FedInvent™ Patent Applications
Application Details for Thursday, June 01, 2023
This page was updated on Monday, June 19, 2023 at 11:21 PM GMT
Department of Health and Human Services (HHS)
| US 20230165468 | Mahadevan-Jansen et al. |
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| FUNDED BY |
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| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anita Mahadevan-Jansen (Nashville, Tennessee); Carmen C. Solorzano (Nashville, Tennessee); Giju Thomas (Nashville, Tennessee); Emmanuel A. Mannoh (Nashville, Tennessee) |
| ABSTRACT | A method for intraoperatively determining a degree of parathyroid perfusion includes identifying parathyroid tissues of a living subject using autofluorescence detection with a fiber optic probe based fluorescence detection system; administering to the living subject a contrast agent with a dose; after a period of time of the administration, detecting fluorescence in an area of the parathyroid tissues with the fiber optic probe based fluorescence detection system, where the fluorescence is emitted from the contrast agent; and obtaining a detection level and/or a detection ratio for the parathyroid tissues from the detected fluorescence so as to determine a degree of parathyroid perfusion of each parathyroid. The method is not only unaffected by ambient light, but also has no need of images of the parathyroid tissues. |
| FILED | Thursday, February 25, 2021 |
| APPL NO | 17/801862 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/06 (20130101) A61B 5/0059 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230165509 | Kuzum et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Duygu Kuzum (La Jolla, California); Xin Liu (La Jolla, California); Takaki Komiyama (La Jolla, California); Chi Ren (La Jolla, California) |
| ABSTRACT | Methods and devices for computationally constructing brain potentials across whole brain using electrocorticography signals recorded from a small region on the brain surface are disclosed. In some embodiments of the disclosed technology, a method includes obtaining a plurality of locally recorded surface potentials from a plurality of first cortical areas of a brain surface; and performing a virtual reconstruction of an average brain activity for individual cortical areas and a pixel-level cortex-wide brain activity for a plurality of cortical areas of the brain surface including the plurality of first cortical areas based on the plurality of locally recorded surface potentials. |
| FILED | Wednesday, November 30, 2022 |
| APPL NO | 18/060439 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/37 (20210101) Original (OR) Class A61B 5/384 (20210101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230165514 | Schaefer |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona) |
| INVENTOR(S) | Sydney Schaefer (Tempe, Arizona) |
| ABSTRACT | A system includes a plurality of test elements and a processor. The test elements are configured for execution of a motor task by an individual and generation of test data from trials of the motor task. The processor is configured to compute a motor test score from the test data to assess a potential neurological concern. |
| FILED | Wednesday, November 30, 2022 |
| APPL NO | 18/060059 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0531 (20130101) A61B 5/1124 (20130101) A61B 5/4088 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230165520 | SEXTON et al. |
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| APPLICANT(S) | BioVentures, LLC (Litte Rock, Arkansas); Arkansas Children's Hospital Research Institute (Little Rock, Arkansas); Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | KEVIN SEXTON (Little Rock, Arkansas); JINGXIAN WU (Little Rock, Arkansas); MORTEN JENSEN (Little Rock, Arkansas); HANNA JENSEN (Little Rock, Arkansas); MELVIN DASSINGER, III (Little Rock, Arkansas); KAYLEE HENRY (Little Rock, Arkansas); JOSEPH SANFORD (Little Rock, Arkansas); ALI AL-ALAWI (Little Rock, Arkansas); PATRICK BONASSO (Little Rock, Arkansas) |
| ABSTRACT | Disclosed herein are systems and methods for non-invasively predicting a hemodynamic state and/or an anesthetic depth of a patient, such as a pediatric patient. The method may include receiving a peripheral venous pressure (PVP) waveform from the patient, cleaning the PVP waveform, transforming the PVP waveform into the frequency domain, and automatically predicting the hemodynamic state and/or the anesthetic depth of the patient. |
| FILED | Tuesday, April 13, 2021 |
| APPL NO | 17/919474 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/318 (20210101) A61B 5/4821 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 23/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230165669 | Tomei et al. |
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| APPLICANT(S) | University of Miami (Miami, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alice A. Tomei (Miami, Florida); Aaron Stock (Miami, Florida); Michael Lupp (Miami, Florida) |
| ABSTRACT | Hydrodynamic methods for conformally coating non-uniform size cells and cell clusters with biomaterials for implantation, thus preventing immune rejection or inflammation or autoimmune destruction while preserving cell functionality, are disclosed. Further disclosed are reagents, apparatus, and methods for conformally coating cells and cell clusters with hydrogels that are biocompatible, mechanically and chemically stable and porous, with an appropriate pore cut-off size. |
| FILED | Wednesday, April 28, 2021 |
| APPL NO | 17/921888 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/022 (20130101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 35/39 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/34 (20130101) A61L 27/38 (20130101) A61L 27/3804 (20130101) A61L 2300/64 (20130101) A61L 2420/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230165699 | Lerner et al. |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of Northern Arizona University (Flagstaff, Arizona) |
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| INVENTOR(S) | Zachary F. Lerner (Flagstaff, Arizona); Grigoriy Orekhov (Flagstaff, Arizona); Leah Liebelt (Flagstaff, Arizona) |
| ABSTRACT | An assistive ankle foot orthosis is described. The AFO has a tubular vertical member arranged laterally to a user's limb. The member carries a rotational bearing and a rotational element such as a pulley. The pulley is connected to a footplate. The footplate provides joint movement assistance or resistance to the user upon rotation of the pulley. The pulley is coupled to one or more springs that provide counter-rotational resistance to pulley movement, thereby storing, and then returning, rotational force during certain foot movements. The spring can include a leaf spring arranged inside the member, the stiffness of which can be manually, automatically or dynamically adjusted by movement of the device. |
| FILED | Wednesday, January 11, 2023 |
| APPL NO | 18/095940 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 5/0127 (20130101) Original (OR) Class A61F 2005/0155 (20130101) A61F 2005/0167 (20130101) A61F 2005/0179 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230165796 | Maldonado et al. |
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| APPLICANT(S) | EndoProtech, Inc. (Louisville, Kentucky) |
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| INVENTOR(S) | Claudio Maldonado (Louisville, Kentucky); Phillip Bauer (Louisville, Kentucky) |
| ABSTRACT | The present disclosure relates to compositions comprising phospholipids, lipid vesicles, and/or liposomes, and methods of use thereof. In one aspect, the present disclosure relates to methods and compositions for delivery of, biologically active lipids to reduce microvascular dysfunction and infarct size during revascularization of the blocked artery in a mammalian subject. |
| FILED | Tuesday, January 24, 2023 |
| APPL NO | 18/101055 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/1271 (20130101) Original (OR) Class A61K 31/685 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230165812 | Woolf et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Université de Montréal (Montréal, Canada); Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Université de Montréal (Montréal, Canada); Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Clifford J. Woolf (Newton, Massachusetts); Sebastien Talbot (Montreal, Canada); Bruce P. Bean (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure provides methods of treating cancer by silencing tumor-innervating sensory neurons. The methods include treating cancer by genetic ablation of ion channels (e.g., TRPV1 or NaV1.8), local pharmacological silencing or blockade of neuropeptide release from tumor-innervating nociceptor (e.g., with QX-314 and BoNT/a), as well as the antagonism of the CGRP receptor RAMP1 (e.g., with BIBN 4096). |
| FILED | Friday, February 26, 2021 |
| APPL NO | 17/802398 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/40 (20130101) A61K 31/167 (20130101) Original (OR) Class A61K 31/4425 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230165815 | Lu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Qun Lu (Greenville, North Carolina) |
| ASSIGNEE(S) | Qun Lu (Greenville, North Carolina) |
| INVENTOR(S) | Qun Lu (Greenville, North Carolina); Yan-Hua Chen (Greenville, North Carolina); Yi Zhu (Greenville, North Carolina); Byron Aguilar (Greenville, North Carolina) |
| ABSTRACT | Methods of treating Alzheimer’s disease and other neurodegenerative and/or neurocognitive and/or neurodevelopmental diseases are described. The methods comprise the administration of compounds that modulate an activity of cell division control protein 42 (Cdc42), such as the interaction between Cdc42 and intersectin (ITSN). Exemplary modulator compounds include thioureas, disulfonamides of fused aromatic systems (e.g., benzofuran), and acyl hydrazones, among others. Some of the modulator compounds act as activators of Cdc42, while others act as inhibitors. In some cases, the modulator compound has dual functionality and the ability of the modulator compound to act as an inhibitor or activator depends on whether or not Cdc42 is already activated in a particular disease stage or biological environment by an upstream activating signal of Cdc42. |
| FILED | Monday, September 12, 2022 |
| APPL NO | 17/942657 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) Original (OR) Class A61K 31/166 (20130101) A61K 31/343 (20130101) A61K 31/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230165823 | Dewji |
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| APPLICANT(S) | Cura Therapeutics, LLC (La Jolla, California) |
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| INVENTOR(S) | Nazneen Dewji (San Diego, California) |
| ABSTRACT | Provided herein are pharmaceutical compositions, each comprising a dicarboxylic acid, for example, a compound of Formula 1, or an enantiomer, a mixture of enantiomers, a mixture of two or more diastereomers, a tautomer, a mixture of two or more tautomers, or an isotopic variant thereof; or a pharmaceutically acceptable salt, solvate, hydrate, or prodrug thereof; and a pharmaceutically acceptable excipient. Also provided herein are methods of their use for treating, preventing, or ameliorating one or more symptoms of a disorder, disease, or condition. |
| FILED | Friday, November 18, 2022 |
| APPL NO | 17/989981 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/194 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230165826 | Irie et al. |
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| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Takeshi Irie (New York, New York); Ouathek Ouerfelli (Fort Lee, New Jersey) |
| ABSTRACT | The present invention is directed to compositions for administration of camostat mesylate or nafamostat mesylate to subjects by inhalational delivery, and to methods of treatment of COVID19 by administering such compositions to subjects by inhalational delivery. |
| FILED | Thursday, March 18, 2021 |
| APPL NO | 17/912498 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0078 (20130101) A61K 31/245 (20130101) Original (OR) Class A61K 47/40 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230165841 | DHARMAKUMAR |
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| APPLICANT(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| ASSIGNEE(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| INVENTOR(S) | Rohan DHARMAKUMAR (Moorpark, California) |
| ABSTRACT | Methods of treating a subject with myocardial infarction are provided, which include selective targeting time-dependent iron products at different phases of the infarction. It is discovered that during acute phase of myocardial infarction, ferrous iron in the form of heme accumulate, often followed by infarct expansion, and during the chronic phase, ferric iron in the form of crystals are dominant Chelator agents specific for ferrous iron, heme or ferric iron are demonstrated in the protection of cardiomyocytes, reduction of infarct expansion, or improving cardiac remodeling following myocardial infarction. Also provided are methods for determining the presence of intramyocardial hemorrhage by measuring plasma level of cardiac troponin before and after re-vascularization or a reperfusion therapy, which can be used to guide therapeutic treatment or intervention procedures to control the hemorrhage and mitigate infarct expansion. |
| FILED | Friday, March 19, 2021 |
| APPL NO | 17/912227 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/165 (20130101) A61K 31/4412 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6887 (20130101) G01N 2333/4712 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230165883 | Markowitz et al. |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio); Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sanford Markowitz (Pepper Pike, Ohio); Won Jin Ho (Cleveland, Ohio); Yiyuan Yuan (Cleveland, Ohio); Mukesh Jain (Solon, Ohio); Mohamad Sabeh (Cleveland Heights, Ohio); Joseph Ready (Carrollton, Texas); Noelle Williams (Dallas, Texas) |
| ABSTRACT | A method of treating preventing, minimizing, and/or reversing congestive heart failure, cardiomyopathy, and/or reduction of cardiac ejection fraction in a subject in need thereof includes administering to the subject a therapeutically effective amount of a 15-PGDH inhibitor. |
| FILED | Tuesday, August 23, 2022 |
| APPL NO | 17/893777 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) A61K 31/496 (20130101) A61K 31/519 (20130101) A61K 31/704 (20130101) Original (OR) Class A61K 31/4355 (20130101) A61K 31/4365 (20130101) A61K 31/5377 (20130101) A61K 31/7048 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) Peptides C07K 16/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230165887 | KORINEK et al. |
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| APPLICANT(S) | Astrocyte Pharmaceuticals, Inc. (Cambridge, Massachusetts); The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | William S. KORINEK (Mystic, Connecticut); James D. LECHLEITER (San Antonio, Texas); Theodore E. LISTON (Stonington, Connecticut) |
| ABSTRACT | The present invention relates to compounds and methods of use thereof for treatment of certain disorders and conditions, for example brain injuries such as stroke or traumatic brain injuries. |
| FILED | Wednesday, September 21, 2022 |
| APPL NO | 17/934169 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/52 (20130101) A61K 31/7076 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230165889 | He et al. |
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| FUNDED BY |
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| APPLICANT(S) | Forsyth Dental Infirmary for Children (Cambridge, Massachusetts); Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xuesong He (Cypress, California); Jiahe Li (Medford, Massachusetts); Wenyuan Shi (Winchester, Massachusetts) |
| ABSTRACT | Provided herein are chemically modified transfer RNA-derived Small RNAs (tsRNAs) that target Fusobacterium nucleatum and methods of use thereof. |
| FILED | Friday, February 26, 2021 |
| APPL NO | 17/907833 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7125 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230165896 | DUNHAM et al. |
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| FUNDED BY |
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| APPLICANT(S) | Hemanext Inc. (Lexington, Massachusetts) |
| ASSIGNEE(S) | Hemanext Inc. (Lexington, Massachusetts) |
| INVENTOR(S) | Andrew DUNHAM (Tower Lakes, Illinois); Tatsuro YOSHIDA (West Newton, Massachusetts) |
| ABSTRACT | Methods for the reversal of hemorrhagic shock or hemorrhagic trauma. |
| FILED | Monday, January 09, 2023 |
| APPL NO | 18/152140 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/14 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230165955 | CURTISS |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Roy CURTISS (Gainesville, Florida) |
| ABSTRACT | Disclosed herein are unique adjuvant compositions comprising an attenuated derivative of a self-destructing bacterial pathogen that undergoes lysis in vivo. In exemplary embodiments, the bacterial pathogen is a Salmonella spp. Also disclosed are methods for enhancing an immune response using the adjuvants disclosed herein. |
| FILED | Friday, April 30, 2021 |
| APPL NO | 17/922499 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) Original (OR) Class A61K 2039/522 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230166109 | Aboud et al. |
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| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Katherine Aboud (Nashville, Tennessee); Laurie Cutting (Nashville, Tennessee) |
| ABSTRACT | Described herein are methods, systems and computer program products for individualized, non-invasive brain stimulation for enhanced learning. |
| FILED | Wednesday, November 23, 2022 |
| APPL NO | 17/993218 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36092 (20130101) Original (OR) Class A61N 1/36139 (20130101) A61N 1/37217 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230166112 | GUNDUZ et al. |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aysegul GUNDUZ (Gainesville, Florida); Jackson N. CAGLE (Gainesville, Florida); Michael S. OKUN (Gainesville, Florida); Kelly D. FOOTE (Gainesville, Florida) |
| ABSTRACT | Various examples are provided for simultaneous bilateral brain stimulation. In one example, a method includes applying a first stimulation signal at a first frequency through a feature-side implanted neural stimulator (INS) on a first side of a brain, applying a second stimulation signal at a second frequency through a non-feature-side INS on a second side of the brain, and detecting a stimulation interference signal with the non-feature-side INS. The first stimulation signal can be a pulsed signal and the second simulation signal can be a continuous signal at a low stimulation voltage, and the stimulation interference signal at an interference frequency based upon the first and second frequencies. In another example, a neural stimulation system including a feature-side neural stimulator and a non-feature-side neural stimulator implanted on first and second sides of the brain and neural stimulation circuitry coupled to the neural stimulators. |
| FILED | Monday, April 19, 2021 |
| APPL NO | 17/920102 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36171 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230166255 | Frydman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Galit H. Frydman (Boston, Massachusetts); Mehmet Toner (Charlestown, Massachusetts); Ronald G. Tompkins (Boston, Massachusetts); Pavan Bendapudi (Boston, Massachusetts) |
| ABSTRACT | Methods and devices for evaluating coagulation are described, including methods and devices for detecting an anticoagulant agent or a coagulation abnormality. In various embodiments, the methods and devices of the invention measure coagulation of a sample in response to a gradient of one or more coagulation factors. These responses can be evaluated to accurately profile coagulation impairments of the sample, including the presence of anticoagulant medication. In various embodiments, the invention provides point-of-care or bedside testing with a convenient, microfluidic device that can be used by minimally trained personnel. |
| FILED | Wednesday, January 25, 2023 |
| APPL NO | 18/159281 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/4846 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502746 (20130101) Original (OR) Class B01L 2300/165 (20130101) B01L 2400/088 (20130101) B01L 2400/0406 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/86 (20130101) G01N 33/4905 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167058 | STOCKWELL et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brent R. STOCKWELL (New York, New York); Hengrui LIU (New York, New York); Farhad FOROUHAR (New York, New York); Qian WANG (New York, New York) |
| ABSTRACT | The present disclosure provides, inter alia, compounds to modulate GPX4 activity. Also provided are pharmaceutical compositions containing same compounds. Further provided are methods for treating or ameliorating the effects of a cancer in a subject, methods of modulating GPX activity in a subject, methods of inducing ferroptosis in a cell, and methods for treating or ameliorating the effects of a cancer in a subject using the compounds or composition in combination with other therapeutic agents. |
| FILED | Monday, September 12, 2022 |
| APPL NO | 17/931341 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 209/48 (20130101) Original (OR) Class C07D 277/42 (20130101) C07D 295/16 (20130101) C07D 403/06 (20130101) C07D 409/04 (20130101) C07D 455/02 (20130101) C07D 487/04 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/2224 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167065 | Pou et al. |
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| FUNDED BY |
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| APPLICANT(S) | Oregon Health and Science University (Portland, Oregon); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Sovitj Pou (Portland, Oregon); Rolf W. Winter (Portland, Oregon); Michael K. Riscoe (Portland, Oregon); J. Stone Doggett (Portland, Oregon); Aaron Nilsen (Portland, Oregon) |
| ABSTRACT | The present invention provides synthetic methods and novel intermediates in the preparation of 3-aryl Endochin-like quinolone (ELQ) compounds. |
| FILED | Monday, May 10, 2021 |
| APPL NO | 17/998018 |
| CURRENT CPC | Heterocyclic Compounds C07D 215/233 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167071 | Serrano Brizuela et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PUERTO RICO (San Juan, Puerto Rico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Adelfa E. Serrano Brizuela (San Juan, Puerto Rico); Emilee E. Colón Lorenzo (San Juan, Puerto Rico); Jürgen Bosch (Cleveland Heights, Ohio) |
| ABSTRACT | Methods of inhibiting growth of a Plasmodium species, treating malaria, and inhibiting a glutathione S-transferase are provided. The methods include inhibiting growth of a Plasmodium species comprising contacting a Plasmodium species with a compound as disclosed herein. The methods also include treating malaria comprising administering a compound as disclosed herein to a human or animal patient, preferably a human patient, in need thereof. The methods further include inhibiting a glutathione S-transferase (GST) comprising contacting a GST with a compound as disclosed herein. Also provided are compounds for use in the disclosed methods. |
| FILED | Monday, February 10, 2020 |
| APPL NO | 17/603217 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 33/06 (20180101) Acyclic or Carbocyclic Compounds C07C 205/06 (20130101) Heterocyclic Compounds C07D 215/14 (20130101) C07D 239/26 (20130101) Original (OR) Class C07D 487/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167101 | Song et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BAYLOR COLLEGE OF MEDICINE (Houston, Texas) |
| ASSIGNEE(S) | BAYLOR COLLEGE OF MEDICINE (Houston, Texas) |
| INVENTOR(S) | Yongcheng Song (, None); Fangrui Wu (, None); Shenyou Nie (, None); Yuanda Hua (, None); Yi-Lun Lin (, None); Salma Kaochar (, None); Nicholas Mitsiades (, None) |
| ABSTRACT | Embodiments of the present disclosure pertain to compositions that include a compound that inhibits the histone acetyl transferase activity of a protein, such as p300 and/or CBP. Further embodiments of the present disclosure pertain to methods of inhibiting the histone acetyl transferase activity of a protein by exposing the protein to a composition that contains one or more of the compounds of the present disclosure. The compositions of the present disclosure may be exposed to a protein in vitro or in vivo. Additional embodiments of the present disclosure pertain to methods of treating a cancer in a subject by administering a composition of the present disclosure to the subject in order to treat the cancer. |
| FILED | Thursday, April 08, 2021 |
| APPL NO | 17/918074 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 333/20 (20130101) C07D 405/12 (20130101) C07D 405/14 (20130101) C07D 409/12 (20130101) Original (OR) Class C07D 409/14 (20130101) C07D 417/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167121 | BRUNDEN et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kurt R. BRUNDEN (Media, Pennsylvania); John Q. TROJANOWSKI (Philadelphia, Pennsylvania); Amos B. SMITH, III (Merion, Pennsylvania); Virginia M-Y LEE (Philadelphia, Pennsylvania); Carlo BALLATORE (San Diego, California); Thibault ALLE (La Jolla, California) |
| ABSTRACT | Provided are nitrile- and alkyne-substituted {1,2,4,} triazolo {1,5-A} pyrimidine compounds, compositions containing such compounds, and methods for treating a neurodegenerative disease or cancer by administration of such compounds. |
| FILED | Monday, April 12, 2021 |
| APPL NO | 17/995761 |
| CURRENT CPC | Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167154 | GILLIES et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (TAMPA, Florida); INTEZYNE TECHNOLOGIES INC. (TAMPA, Florida); ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (TUCSON, Arizona); BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (AUSTIN, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | ROBERT J. GILLIES (TAMPA, Florida); DAVID L. MORSE (TAMPA, Florida); NATALIE M. BARKEY (TAMPA, Florida); KEVIN N. SILL (TAMPA, Florida); JOSEF VAGNER (TUCSON, Arizona); NARGES K. TAFRESHI (TAMPA, Florida); JONATHAN L. SESSLER (AUSTIN, Texas); CHRISTIAN PREIHS (AUSTIN, Texas); VICTOR J. HRUBY (TUCSON, Arizona) |
| ABSTRACT | The subject invention pertains to a modified MC1R peptide ligand comprising a peptide that is a melanocortin 1 receptor (MC1R) ligand and a functionality or linker, such as a click functionality, for conjugation to a surface or agent. The modified MC1R peptide ligand can be coupled, e.g., via a click reaction with a complementary click functionality attached, to a moiety to form an MC1R-targeted agent. Drugs, contrast agents, polymers, particles, micelles, surfaces of larger structures, or other moieties can be targeted to the MC1R. The subject invention also pertains to a MC1R peptide ligand-micelle complex comprising a peptide that is a melanocortin 1 receptor ligand connected via a click reaction product to a micelle. The micelle is stable in vivo and can target melanoma tumor cells by association of the peptide ligand with the MC1R or the tumor and selectively provide a detectable and/or therapeutic agent (such as an imageable contrast agent and/or anti-cancer agent) selectively to the tumor cell. |
| FILED | Monday, January 24, 2022 |
| APPL NO | 17/582368 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/34 (20130101) A61K 47/64 (20170801) A61K 47/6907 (20170801) A61K 49/0056 (20130101) A61K 49/101 (20130101) A61K 49/1809 (20130101) Peptides C07K 5/1024 (20130101) Original (OR) Class C07K 7/08 (20130101) C07K 14/68 (20130101) C07K 14/723 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167158 | NAJJAR et al. |
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| FUNDED BY |
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| APPLICANT(S) | ICHILOV TECH LTD. (Tel Aviv, Israel); YEDA RESEARCH AND DEVELOPMENT CO. LTD. (Rehovot, Israel); BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Amer M NAJJAR (Katy, Texas); Anat GLOBERSON LEVIN (Tel Aviv, Israel); Tova WAKS (Petach Tikva, Israel); Galit HORN (Hod Hasharon, Israel) |
| ABSTRACT | The present invention discloses a fusion protein comprising a vesicular stomatitis virus envelope glycoprotein (VSVG) extracellular domain or a fragment or an analog thereof linked to a polypeptide comprising an antigen binding domain specific to cluster of differentiation 3 (CD3). The application also discloses pseudotyped viruses comprising the fusion protein and pseudotyped viruses encoding for a chimeric antigen receptor (CAR) or T-cell receptor pseudotyped in which the receptor is expressed under a CD3 promoter. Pseudotyped viruses combining these properties are encompassed as well. The application further discloses use of these pseudotyped viruses and method of producing these pseudotyped viruses. |
| FILED | Thursday, January 12, 2023 |
| APPL NO | 18/096167 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 14/70517 (20130101) C07K 16/2809 (20130101) C07K 2317/622 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2760/20023 (20130101) C12N 2760/20222 (20130101) C12N 2760/20242 (20130101) C12N 2760/20271 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167161 | Cohen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Pinchas Cohen (Los Angeles, California); Kelvin Yen (Los Angeles, California); Su-Jeong Kim (Los Angeles, California) |
| ABSTRACT | Described herein is a new mitochondrial peptide. This small peptide is capable of modulating cancer, through a variety of mechanisms including autophagy/apoptosis, reduction of tumor cell viability, inducing inflammatory response in senescent cells and conversion of macrophage cell type. Administration of the peptide, its analogs and derivatives thereof, are likely to be effective treatments for cancer therapy, including generation of synthetic analogs that further enhance or abrogate activity relative to the peptide. |
| FILED | Friday, May 14, 2021 |
| APPL NO | 17/921577 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) Peptides C07K 14/47 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167166 | Norton et al. |
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| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Larry Norton (New York, New York); Ross L Levine (New York, New York); Kelly L Bolton (St. Louis, Missouri); Ahmet Zehir (New York, New York) |
| ABSTRACT | The present invention provides a variety of methods for the identification and/or treatment of subjects that are at risk for developing life-threatening complications of SARS-CoV-2 infection and other infections. Such methods involve determining if a subject has clonal hematopoiesis. |
| FILED | Monday, April 26, 2021 |
| APPL NO | 17/920902 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) A61K 31/529 (20130101) A61K 38/1793 (20130101) A61K 38/2006 (20130101) A61K 39/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) A61P 29/00 (20180101) A61P 31/14 (20180101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 16/24 (20130101) C07K 16/241 (20130101) C07K 16/245 (20130101) C07K 16/248 (20130101) C07K 16/2866 (20130101) C07K 16/2893 (20130101) C07K 2317/24 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/70 (20130101) C12Q 1/6883 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167167 | GU et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Liangcai GU (Seattle, Washington); Zhimin HUANG (Seattle, Washington); Xiao ZHANG (Seattle, Washington) |
| ABSTRACT | Deinococcus radiodurans phytochrome (DrBphP) light form-binding antibodies are disclosed and their use in light induced dimerization systems. |
| FILED | Thursday, June 17, 2021 |
| APPL NO | 17/997582 |
| CURRENT CPC | Peptides C07K 16/1267 (20130101) Original (OR) Class C07K 2317/22 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) C07K 2317/569 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167406 | HE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Zhigang HE (Boston, Massachusetts); Jing WANG (Boston, Massachusetts); Xuelian HE (Boston, Massachusetts) |
| ABSTRACT | The invention features methods and compositions that are useful for the treatment of diseases, disorders, conditions, or injuries characterized by insufficient myelination. The methods involve administering GPR17 antagonists and microglia inhibitors or ablation agents. |
| FILED | Thursday, April 29, 2021 |
| APPL NO | 17/921802 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0622 (20130101) Original (OR) Class C12N 2501/999 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167413 | Stripp et al. |
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| FUNDED BY |
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| APPLICANT(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| ASSIGNEE(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| INVENTOR(S) | Barry R. Stripp (Malibu, California); Bindu Konda (Redondo Beach, California); Apoorva Mulay (Los Angeles, California) |
| ABSTRACT | The in vitro organoid model is a major technological breakthrough and an essential tool to study the basic biology of an organ system and for the development of various clinical applications for disease intervention. Organoids can self-renew and exhibit similarities in function as of their tissue of origin. Here, a step-by-step protocol is described to isolate region-specific progenitors from the human lung and generate 3D organoid cultures as an experimental and validation tool. |
| FILED | Friday, April 30, 2021 |
| APPL NO | 17/921174 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0689 (20130101) Original (OR) Class C12N 2501/15 (20130101) C12N 2501/727 (20130101) C12N 2509/10 (20130101) C12N 2513/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) G01N 33/5044 (20130101) G01N 33/56966 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167414 | Pohlmann et al. |
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| FUNDED BY |
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| APPLICANT(S) | Georgetown University (Washington, District of Columbia) |
| ASSIGNEE(S) | Georgetown University (Washington, District of Columbia) |
| INVENTOR(S) | Paula R. Pohlmann (Bethesda, Maryland); Seema Agarwal (Alexandria, Virginia); Richard Schlegel (Rockville, Maryland) |
| ABSTRACT | Methods of generating a population of tumor cells, such as circulating tumor cells (CTCs) isolated from fluid from a subject. The methods involve collecting a fluid sample containing the tumor cells from the subject, and culturing the tumor cells in the fluid sample in a three-dimensional cell culture, wherein the three-dimensional cell culture comprises at least one inhibitor of Rho-kinase to generate the population of CTCs. If the fluid is whole blood or contains blood, the method may also involve subjecting the fluid sample to density gradient separation to separate the tumor cells from the fluid prior to culturing. In addition, methods of identifying a candidate treatment for a subject having a condition marked by the presence of tumor cells, methods of monitoring in a subject the persistence, regression, or progression of a disease or condition marked by the presence of tumor cells, and methods of generating a cell line of tumor cells. |
| FILED | Monday, April 26, 2021 |
| APPL NO | 17/921606 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0693 (20130101) Original (OR) Class C12N 2500/02 (20130101) C12N 2500/40 (20130101) C12N 2500/99 (20130101) C12N 2501/999 (20130101) C12N 2513/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167417 | Braatz et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard Braatz (Cambridge, Massachusetts); Amos Lu (Cambridge, Massachusetts); Moo Sun Hong (Cambridge, Massachusetts) |
| ABSTRACT | Provided herein is a column-based continuous viral inactivation system, comprising one or both of a pH feedback controller to adjust feed flow rates and a minimum residence time (MRT) feedback controller to adjust feed flow rates. Methods of viral inactivation with the system are also provided. |
| FILED | Friday, April 30, 2021 |
| APPL NO | 17/997429 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 35/08 (20130101) C12M 41/26 (20130101) C12M 41/48 (20130101) C12M 47/12 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167418 | Hewitt et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Curtis Hewitt (Austin, Texas); Richard Jude Samulski (Chapel Hill, North Carolina) |
| ABSTRACT | This invention relates to modified parvovirus inverted terminal repeats (ITRs) that do not functionally interact with wild-type large Rep proteins, synthetic Rep proteins that functionally interact with the modified ITRs, and methods of using the same for delivery of nucleic acids to a cell or a subject. The modifications provide a novel Rep-ITR interaction that limits vector mobilization, increasing the safety of viral vectors. |
| FILED | Thursday, December 01, 2022 |
| APPL NO | 18/060799 |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 15/8645 (20130101) C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) C12N 2750/14162 (20130101) C12N 2750/14322 (20130101) C12N 2750/14352 (20130101) C12N 2820/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167426 | Sontheimer et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts); THE GOVERNING COUNCIL OF THE UNIVERSITYT OF TORONTO (Toronto, Canada) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Erik Sontheimer (Auburndale, Massachusetts); Alan Davidson (Toronto, Canada); Karen Maxwell (Toronto, Canada); April Pawluk (Cambridge, Massachusetts); Yan Zhang (Ann Arbor, Michigan); Jooyoung Lee (Worcester, Massachusetts); Nadia Amrani (Shrewsbury, Massachusetts) |
| ABSTRACT | The present invention is related to the field of CRISPR-Cas9 gene editing platforms. In particular, the present invention has identified Type II-C Cas9 anti-CRISPR (Acr) inhibitors that control Cas9 gene editing activity. Co-administration of such Acr inhibitors may provide an advantageous adjunct in permitting safe and practical biological therapeutics through spatial or temporal control of Cas9 activity; controlling Cas9-based gene drives in wild populations to reduce the ecological consequences of such forced inheritance schemes; and contributing to general research into various biotechnological, agricultural, and medical applications of gene editing technologies. |
| FILED | Monday, October 03, 2022 |
| APPL NO | 17/959019 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 15/907 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167427 | Fischetti et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Rockefeller University (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vincent A. Fischetti (New York, New York); Jonathan Schmitz (New York, New York); Daniel Gilmer (New York, New York); Chad Euler (New York, New York) |
| ABSTRACT | The present invention provides methods, compositions and articles of manufacture useful for the prophylactic and therapeutic amelioration and treatment of gram-positive bacteria, including Streptococcus and Staphylococcus, and related conditions. The invention provides compositions and methods incorporating and utilizing Streptococcus suis derived bacteriophage lysins, particularly PlySs2 and/or PlySs1 lytic enzymes and variants thereof, including truncations thereof. Methods for treatment of humans are provided. |
| FILED | Friday, September 03, 2021 |
| APPL NO | 17/465931 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/47 (20130101) A61K 38/50 (20130101) A61K 38/162 (20130101) A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2462 (20130101) Original (OR) Class Enzymes C12Y 302/01017 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167436 | NOYES |
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| FUNDED BY |
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| APPLICANT(S) | New York University (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Marcus NOYES (Monmouth Junction, New Jersey) |
| ABSTRACT | Provided are improved compositions and methods that are used for identifying interacting zinc fingers in a zinc finger and DNA sequence context. The compositions and methods provide a comprehensive approach that takes into account the effect of adjacent zinc fingers, in part by expanding the repertoire of F2 fingers that are varied at amino acid position 6. |
| FILED | Friday, April 30, 2021 |
| APPL NO | 17/997467 |
| CURRENT CPC | Peptides C07K 2319/81 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1086 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167452 | McNally et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois); Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Elizabeth McNally (Oak Park, Illinois); Eugene Wyatt (Chicago, Illinois) |
| ABSTRACT | The invention is directed to one or more antisense polynucleotides and their use in pharmaceutical compositions in a strategy to induce exon skipping in the γ-sarcoglycan gene in patients suffering from Limb-Girdle Muscular Dystrophy-2C (LGMD2C) or in patients at risk of such a disease. The invention also provides methods of preventing or treating muscular dystrophy, e.g., LGMD2C, by exon skipping in the gamma sarcoglycan gene using antisense polynucleotides. Accordingly, in some aspects the invention provides an isolated antisense oligonucleotide, wherein the oligonucleotide specifically hybridizes to an exon target region of a γ-sarcoglycan RNA. In another aspect, the the invention provides a method of inducing exon-skipping of a gamma sarcoglycan RNA, comprising delivering an antisense oligonucleotide or a composition to a cell. |
| FILED | Thursday, August 11, 2022 |
| APPL NO | 17/819291 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1138 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/31 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/346 (20130101) C12N 2310/351 (20130101) C12N 2310/3181 (20130101) C12N 2310/3233 (20130101) C12N 2310/3513 (20130101) C12N 2310/3521 (20130101) C12N 2320/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167453 | SOOD et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas); Consiglio Nazionale delle Ricerche (Roma, Italy) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas); Consiglio Nazionale delle Ricerche (Roma, Italy) |
| INVENTOR(S) | Anil K. SOOD (Houston, Texas); Paola AMERO (Houston, Texas); Gabriel LOPEZ-BERESTEIN (Houston, Texas); Vittorio DE FRANCISCIS (Roma, Italy) |
| ABSTRACT | Provided herein are RNA aptamers targeting CD5L. Further provided herein are methods of use thereof for the treatment of a disease or disorder, such as cancer. |
| FILED | Thursday, April 01, 2021 |
| APPL NO | 17/995343 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) Original (OR) Class C12N 2310/16 (20130101) C12N 2310/322 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167461 | Aslanidi et al. |
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| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Georgiy Aslanidi (Minneapolis, Minnesota); Karina Krotova (Minneapolis, Minnesota) |
| ABSTRACT | This disclosure describes a method that includes using dorsomorphin to increase the infectivity of adeno-associated virus (AAV). The AAV may be of any AAV serotype. In some embodiments, dorsomorphin may be used in combination with IL-6 or TNFα or both. This disclosure further describes methods for using dorsomorphin-treated cells to determine neutralizing antibody (NAb) titers. |
| FILED | Tuesday, May 18, 2021 |
| APPL NO | 17/921752 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0069 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167507 | Zhou et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Xianghong Jasmine Zhou (Los Angeles, California); Shuli Kang (Los Angeles, California); Steven Dubinett (Los Angeles, California); Wenyuan Li (Los Angeles, California); Qingjiao Li (Los Angeles, California) |
| ABSTRACT | Disclosed herein are methods and systems of utilizing sequencing reads for detecting and quantifying the presence of a tissue type or a disease type in cell-free DNA prepared from blood samples. |
| FILED | Friday, October 28, 2022 |
| APPL NO | 18/050645 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/154 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) G16B 20/20 (20190201) G16B 20/30 (20190201) G16B 25/00 (20190201) G16B 25/10 (20190201) G16B 30/00 (20190201) G16B 30/10 (20190201) G16B 30/20 (20190201) G16B 40/20 (20190201) G16B 50/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167510 | Chiu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Charles Chiu (Oakland, California) |
| ABSTRACT | Methods, compositions and kits for detection of a taxon of microorganisms in a sample are provided. |
| FILED | Thursday, April 22, 2021 |
| APPL NO | 17/920379 |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Original (OR) Class C12Q 1/6853 (20130101) C12Q 1/6895 (20130101) C12Q 2600/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230168480 | Cohen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Adam Ezra Cohen (Cambridge, Massachusetts); Shane Nichols (Cambridge, Massachusetts); Vicente Jose Parot (Cambridge, Massachusetts); Hunter Davis Ozawa (Cambridge, Massachusetts) |
| ABSTRACT | High-speed optical targeting systems and methods are described, wherein a light source, e.g., a laser, is optically coupled with a spatial light modulator. Some embodiments include a device for two-dimensional light steering. In some embodiments, the device comprises a spatial light modulator, and a laser in optical communication with the spatial light modulator. In some exemplary methods, an area is scanned withing a microscope with millisecond revisit time, such as with at least 500 individually targeted points of light. In other exemplary methods, a beam of light is directed from a laser light source into an optical system, through which the light may be focused into a line on a spatial light modulator, wherein the light can be scanned across the spatial light modulator, and directed from the spatial light modulator onto a sample. Other exemplary methods are drawn to the construction and use of the embodiments escribed herein. |
| FILED | Wednesday, April 21, 2021 |
| APPL NO | 17/920352 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/0048 (20130101) Original (OR) Class G02B 26/105 (20130101) G02B 2207/117 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20230165473 | Buller |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Army (Fort Detrick, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark J. Buller (Douglas, Massachusetts) |
| ABSTRACT | A system or a method for providing pacing guidance to an individual for a particular activity based on a physiological strain index (PSI) or an adaptive physiological strain index (aPSI). The system in at least one embodiment includes a heart rate monitor, a memory storing multiple pacing templates, a clock, an activity completion module, an output device, and a processor configured to perform multiple steps resulting in outputting pacing information to the individual. The pacing information selected in at least one embodiment is based on the individual's heart rate that provides in part a PSI or aPSI, the elapsed time for the activity, and the amount of progress through the activity. |
| FILED | Wednesday, January 25, 2023 |
| APPL NO | 18/101501 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1118 (20130101) A61B 5/02055 (20130101) Original (OR) Class A61B 5/02438 (20130101) Electric Digital Data Processing G06F 16/9017 (20190101) Computer Systems Based on Specific Computational Models G06N 5/022 (20130101) G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230165488 | Harshman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-patterson AFB, Ohio) |
| ASSIGNEE(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Sean W. Harshman (Fairborn, Ohio); Anthony V. Qualley (Washington Twp., Ohio); Nicole M. Schaeublin (Beavercreek, Ohio); Jennifer A. Martin (Beavercreek, Ohio); Claude C. Grigsby (Xenia, Ohio); Rhonda L. Pitsch (Springfield, Ohio) |
| ABSTRACT | A biomarker diagnostic system includes a sensor to collect a sweat sample from a biological subject; a processor operatively connected to the sensor, wherein the processor is configured to perform metabolic and proteomic profiling of biomarkers in the sweat sample. The metabolic and proteomic profile is compared to a predetermined profile of the biomarkers and to determine a physiological status of the biomarkers. The system further includes a feedback unit operatively coupled to the sensor and the processor and configured to output physiological performance data based on the physiological status. |
| FILED | Monday, January 09, 2023 |
| APPL NO | 18/151978 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/4866 (20130101) A61B 5/4875 (20130101) A61B 5/6802 (20130101) A61B 5/7275 (20130101) A61B 5/14517 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6848 (20130101) G01N 2560/00 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 40/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230166035 | Rosinko et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Beta Bionics, Inc. (Concord, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael J. Rosinko (Las Vegas, Nevada); Firas H. El-Khatib (Allston, Massachusetts); Edward R. Damiano (Acton, Massachusetts); David Chi-Wai Lim (Irvine, California); Edward B. Raskin (Irvine, California) |
| ABSTRACT | Automated glucose level control system that provide therapy to a subject, such as glucose control, are disclosed. The system generates dose control signals using control algorithms configured to autonomously determine doses of insulin to be infused into a subject. When the system determines that an initial dose control signal does not indicate health-appropriate therapy, the system can modify a manual therapy instruction and transmit an emergency dose control signal to the medicament pump. Disclosed systems and devices can track insulin therapy administered to the subject over a tracking period, including storing an indication of the autonomously determined doses of insulin delivered to the subject. The system can generate a backup therapy protocol with insulin therapy instructions based at least in part on the insulin therapy administered to the subject over the tracking period. |
| FILED | Friday, August 05, 2022 |
| APPL NO | 17/882469 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/14532 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/1723 (20130101) Original (OR) Class Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/17 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230166272 | Brown et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert Francis Brown (Summerland Key, Florida); Gregory M. Smith (Alexandria, Virginia); Christopher Brady (Bradenton, Florida) |
| ABSTRACT | A nozzle assembly is provided that includes two sections, the first section may be contoured and the second section may be a converging and diverging section that is downstream from the second section in the direction of gas flow. The contoured section, with a range of bend angles, allows for non-line-of-sight cold spray deposition, thereby providing location-specific control of the cold spray deposition process. |
| FILED | Friday, October 07, 2022 |
| APPL NO | 17/938681 |
| CURRENT CPC | Spraying Apparatus; Atomising Apparatus; Nozzles B05B 1/06 (20130101) Original (OR) Class B05B 15/18 (20180201) B05B 15/65 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230166873 | Cox et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Utah State University Space Dynamics Laboratory (North Logan, Utah) |
| ASSIGNEE(S) | Utah State University Space Dynamics Laboratory (North Logan, Utah) |
| INVENTOR(S) | Skylar Cox (North Logan, Utah); Justin Whitaker (Logan, Utah); John Humble (Logan, Utah); Greg Droge (Nibley, Utah) |
| ABSTRACT | For generating a points-of-interest plan, a method generates communication graph nodes for at least one satellite. The method calculates communication graph edges from the communication graph nodes, wherein the communication graph nodes and the communication graph edges comprise a communication graph. The method solves the communication graph to yield a communication plan. The method generates a points-of-interest plan from the communication plan. |
| FILED | Tuesday, September 20, 2022 |
| APPL NO | 17/933602 |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/1007 (20130101) B64G 3/00 (20130101) Original (OR) Class Electric Digital Data Processing G06F 9/4881 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167065 | Pou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Oregon Health and Science University (Portland, Oregon); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Sovitj Pou (Portland, Oregon); Rolf W. Winter (Portland, Oregon); Michael K. Riscoe (Portland, Oregon); J. Stone Doggett (Portland, Oregon); Aaron Nilsen (Portland, Oregon) |
| ABSTRACT | The present invention provides synthetic methods and novel intermediates in the preparation of 3-aryl Endochin-like quinolone (ELQ) compounds. |
| FILED | Monday, May 10, 2021 |
| APPL NO | 17/998018 |
| CURRENT CPC | Heterocyclic Compounds C07D 215/233 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167113 | COUCH et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GLAXOSMITHKLINE INTELLECTUAL PROPERTYDEVELOPMENT LIMITED (Brentford, Middlesex, United Kingdom) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ricky Wayne COUCH (Durham, North Carolina); Wenning DAI (West Chester, Pennsylvania); Senthil DAVISON (Raleigh, North Carolina); Israil PENDRAK (Collegeville, Pennsylvania); Glenn Robert WILLIAMS (Pearland, Texas) |
| ABSTRACT | Disclosed are novel crystalline forms of gepotidacin and pharmaceutical compositions containing the same. Also disclosed are processes for the preparation thereof and methods for use thereof. |
| FILED | Tuesday, April 27, 2021 |
| APPL NO | 17/997293 |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/13 (20130101) Heterocyclic Compounds C07D 471/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167510 | Chiu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Charles Chiu (Oakland, California) |
| ABSTRACT | Methods, compositions and kits for detection of a taxon of microorganisms in a sample are provided. |
| FILED | Thursday, April 22, 2021 |
| APPL NO | 17/920379 |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Original (OR) Class C12Q 1/6853 (20130101) C12Q 1/6895 (20130101) C12Q 2600/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167511 | Akbari |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Omar Akbari (La Jolla, California) |
| ABSTRACT | Provided herein is a viral RNA detection system, utilizing the RNA-targeting properties of the optimized Cas13d enzyme, CasRx, to detect SARS-CoV-2 RNA, e.g., synthetic SARS-CoV-2 RNA. The system detects novel target sequences conserved within the actively evolving genome, to provide a panel of diagnostic target sites least likely to result in false negatives due to genomic variation. Successful detection of viral RNA through both a fluorescence-based readout assay as well as a rapid paper dipstick lateral flow assay requiring no specialized laboratory equipment was shown. Low viral titers can be detected within minutes following only minutes of sample processing. |
| FILED | Wednesday, May 05, 2021 |
| APPL NO | 17/922860 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5023 (20130101) B01L 2300/0825 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 2310/20 (20170501) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/682 (20130101) C12Q 1/701 (20130101) Original (OR) Class C12Q 1/6865 (20130101) C12Q 1/6876 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167548 | Hock et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Illinois Institute of Technology (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Adam Hock (Chicago, Illinois); Michael James Foody (Chicago, Illinois) |
| ABSTRACT | The present disclosure describes a method of a thermal atomic layer deposition (ALD) process of depositing a ternary gallium oxide thin film, which includes gallium, a metal element other than gallium, and oxygen. The disclosed method starts with providing a reactive surface. Next, one or more ALD growth cycles are conducted. Each ALD growth cycle includes one or more first ALD sub-cycles and one or more second ALD sub-cycles. Herein, conducting each first ALD sub-cycles includes applying a pulse of a first metal precursor and a pulse of water sequentially, where the first metal precursor is a gallium compound. Conducting each second ALD sub-cycles includes applying a pulse of a second metal precursor and a pulse of water sequentially, where the second metal precursor includes the metal element other than gallium. |
| FILED | Tuesday, November 30, 2021 |
| APPL NO | 17/538760 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/40 (20130101) C23C 16/45527 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0228 (20130101) H01L 21/02194 (20130101) H01L 21/02205 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167620 | Arias-Thode et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | The United States of America as represented by Secretary of the Navy (San Diego, California) |
| INVENTOR(S) | Yolanda Meriah Arias-Thode (San Diego, California); Alexander Stevens-Bracy (Chula Vista, California); Bashar Dhurgham Ameen (El Cajon, California) |
| ABSTRACT | An autonomous deployment system for deploying systems and a method of deploying a seafloor device. The autonomous deployment system includes a release unit, a support frame, a plurality of mats, a hose, a plurality of weighted bands, a gas supply, a waterproof housing, and a timer. The method of deploying a seafloor device includes spooling a plurality of mats in a rolled-up position, each of said plurality of mats comprising a hose, wherein each mat is adjacent to a support frame, submerging the seafloor device in a body of water, releasing the seafloor device from a vessel via a release unit, supplying gas to each hose of the plurality of mats, unfurling each of the plurality of mats from the support frame, sinking the seafloor device to lay on the seafloor. The invention may also include a microbial fuel cell and support weights. |
| FILED | Tuesday, November 30, 2021 |
| APPL NO | 17/538888 |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 61/70 (20170101) Foundations; Excavations; Embankments; Underground or Underwater Structures E02D 29/06 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/16 (20130101) H01M 2250/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230168084 | Krovi |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RAYTHEON BBN TECHNOLOGIES, CORP. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hari Kiran Krovi (Lexington, Massachusetts) |
| ABSTRACT | Method for estimating separation distances between a plurality of image sources in a multi-point source imaging system includes: receiving a plurality of light beams, each from a respective image source and having a quantum state mode; constructing a point spread function (PSF) for light beams specific to a symmetry of the image sources; calculating a quantum Fourier transform on the quantum state mode of the plurality of light beams that achieves a quantum limit in a paraxial approximation regime to estimate separation of image sources at the quantum limit to transform the light beams; detecting the transformed light beams to generate electrical signals from respective transformed light beams; and performing signal processing on the electrical signals to estimate the separation distances between the plurality of image sources. |
| FILED | Friday, May 27, 2022 |
| APPL NO | 17/827568 |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 3/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230168198 | Yager et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Paul Yager (Seattle, Washington); Kamal Girish Shah (Seattle, Washington) |
| ABSTRACT | Systems and methods for detecting a target moiety are disclosed. A system includes a substrate holder including a porous matrix. The porous matrix includes a first detectable agent and a second detectable agent. The system includes a housing, optically coupled with the substrate holder, and shaped to optically couple with a radiation source and a radiation sensor and to optically isolate the radiation source and the radiation sensor. The system includes an excitation filter, disposed in or on the housing, configured to receive excitation electromagnetic radiation from the radiation source and to transmit a first portion of the excitation electromagnetic radiation to the porous matrix. The system also includes an emission filter, disposed in or on the housing, configured to receive emitted fluorescence electromagnetic radiation from the porous matrix and to transmit a second portion of the emitted fluorescence electromagnetic radiation, the second portion being different from the first portion. |
| FILED | Tuesday, August 10, 2021 |
| APPL NO | 17/999803 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6844 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 21/6456 (20130101) Original (OR) Class G01N 2021/6419 (20130101) G01N 2021/6421 (20130101) G01N 2021/6441 (20130101) G01N 2021/6471 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230169176 | LEE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | TAESUNG LEE (RIDGEFIELD, Connecticut); KEVIN EYKHOLT (WHITE PLAINS, New York); DOUGLAS LEE SCHALES (ARDSLEY, New York); JIYONG JANG (CHAPPAQUA, New York); IAN MICHAEL MOLLOY (WESTCHESTER, New York) |
| ABSTRACT | A processor-implemented method generates adversarial example objects. One or more processors represent an adversarial input generation process as a graph. The processor(s) explore the graph, such that a sequence of edges on the graph are explored. The processor(s) create, based on the exploring, an adversarial example object, and utilize the created adversarial example object to harden an existing process model against vulnerabilities. |
| FILED | Sunday, November 28, 2021 |
| APPL NO | 17/536059 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/577 (20130101) Original (OR) Class G06F 2221/033 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230169365 | Wu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Peggy Wu (Ellicott City, Maryland); Brett W. Israelsen (Glastonbury, Connecticut); Andrew J. Radlbeck (South Glastonbury, Connecticut); Gianna Avdic McIntire (Henderson, Nevada); Katharine G. Woodruff (Ames, Iowa) |
| ABSTRACT | A method includes obtaining multiple data items from multiple heterogeneous data sources including at least one sensor, where the multiple data items are related to operation of an autonomy. The method also includes processing the multiple data items using a machine learning model to determine a likelihood that an operator associated with the autonomy will override an action of the autonomy during the operation of the autonomy. The method further includes outputting the likelihood for review by a user. |
| FILED | Tuesday, November 30, 2021 |
| APPL NO | 17/538659 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 5/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230169673 | Krovi |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RAYTHEON BBN TECHNOLOGIES, CORP. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | RAYTHEON BBN TECHNOLOGIES, CORP. (Cambridge, Massachusetts) |
| INVENTOR(S) | Hari Kiran Krovi (Lexington, Massachusetts) |
| ABSTRACT | An optical circuit for estimating separation distances between N image sources includes an aperture for receiving N light beams and producing a point spread function specific to a symmetry of the image sources from the plurality of light beams; first optical phase shifters to shift the quantum state modes of (N-1) light beams by ɯNN; first beamsplitters, each for mixing respective pairs of quantum state modes of outputs of the first optical phase shifters for a quantum superposition of the respective pairs of the quantum state modes; second beamsplitters, each for mixing respective outputs of the first beamsplitters alternatively; second phase shifters to further shift outputs of the second beamsplitters; N detectors for converting each of the received N light beams to an analog signal; and a signal processing circuit for performing signal processing on the analog signals to estimate the separation distances. |
| FILED | Friday, May 27, 2022 |
| APPL NO | 17/827572 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/10 (20130101) Image Data Processing or Generation, in General G06T 7/70 (20170101) Original (OR) Class G06T 2207/20056 (20130101) G06T 2207/20076 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230170038 | Alacchi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aurelien Alacchi (Salt Lake City, Utah); Pierre-Emmanuel Gaillardon (Salt Lake City, Utah) |
| ABSTRACT | Electronic devices and methods for single event effect mitigation are described. The device can include a processor, a memory cell, and an integrated particle sensor. The memory cell can comprise a substrate, a deep well coupled to the substrate, and a ground-coupled well coupled to the deep well. The integrated particle sensor can be coupled between the substrate and the deep well, and the ground-coupled well and the deep well. The integrated particle sensor can be operable to detect an ionizing particle generating the single event effect. The electronic device can be a field-programmable gate array. The method can include detecting an ionizing particle generating a single event effect at a memory cell of the electronic device, switching from the memory cell to a redundant memory cell associated with the memory cell when the single event effect is detected, and reconfiguring the memory cell based on the redundant memory cell. |
| FILED | Wednesday, December 01, 2021 |
| APPL NO | 17/539923 |
| CURRENT CPC | Static Stores G11C 7/06 (20130101) G11C 7/1057 (20130101) G11C 7/1084 (20130101) G11C 29/38 (20130101) G11C 29/789 (20130101) G11C 29/4401 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230170273 | Ma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhenqiang Ma (Middleton, Wisconsin); Huilong Zhang (Madison, Wisconsin); Shaoqin Gong (Middleton, Wisconsin) |
| ABSTRACT | Flexible transistors and electronic circuits incorporating the transistors are provided. The flexible transistors promote heat dissipation from the active regions of the transistors while preserving their mechanical flexibility and high-frequency performance. The transistor designs utilize thru-substrate vias (TSVs) beneath the active regions of thin-film type transistors on thin flexible substrates. To promote rapid heat dissipation, the TSVs are coated with a material having a high thermal conductivity that transfers heat from the active region of the transistor to a large-area ground. |
| FILED | Thursday, October 06, 2022 |
| APPL NO | 17/938378 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/367 (20130101) H01L 23/3672 (20130101) Original (OR) Class H01L 23/5226 (20130101) H01L 29/778 (20130101) H01L 29/66431 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230170556 | Evans et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Aspen Aerogels, Inc. (, None) |
| ASSIGNEE(S) | Aspen Aerogels, Inc. (Northborough, Massachusetts) |
| INVENTOR(S) | Owen Richard Evans (Chelmsford, Massachusetts); Nicholas Anthony Zafiropoulos (Wayland, Massachusetts); Shannon Olga White (Bolton, Massachusetts); Wenting Dong (Marlborough, Massachusetts); Wendell E. Rhine (Belmont, Massachusetts) |
| ABSTRACT | The present invention provides a fiber-reinforced aerogel material which can be used as insulation in thermal battery applications. The fiber-reinforced aerogel material is highly durable, flexible, and has a thermal performance that exceeds the insulation materials currently used in thermal battery applications. The fiber-reinforced aerogel insulation material can be as thin as 1 mm less, and can have a thickness variation as low as 2% or less. Also provided is a method for improving the performance of a thermal battery by incorporating a reinforced aerogel material into the thermal battery. Further provided is a casting method for producing thin fiber-reinforced aerogel materials. |
| FILED | Friday, January 27, 2023 |
| APPL NO | 18/160369 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/0091 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 6/36 (20130101) H01M 6/5072 (20130101) H01M 50/116 (20210101) H01M 50/117 (20210101) H01M 50/121 (20210101) H01M 50/122 (20210101) H01M 50/124 (20210101) H01M 50/131 (20210101) H01M 50/133 (20210101) H01M 50/138 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230170611 | Chisum et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan Chisum (South Bend, Indiana); Nicolas Garcia (South Bend, Indiana) |
| ABSTRACT | An apparatus includes a plurality of antenna feed elements arranged in an array and a reflector or lens. The reflector or lens is configured to focus a first signal generated by the plurality of antenna feed elements or focus a second signal not generated by the plurality of antenna feed elements onto the plurality of antenna feed elements. The apparatus further includes a controller or processor configured to control the plurality of antenna feed elements to generate the first signal or receive the second signal. The first signal and the second signal have a nominal wavelength. The plurality of antenna feed elements are spaced from one another in the array at a distance greater than half of the nominal wavelength. |
| FILED | Thursday, April 21, 2022 |
| APPL NO | 17/725547 |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 3/2658 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230171003 | PAUDEL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Uttam PAUDEL (La Palma, California); Noel DE LA CRUZ (Compton, California); Andrew K. MOLLNER (Los Angeles, California); Alexander CHRISTIDIS (Whittier, California) |
| ABSTRACT | A reconfigurable QKD transceiver capable of transmitting and/or receiving qubits using a single optical hardware platform. This reconfigurable QKD transceiver enables various link scenarios specially for LEO-ground network, where the satellites have limited engagement time with a ground station. The reconfigurable QKD transceiver may reduce the optics SWaP by 50 percent and may allow for new mission scenarios that were otherwise not feasible with a transmitter only architecture or receiver only architecture. |
| FILED | Tuesday, November 30, 2021 |
| APPL NO | 17/537962 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/60 (20220101) Transmission H04B 10/40 (20130101) H04B 10/85 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0852 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230171013 | Bedrosian |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MITRE Corporation (McLean, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | P. Stephan Bedrosian (McLean, Virginia) |
| ABSTRACT | A range is determined between two unsynchronized communications terminals in which a first terminal transmits a range request to a second terminal. The first terminal stores a first timestamp in memory corresponding to a time at which the range request message was transmitted. A range response is later received by the first terminal from the second terminal. The range response includes a residence time that characterizes an amount of time the second terminal required to send the range response after receiving the range request. The first terminal later stores a second timestamp in memory corresponding to a time at which the range response was received. Based on the second timestamp minus the first timestamp and the residence time, a roundtrip time for the range request is calculated. This roundtrip time can be used to calculate a distance between the first terminal and the second terminal based on the roundtrip time. |
| FILED | Tuesday, November 30, 2021 |
| APPL NO | 17/538146 |
| CURRENT CPC | Multiplex Communication H04J 3/0661 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 43/0864 (20130101) Wireless Communication Networks H04W 56/0065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230171142 | KASSAS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Zak KASSAS (Irvine, California); Kimia SHAMAEI (Irvine, California) |
| ABSTRACT | Processes and device configurations are provided for extracting observables from communications signals. Methods include performing a frequency extraction on received communication signals to determine a carrier frequency, acquiring an estimation of channel frequency response and a frame start time. Signal tracking is performed to update frame start time of a signal physical broadcast channel block structure (SS/PBCH) in the communication signal, and at least one observable is extracted from the communications signal based on the updated estimate of frame start time. Characteristics of communications signal, such as frame structure including a synchronization signal physical broadcast channel block structure (SS/PBCH) may be used to opportunistically extract time of arrival (TOA) from communications signals. Symbols and subcarriers of new radio signals may be used to extract reference signals, and to determine one or more navigation observables based on communication signal. |
| FILED | Tuesday, May 18, 2021 |
| APPL NO | 17/926000 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 27/265 (20130101) Original (OR) Class H04L 27/2662 (20130101) Wireless Communication Networks H04W 56/001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230171147 | Farritor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shane Farritor (Lincoln, Nebraska); Tyler Wortman (Grand Island, Nebraska); Kyle Strabala (Pittsburgh, Pennsylvania); Ryan McCormick (Valencia, California); Amy Lehman (York, Nebraska); Dmitry Oleynikov (Omaha, Nebraska); Eric Markvicka (Lincoln, Nebraska) |
| ABSTRACT | Various medical devices and related systems, including robotic and/or in vivo medical devices, and various robotic surgical devices for in vivo medical procedures. Included herein, for example, is a robotic surgical system having a support beam positionable through an incision, and a robotic device having a device body, first and second rotating shoulder components coupled to the device body, and first and second robotic arms coupled to the first and second shoulder components, respectively. |
| FILED | Tuesday, January 24, 2023 |
| APPL NO | 18/158810 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/30 (20160201) A61B 90/30 (20160201) A61B 90/361 (20160201) A61B 2034/302 (20160201) Manipulators; Chambers Provided With Manipulation Devices B25J 9/06 (20130101) B25J 9/0087 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 2219/40418 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 41/0631 (20130101) Original (OR) Class H04L 43/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20230165515 | Arnold et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | KNOW BIOLOGICAL, INC. (Milton, Georgia); National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gary Stephen Arnold (Cumming, Georgia); Matthew Wallace Moorman (Albuquerque, New Mexico); Joshua Jonathan Whiting (Albuquerque, New Mexico) |
| ABSTRACT | A wearable health monitoring device includes a band configured to attach the wearable health monitoring device to a user's body; a VOC detection device configured to collect and analyze volatile organic compounds given off from the user's skin to identify specific health-indicative volatile organic compounds indicative of a health condition; and a biomarker sensor configured to detect a biomarker of the user. |
| FILED | Tuesday, December 20, 2022 |
| APPL NO | 18/069047 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/443 (20130101) A61B 5/4094 (20130101) Original (OR) Class A61B 5/6831 (20130101) A61B 5/6833 (20130101) A61B 5/14546 (20130101) A61B 10/00 (20130101) A61B 2010/0083 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/00 (20130101) G01N 30/20 (20130101) G01N 30/60 (20130101) G01N 30/64 (20130101) G01N 30/80 (20130101) G01N 2030/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230165934 | ZISCHKA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HELMHOLTZ ZENTRUM MÜNCHEN - DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHET UND UMWELT (GMBH) (NEUHERBERG, Germany); THE REGENTS OF THE UNIVERITY OF MICHIGAN (ANN ARBOR, Michigan); IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (AMES, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hans ZISCHKA (Munich, Germany); Josef LICHTMANNEGGER (Neuching, Germany); Alan Angelo DISPIRITO (Ames, Iowa); Jeremy David SEMRAU (Ann Arbor, Michigan) |
| ABSTRACT | The present invention relates to the field of (bio-)medicine, and more particularly to the treatment of copper-related diseases. Novel means and methods for depleting (excess) copper from organs and/or the circulation are provided. Agents with a high copper binding affinity and stabilized forms thereof are provided, as well as a novel treatment regimen. The means and methods of the present invention are particularly useful for treatment of Wilson Disease, but also for treatment of other conditions. |
| FILED | Wednesday, January 25, 2023 |
| APPL NO | 18/101233 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/164 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/16 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230166246 | Delferro et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Massimiliano Delferro (Chicago, Illinois); Magali S. Ferrandon (Steger, Illinois); Kenneth R. Poeppelmeier (Evanston, Illinois); Aaron D. Sadow (Ames, Iowa); Susannah Scott (Goleta, California); Anne M. LaPointe (Lemont, Illinois); Geoffrey Coates (Lemont, Illinois) |
| ABSTRACT | A method of upcycling polymers to useful hydrocarbon materials. A catalyst with nanoparticles on a substrate selectively docks and cleaves longer hydrocarbon chains over shorter hydrocarbon chains. The catalyst includes metal nanoparticles in an order array on a substrate. |
| FILED | Friday, January 13, 2023 |
| APPL NO | 18/096758 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/42 (20130101) B01J 35/0013 (20130101) Original (OR) Class B01J 35/023 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/50 (20130101) C08F 10/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230166253 | Torres |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sabrina Marie Wells Torres (Lee's Summit, Missouri) |
| ABSTRACT | A microfluidic device having hydrophobic and hydrophilic regions and a method of manufacture thereof are provided. The microfluidic device may include one or more channels formed using a short-pulse laser that are configured for separation or mixing of fluids. The microfluidic device may further include hydrophilic or hydrophobic surfaces configured to aid in the separation or mixture of fluids. The short-pulse laser may be a femtosecond laser. |
| FILED | Wednesday, December 01, 2021 |
| APPL NO | 17/539746 |
| CURRENT CPC | Separation B01D 17/045 (20130101) Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 33/30 (20220101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 3/502746 (20130101) Original (OR) Class B01L 2200/12 (20130101) B01L 2300/12 (20130101) B01L 2300/161 (20130101) B01L 2400/088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230166265 | BEER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | N. Reginald BEER (Pleasanton, California); Gary JOHNSON (Livermore, California) |
| ABSTRACT | Techniques, systems, and devices are disclosed for implementing a portable lab system for PCR testing. An example method for operating an integrated thermal cycling system includes depositing samples into the integrated thermal cycling system that includes a thermal cycling device and an electronic interface. The thermal cycling device includes multiple wells to receive the samples to be thermally cycled, a thermoelectric cooling (TEC) element connected to the multiple wells, a substrate on which the TEC element is positioned, and a controller coupled to the TEC element. The multiple wells are positioned within the substrate that includes a thermally conductive ground positioned between adjacent wells. Supplying power to the integrated thermal cycling system, via the electronic interface, allows the multiple wells to exchange heat with the substrate and for each well to operate independently from other wells. |
| FILED | Tuesday, August 02, 2022 |
| APPL NO | 17/816886 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 7/525 (20130101) Original (OR) Class B01L 2300/1805 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Electric solid-state devices not otherwise provided for H10N 10/13 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230166448 | Pino et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing & Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing & Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Ruben A. Pino (Kansas City, Missouri); Ryan J. Eickbush (Grandview, Missouri) |
| ABSTRACT | A nozzle holder assembly for a three-dimensional printer comprises a mount, a printer nozzle, and a locking mechanism. The mount is operable to be secured to the three-dimensional printer. The printer nozzle shaft is movably coupled to the mount along a predetermined length. The locking mechanism is configured to fix the printer nozzle shaft relative to the mount at any position along the predetermined length. |
| FILED | Tuesday, November 30, 2021 |
| APPL NO | 17/538231 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/25 (20170801) B29C 64/209 (20170801) Original (OR) Class B29C 64/386 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167025 | FERRARO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida); RJ LEE GROUP, INC. (Monroeville, Pennsylvania); ELECTRIC POWER RESEARCH INSTITUTE, INC. (Palo Alto, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher C. FERRARO (Gainesville, Florida); Jerry M. PARIS (Gainesville, Florida); James E. BACIAK (Gainesville, Florida); Kyle A. RIDING (Gainesville, Florida); Ashish D. PATEL (Gainesville, Florida); David B. SCOTT (Charlotte, North Carolina); Eric R. GIANNINI (La Crosse, Wisconsin) |
| ABSTRACT | Aspects of the present disclosure provide for cement, cement paste, cementitious paste, cementitious mortar, and concrete, methods of making cement, cement paste, cementitious paste, cementitious mortar, and concrete, structures incorporating the concrete, and the like, where the cement, cement paste, cementitious paste, cementitious mortar, and the concrete include elemental boron and/or one or more boron compounds (e.g., boron-doped cement, cement paste, cementitious paste, cementitious mortar, and concrete). The boron and/or a boron compound can be homogeneously distributed throughout the cement, cement paste, cementitious paste, cementitious mortar and/or concrete. |
| FILED | Tuesday, April 20, 2021 |
| APPL NO | 17/919692 |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 20/1055 (20130101) C04B 22/0013 (20130101) Original (OR) Class C04B 2111/00862 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167225 | Mayfield et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California); Algenesis Corporation (Cardiff, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen Mayfield (La Jolla, California); Robert Pomeroy (La Jolla, California); Michael Burkart (La Jolla, California); Natasha Gunawan (La Jolla, California); Ariel Schreiman (La Jolla, California); Marissa Tessman (Cardiff, California); Nitin Neelakantan (Cardiff, California); Ryan Simkovsky (La Jolla, California) |
| ABSTRACT | Disclosed herein are bio-based polymers, methods to prepare the same, bio-based polymer products, methods to degrade the same, and methods to recycle the same. |
| FILED | Monday, April 26, 2021 |
| APPL NO | 17/921588 |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/4238 (20130101) Original (OR) Class C08G 2101/00 (20130101) C08G 2230/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 11/105 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167355 | ROSALES et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bryan Anthony ROSALES (Boulder, Colorado); Lance Michael WHEELER (Golden, Colorado) |
| ABSTRACT | The present disclosure relates to a composition that includes a first phase that includes a perovskite and a second phase that includes a salt, a polymer, and a switching molecule, where the first phase and the second phase are in physical contact, and the composition is capable of reversibly switching between a substantially opaque state and a substantially transparent state. |
| FILED | Thursday, December 01, 2022 |
| APPL NO | 18/073505 |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/19 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 9/02 (20130101) Original (OR) Class C09K 2211/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230168231 | Small et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Leo J. Small (Albuquerque, New Mexico); Stephen J. Percival (Albuquerque, New Mexico); Tina M. Nenoff (Albuquerque, New Mexico); Mara E. Schindelholz (Columbus, Ohio) |
| ABSTRACT | The invention is directed to a chemically robust, highly-selective, low power sensor that can be used for the direct electrical detection of mixed gases. In particular, metal-organic frameworks (MOFs) offer exceptional chemical and structural tunability as mixed-gas capture materials. As an example of the invention, the influence of interfering gases on trace NO2 detection in a simulated flue gas stream was investigated. The unique interaction of NO2 with the MOF's metal center leads to orders of magnitude decrease in MOF resistance. More broadly, the coadsorption of specific gases (e.g., H2O, SO2) can be beneficial to the electrical detection of the target gas (e.g., NO2), and careful electrical measurements can discern their presence independent of the target gas. |
| FILED | Tuesday, January 31, 2023 |
| APPL NO | 18/103617 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/12 (20130101) G01N 27/227 (20130101) G01N 33/0027 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230168390 | Burghard et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Brion J. Burghard (West Richland, Washington); William G. Bennett (West Richland, Washington); Kurt L. Silvers (Pasco, Washington); Anton S. Sinkov (Richland, Washington); Erik S. Simunds (Kennewick, Washington); Andrei B. Valsan (Richland, Washington); Sean D. McGaughey (West Richland, Washington) |
| ABSTRACT | Radiation monitoring devices and associated methods are described. According to one aspect, a radiation monitoring device includes a housing configured to pass radiation emitted from a radiological source located in proximity to the radiation monitoring device, a radiation detector configured to receive the radiation emitted from the radiological source and to generate information regarding the radiation, and communications circuitry configured to communicate the information regarding the radiation in a plurality of communications at a plurality of different moments in time externally of the radiation monitoring device |
| FILED | Monday, November 29, 2021 |
| APPL NO | 17/537205 |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/17 (20130101) Original (OR) Class Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 5/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230168557 | GILLASPIE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SAGE ELECTROCHRMICS, INC. (Faribault, Minnesota); ALLIANCE FOR SUSTAINABLE ENERGY, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dane T. GILLASPIE (Golden, Colorado); Douglas G. WEIR (Northfield, Minnesota) |
| ABSTRACT | An electrochromic device comprising a counter electrode layer comprised of lithium metal oxide which provides a high transmission in the fully intercalated state and which is capable of long-term stability, is disclosed. Methods of making an electrochromic device comprising such a counter electrode are also disclosed. |
| FILED | Monday, October 31, 2022 |
| APPL NO | 18/051309 |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 9/00 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/155 (20130101) G02F 1/1524 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230168646 | Lyle et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Joshua A. Lyle (Plainfield, Illinois); Nathaniel Evans (Orland Hills, Illinois); Steven Day (Lemont, Illinois) |
| ABSTRACT | At least one embodiments relates to a system for testing industrial processes and industrial control systems including a physical environment, including at least one industrial control system hardware and at least one physical model, and a computer system comprising a processor and a memory, wherein the processor is set up to perform operations, embodied in instructions on computer-readable medium. The operations include virtually linking the physical environment and a virtual environment, inputting at least one document comprising supporting software and a scenario instruction set, generating a scenario according to the scenario instruction set, simulating the scenario, and displaying simulation results of the simulated scenario. |
| FILED | Monday, November 29, 2021 |
| APPL NO | 17/537093 |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/04 (20130101) G05B 17/02 (20130101) Original (OR) Class G05B 19/048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230169248 | Miryala et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Fermi Research Alliance, LLC (Batavia, Illinois) |
| ASSIGNEE(S) | Fermi Research Alliance, LLC (Batavia, Illinois) |
| INVENTOR(S) | Sandeep Miryala (Sound Beach, New York); James Richard Hoff (Wheaton, Illinois); Grzegorz W. Deptuch (Great Neck, New York) |
| ABSTRACT | A soft error-mitigating semiconductor design system and associated methods that tailor circuit design steps to mitigate corruption of data in storage elements (e.g., flip flops) due to Single Events Effects (SEEs). Required storage elements are automatically mapped to triplicated redundant nodes controlled by a voting element that enforces majority-voting logic for fault-free output (i.e., Triple Modular Redundancy (TMR)). Storage elements are also optimally positioned for placement in keeping with SEE-tolerant spacing constraints. Additionally, clock delay insertion (employing either a single global clock or clock triplication) in the TMR specification may introduce useful skew that protects against glitch propagation through the designed device. The resultant layout generated from the TMR configuration may relax constraints imposed on register transfer level (RTL) engineers to make rad-hard designs. as automation introduces TMR storage registers, memory element spacing, and clock delay/triplication with minimal designer input. |
| FILED | Tuesday, January 31, 2023 |
| APPL NO | 18/103970 |
| CURRENT CPC | Electric Digital Data Processing G06F 30/327 (20200101) Original (OR) Class G06F 30/392 (20200101) G06F 30/396 (20200101) G06F 2119/02 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230169381 | WANG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | IonQ, Inc. (College Park, Maryland); University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Qingfeng WANG (College Park, Maryland); Ming LI (College Park, Maryland); Yunseong NAM (College Park, Maryland) |
| ABSTRACT | Aspects of the present disclosure describe a method including predicting a first set of ansatz terms and a first plurality of amplitudes associated with the first set of ansatz terms; minimizing energy of the system based on the first set of ansatz terms and the first plurality of amplitudes; computing perturbative corrections using one or more ansatz wavefunctions; determining whether energy of the system converges; and predicting, in response to determining that the energy of the system does not converge, a second set of ansatz terms and a second plurality of amplitudes associated with the second set of ansatz terms. |
| FILED | Friday, December 30, 2022 |
| APPL NO | 18/148670 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/5094 (20130101) G06F 30/20 (20200101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
20230170101 — COMPACT PASSIVE DECAY HEAT REMOVAL SYSTEM FOR TRANSPORTABLE MICRO-REACTOR APPLICATIONS
| US 20230170101 | SWARTZ et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania) |
| ASSIGNEE(S) | Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania) |
| INVENTOR(S) | Matthew M. SWARTZ (Claridge, Pennsylvania); Anthony G. TRUPIANO (Pittsburgh, Pennsylvania); Jurie J. VAN WYK (Mars, Pennsylvania) |
| ABSTRACT | A container for transporting a reactor is disclosed. The container includes a loop thermosiphon including a chamber, a heat exchanger fluidically coupled to the chamber, and an actuator including an unactuated state and an actuated state. The actuator is configured to automatically transition to the actuated state. The transition is based on an event occurring within the reactor. A working medium is configured to remove heat from the reactor in the actuated state. |
| FILED | Monday, April 19, 2021 |
| APPL NO | 17/997629 |
| CURRENT CPC | Nuclear Reactors G21C 1/326 (20130101) Original (OR) Class G21C 13/024 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230170102 | ALESHIN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania) |
| ASSIGNEE(S) | Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania) |
| INVENTOR(S) | Yuriy ALESHIN (Cayce, South Carolina); Stuart KELLNER (Pittsburgh, Pennsylvania) |
| ABSTRACT | A nuclear reactor core mechanical support bracket is disclosed. The support bracket includes a housing, a spring disposed internally within the housing, a shaft slidingly disposed within the housing, a shaft travel pin, and a flange. The shaft is configured to engage the spring to compress and decompress the spring as the shaft travels in and out of the housing. The shaft travel pin controls the travel of the shaft. The flange is configured to mount the nuclear reactor core mechanical support bracket to a canister of a nuclear reactor. The shaft includes an inset configured to interface with a nuclear reactor core component. |
| FILED | Tuesday, January 17, 2023 |
| APPL NO | 18/155193 |
| CURRENT CPC | Nuclear Reactors G21C 5/08 (20130101) G21C 5/10 (20130101) Original (OR) Class G21C 11/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230170152 | Dighe |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRIAD National Security, LLC. (Los Alamos, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kalpak Arvind Dighe (Los Alamos, New Mexico) |
| ABSTRACT | A device includes a first capacitive energy module and a second capacitive energy module. The first capacitive energy module comprises a first tray that is configured to house a first plurality of capacitive energy components, a first electrode, and a second electrode. The second capacitive energy module comprises a second tray that is configured to house a second plurality of capacitive energy components, a third electrode, and a fourth electrode. The first capacitive energy module is connected to the second capacitive energy module via a plug connector that makes a solid connection. |
| FILED | Thursday, December 01, 2022 |
| APPL NO | 18/073512 |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 4/224 (20130101) H01G 4/385 (20130101) Original (OR) Class X-ray Technique H05G 1/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230170473 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Hsien-Han Wang (Downers Grove, Illinois); Ritesh Jagatramka (Chicago, Illinois); Samuel Plunkett (Chicago, Illinois); Larry A. Curtiss (Downers Grove, Illinois); Khalil Amine (Oak Brook, Illinois) |
| ABSTRACT | An electrochemical device includes a lithium anode having a red poly(benzonitrile) coating covering at least a portion of the anode; a separator and an air cathode comprising reduced graphene oxide over gas diffusion layer; and an electrolyte comprising an ether solvent, benzonitrile, and a lithium salt. |
| FILED | Thursday, January 26, 2023 |
| APPL NO | 18/101663 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/62 (20130101) H01M 4/134 (20130101) H01M 4/366 (20130101) Original (OR) Class H01M 4/382 (20130101) H01M 4/885 (20130101) H01M 4/926 (20130101) H01M 4/8882 (20130101) H01M 12/08 (20130101) H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230170494 | McLarty et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington State University (Pullman, Washington) |
| ASSIGNEE(S) | Washington State University (Pullman, Washington) |
| INVENTOR(S) | Dustin McLarty (Pullman, Washington); John Drazin (Pullman, Washington) |
| ABSTRACT | Modular pressurized hotbox for use and substitution in a variety of pressurized electrochemical applications to include reversible solid oxide electrolyzer and fuel cells, energy storage systems, renewable fuel production, solid-state hydrogen pumping and liquefaction, and oxygen transport membranes. This is enabled by mixed electronic and ionic conducting compositions of vanadia-yttria and vanadia-calcia stabilized zirconia and a dry powder method of manufacture for ceramic core stacks. |
| FILED | Monday, January 23, 2023 |
| APPL NO | 18/100282 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/8657 (20130101) H01M 4/8885 (20130101) H01M 4/9025 (20130101) H01M 4/9066 (20130101) Original (OR) Class H01M 8/1213 (20130101) H01M 8/1253 (20130101) H01M 8/2425 (20130101) H01M 8/04089 (20130101) H01M 2008/1293 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230170901 | Lu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Fei Lu (Wynnewood, Pennsylvania); Hua Zhang (Philadelphia, Pennsylvania); Reza Kheirollahi (Philadelphia, Pennsylvania) |
| ABSTRACT | A thyristor-based dc solid state circuit breaker (SSCB) named Y-type includes a new complementary commutation circuit including a capacitor-capacitor pair, which features three advantages. First, a fast commutation is achieved using a countercurrent pulse injection by the capacitor-capacitor pair structure. Second, metal-oxide varistors (MOVs) are disconnected from the power line when SSCB is OFF, which solves the reliability issue due to the MOV degradation and enhances the voltage utilization rate of the main switch. Third, benefiting from the capacitor-capacitor pair structure, reliable reclosing and rebreaking are obtained for practical applications. |
| FILED | Wednesday, November 23, 2022 |
| APPL NO | 18/058440 |
| CURRENT CPC | Pulse Technique H03K 17/73 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20230165509 | Kuzum et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Duygu Kuzum (La Jolla, California); Xin Liu (La Jolla, California); Takaki Komiyama (La Jolla, California); Chi Ren (La Jolla, California) |
| ABSTRACT | Methods and devices for computationally constructing brain potentials across whole brain using electrocorticography signals recorded from a small region on the brain surface are disclosed. In some embodiments of the disclosed technology, a method includes obtaining a plurality of locally recorded surface potentials from a plurality of first cortical areas of a brain surface; and performing a virtual reconstruction of an average brain activity for individual cortical areas and a pixel-level cortex-wide brain activity for a plurality of cortical areas of the brain surface including the plurality of first cortical areas based on the plurality of locally recorded surface potentials. |
| FILED | Wednesday, November 30, 2022 |
| APPL NO | 18/060439 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/37 (20210101) Original (OR) Class A61B 5/384 (20210101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230165520 | SEXTON et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BioVentures, LLC (Litte Rock, Arkansas); Arkansas Children's Hospital Research Institute (Little Rock, Arkansas); Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | KEVIN SEXTON (Little Rock, Arkansas); JINGXIAN WU (Little Rock, Arkansas); MORTEN JENSEN (Little Rock, Arkansas); HANNA JENSEN (Little Rock, Arkansas); MELVIN DASSINGER, III (Little Rock, Arkansas); KAYLEE HENRY (Little Rock, Arkansas); JOSEPH SANFORD (Little Rock, Arkansas); ALI AL-ALAWI (Little Rock, Arkansas); PATRICK BONASSO (Little Rock, Arkansas) |
| ABSTRACT | Disclosed herein are systems and methods for non-invasively predicting a hemodynamic state and/or an anesthetic depth of a patient, such as a pediatric patient. The method may include receiving a peripheral venous pressure (PVP) waveform from the patient, cleaning the PVP waveform, transforming the PVP waveform into the frequency domain, and automatically predicting the hemodynamic state and/or the anesthetic depth of the patient. |
| FILED | Tuesday, April 13, 2021 |
| APPL NO | 17/919474 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/318 (20210101) A61B 5/4821 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 23/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230165830 | Baker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); THE UAB RESEARCH FOUNDATION (Birmingham, Alabama) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bill J. Baker (Temple Terrace, Florida); Lindsey N. Shaw (Tampa, Florida); Andrew Jason Shilling (Tampa, Florida); Alexandre Jean Bory (Yvonand, Switzerland); Jessie Allen (Adams) (Tampa, Florida); Charles Dunkle Amsler, JR. (Pelham, Alabama); James Bruce McClintock (Birmingham, Alabama) |
| ABSTRACT | Described herein are Dendrilla membranosa compounds and derivatives thereof. Also described herein are formulations that can contain an amount of one or more Dendrilla membranosa compounds or derivatives thereof and a carrier. Also described herein are methods of administering one or more Dendrilla membranosa compound and/or derivative thereof or a formulation thereof to a subject in need thereof. |
| FILED | Monday, January 09, 2023 |
| APPL NO | 18/152098 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/192 (20130101) A61K 31/343 (20130101) Original (OR) Class A61K 31/352 (20130101) A61K 2236/39 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230166012 | BENIASH et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (PITTSBURGH, Pennsylvania) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (PITTSBURGH, Pennsylvania) |
| INVENTOR(S) | ELIA BENIASH (PITTSBURGH, Pennsylvania); AVINASH PATIL (PITTSBURGH, Pennsylvania) |
| ABSTRACT | The invention relates to self-assembled organosilane- and small molecule drug-containing coatings for resorbable medical implant devices. The coatings can be prepared from precursor compositions containing an organosilane and a small molecule drug, and can be applied to substrates. Prior to applying the coatings, the surfaces of the substrates can be pretreated. The coatings can be functionalized with a binding compound that is coupled with an active component. The coatings can be applied using various techniques and apparatus, more particularly, by a deep-coating process conducted at ambient conditions. |
| FILED | Friday, January 13, 2023 |
| APPL NO | 18/096736 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/65 (20130101) A61K 31/352 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 29/16 (20130101) A61L 29/148 (20130101) A61L 31/16 (20130101) Original (OR) Class A61L 31/148 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230166965 | KIM et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Seok KIM (Pohang-si, South Korea); Jun Kyu PARK (Portland, Oregon) |
| ABSTRACT | A method of liquid-mediated pattern transfer includes providing a substrate comprising (a) a semiconductor film adhered to the substrate and (b) a first patterned layer on the semiconductor film. The substrate is submerged in a delamination liquid, whereby the semiconductor film is delaminated from the substrate while the first patterned layer remains on the semiconductor film. A patterned semiconductor membrane ready for transfer is thus obtained. The patterned semiconductor membrane is transferred to a target substrate in a transfer liquid, and then the transfer liquid is removed (e.g., evaporated). The patterned semiconductor membrane adheres to the target substrate as the transfer liquid is removed. |
| FILED | Monday, November 21, 2022 |
| APPL NO | 17/990902 |
| CURRENT CPC | Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00158 (20130101) Original (OR) Class B81C 2201/0133 (20130101) B81C 2201/0194 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167211 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Junpeng Wang (Peninsula, Ohio); Devavrate Sathe (Akron, Ohio); Junfeng Zhou (Shenzhen, China PRC); Hanlin Chen (Stow, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Junpeng Wang (Peninsula, Ohio); Devavrate Sathe (Akron, Ohio); Junfeng Zhou (Shenzhen, China PRC); Hanlin Chen (Stow, Ohio) |
| ABSTRACT | A monomer capable forming a polymer through ring-opening metathesis polymerization and capable of depolymerization thereafter through ring-closing metathesis, wherein the monomer comprises a cycloalkene having a fused ring attached thereto to form a cycloalkene-fused ring monomer, wherein the fused ring decreases the ring strain energy of the cycloalkene to a lower ring strain energy state of 5.3 kcal/mol or lower as compared to the same cycloalkene without the fused ring having a ring strain energy above 5.3 kcal/mol and wherein the cycloalkene-fused ring monomer is capable of isomerization into a higher ring strain energy state before polymerization and method of synthesizing the monomer. The monomer is further capable of forming chemically recyclable to monomers block copolymers. |
| FILED | Friday, September 30, 2022 |
| APPL NO | 17/937144 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 43/162 (20130101) C07C 69/753 (20130101) Heterocyclic Compounds C07D 209/94 (20130101) C07D 307/93 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 132/08 (20130101) Original (OR) Class C08F 299/022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167303 | Flood et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (Indianapolis, Indiana); UNIVERSITY OF COPENHAGEN (Copenhagen, Denmark) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Amar H. Flood (Bloomington, Indiana); Bo Wegge Laursen (Copenhagen, Denmark) |
| ABSTRACT | The present disclosure concerns the design, formulations, preparations and optical properties of compounds of Formulas (I) and (VI): (charged dyem+)x·(counterionn−)y·(counterion receptor)z (I) and (charged dyem−)x·(counterionn+)y·(counterion receptor)z (VI). The charged dyem+ is a cationic dye, counterionn− is an anion, and counterion receptor is a binding ligand for the counterionn−, wherein m, n, x and y are integers greater than or equal to 1, and products of x·n and m·y are identical for formula (I). The charged dyem− is a anionic dye, counterionn+ is a cation, and counterion receptor is a binding ligand for the counterionn+, wherein m, n, x and y are integers greater than or equal to 1, and products of x·n and m·y are identical for formula (VI). |
| FILED | Saturday, September 10, 2022 |
| APPL NO | 17/942127 |
| CURRENT CPC | Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 11/24 (20130101) Original (OR) Class C09B 19/00 (20130101) C09B 23/0075 (20130101) C09B 23/0091 (20130101) C09B 57/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/02 (20130101) C09K 11/06 (20130101) C09K 2211/1007 (20130101) C09K 2211/1018 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) G01N 2001/302 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167375 | Kraus et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | George A. Kraus (Ames, Iowa); Kyle Podolak (Ames, Iowa); Derek Lee White (Lakewood, Colorado); Sriram Sundararajan (Ames, Iowa) |
| ABSTRACT | The present invention is toward a base oil or lubricant additives, methods of using the same, lubricant compositions including the same, and methods of forming the lubricant compositions. A base oil or lubricant additive has Structure I or Structure II as described herein. |
| FILED | Wednesday, November 23, 2022 |
| APPL NO | 18/058635 |
| CURRENT CPC | Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition C10M 129/70 (20130101) Original (OR) Class C10M 169/04 (20130101) Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions C10N 2030/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167403 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); PIONEER HI-BRED INTERNATIONAL, INC. (Johnston, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Abraham P. Lee (Irvine, California); Gisela Lin (Irvine, California); Yue Yun (Johnston, Iowa); Elizabeth Chatt (Johnston, Iowa); Marzieh Ataei (Irvine, California); Jui-Yi Chen (Irvine, California) |
| ABSTRACT | Microfluidic devices and methods for co-encapsulation of a cell and a controlled release particle in one droplet are escribed herein. The devices and methods utilize laminar flow, high shear liquid-liquid interfaces, hydrodynamic vortices, and/or acoustic focusing to increase co-encapsulation efficiency. The precise variation of the droplets microenvironment is enabled by the controlled release particle co-encapsulated with the single cell in each droplet. This capability, coupled with established detection methods, provides an important tool for precise, single cell analysis. |
| FILED | Tuesday, May 04, 2021 |
| APPL NO | 17/922908 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/04 (20130101) C12N 5/0012 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230168075 | Liang |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rongguang Liang (Tucson, Arizona) |
| ABSTRACT | Systems, devices and methods for measuring surface roughness and surface shape of an optical element using a dual-mode interferometer are disclosed. The devices implement optical filters, with a compact form, that allows measurement of both surface characteristics without rearranging the system components. One example interferometric system includes a laser light source and a low coherence light source that alternatively provide light to a collimator, followed by a polarizer, and a polarizing beam splitter. The system further includes two optical filters, a quarter waveplate, two objectives and a reference optical component. Each light source produces a set of interferograms, where one set of interferograms is used to measure the surface shape and another set of interferograms is used to measure the surface roughness of the optical component. |
| FILED | Wednesday, April 28, 2021 |
| APPL NO | 17/997473 |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/0203 (20130101) G01B 9/02027 (20130101) Original (OR) Class G01B 9/02041 (20130101) G01B 11/30 (20130101) G01B 2290/70 (20130101) Optical Elements, Systems, or Apparatus G02B 5/08 (20130101) G02B 5/3025 (20130101) G02B 27/283 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230168081 | GU |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Foundation for The State Unviersity of New York (Albany, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | XIANFENG GU (, None) |
| ABSTRACT | Systems and methods for 3D image scanner for real-time, dynamic 3D surface imaging are disclosed. Embodiments of the present system and methods describe a system and method including a first and/or second, camera, and projector projecting structured light with fringe patterns onto a 3D object, and a processor configured to extract a phase map and a texture image from the image, and to calculate depth information from the phase map by the processor. Embodiments further describe methods and systems for determining an wrapped phase from the images using the Hilbert transformation, generating an absolute phase from the wrapped phase using the combination of a quality-guidance path following algorithm, a double wavelength phase unwrap algorithm, or a Markov Random field method, and generating a phase map from the absolute phase to determine depth information of the 3D object. The captured 3D geometric surfaces are registered, tracked using algorithms of conformal map, optimal transportation map and a Teichmuller map. |
| FILED | Monday, April 12, 2021 |
| APPL NO | 17/917937 |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/2527 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/60 (20130101) G06T 7/521 (20170101) G06T 7/593 (20170101) G06T 17/20 (20130101) G06T 2207/10024 (20130101) G06T 2207/30088 (20130101) G06T 2207/30201 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230168084 | Krovi |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RAYTHEON BBN TECHNOLOGIES, CORP. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hari Kiran Krovi (Lexington, Massachusetts) |
| ABSTRACT | Method for estimating separation distances between a plurality of image sources in a multi-point source imaging system includes: receiving a plurality of light beams, each from a respective image source and having a quantum state mode; constructing a point spread function (PSF) for light beams specific to a symmetry of the image sources; calculating a quantum Fourier transform on the quantum state mode of the plurality of light beams that achieves a quantum limit in a paraxial approximation regime to estimate separation of image sources at the quantum limit to transform the light beams; detecting the transformed light beams to generate electrical signals from respective transformed light beams; and performing signal processing on the electrical signals to estimate the separation distances between the plurality of image sources. |
| FILED | Friday, May 27, 2022 |
| APPL NO | 17/827568 |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 3/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230168187 | Gupta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nikira Labs Inc. (Mountain View, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Manish Gupta (Mountain View, California); Rupal Gupta (Mountain VIew, California) |
| ABSTRACT | An optical system for performing an absorption measurement of a medium sample includes a laser source configured to output a laser beam having a wavelength corresponding to an absorption region of interest; a ringdown cavity comprising a chamber configured to receive the medium sample, an input mirror at an input end, an output mirror at an output end, and an optical axis that extends through the centers of the input mirror and the output mirror; a coupling device configured to couple the laser beam through the input mirror into the chamber; and a detector optically coupled with the cavity, and configured to detect an intensity of light of the wavelength corresponding to the absorption region of interest that extends through the output mirror, wherein a cavity geometry of the cavity increases the re-entrant condition of the cavity relative to a conventional cavity comprised of two spherical mirrors. |
| FILED | Wednesday, January 25, 2023 |
| APPL NO | 18/101448 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/31 (20130101) Original (OR) Class G01N 2201/0231 (20130101) G01N 2201/0633 (20130101) G01N 2201/0636 (20130101) G01N 2201/06113 (20130101) Optical Elements, Systems, or Apparatus G02B 5/10 (20130101) G02B 27/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230168198 | Yager et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Paul Yager (Seattle, Washington); Kamal Girish Shah (Seattle, Washington) |
| ABSTRACT | Systems and methods for detecting a target moiety are disclosed. A system includes a substrate holder including a porous matrix. The porous matrix includes a first detectable agent and a second detectable agent. The system includes a housing, optically coupled with the substrate holder, and shaped to optically couple with a radiation source and a radiation sensor and to optically isolate the radiation source and the radiation sensor. The system includes an excitation filter, disposed in or on the housing, configured to receive excitation electromagnetic radiation from the radiation source and to transmit a first portion of the excitation electromagnetic radiation to the porous matrix. The system also includes an emission filter, disposed in or on the housing, configured to receive emitted fluorescence electromagnetic radiation from the porous matrix and to transmit a second portion of the emitted fluorescence electromagnetic radiation, the second portion being different from the first portion. |
| FILED | Tuesday, August 10, 2021 |
| APPL NO | 17/999803 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6844 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 21/6456 (20130101) Original (OR) Class G01N 2021/6419 (20130101) G01N 2021/6421 (20130101) G01N 2021/6441 (20130101) G01N 2021/6471 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230168482 | Liang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rongguang Liang (Tucson, Arizona); Xiaobo Tian (Tucson, Arizona) |
| ABSTRACT | Snapshot phase-shifting diffraction modules and associated systems and methods are described that enable high spatial and temporal resolution phase imaging with high immunity to environmental factors such as vibrations and temperature changes. One example optical diffraction phase module includes a polarization grating to produce two circularly polarized light beams with opposite polarizations, a first lens to receive the two circularly polarized beams, and a spatial filter positioned at a focal plane of the first lens. The spatial filter includes two openings, one to spatially filter one of the two circularly polarized light beams, and another opening to allow another circularly polarized light beam to pass. The module also includes a second lens to focus the received light onto an image plane and to enable a phase measurement based a plurality of interferograms. The phase module can be incorporated into a microscope system that operates a reflection or a transmission mode. |
| FILED | Thursday, May 06, 2021 |
| APPL NO | 17/998061 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/3083 (20130101) G02B 21/0032 (20130101) G02B 21/0068 (20130101) Original (OR) Class G02B 27/46 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230169673 | Krovi |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RAYTHEON BBN TECHNOLOGIES, CORP. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | RAYTHEON BBN TECHNOLOGIES, CORP. (Cambridge, Massachusetts) |
| INVENTOR(S) | Hari Kiran Krovi (Lexington, Massachusetts) |
| ABSTRACT | An optical circuit for estimating separation distances between N image sources includes an aperture for receiving N light beams and producing a point spread function specific to a symmetry of the image sources from the plurality of light beams; first optical phase shifters to shift the quantum state modes of (N-1) light beams by ɯNN; first beamsplitters, each for mixing respective pairs of quantum state modes of outputs of the first optical phase shifters for a quantum superposition of the respective pairs of the quantum state modes; second beamsplitters, each for mixing respective outputs of the first beamsplitters alternatively; second phase shifters to further shift outputs of the second beamsplitters; N detectors for converting each of the received N light beams to an analog signal; and a signal processing circuit for performing signal processing on the analog signals to estimate the separation distances. |
| FILED | Friday, May 27, 2022 |
| APPL NO | 17/827572 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/10 (20130101) Image Data Processing or Generation, in General G06T 7/70 (20170101) Original (OR) Class G06T 2207/20056 (20130101) G06T 2207/20076 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230170426 | Roth et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Joseph Roth (Elgin, North Dakota); Roman Engel-Herbert (Port Matilda, Pennsylvania) |
| ABSTRACT | The present disclosure relates to transparent conducting films (TCF). In particular, the disclosed TCF are transparent to ultraviolet (UV) light. The TCF can be grown by radio frequency (RF) sputtering and remain in the advantageous perovskite phase. Optical stacks made of substrates with deposited TCF are also disclosed. |
| FILED | Thursday, April 22, 2021 |
| APPL NO | 17/920605 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/022466 (20130101) Original (OR) Class H01L 33/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230170740 | Sarwat et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arif I. Sarwat (Miami, Florida); Hassan Jafari (Miami, Florida) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Arif I. Sarwat (Miami, Florida); Hassan Jafari (Miami, Florida) |
| ABSTRACT | Power controllers (e.g., inductive power transfer (IPT) power controllers) and methods of making and using the same are provided. An IPT power controller can be implemented on direct alternating current (AC)-AC converters and can use only current and voltage measurements to produce multi-power level IPT controller and design switching logic. Using Boolean operators (e.g., AND, OR, Not) applied on a resonant current signal, varying positive energy injections (e.g., 1 to 16 pulses), and varying negative energy injections (e.g., 1 to 16 pulses), up to 32 different active states can be designed. |
| FILED | Tuesday, November 29, 2022 |
| APPL NO | 18/059567 |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/00712 (20200101) H02J 50/12 (20160201) Original (OR) Class Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/083 (20130101) H02M 5/2932 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230171147 | Farritor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shane Farritor (Lincoln, Nebraska); Tyler Wortman (Grand Island, Nebraska); Kyle Strabala (Pittsburgh, Pennsylvania); Ryan McCormick (Valencia, California); Amy Lehman (York, Nebraska); Dmitry Oleynikov (Omaha, Nebraska); Eric Markvicka (Lincoln, Nebraska) |
| ABSTRACT | Various medical devices and related systems, including robotic and/or in vivo medical devices, and various robotic surgical devices for in vivo medical procedures. Included herein, for example, is a robotic surgical system having a support beam positionable through an incision, and a robotic device having a device body, first and second rotating shoulder components coupled to the device body, and first and second robotic arms coupled to the first and second shoulder components, respectively. |
| FILED | Tuesday, January 24, 2023 |
| APPL NO | 18/158810 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/30 (20160201) A61B 90/30 (20160201) A61B 90/361 (20160201) A61B 2034/302 (20160201) Manipulators; Chambers Provided With Manipulation Devices B25J 9/06 (20130101) B25J 9/0087 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 2219/40418 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 41/0631 (20130101) Original (OR) Class H04L 43/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230171385 | Chakravarthula et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Praneeth Kumar Chakravarthula (Carrboro, North Carolina); Felix Heide (Princeton, New Jersey); Ethan Tseng (Princeton, New Jersey); Tarun Srivastava (North Point, China Hong Kong) |
| ABSTRACT | A method for learned hardware-in-the-loop phase retrieval for holographic near-eye displays includes generating simulated ideal output images of a holographic display. The method further includes capturing real output images of the holographic display. The method further includes learning a mapping between the simulated ideal output images and the real output images. The method further includes using the learned mapping to solve for an aberration compensating hologram phase and using the aberration compensating hologram phase to adjust a phase pattern of a spatial light modulator of the holographic display. |
| FILED | Tuesday, November 29, 2022 |
| APPL NO | 18/071065 |
| CURRENT CPC | Holographic Processes or Apparatus G03H 1/2294 (20130101) G03H 2226/02 (20130101) Pictorial Communication, e.g Television H04N 9/01 (20230101) H04N 9/73 (20130101) H04N 9/3182 (20130101) Original (OR) Class H04N 13/257 (20180501) H04N 13/275 (20180501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230171982 | Slinker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jason D. Slinker (Allen, Texas); Aditya Kumar Mishra (Dallas, Texas); Riya Bose (Dallas, Texas); Anton Malko (McKinney, Texas) |
| ABSTRACT | Active emissive layers (e.g., of a light-emitting electrochemical cell (LEC)) are provided and can comprise zero-dimensional (0D) perovskite material in combination with a three-dimensional (3D) perovskite material, as well as electroluminescent devices (e.g., LECs) utilizing such active emissive layers and methods of fabricating and using such active emissive layers and electroluminescent devices. The 0D perovskite material can be incorporated into a matrix film of the 3D perovskite material. The 0D perovskite material can be, for example, perovskite nanocrystals (PNCs). The 0D perovskite material can be, for example, Cs4PbBr6, and the 3D perovskite material can be, for example, CsPbBr3. |
| FILED | Monday, November 28, 2022 |
| APPL NO | 18/059106 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0007 (20130101) H01L 51/0028 (20130101) H01L 51/0035 (20130101) H01L 51/5032 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20230165955 | CURTISS |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Roy CURTISS (Gainesville, Florida) |
| ABSTRACT | Disclosed herein are unique adjuvant compositions comprising an attenuated derivative of a self-destructing bacterial pathogen that undergoes lysis in vivo. In exemplary embodiments, the bacterial pathogen is a Salmonella spp. Also disclosed are methods for enhancing an immune response using the adjuvants disclosed herein. |
| FILED | Friday, April 30, 2021 |
| APPL NO | 17/922499 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) Original (OR) Class A61K 2039/522 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230170273 | Ma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhenqiang Ma (Middleton, Wisconsin); Huilong Zhang (Madison, Wisconsin); Shaoqin Gong (Middleton, Wisconsin) |
| ABSTRACT | Flexible transistors and electronic circuits incorporating the transistors are provided. The flexible transistors promote heat dissipation from the active regions of the transistors while preserving their mechanical flexibility and high-frequency performance. The transistor designs utilize thru-substrate vias (TSVs) beneath the active regions of thin-film type transistors on thin flexible substrates. To promote rapid heat dissipation, the TSVs are coated with a material having a high thermal conductivity that transfers heat from the active region of the transistor to a large-area ground. |
| FILED | Thursday, October 06, 2022 |
| APPL NO | 17/938378 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/367 (20130101) H01L 23/3672 (20130101) Original (OR) Class H01L 23/5226 (20130101) H01L 29/778 (20130101) H01L 29/66431 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 20230166554 | Zlotnick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Joel Zlotnick (Arlington, Virginia); Jordan Brough (Leesburg, Virginia); Troy Eberhardt (Centreville, Virginia); Tyra McConnell (Knoxville, Maryland); Elizabeth Gil (Bristow, Virginia); Traci Moran (Rockville, Maryland) |
| ABSTRACT | Examples are directed toward a substrate offset printed with front side markings on a first side and back side markings on a second side. The front side markings and the back side markings have dimensions in a micrometer range. The front side when viewed with reflected light comprises first portions of a plurality of characters. The back side when viewed with reflected light comprises second portions of the plurality of characters. The first portions and the second portions are printed, when viewed with transmitted light, to show the plurality of characters as whole characters having dimensions in the micrometer range. |
| FILED | Friday, October 07, 2022 |
| APPL NO | 17/961951 |
| CURRENT CPC | Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus B42D 25/29 (20141001) B42D 25/342 (20141001) Original (OR) Class B42D 25/378 (20141001) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230169619 | Ahmed et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (ARMONK, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mohamed Nooman Ahmed (Leesburg, Virginia); Fayin Li (Herndon, Virginia) |
| ABSTRACT | A system and method for classifying compartments at a security checkpoint includes classifying a compartment into a first category or a second category using a first stage neural network that analyzes a three-dimensional representation of the compartment extracted from an imaging device coupled to the computing system, and in response to classifying the compartment into the second category, screening the compartment using a second stage neural network that performs image segmentation to isolate a hazardous object present in the compartment. |
| FILED | Monday, November 29, 2021 |
| APPL NO | 17/456667 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/10 (20130101) G01N 23/046 (20130101) G01N 23/083 (20130101) G01N 2223/04 (20130101) G01N 2223/419 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/28 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/10 (20170101) G06T 7/70 (20170101) G06T 2200/04 (20130101) G06T 2207/10081 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30232 (20130101) G06T 2211/40 (20130101) Image or Video Recognition or Understanding G06V 10/82 (20220101) G06V 10/764 (20220101) G06V 20/52 (20220101) G06V 2201/05 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20230165880 | Simard et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, Baltimore (Baltimore, Maryland); The United States Government as represented by the Department of Veterans Affairs (Washington, D.C., District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | J. Marc Simard (Baltimore, Maryland); Vladimir Gerzanich (Elkridge, Maryland); Caron M. Hong (Ellicott City, Maryland) |
| ABSTRACT | The present invention provides methods of reducing lung injury in a subject in need thereof, comprising administering to the subject an effective amount of an agent that inhibits the activity of SUR1. |
| FILED | Friday, April 23, 2021 |
| APPL NO | 17/920946 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/64 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230167065 | Pou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Oregon Health and Science University (Portland, Oregon); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Sovitj Pou (Portland, Oregon); Rolf W. Winter (Portland, Oregon); Michael K. Riscoe (Portland, Oregon); J. Stone Doggett (Portland, Oregon); Aaron Nilsen (Portland, Oregon) |
| ABSTRACT | The present invention provides synthetic methods and novel intermediates in the preparation of 3-aryl Endochin-like quinolone (ELQ) compounds. |
| FILED | Monday, May 10, 2021 |
| APPL NO | 17/998018 |
| CURRENT CPC | Heterocyclic Compounds C07D 215/233 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20230168211 | ZEINOLABEDINZADEH et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONALAERONAUTICS AND SPA (Washington, District of Columbia) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPA (Washington, District of Columbia) |
| INVENTOR(S) | Saeed ZEINOLABEDINZADEH (Chandler, Arizona); Ebrahim AL SERAGI (Mesa, Arizona); Paul GOLDSMITH (Topanga, California) |
| ABSTRACT | A compact, low-power, high image rejection sideband separation receiver is provided. The receiver observes an input radio frequency (RF) signal of multiple spectral lines (spectral observation), then downconverts the signals to intermediate frequency (IF), and then separates the signals to be observed simultaneously in multiple channels. An embodiment is used to observe a signal (G-band) with two spectral lines and utilizes a two stage Weaver architecture to downconvert the signal's frequency, including a combination of mixers in the second stage that achieves the separation of two different channels. |
| FILED | Tuesday, November 29, 2022 |
| APPL NO | 18/059932 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 22/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230171147 | Farritor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shane Farritor (Lincoln, Nebraska); Tyler Wortman (Grand Island, Nebraska); Kyle Strabala (Pittsburgh, Pennsylvania); Ryan McCormick (Valencia, California); Amy Lehman (York, Nebraska); Dmitry Oleynikov (Omaha, Nebraska); Eric Markvicka (Lincoln, Nebraska) |
| ABSTRACT | Various medical devices and related systems, including robotic and/or in vivo medical devices, and various robotic surgical devices for in vivo medical procedures. Included herein, for example, is a robotic surgical system having a support beam positionable through an incision, and a robotic device having a device body, first and second rotating shoulder components coupled to the device body, and first and second robotic arms coupled to the first and second shoulder components, respectively. |
| FILED | Tuesday, January 24, 2023 |
| APPL NO | 18/158810 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/30 (20160201) A61B 90/30 (20160201) A61B 90/361 (20160201) A61B 2034/302 (20160201) Manipulators; Chambers Provided With Manipulation Devices B25J 9/06 (20130101) B25J 9/0087 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 2219/40418 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 41/0631 (20130101) Original (OR) Class H04L 43/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Classified Government Agency
| US 20230168474 | Peters et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Kevin W. Peters (Merrimack, New Hampshire); Gerard J. Pelletier (Amherst, New Hampshire); David E. Thompson (Nashua, New Hampshire) |
| ABSTRACT | An athermalized Short-Wave InfraRed (SWIR) telephoto lens for a tracking camera having, in order, from a remote object to an image plane an aperture stop, a first optical element having a first element first surface radius of 23.21 mm, a first element second surface radius of 46.25 mm, a second optical element having a second element first surface radius of 22.72 mm, a second element second surface radius of 45.58 mm, a third optical element having a third element first surface radius of −56.85 mm, a third element second surface radius of 16.65 mm, where the lens is corrected over a spectral waveband of 1.5 μm to 1.6 μm from −10 C to +65 C, has a length from the first element to the camera of 88 mm, has a telephoto ratio of 0.367, has an F # of 24, and has a focal length of 240 mm. |
| FILED | Tuesday, November 30, 2021 |
| APPL NO | 17/538467 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 13/02 (20130101) G02B 13/14 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14627 (20130101) H01L 27/14649 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 20230167983 | Yashar |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented by the secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Anthony Yashar (Dunn Loring, Virginia) |
| ABSTRACT | A water treatment system treats water to abates bacterial growth and includes a fluid-isolated heat exchanger; a water treatment container that heats water to a high water temperature that is greater than or equal to a kill temperature for bacteria; a hot water delivery conduit including a transitional cooling zone in thermal communication with the fluid-isolated heat exchanger and that provides bacteria-free water from the water treatment container at a safe temperature. |
| FILED | Thursday, January 26, 2023 |
| APPL NO | 18/101624 |
| CURRENT CPC | Domestic- or Space-heating Systems, e.g Central Heating Systems; Domestic Hot-water Supply Systems; Elements or Components Therefor F24D 17/0073 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Interior (DOI)
| US 20230168235 | KESSLER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES GEOLOGICAL SURVEY (Reston, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Samuel C. KESSLER (Campbellsville, Kentucky); Peter J. CINOTTO (Shelbyville, Kentucky) |
| ABSTRACT | In one embodiment, a sampling device includes: an elongated tubular body having a longitudinal axis and a hollow interior enclosed at a top longitudinal end and a bottom longitudinal end of the body and a particulate matter. One or more mesh bags are disposed in the interior of the body and configured to contain the particulate matter inside a first mesh bag. The first mesh bag is an innermost mesh bag contained inside one or more outer mesh bags in a nested configuration when two or more mesh bags are disposed in the interior of the body. The body includes a plurality of body openings or one half lateral side of the body and no body openings on an opposite half lateral side of the body. |
| FILED | Friday, November 19, 2021 |
| APPL NO | 17/531292 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/04 (20130101) G01N 1/4005 (20130101) G01N 1/4077 (20130101) G01N 5/00 (20130101) G01N 33/18 (20130101) Original (OR) Class G01N 2001/4083 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 20230170991 | Jeong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HEWLETT PACKARD ENTERPRISE DEVELOPMENT LP (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hyunmin Jeong (Champaign, Illinois); Sai Rahul Chalamalasetti (Milpitas, California); Marco Fiorentino (Milpitas, California); Peter Jin Rhim (Milpitas, California) |
| ABSTRACT | Examples described herein relate to a method for synchronizing a wavelength of light in an optical device. In some examples, a heater voltage may be predicted for a heater disposed adjacent to the optical device in a photonic chip. The predicted heater voltage may be applied to the heater to cause a change in the wavelength of the light inside the optical device. In response to applying the heater voltage, an optical power inside the optical device may be measured. Further, a check may be performed to determine whether the measured optical power is a peak optical power. If it is determined that measured optical power is the peak optical power, the application of the predicted heater voltage to the heater may be continued. |
| FILED | Wednesday, December 01, 2021 |
| APPL NO | 17/539275 |
| CURRENT CPC | Transmission H04B 10/07955 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 20230165908 | Agulnick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ViaCyte, Inc. (San Diego, California) |
| ASSIGNEE(S) | ViaCyte, Inc. (San Diego, California) |
| INVENTOR(S) | Alan D. Agulnick (San Diego, California); Kevin Allen D’Amour (San Diego, California) |
| ABSTRACT | A human immature endocrine cell population and methods for making an immature endocrine cell population are provided. Specifically, immature beta cells and methods for production of immature beta cells are described. Immature beta cells co-express INS and NKX6.1 and are uni-potent and thereby develop into mature beta cells when implanted in vivo. The mature beta cells in vivo are capable of producing insulin in response to glucose stimulation. |
| FILED | Wednesday, August 24, 2022 |
| APPL NO | 17/894816 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/39 (20130101) Original (OR) Class A61K 35/545 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0676 (20130101) C12N 5/0678 (20130101) C12N 2500/25 (20130101) C12N 2501/15 (20130101) C12N 2501/16 (20130101) C12N 2501/115 (20130101) C12N 2501/117 (20130101) C12N 2501/119 (20130101) C12N 2501/155 (20130101) C12N 2501/195 (20130101) C12N 2501/385 (20130101) C12N 2501/415 (20130101) C12N 2501/727 (20130101) C12N 2501/998 (20130101) C12N 2501/999 (20130101) C12N 2506/02 (20130101) C12N 2506/45 (20130101) C12N 2533/90 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20230168187 | Gupta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nikira Labs Inc. (Mountain View, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Manish Gupta (Mountain View, California); Rupal Gupta (Mountain VIew, California) |
| ABSTRACT | An optical system for performing an absorption measurement of a medium sample includes a laser source configured to output a laser beam having a wavelength corresponding to an absorption region of interest; a ringdown cavity comprising a chamber configured to receive the medium sample, an input mirror at an input end, an output mirror at an output end, and an optical axis that extends through the centers of the input mirror and the output mirror; a coupling device configured to couple the laser beam through the input mirror into the chamber; and a detector optically coupled with the cavity, and configured to detect an intensity of light of the wavelength corresponding to the absorption region of interest that extends through the output mirror, wherein a cavity geometry of the cavity increases the re-entrant condition of the cavity relative to a conventional cavity comprised of two spherical mirrors. |
| FILED | Wednesday, January 25, 2023 |
| APPL NO | 18/101448 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/31 (20130101) Original (OR) Class G01N 2201/0231 (20130101) G01N 2201/0633 (20130101) G01N 2201/0636 (20130101) G01N 2201/06113 (20130101) Optical Elements, Systems, or Apparatus G02B 5/10 (20130101) G02B 27/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. Agency for International Development (USAID)
| US 20230165788 | JOHNSON et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Research Triangle Institute (Research Triangle Park, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Leah Marie JOHNSON (Durham, North Carolina); Linying Alice LI (Durham, North Carolina); Sai Archana KROVI (Morrisville, North Carolina); Ariane VAN DER STRATEN (Kensington, California) |
| ABSTRACT | A reservoir device comprising an active agent formulation contained within a reservoir is described. The active agent formulation comprises more than one active agent. The reservoir is defined by a biodegradable, permeable polymer membrane. The membrane allows for diffusion of the more than one active agent of the formulation there through when positioned subcutaneously in a body of a subject. |
| FILED | Wednesday, April 07, 2021 |
| APPL NO | 17/995542 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) Original (OR) Class A61K 31/57 (20130101) A61K 31/575 (20130101) A61K 31/675 (20130101) A61K 31/7076 (20130101) A61K 45/06 (20130101) A61K 47/34 (20130101) A61K 47/44 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 15/18 (20180101) A61P 31/18 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
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How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, June 01, 2023.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-applications-20230601.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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