FedInvent™ Patent Applications
Application Details for Thursday, March 16, 2023
This page was updated on Thursday, March 16, 2023 at 11:40 AM GMT
Department of Health and Human Services (HHS)
| US 20230077412 | TANG et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | William C. TANG (Irvine, California); Andrew W. BROWNE (Newport Coast, California); Magdalene J. SEILER (Orange, California); Yuntian XUE (Irvine, California) |
| ABSTRACT | A bioreactor device includes a solid substrate having a first face and a second face. The solid substrate at least partially defines a perfusion channel, a plurality of chambers, a fluidic inlet, and a fluidic outlet. A first sheet disposed over the first face and a second sheet disposed over the second face. Characteristically, the combination of the solid substrate, the first sheet and the second sheet define the perfusion channel and each chamber of the plurality of chambers. The plurality of chambers are arranged in rows of chambers in which adjacent chambers are positioned at opposite side of the perfusion channel. The perfusion channel extends from the fluidic inlet and the fluidic outlet having a serpentine path along each row of chambers with each chamber being in fluid communication with the perfusion channel. |
| FILED | Tuesday, September 06, 2022 |
| APPL NO | 17/903458 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0247 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/062 (20130101) C12N 5/0621 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230077514 | Bohórquez |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
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| INVENTOR(S) | Diego V. Bohórquez (Cary, North Carolina) |
| ABSTRACT | Described herein are methods for modulating a transsynaptic signal through a neuroepithelial circuit between a gut sensory cell and the brain, as well as methods that involve modulating a transsynaptic signal through a neuroepithelial circuit between a gut sensory cell and the brain. In one aspect, the transsynaptic signal is modulated by glutamate or ATP. |
| FILED | Wednesday, February 17, 2021 |
| APPL NO | 17/798417 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/165 (20130101) A61B 5/4017 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) A61K 31/662 (20130101) A61K 31/675 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230077716 | Ellebedy |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
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| INVENTOR(S) | Ali Ellebedy (St. Louis, Missouri) |
| ABSTRACT | The present invention relates to antibodies or antigen-binding fragments that are useful for treating influenza B viruses. The present invention also relates to various pharmaceutical compositions and methods of treating influenza using the antibodies or antigen-binding fragments. |
| FILED | Friday, February 05, 2021 |
| APPL NO | 17/798261 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/16 (20180101) Peptides C07K 16/1018 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/33 (20130101) C07K 2317/34 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230077811 | HAMRAH et al. |
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| FUNDED BY |
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| APPLICANT(S) | Tufts Medical Center, Inc. (Boston, Massachusetts); Trustees of Tufts College (Medford, Massachusetts) |
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| INVENTOR(S) | Pedram HAMRAH (Wellesley, Massachusetts); Abdo ABOU-SLAYBI (Worcester, Massachusetts) |
| ABSTRACT | The invention relates to methods and compositions for use in the treatment and prevention of ocular diseases or conditions associated with neovascularization and/or inflammation. |
| FILED | Thursday, February 11, 2021 |
| APPL NO | 17/798344 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0048 (20130101) A61K 31/454 (20130101) Original (OR) Class A61K 38/33 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230077821 | Segal et al. |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rosalind Segal (Brookline, Massachusetts); Loren D. Walensky (Newton, Massachusetts); Lisa V. Goodrich (Newton, Massachusetts); Sarah Elizabeth Raissi (Waltham, Massachusetts); Maria F. Murphy (Revere, Massachusetts); Gregory H. Bird (Pelham, New Hampshire) |
| ABSTRACT | Compositions and methods are provided for the treatment or prevention of chemotherapy-induced peripheral neuropathy and hearing loss in a subject in need thereof. The methods involve administering to the subject a bclw protein, a BH4 domain-containing fragment thereof, or a bclw mimetic. Also provided are exemplary bclw mimetics. |
| FILED | Monday, August 29, 2022 |
| APPL NO | 17/823018 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 38/00 (20130101) A61K 38/10 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/02 (20180101) A61P 35/00 (20180101) Peptides C07K 7/08 (20130101) C07K 14/4747 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230078007 | WILLIAMS et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
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| INVENTOR(S) | Jasper Z. WILLIAMS (San Franisco, California); Devan SHAH (San Franisco, California); Wendell A. LIM (San Francisco, California) |
| ABSTRACT | Provided herein is an in-series synthetic receptor circuit for dual-antigen AND-gate control over expression of a therapeutic payload by engineered cells. In some embodiments, the circuit may be composed of a first binding-triggered transcriptional switch, a second binding-triggered transcriptional switch and a therapeutic payload (e.g., a chimeric antigen receptor), where binding of the first binding-triggered transcriptional switch to a first antigen activates expression of the second binding-triggered transcriptional switch, and binding of the second binding-triggered transcriptional switch to a second antigen activates expression of the therapeutic payload. If the cell is an immune cell and the therapeutic payload is a chimeric antigen receptor, then the immune cell may be activated by binding of the chimeric antigen receptor to a third antigen. Methods of treatment using the cell also provided. |
| FILED | Friday, February 19, 2021 |
| APPL NO | 17/800872 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/15 (20130101) A61K 35/17 (20130101) Original (OR) Class A61K 38/19 (20130101) A61K 38/48 (20130101) A61K 38/446 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7051 (20130101) C07K 16/32 (20130101) C07K 16/2803 (20130101) C07K 16/2818 (20130101) C07K 16/2827 (20130101) C07K 2317/622 (20130101) C07K 2319/03 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 9/22 (20130101) C12N 9/0089 (20130101) C12N 15/11 (20130101) C12N 15/625 (20130101) C12N 2310/20 (20170501) C12N 2800/80 (20130101) C12N 2840/00 (20130101) Enzymes C12Y 115/01001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230078089 | Alexanian et al. |
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| APPLICANT(S) | THE J. DAVID GLADSTONE INSTITUTES, A TESTAMENTARY TRUST UNDER THE WILL OF J. DAVID GLADSTONE (San Francisco, California); The Regents of the University of California (Oakland, California) |
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| INVENTOR(S) | Michael Alexanian (San Francisco, California); Arun Padmanabhan (Oakland, California); Deepak Srivastava (San Francisco, California) |
| ABSTRACT | Described herein are methods for treating cardiac conditions that include modulating Meox1 enhancer activity, Meox1 transcription, Meox1 translation, MEOX1 protein function, or a combination thereof. Also described herein are methods for identifying agents that can modulate Meox1 enhancer activity. |
| FILED | Tuesday, March 02, 2021 |
| APPL NO | 17/799851 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230078265 | Liu et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David R. Liu (Cambridge, Massachusetts); Andrew Vito Anzalone (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure provides compositions and methods for conducting prime editing of a target DNA molecule (e.g., a genome) that enables the incorporation of a nucleotide change and/or targeted mutagenesis. The nucleotide change can include a single-nucleotide change (e.g., any transition or any transversion), an insertion of one or more nucleotides, or a deletion of one or more nucleotides. More in particular, the disclosure provides fusion proteins comprising nucleic acid programmable DNA binding proteins (napDNAbp) and a polymerase (e.g., reverse transcriptase), which is guided to a specific DNA sequence by a modified guide RNA, named an PEgRNA. The PEgRNA has been altered (relative to a standard guide RNA) to comprise an extended portion that provides a DNA synthesis template sequence which encodes a single strand DNA flap, which is homologous to a strand of the targeted endogenous DNA sequence to be edited, but which contains the desired one or more nucleotide changes and which, following synthesis by the polymerase (e.g., reverse transcriptase), becomes incorporated into the target DNA molecule. Also disclosed herein are various methods that leverage prime editing, including treating trinucleotide repeat contraction diseases, installing targeted peptide tags, treating prion disease through the installation of protection mutations, manipulating RNA-encoding genes for the installation of RNA tags for controlling the function and expression of RNA, using prime editing to construct sophisticated gene libraries, using prime editing to insert immunoepitopes into proteins, use of prime editing to insert inducible dimerization domains into protein targets, and delivery methods, among others. |
| FILED | Thursday, March 19, 2020 |
| APPL NO | 17/440682 |
| CURRENT CPC | Peptides C07K 14/001 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/1276 (20130101) C12N 15/11 (20130101) C12N 15/62 (20130101) Original (OR) Class C12N 15/902 (20130101) C12N 2310/20 (20170501) C12N 2310/3517 (20130101) C12N 2800/80 (20130101) Enzymes C12Y 207/07049 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230078590 | BAPAT et al. |
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| FUNDED BY |
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| APPLICANT(S) | Salk Institute for Biological Studies (La Jolla, California) |
| ASSIGNEE(S) | Salk Institute for Biological Studies (La Jolla, California) |
| INVENTOR(S) | Sagar P. BAPAT (La Jolla, California); Ye ZHENG (La Jolla, California); Ronald EVANS (La Jolla, California); Michael DOWNES (La Jolla, California); Annette R. ATKINS (La Jolla, California); Ruth T. YU (La Jolla, California) |
| ABSTRACT | The invention features compositions and methods treating or preventing for age-related insulin resistance, type 2 diabetes and related disorders. The method involves depleting fTreg cells with an anti-ST2 antibody to decrease age-related fTreg accumulation and restore insulin sensitivity, thereby treating age-related insulin resistance, type 2 diabetes and related disorders. |
| FILED | Tuesday, July 19, 2022 |
| APPL NO | 17/813383 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/395 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) Peptides C07K 16/28 (20130101) C07K 16/2866 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6883 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) G01N 33/6869 (20130101) Original (OR) Class G01N 2333/7155 (20130101) G01N 2800/042 (20130101) G01N 2800/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230078745 | Arboleda-Velasquez |
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| APPLICANT(S) | The Schepens Eye Research Institute, Inc. (Boston, Massachusetts) |
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| INVENTOR(S) | Joseph F. Arboleda-Velasquez (Newton, Massachusetts) |
| ABSTRACT | The present subject matter provides, inter alia, compositions, systems, kits, and methods for diagnosing and treating small vessel diseases (SVDs). |
| FILED | Tuesday, November 22, 2022 |
| APPL NO | 17/992529 |
| CURRENT CPC | Peptides C07K 16/28 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) Original (OR) Class G01N 2333/65 (20130101) G01N 2333/78 (20130101) G01N 2333/705 (20130101) G01N 2333/96433 (20130101) G01N 2800/042 (20130101) G01N 2800/56 (20130101) G01N 2800/164 (20130101) G01N 2800/2871 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230079120 | MALEK |
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| APPLICANT(S) | University of Miami (Miami, Florida) |
| ASSIGNEE(S) | University of Miami (Miami, Florida) |
| INVENTOR(S) | Thomas MALEK (Miami Beach, Florida) |
| ABSTRACT | Various methods and compositions are provided which can be employed to modulate the immune system. Compositions include a fusion protein comprising: (a) a first polypeptide comprising Interleukin-2 (IL-2) or a functional variant or fragment thereof; and (b) a second polypeptide, fused in frame to the first polypeptide, wherein the second polypeptide comprises an extracellular domain of Interleukin-2 Receptor alpha (IL-2Rα) or a functional variant or fragment thereof, and wherein the fusion protein has IL-2 activity. Various methods are provided for modulating the immune response in a subject comprising administering to a subject in need thereof a therapeutically effective amount of the IL-2/IL-2Rα fusion protein disclosed herein. |
| FILED | Thursday, August 25, 2022 |
| APPL NO | 17/822333 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/55 (20130101) Original (OR) Class C07K 14/7155 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230079439 | Chessler et al. |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, Canada); BAR-IL-AN UNIVERSITY (Ramat Gan, Israel) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven Chessler (San Diego, California); Arie Lev Gruzman (Jerusalem, Israel); Jean-Paul Lellouche (Ashdod, Israel); Anna Munder (Rishon LeZion, Israel) |
| ABSTRACT | The present invention provides compositions and methods for enhancing beta cell maturation, health and function. The invention may be used for increasing insulin secretion in a cell, promoting the formation of cell clusters, or reducing cell death. In some embodiments, the compositions and methods provide a treatment for diabetes. In some embodiments, the composition comprises an agent which increases a β-cell surface protein expression, activity or both. |
| FILED | Friday, December 08, 2017 |
| APPL NO | 16/467586 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6923 (20170801) A61K 47/6929 (20170801) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/79 (20130101) Original (OR) Class C12N 2015/8518 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230079454 | Tessier et al. |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
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| INVENTOR(S) | Shannon N. Tessier (Framingham, Massachusetts); Mustafa Korkut Uygun (Boston, Massachusetts); Heidi Yeh (Boston, Massachusetts); Mehmet Toner (Charlestown, Massachusetts); Reinier De Vries (Boston, Massachusetts) |
| ABSTRACT | Methods for monitoring the viability of a donor organ before and after transplant based on detection and analysis of whole cells released from the organs. |
| FILED | Friday, February 12, 2021 |
| APPL NO | 17/799164 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) G01N 33/56966 (20130101) Original (OR) Class G01N 2800/245 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230079737 | LaBaer et al. |
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| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona); THE U.S.A., AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
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| INVENTOR(S) | Joshua LaBaer (Chandler, Arizona); Jie Wang (Glendale, Arizona); Ji Qiu (Chandler, Arizona); Garrick Wallstrom (Mesa, Arizona); Karen Anderson (Scottsdale, Arizona); Jin Park (Phoenix, Arizona); Jonine Figueroa (Edinburgh, United Kingdom) |
| ABSTRACT | Cancer patients make antibodies to tumor-derived proteins that are potential biomarkers for early detection. Twenty-eight antigens have been identified as potential biomarkers for the early detection of basal-like breast cancer (Tables 1, 2). Also, a 13-AAb classifier has been developed that differentiate patients with BLBC from healthy controls with 33% sensitivity at 98% specificity (Table 3). |
| FILED | Thursday, September 08, 2022 |
| APPL NO | 17/940883 |
| CURRENT CPC | Peptides C07K 16/3015 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) G01N 33/57415 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230079754 | Findlay et al. |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
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| INVENTOR(S) | Andrew Findlay (St. Louis, Missouri); Conrad Weihl (St. Louis, Missouri) |
| ABSTRACT | Among the various aspects of the present disclosure is the provision of compositions and methods for selectively reducing pathogenic isoforms (e.g., DNAJB6) in a subject having a neuromuscular disorder. An aspect of the present disclosure provides for selectively reducing DNAJB6 in a subject having a neuromuscular disorder (e.g., limb-girdle muscular dystrophy D1 (LGMD-D1)) comprising administering an amount of a DNAJB6-targeting antisense oligonucleotide (ASO) sufficient to reduce the expression of DNAJB6 compared to the subject prior to being administered the DNAJB6-targeting ASO. |
| FILED | Friday, September 16, 2022 |
| APPL NO | 17/932996 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230079832 | Gazit et al. |
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| FUNDED BY |
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| APPLICANT(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| ASSIGNEE(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| INVENTOR(S) | Dan Gazit (Los Angeles, California); Debiao Li (South Pasadena, California); Gadi Pelled (Los Angeles, California); Zulma Gazit (Los Angeles, California); Zhengwei Zhou (Sherman Oaks, California) |
| ABSTRACT | In various embodiments, the invention teaches systems and methods for magnetic resonance imaging. In some embodiments, the invention teaches systems and methods for determining the source of pain in intervertebral discs by measuring one or more physiological biomarkers associated with disc pain and/or disc degeneration. |
| FILED | Monday, November 14, 2022 |
| APPL NO | 17/986396 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/4566 (20130101) Original (OR) Class A61B 5/4824 (20130101) A61B 5/7275 (20130101) A61B 5/14539 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4838 (20130101) G01R 33/5605 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230079919 | Claussen et al. |
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| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan Claussen (Ames, Iowa); Bolin Chen (San Jose, California); Carmen L. Gomes (Ames, Iowa) |
| ABSTRACT | Apparatus, systems, and methods for tuning the structure, conductivity, and/or wettability of laser induced graphene for a variety of functions including but not limited to multiplexed open microfluidic environmental biosensing and energy storage devices. Aspects of this invention introduce a one-step, mask-free process to create, pattern, and tune laser-induced graphene (LIG) with a ubiquitous CO2 laser or other laser. The laser parameters are adjusted to create LIG with different electrical conductivity, surface morphology, and surface wettability without the need for post chemical modification. This can be done with a single lasing. By optionally introducing a second (or third, fourth, or more) lasing(s), the LIG characteristics can be changed in just the same one step of using the laser scribing without other machines or sub-systems. One example is a second lasing with the same laser sub-system at low laser power, wherein the wettability of the LIG can be significantly altered. Such films presented unique superhydrophobicity owing to the combination of the micro/nanotextured structure and the removal of the hydrophilic oxygen-containing functional groups. The ability to tune the wettability of LIG while retaining high electrical conductivity and mechanical robustness allows rational design of LIG based on application. |
| FILED | Monday, September 12, 2022 |
| APPL NO | 17/931228 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 3/502715 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/351 (20151001) B23K 26/364 (20151001) Original (OR) Class B23K 26/0622 (20151001) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/36 (20130101) H01G 11/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230080204 | Ramachandra et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Abhay Bangalore Ramachandra (New Haven, Connecticut); Alison Marsden (Stanford, California); Jay Humphrey (New Haven, Connecticut); Jack Boyd (Stanford, California); Hanjay Wang (Stanford, California); Michael Paulsen (Stanford, California); Joshua Pickering (Stanford, California); Muhammad Khan (Stanford, California) |
| ABSTRACT | Adaptive graft assemblies and methods of manufacture and implantation are provided herein. In particular, such grafts can be 3D printed and can be defined as standard designs or patient-specific, external sheaths customized for specific vein graft dimensions following minimally/non-invasive vein mapping and computational modeling. The external sheath may include one or more layers of various biomaterials to produce customized biomechanical properties. The external sheath may be made to elute specific bioactive drugs allowing for pharmacologic prevention of adverse remodeling in addition to mechanical support. These customizable features may be tailored for each patient individually depending on specific medical history, including hypertension, diabetes, smoking history, anatomy or any pertinent patient attribute. These methods protect vascular grafts, specifically venous grafts, from immediate exposure to arterial pressure that can induce adverse remodeling and graft failure, thereby providing a precision medicine solution to cardiovascular bypass surgery. |
| FILED | Thursday, October 06, 2022 |
| APPL NO | 17/961489 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/07 (20130101) Original (OR) Class A61F 2210/0004 (20130101) A61F 2210/0076 (20130101) A61F 2240/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230080265 | Lai et al. |
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| FUNDED BY |
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| APPLICANT(S) | Synbal, Inc. (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | ChenYen Lai (Escondido, California); Oscar Alvarez (San Marcos, California); Kurt Jarnagin (San Mateo, California) |
| ABSTRACT | The present disclosure relates to genetically modified non-human animals (e.g., genetically-modified mice or rodents) that express a hACE2 and/or hTMPRRS2 under control of the mouse promoter and the genetically modified non-human animal does not express native ACE2 and/or hTMPRRS2. The present disclosure also relates to methods of generating the genetically-modified animals (e.g., genetically modified mice or rodents), and methods of using the genetically modified non-human animals (e.g., genetically modified mice or rodents) described herein. |
| FILED | Monday, June 27, 2022 |
| APPL NO | 17/850770 |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0278 (20130101) Original (OR) Class A01K 2207/15 (20130101) A01K 2227/105 (20130101) A01K 2267/0337 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/485 (20130101) C12N 9/6424 (20130101) C12N 15/8509 (20130101) C12N 2015/8581 (20130101) Enzymes C12Y 304/17023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230080312 | Marcus et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Oregon (Eugene, Oregon) |
| ASSIGNEE(S) | University of Oregon (Eugene, Oregon) |
| INVENTOR(S) | Andrew H. Marcus (Eugene, Oregon); Claire S. Albrecht (Eugene, Oregon); John W. Maurer (Eugene, Oregon); Patrick J. Herbert (Eugene, Oregon); Dylan Heussman (Eugene, Oregon) |
| ABSTRACT | Swept polarization optical beams are directed to a sample to produce fluorescence. typical as a plurality of single photon detection events. Based on frequencies associated with the polarization sweeps, orientation of a sample can be determined. Using polarization sweeps at first and second frequencies and wavelength, donor fluorophore orientation can be established based on the first frequency and wavelength and acceptor orientation can be established based on a sum or difference of the first and second frequencies and the second wavelength. |
| FILED | Tuesday, September 13, 2022 |
| APPL NO | 17/931870 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6408 (20130101) G01N 21/6428 (20130101) G01N 21/6445 (20130101) Original (OR) Class G01N 21/6458 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230080350 | NADKARNI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York); RENALYTIX AI PLC (Penarth, Cardiff, United Kingdom) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Girish N. NADKARNI (New York, New York); Steven G. COCA (New York, New York); Fergus FLEMING (Penarth, Cardiff, United Kingdom) |
| ABSTRACT | In some embodiments, a non-transitory processor-readable medium can store code to be executed by a processor of a first compute device. The code can include code to cause the processor to receive, from a second compute device remote from the first compute device, a trained machine learning model. The code can include code to cause the processor to receive biomarker data and HSD of a diabetic human subject. The biomarker data can indicate a level of at least one of the following biomarkers: sTNFR-1, sTNFR-2, KIM-1, and ratios to one another of any of the preceding. The HSD can include a metabolic factor, a health-related factor, or a demographic-related factor. The code can include code to cause the processor to execute the trained machine learning model to generate an indication of whether the diabetic human subject will experience a progressive decline in kidney function over a period of time. |
| FILED | Friday, February 12, 2021 |
| APPL NO | 17/797400 |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) G16B 40/20 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230080414 | Yazden-Shahmorad et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Azadeh Yazden-Shahmorad (Seattle, Washington); Julien Bloch (Seattle, Washington); Alexander Greaves-Tunnell (Seattle, Washington); Eric Shea-Brown (Seattle, Washington); Ali Shojaie (Seattle, Washington); Zaid Harchaoui (Seattle, Washington) |
| ABSTRACT | Cortical network structure that mediates response to brain stimulation, and associated systems and methods are disclosed herein. In one embodiment, a method for brain stimulation includes: delivering an input stimulus to an area of the brain, via a cortical implant; in response to delivering the input stimulus, generating neural signals in the brain; and generating a predicted outcome of the input stimulus. The predicted outcome is based on a set of data derived from a model that combines: protocol features that are brain agnostic, and network features that are based on interactions between neural nodes of the brain. |
| FILED | Thursday, September 01, 2022 |
| APPL NO | 17/901496 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0529 (20130101) Original (OR) Class A61N 1/36082 (20130101) A61N 1/36139 (20130101) A61N 5/067 (20210801) A61N 5/0601 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230080670 | Schwartz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jacob Schwartz (Tucson, Arizona); Matthew Rollins (Tucson, Arizona); Nasiha S. Ahmed (Tucson, Arizona) |
| ABSTRACT | Methods and compositions for inducing cell death in cells with FET-fused oncogenes, as well as methods for treating tumors with FET-fused oncogenes, such as cells and tumors associated with Ewing's sarcoma and fibromyxoid Iposarcoma. Oncogenes may include the EWS-FLI1 oncogene, FUS-FLI1 oncogene, FUS-CHOP oncogene, etc. The methods feature herein administering to a patient with a FET-fused oncogene tumor a combination of a DNA damaging agent and a transcription inhibitor. The combination of the transcription inhibitor and DNA damaging agent causes death of cells in the tumor. |
| FILED | Monday, April 06, 2020 |
| APPL NO | 17/600817 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/453 (20130101) A61K 31/502 (20130101) A61K 31/4184 (20130101) A61K 31/4745 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230080742 | Levin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Noam Levin (Rockville, Maryland); Rami Yoseph (Gaithersburg, Maryland); Biman Paria (Germantown, Maryland); Steven A. Rosenberg (Potomac, Maryland) |
| ABSTRACT | Disclosed is an isolated or purified T cell receptor (TCR), wherein the TCR has antigenic specificity for a mutated human RAS amino acid sequence with a substitution of glycine at position 12 with aspartic acid presented by a human leukocyte antigen (HLA) Class I molecule. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal. |
| FILED | Friday, February 12, 2021 |
| APPL NO | 17/799163 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 37/04 (20180101) Peptides C07K 14/7051 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230081105 | Tan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of South Carolina (Columbia, South Carolina) |
| ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
| INVENTOR(S) | Wenbin Tan (Columbia, South Carolina); Rong Yin (Columbia, South Carolina); Li Meng (Shanghai, China PRC) |
| ABSTRACT | Described herein are systems and methods for a type of paradigm-shift nanoparticles functionalized endothelial optical exosomes for vascular malformation treatment, including Port Wine Stain, using exosomes as a drug delivery vehicle in combination with Near-Infrared-mediated laser therapy. |
| FILED | Friday, July 15, 2022 |
| APPL NO | 17/865513 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/203 (20130101) A61B 2018/00452 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/5068 (20130101) A61K 41/0057 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230081146 | Gallo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard L. Gallo (San Diego, California); Tatsuya Dokoshi (La Jolla, California) |
| ABSTRACT | The disclosure relates to compositions and methods for treating infection, allergic reactions, colitis, IBD, contact dermatitis, psoriasis, atopic dermatitis, graft vs. host disease and disorders and other disease and disorders comprising dendritic cell activation as well as compositions and method to improve allergen sensitization. |
| FILED | Monday, September 12, 2022 |
| APPL NO | 17/931491 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/702 (20130101) A61K 31/713 (20130101) Original (OR) Class A61K 31/728 (20130101) A61K 38/47 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) C12N 9/2474 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230081264 | Bennett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Glia Biotherapeutics, Inc. (New York, New York); The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Frederick Christian Bennett (Philadelphia, Pennsylvania); Peter A. Thompson (New York, New York); Mariko L. Bennett (Philadelphia, Pennsylvania); Andy J. Jennings (San Diego, California) |
| ABSTRACT | The present disclosure provides methods and compositions for microglia replacement therapy in a subject in need thereof. In some cases, the method involves administering myeloid cells to the central nervous system of a subject. In some cases, the myeloid cells are derived from embryonic or extraembryonic tissue. In some cases, the myeloid cells are genetically modified. The genetic modification may include a colony stimulating factor 1 receptor (CSF1R) variant that is resistant to a CSF1R inhibitor, yet retains sensitivity to its ligand (e.g., CSF1, IL34). |
| FILED | Tuesday, September 10, 2019 |
| APPL NO | 16/566675 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/15 (20130101) Original (OR) Class A61K 45/06 (20130101) Peptides C07K 14/7153 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0622 (20130101) C12N 5/0642 (20130101) C12N 9/12 (20130101) C12N 2506/11 (20130101) Enzymes C12Y 207/10001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230081305 | Islam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nahid Ul Islam (Mesa, Arizona); Shiv Gehlot (Darwara, India); Zongwei Zhou (Tempe, Arizona); Jianming Liang (Scotsdale, Arizona) |
| ABSTRACT | Described herein are means for systematically determining an optimal approach for the computer-aided diagnosis of a pulmonary embolism, in the context of processing medical imaging. According to a particular embodiment, there is a system specially configured for diagnosing a Pulmonary Embolism (PE) within new medical images which form no part of the dataset upon which the AI model was trained. Such a system executes operations for receiving a plurality of medical images and processing the plurality of medical images by executing an image-level classification algorithm to determine the presence or absence of a Pulmonary Embolism (PE) within each image via operations including: pre-training an AI model through supervised learning to identify ground truth; fine-tuning the pre-trained AI model specifically for PE diagnosis to generate a pre-trained PE diagnosis and detection AI model; wherein the pre-trained AI model is based on a modified CNN architecture having introduced therein a squeeze and excitation (SE) block enabling the CNN architecture to extract informative features from the plurality of medical images by fusing spatial and channel-wise information; applying the pre-trained PE diagnosis and detection AI model to new medical images to render a prediction as to the presence or absence of the Pulmonary Embolism within the new medical images; and outputting the prediction as a PE diagnosis for a medical patient. |
| FILED | Wednesday, September 14, 2022 |
| APPL NO | 17/944881 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/50 (20130101) Image Data Processing or Generation, in General G06T 3/40 (20130101) G06T 7/0012 (20130101) Original (OR) Class G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30061 (20130101) G06T 2207/30101 (20130101) Image or Video Recognition or Understanding G06V 10/82 (20220101) G06V 10/774 (20220101) G06V 10/7715 (20220101) G06V 2201/03 (20220101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230081343 | Bacchetta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rosa Bacchetta (Menlo Park, California); Maria-Grazia Roncarolo (Menlo Park, California); Matthew Porteus (Stanford, California); Marianne Goodwin (Redwood City, California) |
| ABSTRACT | Compositions and methods are provided relating to FOXP3 gene edited hematopoietic cells, include hematopoietic stem and progenitor cells, lymphoid progenitor cells, and CD4+ T cells. The gene edited cells are useful in cellular therapy to restore normal immune functions and promote immune tolerance. In particular, CD4edFOXP3 T cells, which may be differentiated from FOXP3 gene edited hematopoietic progenitor cells, can physiologically express functional FOXP3 and exert normal immune responses as effector T cells or have immune suppressive characteristics as naturally occurring Treg cells. |
| FILED | Saturday, February 13, 2021 |
| APPL NO | 17/760264 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0637 (20130101) Original (OR) Class C12N 9/22 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230081539 | Fu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jie Fu (Baltimore, Maryland); Justin Hanes (Baltimore, Maryland); Peter Campochiaro (Baltimore, Maryland); Laura Ensign (Baltimore, Maryland) |
| ABSTRACT | A population of polymeric particles for controlled release of therapeutic agents which have unacceptable toxicity when administered intravitreally can be safely administered suprachoroidally at the same intravitreal concentration or dose. In a preferred embodiment, the particles have a high loading of the agent and is released without a substantial initial burst release. Examples demonstrate safety and efficacy of delivery of acriflavine-containing particles when administered suprachoroidally. The examples demonstrate sustained release with low to no burst release of the highly water soluble agent for up to 60 days. |
| FILED | Friday, February 19, 2021 |
| APPL NO | 17/800838 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/10 (20130101) A61K 9/0048 (20130101) A61K 31/704 (20130101) A61K 31/765 (20130101) Original (OR) Class A61K 31/7084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230081648 | Yan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Pingkun Yan (Clifton Park, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Pingkun Yan (Clifton Park, New York) |
| ABSTRACT | One embodiment provides an apparatus for registering a two dimensional (2D) ultrasound (US) frame and a three dimensional (3D) magnetic resonance (MR) volume. The apparatus includes a first deep neural network (DNN) and an image fusion management circuitry. The first DNN is configured to determine a 2D US pose vector based, at least in part, on 2D US frame data. The image fusion management circuitry is configured to register the 2D US frame data and a 3D MR volume data. The registering is based, at least in part, on the |
| FILED | Friday, January 15, 2021 |
| APPL NO | 17/793215 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/30 (20170101) Original (OR) Class G06T 7/70 (20170101) G06T 2200/04 (20130101) G06T 2207/10088 (20130101) G06T 2207/10132 (20130101) G06T 2207/20016 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/20221 (20130101) G06T 2207/30081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230081679 | DESHONG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Philip R. DESHONG (Silver Spring, Maryland); David WATTS (San Mateo, California); Daniel C. STEIN (Silver Spring, Maryland); Paul PAUKSTELIS (Silver Spring, Maryland); Emily LUTERAN (Adelphi, Maryland) |
| ABSTRACT | The present disclosure provides catanionic surfactant vesicles (SVs). The vesicles may be functionalized on their outer leaflet such that they may be biologically active. The vesicles may encapsulate (at least partially in the lumen and/or at least partially in the leaflet) one or more small molecules, one or more RNAs, one or more DNAs, and/or one or more proteins/peptides. Also provided are compositions comprising the vesicles (e.g., vaccine compositions comprising the vesicles) and methods of making and using the same. |
| FILED | Friday, September 02, 2022 |
| APPL NO | 17/929630 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1272 (20130101) Original (OR) Class A61K 9/1277 (20130101) A61K 39/39 (20130101) A61K 2039/55555 (20130101) Peptides C07K 16/2818 (20130101) C07K 16/2887 (20130101) C07K 16/3015 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1135 (20130101) C12N 15/1138 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230082180 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeong Nyeon Kim (Palo Alto, California); Kamyar Firouzi (San Jose, California); Martin Loynaz Prieto (Palo Alto, California); Merritt C. Maduke (Los Altos, California); Butrus T. Khuri-Yakub (Palo Alto, California) |
| ABSTRACT | Ultrasonic excitation to a sample is provided with an apparatus including: a cylindrical ultrasonic transducer, and a plate disposed on an end of the cylindrical ultrasonic transducer. The ultrasonic transducer is configured to provide a vertical vibration in operation. A Lamb wave vibration is generated in the plate by the vertical vibration of the ultrasonic transducer. The Lamb wave vibration converges at a central region of the plate, where a sample is disposed. Alternatively, a cylindrical array of ultrasonic transducers can be used instead of a single cylindrical transducer. Such an array can be driven as a phased array for beam shaping and/or multi-focusing. |
| FILED | Monday, September 12, 2022 |
| APPL NO | 17/942841 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) Original (OR) Class B01L 2300/0645 (20130101) B01L 2300/0832 (20130101) B01L 2400/0439 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/02 (20130101) G01N 29/043 (20130101) G01N 2291/106 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230082272 | EGAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TargaGenix, Inc. (Stony Brook, New York); The Research Foundation for the State University of New York (Albany, New York); Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | TargaGenix, Inc. (Stony Brook, New York); The Research Foundation for the State University of New York (Albany, New York); Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | James E. EGAN (Stony Brook, New York); Mansoor M. AMIJI (Attleboro, Massachusetts); Iwao OJIMA (Port Jefferson, New York) |
| ABSTRACT | A composition of an omega-3 polyunsaturated fatty acid (PUFA)-taxoid conjugate formulated in an oil-in-water nanoemulsion (NE) drug delivery system in combination with an immune-oncology (IO) agent to enhance therapeutic efficacy in refractory cancers, such as PDAC. A method of treating cancer, by administering an effective amount of a pharmaceutical composition including an omega03 PUFA-taxoid conjugate in combination with an IO agent encapsulated in an NE drug delivery system to a subject in need of treatment, and treating cancer. |
| FILED | Monday, November 14, 2022 |
| APPL NO | 17/986430 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) Original (OR) Class A61K 31/337 (20130101) A61K 39/39558 (20130101) A61K 47/44 (20130101) A61K 47/542 (20170801) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2827 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230082358 | Kimicata et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Megan Kimicata (New Market, Maryland); John Patrick Fisher (Kensington, Maryland) |
| ABSTRACT | Current approaches in small diameter vascular grafts for coronary artery bypass surgeries fail to address physiological variations along the graft that contribute to thrombus formation and ultimately graft failure. An interlayer drug delivery system can sustain delivery of heparin through the graft with a high degree of temporal and spatial control. A heparin-loaded gelatin methacrylate interlayer sits between a biohybrid composed of decellularized bovine pericardium and poly(propylene fumarate) and UV crosslinking is controlled via 3D printed shadow masks. The masks enable control of the resultant gelMA crosslinking and properties by modulating the incident light intensity on the graft. High doses of heparin have detrimental effects on endothelial cell function. When exposed to heparin in a slower, more sustained manner consistent with the masks, endothelial cells behave similarly to untreated cells. Slower release profiles cause significantly more release of tissue factor pathway inhibitor, an anticoagulant, than a faster release profile. |
| FILED | Thursday, September 08, 2022 |
| APPL NO | 17/930469 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/54 (20130101) Original (OR) Class A61L 27/507 (20130101) A61L 27/3625 (20130101) A61L 33/0011 (20130101) A61L 33/124 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230082744 | Smith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (EVANSTON, Illinois); BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (LINCOLN, Nebraska); TRUSTEES OF TIFTS COLLEGE (AKA TUFTS UNIVERSITY) (MEDFORD, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gregory A. Smith (Oak Park, Illinois); Patricia Jane Sollars (Lincoln, Nebraska); Gary Edward Pickard (Lincoln, Nebraska); Ekaterina E. Heldwein (Belmont, Massachusetts) |
| ABSTRACT | Provided herein are compositions and methods for vaccination and research applications. In particular, provided herein are non-neuroinvasive herpesviruses and alpha herpesviruses and uses thereof. |
| FILED | Thursday, September 15, 2022 |
| APPL NO | 17/932320 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/763 (20130101) A61K 39/12 (20130101) A61K 39/25 (20130101) A61K 39/245 (20130101) A61K 2039/5254 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230082787 | Levin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Noam Levin (Rockville, Maryland); Maria R. Parkhurst (Ellicott City, Maryland); Frank J. Lowery, III (Clarksburg, Maryland); Steven A. Rosenberg (Potomac, Maryland) |
| ABSTRACT | Disclosed are isolated or purified T cell receptors (TCRs), wherein the TCRs have antigenic specificity for a mutated RAS amino acid sequence presented by a human leukocyte antigen (HLA) Class I molecule. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal |
| FILED | Friday, February 12, 2021 |
| APPL NO | 17/799193 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) A61P 35/00 (20180101) A61P 37/04 (20180101) Peptides C07K 14/7051 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230082873 | Lockery |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NemaMetrix, Inc (Eugene, Oregon); University of Oregon (Eugene, Oregon) |
| ASSIGNEE(S) | NemaMetrix, Inc (Eugene, Oregon); University of Oregon (Eugene, Oregon) |
| INVENTOR(S) | Shawn Lockery (Eugene, Oregon) |
| ABSTRACT | The present disclosure provides a microfluidic device and system for measuring a composite electropharyngeogram (EPG) signal from a pool of multiple nematodes, wherein the composite EPG signal is measured from the pool of nematodes present in a single recording channel connected to two or more integrated electrodes. The microfluidic device includes an inlet port and outlet port directly connected to a single recording channel and two or more electrodes directly connected to the recording channel. The recording channel is configured to hold 10 to 10,000 nematodes. |
| FILED | Monday, September 19, 2022 |
| APPL NO | 17/947846 |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 29/005 (20130101) A01K 67/0336 (20130101) A01K 2227/703 (20130101) A01K 2267/0393 (20130101) Diagnosis; Surgery; Identification A61B 5/0004 (20130101) Veterinary Instruments, Implements, Tools, or Methods A61D 3/00 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/02 (20130101) G01N 33/5085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230082929 | Zhao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Wistar Institute of Anatomy and Biology (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bo Zhao (Philadelphia, Pennsylvania); Rugang Zhang (Elkins Park, Pennsylvania) |
| ABSTRACT | Compositions and methods for treating cancer in a subject in need thereof is provided. In certain embodiments, the method includes administering therapy-induced senescent (TIS) cells and an immune checkpoint inhibitor to the subject. Also provided are compositions comprising therapy-induced senescent (TIS) cells. |
| FILED | Friday, February 12, 2021 |
| APPL NO | 17/760463 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/13 (20130101) Original (OR) Class A61K 39/39558 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 15/00 (20180101) A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0693 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230083273 | Zhao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhongchao Zhao (Bloomington, Indiana); Adam Zlotnick (Bloomington, Indiana) |
| ABSTRACT | Embodiments described herein provide orthohepadnavirus capsid protein (Cp) heterodimers, bicistronic vectors encoding the heterodimers, and methods for producing the heterodimers. The heterodimers can be used to form mosaic virus-like particles. In certain embodiments, the heterodimers can form a hexamer, which in turn can be used to nucleate capsid formation, resulting in a Janus particle-like virus-like particle. The hexamer's can then be removed, leaving holey capsids. The capsids can be loaded with, for example, one or more polypeptides, small molecules, or a combination of polypeptides and small molecules. The holes of the holey capsids can be filled with another orthohepadnavirus heterodimer or a homodimer. |
| FILED | Friday, February 12, 2021 |
| APPL NO | 17/799629 |
| CURRENT CPC | Peptides C07K 14/02 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) C12N 2730/10122 (20130101) C12N 2730/10123 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230083388 | Spiegel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Spiegel (New Haven, Connecticut); David Caianiello (Brooklyn, New York); Mengwen Zhang (New Haven, Connecticut) |
| ABSTRACT | The present disclosure is directed to bifunctional small molecules which contain a circulating protein binding moiety (CPBM) linked through a linker group to a cellular receptor binding moiety (CRBM) which is a membrane receptor of degrading cell such as a hepatocyte or other degrading cell. In certain embodiments, the (CRBM) is a moiety which binds to asialoglycoprotein receptor (an asialoglycoprotein receptor binding moiety, or ASGPRBM) of a hepatocyte. In additional embodiments, the (CRBM) is a moiety which binds to a receptor of other cells which can degrade proteins, such as a LRP1, LDLR, FcγRI, FcRN, Transferrin or Macrophage Scavenger receptor. |
| FILED | Tuesday, March 15, 2022 |
| APPL NO | 17/695645 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/54 (20170801) A61K 47/55 (20170801) A61K 47/64 (20170801) A61K 47/545 (20170801) Original (OR) Class A61K 47/549 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230083394 | DELISA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew P. DELISA (Ithaca, New York); Kevin WEYANT (Ithaca, New York) |
| ABSTRACT | The present disclosure is directed to a system for displaying antigens. This system includes an outer membrane vesicle comprising a lipid bilayer and a synthetic antigen receptor comprising an outer membrane scaffold protein fused to a biotin-binding protein, where the outer membrane scaffold protein is incorporated in the lipid bilayer and the biotin-binding protein is displayed outside the outer membrane vesicle. Also disclosed are therapeutic compositions, nucleic acid constructs, expression vectors, and methods of eliciting an immune response in a subject. |
| FILED | Thursday, August 25, 2022 |
| APPL NO | 17/895245 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/385 (20130101) A61K 47/61 (20170801) A61K 47/543 (20170801) A61K 47/557 (20170801) Peptides C07K 14/005 (20130101) C07K 14/195 (20130101) C07K 16/44 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1037 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230083661 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Kansas (Lawrence, Kansas); The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xinmai Yang (Lawrence, Kansas); Xueding Wang (Ann Arbor, Michigan); Yannis M. Paulus (Ann Arbor, Michigan) |
| ABSTRACT | A method of removing microvessels includes applying a burst of acoustic energy at a target location, applying a pulse of optical energy at the target location, and promoting cavitation at the target location by synchronizing an arrival of the burst of acoustic energy and the optical energy at the target location. The burst of acoustic energy has a pressure below 5.0 MPa. The pulse of optical energy at the target location has a fluence less than 100 mJ/cm2. At least a portion of the pulse is concurrent with the burst and the optical energy has an optical area that is overlapping with an acoustic area of the acoustic energy at the target location. |
| FILED | Friday, November 18, 2022 |
| APPL NO | 17/990454 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1079 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/008 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/022 (20130101) Original (OR) Class A61N 2007/0095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230083866 | NADKARNI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Seemantini NADKARNI (Boston, Massachusetts); Zeinab HAJJARIAN-KASHANY (Boston, Massachusetts) |
| ABSTRACT | A method for non-destructively estimating an average size of scattering particles in a sample, including: transmitting, using a coherent light source, polarized light to the sample; obtaining, using a detector, polarized light reflected from the sample, the polarized light comprising a parallel polarized component and a perpendicular polarized component; determining, using a processor, speckle decorrelation rates for the parallel polarized component and the perpendicular polarized component; and estimating, using the processor, the average size of scattering particles in the sample based on the speckle decorrelation rates for the parallel polarized component and the perpendicular polarized component. |
| FILED | Monday, February 01, 2021 |
| APPL NO | 17/759738 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/0211 (20130101) Original (OR) Class G01N 2015/0065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230084160 | Han et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AT and T Intellectual Property I, L.P. (Atlanta, Georgia); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bo Han (Bridgewater, New Jersey); Vijay Gopalakrishnan (Edison, New Jersey); Muhammad Bilal Anwer (Branchburg, New Jersey); Zhi-Li Zhang (Eden Prairie, Minnesota); Yang Zhang (Saint Paul, Minnesota) |
| ABSTRACT | Systems and methods are disclosed for parallelizing service function chains. A method comprises receiving a sequential service function chain comprising a plurality of network functions, receiving a plurality of operations, determining at least two network functions are capable of being parallelized, aggregating operations of the plurality of operations associated with the at least two network functions into a network function segment, determining whether another network function is capable of being parallelized with the network function segment, based on the determining: aggregating an operation associated with the another network function into the network function segment when the another network function is capable of being parallelized with the network function segment, or pushing the network function segment as a completed segment of a hybrid service function chain when the another network function is not capable of being parallelized with the network function segment, and implementing the hybrid service function chain. |
| FILED | Monday, November 14, 2022 |
| APPL NO | 18/055233 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/5077 (20130101) G06F 9/45558 (20130101) G06F 2009/45595 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 41/0893 (20130101) Original (OR) Class H04L 45/64 (20130101) H04L 61/256 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230084515 | Audoly et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee); Duet BioSystems, Inc. (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Laurent Audoly (Brookline, Massachusetts); Buddhi Bishal Paudel (Nashville, Tennessee); Vito Quaranta (Nashville, Tennessee) |
| ABSTRACT | The invention provides methods, compositions, and medical kits for treating cancer using combination therapy including a BRAF and/or MEK inhibitor and at least one additional therapeutic agent that inhibits at least one target impacting oxidation state of the cancer. |
| FILED | Friday, February 19, 2021 |
| APPL NO | 17/800394 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/11 (20130101) A61K 31/33 (20130101) A61K 31/198 (20130101) A61K 31/352 (20130101) A61K 31/437 (20130101) Original (OR) Class A61K 31/506 (20130101) A61K 31/517 (20130101) A61K 31/519 (20130101) A61K 31/635 (20130101) A61K 31/4184 (20130101) A61K 31/4439 (20130101) A61K 31/4523 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230084773 | Shain |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Alain Hunter Shain (San Francisco, California) |
| ABSTRACT | Methods for detecting somatic mutations in single cells are described. Specifically, the disclosure provides methods of identifying somatic mutations in individual cells, comprising: providing a compartment containing only one somatic cell; generating genomic DNA and mRNA sequencing reads from the somatic cell; identifying potential mutations from the genomic DNA and mRNA sequencing reads relative to a control sequence; discarding artifact differences in the sequencing reads, thereby identifying somatic mutations in the individual cells compared to a control sequence. |
| FILED | Wednesday, February 24, 2021 |
| APPL NO | 17/802084 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) C12Q 1/6886 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230085214 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| INVENTOR(S) | Hua Wang (Cambridge, Massachusetts); Andrew Salim Khalil (Cambridge, Massachusetts); David J. Mooney (Sudbury, Massachusetts); Rudolf Jaenisch (Cambridge, Massachusetts) |
| ABSTRACT | Disclosed herein are compositions and methods for labeling cells using click chemistry reagents. The compositions and methods disclosed herein provide a specific and efficient means of localizing desired agents to a variety of cell types in vivo and in vitro. The compositions and methods disclosed herein can be used to deliver a variety of desired agents to a cell or population of cells to direct cell fate and/or cell differentiation. |
| FILED | Wednesday, July 20, 2022 |
| APPL NO | 17/869611 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/549 (20170801) A61K 47/555 (20170801) Original (OR) Class Peptides C07K 2319/60 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) C12N 2310/3517 (20130101) C12N 2320/32 (20130101) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230085308 | QUIJANO et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Elias QUIJANO (Durham, Connecticut); Peter GLAZER (Guilford, Connecticut) |
| ABSTRACT | Compositions and methods of use thereof for delivering nucleic acid cargo into cells are provided. The compositions typically include (a) a 3E10 monoclonal antibody or an antigen binding, cell-penetrating fragment thereof; a monovalent, divalent, or multivalent single chain variable fragment (scFv); or a diabody; or humanized form or variant thereof, and (b) a nucleic acid cargo including, for example, a nucleic acid encoding a polypeptide, a functional nucleic acid, a nucleic acid encoding a functional nucleic acid, or a combination thereof. Elements (a) and (b) are typically non-covalently linked to form a complex. |
| FILED | Tuesday, August 30, 2022 |
| APPL NO | 17/823488 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) Original (OR) Class Peptides C07K 16/44 (20130101) C07K 2317/77 (20130101) C07K 2317/565 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) C12N 15/111 (20130101) C12N 2310/14 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230085439 | Mousa et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| INVENTOR(S) | Jarrod Mousa (Athens, Georgia); Ralph A. Tripp (Watkinsville, Georgia); Jiachen Huang (Athens, Georgia) |
| ABSTRACT | Antibodies and antigen binding fragments that specifically bind to human metapneumovirus (hMPV) F protein and neutralize hMPV are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. The disclosed antibodies, antigen binding fragments, nucleic acids and vectors can be used, for example, to inhibit an hMPV infection or detect a hMPV infection. |
| FILED | Tuesday, May 21, 2019 |
| APPL NO | 17/612954 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/31 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0686 (20130101) C12N 15/62 (20130101) C12N 15/85 (20130101) C12N 2510/02 (20130101) C12N 2800/107 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230085485 | Williams et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CITY OF HOPE (Duarte, California); THOMAS JEFFERSON UNIVERSITY (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John C. Williams (Monrovia, California); Cindy Zer (Duarte, California); Kendra N. Avery (Pasadena, California); Ulrich Rodeck (Philadelphia, Pennsylvania); Joshua M. Donaldson (Lumberion, New Jersey); Csaba Kari (Rosemont, California) |
| ABSTRACT | In one embodiment, a masked monoclonal antibody (mAb) is provided, the mAb, encoded by a nucleic acid sequence or an amino acid sequence molecule comprising a signal sequence, a masking epitope sequence, a linker sequence that is cleavable by a protease specific to a target tissue; and an antibody or a functional fragment thereof. In another embodiment, a masked monoclonal antibody (mAb) is provided, which includes a therapeutic mAb and a mask, the mask comprising protein A and protein L attached by a protease cleavable linker. |
| FILED | Monday, April 25, 2022 |
| APPL NO | 17/660603 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/55 (20170801) Original (OR) Class Peptides C07K 16/30 (20130101) C07K 16/2863 (20130101) C07K 2317/31 (20130101) C07K 2317/33 (20130101) C07K 2317/34 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/622 (20130101) C07K 2319/32 (20130101) C07K 2319/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230085492 | Khademhosseini et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alireza Khademhosseini (Cambridge, Massachusetts); Rahmi Oklu (Scottsdale, Arizona) |
| ABSTRACT | This disclosure relates to methods of using shear-thinning compositions in the treatment of a vascular disorders, cancers, infections, abscesses, and fistulas. |
| FILED | Tuesday, July 12, 2022 |
| APPL NO | 17/862959 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0019 (20130101) A61K 38/39 (20130101) Original (OR) Class A61K 47/02 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230085578 | GEORGE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The George Washington University (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sharon Ann GEORGE (Washington, District of Columbia); Igor R. EFIMOV (Washington, District of Columbia) |
| ABSTRACT | Systems and methods are disclosed for an optical mapping device. The device emits different wavelengths of light from a plurality of light sources to a cardiac tissue and passes the light through a lens, a first filter cube in the path of the light with a first light filter, a second light filter, and a third light filter. Light passing through the filters is recorded by three cameras that each record an indicator of cardiac physiology, which are mapped simultaneously by the device. |
| FILED | Friday, September 02, 2022 |
| APPL NO | 17/901979 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0066 (20130101) Original (OR) Class A61B 5/0077 (20130101) A61B 2018/00351 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20230077902 | Tse et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen D. Tse (New Brunswick, New Jersey); Chuiyuan Meng (New Brunswick, New Jersey); Thomas Nosker (New Brunswick, New Jersey); Bernard H. Kear (New Brunswick, New Jersey); Mustafa M. Mozael (New Brunswick, New Jersey) |
| ABSTRACT | Described herein is a submerged-plasma process for the production of amorphous and nanocrystalline nanostructured materials, depending on processing conditions, from precursors that can be in the liquid or injected into the plasma or both. |
| FILED | Wednesday, September 14, 2022 |
| APPL NO | 17/932044 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/325 (20130101) Original (OR) Class C23C 14/0605 (20130101) C23C 14/0623 (20130101) C23C 14/0647 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230077940 | Xu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Ting Xu (Berkeley, California); Christopher A. DelRe (Berkeley, California) |
| ABSTRACT | Compositions comprise synergistic enzyme mixtures, and related methods, to realize near-complete depolymerization in biodegradable polymer/additive blends. |
| FILED | Friday, September 09, 2022 |
| APPL NO | 17/941026 |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 11/105 (20130101) Original (OR) Class C08J 2367/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230078543 | Wood et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nathaniel Joseph Wood (Columbus, Ohio); David John Hoelzle (Columbus, Ohio) |
| ABSTRACT | Estimation algorithms, methods, and systems are provided that estimate the internal temperatures inside of a part being built using a Finite Element Method (FEM)-based thermal model of Powder Bed Fusion (PBF) heat transfer. Closed-loop state estimation is applied to the problem of monitoring temperature fields within parts during the PBF build process. The PBF laser is very small, therefore, so too are the FEM elements nearby the laser. Thus, as the PBF laser moves, a region of high mesh density moves along with it as it progresses over a geometry. In an aspect, regions of high mesh density are predetermined for each time step according to a predefined schedule of laser movements. |
| FILED | Thursday, November 10, 2022 |
| APPL NO | 18/054535 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/28 (20210101) B22F 10/80 (20210101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 40/00 (20141201) B33Y 50/00 (20141201) Electric Digital Data Processing G06F 30/23 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230078644 | Alcorn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Definitive Biotechnologies LLC (Elkridge, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Timothy Alcorn (Raleigh, North Carolina); Robert Altavela (Webster, New York); Michael Carlotta (Lilburn, Georgia); David Cigna (Rochester, New York); John C. Detter (Melbourne Beach, Florida); Steven Dietl (Ontario, New York); Charles Facchini (Webster, New York); Todd Haran (Bloomfield, New York); Roger Markham (Webster, New York); Michael Murray (Bloomfield, New York); Scott Rosebrough (Avon, New York); Jeffrey Serbicki (Holley, New York); Qing Yang (Pittsford, New York) |
| ABSTRACT | A device for detecting nucleic acids in a biological sample has a sample port, a lysis station and a sample conduit configured to mix a sample and lysis agent to form a sample-lysis mixture, pass the sample-lysis mixture across a solid-state membrane to capture nucleic acids in the biological sample therein, and receive the remainder of the sample-lysis mixture in a waste chamber. The wash station is configured to introduce the wash solution following the sample-lysis mixture, pass the wash solution across the solid-state membrane to purify nucleic acids captured therein, and receive the wash solution from the solid-state membrane in the waste chamber. The elution station is configured to pass the eluent across the solid-state membrane, elute captured nucleic acids from the solid-state membrane, and pass the captured nucleic acids into one or more reaction chambers for amplifying and detecting the captured nucleic acids. |
| FILED | Friday, September 09, 2022 |
| APPL NO | 17/941816 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5029 (20130101) B01L 3/502715 (20130101) B01L 3/502723 (20130101) B01L 3/502738 (20130101) B01L 3/502753 (20130101) Original (OR) Class B01L 7/52 (20130101) B01L 2200/04 (20130101) B01L 2200/10 (20130101) B01L 2200/085 (20130101) B01L 2200/0652 (20130101) B01L 2200/0684 (20130101) B01L 2200/0689 (20130101) B01L 2300/06 (20130101) B01L 2300/044 (20130101) B01L 2300/165 (20130101) B01L 2300/168 (20130101) B01L 2400/0487 (20130101) B01L 2400/0694 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230079117 | BEEBY et al. |
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| FUNDED BY |
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| APPLICANT(S) | Certus Critical Care, Inc. (Salt Lake City, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ruth BEEBY (Santa Clara, California); Patrick Ryan KOLBAY (Salt Lake City, Utah); David POISNER (Carmichael, California); Daniel FONG (Sacramento, California) |
| ABSTRACT | Devices, systems, and methods for minimization of backlash in a syringe pump are described herein. Syringe pumps may comprise a syringe including a cylindrical body and a plunger, and a controller. The plunger may comprise a linear gear that may operably couple with a circular gear in the controller. The controller may be configured to bias the circular gear in a biasing rotational direction, thereby positioning the plunger to move towards a biasing translational direction. The methods may comprise determining a backlash compensation amount, determining a fluid transfer movement amount, moving at least one component of the syringe pump the backlash compensation amount and the fluid transfer movement amount in a first direction, and moving the at least one component of the syringe pump a biasing movement amount in a second direction opposite the first direction to re-engage the first gear and the second gear to minimize backlash. |
| FILED | Thursday, June 16, 2022 |
| APPL NO | 17/842729 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/12109 (20130101) A61B 17/12136 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/14546 (20130101) A61M 25/10182 (20131105) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230079967 | Regeimbal et al. |
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| FUNDED BY |
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| APPLICANT(S) | United States of America as Represented by the Secretary of the Navy (Silver Spring, Maryland) |
| ASSIGNEE(S) | United States of America as Represented by the Secretary of the Navy (Silver Spring, Maryland) |
| INVENTOR(S) | James M. Regeimbal (Washington's Crossing, Pennsylvania); Biswajit Biswas (Germantown, Maryland); Matthew S. Henry (Thurmont, Maryland) |
| ABSTRACT | The subject matter of the instant invention relates to methods of compounding compositions comprising bacteriophage effective for treating bacterial infections, including but not limited to, multidrug resistant bacterial infections. The invention also relates to compositions, bacterial diversity sets, and phage libraries prepared according to the methods of the instant invention. |
| FILED | Tuesday, August 16, 2022 |
| APPL NO | 17/820035 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 30/04 (20130101) C40B 40/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230080146 | MONROE et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher MONROE (Ellicott City, Maryland); Marko CETINA (College Park, Maryland); Norbert LINKE (Stevenson, Maryland); Shantanu DEBNATH (College Park, Maryland) |
| ABSTRACT | The disclosure describes various aspects of optical control of atomic quantum bits (qubits) for phase control operations. More specifically, the disclosure describes methods for coherently controlling quantum phases on atomic qubits mediated by optical control fields, applying to quantum logic gates, and generalized interactions between qubits. Various attributes and settings of optical/qubit interactions (e.g., atomic energy structure, laser beam geometry, polarization, spectrum, phase, background magnetic field) are identified for imprinting and storing phase in qubits. The disclosure further describes how these control attributes are best matched in order to control and stabilize qubit interactions and allow extended phase-stable quantum gate sequences. |
| FILED | Thursday, May 06, 2021 |
| APPL NO | 17/313450 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Optical Computing Devices; G06E 1/00 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230080523 | DHINOJWALA et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ali DHINOJWALA (Akron, Ohio); Ming XIAO (Cambridge, Massachusetts); Ziying HU (Wilmette, Illinois); Matthew SHAWKEY (Ghent, Belgium); Nathan GIANNESCHI (Wilmette, Illinois) |
| ASSIGNEE(S) | THE UNIVERSITY OF AKRON (Akron, Ohio) |
| INVENTOR(S) | Ali DHINOJWALA (Akron, Ohio); Ming XIAO (Cambridge, Massachusetts); Ziying HU (Wilmette, Illinois); Matthew SHAWKEY (Ghent, Belgium); Nathan GIANNESCHI (Wilmette, Illinois) |
| ABSTRACT | In various embodiments, the present invention is directed to a facile one-pot reverse emulsion process to assemble core-shell nanoparticles (CS-SMNPs) into bright and noniridescent photonic supraballs. In one or more embodiments, the present invention is directed to core-shell nanoparticles having an inner high refractive index (RI) core and an outer low RI shell. In one or more embodiment, the present invention includes core-shell nanoparticles using high RI (˜1.74) melanin cores and low-RI (˜1.45) silica shells. In various embodiments, these nanoparticles may be self-assembled into bright and noniridescent supraballs using a scalable one-pot reverse emulsion process. According to various embodiments of the present invention, it is possible to generate a full spectrum of structural colors with the combination of only two ingredients, synthetic melanin and silica. |
| FILED | Tuesday, September 13, 2022 |
| APPL NO | 17/943667 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/18 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 67/0005 (20130101) C09B 67/0007 (20130101) C09B 69/104 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230081105 | Tan et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of South Carolina (Columbia, South Carolina) |
| ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
| INVENTOR(S) | Wenbin Tan (Columbia, South Carolina); Rong Yin (Columbia, South Carolina); Li Meng (Shanghai, China PRC) |
| ABSTRACT | Described herein are systems and methods for a type of paradigm-shift nanoparticles functionalized endothelial optical exosomes for vascular malformation treatment, including Port Wine Stain, using exosomes as a drug delivery vehicle in combination with Near-Infrared-mediated laser therapy. |
| FILED | Friday, July 15, 2022 |
| APPL NO | 17/865513 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/203 (20130101) A61B 2018/00452 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/5068 (20130101) A61K 41/0057 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230081282 | Sulc et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Petr Sulc (Scottsdale, Arkansas); Flavio Romano (Venezia, Italy); John Russo (Rome, Italy); Lukas Kroc (Praha, Czech Republic) |
| ABSTRACT | A general framework which transforms the inverse problem of self-assembly of colloidal crystals into a Boolean satisfiability problem for which solutions can be found numerically is described herein. Given a reference structure and the desired number of components, our approach produces designs for which the target structure is an energy minimum, and also allows to exclude solutions that correspond to competing structures. |
| FILED | Thursday, March 04, 2021 |
| APPL NO | 17/192305 |
| CURRENT CPC | Electric Digital Data Processing G06F 30/10 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230081408 | Petropulu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Athina Petropulu (Piscataway, New Jersey); SPILIOS EVMORFOS (Highland Park, New Jersey) |
| ABSTRACT | Various embodiments comprise systems, methods, architectures, mechanisms or apparatus for determining a subsequent time slot position for each of a plurality of spatially distributed relays configured for time slot based beamforming supporting a communication channel between a source and a destination. |
| FILED | Monday, August 15, 2022 |
| APPL NO | 17/888411 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/0454 (20130101) G06N 3/0481 (20130101) Transmission H04B 7/0617 (20130101) Original (OR) Class H04B 17/336 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230081451 | SALIM et al. |
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| FUNDED BY |
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| APPLICANT(S) | ColdQuanta, Inc. (Boulder, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Evan SALIM (Lafayette, Colorado); Dana Zachary ANDERSON (Boulder, Colorado); Jayson DENNEY (Golden, Colorado); Farhad MAJDETEIMOURI (Broomfield, Colorado) |
| ABSTRACT | A microwave sensor determines an electric-field strength of a microwave field populated by quantum particles in an ultra-high vacuum (UHV) cell. A probe laser beam and a coupling laser beam are directed into the UHV cell so that they are generally orthogonal to each other and intersect to define a “Rydberg” intersection, so-called as the quantum particles within the Rydberg intersection transition to a pair of Rydberg states. The frequency of the probe laser beam is swept so that a frequency spectrum of the probe laser beam can be captured. The frequency spectrum is analyzed to determine a frequency difference between Autler-Townes peaks. The electric-field strength of the microwave field within the Rydberg intersection is then determined based on this frequency difference. |
| FILED | Monday, May 02, 2022 |
| APPL NO | 17/734706 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 29/0885 (20130101) Original (OR) Class G01R 33/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230081593 | Caulfield et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cyan Systems (Santa Barbara, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John Caulfield (Santa Barbara, California); Jon Paul Curzan (Arroyo Grande, California) |
| ABSTRACT | A method that can detect targets is described. The method includes setting an integration time for each of a plurality of readout circuits based on a speed of the target. The readout circuits are configured to read pixels in an image detector. The pixels have a pitch of less than ten micrometers. The integration time is not more than five hundred microseconds and corresponds to a subframe of a fast frame image. The method also includes performing integrations of each readout circuit based on the integration time. Thus, a plurality of subframes are provided. A number of the subframes are averaged to provide the fast frame image. |
| FILED | Thursday, June 25, 2020 |
| APPL NO | 16/912606 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/248 (20170101) G06T 2207/10048 (20130101) G06T 2207/20212 (20130101) Pictorial Communication, e.g Television H04N 5/33 (20130101) H04N 5/353 (20130101) Original (OR) Class H04N 5/378 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230081641 | Nagano et al. |
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| FUNDED BY |
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| APPLICANT(S) | NVIDIA Corporation (Santa Clara, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Koki Nagano (Playa Vista, California); Eric Ryan Chan (Alameda, California); Sameh Khamis (Alameda, California); Shalini De Mello (San Francisco, California); Tero Tapani Karras (Helsinki, Finland); Orazio Gallo (Santa Cruz, California); Jonathan Tremblay (Redmond, Washington) |
| ABSTRACT | A single two-dimensional (2D) image can be used as input to obtain a three-dimensional (3D) representation of the 2D image. This is done by extracting features from the 2D image by an encoder and determining a 3D representation of the 2D image utilizing a trained 2D convolutional neural network (CNN). Volumetric rendering is then run on the 3D representation to combine features within one or more viewing directions, and the combined features are provided as input to a multilayer perceptron (MLP) that predicts and outputs color (or multi-dimensional neural features) and density values for each point within the 3D representation. As a result, single-image inverse rendering may be performed using only a single 2D image as input to create a corresponding 3D representation of the scene in the single 2D image. |
| FILED | Tuesday, December 14, 2021 |
| APPL NO | 17/551046 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) Image Data Processing or Generation, in General G06T 15/08 (20130101) Original (OR) Class G06T 17/005 (20130101) G06T 17/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230081695 | KOLODZIEJ et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kenneth E. KOLODZIEJ (Lexington, Massachusetts); Aidan U. COOKSON (Rowley, Massachusetts); Bradley Thomas PERRY (Nashua, New Hampshire) |
| ABSTRACT | A network device includes a transceiver configured to concurrently transmit signals and receive signals within a single frequency band resulting in radio-frequency signal interference. The device includes an analog canceler configured to mitigate the signal interference. The device includes a neural network that receives data that describes characteristics of the signal interference and provides coefficients for the analog canceler as outputs. The neural network-generated coefficients are applied to the analog canceler which uses them to cancel the signal interference. |
| FILED | Wednesday, December 02, 2020 |
| APPL NO | 17/109634 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) Transmission H04B 17/345 (20150115) Transmission of Digital Information, e.g Telegraphic Communication H04L 5/1461 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230081736 | Thayumanavan et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sankaran Thayumanavan (Amherst, Massachusetts); Kingshuk Dutta (Amherst, Massachusetts) |
| ABSTRACT | The invention provides novel polymers, crosslinked polymer-nucleic acid complexes, lipid-polymer-nucleic acid-based complexation and nanoassemblies, and nanoassembly-based intracellular delivery of nucleic acids and controlled release thereof upon degradation of the nanoassemblies in response to specific microenvironment in the cell, and compositions and methods of preparation and use thereof. |
| FILED | Monday, August 22, 2022 |
| APPL NO | 17/892637 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/58 (20170801) A61K 47/543 (20170801) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/385 (20200201) C08F 299/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230081740 | Prestigiacomo et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Joseph C. Prestigiacomo (Springfield, Virginia); Raymond C.Y. Auyeung (Alexandria, Virginia); Michael S. Osofsky (Clarksville, Maryland) |
| ABSTRACT | This disclosure teaches methods for making high-temperature superconducting striated tape combinations and the product high-temperature superconducting striated tape combinations. This disclosure describes an efficient and scalable method for aligning and bonding two superimposed high-temperature superconducting (HTS) filamentary tapes to form a single integrated tape structure. This invention aligns a bottom and top HTS tape with a thin intervening insulator layer with microscopic precision, and electrically connects the two sets of tape filaments with each other. The insulating layer also reinforces adhesion of the top and bottom tapes, mitigating mechanical stress at the electrical connections. The ability of this method to precisely align separate tapes to form a single tape structure makes it compatible with a reel-to-reel production process. |
| FILED | Thursday, October 27, 2022 |
| APPL NO | 17/975465 |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 1/0016 (20130101) B23K 3/0623 (20130101) B23K 35/0222 (20130101) B23K 2101/42 (20180801) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/681 (20130101) H01L 21/6836 (20130101) H01L 21/6838 (20130101) H01L 21/67092 (20130101) H01L 24/03 (20130101) H01L 39/24 (20130101) H01L 39/143 (20130101) Original (OR) Class H01L 39/248 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230081886 | Walsworth et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); The President and Fellows of Harvard College (Cambridge, Massachusetts); North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ronald Walsworth (Newton, Massachusetts); Nithya Arunkumar (Waltham, Massachusetts); Dominik Bucher (Puchheim, Germany); Matthew Turner (Cambridge, Massachusetts); David Glenn (Cambridge, Massachusetts); Matthew S. Rosen (Somerville, Massachusetts); Thomas Theis (Durham, North Carolina) |
| ABSTRACT | Systems and methods of quantum sensing include depositing a sample volume onto an ensemble of quantum defects, hyperpolarizing spins in the sample volume, performing a sensing sequence, and reading out information regarding electronic spin states of the quantum defects in the ensemble of quantum defects, which sense the hyperpolarized spins in the sample volume. |
| FILED | Wednesday, June 01, 2022 |
| APPL NO | 17/829565 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 24/08 (20130101) Original (OR) Class G01N 33/381 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230082712 | Pawelczyk et al. |
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| FUNDED BY |
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| APPLICANT(S) | Dragonfly Pictures, Inc. (Essington, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph Pawelczyk (Philadelphia, Pennsylvania); Kris Auker (Springfield, Pennsylvania); Trevor Stephens (Brookhaven, Pennsylvania); Jeff Field (Springfield, Pennsylvania); James Megariotis (Delran, New Jersey) |
| ABSTRACT | A method of aligning an aircraft with a landing platform in motion comprises measuring a GPS heading with at least one GPS sensor positioned at a known location relative to the landing platform while the landing platform is in motion, measuring an orientation of the aircraft with an orientation sensor fixed relative to the aircraft, calculating an orientation of the landing platform from the GPS heading, calculating an orientation offset between the measured orientation of the aircraft and the calculated orientation of the landing platform, and changing an orientation of the aircraft or the landing platform to reduce the orientation offset. A system for landing and securing an aircraft in an enclosure, a system for disconnecting a tether from an aircraft, and a system for landing an aircraft in an enclosure are also described. |
| FILED | Wednesday, May 25, 2022 |
| APPL NO | 17/824190 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 1/061 (20130101) B64C 39/022 (20130101) B64C 39/024 (20130101) B64C 2201/18 (20130101) B64C 2201/20 (20130101) B64C 2201/145 (20130101) B64C 2201/148 (20130101) Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 1/222 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230083257 | Pillai et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Texas A and M University System (College Station, Texas); Chevron U.S.A. Inc. (Richmond, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Suresh D. Pillai (College Station, Texas); David Staack (College Station, Texas); John Lassalle (College Station, Texas); Thomas Hoelen (Berkeley, California); Paul Bireta (Houston, Texas) |
| ABSTRACT | A method of waste treatment includes treating partially-dewatered matrix with a first electron-beam radiation dose. The treated partially-dewatered matrix is transferred to a digester where the treated partially-dewatered matrix is subjected to anaerobic digestion. Biogas is recovered from the treated partially-dewatered matrix during the anaerobic digestion. The treated partially-dewatered matrix is dried and subjected to a second electron-beam radiation dose. |
| FILED | Thursday, December 31, 2020 |
| APPL NO | 17/790336 |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 9/00 (20130101) Original (OR) Class C02F 2101/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230083388 | Spiegel et al. |
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| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Spiegel (New Haven, Connecticut); David Caianiello (Brooklyn, New York); Mengwen Zhang (New Haven, Connecticut) |
| ABSTRACT | The present disclosure is directed to bifunctional small molecules which contain a circulating protein binding moiety (CPBM) linked through a linker group to a cellular receptor binding moiety (CRBM) which is a membrane receptor of degrading cell such as a hepatocyte or other degrading cell. In certain embodiments, the (CRBM) is a moiety which binds to asialoglycoprotein receptor (an asialoglycoprotein receptor binding moiety, or ASGPRBM) of a hepatocyte. In additional embodiments, the (CRBM) is a moiety which binds to a receptor of other cells which can degrade proteins, such as a LRP1, LDLR, FcγRI, FcRN, Transferrin or Macrophage Scavenger receptor. |
| FILED | Tuesday, March 15, 2022 |
| APPL NO | 17/695645 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/54 (20170801) A61K 47/55 (20170801) A61K 47/64 (20170801) A61K 47/545 (20170801) Original (OR) Class A61K 47/549 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230083394 | DELISA et al. |
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| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew P. DELISA (Ithaca, New York); Kevin WEYANT (Ithaca, New York) |
| ABSTRACT | The present disclosure is directed to a system for displaying antigens. This system includes an outer membrane vesicle comprising a lipid bilayer and a synthetic antigen receptor comprising an outer membrane scaffold protein fused to a biotin-binding protein, where the outer membrane scaffold protein is incorporated in the lipid bilayer and the biotin-binding protein is displayed outside the outer membrane vesicle. Also disclosed are therapeutic compositions, nucleic acid constructs, expression vectors, and methods of eliciting an immune response in a subject. |
| FILED | Thursday, August 25, 2022 |
| APPL NO | 17/895245 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/385 (20130101) A61K 47/61 (20170801) A61K 47/543 (20170801) A61K 47/557 (20170801) Peptides C07K 14/005 (20130101) C07K 14/195 (20130101) C07K 16/44 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1037 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230083437 | Imani |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mohsen Imani (Irvine, California) |
| ABSTRACT | A hyperdimensional learning framework is disclosed with a variational encoder (VAE) module that is configured to generate variational autoencoding and to generate an unsupervised network that receives a data input and learns to predict the same data in an output layer. A hyperdimensional computing (HDC) learning module is coupled to the unsupervised network through a data bus, wherein the HDC learning module is configured to receive data from the VAE module and update an HDC model of the HDC learning module. The disclosed hyperdimensional learning framework provides a foundation for a new class of variational autoencoder that ensures that latent space has an ideal representation for hyperdimensional learning. Further disclosed is a hyperdimensional classification that directly operates over encoded data and enables robust single-pass and iterative learning while defining a first formal loss function and training method for HDC. |
| FILED | Thursday, August 25, 2022 |
| APPL NO | 17/895173 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/088 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230083502 | Imani |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mohsen Imani (Irvine, California) |
| ABSTRACT | Disclosed is a network-based hyperdimensional system having an encoder configured to receive input data and encode the input data using hyperdimensional computing to generate a hypervector having encoded data bits that represent the input data. The network-based hyperdimensional system further includes a decoder configured to receive the encoded data bits, decode the encoded data bits, and reconstruct the input data from the decoded data bits. In some embodiments, the encoder is configured for direct hyperdimensional learning on transmitted data with no need for data decoding by the decoder. |
| FILED | Thursday, August 25, 2022 |
| APPL NO | 17/895177 |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 13/1108 (20130101) Original (OR) Class H03M 13/1128 (20130101) H03M 13/6312 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230083757 | Palmowski et al. |
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| FUNDED BY |
|
| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincohn, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph Palmowski (Pasadena, California); Shane Farritor (Lincoln, Nebraska) |
| ABSTRACT | Disclosed herein are various robotic surgical devices and systems that include first and second elongate bodies, first and second driveshafts disposed through the second elongate body, and an in-line shoulder joint with a robotic arm coupled thereto. In certain implementations, the in-line shoulder joint has a differential yoke and a dual shaft disposed within the yoke lumen. |
| FILED | Friday, November 04, 2022 |
| APPL NO | 17/980665 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/30 (20160201) Original (OR) Class A61B 2034/305 (20160201) Manipulators; Chambers Provided With Manipulation Devices B25J 9/102 (20130101) B25J 9/126 (20130101) B25J 17/0258 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230084137 | Slagter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John Thomas Slagter (Grand Rapids, Michigan); Timothy Dykhuis (Grand Rapids, Michigan) |
| ASSIGNEE(S) | The Mackinac Technology Company (Grand Rapids, Michigan) |
| INVENTOR(S) | John Thomas Slagter (Grand Rapids, Michigan); Timothy Dykhuis (Grand Rapids, Michigan) |
| ABSTRACT | A blast-resistant window attachment, or retrofit window insulation system, wherein panes of polymer film, such as TPU or ETFE, are held in a roll-formed stainless steel frame to form a pane assembly. One or more pane assemblies are stacked to make a multilayer unit or are mounted in a robust polymer casing that is sized to fit the window frames of an existing building window or to attach to the wall of the building surrounding the window. The polymer film or films can absorb energy of a blast without breaking provided that the collective thickness of the film(s) is at least 20 mil, and preferably 24 mil or more. The casing is, preferably made from a high strength polymer, such as Acrylonitrile Butadiene Styrene, or a metal such as stainless steel. In experiments conducted by the Army Corp of Engineers, the retrofit window insulation system of the present invention, when securely bolted to the structural components of the building around the window, demonstrates a remarkable ability of the polymer film panes to absorb blast energy and mitigate secondary debris hazards. |
| FILED | Friday, July 29, 2022 |
| APPL NO | 17/876999 |
| CURRENT CPC | Buildings or Like Structures for Particular Purposes; Swimming or Splash Baths or Pools; Masts; Fencing; Tents or Canopies, in General E04H 9/06 (20130101) Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 5/12 (20130101) Original (OR) Class Blasting F42D 5/045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230084160 | Han et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | AT and T Intellectual Property I, L.P. (Atlanta, Georgia); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bo Han (Bridgewater, New Jersey); Vijay Gopalakrishnan (Edison, New Jersey); Muhammad Bilal Anwer (Branchburg, New Jersey); Zhi-Li Zhang (Eden Prairie, Minnesota); Yang Zhang (Saint Paul, Minnesota) |
| ABSTRACT | Systems and methods are disclosed for parallelizing service function chains. A method comprises receiving a sequential service function chain comprising a plurality of network functions, receiving a plurality of operations, determining at least two network functions are capable of being parallelized, aggregating operations of the plurality of operations associated with the at least two network functions into a network function segment, determining whether another network function is capable of being parallelized with the network function segment, based on the determining: aggregating an operation associated with the another network function into the network function segment when the another network function is capable of being parallelized with the network function segment, or pushing the network function segment as a completed segment of a hybrid service function chain when the another network function is not capable of being parallelized with the network function segment, and implementing the hybrid service function chain. |
| FILED | Monday, November 14, 2022 |
| APPL NO | 18/055233 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/5077 (20130101) G06F 9/45558 (20130101) G06F 2009/45595 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 41/0893 (20130101) Original (OR) Class H04L 45/64 (20130101) H04L 61/256 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230084321 | Yoshioka et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Valerie J. Yoshioka (Philadelphia, Pennsylvania); Jian Lu (Wynnewood, Pennsylvania); Zichen Tang (Philadelphia, Pennsylvania); Jicheng Jin (Philadelphia, Pennsylvania); Roy H. Olsson, III (Philadelphia, Pennsylvania); Bo Zhen (Merion Station, Pennsylvania) |
| ABSTRACT | Nonlinear on-chip optical devices using AlScN are described herein. In one aspect, an optical component having nonlinear characteristics can include a first substrate defining a refractive index; and a nonlinear layer, the nonlinear layer disposed on the first substrate, the nonlinear layer comprising an amount of scandium (Sc), and the nonlinear layer defining a refractive index that is higher than the refractive index of the first substrate. |
| FILED | Friday, July 29, 2022 |
| APPL NO | 17/877120 |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/353 (20130101) G02F 1/3556 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230084449 | Garay et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Edgar Felipe Garay (Atlanta, Georgia); Hua Wang (Atlanta, Georgia) |
| ABSTRACT | A dual-drive power amplifier (PA) where the PA core includes a differential pair of transistors M1 and M2 that are driven by a coupling network having two transmission-line couplers, where a first transmission line section of a coupler is configured to transmit an input signal Vin through to drive a gate of the opposite transistor, while the second transmission line section is grounded at one end and coupled with the first transmission line section such that a coupled portion αVin of the input signal Vin drives the source terminal of a corresponding transistor. The arrangement of the coupling network allows the source terminals to be driven below ground potential. Embodiments disclosed here further provide an input matching network, a driver, an inter-stage matching network, and an output network for practical implementation of the PA core. |
| FILED | Monday, October 10, 2022 |
| APPL NO | 18/045239 |
| CURRENT CPC | Amplifiers H03F 1/32 (20130101) H03F 1/0205 (20130101) H03F 1/565 (20130101) H03F 3/245 (20130101) Original (OR) Class H03F 2200/222 (20130101) H03F 2200/387 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230084726 | Walsworth et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); The President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ronald Walsworth (Newton, Massachusetts); Nithya Arunkumar (Waltham, Massachusetts); Connor Hart (Columbia, Maryland); Dominik Bucher (Puchheim, Germany); David Glenn (Cambridge, Massachusetts) |
| ABSTRACT | Systems and methods of quantum sensing include obtaining information regarding a target signal in electronic spin states of quantum defects in an ensemble of quantum defects, mapping the information regarding the target signal from the electronic spin states of the quantum defects to corresponding nuclear spin states associated with the quantum defects, applying a light pulse to the ensemble of quantum defects to reset the electronic spin states of the quantum defects, and repeating a readout stage a plurality of times within a readout duration. The readout stage includes mapping the information regarding the target signal back from the nuclear spin states to the corresponding electronic spin states and applying a data acquisition readout pulse to optically measure the electronic spin states of the quantum defects. |
| FILED | Wednesday, June 01, 2022 |
| APPL NO | 17/829551 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 24/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230085114 | Vam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Dayton Research Institute (Dayton, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Albert Vam (Springboro, Ohio); Giacomo Flora (Kettering, Ohio) |
| ABSTRACT | A liquid-liquid extraction system includes extraction stages, a pumping system, and a controller. Each extraction stage has a chamber, a primary input, a raffinate output, and an extract output. An input liquid (e.g., either a source liquid or raffinate from a preceding extraction stage, mixed with an extraction liquid) is presented to the chamber via the primary input. The chamber enables phase separation of liquid therein, into a raffinate and a extract, where the raffinate exits the separation vessel at the raffinate output, and the extract exits the separation vessel at the extract output. A level sensor is coupled to the chamber and the controller is operatively programmed to read an output of the level sensor, compare the output of the level sensor to a target, and cause the associated chamber to receive additional liquid if the output is lower than the target. |
| FILED | Tuesday, September 14, 2021 |
| APPL NO | 17/474989 |
| CURRENT CPC | Separation B01D 11/0484 (20130101) Original (OR) Class B01D 11/0492 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 21/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230085246 | Baer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eric Baer (Cleveland Heights, Ohio); Andrew Olah (Spencer, Ohio); Cong Zhang (Shaker Heights, Ohio); Gary Wnek (Cleveland, Ohio); Nathan McMullen (Cleveland, Ohio) |
| ABSTRACT | A method of producing high modulus and strength polymer materials includes compressive rolling a semicrystalline polymer material in at least two different axial directions of the material; and axially orienting at least a portion of the compressive rolled material to a draw ratio less than the ultimate elongation or the elongation % at break of the material. |
| FILED | Wednesday, September 14, 2022 |
| APPL NO | 17/944403 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 43/003 (20130101) B29C 45/0001 (20130101) B29C 48/07 (20190201) B29C 48/0011 (20190201) B29C 48/022 (20190201) B29C 59/04 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2023/065 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 7/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230085253 | STAUTH et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jason STAUTH (Hanover, New Hampshire); Yanqiao LI (Lebanon, New Hampshire) |
| ABSTRACT | A method for sequentially driving an electrical load includes (a) controlling N switching cells, where each of the N switching cells is electrically coupled to a respective one of N energy elements, such that the N energy elements are electrically coupled in a first topology to drive the electrical load with a first voltage, N being an integer greater than one, and (b) controlling the N switching cells such that N energy elements are electrically coupled in a second topology that is different from the first topology, to drive the electrical load with a second voltage that is different from the first voltage. |
| FILED | Wednesday, January 20, 2021 |
| APPL NO | 17/794586 |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 1/082 (20200101) H02J 7/0063 (20130101) H02J 2207/50 (20200101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/08 (20130101) H02M 3/07 (20130101) H02M 7/4837 (20210501) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230085393 | Crowe, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | James E. Crowe, Jr. (Nashville, Tennessee); Robert H. Carnanhan (Nashville, Tennessee); Pavlo Gilchuk (Nashville, Tennessee) |
| ABSTRACT | The present disclosure is directed to antibodies binding to and neutralizing Zika vims and methods for use thereof. |
| FILED | Monday, November 09, 2020 |
| APPL NO | 17/778160 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/31 (20130101) C07K 2317/34 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/185 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230085485 | Williams et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CITY OF HOPE (Duarte, California); THOMAS JEFFERSON UNIVERSITY (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John C. Williams (Monrovia, California); Cindy Zer (Duarte, California); Kendra N. Avery (Pasadena, California); Ulrich Rodeck (Philadelphia, Pennsylvania); Joshua M. Donaldson (Lumberion, New Jersey); Csaba Kari (Rosemont, California) |
| ABSTRACT | In one embodiment, a masked monoclonal antibody (mAb) is provided, the mAb, encoded by a nucleic acid sequence or an amino acid sequence molecule comprising a signal sequence, a masking epitope sequence, a linker sequence that is cleavable by a protease specific to a target tissue; and an antibody or a functional fragment thereof. In another embodiment, a masked monoclonal antibody (mAb) is provided, which includes a therapeutic mAb and a mask, the mask comprising protein A and protein L attached by a protease cleavable linker. |
| FILED | Monday, April 25, 2022 |
| APPL NO | 17/660603 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/55 (20170801) Original (OR) Class Peptides C07K 16/30 (20130101) C07K 16/2863 (20130101) C07K 2317/31 (20130101) C07K 2317/33 (20130101) C07K 2317/34 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/622 (20130101) C07K 2319/32 (20130101) C07K 2319/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230085492 | Khademhosseini et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alireza Khademhosseini (Cambridge, Massachusetts); Rahmi Oklu (Scottsdale, Arizona) |
| ABSTRACT | This disclosure relates to methods of using shear-thinning compositions in the treatment of a vascular disorders, cancers, infections, abscesses, and fistulas. |
| FILED | Tuesday, July 12, 2022 |
| APPL NO | 17/862959 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0019 (20130101) A61K 38/39 (20130101) Original (OR) Class A61K 47/02 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20230077624 | Kelley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Douglas H. Kelley (Rochester, New York); Ibrahim A. Mohammad (Rochester, New York) |
| ABSTRACT | Disclosed herein are systems and methods for obtaining efficient aluminum smelters. More specifically disclosed herein is a method comprising: applying an alternating current (AC) comprising an oscillatory current waveform to an electrolytic cell comprising an electrolyte for a first predetermined time, wherein waveform comprises an amplitude, frequency and/or phase that are predetermined to stabilize the electrolytic cell such that substantially no change in a current oscillation is observed in the electrolyte during electrolysis. Also disclosed herein is a system comprising an electrolytic cell, direct current and alternating current sources. The disclosed electrolytic cell exhibits substantially no change in oscillations present in the molten salt electrolyte over a predetermined period of time when the AC is provided to the electrolytic cell. |
| FILED | Wednesday, February 10, 2021 |
| APPL NO | 17/798651 |
| CURRENT CPC | Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor C25C 3/18 (20130101) C25C 3/20 (20130101) Original (OR) Class C25C 7/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230078124 | Coruzzi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | New York University (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gloria Coruzzi (New York, New York); Chia-Yi Cheng (Taipei, Taiwan) |
| ABSTRACT | Provided are machine learning methods for identifying genes that affect plant properties. Also provided are plant cell sand plants comprising genetic modifications that improve plant nitrogen utilization and increased biomass. Methods of making the modified plant cells and plants are also provided. |
| FILED | Wednesday, August 10, 2022 |
| APPL NO | 17/818968 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8218 (20130101) Original (OR) Class C12N 15/8261 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230078248 | Winslow et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Raimond L. Winslow (Baltimore, Maryland); Sridevi V. Sarma (McLean, Virginia); Ran Liu (Farmington, Connecticut) |
| ABSTRACT | Physiological time-series (PTS) data is sampled continuously from patients in the ICU. Here, this data is used to identify and prevent septic shock. The present invention applies statistical modeling and machine learning methods to implement an early warning policy for predicting those patients likely to transition from non-sepsis, early sepsis or sepsis into septic shock. Results demonstrate that the system and method of the present invention can provide higher sensitivity and specificity in this task than any other method reported to date. The present invention triggers an advanced early warning of this pending transition with median value 12.5 hours, giving ample opportunity for physicians to intervene to treat and prevent the patient from developing septic shock. |
| FILED | Monday, November 07, 2022 |
| APPL NO | 17/982076 |
| CURRENT CPC | Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 50/20 (20180101) Original (OR) Class G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230078543 | Wood et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nathaniel Joseph Wood (Columbus, Ohio); David John Hoelzle (Columbus, Ohio) |
| ABSTRACT | Estimation algorithms, methods, and systems are provided that estimate the internal temperatures inside of a part being built using a Finite Element Method (FEM)-based thermal model of Powder Bed Fusion (PBF) heat transfer. Closed-loop state estimation is applied to the problem of monitoring temperature fields within parts during the PBF build process. The PBF laser is very small, therefore, so too are the FEM elements nearby the laser. Thus, as the PBF laser moves, a region of high mesh density moves along with it as it progresses over a geometry. In an aspect, regions of high mesh density are predetermined for each time step according to a predefined schedule of laser movements. |
| FILED | Thursday, November 10, 2022 |
| APPL NO | 18/054535 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/28 (20210101) B22F 10/80 (20210101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 40/00 (20141201) B33Y 50/00 (20141201) Electric Digital Data Processing G06F 30/23 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230078860 | Biris et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexandru S. Biris (Little Rock, Arkansas); Ali T. Abdulhussein (Little Rock, Arkansas); Ganesh K. Kannarpady (Little Rock, Arkansas) |
| ABSTRACT | A method of synthesizing a medium for fast, selective oil-water separation and/or oil absorption comprises providing a toluene solution containing a polymer or a polymer mixture; immersing porous wool-like structure (PW) in the toluene solution for a period of time; and removing the immersed PW from the toluene solution, and heat-treating the immersed PW to obtain the medium comprising polymer-modified PW, wherein the polymer or the polymer mixture is adapted such that the medium is a superwetting material that is superhydrophobic and superoleophilic under water or salty water. |
| FILED | Tuesday, October 04, 2022 |
| APPL NO | 17/959415 |
| CURRENT CPC | Separation B01D 17/0202 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/205 (20130101) B01J 20/262 (20130101) B01J 20/3078 (20130101) B01J 20/3204 (20130101) B01J 20/3272 (20130101) B01J 20/28009 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/40 (20130101) C02F 1/48 (20130101) C02F 1/288 (20130101) Original (OR) Class C02F 2101/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230078917 | Pal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Anamitra Pal (Tempe, Arizona); John Patterson (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Anamitra Pal (Tempe, Arizona); John Patterson (Tempe, Arizona) |
| ABSTRACT | A time-synchronized micro-scale continuous point-on-wave (CPoW) measurement device, referred to as micro-CPoW, is provided. The distribution system is an integral part of the electric power system, but not much is known about how it behaves in real-time. To address this knowledge gap, a low-cost, time-synchronized, CPoW measurement system is designed, built, and characterized herein. The purpose of the micro-CPoW measurement device is to monitor the instantaneous electric current flowing through a distribution line in real time. Detection of harmonics, identification of incipient fault conditions, and general power quality monitoring are typical uses for the measured information. Because the micro-CPoW measurement device is self-powered by the line current and communicates wirelessly, it can be installed without ground-mounted instrument transformers, low-voltage power sources, or communications cabling. Thus, this particular design of CPoW module is intended to be installed directly on a power line without the need for external support equipment. |
| FILED | Thursday, September 01, 2022 |
| APPL NO | 17/929150 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 19/0092 (20130101) Original (OR) Class G01R 19/1659 (20130101) G01R 19/2513 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/001 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230079529 | BALDESI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Luca BALDESI (Boston, Massachusetts); Francesco RESTUCCIA (Boston, Massachusetts); Tommaso MELODIA (Newton, Massachusetts) |
| ABSTRACT | Methods and systems are provided for frequency sharing in RANs using artificial intelligence including scanning, by a spectrum classification unit (SCU) of a channel-aware reactive mechanism (ChARM) app, a plurality of frequencies associated with ongoing communication, classifying, by a DNN of the SCU, I/Q samples of each of the scanned frequencies, the DNN executable via the one or more of the near-RT RIC, the DU, the RU, or combinations thereof, receiving, at a policy decision unit (PDU) from the SCU, the classified frequencies, applying, by the PDU, an embedded policy to the classified frequencies, transmitting commands from the PDU to a DU for making changes to the ongoing communication according to the applied policy, receiving, at a control interface implemented in the DU, the commands transmitted by the PDU, and changing, by the DU according to the commands, an operating parameter of a RU. |
| FILED | Wednesday, September 14, 2022 |
| APPL NO | 17/944687 |
| CURRENT CPC | Wireless Communication Networks H04W 16/14 (20130101) Original (OR) Class H04W 24/02 (20130101) H04W 72/0453 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230079919 | Claussen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan Claussen (Ames, Iowa); Bolin Chen (San Jose, California); Carmen L. Gomes (Ames, Iowa) |
| ABSTRACT | Apparatus, systems, and methods for tuning the structure, conductivity, and/or wettability of laser induced graphene for a variety of functions including but not limited to multiplexed open microfluidic environmental biosensing and energy storage devices. Aspects of this invention introduce a one-step, mask-free process to create, pattern, and tune laser-induced graphene (LIG) with a ubiquitous CO2 laser or other laser. The laser parameters are adjusted to create LIG with different electrical conductivity, surface morphology, and surface wettability without the need for post chemical modification. This can be done with a single lasing. By optionally introducing a second (or third, fourth, or more) lasing(s), the LIG characteristics can be changed in just the same one step of using the laser scribing without other machines or sub-systems. One example is a second lasing with the same laser sub-system at low laser power, wherein the wettability of the LIG can be significantly altered. Such films presented unique superhydrophobicity owing to the combination of the micro/nanotextured structure and the removal of the hydrophilic oxygen-containing functional groups. The ability to tune the wettability of LIG while retaining high electrical conductivity and mechanical robustness allows rational design of LIG based on application. |
| FILED | Monday, September 12, 2022 |
| APPL NO | 17/931228 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 3/502715 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/351 (20151001) B23K 26/364 (20151001) Original (OR) Class B23K 26/0622 (20151001) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/36 (20130101) H01G 11/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230080178 | Hajjar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jerome F. Hajjar (Newton, Massachusetts); Yujie Yan (Nanjing, China PRC) |
| ABSTRACT | Embodiments automatically assess, e.g., quantify dimensions of, cracks in real-world objects. Amongst other examples, such functionality can be used to identify structural problems in bridges and buildings. An example implementation maps pixels in an image of a real-world object to corresponding points in point cloud data of the real-world object. In turn, a patch in the image data that includes a crack is identified by processing, using a classifier, the pixels with the corresponding points mapped. Pixels in the patch that correspond to the crack are then identified based on one or more features of the image. Real-world dimensions of the crack are determined using the identified pixels in the patch corresponding to the crack. |
| FILED | Friday, September 02, 2022 |
| APPL NO | 17/929466 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/894 (20200101) Image Data Processing or Generation, in General G06T 7/0002 (20130101) Original (OR) Class G06T 7/13 (20170101) G06T 7/55 (20170101) G06T 2207/10028 (20130101) G06T 2207/10032 (20130101) G06T 2207/20021 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30108 (20130101) G06T 2207/30244 (20130101) Image or Video Recognition or Understanding G06V 10/803 (20220101) G06V 20/17 (20220101) G06V 20/176 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230080312 | Marcus et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Oregon (Eugene, Oregon) |
| ASSIGNEE(S) | University of Oregon (Eugene, Oregon) |
| INVENTOR(S) | Andrew H. Marcus (Eugene, Oregon); Claire S. Albrecht (Eugene, Oregon); John W. Maurer (Eugene, Oregon); Patrick J. Herbert (Eugene, Oregon); Dylan Heussman (Eugene, Oregon) |
| ABSTRACT | Swept polarization optical beams are directed to a sample to produce fluorescence. typical as a plurality of single photon detection events. Based on frequencies associated with the polarization sweeps, orientation of a sample can be determined. Using polarization sweeps at first and second frequencies and wavelength, donor fluorophore orientation can be established based on the first frequency and wavelength and acceptor orientation can be established based on a sum or difference of the first and second frequencies and the second wavelength. |
| FILED | Tuesday, September 13, 2022 |
| APPL NO | 17/931870 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6408 (20130101) G01N 21/6428 (20130101) G01N 21/6445 (20130101) Original (OR) Class G01N 21/6458 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230080380 | Hajjar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jerome F. Hajjar (Newton, Massachusetts); Yujie Yan (Nanjing, China PRC) |
| ABSTRACT | Embodiments generate finite element meshes (FEMs) representing real-world objects. An example embodiment partitions point cloud data of a real-world object into groups of points where each group corresponds to a component of the real-world object. In turn, such an embodiment generates a respective geometric representation of each group of points and generates a respective FEM of each respective geometric representation generated. The generated FEMs are combined to create a FEM representing the real-world object. Such functionality can be used to build FEMs of as built real-world objects, such as bridges and buildings. These FEMs can, in turn, be used in simulations to determine behavior of the as-built real-world objects and/or determine design changes. |
| FILED | Friday, September 02, 2022 |
| APPL NO | 17/929580 |
| CURRENT CPC | Electric Digital Data Processing G06F 30/23 (20200101) Original (OR) Class Image Data Processing or Generation, in General G06T 17/205 (20130101) G06T 19/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230080414 | Yazden-Shahmorad et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Azadeh Yazden-Shahmorad (Seattle, Washington); Julien Bloch (Seattle, Washington); Alexander Greaves-Tunnell (Seattle, Washington); Eric Shea-Brown (Seattle, Washington); Ali Shojaie (Seattle, Washington); Zaid Harchaoui (Seattle, Washington) |
| ABSTRACT | Cortical network structure that mediates response to brain stimulation, and associated systems and methods are disclosed herein. In one embodiment, a method for brain stimulation includes: delivering an input stimulus to an area of the brain, via a cortical implant; in response to delivering the input stimulus, generating neural signals in the brain; and generating a predicted outcome of the input stimulus. The predicted outcome is based on a set of data derived from a model that combines: protocol features that are brain agnostic, and network features that are based on interactions between neural nodes of the brain. |
| FILED | Thursday, September 01, 2022 |
| APPL NO | 17/901496 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0529 (20130101) Original (OR) Class A61N 1/36082 (20130101) A61N 1/36139 (20130101) A61N 5/067 (20210801) A61N 5/0601 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230080523 | DHINOJWALA et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ali DHINOJWALA (Akron, Ohio); Ming XIAO (Cambridge, Massachusetts); Ziying HU (Wilmette, Illinois); Matthew SHAWKEY (Ghent, Belgium); Nathan GIANNESCHI (Wilmette, Illinois) |
| ASSIGNEE(S) | THE UNIVERSITY OF AKRON (Akron, Ohio) |
| INVENTOR(S) | Ali DHINOJWALA (Akron, Ohio); Ming XIAO (Cambridge, Massachusetts); Ziying HU (Wilmette, Illinois); Matthew SHAWKEY (Ghent, Belgium); Nathan GIANNESCHI (Wilmette, Illinois) |
| ABSTRACT | In various embodiments, the present invention is directed to a facile one-pot reverse emulsion process to assemble core-shell nanoparticles (CS-SMNPs) into bright and noniridescent photonic supraballs. In one or more embodiments, the present invention is directed to core-shell nanoparticles having an inner high refractive index (RI) core and an outer low RI shell. In one or more embodiment, the present invention includes core-shell nanoparticles using high RI (˜1.74) melanin cores and low-RI (˜1.45) silica shells. In various embodiments, these nanoparticles may be self-assembled into bright and noniridescent supraballs using a scalable one-pot reverse emulsion process. According to various embodiments of the present invention, it is possible to generate a full spectrum of structural colors with the combination of only two ingredients, synthetic melanin and silica. |
| FILED | Tuesday, September 13, 2022 |
| APPL NO | 17/943667 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/18 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 67/0005 (20130101) C09B 67/0007 (20130101) C09B 69/104 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230080531 | HWANG et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of lllinois (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael HWANG (Urbana, Illinois); Rashid BASHIR (Urbana, Illinois); Mohammad HEIRANIAN (Urbana, Illinois); Sungwoo NAM (Urbana, Illinois); Narayan ALURU (Urbana, Illinois); Arend VAN DER ZANDE (Urbana, Illinois); Catherine J. MURPHY (Urbana, Illinois); Jonghyun CHOI (Urbana, Illinois); Yerim KIM (Urbana, Illinois) |
| ABSTRACT | Provided are biosensors, systems and related methods of using the biosensors and systems. The biosensor comprises a field-effect transistor (FET) having a crumpled geometry to effectively increase the detection sensitivity of a target molecule in an ionic solution. A FET having a crumpled semiconductor material channel can form a π-π interaction with single stranded DNA (ssDNA) for amplification detection applications. Increasing amount of ssDNA in an amplification reaction solution is incorporated into an amplified double stranded DNA, with increasing amplification, resulting in a lower amount of ssDNA primers. The FET is contacted with the amplified solution to electrically detect an amount of ssDNA primer in the amplified solution, thereby detecting amplification based on a decreased amount of ssDNA bound to the FET. Also provided are biosensors that can detect biomolecules more generally, such as protein, polypeptides, polynucleotides, or small molecules. |
| FILED | Friday, February 26, 2021 |
| APPL NO | 17/800461 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) C12Q 1/6876 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4145 (20130101) G01N 27/4146 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/772 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230081364 | Babakhani et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Aydin Babakhani (Los Angeles, California); Hamed Rahmani (Belle Mead, New Jersey); Hidemasa Mitsui (Santa Clara, California) |
| ABSTRACT | Systems and methods for utilizing a small form-factor, wirelessly powered transceiver are disclosed. In one embodiment, a wireless powered transceiver includes a receive antenna configured to receive a receive signal, a transmit antenna configured to transmit a transmit signal, a power harvesting system including a rectifier circuit configured convert radio frequency energy from the receive signal into DC (direct current) voltage, and a power management unit (PMU) configured to set the operating mode and biasing condition of the receive and transmit circuitry blocks and provide DC voltage from the receive circuitry block to the transmit circuitry block to maintain a minimum voltage, a receiver circuitry block configured to provide energy from the receive signal to the power harvesting system, and a transmitter circuitry block including a data modulator circuit, the data modulator circuit configured to generate the transmit signal using DC voltage received from the power management unit. |
| FILED | Tuesday, September 06, 2022 |
| APPL NO | 17/929959 |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/001 (20200101) H02J 50/27 (20160201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230081541 | Grayson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew Allen Grayson (Evanston, Illinois); Chulin Wang (Evanston, Illinois); Claire Cecelia Onsager (Stoughton, Wisconsin); Can Cenap Aygen (Chicago, Illinois); Charles M. Costakis (Evanston, Illinois); Lauren E. Lang (Boulder, Colorado); Andreas Tzavelis (Demarest, New Jersey); John Ashley Rogers (Wilmette, Illinois); Suzan van der Lee (Evanston, Illinois) |
| ABSTRACT | The disclosed 2-D resistance tomographic imaging method optimizes computation speed for performing electrical impedance tomography using a model-space with a minimal number of orthonormal polynomial basis functions to describe discernable features in the 2-D resistance tomographic image, determining a minimal number of contacts to take fewer measurements than available information based on the number of basis functions, selecting a subset of rows of a matrix of calculated sensitivity coefficients to form a square Jacobian matrix for a linearized forward problem to be solved and inversion of the linear forward problem, and solving an inverse problem based on the square Jacobian matrix by performing at least one iteration of a Newton's method solve. |
| FILED | Tuesday, October 25, 2022 |
| APPL NO | 18/049551 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0536 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 11/003 (20130101) G06T 2211/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230081567 | Babakhani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Aydin Babakhani (Los Angeles, California); Seyedmohammadreza Razavian (San Diego, California); Mahdi Assefzadeh (Winter Springs, Florida); Mostafa Hosseini (Los Angeles, California) |
| ABSTRACT | Systems and methods for modulation and demodulation using a micro-Doppler effect are described. In an embodiment, the method includes radiating, using a picosecond pulse generator with an antenna, a train of THz pulses that form a frequency comb, where the frequency comb is reflected from an object such that the frequency several tones in the frequency comb are shifted based on the speed of the object and demodulating the reflected frequency comb to recover a THz Doppler signature of the object. |
| FILED | Monday, September 12, 2022 |
| APPL NO | 17/931301 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/28 (20130101) G01S 7/4095 (20210501) G01S 13/505 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230081896 | Ryu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Byunghoon Ryu (Ann Arbor, Michigan); Jay Chen (Ann Arbor, Michigan); Xiaogan Liang (Ann Arbor, Michigan); Katsuo Kurabayashi (Ann Arbor, Michigan); Young Geun Park (Ann Arbor, Michigan) |
| ABSTRACT | Provided herein is an air monitoring system with a venturi pump including an air supply passageway, a sample passageway, and a discharge passageway, the discharge passageway in fluid communication with the air supply passageway and the sample passageway, and a detection device including a biochip, a light emitting source, a photodetector, and a controller electronically coupled to the photodetector. Also provided herein is a photonic biogel and uses thereof for spectroscopic detection of airborne pathogens. |
| FILED | Thursday, September 15, 2022 |
| APPL NO | 17/945558 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/59 (20130101) G01N 33/56916 (20130101) G01N 33/56983 (20130101) Original (OR) Class G01N 2201/127 (20130101) G01N 2333/165 (20130101) G01N 2333/245 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230083183 | Lynn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin); University of Puerto Rico (San Juan, Puerto Rico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Lynn (Middleton, Wisconsin); Claribel Acevedo-Velez (Mayaguez, Puerto Rico); Oscar H. Piñeres-Quiñones (Mayaguez, Puerto Rico) |
| ABSTRACT | Devices and methods for using changes in the orientation of micrometer sized dispersed liquid crystal domains to detect or quantify analytes in a test sample, including amphiphilic analytes, are disclosed. The dispersed liquid crystal domains are defined by an interface, and one or more nanoparticles or nanoparticle-containing complexes are adsorbed to the interface. As a result of the adsorption of the nanoparticles or nanoparticle-containing complexes at the interface, the microdomains are stabilized, and resist coalescing for extended periods of time, unlike previously known devices using liquid crystal emulsions for analyte detection. When the dispersed liquid crystal microdomains are exposed to the test sample, any changes in the orientation of the liquid crystal microdomains (such as from the bipolar to radial) are detected. Such changes in orientation signal the presence of analyte in the test sample, and the proportion of liquid crystal microdomains exhibiting the change in orientation is correlated with the quantity of analyte in the test sample. The nanoparticle used, the amphiphile used in the nanoparticle-containing complex, or both may be selected to optimize the sensitivity and/or selectivity of the device for a given analyte. |
| FILED | Tuesday, September 06, 2022 |
| APPL NO | 17/903434 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/47 (20130101) G01N 21/64 (20130101) G01N 31/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230083394 | DELISA et al. |
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| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew P. DELISA (Ithaca, New York); Kevin WEYANT (Ithaca, New York) |
| ABSTRACT | The present disclosure is directed to a system for displaying antigens. This system includes an outer membrane vesicle comprising a lipid bilayer and a synthetic antigen receptor comprising an outer membrane scaffold protein fused to a biotin-binding protein, where the outer membrane scaffold protein is incorporated in the lipid bilayer and the biotin-binding protein is displayed outside the outer membrane vesicle. Also disclosed are therapeutic compositions, nucleic acid constructs, expression vectors, and methods of eliciting an immune response in a subject. |
| FILED | Thursday, August 25, 2022 |
| APPL NO | 17/895245 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/385 (20130101) A61K 47/61 (20170801) A61K 47/543 (20170801) A61K 47/557 (20170801) Peptides C07K 14/005 (20130101) C07K 14/195 (20130101) C07K 16/44 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1037 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230083977 | Shue et al. |
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| FUNDED BY |
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| APPLICANT(S) | Worcester Polytechnic Institute (Worcester, Washington) |
| ASSIGNEE(S) | Worcester Polytechnic Institute (Worcester, Massachusetts) |
| INVENTOR(S) | Craig Shue (Worcester, Massachusetts); Julian Lanson (Brighton, Massachusetts); Lane Harrison (Worcester, Massachusetts); Yunsen Lei (Worcester, Massachusetts); Matthew Puentes (Malden, Massachusetts) |
| ABSTRACT | Embodiments of the innovation relate to, in a webserver device, a method for identifying a logic defect in an application. The method comprises establishing a webserver instance of the webserver device with a client device, the webserver instance of the webserver device having a corresponding set of client device permissions; receiving a content request from the client device associated with the webserver instance of the webserver device; detecting a violation of a permission of the set of client device permissions associated with the webserver instance of the webserver device; identifying at least one webserver function associated with the violation of the permission of the set of client device permissions; and displaying a visual identification of the at least one webserver function associated with the violation of the permission of the set of client device permissions. |
| FILED | Wednesday, September 07, 2022 |
| APPL NO | 17/939254 |
| CURRENT CPC | Electric Digital Data Processing G06F 8/70 (20130101) G06F 21/44 (20130101) Original (OR) Class G06F 2221/2141 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230084088 | Song et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xin Song (Durham, North Carolina); John Reif (Durham, North Carolina) |
| ABSTRACT | Methods and systems for photopatterning and miniaturization. In some examples, a method for patterning a substrate includes irradiating a pattern onto the substrate with ultraviolet light and heating the substrate, causing the substrate and the pattern to shrink in at least one dimension to form a miniaturized pattern on the substrate. In some examples, a system for patterning a substrate includes an ultraviolet light source, a heater, and a controller configured for irradiating a pattern onto the substrate with ultraviolet light and heating the substrate, causing the substrate and the pattern to shrink in at least one dimension to form a miniaturized pattern on the substrate. |
| FILED | Friday, February 05, 2021 |
| APPL NO | 17/797765 |
| CURRENT CPC | Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/38 (20130101) G03F 7/2008 (20130101) G03F 7/2047 (20130101) Original (OR) Class G03F 7/2051 (20130101) G03F 7/70008 (20130101) G03F 7/70525 (20130101) G03F 7/70875 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230084160 | Han et al. |
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| FUNDED BY |
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| APPLICANT(S) | AT and T Intellectual Property I, L.P. (Atlanta, Georgia); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bo Han (Bridgewater, New Jersey); Vijay Gopalakrishnan (Edison, New Jersey); Muhammad Bilal Anwer (Branchburg, New Jersey); Zhi-Li Zhang (Eden Prairie, Minnesota); Yang Zhang (Saint Paul, Minnesota) |
| ABSTRACT | Systems and methods are disclosed for parallelizing service function chains. A method comprises receiving a sequential service function chain comprising a plurality of network functions, receiving a plurality of operations, determining at least two network functions are capable of being parallelized, aggregating operations of the plurality of operations associated with the at least two network functions into a network function segment, determining whether another network function is capable of being parallelized with the network function segment, based on the determining: aggregating an operation associated with the another network function into the network function segment when the another network function is capable of being parallelized with the network function segment, or pushing the network function segment as a completed segment of a hybrid service function chain when the another network function is not capable of being parallelized with the network function segment, and implementing the hybrid service function chain. |
| FILED | Monday, November 14, 2022 |
| APPL NO | 18/055233 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/5077 (20130101) G06F 9/45558 (20130101) G06F 2009/45595 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 41/0893 (20130101) Original (OR) Class H04L 45/64 (20130101) H04L 61/256 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230084321 | Yoshioka et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Valerie J. Yoshioka (Philadelphia, Pennsylvania); Jian Lu (Wynnewood, Pennsylvania); Zichen Tang (Philadelphia, Pennsylvania); Jicheng Jin (Philadelphia, Pennsylvania); Roy H. Olsson, III (Philadelphia, Pennsylvania); Bo Zhen (Merion Station, Pennsylvania) |
| ABSTRACT | Nonlinear on-chip optical devices using AlScN are described herein. In one aspect, an optical component having nonlinear characteristics can include a first substrate defining a refractive index; and a nonlinear layer, the nonlinear layer disposed on the first substrate, the nonlinear layer comprising an amount of scandium (Sc), and the nonlinear layer defining a refractive index that is higher than the refractive index of the first substrate. |
| FILED | Friday, July 29, 2022 |
| APPL NO | 17/877120 |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/353 (20130101) G02F 1/3556 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230084483 | Tajin et al. |
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| FUNDED BY |
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| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Md Abu Saleh Tajin (Philadelphia, Pennsylvania); Kapil R. Dandekar (Philadelphia, Pennsylvania) |
| ABSTRACT | The growing research interest in passive RFID (Radio Frequency Identification)-based devices and sensors in a diverse group of applications calls for flexibility in reader antenna performance. A low-cost, easy-to-fabricate, and pattern reconfigurable UHF (Ultra High Frequency) RFID reader antenna in the RFID ISM band (902-928 MHz in the US) may offer a 54 MHz bandwidth (890 944 MHz) and 8.9 dBi maximum gain. The reconfigurable antenna can radiate four electronically switchable radiation beams in the azimuth plane. The antenna may be LHCP (Left Hand Circularly Polarized) with axial ratio (AR) in the ranging from 0.45 dB to 7 dB in the RFID ISM band. |
| FILED | Thursday, September 01, 2022 |
| APPL NO | 17/823976 |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/10316 (20130101) Original (OR) Class Antennas, i.e Radio Aerials H01Q 1/2216 (20130101) H01Q 9/0428 (20130101) H01Q 21/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230084825 | GIBBONS et al. |
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| FUNDED BY |
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| APPLICANT(S) | PRAIRIE AQUATECH LLC (Brookings, South Dakota) |
| ASSIGNEE(S) | PRAIRIE AQUATECH LLC (Brookings, South Dakota) |
| INVENTOR(S) | WILLIAM GIBBONS (BROOKINGS, South Dakota); Michael L Brown (Volga, South Dakota) |
| ABSTRACT | The present invention describes a bio-based process to produce high quality protein concentrate (HQPC) by converting plant derived celluloses into bioavailable protein via aerobic incubation, including the use of such HQPC so produced as a nutrient, including use as a fish meal replacement in aquaculture diets. |
| FILED | Monday, August 29, 2022 |
| APPL NO | 17/897746 |
| CURRENT CPC | Protein Compositions for Foodstuffs; Working-up Proteins for Foodstuffs; Phosphatide Compositions for Foodstuffs A23J 1/14 (20130101) A23J 1/125 (20130101) Original (OR) Class A23J 1/148 (20130101) Fodder A23K 10/14 (20160501) A23K 10/38 (20160501) A23K 20/147 (20160501) A23K 40/20 (20160501) A23K 40/25 (20160501) A23K 50/80 (20160501) Technologies for Adaptation to Climate Change Y02A 40/818 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230085246 | Baer et al. |
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| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eric Baer (Cleveland Heights, Ohio); Andrew Olah (Spencer, Ohio); Cong Zhang (Shaker Heights, Ohio); Gary Wnek (Cleveland, Ohio); Nathan McMullen (Cleveland, Ohio) |
| ABSTRACT | A method of producing high modulus and strength polymer materials includes compressive rolling a semicrystalline polymer material in at least two different axial directions of the material; and axially orienting at least a portion of the compressive rolled material to a draw ratio less than the ultimate elongation or the elongation % at break of the material. |
| FILED | Wednesday, September 14, 2022 |
| APPL NO | 17/944403 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 43/003 (20130101) B29C 45/0001 (20130101) B29C 48/07 (20190201) B29C 48/0011 (20190201) B29C 48/022 (20190201) B29C 59/04 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2023/065 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 7/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230085275 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wenzhi Li (Miami, Florida); Arun Thapa (Miami, Florida) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Wenzhi Li (Miami, Florida); Arun Thapa (Miami, Florida) |
| ABSTRACT | Vertically aligned carbon nanotubes (VACNTs) (e.g., multi-walled VACNTs and methods of synthesizing the same are provided. VACNTs can be synthesized on nickel foam (Ni—F), for example by using a plasma-enhanced chemical vapor deposition (PECVD) technique. A wet chemical method can then be used to coat on the VACNTs a layer of nanoparticles, such as tin oxide (SnO2) nanoparticles. |
| FILED | Friday, October 07, 2022 |
| APPL NO | 17/938832 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/48 (20130101) H01M 4/366 (20130101) H01M 4/0428 (20130101) H01M 4/583 (20130101) Original (OR) Class H01M 10/0525 (20130101) H01M 2004/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230085492 | Khademhosseini et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alireza Khademhosseini (Cambridge, Massachusetts); Rahmi Oklu (Scottsdale, Arizona) |
| ABSTRACT | This disclosure relates to methods of using shear-thinning compositions in the treatment of a vascular disorders, cancers, infections, abscesses, and fistulas. |
| FILED | Tuesday, July 12, 2022 |
| APPL NO | 17/862959 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0019 (20130101) A61K 38/39 (20130101) Original (OR) Class A61K 47/02 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230085510 | Dagan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Research Foundation of the City University of New York (New York, New York); Atolla Tech LLC (Rockville Centre, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Morann Sonia Dagan (New York, New York); Andrii Golovin (New York, New York); Fred Moshary (New Brunswick, New Jersey) |
| ABSTRACT | A method for detecting an airborne object. Electromagnetic radiation is emitted from a transmitter to overlap with a receiver's field of view. When an airborne object enters the field of view, the electromagnetic radiation interacts with moving airfoils on the airborne object to produce reflected and scattered electromagnetic radiation. The reflected and scattered electromagnetic radiation is analyzed to detect, classify and/or determine the orientation of the airborne object. |
| FILED | Thursday, December 31, 2020 |
| APPL NO | 17/790285 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4816 (20130101) G01S 7/4817 (20130101) G01S 17/88 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20230077350 | Haile et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois); University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sossina M. Haile (Evanston, Illinois); Sihyuk Choi (Evanston, Illinois); Christopher James Kucharczyk (Evanston, Illinois); Yangang Liang (Richland, Washington); Xiaohang Zhang (North Potomac, Maryland); Ichiro Takeuchi (Laurel, Maryland) |
| ABSTRACT | Materials for electrochemical cells are provided. BaZr0.4Ce0.4M0.2O3 compounds, where M represents one or more rare earth elements, are provided for use as electrolytes. PrBa0.5Sr0.5Co2−xFexO5+δ is provided for use as a cathode. Also provided are electrochemical cells, such as protonic ceramic fuel cells, incorporating the compounds as electrolytes and cathodes. |
| FILED | Friday, November 11, 2022 |
| APPL NO | 17/985218 |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 25/02 (20130101) C01G 25/006 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/861 (20130101) H01M 4/8657 (20130101) H01M 4/9033 (20130101) Original (OR) Class H01M 4/9066 (20130101) H01M 8/126 (20130101) H01M 8/1213 (20130101) H01M 8/1246 (20130101) H01M 8/1253 (20130101) H01M 2008/1293 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230077400 | Arges et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher George Arges (Baton Rouge, Louisiana); Varada Menon Palakkal (Baton Rouge, Louisiana); Matthew Leo Jordan (Baton Rouge, Louisiana) |
| ABSTRACT | Various examples related to resin wafer technologies including ionomers and resin wafers with solution processable ionomers and their production are provided. In one example, a wafer includes an ion conducting layer having ion-exchange resin particles and an ionomer binder coating the ion-exchange resin particles. The ionomer binder can bind the ion-exchange resin particles together in the ion conducting layer. In another example, the wafer can contain water dissociation catalysts for promoting water-splitting in the wafers. |
| FILED | Friday, February 05, 2021 |
| APPL NO | 17/797926 |
| CURRENT CPC | Separation B01D 61/46 (20130101) B01D 67/0079 (20130101) B01D 69/145 (20130101) Original (OR) Class B01D 71/52 (20130101) B01D 2325/42 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/04 (20130101) B01J 35/0013 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/4695 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230077771 | Sozer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yilmaz Sozer (Peninsula, Ohio); Anik Chowdhury (Akron, Ohio); Md Ehsanul Haque (Akron, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yilmaz Sozer (Peninsula, Ohio); Anik Chowdhury (Akron, Ohio); Md Ehsanul Haque (Akron, Ohio) |
| ABSTRACT | A method of operating a motor includes providing an electric system coupled with the motor, the electric system including parallel inverter legs; subjecting the motor to a first interleaving angle when the electric system is under a first condition; and subjecting the motor to a second interleaving angle different from the first interleaving angle when the electric system is under a second condition; wherein the steps of subjecting the motor to the first interleaving angle and subjecting the motor to the second interleaving angle occur within continuous operation of the electric system and the motor. |
| FILED | Thursday, September 08, 2022 |
| APPL NO | 17/940448 |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 38/14 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/10 (20160201) Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 21/05 (20130101) Original (OR) Class H02P 25/03 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230077940 | Xu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Ting Xu (Berkeley, California); Christopher A. DelRe (Berkeley, California) |
| ABSTRACT | Compositions comprise synergistic enzyme mixtures, and related methods, to realize near-complete depolymerization in biodegradable polymer/additive blends. |
| FILED | Friday, September 09, 2022 |
| APPL NO | 17/941026 |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 11/105 (20130101) Original (OR) Class C08J 2367/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230078467 | Komarasamy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mageshwari Komarasamy (Richland, Washington); Scott A. Whalen (West Richland, Washington); Brian K. Milligan (Richland, Washington) |
| ABSTRACT | Shear-assisted extrusion assemblies are provided. The assemblies can include a billet containing assembly containing a billet comprising a billet outer material and a billet inner material in at least one cross-section; a tool operably engaged with the billet; an extrudate receiving channel configured to receive extrudate from the tool, wherein the extrudate comprises extruded outer material and extruded inner material in at least one cross-section, the extruded outer material being the same material as the billet outer material, and the extruded inner material being the same as the billet inner material. Methods for producing multi-material shear-assisted extrudate are also provided. |
| FILED | Wednesday, September 14, 2022 |
| APPL NO | 17/944932 |
| CURRENT CPC | Manufacture of Metal Sheets, Wire, Rods, Tubes or Profiles, Otherwise Than by Rolling; Auxiliary Operations Used in Connection With Metal-working Without Essentially Removing Material B21C 23/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230078811 | ACHINIVU et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California); National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ezinne C. ACHINIVU (Alexandria, Virginia); John M. GLADDEN (Alameda, California); Hemant CHOUDHARY (Emeryville, California); Blake A. SIMMONS (San Francisco, California) |
| ABSTRACT | The present invention provides for a method to produce a sugar from a biomass, the method comprising: (a) providing a first mixture comprising a solubilized biomass and a distillable acid-base conjugate salt (DABCS) or deep eutectic solvent (DES), wherein (i) the DABCS is a protic ionic liquid (PIL) or a protic salt comprising a DABCS cation and a DABCS anion, and (ii) the DES is any combination of Lewis or Brønsted acid and base comprising any anionic and/or cationic species that have sufficient vapor pressure so that it can be readily distilled; and (b) distilling at least part of the DABCS from the first mixture in order to separate the at least part of the DABCS from the first mixture. |
| FILED | Thursday, February 18, 2021 |
| APPL NO | 17/800871 |
| CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/02 (20130101) Original (OR) Class C12P 19/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230080881 | PALMSTROM et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Axel Finn PALMSTROM (Golden, Colorado); Tomas LEIJTENS (Emerald Hills, California); Joseph Jonathan BERRY (Boulder, Colorado); David Todd MOORE (Arvada, Colorado) |
| ABSTRACT | The present disclosure relates to a device that includes a first layer that includes at least one of a semiconducting material, a hole transport material (HTM), and/or an electron transport material (ETM), a second layer, and a third layer that includes a material that is at least one of transparent or conductive, where the second layer is positioned between the first layer and the third layer, the first layer, the second layer, and the third layer are in electrical contact with each other, and the third layer has a first thickness between greater than zero nm and about 100 nm. In some embodiments of the present disclosure, the semiconducting material may include a perovskite. |
| FILED | Friday, August 12, 2022 |
| APPL NO | 17/819384 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0037 (20130101) H01L 51/0043 (20130101) Original (OR) Class H01L 51/0046 (20130101) H01L 51/422 (20130101) H01L 51/4253 (20130101) H01L 51/5072 (20130101) H01L 2251/303 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230081364 | Babakhani et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Aydin Babakhani (Los Angeles, California); Hamed Rahmani (Belle Mead, New Jersey); Hidemasa Mitsui (Santa Clara, California) |
| ABSTRACT | Systems and methods for utilizing a small form-factor, wirelessly powered transceiver are disclosed. In one embodiment, a wireless powered transceiver includes a receive antenna configured to receive a receive signal, a transmit antenna configured to transmit a transmit signal, a power harvesting system including a rectifier circuit configured convert radio frequency energy from the receive signal into DC (direct current) voltage, and a power management unit (PMU) configured to set the operating mode and biasing condition of the receive and transmit circuitry blocks and provide DC voltage from the receive circuitry block to the transmit circuitry block to maintain a minimum voltage, a receiver circuitry block configured to provide energy from the receive signal to the power harvesting system, and a transmitter circuitry block including a data modulator circuit, the data modulator circuit configured to generate the transmit signal using DC voltage received from the power management unit. |
| FILED | Tuesday, September 06, 2022 |
| APPL NO | 17/929959 |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/001 (20200101) H02J 50/27 (20160201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230081699 | Terrani et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kurt A. Terrani (Oak Ridge, Tennessee); Andrew T. Nelson (Oak Ridge, Tennessee) |
| ABSTRACT | A method for manufacturing a nuclear fuel compact is provided. The method includes forming an additive structure, consolidating a fuel matrix around the additive structure, and thermally processing the fuel matrix to form a fuel compact in which the additive structure is encapsulated therein. The additive structure optionally includes a vertical segment and a plurality of arm segments that extend generally radially from the vertical segment for conducting heat outwardly toward an exterior of the fuel compact. In addition to improving heat transfer, the additive structure may function as burnable absorbers, and may provide fission product trapping. |
| FILED | Friday, September 02, 2022 |
| APPL NO | 17/901967 |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Nuclear Reactors G21C 3/18 (20130101) Original (OR) Class G21C 3/048 (20190101) G21C 3/623 (20130101) G21C 21/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230081786 | Joshi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Vineet V. Joshi (Richland, Washington); Scott A. Whalen (West Richland, Washington); Curt A. Lavender (Richland, Washington); Glenn J. Grant (Benton City, Washington); MD. Reza-E-Rabby (Richland, Washington); Aashish Rohatgi (Richland, Washington); Jens T. Darsell (West Richland, Washington) |
| ABSTRACT | A process for forming extruded products using a device having a scroll face configured to apply a rotational shearing force and an axial extrusion force to the same preselected location on material wherein a combination of the rotational shearing force and the axial extrusion force upon the same location cause a portion of the material to plasticize, flow and recombine in desired configurations. This process provides for a significant number of advantages and industrial applications, including but not limited to extruding tubes used for vehicle components with 50 to 100 percent greater ductility and energy absorption over conventional extrusion technologies, while dramatically reducing manufacturing costs. |
| FILED | Friday, November 11, 2022 |
| APPL NO | 17/985611 |
| CURRENT CPC | Manufacture of Metal Sheets, Wire, Rods, Tubes or Profiles, Otherwise Than by Rolling; Auxiliary Operations Used in Connection With Metal-working Without Essentially Removing Material B21C 23/002 (20130101) B21C 23/08 (20130101) B21C 23/142 (20130101) B21C 23/215 (20130101) B21C 23/218 (20130101) B21C 25/02 (20130101) Original (OR) Class B21C 27/00 (20130101) B21C 29/003 (20130101) B21C 33/00 (20130101) B21C 37/155 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 2301/058 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230082559 | Eidelpes et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho); UT-Battelle, LLC (Oak Ridge, Tennessee); Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Elmar F. Eidelpes (Idaho Falls, Idaho); Joshua J. Jarrell (Idaho Falls, Idaho); Robert A. Hall (Lenoir City, Tennessee); William J. Marshall (Knoxville, Tennessee); Harold A. Adkins, JR. (Richland, Washington); Brian M. Hom (Richland, Washington) |
| ABSTRACT | Various embodiments relate to devices for transporting high-assay low-enriched uranium (HALEU). A device may include at least one section, wherein each section of the at least one section includes a number of storage tubes. Each storage tube, which is configured to receive and hold a container, extends from adjacent a first end of the section toward second, opposite end of the section. Each section further includes a number of flux traps, wherein each storage tube of the number of storage tubes is at least partially surrounded by a flux trap of the number of flux traps Associated systems are also disclosed. |
| FILED | Wednesday, September 15, 2021 |
| APPL NO | 17/447712 |
| CURRENT CPC | Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 5/12 (20130101) G21F 5/14 (20130101) Original (OR) Class G21F 5/015 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230082570 | RENDALL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | JOSEPH D. RENDALL (Oak Ridge, Tennessee); KASHIF NAWAZ (Knoxville, Tennessee); WILLIAM E. ASHER (Chicago, Illinois); AHMED F. ELATAR (Knoxville, Tennessee); JIAN SUN (Knoxville, Tennessee); JAMIESON BRECHTL (Knoxville, Tennessee); XIAOLI LIU (Knoxville, Tennessee); KEJU AN (Knoxville, Tennessee); MINGKAN ZHANG (Knoxville, Tennessee) |
| ABSTRACT | A medium for energy storage includes a plurality of capsules. Each capsule contains a phase changing material (PCM) configured to undergo a liquid-solid phase transition at a solidification temperature, TS. The PCM undergoes a relative volume change due to the phase transition. A shell is filled with the PCM. The shell contains a first heat-conducting material, and is configured to comply to the relative volume change. The relative volume change is configured to cause a buoyancy force, which acts on the capsule when the capsule is disposed in water at a water temperature, TW, to be larger than the capsule's weight for Tw>Ts, and equal to or smaller than the capsule's weight for Tw<Ts. The Ts can be within ±5° F. of a design water temperature To at the outlet of a water tank. The capsule can be neutrally buoyant in water at To. |
| FILED | Thursday, August 18, 2022 |
| APPL NO | 17/890791 |
| CURRENT CPC | Domestic- or Space-heating Systems, e.g Central Heating Systems; Domestic Hot-water Supply Systems; Elements or Components Therefor F24D 11/002 (20130101) Original (OR) Class F24D 2220/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20230082643 — SURFACE TREATMENT FOR COLLOIDAL STABILITY OF IN-SOLUTION LIGAND EXCHANGED QUANTUM DOTS
| US 20230082643 | Nakotte et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tom Nakotte (Dublin, California); Jinkyu Han (San Ramon, California); Anna Hiszpanski (Pleasanton, California) |
| ABSTRACT | A product includes a solution comprising Ag2Se quantum dots in a solvent. The solution is colloidally stable for at least one week. A product includes a solid layer formed of Ag2Se quantum dots. The layer is at least 100 nm thick. The layer is physically characterized by a substantial absence of defects therein. A process includes forming a solution of Ag2Se quantum dots and adding at least acetonitrile to the solution. The process further includes separating the Ag2Se quantum dots from the solution and washing the Ag2Se quantum dots at least two times in a solution comprising at least acetonitrile. The process further includes redispersing the washed Ag2Se quantum dots in a nonpolar solvent to create a colloidal suspension. |
| FILED | Monday, September 13, 2021 |
| APPL NO | 17/473712 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 19/007 (20130101) Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black; C09C 1/00 (20130101) C09C 3/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230082826 | Agustsson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RadiaBeam Technologies, LLC (Santa Monica, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ronald Agustsson (Venice, California); Salime Boucher (Santa Monica, California); Sergey Kutsaev (Santa Monica, California) |
| ABSTRACT | A particle accelerator can include a first waveguide portion and a second waveguide portion. The first waveguide portion can include a first plurality of cell portions and a first iris portion that is disposed between two of the first plurality of cell portions. The first iris portion can include a first portion of an aperture such that the aperture is configured to be disposed about a beam axis. The first waveguide portion can further include a first bonding surface. The second waveguide portion can include a second plurality of cell portions and a second iris portion that is disposed between two of the second plurality of cell portions. The second iris portion can include a second portion of the aperture. The second waveguide portion can include a second bonding surface. |
| FILED | Thursday, August 11, 2022 |
| APPL NO | 17/886212 |
| CURRENT CPC | Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 7/18 (20130101) H05H 7/22 (20130101) H05H 9/02 (20130101) Original (OR) Class H05H 2007/225 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230083647 | Mann et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicholas R. Mann (Idaho Falls, Idaho); Kevin P. Carney (Idaho Falls, Idaho) |
| ABSTRACT | A structure—for use in simulating radioactive contamination environments—comprises fragments encapsulated within a substrate material. The fragments comprise radioactive isotopes with moderate half-lives. To form such structures, the fragments are encapsulated within the at least one substrate material. In a method of simulating a radioactive contamination environment, multiple removable structures, such as the aforementioned structures, are selectively placed in a facility, and may be subsequently removed, stored, and reused. |
| FILED | Tuesday, May 03, 2022 |
| APPL NO | 17/661849 |
| CURRENT CPC | Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 9/305 (20130101) Conversion of Chemical Elements; Radioactive Sources G21G 4/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230083860 | Timpson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Erik Joseph Timpson (Lee's Summit, Missouri); Justin M. Schlitzer (Stillwell, Kansas); Thomas Matthew Selter (Blue Springs, Missouri); Michael Walsh (Overland Park, Kansas) |
| ABSTRACT | Systems and methods for building passive and active electronics with diamond-like carbon (DLC) coatings are provided herein. DLC may be layered upon substrates to form various components of electronic devices. Passive components such as resistors, capacitors, and inductors may be built using DLC as a dielectric or as an insulating layer. Active components such as diodes and transistors may be built with the DLC acting substantially like a semiconductor. The amount of sp2 and sp3 bonded carbon atoms may be varied to modify the properties of the DLC for various electronic components. |
| FILED | Tuesday, September 14, 2021 |
| APPL NO | 17/474879 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/51 (20130101) Original (OR) Class H01L 29/84 (20130101) H01L 29/868 (20130101) H01L 29/4916 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230084061 | Byers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Kyle J. Byers (Kansas City, Missouri); Louis Brown (Kansas City, Missouri); Daniel John Salzman (Lee's Summit, Missouri) |
| ABSTRACT | A method of tuning an electrically small antenna comprising a radiating element and a support structure comprises applying a force to the support structure to change a shape or a dimension of the radiating element to increase or decrease a frequency at which the electrically small antenna resonates. |
| FILED | Thursday, September 08, 2022 |
| APPL NO | 17/940800 |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/36 (20130101) H01Q 9/14 (20130101) Original (OR) Class H01Q 9/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230084320 | Antao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dion S. Antao (College Station, Texas); Ruisong Wang (College Station, Texas) |
| ABSTRACT | In an embodiment, the present disclosure pertains to a method of forming a self-assembled monolayer coating on a surface of a substrate. In general, the method includes polishing the substrate, cleaning the substrate, and creating a plurality of bonding sites on the surface of the substrate for head groups of an organofunctional silane molecule to bond. In some embodiments, the creating includes at least one of a liquid-phase chemistry process or a dry plasma chemistry process. In some embodiments, the method further includes coating the substrate with a silane coating solution. In some embodiments, the coating is performed in a controlled environment. In some embodiments, the controlled environment includes an anhydrous environment free of at least one of water or moisture. In a further embodiment, the present disclosure pertains to a heat transfer composition having a coating thereon applied via the methods of the present disclosure. |
| FILED | Tuesday, September 06, 2022 |
| APPL NO | 17/903079 |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 3/12 (20130101) B05D 3/044 (20130101) B05D 7/54 (20130101) B05D 7/148 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/002 (20130101) C09D 7/20 (20180101) C09D 127/18 (20130101) C09D 183/08 (20130101) Original (OR) Class Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 5/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230085175 | Smalls et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Eden GeoPower, Inc. (Somerville, Massachusetts) |
| ASSIGNEE(S) | Eden GeoPower, Inc. (Somerville, Massachusetts) |
| INVENTOR(S) | Paris Smalls (Boston, Massachusetts); Mehrdad Mehrvand (Boston, Massachusetts); Ammar Alali (Cambridge, Massachusetts); Marybeth Lundquist (Somerville, Massachusetts) |
| ABSTRACT | The present disclosure describes electro-hydrofracturing (E-HF) using electrically conductive proppants and methods for hydraulic fracturing using electrically conductive proppants. |
| FILED | Monday, August 15, 2022 |
| APPL NO | 17/887822 |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 8/64 (20130101) C09K 8/70 (20130101) C09K 8/665 (20130101) C09K 8/805 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 36/001 (20130101) E21B 43/267 (20130101) E21B 49/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230085289 | Kiefer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Seth M. Kiefer (Kansas City, Missouri); Phillip C. Davis (Kansas City, Missouri) |
| ABSTRACT | A caul for debulking a composite part broadly includes opposing first and second surfaces, a plurality of through-holes, and a coating. The first surface may have a curvature complementary to a shape of the composite part. The through-holes pass through the caul from the first surface to the second surface. The coating may be a chemically inert material to ensure the caul does not affect the composite part. The caul is configured to be positioned against the composite part for debulking. The caul may be made out of silicone rubber or any other suitable material and may be reusable. |
| FILED | Friday, September 09, 2022 |
| APPL NO | 17/941590 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 33/3842 (20130101) B29C 70/342 (20130101) B29C 70/544 (20210501) Original (OR) Class Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2819/00 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 20230078593 | Smith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Barry T. Smith (Egg Harbor City, New Jersey); John Brady (Medford, New Jersey); Jeffrey Barber (Vineland, New Jersey) |
| ABSTRACT | Examples are directed toward systems and methods relating to collecting and analyzing samples. For example, a system includes a cold trap that directly collects a sample. The cold trap operates to serve as a collection filter while the system draws in a flow across the cold trap. A thermal heater, coupled to the cold trap, flash heats the cold trap to produce a released sample from the cold trap at a release concentration. An analyzer entrains the released sample at the release concentration into a sampling flow of the analyzer for analysis. |
| FILED | Wednesday, September 07, 2022 |
| APPL NO | 17/939676 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/623 (20210101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 49/0031 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230079634 | Reynolds et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Matthew S. Reynolds (Seattle, Washington); Andreas Pedross-Engel (Seattle, Washington); Claire Watts (Seattle, Washington); Sandamali Devadithya (Seattle, Washington) |
| ABSTRACT | Examples of imaging systems are described herein which may implement microwave or millimeter wave imaging systems. Examples described may implement partitioned inverse techniques which may construct and invert a measurement matrix to be used to provide multiple estimates of reflectivity values associated with a scene. The processing may be partitioned in accordance with a relative position of the antenna system and/or a particular beamwidth of an antenna. Examples described herein may perform an enhanced resolution mode of imaging which may steer beams at multiple angles for each measurement position. |
| FILED | Tuesday, September 20, 2022 |
| APPL NO | 17/933805 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/89 (20130101) G01S 13/90 (20130101) Original (OR) Class G01S 13/888 (20130101) G01S 13/9004 (20190501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230080152 | Oxley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Jimmie Oxley (Narragansett, Rhode Island); James L. Smith (Narragansett, Rhode Island); Alexander Yevdokimov (Norwich, Connecticut); Kevin Colizza (Collegeville, Pennsylvania) |
| ABSTRACT | Examples are directed toward collecting, by a LC-MS device, a full scan of ion chromatograms of a sample. The LC-MS device determines observed ions contained in the full scan, based on mass-to-charge ratios (m/z), and determines, for a formation curve of an observed ion, a formation point at which fifty percent of the observed ion has formed. The LC-MS device determines a fragmentation curve of a precursor ion, based on a fragmentation point of the fragmentation curve equivalent to the formation point at which fifty percent of the precursor ion has fragmented, and identifies the precursor ion by referencing the LC-MS library to confirm that the observed ion is a product of the fragmentation of the precursor ion. The LC-MS device indicates a goodness of fit between the fragmentation curve, as observed, and a model fragmentation curve, as stored in the LC-MS library. |
| FILED | Friday, July 29, 2022 |
| APPL NO | 17/877064 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/7233 (20130101) G01N 30/8631 (20130101) G01N 30/8693 (20130101) G01N 30/8696 (20130101) G01N 2030/027 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0036 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230080178 | Hajjar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jerome F. Hajjar (Newton, Massachusetts); Yujie Yan (Nanjing, China PRC) |
| ABSTRACT | Embodiments automatically assess, e.g., quantify dimensions of, cracks in real-world objects. Amongst other examples, such functionality can be used to identify structural problems in bridges and buildings. An example implementation maps pixels in an image of a real-world object to corresponding points in point cloud data of the real-world object. In turn, a patch in the image data that includes a crack is identified by processing, using a classifier, the pixels with the corresponding points mapped. Pixels in the patch that correspond to the crack are then identified based on one or more features of the image. Real-world dimensions of the crack are determined using the identified pixels in the patch corresponding to the crack. |
| FILED | Friday, September 02, 2022 |
| APPL NO | 17/929466 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/894 (20200101) Image Data Processing or Generation, in General G06T 7/0002 (20130101) Original (OR) Class G06T 7/13 (20170101) G06T 7/55 (20170101) G06T 2207/10028 (20130101) G06T 2207/10032 (20130101) G06T 2207/20021 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30108 (20130101) G06T 2207/30244 (20130101) Image or Video Recognition or Understanding G06V 10/803 (20220101) G06V 20/17 (20220101) G06V 20/176 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20230077922 | Mireles et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The National Aeronautics and Space Administration (Washington, District of Columbia); EOS North America (Novi, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Omar Mireles (Huntsville, Alabama); Zachary Jones (Montreal, Canada); Maryna Ienina (Pflugerville, Texas); Ankit Saharan (Pflugerville, Texas) |
| ABSTRACT | In one aspect, a method for manufacturing a lattice structure for use as a propulsion catalyst includes: (a) providing a powder bed of one or more metal powder materials, (b) heating a portion of the powder bed to a temperature sufficient to melt the one or more metal powder materials, (c) forming a layer of the lattice structure, wherein the layer is formed by melting the one or more metal powder materials in a predefined pattern, (d) constructing the lattice structure, wherein the lattice structure is constructed by repeating steps (a)-(c) for each of a plurality of layers of the lattice structure until the lattice structure is constructed, and (e) removing excess materials from the constructed lattice structure. |
| FILED | Thursday, August 04, 2022 |
| APPL NO | 17/803491 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 35/04 (20130101) B01J 37/0018 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230079367 | HUANG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yuping HUANG (Norwood, New Jersey); Yong Meng SUA (Fort Lee, New Jersey); Jiuyi ZHANG (Palisades Park, New Jersey); Jiayang CHEN (Jersey City, New Jersey); Jeevanandha RAMANATHAN (Jersey City, New Jersey) |
| ABSTRACT | A spectroscope using single-photon counters and a chip-integrated lithium niobate micro-ring filter to measure the atmospheric CO2 absorption spectrum passively is disclosed. By thermo-optically sweeping the filter over 150 pm and referencing the resulting photon counts to a bypass channel, the absorption spectrum can be sampled at an ultrahigh-resolution of 6 pm. The spectroscope can be a part of a ground-based field system, wherein the CO2 absorption through the atmosphere can be characterized by counting the solar photons across the absorption line around 1572.02 nm, which agrees well with its transmission spectrum at standard atmospheric pressure. |
| FILED | Wednesday, September 14, 2022 |
| APPL NO | 17/944965 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/31 (20130101) Original (OR) Class G01N 33/0027 (20130101) G01N 2201/08 (20130101) G01N 2201/06113 (20130101) Optical Elements, Systems, or Apparatus G02B 6/29338 (20130101) G02B 6/29383 (20130101) G02B 6/29395 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230079426 | Ferguson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Michael Ian Ferguson (Pine Mountain Club, California) |
| ABSTRACT | A method and system provide the ability to compile computer source code. The source code is pre-processed to generate pure source code that includes definitions required for interpretation. The pure source code is formalized in a compiler, into assembly language that is processor specific. The formalization includes determining a set of two or more optimization routines, randomly selecting a selected optimization routine from the set of two or more optimization routines, and applying the selected optimization routine to each segment of the pure source code in a serialized manner. An executable binary file is then output and executed based on the formalized pure source code. |
| FILED | Friday, September 02, 2022 |
| APPL NO | 17/929522 |
| CURRENT CPC | Electric Digital Data Processing G06F 8/447 (20130101) Original (OR) Class G06F 8/4441 (20130101) G06F 11/3696 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230083041 | Zhanaidarova et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Almagul Zhanaidarova (La Jolla, California); Clifford P. Kubiak (Del Mar, California); Valerie Scott (Altadena, California); Emmanuelle Despagnet-Ayoub (Pasadena, California) |
| ABSTRACT | The present disclosure provides methods, compositions, devices, systems and uses that pertain to the electrochemical reduction of CO2 to CO. The application presents a class of electrodes, incorporating molecular catalysts in nanostructures, for robust and efficient electrochemical systems, specifically, selective and robust hybrid electrodes, by incorporating a rhenium (Re) catalyst into the structure of highly porous heterogeneous materials. These electrodes can be scaled up to desired manufacturing dimensions due to their robust nature and methods of preparation. |
| FILED | Tuesday, March 31, 2020 |
| APPL NO | 17/599030 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/23 (20210101) C25B 11/054 (20210101) C25B 11/065 (20210101) C25B 11/085 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20230078124 | Coruzzi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | New York University (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gloria Coruzzi (New York, New York); Chia-Yi Cheng (Taipei, Taiwan) |
| ABSTRACT | Provided are machine learning methods for identifying genes that affect plant properties. Also provided are plant cell sand plants comprising genetic modifications that improve plant nitrogen utilization and increased biomass. Methods of making the modified plant cells and plants are also provided. |
| FILED | Wednesday, August 10, 2022 |
| APPL NO | 17/818968 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8218 (20130101) Original (OR) Class C12N 15/8261 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230079687 | ELDER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Andrew S. ELDER (University Park, Pennsylvania); Ryan J. ELIAS (University Park, Pennsylvania); John N. COUPLAND (University Park, Pennsylvania); Helene HOPFER (University Park, Pennsylvania) |
| ABSTRACT | Alkylresorcinols (ARs) are a homologous series of natural phenolipids extracted from rye bran which have shown antioxidant activity in bulk oils and oil-in-water emulsions. This application is directed to their use in low-moisture foods using crackers as a model system. ARs (153 μmol) inhibited lipid oxidation reactions based on delayed formation of primary and secondary products of lipid oxidation compared to a control treatment, and were more effective than α-tocopherol. The antioxidant activity of ARs of compound of Formula (I) increased as alkyl chain length increased, with optimum activity at alkyl chain length C23:0. There was no effect of alkyl chain length on rate of AR loss. ARs are effective antioxidants in low-moisture foods likely due to their hydrophobic nature, which allowed them to localize in the lipid phase, the purported site of lipid oxidation in the model cracker system. |
| FILED | Wednesday, August 31, 2022 |
| APPL NO | 17/900503 |
| CURRENT CPC | Treatment, e.g Preservation, of Flour or Dough, e.g by Addition of Materials; Baking; Bakery Products; Preservation Thereof A21D 13/80 (20170101) Edible Oils or Fats, e.g Margarines, Shortenings, Cooking Oils A23D 9/06 (20130101) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 3/349 (20130101) Original (OR) Class Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230079919 | Claussen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan Claussen (Ames, Iowa); Bolin Chen (San Jose, California); Carmen L. Gomes (Ames, Iowa) |
| ABSTRACT | Apparatus, systems, and methods for tuning the structure, conductivity, and/or wettability of laser induced graphene for a variety of functions including but not limited to multiplexed open microfluidic environmental biosensing and energy storage devices. Aspects of this invention introduce a one-step, mask-free process to create, pattern, and tune laser-induced graphene (LIG) with a ubiquitous CO2 laser or other laser. The laser parameters are adjusted to create LIG with different electrical conductivity, surface morphology, and surface wettability without the need for post chemical modification. This can be done with a single lasing. By optionally introducing a second (or third, fourth, or more) lasing(s), the LIG characteristics can be changed in just the same one step of using the laser scribing without other machines or sub-systems. One example is a second lasing with the same laser sub-system at low laser power, wherein the wettability of the LIG can be significantly altered. Such films presented unique superhydrophobicity owing to the combination of the micro/nanotextured structure and the removal of the hydrophilic oxygen-containing functional groups. The ability to tune the wettability of LIG while retaining high electrical conductivity and mechanical robustness allows rational design of LIG based on application. |
| FILED | Monday, September 12, 2022 |
| APPL NO | 17/931228 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 3/502715 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/351 (20151001) B23K 26/364 (20151001) Original (OR) Class B23K 26/0622 (20151001) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/36 (20130101) H01G 11/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20230077885 | Weisbart et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States GOVERNMENT As represented By The Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard H. Weisbart (Washington, District of Columbia); Robert N. Nishimura (Sepulveda, California) |
| ABSTRACT | The invention provides methods for selective targeting of live cells, which have undergone or are undergoing radiation or chemotherapy, at a site of interest with a cell-penetrating polypeptide. In one embodiment of the invention, the method comprises contacting the live cells with a cell-penetrating polypeptide comprising cell-penetrating determinants so that the cell-penetrating polypeptide binds extracellular DNA near or around the live cells so as to form a complex or association therewith such that the complex or associated polypeptide-DNA so bound bind the live cells and penetrates the live cells thereby selectively targeting live cells at a site of interest with a cell-penetrating polypeptide. |
| FILED | Friday, September 16, 2022 |
| APPL NO | 17/946094 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6843 (20170801) A61K 2039/505 (20130101) Peptides C07K 16/18 (20130101) C07K 16/44 (20130101) Original (OR) Class C07K 2317/77 (20130101) C07K 2317/622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230084914 | Potkay |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph A. Potkay (Ann Arbor, Michigan) |
| ABSTRACT | Disclosed herein are rolled-membrane microfluidic diffusion devices and corresponding methods of manufacture. Also disclosed herein are three-dimensionally printed microfluidic devices and corresponding methods of manufacture. Optionally, the disclosed microfluidic devices can function as artificial lung devices. |
| FILED | Thursday, November 10, 2022 |
| APPL NO | 17/984408 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/1623 (20140204) A61M 1/1698 (20130101) Original (OR) Class A61M 2205/0244 (20130101) A61M 2205/8206 (20130101) A61M 2207/00 (20130101) A61M 2209/088 (20130101) Separation B01D 63/005 (20130101) B01D 63/065 (20130101) B01D 69/02 (20130101) B01D 69/04 (20130101) B01D 69/12 (20130101) B01D 71/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 20230080146 | MONROE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher MONROE (Ellicott City, Maryland); Marko CETINA (College Park, Maryland); Norbert LINKE (Stevenson, Maryland); Shantanu DEBNATH (College Park, Maryland) |
| ABSTRACT | The disclosure describes various aspects of optical control of atomic quantum bits (qubits) for phase control operations. More specifically, the disclosure describes methods for coherently controlling quantum phases on atomic qubits mediated by optical control fields, applying to quantum logic gates, and generalized interactions between qubits. Various attributes and settings of optical/qubit interactions (e.g., atomic energy structure, laser beam geometry, polarization, spectrum, phase, background magnetic field) are identified for imprinting and storing phase in qubits. The disclosure further describes how these control attributes are best matched in order to control and stabilize qubit interactions and allow extended phase-stable quantum gate sequences. |
| FILED | Thursday, May 06, 2021 |
| APPL NO | 17/313450 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Optical Computing Devices; G06E 1/00 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230082448 | Pan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bowen Pan (Cambridge, Massachusetts); Rameswar Panda (Medford, Massachusetts); Camilo Luciano Fosco (Buenos Aires, Argentina); Rogerio Schmidt Feris (West Hartford, Connecticut); Aude Jeanne Oliva (Cambridge, Massachusetts) |
| ABSTRACT | For each convolution layer of a plurality of convolution layers of a convolutional neural network (CNN), apply an input-dependent policy network to determine: a first fraction of input feature maps to the given layer for which first corresponding output feature maps are to be fully computed by the layer; and a second fraction of input feature maps to the layer for which second corresponding output feature maps are not to be fully computed, but to be reconstructed from the first corresponding output feature maps. Fully computing the first corresponding output feature maps and reconstruct the second corresponding output feature maps. For a final one of the convolution layers of the plurality of convolution layers of the neural network, input the first corresponding output feature maps and the second corresponding output feature maps to an output layer to obtain an inference result. |
| FILED | Wednesday, September 15, 2021 |
| APPL NO | 17/476437 |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6256 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class G06N 3/0454 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 20230078195 | Stephen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Victoria K. Stephen (Burke, Virginia); Elke Reuning-Elliott (Rosslyn, Virginia) |
| ABSTRACT | A distribution item is disclosed. The distribution item includes a first item comprising a container having an outer surface defining an enclosed space. A computer-readable code is disposed on the outer surface. The computer-readable code is associated with a first level entity. The first item also includes destination information associated with a second level entity disposed on the outer surface. The distribution item also includes one or more second items removably positioned within the enclosed space of the first item. Each of the one or more second items includes the computer-readable code associated with the first level entity. |
| FILED | Monday, November 21, 2022 |
| APPL NO | 18/057346 |
| CURRENT CPC | Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 3/10 (20130101) B07C 3/14 (20130101) Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus B42D 5/025 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/1413 (20130101) G06K 7/1417 (20130101) G06K 7/10861 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0833 (20130101) Ticket-issuing Apparatus; Fare-registering Apparatus; Franking Apparatus G07B 2017/00475 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230083482 | NAGY et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael A. NAGY (Warrenton, Virginia); Dirk H. SATTLER (Gainesville, Virginia) |
| ABSTRACT | Systems, methods, and devices for designating a location for a delivery item that is being sorted by an operator. The operator scans the delivery address of the item using a particular scanner. Using the delivery address and other information from the scanner that was used, the system determines a sort output location for the item and identifies an indicator device (e.g., an LED device) that corresponds to the sort output location. The system then commands the indicator device to present or display a designator. For example, the indicator device may be commanded to illuminate a light, such as an LED. The operator of the scanner then places the item at the location corresponding to the illuminated light designator. |
| FILED | Friday, November 18, 2022 |
| APPL NO | 18/056950 |
| CURRENT CPC | Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 3/008 (20130101) B07C 3/14 (20130101) Original (OR) Class B07C 3/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
| US 20230083139 | VABNICK |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Federal Bureau of Investigation (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Federal Bureau of Investigation, Dept. of Justice (Washington, District of Columbia) |
| INVENTOR(S) | Ian B. VABNICK (Fredericksburg, Virginia) |
| ABSTRACT | Provided are methods and related devices for disrupting an explosive device using a propellant driven disrupter (PDD) that propels a rounded projectile (RP) toward an explosive device. The RP travels along a linear trajectory and impacts the target, including a barrier portion of the explosive device. The impacting between the RP and barrier forms a composite projectile via a solid state weld between a portion of the barrier and the RP distal end, thereby minimizing or avoiding spall and fragment generation into the explosive device. The projectile traverses a penetration distance along the linear trajectory, or a defined-angle relative thereto, to disrupt the explosive device without unwanted explosive detonation. |
| FILED | Tuesday, July 12, 2022 |
| APPL NO | 17/862940 |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 21/02 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 12/76 (20130101) F42B 12/745 (20130101) F42B 33/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Interior (DOI)
| US 20230082501 | Bhalekar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Prakash Bhalekar (Minneapolis, Minnesota); Mustafa F. Kaddoura (Minneapolis, Minnesota); Natasha C. Wright (Minneapolis, Minnesota); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Prakash Bhalekar (Minneapolis, Minnesota); Mustafa F. Kaddoura (Minneapolis, Minnesota); Natasha C. Wright (Shakopee, Minnesota) |
| ABSTRACT | A system includes an evaporator having sensors and selectable operational parameters and a controller configured to receive data and determine operational configuration for the evaporator. Selectable parameters relate to system heating, liquid flow rate, air flow rate, and environmental data. |
| FILED | Monday, September 12, 2022 |
| APPL NO | 17/931520 |
| CURRENT CPC | Separation B01D 1/22 (20130101) Original (OR) Class B01D 1/0064 (20130101) B01D 1/0082 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/008 (20130101) C02F 1/08 (20130101) C02F 1/048 (20130101) C02F 2201/005 (20130101) C02F 2209/02 (20130101) C02F 2209/38 (20130101) C02F 2209/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 20230083257 | Pillai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Texas A and M University System (College Station, Texas); Chevron U.S.A. Inc. (Richmond, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Suresh D. Pillai (College Station, Texas); David Staack (College Station, Texas); John Lassalle (College Station, Texas); Thomas Hoelen (Berkeley, California); Paul Bireta (Houston, Texas) |
| ABSTRACT | A method of waste treatment includes treating partially-dewatered matrix with a first electron-beam radiation dose. The treated partially-dewatered matrix is transferred to a digester where the treated partially-dewatered matrix is subjected to anaerobic digestion. Biogas is recovered from the treated partially-dewatered matrix during the anaerobic digestion. The treated partially-dewatered matrix is dried and subjected to a second electron-beam radiation dose. |
| FILED | Thursday, December 31, 2020 |
| APPL NO | 17/790336 |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 9/00 (20130101) Original (OR) Class C02F 2101/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Reconnaissance Office (NRO)
| US 20230079634 | Reynolds et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Matthew S. Reynolds (Seattle, Washington); Andreas Pedross-Engel (Seattle, Washington); Claire Watts (Seattle, Washington); Sandamali Devadithya (Seattle, Washington) |
| ABSTRACT | Examples of imaging systems are described herein which may implement microwave or millimeter wave imaging systems. Examples described may implement partitioned inverse techniques which may construct and invert a measurement matrix to be used to provide multiple estimates of reflectivity values associated with a scene. The processing may be partitioned in accordance with a relative position of the antenna system and/or a particular beamwidth of an antenna. Examples described herein may perform an enhanced resolution mode of imaging which may steer beams at multiple angles for each measurement position. |
| FILED | Tuesday, September 20, 2022 |
| APPL NO | 17/933805 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/89 (20130101) G01S 13/90 (20130101) Original (OR) Class G01S 13/888 (20130101) G01S 13/9004 (20190501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20230080265 | Lai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Synbal, Inc. (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | ChenYen Lai (Escondido, California); Oscar Alvarez (San Marcos, California); Kurt Jarnagin (San Mateo, California) |
| ABSTRACT | The present disclosure relates to genetically modified non-human animals (e.g., genetically-modified mice or rodents) that express a hACE2 and/or hTMPRRS2 under control of the mouse promoter and the genetically modified non-human animal does not express native ACE2 and/or hTMPRRS2. The present disclosure also relates to methods of generating the genetically-modified animals (e.g., genetically modified mice or rodents), and methods of using the genetically modified non-human animals (e.g., genetically modified mice or rodents) described herein. |
| FILED | Monday, June 27, 2022 |
| APPL NO | 17/850770 |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0278 (20130101) Original (OR) Class A01K 2207/15 (20130101) A01K 2227/105 (20130101) A01K 2267/0337 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/485 (20130101) C12N 9/6424 (20130101) C12N 15/8509 (20130101) C12N 2015/8581 (20130101) Enzymes C12Y 304/17023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 20230078017 | Jones et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wolfspeed, Inc. (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Evan Jones (Durham, North Carolina); Saptha Sriram (Cary, North Carolina); Kyle Bothe (Cary, North Carolina) |
| ABSTRACT | A semiconductor device includes a substrate having an upper surface including a recess region, a semiconductor structure on the substrate, a portion of the semiconductor structure within the recess region, and a gate contact, a drain contact, and a source contact on the semiconductor structure. The recess region does not vertically overlap the drain contact or the source contact. |
| FILED | Thursday, September 16, 2021 |
| APPL NO | 17/477004 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/778 (20130101) H01L 29/1075 (20130101) Original (OR) Class H01L 29/7831 (20130101) H01L 29/8124 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230079399 | YANG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF H (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shyh Ming YANG (Doylestown, Pennsylvania); David J. MALONEY (Points of Rocks, Maryland); Natalia MARTINEZ (Rockville, Maryland); Adam YASGAR (Washington, District of Columbia); Anton SIMEONOV (Bethesda, Maryland) |
| ABSTRACT | The disclosure provides compounds of Formula I, which may be useful as aldehyde de-hydrogenase inhibitors and the pharmaceutically acceptable salts thereof. The variables, J, R4, G, Q, and ring A are defined herein. Aldehyde dehydrogenase inhibitors of Formula I are useful for treating a variety of conditions including cancer and inflammation The disclosure includes methods for using compounds and salts of Formula I to treat colon cancer, pancreatic cancer, nasopharyngeal carcinoma, thyroid cancer, prostate cancer, ovarian cancer, head and neck squamous cell carcinoma, lung cancer, hepatocellular carcinoma, leukemia, brain tumorsbreast cancer, atherosclerosis, ischaemic heart disease, acne vulgaris, asthma, autoimmune diseases, autoinflammatory diseases, chronic prostatitis, glomerulonephritis, inflammatory bowel disease, pelvic inflammatory disease, reperfusion injury, rheumatoid arthritis, sarcoidosis, transplant rejection, vasculitis, and interstitial cystitis. The disclosure also includes pharmaceutical compositions containing a compound or salt of Formula I. |
| FILED | Monday, February 28, 2022 |
| APPL NO | 17/682654 |
| CURRENT CPC | Heterocyclic Compounds C07D 215/54 (20130101) C07D 401/04 (20130101) C07D 401/06 (20130101) C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 409/14 (20130101) C07D 413/04 (20130101) C07D 471/04 (20130101) C07D 491/107 (20130101) C07D 491/113 (20130101) Original (OR) Class C07D 495/04 (20130101) C07D 495/10 (20130101) C07D 519/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, March 16, 2023.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-applications-20230316.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page