FedInvent™ Patent Applications
Application Details for Thursday, January 19, 2023
This page was updated on Friday, January 20, 2023 at 12:32 PM GMT
Department of Health and Human Services (HHS)
| US 20230012702 | Huang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xuefei Huang (Okemos, Michigan); Jicheng Zhang (East Lansing, Michigan) |
| ABSTRACT | The present disclosure relates to disaccharides with defined sulfation patterns, and oligosaccharide mimetics comprising the disaccharides as repeating units linked in a head to tail fashion. The present disclosure further relates to methods of making the same, and to methods of using the same to mediate cell proliferation, cell differentiation, amyloid plaque formation, anti-coagulation, and neuronal growth. |
| FILED | Monday, September 21, 2020 |
| APPL NO | 17/761857 |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/00 (20130101) C07H 15/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230013145 | McCown et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thomas McCown (Carrboro, North Carolina); Sara Powell (Chapel Hill, North Carolina); Richard Jude Samulski (Hillsborough, North Carolina) |
| ABSTRACT | Disclosed herein are methods and compositions for gene therapy, in particular, methods and compositions related to alterations in a capsid protein sequence for altering permissiveness of a promoter within a cell when the promoter and the capsid protein are present within the cell and the capsid protein and the promoter are in the context of a recombinant adeno-associated virus (AAV) particle. |
| FILED | Wednesday, February 17, 2021 |
| APPL NO | 17/904433 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0025 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0618 (20130101) C12N 15/86 (20130101) C12N 2750/14122 (20130101) C12N 2750/14142 (20130101) C12N 2750/14145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230013313 | Park et al. |
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| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ki Yun Park (St. Louis, Missouri); Abraham Snyder (St. Louis, Missouri); Eric Leuthardt (St. Louis, Missouri) |
| ABSTRACT | A method for mapping brain function of a subject includes generating a lesion mask using a search light algorithm based on a plurality of anatomical images of the subject. The plurality of anatomical images are registered with atlas images by nonlinear atlas registration using the generated lesion mask to generate a warping map. A plurality of functional images of the subject are resampled using the warping map to generate a functional map, functional connectivity is computed using the functional map and a multi-layer perceptron. |
| FILED | Friday, September 09, 2022 |
| APPL NO | 17/930753 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 5/0263 (20130101) Image Data Processing or Generation, in General G06T 3/0093 (20130101) G06T 7/0014 (20130101) Original (OR) Class G06T 7/30 (20170101) G06T 2207/10088 (20130101) G06T 2207/30016 (20130101) G06T 2207/30096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230013752 | Leon et al. |
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| FUNDED BY |
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| APPLICANT(S) | Provention Bio, Inc. (Red Bank, New Jersey) |
| ASSIGNEE(S) | Provention Bio, Inc. (Red Bank, New Jersey) |
| INVENTOR(S) | Francisco Leon (Bethesda, Maryland); Kevan C. Herold (Norwalk, Connecticut); Jay S. Skyler (Key Biscayne, Florida) |
| ABSTRACT | Provided herein, in one aspect, is a method of preventing or delaying the onset of clinical type 1 diabetes (T1D), comprising: providing a non-diabetic subject who is at risk for T1D; determining that the non-diabetic subject (1) is substantially free of antibodies against zinc transporter 8 (ZnT8), (2) is HLA-DR4+, and/or (3) is not HLA-DR3+; and administering a prophylactically effective amount of an anti-CD3 antibody to the non-diabetic subject. |
| FILED | Friday, September 02, 2022 |
| APPL NO | 17/929573 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0053 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) Peptides C07K 16/2809 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230014028 | Muir et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Peter Muir (Madison, Wisconsin); Susannah Sample (Madison, Wisconsin); John Svaren (Madison, Wisconsin) |
| ABSTRACT | Methods for diagnosing propensity to exhibit acquired peripheral neuropathy in dogs are described. The methods and kits test dogs for presence of a disease-associated genomic variant. Presence of the genomic variant indicates an increased likelihood of the dog developing an acquired peripheral neuropathy. This information can be used to guide preemptive clinical treatment of the animal for peripheral neuropathy and to choose dogs for selective breeding programs. |
| FILED | Friday, September 16, 2022 |
| APPL NO | 17/946613 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230014056 | Jiang et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Shaoyi Jiang (Seattle, Washington); Xiaojie Lin (Seattle, Washington); Jonathan Himmelfarb (Seattle, Washington); Buddy D. Ratner (Seattle, Washington) |
| ABSTRACT | Zwitterionic carboxybetaine copolymers and their use in coatings to impart non-fouling and functionality to surfaces, particularly surfaces of blood-contacting medical devices. |
| FILED | Monday, September 12, 2022 |
| APPL NO | 17/931474 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 29/06 (20130101) A61L 29/041 (20130101) A61L 29/085 (20130101) A61L 29/141 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/28 (20130101) C08J 2333/26 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 133/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230014109 | Lindsley et al. |
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| FUNDED BY |
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| APPLICANT(S) | Craig W. Lindsley (Brentwood, Tennessee); P. Jeffrey Conn (Nashville, Tennessee); Darren W. Engers (Brentwood, Tennessee); Sean Bollinger (Murfreesboro, Tennessee); James C. Tarr (Franklin, Tennessee); Paul Spearing (Chapel Hill, Tennessee); Julie L. Engers (Brentwood, Tennessee); Madeline Long (Nashville, Tennessee); Thomas M. Bridges (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Craig W. Lindsley (Brentwood, Tennessee); P. Jeffrey Conn (Nashville, Tennessee); Darren W. Engers (Brentwood, Tennessee); Sean Bollinger (Murfreesboro, Tennessee); James C. Tarr (Franklin, Tennessee); Paul Spearing (Chapel Hill, Tennessee); Julie L. Engers (Brentwood, Tennessee); Madeline Long (Nashville, Tennessee); Thomas M. Bridges (Nashville, Tennessee) |
| ABSTRACT | Disclosed herein are tricyclic compounds, including pyrimido[4′,5′:4,5]thieno[2,3-c]pyridazine-8-amine, pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidine-4-amine, pyrazino[2′,3′:4,5]thieno[3,2-d]pyrimidin-4-amine, pyrido[3′,2′:4,5]furo[3,2-d]pyrimidin-4-amine, and pyrimido[4′,5′:4,5]furo[2,3-c]pyridazin-8-amine compounds, which may be useful as positive allosteric modulators of the muscarinic acetylcholine receptor M4 (mAChR M4). Also disclosed herein are methods of making the compounds, pharmaceutical compositions comprising the compounds, and methods of treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction using the compounds and compositions. |
| FILED | Wednesday, September 08, 2021 |
| APPL NO | 17/469178 |
| CURRENT CPC | Heterocyclic Compounds C07D 493/14 (20130101) C07D 495/14 (20130101) Original (OR) Class C07D 519/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230014151 | POROTTO et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York); Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matteo POROTTO (New York, New York); Anne MOSCONA (New York, New York); Christopher ALABI (Ithaca, New York) |
| ABSTRACT | Described herein are peptides, compositions, and method of treating measles or HIV infection with antiviral peptide conjugates comprising a fusion inhibitory peptide (FIP) conjugated to a C-terminal heptad repeat (HRC) peptide. Also described herein are soluble stabilized measles F proteins, compositions, and method of preventing measles infection with the stabilized F protein, which can be administered alone, or in combination with the antiviral peptide conjugates described herein. |
| FILED | Friday, September 04, 2020 |
| APPL NO | 17/640327 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/21 (20130101) Original (OR) Class A61K 39/165 (20130101) A61K 2039/6075 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) A61P 31/18 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230014352 | ZEKI et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Amir A. ZEKI (Davis, California); Chandra C. GHOSH (Boston, Massachusetts); Ramaswamy KRISHNAN (Boston, Massachusetts) |
| ABSTRACT | present disclosure relates to methods for relaxing airway smooth muscle tissue, alleviating or preventing bronchospasm, and treating lung diseases by administering an HMG-CoA reductase inhibitor (statin) directly to lung tissue by inhalation. The disclosure also relates to formulations and compositions useful for the practice of methods of the disclosure. |
| FILED | Friday, March 27, 2020 |
| APPL NO | 17/598568 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0078 (20130101) A61K 31/24 (20130101) A61K 31/40 (20130101) A61K 31/44 (20130101) A61K 31/46 (20130101) A61K 31/47 (20130101) Original (OR) Class A61K 31/137 (20130101) A61K 31/366 (20130101) A61K 31/381 (20130101) A61K 31/439 (20130101) A61K 31/505 (20130101) A61K 31/522 (20130101) A61K 31/573 (20130101) A61K 31/4025 (20130101) A61K 31/4545 (20130101) A61K 31/4741 (20130101) A61K 31/5386 (20130101) A61K 39/3955 (20130101) A61K 39/39566 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/08 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230014430 | Millman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Jeffrey Millman (St. Louis, Missouri); Daniel Veronese Paniagua (St. Louis, Missouri); Kristina Wernes (St. Louis, Missouri); Leonardo Velazco-Cruz (St. Louis, Missouri) |
| ABSTRACT | Among the various aspects of the present disclosure is the provision of methods and compositions for the generation of functionally mature beta cells having enhanced SIX2+ activity and therapeutic benefit and uses thereof. An aspect of the present disclosure provides for a method of generating SIX2-enhanced SC-β cells. In some embodiments, the method comprises providing a population of SC-β cells (or EP cells); providing a SIX2 positive regulator; and/or incubating the population of SC-β cells and the SIX2 positive regulator. |
| FILED | Friday, November 20, 2020 |
| APPL NO | 17/778079 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/39 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0676 (20130101) Original (OR) Class C12N 2500/90 (20130101) C12N 2501/385 (20130101) C12N 2501/727 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230014658 | Seelig et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Georg Seelig (Seattle, Washington); Anna Kuchina (Seattle, Washington); Alexander B. Rosenberg (Seattle, Washington) |
| ABSTRACT | Methods of labeling or barcoding molecules within one or more portions of a plurality of cells are provided. Kits and systems for labeling or barcoding molecules within one or more portions of a plurality of cells are also provided. The methods, kits, and systems may utilize photo-controlled adapter sequences, nucleic acids tags, and/or linkers. |
| FILED | Thursday, July 14, 2022 |
| APPL NO | 17/864690 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1037 (20130101) C12N 15/1065 (20130101) Original (OR) Class C12N 15/1068 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 30/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230014787 | Johnson |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
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| INVENTOR(S) | Bankole A. Johnson (Charlottesville, Virginia) |
| ABSTRACT | Compositions and methods are provided that are useful for diagnosing, treating, and monitoring alcohol dependence and disorders, susceptibility to alcohol dependence disorders, as well as drug related dependence and disorders. The methods include treating patients with an antagonist of the serotonin receptor 5-HT3 for such disorders, wherein the patient's serotonin transporter gene SLC6A4 is known to have particular genotypes. |
| FILED | Monday, April 18, 2022 |
| APPL NO | 17/659641 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4178 (20130101) Original (OR) Class A61K 31/7048 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 1/6888 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) C12Q 2600/172 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230015276 | ZHANG et al. |
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| FUNDED BY |
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| APPLICANT(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Yi ZHANG (Boston, Massachusetts); Shogo MATOBA (Tsukuba, Japan) |
| ABSTRACT | The present invention provides methods and compostions to improve the efficiency of somatic cell nuclear transfer (SCNT) and the consequent production of nuclear transfer ESC (ntESC) and transgenic cells and/or non-human animals. More specifically, the present invention relates to the discovery that trimethylation of Histone H3-Lysine 9 (H3K9me3) in reprogramming resistant regions (RRRs) in the nuclear genetic material of donor somatic cells prevents efficient somatic cell nuclear reprogramming or SCNT. The present invention provide methods and compositions to decrease H3K9me3 in methods to improve efficacy of SCNT by exogenous or overexpression of the demethylase Kdm4 family and/or inhibiting methylation of H3K9me3 by inhibiting the histone methyltransferases Suv39h1 and/or Suv39h2. |
| FILED | Tuesday, June 14, 2022 |
| APPL NO | 17/840348 |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0273 (20130101) A01K 2227/105 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0604 (20130101) C12N 5/0606 (20130101) C12N 15/877 (20130101) Original (OR) Class C12N 15/1137 (20130101) C12N 2310/14 (20130101) C12N 2517/04 (20130101) Enzymes C12Y 201/01043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230015296 | KLIN et al. |
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| FUNDED BY |
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| APPLICANT(S) | Children's Healthcare of Atlanta, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ami KLIN (Atlanta, Georgia); Warren JONES (Decatur, Georgia) |
| ABSTRACT | Systems, devices, and methods are described for assessing the risk of developmental, cognitive, social, or mental abilities or disabilities in very young patients (e.g., in the first 2-6 months of life). Generally, the decline in visual fixation of a subject over time with respect to certain dynamic stimuli provides a marker of possible abilities or disabilities (such as ASD). The visual fixation of the subject is identified, monitored, and tracked over time through repeated eye tracking sessions, and data relating to the visual fixation is then analyzed to determine a possible increased risk certain conditions in the subject. A change in visual fixation as compared to similar visual fixation data of typically-developing subjects or to a subject's own, prior visual fixation data provides an indication of a developmental, cognitive, or mental ability or disability. |
| FILED | Tuesday, September 13, 2022 |
| APPL NO | 17/943719 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/0025 (20130101) A61B 3/113 (20130101) Original (OR) Class A61B 5/163 (20170801) A61B 5/167 (20130101) A61B 5/168 (20130101) A61B 2503/04 (20130101) A61B 2503/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230015539 | Murrough et al. |
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| FUNDED BY |
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| APPLICANT(S) | Icahn School of Medicine at Mount Sinai (New York, New York) |
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| INVENTOR(S) | James Murrough (New York, New York); Eric J. Nestler (New York, New York); Ming Hu Han (New York, New York) |
| ABSTRACT | The present invention relates to methods and compositions for the treatment of psychiatric disorders such as treatment-resistant depression (TRD) with KCNQ (also known as Kv7) channel openers. Also disclosed is a method of inducing or enhancing resilience in a patient by administration of a KCNQ channel opener, such as ezogabine. |
| FILED | Monday, December 07, 2020 |
| APPL NO | 17/781929 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/27 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/22 (20180101) A61P 25/24 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230015647 | Khan et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Javed Khan (Rockville, Maryland); Robert G. Hawley (Bethesda, Maryland); Girma M. Woldemichael (Bethesda, Maryland); Megan L. Peach (Frederick, Maryland) |
| ABSTRACT | The invention provides methods and compositions involving the compounds N′-(3,5-dimethylbenzoyl)picolinohydrazide; N′-(pyridin-2-yl)picolinohydrazide or pharmaceutically acceptable salts thereof for inhibiting the function of histone demethylases in vivo and in vitro, as well as methods for treating cancer comprising the administration of such compositions. |
| FILED | Wednesday, November 18, 2020 |
| APPL NO | 17/777552 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4402 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230015661 | Klemke et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard Klemke (La Jolla, California); Huawei Wang (La Jolla, California); Willie Pi (La Jolla, California) |
| ABSTRACT | Provided are methods for treating a disease using bioengineered enucleated cells. Also provided herein are compositions comprising enucleated cells, wherein the enucleated cells have been loaded with clinically relevant biomolecules. |
| FILED | Wednesday, September 14, 2022 |
| APPL NO | 17/944604 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/13 (20130101) Original (OR) Class A61K 38/208 (20130101) A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 2039/54 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230015736 | RAY et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | SANGEETA RAY (ELLICOTT CITY, Maryland); MARTIN G. POMPER (BALTIMORE, Maryland) |
| ABSTRACT | Prostate-specific membrane antigen targeted high-affinity agents for endoradiotherapy of prostate cancer are disclosed. |
| FILED | Monday, August 22, 2022 |
| APPL NO | 17/892203 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/0482 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 257/02 (20130101) C07D 401/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230015901 | Morin et al. |
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| FUNDED BY |
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| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen Morin (Lincoln, Nebraska); Ruiguo Yang (Lincoln, Nebraska); Karla Perez-Toralla (Lincoln, Nebraska); Mark Rose (Lincoln, Nebraska); Angel Olivera-Torres (Lincoln, Nebraska); John Kapitan (Lincoln, Nebraska); Grayson Minnick (Lincoln, Nebraska) |
| ABSTRACT | The invention provides a method for preparing an ordered cell-containing microarray, and a system for preparing an ordered cell-containing microarray. |
| FILED | Wednesday, June 15, 2022 |
| APPL NO | 17/840815 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 11/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230015942 | Lee et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | KangJu Lee (Los Angeles, California); Alireza Khademhosseini (Los Angeles, California) |
| ABSTRACT | A delivery device or patch is disclosed that includes a detachable hybrid microneedle depot (d-HMND) for cell delivery. The system includes, in one embodiment, an array of microneedles formed from an outer PLGA shell and an internal gelatin methacryloyl (GelMA)-mesenchymal stem cells (MSC) mixture (GMM). The array of microneedles project from a base substrate layer that may be flexible. The therapeutic device may be applied to a tissue site of interest and the base substrate layer is removed leaving the hybrid microneedles in the tissue at the site of application to deliver MSCs. Other stem/therapeutic cells may also be delivered with the hybrid microneedles. |
| FILED | Thursday, December 10, 2020 |
| APPL NO | 17/783265 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) A61K 47/10 (20130101) A61K 47/32 (20130101) A61K 47/36 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/0015 (20130101) Original (OR) Class A61M 2037/0046 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230016245 | Duan et al. |
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| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mengtong Duan (Pasadena, California); Mikhail G. Shapiro (Pasadena, California) |
| ABSTRACT | Disclosed herein include methods, compositions, and kits enabling expression of multiple proteins from a single mRNA with a predetermined stoichiometry. There are provided, in some embodiments, nucleic acid compositions comprising a promoter operably linked to a polynucleotide comprising a first nucleic acid unit encoding first unit payload protein(s) and a second nucleic acid unit encoding second unit payload protein(s). The first nucleic acid unit and the second nucleic acid unit can each comprise a 3′ engineered translation initiation site (eTIS) comprising a three-nucleotide tunable element immediately upstream of a start codon. The eTIS of each of the first nucleic acid unit and the second nucleic acid unit can be configured to achieve a predetermined stoichiometry of the first unit payload protein(s) and the second unit payload protein(s) in a cell or cell-like environment. |
| FILED | Friday, July 15, 2022 |
| APPL NO | 17/866240 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/223 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) Original (OR) Class C12N 2840/105 (20130101) C12N 2840/203 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230016284 | Steichen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International AIDS Vaccine Initiative, Inc. (New York, New York); The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jon Steichen (La Jolla, California); Dan Kulp (New York, New York); Xiaozhen Hu (La Jolla, California); Sergey Menis (New York, New York); William Schief (La Jolla, California); Sebastian Raemisch (La Jolla, California) |
| ABSTRACT | The invention relates to PGT121-germline-targeting designs, trimer stabilization designs, combinations of those two, trimers designed with modified surfaces helpful for immunization regimens, other trimer modifications and on development of trimer nanoparticles and methods of making and using the same. |
| FILED | Wednesday, August 11, 2021 |
| APPL NO | 17/399501 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/21 (20130101) A61K 2039/575 (20130101) Peptides C07K 14/005 (20130101) C07K 14/162 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230016424 | Burke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Martin D. Burke (Champaign, Illinois); Arun Maji (Champaign, Illinois); Jiabao Zhang (Urbana, Illinois); Su Yan (Champaign, Illinois); Yong Nian (Urbana, Illinois) |
| ABSTRACT | Disclosed are C16 amide derivatives of C2′-epi-amphotericin B (C2′epiAmB) and amphotericin B (AmB), characterized by improved clinical efficacy with reduced toxicity compared to AmB. Also disclosed are pharmaceutical compositions comprising either type of the C16 amide derivatives, and therapeutic methods of using either type of the C16 amide derivatives; and methods of making the C16 amide derivatives of C2′-epi-amphotericin B. |
| FILED | Monday, August 10, 2020 |
| APPL NO | 17/633254 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/10 (20180101) Heterocyclic Compounds C07D 493/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230016456 | Chinnaiyan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Arul Chinnaiyan (Plymouth, Michigan); John Prensner (Ann Arbor, Michigan); Matthew Iyer (Ann Arbor, Michigan) |
| ABSTRACT | The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to ncRNAs as diagnostic markers and clinical targets for prostate, lung, breast and pancreatic cancer. |
| FILED | Monday, July 18, 2022 |
| APPL NO | 17/813193 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230016581 | TYAVANAGIMATT et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SIGA TECHNOLOGIES, INC. (Corvallis, Oregon) |
| ASSIGNEE(S) | SIGA TECHNOLOGIES, INC. (Corvallis, Oregon) |
| INVENTOR(S) | Shanthakumar R. TYAVANAGIMATT (Sammamish, Washington); Kris HOLT (Colorado Springs, Colorado); Ying TAN (Millbrae, California); Melialani A.C.L.S. ANDERSON (Corvallis, Oregon); Dennis E. HRUBY (Albany, Oregon) |
| ABSTRACT | The present invention is directed to a dry suspension for reconstitution containing Tecovirimat (ST-246) powder and simethicone. The dry suspension is dispersed in water to provide an aqueous pharmaceutical suspension formulation for oral administration for treating orthopoxvirus infections and/or eczema vaccinatum. The suspension formulation exhibits excellent stability and good dissolution and has an improved taste and texture. |
| FILED | Thursday, July 14, 2022 |
| APPL NO | 17/864909 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/16 (20130101) A61K 9/0053 (20130101) A61K 9/0095 (20130101) A61K 31/403 (20130101) Original (OR) Class A61K 47/26 (20130101) A61K 47/34 (20130101) A61K 47/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230016609 | Karathanasis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Efstathios Karathanasis (Solon, Ohio); Watuthentrige Pubudu M. Peiris (Twinsburg, Ohio); Vindya Perera (Hudson, Ohio); Lisa Bauer (Sandusky, Ohio) |
| ABSTRACT | A system for delivering a therapeutic agent to cell or tissue of a subject includes a mesoporous silica iron oxide nanoparticle with one or more therapeutic agents that are contained in a mesoporous silica layer of the nanoparticle and a remote radiofrequency (RF) energy source for applying RF energy to the nanoparticle effective to release the one or more therapeutic agents from the nanoparticle by mechanical tumbling and/or vibration of the nanoparticle, wherein release of the one or more therapeutic agents not caused by a hyperthermic response of the nanoparticle to the RF energy. |
| FILED | Tuesday, March 01, 2022 |
| APPL NO | 17/683803 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0009 (20130101) A61K 9/0019 (20130101) A61K 9/5115 (20130101) A61K 31/495 (20130101) A61K 31/519 (20130101) A61K 31/704 (20130101) A61K 31/7068 (20130101) A61K 41/0028 (20130101) Original (OR) Class A61K 47/6923 (20170801) A61K 47/6929 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230017126 | Silverman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois); Chapman University (Orange, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard B. Silverman (Winnetka, Illinois); Sun Yang (Lake Forest, California) |
| ABSTRACT | Disclosed herein are methods and compositions for administering immunotherapy to a subject in need thereof and for treating a subject in need thereof, where in the methods the subject is administered an effective amount of an inhibitor of nNOS for inducing an immunotherapeutic response in the subject and for treating the subject. The disclosed methods and composition may be utilized for treating a subject having a cell proliferative disease or disorder such as melanoma. |
| FILED | Monday, September 12, 2022 |
| APPL NO | 17/942928 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) Original (OR) Class A61K 31/381 (20130101) A61K 31/495 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230017196 | Jain et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VigNet Incorporated (Fairfax, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Praduman Jain (Fairfax, Virginia); Dave Klein (Oakton, Virginia); Neeta Jain (Fairfax, Virginia); Yue Cao (Vienna, Virginia) |
| ABSTRACT | In some implementations, a system enables an administrator to customize a set of rules to dynamically adjust the configuration and output of an application provided to users. A configuration interface for setting rules that dynamically adjust output of an application is provided. Data indicating one or more rules are received through the configuration interface. Activity data indicating user interaction with the application or sensor data for at least some of a plurality of users of the application are then received from multiple client devices. A determination relating to the activity data satisfying at least one condition or trigger is then made. Instructions to adjust output of the application according to one or more system actions of the one or more rules are then communicated to client devices associated with the users in the first subset of the plurality of users. |
| FILED | Friday, September 16, 2022 |
| APPL NO | 17/947064 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/04817 (20130101) G06F 3/04842 (20130101) G06F 8/60 (20130101) Original (OR) Class G06F 8/61 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/63 (20180101) G16H 40/67 (20180101) Transmission of Digital Information, e.g Telegraphic Communication H04L 41/0803 (20130101) H04L 67/01 (20220501) H04L 67/06 (20130101) H04L 67/025 (20130101) H04L 67/34 (20130101) H04L 67/53 (20220501) H04L 67/125 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230017266 | Levine et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| ASSIGNEE(S) | THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| INVENTOR(S) | Stewart J. Levine (North Potomac, Maryland); Xianglan Yao (Gaithersburg, Maryland); Maryann Kaler (Bethesda, Maryland); Alan T. Remaley (Bethesda, Maryland); Amisha V. Barochia (North Potomac, Maryland) |
| ABSTRACT | A method of treating an asthmatic subject is provided. The method includes determining serum level of serum amyloid A (SAA) in the subject; comparing the serum level with a pre-determined threshold; and administering to the subject a therapeutically effective amount of a COX-2 inhibitor if the serum level is greater than or equal to the threshold. |
| FILED | Thursday, December 03, 2020 |
| APPL NO | 17/781530 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/42 (20130101) A61K 31/167 (20130101) A61K 31/192 (20130101) A61K 31/196 (20130101) A61K 31/365 (20130101) A61K 31/415 (20130101) A61K 31/616 (20130101) A61K 31/635 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/06 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) Original (OR) Class G01N 2800/52 (20130101) G01N 2800/122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230017523 | Krishnan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Siddharth Krishnan (Cambridge, Massachusetts); Suman Bose (Cambridge, Massachusetts); Nima Khatib (Somerville, Massachusetts); Matthew Bochenek (Cambridge, Massachusetts); Robert S. LANGER (Newton, Massachusetts); Daniel Anderson (Framingham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Siddharth Krishnan (Cambridge, Massachusetts); Suman Bose (Cambridge, Massachusetts); Nima Khatib (Somerville, Massachusetts); Matthew Bochenek (Cambridge, Massachusetts); Robert S. LANGER (Newton, Massachusetts); Daniel Anderson (Framingham, Massachusetts) |
| ABSTRACT | A bioelectronic device houses therapeutic cells and is configured to be implanted in a host. The device includes an electrochemical cell that produces oxygen gas from water when a voltage is applied. The oxygen gas produced by the electrochemical cell is stored in a gas diffusion chamber in the device. The therapeutic cells in a cell housing chamber in the device receive oxygen gas from the gas diffusion chamber to help keep the cells alive and functioning when the device is implanted in a low oxygen environment. The device receives power wirelessly. |
| FILED | Friday, May 06, 2022 |
| APPL NO | 17/738200 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 35/22 (20130101) A61K 35/39 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/00 (20130101) Original (OR) Class A61M 2202/09 (20130101) A61M 2202/0208 (20130101) A61M 2205/051 (20130101) A61M 2205/0238 (20130101) A61M 2205/3303 (20130101) A61M 2205/8206 (20130101) A61M 2207/00 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230017557 | BATEMAN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | RANDALL BATEMAN (St. Louis, Missouri); NICOLAS BARTHELEMY (St. Louis, Missouri) |
| ABSTRACT | The present disclosure provides methods to quantify tau phosphorylation at specific amino acid residues, using blood samples, to predict time to onset of mild cognitive impairment due to Alzheimer's disease, stage Alzheimer's disease, guide treatment decisions, select subjects for clinical trials, and evaluate the clinical efficacy of certain therapeutic interventions. |
| FILED | Thursday, September 10, 2020 |
| APPL NO | 17/642170 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/34 (20130101) G01N 1/405 (20130101) G01N 1/4055 (20130101) G01N 33/6842 (20130101) Original (OR) Class G01N 33/6896 (20130101) G01N 2001/4061 (20130101) G01N 2440/14 (20130101) G01N 2800/2821 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230017637 | Wrobel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Biohaven Therapeutics Ltd. (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jay Edward Wrobel (Lawrenceville, New Jersey); Allen B. Reitz (Lansdale, Pennsylvania); Jeffery Claude Pelletier (Lafayette Hill, Pennsylvania); Garry Robert Smith (Royersford, Pennsylvania); Haiyan Bian (Princeton, New Jersey) |
| ABSTRACT | Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole. Prodrugs of riluzole have enhanced stability to hepatic metabolism and are delivered into systemic circulation by oral administration, and then cleaved to release riluzole in the plasma via either an enzymatic or general biophysical release process. |
| FILED | Monday, July 05, 2021 |
| APPL NO | 17/367484 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/006 (20130101) A61K 9/1617 (20130101) A61K 9/2004 (20130101) A61K 31/428 (20130101) Original (OR) Class A61K 31/454 (20130101) A61K 31/496 (20130101) A61K 31/5377 (20130101) A61K 38/05 (20130101) A61K 38/06 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) A61P 25/28 (20180101) Heterocyclic Compounds C07D 277/82 (20130101) C07D 417/12 (20130101) Peptides C07K 5/0806 (20130101) C07K 5/0808 (20130101) C07K 5/0812 (20130101) C07K 5/06026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230017712 | Baum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | OAK CREST INSTITUTE OF SCIENCE (Monrovia, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Marc M. Baum (Altadena, California); John A. Moss (Sierra Madre, California) |
| ABSTRACT | This disclosure relates to the use of an implantable device to deliver biologically active compounds at a controlled rate for an extended period of time and methods of manufactures thereof. The device is biocompatible and biostable, and is useful as an implant in patients (humans and animals) for the delivery of appropriate bioactive substances to tissues or organs. |
| FILED | Wednesday, November 25, 2020 |
| APPL NO | 17/780420 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) Original (OR) Class A61K 9/0036 (20130101) A61K 9/4808 (20130101) A61K 9/4816 (20130101) A61K 31/517 (20130101) A61K 31/675 (20130101) A61K 31/7048 (20130101) A61K 47/14 (20130101) A61K 47/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230017777 | Pun et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington); Seattle Children's Hospital d/b/a Seattle Children's Research Institute (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington); Seattle Children's Hospital d/b/a Seattle Children's Research Institute (Seattle, Washington) |
| INVENTOR(S) | Suzie Hwang Pun (Seattle, Washington); Meilyn Sylvestre (Seattle, Washington); Nataly Kacherovsky (Seattle, Washington); Emmeline Cheng (Seattle, Washington); Ian Cardle (Seattle, Washington); Chris Saxby (Seattle, Washington) |
| ABSTRACT | Provided herein are compositions comprising aptamers that specifically bind monocytes and/or macrophage and methods for their use. These aptamer compositions can be used in methods for isolating and/or enriching monocytes and/or macrophages or depleting cell populations of monocytes and/or macrophages. Further provided are methods of using the aptamers or cell populations generated using them in the methods disclosed herein for therapies and/or drug delivery. |
| FILED | Friday, June 24, 2022 |
| APPL NO | 17/849513 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0645 (20130101) C12N 15/115 (20130101) Original (OR) Class C12N 15/1048 (20130101) C12N 15/1065 (20130101) C12N 2310/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230017785 | Brodsky et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert A. Brodsky (Brooklandville, Maryland); Xuan Yuan (Kingsville, Maryland) |
| ABSTRACT | The present invention relates generally to the field of disorders of complement activation. More specifically, the present invention provides methods and compositions useful for identifying patients having a complement-mediated disease that could benefit from treatment with complement inhibitors. As described herein, the present invention utilizes patient sera and flow cytometry in the companion diagnostic assay. More specifically, the present invention comprises evaluating complement activity via cell surface deposition of C5b-9 and, in further embodiments, complement-dependent cell killing (the modified Ham assay) using patient sera. |
| FILED | Monday, December 07, 2020 |
| APPL NO | 17/782742 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) Original (OR) Class G01N 2333/4716 (20130101) G01N 2333/96433 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230018080 | Baric et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ralph Baric (Haw River, North Carolina); Ellen Young (Hillsborough, North Carolina); Jennifer Munt (Durham, North Carolina) |
| ABSTRACT | The present invention provides compositions and methods of use comprising a chimeric dengue virus E glycoprotein comprising a dengue virus E glycoprotein backbone, which comprises amino acid substitutions that may introduce an epitope that is recognized by an antibody from a dengue virus serotype that is different from the dengue virus serotype of the dengue virus E glycoprotein backbone. |
| FILED | Friday, November 20, 2020 |
| APPL NO | 17/778055 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Peptides C07K 14/1825 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230018405 | Hogan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Quinn H. Hogan (Milwaukee, Wisconsin); Hongwei Yu (Milwaukee, Wisconsin) |
| ABSTRACT | Aspects of the disclosure relate to constructs comprising one or more Cav3.2 inhibitory polypeptide that blocks Cav3.2 T-type calcium channel activity and nociceptive dorsal root ganglion (DRG) neuron excitation. Also provided herein are methods for treating pain in a subject in need thereof. In particular, provided herein are methods comprising administering Cav3.2 inhibitory peptide constructs to a dorsal root ganglion of the subject, whereby expression of the Cav3.2 inhibitory polypeptides partially or fully inhibits Cav3.2 T-type calcium channel activity in the DRG. |
| FILED | Wednesday, June 29, 2022 |
| APPL NO | 17/853296 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 15/861 (20130101) C12N 2750/14142 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230018417 | Ofori-Acquah et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Shire Human Genetic Therapies, Inc. (Lexington, Massachusetts); University of Pittsburgh-Of The Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Solomon Fiifi Ofori-Acquah (Pittsburgh, Pennsylvania); Samit Ghosh (Pittsburgh, Pennsylvania); Joseph Sypek (Lexington, Massachusetts); Bohong Zhang (Lexington, Massachusetts); Xiuxia Sun (Lexington, Massachusetts); Clark Q. Pan (Lexington, Massachusetts); Daniel Minard Lajole (Lexington, Massachusetts); Chuan Shen (Lexington, Massachusetts) |
| ABSTRACT | The present invention provides, among other things, methods and compositions for making and using recombinant heme oxygenase for treating sickle cell disease. In some embodiments, recombinant heme oxygenase proteins are truncation variants, or Fc fusion proteins with increased half-life and/or reduced aggregation. |
| FILED | Friday, July 24, 2020 |
| APPL NO | 17/623503 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/44 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/06 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0071 (20130101) C12N 15/62 (20130101) Enzymes C12Y 114/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230018615 | Micalizio |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Glenn C. Micalizio (Hanover, New Hampshire) |
| ABSTRACT | Methods for producing enantiodefined polycyclic compounds, particularly tetracyclic compounds, are provided. More particularly, synthetic methods for producing biologically active enantiodefined steroidal compositions of both natural (“nat-”) and unnatural (“ent-”) absolute stereochemistry are provided. An exemplary method for manufacturing a tetracyclic compound comprises a step of forming a hydrindane intermediate through coupling of a suitably functionalized enyne with a suitably functionalized alkyne and subsequently performing an intramolecular ring-closing reaction to form the tetracyclic compound. Steroidal compounds obtained by this method and methods of using such steroidal compounds in human and/or animal therapeutics and medicines are also provided. |
| FILED | Wednesday, August 10, 2022 |
| APPL NO | 17/818873 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Steroids C07J 11/00 (20130101) Original (OR) Class C07J 15/00 (20130101) C07J 75/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230018705 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James K. Liu (Lutz, Florida); Daniel Abate-Daga (Tampa, Florida); Cecilia Ramello (Tampa, Florida) |
| ABSTRACT | Compositions and methods are disclosed for targeted treatment of lung cancer-derived metastatic brain tumors. In particular, tumor targeting agents comprising targeting peptides are disclosed that can target a payload, such as a therapeutic or diagnostic agent, to lung cancer-derived metastatic brain tumors. Chimeric antigen receptor (CAR) polypeptides are disclosed that can be used with adoptive cell transfer to target and kill lung cancer-derived metastatic brain tumors. |
| FILED | Thursday, October 17, 2019 |
| APPL NO | 17/282257 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 39/3955 (20130101) A61K 47/64 (20170801) Original (OR) Class A61K 47/65 (20170801) Peptides C07K 14/7051 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230018807 | Pandolfino et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John Erik Pandolfino (Wilmette, Illinois); Neelesh Ashok Patankar (Buffalo Grove, Illinois); Shashank Acharya (Evanston, Illinois); Sourav Halder (Evanston, Illinois); Wenjun Kou (Rockford, Illinois); Peter James Kahrilas (Chicago, Illinois); Dustin Allan Carlson (Chicago, Illinois) |
| ABSTRACT | A fluid mechanics-based analysis tool is implemented to compute pressure field data, fluid velocity data, and/or muscular work data in a lumen or other tubular organ or structure from planimetry and pressure data (e.g., measured using a balloon dilation or other planimetry catheter). In this way, flow data can be estimated, which are otherwise insensible from current planimetry catheter technologies due to economic and/or manufacturing limitations. |
| FILED | Thursday, November 19, 2020 |
| APPL NO | 17/778340 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1076 (20130101) A61B 5/6853 (20130101) Original (OR) Class Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230018989 | Gregory |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Richard I. Gregory (Brookline, Massachusetts) |
| ABSTRACT | Provided herein are method of treating cancer using agents that inhibit the interaction between Methyltransferase like 3 (METTL3) and Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3h), and optionally agents that inhibit Bromodomain-containing protein 4 (BRD4). The present disclosure demonstrates the topology of individual polyribosomes with single METTL3 foci found in close proximity to 5′ cap-binding proteins, revealing a previously unknown direct physical and functional interaction between METTL3 and the eukaryotic translation initiation factor 3 subunit h (eIF3h). |
| FILED | Thursday, July 02, 2020 |
| APPL NO | 17/624117 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/45 (20130101) A61K 38/1709 (20130101) Peptides C07K 16/18 (20130101) C07K 16/40 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1137 (20130101) C12N 2310/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230019085 | BRADLEY et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Linda M. BRADLEY (San Diego, California); Roberto TINOCO (San Diego, California) |
| ABSTRACT | The present invention relates to the seminal discovery that P-selectin glycoprotein ligand-1 (PSGL-1) modulates the immune system and immune responses. Specifically, the present invention provides PSGL-1 agonists and antagonists which increase the survival of multifunctional T cells and viral clearance. The present invention further provides methods of treating infectious diseases, cancer and immune and inflammatory diseases and disorders using a PSGL-1 modulator. |
| FILED | Tuesday, June 21, 2022 |
| APPL NO | 17/845812 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 14/70596 (20130101) C07K 16/2854 (20130101) Original (OR) Class C07K 16/2896 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230019129 | Turner, JR. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana); Assembly Biosciences, Inc. (Carmel, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana); Assembly Biosciences, Inc. (Carmel, Indiana) |
| INVENTOR(S) | William W. Turner, JR. (Bloomington, Indiana); Lee Daniel Arnold (Bloomington, Indiana); Hans Maag (Kleines Wiesenthal, Germany); Adam Zlotnick (Bloomington, Indiana) |
| ABSTRACT | The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound. |
| FILED | Thursday, January 21, 2021 |
| APPL NO | 17/154721 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) A61K 31/553 (20130101) A61K 31/554 (20130101) A61K 31/5513 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/12 (20180101) Heterocyclic Compounds C07D 223/20 (20130101) C07D 243/38 (20130101) C07D 281/14 (20130101) C07D 281/16 (20130101) C07D 401/12 (20130101) C07D 403/12 (20130101) C07D 413/12 (20130101) C07D 417/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230019342 | Heath et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James R. Heath (Pasadena, California); Arundhati Nag (Pasadena, California); Samir Das (Pasadena, California); Joseph O. Varghese (Pasadena, California); Ryan K. Henning (Pasadena, California) |
| ABSTRACT | The present application provides stable peptide-based Akt capture agents and methods of use as detection and diagnosis agents and in the treatment of diseases and disorders. The application further provides methods of manufacturing Akt capture agents using iterative on-bead in situ click chemistry. |
| FILED | Monday, June 27, 2022 |
| APPL NO | 17/850743 |
| CURRENT CPC | Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/582 (20130101) G01N 33/5748 (20130101) Original (OR) Class G01N 2333/91205 (20130101) G01N 2440/14 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230019387 | Basser et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Peter J. Basser (Washington, District of Columbia); Dan H. Benjamini (Rockville, Maryland) |
| ABSTRACT | Multi-dimensional spectra associated with a specimen are reconstructed using lower dimensional spectra as constraints. For example, a two-dimensional spectrum associated with diffusivity and spin-lattice relaxation time is obtained using one-dimensional spectra associated with diffusivity and spin-lattice relaxation time, respectively, as constraints. Data for a full two dimensional spectrum are not acquired, leading to significantly reduced data acquisition times. |
| FILED | Wednesday, July 13, 2022 |
| APPL NO | 17/863846 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/448 (20130101) G01R 33/465 (20130101) Original (OR) Class G01R 33/4625 (20130101) G01R 33/56341 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230019488 | Bash et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE U.S.A, as represented by the Secretary, Department of Health and Human Services (Silver Spring, Maryland) |
| ASSIGNEE(S) | THE U.S.A, as represented by the Secretary, Department of Health and Human Services (Silver Spring, Maryland) |
| INVENTOR(S) | Margaret Bash (Silver Spring, Maryland); Kathryn Matthias (Silver Spring, Maryland) |
| ABSTRACT | Immunogenic compositions are disclosed that include Neisseria meningitidis microvesicles, such as outer membrane vesicles (OMV) and/or blebs, from PorA−PorB− Neisseria, such as PorA−PorB−ampM− Neisseria meningitidis. These immunogenic compositions are of use to induce an immune response to Neisseria, including Neisseria meningitidis and Neisseria gonorrhea. |
| FILED | Friday, September 02, 2022 |
| APPL NO | 17/929415 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/095 (20130101) Original (OR) Class Peptides C07K 14/22 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230019568 | BAZAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Supervisors of Louisiana State University and Agriculture and Mechanical College (Baton Rouge, Louisiana); University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Haydee BAZAN (New Orleans, Louisiana); Nicolas G. BAZAN (New Orleans, Louisiana); Thang L. PHAM (New Orleans, Louisiana); Bokkyoo JUN (Geismar, Louisiana); Nicos A. PETASIS (Los Angeles, California) |
| ABSTRACT | This invention is directed to compositions and methods for treating cornea pathologies. Specifically, aspects of the invention are drawn to a biomolecule and methods of using the same to treat cornea pathologies that affect tissue innervation. |
| FILED | Wednesday, December 09, 2020 |
| APPL NO | 17/783770 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/0048 (20130101) A61K 31/202 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230019818 | Amelio et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Antonio Amelio (Pittsboro, North Carolina); Chad V. Pecot (Pittsboro, North Carolina) |
| ABSTRACT | The present invention relates to methods of diagnosing and/or treating head and neck squamous cell carcinoma (HNSCC) in a subject. The present invention further relates to methods of diagnosing and/or treating head and neck squamous cell carcinoma (HNSCC) in a subject, wherein the subject has been diagnosed as being positive for human papillomavirus (HPV |
| FILED | Tuesday, June 28, 2022 |
| APPL NO | 17/851545 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6851 (20130101) C12Q 1/6886 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57407 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230019849 | GOTTSCHALK et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (Memphis, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephan GOTTSCHALK (Memphis, Tennessee); Mireya VELASQUEZ (Memphis, Tennessee); Abdullah FREIWAN (Memphis, Tennessee); Abishek VAIDYA (Memphis, Tennessee); Deanna LANGFITT (Memphis, Tennessee) |
| ABSTRACT | Methods for preparing CD7-negative, CD3-positive T cells, which optionally express a chimeric antigen receptor, are provided as is a method of using such cells in a method for treating cancer, in particular a CD7+ cancer. In one aspect, the invention provides a method for preparing a population of CD7-negative, CD3-positive T cells by (a) performing a first selection by depleting, from a population of primary immune cells, cells that express CD7 thereby generating a population of CD7-negative cells; (b) performing a second selection by enriching, from the population of CD7-negative cells, T cells that express CD3 thereby generating a population of CD7-negative and CD3-positive T cells, and (c) incubating the population of CD7-negative and CD3-positive T cells in a culture vessel under stimulating conditions, thereby generating stimulated CD7-negative, CD3-positive T cells. |
| FILED | Friday, December 04, 2020 |
| APPL NO | 17/783040 |
| CURRENT CPC | Separation B01D 15/3809 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0087 (20130101) C12N 5/0636 (20130101) Original (OR) Class C12N 2501/2307 (20130101) C12N 2501/2315 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230019924 | Reiserer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ronald S. Reiserer (Nashville, Tennessee); Gregory B. Gerken (Nashville, Tennessee); David K. Schaffer (Nashville, Tennessee); John P. Wikswo (Brentwood, Tennessee) |
| ABSTRACT | A continuous automated perfusion culture analysis system (CAPCAS) comprises one or more fluidic systems configured to operate large numbers of biodevices in parallel. Each fluidic system comprises an input reservoir plate for receiving media; a biodevice plate comprising an array of biodevices fluidically coupled to the input reservoir plate, configured such that each biodevice has independent media delivery, fluid removal, stirring, and gas control, and each biodevice is capable of continuously receiving the media from the input reservoir plate; and an output plate fluidically coupled to the biodevice plate for real-time analysis and sampling. The operations of the CAPCAS are automated and computer-controlled wirelessly. The CAPCAS can also be used for abiotic and biotic chemical synthesis processes. |
| FILED | Monday, September 19, 2022 |
| APPL NO | 17/947302 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/08 (20130101) C12M 23/10 (20130101) C12M 23/12 (20130101) C12M 23/16 (20130101) C12M 23/50 (20130101) C12M 23/58 (20130101) C12M 27/02 (20130101) C12M 27/12 (20130101) C12M 29/10 (20130101) Original (OR) Class C12M 35/02 (20130101) C12M 35/04 (20130101) C12M 41/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230020036 | HUBBS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NEUROCYCLE THERAPEUTICS, INC. (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jed HUBBS (San Diego, California); Matthew TOCZKO (San Diego, California) |
| ABSTRACT | Disclosed herein are GABAA receptor modulators and compositions comprising GABAA receptor modulators for treatment of epileptic conditions. Also disclosed herein are methods of treating epileptic conditions in a subject by administering a GABAA receptor modulators or composition as described herein. |
| FILED | Friday, October 23, 2020 |
| APPL NO | 17/770794 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/53 (20130101) A61K 31/5517 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/08 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230020192 | PRAKASH et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | IONIS PHARMACEUTICALS, INC. (Carlsbad, California); BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | IONIS PHARMACEUTICALS, INC. (Carlsbad, California); BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Thazha P. PRAKASH (Carlsbad, California); Frank RIGO (Carlsbad, California); David COREY (Dallas, Texas) |
| ABSTRACT | Disclosed herein are compounds and methods for modulating C9orf72 transcript. Such compounds and methods are useful to treat, prevent, or ameliorate neurodegenerative diseases in an individual in need thereof. |
| FILED | Friday, February 04, 2022 |
| APPL NO | 17/665348 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/712 (20130101) Original (OR) Class A61K 31/7115 (20130101) A61K 31/7125 (20130101) A61K 48/0066 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) A61P 25/28 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2310/113 (20130101) C12N 2310/345 (20130101) C12N 2310/346 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230020195 | Kanick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen Chad Kanick (Lebanon, New Hampshire); Brian William Pogue (Hanover, New Hampshire); Keith D. Paulsen (Hanover, New Hampshire); Jonathan T. Elliott (West Lebanon, New Hampshire); David M. McClatchy, III (Hanover, New Hampshire); Venkataramanan Krishnaswamy (Lebanon, New Hampshire) |
| ABSTRACT | A method for determining sub-diffuse scattering parameters of a material includes illuminating the material with structured light and imaging remission by the material of the structured light. The method further includes determining, from captured remission images, sub-diffuse scattering parameters of the material. A structured-light imaging system for determining sub-diffuse scattering parameters of a material includes a structured-light illuminator, for illuminating the material with structured light of periodic spatial structure, and a camera for capturing images of the remission of the structured light by the material. The structured-light imaging system further includes an analysis module for processing the images to quantitatively determine the sub-diffuse scattering parameters. A software product includes machine-readable instructions for analyzing images of remission of structured light by a material to determine sub-diffuse scattering parameters of the material. |
| FILED | Tuesday, September 20, 2022 |
| APPL NO | 17/948434 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0075 (20130101) Original (OR) Class A61B 2576/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230020356 | Gonsky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rebecca Gonsky (Los Angeles, California); Stephan R. Targan (Santa Monica, California) |
| ABSTRACT | Described herein are methods and systems for identifying subpopulations of patients having Crohn's disease, including populations at risk of developing structuring or other severe disease, and populations susceptible to success or failure with surgical intervention. Further provided are therapies useful for treating subpopulations of patients having Crohn's disease. |
| FILED | Friday, May 28, 2021 |
| APPL NO | 17/334109 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230020545 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeannie T. Lee (Boston, Massachusetts); Anand Minajigi (Boston, Massachusetts); Lieselot Carrette (Beernem, Belgium) |
| ABSTRACT | Methods for reactivating genes on the inactive X chromosome that include administering one or both of a DNA methyltransferase (DNMT) Inhibitor and/or a topoisomerase inhibitor, e.g., etoposide and/or 5′-azacytidine (aza), optionally in combination with an inhibitor of XIST RNA and/or an Xist-interacting protein, e.g., a chromatin-modifying protein, e.g., a small molecule or an inhibitory nucleic acid (such as a small inhibitory RNA (siRNAs) or antisense oligonucleotide (ASO)) that targets XIST RNA and/or a gene encoding an Xist-interacting protein, e.g., a chromatin-modifying protein. |
| FILED | Friday, March 26, 2021 |
| APPL NO | 17/214320 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/90 (20130101) C12N 9/1007 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/20 (20170501) C12N 2310/113 (20130101) C12N 2310/531 (20130101) C12N 2310/3231 (20130101) C12N 2320/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/156 (20130101) Enzymes C12Y 201/01037 (20130101) C12Y 599/01002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230020682 | Viola et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HEMOSONICS, LLC (Charlottesville, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Francesco Viola (Chapel Hill, North Carolina); Timothy Higgins (Charlottesville, Virginia); Andrew Homyk (Charlottesville, Virginia); F. Scott Corey (Baltimore, Maryland); Franklin F. Regan, IV (Charlottesville, Virginia); William F. Walker (Charlottesville, Virginia); David Bryant (Charlottesville, Virginia); Thomas Givens (Rougemont, Virginia); Cynthia Ann Lloyd (Durham, North Carolina) |
| ABSTRACT | A disposable system, in some embodiments, includes a multi-channel or multi-chamber test cartridge device configured to operate with a testing system for evaluation of hemostasis in a subject by in vitro evaluation of a test sample from the subject. The disposable system, in some embodiments, is configured to interrogate the test sample to evaluate clot stiffness, strength, or other mechanical properties of the test sample to assess the function of various physiological processes occur during coagulation and/or dissolution of the resulting clot. |
| FILED | Friday, June 17, 2022 |
| APPL NO | 17/843505 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502 (20130101) B01L 2300/0825 (20130101) B01L 2300/0838 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/86 (20130101) G01N 33/4905 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230020862 | COULOMBE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kareen L. K. COULOMBE (Pawtucket, Rhode Island); Stephanie ROSER (Florham Park, New Jersey); Fabiola MUNARIN (Smithfield, Rhode Island); Alicia MINOR (Providence, Rhode Island) |
| ABSTRACT | The invention provides a highly versatile system to promote vascularization in ischemic tissue. The system is composed of a fully defined, customizable hydrogel loaded with a potent cocktail of proangiogenic growth factors. The hydrogel's mechanical, degradation, and factor release behavior can be tailored to the specifications of any given target tissue or ischemic disease state. The growth factor cocktail can be optimized for maximal vessel density or size to meet the perfusion specifications required by the tissue. The embodiments of the disclosure concern methods and compositions of the system, with examples of preparation for both injectable and implantable delivery modes. |
| FILED | Tuesday, July 12, 2022 |
| APPL NO | 17/862962 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) Original (OR) Class A61K 38/30 (20130101) A61K 38/1825 (20130101) A61K 38/1858 (20130101) A61K 38/1866 (20130101) A61K 47/36 (20130101) A61K 47/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230020999 | RUBINSTEIN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Paul Rubinstein (Chicago, Illinois); Seagen Inc. (Bothell, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul RUBINSTEIN (Chicago, Illinois); Nancy WHITING (Bothell, Washington); Ryan Alan HEISER (Bothell, Washington); Bryan Matthew GROGAN (Snohomish, Washington); Markus Puhlmann (Kirkland, Washington) |
| ABSTRACT | The disclosure provides anti-CD30 antibody-drug conjugates and methods of using the same to increase CD4+ T-cell lymphocyte count or treat 1-IIV infection. The disclosure also provides articles of manufacture or kits comprising said antibody drug-conjugates that bind to CD30 for increasing CD4+ T-cell lymphocyte count or treating HIV infection. |
| FILED | Wednesday, November 04, 2020 |
| APPL NO | 17/772105 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/64 (20170801) A61K 47/65 (20170801) A61K 47/6803 (20170801) Original (OR) Class A61K 47/6849 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230021091 | DESAI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Encodia, Inc. (San Diego, California) |
| ASSIGNEE(S) | Encodia, Inc. (San Diego, California) |
| INVENTOR(S) | Kevin DESAI (San Diego, California); Kevin L. Gunderson (San Diego, California); Robert C. James (San Diego, California); Lei Shi (San Diego, California); Stephen Verespy, III (San Diego, California) |
| ABSTRACT | Provided herein are modified cleavases for removing amino acids from peptides, polypeptides, and proteins. Also provided are methods of using the modified cleavases for treating polypeptides, and kits comprising the modified cleavase. In some embodiments, the methods and the kits also include other components for macromolecule sequencing and/or analysis. |
| FILED | Monday, June 27, 2022 |
| APPL NO | 17/850516 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/485 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230021224 | MIN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York); ST. JUDE CHILDREN'S RESEARCH HOSPITAL (Memphis, Tennessee) |
| ASSIGNEE(S) | MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York); ST. JUDE CHILDREN'S RESEARCH HOSPITAL (Memphis, Tennessee) |
| INVENTOR(S) | Jaeki MIN (Memphis, Tennessee); Daniel C. SCOTT (Marion, Arkansas); Deepak BHASIN (Cordova, Tennessee); Brenda A. SCHULMAN (Memphis, Tennessee); Bhuvanesh SINGH (Old Westbury, New York); Jared T. HAMMILL (Memphis, Tennessee); R. Kiplin GUY (Memphis, Tennessee) |
| ABSTRACT | In one aspect, the invention relates to substituted 1-phenyl-3-(piperidin-4-yl)urea analogs, derivatives thereof, and related compounds, which are useful as inhibitors of the DCN1-UBC12 interaction inhibitors of DCN1-mediated cullin-RING ligase activity, methods of making same, pharmaceutical compositions comprising same, methods of treating disorders using the disclosed compounds and compositions, methods of treating disorders associated with a DCN1-UBC12 interaction dysfunction, methods of treating disorders associated with a DCN1-mediated cullin-RING ligase activity dysfunction, methods of male contraception comprising the disclosed compounds and compositions, and kits comprising the disclosed compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Thursday, September 09, 2021 |
| APPL NO | 17/470678 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/17 (20130101) A61K 31/437 (20130101) A61K 31/451 (20130101) A61K 31/454 (20130101) A61K 31/506 (20130101) A61K 31/4525 (20130101) A61K 31/4545 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 15/16 (20180101) A61P 31/04 (20180101) A61P 31/12 (20180101) Heterocyclic Compounds C07D 211/58 (20130101) C07D 401/04 (20130101) C07D 401/06 (20130101) C07D 401/12 (20130101) C07D 405/06 (20130101) C07D 405/12 (20130101) C07D 409/14 (20130101) C07D 417/04 (20130101) C07D 417/06 (20130101) C07D 471/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230021307 | Kim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Servic (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | June-Hong Kim (North Bethesda, Maryland); Robert J. Lederman (Chevy Chase, Maryland); Ozgur Kocaturk (Rockville, Maryland) |
| ABSTRACT | Devices and methods are disclosed for the treatment or repair of regurgitant cardiac valves, such as a mitral valve. An annuloplasty device can be placed in the coronary sinus to reshape the mitral valve and reduce mitral valve regurgitation. A protective device can be placed between the annuloplasty device and an underlying coronary artery to inhibit compression of the underlying coronary artery by the annuloplasty device in the coronary sinus. In addition, the protective device can inhibit compression of the coronary artery from inside the heart, such as from a prosthetic mitral valve that exerts radially outward pressure toward the coronary artery. The annuloplasty device can also create an artificial inner ridge or retaining feature projecting into the native mitral valve region to help secure a prosthetic mitral valve. |
| FILED | Tuesday, May 26, 2020 |
| APPL NO | 16/882896 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2451 (20130101) Original (OR) Class A61F 2210/0014 (20130101) A61F 2220/0075 (20130101) A61F 2230/0045 (20130101) A61F 2250/001 (20130101) A61F 2250/0004 (20130101) A61F 2250/0037 (20130101) A61F 2250/0065 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/0041 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20230012557 | Small |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Scott L. Small (Newberry, Indiana) |
| ABSTRACT | Provided is a trunk cable installation verification tool. The device comprises a body that attaches to a stuffing or fitting tube, a level tube, a magnet, and a tolerance indicator for aligning a cable. The body is shaped to fit the contours of the fitting tube for ease of attachment thereto. A magnet secures the body to the fitting tube for quick and non-permanent attachment. The tolerance indicator is preferably a V-shaped protrusion or a notch that is aligned with the centreline of the fitting tube and is used to ensure proper alignment of the cable, which is confirmed with a cable identification line. The verification tool ensures proper cable alignment and reduces/prevents stress on the bond line between cable outer jacket and the epoxy, thereby preventing premature cable failure and extending the maintenance intervals required to replace damaged cables. |
| FILED | Friday, July 15, 2022 |
| APPL NO | 17/865759 |
| CURRENT CPC | Installation of Electric Cables or Lines, or of Combined Optical and Electric Cables or Lines H02G 3/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230012710 | AMARNATH et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Aporva AMARNATH (Ann Arbor, Michigan); Augusto VEGA (Yorktown Heights, New York); Alper BUYUKTOSUNOGLU (Yorktown Heights, New York); Hubertus FRANKE (Yorktown Heights, New York); John-David WELLMAN (Yorktown Heights, New York); Pradip BOSE (Yorktown Heights, New York) |
| ABSTRACT | Tasks of directed acyclic graphs (DAGs) may be dynamically scheduled based on a plurality of constraints and conditions, task prioritization policies, task execution estimates, and configurations of a heterogenous system. A machine learning component may be initialized to dynamically schedule the tasks of the DAGs. |
| FILED | Wednesday, July 14, 2021 |
| APPL NO | 17/305784 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/485 (20130101) G06F 9/4881 (20130101) Original (OR) Class G06F 9/44505 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230013068 | Lin |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Bioenno Tech LLC (Santa Ana, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhigang Lin (Santa Ana, California) |
| ABSTRACT | High voltage, high-ionic-conductivity, fire resistant solid-state polymer electrolytes include poly(vinylidene fluoride-co-hexafluoropropylene) P(VDF-HFP), sulfolane plasticizer, lithium salt, and ceramic nanoparticles with the basic formula Li7La3Zr2O12 (LLZO) and derivatives thereof. During the curing process, the presence of the LLZO nanoparticles prevent the P(VDF-HFP) from developing into a crystalline phase. In the electrolyte formed, the P(VDF-HFP) is in an amorphous phase with LLZO nanoparticles, lithium salt and sulfolane distributed in the polymer matrix. The solid-state electrolyte with the amorphous polymer phase exhibit higher ionic conductivities than those having a crystalline polymer phase. The LLZO contributes to mechanical properties of the electrolyte and also function as tough ceramic fillers that inhibit lithium dendrite growth during operation of lithium-ion cells and batteries. 5V all-solid-state lithium-ion batteries incorporated the electrolytes exhibit high energy densities (250-350 Whr/kg), high power densities (high discharge rate up to 5 C) and long service lives (500-1500 cycles, <2% irreversible loss/month). |
| FILED | Friday, September 09, 2022 |
| APPL NO | 17/942095 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/056 (20130101) Original (OR) Class H01M 10/0525 (20130101) H01M 10/0585 (20130101) H01M 50/414 (20210101) H01M 50/497 (20210101) H01M 2300/0071 (20130101) H01M 2300/0082 (20130101) H01M 2300/0091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230013103 | Urciuoli et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army DEVCOM, Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Damian P. Urciuoli (Bowie, Maryland); Erik S. Schroen (Pasadena, Maryland) |
| ABSTRACT | Novel electrically-isolated high-voltage sensors are provided which have low power dissipation. The sensors are formed of a circuit comprising first and second portions separated by an electrical isolation boundary with the first portion used for high-voltage, and the second portion for low-voltage. While they are decoupled electrically, they are coupled both optically and magnetically. The first portion comprises an LED which generates an optical signal corresponding to a high-voltage signal across the electrical-isolation boundary. The second portion comprises a photodiode which receives the optical signal emitted from the LED and outputs a corresponding low-voltage electrical signal. A temperature-compensating LED biasing sub-circuit may span both portions and include a temperature sensor, a coupled inductor magnetically coupling the electrical isolation boundary, and a rectifier and filter, to provide a bias to the LED which biases the LED to operate in a substantially-linear manner irrespective of the ambient temperature. |
| FILED | Wednesday, July 14, 2021 |
| APPL NO | 17/375394 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 15/22 (20130101) Original (OR) Class G01R 19/32 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 45/18 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230013620 | Walecka et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew C. Walecka (Tucson, Arizona); Andrew Thompson (Vail, Arizona) |
| ABSTRACT | A system and method uses field-oriented control (FOC) of a multi-phase motor to prevent thermal runaway of the thermal battery that powers the motor. An offset is applied to the flux command signal to ensure that the power level drawn from the thermal battery exceeds a minimum power level to avoid thermal runaway. This is done without any additional hardware, hence the reduced cost, inefficiencies and packaging volume of such hardware. In different modes, the offset is applied to prevent thermal runaway regardless of torque production, when the system is in failure and torque production is zero, for variable and intermittent periods when torque production is zero, and during normal operation to augment power drawn to produce torque. |
| FILED | Monday, July 19, 2021 |
| APPL NO | 17/379450 |
| CURRENT CPC | Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 21/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230013833 | CHATTOPADHYAY et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNIVERSITY OF CHICAGO (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ishanu CHATTOPADHYAY (Chicago, Illinois); Dmytro ONISHCHENKO (Chicago, Illinois); Yi HUANG (Chicago, Illinois) |
| ABSTRACT | A diagnosis prediction (DP) computing device (102) receives training datasets from a health records server (108A), an insurance claims server (108B), and other third party servers (108C). DP computing device builds a model based on the training datasets and stores the model on a database (106) via a database server (104). Using the model and a stochastic learning algorithm, a risk estimator (110) determines a prediction of a disease or disorder diagnosis of a patient to a client device (112). The prediction is based on data gathered pertaining to the patient including unprocessed raw data comprising records of diagnostic codes generated during past medical encounters from an insurance claims database. |
| FILED | Wednesday, September 23, 2020 |
| APPL NO | 17/763089 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 50/20 (20180101) Original (OR) Class G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230014134 | Jonker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Berend T. Jonker (Waldorf, Maryland); Connie H. Li (Alexandria, Virginia); Kathleen M. McCreary (Washington, District of Columbia); Olaf M.J. van 't Erve (Falls Church, Virginia) |
| ABSTRACT | Heterostructures include a layer of a two-dimensional material placed on a multiferroic layer. An ordered array of differing polarization domains in the multiferroic layer produces corresponding domains having differing properties in the two-dimensional material. When the multiferroic layer is ferroelectric, the ferroelectric polarization domains in the layer produce local electric fields that penetrate the two-dimensional material. The local electric fields modulate the charge carriers and carrier density on a nanometer length scale, resulting in the formation of lateral p-n or p-i-n junctions, and variations thereof appropriate for device functions. |
| FILED | Wednesday, September 28, 2022 |
| APPL NO | 17/955155 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4141 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/187 (20130101) H01L 21/02658 (20130101) H01L 29/66977 (20130101) Original (OR) Class H01L 29/78696 (20130101) H01L 33/002 (20130101) H01L 33/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230014296 | Katti |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Romney R. Katti (Shorewood, Minnesota) |
| ABSTRACT | An example device includes a magnetic device, a first magnetic shielding, and a second magnetic shielding. The magnetic device is configured to determine a perpendicular magnetization that extends along a z-axis. The first magnetic shielding comprises a first magnetic material, the first magnetic shielding extending at least partially between a first surface of the magnetic device and a second surface of the magnetic device in the z-axis. The first surface is on an opposite side of the magnetic device from the second surface of the magnetic device. The second magnetic shielding comprises a second magnetic material, the second magnetic shielding extending at least partially between a third surface of the magnetic device and a fourth surface of the magnetic device in an x-axis. The fourth surface is on an opposite side of the magnetic device from the third surface of the magnetic device. |
| FILED | Wednesday, July 14, 2021 |
| APPL NO | 17/305755 |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 41/34 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/552 (20130101) Original (OR) Class H01L 27/222 (20130101) H01L 43/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230014431 | Ross et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | First-Light USA, LLC (Seymour, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeremy B. Ross (Monticello, Illinois); Blake S. Good (Urbana, Illinois); Jacob A. Flagle (New Palestine, Indiana) |
| ABSTRACT | A frame having a clip for securing the frame to an article of clothing or other object. The frame includes a mount for receiving a removable module and a rotatably attached clip. The clip includes an opening for accommodating sewing ribs between portions of a webbing and a gate (which may be a locking wire) moveable between an open position and a closed position at one end of the opening. In the open position, the locking wire removably engages one of a pair of elongated members defining the opening, e.g., by removably engaging that elongated member at a recess in an outside edge thereof, and does not obstruct the opening. When in the closed position, the locking wire removably engages the other of the elongated members, for example by removably engaging that other elongated member at a recess in its outside edge, and obstructs the longitudinal opening. |
| FILED | Thursday, August 11, 2022 |
| APPL NO | 17/819270 |
| CURRENT CPC | Lighting Devices or Systems Thereof, Being Portable or Specially Adapted for Transportation F21L 4/027 (20130101) F21L 4/045 (20130101) Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for F21V 21/145 (20130101) F21V 21/0885 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses F21K, F21L, F21S and F21V, Relating to Uses or Applications of Lighting Devices or Systems F21W 2111/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230014436 | Sener et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexander Martin Sener (Cincinnati, Ohio); Brian David Keith (Cincinnati, Ohio); David Alan Frey (West Chester, Ohio); Jamil Darnell Grant (Maineville, Ohio) |
| ABSTRACT | A variable guide vane assembly is provided for a turbine defining a core air flowpath. The variable guide vane assembly includes an airfoil band defining a flowpath surface and a cavity. The variable guide vane assembly further includes an airfoil including a first end extending at least partially into the cavity of the airfoil band and an opposite second end, the airfoil extending generally along an axis between the first end and the second end and being moveable generally about the axis relative to the airfoil band. The variable guide vane assembly further includes a sealing element operable to form a seal between the first end of the airfoil and the airfoil band. |
| FILED | Wednesday, September 21, 2022 |
| APPL NO | 17/949601 |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/042 (20130101) F01D 11/003 (20130101) F01D 11/005 (20130101) Original (OR) Class F01D 17/162 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) F02C 9/22 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2220/3213 (20130101) F05D 2240/35 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230015160 | McFaddin |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Donald A. McFaddin (Williams, Indiana) |
| ABSTRACT | Provided is a Fall Arrest Staple that includes a slanted base with a flat welding surface and an integral ring section extending from the base that is constructed from aluminum with a maximum internal radii that is capable of accepting a small carabineer. The staple can be welded to an aluminum pole, such as a 4″OD×0.25″ mast that is found on a ship. Advantages provided by the staple include the ability of welding in a perpendicular orientation to a ship deck (in the direction of a fall), welding to a curved aluminum backing plate, and the use of the staple with a curved backing plate that can be welded directly to a ship mast. |
| FILED | Thursday, June 30, 2022 |
| APPL NO | 17/854502 |
| CURRENT CPC | Devices, Apparatus or Methods for Life-saving A62B 35/0068 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230015266 | BROWN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ashley C. BROWN (Raleigh, North Carolina); Kimberly A. NELLENBACH (Raleigh, North Carolina) |
| ABSTRACT | Disclosed are methods of promoting wound healing in a patient in need thereof comprising administering to the patient a composition comprising a neonatal fibrin scaffold. Further disclosed are in vitro methods for evaluating a target composition on human wound healing comprising a neonatal porcine plasma scaffold with the target composition and evaluating scaffold properties of the plasma sample. |
| FILED | Monday, November 30, 2020 |
| APPL NO | 17/780843 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/54 (20130101) A61L 27/225 (20130101) Original (OR) Class A61L 27/227 (20130101) A61L 2300/41 (20130101) A61L 2300/402 (20130101) A61L 2300/404 (20130101) A61L 2400/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230015346 | Dunn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Combat Capabilities Development Command, Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ryan M. Dunn (Belcamp, Maryland); Kevin R. Hart (Milwaukee, Wisconsin); Eric D. Wetzel (Bel Air, Maryland) |
| ABSTRACT | A polymer body includes a first thermoplastic polymer, and a second thermoplastic polymer. The first thermoplastic polymer and the second thermoplastic polymer form a continuous solid structure. The first thermoplastic polymer forms an external supporting structure that at least partially envelops the second thermoplastic polymer. A first flow temperature of the first thermoplastic polymer is at least 10° C. higher than a second flow temperature of the second thermoplastic polymer. The first thermoplastic polymer may be removable by exposure to a selective solvent. |
| FILED | Thursday, September 15, 2022 |
| APPL NO | 17/945369 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 35/02 (20130101) B29C 48/16 (20190201) B29C 48/91 (20190201) B29C 55/00 (20130101) B29C 64/106 (20170801) B29C 64/118 (20170801) B29C 71/0009 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 70/00 (20141201) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/24 (20130101) D01D 5/30 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 8/00 (20130101) D01F 8/10 (20130101) D01F 8/14 (20130101) Original (OR) Class D01F 8/18 (20130101) Optical Elements, Systems, or Apparatus G02B 6/02033 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230015863 | Lontz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HDT EXPEDITIONARY SYSTEMS, INC. (Solon, Ohio) |
| ASSIGNEE(S) | HDT EXPEDITIONARY SYSTEMS, INC. (Solon, Ohio) |
| INVENTOR(S) | Travis Lontz (Fredericksburg, Virginia); Charles Deighton (Milford, Ohio); Wade Milek (Mason, Ohio) |
| ABSTRACT | A portable shelter with electromagnetic interference (EMI) protection includes a plurality of walls that define an interior space. The walls can be fixed or movable. An EMI protected edge connector joins at least two of the walls together. The EMI protected edge connector assembly can be fixed or hinged. The edge connector can include a metallic outer edge member with two legs and a separate metallic inner edge member with two legs to define an edge channel therebetween with: (i) the first outer leg and the first inner leg are arranged parallel and spaced-apart relative to each other; and (ii) the second outer leg and the second inner leg arranged parallel and spaced-apart relative to each other. The shelter walls can include an inner surface covered by a metallic foil inner layer. A first wall panel is received in a first portion of the edge channel with its metallic foil inner layer contacting the inner edge member and a second wall panel is received in a second portion of the edge channel with it metallic foil inner layer contacting the inner edge member. |
| FILED | Thursday, July 14, 2022 |
| APPL NO | 17/864618 |
| CURRENT CPC | General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/92 (20130101) E04B 1/3445 (20130101) E04B 1/34336 (20130101) E04B 1/34384 (20130101) E04B 2001/925 (20130101) E04B 2103/06 (20130101) Structural Elements; Building Materials E04C 2/292 (20130101) E04C 2/526 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 9/0001 (20130101) Original (OR) Class H05K 9/0081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230015952 | Kosyakov |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alexander Kosyakov (Albany, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexander Kosyakov (Albany, New York) |
| ABSTRACT | A composite solid electrolyte comprises a first component comprising an aluminosilicate-based ceramic and a second component comprising a non-conductive polymer. |
| FILED | Monday, May 16, 2022 |
| APPL NO | 17/745763 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0562 (20130101) Original (OR) Class H01M 2300/0068 (20130101) H01M 2300/0082 (20130101) H01M 2300/0091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230016120 | Montoya et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Naval Information Warfare Center Pacific (San Diego, California) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (San Diego, California) |
| INVENTOR(S) | Sergio A. Montoya (Chula Vista, California); Benjamin J. Taylor (Escondido, California); Susan Anne Elizabeth Berggren (San Diego, California); Anna Leese de Escobar (Encinitas, California); Nicholas Ferrante (Lakeside, California) |
| ABSTRACT | A superconducting electronic circuit includes at least two SQUID elements, an array of at least three Josephson Junctions, and a magnetic source element. Each SQUID element has no shared Josephson Junctions or at least one shared Josephson Junction with another SQUID element and at least one exclusive Josephson Junction. The array of at least three Josephson Junctions are connected in one, two, or three-dimensions. The magnetic source element has an electrically-tunable spatially non-uniform magnetic field. |
| FILED | Wednesday, July 14, 2021 |
| APPL NO | 17/375118 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/0354 (20130101) Original (OR) Class Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 6/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230016456 | Chinnaiyan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Arul Chinnaiyan (Plymouth, Michigan); John Prensner (Ann Arbor, Michigan); Matthew Iyer (Ann Arbor, Michigan) |
| ABSTRACT | The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to ncRNAs as diagnostic markers and clinical targets for prostate, lung, breast and pancreatic cancer. |
| FILED | Monday, July 18, 2022 |
| APPL NO | 17/813193 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230017484 | KIMURA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Adam KIMURA (Lewis Center, Ohio); James SCHAFFRANEK (Westerville, Ohio); Alexander MANG (Columbus, Ohio) |
| ABSTRACT | The present disclosure provides a circuit design validation system. In one embodiment, the system includes polygon extraction circuitry to determine, based on layer images of a fabricated integrated circuit (IC), a plurality of polygons associated with a layer of the fabricated IC; and cell pattern matching circuitry to search the polygons defined within a layer image of the fabricated IC to determine a match between a cell template of a standard cell library and the plurality of polygons defined within the layer image of the fabricated IC. |
| FILED | Thursday, June 30, 2022 |
| APPL NO | 17/854029 |
| CURRENT CPC | Electric Digital Data Processing G06F 30/392 (20200101) G06F 30/398 (20200101) Original (OR) Class G06F 2111/20 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230017608 | Evans et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Aspen Aerogels, Inc. (Northborough, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Owen Richard Evans (Chelmsford, Massachusetts); Nicholas Anthony Zafiropoulos (Wayland, Massachusetts); Shannon Olga White (Bolton, Massachusetts); Wenting Dong (Marlborough, Massachusetts); Wendell E. Rhine (Belmont, Massachusetts) |
| ABSTRACT | The present invention provides a fiber-reinforced aerogel material which can be used as insulation in thermal battery applications. The fiber-reinforced aerogel material is highly durable, flexible, and has a thermal performance that exceeds the insulation materials currently used in thermal battery applications. The fiber-reinforced aerogel insulation material can be as thin as 1 mm less, and can have a thickness variation as low as 2% or less. Also provided is a method for improving the performance of a thermal battery by incorporating a reinforced aerogel material into the thermal battery. Further provided is a casting method for producing thin fiber-reinforced aerogel materials. |
| FILED | Friday, May 06, 2022 |
| APPL NO | 17/738852 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/0091 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 6/36 (20130101) H01M 6/5072 (20130101) H01M 50/116 (20210101) H01M 50/138 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230017695 | Phillip et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Ryan E. Phillip (Covington, Louisiana); Allison M. Penko (Diamondhead, Mississippi) |
| ABSTRACT | A method of training a machine learning model to predict seafloor ripple geometry that includes receiving one or more input values, each input value based on an observation associated with ocean wave and seafloor conditions, and preprocessing the one or more input values. The method includes generating a training data set based on the preprocessed data set, splitting the training data set into a plurality of folds, and training via stacked generalization the machine learning model by performing a cross validation of each fold of training data based on at least one deterministic equilibrium ripple predictor model and on at least one machine learning algorithm. The method may include generating via the trained machine learning model, a set of one or more seafloor ripple geometry predictions, and performing Bayesian regression on the set of one or more seafloor ripple predictions to generate a probabilistic distribution of predicted seafloor ripple geometry. |
| FILED | Tuesday, June 28, 2022 |
| APPL NO | 17/851390 |
| CURRENT CPC | Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 99/005 (20130101) Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) Original (OR) Class G06N 20/20 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230018537 | Brandsma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| ASSIGNEE(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| INVENTOR(S) | Joost Brandsma (Bethesda, Maryland); Danielle Clark (Bethesda, Maryland); Rittal Mehta (Bethesda, Maryland); Deborah Striegel (Bethesda, Maryland) |
| ABSTRACT | The present disclosure describes methods and systems for predicting severe disease in an individual with sepsis or at risk of developing sepsis, in order to prevent severe disease in an individual with sepsis. The present disclosure also describes methods of using topological data analysis and/or clustering to stratify sepsis based on biomolecular signatures and identify distinct phenotypes in sepsis patients. |
| FILED | Thursday, December 24, 2020 |
| APPL NO | 17/757984 |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) G16B 40/20 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/30 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230018592 | Welle |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | US Government by the Secretary of the Air Force (Wright Patterson AFB, Ohio) |
| ASSIGNEE(S) | US Government by the Secretary of the Air Force (Wright Patterson AFB, Ohio) |
| INVENTOR(S) | Eric Welle (Niceville, Florida) |
| ABSTRACT | A shaped lens for minimizing differences in time of arrival at the output surface of an explosive assembly. The lens is plano-convex with the convex shape oriented towards the explosive charge. The lens becomes monotonically thicker as the center of the lens is radially approached from the edge, according to a formula accounting for the detonation velocity of the explosve and velocity of the shockwave through the lens. The lens is preferably incorporated into a test fixture using a liquid explosive, such as nitromethane. The test fixture may be assembed on site, at the test location. |
| FILED | Friday, July 09, 2021 |
| APPL NO | 17/305589 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/227 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230018759 | Mirkin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chad A. Mirkin (Whilmette, Illinois); Jingshan Du (Evanston, Illinois); Donghoon Shin (Evanston, Illinois); Vinayak P. Dravid (Evanston, Illinois) |
| ABSTRACT | A method of forming a halide perovskite nanocrystal array having a plurality of halide perovskite nanocrystals arranged in a pattern can include coating an array of pens with a first ink comprising at least one first perovskite precursor having the formula AX and at least one second perovskite precursor having the formula BX′2 dissolved in a solvent. A is a cation, B is a metal, and X and X′ are each a halogen. The method further includes contacting a substrate with the coated pen array to thereby deposit the first ink indias a pattern of printed indicia on the substrate. The printed indicia form nanoreactors on the substrate and a halide perovskite nanocrystal nucleates and grows within each nanoreactor to form the halide perovskite nanocrystal array. |
| FILED | Friday, December 04, 2020 |
| APPL NO | 17/782613 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 21/16 (20130101) Original (OR) Class Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/322 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230018837 | LAVIK et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Erin LAVIK (Ellicott City, Maryland); Nuzhat MAISHA (Halethorpe, Maryland) |
| ABSTRACT | One of the significant challenges to translation of intravenously administered nanomaterials has been complement-mediated infusion reactions which can be lethal. Slow infusions can reduce infusion reactions, but slow infusions are not always possible in applications like controlling bleeding following trauma. Nanocapsules based on polyurethane are introduced as candidates that do not substantially activate complement protein C5a and the PEGylation and functionalization of the nanocapsules with the GRGDS peptide to create a new class of hemostatic nanomaterials is disclosed. Advantageously, the nanocapsules substantially avoid complement-mediated infusion reactions, promote faster clotting than controls, maintain maximum clot firmness, and do not activate pro-inflammatory cytokines. |
| FILED | Friday, July 15, 2022 |
| APPL NO | 17/812746 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/19 (20130101) A61K 9/5146 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
20230018859 — ELECTROCHEMICAL SENSORS FOR ANALYTE DETECTION IN WATER AND REFERENCE CORRECTION METHOD
| US 20230018859 | Fury et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brewer Science, Inc. (Rolla, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan J. Fury (Springfield, Missouri); Xi Cao (Tracy, California); Austin Peters (Springfield, Missouri); Chad Lakin (Springfield, Missouri); Cody Simmons (Springfield, Missouri); Alec Neeson (Springfield, Missouri) |
| ABSTRACT | A sensing platform for continuous water resource monitoring by electrochemical detection and solution parameter correction is provided. The sensing platform employs a solid-state electrolyte three-electrode cell, creating a high ionic strength environment within the solid-state electrolyte membrane, which is in ion exchange equilibria with the sampled solution. This device may be used as a standalone sensor in environments where the water parameters (pH temperature, and ionic strength) are controlled, or in concert with compensation sensors where water parameters are not controlled. |
| FILED | Friday, July 01, 2022 |
| APPL NO | 17/856816 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/38 (20130101) Original (OR) Class G01N 27/3335 (20130101) G01N 27/4161 (20130101) G01N 33/182 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230018948 | Ding et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yuzhen Ding (Tempe, Arizona); Nupur Thakur (Tempe, Arizona); Baoxin Li (Chandler, Arizona) |
| ABSTRACT | Described herein are means for integrating a defense mechanism into deep-learning-based systems to defend against adversarial attacks. For instance, an exemplary system is specially configured for adding a convolutinal defense layer to a neural network containing orthogonal kernels. Such a system generates the convolutional defense layer based on generating a set of learned kernals to increase diversity of network architecture, in which generating the set of learned kernals includes feeding an output of the convolutional defense layer into the neural network, further in which generating the convolutional defense layer includes selecting one or more orthogonal kernals, duplicating as needed and arranging them in a particular order. Such an embodiment further includes training the neural network with the added convolutional defense layer based on the increased diversity of network architecture; and defending against adverse attacks via constraining the effect of adversarial data generated by the adversarial attacks. |
| FILED | Tuesday, April 26, 2022 |
| APPL NO | 17/730051 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/55 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/063 (20130101) G06N 20/10 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230019027 | Bazan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents Of The University Of California (Oakland, California); Nanyang Technological University (Singapore, Singapore); National University of Singapore (Singapore, Singapore) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Guillermo Carlos Bazan (Santa Barbara, California); Hengjing Yan (Goleta, California); Jamie Hinks (Singapore, Singapore); Elias L. Bazan (Placentia, California); Chenyao Nie (Goleta, California); Jennifer Moon (Placentia, California) |
| ABSTRACT | Disclosed herein are combinations that include one or more conjugated oligoelectrolyte compounds, or pharmaceutically acceptable salts, hydrates, or solvates thereof, and one or more antibiotics. Combination of one or more conjugated oligoelectrolyte compounds and one or more antibiotics can potentiate the activity of the one or more antibiotics. Also disclosed are methods treating, reducing the severity of and/or slowing the progression of a bacterial infection, such as Gram-positive and Gram-negative bacteria, using a combination described herein. |
| FILED | Thursday, November 12, 2020 |
| APPL NO | 17/755967 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/14 (20130101) Original (OR) Class A61K 31/43 (20130101) A61K 31/155 (20130101) A61K 31/165 (20130101) A61K 31/444 (20130101) A61K 31/496 (20130101) A61K 31/635 (20130101) A61K 31/4545 (20130101) A61K 31/4995 (20130101) A61K 38/12 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230019342 | Heath et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James R. Heath (Pasadena, California); Arundhati Nag (Pasadena, California); Samir Das (Pasadena, California); Joseph O. Varghese (Pasadena, California); Ryan K. Henning (Pasadena, California) |
| ABSTRACT | The present application provides stable peptide-based Akt capture agents and methods of use as detection and diagnosis agents and in the treatment of diseases and disorders. The application further provides methods of manufacturing Akt capture agents using iterative on-bead in situ click chemistry. |
| FILED | Monday, June 27, 2022 |
| APPL NO | 17/850743 |
| CURRENT CPC | Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/582 (20130101) G01N 33/5748 (20130101) Original (OR) Class G01N 2333/91205 (20130101) G01N 2440/14 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230019589 | Dawson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Naval Information Warfare Center Pacific (San Diego, California) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (San Diego, California) |
| INVENTOR(S) | David Carlos Dawson (Lemon Grove, California); Ricardo Santoyo-Mejia (Chula Vista, California); Ronald B. Thompson (San Diego, California); Jaime E. Radulovich (San Diego, California) |
| ABSTRACT | An electronically steerable parasitic array (ESPAR) antenna system that includes an ESPAR antenna, a GPS receiver, a GPS low-noise amplifier, a power detector module, and a central processing unit. The GPS receiver is connected to the ESPAR antenna as a separate component. The GPS low-noise amplifier strengthens a signal to propagate through the transmission line and operates in the L1 and L2 GPS bands. The power detector module provides additional amplification for noise quantification. The power detector receives an RF power level and converts the RF power level into a DC voltage output. The central processing unit includes memory that is capable of storing the DC voltage output from the power detector. |
| FILED | Wednesday, July 14, 2021 |
| APPL NO | 17/375804 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/21 (20130101) Antennas, i.e Radio Aerials H01Q 3/34 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230019900 | Bradley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Henry M. Jackson Foundation for the Advancement of Military Medicine (Bethesda, Maryland); The Government of the United States, as represented by the Secretary of the Army (Fort Detrick, Maryland); The United States of America, as Represented by the Secretary of the Navy (Silver Spring, Maryland) |
| ASSIGNEE(S) | Henry M. Jackson Foundation for the Advancement of Military Medicine (Bethesda, Maryland); The Government of the United States, as represented by the Secretary of the Army (Fort Detrick,, Maryland); The United States of America, as Represented by the Secretary of the Navy (Silver Spring, Maryland) |
| INVENTOR(S) | Matthew J. Bradley (Silver Spring, Maryland); Eric A Elster (Kensington, Maryland); Vivek Khatri (Bethesda, Maryland); John S Oh (Fort Detrick, Maryland); Seth A Schobel (Clarksburg, Maryland) |
| ABSTRACT | The present disclosure describes methods and systems for predicting if a subject has an increased risk of having or developing venous thromboembolism, including prior to the detection of symptoms thereof and/or prior to onset of any detectable symptoms thereof. The present disclosure also describes a method of generating a model for predicting venous thromboembolism. |
| FILED | Thursday, December 03, 2020 |
| APPL NO | 17/756805 |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 40/00 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230019931 | Brewer |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tony Brewer (Plano, Texas) |
| ABSTRACT | Disclosed in some examples are methods, systems, memory controllers, devices, and machine-readable mediums which minimize this stall time by returning a memory write acknowledgement once a write command has been selected by the memory controller input multiplexor rather than when the memory write command has been performed. Because the memory controller enforces an ordering to memory once the packet has been selected at an input multiplexor, ordering of prior and subsequent requests to the same address location are preserved and providing the response early allows the processor to continue its operations earlier without any harmful effects. |
| FILED | Monday, September 26, 2022 |
| APPL NO | 17/952971 |
| CURRENT CPC | Electric Digital Data Processing G06F 13/161 (20130101) G06F 13/287 (20130101) G06F 13/1642 (20130101) G06F 13/1689 (20130101) Original (OR) Class G06F 15/7825 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230019995 | Locasto et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Locasto (Lebanon, New Jersey); Bruce DeBruhl (Arroyo Grande, California); Ulf Lindqvist (San Luis Obispo, California); David Stoker (Menlo Park, California); Ioannis Agadakos (Chicago, Illinois) |
| ABSTRACT | A method may involve applying, by a testing computing device, a distortion to a computing device under test. The distortion includes operating the computing device under test at a performance range of a computational resource that could cause the computing device under test to operate outside a normal range. The method may also involve receiving, by the testing computing device and in response to the applying of the distortion, one or more digital signals from the computing device under test. The method may further involve comparing, by the testing computing device, the one or more digital signals to one or more baseline digital signals associated with the computing device under test. The method may also involve detecting, based on the comparing, a presence of at least one anomalous element that could be indicative of a hostile element in the computing device under test. |
| FILED | Friday, July 15, 2022 |
| APPL NO | 17/866243 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/31703 (20130101) G01R 31/31917 (20130101) Electric Digital Data Processing G06F 21/566 (20130101) Original (OR) Class G06F 2221/034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230020178 | Clerk et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aashish Clerk (Chicago, Illinois); Alexander McDonald (Chicago, Illinois) |
| ABSTRACT | Optimally detuned parametric amplification amplifies a signal in a resonator that is driven off-resonance, with respect to a signal mode, using a far-detuned pump. This pump establishes a parametric drive strength, and is “far-detuned” in that its detuning from the signal mode is greater than the drive strength. The amplitude and frequency of the pump are chosen so that the eigenfrequency of the resulting Bogoliobov mode matches a photonic loss rate of the Bogoliobov mode. In this case, a signal coupled into the Bogoliobov mode will be amplified with a gain that is broader and flatter than that achieved with conventional parametric amplification, and is not limited by a gain-bandwidth product. Optimally detuned parametric amplification may be used for degenerate or non-degenerate parametric amplification, and may be used to amplify microwaves, light, electronic signals, acoustic waves, or any other type of signal that can be amplified using conventional parametric amplification. |
| FILED | Sunday, December 13, 2020 |
| APPL NO | 17/756481 |
| CURRENT CPC | Amplifiers H03F 3/189 (20130101) H03F 7/04 (20130101) Original (OR) Class H03F 19/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230020773 | Resh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Apptronik, Inc. (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bradley Aaron Resh (Austin, Texas); Michael Sanford Boudreaux (Cedar Park, Texas); Daniel Stephen Mitchell (Dripping Springs, Texas); Joshua Alexander James (Leander, Texas); Steven David Riddle (Tampa, Florida); Orion Hubert Campbell, IV (Austin, Texas); Jonas Alexan Fox (Austin, Texas); Nicholas Arden Paine (Austin, Texas) |
| ABSTRACT | A robotic arm system comprising a deployment system or a base, a first joint, and a manipulator coupled to the deployment system or base at the first joint and movable relative to the deployment link or base about the first joint. The manipulator includes a manipulator link, a second joint coupled to the manipulator link distal from the first joint, an elevation linkage coupled to the manipulator link at the second joint, a wrist coupled to the elevation linkage distal from the second joint, and an end effector coupled to the wrist. The end effector can change elevation via the elevation link without changing orientation. |
| FILED | Thursday, April 28, 2022 |
| APPL NO | 17/732282 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/0027 (20130101) Original (OR) Class B25J 9/106 (20130101) B25J 15/0052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230020829 | BRISSON et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John G. BRISSON (Rockport, Massachusetts); Kyle J. THOMPSON (Lynnfield, Massachusetts); John CUMMINGS (Stoneham, Massachusetts); Jacob Lazer ADAMS (McLean, Virginia); Lauren CANTLEY (Cambridge, Massachusetts) |
| ABSTRACT | Drawn polymer fibers have internal channels running, at least partially, through the length of the fibers. These fibers may be configured to for use as thermal isolators that can thermally isolate material at the central core of the fiber from the outside environment. In such instances, the channels may be used as insulating channels and/or a heating or cooling fluid can be pumped through the channels to maintain the temperature of the material at the inner core. As another application, the fibers may be used as recuperative, regenerative, parallel-flow, counter-flow, cross-flow or condenser/evaporator heat exchangers. In this case, the channels may be used to direct fluid flow. The fiber may allow for the exchange of heat between fluids in the channels. |
| FILED | Wednesday, July 14, 2021 |
| APPL NO | 17/375182 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 55/22 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/18 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 1/022 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20230013531 | LEE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York) |
| ASSIGNEE(S) | RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York) |
| INVENTOR(S) | Sangwoo LEE (Cohoes, New York); Chulsung BAE (Cohoes, New York); Carrie Lynn TRANT (Troy, New York) |
| ABSTRACT | An anion exchange membrane is composed of a copolymer of 1,1-diphenylethylene and one or more styrene monomers, such as 4-tert-butylstyrene. The copolymer includes a backbone substituted with a plurality of ionic groups coupled to phenyl groups on the backbone via hydrocarbyl tethers between about 1 and about 7 carbons in length. High-temperature conditions enabled by these copolymers enhance conductivity performance, making them particularly suitable for use in anion exchange membranes in fuel cells, electrolyzers employing hydrogen, ion separations, etc. The properties of the membranes can be tuned via the degree of functionalization of the phenyl groups and selection of the functional groups, such as quaternary ammonium groups. Several processes can be used to incorporate the desired ionic functional groups into the polymers, such as chloromethylation, radical bromination, Friedel-Crafts acylation and alkylation, sulfonation followed by amination, or combinations thereof. |
| FILED | Friday, September 02, 2022 |
| APPL NO | 17/901985 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 41/14 (20130101) Original (OR) Class Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 212/08 (20130101) C08F 212/32 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/2231 (20130101) C08J 2325/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230014161 | Berry et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John Berry (Madison, Wisconsin); Christian Wallen (Madison, Wisconsin); Michael Trenerry (Madison, Wisconsin); Tristan Brown (Houston, Texas); Sungho Park (Madison, Wisconsin) |
| ABSTRACT | Methods and catalysts for oxidizing ammonia to nitrogen are described. Specifically, diruthenium complexes that spontaneously catalyze this reaction are disclosed. Accordingly, the disclosed methods and catalysts can be used in various electrochemical cell-based energy storage and energy production applications that could form the basis for a potential nitrogen economy. |
| FILED | Wednesday, September 07, 2022 |
| APPL NO | 17/939405 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/1815 (20130101) Original (OR) Class B01J 2231/70 (20130101) B01J 2531/821 (20130101) Non-metallic Elements; Compounds Thereof; C01B 21/02 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/01 (20210101) C25B 11/085 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230014285 | Kante et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (OAKLAND, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Boubacar Kante (Orinda, California); Abdoulaye Ndao (El Cerrito, California); Li-Yi Hsu (El Cerrito, California); Jeongho Ha (Richmond, California) |
| ABSTRACT | An octave bandwidth, achromatic metalens configured to operate in light wavelengths having a range of approximately 640 nm to 1200 nm. |
| FILED | Monday, November 23, 2020 |
| APPL NO | 17/779727 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) Original (OR) Class G02B 3/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230015489 | Rueger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zachariah Rueger (Overland Park, Kansas); Amer Sadikovic (Ballwin, Missouri) |
| ABSTRACT | A lattice structure and system for absorbing energy, damping vibration, and reducing shock. The lattice structure comprises a plurality of unit cells, each unit cell comprising a plurality of rib elements with at least a portion of the rib elements including a solid bendable hinge portion for converting energy into linear motion along a longitudinal axis of the respective rib element. |
| FILED | Tuesday, July 13, 2021 |
| APPL NO | 17/374402 |
| CURRENT CPC | Springs; Shock-absorbers; Means for Damping Vibration F16F 3/023 (20130101) Original (OR) Class F16F 15/073 (20130101) F16F 2224/0208 (20130101) F16F 2230/34 (20130101) F16F 2238/022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20230015505 — MODULAR, CELL-FREE PROTEIN EXPRESSION VECTORS TO ACCELERATE BIOLOGICAL DESIGN IN CELLS
| US 20230015505 | JEWETT et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois); LanzaTech, Inc. (Skokie, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois); LanzaTech, Inc. (Skokie, Illinois) |
| INVENTOR(S) | Michael C. JEWETT (Evanston, Illinois); Ashty S. KARIM (Chicago, Illinois); Michael KOEPKE (Skokie, Illinois); Darmawi JUMINAGA (Highland Park, Illinois); Fungmin LIEW (Skokie, Illinois) |
| ABSTRACT | Disclosed are compositions, methods, and kits for performing cell-free protein synthesis (CFPS) and for expressing proteins in cells. Particularly disclosed are vectors comprising Golden Gate sites for cloning, methods for preparing such vectors, and the use thereof for performing CFPS and for expressing proteins in cells such as in naturally occurring or recombinant species of Clostridia, including Clostridium autoethanogenum. |
| FILED | Thursday, December 03, 2020 |
| APPL NO | 17/782123 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 15/66 (20130101) C12N 15/74 (20130101) Original (OR) Class C12N 2330/51 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230016029 | O'Brien et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert C. O'Brien (Idaho Falls, Idaho); Owen O. Abe (Baltimore, Maryland) |
| ABSTRACT | Methods and systems for producing feedstock powders, suitable for use in laser-based additive manufacturing, use laser ablation to vaporize a source material, which may be in bulk solid or solid coarse grain form. The source material is vaporized by a laser (or other focused energy source) in a vaporization chamber that is temperature controlled to provide a vertical thermal gradient. The vertical thermal gradient may be controlled to, in turn, control the nucleation, coagulation, and agglomeration of the vaporized molecules, enabling formation of microparticles that may then be used as feedstock powders in laser-based additive manufacturing. The produced feedstock powder particles may be of uniform composition, of uniform shape (e.g., substantially spherical), and of uniform phase or homogeneously-mixed phases. |
| FILED | Tuesday, December 22, 2020 |
| APPL NO | 17/757937 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 9/12 (20130101) Original (OR) Class Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/36 (20130101) B23K 26/127 (20130101) B23K 2103/08 (20180801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 40/10 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230016315 | Tripathy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Prabhat K. Tripathy (Idaho Falls, Idaho); Michael R. Shaltry (Idaho Falls, Idaho) |
| ABSTRACT | An electrochemical cell comprising an anode, an electrolyte adjacent to the anode, a cathode adjacent to the electrolyte, and an interconnector adjacent to the cathode. One or more of the anode, the cathode, and the interconnector comprises a ternary oxide material comprising the chemical formula of M1xM2yOz, where M1 is an alkali metal element or an alkaline earth metal element, M2 is a platinum group metal, each of x and y is independently an integer less than or equal to 2, and z is independently an integer less than or equal to 4. A system comprising one or more electrochemical cells and methods of forming the ternary oxide material are also disclosed. |
| FILED | Wednesday, July 13, 2022 |
| APPL NO | 17/812413 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/14 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/9033 (20130101) Original (OR) Class H01M 2008/1293 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230016731 | O'Malley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ronan O'Malley (Oakland, California); Leo Baumgart (Oakland, California) |
| ABSTRACT | Described herein are affinity-labeled polypeptide compositions, such as affinity-labeled transcription factor compositions, and methods of using such compositions to evaluate interactions of the polypeptide with other molecules such as nucleic acids. |
| FILED | Monday, May 23, 2022 |
| APPL NO | 17/750844 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1006 (20130101) C12N 15/1065 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6855 (20130101) C12Q 1/6874 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230017076 | HITCHCOCK et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SAVANNAH RIVER NUCLEAR SOLUTIONS, LLC (Aiken, South Carolina); CLEMSON UNIVERSITY RESEARCH FOUNDATION (Clemson, South Carolina); GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | DALE A. HITCHCOCK (AIKEN, South Carolina); STEVEN M. SERKIZ (AIKEN, South Carolina); TIMOTHY M. KRENTZ (AIKEN, South Carolina); JOSEF A. VELTEN (DALLAS, Texas); KYLE S. BRINKMAN (CLEMSON, South Carolina); ERIC M. VOLGEL (MARIETTA, Georgia); KATHERINE T. YOUNG (ATLANTA, Georgia) |
| ABSTRACT | Methods and systems for the separation of hydrogen isotopes from one another are described. Methods include utilization of a hydrogen isotope selective separation membrane that includes a hydrogen isotope selective layer (e.g., graphene) and a hydrogen ion conductive supporting layer. An electronic driving force encourages passage of isotopes selectively across the membrane at an elevated separation temperature to enrich the product in a selected hydrogen isotope. |
| FILED | Friday, July 29, 2022 |
| APPL NO | 17/877167 |
| CURRENT CPC | Separation B01D 59/14 (20130101) B01D 59/42 (20130101) Original (OR) Class B01D 71/02 (20130101) B01D 71/021 (20130101) B01D 71/022 (20130101) B01D 71/024 (20130101) B01D 71/025 (20130101) B01D 71/027 (20130101) Non-metallic Elements; Compounds Thereof; C01B 4/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230017556 | Azenkeng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Energy and Environmental Research Center Foundation (Grand Forks, North Dakota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexander Azenkeng (Grand Forks, North Dakota); Jason Laumb (Grand Forks, North Dakota) |
| ABSTRACT | A method of forming graphite includes carbonizing an upgraded coal, to form a carbonized upgraded coal. The method also includes graphitizing the carbonized upgraded coal, to form the graphite. |
| FILED | Tuesday, September 13, 2022 |
| APPL NO | 17/931720 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/205 (20170801) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/82 (20130101) C01P 2004/03 (20130101) C01P 2004/30 (20130101) C01P 2006/40 (20130101) C01P 2006/80 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/587 (20130101) H01M 10/0525 (20130101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230017642 | Dai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Apple Inc. (Cupertino, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hongli Dai (Los Altos, California); Jongho Jeon (San Jose, California); Libo Hu (Mountain View, California); Paul M. Bayley (Santa Clara, California); Khalil Amine (Oak Brook, Illinois); Mingfu He (Palos Park, Illinois); Qian Liu (Darien, Illinois); Zhengcheng Zhang (Naperville, Illinois) |
| ABSTRACT | This disclosure relates generally to battery cells, and more particularly, electrolyte additives for use in lithium ion battery cells. |
| FILED | Wednesday, June 08, 2022 |
| APPL NO | 17/835766 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/0404 (20130101) H01M 10/46 (20130101) H01M 10/0567 (20130101) Original (OR) Class H01M 10/0568 (20130101) H01M 10/0569 (20130101) H01M 2300/0042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230017721 | MUKERJEE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sanjeev MUKERJEE (Mansfield, Massachusetts); Robert ALLEN (deceased) (Peabody, Massachusetts); Huong Thi Thanh DOAN (Worcester, Massachusetts); Ian KENDRICK (Somerville, Massachusetts) |
| ABSTRACT | Functionalized catalysts for use in a hydrogen evolution reaction (HER) contain nanoparticles containing a transition metal enveloped in layers of graphene, which renders the nanoparticles resistant to passivation while maintaining an optimal ratio of transition metal and transition metal oxide in the nanoparticles. The catalysts can be utilized with anionic exchange polymer membranes for hydrogen production by alkaline water electrolysis. |
| FILED | Monday, December 21, 2020 |
| APPL NO | 17/783886 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/18 (20130101) B01J 23/755 (20130101) Original (OR) Class B01J 35/0013 (20130101) B01J 35/1028 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/0656 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230017923 | FREIDERICH et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John W. FREIDERICH (Oak Ridge, Tennessee); Tasha L. BOYD (Clinton, Tennessee) |
| ABSTRACT | Methods for electropolishing and coating aluminum on a surface of an air and/or moisture sensitive substrate, including: in a vessel, submerging the substrate in a first molten salt bath and applying an anodizing current to the substrate at a first temperature to electropolish the surface of the substrate; wherein the first molten salt bath includes one of a first organic salt bath and first inorganic salt bath; wherein, when used, the first organic salt bath includes one of (a) aluminum halide and ionic liquid, (b) a combination of an aluminum halide and halogenatedmethylphenylsulfone (C6(H5-y, Xy)SO2CX3, where y is a number from 0-5), (c) a combination of an aluminum halide, an ionic liquid, and halogenatedmethylphenylsulfone (C6(H5-y, Xy)SO2CX3), and (d) AlF3-organofluoride-hydrofluoric acid adduct; wherein, when used, the first inorganic salt bath includes aluminum halide and alkali metal halide; and wherein the anodizing current is 10-30 mA/cm2. |
| FILED | Thursday, August 25, 2022 |
| APPL NO | 17/895148 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 18/31 (20130101) C23C 18/1848 (20130101) Original (OR) Class Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 3/44 (20130101) C25D 3/665 (20130101) Processes for the Electrolytic Removal of Materials From Objects; Apparatus Therefor C25F 3/16 (20130101) C25F 3/22 (20130101) C25F 3/26 (20130101) C25F 3/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230018217 | Dai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Apple Inc. (Cupertino, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hongli Dai (Los Altos, California); Jongho Jeon (San Jose, California); Libo Hu (Mountain View, California); Paul M. Bayley (Santa Clara, California); Khalil Amine (Oak Brook, Illinois); Mingfu He (Palos Park, Illinois); Qian Liu (Darien, Illinois); Zhengcheng Zhang (Naperville, Illinois) |
| ABSTRACT | This disclosure relates generally to battery cells, and more particularly, electrolyte additives for use in lithium ion battery cells. |
| FILED | Wednesday, June 08, 2022 |
| APPL NO | 17/835772 |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/02 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/0404 (20130101) H01M 10/0567 (20130101) Original (OR) Class H01M 10/0568 (20130101) H01M 10/0569 (20130101) H01M 50/46 (20210101) H01M 2300/0042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230018570 | Anderson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brian L. Anderson (Lodi, California); Bill W. Colston (San Ramon, California); Christopher J. Elkin (Cranston, Rhode Island) |
| ABSTRACT | A system for nucleic acid amplification of a sample comprises partitioning the sample into partitioned sections and performing PCR on the partitioned sections of the sample. Another embodiment of the invention provides a system for nucleic acid amplification and detection of a sample comprising partitioning the sample into partitioned sections, performing PCR on the partitioned sections of the sample, and detecting and analyzing the partitioned sections of the sample. |
| FILED | Wednesday, July 14, 2021 |
| APPL NO | 17/305807 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 7/52 (20130101) Original (OR) Class B01L 2300/0829 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230019754 | Sant et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gaurav Sant (Los Angeles, California); Erika Callagon La Plante (Los Angeles, California); Jingbo Wang (Los Angeles, California); David Jassby (Los Angeles, California); Dante Simonetti (Los Angeles, California); Abdulaziz Alturki (Los Angeles, California); Xin Chen (Los Angeles, California) |
| ABSTRACT | Provided herein are methods of removing carbon dioxide from an aqueous stream or gaseous stream by: contacting the gaseous stream comprising carbon dioxide, when present, with an aqueous solution comprising ions capable of forming an insoluble carbonate salt; contacting the aqueous solution comprising carbon dioxide with an electroactive mesh that induces its alkalinization thereby forcing the precipitation of a carbonate solid from the solution and thereby the removal of dissolved inorganic carbon by electrolysis; and removing the precipitated carbonate solids from the solution, or the surface of the mesh where they may deposit. Also provided herein are flow-through electrolytic reactors comprising an intake device in fluid connection with a rotating cylinder comprising an electroactive mesh, and a scraping device and/or liquid-spray based device for separating a solid from the mesh surface. |
| FILED | Tuesday, July 26, 2022 |
| APPL NO | 17/873953 |
| CURRENT CPC | Separation B01D 53/62 (20130101) B01D 53/78 (20130101) B01D 53/965 (20130101) Original (OR) Class B01D 2251/402 (20130101) B01D 2251/404 (20130101) B01D 2252/1035 (20130101) B01D 2257/504 (20130101) B01D 2258/06 (20130101) B01D 2258/025 (20130101) B01D 2258/0233 (20130101) B01D 2258/0283 (20130101) Non-metallic Elements; Compounds Thereof; C01B 13/36 (20130101) C01B 32/60 (20170801) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/4618 (20130101) C02F 1/46109 (20130101) C02F 2001/4619 (20130101) C02F 2001/46133 (20130101) C02F 2001/46161 (20130101) C02F 2001/46171 (20130101) C02F 2103/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230019822 | PRESTON et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeffrey Robert PRESTON (Knoxville, Tennessee); Ashley C. STOWE (Knoxville, Tennessee) |
| ABSTRACT | A wide band gap semiconductor NAND based neutron detection system includes a semiconductor layer comprising a wide band gap material with a neutron absorber material in the wide band gap material, and the semiconductor layer is the only layer of the wide band gap semiconductor NAND based neutron detection system fabricated with the neutron absorber material. |
| FILED | Thursday, July 08, 2021 |
| APPL NO | 17/370366 |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/245 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0322 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230020052 | Nlebedlm et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Iowa State Univeresity Research Foundation,Inc (Ames, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Cajetan Ikenna Nlebedlm (Ames, Iowa); Abhishek Sarkar (Ames, Iowa); Pranav Shrotrlya (Ames, Iowa) |
| ABSTRACT | An efficient and green method for selective extraction of Li from end-of-life secondary LIBs of any capacity and size is provided. Electrochemical driven selective lithium deposition is targeted at the anode/separator interface of the end-of-life LIB. The deposited Li is recovered by processing of an opened or dismantled battery using only distilled or de-ionized water. The process not only enables the recovery of the plated lithium at the anode/separator interface, but also extracts the lithium from the organic salts and/or inorganic salts in the solid electrolyte interface (SEI) layers and from the electrolyte in the separator. In addition, the method partially strips the cyclable Li from the cathode and concentrates it at the anode/separator interface. The concentrated Li is extracted by using aqueous solution such as distilled or de-ionized water followed by recovery of the Li from aqueous solution. After Li recovery from the anode, the method can also enable the recovery of battery-grade graphite. |
| FILED | Thursday, June 30, 2022 |
| APPL NO | 17/803423 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/215 (20170801) Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor C25C 5/02 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/54 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230020187 | Kelly |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Energy, United States Department of (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bryce D. Kelly (Idaho Falls, Idaho) |
| ABSTRACT | The compact annular linear pump has a duct, with an inlet and an outlet, positioned to surround an inner core. The duct has a fluid with paramagnetic properties disposed within it. Surrounding the duct is a stator having a first end and a second end. The stator has a plurality of slots that is divisible by three. There is a tooth at each end of the stator and between each slot. There is an electromagnetic circuit with three conductors wired in series disposed within the stator. Within each slot is a coil. Each of the three conductors travel through the stator by alternating through pairs of slots, each coil belonging to a single conductor and alternating conductors every third coil pair. The fluid travels from the inlet to the outlet by application of a current generator to the electromagnetic circuit creating a magnetic flux. |
| FILED | Wednesday, July 14, 2021 |
| APPL NO | 17/375347 |
| CURRENT CPC | Dynamo-electric Machines H02K 44/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230020256 | WANG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Chunsheng WANG (Silver Spring, Maryland); Ji CHEN (College Park, Maryland); Xiulin FAN (College Park, Maryland) |
| ABSTRACT | The present invention provides an anode composition comprising (i) a core material (10) comprising a microparticle; (ii) a lithium alloy of said microparticle (14) on a surface of said core material (10); and (iii) a solid electrolyte interface (“SEI”) comprising (a) a LiF and (b) a polymer. The microparticle comprises Si, Al, Bi, Sn, Zn, or a mixture thereof. The present invention also relates to an electrolyte comprising a high lithium fluoride salt concentration in a low reduction potential solvent that is used produce the solid electrolyte interface comprising LiF and a polymer. The anode composition of the invention has an initial coulombic efficiency of at least 90%, a cycling coulombic efficiency of at least 99%, or both. |
| FILED | Friday, February 19, 2021 |
| APPL NO | 17/801260 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/134 (20130101) H01M 4/366 (20130101) Original (OR) Class H01M 10/0525 (20130101) H01M 10/0568 (20130101) H01M 2004/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230021214 | Lehmer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho); Virginia Commonwealth University (Richmond, Virginia); University of Idaho (Moscow, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jacob P. Lehmer (Idaho Falls, Idaho); Craig G. Rieger (Pocatello, Idaho); Bjorn C. Vaagensmith (Idaho Falls, Idaho); Tyler B. Phillips (Idaho Falls, Idaho); Timothy R. McJunkin (Idaho Falls, Idaho); Robert C. Ivans (Ammon, Idaho); Vivek Kumar Singh (Ammon, Idaho); Justin J. Welch (Idaho Falls, Idaho); Ruixuan Li (Idaho Falls, Idaho); Daniel Marino Lizarazo (Richmond, Virginia); Chathurika Mudiyanselage Wickramasinghe Brahmana Mudiyanselage (Richmond, Virginia); Milos Manic (Henrico, Virginia); Brian Johnson (Richmond, Virginia) |
| ABSTRACT | Tracking of health and resilience of physical equipment and related systems are disclosed. A system includes physical equipment and one or more processors. The physical equipment includes one or more assets. The one or more processors are configured to determine a resilience metric for the physical equipment. The resilience metric includes a real power component and a reactive power component based, at least in part, on an aggregation of real components and reactive components of adaptive capacities of the one or more assets. A cyber-physical system includes physical equipment, network equipment configured to enable the physical equipment to communicate over one or more networks, a physical anomaly detection system (ADS) configured to detect anomalies in operation of the physical equipment and provide a physical component of a cyber-physical metric, and a cyber ADS configured to detect anomalies in network communications over the one or more networks. |
| FILED | Monday, July 11, 2022 |
| APPL NO | 17/811843 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/36 (20130101) G01R 31/086 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 11/206 (20130101) G06T 2200/24 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 50/10 (20141201) Transmission of Digital Information, e.g Telegraphic Communication H04L 43/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230021218 | GADIKOTA |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Greeshma GADIKOTA (Ithaca, New York) |
| ABSTRACT | The present disclosure relates to methods for producing hydrogen and calcium- or magnesium-bearing carbonates by capturing, converting, and storing carbon dioxide. The methods may include providing one or more calcium- or magnesium-bearing compounds; providing one or more water-soluble oxygenates; providing a plurality of catalysts; and reacting one or more calcium- or magnesium-bearing compounds and one or more water-soluble oxygenates with plurality of catalysts under conditions to produce hydrogen and calcium- or magnesium-bearing carbonates. The methods may include providing one or more calcium- or magnesium-bearing silicates; providing carbon monoxide; providing water vapor; and reacting one or more calcium- or magnesium-bearing silicates, carbon monoxide, and water vapor. The methods may include providing one or more calcium- or magnesium-bearing compounds; providing one or more water-soluble oxygenates; providing a catalyst; and reacting one or more calcium- or magnesium-bearing compounds and one or more water-soluble oxygenates with said catalyst. |
| FILED | Monday, January 04, 2021 |
| APPL NO | 17/758257 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/04 (20130101) B01J 23/755 (20130101) B01J 31/20 (20130101) B01J 2231/76 (20130101) B01J 2531/821 (20130101) B01J 2531/842 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/20 (20130101) Original (OR) Class C01B 3/068 (20130101) Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 5/24 (20130101) C01F 11/183 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230021292 | Watkins et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicholas Watkins (Brentwood, California); N. Reginald Beer (Pleasanton, California); Melinda Simon (Fremont, California) |
| ABSTRACT | Devices, techniques, and processes are disclosed that use electrical impedance to detect of the presence and contents of droplets including cells, nucleic acids, proteins, or solute concentrations in an array of retrievable, trackable, trapped droplets in a fluidic system. Electrodes may be positioned underneath individual droplet traps in a microchannel to assay droplet contents and/or actuating droplets for the release of the droplets from corresponding traps. The disclosed technology may be used for detection of the results of solvent extraction processes including time-dependent quantification of metal ion concentration in the aqueous and organic phases, for wastewater treatment, heavy metal detection, pharmaceutical industry, and/or biotechnology, or for environmental monitoring of wastewater for toxic metal, monitoring of biological cell viability and proliferation, monitoring of extraction processes used in heavy metal mining, monitoring of extraction processes used in nuclear fuel processing, monitoring kinetics of enzyme processes, and/or assessing pharmacodynamics and drug efficacy. |
| FILED | Wednesday, August 10, 2022 |
| APPL NO | 17/818759 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0093 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/5025 (20130101) B01L 3/50273 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20230014658 | Seelig et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Georg Seelig (Seattle, Washington); Anna Kuchina (Seattle, Washington); Alexander B. Rosenberg (Seattle, Washington) |
| ABSTRACT | Methods of labeling or barcoding molecules within one or more portions of a plurality of cells are provided. Kits and systems for labeling or barcoding molecules within one or more portions of a plurality of cells are also provided. The methods, kits, and systems may utilize photo-controlled adapter sequences, nucleic acids tags, and/or linkers. |
| FILED | Thursday, July 14, 2022 |
| APPL NO | 17/864690 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1037 (20130101) C12N 15/1065 (20130101) Original (OR) Class C12N 15/1068 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 30/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230014799 | Maddox et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Mizar Imaging, LLC (Woods Hole, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul Samuel Maddox (Chapel Hill, North Carolina); Joel Carter Smith (East Falmouth, Massachusetts) |
| ABSTRACT | Devices, systems, and methods for imaging samples. In some examples, a device includes at least two basins for holding a liquid medium, the at least two basins including a sample chamber and a reservoir. The device includes a wedge between the sample chamber and the reservoir, and the wedge protrudes into the sample chamber and defines a space between the wedge and a bottom of the sample chamber. The space is sized for holding one or more biological samples. The device is formed to define a flow channel between the sample chamber and the reservoir, and the flow channel is shaped to allow the passage of the liquid medium from the sample chamber and the reservoir and to block passage of the one or more biological samples between the sample chamber and the reservoir. |
| FILED | Monday, December 07, 2020 |
| APPL NO | 17/782843 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50 (20130101) B01L 2300/161 (20130101) B01L 2400/0406 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/2813 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230015901 | Morin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen Morin (Lincoln, Nebraska); Ruiguo Yang (Lincoln, Nebraska); Karla Perez-Toralla (Lincoln, Nebraska); Mark Rose (Lincoln, Nebraska); Angel Olivera-Torres (Lincoln, Nebraska); John Kapitan (Lincoln, Nebraska); Grayson Minnick (Lincoln, Nebraska) |
| ABSTRACT | The invention provides a method for preparing an ordered cell-containing microarray, and a system for preparing an ordered cell-containing microarray. |
| FILED | Wednesday, June 15, 2022 |
| APPL NO | 17/840815 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 11/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230017478 | Thyagarajan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Associated Universities, Inc. (Washington, District of Columbia) |
| ASSIGNEE(S) | Associated Universities, Inc. (Washington, District of Columbia) |
| INVENTOR(S) | Nithyanandan Thyagarajan (Myaree, Australia); Christopher L. Carilli (Socorro, New Mexico) |
| ABSTRACT | Methods and systems of eliminating corrupting influences caused by the propagation medium and the data capture devices themselves from useful image features or characteristics such as the degree of symmetry are disclosed. The method includes the steps of obtaining image-plane data using a plurality of data capture devices, wherein the image-plane data is a combined visibility from each of the data capture devices, measuring the closure phase geometrically in the image-plane directly from the image-plane, removing the corruptions from the image features based on the measured closure phase to remove the non-ideal nature of the measurement process, and outputting the uncorrupted morphological features of the target object in the image. The method relies on the Shape-Orientation-Size conservation principle for images produced from three visibilities made from a closed triad of data capture devices. The method includes the idea that true image of the object can be reconstructed from the three interferometer elements, independent of element-based calibration. |
| FILED | Friday, July 09, 2021 |
| APPL NO | 17/784929 |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02007 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 17/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230018070 | Ji et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GROTTHUSS, INC. (ALBANY, Oregon) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xiulei Ji (Portland, Oregon); Heng Jiang (State College, Pennsylvania) |
| ABSTRACT | A rechargeable zinc metal battery cell includes a zinc metal anode, a cathode, a porous separator between them, and an electrolyte composition absorbed by the porous separator and in contact with both anode and cathode. The electrolyte composition includes (i) an aqueous solution of zinc chloride at a concentration greater than 15 molal, and (ii) dimethyl carbonate present at a mass ratio between 0.1:1.0 and 1.0:1.0 with respect to water in the aqueous solution. In some examples: the anode includes zinc metal foil stacked on titanium metal foil; the cathode includes vanadium(V) phosphate; the porous separator includes glass fibers and is less than 200 μm thick; or the electrolyte composition includes (i) an aqueous solution of 30 molal zinc chloride, 5 molal lithium chloride, and 10 molal trimethyl ammonium chloride, and (ii) dimethyl carbonate present at a mass ratio of 1.0:1.0 with respect to water in the aqueous solution. |
| FILED | Monday, July 18, 2022 |
| APPL NO | 17/867672 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/244 (20130101) Original (OR) Class H01M 10/26 (20130101) H01M 10/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230018807 | Pandolfino et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John Erik Pandolfino (Wilmette, Illinois); Neelesh Ashok Patankar (Buffalo Grove, Illinois); Shashank Acharya (Evanston, Illinois); Sourav Halder (Evanston, Illinois); Wenjun Kou (Rockford, Illinois); Peter James Kahrilas (Chicago, Illinois); Dustin Allan Carlson (Chicago, Illinois) |
| ABSTRACT | A fluid mechanics-based analysis tool is implemented to compute pressure field data, fluid velocity data, and/or muscular work data in a lumen or other tubular organ or structure from planimetry and pressure data (e.g., measured using a balloon dilation or other planimetry catheter). In this way, flow data can be estimated, which are otherwise insensible from current planimetry catheter technologies due to economic and/or manufacturing limitations. |
| FILED | Thursday, November 19, 2020 |
| APPL NO | 17/778340 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1076 (20130101) A61B 5/6853 (20130101) Original (OR) Class Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230019331 | Gans et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicholas R. Gans (Plano, Texas); Bashir H. Jafari (Dallas, Texas) |
| ABSTRACT | In an embodiment, a method for controlling a printer is provided. The method includes: receiving a set of parameters associated with a printer by a computing device, wherein the printer is depositing ink on a substrate to generate a line; measuring a width of the line by the computing device; receiving a duty cycle associated with the printer by the computing device; using the received duty cycle, the set of parameters, and a model, estimating one or more unknown parameters of the set of parameters by the computing device; receiving a desired width of the line by the computing device; and if the desired width is not the same as the measured width: adjusting the duty cycle associated with the printer based on the set of parameters and the model so that the measured width is closer to the desired width by the computing device. |
| FILED | Monday, September 12, 2022 |
| APPL NO | 17/931243 |
| CURRENT CPC | Typewriters; Selective Printing Mechanisms,, i.e Mechanisms Printing Otherwise Than From a Forme; Correction of Typographical Errors B41J 2/04586 (20130101) Original (OR) Class B41J 2/04593 (20130101) B41J 3/4073 (20130101) B41J 2202/21 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230019924 | Reiserer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ronald S. Reiserer (Nashville, Tennessee); Gregory B. Gerken (Nashville, Tennessee); David K. Schaffer (Nashville, Tennessee); John P. Wikswo (Brentwood, Tennessee) |
| ABSTRACT | A continuous automated perfusion culture analysis system (CAPCAS) comprises one or more fluidic systems configured to operate large numbers of biodevices in parallel. Each fluidic system comprises an input reservoir plate for receiving media; a biodevice plate comprising an array of biodevices fluidically coupled to the input reservoir plate, configured such that each biodevice has independent media delivery, fluid removal, stirring, and gas control, and each biodevice is capable of continuously receiving the media from the input reservoir plate; and an output plate fluidically coupled to the biodevice plate for real-time analysis and sampling. The operations of the CAPCAS are automated and computer-controlled wirelessly. The CAPCAS can also be used for abiotic and biotic chemical synthesis processes. |
| FILED | Monday, September 19, 2022 |
| APPL NO | 17/947302 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/08 (20130101) C12M 23/10 (20130101) C12M 23/12 (20130101) C12M 23/16 (20130101) C12M 23/50 (20130101) C12M 23/58 (20130101) C12M 27/02 (20130101) C12M 27/12 (20130101) C12M 29/10 (20130101) Original (OR) Class C12M 35/02 (20130101) C12M 35/04 (20130101) C12M 41/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230019960 | Huo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ke Huo (West Lafayette, Indiana); Karthik Ramani (West Lafayette, Indiana) |
| ABSTRACT | A method and system for localizing a plurality of stationary devices, such as Internet of Things (IoT devices), arranged in an environment is disclosed. A mobile device is configured to survey an environment to generate a three-dimensional map of the environment using simultaneous localization and mapping (SLAM) techniques. The mobile device and the stationary devices are equipped with wireless transceivers, such as Ultra-wideband radios, for measuring distances between the devices using wireless ranging techniques. Based on the measured distances, the mobile device is configured to determine locations of the stationary devices in a reference frame of the three-dimensional map. In some embodiments, the determined locations can be used to enable a variety of spatially aware augmented reality features and interactions between the mobile device and the stationary device. |
| FILED | Tuesday, September 20, 2022 |
| APPL NO | 17/933714 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0484 (20130101) Image Data Processing or Generation, in General G06T 11/00 (20130101) G06T 15/00 (20130101) G06T 2200/24 (20130101) Image or Video Recognition or Understanding G06V 20/20 (20220101) Original (OR) Class Wireless Communication Networks H04W 88/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230020112 | Hill et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Erik Hill (La Jolla, California); Sheldon Brown (La Jolla, California); Wesley Hawkins (La Jolla, California) |
| ABSTRACT | A data analysis and processing method includes forming an initial assembly of datasets comprising multiple entities, where each entity is a collection of variables and relationships that define how entities interact with each other, simulating an evolution of the initial assembly by performing multiple iterations in which a first iteration uses the initial assembly as a starting assembly, and querying, during the simulating, the evolution of the initial assembly, for datasets that meet an optimality criterion. |
| FILED | Friday, July 01, 2022 |
| APPL NO | 17/810543 |
| CURRENT CPC | Card, Board, or Roulette Games; Indoor Games Using Small Moving Playing Bodies; Video Games; Games Not Otherwise Provided for A63F 13/69 (20140902) Electric Digital Data Processing G06F 9/455 (20130101) G06F 16/245 (20190101) Computer Systems Based on Specific Computational Models G06N 3/126 (20130101) Original (OR) Class Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/70 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230020716 | Mehrvand et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Eden GeoPower, Inc. (Somerville, Massachusetts) |
| ASSIGNEE(S) | Eden GeoPower, Inc. (Somerville, Massachusetts) |
| INVENTOR(S) | Mehrdad Mehrvand (Somerville, Massachusetts); Ammar Alali (Somerville, Massachusetts) |
| ABSTRACT | Systems and methods for deployment of electric-based fracturing tools in vertical wells are disclose. A method of electric-based fracturing may include lowering an electrical stimulation tool into a wellbore using a drill pipe and isolating a lower portion of the wellbore that is downhole from an upper portion of the wellbore. The electrical stimulation tool may be disposed in the lower portion of the wellbore. A system for electric-based fracturing may include an isolation mechanism and an electrical stimulation tool. The isolation mechanism may be configured to expand from a retracted configuration spaced from an interior surface of a wellbore to an expanded configuration in contact with the inner surface of the wellbore. The electrical stimulation tool may be operatively coupled with the isolation mechanism and may be configured to be disposed distally relative to the isolation mechanism when positioned in the wellbore. |
| FILED | Thursday, July 15, 2021 |
| APPL NO | 17/376842 |
| CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 33/16 (20130101) E21B 43/26 (20130101) Original (OR) Class E21B 43/2401 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230020770 | Alali et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Eden GeoPower, Inc. (Somerville, Massachusetts) |
| ASSIGNEE(S) | Eden GeoPower, Inc. (Somerville, Massachusetts) |
| INVENTOR(S) | Ammar Alali (Somerville, Massachusetts); Mehrdad Mehrvand (Somerville, Massachusetts) |
| ABSTRACT | Downhole tools, systems, and methods for electric-based fracturing are disclosed. A downhole tool for electric-based fracturing may include an outer enclosure, an insulator chamber disposed at least partially within the enclosure, and an electrode disposed at least partially within the insulator chamber. The electrode may extend out from the insulator chamber and the enclosure, and may be configured to transfer electric energy to an exterior environment surrounding the downhole tool. The insulator chamber may be configured to thermally and electrically insulate at least a portion of the electrode from the exterior environment. |
| FILED | Thursday, July 15, 2021 |
| APPL NO | 17/376809 |
| CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 17/028 (20130101) E21B 43/26 (20130101) Original (OR) Class E21B 43/2401 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 20230012496 | Ling et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Southwest Research Institute (San Antonio, Texas); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jian Ling (Spring Branch, Texas); Kreg A. Zimmern (San Antonio, Texas); Michael C. Milone (Philadelphia, Pennsylvania) |
| ABSTRACT | Described herein is a beads-free bioprocessor as an automated and cost-effective T cell processing and manufacturing platform. T cells are a core component in CAR T cell therapies for cancer treatment, but are difficult to manufacture to scale in clinically relevant quantities. The 3D bioprocessor provides an alternative device that is scalable, beads-free, easy-to-use, and cost-effective for using CAR T cell therapy in cancer immunotherapy. Besides CAR T cell application, this platform technology has potential for many other applications such as cancer cell isolation. |
| FILED | Monday, September 26, 2022 |
| APPL NO | 17/935259 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/02 (20130101) Original (OR) Class C12M 23/20 (20130101) C12M 25/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54313 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230014738 | Mirowski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Caliber MRI, Inc. (Boulder, Colorado) |
| ASSIGNEE(S) | Caliber MRI, Inc. (Boulder, Colorado) |
| INVENTOR(S) | Elizabeth Mirowski (Nederland, Colorado); Michael Snow (Erie, Colorado) |
| ABSTRACT | Provided herein are adipose mimic compositions for use in MRI. The compositions of the invention mimic the MRI properties of human adipose tissue, including T1 relaxation kinetics, T2 relaxation kinetics, magnetic susceptibility, and chemical shift artifact. The compositions of the invention are readily manufactured from inexpensive materials. The compositions of the invention may be used in MRI system calibration or for implementing image correction techniques such as fat suppression. |
| FILED | Sunday, September 18, 2022 |
| APPL NO | 17/933109 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/12 (20130101) A61K 49/06 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/58 (20130101) Original (OR) Class G01R 33/4828 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/10 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230017010 | Gorman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jason John Gorman (Silver Spring, Maryland); Thomas Warren LeBrun (Washington, District of Columbia); David Alexander Long (Bethesda, Maryland) |
| ABSTRACT | An optomechanical accelerometer includes: a fiducial mass for a microscale Fabry-Perot optical cavity; a proof mass for the microscale Fabry-Perot optical cavity, such that the proof mass oscillates in a displacement motion toward and away from the fiducial mass in response to acceleration of the optomechanical accelerometer; a basal member; microscale beams that mechanically suspend the proof mass from the basal member; and the microscale Fabry-Perot optical cavity that has a cavity resonance at a cavity resonance wavelength provided by the cavity length, receives excitation radiation at an excitation wavelength that is reflected in the cavity as dynamic cavity light when the excitation wavelength is resonant with the cavity resonance wavelength, and transmits the dynamic cavity light as cavity output light when the dynamic cavity light is produced from the excitation radiation. |
| FILED | Wednesday, June 30, 2021 |
| APPL NO | 17/363354 |
| CURRENT CPC | Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/093 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 20230015785 | COLE |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Craig Alan COLE (Farmington, Minnesota) |
| ABSTRACT | A method, a computing device, and a computer program product are provided. An interceptor hub application executing on a first computing device receives, via a network, a request for multiple services from a first service-consuming application executing on a second computing device. The multiple services execute on at least one other computing device and are accessible via the first computing device via the network. The interceptor hub application sends a respective request to each of the requested services executing on a corresponding one of the at least one other computing device. A respective service response from the each of the respective services is received by the interceptor hub application, which provides each of the respective responses in a combined service response to the first service-consuming. |
| FILED | Monday, May 23, 2022 |
| APPL NO | 17/750759 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/547 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/51 (20220501) H04L 67/63 (20220501) Original (OR) Class H04L 67/133 (20220501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230019383 | FOXX-GRUENSTEIDL |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Manfred FOXX-GRUENSTEIDL (Amissville, Virginia) |
| ABSTRACT | A system for processing delivery items, the system including a delivery item monitoring device comprising one or more sensor and a processor that is communicatively connected to the delivery item monitoring device and that is configured to perform operations comprising obtaining sensor data from the one or more sensor. The operations can also include calculating a depth of the received delivery items in the container based on the sensor data and generating an under-filled indicator, a transport indicator, or an over-filled indicator based on the depth of the received delivery items in the container. Furthermore, the operations can include transmitting the under-filled indicator, the transport indicator, or the over-filled indicator to a control system, wherein the under-filled indicator, the transport indicator, and the over-filled indicator designate how to process the container to the control system. |
| FILED | Tuesday, September 27, 2022 |
| APPL NO | 17/953913 |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/22 (20130101) Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 17/00 (20130101) Original (OR) Class G01F 25/0092 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230021053 | Dearing et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen M. Dearing (Herndon, Virginia); C. Scot Atkins (Chantilly, Virginia); James DeForrest Wilson (Collierville, Tennessee); Scott R. Bombaugh (Burke, Virginia); Carla F. Sherry (Annandale, Virginia) |
| ABSTRACT | Systems and methods for handling a plurality items by using a sorter to receive items and obtain item information and delivery destinations from the items. A run manifest is generated having an item identifier and a destination for each of the plurality of items. The run manifest data is used in a routing module to generate dynamic routes for delivering the plurality of items, and generating a sequence identifier for each of the plurality of items according to the dynamically generated routes. |
| FILED | Wednesday, September 28, 2022 |
| APPL NO | 17/936326 |
| CURRENT CPC | Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 3/00 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/08355 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20230015700 | Masoud et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents of Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sara Masoud (Tucson, Arizona); Young-Jun Son (Tucson, Arizona); Russell E. Tronstad (Tucson, Arizona); Chieri Kubota (Columbus, Ohio) |
| ABSTRACT | A simulation-based framework for optimizing resource allocation and layout design is disclosed. |
| FILED | Wednesday, September 07, 2022 |
| APPL NO | 17/939924 |
| CURRENT CPC | Electric Digital Data Processing G06F 30/13 (20200101) Original (OR) Class G06F 30/20 (20200101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/043 (20130101) G06Q 10/0633 (20130101) G06Q 10/06393 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230017534 | Hollar |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wiser Systems, Inc. (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Seth Edward-Austin Hollar (Raleigh, None) |
| ABSTRACT | Methods for determining a location of an unknown device (UD) from a plurality of known devices (KDs) are provided including receiving, at the UD, periodically broadcasted messages from each of a plurality of KDs. Corresponding arrival time stamp (Tarrival-i-UD) of each periodically broadcasted message from each of the plurality of KDs are recorded. Each of the plurality of KDs are clock synchronized to a common clock source at a master device(MD). A departure time of the periodically broadcasted message from each of the plurality of KDs is known by the UD in master device time units (Tdepart-i-md). X, y and z coordinates of a location of each of the KDs is known by the UD. The x, y and z coordinates of an actual location of the UD is calculated using the x, y and z coordinates of each of the KDs, the recorded arrival times (Tarrival-i-UD) of each of the periodically broadcasted messages from each of the plurality of KDs and the known departure times of each of the periodically broadcasted messages (Tdepart-i-md) from each of the plurality of KDs. |
| FILED | Monday, September 12, 2022 |
| APPL NO | 17/942273 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/00 (20130101) G01S 5/14 (20130101) G01S 5/021 (20130101) G01S 5/0218 (20200501) G01S 5/0263 (20130101) G01S 11/08 (20130101) Broadcast Communication H04H 20/18 (20130101) Wireless Communication Networks H04W 56/006 (20130101) H04W 56/007 (20130101) H04W 56/0015 (20130101) Original (OR) Class H04W 56/0025 (20130101) H04W 56/0065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20230014279 | Kochergin |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vladimir Kochergin (Christiansburg, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vladimir Kochergin (Christiansburg, Virginia) |
| ABSTRACT | The present invention relates to charged particle, X-ray, gamma ray and or thermal neutron attenuators on the basis of micro structured semiconductor and method of making the same. In more detail, the present invention is related to three-dimensionally microstructured charged particle, X-ray, gamma ray and or thermal neutron attenuators. The attenuators of the present invention will improve the performance of telescopes, radiology equipment, nondestructive evaluation equipment and proton therapy equipment. |
| FILED | Friday, July 16, 2021 |
| APPL NO | 17/377800 |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/24 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230019924 | Reiserer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ronald S. Reiserer (Nashville, Tennessee); Gregory B. Gerken (Nashville, Tennessee); David K. Schaffer (Nashville, Tennessee); John P. Wikswo (Brentwood, Tennessee) |
| ABSTRACT | A continuous automated perfusion culture analysis system (CAPCAS) comprises one or more fluidic systems configured to operate large numbers of biodevices in parallel. Each fluidic system comprises an input reservoir plate for receiving media; a biodevice plate comprising an array of biodevices fluidically coupled to the input reservoir plate, configured such that each biodevice has independent media delivery, fluid removal, stirring, and gas control, and each biodevice is capable of continuously receiving the media from the input reservoir plate; and an output plate fluidically coupled to the biodevice plate for real-time analysis and sampling. The operations of the CAPCAS are automated and computer-controlled wirelessly. The CAPCAS can also be used for abiotic and biotic chemical synthesis processes. |
| FILED | Monday, September 19, 2022 |
| APPL NO | 17/947302 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/08 (20130101) C12M 23/10 (20130101) C12M 23/12 (20130101) C12M 23/16 (20130101) C12M 23/50 (20130101) C12M 23/58 (20130101) C12M 27/02 (20130101) C12M 27/12 (20130101) C12M 29/10 (20130101) Original (OR) Class C12M 35/02 (20130101) C12M 35/04 (20130101) C12M 41/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20230013068 | Lin |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bioenno Tech LLC (Santa Ana, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhigang Lin (Santa Ana, California) |
| ABSTRACT | High voltage, high-ionic-conductivity, fire resistant solid-state polymer electrolytes include poly(vinylidene fluoride-co-hexafluoropropylene) P(VDF-HFP), sulfolane plasticizer, lithium salt, and ceramic nanoparticles with the basic formula Li7La3Zr2O12 (LLZO) and derivatives thereof. During the curing process, the presence of the LLZO nanoparticles prevent the P(VDF-HFP) from developing into a crystalline phase. In the electrolyte formed, the P(VDF-HFP) is in an amorphous phase with LLZO nanoparticles, lithium salt and sulfolane distributed in the polymer matrix. The solid-state electrolyte with the amorphous polymer phase exhibit higher ionic conductivities than those having a crystalline polymer phase. The LLZO contributes to mechanical properties of the electrolyte and also function as tough ceramic fillers that inhibit lithium dendrite growth during operation of lithium-ion cells and batteries. 5V all-solid-state lithium-ion batteries incorporated the electrolytes exhibit high energy densities (250-350 Whr/kg), high power densities (high discharge rate up to 5 C) and long service lives (500-1500 cycles, <2% irreversible loss/month). |
| FILED | Friday, September 09, 2022 |
| APPL NO | 17/942095 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/056 (20130101) Original (OR) Class H01M 10/0525 (20130101) H01M 10/0585 (20130101) H01M 50/414 (20210101) H01M 50/497 (20210101) H01M 2300/0071 (20130101) H01M 2300/0082 (20130101) H01M 2300/0091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230018070 | Ji et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GROTTHUSS, INC. (ALBANY, Oregon) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xiulei Ji (Portland, Oregon); Heng Jiang (State College, Pennsylvania) |
| ABSTRACT | A rechargeable zinc metal battery cell includes a zinc metal anode, a cathode, a porous separator between them, and an electrolyte composition absorbed by the porous separator and in contact with both anode and cathode. The electrolyte composition includes (i) an aqueous solution of zinc chloride at a concentration greater than 15 molal, and (ii) dimethyl carbonate present at a mass ratio between 0.1:1.0 and 1.0:1.0 with respect to water in the aqueous solution. In some examples: the anode includes zinc metal foil stacked on titanium metal foil; the cathode includes vanadium(V) phosphate; the porous separator includes glass fibers and is less than 200 μm thick; or the electrolyte composition includes (i) an aqueous solution of 30 molal zinc chloride, 5 molal lithium chloride, and 10 molal trimethyl ammonium chloride, and (ii) dimethyl carbonate present at a mass ratio of 1.0:1.0 with respect to water in the aqueous solution. |
| FILED | Monday, July 18, 2022 |
| APPL NO | 17/867672 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/244 (20130101) Original (OR) Class H01M 10/26 (20130101) H01M 10/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 20230016147 | Fry |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Mark A. Fry (Marco Island, Florida) |
| ABSTRACT | Systems and methods for training an artificial intelligence (AI) classifier of scanned items. The items may include a training set of sample raw scans. The set may include in-class objects and not-in-class raw scans. An AI classifier may be configured to sample raw scans in the training set, measure errors in the results, update classifier parameters based on the errors, and detect completion of training. |
| FILED | Thursday, June 02, 2022 |
| APPL NO | 17/830939 |
| CURRENT CPC | Image or Video Recognition or Understanding G06V 10/70 (20220101) G06V 10/235 (20220101) Original (OR) Class G06V 10/248 (20220101) G06V 10/255 (20220101) G06V 10/945 (20220101) G06V 2201/07 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20230018447 | Ferguson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John Ferguson (Minneapolis, Minnesota); Gregory Owen Voss (Apple Valley, Minnesota); Stuart Richard Fairhurst (South Saint Paul, Minnesota); Andrew Hansen (Apple Valley, Minnesota) |
| ABSTRACT | Disclosed herein are devices, systems, and methods for measuring socket fit in lower limb prostheses and detecting motion of a residual limb relative to a prosthetic socket. Also disclosed herein are methods for developing a socket-fit detection system for sock management that can be applied to adjustable socket systems. |
| FILED | Thursday, July 21, 2022 |
| APPL NO | 17/870445 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/103 (20130101) A61B 5/4851 (20130101) A61B 5/6811 (20130101) A61B 2562/0219 (20130101) A61B 2562/0247 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/68 (20130101) A61F 2/76 (20130101) A61F 2/80 (20130101) Original (OR) Class A61F 2002/689 (20130101) A61F 2002/6827 (20130101) A61F 2002/7635 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 20230015217 | Starkovich et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northrop Grumman Systems Corporation (Falls Church, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John A. Starkovich (Redondo Beach, California); Edward M. Silverman (Encino, California) |
| ABSTRACT | A high-performance optical absorber is provided having a texturized base layer. The base layer has one or more of a polymer film and a polymer coating. A surface layer is located above and immediately adjacent to the base layer and the surface layer joined to the base layer. The surface layer comprises a plasma-functionalized, non-woven carbon nanotube (CNT) sheet, wherein the base layer texturization comprises one or more of substantially rectangular ridges, substantially triangular ridges, substantially pyramidal ridges, and truncated, substantially pyramidal ridges. The CNT sheet has a thickness greater than or equal to 10×λ, where λ is the wavelength of the incident light. In certain embodiments the base layer has a height above the surface layer greater than or equal to 10×λ, where λ is the wavelength of the incident light. |
| FILED | Monday, September 19, 2022 |
| APPL NO | 17/947375 |
| CURRENT CPC | Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/0074 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Optical Elements, Systems, or Apparatus G02B 5/003 (20130101) Original (OR) Class G02B 2207/101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230015280 | ROBINSON |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rampart Communications, Inc. (Annapolis, Maryland) |
| ASSIGNEE(S) | Rampart Communications, Inc. (Annapolis, Maryland) |
| INVENTOR(S) | Matthew Brandon ROBINSON (Crownsville, Maryland) |
| ABSTRACT | A processor coupled to a first communication device produces and transmits a first encoded vector and a second encoded vector to a second communication device via a communication channel that applies a channel transformation to the encoded vectors during transmission. A processor coupled to the second communication device receives the transformed signals, constructs a matrix based on the transformed signals, detects an effective channel thereof, and identifies left and right singular vectors of the effective channel. A precoding matrix is selected from a codebook of unitary matrices based on a message, and a second encoded vector is produced based on a second known vector, the precoding matrix, a complex conjugate of the left singular vectors, and the right singular vectors. A first symbol of the second encoded vector and a second symbol of the second encoded vector are sent to the first communication device for identification of the message. |
| FILED | Monday, September 26, 2022 |
| APPL NO | 17/953276 |
| CURRENT CPC | Transmission H04B 7/0417 (20130101) H04B 7/0456 (20130101) H04B 7/0634 (20130101) Original (OR) Class H04B 7/0639 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230015299 | WARE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RAYTHEON BBN TECHNOLOGIES CORP. (Cambridge, Massachusetts); Columbia University (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew Elliott WARE (Arlington, Massachusetts); Anjaly Thekkevilayil RAJENDRAN (New York, New York); Guilhem Jean Antoine RIBEILL (Arlington, Massachusetts); Thomas OHKI (Arlington, Massachusetts); James Curtis HONE (New York, New York); Martin GUSTAFSSON (Cambridge, Massachusetts); Luke GOVIA (Somerville, Massachusetts); Kin Chung FONG (Concord, Massachusetts); Abhinandan ANTONY (New York, New York) |
| ABSTRACT | A van der Waals capacitor and a qubit constructed with such a capacitor. In some embodiments, the capacitor includes a first conductive layer; an insulating layer, on the first conductive layer; and a second conductive layer on the insulating layer. The first conductive layer may be composed of one or more layers of a first van der Waals material, the insulating layer may be composed of one or more layers of a second van der Waals material, and the second conductive layer may be composed of one or more layers of a third van der Waals material. |
| FILED | Friday, March 04, 2022 |
| APPL NO | 17/686832 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 4/008 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/223 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230016764 | Boroughs |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Grant B. Boroughs (Southlake, Texas) |
| ABSTRACT | A computer-implemented system and method of image cross-correlation improves the sub-pixel accuracy of the correlation surface and subsequent processing thereof. One or both of the template or search windows are resampled using the fractional portions of the correlation offsets X and Y produced by the initial image cross-correlation. The resampled window is then correlated with the other original window to produce a resampled cross-correlation surface. Removing the fractional or sub-pixel offsets between the template and search windows improves the “sameness” of the represented imagery thereby improving the quality and accuracy of the correlation surface, which in turn improves the quality and accuracy of the FOM or other processing of the correlation surface. The process may be iterated to improve accuracy or modified to generate resampled cross-correlation surfaces for multiple possible offsets and to accept the one with the most certainty. |
| FILED | Friday, July 16, 2021 |
| APPL NO | 17/378113 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/32 (20170101) Original (OR) Class G06T 7/38 (20170101) G06T 7/215 (20170101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230019017 | GRANINGER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | AURELIUS L. GRANINGER (SYKESVILLE, Maryland); AARON A. PESETSKI (GAMBRILLS, Maryland); JOEL D. STRAND (ELLICOTT CITY, Maryland) |
| ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (FALLS CHURCH, Virginia) |
| INVENTOR(S) | AURELIUS L. GRANINGER (SYKESVILLE, Maryland); AARON A. PESETSKI (GAMBRILLS, Maryland); JOEL D. STRAND (ELLICOTT CITY, Maryland) |
| ABSTRACT | A superconducting AC switch system includes a switch network configuration comprising a Josephson junction (JJ) coupled to a transmission line having a transmission line impedance, and a magnetic field generator that is configured to switch from inducing a magnetic field in a plane of the JJ, and providing no magnetic field in the plane of the JJ. An AC input signal applied at an input of the switch network configuration is passed through to an output of the switch network configuration in a first magnetic state, and substantially reflected back to the input of the switch network configuration in a second magnetic state. The first magnetic state is one of inducing and not inducing a magnetic field in a plane of the JJ, and the second magnetic state is the other of inducing and not inducing a magnetic field in a plane of the JJ. |
| FILED | Wednesday, July 14, 2021 |
| APPL NO | 17/375210 |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 7/064 (20130101) Pulse Technique H03K 17/92 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, January 19, 2023.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-applications-20230119.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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