange. The cooling insert further includes a first wall and a second wall that each define respective passages therein. The first wall and the second wall each extend from an open end defined within the flange to a closed end. The first wall and the second wall each include an impingement side spaced apart from a solid side. Each impingement side defines a plurality of impingement apertures configured to direct coolant from the respective passage towards a side wall of the combustion liner. The cooling inserts further includes a collection passageway that is defined between the solid sides of the first wall and the second wall. |
| FILED | Monday, August 31, 2020 |
| APPL NO | 17/007076 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/06 (20130101) Original (OR) Class F23R 3/26 (20130101) F23R 2900/03044 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11460344 | Armijo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Kenneth M. Armijo (Albuquerque, New Mexico); Julius Yellowhair (Albuquerque, New Mexico); Richard K. Harrison (Albuquerque, New Mexico) |
| ABSTRACT | A non-tracking solar sensor device and systems. The non-tracking solar sensor system includes a transparent hemispherical dome enclosure for receiving light. A diffuser is disposed with the enclosure for diffusing the light. A photodiode sensor array senses at least one discrete wavelength of the diffused light. A data acquisition module is configured to receive a sensor signal from the sensor array, the signal indicative of light quality at least one discrete wave band for processing via a processor module. |
| FILED | Thursday, July 23, 2020 |
| APPL NO | 16/936553 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/021 (20130101) G01J 3/51 (20130101) Original (OR) Class G01J 3/0202 (20130101) G01J 3/0208 (20130101) G01J 2003/1221 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11460351 | Skifton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Richard S. Skifton (Idaho Falls, Idaho); Joshua Daw (Idaho Falls, Idaho) |
| ABSTRACT | A coaxial thermocouple includes a wire, an insulation layer surrounding the wire, a sheath surrounding the insulation layer, and an electrical junction formed between the wire and the sheath and at one longitudinal end of the coaxial thermocouple, the electrical junction including a swaged end with an outer diameter of the sheath reducing in diameter along a longitudinal length of the coaxial thermocouple until the sheath contacts the wire within the insulation layer. The wire includes a first material and the sheath includes a second material where the first material includes one of molybdenum (Mo) or niobium (Nb) and the second material includes the other of molybdenum (Mo) or niobium (Nb). |
| FILED | Thursday, November 21, 2019 |
| APPL NO | 16/690630 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 7/06 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11460356 | Berkland et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNIVERSITY OF KANSAS (Lawrence, Kansas) |
| ASSIGNEE(S) | The University of Kansas (Lawrence, Kansas) |
| INVENTOR(S) | Cory Berkland (Wildwood, Missouri); Jonathan Whitlow (Hutchinson, Kansas); Jean Salash (Overland Park, Kansas) |
| ABSTRACT | Disclosed are functional materials for use in additive manufacturing (AM). The functional material can comprise an elastomeric composition (e.g., a silicone composite) for use in, for example, direct ink writing. The elastomeric composition can include and elastomeric resin, and a magnetic nanorod filler dispersed within the elastomeric resin. Nanorod characteristics (e.g., length, diameter, aspect ratio) can be selected to create 3D-printed constructs with desired mechanical properties along different axes. Furthermore, since nickel nanorods are ferromagnetic, the spatial distribution and orientation of nanorods within the continuous phase can be controlled with an external magnetic field. This level of control over the nanostructure of the material system offers another degree of freedom in the design of functional parts and components with anisotropic properties. Magnetic fields can be used to remotely sense compression of the constructs, or alternatively, control the stiffness of these materials. |
| FILED | Monday, June 08, 2020 |
| APPL NO | 16/895965 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/118 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2083/00 (20130101) B29K 2105/162 (20130101) B29K 2509/08 (20130101) B29K 2995/0008 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/037 (20130101) C09D 11/102 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/12 (20130101) Original (OR) Class Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/032 (20130101) H01F 7/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11460466 | Husain et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | JLabs, Co. (Arlington, Virginia) |
| ASSIGNEE(S) | JLabs, Co. (McLean, Virginia) |
| INVENTOR(S) | Jamil Husain (Arlington, Virginia); Jeffrey Dawson (Arlington, Virginia); David White (Arlington, Virginia) |
| ABSTRACT | Described herein are rapid breath testing devices, systems and methods. The device may include a mouthpiece operable to receive air flow from a breath; and a cassette comprising a biosensor and a cassette conduit, the cassette removably connected to the mouthpiece such that at least a sample of the air flow passes through the cassette conduit and over the biosensor. The biosensor may include a plurality of graphene-based sensors and may be operable to detect at least one volatile organic compound in the air flow sample. |
| FILED | Friday, December 17, 2021 |
| APPL NO | 17/644896 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/05 (20130101) A61B 5/095 (20130101) A61B 5/097 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 2200/04 (20130101) B01L 2200/10 (20130101) B01L 2200/027 (20130101) B01L 2300/0645 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 40/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/22 (20130101) G01N 33/497 (20130101) G01N 33/5302 (20130101) Original (OR) Class G01N 33/54346 (20130101) G01N 33/54388 (20210801) G01N 2001/2244 (20130101) G01N 2033/4975 (20130101) G01N 2800/56 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11460620 | Chen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Hou-Tong Chen (Los Alamos, New Mexico) |
| ABSTRACT | Metasurface polarization convertors permit conversion of an input linear polarization to right- or left-handed circular polarization based on the orientation of the input linear polarization, over a broad bandwidth and with high efficiency. The reflected circular polarizations can be used to evaluate samples for circular dichroism. A THz time-domain detection provides a time domain terahertz signal that is Fourier transformed to produce a THz circular dichroism spectrum. |
| FILED | Friday, July 05, 2019 |
| APPL NO | 16/504026 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 4/02 (20130101) Optical Elements, Systems, or Apparatus G02B 1/007 (20130101) G02B 5/3041 (20130101) Original (OR) Class Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0136 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11460639 | Allen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Graham S. Allen (Pleasanton, California); Diana C. Chen (Fremont, California); Matthew J. Cook (Brentwood, California); Robert P. Crist (Tracy, California); Derrek R. Drachenberg (Livermore, California); Jay W. Dawson (Livermore, California); Victor V. Khitrov (San Ramon, California); Leily Kiani (Livermore, California); Michael J. Messerly (Danville, California); Paul H. Pax (Livermore, California); Nick Schenkel (Livermore, California) |
| ABSTRACT | An all fiber wavelength selective coupler provides wavelength selective transfer of optical energy between two or more separated waveguides. The coupler includes signal cores that are separated enough that they can be fusion spliced to standard fibers as lead-in and lead-out pigtails. A bridge between the signal cores facilitates transfer of the optical energy through a process of evanescent coupling. In one example, the bridge is formed of a series of graded index cores. |
| FILED | Tuesday, June 18, 2019 |
| APPL NO | 16/445033 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/30 (20130101) G02B 6/29331 (20130101) G02B 6/29332 (20130101) Original (OR) Class G02B 6/29335 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11461477 | Powers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Architecture Technology Corporation (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Architecture Technology Corporation (Minneapolis, Minnesota) |
| INVENTOR(S) | Judson Powers (Ithaca, New York); Robert A. Joyce (Ithaca, New York); Scott Aloisio (Willseyville, New York); Matthew A. Stillerman (Ithaca, New York) |
| ABSTRACT | An example method includes initializing, by an obfuscation computing system, communications with nodes in a distributed computing platform, the nodes including one or more compute nodes and a controller node, and performing at least one of: (a) code-level obfuscation for the distributed computing platform to obfuscate interactions between an external user computing system and the nodes, wherein performing the code-level obfuscation comprises obfuscating data associated with one or more commands provided by the user computing system and sending one or more obfuscated commands to at least one of the nodes in the distributed computing platform; or (b) system-level obfuscation for the distributed computing platform, wherein performing the system-level obfuscation comprises at least one of obfuscating system management tasks that are performed to manage the nodes or obfuscating network traffic data that is exchanged between the nodes. |
| FILED | Thursday, April 02, 2020 |
| APPL NO | 16/838595 |
| ART UNIT | 2498 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/52 (20130101) G06F 21/60 (20130101) G06F 21/602 (20130101) Original (OR) Class G06F 21/6254 (20130101) G06F 2221/2107 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11462688 | Palmstrom et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Axel Finn Palmstrom (Golden, Colorado); Tomas Leijtens (Emerald Hills, California); Joseph Jonathan Berry (Boulder, Colorado); David Todd Moore (Lakewood, Colorado) |
| ABSTRACT | The present disclosure relates to a device that includes a first layer that includes at least one of a semiconducting material, a hole transport material (HTM), and/or an electron transport material (ETM), a second layer, and a third layer that includes a material that is at least one of transparent or conductive, where the second layer is positioned between the first layer and the third layer, the first layer, the second layer, and the third layer are in electrical contact with each other, and the third layer has a first thickness between greater than zero nm and about 100 nm. In some embodiments of the present disclosure, the semiconducting material may include a perovskite. |
| FILED | Friday, September 27, 2019 |
| APPL NO | 16/585843 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0037 (20130101) H01L 51/0043 (20130101) Original (OR) Class H01L 51/0046 (20130101) H01L 51/422 (20130101) H01L 51/4253 (20130101) H01L 51/5056 (20130101) H01L 51/5072 (20130101) H01L 2251/303 (20130101) H01L 2251/558 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11462736 | Dai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Apple Inc. (Cupertino, California) |
| ASSIGNEE(S) | Apple Inc. (Cupertino, California) |
| INVENTOR(S) | Hongli Dai (Los Altos, California); Dapeng Wang (San Jose, California); Huiming Wu (San Jose, California); Fiona Claire Strobridge (San Francisco, California); John David Carter (Lemont, Illinois); Christopher S. Johnson (Naperville, Illinois); Xiaoping Wang (Naperville, Illinois); Hakim H. Iddir (Hoffman Estates, Illinois); Arthur Jeremy Kropf (Westmont, Illinois); Yan Li (Westmont, Illinois); Victor A. Maroni (Naperville, Illinois); Anh D. Vu (Lemont, Illinois); Zhenzhen Yang (Lemont, Illinois); Arturo Gutierrez (Naperville, Illinois); Yanjie Cui (Arlington Heights, Illinois) |
| ABSTRACT | A compound represented by LiaCo(1-x-2y)Mex(M1M2)yOδ, (Formula (I)) wherein Me, is one or more of Li, Mg, Al, Ca, Ti, Zr, V, Cr, Mn, Fe, Ni, Cu, Zn, Ru and Sn, and wherein 0≤x≤0.3, 0<y≤0.4, 0.95≤α≤1.4, and 1.90≤δ≤2.10 is disclosed. Further, particles including such compounds are described. |
| FILED | Wednesday, February 26, 2020 |
| APPL NO | 16/802347 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 45/1228 (20130101) C01G 51/50 (20130101) C01G 53/42 (20130101) C01G 53/50 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/50 (20130101) C01P 2002/54 (20130101) C01P 2002/72 (20130101) C01P 2002/82 (20130101) C01P 2002/86 (20130101) C01P 2002/88 (20130101) C01P 2004/03 (20130101) C01P 2004/84 (20130101) C01P 2006/40 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/131 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) Original (OR) Class H01M 4/1391 (20130101) H01M 10/0525 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11462878 | Pax et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Paul H. Pax (Livermore, California); Diana C. Chen (Fremont, California); Michael J. Messerly (Danville, California) |
| ABSTRACT | An all solid hybrid waveguiding structure provides large mode area, acceptable losses of the desired core mode and very high losses of the undesired next higher order mode in the core. Embodiments of the waveguide include a hybrid of low index barriers providing confinement by total internal reflection, and further include high index rings that support guided modes only at effective indices different from that of the desired core mode. |
| FILED | Friday, May 22, 2020 |
| APPL NO | 16/881388 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/02395 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/06716 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11462929 | Qi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| INVENTOR(S) | Yanbo Qi (Seattle, Washington); Suryanarayana Kolluri (Seattle, Washington); Venkat Subramanian (Seattle, Washington); Sung-Yuan Chen (Seattle, Washington); Neal Dawson-Elli (Seattle, Washington) |
| ABSTRACT | Electrochemical models for the lithium-ion battery are useful in predicting and controlling its performance. The values of the parameters in these models are vital to their accuracy. However, not all parameters can be measured precisely, especially when destructive methods are prohibited. In some embodiments of the present disclosure, a parameter estimation approach is used to estimate the open circuit potential of the positive electrode (Up) using piecewise linear approximation together with all the other parameters of a single particle model. Up and 10 more parameters may be estimated from a single discharge curve without knowledge of the electrode chemistry using a technique such as a genetic algorithm. Different case studies were presented for estimating Up with different types of parameters of the battery model. The estimated parameters were then validated by comparing simulations at different discharge rates with experimental data. |
| FILED | Wednesday, October 04, 2017 |
| APPL NO | 15/725192 |
| ART UNIT | 2859 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/382 (20190101) G01R 31/396 (20190101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/139 (20130101) H01M 10/44 (20130101) H01M 10/48 (20130101) H01M 10/425 (20130101) H01M 10/0525 (20130101) H01M 2004/028 (20130101) H01M 2010/4271 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0049 (20200101) H02J 7/00716 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11463007 | Singh |
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| FUNDED BY |
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| APPLICANT(S) | Deere and Company (Moline, Illinois) |
| ASSIGNEE(S) | DEERE and COMPANY (Moline, Illinois) |
| INVENTOR(S) | Brij N. Singh (West Fargo, North Dakota) |
| ABSTRACT | A power supply circuit for converting a first voltage to a second voltage where the first voltage is greater than the second voltage, and a power train having the same, are provided. The power supply circuit may have multiple stages and each stage of the power supply circuit may include a first circuit block configured to provide a start-up power to a second circuit block; a second circuit block configured to generate a Pulse-Width-Modulation (PWM) signal that controls a pulse duration of a transistor; a third circuit block configured to activate or deactivate the transistor based on the PWM signal; a fourth circuit block configured to reset a magnetic flux in a transformer to a zero state when the transistor is deactivated; and a fifth circuit block configured to maintain an output of a stage below a predetermined value by adjusting a voltage across the transformer. |
| FILED | Tuesday, August 11, 2020 |
| APPL NO | 16/990238 |
| ART UNIT | 2839 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/0009 (20210501) H02M 1/0064 (20210501) H02M 3/1584 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11463352 | Ros-Giralt et al. |
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| FUNDED BY |
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| APPLICANT(S) | Reservoir Labs, Inc. (New York, New York) |
| ASSIGNEE(S) | Qualcomm Incorporated (San Diego, California) |
| INVENTOR(S) | Jordi Ros-Giralt (Newport Beach, California); Noah Amsel (New York, New York); Richard A. Lethin (New York, New York) |
| ABSTRACT | A technique is described for quantifying the effect of a perturbation on a property of a network link or flow, and to add a new flow, reroute an existing flow, or to reshape a flow, based on a quantitative estimation of the perturbation. |
| FILED | Friday, August 27, 2021 |
| APPL NO | 17/459387 |
| ART UNIT | 2459 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 45/02 (20130101) H04L 45/22 (20130101) H04L 45/24 (20130101) H04L 45/38 (20130101) Original (OR) Class H04L 47/122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11464102 | Romanenko et al. |
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| FUNDED BY |
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| APPLICANT(S) | Fermi Research Alliance, LLC (Batavia, Illinois) |
| ASSIGNEE(S) | FERMI RESEARCH ALLIANCE, LLC (Batavia, Illinois) |
| INVENTOR(S) | Alexander Romanenko (Batavia, Illinois); Sam Posen (Arlington Heights, Illinois); Anna Grassellino (Batavia, Illinois) |
| ABSTRACT | A system and method for treating a cavity comprises preparing a superconducting radio frequency (SRF) cavity for removal of a dielectric layer from on an inner surface of the SRF cavity, subjecting the SRF cavity to a heat treatment in order to remove the dielectric layer from the inner surface of the SRF cavity, and preventing the development of a new dielectric layer on the inner surface of the SRF cavity by preventing an interaction between the inner surface of the SRF cavity and atmospheric gasses. |
| FILED | Saturday, October 05, 2019 |
| APPL NO | 16/594011 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/24 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 7/06 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 7/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11457835 | Sharma et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Saransh Sharma (Pasadena, California); Mikhail Shapiro (Los Angeles, California); Azita Emami (Pasadena, California) |
| ABSTRACT | An apparatus for producing magnetic field gradients includes (a) a first planar electromagnet coil set configured to produce a first magnetic field gradient with respect to a first axis, (b) a second planar electromagnet coil set configured to produce a second magnetic field gradient with respect to a second axis that is orthogonal to the first axis, (c) a third planar electromagnet coil set configured to produce a third magnetic field gradient with respect to a third axis that is orthogonal to the first and second axes, and (d) a controller configured to selectively provide power to the first, second, and/or third electromagnet coil sets to sequentially produce a localization magnetic field gradient with respect to each of the first, second, and third axes, at least a portion of each localization magnetic field gradient having a monotonically-varying magnetic field magnitude along a respective axis. |
| FILED | Friday, November 13, 2020 |
| APPL NO | 17/097349 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/05 (20130101) A61B 5/073 (20130101) Original (OR) Class A61B 5/076 (20130101) A61B 5/6861 (20130101) A61B 2562/0223 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 7/31 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/022 (20130101) G01R 33/385 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11457890 | Song et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Pengfei Song (Rochester, Minnesota); Armando Manduca (Rochester, Minnesota); Shigao Chen (Rochester, Minnesota); Joshua Trzasko (Rochester, Minnesota) |
| ABSTRACT | Described here are systems and methods for imaging blood flow in a subject's vasculature, which may include small blood vessels, using ultrasound without the need for a contrast agent. A locally implemented low-rank matrix decomposition is used together with adaptive cutoff values to provide noninvasive ultrasound blood flow imaging capable of imaging the subject's vasculature with very high spatial and temporal resolution, and without the administration of contrast agents such as microbubble contrast agents. Thus, in some instances the systems and methods can be used to image blood flow in small vessels and tissue microvasculature with high spatial and temporal resolution. |
| FILED | Thursday, February 02, 2017 |
| APPL NO | 16/079289 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/026 (20130101) A61B 8/06 (20130101) Original (OR) Class A61B 8/0891 (20130101) A61B 8/5207 (20130101) A61B 8/5269 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/00 (20130101) G01S 7/52047 (20130101) G01S 7/52077 (20130101) G01S 15/8977 (20130101) G01S 15/8981 (20130101) Image Data Processing or Generation, in General G06T 5/001 (20130101) G06T 7/0012 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11458107 | Shea et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); Yoshiko Miura (Fukuoka, Japan); Yu Hoshino (Fukuoka, Japan); Yuri Nishimura (Fukuoka, Japan); Naoto Oku (Shizuoka, Japan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Kenneth J. Shea (Irvine, California); Hiroyuki Koide (Shizuoka, Japan); Yoshiko Miura (Fukuoka, Japan); Yu Hoshino (Fukuoka, Japan); Yuri Nishimura (Fukuoka, Japan); Naoto Oku (Shizuoka, Japan) |
| ABSTRACT | The present invention relates generally to compositions and methods comprising abiotic, synthetic polymers with affinity and specificity to proteins. The synthetic polymers are an improvement over biological agents by providing a simpler, less expensive, and customizable platform for binding to proteins. In one embodiment, the compositions and methods relate to synthetic polymers with affinity and specificity to vascular endothelial growth factor (VEGF). In one embodiment, the compositions are useful for treating diseases and disorders related to the overexpression of VEGF. In one embodiment, the compositions are useful for treating cancer. In one embodiment, the compositions are useful for detecting VEGF levels from biological samples. In one embodiment, the compositions are useful for detecting overexpression of VEGF from biological samples. In one embodiment, the compositions are used to diagnose cancer. |
| FILED | Friday, August 25, 2017 |
| APPL NO | 16/327898 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/5146 (20130101) Original (OR) Class A61K 31/704 (20130101) A61K 31/785 (20130101) A61K 31/795 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11458221 | Kong et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Hyunjoon Kong (Champaign, Illinois); Yongbeom Seo (Woodbury, Minnesota); Jiayu Leong (Singapore, Singapore); Yu-Heng Deng (Urbana, Illinois) |
| ABSTRACT | Diatom microbubblers comprising diatom biosilica or other silica linked to a catalyst for the decomposition of hydrogen peroxide, such as manganese oxide (MnO2), platinum (Pt), CuO (copper II oxide), or zinc peroxide (ZnO2) particles or nanosheets, or catalase are provided. Further provided are methods of reducing or eliminating biofilm or biofouling conditions. |
| FILED | Wednesday, August 14, 2019 |
| APPL NO | 16/540291 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/26 (20130101) A61L 2/186 (20130101) Original (OR) Class Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/08 (20130101) B01J 23/34 (20130101) B01J 35/02 (20130101) B01J 35/0006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11458230 | Bettinger et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Christopher J. Bettinger (Palo Alto, California); Joost P. Bruggeman (Schorl, Netherlands); Lino Da Silva Ferreira (Cambridge, Massachusetts); Jeffrey M. Karp (Chestnut Hill, Massachusetts); Robert S. Langer (Newton, Massachusetts); Christiaan Nijst (Amsterdam, Netherlands); Andreas Zumbuehl (Nyon, Switzerland); Jason Burdick (Philadelphia, Pennsylvania); Sonia J. Kim (West Nyack, New York) |
| ABSTRACT | The present inventions in various aspects provide elastic biodegradable polymers. In various embodiments, the polymers are formed by the reaction of a multifunctional alcohol or ether and a difunctional or higher order acid to form a pre-polymer, which is cross-linked to form the elastic biodegradable polymer. In preferred embodiments, the cross-linking is performed by functionalization of one or more OR groups on the pre-polymer backbone with vinyl, followed by photopolymerization to form the elastic biodegradable polymer composition or material. Preferably, acrylate is used to add one or more vinyls to the backbone of the pre-polymer to form an acrylated pre-polymer. In various embodiments, acrylated pre-polymers are co-polymerized with one or more acrylated co-polymers. |
| FILED | Friday, November 13, 2020 |
| APPL NO | 17/097901 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) A61K 35/48 (20130101) A61K 45/06 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/38 (20130101) A61L 27/58 (20130101) A61L 31/06 (20130101) Original (OR) Class A61L 31/148 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/6854 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/24 (20130101) C08J 3/246 (20130101) C08J 2367/00 (20130101) C08J 2367/07 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/0025 (20130101) C08K 5/0025 (20130101) Compositions of Macromolecular Compounds C08L 67/00 (20130101) C08L 67/07 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 11/087 (20200101) C12N 11/096 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11458718 | Wardle et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Brian L. Wardle (Lexington, Massachusetts); Anastasios John Hart (Waban, Massachusetts); Enrique J. Garcia (Saragossa, Spain); Alexander H. Slocum (Bow, New Hampshire) |
| ABSTRACT | The present invention provides methods for uniform growth of nanostructures such as nanotubes (e.g., carbon nanotubes) on the surface of a substrate, wherein the long axes of the nanostructures may be substantially aligned. The nanostructures may be further processed for use in various applications, such as composite materials. For example, a set of aligned nanostructures may be formed and transferred, either in bulk or to another surface, to another material to enhance the properties of the material. In some cases, the nanostructures may enhance the mechanical properties of a material, for example, providing mechanical reinforcement at an interface between two materials or plies. In some cases, the nanostructures may enhance thermal and/or electronic properties of a material. The present invention also provides systems and methods for growth of nanostructures, including batch processes and continuous processes. |
| FILED | Monday, February 01, 2021 |
| APPL NO | 17/163936 |
| ART UNIT | 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 37/02 (20130101) Original (OR) Class Nanostructures Formed by Manipulation of Individual Atoms, Molecules, or Limited Collections of Atoms or Molecules as Discrete Units; Manufacture or Treatment Thereof B82B 1/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/18 (20170801) C01B 32/162 (20170801) C01B 2202/08 (20130101) C01B 2202/36 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/005 (20130101) C08J 2363/00 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 9/127 (20130101) D01F 9/133 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/582 (20151101) Technical Subjects Covered by Former US Classification Y10T 156/10 (20150115) Y10T 428/24 (20150115) Y10T 428/269 (20150115) Y10T 428/292 (20150115) Y10T 428/2933 (20150115) Y10T 428/24994 (20150401) Y10T 428/24995 (20150401) Y10T 428/249942 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459299 | Cooks et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Robert Graham Cooks (West Lafayette, Indiana); Christopher Pulliam (West Lafayette, Indiana); Ryan M. Bain (West Lafayette, Indiana) |
| ABSTRACT | The invention generally relates to conducting reactions in Leidenfrost-levitated droplets. |
| FILED | Friday, August 14, 2020 |
| APPL NO | 16/993553 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 45/72 (20130101) C07C 45/72 (20130101) C07C 49/747 (20130101) Heterocyclic Compounds C07D 209/40 (20130101) C07D 213/04 (20130101) Original (OR) Class Steroids C07J 41/0005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459376 | Brown et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Elektrofi, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Elektrofi, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Paul Brown (Boston, Massachusetts); Tyler L. Carter (Newburyport, Massachusetts); Lyndon Fitzgerald Charles, Jr. (Medford, Massachusetts); Chase Spenser Coffman (Newton, Massachusetts); Daniel Benjamin Dadon (East Boston, Massachusetts); Lisa Liu (Somerville, Massachusetts); Sadiqua Shadbar (Allston, Massachusetts); Chaitanya Sudrik (Stoneham, Massachusetts); Yi Tang (Medford, Massachusetts); Shankul Vartak (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure provides compositions and methods for treating a disease or condition in a subject in need thereof, comprising administering to the subject a pharmaceutically effective amount of a composition comprising a plurality of particles comprising at least one therapeutic biologic suspended in a pharmaceutically acceptable liquid carrier. |
| FILED | Friday, June 18, 2021 |
| APPL NO | 17/351963 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Peptides C07K 16/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459473 | Shah et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Ramille N. Shah (Hinsdale, Illinois); Adam E. Jakus (Chicago, Illinois) |
| ABSTRACT | 3D printable ink compositions for forming objects, films and coatings are provided. Also provided are methods of printing the ink compositions and methods for making the ink compositions. The ink compositions include an elastic polymer binder and may have high loadings of solid particles. |
| FILED | Wednesday, January 22, 2020 |
| APPL NO | 16/749062 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/165 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2067/00 (20130101) B29K 2105/16 (20130101) B29K 2505/00 (20130101) B29K 2507/04 (20130101) B29K 2509/02 (20130101) B29K 2511/00 (20130101) B29K 2995/0046 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/03 (20130101) C09D 11/033 (20130101) C09D 11/037 (20130101) C09D 11/104 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459535 | Yeh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Daniel H. Yeh (Tampa, Florida); Ivy Lea Cormier Drexler (St. Petersburg, Florida); Melanie Pickett (Tampa, Florida); David Fulcher (Tampa, Florida) |
| ABSTRACT | In one embodiment, an algae cultivation system includes a basin that contains a liquid and a photobioreactor at least partially immersed in the liquid of the basin, the photobioreactor comprising a closed container including multiple panels that together define an interior space in which algae can be cultivated, at least one of the panels being transparent, the photobioreactor further comprising an inflatable float associated with the container that can be filled with a gas to change one or both of the position and orientation of the container within the liquid. |
| FILED | Monday, November 14, 2016 |
| APPL NO | 15/350657 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/22 (20130101) C12M 23/50 (20130101) Original (OR) Class C12M 29/04 (20130101) C12M 29/20 (20130101) C12M 31/08 (20130101) C12M 41/32 (20130101) C12M 41/40 (20130101) C12M 41/46 (20130101) C12M 41/48 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459552 | Rajan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| INVENTOR(S) | Rakhi Rajan (Norman, Oklahoma) |
| ABSTRACT | Bridge helix-modified variant Cas12a and Cas12b proteins having improved DNA cleavage selectivity in comparison to wild type versions of the Cas12a and Cas12b proteins, nucleic acids encoding the variant proteins, host cells containing the nucleic acids, and methods of their use. |
| FILED | Wednesday, July 01, 2020 |
| APPL NO | 16/946689 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 15/74 (20130101) C12N 15/113 (20130101) C12N 2310/20 (20170501) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459578 | Sayre et al. |
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| FUNDED BY |
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| APPLICANT(S) | NMC, INC. (Los Alamos, New Mexico) |
| ASSIGNEE(S) | NMC, INC. (Los Alamos, New Mexico) |
| INVENTOR(S) | Richard Thomas Sayre (Los Alamos, New Mexico); Somya S. Subramanian (Los Alamos, New Mexico); Natalia Friedland (Palo Alto, California) |
| ABSTRACT | Provided are heterologous nucleic acid constructs, vectors and methods for elevating cyclic electron transfer activity, improving carbon concentration, and enhancing carbon fixation in C3 and C4 plants, and algae, and producing biomass or other products from C3 or C4 plants, and algae, selected from among, for example, starches, oils, fatty acids, lipids, cellulose or other carbohydrates, alcohols, sugars, nutraceuticals, pharmaceuticals, fragrance and flavoring compounds, and organic acids, as well as transgenic plants produced thereby. These methods and transgenic plants and algae encompass the expression, or overexpression, of various combinations of genes that improve carbon concentrating systems in plants and algae, such as bicarbonate transport proteins, carbonic anhydrase, light driven proton pump, cyclic electron flow regulators, etc. |
| FILED | Tuesday, May 11, 2021 |
| APPL NO | 17/317362 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/12 (20130101) C12N 15/8261 (20130101) C12N 15/8269 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 1/00 (20130101) Technologies for Adaptation to Climate Change Y02A 40/146 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459585 | Church et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | George M. Church (Brookline, Massachusetts); James Dicarlo (Boston, Massachusetts) |
| ABSTRACT | Methods of multiplex genome engineering in cells using Cas9 is provided which includes a cycle of steps of introducing into the cell a first foreign nucleic acid encoding one or more RNAs complementary to the target DNA and which guide the enzyme to the target DNA, wherein the one or more RNAs and the enzyme are members of a co-localization complex for the target DNA, and introducing into the cell a second foreign nucleic acid encoding one or more donor nucleic acid sequences, and wherein the cycle is repeated a desired number of times to multiplex DNA engineering in cells. |
| FILED | Tuesday, July 08, 2014 |
| APPL NO | 14/903719 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/902 (20130101) Original (OR) Class C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459586 | Church et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | George M. Church (Brookline, Massachusetts); Susan M. Byrne (Brookline, Massachusetts) |
| ABSTRACT | Inhibiting p53 or Bax can be used to improve nuclease-mediated gene targeting frequencies in stem cells. This inhibition can be achieved, e.g., by overexpression of anti-apoptosis proteins or by silencing or reducing p53 or Bax expression. This technique can be used in conjunction with other rapidly developing CRISPR technologies, including improvements in specificity, other types of nucleases, and further enrichment, screening, and selection schemes, to expand the use of stem cells in experimental studies and tissue engineering for therapeutic purposes. |
| FILED | Wednesday, April 19, 2017 |
| APPL NO | 16/094011 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0606 (20130101) C12N 5/0619 (20130101) C12N 5/0663 (20130101) C12N 5/0696 (20130101) C12N 9/22 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2740/16043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459599 | Doudna et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jennifer A. Doudna (Berkeley, California); Mitchell Ray O'Connell (Oakland, California); Alexandra East-Seletsky (San Francisco, California); Spencer Charles Knight (Berkeley, California); James Harrison Doudna Cate (Berkeley, California) |
| ABSTRACT | The present disclosure provides methods for detecting a single-stranded target RNA. The present disclosure provides methods of cleaving a precursor C2c2 guide RNA array into two or more C2c2 guide RNAs. The present disclosure provides a kit for detecting a target RNA in a sample. |
| FILED | Friday, September 20, 2019 |
| APPL NO | 16/577696 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6823 (20130101) Original (OR) Class C12Q 1/6823 (20130101) C12Q 2521/327 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459600 | Doudna et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jennifer A. Doudna (Berkeley, California); Mitchell Ray O'Connell (Oakland, California); Alexandra East-Seletsky (San Francisco, California); Spencer Charles Knight (Berkeley, California); James Harrison Doudna Cate (Berkeley, California) |
| ABSTRACT | The present disclosure provides methods for detecting a single-stranded target RNA. The present disclosure provides methods of cleaving a precursor C2c2 guide RNA array into two or more C2c2 guide RNAs. The present disclosure provides a kit for detecting a target RNA in a sample. |
| FILED | Friday, September 20, 2019 |
| APPL NO | 16/577740 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6823 (20130101) Original (OR) Class C12Q 1/6823 (20130101) C12Q 2521/327 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459759 | Tolera et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ameyu Tolera (Miami, Florida); Arindam Gan Chowdhury (Miami, Florida); Ioannis Zisis (Miami, Florida) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida) |
| INVENTOR(S) | Ameyu Tolera (Miami, Florida); Arindam Gan Chowdhury (Miami, Florida); Ioannis Zisis (Miami, Florida) |
| ABSTRACT | Roof shingles are provided, as well as methods of fabricating and using the shingles and roofs comprising the shingles. A shingle can include a plurality of perforations in the protruding part thereof to significantly reduce the pressure in the leading edge, the remainder of the protruding part, and/or in the area behind the sealing strip of the shingle. The perforations can be disposed in the protruding part of the shingle down from the sealing strip. Any water entering the perforations can therefore be blocked by the sealing strips and will flow down the roof slope. |
| FILED | Tuesday, May 17, 2022 |
| APPL NO | 17/663708 |
| ART UNIT | 3633 — Static Structures, Supports and Furniture |
| CURRENT CPC | Roof Coverings; Sky-lights; Gutters; Roof-working Tools E04D 1/26 (20130101) E04D 1/29 (20190801) E04D 1/30 (20130101) Original (OR) Class E04D 2001/308 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11460226 | Goldfarbmuren et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rebound Technologies, Inc. (Commerce City, Colorado) |
| ASSIGNEE(S) | Rebound Technologies, Inc. (Commerce City, Colorado) |
| INVENTOR(S) | Russell Goldfarbmuren (Denver, Colorado); Luke Erickson (Denver, Colorado); Josh Nelson (West Lafayette, Indiana) |
| ABSTRACT | Methods, systems, and devices for freeze point suppression cycle control are provided in accordance with various embodiments. For example, some embodiments include a method of freeze point suppression cycle control. The method may include flowing a liquid to a first sensor; the liquid may include a mixture of a melted solid and a freeze point suppressant. The method may include determining an indicator value of a freeze point suppressant property of the liquid utilizing the first sensor. The method may include controlling a flow of the liquid to a separator utilizing a flow controller based on at least the determined indicator value of the freeze point suppressant property of the liquid; the separator may form a concentrated freeze point suppressant from the liquid. Freeze point suppression cycle control systems are also provided. |
| FILED | Sunday, August 23, 2020 |
| APPL NO | 17/000337 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Separation B01D 3/14 (20130101) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 17/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11460395 | Ozcan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Aydogan Ozcan (Los Angeles, California); Aniruddha Ray (Toledo, Ohio); Hyouarm Joung (Los Angeles, California); Derek Tseng (Buena Park, California); Isidro B. Salusky (Los Angeles, California) |
| ABSTRACT | A portable colorimetric assay system includes an opto-mechanical reader configured to be detachably mounted to a mobile phone having a camera or other camera-containing portable electronic device. The opto-mechanical reader includes one or more light sources configured to illuminate a test sample holder and control sample holder disposed in the opto-mechanical reader along an optical path aligned with a camera of the mobile phone or other camera-containing portable electronic device. One or more serum separation membranes are disposed in the opto-mechanical reader and define a sample receiving pad configured to receive a blood sample. A moveable serum collection membrane is membrane is also disposed in the reader and is configured to contact the sample receiving pad in a first position and moveable to a second position where the serum collection membrane is disposed inside the test sample holder. |
| FILED | Friday, June 12, 2020 |
| APPL NO | 16/900838 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5023 (20130101) B01L 3/502753 (20130101) B01L 2300/0681 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/01 (20130101) Original (OR) Class G01N 21/78 (20130101) G01N 21/251 (20130101) G01N 21/8483 (20130101) G01N 33/49 (20130101) G01N 2021/0137 (20130101) G01N 2021/1776 (20130101) G01N 2201/104 (20130101) G01N 2201/0221 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11460685 | Hillman |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trusteees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Elizabeth M. C. Hillman (New York, New York) |
| ABSTRACT | Methods, devices and systems for up to three-dimensional scanning of target regions at high magnification are disclosed. |
| FILED | Wednesday, September 30, 2020 |
| APPL NO | 17/038902 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/0032 (20130101) G02B 21/0052 (20130101) G02B 21/361 (20130101) G02B 21/367 (20130101) Original (OR) Class G02B 23/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11461442 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey); The UAB Research Foundation (Birmingham, Alabama) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey); The UAB Research Foundation (Birmingham, Alabama) |
| INVENTOR(S) | Yingying Chen (Morganville, New Jersey); Jian Liu (Highland Park, New Jersey); Chen Wang (North Bergen, New Jersey); Nitesh Saxena (Hoover, Alabama) |
| ABSTRACT | A user input system comprising a vibration motor, a sensor and a processor in communication with the sensor. The vibration motor is in contact with a surface and generates vibrations in the surface. The vibrations can be altered by a user touching the surface to create altered vibrations. The sensor is in contact with the surface and detects the altered vibrations. The processor receives and analyzes data corresponding to the altered vibrations. The processor determines, based on the analyzed data, whether a user's touch on the surface matches a stored vibration profile of the user. |
| FILED | Wednesday, June 05, 2019 |
| APPL NO | 16/432558 |
| ART UNIT | 2434 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 3/016 (20130101) G06F 3/017 (20130101) G06F 21/316 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11462358 | Lewis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Laura H. Lewis (Boston, Massachusetts); Ian J. McDonald (Weatherly, Pennsylvania); Sahar Keshavarz (Hillsboro, Oregon); R. William McCallum (Santa Fe, New Mexico) |
| ABSTRACT | The invention provides method for making high coercivity magnetic materials based on FeNi alloys having a L10 phase structure, tetratenite, and provides a system for accelerating production of these materials. The FeNi alloy is made by preparing a melt comprising Fe, Ni, and optionally one or more elements selected from the group consisting of Ti, V, Al, B, C, Mo, Ir, and Nb; cooling the melt and applying extensional stress and a magnetic field. This is followed by heating and cooling to form the L10 structure. |
| FILED | Monday, August 20, 2018 |
| APPL NO | 16/639844 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 6/001 (20130101) C21D 8/1233 (20130101) Alloys C22C 33/04 (20130101) C22C 38/08 (20130101) C22C 38/12 (20130101) C22C 2202/02 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/14708 (20130101) H01F 41/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11462402 | Vogt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York); The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York); The Penn State Research Foundation (University Park, Panama) |
| INVENTOR(S) | Patrick Vogt (Ithaca, New York); Darrell G. Schlom (Ithaca, New York); Felix V. E. Hensling (Ithaca, New York); Kathy Azizie (Plainfield, New Jersey); Zi-Kui Liu (State College, Pennsylvania); Brandon J. Bocklund (State College, Pennsylvania); Shun-Li Shang (State College, Pennsylvania) |
| ABSTRACT | Molecular-beam epitaxy (MBE) and more particularly suboxide MBE (S-MBE) and related structures are disclosed. S-MBE is disclosed that includes the use of a molecular beam of a suboxide that may be subsequently oxidized in a single step reaction to form an oxide film. By way of example, for a gallium oxide (Ga2O3) film, a molecular beam including a suboxide of gallium (Ga2O) may be provided. S-MBE may be performed in adsorption-controlled regimes where there is an excess of source material containing species in order to promote high growth rates for oxide films with improved crystallinity. Source mixtures for providing molecular beams of suboxides are disclosed that include mixtures of a particular element and an oxide of the element in ratios that promote such adsorption-controlled growth regimes. Related structures include oxide films having increased thickness with reduced crystal defects, including single polymorph films of gallium oxide. |
| FILED | Wednesday, October 21, 2020 |
| APPL NO | 17/076011 |
| ART UNIT | 2816 — Semiconductors/Memory |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 23/066 (20130101) C30B 29/16 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02565 (20130101) H01L 21/02631 (20130101) Original (OR) Class H01L 29/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11462656 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | Zhiyuan Wang (Lebanon, New Hampshire); Xiaoxin Wang (Hanover, New Hampshire); Jifeng Liu (Hanover, New Hampshire) |
| ABSTRACT | Disclosed are infrared (IR) light detectors. The detectors operate by generating hot electrons in a metallic absorber layer on photon absorption, the electrons being transported through an energy barrier of an insulating layer to a metal or semiconductor conductive layer. The energy barrier is set to bar response to wavelengths longer than a maximum wavelength. Particular embodiments also have a pattern of metallic shapes above the metallic absorber layer that act to increase photon absorption while reflecting photons of short wavelengths; these particular embodiments have a band-pass response. |
| FILED | Friday, April 20, 2018 |
| APPL NO | 16/606829 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/146 (20130101) H01L 27/1446 (20130101) H01L 27/14875 (20130101) H01L 31/119 (20130101) Original (OR) Class H01L 31/02327 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11462682 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Jian-Ping Wang (Shoreview, Minnesota); Thomas Jon Peterson (Lauderdale, Minnesota); Anthony William Hurben (Bloomington, Minnesota); Delin Zhang (Saint Paul, Minnesota) |
| ABSTRACT | A magnetic device may include a layer stack including a work function structure, a dielectric layer, and a ferromagnetic layer, where the ferromagnetic layer is positioned between the work function structure and the dielectric layer. The work function structure is configured to deplete electrons from the ferromagnetic layer or accumulate electrons in the ferromagnetic layer. A magnetization orientation of the ferromagnetic layer is configured to be switched by a voltage applied across the layer stack or by a voltage applied across or through the work function structure. |
| FILED | Friday, February 19, 2021 |
| APPL NO | 17/249105 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/049 (20130101) Static Stores G11C 11/161 (20130101) G11C 11/1673 (20130101) G11C 11/1675 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/222 (20130101) H01L 43/02 (20130101) H01L 43/10 (20130101) Original (OR) Class H01L 43/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11463113 | Medard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (Munich, Germany) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (Munich, Germany) |
| INVENTOR(S) | Muriel Medard (Belmont, Massachusetts); Cornelius Hans Ulrich Hellge (Berlin, Germany) |
| ABSTRACT | Systems and techniques described herein include jointly decoding coded data of different codes, including different coding algorithms, finite fields, and/or source blocks sizes. The techniques described herein can be used to improve existing distributed storage systems by allowing gradual data migration. The techniques can further be used within existing storage clients to allow application data to be stored within diverse different distributed storage systems. |
| FILED | Friday, January 27, 2017 |
| APPL NO | 16/066866 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 13/47 (20130101) H03M 13/158 (20130101) H03M 13/255 (20130101) H03M 13/616 (20130101) H03M 13/1515 (20130101) H03M 13/2903 (20130101) H03M 13/2927 (20130101) H03M 13/3761 (20130101) H03M 13/3769 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 67/1097 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 11458451 | Shaikh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | XPLOSAFE, LLC (Stillwater, Oklahoma) |
| ASSIGNEE(S) | XPLOSAFE, LLC (Stillwater, Oklahoma) |
| INVENTOR(S) | Shoaib F. Shaikh (Stillwater, Oklahoma); Allen W. Apblett (Stillwater, Oklahoma); Nicholas F. Materer (Stillwater, Oklahoma); Evgueni Kadossov (Stillwater, Oklahoma) |
| ABSTRACT | The present invention provides an improved sorbent and corresponding device(s) and uses thereof for the capture and stabilization of volatile organic compounds (VOC) or semi-volatile organic compounds (SVOC) from a gaseous atmosphere. The sorbent is capable of rapid and high uptake of one or more compounds and provides quantitative release (recovery) of the compound(s) when exposed to elevated temperature and/or organic solvent. Uses of particular improved grades of mesoporous silica are disclosed. |
| FILED | Tuesday, December 18, 2018 |
| APPL NO | 16/224049 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/02 (20130101) B01D 2253/106 (20130101) B01D 2257/708 (20130101) B01D 2259/4583 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/103 (20130101) Original (OR) Class B01J 20/3204 (20130101) B01J 20/3219 (20130101) B01J 20/3246 (20130101) B01J 20/3293 (20130101) B01J 20/28021 (20130101) B01J 20/28064 (20130101) B01J 20/28073 (20130101) B01J 20/28076 (20130101) B01J 20/28083 (20130101) Non-metallic Elements; Compounds Thereof; C01B 33/18 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/82 (20130101) C01P 2004/04 (20130101) C01P 2004/13 (20130101) C01P 2006/12 (20130101) C01P 2006/14 (20130101) C01P 2006/16 (20130101) Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 21/0091 (20130101) C06B 23/00 (20130101) C06B 45/00 (20130101) Blasting F42D 5/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11460377 | Farris et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Mitre Corporation (McLean, Virginia) |
| ASSIGNEE(S) | THE MITRE CORPORATION (McLean, Virginia) |
| INVENTOR(S) | Michael Heath Farris (Vienna, Virginia); Kevin Robert Gemp (Falls Church, Virginia); David Masters (Great Falls, Virginia) |
| ABSTRACT | Various embodiments directed to a work stand for holding a microscopic collection device for collecting a microscopic sample from a target surface, are provided. The work stand includes a first slit formed on a top surface of the work stand and capable of holding a first microscopic collection device comprising a first holding element and a first collection platform, wherein the first collection platform of the first microscopic collection device is perpendicular to the top surface. A second slit formed on the top surface of the work stand and capable of holding a second microscopic collection device comprising a second collection platform and a second holding element at an angle to the second collection platform perpendicular to the top surface of the work stand. |
| FILED | Tuesday, March 17, 2020 |
| APPL NO | 16/821335 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/02 (20130101) Original (OR) Class G01N 1/2813 (20130101) G01N 2001/028 (20130101) G01N 2001/2833 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11460435 | Barrall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ELECTRONIC BIOSCIENCES, INC. (San Diego, California) |
| ASSIGNEE(S) | ELECTRONIC BIOSCIENCES, INC. (San Diego, California) |
| INVENTOR(S) | Geoffrey A. Barrall (San Jose, California); Eric N. Ervin (Holladay, Utah); Prithwish Pal (San Diego, California) |
| ABSTRACT | Provided are device components, devices and methods characterized by a high contrast signal to noise ratio (CNR). |
| FILED | Wednesday, January 16, 2019 |
| APPL NO | 16/249312 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/447 (20130101) Original (OR) Class G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11460572 | Pedross-Engel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Andreas Pedross-Engel (Seattle, Washington); Daniel Arnitz (Seattle, Washington); Matthew S. Reynolds (Seattle, Washington) |
| ABSTRACT | Examples of active millimeter-wave imaging systems are described which may utilize modulation schemes to provide illumination signals. The use of modulation techniques may allow for the use of direct-conversion receivers while retaining an ability to separate desired received signal from self-jamming and/or DC offset signal(s) generated by the direct-conversion receivers. In some examples, modulation schemes include the use of balanced orthogonal codes which may support MIMO or massive MIMO imaging systems. |
| FILED | Thursday, August 10, 2017 |
| APPL NO | 16/323491 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/89 (20130101) Original (OR) Class G01S 13/325 (20130101) G01S 13/887 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/20 (20130101) Pictorial Communication, e.g Television H04N 5/2256 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11461450 | Boyd et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Daniel A. Boyd (Arlington, Virginia); Kelli L. Biegger (McLean, Virginia); Chang Ellison (Arlington, Virginia); Brandon P. Gutierrez (Burke, Virginia); Jason Lim (Alexandria, Virginia); William Washington (North Potomac, Maryland) |
| ABSTRACT | An online host method to verify hosted information associated with a user includes establishing, by the online host serving as a relying party system (RPS), a secure connection between the RPS and a user mobile-identification-credential device (UMD). The RPS sends a mobile identification credential (MIC) user information request to the UMD, via the secure connection, seeking release of MIC user information (official information). The RPS obtains from authorizing party system (APS) verification of the MIC user information received in response to the MIC user information request. The RPS stores the MIC user information as hosted information pertaining to the user. The RPS designates the hosted information as base truth information representing the user. |
| FILED | Tuesday, November 30, 2021 |
| APPL NO | 17/538356 |
| ART UNIT | 2493 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/32 (20130101) Original (OR) Class G06F 2221/2133 (20130101) Image or Video Recognition or Understanding G06V 10/40 (20220101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0825 (20130101) H04L 9/3213 (20130101) H04L 9/3247 (20130101) H04L 63/0823 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11459130 | Mata et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Marianne E. Mata (Chicago, Illinois); Martin E. Lozano (Chicago, Illinois); Tyler C. Staudinger (Chicago, Illinois); John H. Blumer (Chicago, Illinois); Mark W. Henley (Chicago, Illinois) |
| ABSTRACT | A fuel cell-based power system comprises a fuel cell configured for continuously receiving a first reactant and a second reactant to produce chemical reactions that generate electrical power, water, and heat, a coolant subsystem configured for circulating a primary coolant in association with the fuel cell, thereby absorbing the generated heat, a tank configured for storing a reactant, and a reactant distribution subsystem configured for conveying the reactant from the tank to an independent system, the fuel cell as the first reactant, and the coolant subsystem as a secondary coolant to remove the absorbed heat from the primary coolant and/or a water accumulator. The secondary coolant may be conveyed to a gas thruster as a gas after the absorbed heat has been removed from the secondary coolant. The reactant may boil off of a cryogenic liquid or vapor or gas transformed from a cryogenic liquid via a heater. |
| FILED | Wednesday, December 04, 2019 |
| APPL NO | 16/703747 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/24 (20130101) Cosmonautics; Vehicles or Equipment Therefor B64G 1/42 (20130101) Original (OR) Class B64G 1/402 (20130101) B64G 1/423 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/04014 (20130101) H01M 8/04208 (20130101) H01M 8/04701 (20130101) H01M 2250/20 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/40 (20130101) Y02T 50/60 (20130101) Y02T 90/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11460841 | Thakur et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nissan North America, Inc. (Franklin, Tennessee); United States of America as Represented by the Administrator of NASA (Washington, District of Columbia); Renault S.A.S. (Boulogne-Billancourt, France) |
| ASSIGNEE(S) | Nissan North America, Inc. (Franklin, Tennessee); United States of America as Represented by the Administrator of NASA (Washington, District of Columbia); Renault S.A.S. (Boulogne-Billancourt, France) |
| INVENTOR(S) | Siddharth Thakur (Paris, France); Armelle Guerin (Woodside, California); Atsuhide Kobashi (Sunnyvale, California); Julius S. Gyorfi (Vernon Hills, Illinois); Mark B. Allan (Campbell, California) |
| ABSTRACT | An apparatus for remote support of autonomous operation of a vehicle includes a processor that is configured to perform a method including receiving, from a vehicle traversing a driving route from a start point to an end point at a destination, an assistance request signal identifying an inability of the vehicle at the destination to reach the end point, generating a first map display including a representation of a geographical area and the vehicle within the geographical area, receiving, from the vehicle, sensor data from one or more sensing devices of the vehicle, generating a remote support interface including the first map display and the sensor data, and transmitting instruction data to the vehicle that includes an alternative end point at the destination responsive to an input signal provided to the remote support interface. |
| FILED | Thursday, February 21, 2019 |
| APPL NO | 16/969080 |
| ART UNIT | 3665 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 50/14 (20130101) B60W 60/001 (20200201) B60W 2050/146 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/3461 (20130101) G01C 21/3815 (20200801) G01C 21/3848 (20200801) Systems for Controlling or Regulating Non-electric Variables G05D 1/0022 (20130101) Original (OR) Class G05D 1/0044 (20130101) Wireless Communication Networks H04W 4/024 (20180201) H04W 4/48 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11461912 | Matthies et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Larry H. Matthies (Northridge, California); Cevahir Cigla (Pasadena, California) |
| ABSTRACT | A method and system provide for temporal fusion of depth maps in an image space representation. A series of depth maps are obtained/acquired from one or more depth sensors at a first time. A first Gaussian mixture model (GMM) is initialized using one of the series of depth maps. A second depth map is obtained from the depth sensors at a second time. An estimate of the motion of the depth sensors, from the first time to the second time, is received. A predictive GMM at the second time is created based on a transform of the first GMM and the estimate of the motion. The predictive GMM is updated based on the second depth map. |
| FILED | Thursday, July 19, 2018 |
| APPL NO | 16/040006 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 39/028 (20130101) B64C 2201/027 (20130101) B64C 2201/123 (20130101) B64C 2201/127 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 47/08 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6226 (20130101) G06K 9/6289 (20130101) Image Data Processing or Generation, in General G06T 7/579 (20170101) Original (OR) Class G06T 2207/10021 (20130101) G06T 2207/10028 (20130101) G06T 2207/10032 (20130101) G06T 2207/20076 (20130101) G06T 2207/30261 (20130101) Image or Video Recognition or Understanding G06V 10/751 (20220101) G06V 20/10 (20220101) G06V 20/13 (20220101) G06V 20/64 (20220101) Traffic Control Systems G08G 5/045 (20130101) G08G 5/0069 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11462402 | Vogt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cornell University (Ithaca, New York); The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York); The Penn State Research Foundation (University Park, Panama) |
| INVENTOR(S) | Patrick Vogt (Ithaca, New York); Darrell G. Schlom (Ithaca, New York); Felix V. E. Hensling (Ithaca, New York); Kathy Azizie (Plainfield, New Jersey); Zi-Kui Liu (State College, Pennsylvania); Brandon J. Bocklund (State College, Pennsylvania); Shun-Li Shang (State College, Pennsylvania) |
| ABSTRACT | Molecular-beam epitaxy (MBE) and more particularly suboxide MBE (S-MBE) and related structures are disclosed. S-MBE is disclosed that includes the use of a molecular beam of a suboxide that may be subsequently oxidized in a single step reaction to form an oxide film. By way of example, for a gallium oxide (Ga2O3) film, a molecular beam including a suboxide of gallium (Ga2O) may be provided. S-MBE may be performed in adsorption-controlled regimes where there is an excess of source material containing species in order to promote high growth rates for oxide films with improved crystallinity. Source mixtures for providing molecular beams of suboxides are disclosed that include mixtures of a particular element and an oxide of the element in ratios that promote such adsorption-controlled growth regimes. Related structures include oxide films having increased thickness with reduced crystal defects, including single polymorph films of gallium oxide. |
| FILED | Wednesday, October 21, 2020 |
| APPL NO | 17/076011 |
| ART UNIT | 2816 — Semiconductors/Memory |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 23/066 (20130101) C30B 29/16 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02565 (20130101) H01L 21/02631 (20130101) Original (OR) Class H01L 29/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11458451 | Shaikh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | XPLOSAFE, LLC (Stillwater, Oklahoma) |
| ASSIGNEE(S) | XPLOSAFE, LLC (Stillwater, Oklahoma) |
| INVENTOR(S) | Shoaib F. Shaikh (Stillwater, Oklahoma); Allen W. Apblett (Stillwater, Oklahoma); Nicholas F. Materer (Stillwater, Oklahoma); Evgueni Kadossov (Stillwater, Oklahoma) |
| ABSTRACT | The present invention provides an improved sorbent and corresponding device(s) and uses thereof for the capture and stabilization of volatile organic compounds (VOC) or semi-volatile organic compounds (SVOC) from a gaseous atmosphere. The sorbent is capable of rapid and high uptake of one or more compounds and provides quantitative release (recovery) of the compound(s) when exposed to elevated temperature and/or organic solvent. Uses of particular improved grades of mesoporous silica are disclosed. |
| FILED | Tuesday, December 18, 2018 |
| APPL NO | 16/224049 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/02 (20130101) B01D 2253/106 (20130101) B01D 2257/708 (20130101) B01D 2259/4583 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/103 (20130101) Original (OR) Class B01J 20/3204 (20130101) B01J 20/3219 (20130101) B01J 20/3246 (20130101) B01J 20/3293 (20130101) B01J 20/28021 (20130101) B01J 20/28064 (20130101) B01J 20/28073 (20130101) B01J 20/28076 (20130101) B01J 20/28083 (20130101) Non-metallic Elements; Compounds Thereof; C01B 33/18 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/82 (20130101) C01P 2004/04 (20130101) C01P 2004/13 (20130101) C01P 2006/12 (20130101) C01P 2006/14 (20130101) C01P 2006/16 (20130101) Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 21/0091 (20130101) C06B 23/00 (20130101) C06B 45/00 (20130101) Blasting F42D 5/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11459624 | Petropoulos |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MONOGRAM BIOSCIENCES, INC. (South San Francisco, California) |
| ASSIGNEE(S) | Monogram Biosciences, Inc. (South San Francisco, California) |
| INVENTOR(S) | Christos J. Petropoulos (Half Moon Bay, California) |
| ABSTRACT | The invention provides a method for determining whether a human immunodeficiency virus is resistant to a viral entry inhibitor. The methods are particularly useful for determining resistance to inhibitors that act by a non-competitive mechanism. In certain aspects, the methods comprise determining whether an HIV population is resistant to an HIV entry inhibitor, comprising determining a log-sigmoid inhibition curve comprising data points for entry of the HIV population in the presence of varying concentrations of the HIV entry inhibitor, wherein if the entry of the HIV population cannot be completely inhibited by the HIV entry inhibitor, the HIV population is resistant to the HIV entry inhibitor. |
| FILED | Monday, February 03, 2020 |
| APPL NO | 16/780426 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/16021 (20130101) C12N 2740/16062 (20130101) C12N 2740/16122 (20130101) C12N 2770/20021 (20130101) C12N 2800/40 (20130101) C12N 2800/107 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/04 (20130101) C12Q 1/66 (20130101) C12Q 1/70 (20130101) C12Q 1/703 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101) G01N 2333/16 (20130101) G01N 2333/162 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11463231 | Chornenky |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NOKOMIS, INC. (Canonsburg, Pennsylvania) |
| ASSIGNEE(S) | Nokomis, Inc (Canonsburg, Pennsylvania) |
| INVENTOR(S) | Todd Eric Chornenky (Carmichaels, Pennsylvania) |
| ABSTRACT | An apparatus and method to transmit and receive messages within and near the noise floor by pulsed signals that are time synchronized and are not easily intercepted by use of frequency and time slots as well as intermittent transmissions. |
| FILED | Monday, September 14, 2020 |
| APPL NO | 17/020337 |
| ART UNIT | 2637 — Optical Communications |
| CURRENT CPC | Transmission H04B 1/16 (20130101) H04B 17/336 (20150115) Transmission of Digital Information, e.g Telegraphic Communication H04L 7/0012 (20130101) Original (OR) Class H04L 7/0037 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 11459461 | Hassan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana) |
| ASSIGNEE(S) | Board of Supervisors of Lousiana State University (Baton Rouge, Louisiana) |
| INVENTOR(S) | Marwa Hassan (Baton Rouge, Louisiana); Max Abelardo Aguirre Deras (Baton Rouge, Louisiana) |
| ABSTRACT | Asphalt rejuvenating fibers and asphalt rejuvenation materials for self-healing asphalt applications are provided. The asphalt rejuvenating fibers can include a shell surrounding a hollow space. The shell can include alginate salts, an emulsifier, and a plasticizer. The asphalt rejuvenation materials can include the asphalt rejuvenating, an asphalt binder, and aggregate blends. |
| FILED | Thursday, April 02, 2020 |
| APPL NO | 16/838411 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/0016 (20130101) Compositions of Macromolecular Compounds C08L 5/04 (20130101) C08L 91/00 (20130101) C08L 95/00 (20130101) Original (OR) Class C08L 2555/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11461692 | Jeng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CLR Analytics Inc. (Irvine, California) |
| ASSIGNEE(S) | CLR Analytics Inc. (Irvine, California) |
| INVENTOR(S) | Shin-Ting Jeng (Corona, California); Qi Lin (Irvine, California); Huabing Wang (Pittsburgh, Pennsylvania); Lianyu Chu (Irvine, California) |
| ABSTRACT | Single loop inductive sensors are widely deployed in infrastructure for traffic data collection, however, these loops currently provide little more than vehicle detection. A system and method are provided that enable single loop inductive sensors to be used for vehicle classification (e.g., identification as motorcycle, passenger car, bus, etc.). Classification may be done using the Federal Highway Administration's 13 class system. Initially a signature library is built from vehicle signatures with known classifications. Vehicle signature waveforms of unknown classification obtained from inductive loop sensors are analyzed to identify specific features in the waveform including the number of “peaks”, the first peak location and its magnitude. A classifier (e.g., K-nearest neighbor) uses a representation of the vehicle signature and the features to determine from the signature library the classification of the vehicle. |
| FILED | Tuesday, April 17, 2018 |
| APPL NO | 15/955647 |
| ART UNIT | 2126 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 5/047 (20130101) G06N 20/00 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 11460333 | Foxx-Gruensteidl |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
| INVENTOR(S) | Manfred Foxx-Gruensteidl (Amissville, Virginia) |
| ABSTRACT | A system for processing delivery items, the system including a delivery item monitoring device comprising one or more sensor and a processor that is communicatively connected to the delivery item monitoring device and that is configured to perform operations comprising obtaining sensor data from the one or more sensor. The operations can also include calculating a depth of the received delivery items in the container based on the sensor data and generating an under-filled indicator, a transport indicator, or an over-filled indicator based on the depth of the received delivery items in the container. Furthermore, the operations can include transmitting the under-filled indicator, the transport indicator, or the over-filled indicator to a control system, wherein the under-filled indicator, the transport indicator, and the over-filled indicator designate how to process the container to the control system. |
| FILED | Wednesday, October 28, 2020 |
| APPL NO | 17/082154 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/22 (20130101) Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 17/00 (20130101) Original (OR) Class G01F 25/0092 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11461571 | Simpson |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Ryan J. Simpson (Vienna, Virginia) |
| ABSTRACT | The present disclosure relates to a system for reading a barcode independently of image resolution or scale of a captured barcode image. In one embodiment, the system includes an optical sensor and a processor. The optical scanner can scan a barcode, including a plurality of bars and spaces, into a scanned image. The processor can convert the scanned image into binary data. The processor can also calculate numbers of ones (1s) between zeros (0s) in the binary data and determine widths of one of i) each of the bars and ii) each of the spaces based on the calculated numbers of ones (1s). The processor can further calculate numbers of zeros (0s) between ones (1s) in the binary data and determine widths of the other one of i) each of the bars and ii) each of the spaces based on the calculated numbers of zeros (0s). |
| FILED | Friday, February 12, 2021 |
| APPL NO | 17/174736 |
| ART UNIT | 2887 — Optics |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/1413 (20130101) G06K 7/10722 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11463971 | Hollar |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wiser Systems, Inc. (Raleigh, North Carolina) |
| ASSIGNEE(S) | Wiser Systems, Inc. (Raleigh, North Carolina) |
| INVENTOR(S) | Seth Edward-Austin Hollar (Raleigh, North Carolina) |
| ABSTRACT | Methods for determining a location of an unknown device (UD) from a plurality of known devices (KDs) are provided including receiving, at the UD, periodically broadcasted messages from each of a plurality of KDs. Corresponding arrival time stamp (Tarrival-i-UD) of each periodically broadcasted message from each of the plurality of KDs are recorded. Each of the plurality of KDs are clock synchronized to a common clock source at a master device (MD). A departure time of the periodically broadcasted message from each of the plurality of KDs is known by the UD in master device time units (Tdepart-i-md). X, y and z coordinates of a location of each of the KDs is known by the UD. The x, y and z coordinates of an actual location of the UD is calculated using the x, y and z coordinates of each of the KDs, the recorded arrival times (Tarrival-i-UD) of each of the periodically broadcasted messages from each of the plurality of KDs and the known departure times of each of the periodically broadcasted messages (Tdepart-i-md) from each of the plurality of KDs. |
| FILED | Thursday, October 24, 2019 |
| APPL NO | 16/662307 |
| ART UNIT | 2414 — Multiplex and VoIP |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/00 (20130101) G01S 5/14 (20130101) G01S 5/021 (20130101) G01S 5/0218 (20200501) G01S 5/0263 (20130101) G01S 11/08 (20130101) Broadcast Communication H04H 20/18 (20130101) Wireless Communication Networks H04W 56/006 (20130101) H04W 56/007 (20130101) H04W 56/0015 (20130101) Original (OR) Class H04W 56/0025 (20130101) H04W 56/0065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 11458451 | Shaikh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | XPLOSAFE, LLC (Stillwater, Oklahoma) |
| ASSIGNEE(S) | XPLOSAFE, LLC (Stillwater, Oklahoma) |
| INVENTOR(S) | Shoaib F. Shaikh (Stillwater, Oklahoma); Allen W. Apblett (Stillwater, Oklahoma); Nicholas F. Materer (Stillwater, Oklahoma); Evgueni Kadossov (Stillwater, Oklahoma) |
| ABSTRACT | The present invention provides an improved sorbent and corresponding device(s) and uses thereof for the capture and stabilization of volatile organic compounds (VOC) or semi-volatile organic compounds (SVOC) from a gaseous atmosphere. The sorbent is capable of rapid and high uptake of one or more compounds and provides quantitative release (recovery) of the compound(s) when exposed to elevated temperature and/or organic solvent. Uses of particular improved grades of mesoporous silica are disclosed. |
| FILED | Tuesday, December 18, 2018 |
| APPL NO | 16/224049 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/02 (20130101) B01D 2253/106 (20130101) B01D 2257/708 (20130101) B01D 2259/4583 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/103 (20130101) Original (OR) Class B01J 20/3204 (20130101) B01J 20/3219 (20130101) B01J 20/3246 (20130101) B01J 20/3293 (20130101) B01J 20/28021 (20130101) B01J 20/28064 (20130101) B01J 20/28073 (20130101) B01J 20/28076 (20130101) B01J 20/28083 (20130101) Non-metallic Elements; Compounds Thereof; C01B 33/18 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/82 (20130101) C01P 2004/04 (20130101) C01P 2004/13 (20130101) C01P 2006/12 (20130101) C01P 2006/14 (20130101) C01P 2006/16 (20130101) Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 21/0091 (20130101) C06B 23/00 (20130101) C06B 45/00 (20130101) Blasting F42D 5/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 11458309 | Zorman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States Government as represented by the United States Department of Veterans Affairs (Washington, District of Columbia); CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia); Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Christian Zorman (Euclid, Ohio); Douglas Shire (Ithaca, New York); David Keicher (Los Ranchos, New Mexico); Katherine M. Bogie (Shaker Heights, Ohio) |
| ABSTRACT | Provided are devices and methods for providing a flexible implantable tissue stimulator. A flexible implantable tissue stimulator can be use in a variety of medical/surgical procedures, and therapeutic interventions, such as musculoskeletal stimulation therapy. The flexible implantable tissue stimulator can be implanted via a minimally invasive procedure and comprises a biocompatible flexible construction that enables it to conform to a variety of implantation orientations and biological conditions. The flexible implantable tissue can provide programmable biphasic electrical stimulation to impaired tissue, such as a gluteal muscle. |
| FILED | Wednesday, September 19, 2018 |
| APPL NO | 16/648031 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/08 (20130101) A61N 1/0509 (20130101) A61N 1/0514 (20130101) A61N 1/3601 (20130101) A61N 1/3611 (20130101) A61N 1/3787 (20130101) A61N 1/36003 (20130101) Original (OR) Class A61N 1/36007 (20130101) A61N 1/36053 (20130101) A61N 1/36071 (20130101) A61N 1/37217 (20130101) A61N 1/37229 (20130101) A61N 1/37252 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Reconnaissance Office (NRO)
| US 11460572 | Pedross-Engel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Andreas Pedross-Engel (Seattle, Washington); Daniel Arnitz (Seattle, Washington); Matthew S. Reynolds (Seattle, Washington) |
| ABSTRACT | Examples of active millimeter-wave imaging systems are described which may utilize modulation schemes to provide illumination signals. The use of modulation techniques may allow for the use of direct-conversion receivers while retaining an ability to separate desired received signal from self-jamming and/or DC offset signal(s) generated by the direct-conversion receivers. In some examples, modulation schemes include the use of balanced orthogonal codes which may support MIMO or massive MIMO imaging systems. |
| FILED | Thursday, August 10, 2017 |
| APPL NO | 16/323491 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/89 (20130101) Original (OR) Class G01S 13/325 (20130101) G01S 13/887 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/20 (20130101) Pictorial Communication, e.g Television H04N 5/2256 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 11463272 | Klenk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NVIDIA Corporation (Santa Clara, California) |
| ASSIGNEE(S) | NVIDIA Corporation (Santa Clara, California) |
| INVENTOR(S) | Benjamin Klenk (San Jose, California); Nan Jiang (Santa Clara, California); Larry Robert Dennison (Menden, Massachusetts); Gregory M. Thorson (Palo Alto, California) |
| ABSTRACT | A network device configured to perform scalable, in-network computations is described. The network device is configured to process pull requests and/or push requests from a plurality of endpoints connected to the network. A collective communication primitive from a particular endpoint can be received at a network device. The collective communication primitive is associated with a multicast region of a shared global address space and is mapped to a plurality of participating endpoints. The network device is configured to perform an in-network computation based on information received from the participating endpoints before forwarding a response to the collective communication primitive back to one or more of the participating endpoints. The endpoints can inject pull requests (e.g., load commands) and/or push requests (e.g., store commands) into the network. A multicast capability enables tasks, such as a reduction operation, to be offloaded to hardware in the network device. |
| FILED | Wednesday, October 06, 2021 |
| APPL NO | 17/495547 |
| ART UNIT | 2448 — Computer Networks |
| CURRENT CPC | Electric Digital Data Processing G06F 9/5083 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 12/18 (20130101) H04L 12/1886 (20130101) Original (OR) Class H04L 45/74 (20130101) H04L 47/20 (20130101) H04L 47/39 (20130101) H04L 47/806 (20130101) H04L 67/55 (20220501) H04L 67/568 (20220501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 11458227 | Elisseeff et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Jennifer H. Elisseeff (Baltimore, Maryland); Kaitlyn Sadtler (Baltimore, Maryland); Drew M. Pardoll (Brookeville, Maryland) |
| ABSTRACT | The present disclosure relates to compositions and methods for modulating wound healing and regeneration. More particularly, the present disclosure relates to immunomodulatory agents that promote wound healing and tissue regeneration, and that may be optionally used in combination with synthetic or biomaterial scaffolds. |
| FILED | Friday, August 05, 2016 |
| APPL NO | 15/750795 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/24 (20130101) A61L 27/54 (20130101) Original (OR) Class A61L 27/3633 (20130101) A61L 2300/25 (20130101) A61L 2300/256 (20130101) A61L 2300/412 (20130101) A61L 2300/426 (20130101) A61L 2430/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 11461372 | Mishra et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Sandeep Mishra (Manchester, New Hampshire); James C. Bode (Amherst, New Hampshire); Michael C. Caron (Merrimack, New Hampshire); Thomas A. Folsom (Bow, New Hampshire); Michael A. Zalucki (Hollis, New Hampshire) |
| ABSTRACT | A data clustering device includes an input configured to receive a plurality of data points encoded in at least one signal and a hardware logic circuit configured to extract one or more features of the one or more data points from the at least one signal, create or update, based on the one or more features, one or more data clusters representing one or more of the data points, and encode at least one of the one or more data clusters in at least one output signal. The device further includes an output configured to provide the at least one output signal, for instance, to a processor, such as a processor for controlling a controlled system. The device can be further configured to split or merge the data cluster(s) based on a statistical distribution of the one or more data points in the respective data cluster. |
| FILED | Thursday, March 18, 2021 |
| APPL NO | 17/205161 |
| ART UNIT | 2167 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/285 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11463639 | Botts et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| ASSIGNEE(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| INVENTOR(S) | Steven Botts (Santa Barbara, California); Bryan W. Kean (Denver, Colorado); Richard J. Peralta (Santa Barbara, California); John L. Vampola (Goleta, California); Micky R. Harris (Lompoc, California) |
| ABSTRACT | A TDI scanner including a dynamically programmable focal plane array including a two-dimensional array of detectors arranged in a plurality of columns and a plurality of rows, the array being divided into a plurality of banks separated from one another by gap regions, each bank including a plurality of sub-banks, and each sub-bank including at least one row of detectors, a ROIC coupled to the focal plane array and configured to combine in a TDI process outputs from detectors in each column of detectors in each sub-bank, and a controller configured to program the focal plane array to selectively and dynamically set characteristics of the focal plane array, the characteristics including a size and a location within the two-dimensional array of each of the plurality of sub-banks and the gap regions, the size corresponding to a number of rows of detectors included in the respective sub-bank or gap region. |
| FILED | Friday, November 06, 2020 |
| APPL NO | 17/091689 |
| ART UNIT | 2488 — Recording and Compression |
| CURRENT CPC | Pictorial Communication, e.g Television H04N 5/332 (20130101) H04N 5/378 (20130101) H04N 5/3592 (20130101) H04N 5/36961 (20180801) Original (OR) Class H04N 5/37213 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, October 04, 2022.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
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You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20221004.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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