FedInvent™ Patent Applications
Application Details for Thursday, March 02, 2023
This page was updated on Friday, March 03, 2023 at 05:40 AM GMT
Department of Health and Human Services (HHS)
| US 20230060304 | Connors et al. |
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| FUNDED BY |
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| APPLICANT(S) | The U.S.A, as represented by the Secretary, Department of Health and Human Service (Bethesda, Maryland) |
| ASSIGNEE(S) | The U.S.A, as represented by the Secretary, Department of Health and Human Service (Bethesda, Maryland) |
| INVENTOR(S) | Mark Connors (Bethesda, Maryland); Jinghe Huang (Derwood, Maryland); Byong Ha Kang (Rockville, Maryland); John Mascola (Rockville, Maryland); Elise Ishida (Chevy Chase, Maryland); Tongqing Zhou (Boyds, Maryland); Peter Kwong (Washington, District of Columbia); Anqi Zheng (Boyds, Maryland) |
| ABSTRACT | Antibodies and antigen binding fragments that specifically bind to gp120 and neutralize HIV-1 are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. Methods for detecting HIV-1 using these antibodies are disclosed. In addition, the use of these antibodies, antigen binding fragment, nucleic acids and vectors to prevent and/or treat an HIV-1 infection is disclosed. |
| FILED | Thursday, June 30, 2022 |
| APPL NO | 17/855553 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) Peptides C07K 16/468 (20130101) C07K 16/1063 (20130101) Original (OR) Class C07K 16/2809 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56988 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230060376 | Voss et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James Even Voss (San Diego, California); Raiees Andrabi (San Diego, California); Dennis R. Burton (La Jolla, California); Deli Huang (La Jolla, California); Alicia Gonzalez-Martin (Madrid, Spain) |
| ABSTRACT | Methods and systems are described herein for generating engineered B cells with modified immunoglobulin genes. The modified immunoglobulin genes encode modified immunoglobulins that can have high affinity for antigens, including antigens that are variable such the types of antigens on various pathogens that can escape mammalian immune responses. |
| FILED | Friday, August 03, 2018 |
| APPL NO | 16/642810 |
| CURRENT CPC | Peptides C07K 16/1045 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230060792 | Deng et al. |
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| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xingming Deng (Atlanta, Georgia); Guo Chen (Atlanta, Georgia); Abu Syed Md Anisuzzaman (Atlanta, Georgia) |
| ABSTRACT | This disclosure relates to inhibitors of Mcl-1 stimulated homologous recombination (HR) DNA repair and uses for treating cancer. In certain embodiments, this disclosure relates to methods of treating cancer comprising administering an inhibitor of Mcl-1 in combination with other anti-cancer agents, e.g., that induce DNA replication stress. In certain embodiments, this disclosure relates to methods of treating cancer comprising administering compounds disclosed herein in combination with hydroxyurea, olaparib, or combinations thereof. |
| FILED | Friday, October 28, 2022 |
| APPL NO | 17/976168 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/15 (20130101) A61K 31/17 (20130101) A61K 31/343 (20130101) Original (OR) Class A61K 31/502 (20130101) A61K 31/517 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230060867 | HEATON et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicholas S. HEATON (Durham, North Carolina); Alfred HARDING (Durham, North Carolina); Griffin HAAS (New York, New York); Alanson GIRTON (Frederick, Maryland) |
| ABSTRACT | The present invention provides a modified influenza A virus (IAV) comprising, consisting of, or consisting essentially of at least one artificial gene segment comprising a duplicated packaging signal, the result of which is a modified IAV that is replication competent and avirulent, and when co-infected with a wild type virus leads to segment exchange and compromises the spread of both viruses as well as methods of making and using same and methods of using the IAVs in the treatment and prevention of influenza-related diseases. |
| FILED | Friday, February 07, 2020 |
| APPL NO | 17/428921 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0043 (20130101) A61K 39/145 (20130101) Original (OR) Class A61K 2039/5252 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/16 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/09 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230060873 | Chanda et al. |
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| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri); Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri); Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Baron Chanda (St. Louis, Missouri); Willy Carrasquel Ursulaez (St. Louis, Missouri); Jennifer Schomaker (Madison, Wisconsin); Corey Jones (Linden, Tennessee); Mahzad Dehghany (Madison, Wisconsin) |
| ABSTRACT | Self-assembling compounds for the formation of ion channels in biological membranes include monoacylated benzo(crown-ether) (MAcBCE) compounds and monoalkylated benzo(crown-ether) (MAkBCE) compounds. Methods of preparing the MAcBCE and MAkBCE compounds and methods of forming an ion channel in a biological membrane are also disclosed. |
| FILED | Thursday, August 04, 2022 |
| APPL NO | 17/881038 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/357 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230060990 | Chiosis et al. |
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| FUNDED BY |
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| APPLICANT(S) | Sloan-Kettering Institute for Cancer Research (New York, New York) |
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| INVENTOR(S) | Gabriela Chiosis (New York, New York); Huazhong He (New York, New York); Danuta Zatorska (Ericeira, Portugal) |
| ABSTRACT | Treatment of neurodegenerative diseases is achieved using small molecule purine scaffold compounds that inhibit Hsp90 and that possess the ability to cross the blood-brain barrier or are otherwise delivered to the brain. |
| FILED | Friday, October 15, 2021 |
| APPL NO | 17/502563 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/52 (20130101) Heterocyclic Compounds C07D 473/40 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230060997 | NDINGURI et al. |
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| APPLICANT(S) | EASTERN KENTUCKY UNIVERSITY (Richmond, Kentucky) |
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| INVENTOR(S) | Margaret NDINGURI (Richmond, Kentucky); Lindsay CORMIER (Richmond, Kentucky) |
| ABSTRACT | The present disclosure concerns luteinizing hormone receptor hormone (LHRH) compositions that can selectively bind to an LHRH receptor. Through the incorporation of radionuclides in the LHRH compositions, selective radiolabeling is made possible, allowing for identification of cells over-expressing the LHRH receptor, which is often a facet of an abnormally growing cell or a tumorigenic cell. The LHRH compositions can therefore provide for improved detection and monitoring of cancers associated with or caused by LHRH receptor over-expression. |
| FILED | Thursday, January 14, 2021 |
| APPL NO | 17/792571 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/088 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230061218 | Soh et al. |
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| FUNDED BY |
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| APPLICANT(S) | CHAN ZUCKERBERG BIOHUB, INC. (San Francisco, California); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
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| INVENTOR(S) | Hyongsok Soh (Stanford, California); Mahla Poudineh (Stanford, California); Jing Pan (Stanford, California) |
| ABSTRACT | The present disclosure provides materials and methods for the continuous measurement of biomolecules in vivo and in real-time. The present disclosure relates more specifically to using capture agents and detection agents within a microfluidic device to detect and quantify biochemical features of biomarkers, enabling real-time detection and concentration measurements. |
| FILED | Friday, January 15, 2021 |
| APPL NO | 17/793205 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0071 (20130101) A61B 5/0077 (20130101) A61B 5/1455 (20130101) A61B 5/14532 (20130101) A61B 5/14535 (20130101) A61B 5/14865 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54366 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230061432 | Du et al. |
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| FUNDED BY |
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| APPLICANT(S) | Lin Du (Norman, Oklahoma); April Risinger (San Antonio, Texas); Samantha Yee (San Antonio, Texas) |
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| INVENTOR(S) | Lin Du (Norman, Oklahoma); April Risinger (San Antonio, Texas); Samantha Yee (San Antonio, Texas) |
| ABSTRACT | The present disclosure is concerned with taccalonolide analogs and conjugated taccalonolide analogs useful as cellular probes and in the treatment of, for example, hyperproliferative disorders such as cardiovascular diseases and cancer. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Friday, March 06, 2020 |
| APPL NO | 17/437379 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/585 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Steroids C07J 53/002 (20130101) Original (OR) Class C07J 71/0005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230061571 | Forghanian-Arani et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Arvin Forghanian-Arani (Rochester, Minnesota); Joshua D. Trzasko (Rochester, Minnesota); Yi Sui (Rochester, Minnesota); Philip A. Araoz (Rochester, Minnesota); Richard L. Ehman (Rochester, Minnesota); John Huston, III (Rochester, Minnesota) |
| ABSTRACT | Described here are systems and methods for a robust magnetic resonance elastography (“MRE”) imaging platform for rapid dynamic 3D MRE imaging. The imaging platform includes an MRE pulse sequence and advanced image reconstruction framework that work synergistically in order to greatly expand the domains where MRE can be deployed successfully. |
| FILED | Friday, January 15, 2021 |
| APPL NO | 17/793633 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0044 (20130101) A61B 5/0051 (20130101) A61B 5/055 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4818 (20130101) G01R 33/56358 (20130101) G01R 33/56375 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 11/003 (20130101) G06T 2210/41 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230061665 | SPANIEL et al. |
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| FUNDED BY |
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| APPLICANT(S) | NATIONAL INSTITUTE OF MENTAL HEALTH (Klecany, Czech Republic) |
| ASSIGNEE(S) | NATIONAL INSTITUTE OF MENTAL HEALTH (Klecany, Czech Republic) |
| INVENTOR(S) | Filip SPANIEL (Zdiby, Czech Republic); Vaclav CAPEK (Borotin, Czech Republic); Antonin SKOCH (Prague, Czech Republic) |
| ABSTRACT | Methods of categorisation of schizophrenia sufferers into subtypes based on changes in brain morphology, together with associated blood biomarkers are provided. The methods allow for more accurate treatment and diagnosis of schizophrenia. |
| FILED | Friday, January 15, 2021 |
| APPL NO | 17/793213 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) Original (OR) Class A61B 5/0515 (20130101) A61B 5/4064 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230061715 | SCHELLENBERGER et al. |
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| FUNDED BY |
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| APPLICANT(S) | Amunix Pharmaceuticals, Inc. (South San Francisco, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Volker SCHELLENBERGER (Palo Alto, California); Joshua SILVERMAN (Los Altos Hills, California); Chia-wei WANG (Santa Clara, California); Benjamin SPINK (San Carlos, California); Willem P.C STEMMER (Los Gatos, California); Nathan C. GEETHING (Santa Clara, California) |
| ABSTRACT | The present invention relates to binding fusion protein compositions comprising targeting moieties linked to extended recombinant polypeptide (XTEN), binding fusion protein-drug conjugate compositions, and XTEN-drug conjugate compositions, isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of diseases, disorders, and conditions. |
| FILED | Thursday, February 24, 2022 |
| APPL NO | 17/680070 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/00 (20130101) C07K 14/7155 (20130101) C07K 14/8125 (20130101) C07K 14/70521 (20130101) C07K 16/18 (20130101) C07K 16/32 (20130101) C07K 16/40 (20130101) C07K 16/241 (20130101) C07K 16/244 (20130101) C07K 16/2809 (20130101) C07K 16/2863 (20130101) C07K 16/2878 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/625 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230061751 | Khvorova et al. |
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| APPLICANT(S) | UNIVERSITY OF MASSACHUSETTS (Bostton, Massachusetts) |
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| INVENTOR(S) | Anastasia Khvorova (Westborough, Massachusetts); Bruno Miguel da Cruz Godinho (Worcester, Massachusetts); Matthew Hassler (Worcester, Massachusetts) |
| ABSTRACT | Therapeutic oligonucleotides comprising universal pharmacokinetic (PK)-modifying anchors are provided. Methods for treating diseases or disorders comprising administering to a subject a therapeutic oligonucleotide comprising one or more universal PK-modifying anchors are provided. |
| FILED | Friday, January 15, 2021 |
| APPL NO | 17/792705 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/52 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230061804 | GARCIA QUIROZ et al. |
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| APPLICANT(S) | THE ROCKEFELLER UNIVERSITY (New York, New York) |
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| INVENTOR(S) | Felipe GARCIA QUIROZ (New York, New York); Elaine FUCHS (New York, New York) |
| ABSTRACT | The present invention provides phase separation sensors capable of targeting or associating with one or more biomolecular condensate or membraneless compartment in cells. The phase separation sensors comprise at least two domains wherein a first domain comprises one or more accessory protein or molecule and a second domain comprises an artificial client protein or intrinsically disordered sequence. The artificial client protein possesses intrinsic disorder and is capable of engaging in ultra-weak phase separation-specific interactions with one or more component protein or molecule in a biomolecular condensate. Methods and applications utilizing the sensors are provided including targeting, detecting, visualizing, manipulating, monitoring a biomolecular condensate and delivering one or more functional protein, label, drug or agent to a biomolecular condensate. |
| FILED | Friday, January 22, 2021 |
| APPL NO | 17/794724 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0071 (20130101) Original (OR) Class A61B 5/441 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 2500/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230061973 | XU et al. |
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| APPLICANT(S) | Larimar Therapeutics, Inc. (Bala Cynwyd, Pennsylvania); The United States of America, as Represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xin XU (Potomac, Maryland); Erik Johan Wagner (Sterling, Virginia); Bonita Rup (Boston, Massachusetts) |
| ABSTRACT | The present invention encompasses TAT peptide binding proteins. Specifically, the invention relates to antibodies that specifically bind to a TAT protein transduction domain. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. Methods of making and methods of using the antibodies of the invention for detection, quantification, purification and isolation of TAT protein transduction domain, e.g., a TAT fusion molecule comprising a TAT protein transduction domain, as well as methods of diagnosis and monitoring of HIV and AIDS are also provided herein. |
| FILED | Friday, February 05, 2021 |
| APPL NO | 17/796561 |
| CURRENT CPC | Peptides C07K 16/1072 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/31 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230062550 | Eksioglu |
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| APPLICANT(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida) |
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| INVENTOR(S) | Erika A. Eksioglu (Tampa, Florida) |
| ABSTRACT | Disclosed are modified DAP12 and methods of their use for enhancing immune responses and for treating cancer. |
| FILED | Wednesday, February 23, 2022 |
| APPL NO | 17/678565 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/15 (20130101) A61K 38/1709 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/4705 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 5/0639 (20130101) C12N 2501/998 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230062911 | Xiao |
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| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Shuo Xiao (Piscataway, New Jersey) |
| ABSTRACT | In one aspect, the present disclosure provides a method of treating, preventing, and/or ameliorating premature ovarian failure (POF) in a subject in need thereof, wherein the subject is a female cancer patient being administered at least one chemotherapeutic drug, the method comprising administering to the subject at least one c-Jun N-terminal Kinase (JNK) inhibitor. In certain embodiments, the JNK inhibitor is SP600125. In another aspect, the present disclosure provides a pharmaceutical composition comprising a JNK inhibitor. |
| FILED | Friday, September 02, 2022 |
| APPL NO | 17/901950 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/015 (20130101) A61K 38/22 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 15/08 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230063230 | England et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); ShangPharma Innovation Inc. (South San Francisco, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); ShangPharma Innovation Inc. (South San Francisco, California) |
| INVENTOR(S) | Pamela M. England (Pacifica, California); Matthew P. Jacobson (San Francisco, California); Richard Beresis (San Francisco, California) |
| ABSTRACT | Described herein, inter alia, are Nurr1 receptor modulators and uses thereof. In an aspect is provided a method for treating a disease associated with dysregulation and/or degeneration of dopaminergic neurons in the central nervous system of a subject in need thereof, the method including administering to the subject in need thereof a therapeutically effective amount of a compound described herein. |
| FILED | Wednesday, February 19, 2020 |
| APPL NO | 17/431111 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 67/03 (20130101) C07C 231/02 (20130101) C07C 231/12 (20130101) C07C 233/11 (20130101) C07C 233/22 (20130101) C07C 247/06 (20130101) C07C 303/22 (20130101) C07C 303/28 (20130101) C07C 303/38 (20130101) C07C 309/70 (20130101) C07C 311/06 (20130101) C07C 321/20 (20130101) Heterocyclic Compounds C07D 209/30 (20130101) C07D 217/02 (20130101) C07D 231/12 (20130101) C07D 249/04 (20130101) Original (OR) Class C07D 257/04 (20130101) C07D 265/32 (20130101) C07D 401/04 (20130101) C07D 403/04 (20130101) C07D 403/12 (20130101) C07D 409/04 (20130101) C07D 413/06 (20130101) C07D 413/12 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/027 (20130101) C07F 7/0812 (20130101) C07F 9/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230063427 | Igumenova et al. |
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| FUNDED BY |
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| APPLICANT(S) | Tatyana I. Igumenova (College Station, Texas); Sachin S. Katti (College Station, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tatyana I. Igumenova (College Station, Texas); Sachin S. Katti (College Station, Texas) |
| ABSTRACT | A crystallization method for making high-quality molecular crystals containing complexes of diacylglycerol (DAG)-effector proteins and ligands thereof. For example, some of such crystals are of a quality sufficient for crystal-structure determination by X-ray crystallography with a spatial resolution of at least 3.0 Å or, in some cases, of about 1 Å. At least some embodiments of the crystallization method and of the molecular crystals produced thereby can beneficially be used, e.g., to provide high-resolution guides for the design and development of exogenous agonists of DAG-effector proteins of therapeutic interest. |
| FILED | Wednesday, August 31, 2022 |
| APPL NO | 17/900740 |
| CURRENT CPC | Peptides C07K 1/306 (20130101) Original (OR) Class Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/00 (20130101) C30B 29/58 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230063616 | Sarkar et al. |
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| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Casim A. Sarkar (Minneapolis, Minnesota); Samira M. Azarin (Minneapolis, Minnesota); Qiuge Zhang (Minneapolis, Minnesota) |
| ABSTRACT | The disclosure relates to a biosensor on the bacterial cell surface for sensing and responding to extracellular molecules. Related methods of using the bacterial cells to inducibly express a protein of interest and/or a bioactive RNA molecule in a subject are disclosed. Related methods of using the bacterial cells to inducibly express a protein of interest or to detect a target of interest in a sample are also disclosed. |
| FILED | Wednesday, August 10, 2022 |
| APPL NO | 17/818899 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0066 (20130101) Peptides C07K 14/245 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56911 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230063768 | Shokat et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kevan M. Shokat (San Francisco, California); Ziyang Zhang (San Francisco, California); William A. Weiss (San Francisco, California); QiWen Fan (San Francisco, California) |
| ABSTRACT | Described herein, inter alia, are immunophilin binding compounds and methods of heating CNS diseases, including co-administering outside the CNS of a subject an anti-CNS disease drug and a compound described herein. |
| FILED | Thursday, February 06, 2020 |
| APPL NO | 17/427039 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/444 (20130101) A61K 31/496 (20130101) A61K 31/506 (20130101) Original (OR) Class A61K 31/517 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230063827 | Speicher et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Wistar Institute of Anatomy and Biology (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David W. Speicher (Berwyn, Pennsylvania); Hsin Yao Tang (Media, Pennsylvania); Lynn A. Beer (Medford, New Jersey) |
| ABSTRACT | A diagnostic reagent or device comprises at least one ligand capable of specifically complexing with, binding to, or quantitatively detecting or identifying the biomarker chloride intracellular channel protein 4 (CLIC4) or an isoform, pro-form, modified molecular form including posttranslational modification, or unique peptide fragment or nucleic acid fragment thereof. An alternative diagnostic reagent or device comprises ligand or ligands capable of specifically complexing with, binding to, or quantitatively detecting or identifying multiple tropomyosin biomarkers. Optionally, such reagent or device includes a signaling molecule and/or a substrate on which the ligand is immobilized. Other reagents and methods of diagnosing ovarian cancer include use of CLIC4 ligands and/or multiple tropomyosin ligands with an additional ovarian cancer biomarker. For example, CLIC4 combined with one or more of CLIC1 and/or one or multiple members of the tropomyosin family, e.g., TPM1, TPM2, TPM3 or TPM4, and further optionally including CTSD-30 kDa and/or PRDX-6, among other ovarian cancer biomarkers can form a characteristic diagnostic pattern or profile of expression that is diagnostic of the disease. Still other embodiments are described. |
| FILED | Tuesday, July 12, 2022 |
| APPL NO | 17/812060 |
| CURRENT CPC | Peptides C07K 16/3069 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6887 (20130101) G01N 33/57449 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230064064 | CHAN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF NORTH TEXAS (Dallas, Texas); The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Clement T. Y. CHAN (DALLAS, Texas); Faruck MORCOS (Austin, Texas); Xian-Li JIANG (Austin, Texas) |
| ABSTRACT | A method can include receiving a protein sequence (S) of a hybrid repressor, determining an original compatibility score C(S), where the compatibility score C is a function of the protein sequence (S) and predicting, based on the compatibility score C, a performance of the hybrid repressor. The hybrid protein sequence includes a plurality of DNA-binding modules (DBMs) and a plurality of ligand-binding modules (LBMs). |
| FILED | Wednesday, August 31, 2022 |
| APPL NO | 17/823921 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/635 (20130101) Original (OR) Class Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/30 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230064246 | MANTZOROS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christos MANTZOROS (Boston, Massachusetts); Nikolaos PERAKAKIS (Boston, Massachusetts); Alireza YAZDANI (New York, New York) |
| ABSTRACT | The disclosure features non-invasive methods for diagnosing non-alcoholic fatty liver (NAFL), non-alcoholic steatohepatitis (NASH), and liver fibrosis in a subject by, e.g., determining the level of one or more lipids, glycans, hormones, and/or fatty acids in a biological sample (e.g., a blood, serum, or plasma sample) obtained from the subject. Also described are methods of treating, monitoring, or evaluating the efficacy of a treatment for NAFL, NASH, or liver fibrosis in a subject based on the level of one or more lipids, glycans, hormones, and/or fatty acids in a biological sample (e.g., a blood, serum, or plasma sample) obtained from the subject. |
| FILED | Thursday, November 05, 2020 |
| APPL NO | 17/774338 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) Original (OR) Class G01N 33/743 (20130101) G01N 2800/52 (20130101) G01N 2800/085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230064249 | Denu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John Matthew Denu (Madison, Wisconsin); Weiping Tang (Madison, Wisconsin) |
| ABSTRACT | The present disclosure provides compounds according to Formula I and pharmaceutically acceptable salts thereof, as well as compositions including such compounds and a pharmaceutically acceptable carrier or excipient. Further provided are methods of inactivating SIRT6 with compounds of Formula I as well as compounds of Formula III, W2—R2—Y—R3, as described herein. In addition, the present technology provides methods of treatment using such compounds to lower LDL levels, lower triglyceride levels, and/or increase glucose tolerance in a subject, and/or to inhibit proliferation of ovarian, colorectal, hepatocellular, non-small cell lung, glioblastoma, osteosarcoma, pancreatic, and skin cancer cells, and/or inhibit liver and/or kidney fibrosis, and/or promote corneal epithelial wound healing. |
| FILED | Friday, December 04, 2020 |
| APPL NO | 17/782577 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4035 (20130101) Original (OR) Class Heterocyclic Compounds C07D 209/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230064292 | Langton-Webster et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cancer Targeted Technology LLC (Woodinville, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Beatrice Langton-Webster (Woodinville, Washington); Hillarie P. Windish (Woodinville, Washington) |
| ABSTRACT | The invention relates to methods of treating cancer with CTT1403 having specificity for prostate-specific membrane antigen (PSMA). |
| FILED | Friday, January 29, 2021 |
| APPL NO | 17/759754 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/088 (20130101) A61K 51/0497 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230064428 | Price |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Koska Family Limited (East Sussex, United Kingdom) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeff Price (Windermere, Florida) |
| ABSTRACT | A pre-filled medical delivery system can have a blow-fill-seal (BFS) component and a connection assembly. The BFS component can have first and second chambers, and first and second sealed ports. Each chamber can have a respective liquid agent therein. Each sealed port can be in fluid communication with a respective one of the chambers. The connection assembly can be constructed for coupling to the BFS component. When coupled to the BFS component, the connection assembly can breach the seals of the first and second ports and provide fluid communication therebetween. The disclosed systems, when assembled, can combine the liquid agents from the first and second chambers of the BFS component and deliver the combination as a single dose of a therapeutic agent (e.g., vaccine, drug, medicament, etc.) to a patient. |
| FILED | Monday, November 07, 2022 |
| APPL NO | 17/982396 |
| CURRENT CPC | Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 1/20 (20130101) Original (OR) Class A61J 1/2013 (20150501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230064644 | Deisseroth et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Karl A. Deisseroth (Stanford, California); Charu Ramakrishnan (San Jose, California); Yoon Seok Kim (Stanford, California); Lief E. Fenno (Palo Alto, California) |
| ABSTRACT | The present disclosure provides recombinant expression vectors for modulating production of polypeptides of interest in a target cell or target cell population. Aspects of the disclosure include recombinant expression vectors having coding sequences encoding portions of a polypeptide of interest, where the coding sequences are flanked by recombinase recognition sites. Also provided are methods for using the recombinant expression vectors as well as a device for monitoring expression of the polypeptide of interest. |
| FILED | Wednesday, February 03, 2021 |
| APPL NO | 17/796839 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/66 (20130101) C12N 15/85 (20130101) Original (OR) Class C12N 2800/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230064792 | Rege |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VASOPTIC MEDICAL INC. (Columbia, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Abhishek Rege (Columbia, Maryland) |
| ABSTRACT | Imaging various regions of the eye is important for both clinical diagnostic and treatment purposes as well as for scientific research. Diagnosis of a number of clinical conditions relies on imaging of the various tissues of the eye. The subject technology describes a method and apparatus for imaging the eye using off-center illumination in a manner that avoids light striking the anterior surfaces of the eye at or near a center of the optical axis, thereby reducing reflections traveling back along an imaging light path, while also providing substantially uniform illumination of a region of interest of the fundus. |
| FILED | Friday, September 09, 2022 |
| APPL NO | 17/941348 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/12 (20130101) Original (OR) Class A61B 3/0025 (20130101) A61B 3/152 (20130101) A61B 3/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230064864 | Gittis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aryn Gittis (Pittsburgh, Pennsylvania); Teresa Anne Spix (Pittsburgh, Pennsylvania) |
| ABSTRACT | Provided herein is method of modulating a plurality of neurons in a patient, by stimulating an area of the patient's central nervous system. The stimulation includes alternating first periods when a plurality of pulses of electrical stimulation are delivered and second periods when no pulses of electrical stimulation are delivered. The first periods have a duration of about 100 to about 400 ms and the second periods have a duration of about 500 ms to about 1900 ms. The pulses have a frequency of about 100 Hz to about 250 Hz. |
| FILED | Friday, January 15, 2021 |
| APPL NO | 17/792919 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0534 (20130101) A61N 1/36067 (20130101) Original (OR) Class A61N 1/36171 (20130101) A61N 1/37514 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230065014 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gary Yu (Pittsburgh, Pennsylvania); Bruce A. Freeman (Pittsburgh, Pennsylvania); Flordeliza S. Villanueva (Pittsburgh, Pennsylvania); John J. Pacella (Bethel Park, Pennsylvania); Marco Fazzari (Pittsburgh, Pennsylvania); Xucai Chen (Pittsburgh, Pennsylvania); Thiruganesh Ramasamy (San Francisco, California) |
| ABSTRACT | Provided herein are microbubble compositions comprising nitro-fatty acids and/or esters thereof, such as amphiphilic esters or allyl esters thereof. Also provided are methods of reducing local inflammation at a site in a patient comprising delivering the microbubbles to a site of inflammation in the patient and applying ultrasound to the microbubbles. The methods may be used to treat fibrosis or cancer. |
| FILED | Thursday, January 14, 2021 |
| APPL NO | 17/792653 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5015 (20130101) Original (OR) Class A61K 31/19 (20130101) A61K 47/10 (20130101) A61K 47/24 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230065376 | DU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | New York Blood Center, Inc. (New York, New York); Loyola University of Chicago (Maywood, Israel) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lanying DU (New York, New York); Wanbo TAI (New York, New York); Liang QIAO (Maywood, Illinois); Frank GAMBINO (Maywood, Illinois) |
| ABSTRACT | Provided herein are immunogenic compositions for the prevention of Zika virus infections. Disclosed herein are immunogenic compositions comprising an expression vector and a nucleotide sequence disposed therein, wherein the nucleotide sequence comprises: a nucleotide sequence encoding a Zika virus NS3 protein. Further disclosed herein are methods for preventing a Zika virus infection in a subject in need thereof, the method comprising administering a therapeutically effective amount of an immunogenic composition of the present disclosure to the subject. |
| FILED | Thursday, February 04, 2021 |
| APPL NO | 17/797662 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/53 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230065505 | Silva et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan Silva (St. Louis, Missouri); Christopher Andrews (Chesterfield, Missouri); Jennifer Silva (St. Louis, Missouri); Zahid Iqbal (Kirkwood, Missouri) |
| ABSTRACT | A mixed reality (MR) visualization system includes an MR device comprising a holographic display configured to display a holographic image to an operator, a hand-held ultrasound imaging device configured to obtain a real-time ultrasound image of a subject's anatomy, and a computing device communicatively coupled to the MR device and the hand-held ultrasound imaging device. The computing device includes a non-volatile memory and a processor. The computing device is configured to receive the real-time ultrasound image, determine a real-time 3D position and orientation of the hand-held ultrasound imaging device, generate a modified real-time ultrasound image by modifying the real-time ultrasound image to correspond to the real-time 3D position and orientation of the hand-held ultrasound imaging device, and transmit the modified real-time ultrasound image to the MR device for display as the holographic image positioned at a predetermined location relative to the hand-held ultrasound imaging device. |
| FILED | Tuesday, April 13, 2021 |
| APPL NO | 17/799826 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/42 (20130101) Original (OR) Class A61B 8/4416 (20130101) A61B 34/20 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230065522 | KOSSATZ et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Susanne KOSSATZ (New York, New York); Thomas REINER (New York, New York); Wolfgang WEBER (New York, New York); Snehal G. PATEL (New York, New York) |
| ABSTRACT | The present disclosure describes methods of use of a composition comprising PARPi-fl to be administered to the oral cavity (e.g., via topical application to surfaces of the oral cavity) followed by imaging of the oral cavity for detection of squamous cell carcinoma of the oral cavity (e.g., in vivo, e.g., in a dental office setting or intraoperatively). The results disclosed herein show that topically applied PARPi-fl and subsequent intraoperative imaging of oral cavities can improve surgical removal of squamous cell carcinoma cells compared to healthy cells. |
| FILED | Wednesday, June 22, 2022 |
| APPL NO | 17/846690 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0036 (20180801) A61B 5/055 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 49/0021 (20130101) A61K 49/0052 (20130101) Original (OR) Class A61K 49/0071 (20130101) A61K 49/0073 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230065816 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Reasearch Foundation for Suny (Albany, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nai-Jiang Liu (Staten Island, New York); Alan Gintzler (Brooklyn, New York) |
| ABSTRACT | The current disclosure provides methods for treating chronic pain. The present methods reduce opioid analgesic/antiallodynic tolerance in a subject with chronic pain and prevent the development of opioid analgesic/antiallodynic tolerance. More specifically, the inventive methods include the administration of a caveolin-1 scaffolding domain competing polypeptide (CSD) and/or a non-receptor tyrosine kinase (c-Src) inhibitor to reduce opioid analgesic/antiallodynic tolerance as well as prevent the onset of opioid analgesic/antiallodynic tolerance in a subject with chronic pain. |
| FILED | Thursday, December 31, 2020 |
| APPL NO | 17/797208 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/485 (20130101) A61K 31/519 (20130101) A61K 38/177 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/36 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230065974 | Schmidt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Ehud J. Schmidt (Towson, Maryland); Yue Chen (Boston, Massachusetts); Akila Viswanathan (Baltimore, Maryland); Henry R. Halperin (Baltimore, Maryland); Junichi Tokuda (Boston, Massachusetts); Anthony Gunderman (Fayetteville, Arkansas) |
| ABSTRACT | Provided herein are methods of analyzing tissue using a magnetic resonance imaging (MRI) compatible tissue analysis device that includes radio¬frequency (RF) tracking and imaging elements. Related kits, systems, and computer program products are also provided. |
| FILED | Thursday, January 14, 2021 |
| APPL NO | 17/793144 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0036 (20180801) Original (OR) Class A61B 5/055 (20130101) A61B 34/20 (20160201) A61B 2034/2051 (20160201) A61B 2090/3958 (20160201) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/34 (20130101) G01R 33/287 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230066152 | Kleinstiver et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Benjamin Kleinstiver (Boston, Massachusetts); Russell T. Walton (Waban, Massachusetts) |
| ABSTRACT | The disclosure provides methods for the concurrent assessment of large numbers of genome engineering proteins, including CRISPR nucleases and base editors. Specifically, the disclosure provides methods of providing a plurality of individual discrete samples comprising populations of cells, wherein each population of cells overexpresses both (i) a single genome engineering protein or a variant thereof and (ii) a reporter protein, lysing the cells to release the proteins; normalizing levels of the genome engineering proteins or variants thereof; allowing the genome engineering proteins or variants thereof to combine with a guide RNA under conditions sufficient to form ribonucleoprotein complexes in each sample; contacting each sample with a plurality of analysis substrates, determining levels of each of the analysis substrate in each sample at a plurality of times; and calculating rate of depletion or enrichment of each of the analysis substrates from each sample. |
| FILED | Monday, January 25, 2021 |
| APPL NO | 17/794520 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/111 (20130101) C12N 15/1068 (20130101) Original (OR) Class C12N 15/1086 (20130101) C12N 2310/20 (20170501) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230066380 | Ichida et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Justin Ichida (Los Angeles, California); Gabriel Linares (Los Angeles, California) |
| ABSTRACT | Disclosed is a method of treating a subject who has a neurological disease. In one aspect, the method includes a step of administering an effective dose of a SYF2 antisense or inhibitory nucleic acid to a subject in need thereof, thereby restoring nuclear localization of TDP-43. |
| FILED | Friday, January 22, 2021 |
| APPL NO | 17/793554 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/33 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/323 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230066453 | Esquivel-Upshaw et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Josephine F. Esquivel-Upshaw (Gainesville, Florida); Arthur E. Clark (Newberry, Florida); Fan Ren (Gainesville, Florida); Samira Afonso Camargo (Gainesville, Florida) |
| ABSTRACT | In one aspect, the disclosure relates to protective, anti-bacterial coatings for medical implants and methods of making the same. Also disclosed herein are methods for improving the anti-bacterial properties of a medical device coated with silicon carbide (SiC) or titanium nitride (TiN). Further disclosed herein are medical devices including an anti-microbial layer prepared by the disclosed methods. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure. |
| FILED | Monday, January 04, 2021 |
| APPL NO | 17/759760 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/04 (20130101) A61L 27/10 (20130101) A61L 27/54 (20130101) A61L 27/306 (20130101) Original (OR) Class A61L 31/08 (20130101) A61L 2300/404 (20130101) A61L 2430/12 (20130101) A61L 2430/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230066585 | Swaroop et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Servic (Bethesda, Maryland) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Servic (Bethesda, Maryland) |
| INVENTOR(S) | Anand Swaroop (Bethesda, Maryland); Zhijian Wu (Bethesda, Maryland); Suja D. Hiriyanna (Bethesda, Maryland); Kamil Kruczek (Bethesda, Maryland) |
| ABSTRACT | Methods are disclosed for treating a cone rod homeobox transcription factor (CRX) autosomal dominant retinopathy in a subject. These methods include administering to the subject an effective amount of a nucleic acid molecule comprising a retinal specific promoter operably linked to a nucleic acid molecule encoding a CRX protein. Compositions are disclosed that include an effective amount of a nucleic acid molecule comprising a retinal specific promoter operably linked to a nucleic acid molecule encoding CRX, for use in treating a CRX autosomal dominant retinopathy in a subject. A retinal specific promoter is disclosed that includes the nucleotide sequence of SEQ ID NO: 1. |
| FILED | Friday, January 15, 2021 |
| APPL NO | 17/789729 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0041 (20130101) A61K 48/0058 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) Peptides C07K 14/4705 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) C12N 15/86 (20130101) C12N 2750/14143 (20130101) C12N 2830/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230066830 | FISHER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul B. FISHER (Richmond, Virginia); Sarmistha TALUKDAR (Richmond, Virginia); Swadesh K. DAS (Richmond, Virginia); Anjan PRADHAN (Richmond, Virginia); Luni EMDAD (Richmond, Virginia) |
| ABSTRACT | Provided herein are pharmaceutical compositions and methods useful for treating cancer and preventing cancer metastasis, particularly in cancers that have increased MDA-9/Syntenin expression. |
| FILED | Friday, December 18, 2020 |
| APPL NO | 17/787483 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/165 (20130101) A61K 31/167 (20130101) A61K 31/336 (20130101) A61K 31/337 (20130101) A61K 31/439 (20130101) A61K 31/519 (20130101) Original (OR) Class A61K 31/4353 (20130101) A61K 31/4406 (20130101) A61K 38/15 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2310/531 (20130101) C12N 2320/31 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230066882 | Baker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Coleman Baker (Galveston, Texas); Xuping Xie (Galveston, Texas); Pei-Yong Shi (Galveston, Texas) |
| ABSTRACT | Certain embodiments are directed to a stable recombinant flavivirus nucleic acid having a heterologous reporter cassette, the reporter cassette having a 5′ end, a nucleotide segment encoding a reporter, and a 3′ end; the 5′ end of the reporter cassette encoding 25 to 38 amino acids of a flavivirus capsid protein; the 3′ end of the reporter cassette encoding 25 to 38 amino acids of a flavivirus capsid protein. |
| FILED | Thursday, August 26, 2021 |
| APPL NO | 17/412900 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 9/0069 (20130101) C12N 2770/24121 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230067234 | Diamond et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Feinstein Institutes for Medical Research (Manhasset, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Betty A. Diamond (Bronx, New York); Simone Mader (Woodside, New York); Lior Brimberg (Bayside, New York); Peter Gregersen (Larchmont, New York) |
| ABSTRACT | Methods of diagnosis and methods of treatment and prevention for autism spectrum disorder are provided using decoy antigens to maternal brain-reactive antibodies. |
| FILED | Tuesday, June 21, 2022 |
| APPL NO | 17/845021 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/17 (20130101) A61K 38/177 (20130101) A61K 38/1709 (20130101) A61K 38/1774 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Peptides C07K 16/18 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 33/6896 (20130101) G01N 2800/28 (20130101) G01N 2800/38 (20130101) G01N 2800/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230067623 | Stahl et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shannon Stahl (Madison, Wisconsin); Jason Bates (Madison, Wisconsin) |
| ABSTRACT | A method of making an M-N—C catalyst is disclosed. The method includes the steps of (a) contacting an N-doped carbon support with a basic solution that includes a metal salt, whereby the N-doped carbon support is metalated by the metal cation of the metal salt to form one or more chelated metal-nitrogen complexes (MNx species); and (b) subsequently contacting the metalated N-doped carbon support with an acid, whereby the one or more MNx species formed on the N-doped carbon support in step (a) remain intact while other species are removed. The resulting composition may be catalytically activated by heat treating the composition. The activated catalyst may be used to catalyze a wide range of chemical reactions. |
| FILED | Wednesday, August 10, 2022 |
| APPL NO | 17/885205 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/18 (20130101) B01J 31/1691 (20130101) Original (OR) Class B01J 37/08 (20130101) B01J 37/0203 (20130101) B01J 37/0205 (20130101) B01J 37/0209 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 11/075 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230067643 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Miqin Zhang (Seattle, Washington); Qingxin Mu (Seattle, Washington); Guanyou Lin (Seattle, Washington) |
| ABSTRACT | Multifunctional nanoparticle for targeted therapeutic drug delivery, comprising (a) an iron oxide core having silica-polyethylene glycol coupled thereto to provide an iron oxide coated core, (b) a cytotoxic agent reversibly associated with the coated core; (c) an immunomodulating agent reversibly associate with the coated core; and (d) a tumor targeting agent associated with the coated core. Methods for using the nanoparticle to treat cancers and methods for making the nanoparticle. |
| FILED | Tuesday, August 23, 2022 |
| APPL NO | 17/821794 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/60 (20170801) A61K 47/6923 (20170801) A61K 47/6929 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230067811 | Kipnis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan Kipnis (Charlottesville, Virginia); Antoine Louveau (Charlottesville, Virginia); Sandro Da Mesquita (Charlottesville, Virginia) |
| ABSTRACT | In some embodiments herein, methods, compositions, and uses for modulating lymphatic vessels of the central nervous system are described. In some embodiments, methods, compositions, or uses for treating, preventing, or ameliorating symptoms of a neurological disease comprise increasing flow via meningeal lymphatic vessels are described. |
| FILED | Monday, January 25, 2021 |
| APPL NO | 17/794338 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1825 (20130101) Original (OR) Class A61K 38/1866 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230067926 | Major et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Terry Major (Ann Arbor, Michigan); Deokwon Seo (Ann Arbor, Michigan); Jinsang Kim (Ann Arbor, Michigan) |
| ABSTRACT | Provided herein are compositions, systems, and methods for monitoring platelet activation. In particular, provided herein are sensor devices for measuring platelet activation and uses thereof. |
| FILED | Tuesday, July 19, 2022 |
| APPL NO | 17/868422 |
| CURRENT CPC | Peptides C07K 16/18 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/86 (20130101) Original (OR) Class G01N 2333/75 (20130101) G01N 2800/224 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230067927 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xinyue Zhang (Stanford, California); Michael P. Snyder (Stanford, California) |
| ABSTRACT | A collector device of environmental exposure is provided. This device may be used to collect and, after technical upgrade, monitor environmental exposure in personal and stationary settings. By coupling with advanced genomic analysis and chemical analysis technologies, the device and its accompanying methodology are capable of detecting environmental agents of diverse nature, many of which could pose health risks if going unaware of or uncontrolled. This type of information provides much needed clues to reconstruct and pinpoint the course of disease etiology at both personal and epidemic scales. By combining personal exposome and personal omics analyses, we can recapitulate with the intention to then prescribe treatment plans with unprecedented precision. |
| FILED | Monday, October 31, 2022 |
| APPL NO | 17/977393 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/701 (20130101) C12Q 1/6806 (20130101) C12Q 1/6888 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/14 (20130101) G01N 1/34 (20130101) Original (OR) Class G01N 15/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230068056 | Beebe et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Beebe (Monona, Wisconsin); Duane Juang (Madison, Wisconsin); Terry Juang (Madison, Wisconsin) |
| ABSTRACT | A sample extraction cassette and method are provided to test for a target in a sample. The sample is obtained on a swab. The swab is inserted into a chamber in a case and into contact with a contact portion of a membrane. The contact portion of the membrane is axially moved into sequential communication with a wash fluid and a reaction fluid. The reaction fluid reacts with the target to provide a visual display corresponding to the presence of the target. |
| FILED | Monday, August 30, 2021 |
| APPL NO | 17/461326 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5029 (20130101) Original (OR) Class B01L 2200/16 (20130101) B01L 2200/141 (20130101) B01L 2200/0636 (20130101) B01L 2300/069 (20130101) B01L 2300/161 (20130101) B01L 2300/0829 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230068456 | Opina et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ana Christina Opina (Gaithersburg, Maryland); Murali Krishna Cherukuri (Potomac, Maryland); Rolf Eric Swenson (Silver Spring, Maryland); Kazutoshi Yamamoto (North Bethesda, Maryland); Deepak Sail (Potomac, Maryland) |
| ABSTRACT | A method of diagnosing or monitoring a patient suffering from cancer, the method comprising: administering a pharmaceutical composition comprising an effective amount of an active agent, wherein the active agent is [1-13C] N-acetyl cysteine, a deuterated derivative thereof, a pharmaceutically acceptable salt of any of the foregoing thereof, or a combination thereof, together with a pharmaceutically acceptable carrier to the patient; and diagnosing or monitoring the patient by hyperpolarized 13C-MRI. Also disclosed is a method of synthesizing [1-13C] N-acetyl cysteine or a deuterated derivative thereof. |
| FILED | Friday, January 15, 2021 |
| APPL NO | 17/793083 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 49/10 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230068698 | Karin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Karin (La Jolla, California); Hua Su (La Jolla, California) |
| ABSTRACT | Provided herein are methods and compositions for treating cancer through a combination of an inhibitor of macropinocytosis upregulation and an autophagy inhibitor. Also provided are methods and compositions for inducing cell death of cancer cells, and transgenic animal models regarding same. |
| FILED | Wednesday, January 13, 2021 |
| APPL NO | 17/792387 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/137 (20130101) A61K 31/366 (20130101) A61K 31/427 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230068750 | Lou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee) |
| ASSIGNEE(S) | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee) |
| INVENTOR(S) | Jinchao Lou (Knoxville, Tennessee); Jennifer Schuster (Knoxville, Tennessee); Francisco Nicolas Barrera Olivares (Knoxville, Tennessee); Michael Douglas Best (Knoxville, Tennessee) |
| ABSTRACT | Dimer and monomer molecules according to general formulas (I) or (II) are useful as lipid switch molecules when incorporated into a membrane of a liposome. wherein R1 is a hydrophobic tail having at least 6 carbons and wherein R2 is selected from the group consisting of —NH2, wherein, for the dimer, the linker is a saturated carbon chain having 2 to 6 carbons or is a para-xylene linker; and when R2 is charged anions are present to render the charge neutral. These molecules can bind ATP or similar small phosphorylated molecules between R2 groups, which changes the shape of the molecule or the molecules orientation within the membrane thereby acting as a “switch” to release a therapeutic agent from the liposome. |
| FILED | Monday, August 01, 2022 |
| APPL NO | 17/878467 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1273 (20130101) A61K 9/1277 (20130101) A61K 31/704 (20130101) A61K 47/58 (20170801) A61K 47/6925 (20170801) Original (OR) Class A61K 47/6935 (20170801) A61K 49/0084 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/88 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230068856 | Machielse et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mandos LLC (West Hollywood, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bernardus Nicolaas Machielse (North Potomac, Maryland); Allan Darling (North Potomac, Maryland) |
| ABSTRACT | This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C. |
| FILED | Thursday, October 20, 2022 |
| APPL NO | 17/970080 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/0019 (20130101) A61K 9/0085 (20130101) A61K 31/724 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230068887 | SOUTHERLAND et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Meharry Medical College (Nashville, Tennessee) |
| ASSIGNEE(S) | Meharry Medical College (Nashville, Tennessee) |
| INVENTOR(S) | Janet H. SOUTHERLAND (Nashville, Tennessee); Pandu R. GANGULA (Nashville, Tennessee) |
| ABSTRACT | Pharmaceutical compositions and methods of treatment or prevention of diseases and conditions associated with or characterized by at least one of xerostomia and periodontal disease by modulation of the nitric oxide synthase pathway are provided, as are animal models and drug screening methods. Such modulation may be achieved by the administration of tetrahydrobiopterin (BH4) or its prodrugs and/or salts. Treating and preventing xerostomia can have the downstream effect of also preventing periodontitis, dental caries, parotid gland enlargement, inflammation and fissuring of the lips (chelitis), inflammation or ulcers of the tongue and buccal mucosa, oral candidiasis, salivary gland infection (sialadenitis), halitosis, and cracking and fissuring of oral mucosa. |
| FILED | Monday, September 19, 2022 |
| APPL NO | 17/948184 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/10 (20130101) A61K 9/0056 (20130101) A61K 9/0058 (20130101) A61K 9/0063 (20130101) A61K 31/519 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/02 (20180101) A61P 5/48 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230068989 | Zeng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of South Carolina (Columbia, South Carolina) |
| ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
| INVENTOR(S) | Qiang Zeng (West Columbia, South Carolina); Lannan Luo (West Columbia, South Carolina) |
| ABSTRACT | Described herein are methods, techniques and systems for a user to conduct authentication via inertial measurement unit data collected by the user's smartphone and video data collected by a drone recording the user operations for mutual authentication, as well as to prevent attacks of the authentication data, wherein correlation can be easily extended to using other information, such as noises, illuminance, GPS, and how the phone flashlight flashes. |
| FILED | Thursday, June 30, 2022 |
| APPL NO | 17/854060 |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0832 (20130101) Wireless Communication Networks H04W 12/06 (20130101) Original (OR) Class H04W 12/0431 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230068990 | Zheng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Platefuse, Inc. (Cincinnati, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yi Zheng (Cincinnati, Ohio); Jose Cancelas (Cincinnati, Ohio) |
| ABSTRACT | Disclosed are compounds and compositions for slowing, preventing, or reversing platelet damage, particularly as may occur during blood banking or during refrigeration of platelets. Also disclosed herein are methods for storing platelets and methods for improving platelet survival upon transfusion with one or more compounds or compositions as described herein. |
| FILED | Wednesday, January 13, 2021 |
| APPL NO | 17/792864 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0226 (20130101) Original (OR) Class A01N 1/0284 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0644 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230069100 | Appella et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Daniel H. Appella (Rockville, Maryland); Herman Nikolayevskiy (Sausalito, California); Marco Robello (Washington, District of Columbia); Michael T. Scerba (Baltimore, Maryland) |
| ABSTRACT | Disclosed is a compound of formula (I): for treating or preventing a human immunodeficiency virus (HIV) infection in a mammal, for inhibiting or preventing maturation of an immature human immunodeficiency virus (HIV) to a mature HIV, and for preventing or inhibiting a human immunodeficiency virus (HIV) infection in a mammal having at least one HIV viral particle on a surface thereof. |
| FILED | Thursday, December 17, 2020 |
| APPL NO | 17/785155 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) A61K 31/52 (20130101) A61K 31/427 (20130101) A61K 31/513 (20130101) A61K 31/635 (20130101) A61K 31/675 (20130101) A61K 31/4164 (20130101) Original (OR) Class A61K 31/5365 (20130101) A61K 39/21 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) Heterocyclic Compounds C07D 233/92 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230069622 | KOLESNICK et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Memorial Sloan-Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard KOLESNICK (New York, New York); Adriana HAIMOVITZ-FRIEDMAN (New York, New York); Evis SALA (New York, New York); Zvi FUKS (New York, New York) |
| ABSTRACT | Disclosed is a method for enhancing tumor response to chemotherapy, the method comprising administering a short-acting anti-angiogenic agent (AAA) capable of activating ASMase to a subject afflicted with a solid tumor, and thereby creating a time interval of increased susceptibility of said tumor to one or more chemotherapeutic agents, followed by administration of at least one chemotherapeutic agent within the interval. The interval can be defined in terms of a short-duration activation of ASMase signaling by the AAA. Disclosed are also methods for predicting the tumor response in a patient afflicted with a solid tumor to a chemotherapeutic agent, using as an indicator of the response ASMase level or activity (or ceramide level) in the patient following the administration of the chemotherapeutic agent to the patient, or dynamic IVIM based DW-MRI to measure perfusion alterations following administration of the chemotherapeutic agent. |
| FILED | Monday, March 28, 2022 |
| APPL NO | 17/705798 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 31/404 (20130101) A61K 31/4439 (20130101) Original (OR) Class A61K 31/7048 (20130101) A61K 31/7068 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57488 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230069723 | Frederich et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James H. Frederich (Tallahassee, Florida); James A. Law (Tallahassee, Florida) |
| ABSTRACT | Methods of hydromethylation of alkenes and ketones, including methods that use Tebbe's reagent. The methods may include contacting Cp2Ti(μ-Cl)(μ-CH2)AlMe2 and an alkene or a ketone to produce an intermediate product that may include a titanacyclobutane. The intermediate product may be contacted with an acid to produce a methylated product. |
| FILED | Monday, July 26, 2021 |
| APPL NO | 17/385528 |
| CURRENT CPC | Heterocyclic Compounds C07D 211/96 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230069820 | Harrison et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David G. Harrison (Nashville, Tennessee); David M. Patrick (Nashville, Tennessee) |
| ABSTRACT | The invention relates to compounds, compositions, and methods for the treatment of lupus. The compounds of the present invention are isoLG savaging compounds. |
| FILED | Thursday, September 24, 2020 |
| APPL NO | 17/031642 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/137 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20230060357 | Hart et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SolAero Technologies Corp. (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John Hart (Albuquerque, New Mexico); Daniel Derkacs (Albuquerque, New Mexico); Zachary Bittner (Albuquerque, New Mexico); Andrew Espenlaub (Albuquerque, New Mexico) |
| ABSTRACT | A multijunction solar cell including an upper first solar subcell having a first band gap and positioned for receiving an incoming light beam; a second solar subcell disposed below and adjacent to and lattice matched with said upper first solar subcell, and having a second band gap smaller than said first band gap; wherein at least one of the solar subcells has a graded band gap throughout the thickness of at least a portion of the active layer. |
| FILED | Tuesday, September 06, 2022 |
| APPL NO | 17/930022 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/065 (20130101) H01L 31/0687 (20130101) H01L 31/0693 (20130101) H01L 31/0725 (20130101) H01L 31/0735 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230060414 | Ahmed et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Temple University-Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania); Government of the United States, as represented by the secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Ammar Ahmed (Philadelphia, Pennsylvania); Yimin Daniel Zhang (Berwyn, Pennsylvania); Braham Himed (Beavercreek, Ohio) |
| ABSTRACT | A system for distributed dual-function radar-communication comprises a plurality of dual-function radar transmitters positioned within a region of interest, each configured to transmit at least one radar waveform, with each transmitter for having a minimum transmit power, a maximum transmit power, and a working transmit power, a plurality of radar receivers positioned within the region of interest, each configured to receive the radar waveforms, at least one controller communicatively connected to at least one connected transmitter of the plurality of dual-function radar transmitters, configured to calculate a vector of transmit power values for the plurality of dual-function radar transmitters. A method of transmitting a radar waveform is also disclosed. |
| FILED | Tuesday, April 21, 2020 |
| APPL NO | 16/854251 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4013 (20210501) Original (OR) Class Coding; Decoding; Code Conversion in General H03M 13/2906 (20130101) Wireless Communication Networks H04W 12/03 (20210101) H04W 64/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230060417 | SHREVE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Matthew A. SHREVE (Webster, New York); Eric COCKER (Redwood City, California) |
| ABSTRACT | The present specification relates to image capture. More specifically, it relates to selective image capture for sensor carrying devices or floats deployed, for example, on the open sea. In one form, data is generated on the sensor carrying devices or floats by an on-board Inertial Measurement Unit (IMU) and is used to automatically predict the wave motion of the sea. These predictions are then used to determine an acceptable set of motion parameters that are used to trigger the on-board camera(s). The camera(s) then capture images. One consideration is that images captured at or near the peak of a wave crest with minimal pitch and roll will contain fewer obstructions (such as other waves). Such images provide a view further into the horizon to, for example, monitor maritime sea traffic and other phenomenon. Therefore, the likelihood of capturing interesting objects such as ships, boats, garbage, birds, . . . etc. is increased. These images may then be further processed and/or transmitted in a variety of manners. |
| FILED | Tuesday, August 31, 2021 |
| APPL NO | 17/463433 |
| CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 79/15 (20200101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 13/004 (20130101) Pictorial Communication, e.g Television H04N 7/188 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230060597 | Caldwell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jesse T. Caldwell (Alpine, California); Brandon J. Wiedemeier (San Diego, California) |
| ABSTRACT | A flange for a pressure vessel includes a rim, a sealing seat, and an undercut fillet. The rim has an annular surface for abutting an annular end of a cylindrical wall of the pressure vessel. The sealing seat has a cylindrical surface for abutting an inner surface of the cylindrical wall of the pressure vessel nearby the annular end. The undercut fillet is disposed between the rim and the sealing seat. A concave surface of the undercut fillet extends the annular surface of the rim radially inward and then curves back outward to intersect the cylindrical surface of the sealing seat. The undercut fillet of the flange helps distribute stress produced from a pressure differential between the inside and outside of the pressure vessel. |
| FILED | Wednesday, August 25, 2021 |
| APPL NO | 17/411259 |
| CURRENT CPC | Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/001 (20130101) B63G 8/04 (20130101) Original (OR) Class B63G 2008/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230060648 | Cox |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Naval Information Warfare Center Pacific (San Diego, California) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (San Diego, California) |
| INVENTOR(S) | Stephen Charles Cox (San Diego, California) |
| ABSTRACT | A corrosion resistant bimetal includes a part and one or more sacrificial anodes. The part includes a metal component that is susceptible to corrosion. The sacrificial anodes consists of an attachment to the part through a metallic bond between the metal component and the sacrificial anode to form a crystalline solid that includes the sacrificial anode and the metal component of the part. |
| FILED | Wednesday, August 25, 2021 |
| APPL NO | 17/411342 |
| CURRENT CPC | Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 13/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230060666 | SMITH et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARM LIMITED (Cambridge, Cambridgeshire, United Kingdom) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bradley John SMITH (Cambridge, Cambridgeshire, United Kingdom); Thomas Christopher GROCUTT (Cambridge, Cambridgeshire, United Kingdom); François Christopher Jacques BOTMAN (Cambridge, Cambridgeshire, United Kingdom) |
| ABSTRACT | Apparatus comprises a processor to execute program instructions stored at respective memory addresses, processing of the program instructions being constrained by a prevailing capability defining at least access permissions to a set of one or more memory addresses; the processor comprising: control flow change handling circuitry to perform a control flow change operation, the control flow change operation defining a control flow change target address indicating the address of a program instruction for execution after the control flow change operation; and capability generating circuitry to determine, in dependence on the control flow change target address, an address at which capability access permissions data is stored; the capability generating circuitry being configured to retrieve the capability access permissions data and to generate a capability for use as a next prevailing capability in dependence upon at least the capability access permissions data. |
| FILED | Wednesday, December 02, 2020 |
| APPL NO | 17/759973 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/35 (20130101) G06F 9/3005 (20130101) G06F 12/1458 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230060791 | Alberti et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| INVENTOR(S) | Giuseppe S. Alberti (Shelton, Connecticut); Adriano Cirioli (North Haven, Connecticut); Sean Thomas Barrows (Stratford, Connecticut); Nolan John Birtwell (Southbury, Connecticut); Michael Alexander (Bridgeport, Connecticut); Nicholas Scott Coury (Shelton, Connecticut) |
| ABSTRACT | An aircraft includes an airframe defining a first enclosed space, an engine bay disposed within the first enclosed space, and a cooling system. The engine bay includes a firebox defining a second enclosed space and an engine disposed at least partially within the second enclosed space. The cooling system is configured to selectively fluidly couple the first enclosed space with the second enclosed space. |
| FILED | Wednesday, September 01, 2021 |
| APPL NO | 17/464532 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 1/10 (20130101) B64C 1/16 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 25/00 (20130101) Original (OR) Class B64D 33/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230061046 | Lim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (MINNEAPOLIS, Minnesota) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (MINNEAPOLIS, Minnesota) |
| INVENTOR(S) | Hubert Lim (Minneapolis, Minnesota); Daniel Zachs (Minneapolis, Minnesota); Claire Kaiser (Minneapolis, Minnesota); Rachel Graham (Minneapolis, Minnesota) |
| ABSTRACT | Systems and methods are provided for ultrasound stimulation for immunomodulation treatment. Ultrasound stimulation of the spleen may be used to alter immune and thereby inflammatory responses of a subject by modulating specific biomarkers or cytokines associated with inflammation. A closed-loop or responsive ultrasound stimulation of the spleen may be implemented by tracking biomarkers in the blood that indicate when the stimulation is working. Modulation of specific cytokines and/or erythrocyte sedimentation rate may be performed in response to ultrasound stimulation in a diseased state. |
| FILED | Friday, January 22, 2021 |
| APPL NO | 17/794098 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/416 (20130101) A61B 5/4836 (20130101) A61B 5/14503 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) Original (OR) Class A61N 2007/0078 (20130101) A61N 2007/0086 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/63 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230061881 | Barnwell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nathan Scott Barnwell (San Diego, California); Carlos Manuel Torres, JR. (San Diego, California); Burton H. Neuner, III (Escondido, California) |
| ABSTRACT | A measurement device characterizes an environment. The measurement device includes a transmitter and a receiver. The transmitter transmits a transmitted light. The transmitter includes an atomically two-dimensional material for emitting the transmitted light. The atomically two-dimensional material is tunable to select a predominate wavelength of the transmitted light within a tunable range of wavelengths. The receiver receives a received light, which is the transmitted light after encountering the environment. The receiver characterizes the environment from a measured change between the received light and the transmitted light. |
| FILED | Wednesday, August 25, 2021 |
| APPL NO | 17/411778 |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/12 (20130101) Original (OR) Class G01J 3/0297 (20130101) G01J 2003/1269 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230061961 | HUI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (, None) |
| INVENTOR(S) | Leo H. HUI (Alhambra, California); Haig Francis KRIKORIAN (Fullerton, California) |
| ABSTRACT | Agent/client pairs in at least one priority tier are determined. A matrix value is determined for each agent/client pair based on the client rank of the agent/client pair. An engagement capability parameter is determined for each agent/client pair. The matrix value for each disallowed agent/ranked client value is set to a zero value. All possible engagement options are evaluated. Candidate pair paths are determined by determining pair paths having a highest initial path value. The initial path value of each candidate pair path is decreased based on agent/client pairs in the candidate pair path that are urgent agent/client pairs or risky agent/client pairs to derive a final path value for each candidate pair path. A best path is determined based on the final path value for each candidate pair path. At least one engagement decision is derived based on the best path and transmitted towards agents in the best path. |
| FILED | Tuesday, June 22, 2021 |
| APPL NO | 17/354359 |
| CURRENT CPC | Electric Digital Data Processing G06F 17/16 (20130101) Computer Systems Based on Specific Computational Models G06N 5/043 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/06315 (20130101) G06Q 10/063112 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230062419 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nien-Hwa Linda Wang (West Lafayette, Indiana); David Harvey (West Lafayette, Indiana); Yi Ding (West Lafayette, Indiana) |
| ABSTRACT | A method for separating substantially pure rare earth metals and other metals from a mixed source, including putting a plurality of rare earth metals and other metals into solution to define a solution containing a plurality of respective metal ions, in at least one chromatographic column, selectively capturing ions of each respective metal with a respective ligand to define a plurality of respective discrete bands, and respectively eluting captured ions of respective metal from each respective band of the at least one chromatographic column to yield a plurality of purified solutions, each respective purified solution having a high concentration of a respective metal. The bands may either be stationary with respect to the columns, or may move through the columns. |
| FILED | Thursday, January 28, 2021 |
| APPL NO | 17/797822 |
| CURRENT CPC | Separation B01D 15/422 (20130101) Original (OR) Class B01D 15/1864 (20130101) B01D 15/3828 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 3/24 (20130101) C22B 59/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230063618 | Burnett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Architecture Technology Corporation (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Benjamin L. Burnett (Prior Lake, Minnesota); Deborah K. Charan (Minneapolis, Minnesota); Ian J. McLinden (Minneapolis, Minnesota); Jordan C. Bonney (Bloomington, Minnesota) |
| ABSTRACT | This disclosure is directed to network optimization in a complex joint network for increasing the network utility of the complex joint network. A computing device in the complex joint network may receive a data flow via a complex joint network. The computing device may determine, based on a network template, a mission utility associated with the data flow and a traffic class associated with the data flow. The computing device may control one or more quality of service decisions based at least in part on the mission utility associated with the data flow and the traffic class associated with the data flow. |
| FILED | Tuesday, September 06, 2022 |
| APPL NO | 17/929926 |
| CURRENT CPC | Transmission H04B 7/0617 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 41/0816 (20130101) H04L 41/0843 (20130101) H04L 41/0886 (20130101) H04L 45/02 (20130101) H04L 47/762 (20130101) H04L 47/781 (20130101) H04L 47/2441 (20130101) Original (OR) Class Wireless Communication Networks H04W 16/28 (20130101) H04W 76/19 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230064088 | Sheehan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Matthew Michael Sheehan (Washington, District of Columbia) |
| ABSTRACT | Provided is an apparatus and method for radar calibration that utilizes external shielding structures to be constructed around the body frame of a system to manage external signature presence and block unwanted signal emissions and intrusions. The inventive structures can adapt to desired user requirements or to environmental change as needed. The variable shielding with isolating connectors to the body frame of the system allows for aerodynamic needs to be sustained due to the mesh design while also protecting against electromagnetic spectrum interference and electro-optical short wave and long wave infrared signature emissions. The shielding can also be formed to emit a known or desired radio frequency response based on geometric shapes in order to influence radar cross-section readings. Communication with external environment is completed through the use of the shielding as a series of antennas. |
| FILED | Wednesday, August 24, 2022 |
| APPL NO | 17/894689 |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 17/005 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230064216 | Bro et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mitchell Bro (Tucson, Arizona); John Tristan Elmer (Tucson, Arizona); Jarrod Salmon (Tucson, Arizona); William Straus (Tucson, Arizona) |
| ABSTRACT | An arbor press includes a limiter for limiting load and/or travel of a ram used to press on an object. The ram includes a pair of pieces, a shaft and a sleeve, which are capable of relative translation, modulated by the spring. The spring may be preloaded, and configured to prevent overloading of the object, by limiting the transmission of force through the ram. The ram may also be configured to limit travel of the ram. The arbor press may include gearing to translate rotational movement of a handle to translational movement of the ram. The gearing may include a rack that is part of or is coupled to the shaft, and a pinion that is connected to the handle. Parts of the arbor press may be enclosed in a housing, to contain debris from metal-to-metal sliding in the arbor press, facilitating use in clean rooms. |
| FILED | Thursday, September 02, 2021 |
| APPL NO | 17/464818 |
| CURRENT CPC | Presses in General B30B 1/04 (20130101) Original (OR) Class B30B 15/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230064628 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, a body Corporate (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kai Yu (Denver, Colorado); Xu He (Littleton, Colorado); Martin Dunn (Denver, Colorado); Arif Abdullah (Denver, Colorado) |
| ABSTRACT | A printer head for three-dimensional printing of a continuous fiber-reinforced thermoset composite may include a deposition syringe, a fiber housing, and a feeding tube. The deposition syringe may define a resin reservoir, an air chamber, and a first inlet port configured to deliver a first flow of air to the air chamber. The deposition syringe may include a syringe body and a piston. The syringe body may include an inlet section, a needle section, and a converging section disposed between the inlet section and the needle section. The fiber housing may define a fiber chamber and a second inlet port configured to deliver a second flow of air to the fiber chamber. The feeding tube may extend from the fiber chamber to the needle section and may be configured to receive the second flow of air therein and to guide a fiber from the fiber chamber to the needle section. |
| FILED | Wednesday, August 31, 2022 |
| APPL NO | 17/900856 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/165 (20170801) B29C 64/209 (20170801) Original (OR) Class B29C 64/227 (20170801) B29C 64/264 (20170801) B29C 64/336 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230064980 | HOWE |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HOWE INDUSTRIES LLC (SCOTTSDALE, Arizona) |
| ASSIGNEE(S) | HOWE INDUSTRIES LLC (SCOTTSDALE, Arizona) |
| INVENTOR(S) | Troy HOWE (Scottsdale, Arizona) |
| ABSTRACT | A thermoelectric cooler including a thermoelectric junction and a radiation source. The thermoelectric cooler includes n-type material, p-type material, and an electrical power source. The radiation source emits ionizing radiation that increases electrical conductivity of the n and p type materials. Also detailed is a method of using radiation to reach high coefficient of performance (COP) values with a thermoelectric cooler that includes providing a thermoelectric cooler and a radiation source, with the thermoelectric cooler including an n-type material, p-type material, an electrical power source, and emitting ionizing radiation with the radiation source to increase the electrical conductivity which strips electrons from the n-type material, the p-type material, or both the n-type material and p-type material from their nuclei with the electrons then free to move within the material. |
| FILED | Thursday, October 13, 2022 |
| APPL NO | 18/046199 |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/16 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/26 (20130101) H01L 35/30 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230065024 | BOHMANN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Southwest Research Institute (San Antonio, Texas); The Government of The United States, as represented by The Secretary of the Army (Fort Detrick, Maryland); The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan A. BOHMANN (San Antonio, Texas); Nadean M. GUTIERREZ (Devine, Texas); Joseph A. MCDONOUGH (Helotes, Texas); Robert Francis CAMPBELL (Edgemere, Maryland); Michael Gordon JOYCE (Silver Spring, Maryland); Rekha PANCHAL (Fort Detrick, Maryland); Rajeshwer SANKHALA (Bethesda, Maryland); Allen DUPLANTIER (Stafford, Virginia) |
| ABSTRACT | Inhibitors against SARS-COV-1, SARS-CoV-2 (Covid-19), MERS-CoV, and variants within each, including methods of treating a subject suffering from such respiratory disease. |
| FILED | Friday, August 12, 2022 |
| APPL NO | 17/819524 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/427 (20130101) A61K 31/517 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230065235 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brewer Science, Inc. (Rolla, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zun Chen (Springfield, Missouri); Christopher Landorf (Springfield, Missouri); Vijaya Kayastha (Springfield, Missouri) |
| ABSTRACT | A carbon nanotube sensor device for detecting CO2 and methods of its production and use. A printable polyethylenimine (PEI)-functionalized carbon nanomaterial paste may be used to form the active sensing layer of the device, which is particularly sensitive to CO2. A separate printed heating layer may be used to maintain the working temperature of the sensor, as well as to remove and/or clear volatile gases from the sensor. |
| FILED | Monday, May 16, 2022 |
| APPL NO | 17/745375 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4146 (20130101) G01N 33/004 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230065377 | CROWE, JR. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | JAMES E. CROWE, JR. (Nashville, Tennessee) |
| ABSTRACT | The present disclosure is directed to antibodies binding to and neutralizing alphavirus, such as EEEV, WEEV or VEEV, and methods for use thereof. Thus, in accordance with the present disclosure, a method of detecting an alphavirus infection in a subject comprising (a) contacting a sample from said subject with an antibody or antibody fragment having clone-paired heavy and light chain CDR sequences from Tables 3 and 4, respectively; and (b) detecting alphavirus in said sample by binding of said antibody or antibody fragment to an alphavirus antigen in said sample. |
| FILED | Monday, August 31, 2020 |
| APPL NO | 17/638918 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/10 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230065398 | PURDY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The MITRE Corporation (McLean, Virginia) |
| ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
| INVENTOR(S) | Stephen F. PURDY (Springfield, Virginia); Steven E. NOEL (Woodbridge, Virginia); Edward A. OVERLY (Oak Hill, Virginia); Annie T. O'ROURKE (Red Bank, New Jersey) |
| ABSTRACT | Methods and systems are described for assessing a computer network using a graph model. In some instances, the methods comprise: receiving data from at least one data stream of a plurality of data streams, wherein the plurality of data streams comprise computer network data provided by one or more data brokers, and wherein the data received from different data streams of the plurality comprise different data formats; converting the data received from the at least one data stream to a common data format comprising a node or an edge; updating a graph model comprising a plurality of nodes and edges stored within a graph database according to the node or edge of the converted data; and providing a user of the computer network with a visualization of a status of the computer network. |
| FILED | Friday, August 27, 2021 |
| APPL NO | 17/459661 |
| CURRENT CPC | Electric Digital Data Processing G06F 11/328 (20130101) G06F 16/258 (20190101) G06F 16/9024 (20190101) G06F 16/24534 (20190101) G06F 16/24568 (20190101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1433 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230065658 | Fetter-Degges et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRX Systems, Inc. (Greenbelt, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan Fetter-Degges (Washington, District of Columbia); John Karvounis (Bowie, Maryland); Carole Teolis (Glendale, Maryland) |
| ABSTRACT | System, computer program products, and methods for detecting and compensating for sensor interference. Sensor interference may result from environmental interference or from electronic signal interference. Sensor location input may be adapted or rejected when interference is detected. The system can monitor the accuracy, as well as the integrity, of all navigation sensors. The system can also automatically eliminate the faulty or compromised data from a final navigation solution. |
| FILED | Wednesday, August 24, 2022 |
| APPL NO | 17/894660 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/08 (20130101) G01S 19/21 (20130101) Original (OR) Class G01S 19/37 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230066158 | PRICE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Erik PRICE (Cleveland, Ohio); Gary WNEK (Cleveland, Ohio); James COVELLO (Cleveland, Ohio) |
| ABSTRACT | An intumescent composition based upon modifications to tannic acid (TA), including certain additives, is contemplated. Such compositions may be incorporated in epoxy and other resin-based coatings. The resulting composition produces a novel, lightweight, and extremely effective intumescent char having a density of 1.5 to 4.0 mg/cm3. |
| FILED | Wednesday, August 17, 2022 |
| APPL NO | 17/889489 |
| CURRENT CPC | Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/185 (20130101) Original (OR) Class C09D 7/63 (20180101) C09D 163/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230066380 | Ichida et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Justin Ichida (Los Angeles, California); Gabriel Linares (Los Angeles, California) |
| ABSTRACT | Disclosed is a method of treating a subject who has a neurological disease. In one aspect, the method includes a step of administering an effective dose of a SYF2 antisense or inhibitory nucleic acid to a subject in need thereof, thereby restoring nuclear localization of TDP-43. |
| FILED | Friday, January 22, 2021 |
| APPL NO | 17/793554 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/33 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/323 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230066556 | HERRINGTON et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Voxel Innovations, Inc. (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel HERRINGTON (Raleigh, North Carolina); Eric ROUNTREE (Raleigh, North Carolina) |
| ABSTRACT | A discretized-flow electrode for use in electrochemical machining (ECM) and a corresponding method and system for using the discretized-flow cathode are disclosed. The machining face of the discretized-flow cathode is divided into a plurality of discrete sections. The discrete sections may be geometrically shaped, and they are separated at the machining face by an electrolyte flow outlet channel, and each discrete section includes an electrolyte flow inlet local to the discrete section. The plurality of discrete sections of the machining face of the discretized-flow electrode divide the electrolyte flow into approximately equal portions for even electrolyte flow across the machining face. |
| FILED | Thursday, October 20, 2022 |
| APPL NO | 18/048273 |
| CURRENT CPC | Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 5/08 (20130101) C25D 17/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230066557 | Wilker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Jonathan J. Wilker (West Lafayette, Indiana); Samuel L. Huntington (Greenville, South Carolina); Amelia A. Putnam (Mansfield, Georgia) |
| ABSTRACT | This invention relates to a method for manufacturing a catechol-containing co-polymer through a suspension polymerization or a solution polymerization process. In some illustrative embodiments, this disclosure relates to a process of a free radical suspension polymerization for large-scale manufacturing catechol-containing copolymers. In some other illustrative embodiments, this disclosure relates to a solution polymerization of free radical, cationic, or anionic process for large-scale manufacturing catechol-containing copolymers. The process and the product thereof are within the scope of this disclosure. |
| FILED | Thursday, December 17, 2020 |
| APPL NO | 17/787190 |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 212/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230067079 | ZHENG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Yu ZHENG (Stanford, California); Zhenan BAO (Stanford, California); Zhiao YU (Stanford, California) |
| ABSTRACT | Next-generation wearable electronics require enhanced mechanical robustness and device complexity. Besides previously reported softness and stretchability, desired merits for practical use include elasticity, solvent resistance, photo-patternability and high charge carrier mobility. The present embodiments provide a molecular design concept that simultaneously achieves all these targeted properties in both polymeric semiconductors and dielectrics, without compromising electrical performance. This is enabled by covalently-embedded in-situ rubber matrix (iRUM) formation through good mixing of iRUM precursors with polymer electronic materials, and finely-controlled composite film morphology built on azide crosslinking chemistry which leverages different reactivities with C—H and C═C bonds. The high covalent crosslinking density results in both superior elasticity and solvent resistance. When applied in stretchable transistors, the iRUM-semiconductor film retained its mobility after stretching to 100% strain, and exhibited record-high mobility retention of 1 cm2 V−1 s−1 after 1000 stretching-releasing cycles at 50% strain. The cycling life was stably extended to 5000 cycles, five times longer than all reported semiconductors. |
| FILED | Tuesday, August 30, 2022 |
| APPL NO | 17/899512 |
| CURRENT CPC | Compositions of Macromolecular Compounds C08L 9/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230067192 | LUNDBERG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The MITRE Corporation (McLean, Virginia) |
| ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
| INVENTOR(S) | Erik T. LUNDBERG (Cambridge, Massachusetts); Hugo F. TRAPPE (Medford, Massachusetts); Christian PD. MINOR (Bedford, Massachusetts); David LONG (Xenia, Ohio) |
| ABSTRACT | Examples in accordance with this disclosure provide a system for detecting a spoofed signal, the spoofed signal comprising position-navigation-timing (PNT) data. The system can include a first antenna and a second antenna, both configured to receive one or more first signals from one or more navigation satellites. The first antenna and second antenna can be configured to be separated by a first distance. The system can include a first receiver coupled to the first antenna and a second receiver coupled to the second antenna, where each antenna is configured to receive one or more signals from the respective antenna. Each of the first receiver and the second receiver are configured to extract a respective carrier phase data. |
| FILED | Thursday, August 26, 2021 |
| APPL NO | 17/412925 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/29 (20130101) G01S 19/215 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230067234 | Diamond et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Feinstein Institutes for Medical Research (Manhasset, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Betty A. Diamond (Bronx, New York); Simone Mader (Woodside, New York); Lior Brimberg (Bayside, New York); Peter Gregersen (Larchmont, New York) |
| ABSTRACT | Methods of diagnosis and methods of treatment and prevention for autism spectrum disorder are provided using decoy antigens to maternal brain-reactive antibodies. |
| FILED | Tuesday, June 21, 2022 |
| APPL NO | 17/845021 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/17 (20130101) A61K 38/177 (20130101) A61K 38/1709 (20130101) A61K 38/1774 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Peptides C07K 16/18 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 33/6896 (20130101) G01N 2800/28 (20130101) G01N 2800/38 (20130101) G01N 2800/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230067663 | Alabastri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Alessandro Alabastri (Houston, Texas); Pratiksha Dongare (Houston, Texas); Nancy J. Halas (Houston, Texas); Peter J. Nordlander (Houston, Texas); Oara Neumann (Houston, Texas) |
| ABSTRACT | A method includes providing a resonant thermal oscillator in a thermofluidic system having at least two counter-flowing liquid streams separated by at least a spectrum absorbing material, wherein the spectrum absorbing material is hydrophobic, light-absorbing, and photothermal, and adjusting a flow rate in at least one of the counter-flowing liquid streams to maximize heat transfer between the at least two counter-flowing liquid streams. |
| FILED | Friday, February 12, 2021 |
| APPL NO | 17/760070 |
| CURRENT CPC | Separation B01D 1/0035 (20130101) B01D 1/0041 (20130101) Original (OR) Class B01D 1/0082 (20130101) B01D 3/007 (20130101) B01D 61/364 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/008 (20130101) C02F 1/14 (20130101) C02F 1/043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230067936 | Welle |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Richard P. Welle (Huntington Beach, California) |
| ABSTRACT | An apparatus includes a satellite in the form of a plate having a thickness being smaller than a width of the satellite. The apparatus also includes a plurality of contact points distributed on a face of the satellite, allowing for one or more additional satellites to be stacked upon the satellite. |
| FILED | Wednesday, October 19, 2022 |
| APPL NO | 18/047994 |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/641 (20130101) Original (OR) Class B64G 1/1085 (20130101) B64G 2001/643 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230069266 | SMITH et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARM LIMITED (Cambridge, Cambridgeshire, United Kingdom) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bradley John SMITH (Cambridge, Cambridgeshire, United Kingdom); Thomas Christopher GROCUTT (Cambridge, Cambridgeshire, United Kingdom) |
| ABSTRACT | There is provided a data processing apparatus comprising a plurality of registers, each of the registers having data bits to store data and metadata bits to store metadata. Each of the registers is adapted to operate in a metadata mode in which the metadata bits and the data bits are valid, and a data mode in which the data bits are valid and the metadata bits are invalid. Mode bit storage circuitry indicates whether each of the registers is in the data mode or the metadata mode. Execution circuitry is responsive to a memory operation that is a store operation on one or more given registers. |
| FILED | Thursday, November 26, 2020 |
| APPL NO | 17/759978 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/30123 (20130101) Original (OR) Class G06F 9/30189 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230069366 | MISTRY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | KALSI ENGINEERING, INC. (Sugar Land, Texas) |
| ASSIGNEE(S) | KALSI ENGINEERING, INC. (Sugar Land, Texas) |
| INVENTOR(S) | Mital Chandrakant MISTRY (Richmond, Texas); Zachary W. LEUTWYLER (Richmond, Texas); Aaron P. RICHIE (Missouri City, Texas); Manmohan S. KALSI (Houston, Texas) |
| ABSTRACT | A passive thermal control valve comprising a thermal actuator coupled to a valve body having first and second ports. The thermal actuator including an actuator body having an inner bore. An adjustment stop engages the actuator body. A cylinder is received within the actuator body inner bore and the cylinder has a cylinder bore open at one end. An actuator spring within the actuator body biases the cylinder towards the adjustment stop. An actuator rod is at least partially received within the cylinder and has first and second ends. At least a portion of the actuator rod is allowed to extend through the open cylinder bore. A sealing element forms a seal between the actuator rod and the cylinder and defines a sealed chamber within the cylinder. A thermal fluid is contained within the cylinder. A lever mechanism is connected to the valve body and includes a lever having a first end connected to the valve body. A valve spool is connected to a lever second end. The valve spool is arranged and designed to close the first port and allow a system fluid to flow through the second port, close the second port and allow the system fluid to flow through the first port, or allow the system fluid to flow through both the first and second ports. |
| FILED | Monday, August 29, 2022 |
| APPL NO | 17/898204 |
| CURRENT CPC | Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 31/002 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 7/0126 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230069784 | Brown et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY (FORT DETRICK, Maryland) |
| ASSIGNEE(S) | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY (FORT DETRICK, Maryland) |
| INVENTOR(S) | Mark Brown (Myersville, Maryland); Scott Walters (Gaithersburg, Maryland); Mark Easterday (Jefferson, Maryland); Jay Bartlett (Adamstown, Maryland); Jaime Lee (Winchester, Virginia) |
| ABSTRACT | An apparatus for mounting and securing medical/surgical devices may be attached to a litter 40. The medical/surgical devices may include, for example, IV holders 186, aspirators 144, cardiac monitors 148, defibrillators 150, infusion pumps 152, ventilators 146 and other devices. The apparatus frame assembly 10 includes rails 12, 14, 16, 18, 20, 46, 48, 50, 52 having cross-sections of standard surgical rails, for attachment of slidable rail clamps 84, 104. Medical device mounts 108, 110, 112 are attached to the slidable rail clamps. The medical device mounts have height and/or rotational adjustment to improve patient access and view. The apparatus may be mounted longitudinally anywhere along the litter to maximize access to the patient. |
| FILED | Wednesday, March 03, 2021 |
| APPL NO | 17/797642 |
| CURRENT CPC | Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices A61G 13/101 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20230060163 | Ahmed et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GTI ENERGY (DES PLAINES, Illinois) |
| ASSIGNEE(S) | GTI ENERGY (DES PLAINES, Illinois) |
| INVENTOR(S) | Abdelallah Ahmed (Thousand Oaks, California); Jeffrey. A. Mays (Woodland Hills, California); John C. Vega, III (Camarillo, California); Shinjro Miyata (Malibu, California); David F. Morrison, II (Hesperia, California) |
| ABSTRACT | A system and method for communicating operation failure of a remote pipeline pneumatic device. A flow detector is used in combination with the pipeline pneumatic device. A controller in combination with the flow detector and a long range communication transmitter communicates an alarm upon detecting a predetermined flow, such as outside an expected amount. The controller can initiate a flow timer upon the actuation of the pneumatic device, and transmit an alarm upon the flow timer exceeding a predetermined value representing the expected amount. |
| FILED | Wednesday, August 31, 2022 |
| APPL NO | 17/899775 |
| CURRENT CPC | Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230060384 | Hafner |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Jacob Hafner (Overland Park, Kansas) |
| ABSTRACT | A system for manufacturing a part, the system comprising a power source, a rectifier, an electrical conduit, and a framework. The power source is configured to generate a high frequency, high current electrical signal. The rectifier is configured to convert the electrical signal to a direct current electrical signal. The electrical conduit is configured to carry the electrical signal. The framework is formed of electrically resistive metal having a relatively high melting point and is connected to the electrical conduit and at least partially encased in a powdered metal having a melting point lower than the melting point of the framework so that transmission of the electrical signal through the framework transitions at least some of the powdered metal into its molten state so that at least some of the molten metal cooled into its solidified state forms at least a portion of the part. |
| FILED | Wednesday, September 01, 2021 |
| APPL NO | 17/463700 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/20 (20210101) Original (OR) Class Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 11/0013 (20130101) B23K 11/241 (20130101) B23K 2101/24 (20180801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 7/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230060587 | Brewer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tony M. Brewer (Plano, Texas); David Boles (Austin, Texas); David Andrew Roberts (Wellesley, Massachusetts) |
| ABSTRACT | Disclosed in some examples are methods, systems, memory devices, and machine-readable mediums that allows an application thread to indicate an undo logging operation when calculations are beginning that may need to be rolled back if a crash or other failure occurs. During the undo logging operation, memory writes an identified memory are done to a copy and the original value is preserved. If the undo logging operation is committed, then the copy becomes the correct value and may then be subsequently used in place of the original, or the value stored in the copy is copied to the original. If the undo logging operation is abandoned, the copy is not preserved and the value goes back to the original. |
| FILED | Thursday, June 09, 2022 |
| APPL NO | 17/836529 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/064 (20130101) Original (OR) Class G06F 3/0619 (20130101) G06F 3/0631 (20130101) G06F 3/0659 (20130101) G06F 3/0673 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230061063 | REN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Amherst, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shenqiang REN (Williamsville, New York); Lu AN (Buffalo, New York) |
| ABSTRACT | Ceramic foam fiber composites, methods of making ceramic foam fiber composites, and uses of ceramic foam fiber composites. The ceramic foam fiber composites may be made by contacting one or more fiber(s); one or more ceramic precursor(s); one or more pore-forming gas-forming additive(s) (one or more inert gas-generating agent(s)); one or more catalyst(s); and, optionally, one or more additive(s), where the contacting is results in formation of an inert gas and the ceramic foam-fiber composite is formed. A ceramic foam-fiber composite may include a plurality of fibers, where at least a portion or all of the fibers individually comprise a ceramic foam disposed on at least a portion or all of a surface of the fiber. A ceramic foam-fiber composite may exhibit one or more or all of the following: thermal stability, mechanical strength, soundproof/acoustic insulation characteristics. A ceramic foam-fiber composite material may be used as a building material. |
| FILED | Monday, January 11, 2021 |
| APPL NO | 17/758621 |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/10 (20130101) C04B 35/14 (20130101) C04B 35/80 (20130101) Original (OR) Class C04B 38/02 (20130101) C04B 38/007 (20130101) C04B 38/0054 (20130101) C04B 2235/3217 (20130101) C04B 2235/3418 (20130101) C04B 2235/5216 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230061431 | Sussman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Michael R. Sussman (Cross Plains, Wisconsin); J. Leon Shohet (Madison, Wisconsin); Faraz A. Choudhury (Madison, Wisconsin); Joshua M. Blatz (Monona, Wisconsin); Benjamin B. Minkoff (Madison, Wisconsin); Daniel I. Benjamin (Madison, Wisconsin) |
| ABSTRACT | This disclosure provides methods, systems, and compositions of matter for studying solvent accessibility and three-dimensional structure of biological molecules. A plasma can be used to generate marker radicals, which can interact with a biological molecule and mark the solvent-accessible portions of the biological molecule. |
| FILED | Friday, April 08, 2022 |
| APPL NO | 17/716499 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/088 (20130101) B01J 2219/0809 (20130101) B01J 2219/0894 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/28 (20130101) G01N 33/50 (20130101) Original (OR) Class G01N 33/487 (20130101) G01N 33/6848 (20130101) G01N 2333/765 (20130101) G01N 2333/90216 (20130101) G01N 2333/91215 (20130101) G01N 2440/00 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0031 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230061782 | AGGOUNE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DELPHI TECHNOLOGIES IP LIMITED (St. Michael, Barbados) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Karim AGGOUNE (Auburn Hills, Michigan); Gerard W. MALACZYNSKI (Bloomfield Hills, Michigan); Claude P. POULL (Houdemont, Belgium) |
| ABSTRACT | A method for estimating energy consumption of a vehicle includes receiving, from a remotely located computing device, standardized energy consumption data corresponding to at least one other vehicle, the standardized energy consumption data corresponding to energy consumption of the at least one other vehicle as a function of speed. The method further includes generating a scaling factor by comparing the energy consumption data corresponding to the energy consumption of the vehicle as a function of speed with the standardized energy consumption data. The method further includes scaling the standardized energy consumption data to generate a profile of the energy consumption efficiency of the vehicle. The method further includes generating a signal to selectively adjust at least one of a speed of the vehicle, at least one route characteristic of a portion of a route being traversed by the vehicle, and a torque demand of the vehicle. |
| FILED | Wednesday, September 01, 2021 |
| APPL NO | 17/464596 |
| CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 30/143 (20130101) B60W 40/076 (20130101) B60W 2510/083 (20130101) B60W 2552/15 (20200201) B60W 2556/45 (20200201) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/3469 (20130101) Original (OR) Class Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere G07C 5/008 (20130101) G07C 5/0808 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230061924 | PRINCE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kevin Joseph PRINCE (Golden, Colorado); Lance Michael WHEELER (Golden, Colorado) |
| ABSTRACT | The present disclosure relates to a photovoltaic (PV) device that includes a color-conversion layer that includes at least one of a color-tuning layer and/or an intermediate layer and a photovoltaic layer where the color-conversion layer changes the appearance of the PV device when compared to a similar PV device constructed without the color-conversion layer, the color-conversion layer increases a power output of the PV device by at least one of reflecting light to the PV layer or emitting light which is redirected to the PV layer, and the device is at least partially transparent to light in the visible spectrum. |
| FILED | Wednesday, August 24, 2022 |
| APPL NO | 17/894992 |
| CURRENT CPC | Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 11/24 (20130101) C09B 67/0063 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/02 (20130101) C09K 11/06 (20130101) C09K 2211/1007 (20130101) C09K 2211/1018 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/209 (20130101) Original (OR) Class H01G 9/2009 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/447 (20130101) H01L 51/4253 (20130101) H01L 51/4293 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 20/26 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230062711 | METAFERIA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Wondwosen Tilahun METAFERIA (Rio Rancho, New Mexico); Kevin Louis SCHULTE (Denver, Colorado); Aaron Joseph PTAK (Littleton, Colorado); John David SIMON (Austin, Texas) |
| ABSTRACT | Disclosed herein is the controlled epitaxy of AlxGa1-xAs, AlxIn1-xP, and AlxGayIn1-x-yP by hydride vapor phase epitaxy (HVPE) through use of an external AlCl3 generator. |
| FILED | Thursday, October 01, 2020 |
| APPL NO | 17/754503 |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/14 (20130101) Original (OR) Class C30B 29/40 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0262 (20130101) H01L 21/02395 (20130101) H01L 21/02433 (20130101) H01L 21/02543 (20130101) H01L 21/02546 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230063553 | Young et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Barbara Diane Young (Raymore, Missouri); Steven James Sedlock (Raymore, Missouri) |
| ABSTRACT | Systems, methods, components, and parts are provided for improving casting and electroplating performance of a plated cast part by doping a semiconductor material with an electrically active dopant before mixing the semiconductor material into a base material. The doped semiconductor material improves the castability of the base material and has an improved electrical conductivity which is closer to that of the base material such that a consistency of a subsequent plating on the part is improved. |
| FILED | Tuesday, August 31, 2021 |
| APPL NO | 17/462273 |
| CURRENT CPC | Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 3/38 (20130101) C25D 3/44 (20130101) Original (OR) Class C25D 7/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230064358 | POULL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | DELPHI TECHNOLOGIES IP LIMITED (St. Michael, Barbados) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Claude P. POULL (Houdemont, Belgium); Karim AGGOUNE (Auburn Hills, Michigan) |
| ABSTRACT | A method for providing a visual driving speed recommendation to an operator of a vehicle includes determining a current speed; determining a corresponding energy efficient speed; determining a higher corresponding less energy efficient speed; determining a first transition range between the corresponding energy efficient speed and the higher corresponding less energy efficient speed; and displaying, on a display, a display zone, the display zone comprising: a first indicator corresponding to the current speed; a first pattern corresponding to the corresponding energy efficient speed; a second pattern different from the first pattern and corresponding to the higher corresponding less energy efficient speed; and a first pattern range therebetween corresponding to the first transition range. |
| FILED | Wednesday, September 01, 2021 |
| APPL NO | 17/464236 |
| CURRENT CPC | Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles B60K 35/00 (20130101) B60K 2370/167 (20190501) B60K 2370/188 (20190501) Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 30/143 (20130101) B60W 30/18072 (20130101) B60W 40/105 (20130101) B60W 50/14 (20130101) Original (OR) Class B60W 2050/146 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230064696 | Song et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ESS TECH, INC. (Wilsonville, Oregon) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yang Song (West Linn, Oregon); Craig E. Evans (West Linn, Oregon) |
| ABSTRACT | A method of cleansing a redox flow battery system may include operating the redox flow battery system in a charge, discharge, or idle mode, and responsive to a redox flow battery capacity being less than a threshold battery capacity, mixing the positive electrolyte with the negative electrolyte. In this way, battery capacity degradation following cyclic charging and discharging of the redox flow battery system can be substantially reduced. |
| FILED | Wednesday, October 26, 2022 |
| APPL NO | 18/049987 |
| CURRENT CPC | Image or Video Recognition or Understanding G06V 40/1306 (20220101) G06V 40/1394 (20220101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/188 (20130101) Original (OR) Class H01M 8/0693 (20130101) H01M 8/04186 (20130101) H01M 8/04611 (20130101) H01M 8/04932 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230065356 | Giacomini |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brookhaven Science Associates, LLC (Upton, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gabriele Giacomini (Ridge, New York) |
| ABSTRACT | A method for fabricating a low-gain avalanche diode (LGAD) device is provided. The method includes: forming a low-resistivity n-type semiconductor substrate in a first silicon wafer; forming a p-type gain layer in an upper surface of a high-resistivity p-type second silicon wafer; bonding the first and second wafers such that the upper surface of the second wafer proximate the gain layer contacts the semiconductor substrate in the first wafer to form a bonded wafer structure, whereby a back surface of the second wafer becomes an upper surface of the bonded wafer structure; forming a plurality of p-type electrodes in the upper surface of the bonded wafer structure; and forming a conductive layer on at least a portion of the respective p-type electrodes and on a back surface of the semiconductor substrate, the conductive layer providing electrical connection to the LGAD device. |
| FILED | Tuesday, August 31, 2021 |
| APPL NO | 17/462363 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14643 (20130101) H01L 29/868 (20130101) H01L 29/66113 (20130101) Original (OR) Class H01L 31/107 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230065796 | ZINN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | KUPRION INC. (San Jose, California) |
| ASSIGNEE(S) | KUPRION INC. (San Jose, California) |
| INVENTOR(S) | Alfred A. ZINN (Palo Alto, California); Khanh NGUYEN (San Jose, California) |
| ABSTRACT | Printed circuit boards may be formed using ceramic substrates with high thermal conductivity to facilitate heat dissipation. Metal nanoparticles, such as copper nanoparticles, may be used to form conductive traces and fill through-plane vias upon the ceramic substrates. Multi-layer printed circuit boards may comprise two or more ceramic substrates adhered together, wherein each ceramic substrate has one or more conductive traces defined thereon and the one or more conductive traces are formed through consolidation of metal nanoparticles. The one or more conductive traces in a first ceramic substrate layer are in electrical communication with at least one second ceramic substrate layer adjacent thereto. |
| FILED | Friday, February 26, 2021 |
| APPL NO | 17/760079 |
| CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/092 (20130101) H05K 1/115 (20130101) H05K 1/181 (20130101) H05K 1/183 (20130101) H05K 1/0306 (20130101) Original (OR) Class H05K 3/46 (20130101) H05K 3/107 (20130101) H05K 3/303 (20130101) H05K 3/4038 (20130101) H05K 2201/09227 (20130101) H05K 2201/09563 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230067004 | MOBLEY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Research Triangle Institute (Research Triangle Park, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul MOBLEY (Raleigh, North Carolina); Shaojun James ZHOU (Cary, North Carolina); Samuel John THOMPSON (Chapel Hill, North Carolina); Jak TANTHANA (Durham, North Carolina); Aravind Villava Rayer RABINDRAN (Morrisville, North Carolina); Marty LAIL (Raleigh, North Carolina) |
| ABSTRACT | A method for reducing the concentration of amines in a wash liquid stream exiting a wash section in an acid gas scrubbing process includes introducing the wash liquid stream exiting the wash section of the acid gas scrubbing process to an adsorbent material, wherein the wash liquid stream has a first concentration of amines. The wash liquid stream having the first concentration of amines is flowed through the adsorbent material, and the adsorbent material retains at least a portion of the amines thereby providing a wash liquid stream having a second, reduced concentration of amines. The wash stream with reduced concentration of amines is recycled back to the wash section to remove amines more effectively from the acid gas being scrubbed. The adsorbent material can be regenerated for reuse. Amine recovered from the regenerated adsorbent material can be recycled to the process for reuse. |
| FILED | Tuesday, January 26, 2021 |
| APPL NO | 17/759654 |
| CURRENT CPC | Separation B01D 53/1425 (20130101) B01D 53/1475 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/20 (20130101) B01J 20/3416 (20130101) B01J 20/3466 (20130101) B01J 20/3475 (20130101) B01J 20/28016 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/283 (20130101) Original (OR) Class C02F 2103/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230067623 | Stahl et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shannon Stahl (Madison, Wisconsin); Jason Bates (Madison, Wisconsin) |
| ABSTRACT | A method of making an M-N—C catalyst is disclosed. The method includes the steps of (a) contacting an N-doped carbon support with a basic solution that includes a metal salt, whereby the N-doped carbon support is metalated by the metal cation of the metal salt to form one or more chelated metal-nitrogen complexes (MNx species); and (b) subsequently contacting the metalated N-doped carbon support with an acid, whereby the one or more MNx species formed on the N-doped carbon support in step (a) remain intact while other species are removed. The resulting composition may be catalytically activated by heat treating the composition. The activated catalyst may be used to catalyze a wide range of chemical reactions. |
| FILED | Wednesday, August 10, 2022 |
| APPL NO | 17/885205 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/18 (20130101) B01J 31/1691 (20130101) Original (OR) Class B01J 37/08 (20130101) B01J 37/0203 (20130101) B01J 37/0205 (20130101) B01J 37/0209 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 11/075 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230067875 | BOND et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tiziana C. BOND (Livermore, California); Sara Elizabeth HARRISON (Fremont, California); Catherine E. REINHARDT (Livermore, California); Payal Kamlesh SINGH (San Diego, California); Victor V. KHITROV (San Ramon, California) |
| ABSTRACT | The present disclosure relates to a method of forming a tapered optical fiber, where the optical fiber has a cladding encasing a core and has an initial outer diameter. The method involves applying opposing forces to spaced apart sections of the optical fiber. The spaced apart sections define a length portion representing a waist region. While applying the opposing forces, simultaneously applying heat to the waist region to gradually produce a taper of the optical fiber within the waist region. The taper has a first diameter at a midpoint of the waist region which is less than the initial outer diameter. An etch operation is then performed by chemically etching at least a subportion of the waist region of the optical fiber to reduce the subportion to a second diameter which is less than the first diameter. |
| FILED | Tuesday, August 31, 2021 |
| APPL NO | 17/462734 |
| CURRENT CPC | Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 25/68 (20130101) Optical Elements, Systems, or Apparatus G02B 6/2552 (20130101) Original (OR) Class G02B 6/3692 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230068006 | Alexander |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | DayLyte, Inc. (Knoxville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Caleb Tyler Alexander (Knoxville, Tennessee) |
| ABSTRACT | Methods of improving an aqueous metal-air battery are disclosed. The methods include forming a solid electrolyte on a conductive substrate; forming a protective surface on the solid electrolyte; having and improving separate oxygen reduction and oxygen evolution electrodes; improving the gas diffusion of the oxygen reduction and evolution electrodes; and improving the structure of the battery cell. Improved metal-air batteries including such improvements are further disclosed. |
| FILED | Thursday, September 01, 2022 |
| APPL NO | 17/901358 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 12/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230068289 | Pino |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Ruben Arturo Pino (Kansas City, Missouri) |
| ABSTRACT | An enclosure for a three-dimensional printing system comprises a plurality of walls and a glass panel. The walls define an inner chamber for receiving the three-dimensional printing system and an opening that provides access to the inner chamber from outside the walls. The glass panel is shiftable between a closed position in which the panel blocks access to the inner chamber and an open position in which the panel allows access to the inner chamber via the opening. |
| FILED | Friday, July 08, 2022 |
| APPL NO | 17/860205 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/25 (20170801) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230068356 | AGGOUNE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | DELPHI TECHNOLOGIES IP LIMITED (St. Michael, Barbados) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Karim AGGOUNE (Auburn Hills, Michigan); Gerard W. MALACZYNSKI (Bloomfield Hills, Michigan); Claude P. POULL (Houdemont, Belgium) |
| ABSTRACT | A method for providing a cruising speed recommendation to an operator of a vehicle includes determining a projected route; receiving route characteristic data including route elevation data; determining a sampling resolution; sampling the route elevation data at the sampling resolution to generate sampled route elevation data; determining at least one start of uphill position and at least one start of downhill position; determining at least one cruise speed route segment based at least in part on the at least one start of uphill position and the at least one start of downhill position; determining a corresponding cruising speed for the at least one cruise speed route segment based at least in part on one or more of the route elevation data and the sampled route elevation data; and communicating the corresponding cruising speed for the at least one cruise speed route segment. |
| FILED | Wednesday, September 01, 2021 |
| APPL NO | 17/464084 |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/3469 (20130101) G01C 21/3492 (20130101) G01C 21/3697 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230068726 | Doudna et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jennifer A. Doudna (Berkeley, California); Jillian F. Banfield (Berkeley, California); Brady F. Cress (Berkeley, California); Benjamin E. Rubin (Berkeley, California); Spencer Diamond (Berkeley, California); Adam M. Deutschbauer (Berkeley, California) |
| ABSTRACT | The present disclosure provides a transposon system comprising: i) a nucleotide sequence encoding polypeptides that form a CRISPR-associated transposase complex; ii) a nucleotide sequence encoding a guide RNA; and iii) a transposon, or an insertion site for a transposon, flanked by CAST complex recognition sites. The present disclosure provides a prokaryotic cell comprising a subject transposon system. The transposon system is useful for editing the genome of a target prokaryotic cell. The present disclosure provides methods for editing the genome of a target prokaryotic cell. The present disclosure further provides systems and methods for identifying, within a heterogeneous population of prokaryotic cells, prokaryotic species that are susceptible to genetic modification and gene editing. |
| FILED | Thursday, January 28, 2021 |
| APPL NO | 17/794166 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 9/22 (20130101) Original (OR) Class C12N 15/11 (20130101) C12N 15/74 (20130101) C12N 15/111 (20130101) C12N 15/1065 (20130101) C12N 2310/20 (20170501) C12N 2800/80 (20130101) C12N 2800/101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230068910 | Rotsch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Rotsch (Montgomery, Illinois); Jerry A. Nolen, JR. (Chicago, Illinois); Sergey D. Chemerisov (Lisle, Illinois); James L. Bailey (Hinsdale, Illinois); Ronald T. Kmak (Homer Glen, Illinois) |
| ABSTRACT | A remotely controllable sublimation apparatus that includes a crucible block adapted to retain a crucible containing a solid mixture comprising one or more radionuclides, a first heating block comprising one or more first heating elements configured to selectively generate heat having a first temperature sufficient to at least partially sublime the solid mixture, and a collection vessel coupled to the first heating block. The crucible block is movable, relative to the first heating block, between an open position and a closed positon. When the crucible block is in the closed position, the one or more first heating elements are configured to heat the crucible block to the first temperature, thereby heating the solid mixture and producing a vapor that is collected by the collection vessel and leaving a solid residue in the crucible that substantially consists only of the one or more radionuclides. |
| FILED | Friday, August 27, 2021 |
| APPL NO | 17/460150 |
| CURRENT CPC | Separation B01D 7/00 (20130101) Original (OR) Class Furnaces, Kilns, Ovens, or Retorts in General; Open Sintering or Like Apparatus F27B 14/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230069376 | MARTIN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Trevor Russell MARTIN (Boulder, Colorado); Kyusung PARK (Seongnam, South Korea) |
| ABSTRACT | The present disclosure relates to a composition having a structure defined by , where |
| FILED | Wednesday, August 31, 2022 |
| APPL NO | 17/900762 |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 293/00 (20130101) C08F 297/044 (20130101) Compositions of Macromolecular Compounds C08L 53/025 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230069457 | Tripathy |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Prabhat K. Tripathy (Idaho Falls, Idaho) |
| ABSTRACT | An electrode comprising a substrate; a metal layer on the substrate; and a solid solution between the metal layer and the substrate. A method of forming an electrode comprising forming a molten salt bath, plating, from the molten salt bath, a metal onto a substrate, and annealing the metal and the substrate to form an electrode comprising a solid solution between the metal and the substrate, wherein the electrode is substantially free of intermetallic phases. A method of forming an electrode comprising forming, on a substrate, a metal layer using digital light processing and annealing the substrate and the metal layer to form a solid solution between the substrate and the metal layer, wherein the electrode is substantially free of intermetallic phases. |
| FILED | Wednesday, September 01, 2021 |
| APPL NO | 17/446692 |
| CURRENT CPC | Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 5/50 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/02 (20130101) H01B 5/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230069516 | Forest et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Cary Brett Forest (Madison, Wisconsin); Jonathan Pizzo (Madison, Wisconsin); Oliver Schmitz (Madison, Wisconsin) |
| ABSTRACT | A divertor for system supporting high-energy plasma for fusion employs permanent magnets providing far weaker magnetic field strength than conventionally used in cryogenic magnetic systems through an ability to place the permanent magnets in close proximity to the plasma containment volume. |
| FILED | Monday, August 30, 2021 |
| APPL NO | 17/461366 |
| CURRENT CPC | Fusion Reactors G21B 1/05 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230069606 | Bond et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tiziana C. Bond (Livermore, California); Allan Shih-Ping Chang (San Ramon, California) |
| ABSTRACT | Direct detection of carbon dioxide leakage in a carbon storage well is obtained using an optical fiber adapted to be positioned in the carbon storage well, a detection unit operatively connected to the optical fiber, and a leak sensor section incorporated in the optical fiber. |
| FILED | Monday, August 30, 2021 |
| APPL NO | 17/461309 |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 3/047 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/004 (20130101) G01N 33/246 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230069732 | AGGOUNE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | DELPHI TECHNOLOGIES IP LIMITED (St. Michael, Barbados) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Karim AGGOUNE (Auburn Hills, Michigan); Gerard W. MALACZYNSKI (Bloomfield Hills, Michigan); Claude P. POULL (Belgium, Germany) |
| ABSTRACT | A method for providing a coast recommendation for an operator of a vehicle, including receiving vehicle position data; determining a projected route; determining a first speed change position and a first speed change target speed; determining a first residual speed and a first residual speed position based at least in part on the first speed change position and the first speed change target speed; determining a first lower speed envelope; determining an overall lower speed envelope based at least in part on the first residual speed; determining an upper speed envelope; determining a target speed profile based at least in part on the first residual speed, the first residual speed position, the first lower speed envelope, and the upper speed envelope; determining a coast start point based at least in part on the target speed profile; and communicating the coast start point to the operator of the vehicle. |
| FILED | Wednesday, September 01, 2021 |
| APPL NO | 17/463610 |
| CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 30/18072 (20130101) B60W 50/14 (20130101) Original (OR) Class B60W 2520/105 (20130101) B60W 2520/125 (20130101) B60W 2554/00 (20200201) B60W 2555/20 (20200201) B60W 2555/40 (20200201) B60W 2555/60 (20200201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20230060178 | Klausen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rebekka Klausen (Baltimore, Maryland); Yuyang Ji (Baltimroe, Maryland) |
| ABSTRACT | Described are methods using aromatic vinyl borane monomers for the preparation of highly functionalized copolymers bearing vinyl alcohol, lactone, and ester side chains. |
| FILED | Wednesday, December 02, 2020 |
| APPL NO | 17/781455 |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 130/06 (20130101) Original (OR) Class C08F 212/10 (20130101) C08F 212/32 (20130101) C08F 230/065 (20200201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230060417 | SHREVE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Matthew A. SHREVE (Webster, New York); Eric COCKER (Redwood City, California) |
| ABSTRACT | The present specification relates to image capture. More specifically, it relates to selective image capture for sensor carrying devices or floats deployed, for example, on the open sea. In one form, data is generated on the sensor carrying devices or floats by an on-board Inertial Measurement Unit (IMU) and is used to automatically predict the wave motion of the sea. These predictions are then used to determine an acceptable set of motion parameters that are used to trigger the on-board camera(s). The camera(s) then capture images. One consideration is that images captured at or near the peak of a wave crest with minimal pitch and roll will contain fewer obstructions (such as other waves). Such images provide a view further into the horizon to, for example, monitor maritime sea traffic and other phenomenon. Therefore, the likelihood of capturing interesting objects such as ships, boats, garbage, birds, . . . etc. is increased. These images may then be further processed and/or transmitted in a variety of manners. |
| FILED | Tuesday, August 31, 2021 |
| APPL NO | 17/463433 |
| CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 79/15 (20200101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 13/004 (20130101) Pictorial Communication, e.g Television H04N 7/188 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230061431 | Sussman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Michael R. Sussman (Cross Plains, Wisconsin); J. Leon Shohet (Madison, Wisconsin); Faraz A. Choudhury (Madison, Wisconsin); Joshua M. Blatz (Monona, Wisconsin); Benjamin B. Minkoff (Madison, Wisconsin); Daniel I. Benjamin (Madison, Wisconsin) |
| ABSTRACT | This disclosure provides methods, systems, and compositions of matter for studying solvent accessibility and three-dimensional structure of biological molecules. A plasma can be used to generate marker radicals, which can interact with a biological molecule and mark the solvent-accessible portions of the biological molecule. |
| FILED | Friday, April 08, 2022 |
| APPL NO | 17/716499 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/088 (20130101) B01J 2219/0809 (20130101) B01J 2219/0894 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/28 (20130101) G01N 33/50 (20130101) Original (OR) Class G01N 33/487 (20130101) G01N 33/6848 (20130101) G01N 2333/765 (20130101) G01N 2333/90216 (20130101) G01N 2333/91215 (20130101) G01N 2440/00 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0031 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230062256 | FAN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Xudong FAN (Ann Arbor, Michigan); Xueding WANG (Ann Arbor, Michigan); Xuzhou LI (Ann Arbor, Michigan); Wei ZHANG (Ann Arbor, Michigan); William Yanli WANG (Ann Arbor, Michigan); Xiaoqin WU (Ann Arbor, Michigan); Xiaotian TAN (Ann Arbor, Michigan); Brendon BAKER (Ann Arbor, Michigan); Yannis M. PAULUS (Ann Arbor, Michigan) |
| ABSTRACT | An imaging system for cell-based therapies is provided. The imagining system includes one or more optical tags configured for insertion into a cell or biological tissue, an excitation light source configured to illuminate the one or more optical tags; a detector configured to measure optical emission of the one or more optical tags; an imaging subsystem configured to determine a three-dimensional location of each of the one or more optical tags in the cell or biological tissue; and a controller in electrical communication with the excitation light source, the detector, and the imaging subsystem. Each of the one or more optical tags has a contrasting feature and includes a fluorescent material. The contrasting feature may be defined by at least one of a refractive index, shape, color, and laser emission of each optical tag of the one or more optical tags. |
| FILED | Thursday, January 28, 2021 |
| APPL NO | 17/795581 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/102 (20130101) A61B 3/1233 (20130101) A61B 3/1241 (20130101) Original (OR) Class A61B 8/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/4795 (20130101) G01N 21/6428 (20130101) G01N 33/582 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230062497 | BRGOCH et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | University of Houston System (Houston, Texas) |
| INVENTOR(S) | Jakoah BRGOCH (Houston, Texas); Shruti HARIYANI (Houston, Texas) |
| ABSTRACT | Provided herein are phosphors of the general molecular formula: A3-2xEuxMP3O9N, wherein the variables are as defined herein. Methods of producing the phosphors are also provided. In some aspects, the present disclosure provides light-emitting devices comprising these phosphors. |
| FILED | Wednesday, August 24, 2022 |
| APPL NO | 17/821907 |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/7728 (20130101) C09K 11/7731 (20130101) Original (OR) Class C09K 11/7787 (20130101) C09K 11/7789 (20130101) C09K 11/77346 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230062528 | Rao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sunil Rao (Tempe, Arizona); Vivek Sivaraman Narayanaswamy (Tempe, Arizona); Michael Esposito (Phoenix, Arizona); Andreas Spanias (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona) |
| INVENTOR(S) | Sunil Rao (Tempe, Arizona); Vivek Sivaraman Narayanaswamy (Tempe, Arizona); Michael Esposito (Phoenix, Arizona); Andreas Spanias (Tempe, Arizona) |
| ABSTRACT | Various embodiments of a system and associated method for detection of COVID-19 and other respiratory diseases through classification of audio samples are disclosed herein. The system utilizes features directly extracted from the coughing audio and develops automated diagnostic tools for COVID-19. In particular, the present application discusses a novel modification of a deep neural network architecture by using log-mel spectrograms of the audio excerpts and by optimizing a combination of binary cross-entropy and focal loss parameters. One embodiment of the system achieved an average validation AUC of 82.23% and a test AUC of 78.3% at a sensitivity of 80.49%. |
| FILED | Friday, August 12, 2022 |
| APPL NO | 17/819519 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0823 (20130101) Original (OR) Class A61B 5/7267 (20130101) A61B 5/7275 (20130101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 25/18 (20130101) G10L 25/30 (20130101) G10L 25/66 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) G16H 50/70 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230062951 | Ramani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Karthik Ramani (West Lafayette, Indiana); Ana Villanueva Pérez (West Lafayette, Indiana) |
| ABSTRACT | An augmented reality system for developing and providing augmented reality learning experiences is disclosed. The augmented reality system advantageously combines augmented reality with the capabilities of cloud technology to provide a pull-based collaborative model, in which students and instructors collaborate by uploading, sharing, and downloading augmented reality learning content. The augmented reality system enables students to improve the augmented reality learning content by adding contributions to the original augmented reality learning content that was created by an instructor. |
| FILED | Monday, October 24, 2022 |
| APPL NO | 18/049065 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 11/00 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 7/00 (20130101) G09B 19/003 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 67/131 (20220501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230064628 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, a body Corporate (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kai Yu (Denver, Colorado); Xu He (Littleton, Colorado); Martin Dunn (Denver, Colorado); Arif Abdullah (Denver, Colorado) |
| ABSTRACT | A printer head for three-dimensional printing of a continuous fiber-reinforced thermoset composite may include a deposition syringe, a fiber housing, and a feeding tube. The deposition syringe may define a resin reservoir, an air chamber, and a first inlet port configured to deliver a first flow of air to the air chamber. The deposition syringe may include a syringe body and a piston. The syringe body may include an inlet section, a needle section, and a converging section disposed between the inlet section and the needle section. The fiber housing may define a fiber chamber and a second inlet port configured to deliver a second flow of air to the fiber chamber. The feeding tube may extend from the fiber chamber to the needle section and may be configured to receive the second flow of air therein and to guide a fiber from the fiber chamber to the needle section. |
| FILED | Wednesday, August 31, 2022 |
| APPL NO | 17/900856 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/165 (20170801) B29C 64/209 (20170801) Original (OR) Class B29C 64/227 (20170801) B29C 64/264 (20170801) B29C 64/336 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230064807 | Koskella et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Britt Koskella (Berkeley, California); Elijah Curtis P. Mehlferber (Berkeley, California) |
| ABSTRACT | A synthetic microbial community (SynCom) agricultural crop fertilizer composition comprises a microbial stabilizing buffer and bacterial strains configured to mimic the natural diversity of the bacterial community found in the crop phyllosphere microbiome, but at a reduced complexity, yet sufficient to effectively provide increased plant productivity and/or disease protection. |
| FILED | Friday, November 04, 2022 |
| APPL NO | 17/981384 |
| CURRENT CPC | Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 7/06 (20130101) Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/20 (20200101) Original (OR) Class Biocidal, Pest Repellant, Pest Attractant or Plant Growth Regulatory Activity of Chemical Compounds or Preparations A01P 3/00 (20210801) A01P 21/00 (20210801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230065149 | Hersam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark C. Hersam (Wilmette, Illinois); Woo Jin Hyun (Shantou, China PRC); Lindsay E. Chaney (Evanston, Illinois) |
| ABSTRACT | One aspect of the invention relates to an ionogel electrolyte ink including an ionic liquid; and a gelling matrix material. The gelling matrix material is mixed with the ionic liquid in at least one solvent. |
| FILED | Tuesday, October 18, 2022 |
| APPL NO | 17/968180 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/623 (20130101) H01M 4/625 (20130101) H01M 10/0525 (20130101) H01M 10/0565 (20130101) Original (OR) Class H01M 10/0585 (20130101) H01M 2004/027 (20130101) H01M 2300/0082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230066952 | Huang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina); ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | He Huang (Cary, North Carolina); Yue Wen (Raleigh, North Carolina); Jennie Si (Phoenix, Arizona); Xiang Gao (Tempe, Arizona); Minhan Li (Raleigh, North Carolina) |
| ABSTRACT | Systems and methods for tuning a powered prosthesis are described herein. A system includes a powered prosthesis including a joint, a motor mechanically coupled to the joint, a plurality of sensors, a finite state machine, and an impedance controller. The sensors are configured to measure a plurality of gait parameters, and the finite state machine is configured to determine a gait cycle state. The impedance controller is configured to output a control signal for adjusting a torque of the motor, where the torque is adjusted as a function of the measured gait parameters and a plurality of impedance control parameters, and where the impedance control parameters are dependent on the gait cycle state. The system also includes a reinforcement learning controller operably connected to the powered prosthesis. The reinforcement learning controller is configured to tune the impedance control parameters to achieve a target gait characteristic using a training data set. |
| FILED | Monday, November 16, 2020 |
| APPL NO | 17/792695 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/68 (20130101) Original (OR) Class A61F 2002/7625 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230067000 | Gouma et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pelagia I. Gouma (Columbus, Ohio); Owen Oledele Abe (Columbus, Ohio) |
| ABSTRACT | An electrochromic device comprising a substrate, a set of electrodes disposed on or within the substrate, and a layer comprising ε-WO3 disposed in electrical communication with the set of electrodes, wherein the layer of ε-WO3 exhibits polarization switching are described. Methods of making and using the electrochromic devices are also described. The electrochromic devices are used for detecting acetone in a fluid. The observed change in color of the ε-WO3 layer can be correlated with a subject's medical condition, such as diabetes. |
| FILED | Monday, October 10, 2022 |
| APPL NO | 18/045198 |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 41/02 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/82 (20130101) C01P 2002/90 (20130101) C01P 2004/64 (20130101) C01P 2006/60 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/78 (20130101) G01N 33/497 (20130101) G01N 2033/4975 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/155 (20130101) G02F 1/1524 (20190101) Original (OR) Class G02F 2202/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230067015 | EBRAHIMI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Seyedehaida EBRAHIMI (University Park, Pennsylvania); Chen ZHOU (University Park, Pennsylvania); Jasna KOVAC (University Park, Pennsylvania); Zhiwen LIU (University Park, Pennsylvania); Keren ZHOU (University Park, Pennsylvania) |
| ABSTRACT | A method for antibacterial susceptibility testing includes preparing a set of two or more samples of a plurality of bacterial cells from a patient; adding a different amount of a selected drug to each sample; illuminating at least a portion of a sample using a coherent illumination source; capturing a series of speckle images over time of at least a portion of the illuminated sample; and determining an inhibition status of the sample using a machine-learning classifier applied to the series of speckle images. The steps of illuminating the sample, capturing a series of images, and determining an inhibition status are repeated for each sample of the set of two or more samples. The method may include transforming the series of speckle images to a frequency series of speckle images; and determining the inhibition status of the sample uses the machine-learning classifier applied to the frequency series of speckle images. |
| FILED | Wednesday, February 03, 2021 |
| APPL NO | 17/759995 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/4788 (20130101) G01N 2021/479 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230067318 | Thomas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Jayan Thomas (Orlando, Florida); Deepak Pandey (Orlando, Florida); Kowsik Sambath Kumar (Orlando, Florida) |
| ABSTRACT | A dual-function supercapacitor carbon fiber composite stores electrical energy and functions, for example, as the body shell of electric vehicles (EVs). This is achieved with a vertically aligned graphene on carbon fiber electrode, upon which metal oxides were deposited to obtain ultra-high energy density anode and cathode. A high-strength multilayer carbon composite assembly is fabricated using an alternate layer patterning configuration of epoxy and polyacrylamide gel electrolyte. The energized composite delivers a high areal energy density of 0.31 mWh cm−2 at 0.3 mm thickness and showed a high tensile strength of 518 MPa, bending strength of 477 MPa, and impact strength 2666 J/m. To show application in EVs, a toy car body fabricated with energized composite operates using the energy stored inside the frame. Moreover, when integrated with a solar cell, this composite powered an IoT (interne of things) device, showing feasibility in communication satellites. |
| FILED | Thursday, June 16, 2022 |
| APPL NO | 17/842145 |
| CURRENT CPC | Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 50/40 (20190201) Indexing Scheme Relating to Aspects Cross-cutting Vehicle Technology B60Y 2200/91 (20130101) Motor Vehicles; Trailers B62D 29/043 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/24 (20130101) H01G 11/28 (20130101) H01G 11/40 (20130101) Original (OR) Class H01G 11/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230067663 | Alabastri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Alessandro Alabastri (Houston, Texas); Pratiksha Dongare (Houston, Texas); Nancy J. Halas (Houston, Texas); Peter J. Nordlander (Houston, Texas); Oara Neumann (Houston, Texas) |
| ABSTRACT | A method includes providing a resonant thermal oscillator in a thermofluidic system having at least two counter-flowing liquid streams separated by at least a spectrum absorbing material, wherein the spectrum absorbing material is hydrophobic, light-absorbing, and photothermal, and adjusting a flow rate in at least one of the counter-flowing liquid streams to maximize heat transfer between the at least two counter-flowing liquid streams. |
| FILED | Friday, February 12, 2021 |
| APPL NO | 17/760070 |
| CURRENT CPC | Separation B01D 1/0035 (20130101) B01D 1/0041 (20130101) Original (OR) Class B01D 1/0082 (20130101) B01D 3/007 (20130101) B01D 61/364 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/008 (20130101) C02F 1/14 (20130101) C02F 1/043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230067892 | MOSKOWITZ et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | IntuiTap Medical, Inc. (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicole C. MOSKOWITZ (Monsey, New York); Jessica TRAVER (Sierra Madre, California); Xavier GARCIA-ROJAS (The Woodlands, Texas); Yashar GANJEH (Chicago, Illinois); Matthew CRUZ (Chicago, Illinois); Jonathan Rae PLUMB (Halstead, United Kingdom); Jack Alexander LOWE (Leeds, United Kingdom); Alexander Keith Gomer Pratten JONES (Cambridge, United Kingdom); Geoffrey HUTCHINS (Park Ridge, Illinois); Ann GRAFF (Chicago, Illinois); Mahesh VAIDYANATHAN (Houston, Texas) |
| ABSTRACT | Provided are systems and methods for tactile sensing of a target tissue region of a patient in need thereof. |
| FILED | Thursday, August 18, 2022 |
| APPL NO | 17/890970 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/3401 (20130101) A61B 17/3403 (20130101) Original (OR) Class A61B 2090/064 (20160201) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/427 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230068000 | DANNEMILLER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Karen DANNEMILLER (Columbus, Ohio); Rongjun QIN (Powell, Ohio); Jonathan PARQUETTE (Hilliard, Ohio); Pelagia-Irene GOUMA (Columbus, Ohio) |
| ABSTRACT | Colorimetric sensors for the detection of contaminants are described herein. In some implementations, the contaminant is formaldehyde. In other implementations, the contaminant is an allergen. Systems and methods for measuring contaminant concentration are also described herein. The colorimetric sensors described herein can be included in or used by disclosed systems and methods. Additionally, the systems and methods described herein can measure the concentration of the contaminant in an indoor environment using the colorimetric sensors. |
| FILED | Wednesday, January 13, 2021 |
| APPL NO | 17/792602 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/783 (20130101) Original (OR) Class G01N 31/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230068437 | Narayanan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Arvind Narayanan (Maple Grove, Minnesota); Eman Ramadan (Riverside, California); Feng Qian (Minneapolis, Minnesota); Zhi-Li Zhang (Eden Prairie, Minnesota) |
| ABSTRACT | A system and method for predicting one or more cellular performance parameters associated with user equipment (UE) within a three-dimensional (3D) space having one or more cellular nodes, the cellular nodes including one or more cellular nodes, including a 5G cellular node. For each of one or more of pieces of UE within the 3D space, determine values associated with one or more UE-side features of each piece of UE. Predict values of the one or more cellular performance parameters for each UE as a function of the values associated with the one or more UE-side features of each respective piece of UE, wherein predicting values of the one or more cellular performance parameters includes applying the values determined for each respective piece of UE to a machine learning module trained using truth data associated with the one or more UE-side features. |
| FILED | Thursday, August 18, 2022 |
| APPL NO | 17/820833 |
| CURRENT CPC | Wireless Communication Networks H04W 24/02 (20130101) Original (OR) Class H04W 24/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230068750 | Lou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee) |
| ASSIGNEE(S) | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee) |
| INVENTOR(S) | Jinchao Lou (Knoxville, Tennessee); Jennifer Schuster (Knoxville, Tennessee); Francisco Nicolas Barrera Olivares (Knoxville, Tennessee); Michael Douglas Best (Knoxville, Tennessee) |
| ABSTRACT | Dimer and monomer molecules according to general formulas (I) or (II) are useful as lipid switch molecules when incorporated into a membrane of a liposome. wherein R1 is a hydrophobic tail having at least 6 carbons and wherein R2 is selected from the group consisting of —NH2, wherein, for the dimer, the linker is a saturated carbon chain having 2 to 6 carbons or is a para-xylene linker; and when R2 is charged anions are present to render the charge neutral. These molecules can bind ATP or similar small phosphorylated molecules between R2 groups, which changes the shape of the molecule or the molecules orientation within the membrane thereby acting as a “switch” to release a therapeutic agent from the liposome. |
| FILED | Monday, August 01, 2022 |
| APPL NO | 17/878467 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1273 (20130101) A61K 9/1277 (20130101) A61K 31/704 (20130101) A61K 47/58 (20170801) A61K 47/6925 (20170801) Original (OR) Class A61K 47/6935 (20170801) A61K 49/0084 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/88 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230068803 | HEIKENFELD et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF CINCINNATI (CINCINNATI, Ohio); MFB FERTILITY, INC. (BOULDER, Colorado) |
| ASSIGNEE(S) | UNIVERSITY OF CINCINNATI (CINCINNATI, Ohio); MFB FERTILITY, INC. (BOULDER, Colorado) |
| INVENTOR(S) | Jason HEIKENFELD (Cincinnati, Ohio); Amy BECKLEY (Erie, Colorado) |
| ABSTRACT | Provided herein are devices and methods for monitoring biofluids related to ovulation. Such devices include the use of electrochemical aptamer-based (EAB) sensors. |
| FILED | Saturday, August 27, 2022 |
| APPL NO | 17/822773 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/6801 (20130101) A61B 5/14514 (20130101) A61B 10/0012 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/76 (20130101) Original (OR) Class G01N 33/493 (20130101) G01N 2333/59 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230068989 | Zeng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of South Carolina (Columbia, South Carolina) |
| ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
| INVENTOR(S) | Qiang Zeng (West Columbia, South Carolina); Lannan Luo (West Columbia, South Carolina) |
| ABSTRACT | Described herein are methods, techniques and systems for a user to conduct authentication via inertial measurement unit data collected by the user's smartphone and video data collected by a drone recording the user operations for mutual authentication, as well as to prevent attacks of the authentication data, wherein correlation can be easily extended to using other information, such as noises, illuminance, GPS, and how the phone flashlight flashes. |
| FILED | Thursday, June 30, 2022 |
| APPL NO | 17/854060 |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0832 (20130101) Wireless Communication Networks H04W 12/06 (20130101) Original (OR) Class H04W 12/0431 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20230061174 | HONG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Obsidian Sensors, Inc. (San Diego, California) |
| ASSIGNEE(S) | Obsidian Sensors, Inc. (San Diego, California) |
| INVENTOR(S) | John HONG (San Diego, California); Tallis CHANG (San Diego, California); Bing WEN (San Diego, California); Edward CHAN (San Diego, California); Sean ANDREWS (San Diego, California); Heesun SHIN (San Diego, California) |
| ABSTRACT | Microelectromechanical system (MEMS) devices, methods of operating the MEMS device, and methods of manufacturing the MEMS device are disclosed. In some embodiments, the MEMS device includes a glass substrate; an electrode on the glass substrate; a hinge mechanically coupled to the electrode; a membrane mirror mechanically coupled to the hinge; a TFT on the glass substrate and electrically coupled to the electrode; and a control circuit comprising: a multiplexer configured to turn on or turn off the TFT; and a drive source configured to provide a drive signal for charging the electrode through the TFT. An amplitude of the drive signal corresponds to an amount of charge, and the amount of charge generates an electrostatic force for actuating the hinge and a portion of the membrane mirror mechanically coupled to the hinge. In some embodiments, the MEMS devices comprise a charge transfer circuit for providing the amount of charge. |
| FILED | Friday, August 26, 2022 |
| APPL NO | 17/896978 |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 7/02 (20130101) Original (OR) Class B81B 2201/042 (20130101) B81B 2203/04 (20130101) B81B 2203/0127 (20130101) B81B 2203/0163 (20130101) B81B 2203/0353 (20130101) B81B 2207/01 (20130101) B81B 2207/03 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00015 (20130101) B81C 2201/0135 (20130101) B81C 2201/0156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230064980 | HOWE |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HOWE INDUSTRIES LLC (SCOTTSDALE, Arizona) |
| ASSIGNEE(S) | HOWE INDUSTRIES LLC (SCOTTSDALE, Arizona) |
| INVENTOR(S) | Troy HOWE (Scottsdale, Arizona) |
| ABSTRACT | A thermoelectric cooler including a thermoelectric junction and a radiation source. The thermoelectric cooler includes n-type material, p-type material, and an electrical power source. The radiation source emits ionizing radiation that increases electrical conductivity of the n and p type materials. Also detailed is a method of using radiation to reach high coefficient of performance (COP) values with a thermoelectric cooler that includes providing a thermoelectric cooler and a radiation source, with the thermoelectric cooler including an n-type material, p-type material, an electrical power source, and emitting ionizing radiation with the radiation source to increase the electrical conductivity which strips electrons from the n-type material, the p-type material, or both the n-type material and p-type material from their nuclei with the electrons then free to move within the material. |
| FILED | Thursday, October 13, 2022 |
| APPL NO | 18/046199 |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/16 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/26 (20130101) H01L 35/30 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230065211 | KOZUBAL et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Fynder Group, Inc. (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark A. KOZUBAL (Bozeman, Montana); Richard E. MACUR (Manhattan, Montana); Yuval C. AVNIEL (Missoula, Montana); Maximilian DeVane HAMILTON (Bozeman, Montana) |
| ABSTRACT | Methods of production of edible filamentous fungal biomat formulations are provided as standalone protein sources and/or protein ingredients in foodstuffs as well as a one-time use or repeated use self-contained biofilm-biomat reactor comprising a container with at least one compartment and placed within the compartment(s), a feedstock, a fungal inoculum, a gas-permeable membrane, and optionally a liquid nutrient medium. |
| FILED | Tuesday, October 04, 2022 |
| APPL NO | 17/959495 |
| CURRENT CPC | Dairy Products, e.g Milk, Butter, Cheese; Milk or Cheese Substitutes; Making Thereof A23C 9/1203 (20130101) Cocoa; Cocoa Products, e.g Chocolate; Substitutes for Cocoa or Cocoa Products; Confectionery; Chewing Gum; Ice-cream; Preparation Thereof A23G 9/36 (20130101) Protein Compositions for Foodstuffs; Working-up Proteins for Foodstuffs; Phosphatide Compositions for Foodstuffs A23J 3/20 (20130101) A23J 3/227 (20130101) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 29/065 (20160801) A23L 31/00 (20160801) Original (OR) Class A23L 33/195 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) A23V 2250/208 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/00 (20130101) C12M 23/24 (20130101) C12M 23/34 (20130101) C12M 23/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/14 (20130101) C12N 1/145 (20210501) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/77 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230065517 | Kochergin |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vladimir Kochergin (Christiansburg, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vladimir Kochergin (Christiansburg, Virginia) |
| ABSTRACT | The present invention relates to charged particle, X-ray, gamma ray and or thermal neutron collimators with improved UV, visible and IR blocking on the basis of micro structured semiconductor and method of making the same. In more detail, the present invention is related to three-dimensionally microstructured charged particle, X-ray, gamma ray and or thermal neutron collimators. The collimators of the present invention will improve the performance of telescopes, radiology equipment, nondestructive evaluation equipment and proton therapy equipment. |
| FILED | Monday, August 30, 2021 |
| APPL NO | 17/460721 |
| CURRENT CPC | Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/025 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230069366 | MISTRY et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | KALSI ENGINEERING, INC. (Sugar Land, Texas) |
| ASSIGNEE(S) | KALSI ENGINEERING, INC. (Sugar Land, Texas) |
| INVENTOR(S) | Mital Chandrakant MISTRY (Richmond, Texas); Zachary W. LEUTWYLER (Richmond, Texas); Aaron P. RICHIE (Missouri City, Texas); Manmohan S. KALSI (Houston, Texas) |
| ABSTRACT | A passive thermal control valve comprising a thermal actuator coupled to a valve body having first and second ports. The thermal actuator including an actuator body having an inner bore. An adjustment stop engages the actuator body. A cylinder is received within the actuator body inner bore and the cylinder has a cylinder bore open at one end. An actuator spring within the actuator body biases the cylinder towards the adjustment stop. An actuator rod is at least partially received within the cylinder and has first and second ends. At least a portion of the actuator rod is allowed to extend through the open cylinder bore. A sealing element forms a seal between the actuator rod and the cylinder and defines a sealed chamber within the cylinder. A thermal fluid is contained within the cylinder. A lever mechanism is connected to the valve body and includes a lever having a first end connected to the valve body. A valve spool is connected to a lever second end. The valve spool is arranged and designed to close the first port and allow a system fluid to flow through the second port, close the second port and allow the system fluid to flow through the first port, or allow the system fluid to flow through both the first and second ports. |
| FILED | Monday, August 29, 2022 |
| APPL NO | 17/898204 |
| CURRENT CPC | Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 31/002 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 7/0126 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20230061715 | SCHELLENBERGER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Amunix Pharmaceuticals, Inc. (South San Francisco, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Volker SCHELLENBERGER (Palo Alto, California); Joshua SILVERMAN (Los Altos Hills, California); Chia-wei WANG (Santa Clara, California); Benjamin SPINK (San Carlos, California); Willem P.C STEMMER (Los Gatos, California); Nathan C. GEETHING (Santa Clara, California) |
| ABSTRACT | The present invention relates to binding fusion protein compositions comprising targeting moieties linked to extended recombinant polypeptide (XTEN), binding fusion protein-drug conjugate compositions, and XTEN-drug conjugate compositions, isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of diseases, disorders, and conditions. |
| FILED | Thursday, February 24, 2022 |
| APPL NO | 17/680070 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/00 (20130101) C07K 14/7155 (20130101) C07K 14/8125 (20130101) C07K 14/70521 (20130101) C07K 16/18 (20130101) C07K 16/32 (20130101) C07K 16/40 (20130101) C07K 16/241 (20130101) C07K 16/244 (20130101) C07K 16/2809 (20130101) C07K 16/2863 (20130101) C07K 16/2878 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/625 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230065211 | KOZUBAL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Fynder Group, Inc. (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark A. KOZUBAL (Bozeman, Montana); Richard E. MACUR (Manhattan, Montana); Yuval C. AVNIEL (Missoula, Montana); Maximilian DeVane HAMILTON (Bozeman, Montana) |
| ABSTRACT | Methods of production of edible filamentous fungal biomat formulations are provided as standalone protein sources and/or protein ingredients in foodstuffs as well as a one-time use or repeated use self-contained biofilm-biomat reactor comprising a container with at least one compartment and placed within the compartment(s), a feedstock, a fungal inoculum, a gas-permeable membrane, and optionally a liquid nutrient medium. |
| FILED | Tuesday, October 04, 2022 |
| APPL NO | 17/959495 |
| CURRENT CPC | Dairy Products, e.g Milk, Butter, Cheese; Milk or Cheese Substitutes; Making Thereof A23C 9/1203 (20130101) Cocoa; Cocoa Products, e.g Chocolate; Substitutes for Cocoa or Cocoa Products; Confectionery; Chewing Gum; Ice-cream; Preparation Thereof A23G 9/36 (20130101) Protein Compositions for Foodstuffs; Working-up Proteins for Foodstuffs; Phosphatide Compositions for Foodstuffs A23J 3/20 (20130101) A23J 3/227 (20130101) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 29/065 (20160801) A23L 31/00 (20160801) Original (OR) Class A23L 33/195 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) A23V 2250/208 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/00 (20130101) C12M 23/24 (20130101) C12M 23/34 (20130101) C12M 23/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/14 (20130101) C12N 1/145 (20210501) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/77 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230066556 | HERRINGTON et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Voxel Innovations, Inc. (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel HERRINGTON (Raleigh, North Carolina); Eric ROUNTREE (Raleigh, North Carolina) |
| ABSTRACT | A discretized-flow electrode for use in electrochemical machining (ECM) and a corresponding method and system for using the discretized-flow cathode are disclosed. The machining face of the discretized-flow cathode is divided into a plurality of discrete sections. The discrete sections may be geometrically shaped, and they are separated at the machining face by an electrolyte flow outlet channel, and each discrete section includes an electrolyte flow inlet local to the discrete section. The plurality of discrete sections of the machining face of the discretized-flow electrode divide the electrolyte flow into approximately equal portions for even electrolyte flow across the machining face. |
| FILED | Thursday, October 20, 2022 |
| APPL NO | 18/048273 |
| CURRENT CPC | Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 5/08 (20130101) C25D 17/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230068006 | Alexander |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | DayLyte, Inc. (Knoxville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Caleb Tyler Alexander (Knoxville, Tennessee) |
| ABSTRACT | Methods of improving an aqueous metal-air battery are disclosed. The methods include forming a solid electrolyte on a conductive substrate; forming a protective surface on the solid electrolyte; having and improving separate oxygen reduction and oxygen evolution electrodes; improving the gas diffusion of the oxygen reduction and evolution electrodes; and improving the structure of the battery cell. Improved metal-air batteries including such improvements are further disclosed. |
| FILED | Thursday, September 01, 2022 |
| APPL NO | 17/901358 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 12/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20230067015 | EBRAHIMI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Seyedehaida EBRAHIMI (University Park, Pennsylvania); Chen ZHOU (University Park, Pennsylvania); Jasna KOVAC (University Park, Pennsylvania); Zhiwen LIU (University Park, Pennsylvania); Keren ZHOU (University Park, Pennsylvania) |
| ABSTRACT | A method for antibacterial susceptibility testing includes preparing a set of two or more samples of a plurality of bacterial cells from a patient; adding a different amount of a selected drug to each sample; illuminating at least a portion of a sample using a coherent illumination source; capturing a series of speckle images over time of at least a portion of the illuminated sample; and determining an inhibition status of the sample using a machine-learning classifier applied to the series of speckle images. The steps of illuminating the sample, capturing a series of images, and determining an inhibition status are repeated for each sample of the set of two or more samples. The method may include transforming the series of speckle images to a frequency series of speckle images; and determining the inhibition status of the sample uses the machine-learning classifier applied to the frequency series of speckle images. |
| FILED | Wednesday, February 03, 2021 |
| APPL NO | 17/759995 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/4788 (20130101) G01N 2021/479 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230067609 | White et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey); U.S. GEOLOGICAL SURVEY (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James F. White (South River, New Jersey); Kurt P. Kowalski (Ann Arbor, Michigan); Kathryn L. Kingsley (Robbinsville, New Jersey); Matthew T. Elmore (East Brunswick, New Jersey); Xiaoqian Chang (Piscataway, New Jersey) |
| ABSTRACT | Endophytic bacteria, compositions comprising the same, and methods of use thereof are disclosed which suppress growth of aggressive, invasive weed species which grow in the same habitat of target plants of interest. Bioherbicides, compositions comprising the endophytic bacteria and methods of use thereof are disclosed which suppress growth of aggressive, invasive weed species which grow in the same habitat of target plants of interest. |
| FILED | Wednesday, July 27, 2022 |
| APPL NO | 17/815435 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/04 (20130101) A01N 47/44 (20130101) A01N 63/20 (20200101) A01N 63/22 (20200101) A01N 63/25 (20200101) A01N 63/27 (20200101) A01N 63/30 (20200101) Original (OR) Class A01N 65/36 (20130101) Biocidal, Pest Repellant, Pest Attractant or Plant Growth Regulatory Activity of Chemical Compounds or Preparations A01P 13/02 (20210801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 20230060711 | Bertness et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kristine Ann Bertness (Boulder, Colorado); Matthew David Brubaker (Louisville, Colorado); Patrick John Fay (Granger, Indiana) |
| ABSTRACT | A core-shell nanofin vertical switch performs high-voltage switching and includes: an n-type GaN nanofin core including: an n-type drift layer; an n-type channel; and an n-type source; a p-type nanofin shell surrounding the n-type GaN nanofin core at an interface surface of the n-type GaN nanofin core, and comprising GaN; an optional source contact disposed on the n-type GaN nanofin core and the p-type nanofin shell and in electrical communication with the n-type source, such that the n-type source is interposed between the source contact and the n-type channel; and a gate contact disposed on the p-type nanofin shell and in electrical communication with the p-type nanofin shell, such that the p-type nanofin shell is interposed between the gate contact and the n-type channel, and the gate contact is interposed between the source contact and a drain contact. |
| FILED | Wednesday, August 24, 2022 |
| APPL NO | 17/821977 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/205 (20130101) H01L 29/0634 (20130101) H01L 29/2003 (20130101) H01L 29/7788 (20130101) Original (OR) Class H01L 29/66462 (20130101) Pulse Technique H03K 17/6871 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230065149 | Hersam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark C. Hersam (Wilmette, Illinois); Woo Jin Hyun (Shantou, China PRC); Lindsay E. Chaney (Evanston, Illinois) |
| ABSTRACT | One aspect of the invention relates to an ionogel electrolyte ink including an ionic liquid; and a gelling matrix material. The gelling matrix material is mixed with the ionic liquid in at least one solvent. |
| FILED | Tuesday, October 18, 2022 |
| APPL NO | 17/968180 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/623 (20130101) H01M 4/625 (20130101) H01M 10/0525 (20130101) H01M 10/0565 (20130101) Original (OR) Class H01M 10/0585 (20130101) H01M 2004/027 (20130101) H01M 2300/0082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20230061121 | TOSEVSKA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SIEMENS AKTIENGESELLSCHAFT (München, Germany) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); United States Government Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Anela TOSEVSKA (Los Angeles, California); Matteo PELLEGRINI (Los Angeles, California); Marilene WANG (Los Angeles, California); Eri SRIVATSAN (Los Angeles, California); Marco MORSELLI (Loa Angeles, California) |
| ABSTRACT | A system for industrial application package management includes a computing device having a processor and a memory having executable programs and applications stored thereon, including plurality of industrial application programs miming an engineering project involving multiple different disciplines, and a package manager client. The package manager client communicates with a remote repository server that hosts application packages, and sends requests for packages and receives package deliveries. The package manager client unbundles package metainformation relevant to a domain specific application and according to an industrial package information schema. A dependency tracking module identifies dependencies of a current package to other packages and generates a dependency tree that includes the name and version of each dependent package. An upgrade analyzer compares dependency trees to identify dependency incompatibilities as conflicting packages based on inconsistencies and performs an automated resolution of the dependency incompatibilities. |
| FILED | Friday, May 15, 2020 |
| APPL NO | 17/609985 |
| CURRENT CPC | Electric Digital Data Processing G06F 8/61 (20130101) Original (OR) Class G06F 21/577 (20130101) G06F 2221/033 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230065466 | Callahan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Deanna Callahan (Loma Linda, California); Shane M Elliot (Loma Linda, California); Robert Durkin (Washington, District of Columbia) |
| ABSTRACT | A method may comprise determining, based on a date, a patient identified for a patient scheduled for an appointment, determining, based on the patient identifier, a mobile device number associated with the patient, sending, based on the mobile device number, an interactive message, and receiving, in response to the interactive message, an indication that the appointment should be maintained or canceled. |
| FILED | Monday, October 05, 2020 |
| APPL NO | 17/766415 |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/1095 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 40/20 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 20230067609 | White et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey); U.S. GEOLOGICAL SURVEY (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James F. White (South River, New Jersey); Kurt P. Kowalski (Ann Arbor, Michigan); Kathryn L. Kingsley (Robbinsville, New Jersey); Matthew T. Elmore (East Brunswick, New Jersey); Xiaoqian Chang (Piscataway, New Jersey) |
| ABSTRACT | Endophytic bacteria, compositions comprising the same, and methods of use thereof are disclosed which suppress growth of aggressive, invasive weed species which grow in the same habitat of target plants of interest. Bioherbicides, compositions comprising the endophytic bacteria and methods of use thereof are disclosed which suppress growth of aggressive, invasive weed species which grow in the same habitat of target plants of interest. |
| FILED | Wednesday, July 27, 2022 |
| APPL NO | 17/815435 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/04 (20130101) A01N 47/44 (20130101) A01N 63/20 (20200101) A01N 63/22 (20200101) A01N 63/25 (20200101) A01N 63/27 (20200101) A01N 63/30 (20200101) Original (OR) Class A01N 65/36 (20130101) Biocidal, Pest Repellant, Pest Attractant or Plant Growth Regulatory Activity of Chemical Compounds or Preparations A01P 13/02 (20210801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230069692 | Sicking et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sicking Safety Systems LLC (Indian Springs Village, Alabama) |
| ASSIGNEE(S) | Sicking Safety Systems LLC (Indian Springs Village, Alabama) |
| INVENTOR(S) | Dean L. Sicking (Indian Springs Village, Alabama); Dakotah Sicking (Keller, Texas); Steven D. Thompson (Bessemer, Alabama); Kenneth Walls (Trussville, Alabama); Kevin D. Schrum (Pelham, Alabama); Joseph Schwertz (Birmingham, Alabama); David Littlefield (Vestavia Hills, Alabama); Andrew Dameron (Birmingham, Alabama) |
| ABSTRACT | Guardrail, guardrail terminal, and support post designs that improve control of a vehicle during collisions are described. The disclosed designs also reduce the likelihood of intrusion into vehicle systems and the occupant compartment(s). Embodiments include folding and/or flattening of the guardrail and controlling the folded and flattened guardrail to avoid intrusion into the vehicle. Other embodiments include containing the guardrail in an impact head of a guardrail terminal, which also avoids vehicle intrusion. |
| FILED | Friday, October 07, 2022 |
| APPL NO | 18/045060 |
| CURRENT CPC | Additional Work, Such as Equipping Roads or the Construction of Platforms, Helicopter Landing Stages, Signs, Snow Fences, or the Like E01F 15/143 (20130101) Original (OR) Class E01F 15/0423 (20130101) E01F 15/0461 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Classified Government Agency
| US 20230066240 | Reven et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Shawn C. Reven (Greenlawn, New York); Daniel Engheben (Commack, New York); Jacinto E. Malabuyoc (Holbrook, New York) |
| ABSTRACT | A Mid-Wave Infrared (MWIR) objective and relay lens system has an F# of 3.33 and angular field of view of 15.28°. It is deployed, with a focal plane and scanning system, on airborne platforms for wide area motion imagery. It is corrected for monochromatic and chromatic aberrations over of 3.3 to 5.1 micrometers. Effective focal length is 20 inches, and the overall length is 40.70 inches. The lens has, from object to image, two groups of optical elements with a cold shield/aperture stop 6 inches from the image plane. Group 1 acts as an objective lens with a positive power and three elements, Group 2 acts as a relay lens has a positive power and four elements. The lens is made of Germanium and Silicon. It used in a scanning system in a pre-objective configuration where the fast scan mirror is located in front of the lens system. |
| FILED | Monday, August 23, 2021 |
| APPL NO | 17/408537 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 13/14 (20130101) Original (OR) Class G02B 15/02 (20130101) G02B 26/10 (20130101) G02B 26/0816 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Housing and Urban Development (HUD)
| US 20230068000 | DANNEMILLER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Karen DANNEMILLER (Columbus, Ohio); Rongjun QIN (Powell, Ohio); Jonathan PARQUETTE (Hilliard, Ohio); Pelagia-Irene GOUMA (Columbus, Ohio) |
| ABSTRACT | Colorimetric sensors for the detection of contaminants are described herein. In some implementations, the contaminant is formaldehyde. In other implementations, the contaminant is an allergen. Systems and methods for measuring contaminant concentration are also described herein. The colorimetric sensors described herein can be included in or used by disclosed systems and methods. Additionally, the systems and methods described herein can measure the concentration of the contaminant in an indoor environment using the colorimetric sensors. |
| FILED | Wednesday, January 13, 2021 |
| APPL NO | 17/792602 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/783 (20130101) Original (OR) Class G01N 31/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 20230069692 | Sicking et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sicking Safety Systems LLC (Indian Springs Village, Alabama) |
| ASSIGNEE(S) | Sicking Safety Systems LLC (Indian Springs Village, Alabama) |
| INVENTOR(S) | Dean L. Sicking (Indian Springs Village, Alabama); Dakotah Sicking (Keller, Texas); Steven D. Thompson (Bessemer, Alabama); Kenneth Walls (Trussville, Alabama); Kevin D. Schrum (Pelham, Alabama); Joseph Schwertz (Birmingham, Alabama); David Littlefield (Vestavia Hills, Alabama); Andrew Dameron (Birmingham, Alabama) |
| ABSTRACT | Guardrail, guardrail terminal, and support post designs that improve control of a vehicle during collisions are described. The disclosed designs also reduce the likelihood of intrusion into vehicle systems and the occupant compartment(s). Embodiments include folding and/or flattening of the guardrail and controlling the folded and flattened guardrail to avoid intrusion into the vehicle. Other embodiments include containing the guardrail in an impact head of a guardrail terminal, which also avoids vehicle intrusion. |
| FILED | Friday, October 07, 2022 |
| APPL NO | 18/045060 |
| CURRENT CPC | Additional Work, Such as Equipping Roads or the Construction of Platforms, Helicopter Landing Stages, Signs, Snow Fences, or the Like E01F 15/143 (20130101) Original (OR) Class E01F 15/0423 (20130101) E01F 15/0461 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Interior (DOI)
| US 20230067609 | White et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey); U.S. GEOLOGICAL SURVEY (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James F. White (South River, New Jersey); Kurt P. Kowalski (Ann Arbor, Michigan); Kathryn L. Kingsley (Robbinsville, New Jersey); Matthew T. Elmore (East Brunswick, New Jersey); Xiaoqian Chang (Piscataway, New Jersey) |
| ABSTRACT | Endophytic bacteria, compositions comprising the same, and methods of use thereof are disclosed which suppress growth of aggressive, invasive weed species which grow in the same habitat of target plants of interest. Bioherbicides, compositions comprising the endophytic bacteria and methods of use thereof are disclosed which suppress growth of aggressive, invasive weed species which grow in the same habitat of target plants of interest. |
| FILED | Wednesday, July 27, 2022 |
| APPL NO | 17/815435 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/04 (20130101) A01N 47/44 (20130101) A01N 63/20 (20200101) A01N 63/22 (20200101) A01N 63/25 (20200101) A01N 63/27 (20200101) A01N 63/30 (20200101) Original (OR) Class A01N 65/36 (20130101) Biocidal, Pest Repellant, Pest Attractant or Plant Growth Regulatory Activity of Chemical Compounds or Preparations A01P 13/02 (20210801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 20230068990 | Zheng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Platefuse, Inc. (Cincinnati, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yi Zheng (Cincinnati, Ohio); Jose Cancelas (Cincinnati, Ohio) |
| ABSTRACT | Disclosed are compounds and compositions for slowing, preventing, or reversing platelet damage, particularly as may occur during blood banking or during refrigeration of platelets. Also disclosed herein are methods for storing platelets and methods for improving platelet survival upon transfusion with one or more compounds or compositions as described herein. |
| FILED | Wednesday, January 13, 2021 |
| APPL NO | 17/792864 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0226 (20130101) Original (OR) Class A01N 1/0284 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0644 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 20230065240 | White |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America As Represented By The Director Of The National Geospatial-Intelligence (Springfield, Virginia) |
| ASSIGNEE(S) | The United States of America As Represented By The Director Of The National Geospatial-Intelligence (Springfield, Virginia) |
| INVENTOR(S) | Troy White (Ashburn, Virginia) |
| ABSTRACT | A device and methods for displaying representations of objects, solids, and surfaces volumetrically in a medium containing one or more photochromic compounds comprising at least one UVA light source arranged to project a beam of UVA radiation and irradiate at least one portion of a display volume incorporating at least one display medium which includes at least one photochromic compound. The irradiance of the irradiated portion of the display medium being sufficient for clear-to-colored transitions of voxels of the display medium from a transparent state to a colored state. After a time period after the irradiation, the irradiated voxels activated in the colored state transition by a colored-to-clear transition into the transparent state. |
| FILED | Wednesday, August 25, 2021 |
| APPL NO | 17/411119 |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0126 (20130101) Pictorial Communication, e.g Television H04N 13/365 (20180501) H04N 13/388 (20180501) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, March 02, 2023.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-applications-20230302.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page