FedInvent™ Patent Applications
Application Details for Thursday, January 12, 2023
This page was updated on Thursday, January 12, 2023 at 12:37 PM GMT
Department of Health and Human Services (HHS)
| US 20230007972 | Hassett et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kimberly Hassett (Medford, Massachusetts); Pradyot Nandi (Denver, Colorado); John Carpenter (Littleton, Colorado); Theodore Randolph (Niwot, Colorado) |
| ABSTRACT | The present invention relates generally to the field of immunogenic compositions containing volatile salts. In certain embodiments, compositions and methods disclosed herein relate to producing and using novel combinations to create frozen immunogenic agents bound to adjuvant having improved formulations and improved consistency of distribution of adjuvant for storage and subsequent delivery to a subject in need thereof. |
| FILED | Thursday, April 28, 2022 |
| APPL NO | 17/732224 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/19 (20130101) Original (OR) Class A61K 39/00 (20130101) A61K 39/39 (20130101) A61K 47/26 (20130101) A61K 2039/55505 (20130101) A61K 2039/55572 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230008026 | Gu et al. |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yuyang Gu (Durham, North Carolina); Tony Jun Huang (Durham, North Carolina) |
| ABSTRACT | The present disclosure provides for acoustofluidic centrifuge systems that can enrich and separate nanoparticles disposed in a fluid, such as liquid droplets, in a fast and efficient manner. Exemplary systems include a sound wave generator, such as a pair of slanted interdigitated transducers, and a containment boundary, such as a PDMS ring. The sound wave generator can produce surface acoustic waves that are capable of driving droplets to spin in a manner that can separate different sized particles into groups. In some embodiments, the acoustofluidic centrifuge system can include a plurality of containment boundaries in fluid communication with each other, allowing particles to separate between the containment boundaries. Methods of operating such systems, including methods of isolating different exosome subpopulations, are also disclosed. |
| FILED | Tuesday, April 12, 2022 |
| APPL NO | 17/719307 |
| CURRENT CPC | Separation B01D 21/283 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) Original (OR) Class B01L 2200/0652 (20130101) B01L 2400/0436 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4077 (20130101) G01N 21/6428 (20130101) G01N 2001/4094 (20130101) G01N 2021/6439 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230008266 | Zangi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Icahn School of Medicine at Mount Sinai (New York, New York) |
| ASSIGNEE(S) | Icahn School of Medicine at Mount Sinai (New York, New York) |
| INVENTOR(S) | Lior Zangi (New York, New York); Yoav Hadas (New York, New York); Nishat Sultana (New York, New York) |
| ABSTRACT | The present application relates to a nucleic acid molecule comprising a first nucleic acid sequence comprising at least a portion of a 5′ untranslated region (5′ UTR) of a carboxylesterase gene and a second nucleic acid sequence encoding a protein of interest, where the second nucleic acid sequence is heterologous to and operatively coupled to the first nucleic acid sequence. Also disclosed are methods of expressing a protein of interest in a target cell, methods of treating subject for cardiac ischemia or hepatic ischemia, and methods of identifying a nucleic acid sequence capable of selectively enhancing translation of a heterologous protein of interest in a target cell. |
| FILED | Friday, November 06, 2020 |
| APPL NO | 17/774912 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/16 (20180101) A61P 9/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/18 (20130101) C12N 15/11 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230008380 | OZDILEK et al. |
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| APPLICANT(S) | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia) |
| ASSIGNEE(S) | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia) |
| INVENTOR(S) | Ahmet OZDILEK (Athens, Georgia); Fikri Y. AVCI (Athens, Georgia) |
| ABSTRACT | The present disclosure provides isolated polynucleotides encoding a mature Mycobacterium tuberculosis protein selected from Ag85A, Ag85B, and Ag85C, where the protein does not include a signal for glycosylation, such as a N-glycosylation consensus sequon. Also disclosed are M. tuberculosis proteins selected from Ag85A, Ag85B, and Ag85C that do not include a signal for glycosylation, such as a N-glycosylation consensus sequon, and/or are not glycosylated, and methods for using the polynucleotides and proteins. |
| FILED | Tuesday, December 08, 2020 |
| APPL NO | 17/783379 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/04 (20130101) Original (OR) Class A61K 2039/53 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/06 (20180101) Peptides C07K 14/35 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230008544 | Dogan et al. |
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| APPLICANT(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
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| INVENTOR(S) | Meeshanthini Dogan (Iowa City, Iowa); Robert Philibert (Iowa City, Iowa) |
| ABSTRACT | Methods and compositions are provided for detecting a predisposition for cardiovascular disease in an individual. |
| FILED | Tuesday, July 05, 2022 |
| APPL NO | 17/857723 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/154 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230008650 | Balduini et al. |
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| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts); University of Pavia (Pavia, Italy) |
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| INVENTOR(S) | Alessandra Balduini (Pavia, Italy); David L. Kaplan (Concord, Massachusetts); Christian A. Di Buduo (Pavia, Italy) |
| ABSTRACT | Systems and methods for predicting patient-specific responses to the administration of medicaments that are indicated to modulate megakaryocyte differentiation, proplatelet formation, and/or platelet production are disclosed. The systems and methods can include a three-dimensional bone marrow model that is composed of silk fibroin sponges including a protein of the extracellular matrix, such as fibrinogen. The methods include creating patient-specific megakaryocyte progenitors (or progenitors thereof), seeding those progenitors into the model, introducing the medicament to the progenitors within one model, perfusing the model with a cell culture medium, maturing the progenitors, comparing platelet generation from the model including the medicament to a control model, and generating a report having a prediction of in vivo efficacy based on the comparison. |
| FILED | Monday, December 07, 2020 |
| APPL NO | 17/782989 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5073 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230008870 | Rowley et al. |
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| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah); Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jesse Worth Rowley (Salt Lake City, Utah); Matthew Rondina (Salt Lake City, Utah); Deepak Voora (Durham, North Carolina) |
| ABSTRACT | Disclosed herein are methods for making a transcriptome-wide expression profile of a biological sample and identifying biomarkers that can be used to diagnose, monitor the onset, monitor the progression, and assess the recovery of a disease in a subject. The biomarkers can also be used to establish and evaluate treatment regimens. |
| FILED | Friday, December 18, 2020 |
| APPL NO | 17/786397 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) Original (OR) Class C12Q 1/6837 (20130101) C12Q 1/6869 (20130101) C12Q 2600/158 (20130101) C12Q 2600/166 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5308 (20130101) G01N 2800/222 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230009208 | Italiano et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Brigham and Women’s Hospital, Inc. (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts); Vilnius University (Vilnius, Lithuania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph Italiano (Chestnut Hill, Massachusetts); Linas Mazutis (Boston, Massachusetts); Jonathan N. Thon (Cambridge, Massachusetts); David A. Weitz (Boston, Massachusetts) |
| ABSTRACT | A system and method are provided for harvesting target biological substances. The system includes a substrate and a first and second channel formed in the substrate. The channels longitudinally extending substantially parallel to each other. A series of gaps extend from the first channel to the second channel to create a fluid communication path passing between a series of columns with the columns being longitudinally separated by a predetermined separation distance. The system also includes a first source configured to selectively introduce into the first channel a first biological composition at a first channel flow rate and a second source configured to selectively introduce into the second channel a second biological composition at a second channel flow rate. The sources are configured to create a differential between the first and second channel flow rates to generate physiological shear rates along the second channel that are bounded within a predetermined range. |
| FILED | Friday, June 24, 2022 |
| APPL NO | 17/848523 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502746 (20130101) B01L 3/502753 (20130101) Original (OR) Class B01L 3/502776 (20130101) B01L 2200/0647 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) C12M 23/20 (20130101) C12M 25/02 (20130101) C12M 29/04 (20130101) C12M 29/10 (20130101) C12M 29/20 (20130101) C12M 41/36 (20130101) C12M 41/40 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/86 (20130101) G01N 33/491 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/25375 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230009323 | COMER et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts); The University of Vermont and State Agriculture College (Burlington, Vermont) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts); The University of Vermont and State Agriculture College (Burlington, Vermont) |
| INVENTOR(S) | Eamon COMER (Cambridge, Massachusetts); Bruno MELILLO (Cambridge, Massachusetts); Christopher D. HUSTON (Burlington, Vermont) |
| ABSTRACT | Cryptosporidium is a leading contributor to early childhood mortality, and fully effective treatment for this important infectious disease is lacking. A bicyclic azetidine compound series is disclosed having potent in vitro activity against all C. parvum isolates tested, comparable potencies against C. hominis and C. parvum, and cured cryptosporidiosis in highly susceptible immunosuppressed mice with once-daily dosing. |
| FILED | Friday, October 23, 2020 |
| APPL NO | 17/770264 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 33/00 (20180101) Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230009398 | SLUSHER et al. |
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| APPLICANT(S) | The John Hopkins University (Baltimore, Maryland); Ustav organické chemie a biochemie AV CR, v.v.i. (Czechia, Czech Republic) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Barbara SLUSHER (Kingsville, Maryland); Rana RAIS (Owings Mills, Maryland); Pavel MAJER (Sykesville, Maryland); Lukas TENORA (Czechia, Czech Republic); Katerina NOVOTNA (Czechia, Czech Republic); Jesse ALT (Nottingham, Maryland) |
| ABSTRACT | Glutamine antagonists and their use for treating oncological, immunological, and neurological diseases are disclosed. Also disclosed are methods for treating an oncological, immunological, infectious or neurological disease or disorder, the method comprising administering to a subject in need of treatment thereof a therapeutically effective amount of a glutamine antagonist of the disclosure or the pharmaceutical composition thereof. Also disclosed are methods of enhancing the effects of an immune checkpoint inhibitor, enabling a subject to respond to an immune checkpoint inhibitor, or enabling the toxicity or the dose or number of treatments with an immune checkpoint inhibitor to be reduced, comprising administering to a subject in need of treatment thereof a therapeutically effective amount of a glutamine antagonist of the disclosure or the pharmaceutical composition thereof, and an immune checkpoint inhibitor. Also disclosed are methods for treating an oncological, immunological, infectious or neurological disease or disorder that is refractory to checkpoint inhibitor therapy, the method comprising administering to a subject in need thereof, and having the refractory disease or disorder, a therapeutically effective amount of a glutamine antagonist of the disclosure or the pharmaceutical composition thereof. |
| FILED | Friday, October 05, 2018 |
| APPL NO | 16/754053 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 245/18 (20130101) C07C 271/22 (20130101) Original (OR) Class C07C 2603/18 (20170501) Heterocyclic Compounds C07D 209/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230009415 | Michael et al. |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
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| INVENTOR(S) | Katja Michael (El Paso, Texas); Igor C. Almeida (El Paso, Texas); Rosa A. Maldonado (El Paso, Texas); Alvaro Acosta-Serrano (El Paso, Texas); Alba A. Montoya (El Paso, Texas); Susana Portillo (El Paso, Texas) |
| ABSTRACT | Disclosed are neoglycoconjugates and/or glycosides containing glycan selected from Galpα1,3Galfβ, Galpα1,6Galpα1,3Galfβ, or Galpα1,3Galfβ1,3Manpα. Methods of using the glycosides and/or neoglycoconjugates as diagnostic or prognostic biomarkers, vaccines, treating or detecting parasitic diseases, such as cutaneous leishmaniasis are disclosed. |
| FILED | Friday, July 01, 2022 |
| APPL NO | 17/856241 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/42 (20130101) A61K 47/64 (20170801) A61K 47/65 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 33/02 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/569 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230009539 | Li et al. |
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| APPLICANT(S) | The Cleveland Clinic Foundation (Cleveland, Ohio) |
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| INVENTOR(S) | Xiaoxia Li (Cleveland, Ohio); Tomasz Herjan (Beachwood, Ohio); Lingzi Hong (Cleveland Heights, Ohio); Donna Marie Driscoll (Cleveland, Ohio); Caini Liu (Solon, Ohio) |
| ABSTRACT | Provided herein are compositions, systems, kits, and methods for treating IL-17a related diseases and conditions using an SBE nucleic acid sequence that binds a SEFIR domain of an ACT1 protein. |
| FILED | Monday, June 06, 2022 |
| APPL NO | 17/833323 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/06 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230009842 | Boehme et al. |
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| APPLICANT(S) | PowerTech Water Inc. (Lexington, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lindsay Boehme (Iowa City, Iowa); Cameron Lippert (Lexington, Kentucky); James Landon (Lexington, Kentucky); Alan Rassoolkhani (Lexington, Kentucky); Jeffrey Rentschler (Lexington, Kentucky) |
| ABSTRACT | The present invention is directed to an electrochemical device for at least partially removing or reducing a target ionic species from an aqueous solution using faradaic immobilization, the electrochemical device including at least one first electrode and at least one second electrode with different void fraction and surface area properties, due to differences in void fraction (also referred to as void ratio) of the at least one first and the at least one second electrode, water flows through an electrode with a high porosity, while the aqueous solution does not flow through an electrode with a low porosity. The asymmetry of the electrodes provides a desired voltage distribution across the device, which equates to a different voltage at each electrode, to control the speciation of the target ionic species at the anode and the cathode. |
| FILED | Wednesday, July 07, 2021 |
| APPL NO | 17/369346 |
| CURRENT CPC | Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor C25C 1/10 (20130101) Original (OR) Class C25C 7/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230009888 | DIMITROFF |
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| FUNDED BY |
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| APPLICANT(S) | CHARLES J. DIMITROFF (Coral Gables, Florida) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | CHARLES J. DIMITROFF (Coral Gables, Florida) |
| ABSTRACT | The subject invention provides novel methods for treating B cell malignancies, such as multiple myeloma, using a combination therapy. Said treatment in accordance with the subject invention comprises the administration of a B cell regulator, e.g., a galectin molecule, to a subject suffering from a B cell malignancy, and wherein said subject received, receives, or will receive a treatment with a conventional treatment for such B cell malignancy, e.g., immunotherapy. The administration of the galectin molecule boosts the expression of B cell specific antigens e.g., SLAMF7, on MM cells, thereby increasing the sensitivity of MM cells to anti-SLAMF7 Ab and therapeutic efficacy of Elotuzumab. |
| FILED | Friday, July 09, 2021 |
| APPL NO | 17/371770 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1732 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2803 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230010556 | Gu et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Zhen Gu (Los Angeles, California); Richard E. Wirz (Los Angeles, California); Guojun Chen (Los Angeles, California); Zhitong Chen (Los Angeles, California) |
| ABSTRACT | A cold atmospheric plasma (CAP)-mediated ICB therapy/delivery device are disclosed herein that employs a patch having microneedles that are used to deliver the CAP transdermally along with an immune checkpoint inhibitor for enhancing transdermal treatment efficacy. The hollow-structured microneedle patch can facilitate the transportation of CAP through the skin, causing tumor cell death. The release of cancer antigens then promotes the maturation of dendritic cells in the tumor-draining lymph nodes, subsequently initiating the T cell-mediated immune response. Anti-PDL1 antibody (aPDL1), an immune checkpoint inhibitor (or other immune checkpoint inhibitors), released from the microneedle patch (in some embodiments) further augments the anti-tumor immunity. The transdermal combinational CAP and ICB therapy inhibits tumor growth for both primary tumors as well as distant tumors, with prolonged survival in the tumor-bearing mice. Such results should translate to other species. |
| FILED | Thursday, December 10, 2020 |
| APPL NO | 17/779903 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0021 (20130101) A61K 9/0092 (20130101) A61K 39/3955 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/0015 (20130101) Original (OR) Class A61M 2037/003 (20130101) A61M 2037/0007 (20130101) A61M 2037/0023 (20130101) A61M 2037/0061 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/44 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230010637 | ZHOU et al. |
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| APPLICANT(S) | DONALDSON COMPANY, INC. (BLOOMINGTON, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | JINXIANG ZHOU (GREENVILLE, South Carolina); GRAHAM TEMPLES (GREENVILLE, South Carolina); BIN GUO (GREENVILLE, South Carolina) |
| ABSTRACT | Disclosed are methods for forming an activated membrane that can be further derivatized for use purifying plasmid DNA using hydrophobic interaction separation methods. Activated membrane and derivatized membrane formed by the methods are also described. HIC systems incorporating the derivatized membrane as described herein can exhibit a high plasmid DNA binding capacity and short residence times. |
| FILED | Thursday, May 12, 2022 |
| APPL NO | 17/742956 |
| CURRENT CPC | Polysaccharides; Derivatives Thereof C08B 1/003 (20130101) C08B 16/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 2301/02 (20130101) Compositions of Macromolecular Compounds C08L 1/02 (20130101) Original (OR) Class C08L 75/08 (20130101) C08L 79/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230010690 | Meller et al. |
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| FUNDED BY |
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| APPLICANT(S) | Morehouse School of Medicine (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert Meller (Covington, Georgia); Roger P. Simon (Atlanta, Georgia) |
| ABSTRACT | A method of distinguishing a subject with pre-clinical Alzheimer's disease from those with similar symptoms but other forms of dementia such as mild cognitive impairment. The blood RNA whole transcriptome profile of a subject with suspected pre-clinical Alzheimer's disease is obtained and analyzed against a reference blood RNA whole transcriptome profile from a subject with another form of dementia such as frontal temporal dementia, CADASIL or mild cognitive impairment (MCI). The blood RNA whole transcriptome profile includes the presence and quantitation of ncRNA. Methods to enhance treatment of epileptic seizures are also discussed. |
| FILED | Thursday, July 08, 2021 |
| APPL NO | 17/305480 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6809 (20130101) C12Q 1/6869 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/166 (20130101) C12Q 2600/178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230010733 | Pentecost et al. |
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| APPLICANT(S) | PHS SOLUTIONS LLC. (Ludlow Falls, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Randy J. Pentecost (Central City, Kentucky); Bryan S. Hall (Salyersville, Kentucky); Fred A. Sink (Ludlow Falls, Ohio) |
| ABSTRACT | A transitional water treatment wall for kidney dialysis is provided. The transitional wall includes several devices positioned on a mobile frame, the devices establishing fluid communication between a water source, pre-RO treatment equipment, and an RO system. The transitional water treatment wall also provides pressure and temperature control of the water being circulated. The mobile frame of the transitional water treatment wall includes wheels for providing ease of movement of the transitional water treatment wall. The mobile frame also limits space requirements for the various devices. The transitional wall also includes electrical outlets. |
| FILED | Friday, July 08, 2022 |
| APPL NO | 17/860732 |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/44 (20130101) Original (OR) Class C02F 2201/004 (20130101) C02F 2201/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230010803 | Balasubramanian et al. |
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| FUNDED BY |
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| APPLICANT(S) | Janssen Pharmaceutica NV (Beerse, Belgium); The UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sriram Balasubramanian (San Diego, California); Brendan Hodkinson (Spring House, Pennsylvania); Louise M. Staudt (Bethesda, Maryland); Wyndham H. Wilson (Menlo Park, California); George Wright (Rockville, Maryland) |
| ABSTRACT | Disclosed are methods for treating specific genetic subtypes of diffuse large B cell lymphoma using a combination of a BTK inhibitor and R-CHOP chemotherapy. The methods produce favorable event-free survival and overall survival rates among subjects exhibiting the genetic subtypes. |
| FILED | Thursday, June 30, 2022 |
| APPL NO | 17/854211 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/475 (20130101) A61K 31/519 (20130101) A61K 31/675 (20130101) A61K 31/704 (20130101) A61K 31/4985 (20130101) A61K 39/3955 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230011001 | ARONIS et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Konstantinos N. ARONIS (Baltimore, Maryland); Ronald D. BERGER (Baltimore, Maryland); Natalia A. TRAYANOVA (Baltimore, Maryland); Shijie ZHOU (Baltimore, Maryland); Harikrishna TANDRI (Ellicott City, Maryland) |
| ABSTRACT | A system and method are provided for a navigational feedback to a catheter during an arrhythmia ablation procedure. A set of electrocardiogram (ECG) signals of a patient's arrhythmia is recorded that correspond to an unknown target location to be ablated by the catheter. During the ablation procedure, pacing locations and ECG signals corresponding to the pacing locations are collected to derive a mathematical operator that maps a 12-dimensional displacement vector in the ECG space to a 3-dimensional (3D) vector in a physical space. This 3D vector corresponds to a direction and a distance that the catheter needs to be moved in order to reach the target location of the arrhythmia. |
| FILED | Wednesday, December 02, 2020 |
| APPL NO | 17/781503 |
| CURRENT CPC | Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/40 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230011378 | Duncan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Institute For Cancer Research d/b/a The Research Institute Of Fox Chase Cancer Center (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James S. Duncan (Philadelphia, Pennsylvania) |
| ABSTRACT | Pharmaceutical compositions comprising: one or more bromodomain and extra terminal domain (BET) proteolysis targeting chimera (PROTAC) (BET-PROTAC) therapeutic agents or one or more cyclin-dependent kinase 9 (CDK9) PROTAC (CDK9-PROTAC) therapeutic agents; and one or more kinase inhibitors, one or more KRAS inhibitors, or one or more autophagy inhibitors; and methods of treating cancer in a human patient by administering such pharmaceutical compositions are described herein. |
| FILED | Thursday, August 06, 2020 |
| APPL NO | 17/633307 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/551 (20130101) A61K 45/06 (20130101) A61K 47/55 (20170801) Original (OR) Class A61K 47/545 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230011622 | Tilly et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan L. Tilly (Windham, New Hampshire); Dori Woods (Londonderry, New Hampshire) |
| ABSTRACT | Disclosed are methods for increasing the fertilization rate of an oocyte in a granulosa cell-oocyte complex, and/or the success rate of in-vitro fertilization by using mitochondrial therapies. Also disclosed are methods of identifying compounds for fertility treatment. |
| FILED | Monday, February 22, 2021 |
| APPL NO | 17/801406 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0609 (20130101) C12N 15/873 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230011935 | Danielpour et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California); Children’s Hospital Medical Center (Cincinnati, Ohio) |
| ASSIGNEE(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California); Children’s Hospital Medical Center (Cincinnati, Ohio) |
| INVENTOR(S) | Moise Danielpour (Los Angeles, California); Fataneh Majlessipour (Los Angeles, California); Vivian Hwa (Cincinnati, Ohio) |
| ABSTRACT | The present invention describes methods for treating idiopathic short stature. Described herein are also methods of increasing a subject’s height. The methods involve administering an effective amount of a pan FGFR inhibitor or a selective FGFR inhibitor to the subject. An example of an FGRF inhibitor used in the methods described herein is erdafitinib. |
| FILED | Wednesday, December 09, 2020 |
| APPL NO | 17/782534 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/498 (20130101) Original (OR) Class A61K 47/54 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 43/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230012024 | Sullenger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bruce Sullenger (Durham, North Carolina); Elisabeth Tracy (Durham, North Carolina); Christopher Reed (Durham, North Carolina) |
| ABSTRACT | The present application provides for a method for controlling coagulation in a subject in need of extracorporeal membrane oxygenation. The method comprises administering an effective amount of an anticoagulant agent that directly inhibits one or more steps in a coagulation pathway to the subject, wherein the effective amount of the anticoagulant agent is capable of controlling coagulation during extra corporeal membrane oxygenation for a coagulation control time of at least 4 hours. |
| FILED | Friday, December 04, 2020 |
| APPL NO | 17/782848 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/60 (20170801) A61K 47/549 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) Original (OR) Class C12N 2310/16 (20130101) C12N 2310/351 (20130101) C12N 2320/51 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230012172 | ZHU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The George Washington University (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Wenge ZHU (Germantown, Maryland); Jing LI (Arlington, Virginia); Ruiqin WU (Sichuan, China PRC); Yiliang LI (Hebei, China PRC) |
| ABSTRACT | Embodiments of the instant disclosure relate to novel methods and compositions for treating tumors resistant to platinum-based chemotherapy. In certain embodiments, methods of treating tumors herein can include administering an effective amount of at least one ursolic acid derivative. In certain embodiments, methods of treating tumors herein can include administering an effective amount of at least one ursolic acid derivative in combination with at least one platinum-based chemotherapeutic separately or in a combination therapy. In some embodiments, methods of treating tumors disclosed herein can include screening and/or selecting a subject suitable for treatment on the basis of SENP1 tumor expression. In other embodiments, methods of treating tumors can include administering a composition disclosed herein to a subject, the composition having a combination of at least one ursolic acid derivative and at least one platinum-based chemotherapeutic. |
| FILED | Monday, August 22, 2022 |
| APPL NO | 17/892948 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/16 (20130101) A61K 31/22 (20130101) A61K 31/27 (20130101) Acyclic or Carbocyclic Compounds C07C 233/58 (20130101) Original (OR) Class C07C 235/26 (20130101) C07C 235/74 (20130101) C07C 235/88 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230012209 | Shin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joo-ho Shin (Seoul, South Korea); Areum Jo (Suwon, South Korea); Yunjong Lee (Choongchungbuk-Do, South Korea); Ted M. Dawson (Baltimore, Maryland); Valina L. Dawson (Baltimore, Maryland) |
| ABSTRACT | Methods of preventing or treating Parkinson's disease in subjects are described where drugs are administered to subjects in effective amounts to cause the farnesylation of PARIS and the enhanced expression of PGC-1α in the brain. These methods alleviate the effects of Parkinson's disease in subjects, in part, by preventing the loss of dopamine neurons. |
| FILED | Wednesday, February 23, 2022 |
| APPL NO | 17/678877 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/045 (20130101) Original (OR) Class A61K 31/443 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/566 (20130101) G01N 2333/70567 (20130101) G01N 2500/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230012213 | RADER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (GAINESVILLE, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | CHRISTOPH RADER (Jupiter, Florida); DOBEEN HWANG (Palm Beach Gardens, Florida) |
| ABSTRACT | The present invention provides modified catalytic antibody 38C2 with arylation of the reactive lysine residue (Lys99). The Lys99 residue is arylated with a heteroaryl methyl sulfonyl compound such as methylsulfone phenyl oxadiazole (MS-PODA). The invention also provides antibody conjugated agents (e.g., antibody drug conjugates) that contain an agent moiety that is site-specifically conjugated to 38C2 via a methyl sulfonyl compound. Further provided in the invention are methods of making the antibody conjugated agents and therapeutic applications of the antibody conjugated agents. |
| FILED | Thursday, October 15, 2020 |
| APPL NO | 17/770922 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6803 (20170801) Original (OR) Class A61K 47/6855 (20170801) A61K 47/6879 (20170801) Peptides C07K 16/32 (20130101) C07K 2317/24 (20130101) C07K 2317/31 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230012321 | ALLAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arvinas Operations, Inc. (New Haven, Connecticut) |
| ASSIGNEE(S) | Arvinas Operations, Inc. (New Haven, Connecticut) |
| INVENTOR(S) | Laura E.N. ALLAN (Dalkeith, United Kingdom); Chungpin Herman CHEN (Madison, Connecticut); Hanqing DONG (Madison, Connecticut); Robert J. DUGUID (Glenmont, New York); John A. GROSSO (Princeton Jct., New Jersey); Royal J. HASKELL, III (Durham, Connecticut); Casey Keith JAGER (Bend, Oregon); Venkata A. KATTUBOINA (Westford, Massachusetts); Aditya Mohan KAUSHAL (Bend, Oregon); Samuel Elliott KENNEDY (Bend, Oregon); Rhys LLOYD (North Lanarkshire, United Kingdom); Miranda Annell NEESER (Bend, Oregon); Yuping QIU (Princeton Junction, New Jersey); Hayley REECE (Dalkeith, United Kingdom); Maxwell Marco REEVE (Guilford, Connecticut); Joseph P. REO (Riegelsville, Pennsylvania); Jerod ROBERTSON (Robbinsville, New Jersey); Mohammad Mehdi ZAHEDI (Albany, New York) |
| ABSTRACT | The present disclosure relates to ultra-pure forms, polymorphs, amorphous forms, and formulations of N-[(1r,4r)-4-(3-chloro-4-cyanophenoxy)cyclohexyl]-6-[4-({4-[2-(2,6-dioxopiperidin-3-yl)-6-fluoro-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl]piperazin-1-yl}methyl)piperidin-1-yl]pyridazine-3-carboxamide, referred to herein as Compound A: The present disclosure also relates methods of manufacturing and purifying the same, as well as intermediates useful in the synthesis of Compound A. The ultra-pure forms, polymorphs, amorphous forms, and formulations of Compound A can be used as therapeutic agents for the treatment of various diseases and conditions such as cancer. |
| FILED | Thursday, May 06, 2021 |
| APPL NO | 17/313679 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 9/2009 (20130101) A61K 9/2018 (20130101) A61K 9/2054 (20130101) A61K 45/06 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/13 (20130101) Heterocyclic Compounds C07D 401/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230012362 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Taekyu Lee (Brentwood, Tennessee); Joseph R. Alvarado (Cleveland Heights, Ohio); Jianhua Tian (Nashville, Tennessee); Kenneth M. Meyers (Nashville, Tennessee); Changho Han (Nashville, Tennessee); Jonathan J. Mills (Nashville, Tennessee); Kevin B. Teuscher (Nashville, Tennessee); Shaun R. Stauffer (Brentwood, Tennessee); Stephen W. Fesik (Nashville, Tennessee) |
| ABSTRACT | Isoquinolinone compounds and derivatives inhibit WDRS and associated protein-protein interactions, and the compounds and their pharmaceutical compositions are useful for treating disorders and conditions in a subject, such as cancer cell proliferation. |
| FILED | Thursday, October 24, 2019 |
| APPL NO | 17/287492 |
| CURRENT CPC | Heterocyclic Compounds C07D 217/16 (20130101) C07D 401/06 (20130101) C07D 401/14 (20130101) Original (OR) Class C07D 405/14 (20130101) C07D 413/06 (20130101) C07D 413/14 (20130101) C07D 417/06 (20130101) C07D 417/14 (20130101) C07D 487/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230012420 | Chou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tsui-Fen Chou (San Marino, California); Shan Li (Pasadena, California); Feng Wang (Pasadena, California); Ting-Yu Wang (Pasadena, California) |
| ABSTRACT | Provided herein are methods and compositions for inhibiting p97, for the treatment of a motor neuron disease in a subject, or a symptom thereof. Upon treatment, the motor neuron disease, or a symptom thereof is reduced in the subject. |
| FILED | Friday, June 24, 2022 |
| APPL NO | 17/849075 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/69 (20130101) A61K 31/428 (20130101) A61K 31/496 (20130101) A61K 31/517 (20130101) A61K 31/519 (20130101) A61K 31/538 (20130101) A61K 31/4045 (20130101) A61K 31/4439 (20130101) A61K 31/7088 (20130101) A61K 38/465 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Peptides C07K 16/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/531 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230012465 | Han et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Bong-Gyoon Han (Castro Valley, California); Robert M. Glaeser (Berkeley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Bong-Gyoon Han (Castro Valley, California); Robert M. Glaeser (Berkeley, California) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus related to graphene. In one aspect, a method includes submerging a frame support in an etching solution that is contained in a container. A growth substrate, a graphene sheet disposed on the growth substrate, and a primary support disposed on the graphene sheet is placed on a surface of the etching solution. The growth substrate is dissolved in the etching solution to leave the graphene sheet and the primary support floating on a surface of the etching solution. The etching solution in the container is replaced with a washing solution. The washing solution is removed from the container so that the graphene sheet becomes disposed on the frame support. |
| FILED | Thursday, August 06, 2020 |
| APPL NO | 16/987173 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/194 (20170801) C01B 2204/02 (20130101) C01B 2204/04 (20130101) Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 1/08 (20130101) C23F 1/18 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 37/20 (20130101) H01J 2235/183 (20130101) H01J 2237/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20230007984 | SARKISIAN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sergei V. SARKISIAN (Midvale, None); Tommaso LENZI (Salt Lake City, Utah); Dante Amico Bennett ARCHANGELI (Salt Lake City, Utah) |
| ABSTRACT | An exoskeleton device that includes an artificial joint and a frame member extending from the artificial joint. The frame member is configured for extension over a limb of a user. The exoskeleton device also includes a self-aligning mechanism connected to the frame member. The self-aligning mechanism includes three passive degrees of freedom (pDOF) provided in a prismatic-revolute-revolute (PRR) configuration. The self-aligning mechanism also includes a limb attachment member configured for mechanically coupling to a portion of the limb of the user. |
| FILED | Friday, March 19, 2021 |
| APPL NO | 17/911526 |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/024 (20130101) A61H 1/0244 (20130101) A61H 3/00 (20130101) Original (OR) Class A61H 2003/007 (20130101) A61H 2201/123 (20130101) A61H 2201/164 (20130101) A61H 2201/165 (20130101) A61H 2201/1436 (20130101) A61H 2201/1673 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230008026 | Gu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yuyang Gu (Durham, North Carolina); Tony Jun Huang (Durham, North Carolina) |
| ABSTRACT | The present disclosure provides for acoustofluidic centrifuge systems that can enrich and separate nanoparticles disposed in a fluid, such as liquid droplets, in a fast and efficient manner. Exemplary systems include a sound wave generator, such as a pair of slanted interdigitated transducers, and a containment boundary, such as a PDMS ring. The sound wave generator can produce surface acoustic waves that are capable of driving droplets to spin in a manner that can separate different sized particles into groups. In some embodiments, the acoustofluidic centrifuge system can include a plurality of containment boundaries in fluid communication with each other, allowing particles to separate between the containment boundaries. Methods of operating such systems, including methods of isolating different exosome subpopulations, are also disclosed. |
| FILED | Tuesday, April 12, 2022 |
| APPL NO | 17/719307 |
| CURRENT CPC | Separation B01D 21/283 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) Original (OR) Class B01L 2200/0652 (20130101) B01L 2400/0436 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4077 (20130101) G01N 21/6428 (20130101) G01N 2001/4094 (20130101) G01N 2021/6439 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230008033 | Kellar |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Kevin Kellar (Bloomfield, Indiana) |
| ABSTRACT | Disclosed is an improved Sagnac interferometer sensor for inertial navigation and guidance systems (e.g., inertial measurement units (IMUs)) that affords a reduced area architecture. The sensor implements optical folding architectures and techniques to increase the optical path length of the Sagnac interferometer. The folding optical architecture increases the total optical path, which thereby increases the total phase difference between two counter-rotating optical beams in the Sagnac interferometer. The technique increases accuracy and durability of IMUs without the need for an increase in size, weight, and cost. |
| FILED | Friday, July 08, 2022 |
| APPL NO | 17/860174 |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/72 (20130101) Original (OR) Class G01C 21/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230008541 | Peled et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Noam Peled (Charlestown, Massachusetts); Steven Stufflebeam (Charlestown, Massachusetts) |
| ABSTRACT | A multi-modal visualization system (MMVS) is provided, which may be used to analyze and visualize bioimaging data, objects, and pointers, such as neuroimaging data, surgical tools, and pointing rods. MMVS can integrate multiple bioimaging modalities to visualize a plurality of bioimaging datasets simultaneously, such as anatomical bioimaging data and functional bioimaging data. |
| FILED | Wednesday, December 02, 2020 |
| APPL NO | 17/781858 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/10 (20160201) Original (OR) Class A61B 2034/104 (20160201) A61B 2034/105 (20160201) A61B 2090/365 (20160201) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4806 (20130101) Holographic Processes or Apparatus G03H 1/0005 (20130101) Image Data Processing or Generation, in General G06T 7/344 (20170101) G06T 19/006 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 5/02 (20130101) G09B 19/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230008590 | Hersam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark C. Hersam (Wilmette, Illinois); Qiucheng Li (Evanston, Illinois); Xiaolong Liu (Ithaca, New York); Eden B Aklile (Evanston, Illinois) |
| ABSTRACT | This invention in one aspect relates to a method of synthesizing a self-assembled mixed-dimensional heterostructure including 2D metallic borophene and 1D semiconducting armchair-oriented graphene nanoribbons (aGNRs). The method includes depositing boron on a substrate to grow borophene thereon at a substrate temperature in an ultrahigh vacuum (UHV) chamber; sequentially depositing 4,4″-dibromo-p-terphenyl on the borophene grown substrate at room temperature in the UHV chamber to form a composite structure; and controlling multi-step on-surface coupling reactions of the composite structure to self-assemble a borophene/graphene nanoribbon mixed-dimensional heterostructure. The borophene/aGNR lateral heterointerfaces are structurally and electronically abrupt, thus demonstrating atomically well-defined metal-semiconductor heterojunctions. |
| FILED | Tuesday, April 19, 2022 |
| APPL NO | 17/723595 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/184 (20170801) Original (OR) Class C01B 35/023 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02425 (20130101) H01L 21/02491 (20130101) H01L 21/02499 (20130101) H01L 21/02516 (20130101) H01L 21/02527 (20130101) H01L 21/02603 (20130101) H01L 21/02617 (20130101) H01L 21/28506 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230008708 | Karnani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army DEVCOM, Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sunny V. Karnani (West Lafayette, Indiana); Christopher M. Waits (Edgewater, Maryland) |
| ABSTRACT | A recirculating micro-combustor device and a method of formation includes an array of reactors contacting each other. Each reactor includes a front wall; an end wall oppositely positioned to the front wall; a pair of edge walls connecting the front wall to the end wall; an inlet port positioned in the front wall; a pair of outlet ports positioned in the front wall; and a combustion chamber connected to the inlet port and positioned between the front wall and the end wall. The combustion chamber includes a pair of inner walls defining a first area to accommodate a chemical combustion therein, and a pair of second areas to accommodate an exhaust of a reaction of the chemical combustion. The pair of second areas connect to the pair of outlet ports. Adjacent edge walls of adjacent reactors directly contact each other to form the array of reactors. |
| FILED | Thursday, July 08, 2021 |
| APPL NO | 17/369999 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0093 (20130101) B01J 2219/00797 (20130101) B01J 2219/00822 (20130101) B01J 2219/00873 (20130101) Methods or apparatus for combustion using fluid fuel or Solid Fuel Suspended In Air F23C 3/002 (20130101) Original (OR) Class F23C 13/00 (20130101) F23C 2900/03001 (20130101) F23C 2900/03009 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230008773 | JOHNSON et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Terumo BCT Biotechnologies, LLC (Lakewood, Colorado) |
| ASSIGNEE(S) | Terumo BCT Biotechnologies, LLC (Lakewood, Colorado) |
| INVENTOR(S) | Nathaniel T. JOHNSON (Highlands Ranch, Colorado); Rylan A. SUMMIT (Denver, Colorado); Dennis A. BRIDGES (Arvada, Colorado); Dennis J. HLAVINKA (Arvada, Colorado); Kestas P. PARAKININKAS (Englewood, Colorado); Kirk L. WEIMER (Green Valley, Arizona); Michael Lawrence GLOVER (Lakewood, Colorado); Alexander Du NGUYEN (Denver, Colorado); Margaret V. KWIAT (Evergreen, Colorado) |
| ABSTRACT | Provided is a gas fill fixture for use in lyophilization, a related system and method. The gas fill fixture includes a chassis, fill indicator and a lid, such that the chassis and lid together form a cavity for receiving a flexible lyophilization container. The system includes a lyophilization container, a lyophilizer and a gas fill fixture incorporating a chassis, a fill indicator and a lid. The method includes process steps for using the system to lyophilize a fluid. |
| FILED | Tuesday, September 06, 2022 |
| APPL NO | 17/903506 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0263 (20130101) A01N 1/0284 (20130101) A01N 1/0289 (20130101) Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 1/10 (20130101) A61J 1/1468 (20150501) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/0277 (20140204) A61M 2202/0415 (20130101) A61M 2205/584 (20130101) A61M 2205/3389 (20130101) Drying Solid Materials or Objects by Removing Liquid Therefrom F26B 5/06 (20130101) Original (OR) Class F26B 21/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230008918 | JANG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Junsu JANG (Suwon, South Korea); Fadel ADIB (Cambridge, Massachusetts) |
| ABSTRACT | A communication system may communicate by backscattered acoustic signals that propagate through a liquid or solid. In this system, one or more transmitters may transmit acoustic signals that travel to, and are reflected by, an acoustic backscatter node. The backscatter node may modulate the amplitude and/or phase of the reflected acoustic signals, by varying the acoustic reflectance of a piezoelectric transducer onboard the node. The modulated signals that reflect from the backscatter node may travel to a microphone and may be decoded. The backscatter node may include sensors, and the uplink signals may encode sensor readings. The backscatter node may harvest energy from the downlink acoustic signals, enabling the node and the sensors to be battery-free. Multiple backscatter nodes may communicate concurrently at different acoustic frequencies. To achieve this, each node may have a matching circuit with a different resonant frequency. |
| FILED | Monday, August 22, 2022 |
| APPL NO | 17/821245 |
| CURRENT CPC | Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 11/08 (20130101) Transmission H04B 11/00 (20130101) Original (OR) Class H04B 13/02 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 1/44 (20130101) H04R 17/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230009301 | Harshman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sean Harshman (Fairborn, Ohio); Mark Hawkins (Tipp City, Ohio) |
| ABSTRACT | A flow regulation device for volatile and semi-volatile sampling onto adsorbent media is provided. The flow regulation device includes a housing having an inlet, an outlet, a secondary inlet that is open to the ambient, a real time flow meter, a controller in electronic communication with the flow meter, and a three-way valve. Gas is drawn through the adsorbent media, into the inlet, and then to the outlet by a vacuum source joined to the outlet. The controller is configured to: (1) actuate the three-way valve to put the vacuum source in-line with the inlet; (2) continuously monitor the flow of gas through the inlet and calculate the time necessary to sample a pre-set volume of gas; and (3) after the pre-set volume of gas passes through the inlet, actuate the three-way valve to put the vacuum source in-line with the secondary inlet. |
| FILED | Tuesday, June 14, 2022 |
| APPL NO | 17/839524 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/24 (20130101) Original (OR) Class G01N 2001/248 (20130101) G01N 2001/2244 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230010032 | Griffin |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Brittany Consuegra Griffin (Huntsville, Alabama) |
| ABSTRACT | An acoustic-metamaterial acts as a sound reducing filter in that the level of sound that exits the structure is much less than the magnitude of sound that enters the structure. In forming the structure, modular stages of a given geometry are stacked upon one another to create a cell. Each stage of the cell is provided with a nozzle that is acoustically connected to the nozzles of other stages of the cell. The stages have chambers that are positioned radially or laterally outside of the respective nozzles, with the chambers of the cell being acoustically connected to one another. An amalgamation of cells are arranged in an adjacent formation, with chambers of the cells being acoustically connected to one another for purposes of protecting items, components and people from destructive levels of sound. |
| FILED | Thursday, July 07, 2022 |
| APPL NO | 17/859934 |
| CURRENT CPC | Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 11/162 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230010741 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Liping Wang (Chandler, Arizona); Rajagopalan Ramesh (Tempe, Arizona); Qing Ni (Hefei, China PRC) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Liping Wang (Chandler, Arizona); Rajagopalan Ramesh (Tempe, Arizona); Qing Ni (Hefei, China PRC) |
| ABSTRACT | A selective emitter for thermophotovoltaic energy conversion and method for fabricating the same is disclosed. The selective emitter includes a germanium wafer, and a reflective layer deposited on a first side of the germanium wafer. The reflective layer includes tungsten. The selective emitter also includes an anti-reflective layer deposited on a second side of the germanium wafer opposite the first side. The anti-reflective layer includes Si3N4. The method for fabricating a selective emitter for thermophotovoltaic energy conversion includes deposing a reflective layer on a first side of a germanium wafer, and deposing an anti-reflective layer on a second side of the germanium wafer, the first side being opposite the second side. The germanium wafer may be undoped. The reflective layer may be sputtered onto the germanium wafer. The anti-reflective layer may be deposited on the germanium wafer using plasma-enhanced chemical vapor deposition. |
| FILED | Thursday, July 07, 2022 |
| APPL NO | 17/859987 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/028 (20130101) H01L 31/056 (20141201) H01L 31/1808 (20130101) H01L 31/02168 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 10/30 (20141201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230011140 | Bo |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rui Bo (Rolla, Missouri) |
| ABSTRACT | A method for generating a model of an electric power network comprises receiving a description of an electric power network, the electric power network including a plurality of interconnected nodes; selecting a plurality of electric power network branches of focus from the description of the electric power network; generating a plurality of electric power network operating conditions of interest; updating the electric power network branches of focus to include data regarding critical operating conditions of interest; clustering nodes of the electric power network to form a plurality of super nodes; generating a reduced electric power network topology that includes the super nodes; generating a plurality of reduced electric power network electrical parameters; and outputting an electric power network model that includes the reduced electric power network topology and the reduced electric power network electrical parameters. |
| FILED | Friday, July 08, 2022 |
| APPL NO | 17/860423 |
| CURRENT CPC | Electric Digital Data Processing G06F 30/18 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230011295 | Griffin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as Represented by the Secretary of the Army (Washingon, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Secretary of the Army (Washingon, District of Columbia) |
| INVENTOR(S) | Brittany Consuegra Griffin (Huntsville, Alabama); Thomas J. DuPuy, V (Madison, Alabama); Ronald S. Legowik (Winchester, Tennessee); Gregory T. Jones (Meridianville, Alabama) |
| ABSTRACT | An acoustic metamaterial structure acts as a sound reducing filter in that the level of sound that exits the structure is much less than the magnitude of sound that enters the structure. In forming the structure, modular stages of a given geometry are stacked upon one another to create a cell. Each stage of the cell is provided with a nozzle that is acoustically connected to the nozzles of other stages of the cell. The stages have chambers that are positioned radially or laterally outside of the respective nozzles, with the chambers of the cell being acoustically connected to one another. An amalgamation of cells are arranged in an adjacent formation, with chambers of the cells being acoustically connected to one another for purposes of protecting items, components and people from destructive levels of sound. The geometry of the nozzles and chambers are designed for economical additive manufacture with acoustic infills. |
| FILED | Thursday, July 07, 2022 |
| APPL NO | 17/860009 |
| CURRENT CPC | Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 11/162 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230011770 | ROSI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (PITTSBURGH, Pennsylvania) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (PITTSBURGH, Pennsylvania) |
| INVENTOR(S) | Nathaniel L. ROSI (Pittsburgh, Pennsylvania); Tianyi LUO (Baltimore, Maryland); Prasenjit DAS (Pittsburgh, Pennsylvania) |
| ABSTRACT | The invention relates to luminescence-based compounds, compositions and methods for chemical sensing in solid state and solutions. More particularly, the invention includes “turn-on” lanthanide sensors that luminesce only in the presence of an organic compound (analyte) and are non-emissive in the absence of the organic compound (analyte). |
| FILED | Monday, December 14, 2020 |
| APPL NO | 17/781402 |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/182 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 31/22 (20130101) Original (OR) Class G01N 2021/6439 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230011824 | Chisum et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan Chisum (South Bend, Indiana); Nicolas Garcia (South Bend, Indiana) |
| ABSTRACT | An electromagnetic antenna includes a channel configured to serve as a waveguide for electromagnetic radiation, a first and second feed disposed next to each other inside the channel at a first end thereof, the first and second feed being configured to radiate electromagnetic waves into the channel, an aperture lens disposed inside the channel near a second end thereof opposite to the first end, the aperture lens being configured to output collimated beams, a first focal lens disposed inside the channel adjacent to an outlet of the first feed, the first focal lens being configured to squint a beam radiated from the first feed toward a center of the aperture lens, and a second focal lens disposed inside the channel adjacent to an outlet of the second feed, the second focal lens being configured to squint a beam radiated from the second feed toward the center of the aperture lens. |
| FILED | Friday, April 15, 2022 |
| APPL NO | 17/721898 |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 19/062 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230011913 | Henriksen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri); the Trustees of Boston College (Chestnut Hill, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Erik Henriksen (St. Louis, Missouri); Jesse Balgley (St. Louis, Missouri); Kenneth S. Burch (Newton, Massachusetts); Yiping Wang (Brighton, Massachusetts) |
| ABSTRACT | The present disclosure is directed to controlling charge transfer in 2D materials. A charge-transfer controlled 2D device comprises a 2D active conducting material, a 2D charge transfer source material, and at least one overlapping portion wherein the 2D active conducting material overlaps the 2D charge transfer source material including at least one edge of the 2D charge transfer source material. |
| FILED | Tuesday, July 12, 2022 |
| APPL NO | 17/811934 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/205 (20130101) H01L 29/2003 (20130101) H01L 29/7786 (20130101) Original (OR) Class H01L 29/41725 (20130101) H01L 29/66431 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230012266 | Zakar |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Combat Capabiities Development Command, Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eugene S. Zakar (Bethesda, Maryland) |
| ABSTRACT | A maskless, patterned graphene film is produced through use of a tunable metal as a catalyst for graphene growth. The metal layer contains precisely defined textures that control the formation of the graphene film. Specifically, graphene growth can be controlled from F-LG (few layer graphene) down to 2-LG (2-layer graphene) and 1-LG (1-layer graphene). More than one texture can be created to form maskless patterns of graphene. Once the graphene layer(s) are grown, the film can be released from the metal and applied to any form and shape of rigid or flexible substrate for a variety of different applications where graphene cannot be normally grown directly. |
| FILED | Monday, September 19, 2022 |
| APPL NO | 17/947514 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/186 (20170801) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02527 (20130101) H01L 29/1606 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230012390 | NEMANICK et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Eric Joseph NEMANICK (Santa Monica, California); Ann L. CHERVENAK (Los Angeles, California); Joseph Z. FUERST (Beavercreek, Ohio); Andrew BRETHORST (Hawthorne, California); Michael R. HALE (West Hollywood, California); Kevin MACDOUGALL (Torrance, California); Justin STOCKER (Sherman Oaks, California) |
| ABSTRACT | A self-regulating battery may generate a basis state for one or more modules using one or more system inputs. The system inputs comprise current, voltage, and battery degradation. The battery generates a family of weighted forecasts for future bus demands using usage and performance based weights. The battery generates one or more plans to support demand from the battery using the weighted forecasts. The battery scores the one or more plans based on efficiency of power extraction from the battery, and combines the scored one or more plans with an updated SoH value based on induced degradation from a usage plan. The battery generates the combined scored for each of the one or more plans, and transmits one of the combined scored to the battery management unit for execution. |
| FILED | Wednesday, July 07, 2021 |
| APPL NO | 17/369895 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/48 (20130101) Original (OR) Class H01M 10/4257 (20130101) H01M 2010/4271 (20130101) H01M 2010/4278 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20230009628 | HUSAIN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | JLabs, Co. (McLean, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | JAMIL HUSAIN (ARLINGTON, Virginia); JEFFREY DAWSON (ARLINGTON, Virginia); DAVID WHITE (ARLINGTON, Virginia) |
| ABSTRACT | Described herein are rapid breath testing devices, systems and methods. The device may include a mouthpiece operable to receive air flow from a breath; and a cassette comprising a biosensor and a cassette conduit, the cassette removably connected to the mouthpiece such that at least a sample of the air flow passes through the cassette conduit and over the biosensor. The biosensor may include a plurality of graphene-based sensors and may be operable to detect at least one volatile organic compound in the air flow sample. |
| FILED | Thursday, September 01, 2022 |
| APPL NO | 17/901048 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/05 (20130101) A61B 5/095 (20130101) A61B 5/097 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/22 (20130101) G01N 33/497 (20130101) G01N 33/5302 (20130101) Original (OR) Class G01N 33/54346 (20130101) G01N 33/54388 (20210801) G01N 2033/4975 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230010473 | Roach et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho); Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert A. Roach (Idaho Falls, Idaho); Andrea M. Jokisaari (Idaho Falls, Idaho); Michael D. McMurtrey (Idaho Falls, Idaho); Geoffrey L. Beausoleil (Idaho Falls, Idaho); Carolyn L. Seepersad (Austin, Texas) |
| ABSTRACT | A test capsule for measuring at least one property of a material exposed to nuclear radiation comprises a lattice structure configured to exhibit a change in at least one property responsive to exposure to nuclear radiation. The lattice structure comprises a first strut and a second strut connected to the first strut at a node. Related test capsules and methods are also described. |
| FILED | Friday, June 24, 2022 |
| APPL NO | 17/808944 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230010722 | Burkart et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael D. Burkart (La Jolla, California); Thien An Phung Hai (La Jolla, California) |
| ABSTRACT | Disclosed herein, inter alia, are fatty acid and polymer compositions and methods of making the same. |
| FILED | Friday, October 16, 2020 |
| APPL NO | 17/765347 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 51/34 (20130101) C07C 67/08 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/4288 (20130101) Original (OR) Class C08G 63/16 (20130101) C08G 63/78 (20130101) C08G 2110/0008 (20210101) C08G 2110/0083 (20210101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/125 (20130101) Fatty Acids From Fats, Oils or Waxes; Candles; Fats, Oils or Fatty Acids by Chemical Modification of Fats, Oils, or Fatty Acids Obtained Therefrom C11C 1/007 (20130101) C11C 1/08 (20130101) C11C 1/025 (20130101) Detergent Compositions; Use of Single Substances as Detergents; Soap or Soap-making; Resin Soaps; Recovery of Glycerol C11D 9/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230010771 | Coridan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert Henry Coridan (Fayetteville, Arkansas); Zebulon George Schichtl (Conway, Arkansas); Hamed Mehrabi (Fayetteville, Arkansas) |
| ABSTRACT | One aspect of the invention provides a photoelectrochemical device including at least one electrochemical cell comprising an anode electrode and a cathode electrode; and a photovoltaic module integrated with the at least one electrochemical cell and adapted for converting energy of photons to electrical energy for driving the at least one electrochemical cell to facilitate redox reactions therein. |
| FILED | Thursday, July 07, 2022 |
| APPL NO | 17/859109 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/02 (20130101) C25B 11/081 (20210101) C25B 11/087 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230010888 | Kumar |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sortera Alloys, Inc. (Fort Worth, Texas) |
| ASSIGNEE(S) | Sortera Alloys, Inc. (Fort Worth, Texas) |
| INVENTOR(S) | Nalin Kumar (Fort Worth, Texas) |
| ABSTRACT | Aluminum scrap pieces are sorted into selected alloys and then fed into a vacuum smelting furnace to melt. The aluminum scrap pieces may be sorted into various cast aluminum alloy series, wrought aluminum alloy series, or extrusion aluminum alloy series. The sorting may be performed using x-ray fluorescence, artificial intelligence, or laser induced breakdown spectroscopy. |
| FILED | Wednesday, June 29, 2022 |
| APPL NO | 17/852969 |
| CURRENT CPC | Production and Refining of Metals; Pretreatment of Raw Materials C22B 21/0092 (20130101) Alloys C22C 1/026 (20130101) C22C 21/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230011108 | Rushford et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Rushford (Livermore, California); Adam Conway (Livermore, California); Lars F. Voss (Livermore, California); Joseph D. Schneider (Livermore, California); Tammy Chang (Livermore, California); Caitlin Anne Chapin (Livermore, California); John Berns Lancaster (Livermore, California); Steve Hawkins (Livermore, California); Victor Valeryevich Khitrov (Livermore, California) |
| ABSTRACT | Methods and devices for illuminating a photoconductive switch consisting of an optically actuated photoconductive material situated between two electrodes are described. Light from a light source is coupled to an optical fiber, which is attached to a frustum, the other side of which is proximate to the photoconductive switch. Light from the optical fiber enters the frustum, spreads out, and enters the photoconductive switch via the top-side electrode. Some of the light is absorbed, while the remaining light reflects off the bottom-side electrode, travels back through the photoconductive switch, and any unabsorbed light reenters the frustum. The geometry of the frustum is configured such that most of the light reflects back into the switch itself with only a negligible fraction escaping from the optical fiber, which advantageously results in near total utilization of the light. |
| FILED | Friday, July 09, 2021 |
| APPL NO | 17/372366 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/262 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230011193 | Baliga |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bantval Jayant Baliga (Raleigh, North Carolina) |
| ABSTRACT | A power device includes a semiconductor substrate having first and second current carrying terminals on respective first and second opposing surfaces thereof. A silicided polysilicon temperature sensor and silicided polysilicon gate electrode are provided on the first surface. A source region of first conductivity type and a shielding region of second conductivity type are provided in the semiconductor substrate. The shielding region forms a P-N rectifying junction with the source region, and extends between the silicided polysilicon temperature sensor and the second current carrying terminal. A field oxide insulating region is provided, which extends between the shielding region and the silicided polysilicon temperature sensor. |
| FILED | Tuesday, August 02, 2022 |
| APPL NO | 17/816993 |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 7/186 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/0615 (20130101) H01L 29/1608 (20130101) H01L 29/4933 (20130101) H01L 29/7395 (20130101) H01L 29/7803 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230011274 | Dai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Apple Inc. (Cupertino, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hongli Dai (Los Altos, California); Libo Hu (Mountain View, California); Paul M. Bayley (Santa Clara, California); Zhengcheng Zhang (Naperville, Illinois); Qian Liu (Darien, Illinois); Khalil Amine (Oak Brook, Illinois); Mingfu He (Palos Park, Illinois) |
| ABSTRACT | This disclosure relates generally to battery cells, and more particularly, electrolyte additives for use in lithium ion battery cells. |
| FILED | Wednesday, June 08, 2022 |
| APPL NO | 17/835758 |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/02 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0567 (20130101) Original (OR) Class H01M 10/0568 (20130101) H01M 10/0569 (20130101) H01M 2300/0042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230011618 | Duquette et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LITTORAL POWER SYSTEMS, INC. (New Bedford, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David J. Duquette (Fairhaven, Massachusetts); Katherine Leighton (Media, Pennsylvania); Luke Graham (Eagle River, Alaska); Vince Bryan (Seattle, Washington) |
| ABSTRACT | Zero-ascend omnispecies (ZAO) attraction system includes a fish passage attraction module that can be deployed in a fishway where water flows downstream. The fish passage attraction module includes a body having a first end and an opposite second end, first adaptor adjacent the first end and second adaptor adjacent the second end. The adaptors are configured to alter water flow fields downstream of the module so as to attract fish to an entrance thereof. |
| FILED | Friday, July 08, 2022 |
| APPL NO | 17/860740 |
| CURRENT CPC | Hydraulic Engineering E02B 8/085 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230011863 | CHERUKURI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NVIDIA CORPORATION (Santa Clara, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | NAVEEN CHERUKURI (San Jose, California); SAURABH HUKERIKAR (Santa Clara, California); PAUL RACUNAS (Landaff, New Hampshire); NIRMAL RAJ SAXENA (LOS ALTOS HILLS, California); DAVID CHARLES PATRICK (MADISON, Alabama); YIYANG FENG (San Jose, California); ABHIJEET GHADGE (San Jose, California); STEVEN JAMES HEINRICH (Madison, Alabama); ADAM HENDRICKSON (San Jose, California); GENTARO HIROTA (Sunnyvale, California); PRAVEEN JOGINIPALLY (San Jose, California); VAISHALI KULKARNI (Sunnyvale, California); PETER C. MILLS (San Jose, California); SANDEEP NAVADA (San Jose, California); MANAN PATEL (San Jose, California); LIANG YIN (San Jose, California) |
| ABSTRACT | Various embodiments include a parallel processing computer system that detects memory errors as a memory client loads data from memory and disables the memory client from storing data to memory, thereby reducing the likelihood that the memory error propagates to other memory clients. The memory client initiates a stall sequence, while other memory clients continue to execute instructions and the memory continues to service memory load and store operations. When a memory error is detected, a specific bit pattern is stored in conjunction with the data associated with the memory error. When the data is copied from one memory to another memory, the specific bit pattern is also copied, in order to identify the data as having a memory error. |
| FILED | Monday, July 12, 2021 |
| APPL NO | 17/373678 |
| CURRENT CPC | Electric Digital Data Processing G06F 11/0772 (20130101) G06F 11/0793 (20130101) G06F 11/1016 (20130101) Original (OR) Class G06F 11/1407 (20130101) G06F 12/1018 (20130101) G06F 12/1027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230012000 | Heher et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Transportation IP Holdings, LLC (Norwalk, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brett Heher (Pittsburgh, Pennsylvania); Kevin Paul Bailey (Mercer, Pennsylvania); Manuel Licon Flores (Erie, Pennsylvania); Adam Edgar Klingbeil (Ballston Lake, New York); John Patrick Dowell (Grove City, Pennsylvania) |
| ABSTRACT | An insert device includes a first coupling body inserted into an engine cylinder head. The first coupling body extends around a center axis to define a first interior volume of the first coupling body that is shaped to receive a distal tip of a fuel injector. The insert device includes a second mixing body coupled with the first coupling body and extending around the center axis. The second mixing body includes conduits that receive fuel from the fuel injector and air from a combustion chamber, combine the fuel with the air, and direct the fuel-air mixture into the combustion chamber. The first coupling body has a first end surface positioned to face the cylinder head and the first coupling body is tapered such that an outer diameter of the first coupling body is larger toward the first end surface than toward the second mixing body. |
| FILED | Wednesday, July 07, 2021 |
| APPL NO | 17/369561 |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/0446 (20130101) B01F 5/0426 (20130101) B01F 2215/0086 (20130101) Spraying Apparatus; Atomising Apparatus; Nozzles B05B 7/12 (20130101) Supplying Combustion Engines in General With Combustible Mixtures or Constituents Thereof F02M 61/14 (20130101) Original (OR) Class F02M 61/16 (20130101) F02M 2200/85 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230012465 | Han et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bong-Gyoon Han (Castro Valley, California); Robert M. Glaeser (Berkeley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Bong-Gyoon Han (Castro Valley, California); Robert M. Glaeser (Berkeley, California) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus related to graphene. In one aspect, a method includes submerging a frame support in an etching solution that is contained in a container. A growth substrate, a graphene sheet disposed on the growth substrate, and a primary support disposed on the graphene sheet is placed on a surface of the etching solution. The growth substrate is dissolved in the etching solution to leave the graphene sheet and the primary support floating on a surface of the etching solution. The etching solution in the container is replaced with a washing solution. The washing solution is removed from the container so that the graphene sheet becomes disposed on the frame support. |
| FILED | Thursday, August 06, 2020 |
| APPL NO | 16/987173 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/194 (20170801) C01B 2204/02 (20130101) C01B 2204/04 (20130101) Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 1/08 (20130101) C23F 1/18 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 37/20 (20130101) H01J 2235/183 (20130101) H01J 2237/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20230008026 | Gu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yuyang Gu (Durham, North Carolina); Tony Jun Huang (Durham, North Carolina) |
| ABSTRACT | The present disclosure provides for acoustofluidic centrifuge systems that can enrich and separate nanoparticles disposed in a fluid, such as liquid droplets, in a fast and efficient manner. Exemplary systems include a sound wave generator, such as a pair of slanted interdigitated transducers, and a containment boundary, such as a PDMS ring. The sound wave generator can produce surface acoustic waves that are capable of driving droplets to spin in a manner that can separate different sized particles into groups. In some embodiments, the acoustofluidic centrifuge system can include a plurality of containment boundaries in fluid communication with each other, allowing particles to separate between the containment boundaries. Methods of operating such systems, including methods of isolating different exosome subpopulations, are also disclosed. |
| FILED | Tuesday, April 12, 2022 |
| APPL NO | 17/719307 |
| CURRENT CPC | Separation B01D 21/283 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) Original (OR) Class B01L 2200/0652 (20130101) B01L 2400/0436 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4077 (20130101) G01N 21/6428 (20130101) G01N 2001/4094 (20130101) G01N 2021/6439 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230008590 | Hersam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark C. Hersam (Wilmette, Illinois); Qiucheng Li (Evanston, Illinois); Xiaolong Liu (Ithaca, New York); Eden B Aklile (Evanston, Illinois) |
| ABSTRACT | This invention in one aspect relates to a method of synthesizing a self-assembled mixed-dimensional heterostructure including 2D metallic borophene and 1D semiconducting armchair-oriented graphene nanoribbons (aGNRs). The method includes depositing boron on a substrate to grow borophene thereon at a substrate temperature in an ultrahigh vacuum (UHV) chamber; sequentially depositing 4,4″-dibromo-p-terphenyl on the borophene grown substrate at room temperature in the UHV chamber to form a composite structure; and controlling multi-step on-surface coupling reactions of the composite structure to self-assemble a borophene/graphene nanoribbon mixed-dimensional heterostructure. The borophene/aGNR lateral heterointerfaces are structurally and electronically abrupt, thus demonstrating atomically well-defined metal-semiconductor heterojunctions. |
| FILED | Tuesday, April 19, 2022 |
| APPL NO | 17/723595 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/184 (20170801) Original (OR) Class C01B 35/023 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02425 (20130101) H01L 21/02491 (20130101) H01L 21/02499 (20130101) H01L 21/02516 (20130101) H01L 21/02527 (20130101) H01L 21/02603 (20130101) H01L 21/02617 (20130101) H01L 21/28506 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230009830 | Zheng |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | University of Connecticut (Farmington, Connecticut) |
| INVENTOR(S) | Guoan Zheng (Vernon, Connecticut) |
| ABSTRACT | An imaging system includes a sample mount for holding a sample to be imaged, a light source configured to emit a light beam to be incident on the sample, a translation mechanism coupled to the sample mount and configured to scan the sample to a plurality of sample positions in a plane substantially perpendicular to an optical axis of the imaging system, a mask positioned downstream from the sample along the optical axis, and an image sensor positioned downstream from the mask along the optical axis. The image sensor is configured to acquire a plurality of images as the sample is translated to the plurality of sample positions. Each respective image corresponds to a respective sample position. The imaging system further includes a processor configured to process the plurality of images to recover a complex profile of the sample based on positional shifts extracted from the plurality of images. |
| FILED | Friday, September 16, 2022 |
| APPL NO | 17/946833 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/2806 (20130101) G01N 15/10 (20130101) G01N 2015/1493 (20130101) Optical Elements, Systems, or Apparatus G02B 21/36 (20130101) G02B 21/367 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230010741 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Liping Wang (Chandler, Arizona); Rajagopalan Ramesh (Tempe, Arizona); Qing Ni (Hefei, China PRC) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Liping Wang (Chandler, Arizona); Rajagopalan Ramesh (Tempe, Arizona); Qing Ni (Hefei, China PRC) |
| ABSTRACT | A selective emitter for thermophotovoltaic energy conversion and method for fabricating the same is disclosed. The selective emitter includes a germanium wafer, and a reflective layer deposited on a first side of the germanium wafer. The reflective layer includes tungsten. The selective emitter also includes an anti-reflective layer deposited on a second side of the germanium wafer opposite the first side. The anti-reflective layer includes Si3N4. The method for fabricating a selective emitter for thermophotovoltaic energy conversion includes deposing a reflective layer on a first side of a germanium wafer, and deposing an anti-reflective layer on a second side of the germanium wafer, the first side being opposite the second side. The germanium wafer may be undoped. The reflective layer may be sputtered onto the germanium wafer. The anti-reflective layer may be deposited on the germanium wafer using plasma-enhanced chemical vapor deposition. |
| FILED | Thursday, July 07, 2022 |
| APPL NO | 17/859987 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/028 (20130101) H01L 31/056 (20141201) H01L 31/1808 (20130101) H01L 31/02168 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 10/30 (20141201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230011622 | Tilly et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan L. Tilly (Windham, New Hampshire); Dori Woods (Londonderry, New Hampshire) |
| ABSTRACT | Disclosed are methods for increasing the fertilization rate of an oocyte in a granulosa cell-oocyte complex, and/or the success rate of in-vitro fertilization by using mitochondrial therapies. Also disclosed are methods of identifying compounds for fertility treatment. |
| FILED | Monday, February 22, 2021 |
| APPL NO | 17/801406 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0609 (20130101) C12N 15/873 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230011913 | Henriksen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Washington University (St. Louis, Missouri); the Trustees of Boston College (Chestnut Hill, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Erik Henriksen (St. Louis, Missouri); Jesse Balgley (St. Louis, Missouri); Kenneth S. Burch (Newton, Massachusetts); Yiping Wang (Brighton, Massachusetts) |
| ABSTRACT | The present disclosure is directed to controlling charge transfer in 2D materials. A charge-transfer controlled 2D device comprises a 2D active conducting material, a 2D charge transfer source material, and at least one overlapping portion wherein the 2D active conducting material overlaps the 2D charge transfer source material including at least one edge of the 2D charge transfer source material. |
| FILED | Tuesday, July 12, 2022 |
| APPL NO | 17/811934 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/205 (20130101) H01L 29/2003 (20130101) H01L 29/7786 (20130101) Original (OR) Class H01L 29/41725 (20130101) H01L 29/66431 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230012063 | Yu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York); University of Notre Dame (Notre Dame, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Wenhao Yu (Mishawaka, Indiana); LINGFEI WU (Elmsford, New York); Yu Deng (Yorktown Heights, New York); Qingkai Zeng (Granger, Indiana); Ruchi Mahindru (Elmsford, New York); Sinem Guven Kaya (New York, New York); Meng Jiang (Granger, Indiana) |
| ABSTRACT | An approach for a non-factoid question answering framework across tasks and domains may be provided. The approach may include training a multi-task joint learning model in a general domain. The approach may also include initializing the multi-task joint learning model in a specific target domain. The approach may include tuning the joint learning model in the target domain. The approach may include determining which task of the multiple tasks is more difficult for the multi-task joint learning model to learn. The approach may also include dynamically adjusting the weights of the multi-task joint learning model, allowing the model to concentrate on learning the more difficult learning task. |
| FILED | Wednesday, July 07, 2021 |
| APPL NO | 17/369040 |
| CURRENT CPC | Electric Digital Data Processing G06F 16/90332 (20190101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00483 (20130101) G06K 9/628 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 20230008019 | TAO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yang TAO (Potomac, Maryland); Anjana HEVAGANINGE (Rockville, Maryland); Chiao-Yi WANG (College Park, Maryland); Dongyi WANG (Fayetteville, Arkansas); Mohamed Amr ALI (College Park, Maryland) |
| ABSTRACT | A non-contact system for the sensing of pH includes a hyperspectral imaging device configured to capture a hyperspectral image of a fluid, a flow cell configured to enable the capturing of a hyperspectral image of a fluid, a process, and a memory. The memory includes instructions stored thereon, which, when executed by the processor, cause the system to generate a hyperspectral image of the fluid in the flow cell, generate several spectral signals based on the hyperspectral image, provide the spectral signal as an input to a machine learning network, and predict by the machine learning network a pH of a fluid. |
| FILED | Friday, July 08, 2022 |
| APPL NO | 17/860428 |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/108 (20130101) G01J 3/2823 (20130101) G01J 2003/2843 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/3577 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230010416 | TAO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yang TAO (Potomac, Maryland); Chiao-Yi WANG (College Park, Maryland); Anjana HEVAGANINGE (Rockville, Maryland); Dongyi WANG (Fayetteville, Arkansas); Mohamed Amr ALI (College Park, Maryland) |
| ABSTRACT | A non-contact system for the sensing the concentration of a compound includes a hyperspectral imaging device configured to capture a hyperspectral image of a fluid, a flow cell configured to enable the capturing of a hyperspectral image of a fluid, a process, and a memory. The memory includes instructions stored thereon which, when executed by the processor, cause the system to generate a hyperspectral image of the fluid in the flow cell, generate several spectral signals based on the hyperspectral image, provide the spectral signal as an input to a machine learning network, and predict by the machine learning network the concentration of a compound in a fluid. |
| FILED | Friday, July 08, 2022 |
| APPL NO | 17/860412 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/359 (20130101) G01N 21/3577 (20130101) Original (OR) Class G01N 2201/126 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20230011248 | HILLYER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | MATTHEW B HILLYER (NEW ORLEANS, Louisiana); SUNGHYUN NAM (METAIRIE, Louisiana); BRIAN D CONDON (METAIRIE, Louisiana) |
| ABSTRACT | The invention relates to treated cellulosic fibers comprising internally dispersed cuprous oxide (Cu2O) nanoparticles, methods of preparing such treated cellulosic fibers, and uses of such treated cellulosic fibers. |
| FILED | Friday, July 09, 2021 |
| APPL NO | 17/371906 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/34 (20130101) A01N 59/20 (20130101) Original (OR) Class Preserving, e.g by Canning, Meat, Fish, Eggs, Fruit, Vegetables, Edible Seeds; Chemical Ripening of Fruit or Vegetables; the Preserved, Ripened, or Canned Products A23B 4/20 (20130101) A23B 4/24 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/232 (20130101) A61L 9/012 (20130101) A61L 2101/26 (20200801) A61L 2202/26 (20130101) Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 65/42 (20130101) B65D 81/28 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 11/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20230008245 | Burkhardt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brian Burkhardt (Richmond, Virginia); Seth Hills (Richmond, Virginia); John Miller (Richmond, Virginia); Melissa Oliver (Richmond, Virginia) |
| ABSTRACT | An adaptive holder is used to provide those lacking fine hand motor control skills and limited arm and shoulder range of motion with the ability to conveniently extend and orient utensils such as forks and spoons. Used with a universal adapter cuff, the holder includes a slotted head which receives the utensil handle. A gripping portion, attached to the head, is received by the cuff. The utensil may be angularly oriented relative to the head and is secured thereto by a frictional interference fit. |
| FILED | Friday, July 08, 2022 |
| APPL NO | 17/860524 |
| CURRENT CPC | Household or Table Equipment A47G 21/02 (20130101) Handles for Hand Implements B25G 1/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20230009761 | Bryant |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (WASHINGTON, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert G. Bryant (Lightfoot, Virginia) |
| ABSTRACT | Systems, methods, and devices of the various embodiments may provide Automated Tape (or Tow) Placement (ATP) systems including machine-based parts that support prepreg tape laying processes to build composite parts. Various embodiments may be applied to materials that may be consolidated during fabrication and/or may be used to fabricate parts that may require post processing steps. |
| FILED | Wednesday, July 07, 2021 |
| APPL NO | 17/369109 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 70/388 (20130101) Original (OR) Class B29C 70/545 (20130101) B29C 2793/0027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20230009842 | Boehme et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PowerTech Water Inc. (Lexington, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lindsay Boehme (Iowa City, Iowa); Cameron Lippert (Lexington, Kentucky); James Landon (Lexington, Kentucky); Alan Rassoolkhani (Lexington, Kentucky); Jeffrey Rentschler (Lexington, Kentucky) |
| ABSTRACT | The present invention is directed to an electrochemical device for at least partially removing or reducing a target ionic species from an aqueous solution using faradaic immobilization, the electrochemical device including at least one first electrode and at least one second electrode with different void fraction and surface area properties, due to differences in void fraction (also referred to as void ratio) of the at least one first and the at least one second electrode, water flows through an electrode with a high porosity, while the aqueous solution does not flow through an electrode with a low porosity. The asymmetry of the electrodes provides a desired voltage distribution across the device, which equates to a different voltage at each electrode, to control the speciation of the target ionic species at the anode and the cathode. |
| FILED | Wednesday, July 07, 2021 |
| APPL NO | 17/369346 |
| CURRENT CPC | Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor C25C 1/10 (20130101) Original (OR) Class C25C 7/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 20230009041 | Pantaleo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents, a body corporate of the State of Arizona acting for and on behalf of (Phoenix, Arizona); Consejo Superior De Investigaciones Cientificas (Madrid, Spain); IPPOX Foundation (Lausanne, Switzerland) |
| ASSIGNEE(S) | Arizona Board of Regents, a body corporate of the State of Arizona acting for and on behalf of (Phoenix, Arizona); Consejo Superior De Investigaciones Cientificas (Madrid, Spain); IPPOX Foundation (Lausanne, Switzerland) |
| INVENTOR(S) | Giuseppe Pantaleo (Lausanne, Switzerland); Thierry Calandra (Lausanne, Switzerland); Alexandre Harari (Lausanne, Switzerland); Thierry Roger (Lausanne, Switzerland); Mariano Esteban (Madrid, Spain); Bertram Jacobs (Phoenix, Arizona); Karen Kibler (Phoenix, Arizona); Cornelius Melief (Leiden, Netherlands); Rafick-Pierre Sekaly (Montreal, Canada); Elias Haddad (Montreal, Canada); James Tartaglia (Toronto, Canada) |
| ABSTRACT | The disclosure relates to recombinant vectors and methods for using the same. In certain embodiments, the recombinant vectors are immunogenic. |
| FILED | Thursday, April 28, 2022 |
| APPL NO | 17/732141 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/275 (20130101) A61K 39/295 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
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APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-applications-20230112.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page