FedInvent™ Patents
Patent Details for Tuesday, December 20, 2022
This page was updated on Wednesday, December 21, 2022 at 06:11 AM GMT
Department of Health and Human Services (HHS)
| US 11529108 | Tai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yuan-Chuan Tai (St. Louis, Missouri); Joseph O'Sullivan (St. Louis, Missouri); Ke Li (St. Louis, Missouri); Qiang Wang (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Yuan-Chuan Tai (St. Louis, Missouri); Joseph O'Sullivan (St. Louis, Missouri); Ke Li (St. Louis, Missouri); Qiang Wang (St. Louis, Missouri) |
| ABSTRACT | A positron emission tomography (PET) technique that can enhance the image resolution and system sensitivity of a clinical PET/CT scanner for imaging a whole body or a target region of a subject is provided. The system includes a detector array and a detector panel. The detector array includes an array of gamma ray detectors defining a field of view of a scanner and configured to detect at least one coincidence event. The detector panel includes an array of gamma ray detectors having a higher intrinsic spatial resolution than the detector array and positioned in closer proximity to a patient table than the detector array. The detector panel is positioned outside the field of view defined by the detector array during at least a portion of scanning by the PET system. The detector panel is configured to detect at least one coincidence event in cooperation with the detector array. The control unit is configured to control the detector array, the detector panel, and the patient bed to operate in cooperation with each other. |
| FILED | Wednesday, November 27, 2019 |
| APPL NO | 16/697722 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/037 (20130101) Original (OR) Class A61B 6/4233 (20130101) Measurement of Nuclear or X-radiation G01T 1/2985 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529122 | Kim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Kang Kim (Pittsburgh, Pennsylvania); Jingping Xu (Shanghai, China PRC); Jonathan M Rubin (Ann Arbor, Michigan) |
| ABSTRACT | A method of evaluating tissue stiffness of a target area includes positioning an ultrasound elasticity imaging apparatus adjacent a surface of an area of tissue where the target area is located and applying a dynamic range of force to the tissue. A plurality of ultrasound beams can be directed at the tissue and a plurality of ultrasound echoes can be acquired from the strained tissue in the target area to calculate an amount of developed strain within the target area. |
| FILED | Monday, December 23, 2019 |
| APPL NO | 16/726089 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/08 (20130101) A61B 8/085 (20130101) A61B 8/461 (20130101) A61B 8/485 (20130101) Original (OR) Class A61B 8/0858 (20130101) A61B 8/4281 (20130101) A61B 8/4483 (20130101) A61B 8/5223 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/07 (20130101) G01N 29/0654 (20130101) G01N 2291/0422 (20130101) G01N 2291/02475 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529291 | Sazonov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Alabama (Tuscaloosa, Alabama); THE UAB RESEARCH FOUNDATION (Birmingham, Alabama) |
| ASSIGNEE(S) | The Board of Trustees of the University of Alabama (Tuscaloosa, Alabama); The UAB Research Foundation (Birmingham, Alabama) |
| INVENTOR(S) | Eduard S. Sazonov (Northport, Alabama); Ariel A. Salas (Hoover, Alabama); Paula Catherine Chandler-Laney (Birmingham, Alabama) |
| ABSTRACT | A feeding bottle includes a bottle enclosure defining a hollow bottle chamber, wherein the enclosure defines a feeding outlet at a first end and an attachment structure 26 at a second end. A bottom housing defines an instrument compartment extending between a closed exterior portion of the bottom housing and a separation surface within the bottom housing, wherein the bottom housing is configured for detachable connection to the attachment structure 26 of the bottle enclosure. A relief valve is positioned within the separation surface of the bottom housing. A pressure sensor is positioned adjacent the separation surface of the bottom housing and connected by a passageway to the instrument compartment in the bottom housing, wherein the pressure sensor is configured to detect changes of pressure in the bottle enclosure. |
| FILED | Friday, October 25, 2019 |
| APPL NO | 16/664437 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 9/001 (20130101) A61J 9/008 (20130101) Original (OR) Class A61J 11/008 (20130101) A61J 2200/70 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 27/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529312 | Bosio et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Catharine Mans Bosio (Hamilton, Montana); Robin M. Ireland (Hamilton, Montana); Glenn A. Nardone (Rockville, Maryland) |
| ABSTRACT | Embodiments of the present disclosure include anti-inflammatory compositions and methods of use thereof. The compositions include purified lipids from Francisella, for example, virulent strains of Francisella. Other features and advantages of the invention will be apparent from the detailed description, and from the claims. |
| FILED | Thursday, April 06, 2017 |
| APPL NO | 16/091768 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1271 (20130101) Original (OR) Class A61K 31/685 (20130101) A61K 31/685 (20130101) A61K 31/6615 (20130101) A61K 31/6615 (20130101) A61K 39/0208 (20130101) A61K 2039/58 (20130101) A61K 2039/55555 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) A61P 29/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529314 | Cui et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Zhengrong Cui (Austin, Texas); Abdulaziz Aldayel (Austin, Texas); Hannah O'Mary (Austin, Texas) |
| ABSTRACT | Disclosed herein are nanoparticles comprising a lipid core comprising a sterol; and a complex comprising a cationic agent and a therapeutic agent, wherein the complex is encapsulated within the lipid core. Methods to produce the nanoparticle comprise: combining a cationic agent, a therapeutic agent, and a first water-immiscible solvent with a first aqueous solution, thereby forming a mixture comprising a complex comprising the cationic agent and the therapeutic agent; combining the mixture with a second waterim-miscible solvent, thereby forming an aqueous phase and an organic phase, and separating the organic phase comprising the complex; combining the organic phase comprising the complex with a sterol and a first water-miscible organic solvent; and dispersing the complex in a second aqueous solution to form a herein disclosed nanoparticle. Methods for treating a disease and for reducing nanoparticle burst rate are also disclosed. |
| FILED | Wednesday, November 07, 2018 |
| APPL NO | 16/762654 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1272 (20130101) A61K 9/5123 (20130101) Original (OR) Class A61K 9/5192 (20130101) A61K 31/395 (20130101) A61K 31/573 (20130101) A61K 31/713 (20130101) A61K 47/28 (20130101) A61K 47/60 (20170801) A61K 47/543 (20170801) A61K 47/6929 (20170801) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529323 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| INVENTOR(S) | Ching-Shih Chen (Columbus, Ohio); Christopher C. Coss (Columbus, Ohio); Samuel Kulp (Columbus, Ohio); Yu-Chou Tseng (Columbus, Ohio); Tanios Bekaii-Saab (Columbus, Ohio) |
| ABSTRACT | In one aspect, the disclosure relates to methods and compositions for treatment of cancer cachexia. In a further aspect, the composition is a pharmaceutical composition comprising a class I/IIB HDAC inhibitor and an androgen. In a still further aspect, the method of treatment comprises administering a class I/IIB HDAC inhibitor and an androgen to a subject or patient who has been diagnosed as having cancer cachexia. In some aspects, the class I/IIB HDAC inhibitor is a compound known as AR-42. |
| FILED | Thursday, September 13, 2018 |
| APPL NO | 16/646424 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/167 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529324 | Brelidze et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgetown University (Washington, District of Columbia) |
| ASSIGNEE(S) | GEORGETOWN UNIVERSITY (Washington, District of Columbia) |
| INVENTOR(S) | Tinatin I. Brelidze (Washington, District of Columbia); Yuichiro J. Suzuki (Bethesda, Maryland); Nataliia Shults (Ashburn, Virginia); Vladyslava Rybka (Ashburn, Virginia) |
| ABSTRACT | Provided are methods of treating pulmonary artery hypertension with a Kv11.1 (ERG or hERG1) channel inhibitor. In certain embodiments, the Kv11.1 channel inhibitor is dofetilide. In certain embodiments, a subject to be treated using a method of the disclosure is not in need of treatment for an irregular heart rhythm, e.g., atrial fibrillation. |
| FILED | Thursday, May 21, 2020 |
| APPL NO | 16/880376 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 9/0073 (20130101) A61K 31/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529335 | Schultz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| ASSIGNEE(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| INVENTOR(S) | Michael K. Schultz (Iowa City, Iowa); Somya Kapoor (Iowa City, Iowa); Douglas R. Spitz (Iowa City, Iowa) |
| ABSTRACT | The invention provides compositions and methods to treat a hyperproliferative disorder with a GSH synthesis inhibitor and an anti-cancer composition. |
| FILED | Friday, July 31, 2020 |
| APPL NO | 16/945323 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/66 (20130101) A61K 31/198 (20130101) A61K 31/437 (20130101) Original (OR) Class A61K 31/4706 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) Peptides C07K 16/2818 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529338 | Freeman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| ASSIGNEE(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| INVENTOR(S) | Michael Freeman (West Hollywood, California); Mirja Rotinen (Beverly Hills, California); Ramachandran Murali (Beverly Hills, California); Sungyong You (Los Angeles, California) |
| ABSTRACT | Provided herein are compositions and methods for treating, inhibiting and/or reducing the severity of neuroblastoma, small cell lung cancer (SCLC), large cell neuroendocrine cancer (LCNEC), large-cell carcinoma (LCC), squamous cell carcinoma (SqCC), and/or adenocarcinoma (AC) in subjects in need thereof. The methods include providing an agent that inhibits expression or activity of ONECUT2 and administering a therapeutically effective amount of the agent so as to treat, inhibit and/or reduce the severity of neuroblastoma, small cell lung cancer (SCLC), large cell neuroendocrine cancer (LCNEC), large-cell carcinoma (LCC), squamous cell carcinoma (SqCC), and/or adenocarcinoma (AC) in the subject. |
| FILED | Wednesday, August 22, 2018 |
| APPL NO | 16/640902 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/165 (20130101) A61K 31/343 (20130101) A61K 31/381 (20130101) A61K 31/397 (20130101) A61K 31/416 (20130101) A61K 31/445 (20130101) Original (OR) Class A61K 31/4164 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529340 | Wilcox et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota); George Latimer Wilcox (Minneapolis, Minnesota); Daniel John Bruce (Minneapolis, Minnesota); Carolyn Ann Fairbanks (Minneapolis, Minnesota); Philip S. Portoghese (Minneapolis, Minnesota); Eyup Akgun (Minneapolis, Minnesota) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | George Latimer Wilcox (Minneapolis, Minnesota); Daniel John Bruce (Minneapolis, Minnesota); Carolyn Ann Fairbanks (Minneapolis, Minnesota); Philip S. Portoghese (Minneapolis, Minnesota); Eyup Akgun (Minneapolis, Minnesota) |
| ABSTRACT | The invention provides compounds, compositions, and methods for treating pain. |
| FILED | Wednesday, March 22, 2017 |
| APPL NO | 16/088000 |
| ART UNIT | 1699 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/451 (20130101) Original (OR) Class A61K 31/485 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529349 | Wasmuth et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Andrew Wasmuth (Brooklyn, New York); Donald W. Landry (New York, New York); Shixian Deng (White Plains, New York); Banavara L. Mylari (East Lyme, Connecticut); Ravichandran Ramasamy (Ardsley, New York); Ann Marie Schmidt (Franklin Lakes, New Jersey) |
| ABSTRACT | The present invention relates to novel compounds and pharmaceutical compositions thereof, and methods for promoting healthy aging of skin, the treatment of skin disorders, the treatment of cardiovascular disorders, the treatment of renal disorders, the treatment of angiogenesis disorders, such as cancer, treatment of tissue damage, such as non-cardiac tissue damage, the treatment of evolving myocardial infarction, and the treatment of various other disorders, such as complications arising from diabetes with the compounds and compositions of the invention. Other disorders can include, but are not limited to, atherosclerosis, coronary artery disease, diabetic nephropathy, diabetic neuropathy, diabetic retinopathy, infections of the skin, peripheral vascular disease, stroke, and the like. |
| FILED | Thursday, October 10, 2019 |
| APPL NO | 16/598119 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/5025 (20130101) Original (OR) Class Heterocyclic Compounds C07D 487/04 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 999/99 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529358 | Bassell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | EMORY UNIVERSITY (Atlanta, Georgia); UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia); University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Gary Bassell (Atlanta, Georgia); Andrew Jenkins (Decatur, Georgia); David B. Rye (Dunwoody, Georgia); Maurice Scott Swanson (Gainesville, Florida); Eric Tzy-Shi Wang (Gainesville, Florida); Lyndon Lien (Hillsborough, California) |
| ABSTRACT | Disclosed are methods of treating a disorder or disease associated with myotonic dystrophy. Methods of treating a CNS dysfunction and/or cognitive impairment associated with myotonic dystrophy in a subject comprising administering a therapeutically effective amount of a GABAA receptor antagonist or inverse agonist to the subject are disclosed. Methods of treating a myotonic dystrophy associated disease or disorder caused by mis-splicing of GABRG2 in a subject comprising administering a therapeutically effective amount of a GABAA receptor antagonist or inverse agonist to the subject are disclosed. Methods of improving cognitive function or alertness in a subject having myotonic dystrophy comprising administering a therapeutically effective amount of a GABAA receptor antagonist or inverse agonist to the subject are disclosed. Examples of the GABAA receptor antagonist or inverse agonist include flumazenil, clarithromycin, a fluoroquinolone, picrotoxin, bicuculline, gabazine, cicutoxin, oenan-thotoxin, pentylenetetrazol, Ro15-4513, sarmazenil, amentoflavone, zinc, and any combination thereof. |
| FILED | Thursday, May 10, 2018 |
| APPL NO | 16/612192 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/5517 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529366 | Machielse et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mandos LLC (West Hollywood, California) |
| ASSIGNEE(S) | Mandos LLC (West Hollywood, California) |
| INVENTOR(S) | Bernardus Nicolaas Machielse (North Potomac, Maryland); Allan Darling (North Potomac, Maryland) |
| ABSTRACT | This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C. |
| FILED | Monday, May 16, 2022 |
| APPL NO | 17/745505 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/0019 (20130101) A61K 9/0085 (20130101) A61K 31/724 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529388 | Wickline et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of South Florida (Tampa, Florida); Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | University of South Florida (, None); Washington University (, None) |
| INVENTOR(S) | Samuel A. Wickline (Temple Terrace, Florida); Hua Pan (Tampa, Florida); Christine Thien-Nga Pham (St. Louis, Missouri); Huimin Yan (St. Louis, Missouri) |
| ABSTRACT | The present disclosure relates to nanoparticles and methods for polynucleotide transfection. |
| FILED | Friday, May 08, 2020 |
| APPL NO | 16/870035 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/51 (20130101) A61K 31/7105 (20130101) A61K 38/16 (20130101) Original (OR) Class A61K 47/64 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) A61P 19/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529391 | Longaker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Michael T. Longaker (Atherton, California); Irving L. Weissman (Stanford, California); Ruth Tevlin (Stanford, California); Charles K. F. Chan (Redwood City, California) |
| ABSTRACT | Methods and compositions are provided for the therapeutic use of hedgehog agents, for enhancing bone growth and regeneration in diabetic or pre-diabetic patients, including repair following injury, osseointegration of implants, and the like. In some embodiments of the invention, the compositions are administered locally, e.g. by injection or implantation at the site of an injury. |
| FILED | Monday, January 08, 2018 |
| APPL NO | 16/475353 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) A61P 19/00 (20180101) Peptides C07K 14/435 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529397 | Montaño-Suarez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Adriana M. Montaño-Suarez (St. Louis, Missouri); Angela Catalina Sosa-Molano (Bogotá, Colombia); Alan Knutsen (Webster Groves, Missouri); Clifford Bellone (St. Louis, Missouri); Shunji Tomatsu (Wilmington, Delaware); Luis Barrera (Bogotá, Colombia) |
| ASSIGNEE(S) | Saint Louis University (St. Louis, Missouri) |
| INVENTOR(S) | Adriana M. Montaño-Suarez (St. Louis, Missouri); Angela Catalina Sosa-Molano (Bogotá, Colombia); Alan Knutsen (Webster Groves, Missouri); Clifford Bellone (St. Louis, Missouri); Shunji Tomatsu (Wilmington, Delaware); Luis Barrera (Bogotá, Colombia) |
| ABSTRACT | Disclosed are methods and compositions for determining immunodominant peptides of target enzymes used in enzyme replacement therapy for lysosomal storage disorders. More specifically disclosed are immunodominant peptides for N-acetylgalactosamine-6-sulfatase (GALNS). Also disclosed are methods of inducing oral tolerance towards a target enzyme through oral administration of immunodominant peptides prior to commencing enzyme replacement therapy. More specifically disclosed is a method of inducing oral tolerance for GALNS, by orally administering specific immunodominant peptides for GALNS; in subjects suffering from mucopolysaccharidosis type IVA prior to commencing enzyme replacement therapy using GALNS. |
| FILED | Monday, January 22, 2018 |
| APPL NO | 15/876892 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 38/465 (20130101) Original (OR) Class Enzymes C12Y 301/06004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
11529404 — Doubly attenuated late liver stage malaria parasites and related compositions and methods
| US 11529404 | Vaughan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SEATTLE CHILDREN'S HOSPITAL (Seattle, Washington) |
| ASSIGNEE(S) | SEATTLE CHILDREN'S HOSPITAL (Seattle, Washington) |
| INVENTOR(S) | Ashley M. Vaughan (Seattle, Washington); Stefan H. I. Kappe (Seattle, Washington); Dorender A. Dankwa (Seattle, Washington) |
| ABSTRACT | The disclosure relates to doubly attenuated malaria parasites that have had the functionality of LISP2 and PlasMei2 genes interrupted through genetic manipulation. The double attenuated malaria parasites disclosed herein are useful for methods and compositions for stimulating of vertebrate host immune systems because of the complete cessation of lifecycle progression in the late liver stage, while providing a comprehensive antigenic presentation representing wildtype liver stage parasites. The disclosure also relates to the additional blood stage and gametocyte antigens to compositions of genetically attenuated malaria parasites (GAPs) to enhance efficient immune stimulation and prevention of disease and transmission related to the presence of blood stage parasites. |
| FILED | Monday, February 01, 2021 |
| APPL NO | 17/163932 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/015 (20130101) Original (OR) Class A61K 2039/522 (20130101) Peptides C07K 14/445 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/36 (20130101) C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529408 | Balint et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Etubics Corporation (Seattle, Washington) |
| ASSIGNEE(S) | Etubics Corporation (Seattle, Washington) |
| INVENTOR(S) | Joseph P. Balint (Seattle, Washington); Frank R. Jones (Seattle, Washington); Richard B. Gayle, III (Seattle, Washington) |
| ABSTRACT | Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided. |
| FILED | Thursday, August 04, 2022 |
| APPL NO | 17/881131 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/191 (20130101) A61K 38/193 (20130101) A61K 38/204 (20130101) A61K 38/208 (20130101) A61K 38/217 (20130101) A61K 38/2013 (20130101) A61K 38/2026 (20130101) A61K 38/2033 (20130101) A61K 38/2046 (20130101) A61K 38/2066 (20130101) A61K 39/00 (20130101) A61K 39/0011 (20130101) A61K 39/12 (20130101) Original (OR) Class A61K 39/21 (20130101) A61K 39/235 (20130101) A61K 39/001106 (20180801) A61K 39/001182 (20180801) A61K 2039/54 (20130101) A61K 2039/57 (20130101) A61K 2039/545 (20130101) A61K 2039/575 (20130101) A61K 2039/5256 (20130101) A61K 2039/55555 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/005 (20130101) C07K 14/71 (20130101) C07K 14/70503 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2710/10034 (20130101) C12N 2710/10321 (20130101) C12N 2710/10334 (20130101) C12N 2710/10343 (20130101) C12N 2710/10371 (20130101) C12N 2710/20034 (20130101) C12N 2740/15034 (20130101) C12N 2740/16234 (20130101) C12N 2800/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529426 | Hasty et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Karen Hasty (Memphis, Tennessee); John Stuart (Memphis, Tennessee); Mary Christine Patterson (Cordova, Tennessee); Hongsik Cho (Germantown, Tennessee) |
| ASSIGNEE(S) | Karen Hasty (Memphis, Tennessee); John Stuart (Memphis, Tennessee); Mary Christine Patterson (Cordova, Tennessee); Hongsik Cho (Germantown, Tennessee) |
| INVENTOR(S) | Karen Adcock Hasty (Memphis, Tennessee); John Marvin Stuart (Memphis, Tennessee); Mary Christine Patterson (Cordova, Tennessee); Hongsik Cho (Germantown, Tennessee) |
| ABSTRACT | Provided are methods and compositions to target delivery of cells to a tissue lesion, thereby treating the lesion. For example, biotinylated antibodies with affinity to a lesion epitope are administered at the lesion. Reparative cells including avidin and biotin are then administered at the lesion. The reparative cells are targeted to the lesion via avidin-biotin bridges to the antibodies, with additional cells recruited to the lesion via cell-to-cell avidin-biotin bridges. In certain examples, antibody-reparative cell complexes are formed by mixing the biotinylated antibodies with the reparative cells including avidin and biotin. The complexes are then administered at the lesion. In other examples, multivalent antibodies are used to target reparative cells to the lesion, such as by binding an epitope at the lesion and an epitope present on the reparative cell. In other examples, the antibodies are chemically linked to a reparative cell or to a nanosome containing a therapeutic agent. |
| FILED | Monday, November 18, 2019 |
| APPL NO | 16/686708 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/51 (20130101) A61K 39/3955 (20130101) A61K 47/6898 (20170801) Original (OR) Class A61K 2039/505 (20130101) A61K 2039/55555 (20130101) Peptides C07K 14/78 (20130101) C07K 16/18 (20130101) C07K 16/2875 (20130101) C07K 2317/56 (20130101) C07K 2317/70 (20130101) C07K 2317/565 (20130101) C07K 2319/33 (20130101) C07K 2319/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0667 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529430 | Steinmetz |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Nicole F. Steinmetz (San Diego, California) |
| ABSTRACT | A nanoparticle for diagnostic, therapeutic, and/or theranostic applications includes a rod-shaped plant virus like particle (VLP), one or more gadolinium T1 contrast agents conjugated to an interior surface of the VLP, and a layer of polydopamine (PDA) coated over a portion of the exterior surface of the VLP. |
| FILED | Monday, December 21, 2020 |
| APPL NO | 17/129490 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 41/0052 (20130101) A61K 49/108 (20130101) A61K 49/1896 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529519 | McConnell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey) |
| ASSIGNEE(S) | The Trustees of The Stevens Institute of Technology (Hoboken, New Jersey) |
| INVENTOR(S) | George McConnell (Monroe, New York); Hanyan Li (Medford, Massachusetts) |
| ABSTRACT | A method of localizing brain regions for the purpose of guiding placement of electrodes and related implants is disclosed. The inventive method involves effecting a pulse in a patient's brain, temporally aligning readings taken from an electrode at various depths, measuring local field potentials at each depth during interstimulus intervals, performing a coherence analysis comparing the local field potential measurements of the different depths, and determining a corresponding brain region for the depths compared. |
| FILED | Friday, August 21, 2020 |
| APPL NO | 17/000198 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/377 (20210101) A61B 5/4064 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/086 (20170801) A61N 1/0534 (20130101) A61N 1/36067 (20130101) A61N 1/36096 (20130101) A61N 1/36175 (20130101) Original (OR) Class A61N 1/37241 (20130101) A61N 1/37247 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529587 | Montgomery et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cellphire, Inc. (Rockville, Maryland) |
| ASSIGNEE(S) | Cellphire, Inc. (Rockville, Maryland) |
| INVENTOR(S) | Joshua Donald Montgomery (Silver Spring, Maryland); Braden Carl Ishler (Gaithersburg, Maryland); Stephen Edward Amos (Buckeystown, Maryland); Keith Andrew Moskowitz (Westfield, Indiana); Amber Nicole Lee (Rockville, Maryland); Rafael Jorda (Bethesda, Maryland); Glen Michael Fitzpatrick (North Potomac, Maryland); Michael Alexander Mathews (Arlington, Virginia) |
| ABSTRACT | Provided herein are materials and methods for the preparation of blood products. In one aspect, provided herein is a composition including platelets or platelet derivatives and an aqueous medium, wherein the aqueous medium has a protein concentration less than 50% of the protein concentration of donor apheresis plasma. |
| FILED | Friday, May 01, 2020 |
| APPL NO | 16/865215 |
| ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 61/14 (20130101) Original (OR) Class B01D 2311/12 (20130101) B01D 2315/10 (20130101) B01D 2315/16 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0644 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530180 | Sheppard et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California); Shanghai ChemPartner Co., Ltd. (South San Francisco, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Shanghai ChemPartner Co., Ltd. (South San Francisco, California) |
| INVENTOR(S) | Dean Sheppard (Oakland, California); William F. DeGrado (San Francisco, California); Hyunil Jo (Lafayette, California); Aparna Sundaram (San Francisco, California); Richard Beresis (San Francisco, California) |
| ABSTRACT | The disclosure provides, inter alia, alpha-5 beta-1 inhibitors, pharmaceutical compositions comprising alpha-5 beta-1 inhibitors, methods for treating diseases using alpha-5 beta-1 inhibitors, and processes for making alpha-5 beta-1 inhibitors. |
| FILED | Wednesday, December 09, 2020 |
| APPL NO | 17/117004 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 279/18 (20130101) Original (OR) Class C07C 279/28 (20130101) C07C 317/14 (20130101) C07C 2601/16 (20170501) Heterocyclic Compounds C07D 213/74 (20130101) C07D 215/42 (20130101) C07D 233/88 (20130101) C07D 235/16 (20130101) C07D 239/14 (20130101) C07D 265/08 (20130101) C07D 265/36 (20130101) C07D 279/06 (20130101) C07D 295/155 (20130101) C07D 311/68 (20130101) C07D 401/12 (20130101) C07D 403/12 (20130101) C07D 413/12 (20130101) C07D 417/12 (20130101) C07D 471/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530181 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Chenglong Li (Gainesville, Florida); Liguang Mao (Gainesville, Florida) |
| ABSTRACT | The instant invention describes compounds having IL-6 modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by IL-6. |
| FILED | Friday, February 22, 2019 |
| APPL NO | 16/971528 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 207/335 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530189 | Cisar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | H. Lundbeck A/S (Valby, Denmark); THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| ASSIGNEE(S) | H. LUNDBECKA/S (Valby, Denmark); THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| INVENTOR(S) | Justin S. Cisar (San Diego, California); Cheryl A. Grice (Encinitas, California); Todd K. Jones (Solana Beach, California); Micah J. Niphakis (San Diego, California); Jae Won Chang (San Diego, California); Kenneth M. Lum (San Diego, California); Benjamin F. Cravatt (San Diego, California) |
| ABSTRACT | This disclosure provides compounds and compositions which may be modulators of MAGL and/or ABHD6 and their use as medicinal agents, processes for their preparation, and pharmaceutical compositions that include disclosed compounds as at least one active agent. The disclosure also provides for method of treating a patient in need thereof, where the patient is suffering from post-traumatic stress disorder comprising administering a disclosed compound or composition. |
| FILED | Monday, March 08, 2021 |
| APPL NO | 17/195351 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/22 (20180101) Acyclic or Carbocyclic Compounds C07C 271/10 (20130101) C07C 271/12 (20130101) Heterocyclic Compounds C07D 205/04 (20130101) C07D 207/09 (20130101) C07D 207/14 (20130101) C07D 213/38 (20130101) C07D 213/40 (20130101) C07D 213/55 (20130101) C07D 215/42 (20130101) C07D 215/46 (20130101) C07D 231/12 (20130101) C07D 231/16 (20130101) C07D 231/56 (20130101) C07D 241/04 (20130101) C07D 261/08 (20130101) C07D 263/32 (20130101) C07D 271/06 (20130101) C07D 295/26 (20130101) C07D 295/205 (20130101) Original (OR) Class C07D 307/79 (20130101) C07D 317/46 (20130101) C07D 317/58 (20130101) C07D 401/04 (20130101) C07D 401/10 (20130101) C07D 403/10 (20130101) C07D 405/14 (20130101) C07D 407/06 (20130101) C07D 413/06 (20130101) C07D 413/10 (20130101) C07D 471/04 (20130101) C07D 471/10 (20130101) C07D 487/04 (20130101) C07D 491/107 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530204 | Sherman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | David H. Sherman (Ann Arbor, Michigan); Jennifer J. Schmidt (Ann Arbor, Michigan) |
| ABSTRACT | The disclosure provides cryptophycin intermediates, cryptophycin analogs, and cryptophycin chimeric molecules useful in treating cancer, as well as methods of producing these compounds and methods of treating cancer. |
| FILED | Wednesday, September 30, 2020 |
| APPL NO | 17/039001 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 413/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530219 | Gray et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Nathanael Gray (Boston, Massachusetts); Tinghu Zhang (Brookline, Massachusetts); Eric Fischer (Chestnut Hill, Massachusetts); Zhixiang He (Brookline, Massachusetts); Guangyan Du (Jamaica Plain, Massachusetts); Katherine Donovan (Boston, Massachusetts); Radoslaw Nowak (Boston, Massachusetts); Jing Ting Christine Yuan (Brookline, Massachusetts) |
| ABSTRACT | Disclosed are compounds with immunomodulatory activity, methods of making the compounds, pharmaceutical compositions containing the compounds, and methods of using the compounds to treat diseases or disorders characterized or mediated by dysfunctional protein activity. |
| FILED | Thursday, June 27, 2019 |
| APPL NO | 17/255734 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 405/14 (20130101) C07D 473/16 (20130101) Original (OR) Class C07D 473/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530235 | Cohen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Oregon Health and Science University (Portland, Oregon) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | Michael Cohen (Portland, Oregon); Ian Carter-O'Connell (Portland, Oregon); Rory Morgan (Portland, Oregon); Haihong Jin (Portland, Oregon) |
| ABSTRACT | Mutant mono ADP-ribose-polymerases (mono-PARP) proteins and small molecule compound substrates specific for the mutant mono-PARP proteins as well as methods of using these compositions to identify protein targets of the mono-PARPs and to screen for antagonists of the mono-PARPs are described. |
| FILED | Monday, December 16, 2019 |
| APPL NO | 16/715907 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/207 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1077 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/48 (20130101) Enzymes C12Y 204/0203 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/91142 (20130101) G01N 2500/02 (20130101) G01N 2500/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530240 | Gianneschi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Nathan C. Gianneschi (Evanston, Illinois); Karen L. Christman (La Jolla, California); Andrea S. Carlini (Evanston, Illinois) |
| ABSTRACT | Cyclic peptide pro-gelator compositions, and methods of therapeutic use, which assemble into macromolecular hydrogel when administered through cleavage by endogenous enzymes upregulated at a site of tissue injury, such as a myocardial infarction. |
| FILED | Monday, June 11, 2018 |
| APPL NO | 16/620025 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0029 (20130101) A61K 38/10 (20130101) A61K 45/06 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 2300/412 (20130101) A61L 2300/414 (20130101) A61L 2400/06 (20130101) A61L 2430/20 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/00 (20130101) A61M 2210/125 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) Peptides C07K 7/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530252 | Wong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Wilson W. Wong (Brookline, Massachusetts); Jang Hwan Cho (Chestnut Hill, Massachusetts) |
| ABSTRACT | Described herein is a chimeric antigen receptor (CAR) platform with the ability to (a) serve as an ON/OFF switch (with the ability for tenability/titrability), (b) sense multiple antigens and perform logic computations, and/or (c) independently regulate multiple signaling pathways. The compositions provided herein permit the degree of control and discrimination necessary to optimize CAR T cell therapy. Also described herein are cells comprising such compositions and the use of these compositions and/or cells in the treatment of cancer. |
| FILED | Tuesday, November 22, 2016 |
| APPL NO | 15/778346 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) A61K 2039/5156 (20130101) Peptides C07K 14/315 (20130101) C07K 14/4738 (20130101) C07K 14/7051 (20130101) Original (OR) Class C07K 14/70521 (20130101) C07K 14/70578 (20130101) C07K 16/00 (20130101) C07K 16/18 (20130101) C07K 16/28 (20130101) C07K 16/30 (20130101) C07K 16/32 (20130101) C07K 2317/92 (20130101) C07K 2317/622 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) C07K 2319/70 (20130101) C07K 2319/73 (20130101) C07K 2319/80 (20130101) C07K 2319/81 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/90 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530257 | Jones et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tarran Jones (Radlett, United Kingdom); Alison Levy (Harpenden, United Kingdom); Siobhan O'Brien (Bishops Stortford, United Kingdom) |
| ABSTRACT | A chimeric mouse-human antibody for treatment of amyloid deposition diseases, pharmaceutical compositions comprising the antibody, methods and materials for producing the antibody, and methods for treating an amyloid deposition disease using the antibody and the pharmaceutical composition. |
| FILED | Thursday, June 28, 2018 |
| APPL NO | 16/626613 |
| ART UNIT | 1699 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 16/18 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/34 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530259 | Witztum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Joseph L. Witztum (San Diego, California); Sotirios Tsimikas (San Diego, California); Xuchu Que (San Diego, California) |
| ABSTRACT | The disclosure provides for methods and treatments of TLR2-mediated diseases and disorders comprising administering an antibody, antibody fragment, or polypeptide that binds to and inhibits the biological activity of oxidized phospholipids. |
| FILED | Tuesday, January 29, 2019 |
| APPL NO | 16/965271 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/60 (20130101) A61K 39/39516 (20130101) A61K 39/39533 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/06 (20180101) Peptides C07K 16/18 (20130101) Original (OR) Class C07K 2317/51 (20130101) C07K 2317/52 (20130101) C07K 2317/76 (20130101) C07K 2317/515 (20130101) C07K 2317/524 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530291 | Wilson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Thomas S. Wilson (San Leandro, California); Michael Keith Hearon (College Station, Texas); Jane P. Bearinger (Berwyn, Pennsylvania) |
| ABSTRACT | This invention relates to chemical polymer compositions, methods of synthesis, and fabrication methods for devices regarding polymers capable of displaying shape memory behavior (SMPs) and which can first be polymerized to a linear or branched polymeric structure, having thermoplastic properties, subsequently processed into a device through processes typical of polymer melts, solutions, and dispersions and then crossed linked to a shape memory thermoset polymer retaining the processed shape. |
| FILED | Monday, December 02, 2019 |
| APPL NO | 16/700116 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 45/0001 (20130101) B29C 48/00 (20190201) B29C 48/03 (20190201) B29C 51/00 (20130101) B29C 51/002 (20130101) B29C 61/06 (20130101) B29C 67/20 (20130101) B29C 71/02 (20130101) B29C 71/04 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2075/00 (20130101) B29K 2105/04 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/73 (20130101) C08G 18/83 (20130101) C08G 18/673 (20130101) C08G 18/675 (20130101) C08G 18/722 (20130101) C08G 18/758 (20130101) C08G 18/3206 (20130101) Original (OR) Class C08G 63/52 (20130101) C08G 2101/00 (20130101) C08G 2280/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530381 | Gerecht et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Sharon Gerecht (Severna Park, Maryland); Daniel Lewis (Riverside, Connecticut); Kyung Min Park (Baltimore, Maryland); T. S. Karin Eisinger (Philadelphia, Pennsylvania); M. Celeste Simon (Philadelphia, Pennsylvania) |
| ABSTRACT | The present invention describes methods for quantifying and analyzing cell migration and drug screening. Such methods include a gel (or a hydrogel) comprising a polymer, and cells that forms an oxygen gradient within the gel by controlling the balance of the diffusion of oxygen through the top of the gel and by the consumption of oxygen uptake by the cells. The migration of the cells is determined while the cells are grown in the gel of the present invention. |
| FILED | Wednesday, July 19, 2017 |
| APPL NO | 16/323882 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 41/46 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/5029 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530385 | Ince et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Tan A. Ince (Miami, Florida); Robert A. Weinberg (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides tissue culture system for primary cells (e.g. normal mammalian primary epithelial progenitors). This system includes: a) a serum-free, chemically defined cell culture media; and, b) methods for isolation and in vitro long-term propagation of primary cells (e.g. primary epithelial cells). Primary cells so isolated and cultured can be kept undifferentiated and proliferate for many weeks (>15 weeks) or population doubling (>35 PD) without senescence, or any detectable genetic alterations. Upon changing media/culture conditions, these cells can be induced to differentiate. The invention also provides methods to transform normal primary cells so cultured into “cancer stem cells.” The genetically defined cancer stem cell tumor model mimics the behavior of the disease closely, e.g., the cells are invasive, hormone responsive and metastatic when injected into mice. The tumor cells express genes that are specific to cancer stem cells identified in patient samples. |
| FILED | Tuesday, August 01, 2017 |
| APPL NO | 15/665686 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0631 (20130101) Original (OR) Class C12N 5/0693 (20130101) C12N 2500/20 (20130101) C12N 2500/22 (20130101) C12N 2500/25 (20130101) C12N 2500/32 (20130101) C12N 2500/36 (20130101) C12N 2500/38 (20130101) C12N 2500/40 (20130101) C12N 2500/50 (20130101) C12N 2501/01 (20130101) C12N 2501/11 (20130101) C12N 2501/392 (20130101) C12N 2501/395 (20130101) C12N 2503/02 (20130101) C12N 2510/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530388 | Soto-Gutierrez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Alejandro Soto-Gutierrez (Pittsburgh, Pennsylvania); Tomoji Mashimo (Osaka, Japan); Alexandra Sylvie Collin de l'Hortet (Pittsburgh, Pennsylvania); Eduardo Cervantes Alvarez (Huixquilucan, Mexico); Jorge Guzman Lepe (Pittsburgh, Pennsylvania); Kan Handa (Pittsburgh, Pennsylvania); Kazuki Takeishi (Pittsburgh, Pennsylvania); Yang Wang (Pittsburgh, Pennsylvania); Branimir Popovic (Pittsburgh, Pennsylvania) |
| ABSTRACT | Methods are disclosed herein for producing human hepatocytes from human induced pluripotent stem cells. Also provided are transgenic rats for the expansion of human hepatocytes, such as those produced using the methods disclosed herein. |
| FILED | Tuesday, February 13, 2018 |
| APPL NO | 16/485771 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0271 (20130101) A01K 2207/12 (20130101) A01K 2217/075 (20130101) A01K 2227/105 (20130101) A01K 2267/025 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/067 (20130101) Original (OR) Class C12N 5/0696 (20130101) C12N 2501/12 (20130101) C12N 2501/115 (20130101) C12N 2501/155 (20130101) C12N 2506/45 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530421 | Schaffer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | David V. Schaffer (Danville, California); Benjamin Ezra Epstein (Berkeley, California) |
| ABSTRACT | Disclosed herein is a functional nucleic acid that includes i) one or more coding nucleotide sequences encoding a genome editing endonuclease; ii) regulatory sequences operably linked to the one or more coding nucleotide sequences; and iii) one or more genome editing endonuclease-recognized sequences, wherein the functional nucleic acid is configured to express the endonuclease in a host cell and thereby provide a cellular endonuclease activity in a sequence-specific manner in the host cell, and wherein cleavage of the functional nucleic acid by the endonuclease inactivates the cellular endonuclease activity. Methods of using the present functional nucleic acid, and systems and kits that find use in performing the same are also provided. |
| FILED | Tuesday, January 31, 2017 |
| APPL NO | 16/068011 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2750/14143 (20130101) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530425 | Lu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Timothy Lu (Cambridge, Massachusetts); Shota Nakade (Somerville, Massachusetts) |
| ABSTRACT | The disclosure provides systems, methods, and compositions for a target specific nuclease and a blunting enzyme to correct frameshift mutations for genome editing and treatment of diseases. In some embodiments, the target specific nuclease and the blunting enzyme are combined with a guide RNA and/or a microhomology-mediated end joining (MMEJ) inhibitor. |
| FILED | Friday, October 09, 2020 |
| APPL NO | 17/067379 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530435 | Machyna et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Martin Machyna (New Haven, Connecticut); Matthew Simon (New Haven, Connecticut) |
| ABSTRACT | Disclosed herein are compositions and methods for detecting RNA binding sites and RNA interacting partners involving the use of a modified capture oligonucleotide having a dual toehold design. |
| FILED | Wednesday, May 15, 2019 |
| APPL NO | 16/412527 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6804 (20130101) Original (OR) Class C12Q 1/6816 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530436 | Xie et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Xiaoliang Sunney Xie (Lexington, Massachusetts); Dong Xing (Cambridge, Massachusetts); Chi-Han Chang (Cambridge, Massachusetts); Longzhi Tan (Somerville, Massachusetts) |
| ABSTRACT | The present disclosure provides a method for assembly of genomic DNA using multiplex end-tagging amplification of genomic fragments. |
| FILED | Wednesday, May 23, 2018 |
| APPL NO | 16/615872 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6844 (20130101) C12Q 1/6874 (20130101) C12Q 2521/101 (20130101) C12Q 2521/507 (20130101) C12Q 2525/155 (20130101) C12Q 2535/122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530438 | Persson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Henrik H. J. Persson (Palo Alto, California); Roxana Jalili (Palo Alto, California); Joseph L. Horecka (Stanford, California); Ronald W. Davis (Palo Alto, California) |
| ABSTRACT | Provided herein is a circular proximity ligation assay in which proximity-probes are employed as bridges to connect two free oligonucleotides via a dual ligation event, resulting in the formation of a circle. The circles are then quantified by, e.g., qPCR. The addition of an extra oligonucleotide is believed to enhance specificity by decreasing the probability of random background ligation events. In addition, circle formation may have selective advantages, as uncircularized DNA can be removed by a simple exonuclease treatment and it has streamlined the workflow by eliminating preamplification prior to qPCR. |
| FILED | Tuesday, February 20, 2018 |
| APPL NO | 16/483383 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) Original (OR) Class C12Q 1/6851 (20130101) C12Q 2521/501 (20130101) C12Q 2523/307 (20130101) C12Q 2531/125 (20130101) C12Q 2537/162 (20130101) Enzymes C12Y 605/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530440 | Blainey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Paul Blainey (Cambridge, Massachusetts); Liyi Xu (Cambridge, Massachusetts) |
| ABSTRACT | The present invention relates to methods of quantifying, amplifying, or preparing nucleic acid molecules, where the methods involve contacting a sample to be tested with nucleic acid molecule amplification reaction components and a label to form a reaction sample. The methods further involve partitioning the reaction sample into droplets or a gel and allowing nucleic acid molecule amplification to occur. |
| FILED | Monday, November 04, 2019 |
| APPL NO | 16/673018 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6851 (20130101) Original (OR) Class C12Q 1/6851 (20130101) C12Q 1/6853 (20130101) C12Q 2531/119 (20130101) C12Q 2565/629 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530441 | He et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Chuan He (Chicago, Illinois); Ji Nie (Chicago, Illinois); Xiao-Long Cui (Chicago, Illinois) |
| ABSTRACT | The methods, compositions, and kits of the disclosure provide a novel approach for a whole genome, unbiased DNA analysis method that can be performed on limited amounts of DNA. can be used to analyze DNA to determine its modification status. Aspects of the disclosure relate to a method for amplifying bisulfite-treated deoxyribonucleic acid (DNA) molecules comprising: (a) ligating an adaptor to the DNA molecules, wherein the adaptor comprises a RNA polymerase promoter comprising bisulfite-protected cytosines; (b) treating the ligated DNA molecules with bisulfite; (c) hybridizing the bisulfite-treated DNA molecules with a primer; (d) extending the hybridized primer to make double stranded DNA; and (e) in vitro transcribing the double-stranded DNA to make RNA. |
| FILED | Friday, July 26, 2019 |
| APPL NO | 17/250365 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6865 (20130101) Original (OR) Class C12Q 1/6865 (20130101) C12Q 2523/115 (20130101) C12Q 2523/125 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530979 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Lihong Wang (Arcadia, California); Yang Li (Temple City, California); Tsz Wai Wong (Clear Water Bay Kowloon, China Hong Kong) |
| ABSTRACT | Multifocal photoacoustic imaging systems and methods that implement an ergodic relay to encode photoacoustic signals detected from a plurality of illuminated optical foci regions. |
| FILED | Wednesday, August 14, 2019 |
| APPL NO | 16/540936 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/1702 (20130101) Original (OR) Class G01N 2021/1706 (20130101) G01N 2201/105 (20130101) G01N 2201/0635 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11531029 | Marques, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania); YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Ernesto Torres De Azeved Marques, Jr. (Pittsburgh, Pennsylvania); Eduardo Nascimento (Pittsburgh, Pennsylvania); Albert Icksang Ko (New Haven, Connecticut); Donald S. Burke (Pittsburgh, Pennsylvania) |
| ABSTRACT | Disclosed are compositions and methods for the detection of a Flavivirus infection. In some embodiments, the method comprises detecting a recent Flavivirus infection by measuring the amount of anti-NS1 IgG3. In other embodiments, the method comprises detecting a prior Dengue virus infection in a subject previously immunized with a Dengue virus vaccine comprising one or more non-Dengue Flavivirus proteins. |
| FILED | Tuesday, May 08, 2018 |
| APPL NO | 16/611876 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/563 (20130101) G01N 33/6854 (20130101) G01N 33/56983 (20130101) Original (OR) Class G01N 2333/185 (20130101) G01N 2469/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11531126 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| INVENTOR(S) | Xin Li (Tucson, Arizona); Lars Furenlid (Tucson, Arizona) |
| ABSTRACT | The present invention provides a method of calibrating gamma-ray and photon counting detectors, including, but not limited to, monolithic crystal detectors. The method of the present invention is based on the observation that measurement of fan beam datasets allows the synthesis of collimated beam data to derive MDRFs by use of an algorithm that finds the common or intersecting data subsets of two or more orthogonal calibration datasets. This makes the calibration process very efficient while still allowing the full benefits of maximum-likelihood event-parameter estimation that incorporates the statistical nature of the light sensor measurements. |
| FILED | Friday, March 22, 2019 |
| APPL NO | 17/040456 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/202 (20130101) G01T 1/2018 (20130101) G01T 1/2964 (20130101) G01T 7/005 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11531207 | Nikolenko et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Volodymyr Nikolenko (New York, New York); Rafael Yuste (New York, New York); Brendon O. Watson (New York, New York); Darcy Peterka (Hoboken, New Jersey) |
| ABSTRACT | According to exemplary embodiments of the present disclosure, it is possible to provide method, system, arrangement, computer-accessible medium and device to stimulate individual neurons in brain slices in any arbitrary spatio-temporal pattern, using two-photon uncaging of photo-sensitive compounds such as MNI-glutamate and/or RuBi-Glutamate with beam multiplexing. Such exemplary method and device can have single-cell and three-dimensional precision. For example, by sequentially stimulating up to a thousand potential presynaptic neurons, it is possible to generate detailed functional maps of inputs to a cell. In addition, it is possible to combine this exemplary approach with two-photon calcium imaging in an all-optical method to image and manipulate circuit activity. Further exemplary embodiments of the present disclosure can include a light-weight, compact portable device providing for uses in a wide variety of applications. |
| FILED | Monday, December 18, 2017 |
| APPL NO | 15/845861 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/0622 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) G01N 2021/653 (20130101) G01N 2201/0221 (20130101) Optical Elements, Systems, or Apparatus G02B 21/0004 (20130101) G02B 27/46 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11531844 | Bharti et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Rockville, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Kapil Bharti (Potomac, Maryland); Nathan A. Hotaling (Washington, District of Columbia); Nicholas J. Schaub (Gaithersburg, Maryland); Carl G. Simon (Gaithersburg, Maryland) |
| ABSTRACT | A method is provided for non-invasively predicting characteristics of one or more cells and cell derivatives. The method includes training a machine learning model using at least one of a plurality of training cell images representing a plurality of cells and data identifying characteristics for the plurality of cells. The method further includes receiving at least one test cell image representing at least one test cell being evaluated, the at least one test cell image being acquired non-invasively and based on absorbance as an absolute measure of light, and providing the at least one test cell image to the trained machine learning model. Using machine learning based on the trained machine learning model, characteristics of the at least one test cell are predicted. The method further includes generating, by the trained machine learning model, release criteria for clinical preparations of cells based on the predicted characteristics of the at least one test cell. |
| FILED | Friday, March 15, 2019 |
| APPL NO | 16/981531 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6257 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/10056 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30024 (20130101) Image or Video Recognition or Understanding G06V 20/69 (20220101) G06V 20/695 (20220101) G06V 20/698 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11529054 | Mariano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Laura J. Mariano (Somerville, Massachusetts); John M. Irvine (Somerville, Massachusetts); Nirmal Keshava (Cambridge, Massachusetts) |
| ABSTRACT | A MRS (magnetic resonance spectroscopy or nuclear magnetic resonance NMR)-based PTSD (post-traumatic stress disorder) and mTBI (mild traumatic brain injury) diagnostic system and method uses MRS signals, already pre-processed by the MRS scanner software. The signals are collected in vivo from specific regions of the brain. A wavelet decomposition is applied to the MRS signals, and the amplitude of the wavelet coefficients and their location in the MRS signals are used as features for training diagnostic classifiers of disease states. These classifiers are identified through analysis of features of individuals whose health status is known. Once the classifiers are trained, patients can be diagnosed by using the same wavelet features extracted from in vivo MRS scans of their brain regions. |
| FILED | Wednesday, July 25, 2018 |
| APPL NO | 16/044874 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) Original (OR) Class A61B 5/055 (20130101) A61B 5/165 (20130101) A61B 5/726 (20130101) A61B 5/4064 (20130101) A61B 5/7267 (20130101) A61B 2576/026 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529131 | Chambers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | James A Chambers (Falls Church, Virginia); Kenneth P Seastedt (Alexandria, Virginia); Jocelyn Raymundo-Grinstead (JB Andrews, Maryland) |
| ABSTRACT | The systems and methods provided herein are directed to a surgical retractor which is optimized for production by additive manufacturing systems in situations where external medical supplies are interrupted or unavailable. |
| FILED | Thursday, February 27, 2020 |
| APPL NO | 16/803024 |
| ART UNIT | 3775 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/0206 (20130101) Original (OR) Class A61B 2017/00526 (20130101) A61B 2017/00915 (20130101) A61B 2017/00955 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529201 | Mondry et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| INVENTOR(S) | Jack Mondry (Edina, Minnesota); Shane Farritor (Lincoln, Nebraska); Eric Markvicka (Brush, Colorado); Thomas Frederick (Lincoln, Nebraska); Joe Bartels (Pittsburgh, Pennsylvania) |
| ABSTRACT | Disclosed herein are various medical device components, including components that can be incorporated into robotic and/or in vivo medical devices. Also disclosed are various medical devices for in vivo medical procedures. Included herein, for example, is a surgical robotic device having an elongate device body, a right robotic arm coupled to a right shoulder assembly, and a left robotic arm coupled to a left shoulder assembly. |
| FILED | Tuesday, March 05, 2019 |
| APPL NO | 16/293135 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/00234 (20130101) A61B 34/20 (20160201) A61B 34/30 (20160201) Original (OR) Class A61B 90/361 (20160201) A61B 2017/2906 (20130101) A61B 2034/302 (20160201) A61B 2034/2048 (20160201) A61B 2034/2051 (20160201) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0084 (20130101) B25J 9/0087 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529290 | Schulz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SIERRA NEVADA CORPORATION (Sparks, Nevada) |
| ASSIGNEE(S) | Sierra Nevada Corporation (Sparks, Nevada) |
| INVENTOR(S) | Karl Schulz (Sparks, Nevada); Richard Campbell (Sparks, Nevada); Emily Huang (Sparks, Nevada); Sarah Koh (Sparks, Nevada); Kurnhee Ma (Sparks, Nevada) |
| ABSTRACT | Mobile systems and methods are adapted to control and document prehospital patient care reports and communication of patient status to a receiving medical treatment facility. The systems and methods relate to systems and methods for managing, recording, and administering drugs such as narcotics in an ambulatory and/or emergency environment. |
| FILED | Friday, June 04, 2021 |
| APPL NO | 17/339588 |
| ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 50/22 (20160201) A61B 50/31 (20160201) Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 7/04 (20130101) A61J 7/0069 (20130101) Original (OR) Class A61J 7/0076 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/485 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 40/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529318 | Washington et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania); DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania); DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Kia M. Washington (Pittsburgh, Pennsylvania); William R. Wagner (Gibsonia, Pennsylvania); Michael Brandt Steketee (Wexford, Pennsylvania); Yolandi Van der Merwe (Pittsburgh, Pennsylvania); Xinzhu Gu (Jefferson Hills, Pennsylvania) |
| ABSTRACT | Devices for local delivery of tacrolimus or a derivative thereof are provided, wherein the devices comprise a polymeric matrix containing tacrolimus or a derivative thereof that provides for delayed and extended release of tacrolimus or a derivative thereof. The devices can locally deliver tacrolimus or a derivative thereof to injured nervous system tissue upon implantation in a subject. Thus, techniques for local delivery of tacrolimus or a derivative thereof and methods of treatment using such devices are also provided. |
| FILED | Monday, June 18, 2018 |
| APPL NO | 16/011281 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 9/7007 (20130101) Original (OR) Class A61K 31/436 (20130101) A61K 47/34 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529338 | Freeman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| ASSIGNEE(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| INVENTOR(S) | Michael Freeman (West Hollywood, California); Mirja Rotinen (Beverly Hills, California); Ramachandran Murali (Beverly Hills, California); Sungyong You (Los Angeles, California) |
| ABSTRACT | Provided herein are compositions and methods for treating, inhibiting and/or reducing the severity of neuroblastoma, small cell lung cancer (SCLC), large cell neuroendocrine cancer (LCNEC), large-cell carcinoma (LCC), squamous cell carcinoma (SqCC), and/or adenocarcinoma (AC) in subjects in need thereof. The methods include providing an agent that inhibits expression or activity of ONECUT2 and administering a therapeutically effective amount of the agent so as to treat, inhibit and/or reduce the severity of neuroblastoma, small cell lung cancer (SCLC), large cell neuroendocrine cancer (LCNEC), large-cell carcinoma (LCC), squamous cell carcinoma (SqCC), and/or adenocarcinoma (AC) in the subject. |
| FILED | Wednesday, August 22, 2018 |
| APPL NO | 16/640902 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/165 (20130101) A61K 31/343 (20130101) A61K 31/381 (20130101) A61K 31/397 (20130101) A61K 31/416 (20130101) A61K 31/445 (20130101) Original (OR) Class A61K 31/4164 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529447 | Stewart et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Ian Stewart (Lodi, California); Jonathan Sosnov (San Antonio, Texas); James Ross (Portland, Oregon) |
| ABSTRACT | A method of peritoneal removal of electrolytes and inflammatory mediators. The method begins with infusing a treatment solution into the peritoneal cavity of a patient by way of a catheter. The treatment solution is drained from the peritoneal cavity by way of the catheter. During the draining, the treatment solution is filtered for removing electrolytes and inflammatory mediators. |
| FILED | Friday, April 24, 2020 |
| APPL NO | 16/857782 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/28 (20130101) A61M 1/285 (20130101) Original (OR) Class A61M 1/287 (20130101) A61M 2202/0468 (20130101) A61M 2205/04 (20130101) A61M 2205/75 (20130101) Separation B01D 15/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529674 | Cassells et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Dewight R. Cassells (East Hartford, Connecticut); Alan C. Barron (Jupiter, Florida); John P. Rizzo (Vernon, Connecticut); Gordon Miller Reed (Plantsville, Connecticut); Tracy A. Propheter-Hinckley (Rocky Hill, Connecticut) |
| ABSTRACT | A refractory metal core (RMC) finishing method according to an exemplary aspect of the present disclosure includes, among other things, performing a plurality of finishing operations on a plurality of RMC samples, analyzing one or more properties of at least a portion of the plurality of RMC samples and selecting a combination of finishing operations for generating an RMC having desirable properties for manufacturing a part free from defects. |
| FILED | Wednesday, March 04, 2020 |
| APPL NO | 16/808529 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Foundry Moulding B22C 9/10 (20130101) B22C 9/18 (20130101) Original (OR) Class B22C 9/24 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/12 (20130101) F01D 5/187 (20130101) F01D 9/02 (20130101) Non-positive-displacement Pumps F04D 29/324 (20130101) F04D 29/542 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/10 (20130101) F05D 2230/21 (20130101) F05D 2240/81 (20130101) F05D 2260/204 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/303 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 19/04 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529771 | Matlack et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | Michael P. Matlack (St. Charles, Missouri); Dylan E. Polus (Glen Carbon, Illinois) |
| ABSTRACT | A method of heating a tool assembly includes the step of joining a first piece of the tool assembly with a second piece of the tool assembly via a first joint portion and a second joint portion. The method further includes the step of inserting a fastener through the first joint portion and the second joint portion of the tool assembly. The method further includes the step of applying heat to the tool assembly, wherein upon heating, interlock surfaces of the first joint portion and the second joint portion tighten against each other. |
| FILED | Monday, December 28, 2020 |
| APPL NO | 17/134762 |
| ART UNIT | 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 33/3842 (20130101) B29C 64/10 (20170801) B29C 70/342 (20130101) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530017 | Seeley |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Department of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Keyport, Washington) |
| INVENTOR(S) | Eric Seeley (Seabeck, Washington) |
| ABSTRACT | A field configurable autonomous vehicle includes modular elements and attachable components. The vehicle can be assembled from these modular elements and components to meet desired mission and performance characteristics without the need to purchase specially designed vehicles for each mission. The vehicle can include a module that enables the vehicle to be scuttled or destroyed. |
| FILED | Saturday, September 12, 2020 |
| APPL NO | 16/974041 |
| ART UNIT | 3617 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 85/00 (20200101) Original (OR) Class B63B 2017/0009 (20130101) Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/22 (20130101) B63G 2008/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530019 | Seeley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Office of Naval Research (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Keyport, Washington) |
| INVENTOR(S) | Eric Seeley (Seabeck, Washington); Logan Harris (Silverdale, Washington) |
| ABSTRACT | A field configurable autonomous vehicle includes modular elements and attachable components. The vehicle can be assembled from these modular elements and components to meet desired mission and performance characteristics without the need to purchase specially designed vehicles for each mission. The vehicle can include a modular propulsion system with magnetic drive. |
| FILED | Saturday, September 12, 2020 |
| APPL NO | 16/974044 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Vehicles for Use Both on Rail and on Road; Amphibious or Like Vehicles; Convertible Vehicles B60F 5/00 (20130101) Motor Vehicles; Trailers B62D 57/04 (20130101) Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/001 (20130101) B63G 8/08 (20130101) Original (OR) Class B63G 2008/002 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/31 (20130101) Dynamo-electric Machines H02K 21/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530026 | Bernhardt |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | Roger D. Bernhardt (St. Louis, Missouri) |
| ABSTRACT | The present disclosure provides a structural member for a vehicle. The structural member comprises a plurality of finned spar members interlocked with one another, wherein each of the finned spar members include a main body, a plurality of web members extending from a flange, a circuit board formed on the main body, and a bus bar formed on the main body, wherein a compartment is formed between adjacent web members, each compartment being sized to receive a battery. |
| FILED | Tuesday, June 11, 2019 |
| APPL NO | 16/437729 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 3/32 (20130101) Original (OR) Class B64C 3/185 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 41/00 (20130101) B64D 2221/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 50/20 (20210101) H01M 2220/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530167 | Tang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Xia Tang (West Hartford, Connecticut); Paul Sheedy (Bolton, Connecticut); Tania Bhatia Kashyap (West Hartford, Connecticut); Wayde R. Schmidt (Pomfret Center, Connecticut); Daniel G. Goberman (East Granby, Connecticut) |
| ABSTRACT | An article includes a ceramic-based substrate and a barrier layer on the ceramic-based substrate. The barrier layer includes a matrix of barium-magnesium alumino-silicate or SiO2, a dispersion of silicon oxycarbide particles in the matrix, and a dispersion of particles, of the other of barium-magnesium alumino-silicate or SiO2, in the matrix. |
| FILED | Monday, August 26, 2019 |
| APPL NO | 16/551036 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 9/005 (20130101) B32B 2255/20 (20130101) B32B 2264/102 (20130101) B32B 2307/308 (20130101) B32B 2307/7265 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/14 (20130101) C04B 35/195 (20130101) C04B 35/565 (20130101) C04B 35/5603 (20130101) C04B 41/87 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530203 | Piercey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Davin Glenn Piercey (Lafayette, Indiana); Matthew Lee Gettings (West Lafayette, Indiana) |
| ABSTRACT | The present disclosure relates to a novel tetrazole azasydnone, a method of making the novel tetrazole azasydnone, and a method of using the novel tetrazole azasydnone as a primary explosive. In one aspect, the novel tetrazole azasydnone has a structure of formula I: wherein A⊕ represents a cation with a 1+ charge. |
| FILED | Monday, June 07, 2021 |
| APPL NO | 17/340151 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 413/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530245 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Fuzhong Zhang (St. Louis, Missouri); Eugene Kim (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Fuzhong Zhang (St. Louis, Missouri); Eugene Kim (St. Louis, Missouri) |
| ABSTRACT | Mussels strongly adhere to a variety of surfaces by secreting byssal threads that contain mussel foot proteins (Mfps). Recombinant production of Mfps presents an attractive route for preparing advanced adhesive materials. Using synthetic biology strategies, Mfp5 together with Mfp5 oligomers containing two or three consecutive, covalently-linked Mfp5 sequences (named Mfp52 and Mfp53) were synthesized. Positive correlations were found between Mfp5 molecular weight and underwater adhesive properties, including adhesion force, adhesion work, protein layer thickness, and recovery distance. Dopa-modified Mfp53 displayed a high adhesion force (201±36 nN μm−1) and a high adhesion work (68±21 fJ μm−1) for 200 s cure times, higher than previously reported Mfp-mimetic adhesives. Results disclosed herein highlight the power of synthetic biology in producing biocompatible and highly adhesive Mfp-based materials. |
| FILED | Wednesday, August 28, 2019 |
| APPL NO | 16/554171 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/43504 (20130101) Original (OR) Class C07K 2319/20 (20130101) C07K 2319/92 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530246 | Khalil et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Ahmad S. Khalil (Lexington, Massachusetts); Wilson Wai Chun Wong (Brookline, Massachusetts); Divya Israni (Boston, Massachusetts); Huishan Li (Brookline, Massachusetts) |
| ABSTRACT | The technology described herein is directed to regulated synthetic gene expression systems. In one aspect described herein are synthetic transcription factors (synTFs) comprising a DNA binding domain, a transcriptional effector domain, and a regulator protein. In other aspects described herein are gene expression systems comprising said synTFs and methods of treating diseases and disorders using said synTFs. |
| FILED | Friday, May 15, 2020 |
| APPL NO | 16/875591 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/4702 (20130101) Original (OR) Class C07K 2319/09 (20130101) C07K 2319/20 (20130101) C07K 2319/50 (20130101) C07K 2319/81 (20130101) C07K 2319/715 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530328 | Walters et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio) |
| ASSIGNEE(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio) |
| INVENTOR(S) | David N. Walters (Slippery Rock, Pennsylvania); John R. Schneider (Allison Park, Pennsylvania) |
| ABSTRACT | Coating compositions are disclosed that include corrosion resisting particles such that the coating composition can exhibit corrosion resistance properties. Also disclosed are substrates at least partially coated with a coating deposited from such a composition and multi-component composite coatings, wherein at least one coating later is deposited from such a coating composition. Methods and apparatus for making ultrafine solid particles are also disclosed. |
| FILED | Monday, April 19, 2021 |
| APPL NO | 17/234459 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 283/006 (20130101) C08F 290/06 (20130101) C08F 299/06 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/672 (20130101) C08G 18/3206 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/22 (20130101) C08K 2003/222 (20130101) Compositions of Macromolecular Compounds C08L 23/26 (20130101) C08L 23/26 (20130101) C08L 27/00 (20130101) C08L 2666/04 (20130101) C08L 2666/20 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 4/06 (20130101) C09D 5/002 (20130101) C09D 5/084 (20130101) Original (OR) Class C09D 7/67 (20180101) C09D 123/26 (20130101) C09D 175/16 (20130101) C09D 175/16 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/258 (20150115) Y10T 428/31522 (20150401) Y10T 428/31529 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530404 | Farha et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Omar K. Farha (Glenview, Illinois); Peng Li (Chicago, Illinois); Justin A. Modica (Chicago, Illinois); Milan Mrksich (Hinsdale, Illinois); Joseph T. Hupp (Northfield, Illinois) |
| ABSTRACT | Enzyme-immobilizing MOFs and methods for their use in enzymatically catalyzed reactions are provided. The MOFs are channel-type MOFs that present a hierarchical pore structure comprising a first set of large channels sized for enzyme immobilization and a second set of smaller channels running alongside of the large channels that remain enzyme-free and allow for reactant delivery to the enzymes and product expulsion from the larger channels. |
| FILED | Thursday, May 25, 2017 |
| APPL NO | 16/306563 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus A62D 3/02 (20130101) A62D 2101/02 (20130101) A62D 2101/26 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) C12N 9/18 (20130101) C12N 11/02 (20130101) Original (OR) Class C12N 11/14 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 9/00 (20130101) Enzymes C12Y 301/01074 (20130101) C12Y 301/08002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530432 | Jewett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois); Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois); Cornell University (Ithaca, New York) |
| INVENTOR(S) | Michael Christopher Jewett (Evanston, Illinois); Jessica Carol Stark (Evanston, Illinois); Matthew P. DeLisa (Ithaca, New York); Thapakorn Jaroentomeechai (Ithaca, New York) |
| ABSTRACT | Disclosed are methods, systems, components, and compositions for cell-free synthesis of glycosylated carrier proteins. The glycosylated carrier proteins may be utilized in vaccines, including anti-bacterial vaccines. The glycosylated carrier proteins may include a bacterial polysaccharide conjugated to a carrier, which may be utilized to generate an immune response in an immunized host against the polysaccharide conjugated to the carrier. The glycosylated carrier proteins may be synthesized in cell-free glycoprotein synthesis (CFGpS) systems using prokaryote cell lysates that are enriched in components for glycoprotein synthesis such as oligosaccharyltransferases (OSTs) and lipid-linked oligosaccharides (LLOs) including OSTs and LLOs associated with synthesis of bacterial O antigens. |
| FILED | Tuesday, March 19, 2019 |
| APPL NO | 16/357820 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0258 (20130101) A61K 2039/6087 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1081 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/005 (20130101) Original (OR) Class Enzymes C12Y 204/99 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530644 | Kemmerer |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Geoffrey Robert Kemmerer (Port Hueneme, California) |
| ABSTRACT | An Ericsson cycle turbine engine. The Ericsson cycle turbine may comprise: a centrifugal gas compressor, shaft, at least one heat exchanger, and a reaction turbine. The centrifugal gas compressor may function as a spinning wheel trompe and may be fed with a gas-liquid mixture. The centrifugal gas compressor may separate a gas from the gas-liquid mixture and compress that gas via centrifugal acceleration. The shaft may couple to the downstream end of the centrifugal gas compressor and may have an annular space to permit the compressed gas to travel therein. The heat exchanger may introduce heat to the compressed gas, such that isothermal expansion is approached. The reaction turbine may couple to the downstream end of the shaft and may rotate the shaft when releasing the compressed gas against a plurality of vanes. The liquid may be mercury, oil, or water. The gas may be helium, air, argon, or ammonia. |
| FILED | Monday, November 29, 2021 |
| APPL NO | 17/536259 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/08 (20130101) F02C 7/08 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2210/13 (20130101) F05D 2260/10 (20130101) F05D 2260/213 (20130101) F05D 2260/22141 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530714 | McGann et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as Represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Shawn Kerry McGann (Ridgecrest, California); Nicholas McGaha (Ridgecrest, California) |
| ABSTRACT | A connector may couple to a non-cylindrical composite tubing having at least two lateral sides disposed in parallel and an open end. The connector may comprise first and second bonding plates adhered to an inner surface of the two lateral sides via an epoxy adhesive uniformly distributed. The first and second bonding plates may each have a distal lateral face defining a plurality of first threaded holes accessible at the open end of the composite tubing. The connector may also comprise an end plate having a plurality of first and second slotted holes disposed substantially in parallel and each aligned with an associating one of the first threaded holes. The connector may also comprise end plate fasteners loosely inserted through the first and second slotted holes and engaged with the first threaded holes. The end plate may also comprise one or more attachment points. |
| FILED | Friday, February 01, 2019 |
| APPL NO | 16/264987 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 65/48 (20130101) B29C 65/561 (20130101) B29C 66/022 (20130101) B29C 66/026 (20130101) B29C 66/5221 (20130101) Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 1/20 (20130101) Cleaning or Degreasing of Metallic Material by Chemical Methods Other Than Electrolysis C23G 1/00 (20130101) General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/3483 (20130101) Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 5/02 (20130101) Original (OR) Class F16B 9/01 (20180801) F16B 9/05 (20180801) F16B 11/006 (20130101) Technical Subjects Covered by Former US Classification Y10T 403/472 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530902 | Klann et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | Government of the United Slates, as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Shawn C. Klann (Warren, Michigan); Frederick C. Rickert, II (Royal Oak, Michigan); David B. Witherspoon (Port Huron, Michigan); William T. Hoffman (Howell, Michigan) |
| ABSTRACT | An explosive reactive armor (ERA) enclosure for an ERA tile includes a bottom and a plurality of sidewalls extending from the bottom, where the plurality of sidewalls are continuous with each other and with the bottom so as to define an internal volume. The plurality of sidewalls are formed from a fiber-reinforced composite material having a plurality of plies of fiber sheet material. Additionally, a sidewall seam defined by abutting edges of the first ply is offset from a sidewall seam defined by abutting edges of the second ply. Methods of manufacturing ERA enclosures, including applying wrap layers and forming attachment structures for securing the fiber-reinforced composite ERA enclosure to an armor element, are also described. The composite enclosure is inexpensive and lightweight and improves the dynamic capabilities of armored vehicles using such ERA tiles. |
| FILED | Thursday, July 15, 2021 |
| APPL NO | 17/376563 |
| ART UNIT | 1789 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 5/007 (20130101) Original (OR) Class F41H 5/013 (20130101) F41H 7/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530907 | Blazek et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Benjamin M. Blazek (Ridgecrest, California); Lee R. Hardt (Ridgecrest, California) |
| ABSTRACT | Embodiments are directed to direct impingement cook-off mitigation systems. As assembled, a munition fuzewell is torqued into the aft end of a munition. During a cook-off event, the expanding gases from the booster energetic will burn instead of detonating. The hot expanding booster gases are vented to the munition's main fill energetic causing the main fill energetic to burn concurrently with the booster energetic. The combined expanding gases from both the booster and main fill energetics are then vented through longitudinal vents. |
| FILED | Tuesday, February 23, 2021 |
| APPL NO | 17/182745 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 12/207 (20130101) F42B 39/14 (20130101) F42B 39/20 (20130101) Original (OR) Class Ammunition Fuzes; Arming or Safety Means Therefor F42C 19/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11531005 | Cooks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Robert Graham Cooks (West Lafayette, Indiana); Nicolás M. Morato (West Lafayette, Indiana); Dylan T. Holden (West Lafayette, Indiana) |
| ABSTRACT | The invention generally relates to high-throughput label-free enzymatic bioassays using desorption electrospray ionization-mass spectrometry (DESI-MS). |
| FILED | Wednesday, June 22, 2022 |
| APPL NO | 17/846923 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/64 (20130101) G01N 27/622 (20130101) Original (OR) Class G01N 27/626 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0409 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11531920 | Anahid et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Masoud Anahid (Simsbury, Connecticut); Tahany Ibrahim El-Wardany (Vernon, Connecticut); Sergei F. Burlatsky (West Hartford, Connecticut); William K. Tredway (Manchester, Connecticut) |
| ABSTRACT | A method of evaluating an additive manufacturing process includes receiving a set of additive manufacturing parameters and an additive manufacturing part design at an analysis module, receiving a set of random values at the analysis module, determining a probability distribution of stochastic flaws within a resultant additively manufactured article using at least one multidimensional space physics model, and categorizing the additive manufacturing part design as defect free when the probability distribution is below a predefined threshold. Each value in the set of random values corresponds to a distinct variable in a set of variables. Each variable in the set of variables at least partially defines at least one of an uncontrolled additive manufacturing parameter and an uncontrollable additive manufacturing parameter. |
| FILED | Monday, April 27, 2020 |
| APPL NO | 16/859349 |
| ART UNIT | 2115 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/4099 (20130101) G05B 2219/49023 (20130101) Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11532241 | Beaubien et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Aptima, Inc. (Woburn, Massachusetts) |
| ASSIGNEE(S) | Aptima, Inc. (Woburn, Massachusetts) |
| INVENTOR(S) | Jeffrey Beaubien (Londonderry, New Hampshire); John Feeney (Beavercreek, Ohio); William N. DePriest (Dayton, Ohio); Scott Pappada (Waterville, Ohio) |
| ABSTRACT | In one example embodiment of the invention, a simulation based training system is provided having a sensor that unobtrusively collects objective data for individuals and teams experiencing training content to determine the cognitive states of individuals and teams; time-synchronizes the various data streams; automatically determines granular and objective measures for individual cognitive load (CL) of individuals and teams; and automatically determines a cognitive load balance (CLB) and a relative cognitive load (RCL) measure in real or near-real time. Data is unobtrusively gathered through physiological or other activity sensors such as electroencephalogram (EEG) and electrocardiogram (ECG) sensors. Some embodiments are further configured to also include sociometric data in the determining cognitive load. Sociometric data may be obtained through the use of sociometric badges. Some embodiments further automatically customize the simulation content by automatically selecting content based on the CL of the individuals and teams. |
| FILED | Thursday, September 17, 2020 |
| APPL NO | 17/024325 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/16 (20130101) A61B 5/0245 (20130101) A61B 5/369 (20210101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 7/10 (20130101) G09B 9/00 (20130101) Original (OR) Class G09B 19/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11532355 | Ni et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California); University of Notre Dame du Lac (South Bend, Indiana) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); UNIVERSITY OF NOTRE DAME DU LAC (South Bend, Indiana) |
| INVENTOR(S) | Kai Ni (Notre Dame, Indiana); Suman Datta (South Bend, Indiana); Andrew Kummel (San Diego, California) |
| ABSTRACT | An N-bit non-volatile multi-level memory cell (MLC) can include a lower electrode and an upper electrode spaced above the lower electrode. N ferroelectric material layers can be vertically spaced apart from one another between the lower electrode and the upper electrode, wherein N is at least 2 and at least one dielectric material layer having a thickness of less than 20 nm can be located between the N ferroelectric material layers. |
| FILED | Friday, September 25, 2020 |
| APPL NO | 17/032847 |
| ART UNIT | 2825 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 11/221 (20130101) G11C 11/2275 (20130101) G11C 11/5657 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/11507 (20130101) H01L 28/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11532421 | Yao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Yuan Yao (Tarrytown, New York); Todd Edward Takken (Brewster, New York); Andrew Ferencz (Southborough, Massachusetts); Xin Zhang (Chappaqua, New York); Liam Daley McAuliffe (Yorktown Heights, New York) |
| ABSTRACT | Embodiment of the present invention includes a magnetic structure and a magnetic structure used in a direct current (DC) to DC energy converter. The magnetic structure has an E-core and a plate, with the plate positioned in contact or in near contact with the post surfaces of the E-core. The E-core has a base, a no-winding leg, a transformer leg, and an inductor leg. The no-winding leg, the transformer leg, and the inductor leg are perpendicular and magnetically in contact with the base. The plate is a flat slab with lateral dimensions generally larger than its thickness. The plate has a plate nose that overlaps a top no-winding leg surface of the no-winding leg with a no-winding gap area to form a no-winding gap with a no-winding gap reluctance. The plate also has a plate end that overlaps a top inductor leg surface of the inductor leg with an inductor gap area to form an inductor gap with an inductor gap reluctance. In some embodiments, e.g., where the duty cycle is less than 50 percent, the inductor gap reluctance will be designed to be less than the no-winding gap reluctance. In these cases, the majority of the magnetic flux that passes through the transformer leg will return through the inductor leg, instead of through the no-winding leg. The inductor and no-winding gap reluctances can he adjusted, so that the electromotive force applied to a charge passing through the inductor will partially cancel the electromotive force applied by the transformer secondary. The gap reluctance ratio can be defined, so that the difference in secondary and inductor electromotive forces is equal to the output voltage defined by an optimal no-ripple duty cycle. In this way no changing current is required through the inductor to create a dI/dt inductive voltage drop across the output inductor. Zero output current ripple is achieved. Various embodiments of the plate, plate shape, and no-winding leg are disclosed. These embodiments allow achieving a high ratio of no-winding gap reluctance to inductor gap reluctance, for practical, affordable magnetic material structures and aspect ratios. A high gap reluctance ratio enables zero output current ripple for the high transformer turns ratios that are needed to achieve high input to output voltage ratios. The embodiments therefore allow achieving low output current ripple for 48 V or higher input voltages, 1 V or lower output voltages, and high output currents. |
| FILED | Friday, February 12, 2021 |
| APPL NO | 17/174453 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/14733 (20130101) H01F 27/26 (20130101) Original (OR) Class H01F 27/28 (20130101) H01F 41/0206 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/33576 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11532478 | Anderson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Travis J. Anderson (Alexandria, Virginia); James C. Gallagher (Alexandria, Virginia); Marko J. Tadjer (Vienna, Virginia); Alan G. Jacobs (Arlington, Virginia); Boris N. Feigelson (Springfield, Virginia) |
| ABSTRACT | A method for activating implanted dopants and repairing damage to dopant-implanted GaN to form n-type or p-type GaN. A GaN substrate is implanted with n- or p-type ions and is subjected to a high-temperature anneal to activate the implanted dopants and to produce planar n- or p-type doped areas within the GaN having an activated dopant concentration of about 1018-1022 cm−3. An initial annealing at a temperature at which the GaN is stable at a predetermined process temperature for a predetermined time can be conducted before the high-temperature anneal. A thermally stable cap can be applied to the GaN substrate to suppress nitrogen evolution from the GaN surface during the high-temperature annealing step. The high-temperature annealing can be conducted under N2 pressure to increase the stability of the GaN. The annealing can be conducted using laser annealing or rapid thermal annealing (RTA). |
| FILED | Monday, November 08, 2021 |
| APPL NO | 17/520830 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/266 (20130101) H01L 21/3245 (20130101) H01L 21/26546 (20130101) Original (OR) Class H01L 21/28575 (20130101) H01L 29/36 (20130101) H01L 29/207 (20130101) H01L 29/452 (20130101) H01L 29/2003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11532778 | Venkatasubramanian et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Rama Venkatasubramanian (Cary, North Carolina); Luke E. Osborn (Baltimore, Maryland); Robert S. Armiger (Catonsville, Maryland); Meiyong Himmtann (Laurel, Maryland); Jonathan M. Pierce (North Eldersburg, Maryland) |
| ABSTRACT | A fast-rate thermoelectric device control system includes a fast-rate thermoelectric device, a sensor, and a controller. The fast-rate thermoelectric device includes a thermoelectric actuator array disposed on a wafer, and the thermoelectric actuator array includes a thin-film thermoelectric (TFTE) actuator that generates a heating and/or a cooling effect in response to an electrical current. The sensor is configured to measure a temperature associated with the heating or cooling effect and output a feedback signal indicative of the measured temperature. The controller is in communication with the fast-rate thermoelectric device and the sensor, and is configured to control the electrical current based on the feedback signal. |
| FILED | Tuesday, December 07, 2021 |
| APPL NO | 17/544391 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 21/02 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/16 (20130101) H01L 35/16 (20130101) H01L 35/30 (20130101) Original (OR) Class H01L 35/325 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11532942 | McCaig et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ASSETT, Inc. (Manassas, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert L McCaig (Marshall, Virginia); John McLaughlin (Manassas, Virginia) |
| ABSTRACT | This disclosure provides a battery management process and system including a battery including one or more batteries, a powered battery charging system connected to each of the one or more batteries to provide charge or charge balancing power to the one or more batteries, one or more battery sensors configured to monitor each batteries, a battery monitoring unit comprising a processor and memory in communication with the one or more battery sensors, the battery monitoring unit configured to initiate and conduct a charging or balancing process and monitor the battery for an out of tolerance condition, wherein if during charging or balancing an out of tolerance condition occurs in one or more batteries the battery monitoring unit interrupts the charging or balancing, process of the batteries by disconnecting the batteries with the out of tolerance condition from the charging system, the battery monitoring unit provides an alert to an operator to separately interrupt the charging or balancing process to the batteries with the out of tolerance condition via a separate operator controlled switch, and the battery monitoring unit interrupts power to the battery charging system providing power to the batteries with the out of tolerance condition. |
| FILED | Tuesday, June 07, 2022 |
| APPL NO | 17/805770 |
| ART UNIT | 2859 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 21/02 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0019 (20130101) H02J 7/0031 (20130101) Original (OR) Class H02J 7/0047 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11533042 | Daruwalla et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Anosh Daruwalla (Atlanta, Georgia); Farrokh Ayazi (Atlanta, Georgia) |
| ABSTRACT | Embodiments of the present disclosure relate generally to MEMS resonators. An exemplary MEMS resonator comprises a resonator beam having a length and a width. The length can be an integer multiple of the width. The integer multiple can be at least two. The resonator is configured to resonate at a frequency upon application of an input signal. The TCF of this resonator can be made close to zero, thus providing a temperature stable resonator. The exemplary MEMS resonator thereby has the advantages of high Q, low polarization voltage, low motional impedance and temperature stability of low frequency resonators while being able resonate at high frequencies of 30 MHz to 30 GHz. |
| FILED | Wednesday, January 16, 2019 |
| APPL NO | 16/249749 |
| ART UNIT | 2849 — Printing/Measuring and Testing |
| CURRENT CPC | Impedance Networks, e.g Resonant Circuits; Resonators H03H 3/0077 (20130101) H03H 9/02259 (20130101) H03H 9/2431 (20130101) H03H 9/2447 (20130101) Original (OR) Class H03H 9/02448 (20130101) H03H 2009/155 (20130101) H03H 2009/02291 (20130101) H03H 2009/02496 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11533067 | Guan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jariet Technologies, Inc. (Redondo Beach, California) |
| ASSIGNEE(S) | JARIET TECHNOLOGIES, INC. (Redondo Beach, California) |
| INVENTOR(S) | Claire Huinan Guan (Irvine, California); Craig A. Hornbuckle (Rolling Hills Estates, California) |
| ABSTRACT | A millimeter-wave phase array system may include massive heterodyne transceivers as its building elements. A transceiver of each element may include an IQ image rejection heterodyne transmitter and a receiver. Each transmitter may include a single DAC, a Tx I channel, and a Tx Q channel. Each receiver may include an Rx I channel, an Rx Q channel, and a single ADC. For Tx IQ image rejection calibration, amplitude and phase offsets are determined, using both the Tx I and Tx Q channels from a first element and using only one of the Rx I or Rx Q channel from a second element. The IQ channel imbalances are compensated using the offsets in analog domain. A similar procedure is used for Rx IQ image rejection calibration with alternated signal path enabling. A frequency response variation of an RF front end is detected with a single path Tx/Rx channel setup. |
| FILED | Friday, August 06, 2021 |
| APPL NO | 17/396500 |
| ART UNIT | 2631 — Digital Communications |
| CURRENT CPC | Transmission H04B 1/0014 (20130101) Original (OR) Class H04B 1/0483 (20130101) H04B 1/1607 (20130101) H04B 17/11 (20150115) H04B 17/21 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11533106 | Ahadian et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ULTRA COMMUNICATIONS, INC. (Vista, California) |
| ASSIGNEE(S) | ULTRA COMMUNICATIONS, INC. (Vista, California) |
| INVENTOR(S) | Joseph F. Ahadian (San Marcos, California); Vahid Nazer (San Marcos, California); Sandra Skendzic (Vista, California); Charles B. Kuznia (Encinitas, California); Richard J. Weiss (San Diego, California) |
| ABSTRACT | Methods and systems for automated health assessment of fiber optic links of a fiber optic communication system are described. Tables are used to describe the fiber optic links, including access addresses to communication modules used in the links. Telemetry data representative of operation of the communication modules can be read via the access addresses into a central station. OTDR/OFDR measurement data of fiber optic segments used in the links can be read via the access addresses into the central station. The telemetry and/or OTDR/OFDR measurement data can be used by the central station for comparison against reference data to assess health of the links. The communication modules locally and continuously capture the telemetry data to detect transient events that may be the result of tampering of the links. |
| FILED | Monday, May 16, 2022 |
| APPL NO | 17/663652 |
| ART UNIT | 2637 — Optical Communications |
| CURRENT CPC | Transmission H04B 10/071 (20130101) Original (OR) Class H04B 10/0793 (20130101) H04B 10/07955 (20130101) H04B 10/07957 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11533220 | Han et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | AT and T Intellectual Property I, L.P. (Atlanta, Georgia); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | AT and T Intellectual Property I, L.P. (Atlanta, Georgia); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Bo Han (Bridgewater, New Jersey); Vijay Gopalakrishnan (Edison, New Jersey); Marco Platania (Maplewood, New Jersey); Zhi-Li Zhang (Eden Prairie, Minnesota); Yang Zhang (St. Paul, Minnesota) |
| ABSTRACT | The concepts and technologies disclosed herein are directed to a network-assisted Raft consensus protocol, referred to herein as “NetRaft.” According to one aspect of the concepts and technologies disclosed herein, a system can include a plurality of servers operating in a server cluster, and a plurality of P4 switches corresponding to the plurality of servers. Each server of the plurality of servers can include a back-end that executes a complete Raft algorithm to perform leader election, log replication, and log commitment of a Raft consensus algorithm. Each P4 switch of the plurality of P4 switches can include a front-end that executes a partial Raft algorithm to perform the log replication and the log commitment of the Raft consensus algorithm. The back-end can maintain a complete state for responding to requests that cannot be fulfilled by the front-end. The requests can include read requests and/or write requests. |
| FILED | Monday, November 23, 2020 |
| APPL NO | 17/101280 |
| ART UNIT | 2114 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/0668 (20130101) Original (OR) Class H04L 45/64 (20130101) H04L 49/355 (20130101) H04L 67/1051 (20130101) H04L 67/1093 (20130101) H04L 67/1097 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11528988 | Noel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Alexis Noel (Atlanta, Georgia); David Hu (Atlanta, Georgia) |
| ABSTRACT | A brush-like device that adapts to tangles in hair and allows for easy removal of hair post-groom using uniquely shaped, anisotropic papillae not unlike those found on a feline tongue. |
| FILED | Wednesday, November 14, 2018 |
| APPL NO | 16/191382 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 13/00 (20130101) Brushes A46B 5/06 (20130101) A46B 9/023 (20130101) A46B 9/028 (20130101) Original (OR) Class A46B 2200/1093 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529201 | Mondry et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| INVENTOR(S) | Jack Mondry (Edina, Minnesota); Shane Farritor (Lincoln, Nebraska); Eric Markvicka (Brush, Colorado); Thomas Frederick (Lincoln, Nebraska); Joe Bartels (Pittsburgh, Pennsylvania) |
| ABSTRACT | Disclosed herein are various medical device components, including components that can be incorporated into robotic and/or in vivo medical devices. Also disclosed are various medical devices for in vivo medical procedures. Included herein, for example, is a surgical robotic device having an elongate device body, a right robotic arm coupled to a right shoulder assembly, and a left robotic arm coupled to a left shoulder assembly. |
| FILED | Tuesday, March 05, 2019 |
| APPL NO | 16/293135 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/00234 (20130101) A61B 34/20 (20160201) A61B 34/30 (20160201) Original (OR) Class A61B 90/361 (20160201) A61B 2017/2906 (20130101) A61B 2034/302 (20160201) A61B 2034/2048 (20160201) A61B 2034/2051 (20160201) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0084 (20130101) B25J 9/0087 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529205 | McKinley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Stephen McKinley (Berkeley, California); Animesh Garg (Berkeley, California); Sachin Patil (Burlingame, California); Susan M. L. Lim (Singapore, Singapore); Ken Goldberg (Mill Valley, California) |
| ABSTRACT | According to some embodiments of the invention, a surgical robot includes a robot arm having an end effector, the end effector comprising a needle assembly. The surgical robot further includes a robot control system operatively connected to the robot arm, and an end effector control system operatively connected to the end effector. The robot control system provides control signals for operation of the robot arm to move the end effector to selected positions relative to a subject. The end effector control system is configured to provide signals for operation of the end effector to at least one of inject material through the needle assembly to a selected location within the subject's body or extract material through the needle assembly from the selected location within the subject's body. |
| FILED | Thursday, June 23, 2016 |
| APPL NO | 15/738482 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 10/0233 (20130101) A61B 17/3211 (20130101) A61B 34/00 (20160201) A61B 34/30 (20160201) A61B 34/32 (20160201) A61B 34/35 (20160201) Original (OR) Class A61B 34/77 (20160201) A61B 90/00 (20160201) A61B 90/361 (20160201) A61B 2010/0208 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/20 (20130101) A61M 2205/50 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/1697 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/02 (20130101) Y10S 901/41 (20130101) Y10S 901/47 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529315 | Moon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Joong Ho Moon (Weston, Florida); Alfonso Barrios (Miami, Florida); Mario Milan Diaz (Miami, Florida) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida) |
| INVENTOR(S) | Joong Ho Moon (Weston, Florida); Alfonso Barrios (Miami, Florida); Mario Milan Diaz (Miami, Florida) |
| ABSTRACT | The subject invention provides materials and methods for intracellular deliver of molecules and/or therapeutic agents. The subject invention also provides methods for synthesizing polymeric systems and nanomaterials that enhance or assist the passage of molecules and/or therapeutic agents across biological membranes. The compound, polymer or nanoparticle of the subject invention comprises a modified guanidine moiety in a plurality of repeating units of a polymer or on the surface of a nanoparticle where the guanidine moiety comprises, for example, a carbamoyl or thiourea modification. The polymer or nanoparticle can be used in a cancer treatment formulation. |
| FILED | Wednesday, January 19, 2022 |
| APPL NO | 17/578709 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5115 (20130101) A61K 9/5138 (20130101) Original (OR) Class A61K 47/32 (20130101) A61K 47/34 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 43/00 (20180101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Heterocyclic Compounds C07D 491/048 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/125 (20130101) C08G 2261/1432 (20130101) C08G 2261/3342 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11529661 | Takata et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | KEYSTONE TOWER SYSTEMS, INC. (Denver, Colorado) |
| ASSIGNEE(S) | Keystone Tower Systems, Inc. (Denver, Colorado) |
| INVENTOR(S) | Rosalind K. Takata (Denver, Colorado); Loren Daniel Bridgers (Golden, Colorado); Eric D. Smith (Denver, Colorado) |
| ABSTRACT | Spiral forming devices, systems, and methods can be used to join edges of a of a stock material, in a curved configuration, along one or more joints to form tubular structures, such as conical and/or cylindrical structures (e.g., frusto-conical structures). A planar form of the stock material can be formed from a plurality planar sheets coupled to one another in an abutting relationship. By controlling relative orientation and shapes of the plurality of planar sheets forming the stock material and/or by controlling a position of a roll bender used to curve the planar form of the stock material into the curved configuration, the curved configuration of the stock material can be controlled through transitions between sheets to facilitate rolling the sheets to a desired diameter with a reduced likelihood of dimples or other errors and to facilitate fit up between adjacent sheets in the curved configuration. |
| FILED | Wednesday, September 30, 2020 |
| APPL NO | 17/038059 |
| ART UNIT | 3633 — Static Structures, Supports and Furniture |
| CURRENT CPC | Manufacture of Metal Sheets, Wire, Rods, Tubes or Profiles, Otherwise Than by Rolling; Auxiliary Operations Used in Connection With Metal-working Without Essentially Removing Material B21C 37/185 (20130101) Original (OR) Class Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 31/027 (20130101) Buildings or Like Structures for Particular Purposes; Swimming or Splash Baths or Pools; Masts; Fencing; Tents or Canopies, in General E04H 12/08 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/728 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530240 | Gianneschi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Nathan C. Gianneschi (Evanston, Illinois); Karen L. Christman (La Jolla, California); Andrea S. Carlini (Evanston, Illinois) |
| ABSTRACT | Cyclic peptide pro-gelator compositions, and methods of therapeutic use, which assemble into macromolecular hydrogel when administered through cleavage by endogenous enzymes upregulated at a site of tissue injury, such as a myocardial infarction. |
| FILED | Monday, June 11, 2018 |
| APPL NO | 16/620025 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0029 (20130101) A61K 38/10 (20130101) A61K 45/06 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 2300/412 (20130101) A61L 2300/414 (20130101) A61L 2400/06 (20130101) A61L 2430/20 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/00 (20130101) A61M 2210/125 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) Peptides C07K 7/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530246 | Khalil et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Ahmad S. Khalil (Lexington, Massachusetts); Wilson Wai Chun Wong (Brookline, Massachusetts); Divya Israni (Boston, Massachusetts); Huishan Li (Brookline, Massachusetts) |
| ABSTRACT | The technology described herein is directed to regulated synthetic gene expression systems. In one aspect described herein are synthetic transcription factors (synTFs) comprising a DNA binding domain, a transcriptional effector domain, and a regulator protein. In other aspects described herein are gene expression systems comprising said synTFs and methods of treating diseases and disorders using said synTFs. |
| FILED | Friday, May 15, 2020 |
| APPL NO | 16/875591 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/4702 (20130101) Original (OR) Class C07K 2319/09 (20130101) C07K 2319/20 (20130101) C07K 2319/50 (20130101) C07K 2319/81 (20130101) C07K 2319/715 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530278 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wilfred Chen (Hockessin, Delaware); Alexander A. Mitkas (Newark, Delaware) |
| ASSIGNEE(S) | University of Delaware (Newark, Delaware) |
| INVENTOR(S) | Wilfred Chen (Hockessin, Delaware); Alexander A. Mitkas (Newark, Delaware) |
| ABSTRACT | The present invention provides a method for controlling colocalization of two or more proteins in a cell. The method comprises expressing the proteins, scaffold RNA molecules having binding motifs for the proteins, and a trigger RNA molecule in the cell. In the presence of the trigger RNA molecule, a scaffold may be assembled (ON) by the scaffold RNA molecules via hybridization such that the proteins may be colocalized; or disassembled (OFF) such that the proteins may be separated and not colocalized. The proteins may provide a biological activity when colocalized or not colocalized. |
| FILED | Friday, January 24, 2020 |
| APPL NO | 16/751793 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 39/19 (20130101) Heterocyclic Compounds C07D 209/18 (20130101) C07D 403/14 (20130101) Peptides C07K 19/00 (20130101) Original (OR) Class C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 9/22 (20130101) C12N 15/111 (20130101) C12N 2310/531 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530288 | Taynton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mallinda (Denver, Colorado) |
| ASSIGNEE(S) | Mallinda (Denver, Colorado) |
| INVENTOR(S) | Philip Taynton (Morrison, Colorado); Yingdong Luo (San Jose, California); Heather Rubin (Arvada, Colorado); Denis Kissounko (Broomfield, Colorado); Samuel Loob (Parker, Colorado); Sarah Sadowski (Littleton, Colorado) |
| ABSTRACT | The present invention generally relates to covalent network polymers prepared from an imine-linked oligomer and an independent crosslinker comprising reactive moieties selected from the group consisting of epoxy, isocyanate, bismaleimide, sulfide, polyurethane, anhydride, polyester and combinations thereof. The covalent network polymers disclosed herein are advantageously made by anhydrous reactions, which enables the highest known glass transition temperatures to date for this class of materials. Further, the disclosed covalent network polymers can be formed in continuous processes, such as additive manufacturing processes that produce three-dimensional objects or roll-to-roll processes that produce covalent network polymer films or fully cured prepreg in various size formats. |
| FILED | Friday, September 06, 2019 |
| APPL NO | 16/635710 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 70/28 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 12/06 (20130101) Original (OR) Class Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/24 (20130101) C08J 5/18 (20130101) Compositions of Macromolecular Compounds C08L 61/20 (20130101) C08L 63/00 (20130101) C08L 2203/16 (20130101) C08L 2312/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530378 | Swoboda et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Ryan T. Swoboda (Orange Park, Florida); Yuhong Cao (Palo Alto, California); Sergio Leal-Ortiz (Stanford, California); Stefanie Rothkoetter (Stanford, California); Nicholas A. Melosh (Menlo Park, California) |
| ABSTRACT | Described herein are nanostraw well insert apparatuses (e.g., devices and systems) that include nanotubes extending through and out of a membrane so that a material can pass through the membrane from a fluid reservoir depot and into a cell grown onto the nanotubes when electrical energy (e.g., electroporation energy) is applied. In particular, the device, systems and methods described herein may be adapted for cell growth viability and transfection efficiency (e.g., >70%). These apparatuses may be readily integratable into cell culturing processes for improved transfection efficiency, intracellular transport, and cell viability. |
| FILED | Friday, June 09, 2017 |
| APPL NO | 16/302364 |
| ART UNIT | 1796 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/508 (20130101) B01L 2300/12 (20130101) B01L 2300/0609 (20130101) B01L 2300/0672 (20130101) B01L 2300/0832 (20130101) B01L 2400/0415 (20130101) Apparatus for Enzymology or Microbiology; C12M 25/02 (20130101) C12M 25/10 (20130101) C12M 29/16 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0075 (20130101) C12N 2531/00 (20130101) C12N 2533/00 (20130101) C12N 2539/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/56 (20130101) C23C 16/402 (20130101) C23C 16/403 (20130101) C23C 16/405 (20130101) C23C 16/45553 (20130101) C23C 16/45555 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530381 | Gerecht et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Sharon Gerecht (Severna Park, Maryland); Daniel Lewis (Riverside, Connecticut); Kyung Min Park (Baltimore, Maryland); T. S. Karin Eisinger (Philadelphia, Pennsylvania); M. Celeste Simon (Philadelphia, Pennsylvania) |
| ABSTRACT | The present invention describes methods for quantifying and analyzing cell migration and drug screening. Such methods include a gel (or a hydrogel) comprising a polymer, and cells that forms an oxygen gradient within the gel by controlling the balance of the diffusion of oxygen through the top of the gel and by the consumption of oxygen uptake by the cells. The migration of the cells is determined while the cells are grown in the gel of the present invention. |
| FILED | Wednesday, July 19, 2017 |
| APPL NO | 16/323882 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 41/46 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/5029 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530419 | Schultink et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Fortiphyte, Inc. (Berkeley, California) |
| ASSIGNEE(S) | Fortiphyte, Inc. (Berkeley, California) |
| INVENTOR(S) | Alexander Christiaan Schultink (Berkeley, California); Laura A. Wetzel (Berkeley, California) |
| ABSTRACT | The present disclosure provides an isolated, recombinant, or synthetic polynucleotide comprising a FIT1 protein, and homologs, fragments, and variations thereof. The disclosure further relates to transgenic plants, plant parts, and plant cells comprising one or more of these polynucleotides, and exhibit resistance or tolerance to a pathogen, such as Phakopsora pachyrhizi. The disclosure further relates to methods of genetically engineering a pathogen resistance or tolerance trait in a plant, plant part, or plant cell, comprising targeted gene editing of a FIT1 homolog, and plants produced therefrom. The disclosure further relates to methods for identifying new functional FIT1 genes and/or alleles thereof. |
| FILED | Wednesday, October 27, 2021 |
| APPL NO | 17/512329 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/902 (20130101) C12N 15/8282 (20130101) Original (OR) Class C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530432 | Jewett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois); Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois); Cornell University (Ithaca, New York) |
| INVENTOR(S) | Michael Christopher Jewett (Evanston, Illinois); Jessica Carol Stark (Evanston, Illinois); Matthew P. DeLisa (Ithaca, New York); Thapakorn Jaroentomeechai (Ithaca, New York) |
| ABSTRACT | Disclosed are methods, systems, components, and compositions for cell-free synthesis of glycosylated carrier proteins. The glycosylated carrier proteins may be utilized in vaccines, including anti-bacterial vaccines. The glycosylated carrier proteins may include a bacterial polysaccharide conjugated to a carrier, which may be utilized to generate an immune response in an immunized host against the polysaccharide conjugated to the carrier. The glycosylated carrier proteins may be synthesized in cell-free glycoprotein synthesis (CFGpS) systems using prokaryote cell lysates that are enriched in components for glycoprotein synthesis such as oligosaccharyltransferases (OSTs) and lipid-linked oligosaccharides (LLOs) including OSTs and LLOs associated with synthesis of bacterial O antigens. |
| FILED | Tuesday, March 19, 2019 |
| APPL NO | 16/357820 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0258 (20130101) A61K 2039/6087 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1081 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/005 (20130101) Original (OR) Class Enzymes C12Y 204/99 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530863 | Goldfarbmuren et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rebound Technologies, Inc. (Commerce City, Colorado) |
| ASSIGNEE(S) | Rebound Technologies, Inc. (Commerce City, Colorado) |
| INVENTOR(S) | Russell Goldfarbmuren (Denver, Colorado); Luke Erickson (Denver, Colorado) |
| ABSTRACT | Thermo-chemical recuperation systems, devices, and methods are provided in accordance with various embodiments. Embodiments may generally relate to the field of refrigeration and/or heat pumping. Within that field, some embodiments apply to the recuperation or recapturing of both thermal and chemical potential in a freeze point suppression cycle. Some embodiments include a method and/or system of thermo-chemical recuperation that includes creating a flow of ice and flowing a brine against the flow of the ice. Some embodiments manage the thermal and chemical potentials by mixing a dilute brine stream exiting an ice mixing vessel with an ice stream before it enters the ice mixing vessel. By controlling this mixing in a counter-flow or step-wise cross flow manner with sufficient steps, both the thermal and chemical potential of the dilute bine stream may be recuperated. |
| FILED | Sunday, June 20, 2021 |
| APPL NO | 17/352326 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Refrigerators; Cold Rooms; Ice-boxes; Cooling or Freezing Apparatus Not Otherwise Provided for F25D 5/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11531025 | Guo |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Ting Guo (Davis, California) |
| ABSTRACT | Provided herein are methods and materials that allow targeting and imaging of interactions between probes and targets. In some embodiments, the probes include nanoscale materials with embedded solutions that can be used to measure physical enhancement by materials under X-ray irradiation. In some embodiments, the methods of the present invention include delivering a probe material to a target that can have a delivered donor material. In some embodiments, methods of the present invention include irradiating the target and determining an optical change in the probe characteristic of a physical enhancement. |
| FILED | Friday, July 20, 2018 |
| APPL NO | 16/041107 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/223 (20130101) G01N 33/542 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11531027 | Ren et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
| INVENTOR(S) | Fan Ren (Gainesville, Florida); Stephen J. Pearton (Gainesville, Florida) |
| ABSTRACT | Various examples are provided for low cost disposable medical sensors fabricated on glass, paper or plastics, and applications thereof. In one example, a medical sensor includes a base structure comprising a functionalized sensing area; and a transistor disposed on the base structure adjacent to the functionalized sensing area. In another example, a medical sensor includes a base structure comprising a functionalized sensing area disposed on a first electrode pad and a reference sensing area disposed on a second electrode pad separated from the first electrode pad; and a transistor having a gate electrically coupled to the second electrode pad of the base structure. A gate pulse applied to the functionalized sensing can produce a drain current corresponding to an amount of a target present in a sample disposed on the base structure. |
| FILED | Friday, November 30, 2018 |
| APPL NO | 16/206493 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4145 (20130101) G01N 33/5438 (20130101) Original (OR) Class G01N 33/6887 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/778 (20130101) H01L 29/2003 (20130101) H01L 29/7786 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11531851 | Najarian et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Kayvan Najarian (Northville, Michigan); Jonathan Gryak (Ann Arbor, Michigan); Elyas Sabeti (Ypsilanti, Michigan); Joshua Drews (Ann Arbor, Michigan) |
| ABSTRACT | Computational algorithms integrate and analyze data to consider multiple interdependent, heterogeneous sources and forms of patient data, and using a classification model, provide new learning paradigms, including privileged learning and learning with uncertain clinical data, to determine patient status for conditions such as acute respiratory distress syndrome (ARDS) or non-ARDS. |
| FILED | Wednesday, February 05, 2020 |
| APPL NO | 16/782573 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6256 (20130101) G06K 9/6269 (20130101) Original (OR) Class G06K 9/6286 (20130101) Computer Systems Based on Specific Computational Models G06N 20/10 (20190101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11532381 | Reed et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ADVANCED POLYMER MONITORING TECHNOLOGIES, INC. (New Orleans, Louisiana); THE ADMINISTRATORS OF THE TULANE EDUCATION FUND (New Orleans, Louisiana) |
| ASSIGNEE(S) | ADVANCED POLYMER MONITORING TECHNOLOGIES, INC. (New Orleans, Louisiana); THE ADMINISTRATORS OF THE TULANE EDUCATION FUND (New Orleans, Louisiana) |
| INVENTOR(S) | Wayne Frederick Reed (New Orleans, Louisiana); Daniel J. Rees (New Orleans, Louisiana) |
| ABSTRACT | Method, device, and system for identifying a model-based time dependent light scattering signature that includes receiving an experimental time dependent light scattering signature comprising experimental data descriptive of an average molecular weight of protein components in a solution over time. The method further includes identifying an Ansatz for evaluating the experimental time dependent light scattering signature, the Ansatz being an initial model-based time dependent light scattering signature, the initial model-based time dependent light scattering signature identifying at least one key variable. The method also includes adjusting the at least one key variable in the initial model-based time dependent light scattering signature until a final model-based time dependent light scattering signature is identified. In some instances, the final model-based time dependent light scattering signature identifies at least one protein aggregation mechanism. |
| FILED | Thursday, January 12, 2017 |
| APPL NO | 16/070117 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2015/0038 (20130101) G01N 2015/0053 (20130101) G01N 2015/0092 (20130101) Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/20 (20190201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11532433 | Arnold et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | David P. Arnold (Gainesville, Florida); Ololade D. Oniku (Gainesville, Florida) |
| ABSTRACT | Various embodiments to mitigate the contamination of electroplated cobalt-platinum films on substrates are described. In one embodiment, a method of manufacture of a device includes depositing a diffusion barrier over a substrate, depositing a seed layer upon the diffusion barrier, and depositing a cobalt-platinum magnetic layer upon the seed layer. In a second embodiment, a method of manufacture of a device may include depositing a diffusion barrier over a substrate and depositing a cobalt-platinum magnetic layer upon the diffusion barrier. In a third embodiment, a method of manufacture of a device may include depositing an adhesion layer over a substrate, depositing a seed layer upon the adhesion layer, and depositing a cobalt-platinum magnetic layer over the seed layer. Based in part on these methods of manufacture, improvements in the interfaces between the layers can be achieved after annealing with substantial improvements in the magnetic properties of the cobalt-platinum magnetic layer. |
| FILED | Wednesday, February 26, 2020 |
| APPL NO | 16/801978 |
| ART UNIT | 2896 — Electrical Circuits and Systems |
| CURRENT CPC | Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/0038 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 10/30 (20130101) H01F 10/123 (20130101) H01F 41/32 (20130101) Original (OR) Class H01F 41/309 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/12 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49043 (20150115) Y10T 29/49044 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11532471 | Jarrold et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana) |
| ASSIGNEE(S) | The Trustees Of Indiana University (Bloomington, Indiana) |
| INVENTOR(S) | Martin F. Jarrold (Bloomington, Oregon); Staci N. Anthony (Grandview, Ohio); Benjamin E. Draper (Bloomington, Indiana) |
| ABSTRACT | An instrument for separating ions may include an ion source in a first pressure environment at a first pressure and configured to generate ions from a sample, an ion separation instrument, controlled to an instrument pressure that is less than the first pressure, and configured to separate ions as a function of at least one molecular characteristic and an interface, controlled to a second pressure less than the first pressure and greater than the instrument pressure, for transporting the generated ions from the first pressure environment into the ion separation instrument operating at the instrument pressure. The interface may include a sealed ion funnel defining an axial passageway therethrough, and an ion carpet sealed to the first ion funnel. A portion of the axial passageway tapers from a first cross-sectional area to a reduced cross-sectional area such that the tapered axial passageway defining a virtual jet disrupter therein. |
| FILED | Wednesday, September 08, 2021 |
| APPL NO | 17/468738 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/022 (20130101) H01J 49/24 (20130101) H01J 49/025 (20130101) H01J 49/066 (20130101) Original (OR) Class H01J 49/425 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11532770 | Ong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Shyue Ping Ong (La Jolla, California); Jungmin Ha (La Jolla, California); Zhenbin Wang (La Jolla, California); Joanna McKittrick (La Jolla, California); Won Bin Im (La Jolla, California); Yoon Hwa Kim (La Jolla, California) |
| ABSTRACT | A light emitting diode (LED) assembly includes an LED light source having a first light output with a characteristic spectrum and at least one phosphor through which the first light output passes. The phosphor includes the quaternary compound M-Li—Al—O, where M is Ba, Sr, or Ca, activated by Eu2+ or Ce3+. |
| FILED | Monday, October 15, 2018 |
| APPL NO | 16/755533 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 7/166 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/54 (20130101) C01P 2002/72 (20130101) C01P 2002/74 (20130101) C01P 2002/77 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/7721 (20130101) C09K 11/7734 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/502 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
11533096 — Reconfigurable, bi-directional, multi-band front end for a hybrid beamforming transceiver
| US 11533096 | Paramesh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Jeyanandh Paramesh (Pittsburgh, Pennsylvania); Susnata Mondal (Pittsburgh, Pennsylvania) |
| ABSTRACT | Designs and techniques to enhance power-efficiency and incorporate new features in millimeter-wave MIMO transceivers are described. A new mechanism for built-in dual-band, per-element self-interference cancellation (SIC) is introduced to enable multi-antenna frequency-division duplex (FDD) and full-duplex (FD) operation. Additionally, several innovative circuit concepts are introduced, including low-loss wideband antenna interface design, dual-band power combining PA, dual-band RF-SIC design, and bi-directional MIMO signal. |
| FILED | Wednesday, May 12, 2021 |
| APPL NO | 17/318757 |
| ART UNIT | 2632 — Digital Communications |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/523 (20130101) H01Q 3/38 (20130101) H01Q 21/0025 (20130101) Transmission H04B 1/40 (20130101) H04B 7/0413 (20130101) H04B 7/0617 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11533220 | Han et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | AT and T Intellectual Property I, L.P. (Atlanta, Georgia); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | AT and T Intellectual Property I, L.P. (Atlanta, Georgia); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Bo Han (Bridgewater, New Jersey); Vijay Gopalakrishnan (Edison, New Jersey); Marco Platania (Maplewood, New Jersey); Zhi-Li Zhang (Eden Prairie, Minnesota); Yang Zhang (St. Paul, Minnesota) |
| ABSTRACT | The concepts and technologies disclosed herein are directed to a network-assisted Raft consensus protocol, referred to herein as “NetRaft.” According to one aspect of the concepts and technologies disclosed herein, a system can include a plurality of servers operating in a server cluster, and a plurality of P4 switches corresponding to the plurality of servers. Each server of the plurality of servers can include a back-end that executes a complete Raft algorithm to perform leader election, log replication, and log commitment of a Raft consensus algorithm. Each P4 switch of the plurality of P4 switches can include a front-end that executes a partial Raft algorithm to perform the log replication and the log commitment of the Raft consensus algorithm. The back-end can maintain a complete state for responding to requests that cannot be fulfilled by the front-end. The requests can include read requests and/or write requests. |
| FILED | Monday, November 23, 2020 |
| APPL NO | 17/101280 |
| ART UNIT | 2114 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/0668 (20130101) Original (OR) Class H04L 45/64 (20130101) H04L 49/355 (20130101) H04L 67/1051 (20130101) H04L 67/1093 (20130101) H04L 67/1097 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11533593 | Krishnamoorthy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | New York University (New York, New York) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Saiprasanth Krishnamoorthy (Princeton, New Jersey); Vikram Kapila (West Orange, New Jersey) |
| ABSTRACT | An exemplary multi-robot system can include, for example, a first robot(s), which can include a communication arrangement and a sensor arrangement configured to detect a presence of an object(s) within a predetermined distance from the first robot(s), and determine a distance from the first robot(s) to the object(s), where the first robot(s) can broadcast a query to the object(s) using the communication arrangement, identify the object(s) as a second robot(s) or a non-robot based on a response received from the object(s). The sensor arrangement can be a Light Detection and Ranging (LiDAR) sensor arrangement. The LiDAR sensor arrangement can be a two-dimensional LiDAR sensor arrangement. |
| FILED | Wednesday, May 01, 2019 |
| APPL NO | 16/400422 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/162 (20130101) B25J 9/1664 (20130101) B25J 9/1676 (20130101) B25J 9/1697 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0289 (20130101) Wireless Communication Networks H04W 4/46 (20180201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11530232 | Kruger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Jacob S. Kruger (Arvada, Colorado); Gregg Tyler Beckham (Golden, Colorado); David Gregory Brandner (Golden, Colorado) |
| ABSTRACT | Disclosed herein are lignin valorization strategies that integrate thermochemical pretreatment strategies. Using methods disclosed herein, yields of greater than 40% of usable monomers are obtained from lignin in biomass. The monomers can be assimilated by strains of Pseudomonas putida. |
| FILED | Monday, November 16, 2020 |
| APPL NO | 17/099725 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Compounds of Unknown Constitution C07G 1/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530291 | Wilson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Thomas S. Wilson (San Leandro, California); Michael Keith Hearon (College Station, Texas); Jane P. Bearinger (Berwyn, Pennsylvania) |
| ABSTRACT | This invention relates to chemical polymer compositions, methods of synthesis, and fabrication methods for devices regarding polymers capable of displaying shape memory behavior (SMPs) and which can first be polymerized to a linear or branched polymeric structure, having thermoplastic properties, subsequently processed into a device through processes typical of polymer melts, solutions, and dispersions and then crossed linked to a shape memory thermoset polymer retaining the processed shape. |
| FILED | Monday, December 02, 2019 |
| APPL NO | 16/700116 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 45/0001 (20130101) B29C 48/00 (20190201) B29C 48/03 (20190201) B29C 51/00 (20130101) B29C 51/002 (20130101) B29C 61/06 (20130101) B29C 67/20 (20130101) B29C 71/02 (20130101) B29C 71/04 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2075/00 (20130101) B29K 2105/04 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/73 (20130101) C08G 18/83 (20130101) C08G 18/673 (20130101) C08G 18/675 (20130101) C08G 18/722 (20130101) C08G 18/758 (20130101) C08G 18/3206 (20130101) Original (OR) Class C08G 63/52 (20130101) C08G 2101/00 (20130101) C08G 2280/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530433 | Debnath et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Anik Debnath (Cambridge, Massachusetts); George Church (Cambridge, Massachusetts) |
| ABSTRACT | Provided herein, in some embodiments, are artificial secretion peptides capable of directing secretion from Lactobacillus for use, for example, in producing heterologous proteins, including therapeutic proteins. |
| FILED | Friday, October 19, 2018 |
| APPL NO | 16/757687 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/747 (20130101) A61K 2035/115 (20130101) Peptides C07K 14/605 (20130101) C07K 14/4723 (20130101) C07K 14/5428 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/746 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530458 | Hodge et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
| INVENTOR(S) | David B. Hodge (East Lansing, Michigan); Eric L. Hegg (East Lansing, Michigan); Zhenglun Li (Lansing, Michigan); Vaidyanathan Mathrubootham (Cary, North Carolina); Aditya Bhalla (Lansing, Michigan); Namita Bansal (Lansing, Michigan) |
| ABSTRACT | A homogeneous catalyst is provided comprising one or more metals; and at least two metal coordinating ligands wherein the homogeneous catalyst is a multi-ligand metal complex adapted for use with an oxidant in an oxidation reaction to catalytically pretreat lignocellulosic biomass. In one embodiment, the homogenous catalyst is copper (II) 2, 2′ bipyridine ethylenediamine (Cu(bpy)en). Related methods are also disclosed. |
| FILED | Friday, November 30, 2018 |
| APPL NO | 16/206848 |
| ART UNIT | 1738 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/183 (20130101) B01J 31/1805 (20130101) B01J 31/1815 (20130101) B01J 31/2243 (20130101) B01J 2231/70 (20130101) B01J 2531/16 (20130101) B01J 2531/72 (20130101) B01J 2531/842 (20130101) B01J 2531/845 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 1/08 (20130101) C07F 13/005 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 2201/00 (20130101) Saccharides Obtained From Natural Sources or by Hydrolysis of Naturally Occurring Disaccharides, Oligosaccharides or Polysaccharides C13K 1/02 (20130101) C13K 13/002 (20130101) Original (OR) Class Fibrous Raw Materials or Their Mechanical Treatment D21B 1/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530468 | Wu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | Margaret Wu (West Lebanon, New Hampshire); Ian Baker (Etna, New Hampshire) |
| ABSTRACT | The disclosure provides high strength high-entropy alloys with compositions (in atomic %) of FeaNibMncAldCreCf where 37-43 atomic %, b is 8-14 atomic %, c is 27-33 atomic %, d is 4-10 atomic %, e is 10-14 atomic %, and f is 0-2 atomic %. |
| FILED | Tuesday, June 11, 2019 |
| APPL NO | 17/251769 |
| ART UNIT | 1759 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Alloys C22C 30/00 (20130101) Original (OR) Class C22C 2202/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530703 | Nicholas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Air Squared, Inc. (Broomfield, Colorado) |
| ASSIGNEE(S) | Air Squared, Inc. (Broomfield, Colorado) |
| INVENTOR(S) | Nathan D. Nicholas (Westminster, Colorado); Bryce R. Shaffer (Denver, Colorado); John P. D. Wilson (Denver, Colorado) |
| ABSTRACT | A scroll device includes a fixed scroll with an idler shaft bearing, an orbiting scroll with another idler shaft bearing; and an eccentric idler shaft having first and second arms extending in opposite directions and ending at first and second ends, the first and second arms supported by the fixed scroll idler shaft bearing and the orbiting scroll idler shaft bearing, respectively. The eccentric idler shaft has a hollow core extending from the first end to the second end, with at least one channel extending through the first arm and enabling fluid communication between the hollow core and the at least one first bearing, and at least one second channel extending through the second arm and enabling fluid communication between the hollow core and the least one second bearing. |
| FILED | Wednesday, May 01, 2019 |
| APPL NO | 16/400921 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Rotary-piston or Oscillating-piston Machines or Engines F01C 1/0215 (20130101) F01C 19/125 (20130101) F01C 21/04 (20130101) Rotary-piston, or Oscillating-piston, Positive-displacement Machines for Liquids; Rotary-piston, or Oscillating-piston, Positive-displacement Pumps F04C 18/0215 (20130101) F04C 27/009 (20130101) F04C 29/023 (20130101) F04C 29/028 (20130101) Original (OR) Class F04C 2240/50 (20130101) F04C 2240/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11531117 | Brashar |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Connor Brashar (Albuquerque, New Mexico) |
| ABSTRACT | A system and method to distinguish spoofing signals from true GNSS signals is disclosed. One aspect of the present invention combines measuring GNSS carrier signals with measuring jitter in a vehicle's position via a low-cost inertial measurement unit (IMU) to distinguish spoofing signals from true GNSS signals. The present invention employs natural and/or artificial jitter of a vehicle, that, when combined with a tightly coupled inertial navigation system (INS), allows the receiver to distinguish the spoofing GNSS signal from the true GNSS signal. This spoofer survivability algorithm may be implemented, for example, in the software of a GNSS (or GPS) navigation system. |
| FILED | Wednesday, August 18, 2021 |
| APPL NO | 17/405478 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/47 (20130101) G01S 19/215 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11531124 | Kanatzidis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Mercouri G. Kanatzidis (Wilmette, Illinois); Bruce W. Wessels (Wilmette, Illinois); Zhifu Liu (Wilmette, Illinois); Wenwen Lin (Evanston, Illinois) |
| ABSTRACT | Methods and devices for detecting incident radiation, such as incident X-rays, gamma-rays, and/or alpha particle radiation are provided. The methods and devices use high purity, high quality single-crystals of inorganic semiconductor compounds, including solid solutions, having the formula AB2X5, where A represents Tl or In, B represents Sn or Pb, and X represents Br or I, as photoelectric materials. |
| FILED | Friday, July 21, 2017 |
| APPL NO | 16/318254 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/24 (20130101) G01T 1/241 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/085 (20130101) H01L 31/0264 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11532150 | Tohlen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Michael Aaron Tohlen (Lee's Summit, Missouri); Mitchell Hedges Morrow (Overland Park, Kansas) |
| ABSTRACT | A computer-implemented method comprises receiving a plurality of sampled data points, each data point including a y value and a t value; defining a plurality of bins; defining an array of elements; dividing the sampled data points into a plurality of sections; assigning a plurality of polynomial equations, one polynomial equation to each section, each polynomial equation having a waveform that fits the data points of the associated section; determining a plurality of section bin times, one section bin time for each bin in each section, each section bin time determined using the polynomial equation and indicating an amount of time that the waveform has values in the range of one of the bins; and adding the section bin time for each bin in each section to the histogram data in the array element pointed to by the number of the bin. |
| FILED | Tuesday, August 24, 2021 |
| APPL NO | 17/410030 |
| ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 17/12 (20130101) G06F 17/18 (20130101) G06F 17/40 (20130101) Image or Video Recognition or Understanding G06V 10/758 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11532421 | Yao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Yuan Yao (Tarrytown, New York); Todd Edward Takken (Brewster, New York); Andrew Ferencz (Southborough, Massachusetts); Xin Zhang (Chappaqua, New York); Liam Daley McAuliffe (Yorktown Heights, New York) |
| ABSTRACT | Embodiment of the present invention includes a magnetic structure and a magnetic structure used in a direct current (DC) to DC energy converter. The magnetic structure has an E-core and a plate, with the plate positioned in contact or in near contact with the post surfaces of the E-core. The E-core has a base, a no-winding leg, a transformer leg, and an inductor leg. The no-winding leg, the transformer leg, and the inductor leg are perpendicular and magnetically in contact with the base. The plate is a flat slab with lateral dimensions generally larger than its thickness. The plate has a plate nose that overlaps a top no-winding leg surface of the no-winding leg with a no-winding gap area to form a no-winding gap with a no-winding gap reluctance. The plate also has a plate end that overlaps a top inductor leg surface of the inductor leg with an inductor gap area to form an inductor gap with an inductor gap reluctance. In some embodiments, e.g., where the duty cycle is less than 50 percent, the inductor gap reluctance will be designed to be less than the no-winding gap reluctance. In these cases, the majority of the magnetic flux that passes through the transformer leg will return through the inductor leg, instead of through the no-winding leg. The inductor and no-winding gap reluctances can he adjusted, so that the electromotive force applied to a charge passing through the inductor will partially cancel the electromotive force applied by the transformer secondary. The gap reluctance ratio can be defined, so that the difference in secondary and inductor electromotive forces is equal to the output voltage defined by an optimal no-ripple duty cycle. In this way no changing current is required through the inductor to create a dI/dt inductive voltage drop across the output inductor. Zero output current ripple is achieved. Various embodiments of the plate, plate shape, and no-winding leg are disclosed. These embodiments allow achieving a high ratio of no-winding gap reluctance to inductor gap reluctance, for practical, affordable magnetic material structures and aspect ratios. A high gap reluctance ratio enables zero output current ripple for the high transformer turns ratios that are needed to achieve high input to output voltage ratios. The embodiments therefore allow achieving low output current ripple for 48 V or higher input voltages, 1 V or lower output voltages, and high output currents. |
| FILED | Friday, February 12, 2021 |
| APPL NO | 17/174453 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/14733 (20130101) H01F 27/26 (20130101) Original (OR) Class H01F 27/28 (20130101) H01F 41/0206 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/33576 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11532806 | Takeuchi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Foundation For The State University of New York (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Albany, New York) |
| INVENTOR(S) | Kenneth Takeuchi (South Setauket, New York); Esther Takeuchi (South Setauket, New York); Amy Marschilok (Setauket, New York) |
| ABSTRACT | Preparation, characterization, and an electrochemical study of Mg0.1V2O5 prepared by a novel sol-gel method with no high-temperature post-processing are disclosed. Cyclic voltammetry showed the material to be quasi-reversible, with improved kinetics in an acetonitrile-, relative to a carbonate-, based electrolyte. Galvanostatic test data under a C/10 discharge showed a delivered capacity >250 mAh/g over several cycles. Based on these results, a magnesium anode battery, as disclosed, would yield an average operating voltage ˜3.2 Volts with an energy density ˜800 mWh/g for the cathode material, making the newly synthesized material a viable cathode material for secondary magnesium batteries. |
| FILED | Friday, August 28, 2020 |
| APPL NO | 17/006682 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 31/00 (20130101) C01G 45/1221 (20130101) C01G 49/0036 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2004/03 (20130101) C01P 2006/12 (20130101) C01P 2006/40 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/48 (20130101) H01M 4/049 (20130101) Original (OR) Class H01M 4/50 (20130101) H01M 4/52 (20130101) H01M 4/5825 (20130101) H01M 10/052 (20130101) H01M 10/054 (20130101) H01M 10/0525 (20130101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11532818 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Lu Zhang (Lisle, Illinois); Zhangxing Shi (Westmont, Illinois); Andrew Jansen (Bolingbrook, Illinois); Stephen Trask (Batavia, Illinois) |
| ABSTRACT | A binder solution for manufacturing silicon-based anodes useful for lithium-ion electrochemical cells is described herein. The binder solution comprises a poly(carboxylic acid) binder dissolved in a mixed solvent system comprising an amide solvent of Formula I, as described herein, and a second solvent which can be water and/or an organic solvent. The binder preferably comprises poly(acrylic acid). The mixed solvent system comprises about 10 to about 99 vol % of the amide solvent of Formula I. The binder solution is utilized as a solvent for a slurry of silicon-containing particles for preparing a silicon-containing electrode. The slurries made with the mixed solvent systems have higher viscosity and are more stable than slurries containing the same concentrations of silicon particle, carbon particles, and binder in water as the sole solvent. |
| FILED | Friday, May 29, 2020 |
| APPL NO | 16/886908 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/02 (20130101) C08K 3/04 (20130101) C08K 2003/023 (20130101) C08K 2201/005 (20130101) C08K 2201/011 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 1/00 (20130101) C09D 7/20 (20180101) C09D 7/67 (20180101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/22 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/134 (20130101) H01M 4/386 (20130101) H01M 4/0404 (20130101) H01M 4/0471 (20130101) H01M 4/622 (20130101) Original (OR) Class H01M 4/1395 (20130101) H01M 10/0525 (20130101) H01M 2004/027 (20130101) H01M 2220/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11532830 | Narayan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Sri Narayan (Arcadia, California); Surya G. K. Prakash (Hacienda Heights, California); Bo Yang (Los Angeles, California); Lena Hoober-Burkhardt (Los Angeles, California); Sankarganesh Krishnamoorthy (Los Angeles, California) |
| ABSTRACT | A flow battery includes a positive electrode, a positive electrode electrolyte, a negative electrode, a negative electrode electrolyte, and a polymer electrolyte membrane interposed between the positive electrode and the negative electrode. The positive electrode electrolyte includes water and a first redox couple. The first redox couple includes a first organic compound which includes a first moiety in conjugation with a second moiety. The first organic compound is reduced during discharge while during charging the reduction product of the first organic compound is oxidized to the first organic compound. The negative electrode electrolyte includes water and a second redox couple. The second couple includes a second organic compound including a first moiety in conjugation with a second moiety. The reduction product of the second organic compound is oxidized to the second organic compound during discharge. |
| FILED | Monday, February 10, 2020 |
| APPL NO | 16/785715 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/08 (20130101) H01M 8/20 (20130101) H01M 8/188 (20130101) Original (OR) Class H01M 2250/10 (20130101) H01M 2300/0002 (20130101) H01M 2300/0082 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 90/10 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11532832 | Nie et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Zimin Nie (Richland, Washington); Wei Wang (Kennewick, Washington); Xiaoliang Wei (Richland, Washington); Bin Li (Richland, Washington); Jun Liu (Richland, Washington); Vincent L. Sprenkle (Richland, Washington) |
| ABSTRACT | All-vanadium sulfate redox flow battery systems have a catholyte and an anolyte comprising an aqueous supporting solution including chloride ions and phosphate ions. The aqueous supporting solution stabilizes and increases the solubility of vanadium species in the electrolyte, allowing an increased vanadium concentration over a desired operating temperature range. According to one example, the chloride ions are provided by MgCl2, and the phosphate ions are provided by (NH4)2HPO4. |
| FILED | Monday, April 27, 2020 |
| APPL NO | 16/859142 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/20 (20130101) Original (OR) Class H01M 8/188 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11533818 | Deng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Z. Daniel Deng (Richland, Washington); Jun Lu (Richland, Washington); Jayson J. Martinez (Richland, Washington); Aljon L. Salalila (Richland, Washington); Mitchell J. Myjak (Richland, Washington); Hongfei Hou (Richland, Washington) |
| ABSTRACT | Sensor assemblies are provided for use in modeling water systems. These sensor assemblies can be used as sensor fish. These assemblies can include a circuit board supporting processing circuitry components on either or both opposing component support surfaces of the circuit board and a housing above the circuit board and the components, with the housing being circular about the circuit board in at least one cross section, and wherein the supporting surfaces of the circuit board are substantially parallel with the plane of the housing in the one cross section. Methods for emulating interaction of entities within water systems are provided. The methods can include introducing a sensor assembly into a water system. The sensor assembly can include: a circuit board supporting processing circuitry components on either or both of opposing component support surfaces of the circuit board; a housing about the circuit board and the components, the housing being circular about the circuit board in at least one cross section; and wherein the support surfaces of the circuit board are substantially parallel with the plane of the housing in the one cross section. |
| FILED | Tuesday, March 12, 2019 |
| APPL NO | 16/351373 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 19/148 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/0047 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/1427 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11529201 | Mondry et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| INVENTOR(S) | Jack Mondry (Edina, Minnesota); Shane Farritor (Lincoln, Nebraska); Eric Markvicka (Brush, Colorado); Thomas Frederick (Lincoln, Nebraska); Joe Bartels (Pittsburgh, Pennsylvania) |
| ABSTRACT | Disclosed herein are various medical device components, including components that can be incorporated into robotic and/or in vivo medical devices. Also disclosed are various medical devices for in vivo medical procedures. Included herein, for example, is a surgical robotic device having an elongate device body, a right robotic arm coupled to a right shoulder assembly, and a left robotic arm coupled to a left shoulder assembly. |
| FILED | Tuesday, March 05, 2019 |
| APPL NO | 16/293135 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/00234 (20130101) A61B 34/20 (20160201) A61B 34/30 (20160201) Original (OR) Class A61B 90/361 (20160201) A61B 2017/2906 (20130101) A61B 2034/302 (20160201) A61B 2034/2048 (20160201) A61B 2034/2051 (20160201) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0084 (20130101) B25J 9/0087 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11531011 | Gershman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Daniel J. Gershman (Washington, District of Columbia); Levon Avanov (College Park, Maryland); Corey J. Tucker (Greenbelt, Maryland) |
| ABSTRACT | The present invention relates to an imaging device that includes a gating element which receives incident photons and releases pulsed electrons; a single microchannel-plate (MCP) which receives the pulsed electrons and amplifies the pulsed electrons as an amplified pulsed electron flux; a collection element which receives the amplified pulsed electron flux; a high-pass filter; and a gated integrator; wherein the high-pass filter element receives the amplified pulsed electron flux from the collection element and alternate current (AC) couples the amplified pulsed electron flux as a charge pulse to the gated integrator; and wherein the gating element and the gated integrator are time-synchronized to allow charge-integration only while the AC-coupled charge pulse is unipolar. A feedback loop can provide an auto-gating function. The imaging device can be used in night vision goggles or a mass spectrometer. |
| FILED | Monday, September 21, 2020 |
| APPL NO | 17/026587 |
| ART UNIT | 2879 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/72 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 31/507 (20130101) H01J 37/22 (20130101) H01J 43/246 (20130101) H01J 49/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11532296 | Koch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Lisa Danielle Koch (Bruswick, Ohio); Michael G. Jones (Newport News, Virginia); Peter J. Bonacuse (Lakewood, Ohio); Christopher J. Miller (Rocky River, Ohio); James Christopher Johnston (Seven Hills, Ohio); Maria A. Kuczmarski (Independence, Ohio) |
| ABSTRACT | Broadband acoustic absorbers may be capable providing good absorption performance between 0 and 3,000 Hz, and particularly below 1,000 Hz. Reeds may be incorporated in a single layer, multiple layers, or bundles. Such broadband acoustic absorbers may be applied for acoustic absorption in aircraft, spacecraft, residential and commercial buildings, vehicles, industrial environments, wind tunnels, or any other suitable environment or application where noise reduction is desired. |
| FILED | Wednesday, August 28, 2019 |
| APPL NO | 16/554191 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 11/168 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 11530945 | Key |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Wanda L. Key (Gainesville, Virginia) |
| ABSTRACT | A multi-dimensional measuring system is disclosed. The measuring system includes a dimensional measuring device that fits over an exterior portion of an item and provides reference measurements in three orthogonal directions. The measuring system also includes a camera to take an image of the item with the dimensional measuring placed thereon and a hardware processor that receives and processes the image to determine the dimensions of the item based upon the reference measurements of the dimensional measuring device. |
| FILED | Friday, March 06, 2020 |
| APPL NO | 16/811552 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 5/00 (20130101) G01B 11/02 (20130101) Weighing G01G 19/52 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11533177 | Bonnell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Clayton C Bonnell (Fairfax, Virginia); Kelley A Sullivan (Washington, District of Columbia) |
| ABSTRACT | Methods and systems for electronic document authentication are disclosed. In one aspect, a method of generating an electronic postmark includes receiving, via a server, a request message from an electronic network, the request message comprising request data including payload data and meta data, generating a timestamp in response to receiving the message, hashing the payload data to generate a payload hash, digitally signing the metadata, the payload hash, and the timestamp to generate a digital signature, generating a response message, the response message generated to comprise the metadata, the payload hash, the timestamp, and the digital signature; and transmitting the response message onto the electronic network. |
| FILED | Thursday, March 10, 2016 |
| APPL NO | 15/066945 |
| ART UNIT | 3685 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 1/00 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 20/102 (20130101) G06Q 20/3827 (20130101) G06Q 30/0283 (20130101) G06Q 50/32 (20130101) G06Q 2220/00 (20130101) G06Q 2250/05 (20130101) G06Q 2250/30 (20130101) G06Q 2250/60 (20130101) G06Q 2250/905 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11533178 | Bonnell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Clayton C. Bonnell (Fairfax, Virginia); Kelley A. Sullivan (Washington, District of Columbia) |
| ABSTRACT | Methods and systems for electronic document authentication are disclosed. In one aspect, a method of generating an electronic postmark includes receiving, via a server, a request message from an electronic network, the request message comprising request data including payload data and meta data, generating a timestamp in response to receiving the message, hashing the payload data to generate a payload hash, digitally signing the metadata, the payload hash, and the timestamp to generate a digital signature, generating a response message, the response message generated to comprise the metadata, the payload hash, the timestamp, and the digital signature; and transmitting the response message onto the electronic network. |
| FILED | Tuesday, November 20, 2018 |
| APPL NO | 16/197226 |
| ART UNIT | 3685 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 1/00 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 20/102 (20130101) G06Q 20/3827 (20130101) G06Q 30/0283 (20130101) G06Q 50/32 (20130101) G06Q 2220/00 (20130101) G06Q 2250/05 (20130101) G06Q 2250/30 (20130101) G06Q 2250/60 (20130101) G06Q 2250/905 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 11529335 | Schultz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| ASSIGNEE(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| INVENTOR(S) | Michael K. Schultz (Iowa City, Iowa); Somya Kapoor (Iowa City, Iowa); Douglas R. Spitz (Iowa City, Iowa) |
| ABSTRACT | The invention provides compositions and methods to treat a hyperproliferative disorder with a GSH synthesis inhibitor and an anti-cancer composition. |
| FILED | Friday, July 31, 2020 |
| APPL NO | 16/945323 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/66 (20130101) A61K 31/198 (20130101) A61K 31/437 (20130101) Original (OR) Class A61K 31/4706 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) Peptides C07K 16/2818 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11531737 | Boyd et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Daniel Boyd (Arlington, Virginia); Arun Vemury (North Bethesda, Maryland) |
| ABSTRACT | Systems, devices and methods for use in biometric identification are disclosed for use resolution of ambiguity as to what identity is being asserted and/or which reference identities are to be used to build a gallery for identification. In implementations, are described to resolve ambiguity and in particular situations in which a unique authoritative identifier is unavailable for use in locating relevant references to serve as the basis for biometric matching and identification. |
| FILED | Monday, October 07, 2019 |
| APPL NO | 16/594891 |
| ART UNIT | 3685 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Electric Digital Data Processing G06F 16/2455 (20190101) G06F 21/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 11529318 | Washington et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania); DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania); DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Kia M. Washington (Pittsburgh, Pennsylvania); William R. Wagner (Gibsonia, Pennsylvania); Michael Brandt Steketee (Wexford, Pennsylvania); Yolandi Van der Merwe (Pittsburgh, Pennsylvania); Xinzhu Gu (Jefferson Hills, Pennsylvania) |
| ABSTRACT | Devices for local delivery of tacrolimus or a derivative thereof are provided, wherein the devices comprise a polymeric matrix containing tacrolimus or a derivative thereof that provides for delayed and extended release of tacrolimus or a derivative thereof. The devices can locally deliver tacrolimus or a derivative thereof to injured nervous system tissue upon implantation in a subject. Thus, techniques for local delivery of tacrolimus or a derivative thereof and methods of treatment using such devices are also provided. |
| FILED | Monday, June 18, 2018 |
| APPL NO | 16/011281 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 9/7007 (20130101) Original (OR) Class A61K 31/436 (20130101) A61K 47/34 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11530424 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jia-Wang Wang (Tampa, Florida); Richard F. Lockey (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida); United States Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Jia-Wang Wang (Tampa, Florida); Richard F. Lockey (Tampa, Florida) |
| ABSTRACT | The clustered regularly interspaced short palindromic repeat (CRISPR) gene editing technique, based on the non-homologous end-joining (NHEJ) repair pathway, can efficiently generate gene knockouts of variably sizes. More precise genome editing, either the insertion or deletion of a desired fragment, can be done by combining the homology-directed-repair (HDR) pathway with CRISPR cleavage. HDR-mediated gene knock-in experiments are inefficient, with no reports of successful gene knock-in with DNA fragments larger than 4 kb. Targeted insertion of large DNA fragments (7.4 and 5.8 kb) into the genomes of mouse embryonic stem cells and zygotes, respectively, using the CRISPR/HDR technique without NHEJ inhibitors was performed and indicate that CRISPR/HDR without NHEJ inhibitors can result in highly efficient gene knock-in, equivalent to CRISPR/HDR with NHEJ inhibitors. Although NHEJ is the dominant repair pathway associated with CRISPR-mediated double-strand breaks (DSBs), and biallelic gene knock-ins are common, NHEJ and biallelic gene knock-ins were not detected. |
| FILED | Monday, September 30, 2019 |
| APPL NO | 16/587405 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) C12N 15/907 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11529307 | Firoozmand et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Hassan Firoozmand (Madison, Wisconsin); Richard Hartel (Madison, Wisconsin) |
| ABSTRACT | Colorant particles made from an insoluble protein-based substrate to which a dye is adsorbed are disclosed. The colorant particles are highly dispersible onto solid surfaces or within liquid systems, and thus can be used as substitutes for the alumina-based lake particles that are conventionally used as colorants in consumer products, such as food or beverage products, cosmetic products, pharmaceutical products, nutraceutical products, or toys. |
| FILED | Tuesday, November 13, 2018 |
| APPL NO | 16/762975 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 5/44 (20160801) A23L 5/46 (20160801) A23L 5/47 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 8/60 (20130101) A61K 8/64 (20130101) A61K 8/92 (20130101) A61K 8/99 (20130101) Original (OR) Class A61K 47/26 (20130101) A61K 47/44 (20130101) A61K 47/46 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 11532158 | Shah et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| INVENTOR(S) | Shishir K. Shah (Houston, Texas); Pranav Mantini (Houston, Texas) |
| ABSTRACT | Preferred embodiments described herein relate to a pipeline framework that allows for customized analytic processes to be performed on multiple streams of videos. An analytic takes data as input and performs a set of operations and transforms it into information. The methods and systems disclosed herein include a framework (1) that allows users to annotate and create variable datasets, (2) to train computer vision algorithms to create custom models to accomplish specific tasks, (3) to pipeline video data through various computer vision modules for preprocessing, pattern recognition, and statistical analytics to create custom analytics, and (4) to perform analysis using a scalable architecture that allows for running analytic pipelines on multiple streams of videos. |
| FILED | Thursday, October 15, 2020 |
| APPL NO | 17/071067 |
| ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6218 (20130101) G06K 9/6256 (20130101) Image or Video Recognition or Understanding G06V 20/41 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 11531099 | Bartone et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ohio University (Athens, Ohio) |
| ASSIGNEE(S) | Ohio University (Athens, Ohio) |
| INVENTOR(S) | Chris G. Bartone (Athens, Ohio); Anthony Milluzzi (Westlake, Ohio) |
| ABSTRACT | Systems and methods for detection and reporting of small targets to an operational area. Exemplary embodiments are presented to detect targets such as avian species, UAS, UAV, and drones, and transmit unique small target identifier information via data link, such as ADS-B, to an operational area. |
| FILED | Tuesday, January 23, 2018 |
| APPL NO | 16/479953 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/003 (20130101) G01S 7/411 (20130101) G01S 7/414 (20130101) G01S 13/86 (20130101) G01S 13/913 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Reconnaissance Office (NRO)
| US 11533062 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rockwell Collins, Inc. (Cedar Rapids, Iowa) |
| ASSIGNEE(S) | Rockwell Collins, Inc. (Cedar Rapids, Iowa) |
| INVENTOR(S) | Wenlu Chen (Clarksville, Maryland); Oliver S. King (Frederick, Maryland); Han Chi Hsieh (Gaithersburg, Maryland) |
| ABSTRACT | A non-uniform sampling pADC is disclosed. The pADC may include an optical pulse source configured to generate uniform optic pulses. The pADC may include a non-uniform sampling system. The non-uniform sampling system may include an inter-pulse timing modulation sub-system configured to convert the uniform optic pulses into non-uniform optic pulses. The non-uniform sampling system may include a timing control sub-system configured to control the timing of the optical pulse source. The pADC may include an optical modulator configured to modulate the non-uniform optical pulses. The pADC may include a photodetector configured to convert the modulated non-uniform optic pulses into electronic pulses. The pADC may include a pulse capture assembly configured to capture a pulse amplitude of the electronic pulses and generate sampled radio frequency output pulses. The pADC may include a quantizer configured to quantize the sampled radio frequency output pulses and generate digital radio frequency output signals. |
| FILED | Tuesday, June 29, 2021 |
| APPL NO | 17/361677 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 7/00 (20130101) Coding; Decoding; Code Conversion in General H03M 1/12 (20130101) H03M 7/008 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 11532421 | Yao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Yuan Yao (Tarrytown, New York); Todd Edward Takken (Brewster, New York); Andrew Ferencz (Southborough, Massachusetts); Xin Zhang (Chappaqua, New York); Liam Daley McAuliffe (Yorktown Heights, New York) |
| ABSTRACT | Embodiment of the present invention includes a magnetic structure and a magnetic structure used in a direct current (DC) to DC energy converter. The magnetic structure has an E-core and a plate, with the plate positioned in contact or in near contact with the post surfaces of the E-core. The E-core has a base, a no-winding leg, a transformer leg, and an inductor leg. The no-winding leg, the transformer leg, and the inductor leg are perpendicular and magnetically in contact with the base. The plate is a flat slab with lateral dimensions generally larger than its thickness. The plate has a plate nose that overlaps a top no-winding leg surface of the no-winding leg with a no-winding gap area to form a no-winding gap with a no-winding gap reluctance. The plate also has a plate end that overlaps a top inductor leg surface of the inductor leg with an inductor gap area to form an inductor gap with an inductor gap reluctance. In some embodiments, e.g., where the duty cycle is less than 50 percent, the inductor gap reluctance will be designed to be less than the no-winding gap reluctance. In these cases, the majority of the magnetic flux that passes through the transformer leg will return through the inductor leg, instead of through the no-winding leg. The inductor and no-winding gap reluctances can he adjusted, so that the electromotive force applied to a charge passing through the inductor will partially cancel the electromotive force applied by the transformer secondary. The gap reluctance ratio can be defined, so that the difference in secondary and inductor electromotive forces is equal to the output voltage defined by an optimal no-ripple duty cycle. In this way no changing current is required through the inductor to create a dI/dt inductive voltage drop across the output inductor. Zero output current ripple is achieved. Various embodiments of the plate, plate shape, and no-winding leg are disclosed. These embodiments allow achieving a high ratio of no-winding gap reluctance to inductor gap reluctance, for practical, affordable magnetic material structures and aspect ratios. A high gap reluctance ratio enables zero output current ripple for the high transformer turns ratios that are needed to achieve high input to output voltage ratios. The embodiments therefore allow achieving low output current ripple for 48 V or higher input voltages, 1 V or lower output voltages, and high output currents. |
| FILED | Friday, February 12, 2021 |
| APPL NO | 17/174453 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/14733 (20130101) H01F 27/26 (20130101) Original (OR) Class H01F 27/28 (20130101) H01F 41/0206 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/33576 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11529661 | Takata et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | KEYSTONE TOWER SYSTEMS, INC. (Denver, Colorado) |
| ASSIGNEE(S) | Keystone Tower Systems, Inc. (Denver, Colorado) |
| INVENTOR(S) | Rosalind K. Takata (Denver, Colorado); Loren Daniel Bridgers (Golden, Colorado); Eric D. Smith (Denver, Colorado) |
| ABSTRACT | Spiral forming devices, systems, and methods can be used to join edges of a of a stock material, in a curved configuration, along one or more joints to form tubular structures, such as conical and/or cylindrical structures (e.g., frusto-conical structures). A planar form of the stock material can be formed from a plurality planar sheets coupled to one another in an abutting relationship. By controlling relative orientation and shapes of the plurality of planar sheets forming the stock material and/or by controlling a position of a roll bender used to curve the planar form of the stock material into the curved configuration, the curved configuration of the stock material can be controlled through transitions between sheets to facilitate rolling the sheets to a desired diameter with a reduced likelihood of dimples or other errors and to facilitate fit up between adjacent sheets in the curved configuration. |
| FILED | Wednesday, September 30, 2020 |
| APPL NO | 17/038059 |
| ART UNIT | 3633 — Static Structures, Supports and Furniture |
| CURRENT CPC | Manufacture of Metal Sheets, Wire, Rods, Tubes or Profiles, Otherwise Than by Rolling; Auxiliary Operations Used in Connection With Metal-working Without Essentially Removing Material B21C 37/185 (20130101) Original (OR) Class Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 31/027 (20130101) Buildings or Like Structures for Particular Purposes; Swimming or Splash Baths or Pools; Masts; Fencing; Tents or Canopies, in General E04H 12/08 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/728 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 11530616 | Roberge |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Gary D. Roberge (Tolland, Connecticut) |
| ABSTRACT | A seal assembly for a gas turbine engine, including: a first finger seal assembly, the first finger seal assembly including two layers each being secured to each other, the two layers each having a plurality of slots that are offset from each other when the two layers of the first finger seal assembly are secured to each other; a second finger seal assembly, the second finger seal assembly including two layers each secured to each other, the two layers each having a plurality of slots that are offset from each other when the two layers of the second finger seal assembly are secured to each other; and an arc-shaped segment finger seal assembly located between the first finger seal assembly and the second finger seal assembly, the arc-shaped finger seal assembly including two layers each secured to each other, the two layers each having a plurality of slots that are offset from each other when the two layers of the arc-shaped finger seal assembly are secured to each other. |
| FILED | Wednesday, September 16, 2020 |
| APPL NO | 17/022650 |
| ART UNIT | 3675 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/005 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2230/60 (20130101) F05D 2240/57 (20130101) F05D 2250/71 (20130101) F05D 2300/175 (20130101) Pistons; Cylinders; Sealings F16J 15/022 (20130101) F16J 15/0887 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, December 20, 2022.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20221220.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page