FedInvent™ Patents

Patent Details for Tuesday, October 18, 2022 

This page was updated on Wednesday, October 19, 2022 at 03:36 PM GMT

Department of Health and Human Services (HHS) 

US 11471045 Tang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Oregon Health and Science University (Portland, Oregon)
ASSIGNEE(S) OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon)
INVENTOR(S) Maolong Tang (Portland, Oregon);  Yan Li (Portland, Oregon);  David Huang (Portland, Oregon)
ABSTRACT Disclosed are systems and methods for characterizing corneal shape abnormalities. These methods may be used to differentiate corneas having subclinical keratoconus from other conditions which cause distortion of corneal shape, including warpage of the cornea due to contact lens wear. Also disclosed is classification scheme to aid diagnosis of corneal conditions and thereby guide clinical decision making regarding patient treatment. This classification scheme is based on computed properties of corneal shape, is amenable to automation, and may be implemented in an integrated system or provided in the form of software encoded on a computer-readable medium.
FILED Wednesday, August 21, 2019
APPL NO 16/547110
ART UNIT 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 3/0025 (20130101)
A61B 3/102 (20130101)
A61B 3/107 (20130101) Original (OR) Class
A61B 3/1005 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/6267 (20130101)

Image Data Processing or Generation, in General
G06T 7/0014 (20130101)
G06T 7/0016 (20130101)
G06T 7/60 (20130101)
G06T 7/62 (20170101)
G06T 2207/10101 (20130101)
G06T 2207/30041 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471047 Klin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) CHILDREN'S HEALTHCARE OF ATLANTA, INC. (Atlanta, Georgia)
ASSIGNEE(S) Children's Healthcare of Atlanta, Inc. (Atlanta, Georgia)
INVENTOR(S) Ami Klin (Atlanta, Georgia);  Warren Jones (Decatur, Georgia)
ABSTRACT Systems, devices, and methods are described for assessing the risk of developmental, cognitive, social, or mental abilities or disabilities in very young patients (e.g., in the first 2-6 months of life). Generally, the decline in visual fixation of a subject over time with respect to certain dynamic stimuli provides a marker of possible abilities or disabilities (such as ASD). The visual fixation of the subject is identified, monitored, and tracked over time through repeated eye tracking sessions, and data relating to the visual fixation is then analyzed to determine a possible increased risk certain conditions in the subject. A change in visual fixation as compared to similar visual fixation data of typically-developing subjects or to a subject's own, prior visual fixation data provides an indication of a developmental, cognitive, or mental ability or disability.
FILED Friday, March 06, 2020
APPL NO 16/810995
ART UNIT 2872 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 3/0025 (20130101)
A61B 3/113 (20130101) Original (OR) Class
A61B 5/163 (20170801)
A61B 5/167 (20130101)
A61B 5/168 (20130101)
A61B 2503/04 (20130101)
A61B 2503/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471057 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) WASHINGTON UNIVERSITY (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Lihong Wang (St. Louis, Missouri);  Lei Li (St. Louis, Missouri);  Liren Zhu (St. Louis, Missouri);  Cheng Ma (St. Louis, Missouri)
ABSTRACT A single-impulse panoramic photoacoustic computed tomography (SIP-PACT) system for small-animal whole-body imaging is disclosed. In addition, a dual-speed of sound image universal back-projection reconstruction method is disclosed. Further, a PACT system for imaging a breast of a subject is disclosed.
FILED Wednesday, November 29, 2017
APPL NO 16/464958
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/024 (20130101)
A61B 5/0091 (20130101)
A61B 5/0095 (20130101) Original (OR) Class
A61B 5/113 (20130101)
A61B 5/318 (20210101)
A61B 5/721 (20130101)
A61B 2562/0247 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/1702 (20130101)
G01N 21/4795 (20130101)
G01N 29/06 (20130101)
G01N 29/0672 (20130101)
G01N 29/2418 (20130101)
G01N 2291/02475 (20130101)

Image Data Processing or Generation, in General
G06T 11/006 (20130101)
G06T 2211/421 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471063 Denney, Jr. et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Auburn University (Auburn, Alabama);  Arcus-Med, LLC (Raleigh, North Carolina);  The UAB Research Foundation (Birmingham, Alabama)
ASSIGNEE(S) Auburn University (Auburn, Alabama);  Areus-Med, LLC (Raleigh, North Carolina);  The UAB Research Foundation (Birmingham, Alabama)
INVENTOR(S) Thomas S. Denney, Jr. (Auburn, Alabama);  Himanshu Gupta (Ridgewood, New Jersey);  Ankur Gupta (Detroit, Michigan)
ABSTRACT A computerized information processing method for evaluating blood vessels is provided. The method includes acquiring a series of sequences of measurements, each at different time points in at least one cardiac cycle and at a different point along a blood vessel segment of a subject, generating corresponding profiles, calculating a transfer function for a subsegment between two selected points along a blood flow direction, and based thereon determining the physiological property of the subsegment. The measurements can contain information of blood velocity or blood pressure. A processing device and system implementing the information processing method are also provided. This approach can be used to evaluate arteries or veins and can be applied in screening, diagnosis, or prognosis of a variety of vascular diseases. For example, when combined with MRI scan, this approach can be used for non-invasively diagnosing pulmonary hypertension (PH) and chronic obstructive pulmonary disease (COPD), etc.
FILED Friday, June 12, 2020
APPL NO 16/900734
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/021 (20130101)
A61B 5/055 (20130101)
A61B 5/0245 (20130101)
A61B 5/0263 (20130101) Original (OR) Class
A61B 5/0285 (20130101)
A61B 5/681 (20130101)
A61B 5/02007 (20130101)
A61B 5/6852 (20130101)
A61B 5/7246 (20130101)
A61B 8/04 (20130101)
A61B 8/06 (20130101)
A61B 8/488 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/5601 (20130101)
G01R 33/5635 (20130101)
G01R 33/5673 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471101 del Alamo de Pedro et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Regents of the University of California (5th Floor, California);  Fundación para la Investigación Biomédica del Hospital Gregorio Marañó (Madrid, Spain)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  Fundación para la Investigación Biomédica del Hospital Gregorio Marañó (Madrid, Spain)
INVENTOR(S) Juan Carlos del Alamo de Pedro (San Diego, California);  Lorenzo Rossini (San Diego, California);  Andrew Kahn (San Diego, California);  Javier Bermejo (Madrid, Spain);  Pablo Martinez-Legazpi (Madrid, Spain);  Raquel Yotti Alvarez (Madrid, Spain)
ABSTRACT Provided herein are methods for in-vivo assessment of intraventricular flow shear stress, risk of hemolysis, also the location and extent of blood flow stasis regions and inside a cardiac chamber or blood vessel. Also provided herein are systems for performing such methods. Also provided herein are methods for assessing hemolysis and/or thrombosis risk in patients implanted with an LVAD. LVAD positioning and/or speed may be adjusted based on the results obtained by using methods described herein, and the risk for hemolysis and/or thrombosis can be minimized.
FILED Friday, April 05, 2019
APPL NO 17/045351
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101)
A61B 5/0263 (20130101)
A61B 5/0285 (20130101)
A61B 5/02035 (20130101)
A61B 5/4851 (20130101) Original (OR) Class
A61B 5/7225 (20130101)
A61B 8/065 (20130101)
A61B 8/485 (20130101)
A61B 8/488 (20130101)
A61B 8/0883 (20130101)
A61B 8/5223 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 60/178 (20210101)
A61M 60/857 (20210101)
A61M 2205/04 (20130101)
A61M 2250/00 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 30/40 (20180101)
G16H 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471135 Park et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Small Business Technology Transfer (STTR)
APPLICANT(S) Intelligent Fiber Optic Systems, Inc. (Santa Clara, California)
ASSIGNEE(S) Intelligent Fiber Optic Systems, Inc. (San Jose, California)
INVENTOR(S) Yong-Lae Park (Stanford, California);  Richard James Black (Menlo Park, California);  Behzad Moslehi (Los Altos, California);  Mark R. Cutkosky (Stanford, California);  Santhi Elayaperumal (Stanford, California);  Bruce Daniel (Stanford, California);  Alan Yeung (Stanford, California);  Vahid Sotoudeh (Los Altos, California)
ABSTRACT A biopsy needle has a central axis and includes one or more sensing regions, each sensing region formed by a plurality of sensing optical fibers located over a particular extent of said central axis and inside the outer shell of the needle. The sensing optical fibers are coupled to a wavelength interrogator. A steerable catheter has a central axis and outer shell, the outer shell coupled to a plurality of optical fibers in sensing regions and actuation regions, the sensing regions formed over particular extents of the central axis by bonding gratings to the inner surface of the outer shell, and the actuation regions formed by coupling optical energy into shape memory alloys bonded to the outer shell.
FILED Monday, February 11, 2019
APPL NO 16/271883
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 10/0233 (20130101) Original (OR) Class
A61B 18/1492 (20130101)
A61B 90/06 (20160201)
A61B 2017/00057 (20130101)
A61B 2017/00867 (20130101)
A61B 2034/2061 (20160201)
A61B 2090/064 (20160201)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 25/0043 (20130101)
A61M 25/0105 (20130101)
A61M 25/0133 (20130101)
A61M 25/0158 (20130101)
A61M 2025/0166 (20130101)
A61M 2205/0266 (20130101)
A61M 2205/3306 (20130101)

Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 1/246 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471260 MacEwan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S) Washington University (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Matthew R. MacEwan (St. Louis, Missouri);  Jingwei Xie (St. Louis, Missouri);  Zack Ray (St. Louis, Missouri);  Younan Xia (St. Louis, Missouri)
ABSTRACT A multi-laminar electrospun nanofiber scaffold for use in repairing a defect in a tissue substrate is provided. The scaffold includes a first layer formed by a first plurality of electrospun polymeric fibers, and a second layer formed by a second plurality of electrospun polymeric fibers. The second layer is combined with the first layer. A first portion of the scaffold includes a higher density of fibers than a second portion of the scaffold, and the first portion has a higher tensile strength than the second portion. The scaffold is configured to degrade via hydrolysis after at least one of a predetermined time or an environmental condition. The scaffold is configured to be applied to the tissue substrate containing the defect, and is sufficiently flexible to facilitate application of the scaffold to uneven surfaces of the tissue substrate, and to enable movement of the scaffold by the tissue substrate.
FILED Tuesday, October 27, 2020
APPL NO 17/081228
ART UNIT 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/02 (20130101) Original (OR) Class
A61F 2/0063 (20130101)
A61F 2/105 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 15/22 (20130101)
A61L 15/42 (20130101)
A61L 27/14 (20130101)
A61L 27/50 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 48/05 (20190201)
B29C 48/142 (20190201)

Apparatus for Enzymology or Microbiology;
C12M 25/14 (20130101)

Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons
D01D 5/0076 (20130101)
D01D 5/0092 (20130101)

Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding
D04H 1/728 (20130101)
D04H 3/016 (20130101)
D04H 3/073 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471306 Goldfarb et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) Michael Goldfarb (Franklin, Tennessee);  Almaskhan Baimyshev (Nashville, Tennessee);  Harrison Bartlett (Nashville, Tennessee);  Jantzen Lee (Nashville, Tennessee)
ABSTRACT The present disclosure provides for a device and method of control for an artificial prosthetic knee. A prosthetic knee according to the present disclosure relies on strictly passive means of providing support during weight bearing and supplements a resistive swing-phase mechanism with a small powered actuator. This actuator adds power to the knee, exclusively during swing phase, to improve swing-phase behavior. In particular, the knee still relies on the resistive swing-phase mechanism to provide nominal swing-phase knee motion, but supplements that motion as needed with the small powered actuator.
FILED Friday, January 25, 2019
APPL NO 16/961723
ART UNIT 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/70 (20130101)
A61F 2/74 (20210801)
A61F 2/644 (20130101) Original (OR) Class
A61F 2/741 (20210801)
A61F 2/748 (20210801)
A61F 2002/701 (20130101)
A61F 2002/704 (20130101)
A61F 2002/764 (20130101)
A61F 2002/5006 (20130101)
A61F 2002/5033 (20130101)
A61F 2002/5035 (20130101)
A61F 2002/7625 (20130101)
A61F 2002/7635 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471326 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California);  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Lihong Wang (Arcadia, California);  Frank L. Brodie (San Francisco, California);  Yuecheng Shen (Pasadena, California);  Yan Liu (Pasadena, California);  Haowen Ruan (Pasadena, California)
ABSTRACT A device for irradiating ocular tissue, including a source of electromagnetic radiation; a beacon scattering the electromagnetic radiation transmitted through an opacity in ocular tissue so as to form scattered electromagnetic radiation; a modulator transmitting output electromagnetic radiation having a field determined from a recording of the scattered electromagnetic radiation transmitted through the opacity, so that the output electromagnetic radiation is transmitted through the opacity to the beacon. The device can be used to treat amblyopia or correct optical aberrations in corneal or lens tissue.
FILED Thursday, November 01, 2018
APPL NO 16/178190
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 9/00814 (20130101) Original (OR) Class
A61F 9/00817 (20130101)
A61F 2009/0087 (20130101)
A61F 2009/00844 (20130101)
A61F 2009/00863 (20130101)
A61F 2009/00887 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471330 Kilgard et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S) The Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Michael P. Kilgard (Richardson, Texas);  Navzer Engineer (Plano, Texas);  David Michael Pierce (Plano, Texas)
ABSTRACT A method of treating tinnitus comprising measuring a patient's hearing, determining the patient's hearing loss and the patient's tinnitus frequency using the measurements of the patient's hearing, programming a clinical controller with the measurements of the patient's hearing, selecting a plurality of therapeutic tones, where the therapeutic tones are selected to be at least a half-octave above or below of the patient's tinnitus frequency, setting an appropriate volume for each of the plurality of tones, repetitively playing each of the plurality of therapeutic tones, and pairing a vagus nerve stimulation pulse train with each playing of a therapeutic tone, thereby reducing the patient's perception of tinnitus.
FILED Thursday, February 02, 2017
APPL NO 15/422958
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/128 (20130101)

Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 11/00 (20130101) Original (OR) Class

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/361 (20130101)
A61N 1/0551 (20130101)
A61N 1/36053 (20130101)
A61N 1/36092 (20130101)
A61N 1/36132 (20130101)
A61N 1/36167 (20130101)
A61N 1/36171 (20130101)
A61N 1/36178 (20130101)
A61N 1/37235 (20130101)
A61N 1/37247 (20130101)

Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 23/28 (20130101)

Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems
H04R 25/75 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471335 Jabbarzadeh et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
APPLICANT(S) UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina)
ASSIGNEE(S) University of South Carolina (Columbia, South Carolina)
INVENTOR(S) Ehsan Jabbarzadeh (Columbia, South Carolina);  Sara Eslambolchimoghadam (Columbia, South Carolina)
ABSTRACT Wound dressings, methods for forming the wound dressings, and methods for using the wound dressings are described. Wound dressings include a crosslinked hydrogel matrix and a plurality of porous absorbent microspheres encapsulated in the crosslinked matrix. The hydrogel matrix and the microspheres can include the same or different hydrogel polymers, e.g., alginates or the like. The wound dressings can be used in treating chronic wounds and burn wounds and can promote autolytic debridement.
FILED Tuesday, August 13, 2019
APPL NO 16/539192
ART UNIT 3786 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 13/00068 (20130101)
A61F 13/0213 (20130101) Original (OR) Class
A61F 13/0223 (20130101)
A61F 2013/530802 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 15/28 (20130101)
A61L 15/60 (20130101)
A61L 15/325 (20130101)
A61L 15/425 (20130101)
A61L 27/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471443 Tang et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida);  The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland);  THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S) FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida);  The United States of America, as represented by the Secretary, Department of Health and Human Service (Bethesda, Maryland);  THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
INVENTOR(S) Hengli Tang (Tallahassee, Florida);  Emily M. Lee (Tallahassee, Florida);  Wei Zheng (Rockville, Maryland);  Ruili Huang (Rockville, Maryland);  Miao Xu (Rockville, Maryland);  Wenwei Huang (Rockville, Maryland);  Khalida Shamim (Rockville, Maryland);  Guoli Ming (Philadelphia, Pennsylvania);  Hongjun Song (Philadelphia, Pennsylvania)
ABSTRACT The present invention concerns the use of compounds and compositions for the treatment or prevention of Flavivirus infections, such as dengue virus infections and Zika virus infections. Aspects of the invention include methods for treating or preventing Flavivirus virus infection, such as dengue virus and Zika virus infection, by administering a compound or composition of the invention, to a subject in need thereof; methods for inhibiting Flavivirus infections, such as dengue virus and Zika virus infections, in a cell in vitro or in vivo; pharmaceutical compositions; packaged dosage formulations; and kits useful for treating or preventing Flavivirus infections, such as dengue virus and Zika virus infections.
FILED Wednesday, April 29, 2020
APPL NO 16/861281
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/165 (20130101)
A61K 31/245 (20130101)
A61K 31/336 (20130101)
A61K 31/352 (20130101)
A61K 31/422 (20130101)
A61K 31/427 (20130101)
A61K 31/433 (20130101)
A61K 31/506 (20130101)
A61K 31/517 (20130101)
A61K 31/519 (20130101)
A61K 31/554 (20130101)
A61K 31/4162 (20130101)
A61K 31/4184 (20130101) Original (OR) Class
A61K 31/4535 (20130101)
A61K 31/4709 (20130101)
A61K 31/4741 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471460 DePamphilis et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of Americans represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Melvin L. DePamphilis (Olney, Maryland);  Gaurav Sharma (New Delhi, India);  Juan Jose Marugan (Gaithersburg, Maryland);  Marc Ferrer (Potomac, Maryland);  Ajit Roy (Rockville, Maryland)
ABSTRACT Disclosed is method for treating cancer in a mammal, comprising administering to a mammal in need thereof a compound of the formula:
wherein R1, R2, and R3 are as defined herein, wherein the cancer is an autophagy-dependent cancer, in an amount sufficient to induce autophagy in the cell and cause the death of cancer cells. Also disclosed is a method for selectively killing cancer cells in a patient afflicted with cancer, comprising administering to the mammal, wherein the cancer cells are autophagy-dependent cancer cells, in an amount sufficient to induce autophagy in the cells and cause the death of the cancer cells.
FILED Tuesday, May 26, 2020
APPL NO 16/883046
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/53 (20130101) Original (OR) Class
A61K 31/506 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Heterocyclic Compounds
C07D 239/50 (20130101)
C07D 251/54 (20130101)
C07D 403/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471461 Boden et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) Emory University (Atlanta, Georgia);  The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) Emory University (Atlanta, Georgia);  US Govt represented by Dept of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Scott D. Boden (Atlanta, Georgia);  Sreedhara Sangadala (Atlanta, Georgia)
ABSTRACT The disclosure relates to compounds and compositions for forming bone and methods related thereto. In one embodiment, the disclosure relates to a composition comprising a compound disclosed herein, such as 2,4-diamino-1,3,5-triazine derivatives or salts thereof, for use in bone growth processes. In a typical embodiment, a bone graft composition is implanted in a subject at a site of desired bone growth or enhancement.
FILED Tuesday, December 15, 2020
APPL NO 17/122853
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/53 (20130101) Original (OR) Class
A61K 31/53 (20130101)
A61K 38/1875 (20130101)
A61K 2300/00 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/54 (20130101)
A61L 2300/412 (20130101)
A61L 2430/02 (20130101)

Heterocyclic Compounds
C07D 251/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471477 Clarke et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Chan Zuckerberg Biohub, Inc. (San Francisco, California);  The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) Chan Zuckerberg Biohub, Inc. (San Francisco, California);  The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Michael F. Clarke (San Francisco, California);  Robert W. Hsieh (San Francisco, California)
ABSTRACT The invention is directed to methods of treating TNBC in a patient by administering to the patient an agent that inhibits the expression or activity of cyclin-dependent kinase 19 (CDK19). In some embodiments, the agent may be a small molecule inhibitor, a polynucleotide (e.g., shRNA. siRNA), or a protein (e.g., an antibody). In some embodiments, the agent does not inhibit the activity or expression of CDK8.
FILED Tuesday, September 18, 2018
APPL NO 16/648088
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/713 (20130101) Original (OR) Class
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)
C12N 2310/14 (20130101)
C12N 2310/531 (20130101)
C12N 2320/30 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57415 (20130101)
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471487 Zhao et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Yangbing Zhao (Lumberton, New Jersey);  Xiaojun Liu (Swarthmore, Pennsylvania);  Carl H. June (Merion Station, Pennsylvania)
ABSTRACT The present invention includes a method for expanding a population of electroporated T cells. The method includes electroporating a population of cells comprising T cells with mRNA encoding a chimeric membrane protein comprising an antigen binding domain to a molecule and an intracellular domain of a co-stimulatory molecule, wherein the cultured T cells expand at least 10 fold. The invention further includes an expanded population of T cells, compositions comprising the cells and methods of treatment.
FILED Friday, October 30, 2015
APPL NO 15/521741
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 1/02 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101) Original (OR) Class
A61K 48/00 (20130101)
A61K 2035/124 (20130101)
A61K 2039/505 (20130101)

Peptides
C07K 14/705 (20130101)
C07K 14/7051 (20130101)
C07K 14/7151 (20130101)
C07K 14/70517 (20130101)
C07K 14/70521 (20130101)
C07K 14/70596 (20130101)
C07K 16/30 (20130101)
C07K 16/2809 (20130101)
C07K 2317/622 (20130101)
C07K 2319/02 (20130101)
C07K 2319/03 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0636 (20130101)
C12N 2501/51 (20130101)
C12N 2510/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471495 Pamer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York)
ASSIGNEE(S) MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York)
INVENTOR(S) Eric Pamer (Guilford, Connecticut);  Charlie Buffie (New York, New York);  Peter McKenney (New York, New York)
ABSTRACT The present invention relates to methods and compositions for reducing the risk and severity of C. difficile infection. It is based, at least in part, on the discovery that a restricted fraction of the gut microbiota, including the bacterium Clostridium scindens, contributes substantially to resistance against C. difficile infection. Without being bound by any particular theory, it is believed that this is achieved through the biosynthesis of secondary bile acids.
FILED Friday, July 26, 2019
APPL NO 16/523414
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/74 (20130101) Original (OR) Class
A61K 38/443 (20130101)
A61K 45/06 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/0006 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/26 (20130101)

Enzymes
C12Y 101/01159 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471496 Keck et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) ROWAN UNIVERSITY (Glassboro, New Jersey);  THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado)
ASSIGNEE(S) Rowan University (Glassboro, New Jersey);  The Regents of the University of Colorado (Denver, Colorado)
INVENTOR(S) Thomas M. Keck (Philadelphia, Pennsylvania);  Christopher A. Lowry (Boulder, Colorado)
ABSTRACT The present invention provides compositions and methods for treating, ameliorating, and/or preventing cocaine addiction in a subject. Immunization by M. vaccae alters serotonin signaling in the brain, reducing stress- and anxiety-like responding in animal models of post-traumatic stress disorder and other anxiety disorders. In certain embodiments, the immunoregulatory, anti-stress, and anxiolytic effects of M. vaccae immunization reduces addiction- and relapse-like responding in models of cocaine addiction and alter the development of cocaine-induced neuroinflammation.
FILED Friday, February 28, 2020
APPL NO 16/804815
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/74 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471506 Waller et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Emory University (Atlanta, Georgia);  Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Emory University (Atlanta, Georgia);  Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Edmund K. Waller (Atlanta, Georgia);  Rebecca Pankove (Atlanta, Georgia);  Susan Thomas (Atlanta, Georgia);  Sruthi Ravindranathan (Atlanta, Georgia)
ABSTRACT This disclosure relates to methods of treating cancer or viral infections comprising administering an effective amount of a VIP antagonist in combination with an immune check-point inhibitor to a subject in need thereof. In certain embodiments, the immune check-point inhibitor is an anti-PD1 or anti-PDL1 antibody.
FILED Wednesday, April 24, 2019
APPL NO 17/050376
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/16 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 16/2818 (20130101)
C07K 16/2827 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471509 Olson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Board of Regents of the University of Texas System (Austin, Texas)
ASSIGNEE(S) The Board of Regents of The University of Texas System (Austin, Texas)
INVENTOR(S) Eric Olson (Dallas, Texas);  Douglas P. Millay (Frisco, Texas)
ABSTRACT The present disclosure describes the fusogenic activity of the Myomaker protein. This polypeptide, when expressed in non-muscle cells, is able to drive fusion of the cell with a muscle cell, but not with other non-muscle cells. The use of this protein and cell expressing it in the delivery of exogenous genetic material to muscle cells also is described.
FILED Tuesday, April 09, 2019
APPL NO 16/379610
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 38/1719 (20130101) Original (OR) Class
A61K 45/06 (20130101)

Peptides
C07K 14/4716 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/16 (20130101)
C12N 15/02 (20130101)
C12N 2740/10043 (20130101)
C12N 2740/10071 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471515 Shi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts);  Children's Medical Center Corporation (Boston, Massachusetts)
ASSIGNEE(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts);  Children's Medical Center Corporation (Boston, Massachusetts)
INVENTOR(S) Jinjun Shi (Boston, Massachusetts);  Mohammad Ariful Islam (Quincy, Massachusetts);  Yingjie Xu (Newton, Massachusetts);  Omid C. Farokhzad (Waban, Massachusetts);  Bruce Zetter (Wayland, Massachusetts)
ABSTRACT Compositions and methods for treating cancer that include administering a therapeutically effective amount of a tumor suppressor mRNA complexed with a delivery vehicle as described herein, e.g., a nanoparticle.
FILED Thursday, November 09, 2017
APPL NO 16/348383
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5146 (20130101)
A61K 9/5153 (20130101)
A61K 38/465 (20130101) Original (OR) Class
A61K 47/595 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471517 Serody et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina);  Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina);  Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Jonathan Serody (Chapel Hill, North Carolina);  James Coghill (Chapel Hill, North Carolina);  Danny Bruce (Chapel Hill, North Carolina);  Bruce Blazar (Golden Valley, Minnesota);  Heather Stefanski (Minneapolis, Minnesota);  Benjamin Vincent (Chapel Hill, North Carolina)
ABSTRACT ILC2 cells play a role in the pathogenesis of graft versus host disease (GvHD) and idiopathic pneumonia syndrome (IPS), both conditions associated with allogeneic stem cell transplantation. Infusion of IL-33 activated ILC2 cells into patients with ongoing GvHD or IPS, or prior to onset of GvHD or IPS in susceptible patients, substantially ameliorates the disease and improves survival.
FILED Thursday, October 10, 2019
APPL NO 16/598914
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101)
A61K 35/28 (20130101)
A61K 35/28 (20130101)
A61K 39/001 (20130101) Original (OR) Class
A61K 2035/122 (20130101)
A61K 2035/124 (20130101)
A61K 2039/577 (20130101)
A61K 2039/5154 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 11/00 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0634 (20130101)
C12N 5/0651 (20130101)
C12N 2501/2307 (20130101)
C12N 2501/2333 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471520 Barry et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) University Of Maryland, Baltimore (Baltimore, Maryland)
ASSIGNEE(S) University Of Maryland, Baltimore (Baltimore, Maryland)
INVENTOR(S) Eileen M. Barry (Ellicott City, Maryland);  Myron M. Levine (Columbia, Maryland)
ABSTRACT The invention relates to a multivalent Shigella/Enterotoxigenic Escherichia coli vaccine for use in prophylaxis and treatment of diarrheal disease. The Shigella-ETEC vaccine provides increased coverage of a broader range of ETEC and Shigella isolates than prior vaccines, and includes CS14 antigens and serotypes (S. flexneri 7a, or S. flexneri 1b).
FILED Wednesday, April 03, 2019
APPL NO 17/042671
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/0258 (20130101)
A61K 39/0283 (20130101) Original (OR) Class
A61K 2039/70 (20130101)
A61K 2039/522 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471526 Zhu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) University of Maryland, College Park (College Park, Maryland)
ASSIGNEE(S) University of Maryland, College Park (College Park, Maryland)
INVENTOR(S) Xiaoping Zhu (Clarksville, Maryland);  Xiaoyang Liu (Adelphi, Maryland)
ABSTRACT HCMV US11 based therapeutics that can be used to target and reduce the activity of the FcRn protein are provided. Methods of treating auto-immune mediated and albumin-mediated diseases in a subject are provided that comprise administration of HCMV US11 protein, polypeptide fragments, or variants thereof, as well as methods for preventing, or treating, infections of HCMV through administration of a US11 inhibitor. US11 protein containing vaccine compositions are also provided for stimulation of an anti-US11 immune response for protection against HCMV infection.
FILED Monday, February 24, 2020
APPL NO 16/799605
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/162 (20130101)
A61K 39/245 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/1131 (20130101)
C12N 2710/16133 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471535 Pei
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Ohio State Innovation Foundation (Columbus, Ohio)
ASSIGNEE(S) Ohio State Innovation Foundation (Columbus, Ohio)
INVENTOR(S) Dehua Pei (Columbus, Ohio)
ABSTRACT The present disclosure provides novel polypeptide conjugates. The polypeptide conjugates disclosed herein comprise a stapled peptide comprising a peptide and at least one staple which holds the peptide in an α-helical conformation, and a cyclic cell-penetrating peptide (cCPP) conjugated, directly or indirectly, to the stapled peptide. The present disclosure demonstrates that cCPPs can be used to confer consistent cell-permeability to stapled peptides.
FILED Sunday, October 28, 2018
APPL NO 16/759600
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/58 (20170801)
A61K 47/64 (20170801) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/001 (20130101)
C07K 14/4703 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471557 Stewart
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah)
ASSIGNEE(S) UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah)
INVENTOR(S) Russell J. Stewart (Salt Lake City, Utah)
ABSTRACT Described herein are fluid complex coacervates that produce solid adhesives in situ. Oppositely charged polyelectrolytes were designed to form fluid adhesive complex coacervates at ionic strengths higher than the ionic strength of the application site, but an insoluble adhesive solid or gel at the application site. When the fluid, high ionic strength adhesive complex coacervates are introduced into the lower ionic strength application site, the fluid complex coacervate is converted to a an adhesive solid or gel as the salt concentration in the complex coacervate equilibrates to the application site salt concentration. In one embodiment, the fluid complex coacervates are designed to solidify in situ at physiological ionic strength and have numerous medical applications. In other aspects, the fluid complex coacervates can be used in aqueous environment for non-medical applications.
FILED Friday, June 26, 2020
APPL NO 16/912830
ART UNIT 1699 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/0043 (20130101)
A61K 49/0054 (20130101)
A61K 49/0073 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 24/02 (20130101)
A61L 24/10 (20130101)
A61L 24/0015 (20130101)
A61L 24/0031 (20130101)
A61L 24/0042 (20130101)
A61L 24/043 (20130101)
A61L 24/043 (20130101)
A61L 24/046 (20130101) Original (OR) Class
A61L 24/104 (20130101)
A61L 2300/44 (20130101)
A61L 2300/416 (20130101)
A61L 2430/02 (20130101)
A61L 2430/36 (20130101)

Compositions of Macromolecular Compounds
C08L 89/00 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 5/1668 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471565 Alsberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio);  WORCESTER POLYTECHNIC INSTITUTE (Worcester, Massachusetts)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio);  WORCESTER POLYTECHNIC INSTITUTE (Worcester, Massachusetts)
INVENTOR(S) Eben Alsberg (Cleveland, Ohio);  Anna D. Dikina (Cleveland, Ohio);  Marsha W. Rolle (Worcester, Massachusetts)
ABSTRACT A modular engineered tissue construct includes a plurality of fused self-assembled, scaffold-free, high-density cell aggregates. At least one cell aggregate includes a plurality of cells and a plurality of biocompatible and biodegradable nanoparticles and/or microparticles that are incorporated within the cell aggregates. The nanoparticles and/or microparticles acting as a bulking agent within the cell aggregate to increase the cell aggregate size and/or thickness and improve the mechanical properties of the cell aggregate as well as to deliver bioactive agents.
FILED Monday, March 09, 2015
APPL NO 15/258666
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/54 (20130101)
A61L 27/3804 (20130101)
A61L 27/3882 (20130101) Original (OR) Class
A61L 2300/62 (20130101)
A61L 2300/414 (20130101)
A61L 2300/602 (20130101)
A61L 2400/12 (20130101)
A61L 2430/22 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0075 (20130101)
C12N 2513/00 (20130101)
C12N 2531/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471674 Weber et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Stephen Weber (Allison Park, Pennsylvania);  Amir H. Faraji (Pittsburgh, Pennsylvania);  Yifat Guy (Newtown Square, Pennsylvania);  Andrea Jaquins-Gerstl (Oakdale, Pennsylvania);  Alec C. Valenta (South Park, Pennsylvania)
ABSTRACT Apparatuses and methods for electrokinetic transport of fluids to patients. Drug-containing solutions may be placed in vial-like reservoir, which is connected to an apparatus such as a traditional catheter or other device capable of holding a drug-containing solution. Instead of a vial-like reservoir, a doped infusion pad or a gel may be used as a source of the drug-containing solution. The reservoir and apparatus may thus be the same component. The methods and apparatuses disclosed herein may also be used to transport fluid alone to achieve a clinical effect. The apparatus is placed at the point of drug delivery. The counter-electrode may be placed in or on a patient. Current is passed from the reservoir to the counter-electrode. Through electrokinetic transport, drug-containing solution is delivered along a current path from the drug source to the counter-electrode. A hollow fiber catheter for use in electrokinetic transport is also disclosed.
FILED Tuesday, December 12, 2017
APPL NO 15/839712
ART UNIT 3783 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 37/00 (20130101)
A61M 2037/0007 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/306 (20130101)
A61N 1/325 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11472764 Shulman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Yale University (New Haven, Connecticut)
ASSIGNEE(S) Yale University (New Haven, Connecticut)
INVENTOR(S) Gerald I. Shulman (East Haven, Connecticut);  David A. Spiegel (New Haven, Connecticut)
ABSTRACT The present invention includes DNP derivatives that are useful for preventing or treating a metabolic disease or disorder in a subject in need thereof. In certain embodiments, the subject is further administered at least one additional therapeutic agent.
FILED Tuesday, July 28, 2020
APPL NO 16/940491
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/085 (20130101)

Acyclic or Carbocyclic Compounds
C07C 205/37 (20130101) Original (OR) Class

Steroids
C07J 41/0055 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11472776 Davidowitz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) OLIGOMERIX INC. (Bronx, New York)
ASSIGNEE(S) Oligomerix, Inc. (White Plains, New York)
INVENTOR(S) Eliot J. Davidowitz (West Hempstead, New York);  James G. Moe (Stamford, Connecticut);  Allen B. Reitz (Lansdale, Pennsylvania);  Haiyan Bian (Princeton, New Jersey);  Charles Gluchowski (Danville, California);  James Hendrix (Wilmington, Massachusetts);  Albert S. Yehaskel (Great Neck, New York);  Mark E. McDonnell (Lansdale, Pennsylvania);  H. Marie Loughran (Perkasie, Pennsylvania)
ABSTRACT Novel quinazolinones useful as inhibitors of tau oligomer formation, useful for the treatment of neurodegenerative diseases and related conditions are disclosed. The invention also relates to the pharmaceutically acceptable salts of said compounds, processes for the preparation of said compounds, intermediates used in the preparation of said compounds, and pharmaceutical compositions containing said compounds. The invention further relates to methods of use of said compounds, salts of said compounds, and said compositions in treating neurodegenerative diseases and related conditions.
FILED Monday, December 18, 2017
APPL NO 16/471363
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 45/06 (20130101)

Heterocyclic Compounds
C07D 239/91 (20130101) Original (OR) Class
C07D 401/04 (20130101)
C07D 401/14 (20130101)
C07D 471/04 (20130101)
C07D 495/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11472778 Schiffer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Celia Schiffer (Shrewsbury, Massachusetts);  Akbar Ali (Westborough, Massachusetts);  Ashley Matthew (Worcester, Massachusetts)
ABSTRACT The invention provides novel classes of HCV therapeutics that are orally available, safe and effective HCV NS3/4A protease inhibitors and are less susceptible to drug resistance than existing therapeutics. The invention also relates to pharmaceutical composition of these compounds and methods of preparation and use thereof.
FILED Tuesday, June 19, 2018
APPL NO 16/614843
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/498 (20130101)
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)

Heterocyclic Compounds
C07D 241/20 (20130101) Original (OR) Class

Peptides
C07K 5/101 (20130101)
C07K 5/0808 (20130101)
C07K 5/1016 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11472780 Villagra et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The George Washington University, a Congressionally Chartered Not-For-Profit Corporation (Washington, District of Columbia);  The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S) The George Washington University (Washington, District of Columbia);  The Board of Trustees ofthe University of Illinois (Urbana, Illinois)
INVENTOR(S) Alejandro Villagra (Falls Church, Virginia);  Alan P. Kozikowski (Chicago, Illinois);  Sida Shen (Chicago, Illinois)
ABSTRACT The present disclosure provides compounds represented by Formula (I): and pharmaceutically acceptable salts, solvates, e.g., hydrates, and prodrugs thereof wherein X and n are as defined as set forth in the specification. The present disclosure also provides compounds of Formula (I) for use to treat diseases and conditions, e.g., cancer, wherein inhibition of HDAC provides a benefit.
FILED Thursday, March 29, 2018
APPL NO 16/498651
ART UNIT 1699 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Heterocyclic Compounds
C07D 261/18 (20130101) Original (OR) Class
C07D 413/06 (20130101)
C07D 417/06 (20130101)
C07D 471/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11472812 Theodorescu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Regents of the University of Colorado, a body corporate (Denver, Colorado)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado)
INVENTOR(S) Dan Theodorescu (Englewood, Colorado);  Michael Fitzpatrick Wempe (Aurora, Colorado);  David Ross (Niwot, Colorado);  Chao Yan (Denver, Colorado);  Phillip Reigan (Denver, Colorado)
ABSTRACT Methods of inhibiting the growth or metastasis of a cancer in a subject by inhibiting a Ral GTPase in the subject, and small molecule inhibitors of Ral GTPases useful in the methods of the invention. Pharmaceutical compositions containing the compounds of the invention, and methods of using the same.
FILED Thursday, April 30, 2020
APPL NO 16/863867
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/4162 (20130101)
A61K 31/4162 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/04 (20180101)

Heterocyclic Compounds
C07D 491/052 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11472813 Brabander et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Dallas, Texas)
INVENTOR(S) Jef De Brabander (Dallas, Texas);  Daniel Rosenbaum (Dallas, Texas);  Qiren Liang (Dallas, Texas);  Wentian Wang (Dallas, Texas)
ABSTRACT Methods and compositions for agonizing a type-2 orexin receptor (OX2R) in a cell determined to be in need thereof, including the general method of (a) administering to a subject a cyclic guanidinyl OX2R agonist and (b) detecting a resultant enhanced wakefulness or increased resistance to diet-induced accumulation of body fat, or abbreviated recovery from general anesthesia or jet lag.
FILED Sunday, September 27, 2020
APPL NO 17/033879
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/422 (20130101)
A61K 31/423 (20130101)
A61K 31/427 (20130101)
A61K 31/428 (20130101)
A61K 31/501 (20130101)
A61K 31/506 (20130101)
A61K 31/4184 (20130101)
A61K 31/4192 (20130101)
A61K 31/4355 (20130101)
A61K 31/4439 (20130101)
A61K 31/4709 (20130101)

Heterocyclic Compounds
C07D 235/30 (20130101)
C07D 401/06 (20130101)
C07D 401/12 (20130101)
C07D 403/12 (20130101)
C07D 405/12 (20130101)
C07D 409/06 (20130101)
C07D 413/06 (20130101)
C07D 413/12 (20130101)
C07D 417/12 (20130101)
C07D 471/04 (20130101)
C07D 491/107 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11472843 Brady
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Rockefeller University (New York, New York)
ASSIGNEE(S) The Rockefeller University (New York, New York)
INVENTOR(S) Sean Brady (New York, New York)
ABSTRACT The present invention provides methods, compositions and articles of manufacture useful for the prophylactic and therapeutic amelioration and treatment of gram-positive bacteria, and related conditions. The invention provides compositions and methods incorporating and utilizing malacidin antibiotics, and derivatives and variants thereof.
FILED Friday, May 25, 2018
APPL NO 16/617052
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/07 (20130101)
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)

Peptides
C07K 7/56 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11472846 Bond et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) MOREHOUSE SCHOOL OF MEDICINE (Atlanta, Georgia)
ASSIGNEE(S) MOREHOUSE SCHOOL OF MEDICINE (Atlanta, Georgia)
INVENTOR(S) Vincent C. Bond (Stone Mountain, Georgia);  James W. Lillard, Jr. (Smyrna, Georgia);  Ming Bo Huang (Atlanta, Georgia)
ABSTRACT A method for treating a cancer comprises administering to a subject in need of such treatment an effective amount of a pharmaceutical composition comprising an anti-cancer agent having at least one secretion modifying region (SMR) peptide from HIV-1 Nef fused to at least one cell-penetrating peptide (CPP) or at least one Clusterin (Clu)-binding peptide (Clu-BP).
FILED Monday, October 12, 2020
APPL NO 17/068061
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/08 (20130101)
A61K 38/10 (20130101)
A61K 38/162 (20130101)
A61K 45/06 (20130101)
A61K 47/60 (20170801)
A61K 47/64 (20170801)
A61K 47/641 (20170801)
A61K 47/645 (20170801)

Peptides
C07K 14/00 (20130101)
C07K 14/005 (20130101) Original (OR) Class
C07K 2319/01 (20130101)
C07K 2319/035 (20130101)
C07K 2319/70 (20130101)
C07K 2319/74 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2740/16022 (20130101)
C12N 2740/16322 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11472849 Joung et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) J. Keith Joung (Winchester, Massachusetts);  Jeffry D. Sander (Ankeny, Iowa)
ABSTRACT The disclosure describes methods that include providing a first nucleic acid having a sequence encoding a first set comprising one or more transcription activator-like effector (TALE) repeat domains and/or one or more portions of one or more TALE repeat domains; contacting the first nucleic acid with a first enzyme, wherein the first enzyme creates a first ligatable end; providing a second nucleic acid having a sequence encoding a second set comprising one or more TALE repeat domains and/or one or more portions of one or more TALE repeat domains; contacting the second nucleic acid with a second enzyme, wherein the second enzyme creates a second ligatable end, and wherein the first and second ligatable ends are compatible; and ligating the first and second nucleic acids through the first and second ligatable ends to produce a first ligated nucleic acid, wherein the first ligated nucleic acid is linked to a solid support, and wherein the first ligated nucleic acid encodes a polypeptide comprising said first and second sets.
FILED Friday, February 22, 2019
APPL NO 16/283380
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 14/195 (20130101) Original (OR) Class
C07K 2319/00 (20130101)
C07K 2319/24 (20130101)
C07K 2319/41 (20130101)
C07K 2319/43 (20130101)
C07K 2319/80 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/66 (20130101)
C12N 15/1093 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/34 (20130101)
C12P 21/02 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101)
C12Q 1/6806 (20130101)
C12Q 2521/501 (20130101)
C12Q 2563/149 (20130101)

Enzymes
C12Y 301/00 (20130101)

Combinatorial Chemistry; Libraries, e.g Chemical Libraries
C40B 40/08 (20130101)
C40B 50/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11472857 Murphy Topp et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Elizabeth M. Murphy Topp (Lafayette, Indiana);  Hamed Tabatabaei Ghomi (San Diego, California);  Markus Lill (West Lafayette, Indiana);  Shenbaga Moorthy Balakrishnan (Virudhunagar District, India)
ABSTRACT The invention generally relates to modified glucagon molecules. In certain embodiments, the invention provides a glucagon molecule that includes one or more modified amino acids to result in the glucagon molecule being soluble at a substantially neutral pH and resistant to fibrillation. Modifications may include, for example, phosphorylation or sulfation.
FILED Wednesday, February 17, 2021
APPL NO 17/177799
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/26 (20130101)
A61K 47/52 (20170801)

Peptides
C07K 14/605 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11472859 Marsala
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Martin Marsala (La Jolla, California)
ABSTRACT The present invention provides a therapy for treating loss of GABA-mediated pre-synaptic inhibition after spinal injury. The therapeutic regimen includes spinal segment-specific upregulation of GAD65 (glutamate decarboxylase) and VGAT (vesicular GABA transporter) to modulate chronic spasticity in patients after spinal traumatic or ischemic injury.
FILED Monday, March 27, 2017
APPL NO 16/084912
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 48/005 (20130101)
A61K 48/0075 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/14 (20180101)

Acyclic or Carbocyclic Compounds
C07C 233/69 (20130101)
C07C 235/34 (20130101)
C07C 235/42 (20130101)

Peptides
C07K 14/70571 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/88 (20130101)
C12N 2710/00 (20130101)
C12N 2750/14143 (20130101)

Enzymes
C12Y 401/01015 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11472868 Diskin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
APPLICANT(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California);  THE ROCKEFELLER UNIVERSITY (New York, New York)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California);  THE ROCKEFELLER UNIVERSITY (New York, New York)
INVENTOR(S) Ron Diskin (Rehovot, Israel);  Pamela J. Bjorkman (Pasadena, California);  Michel C. Nussenzweig (New York, New York);  Johannes Scheid (New York, New York)
ABSTRACT Embodiments of the present invention are directed to compositions and methods for anti-HIV (anti-CD4 binding site) potent VRC01-like (PVL) antibodies targeted to gp120 having an amino acid substitution at a residue in the anti-CD4 binding site PVL antibody that is equivalent to Phe43 in CD4, these antibodies having improved potency and breadth.
FILED Monday, February 10, 2020
APPL NO 16/786821
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 16/1063 (20130101) Original (OR) Class
C07K 2317/55 (20130101)
C07K 2317/76 (20130101)
C07K 2317/92 (20130101)
C07K 2317/565 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2740/16111 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11472888 Herz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Joachim Herz (Austin, Texas);  Yinyuan Ding (Austin, Texas);  Xunde Xian (Austin, Texas);  Linzhang Huang (Austin, Texas);  Chieko Mineo (Austin, Texas);  Philip Shaul (Austin, Texas);  Laurent Calvier (Austin, Texas)
ABSTRACT The present invention provides methods and compositions for treating atherosclerosis in a subject comprising the use of therapeutic compounds to reduce Reelin in the circulation of the subject, thereby reducing the adhesion of leukocytes to the vascular wall. The invention also provides methods and compositions for reducing leukocyte adhesion to the vascular wall in a subject.
FILED Thursday, May 14, 2020
APPL NO 15/931976
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0276 (20130101)
A01K 2217/15 (20130101)
A01K 2217/075 (20130101)
A01K 2217/206 (20130101)
A01K 2227/105 (20130101)
A01K 2267/0375 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 31/713 (20130101)
A61K 38/00 (20130101)
A61K 45/06 (20130101)
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/10 (20180101)

Peptides
C07K 16/18 (20130101)
C07K 16/40 (20130101) Original (OR) Class
C07K 2317/21 (20130101)
C07K 2317/24 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1137 (20130101)
C12N 15/1138 (20130101)
C12N 2310/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11473055 Maghodia et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Glycobac, LLC (Laramie, Wyoming)
ASSIGNEE(S) GLYCOBAC, LLC (Laramie, Wyoming)
INVENTOR(S) Ajay Maghodia (Laramie, Wyoming);  Christoph Geisler (Laramie, Wyoming);  Donald Jarvis (Laramie, Wyoming)
ABSTRACT The current teachings are directed to virus free cells lines derived from virus-contaminated starting material, such as an organism or a cell line. Methods for obtaining virus free cell lines obtained from virus-contaminated starting material are also provided. Exemplary virus free cell lines include: cell lines derived from a Spodoptera frugiperda cell line contaminated with Sf-rhabdovirus, wherein the cell lines lack Sf-rhabdovirus; and cell lines derived from a Trichoplusia ni cell line contaminated with an alphanodavirus, wherein the cell line lacks an alphanodavirus.
FILED Tuesday, November 01, 2016
APPL NO 15/772476
ART UNIT 1699 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0601 (20130101) Original (OR) Class
C12N 7/00 (20130101)
C12N 15/00 (20130101)
C12N 2500/40 (20130101)
C12N 2710/14151 (20130101)
C12N 2760/20011 (20130101)
C12N 2770/30011 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11473066 Voziyanov
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Louisiana Tech Research Corporation (Ruston, Louisiana)
ASSIGNEE(S)
INVENTOR(S) Yuri Voziyanov (Ruston, Louisiana)
ABSTRACT The present invention provides chimeric Flp-TAL recombinases, as well as nucleic acids, and methods for the use of the chimeric Flp-TAL recombinases for site-specific alteration of a target sequence in cells.
FILED Saturday, November 09, 2019
APPL NO 16/679201
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 2319/09 (20130101)
C07K 2319/80 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1241 (20130101) Original (OR) Class
C12N 15/907 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11473070 Zhan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) University of Kentucky Research Foundation (Lexington, Kentucky)
ASSIGNEE(S) University of Kentucky Research Foundation (Lexington, Kentucky)
INVENTOR(S) Chang-Guo Zhan (Lexington, Kentucky);  Fang Zheng (Lexington, Kentucky)
ABSTRACT The presently-disclosed subject matter describes fusion proteins comprising butyrylcholinesterase (BChE) having an improved production yield and biological half-life and nucleotides encoding the same.
FILED Monday, December 21, 2020
APPL NO 17/129736
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 2319/30 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/18 (20130101) Original (OR) Class

Enzymes
C12Y 301/01008 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11473080 Kay et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Brian K. Kay (Chicago, Illinois);  Kevin T. Gorman (Chicago, Illinois);  Renhua Huang (Rockville, Maryland)
ABSTRACT A combined Kunkel mutagenesis and phage-display method for producing bivalent binding agents is provided.
FILED Monday, November 05, 2018
APPL NO 16/180290
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 16/005 (20130101)
C07K 16/40 (20130101)
C07K 2317/31 (20130101)
C07K 2317/92 (20130101)
C07K 2318/20 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
C12N 15/1037 (20130101) Original (OR) Class
C12N 15/1058 (20130101)
C12N 2795/14143 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11473084 Davidson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania)
INVENTOR(S) Beverly L. Davidson (North Liberty, Iowa);  Alejandro Mas Monteys (Philadelphia, Pennsylvania);  Shauna Ebanks (Claymont, Delaware)
ABSTRACT Compositions and methods are provided for the inhibition, treatment and/or prevention of Huntington's disease and related disorders.
FILED Tuesday, October 11, 2016
APPL NO 15/766549
ART UNIT 1699 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 48/005 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/00 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/66 (20130101)
C12N 15/88 (20130101)
C12N 15/102 (20130101)
C12N 15/113 (20130101) Original (OR) Class
C12N 15/861 (20130101)
C12N 2310/20 (20170501)
C12N 2330/51 (20130101)
C12N 2800/80 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11473108 Doudna et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Regents of the University of California (Oakland, California);  University of Vienna (Vienna, Austria);  Emmanuelle Charpentier (Berlin, Germany)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  University of Vienna (Vienna, Austria);  Emmanuelle Charpentier (Berlin, Germany)
INVENTOR(S) Jennifer A. Doudna (Berkeley, California);  Martin Jinek (Berkeley, California);  Krzysztof Chylinski (Vienna, Austria);  Emmanuelle Charpentier (Berlin, Germany)
ABSTRACT The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a polypeptide associated with the target DNA. The present disclosure further provides site-specific modifying polypeptides. The present disclosure further provides methods of site-specific modification of a target DNA and/or a polypeptide associated with the target DNA The present disclosure provides methods of modulating transcription of a target nucleic acid in a target cell, generally involving contacting the target nucleic acid with an enzymatically inactive Cas9 polypeptide and a DNA-targeting RNA. Kits and compositions for carrying out the methods are also provided. The present disclosure provides genetically modified cells that produce Cas9; and Cas9 transgenic non-human multicellular organisms.
FILED Thursday, March 24, 2022
APPL NO 17/703845
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques
A01H 6/4684 (20180501)

Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/027 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 38/465 (20130101)
A61K 48/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/63 (20130101)
C12N 15/70 (20130101)
C12N 15/90 (20130101)
C12N 15/102 (20130101)
C12N 15/111 (20130101)
C12N 15/113 (20130101)
C12N 15/746 (20130101)
C12N 15/902 (20130101)
C12N 15/907 (20130101) Original (OR) Class
C12N 2310/11 (20130101)
C12N 2310/13 (20130101)
C12N 2310/14 (20130101)
C12N 2310/20 (20170501)
C12N 2310/31 (20130101)
C12N 2310/32 (20130101)
C12N 2310/33 (20130101)
C12N 2310/531 (20130101)
C12N 2310/3519 (20130101)
C12N 2800/80 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101)

Enzymes
C12Y 301/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11473129 Cai et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
NIH Office of the Director (NIHOD)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Long Cai (Pasadena, California);  Eric Lubeck (Pasadena, California);  Timur Zhiyentayev (Pasadena, California);  Ahmet Coskun (Pasadena, California);  Ting-Fang He (Pasadena, California);  Chang Ho Sohn (Pasadena, California);  Sheel Shah (Pasadena, California)
ABSTRACT The present invention, among other things, provides technologies for detecting and/or quantifying nucleic acids in cells, tissues, organs or organisms. In some embodiments, through sequential barcoding, the present invention provides methods for high-throughput profiling of a large number of targets, such as transcripts and/or DNA loci.
FILED Monday, September 16, 2019
APPL NO 16/572511
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1065 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6841 (20130101) Original (OR) Class
C12Q 1/6841 (20130101)
C12Q 2537/143 (20130101)
C12Q 2565/102 (20130101)
C12Q 2565/601 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6428 (20130101)
G01N 21/6458 (20130101)
G01N 2201/10 (20130101)
G01N 2201/068 (20130101)

Optical Elements, Systems, or Apparatus
G02B 21/06 (20130101)
G02B 21/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11473139 Church et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) George M. Church (Brookline, Massachusetts);  Richard C. Terry (Carlisle, Massachusetts);  Frederic Vigneault (Ashland, Massachusetts)
ABSTRACT A method of sequencing nucleic acids is provided using DNA origami as a barcode for a nucleic acid probe.
FILED Thursday, March 26, 2020
APPL NO 16/830372
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6869 (20130101)
C12Q 1/6869 (20130101)
C12Q 1/6869 (20130101)
C12Q 1/6874 (20130101) Original (OR) Class
C12Q 2525/161 (20130101)
C12Q 2533/107 (20130101)
C12Q 2563/179 (20130101)
C12Q 2563/185 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11473141 Meagher et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Robert Meagher (Mountain House, California);  Chung-Yan Koh (Arlington, Virginia);  Yooli Kim Light (Pleasanton, California);  Cameron Scott Ball (Los Altos, California)
ABSTRACT The present invention relates to probes and primers beneficial for conducting amplification assays, such as those including loop-mediated isothermal amplification reactions. Also described herein are methods for detecting targets using such probes and/or primers.
FILED Tuesday, June 16, 2020
APPL NO 16/903075
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6818 (20130101)
C12Q 1/6876 (20130101) Original (OR) Class
C12Q 2600/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11473146 Muir et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Peter Muir (Madison, Wisconsin);  Susannah Sample (Madison, Wisconsin);  John Svaren (Madison, Wisconsin)
ABSTRACT Methods for diagnosing propensity to exhibit acquired peripheral neuropathy in dogs are described. The methods and kits test dogs for presence of a disease-associated genomic variant. Presence of the genomic variant indicates an increased likelihood of the dog developing an acquired peripheral neuropathy. This information can be used to guide preemptive clinical treatment of the animal for peripheral neuropathy and to choose dogs for selective breeding programs.
FILED Friday, January 17, 2020
APPL NO 16/745608
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101) Original (OR) Class
C12Q 2600/156 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11473826 Closs et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Mitegen, LLC (Ithaca, New York)
ASSIGNEE(S) MiTeGen, LLC (Ithaca, New York)
INVENTOR(S) David Closs (Freeville, New York);  Stephen Hollabaugh (Ithaca, New York);  Robert E. Thorne (Ithaca, New York);  Robert Newman (Groton, New York);  Benjamin A. Apker (Ithaca, New York)
ABSTRACT A cryogenic cooling manifold and methods incorporating a cryogenic cooling manifold for managing the gas layer(s) above a liquid cryogen to control cooling temperature-time profiles and ice formation for microliter and smaller samples that are plunged through the gas and into the liquid cryogen.
FILED Wednesday, July 27, 2016
APPL NO 15/220868
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 1/0252 (20130101)

Refrigerators; Cold Rooms; Ice-boxes; Cooling or Freezing Apparatus Not Otherwise Provided for
F25D 3/10 (20130101) Original (OR) Class
F25D 2400/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11474005 Volckens et al.
FUNDED BY
Department of Health and Human Services (HHS)
Centers for Disease Control and Prevention (CDC)
National Institute for Occupational Safety and Health (NIOSH)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S) Colorado State University Research Foundation (Fort Collins, Colorado);  Access Sensor Technologies LLC (Fort Collins, Colorado)
ASSIGNEE(S) Colorado State University Research Foundation (Fort Collins, Colorado);  Access Sensor Technologies LLC (Fort Collins, Colorado)
INVENTOR(S) John Volckens (Fort Collins, Colorado);  Daniel D. Miller-Lionberg (Denver, Colorado);  Josephine Hofstetter (Commerce City, Colorado);  Casey William Quinn (Olympia, Washington);  Ellison Carter (Fort Collins, Colorado);  David Leith (Chapel Hill, North Carolina)
ABSTRACT A portable sampling device includes a sampling housing at least partially enclosing an inner chamber; at least one pumping element disposed within the inner chamber and configured to facilitate airflow through the device; and at least one gas sensor disposed within the inner chamber and configured to detect and/or characterize one or more gases in the airflow.
FILED Thursday, May 23, 2019
APPL NO 17/057256
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/24 (20130101)
G01N 1/2205 (20130101)
G01N 1/2214 (20130101)
G01N 1/2273 (20130101) Original (OR) Class
G01N 2001/2223 (20130101)
G01N 2001/2276 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11474023 Mutlu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Baris R. Mutlu (Cambridge, Massachusetts);  Jon F. Edd (Wakefield, Massachusetts);  Mehmet Toner (Charlestown, Massachusetts)
ABSTRACT This disclosure provides systems and methods to extend the capabilities of inertial and/or viscoelastic focusing in channels, such as microchannels. The new systems and methods can be integrated with existing microfluidic devices for inertial and/or viscoelastic manipulation of particles that have defied prior attempts, enabling a variety of applications in clinical diagnosis. The particles, e.g., bioparticles and cells, focus into streamlines in the same way and in the same locations as in existing inertial and viscoelastic focusing systems, but at much lower particle Reynolds numbers, much lower shear stress, over much shorter distances, and at lower driving pressures and/or flow rates.
FILED Monday, June 04, 2018
APPL NO 16/617114
ART UNIT 2877 — Optics
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 2200/0652 (20130101)
B01L 2400/04 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/1404 (20130101)
G01N 15/1459 (20130101) Original (OR) Class
G01N 15/1484 (20130101)
G01N 2015/1413 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11474097 An et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (Baltimore, Maryland);  NATIONAL INSTITUTES OF HEALTH (Bethesda, Maryland)
ASSIGNEE(S) UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (Baltimore, Maryland);  NATIONAL INSTITUTES OF HEALTH (Bethesda, Maryland)
INVENTOR(S) Songon An (Ellicott City, Maryland);  Danielle L. Schmitt (San Diego, California);  James Inglese (Bethesda, Maryland);  Patricia Dranchak (Gaithersburg, Maryland)
ABSTRACT A cell-based quantitative high-throughput screening assay to monitor the formation of PFK1-mEGFP clusters by the action of small molecules to identify small molecules that promote intracellular PFK1 clustering in a cell cycle-dependent manner and may be used to treat cancer.
FILED Wednesday, June 26, 2019
APPL NO 16/452767
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/85 (20130101)

Enzymes
C12Y 207/01011 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6428 (20130101)
G01N 33/5011 (20130101)
G01N 33/5035 (20130101) Original (OR) Class
G01N 2021/6439 (20130101)
G01N 2333/91215 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11474098 Marx et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York);  THE NEW YORK PRESBYTERIAN HOSPITAL (New York, New York)
INVENTOR(S) Steven Marx (Scarsdale, New York);  Alexander Kushnir (Passaic, New Jersey);  Lin Yang (New York, New York);  Alex Katchman (New York, New York);  Henry M. Colecraft (New York, New York)
ABSTRACT The present invention provides, inter alia, methods for identifying a candidate agent that can treat or ameliorate the effects of a heart condition caused by the effects of abnormal beta-adrenergic receptor activation on calcium levels in cardiomyocytes in a subject. Compositions that include the candidate agents identified by the methods disclosed, and methods of treating or ameliorating the effects of a heart condition in a subject by administering to the subject the candidate agents identified by the methods disclosed, are also provided.
FILED Thursday, December 20, 2018
APPL NO 16/228433
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/4422 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/00 (20180101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5041 (20130101) Original (OR) Class
G01N 33/6872 (20130101)
G01N 2500/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11474105 Young et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina);  Upstate Affiliate Organization (Greenville, South Carolina);  Board of Trustees of Michigan State University (East Lansing, Michigan)
ASSIGNEE(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina);  Upstate Affiliate Organization (Greenville, South Carolina);  Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S) Steven L. Young (Durham, North Carolina);  Bruce Arthur Lessey (Greenville, South Carolina);  Jae Wook Jeong (Grand Rapids, Michigan)
ABSTRACT The present invention provides a method of diagnosing endometriosis and/or infertility in a subject, comprising: a) obtaining a sample from the subject; b) detecting a level of expression of a SIRT1 gene and/or protein in the sample; c) detecting a level of expression of a BCL6 gene and/or protein in the sample; d) comparing the level of expression detected in (b) with the level of expression of a SIRT1 gene and/or protein in a sample obtained from a control subject or a population of control subjects; e) comparing the level of expression detected in (c) with the level of expression of a BCL6 gene and/or protein in a sample obtained from a control subject or a population of control subjects; and f) diagnosing the subject as having infertility when the subject has a level of expression of the SIRT1 gene and/or protein greater than the level of expression of the SIRT1 gene and/or protein of the control subject or population of control subjects and also has a level of expression of the BCL6 gene and/or protein that is greater than the level of expression of the BCL6 gene and/or protein of the control subject or population of control subjects.
FILED Friday, March 31, 2017
APPL NO 16/090066
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 16/40 (20130101)
C07K 2317/34 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/689 (20130101)
G01N 33/6872 (20130101)
G01N 33/57449 (20130101) Original (OR) Class
G01N 2333/98 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11474106 Henderson et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) ACCELERATED MEDICAL DIAGNOSTICS, INC. (Berkeley, California);  LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California);  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
INVENTOR(S) Paul Henderson (Berkeley, California);  George D. Cimino (Lafayette, California);  Chong-Xian Pan (Davis, California);  Ralph William de Vere White (Sacramento, California);  Maike Zimmermann (Davis, California);  Kenneth W. Turteltaub (Livermore, California)
ABSTRACT The invention relates to methods, systems and kits for determining therapeutic effectiveness or toxicity of cancer-treating compounds that incorporate into or bind to DNA. In particular, the invention is directed to methods, systems and kits for predicting a patient's treatment outcome after administration of a microdose of therapeutic composition to the patient. The methods provides physicians with a diagnostic tool to segregate cancer patients into differential populations that have a higher or lower chance of responding to a particular therapeutic treatment.
FILED Thursday, July 07, 2016
APPL NO 15/742454
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/28 (20130101)
A61K 31/395 (20130101)
A61K 31/555 (20130101)
A61K 31/555 (20130101)
A61K 31/7068 (20130101)
A61K 31/7068 (20130101)
A61K 33/24 (20130101)
A61K 33/243 (20190101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/60 (20130101)
G01N 33/96 (20130101)
G01N 33/5308 (20130101)
G01N 33/6848 (20130101)
G01N 33/57484 (20130101) Original (OR) Class
G01N 2800/52 (20130101)
G01N 2800/56 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11474531 Reiserer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Institute of Child Health and Human Development (NICHD)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
APPLICANT(S) VANDERBILT UNIVERSITY (Nashville, Tennessee)
ASSIGNEE(S) VANDERBILT UNIVERSITY (Nashville, Tennessee)
INVENTOR(S) Ronald S. Reiserer (Nashville, Tennessee);  John P. Wikswo (Brentwood, Tennessee)
ABSTRACT A robot for transporting a biodevice from one place to another place, comprising a body for carrying the biodevice; a driving assembly for driving the body in omnidirectional motion; a sensing unit for sensing at least a position and orientation of the body; and a control unit coupled to the driving assembly and the sensing unit for generating one or more control signals based on at least the sensed position and orientation of the body to drive the driving assembly so as to move the body to a desired place and to arrive with the correct orientation.
FILED Wednesday, January 19, 2022
APPL NO 17/578779
ART UNIT 1799 — Optics
CURRENT CPC
Vehicle Wheels; Castors; Axles for Wheels or Castors; Increasing Wheel Adhesion
B60B 19/003 (20130101)

Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles
B60L 53/12 (20190201)

Apparatus for Enzymology or Microbiology;
C12M 23/44 (20130101)
C12M 23/50 (20130101)
C12M 23/52 (20130101)
C12M 29/10 (20130101)
C12M 41/48 (20130101)

Systems for Controlling or Regulating Non-electric Variables
G05D 1/0225 (20130101) Original (OR) Class
G05D 1/0291 (20130101)
G05D 1/0891 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11474800 Jain et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Vignet Incorporated (Fairfax, Virginia)
ASSIGNEE(S) VigNet Incorporated (Fairfax, Virginia)
INVENTOR(S) Praduman Jain (Fairfax, Virginia);  Dave Klein (Oakton, Virginia);  Neeta Jain (Fairfax, Virginia);  Yue Cao (Vienna, Virginia)
ABSTRACT In some implementations, a user interface for designing a health management module is provided by a server system. The user interface identifies a plurality of health management templates. The server system initially receives data indicating a user input received through the user interface that selects one of the plurality of module templates. The server system also receives customization parameters that customize the selected module template for a particular organization. The server system then generates a customized health management module for the particular organization based on the selected template and the customization parameters. The server system finally publishes the customized health management module for the particular organization that includes instructions configuring an application provided by a third-party application store.
FILED Thursday, July 30, 2020
APPL NO 16/942822
ART UNIT 2192 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 3/04817 (20130101)
G06F 3/04842 (20130101)
G06F 8/38 (20130101)
G06F 8/60 (20130101) Original (OR) Class
G06F 8/61 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 10/20 (20180101)
G16H 10/60 (20180101)
G16H 40/40 (20180101)
G16H 40/63 (20180101)
G16H 40/67 (20180101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 41/0803 (20130101)
H04L 67/01 (20220501)
H04L 67/06 (20130101)
H04L 67/025 (20130101)
H04L 67/34 (20130101)
H04L 67/53 (20220501)
H04L 67/125 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11475979 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Xuemeng Zhang (Houston, Texas);  Zheng Fang (Houston, Texas);  Ruojia Wu (Houston, Texas);  Wei Duan (Beijing, China PRC);  David Zhang (Houston, Texas);  William Marsh Rice University (Houston, Texas)
ASSIGNEE(S) William Marsh Rice University (Houston, Texas)
INVENTOR(S) Xuemeng Zhang (Houston, Texas);  Zheng Fang (Houston, Texas);  Ruojia Wu (Houston, Texas);  Wei Duan (Beijing, China PRC);  David Zhang (Houston, Texas)
ABSTRACT Embodiments of methods, systems, and tangible non-transitory computer readable medium having instructions are presented. A method includes calculating a plurality of feature values for a number of bioinformatic features of the desired hybridization reaction; and calculating distances between the plurality of feature values and corresponding database rate constant values stored in a database, the database comprising a plurality of hybridization reactions having known rate constants. The method additionally includes calculating a weighted average of a logarithm of the database rate constant values, with larger weights assigned to value instances having values lower in distance to the plurality of feature values of the desired hybridization reaction; and providing the weighted average as a predicted logarithm of the rate constant of the desired hybridization reaction.
FILED Wednesday, June 07, 2017
APPL NO 16/308346
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 25/00 (20190201) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11477410 Harfouche et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
APPLICANT(S) Ramona Optics Inc. (Durham, North Carolina)
ASSIGNEE(S) Ramona Optics Inc. (Durham, North Carolina)
INVENTOR(S) Mark Harfouche (Durham, North Carolina);  Jaehee Park (Durham, North Carolina);  Colin Cooke (Durham, North Carolina);  Gregor Horstmeyer (Durham, North Carolina);  Veton Saliu (Durham, North Carolina)
ABSTRACT A method to capture microscopy images from multiple image sensors and to relay them to one or more central processing units while minimizing delay in image capture can include the co-optimization of image acquisition hardware, data aggregation digital logic, firmware, and integration with data post processing on the central processing units. The methods can include organizing the incoming image data into data packets containing partial image frames, together with configuring the central processing units to be capable of analyzing the received partial image frames. The quick analysis of the images, e.g., on the partial image frames, can allow the computational system to rapidly respond to the captured images, such as to provide feed back on the captured images before the next images are to be captured.
FILED Monday, January 25, 2021
APPL NO 17/157924
ART UNIT 2484 — Recording and Compression
CURRENT CPC
Pictorial Communication, e.g Television
H04N 5/77 (20130101) Original (OR) Class
H04N 5/91 (20130101)
H04N 5/232 (20130101)
H04N 5/247 (20130101)
H04N 7/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11477411 Harfouche et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
APPLICANT(S) Ramona Optics Inc. (Durham, North Carolina)
ASSIGNEE(S) Ramona Optics inc. (Durham, North Carolina)
INVENTOR(S) Mark Harfouche (Durham, North Carolina);  Jaehee Park (Durham, North Carolina);  Colin Cooke (Durham, North Carolina);  Gregor Horstmeyer (Durham, North Carolina);  Veton Saliu (Durham, North Carolina)
ABSTRACT A method to capture microscopy images from multiple image sensors and to relay them to one or more central processing units while minimizing delay in image capture can include the co-optimization of image acquisition hardware, data aggregation digital logic, firmware, and integration with data post processing on the central processing units. The methods can include organizing the incoming image data into data packets containing partial image frames, together with configuring the central processing units to be capable of analyzing the received partial image frames. The quick analysis of the images, e.g., on the partial image frames, can allow the computational system to rapidly respond to the captured images, such as to provide feed back on the captured images before the next images are to be captured.
FILED Monday, January 25, 2021
APPL NO 17/157928
ART UNIT 2484 — Recording and Compression
CURRENT CPC
Pictorial Communication, e.g Television
H04N 5/04 (20130101)
H04N 5/77 (20130101) Original (OR) Class
H04N 5/91 (20130101)
H04N 5/247 (20130101)
H04N 7/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 11471135 Park et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Small Business Technology Transfer (STTR)
APPLICANT(S) Intelligent Fiber Optic Systems, Inc. (Santa Clara, California)
ASSIGNEE(S) Intelligent Fiber Optic Systems, Inc. (San Jose, California)
INVENTOR(S) Yong-Lae Park (Stanford, California);  Richard James Black (Menlo Park, California);  Behzad Moslehi (Los Altos, California);  Mark R. Cutkosky (Stanford, California);  Santhi Elayaperumal (Stanford, California);  Bruce Daniel (Stanford, California);  Alan Yeung (Stanford, California);  Vahid Sotoudeh (Los Altos, California)
ABSTRACT A biopsy needle has a central axis and includes one or more sensing regions, each sensing region formed by a plurality of sensing optical fibers located over a particular extent of said central axis and inside the outer shell of the needle. The sensing optical fibers are coupled to a wavelength interrogator. A steerable catheter has a central axis and outer shell, the outer shell coupled to a plurality of optical fibers in sensing regions and actuation regions, the sensing regions formed over particular extents of the central axis by bonding gratings to the inner surface of the outer shell, and the actuation regions formed by coupling optical energy into shape memory alloys bonded to the outer shell.
FILED Monday, February 11, 2019
APPL NO 16/271883
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 10/0233 (20130101) Original (OR) Class
A61B 18/1492 (20130101)
A61B 90/06 (20160201)
A61B 2017/00057 (20130101)
A61B 2017/00867 (20130101)
A61B 2034/2061 (20160201)
A61B 2090/064 (20160201)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 25/0043 (20130101)
A61M 25/0105 (20130101)
A61M 25/0133 (20130101)
A61M 25/0158 (20130101)
A61M 2025/0166 (20130101)
A61M 2205/0266 (20130101)
A61M 2205/3306 (20130101)

Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 1/246 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471477 Clarke et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Chan Zuckerberg Biohub, Inc. (San Francisco, California);  The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) Chan Zuckerberg Biohub, Inc. (San Francisco, California);  The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Michael F. Clarke (San Francisco, California);  Robert W. Hsieh (San Francisco, California)
ABSTRACT The invention is directed to methods of treating TNBC in a patient by administering to the patient an agent that inhibits the expression or activity of cyclin-dependent kinase 19 (CDK19). In some embodiments, the agent may be a small molecule inhibitor, a polynucleotide (e.g., shRNA. siRNA), or a protein (e.g., an antibody). In some embodiments, the agent does not inhibit the activity or expression of CDK8.
FILED Tuesday, September 18, 2018
APPL NO 16/648088
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/713 (20130101) Original (OR) Class
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)
C12N 2310/14 (20130101)
C12N 2310/531 (20130101)
C12N 2320/30 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57415 (20130101)
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471557 Stewart
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah)
ASSIGNEE(S) UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah)
INVENTOR(S) Russell J. Stewart (Salt Lake City, Utah)
ABSTRACT Described herein are fluid complex coacervates that produce solid adhesives in situ. Oppositely charged polyelectrolytes were designed to form fluid adhesive complex coacervates at ionic strengths higher than the ionic strength of the application site, but an insoluble adhesive solid or gel at the application site. When the fluid, high ionic strength adhesive complex coacervates are introduced into the lower ionic strength application site, the fluid complex coacervate is converted to a an adhesive solid or gel as the salt concentration in the complex coacervate equilibrates to the application site salt concentration. In one embodiment, the fluid complex coacervates are designed to solidify in situ at physiological ionic strength and have numerous medical applications. In other aspects, the fluid complex coacervates can be used in aqueous environment for non-medical applications.
FILED Friday, June 26, 2020
APPL NO 16/912830
ART UNIT 1699 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/0043 (20130101)
A61K 49/0054 (20130101)
A61K 49/0073 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 24/02 (20130101)
A61L 24/10 (20130101)
A61L 24/0015 (20130101)
A61L 24/0031 (20130101)
A61L 24/0042 (20130101)
A61L 24/043 (20130101)
A61L 24/043 (20130101)
A61L 24/046 (20130101) Original (OR) Class
A61L 24/104 (20130101)
A61L 2300/44 (20130101)
A61L 2300/416 (20130101)
A61L 2430/02 (20130101)
A61L 2430/36 (20130101)

Compositions of Macromolecular Compounds
C08L 89/00 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 5/1668 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471939 Xia et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Younan Xia (Seattle, Washington);  Yugang Sun (Champaign, Illinois)
ABSTRACT Methods for forming nanostructures of various shapes are disclosed. Nanocubes, nanowires, nanopyramids and multiply twinned particles of silver may by formed by combining a solution of silver nitrate in ethylene glycol with a solution of poly(vinyl pyrrolidone) in ethylene glycol. Hollow nanostructures may be formed by reacting a solution of solid nanostructures comprising one of a first metal and a first metal alloy with a metal salt that can be reduced by the first metal or first metal alloy. Nanostructures comprising a core with at least one nanoshell may be formed by plating a nanostructure and reacting the plating with a metal salt.
FILED Monday, July 01, 2019
APPL NO 16/459407
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/0003 (20130101)
B22F 1/0007 (20130101) Original (OR) Class
B22F 1/054 (20220101)
B22F 1/062 (20220101)
B22F 1/065 (20220101)
B22F 1/0547 (20220101)
B22F 1/0549 (20220101)
B22F 1/0553 (20220101)
B22F 1/0655 (20220101)
B22F 9/24 (20130101)
B22F 2009/245 (20130101)
B22F 2301/255 (20130101)
B22F 2304/05 (20130101)
B22F 2998/00 (20130101)
B22F 2998/00 (20130101)
B22F 2998/00 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 977/896 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471985 Tindal
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Mitchell Tindal (Hartland, Wisconsin)
ABSTRACT A tripod jack cylinder removal tool including a lifting eyebolt attached through an up flange and further through and up flange aperture to a lock nut. The flange is secured to a pipe at a pipe top end, the pipe further having a bottom end wherein a down flange having a down flange aperture is attached to the pipe and a bolt having threads protrudes through a down flange aperture.
FILED Thursday, February 17, 2022
APPL NO 17/674278
ART UNIT 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools
B23P 19/04 (20130101) Original (OR) Class

Hoisting, Lifting, Hauling or Pushing, Not Otherwise Provided For, e.g Devices Which Apply a Lifting or Pushing Force Directly to the Surface of a Load
B66F 13/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11472127 Rice et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S) Kineticure, LLC (Miamisburg, Ohio)
ASSIGNEE(S)
INVENTOR(S) Jason P. Rice (Dayton, Ohio);  Mark C. Cridge (Miamisburg, Ohio);  Christopher D. Hemmelgarn (South Charleston, Ohio);  Patrick J. Hood (Bellbrook, Ohio);  Tat Hung Tong (Bellbrook, Ohio)
ABSTRACT Systems for positioning and bonding a nutplate to a substrate having an aperture include a nutplate engagement fixture and a temperature sensor retention fixture. The nutplate engagement fixture includes a rigid tube and an elastomeric tube engaged with the rigid tube, the elastomeric tube having an elongated tube sized to provide a friction fit with the aperture and retain the elastomeric tube within the aperture. The rigid tube is operable to engage the nutplate at one end and the elastomeric tube is configured to anchor the nutplate engagement fixture at the aperture and secure the nutplate in contact with the substrate. The temperature sensor retention fixture includes a fixture body sized and configured to engage with the nutplate and at least one passageway within the fixture body sized and configured to allow a temperature sensor to be inserted or embedded therein with an end proximal a surface of the nutplate.
FILED Wednesday, March 11, 2020
APPL NO 16/815287
ART UNIT 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 65/76 (20130101)
B29C 65/565 (20130101)
B29C 65/7844 (20130101) Original (OR) Class
B29C 66/91211 (20130101)

Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing
F16B 37/14 (20130101)
F16B 37/043 (20130101)
F16B 37/044 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11472520 Cohen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Information Warfare Center (NIWC)
Naval Information Warfare Center Pacific (NIWCPACIFIC)
APPLICANT(S) United States of America as represented by the Secretary of the Navy (San Diego, California)
ASSIGNEE(S) United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Nathan David Cohen (Encinitas, California);  Nathan Todd Miller (San Diego, California)
ABSTRACT A mooring system comprising: a ballast platform; and a chain comprising a plurality of links that are pivotally connected to each other via parallel pivot pins such that the chain is configured to not rotate about a vertical axis that is orthogonal to axes of rotation of the pivot pins, wherein the chain has proximal and distal ends, and wherein the proximal end is attached to a top of the ballast platform and the distal end is configured to be attached to a buoyant object.
FILED Wednesday, December 02, 2020
APPL NO 17/109290
ART UNIT 3617 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Ships or Other Waterborne Vessels; Equipment for Shipping
B63B 21/20 (20130101)
B63B 39/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11472750 Garcia
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Space Command (AFSPC)
Space and Missile Systems Center (SMC)
APPLICANT(S) Northrop Grumman Systems Corporation (Falls Church, Virginia)
ASSIGNEE(S) Northrop Grumman Systems Corporation (Falls Church, Virginia)
INVENTOR(S) Benjamin W. C. Garcia (Tremonton, Utah)
ABSTRACT A barrier coating resin formulation comprising at least one polycarbosilane preceramic polymer, at least one organically modified silicon dioxide preceramic polymer, at least one filler, and at least one solvent. A barrier coating comprising a reaction product of the at least one polycarbosilane preceramic polymer and the at least one organically modified silicon dioxide preceramic polymer and the at least one filler is also disclosed, as are articles comprising the barrier coating, rocket motors comprising the barrier coating, and methods of forming the articles.
FILED Monday, August 27, 2018
APPL NO 16/113257
ART UNIT 1759 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/48 (20130101)
C04B 35/565 (20130101)
C04B 35/62222 (20130101)
C04B 41/009 (20130101)
C04B 41/85 (20130101) Original (OR) Class
C04B 41/87 (20130101)
C04B 41/5042 (20130101)
C04B 41/5059 (20130101)
C04B 2235/428 (20130101)
C04B 2235/483 (20130101)
C04B 2235/3244 (20130101)
C04B 2235/3418 (20130101)
C04B 2235/3813 (20130101)
C04B 2235/3826 (20130101)
C04B 2235/9669 (20130101)

Jet-propulsion Plants
F02K 9/974 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11473104 Krom et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  Trustees of Boston University (Boston, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  Trustees of Boston University (Boston, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Russell-John Krom (Boston, Massachusetts);  James J. Collins (Newton, Massachusetts);  Prerna Saluja Bhargava (Watertown, Massachusetts);  Michael Andrew Lobritz (Newton, Massachusetts)
ABSTRACT Provided herein, in some embodiments, are engineered phagemids that comprise at least one synthetic genetic circuit, wherein the at least one synthetic genetic circuit comprises gene sequences encoding at least one non-lytic antimicrobial peptides (AMPs) and/or antibacterial toxin proteins, a stable origin of replication, and a bacteriophage-packaging signal, wherein the engineered phagemid does not comprise some or all gene sequences encoding bacteriophage proteins required for assembly of a bacteriophage particle.
FILED Friday, December 04, 2015
APPL NO 15/780668
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/76 (20130101)

Peptides
C07K 14/245 (20130101)
C07K 14/461 (20130101)
C07K 14/463 (20130101)
C07K 14/43572 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/63 (20130101)
C12N 15/70 (20130101)
C12N 15/74 (20130101)
C12N 15/86 (20130101) Original (OR) Class
C12N 2795/14132 (20130101)
C12N 2795/14143 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11473128 Pennathur et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Alveo Technologies, Inc. (Alameda, California);  The Regents of the University of California (Oakland, California)
ASSIGNEE(S) ALVEO Technologies, Inc. (Alameda, California);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Sumita Pennathur (Goleta, California);  Peter Joseph Crisalli (Goleta, California);  Ronald Phillip Chiarello (Lafayette, California)
ABSTRACT Embodiments provide detection systems and methods for detecting the presence of a nucleic acid in one or more samples. In a detection method, a sample and one or more nucleic acid probes are introduced into a channel. A first potential difference is applied across the length of the channel in a first direction, and a first electrical property value is detected. Subsequently, a second potential difference is applied across the length of the channel in a second opposite direction, and a second electrical property value is detected. Presence or absence of a nucleic acid in the channel is determined based on a comparison between the first and second electrical property values.
FILED Wednesday, March 11, 2020
APPL NO 16/815404
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5027 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6825 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/06 (20130101)
G01N 27/44791 (20130101)
G01N 33/48707 (20130101)
G01N 33/48721 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11473500 Cicchini
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Nicholas P. Cicchini (Vail, Arizona)
ABSTRACT A method of reducing low-energy flow in a flight vehicle engine includes an isolator of the engine having a swept-back wedge to improve flow mixing. The wedge includes forward shock-anchoring locations, such as edges or rapidly-curved portions, that anchor oblique shocks in situations where the isolator has sufficient back pressure. The swept-back wedge may also create swept oblique shocks along its length. Boundary layer flow streamlines are diverted running parallel to or parallel but moving outward conically to the swept-wedge leading edge moving outboard and upward. The non-viscous flow outside the boundary layer is processed through the swept-back ramp shock and diverted outboard and upward as well. The outboard aft portion of the wedge at the sidewall intersection may also induce shocks and divert flow near the walls closer toward the walls and upward, and/or improve flow mixing.
FILED Wednesday, April 28, 2021
APPL NO 17/242394
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Aeroplanes; Helicopters
B64C 23/04 (20130101)
B64C 30/00 (20130101)

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 27/20 (20130101)
B64D 33/02 (20130101)
B64D 2033/026 (20130101)

Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 7/04 (20130101) Original (OR) Class

Jet-propulsion Plants
F02K 7/00 (20130101)
F02K 7/08 (20130101)
F02K 7/10 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/10 (20130101)
F05D 2220/80 (20130101)
F05D 2250/51 (20130101)

Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 10/38 (20130101)
F42B 10/42 (20130101)
F42B 15/10 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 50/60 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11473624 Taketa et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Rolls-Royce Corporation (Indianapolis, Indiana);  Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana)
ASSIGNEE(S) ROLLS-ROYCE CORPORATION (Indianapolis, Indiana);  ROLLS-ROYCE NORTH AMERICAN TECHNOLOGIES INC. (Indianapolis, Indiana)
INVENTOR(S) Jared Taketa (Indianapolis, Indiana);  Caleb Camara (Indianapolis, Indiana);  Grant Wible (Indianapolis, Indiana)
ABSTRACT A bearing lubrication system includes a bearing assembly comprising a duplex bearing including an outer ring, an inner ring positioned radially inward from the outer ring, and two sets of circumferentially distributed rolling elements between the inner and outer rings. The bearing assembly further includes a housing radially surrounding the duplex bearing and including a lubricant flow passage in fluid communication with a source of lubricant. A flow orifice is located downstream of the lubricant flow passage for jetting the lubricant into the duplex bearing. The flow orifice has an axial location between the two sets of rolling elements.
FILED Monday, May 17, 2021
APPL NO 17/322500
ART UNIT 3656 — Material and Article Handling
CURRENT CPC
Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings
F16C 19/183 (20130101)
F16C 33/60 (20130101)
F16C 33/6659 (20130101) Original (OR) Class
F16C 33/6681 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11473976 Schwab et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S) Daniel J. Schwab (Mantorville, Minnesota);  Gary S. Delp (Rochester, Minnesota);  Clifton R. Haider (Rochester, Minnesota);  Barry K. Gilbert (Rochester, Minnesota);  Nathan E. Harff (Rochester, Minnesota)
ABSTRACT Spectrophotometer system configured to characterize and/or measure spectrally (wavelength)-dependent properties of material components (such as molecular, viral, and/or bacterial analytes) associated with or of an object prior to the time when optical fingerprints of such material components start to degrade, and associated methods. System can be enhanced by a capability of selecting specific wavelengths of operation for such system to optimize cost-efficiency of the system.
FILED Tuesday, October 08, 2019
APPL NO 17/281465
ART UNIT 2886 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/027 (20130101)
G01J 3/108 (20130101)
G01J 3/0286 (20130101)
G01J 3/2803 (20130101) Original (OR) Class
G01J 2003/2866 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/35 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11473981 Roth, II et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
Naval Air Warfare Center (NAWC)
APPLICANT(S) Etegent Technologies LTD. (Cincinnati, Ohio)
ASSIGNEE(S) ETEGENT TECHNOLOGIES LTD. (Cincinnati, Ohio)
INVENTOR(S) Richard A. Roth, II (Goshen, Ohio);  Stuart J. Shelley (Cincinnati, Ohio);  Kevin Sigmund (Newtown, Ohio);  Oleg Lobkis (Mason, Ohio)
ABSTRACT A sensor with a mechanical waveguide may be characterized using test ultrasonic signals to generate a baseline signature, and the baseline signature may later be used to detect faults in the sensor.
FILED Tuesday, April 10, 2018
APPL NO 16/604431
ART UNIT 2863 — Printing/Measuring and Testing
CURRENT CPC
Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for
G01K 11/24 (20130101) Original (OR) Class

Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 1/10 (20130101)
G01L 11/06 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 29/44 (20130101)
G01N 29/075 (20130101)
G01N 29/4454 (20130101)
G01N 2291/044 (20130101)

Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for
G10K 11/24 (20130101)

Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 3/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11473983 Murray et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Research Laboratory (NRL)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretarv of the Navy (Washington, District of Columbia)
INVENTOR(S) Joseph B. Murray (Ellicott City, Maryland);  Brandon F. Redding (University Park, Maryland)
ABSTRACT A dynamic Brillouin fiber sensor that is immune to fluctuations in the power, frequency, or polarizing state of the pump and probe beams is described herein. A new measurand that combines information from the complex Stokes and anti-Stokes interactions is provided to extract the absolute Brillouin frequency shift while rejecting the majority of noise sources that may limit the performance of current slope-assisted Brillouin optical time domain analysis systems.
FILED Thursday, July 22, 2021
APPL NO 17/383263
ART UNIT 2886 — Optics
CURRENT CPC
Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for
G01K 3/00 (20130101)
G01K 11/322 (20210101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11474046 Kvryan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Surface Warfare Center (NSWC)
APPLICANT(S) Armen Kvryan (Oxnard, California);  Todd Coursey (Moorpark, California)
ASSIGNEE(S) United States of America, as Represented by the Secretary of the Navy (, None)
INVENTOR(S) Armen Kvryan (Oxnard, California);  Todd Coursey (Moorpark, California)
ABSTRACT Corrosion detection systems and methods can include at least one fiber optic cable embedded in a material having at least two layers. Two of the layers can define an interface, and the fiber optic cable can be embedded at the interface. Each fiber optic cable can have a plurality of Fiber Bragg Gratings (FBG's) formed therein at predetermined intervals. Each FBG can have a preselected geometry that can only allow a predetermined light wavelength to pass therethrough. A light source for inputting light and a photodetector can be connected to opposite exposed ends of the fiber optic cable. As corrosion occurs near an FBG, it experiences mechanical strain, which can further cause a slightly different wavelength to pass through the fiber optic cable. The change in in wavelength can be detected by the photodiode as being indicate of corrosion occurring at the site near the FBG.
FILED Wednesday, September 30, 2020
APPL NO 17/039958
ART UNIT 2886 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/8806 (20130101) Original (OR) Class
G01N 2201/088 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11474059 Shepard et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S) Thermal Wave Imaging, Inc. (Madison Heights, Michigan)
ASSIGNEE(S) Thermal Wave Imaging, Inc. (Madison Heights, Michigan)
INVENTOR(S) Steven M. Shepard (Southfield, Michigan);  Maria Frendberg Beemer (Clarkston, Michigan)
ABSTRACT A method for performing non-destructive testing using active thermography includes applying, using at least one thermal excitation device, a first excitation pulse to a workpiece; capturing, using an imaging device, a first iso-time frame of the workpiece; and determining a second excitation pulse by modifying one or more of a duration D of the first excitation pulse, an amplitude A of the first excitation pulse, or a spacing W between the first excitation pulse and the second excitation pulse. The method also includes applying, using the at least one of the thermal excitation device, the second excitation pulse to the workpiece; capturing, using the imaging device, a second iso-time frame of the workpiece; and determining a numerical fit of the first iso-time frame and the second iso-time frame.
FILED Tuesday, April 27, 2021
APPL NO 17/242000
ART UNIT 2884 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 5/10 (20130101)
G01J 5/48 (20130101)
G01J 2005/0077 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 25/72 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11474189 Hilliard, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S) BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
ASSIGNEE(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S) John E. Hilliard, Jr. (Nashua, New Hampshire);  Philip J. Haney (Merrimack, New Hampshire)
ABSTRACT A correlation and track system identifies whether a Radar warning (RW) Track contains one or more emitters by receiving a set of initial Short and Long Baseline Interferometer (SBI) (LBI) detections; receiving inertial navigational data; receiving subsequent LBI detections; determining whether the LBI detections represent one or multiple emitter(s) by designating an initial SBI conic with a multiple of its one sigma conic Direction Finding (DF) accuracy window as containing the emitter; laying down a set of grid points within the SBI conic window as possible emitters' locations; summing real and imaginary values of a residual phase in the form of a unit vector at each grid point for each LBI update; identifying whether there are one or more emitters in RW track based on whether the magnitude of a peak vector is above or below a defined threshold; and invoking geolocation algorithms based on the vector's magnitude.
FILED Wednesday, December 18, 2019
APPL NO 16/719375
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/165 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 5/0215 (20130101) Original (OR) Class
G01S 5/0236 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11474233 Hester et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
APPLICANT(S) GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia)
ASSIGNEE(S) GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia)
INVENTOR(S) Jimmy Georges Donald Hester (Atlanta, Georgia);  Emmanouil M Tentzeris (Atlanta, Georgia)
ABSTRACT A system for using thin and energy-autonomous backscatter tags and corresponding sensing nodes may operate with 24 GHz backscatter reflectarray tags having low power consumption. A digital beam steering, frequency-modulated continuous wave (FMCW) radar may be used for detection, localization, identification and communications. The tags may include environmental sensors that are used to modulate backscatter waves for data communications directed to a reader or may digitally modulate the backscatter transmissions without sensor data for independent localization of each tag in a network.
FILED Friday, December 21, 2018
APPL NO 16/956587
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/025 (20130101)
G01S 13/758 (20130101) Original (OR) Class
G01S 13/825 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 7/10168 (20130101)

Antennas, i.e Radio Aerials
H01Q 3/2647 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11474249 Gupta et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Reseach Foundation (Madison, Wisconsin)
INVENTOR(S) Mohit Gupta (Madison, Wisconsin);  Jongho Lee (Madison, Wisconsin)
ABSTRACT In accordance with some embodiments, systems, methods and media for stochastic exposure coding for continuous time-of-flight imaging are provided. In some embodiments, a method for estimating the depth of a scene is provided, comprising: stochastically selecting active slots based on a probability p; causing, during active slots, a light source to emit light modulated by a first modulation function toward a scene; causing, during active slots, an image sensor to generate a first, second, and third value based on received light from a portion of the scene and a first, second, and third demodulation function, respectively; inhibiting the light source during inactive slots; determining, for each of the active slots, depth estimates for the portion of the scene based on the first, second, and third value; and determining a depth estimate for the portion of the scene based on the depth estimates for the active slots.
FILED Thursday, August 29, 2019
APPL NO 16/556119
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 17/10 (20130101)
G01S 17/89 (20130101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 7/521 (20170101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11474344 Younts et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Information Warfare Center (NIWC)
Naval Information Warfare Center Pacific (NIWCPACIFIC)
APPLICANT(S) United States Government as represented by the Secretary of the Navy (San Diego, California)
ASSIGNEE(S) United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Robert Alexander Younts (Moncks Corner, South Carolina);  Tian-Bing Xu (Chesapeake, Virginia);  Laura Catherine Tolliver (Charleston, South Carolina)
ABSTRACT A programmable, deformable incident-energy shaper comprising: a base having top and bottom surfaces with a perforation there-between; a protrusion connected to, and extending outwardly from, a center of the top surface; a deformable layer firmly attached to the base's perimeter and to a tip of the protrusion such that a majority of the deformable layer is suspended in free space between the tip and the perimeter, wherein the deformable layer is configured to flex inwardly or outwardly, and wherein the perforation provides a fluid channel to ambient fluid; and an actuator, operatively coupled to the deformable layer and configured to cause the deformable layer to flex inwardly or outwardly upon command.
FILED Wednesday, November 04, 2020
APPL NO 17/089044
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 26/004 (20130101)
G02B 26/0825 (20130101) Original (OR) Class

Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for
G10K 15/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11475274 Bose et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Pradip Bose (Yorktown Heights, New York);  Alper Buyuktosunoglu (White Plains, New York);  Augusto J. Vega (Mount Vernon, New York)
ABSTRACT A computer-implemented method optimizes a neural network. One or more processors define layers in a neural network based on neuron locations relative to incoming initial inputs and original outgoing final outputs of the neural network, where a first defined layer is closer to the incoming initial inputs than a second defined layer, and where the second defined layer is closer to the original outgoing final outputs than the first defined layer. The processor(s) define parameter criticalities for parameter weights stored in a memory used by the neural network, and associate defined layers in the neural network with different memory banks based on the parameter criticalities for the parameter weights. The processor(s) store parameter weights used by neurons in the first defined layer in the first memory bank and parameter weights used by neurons in the second defined layer in the second memory bank.
FILED Friday, April 21, 2017
APPL NO 15/493263
ART UNIT 2129 — AI & Simulation/Modeling
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 3/082 (20130101)
G06N 3/105 (20130101)
G06N 3/0445 (20130101) Original (OR) Class
G06N 3/0472 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11476105 Newsome et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Research Laboratory (NRL)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Graham Asher Newsome (Riverdale, Maryland);  Kevin John Johnson (Odenton, Maryland);  Michael Paul Malito (Washington, District of Columbia)
ABSTRACT A method of transferring neutral gaseous material includes the steps of passing heated gas through flow tube in a central gas stream; and permeating a chemical dopant inward to the central gas stream through walls of the flow tube.
FILED Friday, March 19, 2021
APPL NO 17/207336
ART UNIT 2881 — Optics
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 49/0422 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11476340 Rajan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) Ohio State Innovation Foundation (Columbus, Ohio)
ASSIGNEE(S) Ohio State Innovation Foundation (Columbus, Ohio)
INVENTOR(S) Siddharth Rajan (Columbus, Ohio);  Zhanbo Xia (Columbus, Ohio);  Wyatt Moore (Columbus, Ohio)
ABSTRACT A device is provided that comprises a first layer deposited onto a second layer. The second layer comprises a lightly doped n-type or p-type semiconductor drift layer, and the first layer comprises a high-k material with a dielectric constant that is at least two times higher than the value of the second layer. A metal Schottky contact is formed on the first layer and a metal ohmic contact is formed on the second layer. Under reverse bias, the dielectric constant discontinuity leads to a very low electric field in the second layer, while the electron barrier created by the first layer stays almost flat. Under forward bias, electrons flow through the first layer, into the metal ohmic contact. For small values of conduction band offset or valence band offset between the first layer and the second layer, the device is expected to support efficient electron or hole transport.
FILED Tuesday, August 25, 2020
APPL NO 17/002253
ART UNIT 2818 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 29/24 (20130101)
H01L 29/408 (20130101) Original (OR) Class
H01L 29/872 (20130101)
H01L 31/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11476353 Jonker et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Berend T. Jonker (Waldorf, Maryland);  Connie H. Li (Alexandria, Virginia);  Kathleen M. McCreary (Washington, District of Columbia);  Olaf M. J. van 't Erve (Falls Church, Virginia)
ABSTRACT The invention relates to heterostructures including a layer of a two-dimensional material placed on a multiferroic layer. An ordered array of differing polarization domains in the multiferroic layer produces corresponding domains having differing properties in the two-dimensional material. When the multiferroic layer is ferroelectric, the ferroelectric polarization domains in the layer produce local electric fields that penetrate the two-dimensional material. The local electric fields modulate the charge carriers and carrier density on a nanometer length scale, resulting in the formation of lateral p-n or p-i-n junctions, and variations thereof appropriate for device functions. Methods for producing the heterostructures are provided. Devices incorporating the heterostructures are also provided.
FILED Tuesday, November 21, 2017
APPL NO 15/819959
ART UNIT 2812 — Semiconductors/Memory
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/4141 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/187 (20130101)
H01L 21/0242 (20130101)
H01L 21/0262 (20130101)
H01L 21/02381 (20130101)
H01L 21/02488 (20130101)
H01L 21/02568 (20130101)
H01L 21/02658 (20130101)
H01L 29/24 (20130101)
H01L 29/778 (20130101)
H01L 29/861 (20130101)
H01L 29/7391 (20130101)
H01L 29/66977 (20130101) Original (OR) Class
H01L 29/78696 (20130101)
H01L 33/002 (20130101)
H01L 33/04 (20130101)
H01L 33/26 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11476378 Abouraddy et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of the Navy (DON)
Office of Naval Research (ONR)
Multidisciplinary University Research Initiative (MURI)
APPLICANT(S) UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida)
ASSIGNEE(S) UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida)
INVENTOR(S) Ayman F. Abouraddy (Orlando, Florida);  Massimo Maximilian L. Villinger (Orlando, Florida);  Abbas Shiri (Orlando, Florida);  Soroush Shabahang (Orlando, Florida);  Ali K. Jahromi (Orlando, Florida);  Chris H. Villinger (Orlando, Florida)
ABSTRACT A visibly transparent planar structure using a CPA scheme to boost the absorption of a multi-layer thin-film configuration, requiring no surface patterning, to overcome the intrinsic absorption limitation of the absorbing material. This is achieved in a multi-layer absorbing Fabry-Perot (FP) cavity, namely a thin-film amorphous silicon solar cell. Omni-resonance is achieved across a bandwidth of 80 nm in the near-infrared (NIR), thus increasing the effective absorption of the material, without modifying the material itself, enhancing it beyond its intrinsic absorption over a considerable spectral range. The apparatus achieved an increased external quantum efficiency (EQE) of 90% of the photocurrent generated in the 80 nm NIR region from 660 to 740 nm as compared to a bare solar cell. over the spectral range of interest.
FILED Monday, May 04, 2020
APPL NO 16/865486
ART UNIT 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/075 (20130101) Original (OR) Class
H01L 31/202 (20130101)
H01L 31/0445 (20141201)
H01L 31/0547 (20141201)
H01L 31/03762 (20130101)
H01L 31/022475 (20130101)
H01L 31/022483 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11476555 Roper
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S) HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Christopher S. Roper (Oak Park, California)
ABSTRACT Disclosed are electrochemically tunable metamaterials which are capable of complete reversibility such that the metamaterial itself can physically disappear (out of the active region) and reappear later, in a controllable manner. Some variations provide an electrochemically tunable, solid-state metamaterial-based device comprising a plurality of metamaterial unit cells, wherein each of the metamaterial unit cells comprises: an ion conductor containing mobile metal ions; a first electrode in contact with the ion conductor, wherein the first electrode is contained in a metasurface negative space disposed on the ion conductor; a second electrode in contact with the ion conductor, wherein the second electrode is electrically isolated from the first electrode; and a metal-containing region containing one or more metals, wherein the metal-containing region is contained within a metasurface positive space disposed on the ion conductor.
FILED Saturday, July 27, 2019
APPL NO 16/524021
ART UNIT 2843 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/17 (20130101)
G02F 1/19 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 45/085 (20130101)
H01L 45/146 (20130101)
H01L 45/1266 (20130101)

Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 7/08 (20130101) Original (OR) Class
H01P 7/086 (20130101)
H01P 7/088 (20130101)

Antennas, i.e Radio Aerials
H01Q 1/364 (20130101)
H01Q 15/0086 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11476557 Sharma et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Information Warfare Center (NIWC)
Naval Information Warfare Center Pacific (NIWCPACIFIC)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (San Diego, California)
ASSIGNEE(S) United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Satish K. Sharma (Escondido, California);  Jia-Chi Samuel Chieh (San Diego, California)
ABSTRACT An antenna element transfers a radiofrequency signal and dissipates heat. The antenna element includes a periphery and first and second pairs of fins. The periphery has a length and a width with the length approximately equaling the width. The first and second pairs of fins extend in height from inside the periphery. The first pair of fins are separated by a shared gap for transferring a first polarization of the radiofrequency signal, and the second pair of fins are separated by the shared gap for transferring a second polarization of the radiofrequency signal that is orthogonal to the first polarization. An antenna array includes multiple instances of the antenna element for transferring the radiofrequency signal and for dissipating the heat.
FILED Friday, August 06, 2021
APPL NO 17/395673
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 1/02 (20130101) Original (OR) Class
H01Q 13/085 (20130101)
H01Q 21/064 (20130101)
H01Q 21/0081 (20130101)
H01Q 23/00 (20130101)
H01Q 25/001 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11476630 Campbell
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Robert Neil Campbell (Corrales, New Mexico)
ASSIGNEE(S)
INVENTOR(S) Robert Neil Campbell (Corrales, New Mexico)
ABSTRACT A thin film Brewster coupling device configured for low loss transmission of an imposed polarized parallel to plane of incidence 8.5 micron to 11.5 micron wavelength laser beam and simultaneous high reflectivity of a polarized perpendicular to plane of incidence 2 micron to 4 micron wavelength laser beam. The device comprising an optical media substrate and at least one dielectric stack optically coupled to the optical media substrate where the dielectric stack comprises a dielectric layer and an overlayer, the dielectric layer and the overlayer each comprising a thickness of nominally a quarter wavelength of the 2 micron to 4 micron wavelength laser beam, and oriented at near the Brewster Angle to the incident 8.5 micron to 11.5 micron wavelength laser beam. The substrate and dielectric mediums of necessary characteristics to result in low LIDT, high strength, chemical inertness and high thermal conductivity.
FILED Tuesday, June 01, 2021
APPL NO 17/336230
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/034 (20130101) Original (OR) Class
H01S 3/0943 (20130101)
H01S 3/1022 (20130101)
H01S 3/10061 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11476634 Dragic et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois);  Clemson University (Clemson, South Carolina)
ASSIGNEE(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois);  CLEMSON UNIVERSITY (Clemson, South Carolina)
INVENTOR(S) Peter Dragic (Champaign, Illinois);  John Ballato (Clemson, South Carolina);  Maxime Cavillon (Paris, France)
ABSTRACT A rare earth-doped optical fiber comprises a fluorosilicate core surrounded by a silica cladding, where the fluorosilicate core comprises an alkaline-earth fluoro-alumino-silicate glass, such as a strontium fluoro-alumino-silicate glass. The rare earth-doped optical fiber may be useful as a high-power fiber laser and/or fiber amplifier. A method of making a rare earth-doped optical fiber comprises: inserting a powder mixture comprising YbF3, SrF2, and Al2O3 into a silica tube; after inserting the powder mixture, heating the silica tube to a temperature of at least about 2000° C., some or all of the powder mixture undergoing melting; drawing the silica tube to obtain a reduced-diameter fiber; and cooling the reduced-diameter fiber. Thus, a rare earth-doped optical fiber comprising a fluorosilicate core surrounded by a silica cladding is formed.
FILED Tuesday, May 07, 2019
APPL NO 16/404955
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/173 (20130101)
H01S 3/176 (20130101)
H01S 3/1698 (20130101) Original (OR) Class
H01S 3/06733 (20130101)
H01S 3/06754 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11476837 Choi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) U.S. Army Combat Capabilities Development Command, Army Research Laboratory (Adelphi, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Jihun Choi (Silver Spring, Maryland);  Fikadu T. Dagefu (Silver Spring, Maryland);  Brian M. Sadler (Laurel, Maryland);  Kamal Sarabandi (Ann Arbor, Michigan)
ABSTRACT An active matching network for impedance matching to a miniature antenna, comprising a cross-coupled transistor pair, where each transistor has an emitter, base and collector, the emitter of a first transistor forms an input terminal, the emitter of a second transistor forms on output terminal, the collector of the first transistor coupled to the base of the second transistor, the collector of the second transistor coupled to the base of the first transistor, and a matching circuit coupled between the collectors of the first and second transistors. The matching network is configured to match an impendence near resonance of the high Q miniature antenna to an input impedance using a complex negative impedance comprising resistance, inductance and capacitance.
FILED Monday, June 08, 2020
APPL NO 16/895490
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 9/04 (20130101)

Impedance Networks, e.g Resonant Circuits; Resonators
H03H 11/28 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11477122 Flajslik et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) Intel Corporation (Santa Clara, California)
ASSIGNEE(S) Intel Corporation (Santa Clara, California)
INVENTOR(S) Mario Flajslik (Hopkinton, Massachusetts);  Eric R. Borch (Fort Collins, Colorado);  Timo Schneider (Hudson, Massachusetts);  Michael A. Parker (Santa Clara, California)
ABSTRACT Technologies for improving throughput in a network include a node switch. The node switch is to obtain expected performance data indicative of an expected data transfer performance of the node switch. The node switch is also to obtain measured performance data indicative of a measured data transfer performance of the node switch, compare the measured performance data to the expected performance data to determine whether the measured data transfer performance satisfies the expected data transfer performance, determine, as a function of whether the measured data transfer performance satisfies the expected data transfer performance, whether to force a unit of data through a non-minimal path to a destination, and send, in response to a determination to force the unit of data to be sent through a non-minimal path, the unit of data to an output port of the node switch associated with the non-minimal path. Other embodiments are also described.
FILED Wednesday, September 27, 2017
APPL NO 15/716831
ART UNIT 2476 — Multiplex and VoIP
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 41/0893 (20130101)
H04L 41/0896 (20130101)
H04L 43/0882 (20130101)
H04L 43/0888 (20130101)
H04L 43/0894 (20130101)
H04L 45/123 (20130101)
H04L 47/22 (20130101) Original (OR) Class
H04L 47/6255 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11477652 Bilinski et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (San Diego, California)
ASSIGNEE(S) United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Mark Bilinski (Vista, California);  Gerald Thomas Burnette (San Diego, California);  Fred William Greene (San Diego, California);  Garrison Buckminster Price (San Diego, California)
ABSTRACT The system and methods described herein aids in the defense of unmanned vehicles, such as aerial vehicles, from wifi cyber attacks. Such attacks usually do not last long and in the case of many point-to-point command and control systems, the attacks originate from close proximity to the unmanned vehicle. The system and methods described herein allow a team to rapidly identify and physically respond to an adversary trying to take control of the unmanned vehicle. Another aspect of the embodiment taught herein is to allow for the location of a wifi signal in a hands-free manner by able to visualize the source of the signal using an augmented reality display coupled to an antenna array.
FILED Monday, November 25, 2019
APPL NO 16/694737
ART UNIT 2677 — Facsimile; Printer; Color; halftone; Scanner; Computer Graphic Processing; 3-D Animation; Display Color; Attributes; Object Processing; Hardware and Memory
CURRENT CPC
Aeroplanes; Helicopters
B64C 39/024 (20130101)
B64C 2201/027 (20130101)

Image Data Processing or Generation, in General
G06T 11/00 (20130101)
G06T 2200/24 (20130101)

Wireless Communication Networks
H04W 12/122 (20210101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11477888 Nino
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Quest Integrated, LLC (Kent, Washington)
ASSIGNEE(S) Quest Integrated, LLC (Renton, Washington)
INVENTOR(S) Giovanni Nino (Issaquah, Washington)
ABSTRACT Systems and methods for printed multifunctional skins are disclosed herein. In one embodiment, an aerodynamic apparatus includes an aerodynamic structure having a first surface exposed to an outside environment, and a second surface exposed to an inside environment. A printed sensor is carried by the first surface of the aerodynamic structure, electronic components are carried by the second surface of the aerodynamic structure, and at least one printed conductive trace is carried by the first surface and the second surface. The printed conductive trace electrically connects the printed sensor with the electronics.
FILED Monday, October 08, 2018
APPL NO 16/154509
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Aeroplanes; Helicopters
B64C 1/12 (20130101)
B64C 3/26 (20130101)
B64C 39/024 (20130101)

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 45/00 (20130101)
B64D 2045/0085 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 1/16 (20130101) Original (OR) Class
H05K 2201/10151 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 439/91 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 11471785 Abbasi et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Oregon State University (Corvallis, Oregon)
ASSIGNEE(S) Oregon State University (Corvallis, Oregon)
INVENTOR(S) Bahman Abbasi (Bend, Oregon);  Xiang Zhang (Bend, Oregon);  Hannah O'Hern (Corvallis, Oregon);  Elnaz Nikooei (Corvallis, Oregon)
ABSTRACT This disclosure concerns a system for purifying contaminated water and a method for using the system. More specifically, the invention concerns removing contaminants, such as those introduced by fracking, from a contaminated water.
FILED Tuesday, August 04, 2020
APPL NO 16/985043
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 1/0023 (20130101)
B01D 1/305 (20130101) Original (OR) Class
B01D 3/346 (20130101)
B01D 5/006 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/10 (20130101)
C02F 2101/12 (20130101)
C02F 2101/16 (20130101)
C02F 2101/34 (20130101)
C02F 2101/101 (20130101)
C02F 2101/108 (20130101)
C02F 2101/301 (20130101)
C02F 2101/322 (20130101)
C02F 2103/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471825 Li et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S) GAS TECHNOLOGY INSTITUTE (Des Plaines, Illinois)
ASSIGNEE(S) GAS TECHNOLOGY INSTITUTE (Des Plaines, Illinois)
INVENTOR(S) Shiguang Li (Mount Prospect, Illinois);  Travis Pyrzynski (Elgin, Illinois);  Howard Meyer (Hoffman Estates, Illinois);  Naomi Klinghoffer (Chicago, Illinois);  Timothy Tamale (Schaumburg, Illinois)
ABSTRACT Processes and systems for the capture of CO2 from a CO2-containing gas stream are provided. The CO2-containing gas stream is passed to a membrane contactor absorber wherein the CO2-containing gas contacts or passes a first side of a membrane element while a CO2 selective solvent with a viscosity between 0.2 and 7 cP contacts, passes or flows on second side of the membrane, opposed to the first side. The CO2 permeates through the hollow fiber membrane pores and is chemically absorbed into the solvent.
FILED Thursday, March 14, 2019
APPL NO 16/353079
ART UNIT 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 53/96 (20130101)
B01D 53/228 (20130101) Original (OR) Class
B01D 53/229 (20130101)
B01D 69/08 (20130101)
B01D 2252/204 (20130101)
B01D 2252/504 (20130101)
B01D 2252/2025 (20130101)
B01D 2257/504 (20130101)
B01D 2325/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471838 Dervishi et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Triad National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S) Triad National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Enkeleda Dervishi (Los Alamos, New Mexico);  Justin R. Marquez (Los Alamos, New Mexico);  Quinn McCulloch (Los Alamos, New Mexico);  Stephen L. Yarbro (Los Alamos, New Mexico);  Eric L. Auchter (Los Alamos, New Mexico)
ABSTRACT A microfluidic assembly can include a first microchannel substrate defining one or more first microchannels, a second microchannel substrate defining one or more second microchannels. The assembly can further include a membrane positioned between the first and second microchannel substrates and comprising a first polymeric layer, a second polymeric layer, and one or more graphene layers disposed between the first and second polymeric layers. At least a portion of the first microchannels can overlap at least a portion of the second microchannels such that, when a first fluid is present in the first microchannels and a second fluid is present in the second microchannels, the first fluid and the second fluid contact opposite sides of the membrane.
FILED Monday, August 05, 2019
APPL NO 16/531600
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 63/00 (20130101)
B01D 69/12 (20130101) Original (OR) Class
B01D 71/021 (20130101)
B01D 2313/20 (20130101)
B01D 2325/028 (20130101)

Microstructural Devices or Systems, e.g Micromechanical Devices
B81B 3/0089 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471865 Tait et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana)
ASSIGNEE(S) THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana)
INVENTOR(S) Steven L. Tait (Bloomington, Indiana);  Linxiao Chen (Issaquah, Washington)
ABSTRACT The invention describes single-site metal catalysts such as Pt single-site centers with a 3,6-di-2-pyridyl-1,2,4,5-tetrazine (DPTZ) ligand on support such as a powdered MgO, Al2O3, CeO2 or mixtures thereof.
FILED Tuesday, December 17, 2019
APPL NO 16/717069
ART UNIT 1738 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 6/001 (20130101)
B01J 23/10 (20130101)
B01J 31/12 (20130101) Original (OR) Class
B01J 37/04 (20130101)
B01J 37/06 (20130101)
B01J 37/0027 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471916 Kumar et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Sortera Alloys, Inc. (Fort Worth, Texas)
ASSIGNEE(S) SORTERA ALLOYS, INC. (Fort Wayne, Indiana)
INVENTOR(S) Nalin Kumar (Fort Worth, Texas);  Manuel Gerardo Garcia, Jr. (Lexington, Kentucky);  Isha Kamleshbhai Maun (Arlington, Texas)
ABSTRACT A material sorting system sorts materials utilizing a vision system that implements a machine learning system in order to identify or classify each of the materials, which are then sorted into separate groups based on such an identification or classification determining that the materials are composed of either wrought aluminum, extruded aluminum, or cast aluminum.
FILED Sunday, July 26, 2020
APPL NO 16/939011
ART UNIT 3653 — Organic Chemistry
CURRENT CPC
Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking
B07C 5/04 (20130101)
B07C 5/34 (20130101)
B07C 5/342 (20130101)
B07C 5/3422 (20130101) Original (OR) Class
B07C 2501/0054 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471940 Pu et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
National Aeronautics and Space Administration (NASA)
Merced Nanomaterials Center for Energy and Sensing (MACES)
NASA Shared Services Center (NSSC)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Ying-Chih Pu (Santa Cruz, California);  Frank Song (Santa Cruz, California);  Weichun Zhang (Santa Cruz, California);  Sarah Lindley (Santa Cruz, California);  Staci Adams (Santa Cruz, California);  Jin Zhang (Santa Cruz, California)
ABSTRACT Provided are methods of producing cobalt nanoparticles (Co NPs). The methods include combining a cobalt salt, a capping agent, and a reducing agent, under Co NP synthesis conditions including a temperature selected to produce cobalt nanoparticles of a pre-selected diameter, where the temperature and pre-selected diameter are inversely related. In certain aspects, the methods further include producing hollow gold nano spheres (HGNs) using the cobalt nanoparticles as scaffolds. Also provided are cobalt nanoparticles and hollow gold nano spheres (HGNs) produced according to the present methods. Kits that find use in practicing the methods of the present disclosure are also provided.
FILED Friday, December 01, 2017
APPL NO 16/465708
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/062 (20130101)

Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/054 (20220101) Original (OR) Class
B22F 1/0549 (20220101)
B22F 9/24 (20130101)
B22F 2301/15 (20130101)
B22F 2301/255 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471946 Lienert et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Triad National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S) Triad National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Thomas J. Lienert (Los Alamos, New Mexico);  Stuart Andrew Maloy (Los Alamos, New Mexico);  Benjamin P. Eftink (Los Alamos, New Mexico);  Daniel Vega (Los Alamos, New Mexico)
ABSTRACT Techniques for using additive manufacturing (AM) to fabricate creep resistant ferritic/martensitic steel with improved high temperature strength are described. AM processing may be performed on Grade 91 steel powder. Beam powers from about 221 W to about 270 W may be used. Traverse rates from about 675 mm/s to about 825 mm/s may be used. Heat inputs ranging from about 55.7 J/mm3 to about 83.2 J/mm3 may be produced. Creep resistant ferritic/martensitic steel, produced according to the present disclosure, has improved strain yield strength and ductility as compared to wrought steel.
FILED Friday, September 06, 2019
APPL NO 16/563278
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 10/10 (20210101)
B22F 12/00 (20210101) Original (OR) Class
B22F 2301/35 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
B33Y 70/00 (20141201)
B33Y 80/00 (20141201)

Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering
C21D 2211/008 (20130101)

Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys
C22F 1/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11472519 Sirnivas et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) Senu Sirnivas (Broomfield, Colorado);  Rick Riccardo Damiani (Arvada, Colorado);  Fabian Ferdinand Wendt (Boulder, Colorado)
ABSTRACT Disclosed herein are aquatic substructures capable of supporting a weight such as a wind tower and turbine. The aquatic substructures may include a central column and at least one buoyancy container connected by means of a system of cables and beams as described herein.
FILED Wednesday, January 30, 2019
APPL NO 16/966251
ART UNIT 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Ships or Other Waterborne Vessels; Equipment for Shipping
B63B 1/14 (20130101)
B63B 1/107 (20130101)
B63B 21/50 (20130101)
B63B 35/44 (20130101) Original (OR) Class
B63B 2001/145 (20130101)
B63B 2035/446 (20130101)

Machines or Engines for Liquids
F03B 13/182 (20130101)
F03B 13/1815 (20130101)

Wind Motors
F03D 13/25 (20160501)

Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G
F05B 2240/93 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/727 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11472746 Agarwal et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
APPLICANT(S) Arvind Agarwal (Miami, Florida);  Ambreen Nisar (Miami, Florida);  Tony Thomas (Miami, Florida);  Kazue Orikasa (Miami, Florida);  Benjamin Peter Boesl (Miami, Florida)
ASSIGNEE(S) THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S) Arvind Agarwal (Miami, Florida);  Ambreen Nisar (Miami, Florida);  Tony Thomas (Miami, Florida);  Kazue Orikasa (Miami, Florida);  Benjamin Peter Boesl (Miami, Florida)
ABSTRACT Ultra-high temperature carbide (UHTC) foams and methods of fabricating and using the same are provided. The UHTC foams are produced in a three-step process, including UHTC slurry preparation, freeze-drying, and spark plasma sintering (SPS). The fabrication methods allow for the production of any kind of single- or multi-component UHTC foam, while also providing flexibility in the shape and size of the UHTC foams to produce near-net-shape components.
FILED Monday, December 06, 2021
APPL NO 17/457778
ART UNIT 1759 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster
B28B 1/14 (20130101)

Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/5607 (20130101)
C04B 35/5622 (20130101) Original (OR) Class
C04B 35/6263 (20130101)
C04B 35/6264 (20130101)
C04B 35/62655 (20130101)
C04B 35/63424 (20130101)
C04B 38/0038 (20130101)
C04B 38/0054 (20130101)
C04B 2235/606 (20130101)
C04B 2235/666 (20130101)
C04B 2235/3839 (20130101)
C04B 2235/6021 (20130101)
C04B 2235/6567 (20130101)
C04B 2235/9607 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11472915 Swager et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Timothy M. Swager (Newton, Massachusetts);  Yuan He (Cambridge, Massachusetts);  Zachary Smith (Belmont, Massachusetts);  Sharon Lin (Somerville, Massachusetts);  Francesco Maria Benedetti (Urbania, Italy)
ABSTRACT Porous compositions such as flexible polymers with side chain porosity are generally provided. In some embodiments, the composition comprises a flexible polymer backbone and a plurality of rigid side chains. In some embodiments, the rigid side chains form pores. In some embodiments, the rigid side chains may comprise two or more [2.2.2] bicyclic cores (e.g., formed by a ring opening metathesis polymerization. The compounds and methods described herein may be useful in various applications including, for example, gas separation.
FILED Friday, June 07, 2019
APPL NO 16/435397
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Separation
B01D 53/228 (20130101)
B01D 71/28 (20130101)
B01D 71/44 (20130101)
B01D 2325/02 (20130101)
B01D 2325/20 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 61/08 (20130101) Original (OR) Class
C08G 2261/3324 (20130101)
C08G 2261/3325 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11472960 Bova et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee);  University of Tennessee Research Foundation (Knoxville, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee);  University of Tennessee Research Foundation (Knoxville, Tennessee)
INVENTOR(S) Anthony S. Bova (McLean, Virginia);  Amit K. Naskar (Knoxville, Tennessee)
ABSTRACT A solid multiphase polymer blend material comprising: (i) a polyphenolic substance having a molecular weight of at least 500 g/mol; and (ii) a polyester having a molecular weight of at least 500 g/mol; wherein at least a portion of the polyphenolic substance is covalently bonded directly or through a linking moiety to the polyester. Methods for producing the blend material are also described, e.g., homogeneously melt blending a mixture comprising components (i) and (ii) under conditions resulting in covalent attachment of at least a portion of the polyphenolic substance directly or through a linking moiety to the polyester. Methods for producing objects made of the blend material by melt extrusion are also described.
FILED Friday, January 29, 2021
APPL NO 17/162658
ART UNIT 1759 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Compositions of Macromolecular Compounds
C08L 67/03 (20130101)
C08L 67/04 (20130101) Original (OR) Class
C08L 71/02 (20130101)
C08L 97/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11473086 Xie et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Meng Xie (Oak Ridge, Tennessee);  Jin-Gui Chen (Oak Ridge, Tennessee);  Lee E. Gunter (Oak Ridge, Tennessee);  Sara S. Jawdy (Oak Ridge, Tennessee);  Wellington Muchero (Oak Ridge, Tennessee);  Gerald Tuskan (Oak Ridge, Tennessee);  Jin Zhang (Oak Ridge, Tennessee)
ABSTRACT The present disclosure provides genetically modified plants, plant cells and plant tissues that show reduced lignin content as compared to a control plant which was not genetically modified. In addition, the disclosure provides methods of regulating lignin content in a plant. The disclosure also provides methods of producing bioproducts using the genetically modified plants of the instant disclosure.
FILED Wednesday, June 19, 2019
APPL NO 16/445888
ART UNIT 1663 — Plants
CURRENT CPC
New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques
A01H 6/4636 (20180501)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 15/8213 (20130101)
C12N 15/8255 (20130101)
C12N 2310/11 (20130101)
C12N 2310/12 (20130101)
C12N 2310/141 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11473141 Meagher et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Robert Meagher (Mountain House, California);  Chung-Yan Koh (Arlington, Virginia);  Yooli Kim Light (Pleasanton, California);  Cameron Scott Ball (Los Altos, California)
ABSTRACT The present invention relates to probes and primers beneficial for conducting amplification assays, such as those including loop-mediated isothermal amplification reactions. Also described herein are methods for detecting targets using such probes and/or primers.
FILED Tuesday, June 16, 2020
APPL NO 16/903075
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6818 (20130101)
C12Q 1/6876 (20130101) Original (OR) Class
C12Q 2600/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11473564 He et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Lijun He (Schenectady, New York);  Liwei Hao (Niskayuna, New York);  John Mihok (Schenectady, New York)
ABSTRACT A system and method for monitoring a pitch system of a wind turbine includes monitoring, via one or more first sensors, at least one electrical condition of the pitch system. The method also includes monitoring, via one or more second sensors, at least one mechanical condition of the pitch system. Further, the method includes receiving, via a controller communicatively coupled to the one or more first and second sensors, sensor signals representing the at least one electrical condition and the at least one mechanical condition of the pitch system. Thus, the method includes determining, via the controller, a bearing condition of a pitch bearing of the pitch system based on the at least one electrical condition and the at least one mechanical condition of the pitch system.
FILED Thursday, January 18, 2018
APPL NO 15/874124
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Wind Motors
F03D 7/0224 (20130101)
F03D 17/00 (20160501) Original (OR) Class
F03D 80/50 (20160501)
F03D 80/70 (20160501)

Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G
F05B 2260/79 (20130101)
F05B 2260/80 (20130101)

Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for
G01M 13/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11473689 Gherini et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Michael James Gherini (San Ramon, California);  Ryan K. Gehmlich (Mountain House, California);  Dorian K. Balch (Oakland, California);  Michael Christopher Maguire (Napa, California)
ABSTRACT A passive tube closure valve comprising an elongated body extending along a first axis made of a shape memory alloy with a threshold contraction along the first axis at a threshold temperature. The closure valve further comprises a passageway extending along a second axis different from the first axis shaped to surround a conduit line extending along the second axis. The closure valve further includes a first modifying structure on a first portion of the passageway and a second modifying structure on a second portion of the passageway opposite the first modifying structure. Contraction of the elongated body can cause the first modifying structure and the second modifying structure to move towards each other; where movement of at least one of the first modifying structure or the second modifying structures can be configured to modify the conduit line.
FILED Tuesday, October 13, 2020
APPL NO 17/069257
ART UNIT 3753 — Fluid Handling and Dispensing
CURRENT CPC
Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for
F03G 7/065 (20130101)

Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating
F16K 31/002 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11474044 Reed et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) ADVANCED POLYMER MONITORING TECHNOLOGIES, INC. (New Orleans, Louisiana);  THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (New Orleans, Louisiana)
ASSIGNEE(S) ADVANCED POLYMER MONITORING TECHNOLOGIES, INC. (New Orleans, Louisiana);  THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (New Orleans, Louisiana)
INVENTOR(S) Wayne Frederick Reed (New Orleans, Louisiana);  Rick D. Montgomery (New Orleans, Louisiana);  Michael Felix Drenski (New Orleans, Louisiana);  Aide Wu (New Orleans, Louisiana)
ABSTRACT Devices and methods for determining the cumulative distribution of a polymer property in a reactor without physical separation of reaction subcomponents. The device includes a means of measuring an instantaneous property of the polymers being produced in a reaction vessel a plurality of times during a polymerization reaction as well as a means of determining the corresponding change in polymer concentration in the reaction vessel between measurements of the instantaneous polymer property The device also includes a means of computing a statistical distribution appropriate to the polymer characteristic and applying the statistical distribution to a recently measured instantaneous value of the polymer property so as to have an instantaneous distribution of the polymer property and a means of adding together the instantaneous distributions of the polymer property in order to obtain the cumulative distribution of the polymer property in the reactor.
FILED Friday, April 21, 2017
APPL NO 16/094542
ART UNIT 2863 — Printing/Measuring and Testing
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/0006 (20130101)
B01J 2219/002 (20130101)
B01J 2219/00186 (20130101)
B01J 2219/00218 (20130101)
B01J 2219/00231 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 20/56 (20130101)
C08F 2400/02 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/75 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11474073 Sinha et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Triad National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S) TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico)
INVENTOR(S) Dipen N. Sinha (Los Alamos, New Mexico);  Cristian Pantea (Los Alamos, New Mexico);  Blake T. Sturtevant (Lewiston, Maine);  Anirban Chaudhuri (Cary, North Carolina)
ABSTRACT Methods for noninvasive determination of acoustical properties of flowing in pipes having a large ratio (>10) of pipe diameter to wall thickness, and in highly attenuating fluids are described. When vibrations are excited on the outer surface of the wall of a pipe, the resulting vibrations propagate directly through the wall in a normal direction and through the pipe wall as guided waves, appearing on the opposite side of the pipe. This dual path propagation through pipes, where guided waves take the circumferential path in the wall of the pipe and may interfere with the time of-flight measurement obtained from the direct path through the fluid, is at least in part resolved by subtracting the signal from the guided wave from the combined signal, thereby permitting improved observation of the direct path propagation through the fluid.
FILED Thursday, July 20, 2017
APPL NO 16/318862
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves
G01H 11/06 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 29/024 (20130101) Original (OR) Class
G01N 29/223 (20130101)
G01N 2291/043 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11474106 Henderson et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) ACCELERATED MEDICAL DIAGNOSTICS, INC. (Berkeley, California);  LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California);  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
INVENTOR(S) Paul Henderson (Berkeley, California);  George D. Cimino (Lafayette, California);  Chong-Xian Pan (Davis, California);  Ralph William de Vere White (Sacramento, California);  Maike Zimmermann (Davis, California);  Kenneth W. Turteltaub (Livermore, California)
ABSTRACT The invention relates to methods, systems and kits for determining therapeutic effectiveness or toxicity of cancer-treating compounds that incorporate into or bind to DNA. In particular, the invention is directed to methods, systems and kits for predicting a patient's treatment outcome after administration of a microdose of therapeutic composition to the patient. The methods provides physicians with a diagnostic tool to segregate cancer patients into differential populations that have a higher or lower chance of responding to a particular therapeutic treatment.
FILED Thursday, July 07, 2016
APPL NO 15/742454
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/28 (20130101)
A61K 31/395 (20130101)
A61K 31/555 (20130101)
A61K 31/555 (20130101)
A61K 31/7068 (20130101)
A61K 31/7068 (20130101)
A61K 33/24 (20130101)
A61K 33/243 (20190101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/60 (20130101)
G01N 33/96 (20130101)
G01N 33/5308 (20130101)
G01N 33/6848 (20130101)
G01N 33/57484 (20130101) Original (OR) Class
G01N 2800/52 (20130101)
G01N 2800/56 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11474283 te Velthuis et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S) Suzanne Gabriëlle Everdine te Velthuis (Naperville, Illinois);  Michael Claus Siegfried Vogel (Westmont, Illinois);  Axel Friedrich Hoffmann (Champaign, Illinois)
ABSTRACT Sub-diffraction limited magneto-optical microscopy, such as Kerr or Faraday effect microscopy, provide many advantages to fields of science and technology for measuring, or imaging, the magnetization structures and magnetization domains of materials. Disclosed is a method and system for performing sub-diffraction limited magneto-optic microscopy. The method includes positioning a microlens or microlens layer relative to a surface of a sample to image the surface of the sample, forming a photonic nanojet to probe the surface of the sample, and receiving light reflected by the surface of the sample or transmitted through the sample at an imaging sensor. The methods and associated systems and devices enable sub-diffraction limited imaging of magnetic domains at resolutions 2 to 8 times the classical diffraction limit.
FILED Tuesday, June 30, 2020
APPL NO 16/916895
ART UNIT 2886 — Optics
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 20/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/17 (20130101)
G01N 21/21 (20130101)
G01N 2021/218 (20130101)
G01N 2021/8848 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/032 (20130101)
G01R 33/0322 (20130101)
G01R 33/0325 (20130101)

Optical Elements, Systems, or Apparatus
G02B 3/0037 (20130101) Original (OR) Class
G02B 21/0016 (20130101)
G02B 27/56 (20130101)
G02B 27/58 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11474897 Mills et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Nvidia Corporation (Santa Clara, California)
ASSIGNEE(S) Nvidia Corporation (Santa Clara, California)
INVENTOR(S) Peter Mills (Santa Clara, California);  Michael Sullivan (Santa Clara, California);  Nirmal Saxena (Santa Clara, California);  John Brooks (Santa Clara, California)
ABSTRACT Often there are errors when reading data from computer memory. To detect and correct these errors, there are multiple types of error correction codes. Disclosed is an error correction architecture that creates a codeword having a data portion and an error correction code portion. Swizzling rearranges the order of bits and distributes the bits among different codewords. Because the data is redistributed, a potential memory error of up to N contiguous bits, where N for example equals 2 times the number of codewords swizzled together, only affects up to, at most, two bits per swizzled codeword. This keeps the error within the error detecting capabilities of the error correction architecture. Furthermore, this can allow improved error correction and detection without requiring a change to error correcting code generators and checkers.
FILED Friday, March 15, 2019
APPL NO 16/355309
ART UNIT 2112 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electric Digital Data Processing
G06F 3/0619 (20130101)
G06F 3/0659 (20130101)
G06F 3/0673 (20130101)
G06F 11/10 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11475124 Abbaszadeh et al.
FUNDED BY
Department of Energy (DOE)
Office of Electricity (DOE-OE)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Masoud Abbaszadeh (Clifton Park, New York);  Lalit Keshav Mestha (North Colonie, New York)
ABSTRACT The example embodiments are directed to a system and method for forecasting anomalies in feature detection. In one example, the method includes storing feature behavior information of at least one monitoring node of an asset, including a normalcy boundary identifying normal feature behavior and abnormal feature behavior for the at least one monitoring node in feature space, receiving input signals from the at least one monitoring node of the asset and transforming the input signals into feature values in the feature space, wherein the feature values are located within the normalcy boundary, forecasting that a future feature value corresponding to a future input signal from the at least one monitoring node is going to be positioned outside the normalcy boundary based on the feature values within the normalcy boundary, and outputting information concerning the forecasted future feature value being outside the normalcy boundary for display.
FILED Monday, May 15, 2017
APPL NO 15/594779
ART UNIT 2495 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/552 (20130101) Original (OR) Class
G06F 21/577 (20130101)

Computer Systems Based on Specific Computational Models
G06N 5/04 (20130101)
G06N 20/00 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11476082 Bloom et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Integrated Dynamic Electron Solutions, Inc. (Pleasanton, California)
ASSIGNEE(S) INTEGRATED DYNAMIC ELECTRON SOLUTIONS, INC. (Pleasanton, California)
INVENTOR(S) Ruth Shewmon Bloom (Oakland, California);  Bryan Walter Reed (San Leandro, California);  Daniel Joseph Masiel (Alamo, California);  Sang Tae Park (Danville, California)
ABSTRACT A device may include an electron source, a detector, and a deflector. The electron source may be directed toward a sample area. The detector may receive an electron signal or an electron-induced signal. A deflector may be positioned between the electron source and the sample. The deflector may modulate an intensity of the electron source directed to the sample area according to an electron dose waveform having a continuously variable temporal profile.
FILED Monday, March 07, 2022
APPL NO 17/688339
ART UNIT 2881 — Optics
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 37/28 (20130101)
H01J 37/147 (20130101)
H01J 37/243 (20130101) Original (OR) Class
H01J 37/292 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11476376 Vawter et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Gregory A. Vawter (Corrales, New Mexico);  Erik J. Skogen (Tijeras, New Mexico);  Charles Alford (Albuquerque, New Mexico);  Junoh Choi (Albuquerque, New Mexico)
ABSTRACT A hybrid-integrated series/parallel-connected photovoltaic diode array employs 10s-to-100s of single-wavelength III-V compound semiconductor photodiodes in an array bonded onto a transparent optical plate through which the array is illuminated by monochromatic light. The power-by-light system receiver enables high-voltage, up to 1000s of volts, optical transmission of power to remote electrical systems in harsh environments.
FILED Wednesday, March 27, 2019
APPL NO 16/366942
ART UNIT 1759 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/054 (20141201)
H01L 31/075 (20130101)
H01L 31/0443 (20141201)
H01L 31/0504 (20130101) Original (OR) Class
H01L 31/03044 (20130101)
H01L 31/03046 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 50/30 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11476470 Steinbach et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) 3M INNOVATIVE PROPERTIES COMPANY (St. Paul, Minnesota)
ASSIGNEE(S) 3M Innovative Properties Company (St. Paul, Minnesota)
INVENTOR(S) Andrew J. L. Steinbach (Shoreview, Minnesota);  Andrew T. Haug (Woodbury, Minnesota);  Krzysztof A. Lewinski (Mahtomedi, Minnesota);  Amy E. Hester (Hudson, Wisconsin);  Grant M. Thoma (Woodbury, Minnesota);  Cedric Bedoya (Woodbury, Minnesota);  James A. Phipps (River Falls, Wisconsin);  David J. Rowe (Roseville, Minnesota);  Cemal S. Duru (Woodbury, Minnesota)
ABSTRACT Catalyst comprising a first layer having an outer layer with a layer comprising Pt directly thereon, wherein the first layer has an average thickness in a range from 0.04 to 30 nanometers, and wherein the layer. Catalysts described herein are useful, for example, in fuel cell membrane electrode assemblies.
FILED Thursday, April 11, 2019
APPL NO 15/733736
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/94 (20130101)
H01M 4/925 (20130101)
H01M 4/8657 (20130101) Original (OR) Class
H01M 4/8871 (20130101)
H01M 4/9058 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11476480 Dobek et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S) FuelCell Energy, Inc. (Danbury, Connecticut)
ASSIGNEE(S) FuelCell Energy, Inc. (Danbury, Connecticut)
INVENTOR(S) Frank Dobek (Colchester, Connecticut);  Stephen Jolly (Southington, Connecticut);  Keith Davis (Southbury, Connecticut)
ABSTRACT A steam vaporizer assembly includes an internal steam generator having a vessel configured to hold water, a vaporizer unit having a heating element configured to heat the water to generate saturated steam; and a controller configured to: cause the heating element to heat the water to a stand-by temperature; and while maintaining a water level of the water in the vessel between two control points: maintain the water in the vessel at the stand-by temperature until steam generation is required, and when steam generation is required, heating the water in the vessel from the stand-by temperature to a temperature at or above a vaporization temperature of the water using a heating element, to generate the steam.
FILED Wednesday, September 20, 2017
APPL NO 15/710591
ART UNIT 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Methods of Steam Generation; Steam Boilers
F22B 1/284 (20130101)
F22B 33/18 (20130101)
F22B 35/00 (20130101)

Preheating, or Accumulating Preheated, Feed-water for Steam Generation; Feed-water Supply for Steam Generation; Controlling Water Level for Steam Generation; Auxiliary Devices for Promoting Water Circulation Within Steam Boilers
F22D 5/26 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 8/04 (20130101)
H01M 8/0618 (20130101)
H01M 8/0637 (20130101)
H01M 8/04037 (20130101)
H01M 8/04373 (20130101) Original (OR) Class
H01M 2008/1293 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11476485 Park et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico)
ASSIGNEE(S) TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico)
INVENTOR(S) Eun Joo Park (Los Alamos, New Mexico);  Yu Seung Kim (Los Alamos, New Mexico);  Sandipkumar Maurya (Los Alamos, New Mexico)
ABSTRACT A polyaromatic electrolyte for a fuel cell electrode includes a structure represented by Formula 1, wherein in Formula 1, Ar is a neutral unit represented by one of Formula 2A and Formula 2B:
The fuel cell electrode may include a catalyst suspended in the polyaromatic electrolyte.
FILED Friday, May 31, 2019
APPL NO 16/428803
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 61/10 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/925 (20130101)
H01M 8/1023 (20130101) Original (OR) Class
H01M 2004/8684 (20130101)
H01M 2008/1095 (20130101)
H01M 2300/0082 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11476778 Li et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Basic Energy Sciences (BES)
National Science Foundation (NSF)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Anyin Li (Atlanta, Georgia);  Facundo Martin Fernandez (Atlanta, Georgia);  Yunlong Zi (Atlanta, Georgia)
ABSTRACT An ion pulse generator (100) includes a triboelectric generator (110), an ion emitter (132) and a conductive surface (134). The triboelectric generator (110) includes a first electrode (114), a spaced apart second electrode (120) and a first triboelectric layer (116). The triboelectric generator (110) generates a predetermined amount of charge as a result of relative movement of the first triboelectric layer (116). The ion emitter (132) is electrically coupled to the first electrode (114). The conductive surface (134) is electrically coupled to the second electrode (120) and is spaced apart from the ion emitter (132) at a predetermined distance. Generation of the predetermined amount of charge causes formation of ions between the ion emitter (132) and the conductive surface (134).
FILED Tuesday, September 12, 2017
APPL NO 16/645269
ART UNIT 2881 — Optics
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 49/10 (20130101)
H01J 49/26 (20130101)
H01J 49/165 (20130101)
H01J 49/167 (20130101)
H01J 49/168 (20130101)

Electric Machines Not Otherwise Provided for
H02N 1/004 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11477213 Pan et al.
FUNDED BY
Department of Energy (DOE)
Office of Electricity (DOE-OE)
APPLICANT(S) ABB Schweiz AG (Baden, Switzerland)
ASSIGNEE(S) ABB SCHWEIZ AG (Baden, Switzerland)
INVENTOR(S) Jiuping Pan (Raleigh, North Carolina);  Reynaldo Nuqui (Cary, North Carolina);  Anil Kondabathini (Cary, North Carolina)
ABSTRACT Technologies for providing secure emergency power control of a high voltage direct current transmission (HVDC) system include a controller. The controller includes circuitry configured to receive status data indicative of a present physical status of a power system. The circuitry is also configured to obtain an emergency power control command triggered by a remote source. The emergency power control command is to be executed by an HVDC transmission system of the power system. Further, the circuitry is configured to determine, as a function of the status data, whether the emergency power control command is consistent with the present physical status of the power system and block, in response to a determination that the emergency power control command is not consistent with the present physical status of the power system, execution of the emergency power control command by the HVDC transmission system.
FILED Monday, October 01, 2018
APPL NO 16/148043
ART UNIT 2839 — Multiplex and VoIP
CURRENT CPC
Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 3/001 (20200101)
H02J 3/36 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/1416 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11477412 Bianco et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) New York University (New York, New York)
ASSIGNEE(S) NEW YORK UNIVERSITY (New York, New York)
INVENTOR(S) Federica B. Bianco (New York, New York);  Gregory G. Dobler (New York, New York);  Steven E. Koonin (Cold Spring, New York)
ABSTRACT An exemplary system, method, and computer-accessible medium for determining a property(ies) regarding an electrical grid(s) can be provided, which can include, for example, receiving a video(s) of the electrical grid(s), determining a flicker(s) in the electrical grid(s) based on the video(s), and determining the property(ies) based on the flicker(s). The flicker(s) can be a 120 Hertz flicker. The flicker(s) can be a flicker in a light(s) recorded in the video(s). A frequency and a phase of the flicker(s) can be determined.
FILED Wednesday, September 25, 2019
APPL NO 16/581966
ART UNIT 2422 — Cable and Television
CURRENT CPC
Image Data Processing or Generation, in General
G06T 5/002 (20130101)
G06T 5/10 (20130101)
G06T 5/20 (20130101)
G06T 7/33 (20170101)

Pictorial Communication, e.g Television
H04N 7/0132 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 11471056 Lee et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) Lumicell, Inc. (Wellesley, Massachusetts)
ASSIGNEE(S) Lumicell, Inc. (Newton, Massachusetts)
INVENTOR(S) W. David Lee (Brookline, Massachusetts);  Jorge Ferrer (Arlington, Massachusetts);  David B. Strasfeld (Cambridge, Massachusetts)
ABSTRACT Embodiments related to medical imaging devices including rigid imaging tips and their methods of use for identifying abnormal tissue within a surgical bed are disclosed.
FILED Monday, July 11, 2016
APPL NO 15/206754
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0071 (20130101)
A61B 5/0075 (20130101)
A61B 5/0086 (20130101)
A61B 5/0091 (20130101) Original (OR) Class
A61B 5/4312 (20130101)
A61B 5/6886 (20130101)
A61B 10/0041 (20130101)
A61B 90/361 (20160201)
A61B 2090/306 (20160201)
A61B 2090/309 (20160201)
A61B 2090/3616 (20160201)
A61B 2090/3941 (20160201)
A61B 2505/05 (20130101)
A61B 2560/0431 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 49/0032 (20130101)
A61K 49/0056 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471260 MacEwan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S) Washington University (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Matthew R. MacEwan (St. Louis, Missouri);  Jingwei Xie (St. Louis, Missouri);  Zack Ray (St. Louis, Missouri);  Younan Xia (St. Louis, Missouri)
ABSTRACT A multi-laminar electrospun nanofiber scaffold for use in repairing a defect in a tissue substrate is provided. The scaffold includes a first layer formed by a first plurality of electrospun polymeric fibers, and a second layer formed by a second plurality of electrospun polymeric fibers. The second layer is combined with the first layer. A first portion of the scaffold includes a higher density of fibers than a second portion of the scaffold, and the first portion has a higher tensile strength than the second portion. The scaffold is configured to degrade via hydrolysis after at least one of a predetermined time or an environmental condition. The scaffold is configured to be applied to the tissue substrate containing the defect, and is sufficiently flexible to facilitate application of the scaffold to uneven surfaces of the tissue substrate, and to enable movement of the scaffold by the tissue substrate.
FILED Tuesday, October 27, 2020
APPL NO 17/081228
ART UNIT 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/02 (20130101) Original (OR) Class
A61F 2/0063 (20130101)
A61F 2/105 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 15/22 (20130101)
A61L 15/42 (20130101)
A61L 27/14 (20130101)
A61L 27/50 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 48/05 (20190201)
B29C 48/142 (20190201)

Apparatus for Enzymology or Microbiology;
C12M 25/14 (20130101)

Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons
D01D 5/0076 (20130101)
D01D 5/0092 (20130101)

Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding
D04H 1/728 (20130101)
D04H 3/016 (20130101)
D04H 3/073 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471314 Yangyuenthanasan et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  U.S. Bionics, Inc. (Emeryville, California)
INVENTOR(S) Theerapat Yangyuenthanasan (Berkeley, California);  Wayne Tung (Berkeley, California);  Homayoon Kazerooni (Berkeley, California)
ABSTRACT A trunk supporting exoskeleton comprises: a supporting trunk; thigh links configured to move in unison with a wearer's thighs; and first and second torque generators located on both left and right halves of the wearer substantially close to the wearer's hip. The torque generators couple the supporting trunk to the thigh links, and generate torque between the thigh links and the supporting trunk. When the wearer bends forward such that a predetermined portion of the supporting trunk passes beyond a predetermined angle from vertical, a torque generator(s) imposes a resisting torque between the supporting trunk and the thigh link(s), causing the supporting trunk to impose a force against the wearer's trunk, and the thigh link(s) to impose a force onto the wearer's thigh. When the predetermined portion does not pass beyond the predetermined angle, the torque generators impose no resisting torques between said supporting trunk and respective thigh links.
FILED Thursday, March 21, 2019
APPL NO 16/360969
ART UNIT 3785 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 5/026 (20130101) Original (OR) Class
A61F 5/028 (20130101)
A61F 2005/0179 (20130101)

Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body
A61H 1/0244 (20130101)
A61H 1/0292 (20130101)
A61H 3/008 (20130101)
A61H 2003/007 (20130101)
A61H 2201/164 (20130101)
A61H 2201/165 (20130101)
A61H 2201/1246 (20130101)
A61H 2201/1261 (20130101)
A61H 2201/1619 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471335 Jabbarzadeh et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
APPLICANT(S) UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina)
ASSIGNEE(S) University of South Carolina (Columbia, South Carolina)
INVENTOR(S) Ehsan Jabbarzadeh (Columbia, South Carolina);  Sara Eslambolchimoghadam (Columbia, South Carolina)
ABSTRACT Wound dressings, methods for forming the wound dressings, and methods for using the wound dressings are described. Wound dressings include a crosslinked hydrogel matrix and a plurality of porous absorbent microspheres encapsulated in the crosslinked matrix. The hydrogel matrix and the microspheres can include the same or different hydrogel polymers, e.g., alginates or the like. The wound dressings can be used in treating chronic wounds and burn wounds and can promote autolytic debridement.
FILED Tuesday, August 13, 2019
APPL NO 16/539192
ART UNIT 3786 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 13/00068 (20130101)
A61F 13/0213 (20130101) Original (OR) Class
A61F 13/0223 (20130101)
A61F 2013/530802 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 15/28 (20130101)
A61L 15/60 (20130101)
A61L 15/325 (20130101)
A61L 15/425 (20130101)
A61L 27/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471565 Alsberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio);  WORCESTER POLYTECHNIC INSTITUTE (Worcester, Massachusetts)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio);  WORCESTER POLYTECHNIC INSTITUTE (Worcester, Massachusetts)
INVENTOR(S) Eben Alsberg (Cleveland, Ohio);  Anna D. Dikina (Cleveland, Ohio);  Marsha W. Rolle (Worcester, Massachusetts)
ABSTRACT A modular engineered tissue construct includes a plurality of fused self-assembled, scaffold-free, high-density cell aggregates. At least one cell aggregate includes a plurality of cells and a plurality of biocompatible and biodegradable nanoparticles and/or microparticles that are incorporated within the cell aggregates. The nanoparticles and/or microparticles acting as a bulking agent within the cell aggregate to increase the cell aggregate size and/or thickness and improve the mechanical properties of the cell aggregate as well as to deliver bioactive agents.
FILED Monday, March 09, 2015
APPL NO 15/258666
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/54 (20130101)
A61L 27/3804 (20130101)
A61L 27/3882 (20130101) Original (OR) Class
A61L 2300/62 (20130101)
A61L 2300/414 (20130101)
A61L 2300/602 (20130101)
A61L 2400/12 (20130101)
A61L 2430/22 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0075 (20130101)
C12N 2513/00 (20130101)
C12N 2531/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471597 Lamrani et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona)
ASSIGNEE(S) Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) Imane Lamrani (Phoenix, Arizona);  Ayan Banerjee (Gilbert, Arizona);  Sandeep Gupta (Phoenix, Arizona)
ABSTRACT Methods and systems for utilizing co-simulation of a physical model and a self-adaptive predictive controller using hybrid automata are described. For example, there is disclosed a self-adaptive predictive control system to generate an initial patient model with initial patient model settings (k1, k2, . . . , kn) and execute a program that takes as input, the initial patient model settings as configuration parameters that specify at least a plurality of initial states. Such a system further receives new patient inputs and generates hybrid automata as a variation of the initial states by applying the new patient inputs to the initial patient model. The system further derives reachable states from the hybrid automata and outputs all reachable states computed. The system further detects changes and responsively generates a new patient predictive model with new parameter settings (k′1, k′2, . . . , k′n), iteratively repeating until a termination criterion is satisfied. Other related embodiments are disclosed.
FILED Friday, October 04, 2019
APPL NO 16/593337
ART UNIT 2184 — Computer Architecture and I/O
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 5/1723 (20130101) Original (OR) Class
A61M 2202/07 (20130101)
A61M 2205/50 (20130101)
A61M 2205/52 (20130101)
A61M 2230/201 (20130101)

Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 13/042 (20130101)
G05B 13/048 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 20/17 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471868 Liebeskind et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Emory University (Atlanta, Georgia)
ASSIGNEE(S) Emory University (Atlanta, Georgia)
INVENTOR(S) Lanny Steven Liebeskind (Atlanta, Georgia);  Pavan Kumar Reddy Gangireddy (Stone Mountain, Georgia)
ABSTRACT This disclosure relates to synthetic coupling methods using catalytic molecules. In certain embodiments, the catalytic molecules comprise heterocyclic thiolamide, S-acylthiosalicylamide, disulfide, selenium containing heterocycle, diselenide compound, ditelluride compound or tellurium containing heterocycle. Catalytic molecules disclosed herein are useful as catalysts in the transformation of hydroxy group containing compounds to amides, esters, ketones, and other carbon to heteroatom or carbon to carbon transformations
FILED Friday, October 09, 2020
APPL NO 17/067386
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 27/122 (20130101)
B01J 31/26 (20130101) Original (OR) Class
B01J 31/181 (20130101)
B01J 31/0218 (20130101)
B01J 31/0271 (20130101)
B01J 31/2269 (20130101)
B01J 2231/64 (20130101)
B01J 2231/4283 (20130101)
B01J 2531/16 (20130101)

Acyclic or Carbocyclic Compounds
C07C 231/02 (20130101)

Heterocyclic Compounds
C07D 275/04 (20130101)
C07D 293/06 (20130101)
C07D 293/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471935 Han
FUNDED BY
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Qingyou Han (West Lafayette, Indiana)
ASSIGNEE(S)
INVENTOR(S) Qingyou Han (West Lafayette, Indiana)
ABSTRACT A method of forming high quality metallurgical bonds in a composite casting is provided. The bonding technology includes the step of introducing a liquid material to contact the solid components placed in a mold cavity, applying an external field to generate stifling near the solid/liquid interface to wash off bubbles and oxide particles that prevent the liquid material from reacting to the solid component, and causing progressive solidification from the surfaces of the solid component to the liquid to drive away bubbles in the mushy zone near the bonding region. High quality metallurgical bonds are formed within the composite casting after the liquid solidifies. The resultant large composite casting has minimal defects, such as pores and oxides, at the interfaces between the solidified material and the solid objects.
FILED Wednesday, July 01, 2020
APPL NO 16/919054
ART UNIT 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Casting of Metals; Casting of Other Substances by the Same Processes or Devices
B22D 11/115 (20130101) Original (OR) Class
B22D 21/04 (20130101)

Alloys
C22C 21/02 (20130101)
C22C 23/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471939 Xia et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Younan Xia (Seattle, Washington);  Yugang Sun (Champaign, Illinois)
ABSTRACT Methods for forming nanostructures of various shapes are disclosed. Nanocubes, nanowires, nanopyramids and multiply twinned particles of silver may by formed by combining a solution of silver nitrate in ethylene glycol with a solution of poly(vinyl pyrrolidone) in ethylene glycol. Hollow nanostructures may be formed by reacting a solution of solid nanostructures comprising one of a first metal and a first metal alloy with a metal salt that can be reduced by the first metal or first metal alloy. Nanostructures comprising a core with at least one nanoshell may be formed by plating a nanostructure and reacting the plating with a metal salt.
FILED Monday, July 01, 2019
APPL NO 16/459407
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/0003 (20130101)
B22F 1/0007 (20130101) Original (OR) Class
B22F 1/054 (20220101)
B22F 1/062 (20220101)
B22F 1/065 (20220101)
B22F 1/0547 (20220101)
B22F 1/0549 (20220101)
B22F 1/0553 (20220101)
B22F 1/0655 (20220101)
B22F 9/24 (20130101)
B22F 2009/245 (20130101)
B22F 2301/255 (20130101)
B22F 2304/05 (20130101)
B22F 2998/00 (20130101)
B22F 2998/00 (20130101)
B22F 2998/00 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 977/896 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471980 Qiao et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) Jie Qiao (Rochester, New York);  Lauren L. Taylor (Medford, New Jersey)
ASSIGNEE(S) Rochester Institute of Technology (Rochester, New York)
INVENTOR(S) Jie Qiao (Rochester, New York);  Lauren L. Taylor (Medford, New Jersey)
ABSTRACT The disclosure relates to methods and systems incorporating physical modeling to identify the ultrafast laser/material interaction mechanisms and the impact of laser parameters, to optimize implementation of ultrafast laser-based processing for a given material. The process determines a laser fluence near the ablation threshold for a given material and given pulse duration. The repetition rate, scanning speed and scanning strategy are subsequently optimized to minimize heat accumulation, having an operable line scan overlap between 50% to 85% for achieving smooth ultrafast-laser polishing, while maintaining an optic-quality surface.
FILED Friday, August 21, 2020
APPL NO 16/999891
ART UNIT 3761 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 2018/00577 (20130101)
A61B 2018/00625 (20130101)

Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 26/36 (20130101)
B23K 26/40 (20130101) Original (OR) Class
B23K 26/073 (20130101)
B23K 26/082 (20151001)
B23K 26/354 (20151001)
B23K 26/0624 (20151001)
B23K 26/3576 (20180801)
B23K 2103/52 (20180801)
B23K 2103/54 (20180801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11472089 Pandey et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) Vivek Pandey (Cleveland, Ohio);  Sidney Carson (Cleveland, Ohio);  Joao Maia (Shaker Heights, Ohio)
ABSTRACT A mixing element for an extruder screw having a width extending in an x-direction of an x-y-z coordinate system, a length extending in a y-direction, and a thickness extending in a z-direction. The mixing element includes a base defining a passage extending along an axis in the y-direction for receiving the extruder screw. Projections extend radially outward from the base and define channels therebetween. The width and the depth of each channel vary along the length of the channel.
FILED Monday, May 06, 2019
APPL NO 16/404339
ART UNIT 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 48/62 (20190201) Original (OR) Class
B29C 48/67 (20190201)
B29C 48/68 (20190201)
B29C 48/565 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11472847 Fox et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) The Regents of the University of Colorado (Denver, Colorado)
ASSIGNEE(S) The Regents of the University of Colorado (Denver, Colorado)
INVENTOR(S) Jerome Fox (Boulder, Colorado);  Ankur Sarkar (Boulder, Colorado);  Akarawin Hongdusit (Boulder, Colorado);  Edward Kim (Oakland, California)
ABSTRACT This invention relates to the field of genetic engineering. Specifically, the invention relates to the construction of operons to produce biologically active agents. For example, operons may be constructed to produce agents that control the function of biochemical pathway proteins (e.g., protein phosphatases, kinases and/or proteases). Such agents may include inhibitors and modulators that may be used in studying or controlling phosphatase function associated with abnormalities in a phosphatase pathway or expression level. Fusion proteins, such as light activated protein phosphatases, may be genetically encoded and expressed as photoswitchable phosphatases. Systems are provided for use in controlling phosphatase function within living cells or in identifying small molecule inhibitors/activator/modulator molecules of protein phosphatases associated with cell signaling.
FILED Tuesday, January 05, 2021
APPL NO 17/141321
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 14/005 (20130101) Original (OR) Class
C07K 14/47 (20130101)
C07K 2319/80 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/20 (20130101)

Enzymes
C12Y 205/0101 (20130101)
C12Y 205/01001 (20130101)
C12Y 207/01036 (20130101)
C12Y 207/04002 (20130101)
C12Y 301/01048 (20130101)
C12Y 401/01033 (20130101)
C12Y 402/03017 (20130101)
C12Y 402/03018 (20130101)
C12Y 402/03024 (20130101)
C12Y 402/03056 (20130101)
C12Y 503/03002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11472915 Swager et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Timothy M. Swager (Newton, Massachusetts);  Yuan He (Cambridge, Massachusetts);  Zachary Smith (Belmont, Massachusetts);  Sharon Lin (Somerville, Massachusetts);  Francesco Maria Benedetti (Urbania, Italy)
ABSTRACT Porous compositions such as flexible polymers with side chain porosity are generally provided. In some embodiments, the composition comprises a flexible polymer backbone and a plurality of rigid side chains. In some embodiments, the rigid side chains form pores. In some embodiments, the rigid side chains may comprise two or more [2.2.2] bicyclic cores (e.g., formed by a ring opening metathesis polymerization. The compounds and methods described herein may be useful in various applications including, for example, gas separation.
FILED Friday, June 07, 2019
APPL NO 16/435397
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Separation
B01D 53/228 (20130101)
B01D 71/28 (20130101)
B01D 71/44 (20130101)
B01D 2325/02 (20130101)
B01D 2325/20 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 61/08 (20130101) Original (OR) Class
C08G 2261/3324 (20130101)
C08G 2261/3325 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11473004 Goual et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) University of Wyoming (Laramie, Wyoming)
ASSIGNEE(S) UNIVERSITY OF WYOMING (Laramie, Wyoming)
INVENTOR(S) Lamia Goual (Laramie, Wyoming);  Tianzhu Qin (Laramie, Wyoming);  Gina Javanbakht (Laramie, Wyoming);  Mohammad Piri (Laramie, Wyoming)
ABSTRACT Novel microemulsion formulations comprising a surfactant or combination of surfactants are disclosed for improved crude oil cleanup or recovery from subsurface geological formations, especially those containing carbonate cements.
FILED Friday, December 02, 2016
APPL NO 15/367478
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 8/524 (20130101)
C09K 8/584 (20130101) Original (OR) Class

Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells
E21B 43/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11473205 Choi et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Kyoung-Shin Choi (Fitchburg, Wisconsin);  Stephen Riley Kubota (Madison, Wisconsin)
ABSTRACT Methods for electrochemically oxidizing aromatic aldehydes, such as furfural and furfural derivatives, to carboxylic acids in acidic solutions are provided. Also provided are electrochemical cells for carrying out the oxidation reactions. The electrochemical oxidations may be conducted in aqueous media at ambient pressure and mild temperatures.
FILED Tuesday, September 14, 2021
APPL NO 17/474286
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 3/23 (20210101) Original (OR) Class
C25B 11/04 (20130101)
C25B 11/054 (20210101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11473818 Goldfarbmuren et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) Rebound Technologies, Inc. (Commerce City, Colorado)
ASSIGNEE(S) Rebound Technologies, Inc. (Commerce City, Colorado)
INVENTOR(S) Russell Goldfarbmuren (Denver, Colorado);  Luke Erickson (Denver, Colorado)
ABSTRACT Methods, systems, and device for cycle enhancement are provided in accordance with various embodiments. Various embodiments generally pertain to refrigeration and heat pumping. Different embodiments may be applied to a variety of heat pump architectures. Some embodiments may integrate with vapor compression heat pumps in industrial, commercial, and/or residential applications. Some embodiments include a method that may include at least: removing a first heat from a vapor compression cycle; utilizing the first removed heat from the vapor compression cycle to drive a thermally driven heat pump; or removing a second heat from the vapor compression cycle utilizing the thermally driven heat pump to reduce a temperature of a refrigerant of the vapor compression cycle below an ambient temperature.
FILED Monday, March 09, 2020
APPL NO 16/813023
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems
F25B 1/10 (20130101)
F25B 5/02 (20130101)
F25B 9/14 (20130101)
F25B 25/02 (20130101)
F25B 25/005 (20130101)
F25B 30/06 (20130101) Original (OR) Class
F25B 40/02 (20130101)
F25B 40/04 (20130101)
F25B 41/31 (20210101)
F25B 2400/05 (20130101)
F25B 2400/13 (20130101)
F25B 2500/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11474127 Coe et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
ASSIGNEE(S) RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey)
INVENTOR(S) Angela Coe (Tenstrike, Minnesota);  Guohong Li (Highland Park, New Jersey);  Eva Y. Andrei (Highland Park, New Jersey)
ABSTRACT An apparatus, including: a scanning probe microscope head with a frame configured to fit within an insert of a cryostat, and a scanner, a probe and a sample holder all disposed within the frame; and a coarse motor assembly disposed within the frame and comprising: a positionable component; and coarse motors. The coarse motors are configured to move the positionable component relative to the frame along an X axis, a Y axis, and a Z axis. The apparatus further includes a universal electrical base connection with half of a plug/socket arrangement. The plug/socket arrangement is configured to provide electrical communication between the scanning probe microscope head and a base which has a second half of the plug/socket arrangement when the scanning probe microscope head is lowered onto the base.
FILED Thursday, May 06, 2021
APPL NO 17/313743
ART UNIT 2881 — Optics
CURRENT CPC
Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM]
G01Q 10/02 (20130101)
G01Q 30/20 (20130101)
G01Q 70/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11474145 Ugur et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Enes Ugur (Richardson, Texas);  Bilal Akin (Richardson, Texas);  Fei Yang (Plano, Texas);  Shi Pu (Plano, Texas);  Chi Xu (Plano, Texas)
ABSTRACT Embodiments according to the invention can provide methods of testing a SiC MOSFET, that can include applying first and second voltage levels across a gate-source junction of a SiC MOSFET and measuring first and second voltage drops across a reverse body diode included in the SiC MOSFET responsive to the first and second voltage levels, respectively, to provide an indication of a degradation of a gate oxide of the SiC MOSFET and an indication of contact resistance of the SiC MOSFET, respectively.
FILED Wednesday, June 10, 2020
APPL NO 16/897719
ART UNIT 2866 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/2601 (20130101)
G01R 31/2621 (20130101)
G01R 31/2642 (20130101) Original (OR) Class
G01R 31/2644 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11474531 Reiserer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Institute of Child Health and Human Development (NICHD)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
APPLICANT(S) VANDERBILT UNIVERSITY (Nashville, Tennessee)
ASSIGNEE(S) VANDERBILT UNIVERSITY (Nashville, Tennessee)
INVENTOR(S) Ronald S. Reiserer (Nashville, Tennessee);  John P. Wikswo (Brentwood, Tennessee)
ABSTRACT A robot for transporting a biodevice from one place to another place, comprising a body for carrying the biodevice; a driving assembly for driving the body in omnidirectional motion; a sensing unit for sensing at least a position and orientation of the body; and a control unit coupled to the driving assembly and the sensing unit for generating one or more control signals based on at least the sensed position and orientation of the body to drive the driving assembly so as to move the body to a desired place and to arrive with the correct orientation.
FILED Wednesday, January 19, 2022
APPL NO 17/578779
ART UNIT 1799 — Optics
CURRENT CPC
Vehicle Wheels; Castors; Axles for Wheels or Castors; Increasing Wheel Adhesion
B60B 19/003 (20130101)

Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles
B60L 53/12 (20190201)

Apparatus for Enzymology or Microbiology;
C12M 23/44 (20130101)
C12M 23/50 (20130101)
C12M 23/52 (20130101)
C12M 29/10 (20130101)
C12M 41/48 (20130101)

Systems for Controlling or Regulating Non-electric Variables
G05D 1/0225 (20130101) Original (OR) Class
G05D 1/0291 (20130101)
G05D 1/0891 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11474952 Annapareddy et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) The Texas A and M University System (College Station, Texas)
ASSIGNEE(S) The Texas A and M University System (College Station, Texas);  Hewlett Packard Enterprise Development LP (Houston, Texas)
INVENTOR(S) Narasimha Reddy Annapareddy (College Station, Texas);  Chih-Chieh Chou (San Jose, California);  Chandrahas Tirumulasetty (Bryan, Texas);  Paul Gratz (College Station, Texas);  Ayman Abouelwafa (Folsom, California)
ABSTRACT Methods, systems, and computer readable media for performing page fault handling are disclosed. According to one method, the method includes: after a translation lookaside buffer (TLB) miss associated with a virtual memory page occurs, identifying, in a page table, a page table entry (PTE) associated with the virtual memory page; determining, using a first indicator in the PTE, that the virtual memory page is not present in a main memory; determining, using a second indicator in the PTE, that the virtual memory page is associated with a valid memory address and that the virtual memory page is capable of using pre-allocated pages; obtaining, from a pre-allocation table, a page frame number associated with a pre-allocated page; and updating the PTE to indicate the page frame number.
FILED Tuesday, June 01, 2021
APPL NO 17/335936
ART UNIT 2133 — Memory Access and Control
CURRENT CPC
Electric Digital Data Processing
G06F 12/0223 (20130101)
G06F 12/1027 (20130101) Original (OR) Class
G06F 2212/657 (20130101)
G06F 2212/684 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11475288 Najafi et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Mohammadhassan Najafi (Lafayette, Louisiana);  David J. Lilja (Maplewood, Minnesota);  Marcus Riedel (Shorewood, Minnesota);  Kiarash Bazargan (Plymouth, Minnesota)
ABSTRACT Various implementations of sorting networks are described that utilize time-encoded data signals having encoded values. In some examples, an electrical circuit device includes a sorting network configured to receive a plurality of time-encoded signals. Each time-encoded signal of the plurality of time-encoded signals encodes a data value based on a duty cycle of the respective time-encoded signal or based on a proportion of data bits in the respective time-encoded signal that are high relative to the total data bits in the respective time-encoded signal. The sorting network is also configured to sort the plurality of time-encoded signals based on the encoded data values of the plurality of time-encoded signals.
FILED Tuesday, November 05, 2019
APPL NO 16/674488
ART UNIT 2182 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 7/20 (20130101)
G06F 7/24 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/0635 (20130101) Original (OR) Class

Coding; Decoding; Code Conversion in General
H03M 1/504 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11475536 Liu et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) Portland State University (Portland, Oregon)
ASSIGNEE(S) PORTLAND STATE UNIVERSITY (Portland, Oregon)
INVENTOR(S) Feng Liu (Portland, Oregon);  Simon Niklaus (Portland, Oregon)
ABSTRACT Systems, methods, and computer-readable media for context-aware synthesis for video frame interpolation are provided. Bidirectional flow may be used in combination with flexible frame synthesis neural network to handle occlusions and the like, and to accommodate inaccuracies in motion estimation. Contextual information may be used to enable frame synthesis neural network to perform informative interpolation. Optical flow may be used to provide initialization for interpolation. Other embodiments may be described and/or claimed.
FILED Friday, February 22, 2019
APPL NO 16/971478
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 5/046 (20130101)

Image Data Processing or Generation, in General
G06T 3/0093 (20130101) Original (OR) Class
G06T 3/4007 (20130101)
G06T 5/50 (20130101)
G06T 2207/20081 (20130101)
G06T 2207/20084 (20130101)
G06T 2207/20224 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11475651 Huo et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Ke Huo (West Lafayette, Indiana);  Vinayak Raman Krishnamurthy (West Lafayette, Indiana);  Karthik Ramani (West Lafayette, Indiana)
ABSTRACT A virtual reality system, comprising an electronic 2d interface having a depth sensor, the depth sensor allowing a user to provide input to the system to instruct the system to create a virtual 3D object in a real-world environment. The virtual 3D object is created with reference to at least one external physical object in the real-world environment, with the external physical object concurrently displayed with the virtual 3D object by the interface. The virtual 3D object is based on physical artifacts of the external physical object.
FILED Thursday, April 02, 2020
APPL NO 16/838890
ART UNIT 2623 — Selective Visual Display Systems
CURRENT CPC
Electric Digital Data Processing
G06F 3/041 (20130101)
G06F 3/0482 (20130101)
G06F 3/03545 (20130101)
G06F 3/04815 (20130101)
G06F 3/04883 (20130101)
G06F 2203/04104 (20130101)
G06F 2203/04808 (20130101)

Image Data Processing or Generation, in General
G06T 7/13 (20170101)
G06T 7/40 (20130101)
G06T 15/04 (20130101)
G06T 17/20 (20130101)
G06T 19/006 (20130101)
G06T 19/20 (20130101) Original (OR) Class
G06T 2207/10028 (20130101)
G06T 2219/2004 (20130101)
G06T 2219/2016 (20130101)
G06T 2219/2021 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11476464 Li et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Wenzhi Li (Miami, Florida);  Arun Thapa (Miami, Florida)
ASSIGNEE(S) THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S) Wenzhi Li (Miami, Florida);  Arun Thapa (Miami, Florida)
ABSTRACT Vertically aligned carbon nanotubes (VACNTs) (e.g., multi-walled VACNTs and methods of synthesizing the same are provided. VACNTs can be synthesized on nickel foam (Ni—F), for example by using a plasma-enhanced chemical vapor deposition (PECVD) technique. A wet chemical method can then be used to coat on the VACNTs a layer of nanoparticles, such as tin oxide (SnO2) nanoparticles.
FILED Friday, September 10, 2021
APPL NO 17/471313
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/38 (20130101)
H01M 4/48 (20130101)
H01M 4/366 (20130101)
H01M 4/0428 (20130101)
H01M 4/583 (20130101) Original (OR) Class
H01M 10/0525 (20130101)
H01M 2004/021 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11476495 Archer et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) Cornell University (Ithaca, New York)
ASSIGNEE(S) CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S) Lynden A. Archer (Ithaca, New York);  Shuya Wei (Henan, China PRC)
ABSTRACT A sodium-ion conducting (e.g., sodium-sulfur) battery, which can be rechargeable, comprising a microporous host-sulfur composite cathode as described herein or a liquid electrolyte comprising a liquid electrolyte solvent and a liquid electrolyte salt or electrolyte additive as described herein or a combination thereof. The batteries can be used in devices such as, for example, battery packs.
FILED Friday, August 21, 2020
APPL NO 16/999484
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/13 (20130101)
H01M 4/38 (20130101)
H01M 4/362 (20130101)
H01M 4/381 (20130101)
H01M 4/624 (20130101)
H01M 10/054 (20130101) Original (OR) Class
H01M 10/0567 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11476673 Sarwat et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Arif I. Sarwat (Miami, Florida);  Temitayo O. Olowu (Miami, Florida)
ASSIGNEE(S) THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S) Arif I. Sarwat (Miami, Florida);  Temitayo O. Olowu (Miami, Florida)
ABSTRACT Systems, methods, and frameworks for distribution grid optimal power flow (D-OPF) are provided, to find the optimal droop and mode settings of smart inverters (SIs). The droop and mode settings of SIs can be found as per the Institute of Electrical and Electronics Engineers (IEEE)-1547 in coordination with the operations of legacy voltage control devices for optimal Volt-VAR control performance. The D-OPF framework can utilize two timescale coordination of control of legacy grid voltage control devices, modes and droop settings of SIs, and active/reactive power dispatch of SIs.
FILED Tuesday, May 03, 2022
APPL NO 17/661785
ART UNIT 2119 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 19/042 (20130101)
G05B 2219/2639 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 3/24 (20130101) Original (OR) Class
H02J 3/381 (20130101)
H02J 2300/24 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11476778 Li et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Basic Energy Sciences (BES)
National Science Foundation (NSF)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Anyin Li (Atlanta, Georgia);  Facundo Martin Fernandez (Atlanta, Georgia);  Yunlong Zi (Atlanta, Georgia)
ABSTRACT An ion pulse generator (100) includes a triboelectric generator (110), an ion emitter (132) and a conductive surface (134). The triboelectric generator (110) includes a first electrode (114), a spaced apart second electrode (120) and a first triboelectric layer (116). The triboelectric generator (110) generates a predetermined amount of charge as a result of relative movement of the first triboelectric layer (116). The ion emitter (132) is electrically coupled to the first electrode (114). The conductive surface (134) is electrically coupled to the second electrode (120) and is spaced apart from the ion emitter (132) at a predetermined distance. Generation of the predetermined amount of charge causes formation of ions between the ion emitter (132) and the conductive surface (134).
FILED Tuesday, September 12, 2017
APPL NO 16/645269
ART UNIT 2881 — Optics
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 49/10 (20130101)
H01J 49/26 (20130101)
H01J 49/165 (20130101)
H01J 49/167 (20130101)
H01J 49/168 (20130101)

Electric Machines Not Otherwise Provided for
H02N 1/004 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 11473153 Atencia-Fernandez
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland)
ASSIGNEE(S) UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland)
INVENTOR(S) Francisco Javier Atencia-Fernandez (Bethesda, Maryland)
ABSTRACT The present disclosure relates to devices and systems for separating motile pathogenic bacterial cells from samples. The disclosure also provides for methods of determining whether a sample is contaminated by pathogenic bacteria. The devices and systems disclosed herein are useful for screening water sources, environmental testing sites, food sources, and bodily fluids for the presence, absence, or quantity of bacterial cells in a sample representative of the screened sources.
FILED Tuesday, June 02, 2015
APPL NO 15/315978
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502753 (20130101)
B01L 2200/0689 (20130101)
B01L 2200/0694 (20130101)
B01L 2300/12 (20130101)
B01L 2300/165 (20130101)
B01L 2300/0681 (20130101)
B01L 2300/0816 (20130101)
B01L 2300/0864 (20130101)
B01L 2400/0472 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/689 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/06 (20130101)
G01N 15/1056 (20130101)
G01N 2015/1006 (20130101)
G01N 2015/1081 (20130101)
G01N 2015/1486 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11474134 Rigosi
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland)
ASSIGNEE(S) GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland)
INVENTOR(S) Albert Felix Rigosi (Rockville, Maryland)
ABSTRACT A gateless P-N junction metrolog includes: a junction member including: a p-interface; and an n-interface disposed laterally and adjacent to the p-interface; and a p-n junction disposed at where the p-interface and n-interface contact; a drain electrode disposed on the junction member; a source electrode disposed on the junction member such that the source electrode is spaced apart from and opposing the drain electrode; an n-polymer disposed on the n-interface of the junction member; a p-polymer disposed on the p-interface of the junction member such that the n-polymer is interposed between the p-polymer and the n-interface; a mediation polymer disposed on the p-polymer such that the p-polymer is interposed between the mediation polymer and the junction member; and a mediator disposed in the mediation polymer and that receives electrons from the junction member in forming the p-interface.
FILED Monday, November 04, 2019
APPL NO 16/672613
ART UNIT 2867 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 27/14 (20130101) Original (OR) Class

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 29/24 (20130101)
H01L 29/1606 (20130101)
H01L 29/7606 (20130101)
H01L 29/66977 (20130101)
H01L 43/065 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11475168 Tehranipoor et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida)
INVENTOR(S) Mark M. Tehranipoor (Gainesville, Florida);  Adib Nahiyan (Gainesville, Florida);  Domenic J. Forte (Gainesville, Florida);  Jungmin Park (Gainesville, Florida)
ABSTRACT Various examples are provided related to power side-channel vulnerability assessment. In one example, a method includes identifying target registers in an IC design; generating input patterns associated with a target function that can generate a power difference in the target registers when processing the target function; determining a side-channel vulnerability (SCV) metric using the power difference produced by the input patterns; and identifying a vulnerability in the IC design using the SCV metric. Identification of the vulnerability allows for modification of the IC design at an early stage, which can avoid power side-channel attacks (e.g., DPA and CPA) in the fabricated IC design. The method can be used for pre-silicon power side-channel leakage assessment of IC designs such as, e.g., cryptographic and non-cryptographic circuits.
FILED Tuesday, July 23, 2019
APPL NO 16/520002
ART UNIT 2439 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/755 (20170801) Original (OR) Class
G06F 30/30 (20200101)
G06F 2119/06 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11475185 Soles et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland)
ASSIGNEE(S) GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland)
INVENTOR(S) Christopher L. Soles (Boyds, Maryland);  Edwin Pak-Nin Chan (Rockville, Maryland);  Irmgard Bischofberger (Chicago, Illinois);  Sidney Robert Nagel (Chicago, Illinois);  Heinrich Martin Jaeger (Chicago, Illinois);  Juan Jose de Pablo (Chicago, Illinois);  Nidhi Pashine (Chicago, Illinois);  Daniel Robert Reid (Chicago, Illinois);  Carl Goodrich (Chicago, Illinois);  Andrea Jo-Wei Liu (Chicago, Illinois);  Daniel Hexner (Chicago, Illinois);  Marcos A. Reyes-Martinez (Washington, District of Columbia);  Meng Shen (Los Angeles, California)
ABSTRACT An inverse design machine for making a manufactured article that includes a designer Impact-mitigating architectured isotropic structure includes: an input unit that receives a primary structure; a primary structure analyzer that receives the primary structure from the input unit and determines primary properties of the primary structure; a structure adjuster that receives the primary properties from the primary structure analyzer, receives impact-mitigating properties from a structural property manager, and produces the designer Impact-mitigating architectured isotropic structure from the impact-mitigating properties; and the structural property manager that provides the impact-mitigating properties to the structure adjuster.
FILED Wednesday, April 01, 2020
APPL NO 16/837504
ART UNIT 2148 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 30/17 (20200101)
G06F 30/23 (20200101) Original (OR) Class
G06F 2101/02 (20130101)
G06F 2113/10 (20200101)
G06F 2119/14 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 11471461 Boden et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) Emory University (Atlanta, Georgia);  The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) Emory University (Atlanta, Georgia);  US Govt represented by Dept of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Scott D. Boden (Atlanta, Georgia);  Sreedhara Sangadala (Atlanta, Georgia)
ABSTRACT The disclosure relates to compounds and compositions for forming bone and methods related thereto. In one embodiment, the disclosure relates to a composition comprising a compound disclosed herein, such as 2,4-diamino-1,3,5-triazine derivatives or salts thereof, for use in bone growth processes. In a typical embodiment, a bone graft composition is implanted in a subject at a site of desired bone growth or enhancement.
FILED Tuesday, December 15, 2020
APPL NO 17/122853
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/53 (20130101) Original (OR) Class
A61K 31/53 (20130101)
A61K 38/1875 (20130101)
A61K 2300/00 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/54 (20130101)
A61L 2300/412 (20130101)
A61L 2430/02 (20130101)

Heterocyclic Compounds
C07D 251/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11474106 Henderson et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) ACCELERATED MEDICAL DIAGNOSTICS, INC. (Berkeley, California);  LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California);  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
INVENTOR(S) Paul Henderson (Berkeley, California);  George D. Cimino (Lafayette, California);  Chong-Xian Pan (Davis, California);  Ralph William de Vere White (Sacramento, California);  Maike Zimmermann (Davis, California);  Kenneth W. Turteltaub (Livermore, California)
ABSTRACT The invention relates to methods, systems and kits for determining therapeutic effectiveness or toxicity of cancer-treating compounds that incorporate into or bind to DNA. In particular, the invention is directed to methods, systems and kits for predicting a patient's treatment outcome after administration of a microdose of therapeutic composition to the patient. The methods provides physicians with a diagnostic tool to segregate cancer patients into differential populations that have a higher or lower chance of responding to a particular therapeutic treatment.
FILED Thursday, July 07, 2016
APPL NO 15/742454
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/28 (20130101)
A61K 31/395 (20130101)
A61K 31/555 (20130101)
A61K 31/555 (20130101)
A61K 31/7068 (20130101)
A61K 31/7068 (20130101)
A61K 33/24 (20130101)
A61K 33/243 (20190101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/60 (20130101)
G01N 33/96 (20130101)
G01N 33/5308 (20130101)
G01N 33/6848 (20130101)
G01N 33/57484 (20130101) Original (OR) Class
G01N 2800/52 (20130101)
G01N 2800/56 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US D967101 Cooper et al.
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia);  University of Pittsburgh Of The Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Rory A. Cooper (Gibsonia, Pennsylvania);  Garrett G. Grindle (Pittsburgh, Pennsylvania);  Zachary Kitzmiller Anzelone (Blairsville, Pennsylvania);  Aaron Tyler Anderson (Pittsburgh, Pennsylvania)
ABSTRACT
FILED Friday, July 31, 2020
APPL NO 29/744800
ART UNIT 2917 — Design
CURRENT CPC
Recording, communication, or information retrieval equipment
D14/410
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 11471940 Pu et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
National Aeronautics and Space Administration (NASA)
Merced Nanomaterials Center for Energy and Sensing (MACES)
NASA Shared Services Center (NSSC)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Ying-Chih Pu (Santa Cruz, California);  Frank Song (Santa Cruz, California);  Weichun Zhang (Santa Cruz, California);  Sarah Lindley (Santa Cruz, California);  Staci Adams (Santa Cruz, California);  Jin Zhang (Santa Cruz, California)
ABSTRACT Provided are methods of producing cobalt nanoparticles (Co NPs). The methods include combining a cobalt salt, a capping agent, and a reducing agent, under Co NP synthesis conditions including a temperature selected to produce cobalt nanoparticles of a pre-selected diameter, where the temperature and pre-selected diameter are inversely related. In certain aspects, the methods further include producing hollow gold nano spheres (HGNs) using the cobalt nanoparticles as scaffolds. Also provided are cobalt nanoparticles and hollow gold nano spheres (HGNs) produced according to the present methods. Kits that find use in practicing the methods of the present disclosure are also provided.
FILED Friday, December 01, 2017
APPL NO 16/465708
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/062 (20130101)

Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/054 (20220101) Original (OR) Class
B22F 1/0549 (20220101)
B22F 9/24 (20130101)
B22F 2301/15 (20130101)
B22F 2301/255 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11473663 Roberts et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Gary D. Roberts (Wadsworth, Ohio);  Robert F. Handschuh (North Olmsted, Ohio);  Kelsen E. LaBerge (Lakewood, Ohio);  Joel P. Johnston (Cleveland, Ohio);  Sandi G. Miller (Northfield, Ohio)
ABSTRACT A gear includes a steel rim having an inner circumferential surface a composite gear body attached thereto. The composite gear body includes an opening in a central region thereof. A first continuous fiber composite layer extends from a first point on an outer circumferential edge of the composite gear body to a second point on the outer circumferential edge. A second continuous fiber layer extends from the first point to the second point. The composite gear body also includes a filler layer disposed between the first and second continuous fiber layers, the filler layer extending within an inner region of the composite gear body. The inner region extends radially between the opening and a boundary inward of the inner circumferential surface such that the composite gear body is thicker within the inner region.
FILED Friday, February 22, 2019
APPL NO 16/283069
ART UNIT 3658 — Material and Article Handling
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 5/26 (20130101)

Gearing
F16H 55/06 (20130101) Original (OR) Class
F16H 55/17 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11476804 Quilligan et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) Gerard T. Quilligan (Gulf Breeze, Florida);  Terry Hurford (Greenbelt, Maryland)
ABSTRACT A clock source includes a comparator having a positive comparator input, a negative comparator input, a proportional to absolute temperature (PTAT) PMOS bias input, a PTAT NMOS bias input, and a comparator output, a resonator element, series and feedback resistors and other passive components coupled between the comparator output and the negative comparator input to generate a signal with approximately constant gain and frequency at the comparator output, and a PTAT bias circuit coupled to the comparator's PTAT PMOS and NMOS bias inputs, and configured to drive the PTAT PMOS bias input and the PTAT NMOS bias input to maintain approximately constant gain and frequency over the operating temperature range of the clock source.
FILED Monday, November 22, 2021
APPL NO 17/532689
ART UNIT 2849 — Optics
CURRENT CPC
Systems for Regulating Electric or Magnetic Variables
G05F 3/02 (20130101)

Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits
H03B 5/364 (20130101) Original (OR) Class
H03B 5/1228 (20130101)

Pulse Technique
H03K 3/011 (20130101)

Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses
H03L 1/00 (20130101)

Transmission
H04B 1/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 11471135 Park et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Small Business Technology Transfer (STTR)
APPLICANT(S) Intelligent Fiber Optic Systems, Inc. (Santa Clara, California)
ASSIGNEE(S) Intelligent Fiber Optic Systems, Inc. (San Jose, California)
INVENTOR(S) Yong-Lae Park (Stanford, California);  Richard James Black (Menlo Park, California);  Behzad Moslehi (Los Altos, California);  Mark R. Cutkosky (Stanford, California);  Santhi Elayaperumal (Stanford, California);  Bruce Daniel (Stanford, California);  Alan Yeung (Stanford, California);  Vahid Sotoudeh (Los Altos, California)
ABSTRACT A biopsy needle has a central axis and includes one or more sensing regions, each sensing region formed by a plurality of sensing optical fibers located over a particular extent of said central axis and inside the outer shell of the needle. The sensing optical fibers are coupled to a wavelength interrogator. A steerable catheter has a central axis and outer shell, the outer shell coupled to a plurality of optical fibers in sensing regions and actuation regions, the sensing regions formed over particular extents of the central axis by bonding gratings to the inner surface of the outer shell, and the actuation regions formed by coupling optical energy into shape memory alloys bonded to the outer shell.
FILED Monday, February 11, 2019
APPL NO 16/271883
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 10/0233 (20130101) Original (OR) Class
A61B 18/1492 (20130101)
A61B 90/06 (20160201)
A61B 2017/00057 (20130101)
A61B 2017/00867 (20130101)
A61B 2034/2061 (20160201)
A61B 2090/064 (20160201)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 25/0043 (20130101)
A61M 25/0105 (20130101)
A61M 25/0133 (20130101)
A61M 25/0158 (20130101)
A61M 2025/0166 (20130101)
A61M 2205/0266 (20130101)
A61M 2205/3306 (20130101)

Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 1/246 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11471935 Han
FUNDED BY
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Qingyou Han (West Lafayette, Indiana)
ASSIGNEE(S)
INVENTOR(S) Qingyou Han (West Lafayette, Indiana)
ABSTRACT A method of forming high quality metallurgical bonds in a composite casting is provided. The bonding technology includes the step of introducing a liquid material to contact the solid components placed in a mold cavity, applying an external field to generate stifling near the solid/liquid interface to wash off bubbles and oxide particles that prevent the liquid material from reacting to the solid component, and causing progressive solidification from the surfaces of the solid component to the liquid to drive away bubbles in the mushy zone near the bonding region. High quality metallurgical bonds are formed within the composite casting after the liquid solidifies. The resultant large composite casting has minimal defects, such as pores and oxides, at the interfaces between the solidified material and the solid objects.
FILED Wednesday, July 01, 2020
APPL NO 16/919054
ART UNIT 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Casting of Metals; Casting of Other Substances by the Same Processes or Devices
B22D 11/115 (20130101) Original (OR) Class
B22D 21/04 (20130101)

Alloys
C22C 21/02 (20130101)
C22C 23/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11473826 Closs et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Mitegen, LLC (Ithaca, New York)
ASSIGNEE(S) MiTeGen, LLC (Ithaca, New York)
INVENTOR(S) David Closs (Freeville, New York);  Stephen Hollabaugh (Ithaca, New York);  Robert E. Thorne (Ithaca, New York);  Robert Newman (Groton, New York);  Benjamin A. Apker (Ithaca, New York)
ABSTRACT A cryogenic cooling manifold and methods incorporating a cryogenic cooling manifold for managing the gas layer(s) above a liquid cryogen to control cooling temperature-time profiles and ice formation for microliter and smaller samples that are plunged through the gas and into the liquid cryogen.
FILED Wednesday, July 27, 2016
APPL NO 15/220868
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 1/0252 (20130101)

Refrigerators; Cold Rooms; Ice-boxes; Cooling or Freezing Apparatus Not Otherwise Provided for
F25D 3/10 (20130101) Original (OR) Class
F25D 2400/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 11477122 Flajslik et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) Intel Corporation (Santa Clara, California)
ASSIGNEE(S) Intel Corporation (Santa Clara, California)
INVENTOR(S) Mario Flajslik (Hopkinton, Massachusetts);  Eric R. Borch (Fort Collins, Colorado);  Timo Schneider (Hudson, Massachusetts);  Michael A. Parker (Santa Clara, California)
ABSTRACT Technologies for improving throughput in a network include a node switch. The node switch is to obtain expected performance data indicative of an expected data transfer performance of the node switch. The node switch is also to obtain measured performance data indicative of a measured data transfer performance of the node switch, compare the measured performance data to the expected performance data to determine whether the measured data transfer performance satisfies the expected data transfer performance, determine, as a function of whether the measured data transfer performance satisfies the expected data transfer performance, whether to force a unit of data through a non-minimal path to a destination, and send, in response to a determination to force the unit of data to be sent through a non-minimal path, the unit of data to an output port of the node switch associated with the non-minimal path. Other embodiments are also described.
FILED Wednesday, September 27, 2017
APPL NO 15/716831
ART UNIT 2476 — Multiplex and VoIP
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 41/0893 (20130101)
H04L 41/0896 (20130101)
H04L 43/0882 (20130101)
H04L 43/0888 (20130101)
H04L 43/0894 (20130101)
H04L 45/123 (20130101)
H04L 47/22 (20130101) Original (OR) Class
H04L 47/6255 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. State Government 

US 11476801 Hoff
FUNDED BY
U.S. State Government
State of California
California Public Utilities Commission (PUC)
APPLICANT(S) Clean Power Research, L.L.C. (Napa, California)
ASSIGNEE(S) CLEAN POWER RESEARCH, L.L.C. (Napa, California)
INVENTOR(S) Thomas E. Hoff (Napa, California)
ABSTRACT A system and method for determining seasonal energy consumption with the aid of a digital computer is provided. Through a power metering energy loads for a building situated in a known location are assessed as measured over a seasonal time period. Outdoor temperatures for the building are assessed as measured over the seasonal time period through a temperature monitoring infrastructure. A digital computer comprising a processor and a memory that is adapted to store program instructions for execution by the processor is operated, the program instructions capable of: expressing each energy load as a function of the outdoor temperature measured at the same time of the seasonal time period in point-intercept form; and taking a slope of the point-intercept form as the fuel rate of energy consumption during the seasonal time period.
FILED Monday, September 28, 2020
APPL NO 17/035134
ART UNIT 2896 — Optics
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/40 (20130101)

Meteorology
G01W 1/12 (20130101)

Electric Digital Data Processing
G06F 30/00 (20200101)
G06F 30/20 (20200101)
G06F 2119/06 (20200101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/02 (20130101)
G06Q 10/04 (20130101)
G06Q 50/06 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 3/383 (20130101)
H02J 2203/20 (20200101)

Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules
H02S 50/00 (20130101)
H02S 50/10 (20141201) Original (OR) Class

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/56 (20130101)
Y02E 60/00 (20130101)

Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids
Y04S 10/50 (20130101)
Y04S 40/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 11471528 Sitkovsky et al.
FUNDED BY
APPLICANT(S) The Government of the United States of America as represented by the Secretary of the Department (Bethesda, Maryland)
ASSIGNEE(S) The Government of the United States of America as represented by the Secretary of the Department (, None)
INVENTOR(S) Michail V. Sitkovsky (Boston, Massachusetts);  Akio Ohta (Newton, Massachusetts)
ABSTRACT A method is provided herein to increase an immune response to an antigen. The method includes administering an agent that inhibits extracellular adenosine or inhibits adenosine receptors. Also disclosed are methods to increase the efficacy of a vaccine and to increase an immune response to a tumor antigen or immune cell-mediated tumor destruction.
FILED Tuesday, April 23, 2019
APPL NO 16/391423
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/00 (20130101)
A61K 31/52 (20130101)
A61K 31/53 (20130101)
A61K 31/365 (20130101)
A61K 31/519 (20130101)
A61K 31/522 (20130101)
A61K 31/7088 (20130101)
A61K 35/17 (20130101)
A61K 39/0011 (20130101)
A61K 39/39 (20130101) Original (OR) Class
A61K 39/39558 (20130101)
A61K 45/06 (20130101)
A61K 2039/55561 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5041 (20130101)
G01N 33/5055 (20130101)
G01N 2333/705 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11474175 Bulatowicz
FUNDED BY
APPLICANT(S) Michael D. Bulatowicz (Sun Prairie, Wisconsin)
ASSIGNEE(S) NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia)
INVENTOR(S) Michael D. Bulatowicz (Sun Prairie, Wisconsin)
ABSTRACT A heater system includes a current source configured to generate an input current and to receive a return current. The system also includes a heater configured to generate heat in response to the input current. The system further includes a plurality of current lead wires interconnecting the current source and the heater and being configured to provide the input current to the heater and to conduct the return current from the heater. Each of the plurality of current lead wires is arranged on a separate substrate layer such that each of the plurality of current lead wires are each spaced apart from each other. At least one of the input current and the return current is divided to be conducted on two or more of the plurality of current lead wires.
FILED Monday, January 13, 2020
APPL NO 16/741302
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/26 (20130101)
G01R 33/3804 (20130101) Original (OR) Class

Electric Heating; Electric Lighting Not Otherwise Provided for
H05B 3/03 (20130101)
H05B 3/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11476876 Lavery et al.
FUNDED BY
APPLICANT(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
ASSIGNEE(S) BAE Systems Information and Electronic System Integration Inc. (Nashua, New Hampshire)
INVENTOR(S) Richard J. Lavery (Huntington, New York);  Peter Ladubec, Jr. (Centereach, New York)
ABSTRACT Techniques are provided for the generation of a calibration signal for use on an analog to digital converter (ADC). A system implementing the techniques according to an embodiment includes a calibration signal generator configured to generate a calibration tone, located in a first frequency band, in response to a calibration enable signal. The system also includes a signal summing circuit configured to generate an ADC input signal as a sum of a received signal and the calibration tone. The received signal is located in a second frequency band. The system further includes an ADC circuit configured to convert the ADC input signal to a baseband digital output signal and to perform self-calibration, based on the calibration tone, in response to the calibration enable signal. The frequency bands and the amplitude of the calibration tone are chosen to reduce interference between the received signal and the calibration tone.
FILED Tuesday, December 07, 2021
APPL NO 17/544210
ART UNIT 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Transmission
H04B 1/0032 (20130101) Original (OR) Class
H04B 1/1676 (20130101)
H04B 17/11 (20150115)
H04B 17/21 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11476912 Robinson
FUNDED BY
APPLICANT(S) Rampart Communications, Inc. (Annapolis, Maryland)
ASSIGNEE(S) RAMPART COMMUNICATIONS, INC. (Annapolis, Maryland)
INVENTOR(S) Matthew Brandon Robinson (Crownsville, Maryland)
ABSTRACT A processor coupled to a first communication device produces and transmits a first encoded vector and a second encoded vector to a second communication device via a communication channel that applies a channel transformation to the encoded vectors during transmission. A processor coupled to the second communication device receives the transformed signals, constructs a matrix based on the transformed signals, detects an effective channel thereof, and identifies left and right singular vectors of the effective channel. A precoding matrix is selected from a codebook of unitary matrices based on a message, and a second encoded vector is produced based on a second known vector, the precoding matrix, a complex conjugate of the left singular vectors, and the right singular vectors. A first symbol of the second encoded vector and a second symbol of the second encoded vector are sent to the first communication device for identification of the message.
FILED Friday, September 17, 2021
APPL NO 17/478099
ART UNIT 2637 — Optical Communications
CURRENT CPC
Transmission
H04B 7/0417 (20130101)
H04B 7/0456 (20130101)
H04B 7/0634 (20130101) Original (OR) Class
H04B 7/0639 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, October 18, 2022.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20221018.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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