FedInvent™ Patents

Patent Details for Tuesday, November 22, 2022 

This page was updated on Wednesday, November 23, 2022 at 12:43 PM GMT

Department of Health and Human Services (HHS) 

US 11503819 Taylor et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Sanaria Inc. (Rockville, Maryland);  The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) Sanaria Inc. (Rockville, Maryland);  The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Russell H. Taylor (Severna Park, Maryland);  Gregory Chirikjian (Towson, Maryland);  Iulian Iordachita (Lutherville, Maryland);  Henry Phalen (Baltimore, Maryland);  Hongtao Wu (Baltimore, Maryland);  Mengdi Xu (Pittsburgh, Pennsylvania);  Shengnan Lu (Beijing, China PRC);  Michael Aaron Pozin (Lincolnshire, Illinois);  Jin Seob Kim (Ellicott City, Maryland);  Can Kocabalkanli (Baltimore, Maryland);  Balazs Vagvolgyi (Baltimore, Maryland);  Brian K. Chirikjian (Towson, Maryland);  Joshua Davis (Columbus, Ohio);  Ting Da (Xi'an, China PRC);  John S. Chirikjian (Towson, Maryland);  Sumana Chakravarty (Derwood, Maryland);  Stephen Hoffman (Gaithersburg, Maryland)
ABSTRACT Systems and methods for providing a combined mosquito staging and dissection system are disclosed. The system can include a mosquito staging subsystem; a robotic pick-and-place station; and a dissection, extrusion, collection, and disposal subsystem. The subsystems can include one or more stations to provide orientation, decapitation, extrusion of salivary glands, and disposal of carcasses of the mosquitoes. The resident live sporozoites from the salivary glands can be used to produce Plasmodium SPZ-based vaccines.
FILED Monday, August 17, 2020
APPL NO 16/995164
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Catching, Trapping or Scaring of Animals; Apparatus for the Destruction of Noxious Animals or Noxious Plants
A01M 1/026 (20130101) Original (OR) Class
A01M 2200/011 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504011 Jain et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Vignet Incorporated (Fairfax, Virginia)
ASSIGNEE(S) VigNet Incorporated (Fairfax, Virginia)
INVENTOR(S) Praduman Jain (Fairfax, Virginia);  Josh Schilling (Salem, Oregon);  Dave Klein (Oakton, Virginia)
ABSTRACT Methods, systems, and apparatus, including computer programs encoded on computer-storage media, for geofencing and location tracking for predicting and limiting disease exposure. In some implementations, location tracking data is received indicating locations of user devices over time. Location tags specifying visits of the user devices to different locations indicated by the location tracking data are defined. A geofence is assigned to each of the location tags to specify a geofenced area corresponding to the location tag. Disease transmission scores are assigned to first location tags representing visits of a first user. A disease exposure score is determined for a second user whose user device is determined, based on the location tracking data, to have entered at least one of the geofenced areas corresponding to the first location tags.
FILED Wednesday, August 05, 2020
APPL NO 16/985616
ART UNIT 3626 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/021 (20130101)
A61B 5/0022 (20130101)
A61B 5/024 (20130101)
A61B 5/486 (20130101)
A61B 5/0816 (20130101)
A61B 5/1112 (20130101)
A61B 5/1118 (20130101)
A61B 5/02055 (20130101) Original (OR) Class
A61B 5/4839 (20130101)
A61B 5/7264 (20130101)
A61B 5/7275 (20130101)
A61B 5/14532 (20130101)
A61B 5/14551 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 1/68 (20130101)
G01S 19/51 (20130101)

Computer Systems Based on Specific Computational Models
G06N 5/04 (20130101)
G06N 20/00 (20190101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 10/60 (20180101)
G16H 20/10 (20180101)
G16H 40/20 (20180101)
G16H 40/67 (20180101)
G16H 50/20 (20180101)
G16H 50/30 (20180101)
G16H 50/80 (20180101)
G16H 70/20 (20180101)

Wireless Communication Networks
H04W 4/029 (20180201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504035 Kintz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Profusa, Inc. (South San Francisco, California)
ASSIGNEE(S) Profusa, Inc. (Emeryville, California)
INVENTOR(S) Gregory J. Kintz (Santa Cruz, California);  William A. McMillan (La Honda, California);  Natalie A. Wisniewski (San Francisco, California)
ABSTRACT Some embodiments described herein relate to an apparatus including a light source configured to transmit an excitation optical signal to an implanted sensor and a detector configured to detect an analyte-dependent optical signal emitted from an implanted sensor. The apparatus can include a lens configured to focus at least a portion of the analyte-dependent optical signal onto the detector.
FILED Monday, March 04, 2019
APPL NO 16/291268
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0017 (20130101)
A61B 5/1459 (20130101) Original (OR) Class
A61B 5/14532 (20130101)
A61B 2562/043 (20130101)
A61B 2562/0233 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504077 Bambot et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Shabbir Bambot (West Hills, California);  Joesph Webster Stayman (Baltimore, Maryland);  Andrew Leong (Baltimore, Maryland)
ASSIGNEE(S)
INVENTOR(S) Shabbir Bambot (West Hills, California);  Joesph Webster Stayman (Baltimore, Maryland);  Andrew Leong (Baltimore, Maryland)
ABSTRACT A method is provided to perform an imaging scan on a target tissue. The imaging scan includes generating a signal directed at a portion of a target tissue using a collimator that includes a slot, wherein a source of a signal assembly is incoherently interrupted. The method also includes receiving at least a portion of the signal from the portion of the target tissue at a linear signal detector positioned directly opposite from the signal assembly with respect to the target tissue, and simultaneously translating the linear signal detector and adjusting a width of the at least one slot of the collimator such that a fan width of the signal at the linear signal detector corresponds to a width of a detector window disposed in the linear signal detector. The method also includes rotating a stage about the target tissue, and repeating performing the imaging scan on the target tissue.
FILED Tuesday, February 16, 2021
APPL NO 17/176593
ART UNIT 2884 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/06 (20130101) Original (OR) Class
A61B 6/032 (20130101)
A61B 6/54 (20130101)
A61B 6/502 (20130101)
A61B 6/4078 (20130101)
A61B 6/4452 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504095 Mauldin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Rivanna Medical LLC (Charlottesville, Virginia)
ASSIGNEE(S) Rivanna Medical, Inc. (Charlottesville, Virginia)
INVENTOR(S) Frank William Mauldin (Charlottesville, Virginia);  Adam Dixon (Charlottesville, Virginia);  Kevin Owen (Crozet, Virginia)
ABSTRACT The position and orientation of an ultrasound probe is tracked in three dimensions to provide highly-accurate three-dimensional bone surface images that can be used for anatomical assessment and/or procedure guidance. The position and orientation of a therapy applicator can be tracked in three dimensions to provide feedback to align the projected path of the therapy applicator with a desired path for the therapy applicator or to provide feedback to align the potential therapy field of a therapy applicator with a target anatomical site. The three-dimensional bone surface images can be fit to a three-dimensional model of the anatomical site to provide or display additional information to the user to improve the accuracy of the anatomical assessment and/or procedure guidance.
FILED Tuesday, January 08, 2019
APPL NO 16/963117
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 8/13 (20130101)
A61B 8/466 (20130101)
A61B 8/483 (20130101) Original (OR) Class
A61B 8/0841 (20130101)
A61B 8/0875 (20130101)
A61B 8/4263 (20130101)
A61B 8/5207 (20130101)
A61B 2562/0257 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 7/00 (20130101)
A61N 2007/0004 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504154 Wood et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Bradford Wood (Potomac, Maryland);  Sheng Xu (Rockville, Maryland);  Reza Seifabadi (Bethesda, Maryland)
ABSTRACT Prostate biopsy systems are provided that include a 3D ultrasound probe support configured to receive an ultrasound probe for transperineal imaging. One or more template grids can have a plurality of apertures extending therethrough to receive and guide a biopsy needle along a trajectory associated with respective apertures when the template grid is fixed to the support and the biopsy system is positioned in the perineal area of a patient. Patient-specific template grids can also be developed and produced. This system enables fully transperineal prostate biopsy (i.e. both imaging and needle placement are perineal) and eliminates the need for an external racking device for image fusion as well as needle tracking. In addition, it reduces the infection risk associated to transrectal approach.
FILED Friday, July 28, 2017
APPL NO 16/320980
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 8/463 (20130101)
A61B 8/466 (20130101)
A61B 8/483 (20130101)
A61B 8/0841 (20130101)
A61B 8/4209 (20130101)
A61B 8/5261 (20130101)
A61B 10/0241 (20130101)
A61B 17/3403 (20130101) Original (OR) Class
A61B 90/11 (20160201)
A61B 2017/3411 (20130101)
A61B 2017/3413 (20130101)
A61B 2034/105 (20160201)
A61B 2034/107 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504303 Yelick et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts);  THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Cambridge, Massachusetts)
ASSIGNEE(S) TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts);  THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Cambridge, Massachusetts)
INVENTOR(S) Pamela C. Yelick (Boston, Massachusetts);  Ali Khademhosseini (Cambridge, Massachusetts)
ABSTRACT A dental tissue regenerative composition. The composition includes a combination of (1) human dental pulp stem cells and (2) at least one of human umbilical vein endothelial cells or vascular endothelial growth factor. The combination is encapsulated in a light-activated gelatin methacrylate hydrogel.
FILED Tuesday, December 21, 2021
APPL NO 17/557483
ART UNIT 1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Dentistry; Apparatus or Methods for Oral or Dental Hygiene
A61C 5/40 (20170201)

Preparations for Medical, Dental, or Toilet Purposes
A61K 6/56 (20200101)
A61K 6/62 (20200101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504325 Polt et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
INVENTOR(S) Robin L. Polt (Tucson, Arizona);  Dillon Hanrahan (Tucson, Arizona);  Lajos Z. Szabo (Tucson, Arizona);  Michael L. Heien (Tucson, Arizona);  Chenxi Liu (Tucson, Arizona)
ABSTRACT Methods for quality control and optimizing the formation and characterization of micelles, vesicles or other aggregates are described herein. Pharmaceutically relevant peptides may be modified to form glycopeptide surfactants which form micelles or other aggregates with another surfactant. Glycopeptide and glycolipid surfactants can aggregate to form particles that enhance drug delivery. The glycopeptide surfactants may be drugs or pro-drugs which are delivered via the micelles or other aggregated structures.
FILED Thursday, August 09, 2018
APPL NO 16/637671
ART UNIT 1699 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/107 (20130101) Original (OR) Class
A61K 38/018 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504329 Mathiowitz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Brown University (Providence, Rhode Island);  TherapyX, Inc. (Buffalo, New York)
ASSIGNEE(S) BROWN UNIVERSITY (Providence, Rhode Island);  THEBAPYX, INC. (Buffalo, New York)
INVENTOR(S) Edith Mathiowitz (Brookline, Massachusetts);  Stacia Furtado (Pawcatuck, Connecticut);  Nejat Egilmez (Louisville, Kentucky);  Thomas Conway (Hamburg, New York)
ABSTRACT Compositions for stabilizing and delivering proteins and/or other bioactive agents are disclosed. The bioactive agents are embedded or encapsulated in a crystalline matrix. Typically the bioactive agents are in the form of micro- or nanoparticles. The crystalline matrix confers enhanced stability to the agents embedded therein relative to other microparticulate or nanoparticulate bioactive agents. The carriers are especially useful for stabilizing bioactive macromolecules, such as proteins.
FILED Tuesday, June 23, 2020
APPL NO 16/909493
ART UNIT 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/14 (20130101) Original (OR) Class
A61K 9/19 (20130101)
A61K 9/1635 (20130101)
A61K 9/1641 (20130101)
A61K 9/1647 (20130101)
A61K 9/2004 (20130101)
A61K 38/17 (20130101)
A61K 38/20 (20130101)
A61K 38/28 (20130101)
A61K 38/191 (20130101)
A61K 38/193 (20130101)
A61K 38/208 (20130101)
A61K 38/1841 (20130101)
A61K 38/1858 (20130101)
A61K 38/1866 (20130101)
A61K 38/2066 (20130101)
A61K 39/00 (20130101)
A61K 2039/555 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504335 Gottipati et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) University of Kentucky Research Foundation (Lexington, Kentucky)
ASSIGNEE(S) University of Kentucky Research Foundation (Lexington, Kentucky)
INVENTOR(S) Anuhya Gottipati (Lexington, Kentucky);  Irina Kalashnikova (Lexington, Kentucky);  Ahmed Abdel-Latif (Lexington, Kentucky);  Bradley J. Berron (Lexington, Kentucky)
ABSTRACT The presently-disclosed subject matter relates to compositions of dual layer encapsulated cells, dual layer encapsulated stem cells. The presently-disclosed subject matter further relates to methods for improving retention of cells in vivo at a site of injury.
FILED Tuesday, June 18, 2019
APPL NO 16/445046
ART UNIT 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/4825 (20130101) Original (OR) Class
A61K 35/28 (20130101)
A61K 35/44 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/10 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504338 Reinhard et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts)
ASSIGNEE(S) TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts)
INVENTOR(S) Bjoern Markus Reinhard (Brookline, Massachusetts);  Suryaram Gummuluru (Westwood, Massachusetts)
ABSTRACT Embodiments disclosed herein relates to ganglioside GM3-containing mixed lipids nanoparticles having an overall size between 60-100 nm, the making thereof and the uses. The nanoparticles selectively targeted to CD169+ expressing cells such as dendritic cells and macrophage. The nanoparticles are endocytosed by the CD169+ expressing cells.
FILED Thursday, April 09, 2020
APPL NO 16/844526
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/127 (20130101)
A61K 9/1271 (20130101)
A61K 9/1272 (20130101)
A61K 9/5115 (20130101)
A61K 9/5123 (20130101) Original (OR) Class
A61K 9/5192 (20130101)
A61K 47/61 (20170801)
A61K 47/543 (20170801)
A61K 47/6911 (20170801)
A61K 47/6923 (20170801)
A61K 47/6929 (20170801)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504346 Tomat et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
INVENTOR(S) Elisa Tomat (Tucson, Arizona);  Tsuhen Chang (Tucson, Arizona);  Eman A. Akam (Tucson, Arizona)
ABSTRACT Compositions of pro-chelator compounds are described herein. The pro-chelators may be activated in reducing conditions, such as in the intracellular space, so as to sequester metals such as iron. The pro-chelators may be used to target malignant cells or in the treatment in a condition associated with metal ion disregulation.
FILED Monday, November 26, 2018
APPL NO 16/200286
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/175 (20130101) Original (OR) Class

Acyclic or Carbocyclic Compounds
C07C 337/04 (20130101)

Heterocyclic Compounds
C07D 249/08 (20130101)
C07D 277/36 (20130101)
C07D 307/64 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504359 Panicker et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) ANGION BIOMEDICA CORP. (Uniondale, New York)
ASSIGNEE(S) Angion Biomedica Corp. (Uniondale, New York)
INVENTOR(S) Bijoy Panicker (Holbrook, New York);  Rama K. Mishra (Chicago, Illinois);  Dong Sung Lim (Fair Lawn, New Jersey);  Lambertus J. W. M. Oehlen (Westbury, New York);  Dawoon Jung (Tenafly, New Jersey)
ABSTRACT The present invention provides compounds having the general structural formula (I)
and pharmaceutically acceptable derivatives thereof, as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases involving abnormal or excessive fibrosis.
FILED Friday, August 02, 2019
APPL NO 16/530688
ART UNIT 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/437 (20130101) Original (OR) Class
A61K 31/496 (20130101)
A61K 31/4353 (20130101)
A61K 31/5377 (20130101)

Heterocyclic Compounds
C07D 401/02 (20130101)
C07D 401/14 (20130101)
C07D 471/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504360 Pahan
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Rush University Medical Center (Chicago, Illinois)
ASSIGNEE(S) Rush University Medical Center (Chicago, Illinois)
INVENTOR(S) Kalipada Pahan (Skokie, Illinois)
ABSTRACT The present invention generally relates to compositions and methods for treating a neurological disorder in a subject, the method including administering to the subject in need of such treatment a composition including a therapeutically effective amount of a CCR5 antagonist. The CCR5 antagonist may be, for example, maraviroc. The neurological disorder may be, for example, Alzheimer's disease, Parkinson's disease, dementia with Lewy bodies or multiple system atrophy.
FILED Friday, December 28, 2018
APPL NO 16/958903
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/0053 (20130101)
A61K 31/439 (20130101) Original (OR) Class
A61K 31/499 (20130101)
A61K 31/506 (20130101)
A61K 31/4178 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/16 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504369 Kennedy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) President and Trustees of Bates College (Lewiston, Maine)
ASSIGNEE(S) President and Trustees of Bates College (Lewiston, Maine)
INVENTOR(S) Andrew Kennedy (Lewiston, Maine);  Gabriella N. L. Chua (San Francisco, California);  Kelly L. Wassarman (Brighton, Massachusetts);  Haoyu Sun (Beijing, China PRC)
ABSTRACT Provided herein, in some embodiments, are cytosine analogs, compositions comprising cytosine analogs, and methods of use for inhibiting a Ten-eleven translocation (TET) enzyme.
FILED Friday, March 20, 2020
APPL NO 16/825324
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/513 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504373 Bennett et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) YALE UNIVERSITY (New Haven, Connecticut)
ASSIGNEE(S) YALE UNIVERSITY (New Haven, Connecticut)
INVENTOR(S) Anton Bennett (Wilton, Connecticut);  Jonathan Ellman (Guilford, Connecticut);  Haya Jamali (New Haven, Connecticut);  Karen S. Anderson (Guilford, Connecticut);  Elias Lolis (Fairfield, Connecticut);  Denton Hoyer (West Haven, Connecticut)
ABSTRACT The present invention provides compounds and methods for treating, ameliorating, and/or preventing a MKP-5 modulated disease. In certain embodiments, the MKP-5 modulated disease is a fibrotic disease.
FILED Tuesday, December 18, 2018
APPL NO 16/954514
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/517 (20130101)
A61K 31/519 (20130101) Original (OR) Class

Heterocyclic Compounds
C07D 239/78 (20130101)
C07D 471/04 (20130101)
C07D 491/052 (20130101)
C07D 495/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504394 Chang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Christopher J. Chang (Berkeley, California);  Timothy Su (Berkeley, California);  Marie Heffern (Berkeley, California)
ABSTRACT The present disclosure provides ionophore compounds, which are useful for facilitating delivery of a metal ion to a cell, tissue or organ of interest. The present disclosure provides compositions comprising the subject ionophore compounds. The present disclosure provides methods of delivering a metal ion intracellularly to a target cell. The present disclosure also provides methods of treating a condition associated with a metal deficiency in an individual.
FILED Monday, October 07, 2019
APPL NO 16/594798
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 33/34 (20130101) Original (OR) Class
A61K 45/06 (20130101)
A61K 47/60 (20170801)
A61K 47/64 (20170801)
A61K 47/545 (20170801)
A61K 47/549 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 1/16 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504397 Bam et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina)
ASSIGNEE(S) University of South Carolina (Columbia, South Carolina)
INVENTOR(S) Marpe Bam (Columbia, South Carolina);  Prakash Nagarkatti (Columbia, South Carolina);  Mitzi Nagarkatti (Columbia, South Carolina)
ABSTRACT The present disclosure is directed to compositions and methods to treat the inflammatory response present in certain diseases and illnesses by modifying a dysregulation of one or more genes associated with the Wnt/β-catenin signaling pathway. Embodiments of the disclosure can provide methods for treating an inflammatory response in a patient by identifying the inflammatory response and modifying the inflammatory response.
FILED Wednesday, December 04, 2019
APPL NO 16/703329
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/4709 (20130101)
A61K 35/17 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/00 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1138 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504414 Xie et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Center for Research Resources (NCRR)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) Meharry Medical College (Nashville, Tennessee)
ASSIGNEE(S)
INVENTOR(S) Hua Xie (Nashville, Tennessee);  Richard J. Lamont (Louisville, Kentucky)
ABSTRACT Peptides related to certain portions of the arginine deiminase enzyme from the bacterium Streptococcus cristatus are provided that disrupt the formation and composition of biofilms containing the oral pathogen Porphyromonas gingivalis, and also modulate the virulence of P. gingivalis. Pharmaceutical compositions containing such peptides and method of using the same are disclosed.
FILED Monday, March 25, 2019
APPL NO 16/363908
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0053 (20130101)
A61K 38/00 (20130101)
A61K 38/164 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)

Peptides
C07K 14/315 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/78 (20130101)
C12N 15/52 (20130101)

Enzymes
C12Y 305/03006 (20130101)
C12Y 305/03015 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504423 Balint et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Etubics Corporation (Seattle, Washington)
ASSIGNEE(S) Etubics Corporation (Seattle, Washington)
INVENTOR(S) Joseph P. Balint (Seattle, Washington);  Frank R. Jones (Seattle, Washington);  Richard B. Gayle, III (Seattle, Washington)
ABSTRACT Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided.
FILED Wednesday, April 27, 2022
APPL NO 17/731106
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/191 (20130101)
A61K 38/193 (20130101)
A61K 38/204 (20130101)
A61K 38/208 (20130101)
A61K 38/217 (20130101)
A61K 38/2013 (20130101)
A61K 38/2026 (20130101)
A61K 38/2033 (20130101)
A61K 38/2046 (20130101)
A61K 38/2066 (20130101)
A61K 39/00 (20130101)
A61K 39/0011 (20130101)
A61K 39/12 (20130101) Original (OR) Class
A61K 39/21 (20130101)
A61K 39/235 (20130101)
A61K 39/001106 (20180801)
A61K 39/001182 (20180801)
A61K 2039/54 (20130101)
A61K 2039/57 (20130101)
A61K 2039/545 (20130101)
A61K 2039/575 (20130101)
A61K 2039/5256 (20130101)
A61K 2039/55555 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/005 (20130101)
C07K 14/71 (20130101)
C07K 14/70503 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
C12N 2710/10034 (20130101)
C12N 2710/10321 (20130101)
C12N 2710/10334 (20130101)
C12N 2710/10343 (20130101)
C12N 2710/10371 (20130101)
C12N 2710/20034 (20130101)
C12N 2740/15034 (20130101)
C12N 2740/16234 (20130101)
C12N 2800/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504427 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Yingxiao Wang (La Jolla, California);  Shu Chien (La Jolla, California);  Yijia Pan (La Jolla, California);  Yiqian Wu (La Jolla, California);  Shaoying Lu (La Jolla, California);  Kirk Shung (La Jolla, California)
ABSTRACT In alternative embodiments, provided are compositions, including products of manufacture and kits, and methods, for remotely-controlled and non-invasive manipulation of intracellular nucleic acid expression, genetic processes, function and activity in live cells, e.g., adding functions or changing or adding specificities for immune cells, for monitoring physiologic processes, for the correction of pathological processes and for control of therapeutic outcomes. In alternative embodiments, provided are ultrasound-based thermal or mechanical stimulations, and thermo- or mechano-sensitive protein, either synthetically engineered or natively (endogenously) occurring, integrated to control the production of intracellular nucleic acid and gene expression, e.g., for the expression of biological-active proteins, which can be used, in alternative embodiments, for diagnostic or therapeutic purposes. In alternative embodiments, exemplary thermo- and mechanogenetic systems provided herein allow a deep penetration of stimulation and manipulation in vivo at centimeter-level depth with high spatiotemporal precision.
FILED Wednesday, November 22, 2017
APPL NO 16/463316
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 41/0028 (20130101)
A61K 41/0033 (20130101) Original (OR) Class

Peptides
C07K 16/2803 (20130101)
C07K 2317/569 (20130101)
C07K 2317/622 (20130101)
C07K 2319/03 (20130101)
C07K 2319/33 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504431 Prausnitz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Emory University (Atlanta, Georgia);  Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Emory University (Atlanta, Georgia);  Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Mark R. Prausnitz (Atlanta, Georgia);  Bryce Chiang (Atlanta, Georgia)
ABSTRACT Provided herein are fluid formulations for administration to a suprachoroidal space of an eye of a patient. The fluid formulations may include a pharmaceutical agent, a binding molecule, or a combination thereof. The pharmaceutical agent and the binding molecule may be bonded to each other covalently, non-covalently, or a combination thereof. The pharmaceutical agent may be configured to bond to an ocular tissue. The binding molecule may be configured to bond to an ocular tissue. Methods of administering the fluid formulations, methods of expanding a suprachoroidal space, and methods of reducing the minimum force to separate the sclera and choroid are provided.
FILED Thursday, July 20, 2017
APPL NO 16/318804
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/06 (20130101)
A61K 9/08 (20130101)
A61K 9/0021 (20130101)
A61K 9/0048 (20130101)
A61K 47/10 (20130101)
A61K 47/38 (20130101) Original (OR) Class

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 5/31531 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 27/02 (20180101)

Peptides
C07K 16/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504434 Yang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania)
ASSIGNEE(S) The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S) Jian Yang (State College, Pennsylvania);  Cheng Dong (State College, Pennsylvania);  Zhiwei Xie (State College, Pennsylvania)
ABSTRACT In one aspect, methods of targeted nanoparticles and cell delivery are described herein. In some embodiments methods described herein comprise coupling nanoparticles and cells to a carrier cell to form a nanoparticle-cell conjugate or cell-cell conjugate, disposing the nanoparticle-cell or cell-cell conjugate in a biological environment, and delivering the nanoparticles and cells to target cells or tissues located within the biological environment. The nanoparticles comprise a biodegradable photoluminescent polymer, and the nanoparticle-cell conjugate is formed using one or more click chemistry reaction products.
FILED Monday, January 06, 2020
APPL NO 16/734816
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5153 (20130101)
A61K 31/337 (20130101)
A61K 31/437 (20130101)
A61K 47/62 (20170801)
A61K 47/65 (20170801)
A61K 47/593 (20170801)
A61K 47/6901 (20170801) Original (OR) Class
A61K 47/6937 (20170801)
A61K 49/0093 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504437 Halas et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) William Marsh Rice University (Houston, Texas)
ASSIGNEE(S) WILLIAM MARSH RICE UNIVERSITY (Houston, Texas);  BAYLOR COLLEGE OF MEDICINE (Houston, Texas)
INVENTOR(S) Nancy J. Halas (Houston, Texas);  Ciceron Ayala-Orozco (Stafford, Texas);  Sandra Bishnoi (Houston, Texas);  Luke Henderson (Houston, Texas);  Oara Neumann (Houston, Texas);  Robia Pautler (Houston, Texas);  Peter Nordlander (Houston, Texas)
ABSTRACT A Magnetic Resonance Imaging (MRI) enhancement agent includes a plurality of particles, each particle including: a metal core; a dielectric shell disposed on the metal core comprising at least one MRI contrast agent; and a metal shell disposed on the exterior surface of the dielectric shell that encapsulates the dielectric shell.
FILED Friday, September 15, 2017
APPL NO 15/706429
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/1833 (20130101)
A61K 49/1881 (20130101) Original (OR) Class

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 18/31 (20130101)
C23C 18/1646 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 3/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504438 Lakshmanan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Anupama Lakshmanan (Pasadena, California);  Arash Farhadi (Pasadena, California);  Suchita P. Nety (Sunnyvale, California);  Raymond W. Bourdeau (Watertown, Massachusetts);  Mikhail Shapiro (Los Angeles, California)
ABSTRACT Gas vesicles, protein variants and related compositions methods and systems for singleplexed and/or multiplexed ultrasound imaging of a target site in which a gas vesicle provides contrast for the imaging which is modifiable by application of a selectable acoustic collapse pressure value of the gas vesicle.
FILED Thursday, October 17, 2019
APPL NO 16/656417
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 8/481 (20130101)
A61B 8/5238 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 49/0002 (20130101)
A61K 49/0045 (20130101)
A61K 49/0093 (20130101)
A61K 49/221 (20130101)
A61K 49/223 (20130101) Original (OR) Class

Peptides
C07K 14/195 (20130101)
C07K 2319/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504490 Tarler
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Cleveland Medical Devices Inc. (Cleveland, Ohio)
ASSIGNEE(S) Cleveland Medical Devices Inc. (Cleveland, Ohio)
INVENTOR(S) Matthew D. Tarler (Avon, Ohio)
ABSTRACT The present invention pertains to a system, method, and device for treating sleep disorders. The present invention is particularly useful in the delivery of carbon dioxide (CO2) to a subject and in the treatment of sleep apnea. Furthermore, integration of components with various sensors and apparatuses associated therewith and attached thereto preferably complete a rebreathing circuit in the present invention. In various embodiments of the present invention where the above components are integrated as a rebreathing circuit, a subject is both the source and recipient of a controlled concentration of carbon dioxide. In such embodiments, treatment of sleep disorders becomes much more efficient and effective.
FILED Thursday, January 24, 2019
APPL NO 16/255889
ART UNIT 3619 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 16/06 (20130101)
A61M 16/10 (20130101)
A61M 16/12 (20130101)
A61M 16/0045 (20130101) Original (OR) Class
A61M 16/122 (20140204)
A61M 16/0883 (20140204)
A61M 2016/103 (20130101)
A61M 2202/0225 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504524 Giszter
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Drexel University (Philadelphia, Pennsylvania)
ASSIGNEE(S) Drexel University (Philadelphia, Pennsylvania)
INVENTOR(S) Simon Francis Giszter (Havertown, Pennsylvania)
ABSTRACT A multi-site probe for interfacing with the central nervous system includes one more structures disposed perpendicularly on a backing layer, where each structure includes a braided sleeve over a flexible or rigid core, and a delivery-vehicle. The structures may include optrodes and electrodes. The location of the probe may be determined through the application of combinatorics.
FILED Wednesday, September 14, 2016
APPL NO 15/759441
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/24 (20210101)
A61B 5/72 (20130101)
A61B 5/0084 (20130101)
A61B 5/291 (20210101)
A61B 5/4058 (20130101)
A61B 5/4064 (20130101)
A61B 5/6864 (20130101)
A61B 5/6868 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0529 (20130101) Original (OR) Class
A61N 1/0551 (20130101)
A61N 5/0601 (20130101)
A61N 5/0622 (20130101)
A61N 2005/063 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504527 Bhadra et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) Niloy Bhadra (Cleveland Heights, Ohio);  Kevin L. Kilgore (Avon Lake, Ohio);  Narendra Bhadra (Chesterland, Ohio);  Jesse Wainright (Willoughby Hills, Ohio);  Tina Vrabec (Willoughby Hills, Ohio);  Manfred Franke (South Euclid, Ohio)
ABSTRACT Devices and methods for blocking signal transmission through neural tissue. One step of a method includes placing a therapy delivery device into electrical communication with the neural tissue. The therapy delivery device includes an electrode contact having a high charge capacity material. A multi-phase direct current (DC) can be applied to the neural tissue without damaging the neural tissue. The multi-phase DC includes a cathodic DC phase and anodic DC phase that collectively produce a neural block and reduce the charge delivered by the therapy delivery device. The DC delivery can be combined with high frequency alternating current (HFAC) block to produce a system that provides effective, safe, long term block without inducing an onset response.
FILED Tuesday, September 10, 2019
APPL NO 16/565841
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/06 (20130101)
A61N 1/20 (20130101)
A61N 1/0556 (20130101) Original (OR) Class
A61N 1/36064 (20130101)
A61N 1/36067 (20130101)
A61N 1/36071 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505523 Kuo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) City of Hope (Duarte, California);  Taipei Medical University (Taipei, Taiwan);  Academia Sinica (Taipei, Taiwan)
ASSIGNEE(S) CITY OF HOPE (Duarte, California);  TAIPEI MEDICAL UNIVERSITY (Taipei, Taiwan);  ACADEMIA SINICA (Taipei, Taiwan)
INVENTOR(S) Ya-Huei Kuo (Duarte, California);  Wei-Jan Huang (Taipei, Taiwan);  Chung-I Chang (Taipei, Taiwan)
ABSTRACT Provided herein, inter alia, are compound and methods of treating cancer by inhibiting HDAC8.
FILED Tuesday, May 07, 2019
APPL NO 16/405581
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 259/06 (20130101) Original (OR) Class

Heterocyclic Compounds
C07D 209/08 (20130101)
C07D 209/18 (20130101)
C07D 213/56 (20130101)
C07D 213/74 (20130101)
C07D 215/14 (20130101)
C07D 217/16 (20130101)
C07D 217/20 (20130101)
C07D 307/91 (20130101)
C07D 317/60 (20130101)
C07D 333/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505528 Campbell et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Axial Therapeutics, Inc. (Woburn, Massachusetts)
ASSIGNEE(S) Axial Therapeutics, Inc. (Woburn, Massachusetts)
INVENTOR(S) Anthony Stewart Campbell (Framingham, Massachusetts);  Bridget Cole (Quincy, Massachusetts);  Alessandra Bartolozzi (Norwalk, Connecticut)
ABSTRACT The present disclosure provides compounds useful for the prevention of amyloid formation and the treatment of amyloid related disorders, including synucleopathies such as Parkinson's Disease.
FILED Monday, August 06, 2018
APPL NO 16/636511
ART UNIT 1699 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/0053 (20130101)

Heterocyclic Compounds
C07D 215/56 (20130101) Original (OR) Class
C07D 333/68 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505531 Suto et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) SOUTHERN RESEARCH INSTITUTE (Birmingham, Alabama);  UAB RESEARCH FOUNDATION (Birmingham, Alabama)
ASSIGNEE(S) UAB RESEARCH FOUNDATION (Birmingham, Alabama);  SOUTHERN RESEARCH INSTITUTE (Birmingham, Alabama)
INVENTOR(S) Mark J. Suto (Homewood, Alabama);  Vandana V. Gupta (Birmingham, Alabama);  Wei Zhang (Wilmington, Massachusetts);  Joanne Murphy-Ullrich (Birmingham, Alabama)
ABSTRACT The present disclosure is concerned with piperazine-2,5-diones that are capable of inhibiting TGF-β and methods of treating cancers such as, for example, multiple myeloma and a hematologic malignancy, and methods of treating fibrotic conditions using these compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
FILED Monday, August 05, 2019
APPL NO 17/265357
ART UNIT 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 19/04 (20180101)
A61P 35/04 (20180101)

Heterocyclic Compounds
C07D 241/08 (20130101)
C07D 241/52 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505533 Aron et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) MICROBIOTIX, INC. (Worcester, Massachusetts);  THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania)
ASSIGNEE(S) MICROBIOTIX, INC. (Worcester, Massachusetts);  THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania)
INVENTOR(S) Zachary D. Aron (Acton, Massachusetts);  Steven M. Kwasny (Blackstone, Massachusetts);  Matthew C. Torhan (Worcester, Massachusetts);  Jay P. Barbor (Worcester, Massachusetts);  Steven C. Cardinale (Hopedale, Massachusetts);  Michelle M. Butler (Auburn, Massachusetts);  Timothy J. Opperman (Arlington, Massachusetts);  Kenneth C. Keiler (Boalsburg, Pennsylvania)
ABSTRACT The present invention is related to the development of therapeutics and prophylactics for the treatment and/or prevention of bacterial infections in humans and other mammals. A new class of small molecules is disclosed that inhibits the bacterial trans-translation/ribosome rescue mechanism and thus blocks infection of host cells by bacteria. Also disclosed are methods of using the small molecule inhibitors in the treatment/prevention of bacterial infections.
FILED Tuesday, August 21, 2018
APPL NO 16/640642
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 43/82 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)

Heterocyclic Compounds
C07D 271/113 (20130101) Original (OR) Class
C07D 413/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505555 Mekonnen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) AGENEBIO, INC. (Baltimore, Maryland)
ASSIGNEE(S) AGENEBIO, INC. (Baltimore, Maryland)
INVENTOR(S) Belew Mekonnen (Gilbertsville, Pennsylvania);  John A. Butera (Clarksburg, New Jersey);  Jianxing Huang (Bethlehem, Pennsylvania);  Hemantbhai Patel (Piscataway, New Jersey)
ABSTRACT This invention relates to benzodiazepine derivatives, compositions comprising therapeutically effective amounts of those benzodiazepine derivatives and methods of using those derivatives or compositions in treating cognitive impairment associated with central nervous system (CNS) disorders. In particular, it relates to the use of a α5-containing GABAA receptor agonist (e.g., a α5-containing GABAA receptor positive allosteric modulator) as described herein in treating cognitive impairment associated with central nervous system (CNS) disorders in a subject in need or at risk thereof, including, without limitation, subjects having or at risk for age-related cognitive impairment, Mild Cognitive Impairment (MCI), amnestic MCI (aMCI), Age-Associated Memory Impairment (AAMI), Age Related Cognitive Decline (ARCD), dementia, Alzheimer's Disease (AD), prodromal AD, post traumatic stress disorder (PTSD), schizophrenia, bipolar disorder, amyotrophic lateral sclerosis (ALS), cancer-therapy-related cognitive impairment, mental retardation, Parkinson's disease (PD), autism spectrum disorders, fragile X disorder, Rett syndrome, compulsive behavior, and substance addiction. It also relates to the use of a α5-containing GABAA receptor agonist (e.g., a α5-containing GABAA receptor positive allosteric modulator) as described herein in treating brain cancers (including brain tumors, e.g., medulloblastomas), and cognitive impairment associated therewith.
FILED Wednesday, December 20, 2017
APPL NO 16/471237
ART UNIT 1699 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 45/06 (20130101)

Heterocyclic Compounds
C07D 487/14 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505559 Yang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland);  YALE UNIVERSITY (New Haven, Connecticut)
ASSIGNEE(S) THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES OFFICE OF TECHNOLOGY TRANSFER, NATIONAL INSTITUTES OF HEALTH (Bethesda, Maryland);  YALE UNIVERSITY (New Haven, Connecticut)
INVENTOR(S) Shyh Ming Yang (Doylestown, Pennsylvania);  David J. Maloney (Points of Rocks, Maryland);  Natalia Martinez (Rockville, Maryland);  Adam Yasgar (Washington, District of Columbia);  Anton Simeonov (Bethesda, Maryland);  Vasilis Vasiliou (Guilford, Connecticut)
ABSTRACT The disclosure provides compounds of Formula I, which may be useful as aldehyde dehydrogenase inhibitors and the pharmaceutically acceptable salts thereof. The variables, J, R4, G, Q, and ring A are defined herein. Aldehyde dehydrogenase inhibitors of Formula I are useful for treating a variety of conditions including cancer and inflammation. The disclosure includes methods for using compounds and salts of Formula I to treat colon cancer, pancreatic cancer, nasopharyngeal carcinoma, thyroid cancer, prostate cancer, ovarian cancer, head and neck squamous cell carcinoma, lung cancer, hepatocellular carcinoma, leukemia, brain tumors breast cancer, atherosclerosis, ischaemic heart disease, acne vulgaris, asthma, autoimmune diseases, autoinflammatory diseases, chronic prostatitis, glomerulonephritis, inflammatory bowel disease, pelvic inflammatory disease, reperfusion injury, rheumatoid arthritis, sarcoidosis, transplant rejection, vasculitis, and interstitial cystitis. The disclosure also includes pharmaceutical compositions containing a compound or salt of Formula I.
FILED Tuesday, October 30, 2018
APPL NO 16/760345
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 215/54 (20130101)
C07D 401/04 (20130101)
C07D 401/06 (20130101)
C07D 401/12 (20130101)
C07D 401/14 (20130101)
C07D 409/14 (20130101)
C07D 413/04 (20130101)
C07D 471/04 (20130101)
C07D 491/107 (20130101)
C07D 491/113 (20130101) Original (OR) Class
C07D 495/04 (20130101)
C07D 495/10 (20130101)
C07D 519/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505560 Nowak et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts)
ASSIGNEE(S) DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts)
INVENTOR(S) Radoslaw P. Nowak (Boston, Massachusetts);  Eric S. Fischer (Newton, Massachusetts);  Nathanael S. Gray (Boston, Massachusetts);  Tinghu Zhang (Brookline, Massachusetts);  Zhixiang He (Brookline, Massachusetts);  Brian Groendyke (Chestnut Hill, Massachusetts)
ABSTRACT Disclosed are heterobifunctional compounds that effectuate selective degradation of a target protein, and which include a targeting ligand that binds a target protein and at least one other protein, a ligand that binds an E3 ubiquitin ligase or a component of E3 ubiquitin ligase, and a specificity modulating linker that links the first ligand and the second ligand. Pharmaceutical compositions containing the compounds, and methods of using and making the compounds are also disclosed.
FILED Friday, October 19, 2018
APPL NO 16/755502
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/55 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Heterocyclic Compounds
C07D 211/56 (20130101)
C07D 401/04 (20130101)
C07D 401/12 (20130101)
C07D 487/04 (20130101)
C07D 495/14 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505568 Niu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Trustees of Boston College (Chestnut Hill, Massachusetts)
ASSIGNEE(S) The Trustees of Boston College (Chesnut Hill, Massachusetts)
INVENTOR(S) Jia Niu (Lexington, Massachusetts);  Chao Liu (Newton, Massachusetts);  Cangjie Yang (Brighton, Massachusetts)
ABSTRACT In one aspect, the disclosure relates to a facile strategy to introduce electron-deficient aryl sulfate diesters to silylated hydroxyl groups of carbohydrates and amino acids, among other substrates, wherein selective hydrolysis and the removal of an electron-deficient aromatic group allows for the efficient generation of sulfated carbohydrates, peptides, and other compounds. The incorporation of electron-deficient aryl sulfate diesters in the early stage of the synthesis of glycans, peptides, and the like, disclosed herein avoids time-consuming protecting group manipulations, simplifies the purification of sulfated products, and improves the overall yield and efficiency. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
FILED Friday, May 08, 2020
APPL NO 16/869848
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 303/26 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 1/00 (20130101)
C07H 11/00 (20130101)
C07H 13/00 (20130101) Original (OR) Class

Steroids
C07J 41/0072 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505572 Fautsch et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Eye Institute (NEI)
APPLICANT(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota);  Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota);  Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Michael P. Fautsch (Rochester, Minnesota);  Peter Dosa (Vadnais Heights, Minnesota);  Michael A. Walters (Minneapolis, Minnesota);  Gunda I. Georg (St. Paul, Minnesota)
ABSTRACT The present invention provides benzothiadiazine and chroman derivatives and particularly diazoxide and cromakalim derivatives for use in treating glaucoma, retinopathy, treating age related macular degeneration, treating, stabilizing and/or inhibiting blood and lymph vascularization, and reducing intraocular pressure by administering a pharmaceutically effective amount of a prodrug disposed in an ophthalmically acceptable carrier to the eye, wherein the prodrug specifically modulates a KATP channel to reduce an intraocular pressure.
FILED Thursday, October 22, 2020
APPL NO 17/077859
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/00 (20130101)
A61K 9/0048 (20130101)
A61K 9/0051 (20130101)
A61K 31/353 (20130101)
A61K 31/454 (20130101)
A61K 31/549 (20130101)
A61K 31/675 (20130101)
A61K 31/4025 (20130101)
A61K 31/4439 (20130101)

Heterocyclic Compounds
C07D 201/00 (20130101)
C07D 285/24 (20130101)
C07D 311/20 (20130101)
C07D 311/70 (20130101)
C07D 405/04 (20130101)
C07D 405/12 (20130101)
C07D 405/14 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/6547 (20130101)
C07F 9/65586 (20130101)

Peptides
C07K 5/06026 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505574 Chen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Xinbin Chen (Davis, California);  Christopher A. Lucchesi (Davis, California);  Jin Zhang (Davis, California)
ABSTRACT The invention provides compositions and methods for preventing or treating cancer in a subject. In some embodiments, the compositions comprise isolated peptides and/or isolated oligonucleotides. In other embodiments, peptides of the present invention are conjugated with cell-penetrating peptides. Vectors, cells, and kits for preventing or treating cancer are also provided herein.
FILED Friday, May 24, 2019
APPL NO 16/422850
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 45/06 (20130101)
A61K 47/42 (20130101)
A61K 47/64 (20170801)
A61K 47/66 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 7/06 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505581 Peters et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) La Jolla Institute for Allergy and Immunology (La Jolla, California)
ASSIGNEE(S) La Jolla Institute for Allergy and Immunology (La Jolla, California)
INVENTOR(S) Bjoern Peters (La Jolla, California);  Alessandro Sette (La Jolla, California)
ABSTRACT The specificity of CD4+ TH responses of German cockroach (Bla g) antigens, and whether differences exist in magnitude or functionality as a function of disease severity, is disclosed. Also disclosed are novel German cockroach allergens and epitopes.
FILED Friday, May 13, 2016
APPL NO 15/574061
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/001 (20130101)
A61K 39/35 (20130101)
A61K 49/0004 (20130101)
A61K 49/0006 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 37/08 (20180101)

Peptides
C07K 14/435 (20130101)
C07K 14/43563 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5041 (20130101)
G01N 2800/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505585 Ulrichts et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) argenx BV (Zwijnaarde, Belgium);  THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S) argenx BV (Ghent, Belgium);  The Board of Regents of the University of Texas System (Austin, Texas)
INVENTOR(S) Peter Ulrichts (Destelbergeb, Belgium);  Christophe Blanchetot (Destellbergen, Belgium);  Torsten Dreier (Sint Martens Latem, Belgium);  Johannes de Haard (NA Oudelande, Netherlands);  E. Sally Ward Ober (Dallas, Texas);  Nicolas G. H. Ongenae (Ghent, Belgium)
ABSTRACT Provided are novel FcRn antagonist compositions comprising a variant Fc region that binds specifically to FcRn with increased affinity and reduced pH dependence relative to the native Fc region. Also provided are FcRn antagonists with enhanced CD16 binding affinity. Also provided are methods of treating antibody-mediated disorders (e.g. autoimmune diseases) using the these FcRn antagonist compositions, nucleic acids encoding the FcRn antagonist compositions, recombinant expression vectors and host cells for making the FcRn antagonist compositions, and pharmaceutical compositions comprising the FcRn antagonist compositions.
FILED Wednesday, November 22, 2017
APPL NO 15/821104
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/1709 (20130101)
A61K 45/06 (20130101)

Peptides
C07K 14/4703 (20130101) Original (OR) Class
C07K 2317/41 (20130101)
C07K 2317/52 (20130101)
C07K 2317/94 (20130101)
C07K 2317/524 (20130101)
C07K 2317/526 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505597 Marasco et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S) DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts)
INVENTOR(S) Wayne A. Marasco (Wellesley, Massachusetts);  Xianchun Tang (West Roxbury, Massachusetts)
ABSTRACT The present invention provides antibodies that neutralize MERS-CoV and methods of use thereof. The invented antibody is used to treat MERS-CoV infections and symptoms thereof.
FILED Wednesday, October 28, 2020
APPL NO 17/082865
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/507 (20130101)

Peptides
C07K 16/10 (20130101) Original (OR) Class
C07K 2317/13 (20130101)
C07K 2317/21 (20130101)
C07K 2317/34 (20130101)
C07K 2317/52 (20130101)
C07K 2317/56 (20130101)
C07K 2317/76 (20130101)
C07K 2317/92 (20130101)
C07K 2317/622 (20130101)
C07K 2319/40 (20130101)
C07K 2319/43 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2740/16043 (20130101)
C12N 2770/20022 (20130101)
C12N 2810/609 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/577 (20130101)
G01N 33/56983 (20130101)
G01N 2333/165 (20130101)
G01N 2469/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505598 Marks et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
Department of Health and Human Services (HHS)
Centers for Disease Control and Prevention (CDC)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) James D. Marks (San Francisco, California);  Maria Consuelo Garcia Rodriguez (San Francisco, California);  Jianbo Dong (San Francisco, California);  Zhengda Sun (San Francisco, California)
ABSTRACT The present disclosure provides antibodies that specifically bind to botulinum neurotoxins. The antibodies and derivatives thereof that specifically bind to the neutralizing epitopes provided herein can be used in methods to specifically bind and, in some embodiments, neutralize, botulinum neurotoxin and are therefore also useful in the treatment.
FILED Monday, January 28, 2019
APPL NO 16/259418
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)

Peptides
C07K 16/1282 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/533 (20130101)
G01N 33/549 (20130101)
G01N 33/563 (20130101)
G01N 33/56911 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505599 Scheinberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York);  EUREKA THERAPEUTICS, INC. (Emeryville, California)
ASSIGNEE(S) MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York);  EUREKA THERAPEUTICS, INC. (Emeryville, California)
INVENTOR(S) David A. Scheinberg (New York, New York);  Tao Dao (New York, New York);  Cheng Liu (Emeryville, California)
ABSTRACT The presently disclosed subject matter provides antigen-binding proteins (e.g., chimeric antigen receptors) and antibodies or antigen-binding portions thereof that bind to a Foxp3 peptide/MHC molecule complex. Such antibodies, fusion proteins and conjugates thereof are useful for inhibiting regulatory T cells and treating cancers.
FILED Friday, January 13, 2017
APPL NO 16/069999
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/6843 (20170801)
A61K 47/6849 (20170801)
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 16/18 (20130101) Original (OR) Class
C07K 16/30 (20130101)
C07K 16/468 (20130101)
C07K 16/2833 (20130101)
C07K 2317/31 (20130101)
C07K 2317/32 (20130101)
C07K 2317/33 (20130101)
C07K 2317/34 (20130101)
C07K 2317/73 (20130101)
C07K 2317/76 (20130101)
C07K 2317/92 (20130101)
C07K 2317/565 (20130101)
C07K 2317/622 (20130101)
C07K 2317/732 (20130101)
C07K 2319/03 (20130101)
C07K 2319/33 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6854 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505788 Iavarone et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Antonio Iavarone (New York, New York);  Anna Lasorella (New York, New York);  Raul Rabadan (New York, New York)
ABSTRACT The invention discloses oncogenic fusion proteins. The invention provides methods for treating gene-fusion based cancers.
FILED Friday, January 11, 2019
APPL NO 16/246167
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/47 (20130101)
A61K 31/53 (20130101)
A61K 31/404 (20130101)
A61K 31/496 (20130101)
A61K 31/506 (20130101)
A61K 31/517 (20130101)
A61K 31/519 (20130101)
A61K 31/4439 (20130101)
A61K 38/179 (20130101)
A61K 38/179 (20130101)
A61K 2300/00 (20130101)

Peptides
C07K 14/47 (20130101)
C07K 14/71 (20130101)
C07K 14/435 (20130101)
C07K 14/4738 (20130101)
C07K 16/40 (20130101)
C07K 2317/76 (20130101)
C07K 2319/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/12 (20130101) Original (OR) Class
C12N 9/16 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101)

Enzymes
C12Y 207/10001 (20130101)
C12Y 301/03003 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/573 (20130101)
G01N 33/57484 (20130101)
G01N 2333/71 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505794 St. Onge et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Robert P. St. Onge (Palo Alto, California);  Ulrich Schlecht (Palo Alto, California);  Sasha F. Levy (Stony Brook, New York);  Ronald W. Davis (Palo Alto, California);  Joseph Horecka (Fremont, California)
ABSTRACT A novel method for preparing sequence-verified oligonucleotides is disclosed. In particular, the invention relates to a simple, affordable, and scalable method that combines high-throughput mating of yeast clones, a unique selectable system for combining DNA sequences in yeast, and next-generation sequencing. This method allows sequence-verified oligonucleotides to be readily isolated from complex libraries.
FILED Wednesday, August 19, 2020
APPL NO 16/997586
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1031 (20130101)
C12N 15/1034 (20130101)
C12N 15/1034 (20130101)
C12N 15/1037 (20130101) Original (OR) Class
C12N 15/1058 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 2563/179 (20130101)
C12Q 2565/514 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505798 Carpenter et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Susan Carpenter (Santa Cruz, California);  Apple Vollmers (Santa Cruz, California);  Sergio Covarrubias (Santa Cruz, California)
ABSTRACT The disclosure is directed to inhibitory agents that hybridize to a GAPLINC RNA and inhibit or reduce the expression of the GAPLINC RNA. The GAPLINC RNA is a long non-coding RNA (lncRNA) located on chromosome 18 between the protein-coding genes Tgif and Dlgap1. The disclosure also features pharmaceutical compositions including the inhibitory agents and methods of using the inhibitory agents to treat an inflammatory disease, such as sepsis.
FILED Wednesday, September 23, 2020
APPL NO 17/029946
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 37/02 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/14 (20130101)
C12N 2310/113 (20130101)
C12N 2310/141 (20130101)
C12N 2310/321 (20130101)
C12N 2320/51 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505807 Khvorova et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Anastasia Khvorova (Westborough, Massachusetts);  Neil Aronin (Newtonville, Massachusetts);  Marie Cecile Didiot (Worcester, Massachusetts);  Reka Haraszti (Tubingen, Germany)
ABSTRACT In one aspect, the invention relates to a method of loading exosomes with oligonucleotide cargo, by incubating an oligonucleotide comprising one or more hydrophobic modifications with a population of exosomes for a period of time sufficient to allow loading of the exosomes with the oligonucleotide. Exosomes loaded with hydrophobically modified oligonucleotide cargo, and uses thereof, are also provided.
FILED Friday, December 13, 2019
APPL NO 16/714015
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 2267/0337 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/88 (20130101) Original (OR) Class
C12N 15/1137 (20130101)
C12N 2310/11 (20130101)
C12N 2310/14 (20130101)
C12N 2310/141 (20130101)
C12N 2310/311 (20130101)
C12N 2310/313 (20130101)
C12N 2310/315 (20130101)
C12N 2310/321 (20130101)
C12N 2310/322 (20130101)
C12N 2310/351 (20130101)
C12N 2310/531 (20130101)
C12N 2310/3181 (20130101)
C12N 2310/3231 (20130101)
C12N 2310/3515 (20130101)
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US 11505818 Celedon et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Scanogen Inc. (Baltimore, Maryland)
ASSIGNEE(S) Scanogen Inc. (Baltimore, Maryland)
INVENTOR(S) Alfredo Andres Celedon (Columbia, Maryland);  Saravana Radha Krishna Murthy (Gaithersburg, Maryland);  Zhiguang Xu (Baltimore, Maryland);  Danielle Elise Schultz (Gaithersburg, Maryland);  Troy Allen Horn (Reisterstown, Maryland)
ABSTRACT The present application relates to detection units and methods for detecting one or more target analytes in a sample using a complex formed by a target and first and second probes, wherein the complex comprises an elongated region, a particle that is coupled to the first probe, and a solid support that is coupled to the second probe. Specific binding of a target analyte can be distinguished from non-specific binding of the particle by measuring the displacement of the particle.
FILED Wednesday, December 12, 2018
APPL NO 16/217253
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6816 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/745 (20130101)
G01N 27/3271 (20130101)
G01N 27/3276 (20130101)
G01N 27/4145 (20130101)
G01N 33/54306 (20130101)
G01N 33/54313 (20130101)
G01N 33/54326 (20130101)
G01N 33/54373 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505831 Liu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts)
ASSIGNEE(S) DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts)
INVENTOR(S) Xiaole Liu (Wayland, Massachusetts);  Peng Jiang (Boston, Massachusetts)
ABSTRACT The present invention relates to gene expression signatures that predict response and resistance to targeted therapy and immunotherapy.
FILED Tuesday, December 18, 2018
APPL NO 16/223470
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/106 (20130101)
C12Q 2600/158 (20130101)
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US 11506661 Han
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) Yiping Han (Bronx, New York)
ASSIGNEE(S) The Trustees of Columbia University In the City of New York (New York, New York)
INVENTOR(S) Yiping Han (Bronx, New York)
ABSTRACT The present invention relates to detecting serum anti-FadA antibodies in test samples from a patient. Additionally, aspects of the present invention provide the basis for detection of serum anti-FadA antibody levels from test samples and correlation with various conditions of clinical relevance.
FILED Thursday, May 03, 2018
APPL NO 15/970391
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 16/12 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56916 (20130101) Original (OR) Class
G01N 33/57419 (20130101)
G01N 33/57484 (20130101)
G01N 2469/20 (20130101)
G01N 2800/60 (20130101)
G01N 2800/065 (20130101)
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US 11506666 Bigner et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Duke University (Durham, North Carolina)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Darell D. Bigner (Mebane, North Carolina);  Vidyalakshmi Chandramohan (Durham, North Carolina);  Matthias Gromeier (Durham, North Carolina)
ABSTRACT A reliable assay to specifically detect CD155 in tissue sections has widespread use because CD155 is expressed widely among tumor types. Additionally, detected expression of CD 155 in glioblastoma cells is at levels commensurate with susceptibility to PVSRIPO (a poliovirus construct) infection and killing. An anti-CD155 antibody can achieve mono-specific detection of CD155 in immunoblots of tumor homogenates and immunohistochemistry of tumor formalin fixed, paraffin embedded sections. The assay can be used to determine appropriate use of PVSRIPO in oncolytic immunotherapy against cancers.
FILED Monday, October 02, 2017
APPL NO 16/340026
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 16/2896 (20130101)
C07K 2317/20 (20130101)
C07K 2317/34 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/60 (20130101)
G01N 33/582 (20130101)
G01N 33/57484 (20130101) Original (OR) Class
G01N 2333/908 (20130101)
G01N 2333/70596 (20130101)
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US 11506670 Aye et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Cornell University (Ithaca, New York)
ASSIGNEE(S) CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S) Yimon Aye (Ithaca, New York);  Marcus J. C. Long (Ithaca, New York);  Yi Zhao (Ithaca, New York)
ABSTRACT The present invention relates to a method for identifying endogenous first responder protein-cysteines. Methods for screening candidate compounds suitable for regulating NF-kB signaling and the DNA damage response pathway are also disclosed.
FILED Friday, February 23, 2018
APPL NO 15/903506
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/68 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/58 (20130101)
G01N 33/566 (20130101)
G01N 33/6842 (20130101) Original (OR) Class
G01N 2458/00 (20130101)
G01N 2500/04 (20130101)
G01N 2500/10 (20130101)
G01N 2570/00 (20130101)
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US 11507737 Jain et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Vignet Incorporated (Fairfax, Virginia)
ASSIGNEE(S) VigNet Incorporated (Fairfax, Virginia)
INVENTOR(S) Praduman Jain (Fairfax, Virginia);  Dave Klein (Oakton, Virginia);  Neeta Jain (Fairfax, Virginia);  Yue Cao (Vienna, Virginia)
ABSTRACT In some implementations, a system dynamically adjusts an electronic form of an application based on user data and form data specified for the electronic form. Form data that specifies characteristics of the electronic form is initially received by a computing device. The form data specifies one or more rules configured to vary the content of the electronic form that is presented for different users. User data indicating characteristics of a user is then obtained by the computing device. An interactive element is then selected from among a set of multiple interactive elements based on the received user data and the rules in the received form data. A view of the electronic form is customized for the user by including, in the customized view, the interactive element. The view of the customized electronic form is then displayed by the computing device.
FILED Thursday, April 29, 2021
APPL NO 17/244131
ART UNIT 2144 — Graphical User Interface and Document Processing
CURRENT CPC
Electric Digital Data Processing
G06F 40/103 (20200101)
G06F 40/131 (20200101)
G06F 40/174 (20200101) Original (OR) Class
G06F 40/186 (20200101)
G06F 40/197 (20200101)
G06F 40/226 (20200101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 10/20 (20180101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/06 (20130101)
H04L 67/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11508051 Lee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Leica Microsystems CMS GmbH (Wetzlar, Germany)
ASSIGNEE(S) LEICA MICROSYSTEMS CMS GMBH (Wetzlar, Germany)
INVENTOR(S) Shih-Jong James Lee (Bellevue, Washington);  Hideki Sasaki (Bellevue, Washington)
ABSTRACT A computerized model compatibility regulation method for imaging applications first performs a target domain B application by computing means using at least one image X and target domain B image analytics to generate a target domain B application output for X. The method then applies a reference domain A application by computing means to generate reference domain A application output for X. The method further performs a compatibility assessment to generate at least one compatibility result for X. In addition, the method checks the compatibility result for X and if the check output is incompatible, the method performs online correction to generate a corrected application output for X.
FILED Friday, June 05, 2020
APPL NO 16/894708
ART UNIT 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 20/00 (20190101)

Image Data Processing or Generation, in General
G06T 7/0002 (20130101) Original (OR) Class
G06T 2207/20081 (20130101)
G06T 2207/20084 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11508063 Buckler
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) ELUCID BIOIMAGING INC. (Boston, Massachusetts)
ASSIGNEE(S) ELUCID BIOIMAGING INC. (Boston, Massachusetts)
INVENTOR(S) Andrew J. Buckler (Boston, Massachusetts)
ABSTRACT A system including a hierarchical analytics framework that can utilize a first set of machine learned algorithms to identify and quantify a set of biological properties utilizing medical imaging data is provided. System can segment the medical imaging data based on the quantified biological properties to delineate existence of perivascular adipose tissue. The system can also segment the medical imaging data based on the quantified biological properties to determine a lumen boundary and/or determine a cap thickness based on a minimum distance between the lumen boundary and LRNC regions.
FILED Tuesday, August 04, 2020
APPL NO 16/984640
ART UNIT 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/02007 (20130101)
A61B 6/504 (20130101)
A61B 8/0891 (20130101)

Image Data Processing or Generation, in General
G06T 7/11 (20170101)
G06T 7/0012 (20130101) Original (OR) Class
G06T 2207/30101 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11508858 Goldan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) The Research Foundation for The State University of New York (Albany, New York)
ASSIGNEE(S) The Research Foundation for The State University of New York (Albany, New York)
INVENTOR(S) Amirhossein Goldan (Stony Brook, New York);  Wei Zhao (East Setauket, New York)
ABSTRACT Provided is a field shaping multi-well detector and method of fabrication thereof. The detector is configured by depositing a pixel electrode on a substrate, depositing a first dielectric layer, depositing a first conductive grid electrode layer on the first dielectric layer, depositing a second dielectric layer on the first conductive grid electrode layer, depositing a second conductive grid electrode layer on the second dielectric layer, depositing a third dielectric layer on the second conductive grid electrode layer, depositing an etch mask on the third dielectric layer. Two pillars are formed by etching the third dielectric layer, the second conductive grid electrode layer, the second dielectric layer, the first conductive grid electrode layer, and the first dielectric layer. A well between the two pillars is formed by etching to the pixel electrode, without etching the pixel electrode, and the well is filled with a-Se.
FILED Tuesday, December 01, 2020
APPL NO 17/108094
ART UNIT 2892 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/1461 (20130101)
H01L 27/1463 (20130101)
H01L 27/14612 (20130101)
H01L 27/14632 (20130101)
H01L 27/14636 (20130101)
H01L 27/14643 (20130101)
H01L 27/14659 (20130101)
H01L 27/14692 (20130101)
H01L 27/14696 (20130101)
H01L 31/105 (20130101)
H01L 31/107 (20130101)
H01L 31/0272 (20130101) Original (OR) Class
H01L 31/0376 (20130101)
H01L 31/02161 (20130101)
H01L 31/022408 (20130101)
H01L 31/035209 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE49304 Gao et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
APPLICANT(S) University of Washington through its Center for Commercialization (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Xiaohu Gao (Shoreline, Washington);  Pavel Zrazhevskiy (Redmond, Washington)
ABSTRACT Provided herein are compositions and methods for identifying or quantitating one or more analytes in sample. The composition can comprise an affinity molecule reversibly conjugated to a label moiety via a double-stranded nucleic acid linker or via an adaptor molecule. The affinity molecule and the label moiety can be linked to different strands of the double-stranded nucleic acid linker. Compositions can be used in any biological assays for detection, identification and/or quantification of target molecules or analytes, including multiplex staining for molecular profiling of individual cells or cellular populations. For example, the compositions can be adapted for use in immunofluorescence, fluorescence in situ hybridization, immunohistochemistry, western blot, and the like.
FILED Friday, April 03, 2020
APPL NO 16/840107
ART UNIT 3991 — Central Reexamination Unit (Chemical)
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6804 (20130101)
C12Q 1/6804 (20130101)
C12Q 1/6841 (20130101) Original (OR) Class
C12Q 2563/155 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/587 (20130101)
G01N 33/588 (20130101)
G01N 2458/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 11504012 Cho
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh (Pittsburgh, Pennsylvania)
INVENTOR(S) Sung Kwon Cho (Pittsburgh, Pennsylvania)
ABSTRACT A diaphragm-based sensor includes a deflectable diaphragm, a base layer opposite the diaphragm, and a corrugated wall extending between the diaphragm and the base layer. The diaphragm is suspended over a cavity enclosed by the diaphragm, the base layer and the corrugated wall. The diaphragm includes a first electrode and the base layer includes a second electrode such that a capacitance between the first and second electrodes changes when the diaphragm is deflected relative to the cavity.
FILED Wednesday, January 22, 2020
APPL NO 16/749247
ART UNIT 2814 — Semiconductors/Memory
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0215 (20130101) Original (OR) Class
A61B 2562/125 (20130101)

Microstructural Devices or Systems, e.g Micromechanical Devices
B81B 3/0021 (20130101)
B81B 2201/0264 (20130101)
B81B 2203/0127 (20130101)
B81B 2203/0315 (20130101)

Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems
B81C 1/00158 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504135 Kosiorek et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Alphapointe (Kansas City, Missouri)
ASSIGNEE(S) ALPHAPOINTE (Kanasas City, Missouri);  THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE ARMY (Fort Detrick, Maryland)
INVENTOR(S) Christopher B. Kosiorek (La Vernia, Texas);  Ryan Williams (Olathe, Kansas);  Esra Abir (New York, New York);  Brenda Mee (West Newfield, Maine);  Dexter C. Drayton (Harrisburg, North Carolina);  Neslihan Damar (Concord, North Carolina);  Nilufer Polat (Harrisburg, North Carolina);  Yavuz Avci (Harrisburg, North Carolina)
ABSTRACT A pre-fabricated tourniquet that is easy to apply, that ensures consistent and even circumferential pressure, that is lightweight, that provides standard life saving operation, and that can be utilized in any setting or situation, and related methods are provided. Mechanically constricting tourniquet apparatus and related methods are provided that are comprised of a tourniquet body, a carriage, a torsion bar, a receiver, and a slider. The tourniquet is long enough to encircle a human limb, for example, an arm or leg. The tourniquet apparatus includes several features for preventing or otherwise limiting harm to users and/or damage to the tourniquet apparatus itself.
FILED Thursday, February 13, 2020
APPL NO 16/790536
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/1325 (20130101) Original (OR) Class
A61B 2017/00526 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504196 Palmowski et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Telemedicine and Advanced Technology Research Center (TATRC)
APPLICANT(S) Board of Regents of the University of Nebraska (Lincoln, Nebraska)
ASSIGNEE(S) Board of Regents of the University of Nebraska (Lincoln, Nebraska)
INVENTOR(S) Joseph Palmowski (Pasadena, California);  Shane Farritor (Lincoln, Nebraska)
ABSTRACT Disclosed herein are various robotic surgical devices and systems that include first and second elongate bodies, first and second driveshafts disposed through the second elongate body, and an in-line shoulder joint with a robotic arm coupled thereto. In certain implementations, the in-line shoulder joint has a differential yoke and a dual shaft disposed within the yoke lumen.
FILED Wednesday, April 21, 2021
APPL NO 17/236489
ART UNIT 3658 — Material and Article Handling
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 34/30 (20160201) Original (OR) Class
A61B 2034/305 (20160201)

Manipulators; Chambers Provided With Manipulation Devices
B25J 9/102 (20130101)
B25J 9/126 (20130101)
B25J 17/0258 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504438 Lakshmanan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Anupama Lakshmanan (Pasadena, California);  Arash Farhadi (Pasadena, California);  Suchita P. Nety (Sunnyvale, California);  Raymond W. Bourdeau (Watertown, Massachusetts);  Mikhail Shapiro (Los Angeles, California)
ABSTRACT Gas vesicles, protein variants and related compositions methods and systems for singleplexed and/or multiplexed ultrasound imaging of a target site in which a gas vesicle provides contrast for the imaging which is modifiable by application of a selectable acoustic collapse pressure value of the gas vesicle.
FILED Thursday, October 17, 2019
APPL NO 16/656417
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 8/481 (20130101)
A61B 8/5238 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 49/0002 (20130101)
A61K 49/0045 (20130101)
A61K 49/0093 (20130101)
A61K 49/221 (20130101)
A61K 49/223 (20130101) Original (OR) Class

Peptides
C07K 14/195 (20130101)
C07K 2319/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504673 Peterson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Aberdeen Proving Ground (APG)
Research, Development and Engineering Command (RDECOM)
Edgewood Chemical Biological Center (ECBC)
Defense Threat Reduction Agency (DTRA)
APPLICANT(S) University of Delaware (Newark, Delaware);  Government of the United States, as Represented by the Defense Threat Reduction Agency (Fort Belvoir, Virginia);  Government of the United States, as Represented by the Secretary of the Army (Aberdeen Proving Ground, Maryland)
ASSIGNEE(S) GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE DEFENSE THREAT REDUCTION AGENCY (Fort Belvoir, Virginia);  GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY (Aberdeen Proving Ground, Maryland);  UNIVERSITY OF DELAWARE (Newark, Delaware)
INVENTOR(S) Gregory W. Peterson (Bel Air, Maryland);  Annie Lu (Washington, District of Columbia);  Thomas H. Epps, III (Bear, Delaware);  Jean S. Epps (Bear, Delaware)
ABSTRACT Disclosed herein are multi-layer structures comprising a first composite layer disposed over a second composite layer, wherein the first composite layer contains a first active material dispersed in a first polymer containing an elastomeric polymer and the second composite layer contains a second polymer which may have a second active material dispersed therein, wherein the first active material chemically or physically interacts with at least one toxic chemical and is selected from the group consisting of metal-organic frameworks (MOFs), metal oxides, metal hydroxides, zeolites, and combinations thereof, and wherein the active material and the second active material (if present) are the same as or different from each other, and the first polymer and second polymer are the same as or different from each other, subject to the proviso that the first composite layer and the second composite layer compositionally differ from each other in at least one respect.
FILED Wednesday, August 15, 2018
APPL NO 16/638817
ART UNIT 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 53/228 (20130101)
B01D 67/0079 (20130101)
B01D 69/12 (20130101) Original (OR) Class
B01D 69/148 (20130101)
B01D 71/022 (20130101)
B01D 71/80 (20130101)
B01D 2325/20 (20130101)
B01D 2325/40 (20130101)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 7/12 (20130101)
B32B 27/08 (20130101)
B32B 27/18 (20130101)
B32B 27/302 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504676 Bishop
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Hamilton Sundstrand Corporation (Charlotte, North Carolina)
ASSIGNEE(S) Hamilton Sundstrand Corporation (Charlotte, North Carolina)
INVENTOR(S) Benjamin E. Bishop (South Glastonbury, Connecticut)
ABSTRACT A method for controlling the saturation level of gas in a liquid discharge includes obtaining temperature and pressure measurements of a solvent in a mixing vessel and obtaining a pressure measurement of a source feedstock in a feedstock tank, correlating the temperature and pressure measurements of the solvent to baseline data to generate a theoretical uptake rate for the source feedstock into the solvent and a theoretical flow rate of the source feedstock into the mixing vessel, and determining a required opening setting for a feedstock valve in the feedstock input line in order to achieve a desired liquid displacement in the mixing vessel. The method includes determining an uptake duration and achieving an uptake displacement equivalent to the reverse of the desired liquid displacement. The method includes generating a valve operating control law for how the feedstock valve should function in a cycle.
FILED Wednesday, January 13, 2021
APPL NO 17/148068
ART UNIT 1748 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Mixing, e.g Dissolving, Emulsifying, Dispersing
B01F 21/02 (20220101)
B01F 21/30 (20220101) Original (OR) Class
B01F 23/23 (20220101)
B01F 23/29 (20220101)
B01F 23/231 (20220101)
B01F 23/2341 (20220101)
B01F 35/2112 (20220101)
B01F 35/2113 (20220101)
B01F 35/2115 (20220101)
B01F 35/2212 (20220101)

Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers
B63G 8/08 (20130101)

Gas-flow Silencers or Exhaust Apparatus for Machines or Engines in General; Gas-flow Silencers or Exhaust Apparatus for Internal Combustion Engines
F01N 3/04 (20130101)
F01N 9/00 (20130101)
F01N 13/12 (20130101)
F01N 2590/02 (20130101)

Systems for Controlling or Regulating Non-electric Variables
G05D 21/02 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 10/12 (20130101)
Y02T 10/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504899 Tan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Loon-Seng Tan (Centerville, Ohio);  David H. Wang (Beavercreek, Ohio)
ABSTRACT The invention generally relates to shape memory films that are tri-functionally crosslinked and that comprise multiple, non-terminal, phenylethynyl moieties. In addition, the present invention relates methods of fabricating such films. Due to the improved properties of such SMPS, the SMP designer can program in to the SMP mechanical property enhancements that make the SMP suitable, among other things, for advanced sensors, high temperature actuators, responder matrix materials and heat responsive packaging.
FILED Monday, January 27, 2020
APPL NO 16/752737
ART UNIT 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 35/02 (20130101)
B29C 41/02 (20130101)
B29C 41/003 (20130101)
B29C 41/12 (20130101)
B29C 41/42 (20130101)
B29C 41/46 (20130101)
B29C 53/04 (20130101)
B29C 53/005 (20130101) Original (OR) Class
B29C 2791/001 (20130101)
B29C 2791/004 (20130101)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2079/08 (20130101)
B29K 2105/24 (20130101)
B29K 2105/0061 (20130101)
B29K 2995/0094 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 73/14 (20130101)
C08G 73/101 (20130101)
C08G 73/121 (20130101)
C08G 73/124 (20130101)
C08G 73/127 (20130101)
C08G 73/1067 (20130101)
C08G 73/1071 (20130101)
C08G 2220/00 (20130101)
C08G 2280/00 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 5/02 (20130101)
C08J 2379/08 (20130101)

Compositions of Macromolecular Compounds
C08L 2201/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505283 Seeley
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Keyport, Washington)
INVENTOR(S) Eric Seeley (Seabeck, Washington)
ABSTRACT A field configurable autonomous vehicle includes modular elements and attachable components. The vehicle can be assembled from these modular elements and components to meet desired mission and performance characteristics without the need to purchase specially designed vehicles for each mission. The vehicle can include a mechanisms that magnetically attach and release configurable elements from the vehicle.
FILED Saturday, September 12, 2020
APPL NO 16/974045
ART UNIT 3617 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Ships or Other Waterborne Vessels; Equipment for Shipping
B63B 3/08 (20130101) Original (OR) Class
B63B 7/04 (20130101)
B63B 73/10 (20200101)

Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers
B63G 2008/002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505296 Seeley
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Keyport, Washington)
INVENTOR(S) Eric Seeley (Seabeck, Washington)
ABSTRACT A field configurable autonomous vehicle includes modular elements and attachable components. The vehicle can be assembled from these modular elements and components to meet desired mission and performance characteristics without the need to purchase specially designed vehicles for each mission. The vehicle can include a mechanisms that magnetically attach and release payloads such as cargo or ballast from the vehicle.
FILED Saturday, September 12, 2020
APPL NO 16/974042
ART UNIT 3617 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Ships or Other Waterborne Vessels; Equipment for Shipping
B63B 13/00 (20130101)
B63B 25/002 (20130101)

Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers
B63G 8/001 (20130101) Original (OR) Class
B63G 2008/002 (20130101)

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 1/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505312 Kogan
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S) LOCKHEED MARTIN CORPORATION (Bethesda, Maryland)
ASSIGNEE(S) LOCKHEED MARTIN CORPORATION (Bethesda, Maryland)
INVENTOR(S) Anatoly Kogan (New Rochelle, New York)
ABSTRACT A damper assembly includes a housing defining at least one or more cavities. A piston is in operable communication with the housing. A rod end is operatively coupled to the piston, the rod end having at least two cartridges.
FILED Monday, April 22, 2019
APPL NO 16/390455
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeroplanes; Helicopters
B64C 27/001 (20130101) Original (OR) Class
B64C 27/04 (20130101)
B64C 2027/003 (20130101)

Springs; Shock-absorbers; Means for Damping Vibration
F16F 13/04 (20130101)
F16F 2232/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505502 Xu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Florida State University Research Foundation, Inc. (Tallahassee, Florida);  The Government of the United States of America as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) Florida State University Research Foundation, Inc. (Tallahassee, Florida);  The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) Chengying Xu (Tallahassee, Florida);  William C. Nickerson (Ashburn, Virginia)
ABSTRACT Hybrid composite materials including carbon nanotube sheets and flexible ceramic materials, and methods of making the same are provided herein. In one embodiment, a method of forming a hybrid composite material is provided, the method including: placing a layer of a first flexible ceramic composite on a lay-up tooling surface; applying a sheet of a pre-preg carbon fiber reinforced polymer on the flexible ceramic composite; curing the flexible ceramic composite and the pre-preg carbon fiber reinforced polymer sheet together to form a hybrid composite material; and removing the hybrid composite material from the lay-up tooling surface, wherein the first flexible ceramic composite comprises an exterior surface of the hybrid composite material.
FILED Tuesday, October 24, 2017
APPL NO 15/791661
ART UNIT 1783 — Miscellaneous Articles, Stock Material
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 70/30 (20130101)
B29C 70/78 (20130101)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 5/022 (20130101)
B32B 9/007 (20130101)
B32B 18/00 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)

Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/80 (20130101) Original (OR) Class
C04B 35/589 (20130101)
C04B 41/85 (20130101)
C04B 41/4501 (20130101)
C04B 41/5001 (20130101)
C04B 2235/77 (20130101)
C04B 2235/95 (20130101)
C04B 2235/96 (20130101)
C04B 2235/616 (20130101)
C04B 2235/3217 (20130101)
C04B 2235/5288 (20130101)
C04B 2235/9607 (20130101)
C04B 2235/9615 (20130101)
C04B 2235/9684 (20130101)
C04B 2237/38 (20130101)
C04B 2237/365 (20130101)
C04B 2237/368 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/30 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505556 Chavez et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Xalud Therapeutics, Inc. (Berkeley, California)
ASSIGNEE(S) Xalud Therapeutics, Inc. (Berkeley, California)
INVENTOR(S) Raymond A. Chavez (Alameda, California);  Stephen Collins (Lake Forest, Illinois)
ABSTRACT The present invention encompasses improved morphian compositions and methods of use of the improved compositions for modulating neuropathic pain, opioid-induced glial activation, or a combination thereof beyond what is currently known in the art. The methods involve administering the compound of Formula I to a subject.
FILED Wednesday, December 12, 2018
APPL NO 16/772108
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/02 (20180101)
A61P 25/04 (20180101)

General Methods of Organic Chemistry; Apparatus Therefor
C07B 2200/07 (20130101)

Heterocyclic Compounds
C07D 489/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505597 Marasco et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S) DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts)
INVENTOR(S) Wayne A. Marasco (Wellesley, Massachusetts);  Xianchun Tang (West Roxbury, Massachusetts)
ABSTRACT The present invention provides antibodies that neutralize MERS-CoV and methods of use thereof. The invented antibody is used to treat MERS-CoV infections and symptoms thereof.
FILED Wednesday, October 28, 2020
APPL NO 17/082865
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/507 (20130101)

Peptides
C07K 16/10 (20130101) Original (OR) Class
C07K 2317/13 (20130101)
C07K 2317/21 (20130101)
C07K 2317/34 (20130101)
C07K 2317/52 (20130101)
C07K 2317/56 (20130101)
C07K 2317/76 (20130101)
C07K 2317/92 (20130101)
C07K 2317/622 (20130101)
C07K 2319/40 (20130101)
C07K 2319/43 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2740/16043 (20130101)
C12N 2770/20022 (20130101)
C12N 2810/609 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/577 (20130101)
G01N 33/56983 (20130101)
G01N 2333/165 (20130101)
G01N 2469/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505598 Marks et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
Department of Health and Human Services (HHS)
Centers for Disease Control and Prevention (CDC)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) James D. Marks (San Francisco, California);  Maria Consuelo Garcia Rodriguez (San Francisco, California);  Jianbo Dong (San Francisco, California);  Zhengda Sun (San Francisco, California)
ABSTRACT The present disclosure provides antibodies that specifically bind to botulinum neurotoxins. The antibodies and derivatives thereof that specifically bind to the neutralizing epitopes provided herein can be used in methods to specifically bind and, in some embodiments, neutralize, botulinum neurotoxin and are therefore also useful in the treatment.
FILED Monday, January 28, 2019
APPL NO 16/259418
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)

Peptides
C07K 16/1282 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/533 (20130101)
G01N 33/549 (20130101)
G01N 33/563 (20130101)
G01N 33/56911 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505722 Moore et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S) THE BOEING COMPANY (Chicago, Illinois)
ASSIGNEE(S) THE BOEING COMPANY (Chicago, Illinois)
INVENTOR(S) James A. Moore (Gilbert, Arizona);  Daniel W. Huff (Scottsdale, Arizona);  Dennis K. Kennedy (Mesa, Arizona)
ABSTRACT The present disclosure provides methods for forming sol-gels, sol-gel films and substrates, such as vehicle components, having a sol-gel film disposed thereon. At least one method of forming a sol-gel includes mixing a metal alkoxide, an acid stabilizer, and an organic solvent to form a first mixture having about 10 wt % or less water content based on the total weight of the first mixture. The method includes mixing an organosilane with the first mixture to form a second mixture having about 10 wt % or less water content based on the total weight of the second mixture.
FILED Monday, December 11, 2017
APPL NO 15/837058
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 13/003 (20130101)
B01J 13/0065 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 1/00 (20130101)
C09D 5/08 (20130101)

Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives
C09J 5/02 (20130101)
C09J 9/00 (20130101) Original (OR) Class
C09J 11/06 (20130101)
C09J 2400/163 (20130101)
C09J 2400/166 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 18/122 (20130101)
C23C 18/1216 (20130101)
C23C 18/1241 (20130101)
C23C 18/1254 (20130101)
C23C 22/73 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505773 Varone et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S) Antonio Varone (Newton, Massachusetts);  Norman Wen (Newton, Massachusetts);  Daniel Levner (Brookline, Massachusetts);  Richard Novak (Jamaica Plain, Massachusetts);  Lori McPartlin (North Billerica, Massachusetts);  Donald E. Ingber (Boston, Massachusetts);  Youngjae Choe (Somerville, Massachusetts);  Lian Leng (LaSalle, Canada);  Justin K. Nguyen (Medford, Massachusetts)
ABSTRACT A device for simulating a function of a tissue includes a first structure, a second structure, and a membrane. The first structure defines a first chamber. The first chamber includes a matrix disposed therein and an opened region. The second structure defines a second chamber. The membrane is located at an interface region between the first chamber and the second chamber. The membrane includes a first side facing toward the first chamber and a second side facing toward the second chamber. The membrane separates the first chamber from the second chamber.
FILED Friday, December 02, 2016
APPL NO 15/781078
ART UNIT 1799 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5027 (20130101)
B01L 2300/069 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 3/04 (20130101)
C12M 21/08 (20130101)
C12M 23/16 (20130101) Original (OR) Class
C12M 25/02 (20130101)
C12M 25/14 (20130101)
C12M 29/10 (20130101)
C12M 41/46 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/069 (20130101)
C12N 5/0629 (20130101)
C12N 5/0656 (20130101)
C12N 5/0679 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505874 Woodrow, III et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) The Boeing Company (Chicago, Illinois)
ASSIGNEE(S) THE BOEING COMPANY (Chicago, Illinois)
INVENTOR(S) Thomas A. Woodrow, III (Lakeside, Texas);  Jean A. Nielsen (Kent, Washington)
ABSTRACT The present disclosure generally relates to the field of tin electroplating. More specifically, the present disclosure relates to methods for mitigating tin whisker formation on tin-plated films and tin-plated surfaces by doping the tin with germanium.
FILED Thursday, March 19, 2020
APPL NO 16/824399
ART UNIT 1784 — Miscellaneous Articles, Stock Material
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 15/00 (20130101)
B32B 15/01 (20130101)
B32B 2307/538 (20130101)
B32B 2457/00 (20130101)

Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 3/30 (20130101) Original (OR) Class
C25D 3/60 (20130101)
C25D 5/56 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/12715 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11506254 Esplin et al.
FUNDED BY
Department of Defense (DOD)
Missile Defense Agency (MDA)
APPLICANT(S) Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Roger C. Esplin (Marana, Arizona);  Peter H. Vo (Oro Valley, Arizona)
ABSTRACT A low-profile shock isolating payload mounting assembly comprises a first mount, a second mount, and an isolator. The second mount is movable relative to the first mount and comprises a riser comprising an inclined surface. The isolator comprises an inner frame and an outer frame. The inner frame couples to the first mount and comprises a platform and a leg extending from the platform. The leg is inclined to be complementary to the inclined surface of the second mount. The outer frame couples to the second mount and comprises an opening for accessing the platform of the inner frame. The rail is inclined so as to be complementary to the leg to capture the leg between the rail of the outer frame and the inclined surface of the second mount. The isolator operates to dampen vibrations and shocks propagating between the first and second mounts.
FILED Tuesday, May 26, 2020
APPL NO 16/883912
ART UNIT 3632 — Static Structures, Supports and Furniture
CURRENT CPC
Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles
B60K 5/1208 (20130101)

Springs; Shock-absorbers; Means for Damping Vibration
F16F 15/022 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11506465 Foltz et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America as Represented by the Secretary of the Navy (Indian Head, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Lee Foltz (Indian Head, Maryland);  Adam J. Pegouske (White Plains, Maryland);  Daniel McCarthy (LaPlata, Maryland);  George R. Torres (Hughesville, Maryland)
ABSTRACT Explosive devices may be formed from hollow members filled with explosive materials. The hollow members may be made of mating halves that are packed or loaded with explosive material prior to the mating halves being joined together. In some exemplary aspects, the hollow members are placed in fluid-filled containers such that the explosive reaction creates a wave of fluid that impacts a target. Components of the devices may be COTS items and items that may be manufacture with 3D printers.
FILED Thursday, July 30, 2020
APPL NO 16/873856
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Weapons for Projecting Missiles Without Use of Explosive or Combustible Propellant Charge; Weapons Not Otherwise Provided for
F41B 9/0046 (20130101) Original (OR) Class

Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 3/00 (20130101)
F42B 3/02 (20130101)
F42B 3/24 (20130101)
F42B 33/06 (20130101)

Blasting
F42D 1/043 (20130101)
F42D 3/00 (20130101)
F42D 5/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11506474 Goss et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) AURA Technologies, LLC (Raleigh, North Carolina)
ASSIGNEE(S) AURA Technologies, LLC (Carrboro, North Carolina)
INVENTOR(S) Garrett Goss (Cary, North Carolina);  Alex Blate (Raleigh, North Carolina)
ABSTRACT Fuze assembly methods and devices. The methods include providing a firing pin to detonate the projectile; operably connecting a weighted body to the firing pin; and operably connecting a flexural portion to the weighted body to retain position of the weighted body due to centrifugal force generated by the rotation of the projectile to retain the firing pin in a detonation prevention position and move the weighted body to drive the firing pin to a detonation position upon impact of the projectile.
FILED Friday, June 03, 2022
APPL NO 17/832012
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ammunition Fuzes; Arming or Safety Means Therefor
F42C 1/04 (20130101)
F42C 15/26 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11506752 Jolly et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
ASSIGNEE(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S) James R. Jolly (Merrimack, New Hampshire);  Lynn M. Shepard (Litchfield, New Hampshire);  Richard B. Elder, Jr. (Bedford, New Hampshire);  Richard A. Faust, III (Salem, New Hampshire);  Susan F. Lindemann (Derry, New Hampshire)
ABSTRACT An emitter ID ambiguity reduction system includes a Mission Data File Ambiguity Resolution matrix that contains both a) the INTEL-based emitter parameters data necessary to break emitter-by-emitter ambiguities, and b) the action(s) the Electronic Warfare (EW) system is to take to collect that data. Control software is triggered via either external command or per Mission Data File information (such as that contained in the Ambiguity Resolution Matrix). The emitter ID ambiguity reduction system includes Data collection hardware and firmware and Data Analysis OFP software algorithm(s).
FILED Monday, April 20, 2020
APPL NO 16/764241
ART UNIT 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 45/0015 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/41 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11506841 Ramachandran et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
Office of Science (DOE-SC)
Brookhaven National Laboratory (BNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Brookhaven Science Associates, LLC (BSA) at Upton, NY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Trustees of Boston University (Boston, Massachusetts)
ASSIGNEE(S) Trustees of Boston University (Boston, Massachusetts)
INVENTOR(S) Siddharth Ramachandran (Boston, Massachusetts);  Zelin Ma (Boston, Massachusetts)
ABSTRACT An optical fiber system exploits a principle of topological confinement for guided higher-order modes, in contrast to more conventional total-internal-reflection (TIR) confinement. The optical fiber has a geometry and index profile defining a cutoff wavelength for a predetermined L-mode of optical signal propagation in the optical fiber, where L is azimuthal mode index. An optical source subsystem is coupled to the optical fiber to establish an optical signal propagating in the optical fiber, wherein the optical signal has the predetermined L-mode and a wavelength being either (1) at least 15% above the cutoff wavelength such that the optical beam propagates as a topologically confined mode, or (2) sufficiently above the cutoff wavelength that, based on the L-mode of the optical beam, the optical beam propagates as a topologically confined mode having propagation loss less than 3 dB/meter.
FILED Sunday, May 09, 2021
APPL NO 17/315314
ART UNIT 2883 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/14 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11506951 Ram et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Aeronautics and Space Administration (NASA)
Jet Propulsion Laboratory (JPL)
Federally Funded Research and Development Center (FFRDC)
Operated by California Institute of Technology (CALTECH) at Pasadena, CA
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Rajeev J. Ram (Arlington, Massachusetts);  Dodd Joseph Gray (San Francisco, California);  Amir H. Atabaki (San Francisco, California);  Marc De Cea Falco (Cambridge, Massachusetts)
ABSTRACT Optical read-out of a cryogenic device (such as a superconducting logic or detector element) can be performed with a forward-biased optical modulator that is directly coupled to the cryogenic device without any intervening electrical amplifier. Forward-biasing at cryogenic temperatures enables very high modulation efficiency (1,000-10,000 pm/V) of the optical modulator, and allows for optical modulation with millivolt driving signals and microwatt power dissipation in the cryogenic environment. Modulated optical signals can be coupled out of the cryostat via an optical fiber, reducing the thermal load on the cryostat. Using optical fiber instead of electrical wires can increase the communication bandwidth between the cryogenic environment and room-temperature environment to bandwidth densities as high as Tbps/mm2 using wavelength division multiplexing. Sensitive optical signals having higher robustness to noise and crosstalk, because of their immunity to electromagnetic interference, can be carried by the optical fiber.
FILED Friday, November 06, 2020
APPL NO 17/091905
ART UNIT 2883 — Optics
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/0102 (20130101)
G02F 1/0123 (20130101)
G02F 1/212 (20210101)
G02F 1/2257 (20130101) Original (OR) Class
G02F 2202/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11507054 Behandish et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Palo Alto Research Center Incorporated (Palo Alto, California)
ASSIGNEE(S) Palo Alto Research Center Incorporated (Palo Alto, California)
INVENTOR(S) Morad Behandish (Mountain View, California);  Amir Mirzendehdel (Palo Alto, California);  Saigopal Nelaturi (Mountain View, California)
ABSTRACT The present disclosure is directed to a method and system for hierarchical multi-scale design with the aid of a digital computer. A hierarchical representation of a shape and material distribution is constructed which satisfies a top-level constraint at a top-level of representation. Properties for families of designs at each of the lower levels of representation that satisfy additional constraints link each of the lower levels of representation to at least a next higher level of the representation.
FILED Monday, December 31, 2018
APPL NO 16/236949
ART UNIT 2148 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 50/00 (20141201)

Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 19/4099 (20130101) Original (OR) Class
G05B 2219/35012 (20130101)
G05B 2219/49007 (20130101)

Electric Digital Data Processing
G06F 30/20 (20200101)
G06F 30/23 (20200101)
G06F 2111/04 (20200101)
G06F 2111/06 (20200101)
G06F 2119/18 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11507080 Sahay et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut)
ASSIGNEE(S) SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut)
INVENTOR(S) Prateek Sahay (Acton, Massachusetts);  Margaret MacIsaac Lampazzi (Oxford, Connecticut);  Sacha Duff (Shelton, Connecticut)
ABSTRACT A portable computerized device for an aircraft control system includes an input system for inputting commands, a device display for displaying information on the computerized device, a processor, a wireless communication module, and a non-transitory computer readable medium comprising computer executable instructions, the computer executable instructions configured to cause the processor to perform a method. The method can include detecting whether the portable computerized device is in a cockpit state such that the portable computerized device is in and/or docked to an aircraft cockpit or if the portable computerized device is in a remote state such that the portable computerized device is not in an aircraft cockpit or is not docked to an aircraft cockpit. If the portable computerized device is determined to be in a remote state, the method includes operating the remote device in a remote mode. If the portable computerized device is determined to be in a cockpit state, the method includes operating the device in a local mode.
FILED Tuesday, September 19, 2017
APPL NO 16/648017
ART UNIT 3666 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Aeroplanes; Helicopters
B64C 39/024 (20130101)
B64C 2201/12 (20130101)
B64C 2201/146 (20130101)

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 43/00 (20130101)
B64D 45/00 (20130101)

Systems for Controlling or Regulating Non-electric Variables
G05D 1/0016 (20130101) Original (OR) Class
G05D 1/0022 (20130101)

Traffic Control Systems
G08G 5/0004 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11507676 Eldefrawy et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Naval Information Warfare Center Pacific (NIWCPACIFIC)
APPLICANT(S) SRI International (Menlo Park, California)
ASSIGNEE(S) SRI International (Menlo Park, California)
INVENTOR(S) Karim Eldefrawy (Palo Alto, California);  Tancrède Lepoint (New York, New York)
ABSTRACT Systems and methods for selectively sharing of portion of unstructured data containers/documents based on security attributes or policies used to encrypt/decrypt data within the unstructured data containers using standard encryption schemes are provided herein. In some embodiments, a system includes a key generation authority to generate encryption keys based on a selected cryptographic security scheme and one or more security attributes or security policies; an encryption service to selectively encrypt one or more data subgroups using the one or more public keys and based on one or more security attributes or security policies assigned to the one or more data subgroups with the unstructured data containers; and a decryption service to decrypt the one or more data subgroups within unstructured data containers using the one or more secret keys and the one or more public keys.
FILED Wednesday, November 11, 2020
APPL NO 17/095324
ART UNIT 2498 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 16/31 (20190101)
G06F 21/62 (20130101) Original (OR) Class
G06F 21/602 (20130101)
G06F 21/6218 (20130101)
G06F 2221/2107 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/14 (20130101)
H04L 9/088 (20130101)
H04L 9/0618 (20130101)
H04L 9/0819 (20130101)
H04L 9/0861 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11507785 Glassman
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
ASSIGNEE(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S) Martin S. Glassman (Nashua, New Hampshire)
ABSTRACT A classifier network has at least two distinct sets of refined data, wherein the first two sets of refined data are sets of numbers representing the features values data received from sensors or a manufactured part. Performing, via at least two distinct types of support vector machines using an associated feature selection process for each classifier independently in a first layer, anomaly detection on the manufactured part. Then, using the stored data including refined data of at least two different types of data transforms and performing, via at least a two distinct types of support vector machines in a second layer, an associated feature selection process for each classifier independently. Forming at least four distinct compound classifier types for anomaly detection on the part using the stored data or coefficients. The ensemble of second layer support vector machine outputs compare the results to determine the presence of an anomaly.
FILED Thursday, April 30, 2020
APPL NO 16/862867
ART UNIT 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/6228 (20130101)
G06K 9/6232 (20130101)
G06K 9/6262 (20130101)
G06K 9/6269 (20130101) Original (OR) Class
G06K 9/6289 (20130101)

Computer Systems Based on Specific Computational Models
G06N 20/10 (20190101)
G06N 20/20 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11508438 Stellari et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Under Secretary of Defense for Acquisition and Sustainment (USDA&S)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Franco Stellari (Waldwick, New Jersey);  Takashi Ando (Eastchester, New York);  Cyril Cabral, Jr. (Yorktown Heights, New York);  Eduard Albert Cartier (New York, New York);  Martin Michael Frank (Dobbs Ferry, New York);  Peilin Song (Lagrangeville, New York);  Dirk Pfeiffer (Croton on Hudson, New York)
ABSTRACT Methods and systems for locating a filament in a resistive memory device are described. In an example, a device can acquire an image indicating an occurrence of photoemission from the resistive memory device. The device can determine a location of the filament in a switching medium of the resistive memory device using the acquired image.
FILED Friday, October 16, 2020
APPL NO 17/072810
ART UNIT 2825 — Semiconductors/Memory
CURRENT CPC
Static Stores
G11C 13/0069 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11508857 Shen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S) Haoting Shen (Tallahassee, Florida);  Navid Asadizanjani (Gainesville, Florida);  Domenic J. Forte (Gainesville, Florida);  Mark M. Tehranipoor (Gainesville, Florida)
ABSTRACT A pyramid structure to mitigate optical probing attacks in ICs by scrambling the measurements reflected by a laser pulse is disclosed. The pyramid structure is applied to selected areas at the bottom surface of the metal traces in metal layer to circumvent the extra silicon layer and thus minimize the changes to the conventional device structures. The pyramid structure includes randomized pyramids at nanometer scale. Optical simulation results show the pyramidized metal surface is able to prevent optical probing attacks. The fabrication of pyramids is CMOS compatible as well. Optical simulations are performed to analyze the impact these nano-scaled pyramids in a laser voltage probing attacking model. The nanopyramid can disturb the optical measurements enough to make the attacks practically infeasible. In addition, the nanopyramid structure countermeasure works in a passive mode without consuming any energy.
FILED Tuesday, January 28, 2020
APPL NO 16/775178
ART UNIT 2897 — Semiconductors/Memory
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/311 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/76807 (20130101)
H01L 23/53238 (20130101)
H01L 24/05 (20130101)
H01L 31/02363 (20130101) Original (OR) Class
H01L 2924/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11508869 Krishna et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Ohio State Innovation Foundation (Columbus, Ohio)
ASSIGNEE(S) Ohio State Innovation Foundation (Columbus, Ohio)
INVENTOR(S) Sanjay Krishna (Plain City, Ohio);  Sri Harsha Kodati (Columbus, Ohio);  Theodore Ronningen (Lewis Center, Ohio);  Seunghyun Lee (Columbus, Ohio)
ABSTRACT A lateral interband Type II engineered (LITE) detector is provided. LITE detectors use engineered heterostructures to spatially separate electrons and holes into separate layers. The device may have two configurations, a positive intrinsic (PIN) configuration and a BJT (Bipolar junction transistor) configuration. The PIN configuration may have a wide bandgap (WBG) layer that transports the holes above a narrow bandgap (NBG) absorber layer that absorbs the target radiation and transports the electrons. The BJT configuration may have a WBG layer operating as a BJT above an NBG layer. In both configurations, the LITE design uses a Type II staggered offset between the NBG layers and the WBG layers that provides a built-in field for the holes to drift from an absorber region to a transporter region.
FILED Thursday, August 06, 2020
APPL NO 16/986758
ART UNIT 2812 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/109 (20130101) Original (OR) Class
H01L 31/1105 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11508951 Ban et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  The Regents of the University of Colorado, a body corporate (Denver, Colorado)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  The Regents of the University of Colorado, a Body Corporate (Denver, Colorado)
INVENTOR(S) Chunmei Ban (Golden, Colorado);  Simon Elnicki Hafner (Palo Alto, California);  Se-Hee Lee (Superior, Colorado)
ABSTRACT An aspect of the present disclosure is a system that includes a first deposition system that includes a first cylinder having a first outer surface configured to hold a first substrate, a first spray nozzle configured to receive at least a first fluid, and a first fiber nozzle configured to receive at least a second fluid, where the first spray nozzle is configured to operate at a first voltage, the first fiber nozzle is configured to operate at a second voltage, the first cylinder is configured to be electrically connected to ground, the first spray nozzle is configured to apply onto the substrate a first plurality of at least one of particles or droplets from the first fluid, the first fiber nozzle is configured to apply onto the substrate a first fiber from the second fluid, and the first plurality of particles or droplets and the first fiber combine to form a first composite layer on the substrate.
FILED Wednesday, November 13, 2019
APPL NO 16/682064
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/043 (20130101)
H01M 4/131 (20130101)
H01M 4/0404 (20130101)
H01M 4/0407 (20130101)
H01M 4/0409 (20130101)
H01M 4/0419 (20130101) Original (OR) Class
H01M 4/1391 (20130101)
H01M 10/0525 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11508968 Belcher et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Angela Belcher (Lexington, Massachusetts);  Jifa Qi (West Roxbury, Massachusetts);  Geran Zhang (Cambridge, Massachusetts)
ABSTRACT A composition can include a carbon nanofiber, wherein a precursor for the carbon nanofiber includes an alcohol and an aldehyde crosslinked by a primary amine. In certain embodiments, the carbon nanofiber can be biotemplated. Biotemplating enables precise control of morphology at the nanometer scale, while molecular templating allows control of carbon nanotexture and structure at the sub-nanometer scale.
FILED Friday, February 15, 2019
APPL NO 16/278041
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/158 (20170801)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2795/14031 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/663 (20130101) Original (OR) Class
H01M 10/052 (20130101)
H01M 2004/028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11509451 Pham
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Khanh Pham (Albuquerque, New Mexico)
ABSTRACT The present disclosure provides an analytical framework to investigate judicious topology reweighting of radio networks of clocks, when distributed time transfer and synchronization are based on physical layers and subject to the presence of false timing signals. Protagonist clocks exchange timing information pairwise, which is modeled as clocks tending to follow the majority of their neighbors. Antagonist clocks inject false timing signals, thereby, influencing the timing synchronization of (some of) the other protagonist clocks they meet. A class of pursuit-evasion graphical games subject to complete state observations and exploitation of phase noise disturbances, is proposed in designing clock steering protocols for resilient time metrologies that will be immune to erroneous timing signals injected into remote time dissemination networks.
FILED Thursday, February 25, 2021
APPL NO 17/185110
ART UNIT 2412 — Multiplex and VoIP
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 7/0331 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11509683 Vela et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Booz Allen Hamilton Inc. (McLean, Virginia)
ASSIGNEE(S) BOOZ ALLEN HAMILTON INC. (McLean, Virginia)
INVENTOR(S) Chelsea Vela (San Antonio, Texas);  Justin Hoffman (Boerne, Texas)
ABSTRACT A system for generating a cyber-attack to penetrate a network. The system includes an identification module configured to identify at least one vulnerability of the network by examining at least one of a node of the network, data transmission within the network, or data received from a cyber defense mechanism; a generation module configured to generate a cyber-attack based on the at least one vulnerability of the network, and a goal to be achieved by the cyber-attack. The system includes a penetration module configured to penetrate the network with the cyber-attack and determine an effectiveness rating of the penetration; and a feedback module configured to provide a feedback to the identification module based on at least the effectiveness rating of the penetration.
FILED Friday, January 14, 2022
APPL NO 17/575917
ART UNIT 2496 — Multiplex and VoIP
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/1416 (20130101)
H04L 63/1433 (20130101) Original (OR) Class
H04L 63/1466 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11510148 Bulsara et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Information Warfare Center (NIWC)
Naval Information Warfare Center Pacific (NIWCPACIFIC)
APPLICANT(S) Naval Information Warfare Center Pacific (San Diego, California)
ASSIGNEE(S) United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Adi Ratan Bulsara (San Diego, California);  Bruno Ando (Catania, Italy);  Salvatore Baglio (Catania, Italy);  Vincenzo Marletta (Catania, Italy)
ABSTRACT An autonomous sensor that includes a snap-through buckling beam, a proof mass, an ultra-low-power microcontroller unit, a wireless transmitter, a power management unit, and a power storage unit. The snap-through buckling beam produces mechanical energy. The proof mass is attached to the snap-through buckling beam. The proof mass transfers mechanical energy to two piezoelectric transducers that convert the mechanical energy into electrical energy and produce an output signal. The ultra-low-power microcontroller unit converts the output signal into output data. The wireless transmitter transfers the output data to an external device. The power management unit provides the electrical energy to the ultra-low-power microcontroller unit and the wireless transmitter. The power storage unit is rechargeable, stores electrical energy from the two piezoelectric transducers, and non-replaceable. The autonomous sensor simultaneously harvests energy and measures vibrations in an external environment.
FILED Tuesday, December 01, 2020
APPL NO 17/108503
ART UNIT 2645 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for
F03G 7/08 (20130101)

Wireless Communication Networks
H04W 52/0229 (20130101)
H04W 52/0254 (20130101) Original (OR) Class
H04W 84/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE49304 Gao et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
APPLICANT(S) University of Washington through its Center for Commercialization (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Xiaohu Gao (Shoreline, Washington);  Pavel Zrazhevskiy (Redmond, Washington)
ABSTRACT Provided herein are compositions and methods for identifying or quantitating one or more analytes in sample. The composition can comprise an affinity molecule reversibly conjugated to a label moiety via a double-stranded nucleic acid linker or via an adaptor molecule. The affinity molecule and the label moiety can be linked to different strands of the double-stranded nucleic acid linker. Compositions can be used in any biological assays for detection, identification and/or quantification of target molecules or analytes, including multiplex staining for molecular profiling of individual cells or cellular populations. For example, the compositions can be adapted for use in immunofluorescence, fluorescence in situ hybridization, immunohistochemistry, western blot, and the like.
FILED Friday, April 03, 2020
APPL NO 16/840107
ART UNIT 3991 — Central Reexamination Unit (Chemical)
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6804 (20130101)
C12Q 1/6804 (20130101)
C12Q 1/6841 (20130101) Original (OR) Class
C12Q 2563/155 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/587 (20130101)
G01N 33/588 (20130101)
G01N 2458/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 11504286 Cooper et al.
FUNDED BY
Department of Veterans Affairs (DVA)
National Science Foundation (NSF)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia);  FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (Munich, Germany)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia);  FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (Munich, Germany)
INVENTOR(S) Rory Alan Cooper (Gibsonia, Pennsylvania);  Hongwu Wang (Edmond, Oklahoma);  Brandon Joseph Daveler (Pittsburgh, Pennsylvania);  Benjamin Todd Gebrosky (Gibsonia, Pennsylvania);  Garrett G. Grindle (Pittsburgh, Pennsylvania);  Jonathan L. Pearlman (Pittsburgh, Pennsylvania);  Urs Schneider (Stuttgart, Germany);  David Minzenmay (Stuttgart, Germany)
ABSTRACT A personal mobility device includes a frame, a plurality of wheels attached to the frame and one or more pneumatic motors. Each of the one or more pneumatic motors has a drive shaft in operative connection with at least one of the plurality of wheels. The personal mobility device further includes at least one tank (that is, a storage container) for storage of a pressurized gas in operative connection with the one or more pneumatic motors to supply pressurized gas to the one or more pneumatic motors and a control system in operative connection with the at least one tank and with the one or more pneumatic motors.
FILED Wednesday, January 04, 2017
APPL NO 16/067992
ART UNIT 3611 — Material and Article Handling
CURRENT CPC
Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices
A61G 5/04 (20130101) Original (OR) Class
A61G 5/10 (20130101)
A61G 5/045 (20130101)
A61G 5/048 (20161101)
A61G 5/1051 (20161101)

Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles
B60K 7/0023 (20130101)
B60K 2007/0038 (20130101)
B60K 2007/0092 (20130101)

Indexing Scheme Relating to Aspects Cross-cutting Vehicle Technology
B60Y 2200/13 (20130101)
B60Y 2200/84 (20130101)
B60Y 2200/126 (20130101)

Positive-displacement Engines Driven by Liquids
F03C 2/00 (20130101)

Gearing
F16H 7/06 (20130101)
F16H 48/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504325 Polt et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
INVENTOR(S) Robin L. Polt (Tucson, Arizona);  Dillon Hanrahan (Tucson, Arizona);  Lajos Z. Szabo (Tucson, Arizona);  Michael L. Heien (Tucson, Arizona);  Chenxi Liu (Tucson, Arizona)
ABSTRACT Methods for quality control and optimizing the formation and characterization of micelles, vesicles or other aggregates are described herein. Pharmaceutically relevant peptides may be modified to form glycopeptide surfactants which form micelles or other aggregates with another surfactant. Glycopeptide and glycolipid surfactants can aggregate to form particles that enhance drug delivery. The glycopeptide surfactants may be drugs or pro-drugs which are delivered via the micelles or other aggregated structures.
FILED Thursday, August 09, 2018
APPL NO 16/637671
ART UNIT 1699 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/107 (20130101) Original (OR) Class
A61K 38/018 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504335 Gottipati et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) University of Kentucky Research Foundation (Lexington, Kentucky)
ASSIGNEE(S) University of Kentucky Research Foundation (Lexington, Kentucky)
INVENTOR(S) Anuhya Gottipati (Lexington, Kentucky);  Irina Kalashnikova (Lexington, Kentucky);  Ahmed Abdel-Latif (Lexington, Kentucky);  Bradley J. Berron (Lexington, Kentucky)
ABSTRACT The presently-disclosed subject matter relates to compositions of dual layer encapsulated cells, dual layer encapsulated stem cells. The presently-disclosed subject matter further relates to methods for improving retention of cells in vivo at a site of injury.
FILED Tuesday, June 18, 2019
APPL NO 16/445046
ART UNIT 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/4825 (20130101) Original (OR) Class
A61K 35/28 (20130101)
A61K 35/44 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/10 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504425 Liu et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) WAYNE STATE UNIVERSITY (Detroit, Michigan)
ASSIGNEE(S) Wayne State University (Detroit, Michigan)
INVENTOR(S) Haipeng Liu (Troy, Michigan);  Chunsong Yu (Detroit, Michigan)
ABSTRACT Amphiphilic oligonucleotide conjugates that enhance adjuvant function are disclosed. The conjugates typically include: a lipophilic component, and conjugated thereto (directly or indirectly) an immunomodulating oligonucleotide that, if it were not conjugated to the lipophilic component, would suppress TLR7 and/or TLR8 stimulation. In the presence of albumin, these conjugates significantly enhance adjuvant function, in particular the function of TLR7/8-mediated adjuvants such as an imidazoquinolinamine. The conjugates can be administered, along with an adjuvant compound, to a subject in order to cause and/or enhance an immune response (for instance, to an infectious agent or a cancer antigen) in the subject.
FILED Thursday, February 20, 2020
APPL NO 16/795953
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/39 (20130101) Original (OR) Class
A61K 47/543 (20170801)
A61K 47/549 (20170801)
A61K 47/554 (20170801)
A61K 2039/575 (20130101)
A61K 2039/55511 (20130101)
A61K 2039/55561 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/117 (20130101)
C12N 2310/17 (20130101)
C12N 2310/315 (20130101)
C12N 2310/3515 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504434 Yang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania)
ASSIGNEE(S) The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S) Jian Yang (State College, Pennsylvania);  Cheng Dong (State College, Pennsylvania);  Zhiwei Xie (State College, Pennsylvania)
ABSTRACT In one aspect, methods of targeted nanoparticles and cell delivery are described herein. In some embodiments methods described herein comprise coupling nanoparticles and cells to a carrier cell to form a nanoparticle-cell conjugate or cell-cell conjugate, disposing the nanoparticle-cell or cell-cell conjugate in a biological environment, and delivering the nanoparticles and cells to target cells or tissues located within the biological environment. The nanoparticles comprise a biodegradable photoluminescent polymer, and the nanoparticle-cell conjugate is formed using one or more click chemistry reaction products.
FILED Monday, January 06, 2020
APPL NO 16/734816
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5153 (20130101)
A61K 31/337 (20130101)
A61K 31/437 (20130101)
A61K 47/62 (20170801)
A61K 47/65 (20170801)
A61K 47/593 (20170801)
A61K 47/6901 (20170801) Original (OR) Class
A61K 47/6937 (20170801)
A61K 49/0093 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505467 Jeon et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Intak Jeon (Boston, Massachusetts);  Timothy M. Swager (Newton, Massachusetts)
ABSTRACT Carbon-based materials, and associated methods and articles, are generally provided. In some embodiments, a carbon-based material comprises a carbon-based portion and a functional group bonded to the carbon-based portion. The functional group may be capable of forming a reversible covalent bond with a species. Carbon may make up greater than or equal to 30 wt % of the carbon-based portion. The carbon-based portion may comprise graphene, and a ratio of a total number of functional groups in a plurality of functional groups bonded to the graphene to a total number of carbon atoms in the plurality of carbon atoms of the graphene may be greater than or equal to 1:50. The carbon-based portion may comprise graphene, and greater than or equal to 70% of the graphene sheets may be spaced apart from their nearest neighbors by a distance of greater than or equal to 10 Å. A method may comprise applying a voltage to a carbon-based material. The voltage may be applied in the presence of a combination of solvents comprising a dissolved species. The combination of solvents may comprise a solvent stable at voltages of greater than or equal to −3.15 V and less than or equal to −2.2 V and/or may comprise a solvent with a surface tension within 25% of a surface tension of the carbon-based material. The voltage may be a decreasing voltage that decreases at a rate of greater than or equal to 2 μV/s and less than or equal to 40 μV/s and has a value of greater than or equal to −2.2 V and less than or equal to −3.15 V at at least one point in time.
FILED Tuesday, November 06, 2018
APPL NO 16/182371
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/21 (20170801)
C01B 32/194 (20170801)
C01B 32/225 (20170801) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/3271 (20130101)
G01N 33/5306 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505877 Liu et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Chunghorng Liu (West Lafayette, Indiana);  Siyu Liu (West Lafayette, Indiana)
ABSTRACT A method of selectively controlling materials structure in solution based chemical synthesis and deposition of materials by controlling input energy from pulsed energy source includes determining solution conditions, searching and/or determining energy barrier(s) of a desired materials structure formation, applying precursor solution with selected solution condition onto a substrate, and applying determined input energy from a pulsed energy source with a selected condition to the substrate, thereby nucleating and growing the crystal.
FILED Friday, November 29, 2019
APPL NO 16/699459
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 25/16 (20130101) Original (OR) Class
C30B 29/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11506553 Dong et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
ASSIGNEE(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
INVENTOR(S) Liang Dong (Ames, Iowa);  Qiugu Wang (Ames, Iowa);  Wei Hong (Ames, Iowa)
ABSTRACT We present a microelectromechanical system (MEMS) graphene-based pressure sensor realized by transferring a large area, few-layered graphene on a suspended silicon nitride thin membrane perforated by a periodic array of micro-through-holes. Each through-hole is covered by a circular drum-like graphene layer, namely a graphene “microdrum”. The uniqueness of the sensor design is the fact that introducing the through-hole arrays into the supporting nitride membrane allows generating an increased strain in the graphene membrane over the through-hole array by local deformations of the holes under an applied differential pressure. Further reasons contributing to the increased strain in the devised sensitive membrane include larger deflection of the membrane than that of its imperforated counterpart membrane, and direct bulging of the graphene microdrum under an applied pressure. Electromechanical measurements show a gauge factor of 4.4 for the graphene membrane and a sensitivity of 2.8×10-5 mbar-1 for the pressure sensor specific example described, with a good linearity over a wide pressure range. The present sensor outperforms most existing MEMS-based small footprint pressure sensors using graphene, silicon, and carbon nanotubes as sensitive materials, due to the high sensitivity.
FILED Monday, September 21, 2020
APPL NO 16/948475
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 9/0047 (20130101)
G01L 9/0054 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11506592 Javanmard et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
National Science Foundation (NSF)
APPLICANT(S) Rutgers, the State University of New Jersey (New Brunswick, New Jersey)
ASSIGNEE(S) Rutgers, the State University of New Jersey (New Brunswick, New Jersey)
INVENTOR(S) Mehdi Javanmard (West Windsor, New Jersey);  Abbas Furniturewalla (Collegeville, Florida)
ABSTRACT This disclosure provides an impedance cytometer which includes a carrier that can be attached to a living being, with a biosensor mounted thereto. The bio sensor includes a microfluidic flow channel, formed in the carrier, and an impedance circuit. The microfluidic flow channel accommodates passage of a particle therethrough. The impedance circuit, connected to the microfluidic flow channel, includes a signal generator that produces a high-frequency drive signal applied to the flow channel to produce a biosensor output signal having high-frequency variation resulting from the drive signal and low-frequency variation resulting from impedance variation within the flow channel during the particle's passage. A lock-in amplifier is disposed to (i) amplify the bio sensor output signal, (ii) mix the amplified signal with the drive signal, and (iii) frequency-filter the mixed, amplified signal to output an impedance signal representing the low-frequency impedance variation resulting from the passage of the particle. Embodiments enable wearable, personalized cytometry.
FILED Thursday, October 17, 2019
APPL NO 16/656148
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/02 (20130101)
G01N 15/1209 (20130101)
G01N 15/1404 (20130101) Original (OR) Class
G01N 33/4836 (20130101)
G01N 2015/008 (20130101)
G01N 2015/0073 (20130101)
G01N 2015/1006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11506602 Escarra et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (New Orleans, Louisiana)
ASSIGNEE(S) THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (New Orleans, Louisiana)
INVENTOR(S) Matthew David Escarra (New Orleans, Louisiana);  Adam Ollanik (Boulder, Colorado)
ABSTRACT A method for measuring a refractive index of a medium includes exciting a first antisymmetric resonance of a first metasurface, including a first periodic array of resonators formed on a substrate surface, with illumination incident on the first metasurface at a non-normal incidence angle with respect to the substrate surface, the first metasurface including the medium encapsulating the first periodic array of resonators. The method also includes determining a refractive index of the medium from a first amplitude of a first transmitted signal that includes a portion of the illumination transmitted through the first metasurface.
FILED Monday, May 13, 2019
APPL NO 17/055833
ART UNIT 2886 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/4133 (20130101) Original (OR) Class

Optical Elements, Systems, or Apparatus
G02B 1/002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11506606 Bedell et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) SweetSense, Inc. (Denver, Colorado)
ASSIGNEE(S) SWEETSENSE, INC. (Denver, Colorado)
INVENTOR(S) Emily Bedell (Denver, Colorado);  Katie Frankhauser (Denver, Colorado);  Taylor Sharpe (Denver, Colorado);  Daniel Wilson (Denver, Colorado);  Evan Thomas (Denver, Colorado)
ABSTRACT In-situ fluorimeters and methods and systems for collecting and analyzing sensor data to predict water source contamination are provided. In one embodiment, a method is provided that includes receiving sensor data regarding a water source. Changepoints may then be calculated within the sensor data and the sensor data may be split into intervals at the changepoints. A machine learning model may then be used to classify the intervals and a predicted contamination event for the water source may be identified based on the classified intervals. In another embodiment, an in-situ fluorimeter is provided. The in-situ fluorimeter comprises one or more UV LEDs centered around a pre-set excitation wavelength (e.g., a TLF excitation wavelength), a bandpass filter, a lens, a photodiode system, a machine learning platform; and an alarm triggered by contamination events, wherein the alarm is calibrated through the machine learning system.
FILED Friday, February 28, 2020
APPL NO 16/804605
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/85 (20130101)
G01N 21/643 (20130101)
G01N 21/645 (20130101)
G01N 21/6456 (20130101) Original (OR) Class
G01N 33/1826 (20130101)
G01N 2021/6467 (20130101)
G01N 2201/062 (20130101)
G01N 2201/126 (20130101)
G01N 2201/0626 (20130101)

Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 13/00 (20130101)

Computer Systems Based on Specific Computational Models
G06N 5/04 (20130101)
G06N 20/00 (20190101)

Signalling or Calling Systems; Order Telegraphs; Alarm Systems
G08B 21/18 (20130101)
G08B 29/26 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11506619 Alexeenko et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Alina Alexeenko (West Lafayette, Indiana);  Andrew Strongrich (Saginaw, Michigan)
ABSTRACT A microelectromechanical (MEMS) gas sensor operating based on Knudsen thermal force is disclosed. The sensor includes a substrate, at least one stationary assembly that is fixedly coupled to the substrate, and at least one moveable assembly that is positioned above the substrate which is biased to move substantially according to a main axis and juxtaposed with the at least one stationary assembly.
FILED Wednesday, December 26, 2018
APPL NO 16/233023
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 25/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11506841 Ramachandran et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
Office of Science (DOE-SC)
Brookhaven National Laboratory (BNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Brookhaven Science Associates, LLC (BSA) at Upton, NY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Trustees of Boston University (Boston, Massachusetts)
ASSIGNEE(S) Trustees of Boston University (Boston, Massachusetts)
INVENTOR(S) Siddharth Ramachandran (Boston, Massachusetts);  Zelin Ma (Boston, Massachusetts)
ABSTRACT An optical fiber system exploits a principle of topological confinement for guided higher-order modes, in contrast to more conventional total-internal-reflection (TIR) confinement. The optical fiber has a geometry and index profile defining a cutoff wavelength for a predetermined L-mode of optical signal propagation in the optical fiber, where L is azimuthal mode index. An optical source subsystem is coupled to the optical fiber to establish an optical signal propagating in the optical fiber, wherein the optical signal has the predetermined L-mode and a wavelength being either (1) at least 15% above the cutoff wavelength such that the optical beam propagates as a topologically confined mode, or (2) sufficiently above the cutoff wavelength that, based on the L-mode of the optical beam, the optical beam propagates as a topologically confined mode having propagation loss less than 3 dB/meter.
FILED Sunday, May 09, 2021
APPL NO 17/315314
ART UNIT 2883 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/14 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11507041 Sarwat et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Arif I. Sarwat (Miami, Florida);  Temitayo O. Olowu (Miami, Florida);  Shamini Dharmasena (Miami, Florida)
ASSIGNEE(S) THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S) Arif I. Sarwat (Miami, Florida);  Temitayo O. Olowu (Miami, Florida);  Shamini Dharmasena (Miami, Florida)
ABSTRACT Systems and methods for boosting resiliency of a power distribution network (PDN) are provided. A distributed energy resource (DER) hosting process can be used to boost network resiliency through the use of locally installed DER systems that can be operated, dispatched, and/or controlled as individual power plants. A unique critical infrastructure (CI) ranking scheme can be used to prioritize CIs to be optimally located close to the DER while increasing the DER hosting capacity of the network.
FILED Tuesday, May 03, 2022
APPL NO 17/661789
ART UNIT 2119 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 19/042 (20130101) Original (OR) Class
G05B 2219/2639 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 3/381 (20130101)
H02J 2300/24 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11507861 Wilson et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) SweetSense, Inc. (Denver, Colorado)
ASSIGNEE(S) SWEETSENSE, INC. (Denver, Colorado)
INVENTOR(S) Daniel Wilson (Denver, Colorado);  Jeremy Coyle (Denver, Colorado);  Evan Thomas (Denver, Colorado);  Skot Croshere (Denver, Colorado)
ABSTRACT Methods and systems for collecting and analyzing sensor data to predict water fixture failure and water consumption are provided. In one embodiment, a method is provided that includes receiving sensor data regarding a water fixture. Changepoints may then be calculated within the sensor data and the sensor data may be split into intervals at the changepoints. A machine learning model may then be used to classify the intervals and a status of the water fixture and water consumption may be identified based on the classified intervals.
FILED Wednesday, February 26, 2020
APPL NO 16/801722
ART UNIT 2473 — Multiplex and VoIP
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 5/04 (20130101) Original (OR) Class
G06N 20/00 (20190101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/20 (20130101)
G06Q 50/06 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/12 (20130101)

Selecting
H04Q 9/00 (20130101)
H04Q 2209/10 (20130101)
H04Q 2209/70 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11508346 Shelton et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) Invensense, Inc. (San Jose, California)
ASSIGNEE(S) InvenSense, Inc. (San Jose, California)
INVENTOR(S) Stefon Shelton (Berkeley, California);  Andre Guedes (Berkeley, California);  David Horsley (Berkeley, California)
ABSTRACT A package design for a micromachined ultrasound transducer (MUT) utilizing curved geometry to control the presence and frequency of acoustic resonant modes is described. The approach consists of reducing in number and curving the reflecting surfaces present in the package cavity to adjust the acoustic resonant frequencies to locations outside the band of interest. The design includes a cavity characterized by a curved geometry and a MUT mounted to a side of a substrate facing the cavity with a sound emitting portion of the MUT facing an opening in the substrate. The substrate is disposed over an opening of the cavity with the substrate oriented such that the MUT located within the cavity.
FILED Wednesday, May 23, 2018
APPL NO 15/987824
ART UNIT 2689 — Signal Processing and Control Processing in Disk Drives
CURRENT CPC
Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for
G10K 9/22 (20130101) Original (OR) Class
G10K 9/122 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11508911 Kosco et al.
FUNDED BY
National Science Foundation (NSF)
Office of Sponsored Research (OSR)
APPLICANT(S) KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (Thuwal, Saudi Arabia);  IMPERIAL COLLEGE (London, United Kingdom)
ASSIGNEE(S) KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (Thuwal, Saudi Arabia);  IMPERIAL COLLEGE LONDON (London, United Kingdom)
INVENTOR(S) Jan Kosco (Thuwal, Saudi Arabia);  Matthew Bidwell (London, United Kingdom);  Hyojung Cha (London, United Kingdom);  Calvyn T. Howells (Thuwal, Saudi Arabia);  James R. Durrant (London, United Kingdom);  Iain McCulloch (Thuwal, Saudi Arabia)
ABSTRACT A nanoparticle comprises an internal D/A heterojunction, wherein the nanoparticle comprises a HER rate of 64,426±7022 μmolh−1g−1 under broadband visible light illumination. Measured EQEs of the nanoparticle throughout a visible spectrum exceed 5% at 660 to 700 nm. Methods may include fabricating a nanoparticle comprising: preparing individual stock solutions of PTB7-TH and EH-IDTBR in chloroform; heating the individual stock solutions to a complete dissolution; filtering the individual stock solutions; preparing a nanoparticle precursor solution from the filtered individual stock solutions by mixing the individual stock solutions in a ratio of 0-100% EH-IDTBR adding a portion of the nanoparticle precursor solution to a solution of surfactant (SDS or TEBS) in water and mixing to form a pre-emulsion; sonicating the pre-emulsion to form a mini-emulsion; heating the mini-emulsion to remove the chloroform to thereby form a surfactant stabilized nanoparticle dispersion; and filtering the nanoparticle.
FILED Friday, September 11, 2020
APPL NO 17/639966
ART UNIT 2897 — Semiconductors/Memory
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 23/42 (20130101)
B01J 35/0013 (20130101)
B01J 37/344 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 20/00 (20130101)
B82Y 40/00 (20130101)

Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 1/02 (20130101)
C25B 1/55 (20210101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 51/0036 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11508917 Claridge et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Shelley A. Claridge (Lafayette, Indiana);  Tyler Hayes (Lafayette, Indiana);  David McMillan (Lafayette, Indiana)
ABSTRACT This invention generally relates to a method for preparing and transferring a monolayer or thin film. In particular this present invention is an improved version of the Langmuir-Schaefer technique for preparing and transferring a monolayer or thin film, incorporating in situ thermal control of the substrate during the transfer process.
FILED Thursday, June 18, 2020
APPL NO 16/904716
ART UNIT 1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Processes for Applying Fluent Materials to Surfaces, in General
B05D 1/204 (20130101)
B05D 1/208 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 51/0012 (20130101)
H01L 51/0026 (20130101)
H01L 51/0075 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11509365 Karabacak et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) University of South Florida (Tampa, Florida)
ASSIGNEE(S) University of South Florida (Tampa, Florida)
INVENTOR(S) Murat Karabacak (Tampa, Florida);  Liza Afeef (Istanbul, Turkey);  Huseyin Arslan (Tampa, Florida)
ABSTRACT A system and method utilizing a novel dynamic sidelobe multiplexing (DSM) is proposed for the applications in beamspace multiple-input multiple-output (MIMO) systems. The DSM technique pre-codes the transmitted data over transmitter beams in order to open up a new path to the receiver.
FILED Tuesday, December 14, 2021
APPL NO 17/550576
ART UNIT 2631 — Digital Communications
CURRENT CPC
Transmission
H04B 7/0456 (20130101) Original (OR) Class
H04B 7/0697 (20130101)
H04B 17/336 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE49304 Gao et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
APPLICANT(S) University of Washington through its Center for Commercialization (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Xiaohu Gao (Shoreline, Washington);  Pavel Zrazhevskiy (Redmond, Washington)
ABSTRACT Provided herein are compositions and methods for identifying or quantitating one or more analytes in sample. The composition can comprise an affinity molecule reversibly conjugated to a label moiety via a double-stranded nucleic acid linker or via an adaptor molecule. The affinity molecule and the label moiety can be linked to different strands of the double-stranded nucleic acid linker. Compositions can be used in any biological assays for detection, identification and/or quantification of target molecules or analytes, including multiplex staining for molecular profiling of individual cells or cellular populations. For example, the compositions can be adapted for use in immunofluorescence, fluorescence in situ hybridization, immunohistochemistry, western blot, and the like.
FILED Friday, April 03, 2020
APPL NO 16/840107
ART UNIT 3991 — Central Reexamination Unit (Chemical)
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6804 (20130101)
C12Q 1/6804 (20130101)
C12Q 1/6841 (20130101) Original (OR) Class
C12Q 2563/155 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/587 (20130101)
G01N 33/588 (20130101)
G01N 2458/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 11504640 Boyson
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Kansas City National Security Campus (KCNSC)
NNSA Critical Mission Site
Operated by Honeywell Federal Manufacturing and Technologies, LLC (FM&T) at Kansas City, MO
APPLICANT(S) Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
ASSIGNEE(S) Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
INVENTOR(S) Jonathan M. Boyson (Grain Valley, Missouri)
ABSTRACT Systems and methods of detecting launch of a model rocket are described herein. A mechanically implemented launch accelerometer may be disposed on a model rocket. The launch accelerometer may detect acceleration of the rocket by a mass of the launch accelerometer moving relative to the rocket and against a spring force based on the rocket acceleration. The mass may comprise a first electrical contact that may contact a second electrical contact when the mass is accelerated beyond a threshold, which is indicative of launch of the rocket. The contact between the first electrical contact and the second electrical contact may complete an electrical circuit. Furthermore, at least one pin may lock the mass in a position allowing the electrical circuit to remain complete.
FILED Tuesday, July 20, 2021
APPL NO 17/380389
ART UNIT 3711 — Amusement and Education Devices
CURRENT CPC
Toys, e.g Tops, Dolls, Hoops or Building Blocks
A63H 27/005 (20130101) Original (OR) Class
A63H 27/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504692 Lai et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Canhai Lai (Knoxville, Tennessee);  Lonnie J. Love (Knoxville, Tennessee);  James E. Parks, II (Knoxville, Tennessee);  Xin Sun (Knoxville, Tennessee);  Constantinos Tsouris (Oak Ridge, Tennessee);  Michael Matuszewski (Canonsburg, Pennsylvania)
ABSTRACT A packing device for mass and heat transfer with a subject fluid includes a housing having opposing ends, and subject fluid openings at each opposing end defining a subject fluid flow path for at least one subject fluid flowing through the packing device. A plurality of mass and heat transfer plates each include an interior heat exchange fluid channel disposed between interior heat transfer surfaces of the mass and heat transfer plates. A heat exchange fluid inlet and fluid outlet can supply and remove heat exchange fluid to the heat exchange fluid channels of the mass and heat transfer plates. The mass and heat transfer plates can be oriented to define there between fluid flow channels for the subject fluid. A method and system for mass and heat transfer with a subject fluid, and a method and system for the removal of CO2 from a gas stream are disclosed.
FILED Thursday, June 04, 2020
APPL NO 16/892949
ART UNIT 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 53/18 (20130101)
B01D 53/1475 (20130101)
B01D 53/1493 (20130101)
B01D 2252/20484 (20130101)
B01D 2252/20489 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/32 (20130101) Original (OR) Class
B01J 2219/00763 (20130101)
B01J 2219/00873 (20130101)
B01J 2219/3221 (20130101)
B01J 2219/3325 (20130101)
B01J 2219/32275 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504854 Marvi et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S) Hamidreza Marvi (Tempe, Arizona);  Ehsan Dehghan-Niri (Las Cruces, New Mexico);  Mahdi Ilami (Tempe, Arizona)
ASSIGNEE(S) Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona);  Arrowead Center (Las Cruces, New Mexico)
INVENTOR(S) Hamidreza Marvi (Tempe, Arizona);  Ehsan Dehghan-Niri (Las Cruces, New Mexico);  Mahdi Ilami (Tempe, Arizona)
ABSTRACT Various embodiments of a bio-inspired robot operable for detecting crack and corrosion defects in tubular structures are disclosed herein.
FILED Thursday, April 09, 2020
APPL NO 16/844519
ART UNIT 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 9/1664 (20130101)
B25J 9/1694 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505644 Jasti et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) University of Oregon (Eugene, Oregon);  The Johns Hopkins University (Baltimore, Maryland);  Georgetown University (Washington, District of Columbia)
ASSIGNEE(S) University of Oregon (Eugene, Oregon);  Georgetown University (Washington, District of Columbia);  The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Ramesh Jasti (Eugene, Oregon);  Ruth Maust (Eugene, Oregon);  Curtis Colwell (Eugene, Oregon);  John Dayton Tovar (Baltimore, Maryland);  Garvin Peters (Philadelphia, Pennsylvania);  Haley Bates (Orange, California);  Miklos Kertesz (Bethesda, Maryland);  Girishma Grover (Washington, District of Columbia)
ABSTRACT Polymer embodiments comprising nanohoop-containing polymer backbones are described, along with methods of making and using the same. The polymer embodiments exhibit unique radial and linear conjugation and can be used in a variety of devices, such as electronic and/or optoelectronic devices.
FILED Friday, September 25, 2020
APPL NO 17/033458
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 15/14 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 61/10 (20130101)
C08G 61/126 (20130101) Original (OR) Class
C08G 2261/42 (20130101)
C08G 2261/124 (20130101)
C08G 2261/148 (20130101)
C08G 2261/312 (20130101)
C08G 2261/1412 (20130101)
C08G 2261/3229 (20130101)
C08G 2261/3328 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505810 Haushalter et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S) Robert W. Haushalter (Emeryville, California);  Jay D. Keasling (Berkeley, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Robert W. Haushalter (Emeryville, California);  Jay D. Keasling (Berkeley, California)
ABSTRACT This present invention provides for a genetically modified host cell, or a cell-free reaction system, and related methods and materials for the biocatalytic production of an alkyl lactones from a hydroxy fatty acid, or natural alkyl lactones and esters from sugars using non-natural combinations of enzymes.
FILED Thursday, March 05, 2020
APPL NO 16/810655
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/20 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 5/023 (20130101)
C12P 7/24 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505867 Freiderich
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
National Security Complex and PANTEX Plant (Y-12)
NNSA Critical Mission Site
Operated by Consolidated Nuclear Security, LLC at Oak Ridge, TN (CNS)
APPLICANT(S) Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Melissa Ensor Freiderich (Oak Ridge, Tennessee)
ABSTRACT Systems and methods for electroless plating a first metal onto a second metal in a molten salt bath including: a bath vessel holding a dry salt mixture including a dry salt medium and a dry salt medium of the first metal, and without the reductant therein, the dry salt mixture configured to be heated to form a molten salt bath; and the second metal is configured to be disposed in the molten salt bath and receive a pure coating of the first metal thereon by electroless plating in the molten salt bath, wherein the second metal is more electronegative than the first metal.
FILED Monday, June 14, 2021
APPL NO 17/346504
ART UNIT 1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Apparatus for Applying Fluent Materials to Surfaces, in General
B05C 3/02 (20130101)
B05C 3/005 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 18/31 (20130101) Original (OR) Class
C23C 18/1619 (20130101)
C23C 18/1628 (20130101)
C23C 18/1637 (20130101)
C23C 18/1676 (20130101)

Processes for the Electrolytic Removal of Materials From Objects; Apparatus Therefor
C25F 3/02 (20130101)
C25F 7/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11506342 Elgowainy et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UChicago Argonne, LLC (Chicago, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S) Amgad A. Elgowainy (Lisle, Illinois);  Krishna R. Reddi (Bolingbrook, Illinois)
ABSTRACT A method and a precooling system are provided for precooling gaseous fuel supplied for fueling pressurized gaseous vehicle onboard storage tank systems. The precooling system is used in pressurized gaseous fueling stations with source fuels in cryogenic state, such as liquid hydrogen (LH2) and liquefied nature gas (LNG). A thermal buffer heat exchanger includes a heat exchanger medium, and a cold loop and a warm loop contained in the heat exchanger medium. A control unit is configured for controlling cryogenic fuel supplied to the cold loop for cooling the thermal buffer heat exchanger. The thermal buffer heat exchanger enables precooling high pressure gaseous fuel to a preset temperature supplied to a dispenser supplying high pressure gaseous fuel to refuel a vehicle onboard storage tank system.
FILED Thursday, May 20, 2021
APPL NO 17/325819
ART UNIT 3753 — Fluid Handling and Dispensing
CURRENT CPC
Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases
F17C 7/04 (20130101) Original (OR) Class
F17C 2221/012 (20130101)
F17C 2221/033 (20130101)
F17C 2223/0161 (20130101)
F17C 2225/0123 (20130101)
F17C 2227/0135 (20130101)
F17C 2227/0323 (20130101)
F17C 2227/0355 (20130101)
F17C 2250/032 (20130101)
F17C 2250/0636 (20130101)
F17C 2265/065 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11506841 Ramachandran et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
Office of Science (DOE-SC)
Brookhaven National Laboratory (BNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Brookhaven Science Associates, LLC (BSA) at Upton, NY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Trustees of Boston University (Boston, Massachusetts)
ASSIGNEE(S) Trustees of Boston University (Boston, Massachusetts)
INVENTOR(S) Siddharth Ramachandran (Boston, Massachusetts);  Zelin Ma (Boston, Massachusetts)
ABSTRACT An optical fiber system exploits a principle of topological confinement for guided higher-order modes, in contrast to more conventional total-internal-reflection (TIR) confinement. The optical fiber has a geometry and index profile defining a cutoff wavelength for a predetermined L-mode of optical signal propagation in the optical fiber, where L is azimuthal mode index. An optical source subsystem is coupled to the optical fiber to establish an optical signal propagating in the optical fiber, wherein the optical signal has the predetermined L-mode and a wavelength being either (1) at least 15% above the cutoff wavelength such that the optical beam propagates as a topologically confined mode, or (2) sufficiently above the cutoff wavelength that, based on the L-mode of the optical beam, the optical beam propagates as a topologically confined mode having propagation loss less than 3 dB/meter.
FILED Sunday, May 09, 2021
APPL NO 17/315314
ART UNIT 2883 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/14 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11508462 Therien et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) DUKE UNIVERSITY (Durham, North Carolina)
ASSIGNEE(S) DUKE UNIVERSITY (Durham, North Carolina)
INVENTOR(S) Michael Therien (Durham, North Carolina);  Yusong Bai (Durham, North Carolina);  Jean-Hubert Olivier (Durham, North Carolina);  George Bullard (Durham, North Carolina)
ABSTRACT An optoelectronic system can include a single walled carbon nanotube (SWNT) device. The SWNT can include a carrier-doping density with optical conditions that control trion formation that respond via optical, electrical, or magnetic stimuli. The carrier-doping density can include a hole-polaron or electron-polaron concentration.
FILED Monday, December 17, 2018
APPL NO 16/222704
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 10/00 (20130101)
B82Y 20/00 (20130101)
B82Y 30/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/17 (20170801)
C01B 32/159 (20170801)
C01B 32/174 (20170801)
C01B 2202/02 (20130101)
C01B 2202/22 (20130101)
C01B 2202/30 (20130101)

Electric Digital Data Processing
G06F 17/13 (20130101)

Computational Chemistry; Chemoinformatics; Computational Materials Science
G16C 10/00 (20190201) Original (OR) Class
G16C 20/40 (20190201)
G16C 60/00 (20190201)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 51/0049 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11508488 Ougouag et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S) Abderrafi Mohammed El-Amine Ougouag (Idaho Falls, Idaho);  Ramazan Sonat Sen (Idaho Falls, Idaho);  George W. Griffith (Idaho Falls, Idaho)
ABSTRACT A system for transferring heat from a nuclear reactor comprises a nuclear reactor comprising a nuclear fuel and a reactor vessel surrounding the nuclear reactor and a heat transfer system surrounding the nuclear reactor. The heat transfer system comprises an inner wall surrounding the nuclear reactor vessel, first fins coupled to an outer surface of inner wall, an outer wall between the inner wall and a surrounding environment, and second fins coupled to an inner surface of the outer wall and extending in a volume between the outer surface of the inner wall and the inner surface of the outer wall, the outer surface of the inner wall and the first fins configured to transfer heat from the nuclear reactor core to the second fins and the inner surface of the outer wall by thermal radiation. The heat transfer system may be directly coupled to the nuclear reactor vessel, or may be coupled to an external reflector surrounding the nuclear reactor vessel. Related heat transfer systems and systems for selectively removing heat from a nuclear reactor are disclosed.
FILED Thursday, September 10, 2020
APPL NO 17/017534
ART UNIT 2628 — Selective Visual Display Systems
CURRENT CPC
Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 7/082 (20130101)
F28D 2021/0054 (20130101)

Nuclear Reactors
G21C 1/07 (20130101)
G21C 1/326 (20130101)
G21C 9/00 (20130101)
G21C 11/06 (20130101)
G21C 15/10 (20130101)
G21C 15/12 (20130101) Original (OR) Class
G21C 15/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11508864 Stradins et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) Pauls Stradins (Golden, Colorado);  Emily Lowell Warren (Golden, Colorado);  Adele Clare Tamboli (Golden, Colorado)
ABSTRACT Presented herein are embodiments of a tandem solar panel subunit with 2-terminals, made from two 3-terminal cell tandems, whose top-cells are strongly current-mismatched to the Si 3-terminal bottom cell.
FILED Monday, August 17, 2020
APPL NO 16/995378
ART UNIT 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/0687 (20130101) Original (OR) Class
H01L 31/02021 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11508951 Ban et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  The Regents of the University of Colorado, a body corporate (Denver, Colorado)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  The Regents of the University of Colorado, a Body Corporate (Denver, Colorado)
INVENTOR(S) Chunmei Ban (Golden, Colorado);  Simon Elnicki Hafner (Palo Alto, California);  Se-Hee Lee (Superior, Colorado)
ABSTRACT An aspect of the present disclosure is a system that includes a first deposition system that includes a first cylinder having a first outer surface configured to hold a first substrate, a first spray nozzle configured to receive at least a first fluid, and a first fiber nozzle configured to receive at least a second fluid, where the first spray nozzle is configured to operate at a first voltage, the first fiber nozzle is configured to operate at a second voltage, the first cylinder is configured to be electrically connected to ground, the first spray nozzle is configured to apply onto the substrate a first plurality of at least one of particles or droplets from the first fluid, the first fiber nozzle is configured to apply onto the substrate a first fiber from the second fluid, and the first plurality of particles or droplets and the first fiber combine to form a first composite layer on the substrate.
FILED Wednesday, November 13, 2019
APPL NO 16/682064
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/043 (20130101)
H01M 4/131 (20130101)
H01M 4/0404 (20130101)
H01M 4/0407 (20130101)
H01M 4/0409 (20130101)
H01M 4/0419 (20130101) Original (OR) Class
H01M 4/1391 (20130101)
H01M 10/0525 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11508962 Belharouak et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Ilias Belharouak (Oak Ridge, Tennessee);  Nitin Muralidharan (Oak Ridge, Tennessee)
ABSTRACT A cathode active material precursor for a lithium metal oxide is provided. The cathode active material precursor comprises a metal-containing oxyhydroxide. The metal-containing oxyhydroxide comprises nickel and an additional metal. At least 50 mol. % of the nickel of the metal-containing oxyhydroxide has an oxidation state of +3. A method of forming a cathode active material precursor is also provided. The method comprises combining a nickel-containing compound, an additional metal-containing compound, an oxidizing agent, and a solvent to form a solution. The method further comprises exposing the solution to heat at a temperature of from about 30° C. to about 90° C. to form a precipitate comprising the metal-containing oxyhydroxide.
FILED Tuesday, February 04, 2020
APPL NO 16/781063
ART UNIT 1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 53/42 (20130101)
C01G 53/50 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2006/40 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/505 (20130101)
H01M 4/525 (20130101) Original (OR) Class
H01M 10/0525 (20130101)
H01M 2004/028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11509333 Ganapathy et al.
FUNDED BY
Department of Energy (DOE)
Exascale Computing Project (ECP)
PathForward Project (PATHFORWARD)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Advanced Micro Devices, Inc. (Santa Clara, California)
ASSIGNEE(S) Advanced Micro Devices, Inc. (Santa Clara, California)
INVENTOR(S) Shrikanth Ganapathy (Santa Clara, California);  John Kalamatianos (Boxborough, Massachusetts)
ABSTRACT Systems, apparatuses, and methods for implementing masked fault detection for reliable low voltage cache operation are disclosed. A processor includes a cache that can operate at a relatively low voltage level to conserve power. However, at low voltage levels, the cache is more likely to suffer from bit errors. To mitigate the bit errors occurring in cache lines at low voltage levels, the cache employs a strategy to uncover masked faults during runtime accesses to data by actual software applications. For example, on the first read of a given cache line, the data of the given cache line is inverted and written back to the same data array entry. Also, the error correction bits are regenerated for the inverted data. On a second read of the given cache line, if the fault population of the given cache line changes, then the given cache line's error protection level is updated.
FILED Thursday, December 17, 2020
APPL NO 17/125145
ART UNIT 2111 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electric Digital Data Processing
G06F 11/1064 (20130101)
G06F 12/0895 (20130101)
G06F 2212/1032 (20130101)

Coding; Decoding; Code Conversion in General
H03M 13/353 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 11504709 Peyvan
FUNDED BY
National Aeronautics and Space Administration (NASA)
Ames Research Center (ARC)
APPLICANT(S) Kianoosh Peyvan (Seattle, Washington)
ASSIGNEE(S)
INVENTOR(S) Kianoosh Peyvan (Seattle, Washington)
ABSTRACT A cell capture, disruption, and extraction method includes a introducing a plurality of abrasives in a disruption chamber, which can include diamond powder, variably and multi dimensionally disbursed therein, and a pestle positioned in the disruption chamber. The method includes agitating the abrasives by moving the disruption chamber and/or pestle, agitation of the abrasives tearing cell structure in the solution to access its contents. A binding column or size exclusion column can be positioned downstream of the disruption chamber. Cell solution can first be introduced in the disruption chamber, the abrasives capturing the cells and allowing therethrough and purging the waste content, then breaking the cell content. The lysate can then bind to an extraction matrix downstream of the disruption chamber or it can be mixed in with the abrasives.
FILED Friday, August 30, 2019
APPL NO 16/557137
ART UNIT 1799 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 15/34 (20130101)
B01D 24/007 (20130101)
B01D 24/105 (20130101)
B01D 2101/00 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502 (20130101) Original (OR) Class
B01L 2200/12 (20130101)
B01L 2300/06 (20130101)
B01L 2300/0832 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/286 (20130101)
G01N 1/4077 (20130101)
G01N 2001/2873 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11504773 Steeves et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Jet Propulsion Laboratory (JPL)
Federally Funded Research and Development Center (FFRDC)
Operated by California Institute of Technology (CALTECH) at Pasadena, CA
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) John B Steeves (Pasadena, California);  Scott N Roberts (Altadena, California);  Samuel C Bradford (Pasadena, California);  Christine A Gebara (Pasadena, California);  Christina J Naify (Pasadena, California)
ABSTRACT Systems and methods for additive manufacturing systems implementing adaptive optics in accordance with various embodiments of the invention are illustrated. One embodiment includes an additive manufacturing system including a laser source configured to form an output beam, a scanning mirror disposed in an optical path of the output beam, wherein the scanning mirror is configured to reflect and scan the output beam at a range of scan angles, a deformable mirror disposed in the optical path of the output beam, wherein the deformable mirror has a plurality of configurations for reflecting and altering a wavefront of the output beam, wherein the configuration of the deformable mirror is based on the scan angle of the scanning mirror, and a print bed configured to hold a print material, wherein the output beam is configured to fuse the print material to form a build object.
FILED Tuesday, October 08, 2019
APPL NO 16/596170
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 10/10 (20210101)
B22F 10/28 (20210101)
B22F 10/85 (20210101)
B22F 12/00 (20210101) Original (OR) Class
B22F 12/41 (20210101)
B22F 12/49 (20210101)

Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 26/073 (20130101)
B23K 26/082 (20151001)
B23K 26/0643 (20130101)
B23K 26/0648 (20130101)
B23K 26/0665 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11505485 Hicks et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Michael C. Hicks (Cleveland, Ohio);  Uday G. Hegde (Cleveland, Ohio)
ABSTRACT A supercritical water oxidation vortex reactor has a reactor shell configured to contain a pressurized and heated material including water, a burner assembly configured to create a supercritical core region in the material in the reactor shell, the supercritical core region including water above its critical point, an injector assembly configured to inject into the enclosed volume a subcritical wash stream including water below its critical point and an aspirator arranged in the enclosed volume and configured to remove a processed flow including purified water from an upper portion of the supercritical core region. The supercritical water oxidation vortex reactor is configured with an upward helical flow to transfer precipitated ionic compounds out of the supercritical core region, through a transcritical intermediate region, and into the subcritical wash stream where they re-dissolve.
FILED Wednesday, March 03, 2021
APPL NO 17/191021
ART UNIT 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 3/008 (20130101)
B01J 19/006 (20130101)
B01J 19/2415 (20130101)
B01J 19/2465 (20130101)
B01J 2219/00006 (20130101)
B01J 2219/00031 (20130101)
B01J 2219/00033 (20130101)
B01J 2219/00157 (20130101)
B01J 2219/00164 (20130101)
B01J 2219/185 (20130101)
B01J 2219/00772 (20130101)
B01J 2219/1943 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 11/086 (20130101) Original (OR) Class
C02F 2101/30 (20130101)
C02F 2201/002 (20130101)
C02F 2301/026 (20130101)
C02F 2301/066 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11506592 Javanmard et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
National Science Foundation (NSF)
APPLICANT(S) Rutgers, the State University of New Jersey (New Brunswick, New Jersey)
ASSIGNEE(S) Rutgers, the State University of New Jersey (New Brunswick, New Jersey)
INVENTOR(S) Mehdi Javanmard (West Windsor, New Jersey);  Abbas Furniturewalla (Collegeville, Florida)
ABSTRACT This disclosure provides an impedance cytometer which includes a carrier that can be attached to a living being, with a biosensor mounted thereto. The bio sensor includes a microfluidic flow channel, formed in the carrier, and an impedance circuit. The microfluidic flow channel accommodates passage of a particle therethrough. The impedance circuit, connected to the microfluidic flow channel, includes a signal generator that produces a high-frequency drive signal applied to the flow channel to produce a biosensor output signal having high-frequency variation resulting from the drive signal and low-frequency variation resulting from impedance variation within the flow channel during the particle's passage. A lock-in amplifier is disposed to (i) amplify the bio sensor output signal, (ii) mix the amplified signal with the drive signal, and (iii) frequency-filter the mixed, amplified signal to output an impedance signal representing the low-frequency impedance variation resulting from the passage of the particle. Embodiments enable wearable, personalized cytometry.
FILED Thursday, October 17, 2019
APPL NO 16/656148
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/02 (20130101)
G01N 15/1209 (20130101)
G01N 15/1404 (20130101) Original (OR) Class
G01N 33/4836 (20130101)
G01N 2015/008 (20130101)
G01N 2015/0073 (20130101)
G01N 2015/1006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11506620 Righter
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Kevin Righter (Houston, Texas)
ABSTRACT A double capsule assembly includes an outer capsule and an inner capsule configured to be positioned within the outer capsule. The inner capsule is configured to have a sample positioned therein. The double capsule assembly is configured to be placed in a solid media assembly to analyze or synthesize the sample.
FILED Tuesday, July 16, 2019
APPL NO 16/513087
ART UNIT 2853 — Printing/Measuring and Testing
CURRENT CPC
Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals
C01F 7/162 (20130101)

Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 37/14 (20130101)
C01G 41/006 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/32 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/203 (20130101)
G01N 25/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11506951 Ram et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Aeronautics and Space Administration (NASA)
Jet Propulsion Laboratory (JPL)
Federally Funded Research and Development Center (FFRDC)
Operated by California Institute of Technology (CALTECH) at Pasadena, CA
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Rajeev J. Ram (Arlington, Massachusetts);  Dodd Joseph Gray (San Francisco, California);  Amir H. Atabaki (San Francisco, California);  Marc De Cea Falco (Cambridge, Massachusetts)
ABSTRACT Optical read-out of a cryogenic device (such as a superconducting logic or detector element) can be performed with a forward-biased optical modulator that is directly coupled to the cryogenic device without any intervening electrical amplifier. Forward-biasing at cryogenic temperatures enables very high modulation efficiency (1,000-10,000 pm/V) of the optical modulator, and allows for optical modulation with millivolt driving signals and microwatt power dissipation in the cryogenic environment. Modulated optical signals can be coupled out of the cryostat via an optical fiber, reducing the thermal load on the cryostat. Using optical fiber instead of electrical wires can increase the communication bandwidth between the cryogenic environment and room-temperature environment to bandwidth densities as high as Tbps/mm2 using wavelength division multiplexing. Sensitive optical signals having higher robustness to noise and crosstalk, because of their immunity to electromagnetic interference, can be carried by the optical fiber.
FILED Friday, November 06, 2020
APPL NO 17/091905
ART UNIT 2883 — Optics
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/0102 (20130101)
G02F 1/0123 (20130101)
G02F 1/212 (20210101)
G02F 1/2257 (20130101) Original (OR) Class
G02F 2202/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11509108 Delavaux et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Cybel, LLC. (Bethlehem, Pennsylvania)
ASSIGNEE(S) Cybel, LLC. (Bethlehem, Pennsylvania)
INVENTOR(S) Jean-Marc Delavaux (Pittstown, New Jersey);  Robert E. Tench (Allentown, Pennsylvania);  Alexandre Amavigan (Whitehall, Pennsylvania)
ABSTRACT A multi-stage thulium-doped (Tm-doped) fiber amplifiers (TDFA) is based on the use of single-clad Tm-doped optical fiber and includes a wavelength conditioning element to compensate for the nonuniform spectral response of the initial stage(s) prior to providing power boosting in the output stage. The wavelength conditioning element, which may comprise a gain shaping filter, exhibits a wavelength-dependent response that flattens the gain profile and output power distribution of the amplified signal prior to reaching the output stage of the multi-stage TDFA. The inclusion of the wavelength conditioning element allows the operating bandwidth of the amplifier to be extended so as to encompass a large portion of the eye-safe 2 μm wavelength region.
FILED Friday, May 01, 2020
APPL NO 16/864528
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/0941 (20130101)
H01S 3/1003 (20130101)
H01S 3/1616 (20130101)
H01S 3/06708 (20130101)
H01S 3/06758 (20130101) Original (OR) Class
H01S 3/094003 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11509145 Rentel
FUNDED BY
National Aeronautics and Space Administration (NASA)
Glenn Research Center (GLENN)
APPLICANT(S) X-wave Innovations, Inc. (Gaithersburg, Maryland)
ASSIGNEE(S) X-Wave Innovations, Inc. (Gaithersburg, Maryland)
INVENTOR(S) Carlos Rentel (Poolesville, Maryland)
ABSTRACT The present disclosure relates to methods and systems for management and control of interconnected energy storage modules, such as battery packs, that can form a larger energy storage system. The disclosure also relates to methods and system for the measurement of cell impedances in a battery pack in-situ and on-line and using active balancing circuits that may already be present in the battery pack. The methods and systems can inject disturbances of different frequencies and measure impedance by using the active balancing circuits present in the battery pack, which can transform an active balancer into a dual active balancer and impedance measurement system. The speed up of impedance measurement energy storage modules can be accomplished by using multi-tone, orthogonal or spread spectrum waveforms applied simultaneously on all or a sub-set of the active balancer circuits in an active balancer.
FILED Saturday, June 13, 2020
APPL NO 16/900906
ART UNIT 2851 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/389 (20190101)
G01R 31/396 (20190101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 7/0014 (20130101) Original (OR) Class
H02J 7/0047 (20130101)
H02J 7/00712 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 11504746 Nagy et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) UNITED STATES POSTAL SERVICE (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES POSTAL SERVICE (Washington, District of Columbia)
INVENTOR(S) Michael A. Nagy (Warrenton, Virginia);  Dirk H. Sattler (Gainesville, Virginia)
ABSTRACT Systems, methods, and devices for designating a location for a delivery item that is being sorted by an operator. The operator scans the delivery address of the item using a scanner having a particular attribute, such as being painted red. Using delivery address along with an identifier for the scanner that was used, the system determines a sort output location for the item, identifies a designator (e.g. a specific color, such as red) that corresponds to the scanner, and identifies an indicator device (e.g., a multicolor LED device) that corresponds to the sort output location. The system then commands the indicator device to present or display the designator. For example, the indicator device may be commanded to illuminate a LED to give off red light. The operator of the red scanner then places the item at the location corresponding to the red light designator.
FILED Thursday, April 02, 2020
APPL NO 16/838214
ART UNIT 3653 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking
B07C 3/008 (20130101)
B07C 3/14 (20130101) Original (OR) Class
B07C 3/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11507764 Stephen et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Victoria K. Stephen (Burke, Virginia);  Elke Reuning-Elliott (Rosslyn, Virginia)
ABSTRACT A distribution item includes a first item comprising a container having an outer surface defining an enclosed space. A computer-readable code is disposed on the outer surface. The computer-readable code is associated with a first level entity. The first item also includes destination information associated with a second level entity disposed on the outer surface. The distribution item also includes one or more second items removably positioned within the enclosed space of the first item. Each of the one or more second items includes the computer-readable code associated with the first level entity.
FILED Friday, September 18, 2020
APPL NO 17/025533
ART UNIT 2876 — Optics
CURRENT CPC
Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking
B07C 3/10 (20130101)
B07C 3/14 (20130101)

Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus
B42D 5/025 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 7/1413 (20130101)
G06K 7/1417 (20130101)
G06K 7/10861 (20130101) Original (OR) Class

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/0833 (20130101)

Ticket-issuing Apparatus; Fare-registering Apparatus; Franking Apparatus
G07B 2017/00475 (20130101)
G07B 2017/00588 (20130101)
G07B 2017/00596 (20130101)
G07B 2017/00709 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11508024 Irwin et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Donald E. Irwin (Fredericksburg, Virginia);  Nan K. McKenzie (Garrett Park, Maryland);  William A. Tartal (Baltimore, Maryland);  Victoria K. Stephen (Burke, Virginia);  Michael J. Amato (Reston, Virginia);  William G. Ackerman (Washington, District of Columbia);  Robert E. Dixon (Washington, District of Columbia);  Daniel W. Smith (Washington, District of Columbia);  Gregory Crabb (Broadlands, Virginia);  Paul Anthony Bernicchi (Land O Lakes, Florida)
ABSTRACT A system and method of verifying the identity of a user or registrant. The user or registrant provides identification information and registration information. The identification information may be a visual representation of an identifying item associated with location information. In some embodiments, the identification information may be a visual representation of a government issued identity. An identification module verifies the identification information and compares the verified identification information to the registration information.
FILED Friday, April 23, 2021
APPL NO 17/239386
ART UNIT 3692 — Business Methods - Finance/Banking/ Insurance
CURRENT CPC
Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 20/405 (20130101)
G06Q 20/4014 (20130101)
G06Q 30/0185 (20130101)
G06Q 50/265 (20130101) Original (OR) Class

Image or Video Recognition or Understanding
G06V 30/418 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 11507135 Cheung et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland)
ASSIGNEE(S) GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland)
INVENTOR(S) Kin P Cheung (Rockville, Maryland);  Joseph W Robertson (Washington, District of Columbia);  John J Kasianowicz (Darnestown, Maryland)
ABSTRACT A molecular scrivener reads data from or writes data to a macromolecule and includes: a pair of shielding electrodes; a scrivener electrode between the first and second shielding electrodes and that electrically floats at a third potential that, in an absence of a charged or dipolar moiety of the macromolecule, is intermediate between the first and second potentials and changes in a presence of the charged or dipolar moiety; a dielectric layer interposed between shielding electrodes and the scrivener electrode; and a nanopore that communicates the macromolecule through the electrodes and dielectric layers. Reading data from or writing data to a macromolecule includes: sequentially receiving, at the scrivener electrode, individual moieties of the macromolecule so that the third potential responds to individual moieties; communicating the macromolecule from the scrivener electrode to the second shielding electrode and from second shielding electrode to expel the macromolecule from the nanopore.
FILED Monday, April 15, 2019
APPL NO 16/383707
ART UNIT 2824 — Semiconductors/Memory
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 35/00 (20130101)

Electric Digital Data Processing
G06F 1/1613 (20130101) Original (OR) Class

Static Stores
G11C 13/0016 (20130101)
G11C 13/0019 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 11508865 Kanatzidis et al.
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Mercouri G. Kanatzidis (Wilmette, Illinois);  Wenwen Lin (Evanston, Illinois)
ABSTRACT A semiconductor material having the molecular formula Cu2l2Se6 is provided. Also provided are solid solutions of semiconductor materials having the formulas Cu2lxBr2-xSeyTe6-y and Cu2lxBr2-xSeyS6-y, where 0≤x≤1 and 0≤y≤3. Methods and devices that use the semiconductor materials to convert incident radiation into an electric signal are also provided. The devices include optoelectronic and photonic devices, such as photodetectors, photodiodes, and photovoltaic cells.
FILED Monday, July 16, 2018
APPL NO 16/627894
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Measurement of Nuclear or X-radiation
G01T 1/241 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/032 (20130101)
H01L 31/072 (20130101)
H01L 31/085 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 11504286 Cooper et al.
FUNDED BY
Department of Veterans Affairs (DVA)
National Science Foundation (NSF)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia);  FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (Munich, Germany)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia);  FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (Munich, Germany)
INVENTOR(S) Rory Alan Cooper (Gibsonia, Pennsylvania);  Hongwu Wang (Edmond, Oklahoma);  Brandon Joseph Daveler (Pittsburgh, Pennsylvania);  Benjamin Todd Gebrosky (Gibsonia, Pennsylvania);  Garrett G. Grindle (Pittsburgh, Pennsylvania);  Jonathan L. Pearlman (Pittsburgh, Pennsylvania);  Urs Schneider (Stuttgart, Germany);  David Minzenmay (Stuttgart, Germany)
ABSTRACT A personal mobility device includes a frame, a plurality of wheels attached to the frame and one or more pneumatic motors. Each of the one or more pneumatic motors has a drive shaft in operative connection with at least one of the plurality of wheels. The personal mobility device further includes at least one tank (that is, a storage container) for storage of a pressurized gas in operative connection with the one or more pneumatic motors to supply pressurized gas to the one or more pneumatic motors and a control system in operative connection with the at least one tank and with the one or more pneumatic motors.
FILED Wednesday, January 04, 2017
APPL NO 16/067992
ART UNIT 3611 — Material and Article Handling
CURRENT CPC
Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices
A61G 5/04 (20130101) Original (OR) Class
A61G 5/10 (20130101)
A61G 5/045 (20130101)
A61G 5/048 (20161101)
A61G 5/1051 (20161101)

Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles
B60K 7/0023 (20130101)
B60K 2007/0038 (20130101)
B60K 2007/0092 (20130101)

Indexing Scheme Relating to Aspects Cross-cutting Vehicle Technology
B60Y 2200/13 (20130101)
B60Y 2200/84 (20130101)
B60Y 2200/126 (20130101)

Positive-displacement Engines Driven by Liquids
F03C 2/00 (20130101)

Gearing
F16H 7/06 (20130101)
F16H 48/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 11509108 Delavaux et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Cybel, LLC. (Bethlehem, Pennsylvania)
ASSIGNEE(S) Cybel, LLC. (Bethlehem, Pennsylvania)
INVENTOR(S) Jean-Marc Delavaux (Pittstown, New Jersey);  Robert E. Tench (Allentown, Pennsylvania);  Alexandre Amavigan (Whitehall, Pennsylvania)
ABSTRACT A multi-stage thulium-doped (Tm-doped) fiber amplifiers (TDFA) is based on the use of single-clad Tm-doped optical fiber and includes a wavelength conditioning element to compensate for the nonuniform spectral response of the initial stage(s) prior to providing power boosting in the output stage. The wavelength conditioning element, which may comprise a gain shaping filter, exhibits a wavelength-dependent response that flattens the gain profile and output power distribution of the amplified signal prior to reaching the output stage of the multi-stage TDFA. The inclusion of the wavelength conditioning element allows the operating bandwidth of the amplifier to be extended so as to encompass a large portion of the eye-safe 2 μm wavelength region.
FILED Friday, May 01, 2020
APPL NO 16/864528
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/0941 (20130101)
H01S 3/1003 (20130101)
H01S 3/1616 (20130101)
H01S 3/06708 (20130101)
H01S 3/06758 (20130101) Original (OR) Class
H01S 3/094003 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. Agency for International Development (USAID) 

US 11505804 Mengiste et al.
FUNDED BY
U.S. Agency for International Development (USAID)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Tesfaye D Mengiste (West Lafayette, Indiana);  Fuyou Fu (Saskatoon, Canada);  Sanghun Lee (West Lafayette, Indiana);  Gebisa Ejeta (West Lafayette, Indiana)
ABSTRACT Disclosed herein is a unique molecular marker in sorghum genome for conferring broad range fungal resistance trait, and the use of the molecular marker to manipulate resistance in sorghum. A disease resistance gene called ANTHRACNOSE RESISTANCE GENE 1 (ARG1) and a negative regulator, i.e. antisense transcripts of ARG1, called CARRIER OF ARG (CARG) for the fungi resistance gene are knocked out within a quantitative trait locus (QTL).
FILED Wednesday, November 21, 2018
APPL NO 16/766218
ART UNIT 1662 — Plants
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/8282 (20130101) Original (OR) Class

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6895 (20130101)
C12Q 2600/13 (20130101)
C12Q 2600/156 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 11507859 Stromer-Galley et al.
FUNDED BY
APPLICANT(S) COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colorado);  Syracuse University (Syracuse, New York);  The Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
ASSIGNEE(S) COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colorado);  Syracuse University (Syracuse, New York);  The Arizona Board of Regent on Behalf of the University of Arizona (Tucson, Arizona)
INVENTOR(S) Jennifer Stromer-Galley (Cazenovia, New York);  Brian McKernan (East Meadow, New York);  Patricia Rossini (Liverpool, United Kingdom);  Carsten Oesterlund (Syracuse, New York);  Lael Jeremy Schooler (Fayetteville, New York);  James Eric Folkestad (Fort Collins, Colorado);  Benjamin Clegg (Timnath, Colorado);  Rosa Mikeal Martey (Fort Collins, Colorado);  Kate Marian Kenski (Tucson, Arizona);  Roc Aron Myers (Ashburn, Virginia);  Sarah M. Taylor (Sedgwick, Maine)
ABSTRACT In an example, a computer-implemented method to structure an analytical workflow that improves reasoning based on a problem context and demonstrated abilities of each individual user may include displaying a reasoning problem to an analyst. The method may include receiving input from the analyst to identify a reasoning problem type of the reasoning problem. providing a recommended analytic approach for the reasoning problem type to the analyst. The method may include assisting the analyst in analyzing and evaluating one or more information sources relevant to the reasoning problem. The method may include guiding the analyst through a structured technique (ST) to support reasoning of the analyst in formulation of a solution to the reasoning problem. The method may include generating a report that includes the analyst's solution to the reasoning problem based on input from the analyst.
FILED Wednesday, January 08, 2020
APPL NO 16/737799
ART UNIT 2628 — Selective Visual Display Systems
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 5/003 (20130101)
G06N 5/04 (20130101) Original (OR) Class
G06N 7/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, November 22, 2022.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20221122.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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