FedInvent™ Patent Applications
Application Details for Thursday, July 13, 2023
This page was updated on Friday, July 14, 2023 at 02:34 AM GMT
Department of Health and Human Services (HHS)
| US 20230217977 | Philpot et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rex M. Philpot (Tampa, Florida); Bethany Johns (Tampa, Florida) |
| ABSTRACT | Described herein is a method for reducing tumor volume in a subject, the method including the steps of administering a cancer treatment (administration of at least one chemotherapeutic agent and/or application of radiation) to the subject in conjunction with the administration of choline, a choline metabolite, a choline precursor molecule, or a combination thereof. In another aspect, the disclosure relates to a method for enhancing cognitive response in a subject during cancer treatment, the method including the steps of administering cancer treatment (administration of at least one chemotherapeutic agent and/or application of radiation) to the subject in conjunction with the administration of choline, a choline metabolite, a choline precursor molecule, or a combination thereof. In still another aspect, choline, a choline metabolite, a choline precursor molecule, or a combination thereof can be administered in the form of a choline-enriched diet, a choline supplement, or a combination thereof. In some aspects, the method also enhances the effectiveness of chemotherapy. |
| FILED | Wednesday, March 15, 2023 |
| APPL NO | 18/184618 |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/30 (20160801) A23L 33/40 (20160801) Preparations for Medical, Dental, or Toilet Purposes A61K 31/14 (20130101) Original (OR) Class A61K 31/675 (20130101) A61K 31/704 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230218154 | St. John et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Maie A. St. John (Oakland, California); Peter Andras Pellionisz (Mountain View, California); Oscar M. Stafsudd (Oakland, California) |
| ABSTRACT | A method for imaging tissue is provided. The method includes illuminating a target tissue via a light-emitting diode. The method further includes acquiring a plurality of timed images of the target tissue including an excitation image corresponding to an excitation state of the light-emitting. Additionally, the method includes generating a relative lifetime map of the target tissue based on the plurality of timed images. |
| FILED | Thursday, April 29, 2021 |
| APPL NO | 17/997087 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/043 (20130101) A61B 1/0684 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230218507 | Gu et al. |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Zhen Gu (Los Angeles, California); Hongjun Li (Los Angeles, California) |
| ABSTRACT | Chimeric antigen receptor T cells (CAR T) therapy reached a milestone in eradicating B-cell malignancies, but beneficial effects in solid tumors are not obtained yet. A porous microneedle patch is disclosed that carries CAR T cells to solid tumors (or other cell types). The device is a honeycomb-like porous microneedle patch that accommodates CAR T cells and allows in situ penetration-media seeding of CAR T cells within post-surgical resection of solid tumors. CAR T cells loaded in the pores of the microneedle tips were readily escorted to the tumor in an evenly scattered manner without losing their activity. Such microneedle-mediated local delivery enhanced infiltration and immune stimulation of CAR T cells as compared to direct intratumoral injection. This tailorable patch offers a transformative platform for scattered seeding of living cells for treating a variety of diseases. Other cell types may be loaded into the porous microneedles. |
| FILED | Wednesday, June 09, 2021 |
| APPL NO | 17/925267 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0021 (20130101) Original (OR) Class Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/0015 (20130101) A61M 2037/0023 (20130101) A61M 2037/0038 (20130101) A61M 2037/0046 (20130101) A61M 2037/0061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230218518 | Aceves et al. |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
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| INVENTOR(S) | Seema S. Aceves (Solana Beach, California); Ranjan Dohil (San Diego, California); Quan Nhu (San Diego, California) |
| ABSTRACT | The disclosure relates to methods and compositions to treat an eosinophilic disease or disorder. More particularly, the disclosure provides methods and compositions for treating eosinophilic esophagitis. |
| FILED | Wednesday, January 04, 2023 |
| APPL NO | 18/150152 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/20 (20130101) A61K 9/0095 (20130101) Original (OR) Class A61K 9/4808 (20130101) A61K 31/426 (20130101) A61K 31/573 (20130101) A61K 47/32 (20130101) A61K 47/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230218523 | MECOZZI et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Sandro MECOZZI (Madison, Wisconsin); Moira ESSON (Medina, Ohio) |
| ABSTRACT | The present invention discloses an ionic liquid composition comprising an at least partially hydrophobic ionic liquid, wherein the at least partially hydrophobic ionic liquid comprises a dication comprising two monocationic groups linked by a bridging group wherein the bridging group provides an at least partially hydrophobic character. The composition may also include a hydrophilic ionic liquid. The hydrophobic ionic liquid may include a quaternary ammonium group which may be substituted or unsubstituted, saturated or unsaturated, linear, branched, cyclic or aromatic and the bridging group is a unsubstituted or substituted C3-C10 alkylene or C3-C10 alkoxyalkyl. Also disclosed is a nanoemulsion formulation which includes the ionic liquid compositions, at least one polymer, a hydrophobic liquid, an aqueous liquid, and a hydrophobic or hydrophilic therapeutic agent. Methods to deliver a therapeutic agent by delivering a nanoemulsion and methods to make a nanoemulsion are also disclosed. |
| FILED | Monday, August 15, 2022 |
| APPL NO | 17/887934 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 47/10 (20130101) A61K 47/14 (20130101) A61K 47/20 (20130101) A61K 47/186 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230218537 | Mulder et al. |
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| APPLICANT(S) | Icahn School of Medicine at Mount Sinai (New York, New York) |
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| INVENTOR(S) | Willem Mulder (Eindhoven, Netherlands); Jordi Ochando (New York, New York); Zahi Fayad (Larchmont, New York); Mounia Braza (New York, New York); Raphaël Duivenvoorden (Gelderland, Netherlands); Francois Fay (New York, New York) |
| ABSTRACT | Methods and compositions for inducing long-term tolerance by hybrid nanoparticles are provided. Compositions and formulations comprising hybrid nanoparticles with inherent affinity for innate immune cells are provided. |
| FILED | Tuesday, March 14, 2023 |
| APPL NO | 18/121527 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/5123 (20130101) A61K 9/5169 (20130101) Original (OR) Class A61K 31/436 (20130101) A61K 38/13 (20130101) A61K 45/06 (20130101) A61K 51/1224 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230218617 | Kirkland et al. |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
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| INVENTOR(S) | James L. Kirkland (Rochester, Minnesota); Tamar Tchkonia (Rochester, Minnesota); Yi Zhu (Rochester, Minnesota); Allyson K. Palmer (Rochester, Minnesota); Nathan K. LeBrasseur (Rochester, Minnesota); Jordan D. Miller (Rochester, Minnesota) |
| ABSTRACT | Provided herein are methods and uses for treatment or prophylaxis of a senescent cell associated disease or disorder by administering a senolytic combination comprising dasatinib and quercetin or an analog thereof to a subject in need thereof. In certain embodiments, the senescent cell associated disease or disorder is a cardiovascular disease or disorder, inflanunatory disease or disorder, a pulmonary disease or disorder, a neurological disease or disorder, or a metabolic disease or disorder. |
| FILED | Monday, October 31, 2022 |
| APPL NO | 17/977654 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/352 (20130101) A61K 31/353 (20130101) A61K 31/506 (20130101) Original (OR) Class A61K 31/665 (20130101) A61K 31/7048 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230218622 | Goldberg et al. |
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| APPLICANT(S) | Mezzion Pharma Co., Ltd. (Seoul, South Korea) |
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| INVENTOR(S) | David J. Goldberg (Philadelphia, Pennsylvania); Mark W. Russell (Ann Arbor, Michigan); Kurt R. Schumacher (Ann Arbor, Michigan); James L. Yeager (Lake Forest, Illinois) |
| ABSTRACT | Various methods and compositions for using udenafil, or a pharmaceutical acceptable salt thereof, for improving enhanced liver fibrosis (ELF) score for improving, maintaining/stabilizing, preventing and/or reducing the rate of decline of fibrotic impaired liver function, transforming a fibrotic liver to a less fibrotic liver, maintaining fibrotic liver condition, and/or reversing fibrotic liver condition and function in patients who have fibrotic livers, especially patients having single ventricle heart disease (SVHD) who have undergone Fontan surgery and have Fontan physiology. |
| FILED | Friday, August 12, 2022 |
| APPL NO | 17/887091 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/16 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230218631 | Anderson et al. |
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| APPLICANT(S) | MUSC Foundation for Research Development (Charleston, South Carolina) |
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| INVENTOR(S) | Ethan Anderson (North Charleston, South Carolina); Christopher Cowan (Mount Pleasant, South Carolina) |
| ABSTRACT | Provided are methods for reducing substance consumption by subjects. In some embodiments, the presently disclosed methods include administering to a subject in need thereof a composition that includes an effective amount of an inhibitor of an EHMT2/G9A biological activity. In some embodiments, the inhibitor of an EHMT2/G9A biological activity is a small molecule inhibitor, a nucleic acid-based inhibitor, and anti-EHMT2/G9A antibody or a fragment or derivative thereof, or any combination thereof. Also provided are methods for reducing relapse vulnerability in subjects that have Alcohol Use Disorder (AUD) and/or another substance use disorder. In some embodiments, the presently disclosed methods further include administering at least one additional therapy to subjects, including but not limited to behavioral therapies such as cognitive behavioral therapies. |
| FILED | Tuesday, January 17, 2023 |
| APPL NO | 18/155587 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) A61K 31/404 (20130101) A61K 31/517 (20130101) A61K 31/551 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/32 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230218634 | Szmulewitz et al. |
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| APPLICANT(S) | University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Russell Z. Szmulewitz (Chicago, Illinois); Suzanne D. Conzen (Park Ridge, Illinois) |
| ABSTRACT | Embodiments of the invention are directed to the treatment of subjects with prostate cancer, in particular those with castration resistant prostate cancer, with glucocorticoid receptor antagonists. The prostate cancer may be one that has become resistant to androgen deprivation therapy, for example, by increase in glucocorticoid receptor expression and/or activity. |
| FILED | Friday, December 23, 2022 |
| APPL NO | 18/088400 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) A61K 31/567 (20130101) Original (OR) Class A61K 31/569 (20130101) A61K 31/573 (20130101) A61K 31/4166 (20130101) A61K 45/06 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230218654 | Li |
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| APPLICANT(S) | The Board of Regents of the university of Oklahoma (Norman, Oklahoma) |
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| INVENTOR(S) | Tiangang Li (Edmond, Oklahoma) |
| ABSTRACT | Compositions and methods of treating hyperglycemia in a subject having such a condition are disclosed. An inhibitor compound which causes activity of Cullin RING E3 ligases (CRL) to be reduced is administered to the subject, wherein blood glucose concentration is decreased. In at least certain embodiments insulin secretion and insulin sensitization in the subject are increased. Inhibition of CRL activity, e.g., by decreasing cullin neddylation by inhibiting NEDD8-activating enzyme (NAE), or decreasing cullin activity, e.g., by inhibiting expression of cullins, is shown herein to delay IRS protein turnover in liver cells and muscle cells, thereby increasing cellular response to insulin and decreasing blood glucose. Thus, inhibition of CRLs, for example by inhibiting neddylation, is an effective method to treat hyperglycemia and insulin resistance, and to increase insulin secretion in patients with hyperglycemia, for example due to type-2 diabetes. |
| FILED | Thursday, March 09, 2023 |
| APPL NO | 18/181016 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) A61K 31/7064 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230218677 | Harrell |
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| APPLICANT(S) | MAM Holdings of West Florida, L.L.C. (Palm Harbor, Florida) |
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| INVENTOR(S) | Carl Randall Harrell (Tarpon Springs, Florida) |
| ABSTRACT | A human amniotic fluid formulation has been developed for topical application to the eye, which is useful for the treatment of ocular diseases and injuries including dry eyes, Sjogren's Syndrome, cataracts, burns and injuries to the eye tissues. The formulation is a sterile de-cellularized human amniotic fluid (D-HAF), devoid of amniotic stem cells and elements of micronized membrane or chorion particles. Methods for treating, or preventing various ocular diseases, injuries and disorders using the formulation, optionally in combination with one or more therapeutic, prophylactic or diagnostic agents are described. |
| FILED | Tuesday, March 14, 2023 |
| APPL NO | 18/121385 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/19 (20130101) A61K 9/0048 (20130101) A61K 9/0051 (20130101) A61K 35/50 (20130101) Original (OR) Class A61K 47/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230218684 | Barrangou et al. |
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| APPLICANT(S) | NORTH CAROLINA STATE UNIVERSITY (Raleigh, North Carolina); COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colorado) |
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| INVENTOR(S) | Rodolphe Barrangou (Raleigh, North Carolina); Gregg A. Dean (Fort Collins, Colorado) |
| ABSTRACT | The present disclosure provides materials and methods related to engineered bacteria for use in vaccines. In particular, the present disclosure provides novel compositions and methods for generating vaccine compositions comprising bacteria (e.g., Lactobacillus) engineered to express immunogenic polypeptides and immunogenicity-enhancing adjuvant polypeptides to treat and/or prevent infection from a pathogenic organism (e.g., coronavirus). |
| FILED | Monday, March 29, 2021 |
| APPL NO | 17/995069 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/744 (20130101) Original (OR) Class A61K 2039/523 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/14 (20130101) C07K 14/165 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 15/746 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230218705 | Garza et al. |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
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| INVENTOR(S) | Luis Garza (Baltimore, Maryland); Lloyd Miller (Ellicott City, Maryland); Martin Alphonse (Baltimore, Maryland); Mohameed Islam (Baltimore, Maryland) |
| ABSTRACT | The present invention relates to the field of caspase inhibition. More specifically, the present invention provides compositions and methods utilizing caspase inhibitors to enhance injury repair and to treat bacterial and viral infections. In a specific embodiment, a method for treating a bacterial infection and skin lesions in a patient comprises the step of administering to the patient an effective amount of a caspase inhibitor. |
| FILED | Tuesday, March 30, 2021 |
| APPL NO | 17/916170 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/05 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) A61P 7/00 (20180101) A61P 17/02 (20180101) A61P 31/04 (20180101) A61P 31/12 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230218707 | SUN et al. |
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| APPLICANT(S) | The Curators of the University of MIssouri (Columbia, Missouri) |
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| INVENTOR(S) | HONGMIN SUN (COLUMBIA, Missouri); XIAOQIN ZOU (COLUMBIA, Missouri); XIAO HENG (COLUMBIA, Missouri); XIANJIN XU (COLUMBIA, Missouri); JUAN JI (COLUMBIA, Missouri) |
| ABSTRACT | Disclosed herein are new peptide inhibitors against beta-lactam resistance that can improve the efficacy of currently available antibiotics. Methods of using the peptide inhibitors for treating bacterial infections are also disclosed. |
| FILED | Friday, June 04, 2021 |
| APPL NO | 17/999974 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/43 (20130101) A61K 31/546 (20130101) A61K 38/08 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230218708 | UDUGAMASOORIYA et al. |
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| APPLICANT(S) | University of Houston System (Houston, Texas); The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | University of Houston System (Houston, Texas); The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Damith Gomika UDUGAMASOORIYA (Katy, Texas); Aaron RAYMOND (Houston, Texas); John MINNA (Dallas, Texas) |
| ABSTRACT | Described herein are pharmaceutical compositions containing peptoids of general formula (I), (II), or (III) capable of reducing proliferation of cancer stem cells in a subject and methods of treatment or prophylactic administration of these pharmaceutical compositions to treat cancer. Also provided herein are method of detecting and treating cancerous cell masses by use of peptoids of general formula (I), (II), or (III). |
| FILED | Friday, January 20, 2023 |
| APPL NO | 18/157648 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/08 (20130101) Original (OR) Class A61K 47/64 (20170801) A61K 47/65 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230218718 | GOMER et al. |
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| APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | Richard H. GOMER (College Station, Texas); Darrell PILLING (Bryan, Texas); Tejas KARHADKAR (San Mateo, California) |
| ABSTRACT | The present disclosure relates to methods of treating Coronavirus-Associated Lung Damage (CALD) and cytokine storm using CALD-treating polypeptides. The methods can involve administering serum amyloid P-component to a patient suffering from CALD or cytokine storm. |
| FILED | Monday, June 07, 2021 |
| APPL NO | 18/009230 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1716 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) A61P 37/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230218723 | Ghandehari et al. |
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| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hamidreza Ghandehari (Salt Lake City, Utah); Joseph Cappello (San Diego, California); Azadeh Poursaid (Salt Lake City, Utah); Mark Martin Jensen (Pleasant Grove, Utah) |
| ABSTRACT | Disclosed are methods of treating an aneurysm in a subject comprising administering to the subject a therapeutically effective amount of a composition comprising a SELP. Disclosed are methods of preventing rupture of an aneurysm comprising administering to a subject having an aneurysm a composition comprising a SELP, wherein the SELP is present in the aneurysm and prevents rupture. Also disclosed are methods of embolizing an aneurysm in a subject comprising administering to the subject a therapeutically effective amount of a composition comprising SEEP. Disclosed are methods of treating AVM in a subject comprising administering to the subject a composition comprising a SELP. In some aspects, the SELP embolizes an abnormal blood vessel in the AVM. Disclosed are methods of embolizing an AVM in a subject comprising administering to the subject a therapeutically effective amount of a composition comprising a SELP, wherein the SELP embolizes an abnormal blood vessel in the AVM. |
| FILED | Friday, September 04, 2020 |
| APPL NO | 17/640627 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 38/39 (20130101) Original (OR) Class A61K 49/0034 (20130101) A61K 49/0073 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230218730 | Ranum et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Laura Ranum (Gainesville, Florida); Lauren A. Laboissonniere (Gainesville, Florida) |
| ABSTRACT | Aspects of the disclosure relate to compositions and methods for eliciting (or enhancing) anti-repeat-associated non-ATG (RAN) protein antibody expression or production in a subject. Administration of the compositions according to the methods of the present disclosure may in some embodiments result in decreased levels of RAN protein expression and/or aggregation. Such compositions and methods may therefore be useful for the treatment of diseases and disorders known to be associated with RAN proteins. |
| FILED | Friday, September 18, 2020 |
| APPL NO | 17/762543 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0007 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 2039/53 (20130101) A61K 2039/545 (20130101) A61K 2039/55516 (20130101) A61K 2039/55561 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Peptides C07K 14/4702 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230218745 | MERUELO et al. |
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| FUNDED BY |
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| APPLICANT(S) | New York University (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel MERUELO (Scarborough, New York); Silvana OPP (New York, New York); Antonella SCAGLIONE (San Diego, California); Christine PAMPENO (New York, New York); Alicia Hurtado MARTINEZ (New York, New York); Ziyan LIN (Long Island City, New York) |
| ABSTRACT | Modified alphaviruses encoding a SARS-CoV-2 spike protein or antigenic segment of the SARS-CoV-2 spike protein are provided. The modified alphaviruses include replicative defective Sindbis viruses. The modified viruses express or are administered with an immunomodulatory agent that is an agonist antibody or antigenbinding fragment thereof, or a cytokine, or a combination thereof. Pharmaceutical compositions that include the modified alphaviruses and methods of using the modified alphaviruses and compositions that contain them are provided. The compositions are used to stimulate a therapeutic or protective effect against SARS-CoV-2 infection that includes humoral and cell mediated responses. |
| FILED | Friday, May 28, 2021 |
| APPL NO | 18/000772 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/215 (20130101) Original (OR) Class A61K 2039/5256 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/165 (20130101) C07K 14/5434 (20130101) C07K 16/2878 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230218893 | Babakhani et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Aydin Babakhani (Los Angeles, California); Iman Habibagahi (Los Angeles, California) |
| ABSTRACT | Wirelessly powered and controlled implantable stimulator system in accordance with embodiments of the invention are described. One embodiment includes: a transmitter (TX) coil wirelessly powering and controlling several implantable stimulators though electromagnetic waves that include modulated waveforms that include n-bit passcodes to individually control stimulation of each of the plurality of implantable stimulators; where an implantable stimulator of the several implantable stimulators includes: a receiver (RX) for receiving a modulated waveform from the TX coil, where the implantable stimulator is controlled based on the modulated waveform. |
| FILED | Thursday, January 12, 2023 |
| APPL NO | 18/153869 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0551 (20130101) Original (OR) Class A61N 1/36153 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/001 (20200101) H02J 50/12 (20160201) H02J 50/80 (20160201) H02J 2310/23 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230219044 | Mittal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rajat Mittal (Vienna, Virginia); Jung Hee Seo (Baltimore, Maryland); Hai-Quan Mao (Baltimore, Maryland); Yue Hao (Baltimore, Maryland); Yizong Hu (Baltimore, Maryland) |
| ABSTRACT | A process and a device for continuous micromixing of two fluids is disclosed. The process and the device can be used in particular when micromixing plays an important role, for example, in the yield and characteristics of the products. This is the case for crystallization, precipitation and combustion reactions and for micelle assembly or polyelectrolyte complexation processes. |
| FILED | Thursday, June 10, 2021 |
| APPL NO | 18/001440 |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 25/23 (20220101) Original (OR) Class B01F 25/25 (20220101) B01F 25/101 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230219081 | McCully et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Children`s Medical Center Corporation (Boston, Massachusetts); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James D. McCully (Marblehead, Massachusetts); Douglas B. Cowan (West Roxbury, Massachusetts); Christina A. Pacak (Brookline, Massachusetts); Sidney Levitsky (Boston, Massachusetts) |
| ABSTRACT | Filtration apparatuses, kits, and methods for rapid isolation of intact, viable mitochondria from tissues are described with mitochondria isolated by differential filtration through nylon mesh filters. Mitochondria can be isolated in less than 30 minutes using the filtration apparatuses, kits, and methods described. |
| FILED | Wednesday, October 05, 2022 |
| APPL NO | 17/960655 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5021 (20130101) Original (OR) Class B01L 2200/0631 (20130101) B01L 2300/0681 (20130101) Apparatus for Enzymology or Microbiology; C12M 47/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4077 (20130101) G01N 2001/4088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230219289 | Miller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Jordan S. Miller (Houston, Texas); Ian S. Kinstlinger (Houston, Texas) |
| ABSTRACT | A composition useful in forming a structure in the form of a substantially interconnected vascular network. The composition includes a powder including a carbohydrate powder and an anti-caking agent, where the powder: has a granular form, and has a specific energy of less than 6 millijoules per milliliter (mJ/mL). |
| FILED | Friday, May 21, 2021 |
| APPL NO | 17/999146 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 41/003 (20130101) B29C 64/30 (20170801) B29C 64/118 (20170801) B29C 64/153 (20170801) Original (OR) Class B29C 64/268 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230219893 | Mallipattu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia); Icahn School of Medicine at Mount Sinai (New York, New York); The Research Foundation for the State University of New York (Albany, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sandeep Mallipattu (St. James, New York); Bhaskar Das (West Nyack, New York) |
| ABSTRACT | The present disclosure is concerned with small molecule modulators of KLF15 signaling useful for treating various disorders such as, for example, kidney disease (e.g., chronic kidney disease), heart disease, obesity, or a neurodegenerative disorder (e.g., amyotrophic lateral sclerosis (ALS), Alzheimer's disease, Parkinson's disease, spinal muscular atrophy, traumatic brain injury, vascular dementia, Huntington's disease, mental retardation, and attention deficit and hyperactivity disorder (ADHD)). This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Thursday, March 02, 2023 |
| APPL NO | 18/116593 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/573 (20130101) Acyclic or Carbocyclic Compounds C07C 321/20 (20130101) Heterocyclic Compounds C07D 213/74 (20130101) C07D 213/85 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230219895 | AN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (BETHESDA, Maryland); SHENZHEN XUHUA BIOTECT CO LTD. (LONGGANG DISTRICT, China PRC) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lin-Kun AN (Guangzhou, Guangdong, China PRC); Xiaoru ZHANG (Guangzhou, Guangdong, China PRC); Haowen WANG (Guangzhou, Guangdong, China PRC); Yves Georges POMMIER (Bethesda, Maryland); Evgeny A. KISELEV (Rockville, Maryland); Azhar Ali RAVJI (Bethesda, Maryland); Keli Kisseh AGAMA (Bethesda, Maryland) |
| ABSTRACT | Compounds and pharmaceutically acceptable salts thereof of Formula I are disclosed. Certain compounds and salts of Formula I are active as Top1 and/or Tdp1 inhibitors. The disclosure provides pharmaceutical compositions containing a compound of Formula I as the only active agent, or optionally containing one or more additional active agents. Methods of using compounds of Formula I to treat cancer are provided in this disclosure. The disclosed compounds of Formula I may be used alone to treat cancer, but may also be used in combination with another active agent, such as a Top1 inhibitor, for example, camptothecin or a camptothecin analogue. |
| FILED | Thursday, July 25, 2019 |
| APPL NO | 17/262379 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 221/18 (20130101) Original (OR) Class C07D 491/22 (20130101) C07D 491/056 (20130101) C07D 491/153 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230219896 | Kunos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The USA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The USA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | George Kunos (Bethesda, Maryland); Malliga Iyer (Germantown, Maryland); Resat Cinar (Bethesda, Maryland); Kenner C. Rice (Bethesda, Maryland) |
| ABSTRACT | A compound, or a pharmaceutically acceptable salt or ester thereof, comprising (i) a CB1 receptor mediating scaffold conjugated to (ii) a second therapeutic scaffold. |
| FILED | Friday, February 10, 2023 |
| APPL NO | 18/108264 |
| CURRENT CPC | Heterocyclic Compounds C07D 231/06 (20130101) Original (OR) Class C07D 401/12 (20130101) C07D 403/12 (20130101) C07D 409/12 (20130101) C07D 417/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230219912 | Trippier et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul Trippier (Papillion, Nebraska); Bader Huwaimel (Omaha, Nebraska) |
| ABSTRACT | Provided herein are compounds and methods for modulating the mitochondrial respiratory complex II (CII) and vascular endothelial growth factor (VEGF) pathways. More particularly, provided are inhibitors of the mitochondrial respiratory complex II (CII) and vascular endothelial growth factor (VEGF) pathways and the uses of such inhibitors in regulating diseases and disorders, e.g., to treat cancer. |
| FILED | Wednesday, May 19, 2021 |
| APPL NO | 17/925765 |
| CURRENT CPC | Heterocyclic Compounds C07D 285/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230219933 | Smith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF NOTRE DAME DU LAC (South Bend, Indiana) |
| ASSIGNEE(S) | UNIVERSITY OF NOTRE DAME DU LAC (South Bend, Indiana) |
| INVENTOR(S) | Bradley D. Smith (Granger, Indiana); Donghao Li (South Bend, Indiana) |
| ABSTRACT | The near-infrared window of fluorescent heptamethine cyanine dyes greatly facilitates biological imaging because there is deep penetration of the light and negligible background fluorescence. But dye instability, aggregation, and poor pharmacokinetics are current drawbacks that limit performance and the scope of possible applications. All these limitations are simultaneously overcome with a new molecular design strategy that produces a charge balanced and sterically shielded fluorochrome. The key design feature is a meso-Aryl group that simultaneously projects two shielding arms directly over each face of a linear heptamethine polyene. Cell and mouse imaging experiments compared a shielded heptamethine cyanine dye (and several peptide and antibody bioconjugates) to benchmark heptamethine dyes and found that the shielded systems possess an unsurpassed combination of photophysical, physiochemical and biodistribution properties that greatly enhance bioimaging performance. |
| FILED | Monday, February 22, 2021 |
| APPL NO | 17/996420 |
| CURRENT CPC | Heterocyclic Compounds C07D 403/14 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230219957 | EL-DEIRY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | WAFIK S. EL-DEIRY (PROVIDENCE, Rhode Island); LIZ J. HERNANDEZ BORRERO (PROVIDENCE, Rhode Island) |
| ABSTRACT | The inventors had earlier discovered a class of anticancer xanthine-related drugs that restores p53 activity in tumors with mutated p53 and perturbs an S-phase checkpoint. Based upon the properties of this class of p53-pathway restoring drugs, the inventors developed uses in cancer treatment. The invention provides drug combinations as new therapy regimens due to synthetic lethality in cancer models. |
| FILED | Monday, May 17, 2021 |
| APPL NO | 17/996493 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 473/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230219958 | Suto et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Southern Research Institute (Birmingham, Alabama); UAB Research Foundation (Birmingham, Alabama); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark J. Suto (Homewood, Alabama); Bini Mathew (Hoover, Alabama); Corinne E. Augelli-Szafran (Homewood, Alabama); Marina Fosso Yatchang (Chelsea, Alabama); Mohammad Athar (Hoover, Alabama); Anupam Agarwal (Mountain Brook, Alabama); Ritesh Kumar Srivastava (Vestavial Hills, Alabama); Suhail Muzaffar (Birmingham, Alabama); Jasim Khan (Birmingham, Alabama) |
| ABSTRACT | The present disclosure is concerned with purine diamine compounds for the treatment of conditions associated with BRD4, RIP3K, and/or IL6 signaling dysfunction such as, for example, cancer (e.g., lung cancer, skin cancer, bladder cancer, kidney cancer, liver cancer), arsenicosis, arsenic poisoning, inflammation, skin lesions, dysfunction of systemic organs, and skin blisters. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Tuesday, January 10, 2023 |
| APPL NO | 18/095429 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 39/02 (20180101) Heterocyclic Compounds C07D 473/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230219991 | GIN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ADJUVANCE TECHNOLOGIES, INC. (Lincoln, Nebraska); MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | ADJUVANCE TECHNOLOGIES, INC. (Lincoln, Nebraska); MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York) |
| INVENTOR(S) | David Y. GIN (Lincoln, Nebraska); Eric CHEA (Oakland, California); Alberto FERNANDEZ-TEJADA (Logroño. La Rioja, Spain); Jeffrey GARDNER (New York, New York); Jason LEWIS (New York, New York); Philip LIVINGSTON (New York, New York); J. Tyler MARTIN (Roca, Nebraska); Lars NORDSTROEM (New York, New York); Naga Vara Kishore PILLARSETTY (Jackson Heights, New York); Govind RAGUPATHI (New York, New York); Derek TAN (New York, New York) |
| ABSTRACT | The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases. |
| FILED | Wednesday, March 08, 2023 |
| APPL NO | 18/180421 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7024 (20130101) A61K 39/08 (20130101) A61K 39/39 (20130101) A61K 39/099 (20130101) A61K 2039/10 (20130101) A61K 2039/55583 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/00 (20130101) Original (OR) Class C07H 13/04 (20130101) C07H 13/06 (20130101) C07H 13/08 (20130101) Steroids C07J 63/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220010 | WIMLEY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Administrators of the Tulane Educational Fund (New Orleans, Louisiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | William Charles WIMLEY (New Orleans, Louisiana); Andrew Robert HOFFMANN (New Orleans, Louisiana); Robert F. GARRY (New Orleans, Louisiana) |
| ABSTRACT | Described herein are antiviral peptides, polynucleotides encoding the peptides, and compositions containing the peptides. Furthermore, described herein are methods for using the peptides, polynucleotides, and compositions for treating or inhibiting a viral infection or one or more symptoms of a viral infection. |
| FILED | Wednesday, March 31, 2021 |
| APPL NO | 17/916295 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) A61K 39/215 (20130101) A61K 2039/545 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) A61P 31/16 (20180101) A61P 31/22 (20180101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) C07K 14/001 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220011 | Gao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xiaojing Gao (Los Angeles, California); Michael B. Elowitz (Los Angeles, California) |
| ABSTRACT | Disclosed herein include methods, compositions, and kits suitable for use in detecting the activation level of a signal transducer. In some embodiments, there are provided synthetic protein circuits wherein recruitment of synthetic protein circuit components to an association location upon activation of a signal transducer generates an active effector protein. The effector protein can be configured to carry out a variety of functions when in an active state, such as, for example, inducing cell death. Methods of treating a disease or disorder characterized by aberrant signaling are provided in some embodiments. |
| FILED | Wednesday, December 14, 2022 |
| APPL NO | 18/065880 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/001 (20130101) Original (OR) Class C07K 14/47 (20130101) C07K 2319/02 (20130101) C07K 2319/50 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/506 (20130101) Enzymes C12Y 304/22044 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6803 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220028 | Cai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jianfeng Cai (Tampa, Florida); Sami Abdulkadir (Tampa, Florida) |
| ABSTRACT | Provided herein are novel VEGF mimics, pharmaceutical compositions thereof, and methods of their use in increasing or reducing angiogenesis. |
| FILED | Wednesday, December 21, 2022 |
| APPL NO | 18/069797 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) Peptides C07K 14/475 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220031 | GARCIA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kenan Christopher GARCIA (Palo Alto, California); Caleb R. GLASSMAN (Palo Alto, California) |
| ABSTRACT | The present disclosure relates generally to compositions and methods for modulating signal transduction mediated by interleukin-12 and interleukin-23. In particular, the disclosure provides novel variants of interleukin-12 subunit p40 with reduced binding affinity to IL-12Rβ1. Also provided are compositions and methods useful for producing such IL-12p40 polypeptide variants, as well as methods for modulating IL-12p40-mediated signaling, and/or for the treatment of conditions associated with perturbations of signal transduction mediated by IL-12p40. |
| FILED | Friday, April 16, 2021 |
| APPL NO | 17/995986 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/20 (20130101) A61K 38/208 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/5434 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220075 | Blau et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Helen M. Blau (Stanford, California); Ermelinda Porpiglia (Stanford, California); David M. Burns (Stanford, California) |
| ABSTRACT | The present disclosure provides compositions and methods based on the inhibition of thrombospondin-1 as a therapeutic target in aging skeletal muscle to improve muscle mass, strength, function, maintenance, and regeneration. |
| FILED | Tuesday, June 22, 2021 |
| APPL NO | 18/010452 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Peptides C07K 16/2803 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220085 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Brigham and Women’s Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul B. Yu (Boston, Massachusetts); Luca Troncone (Brookline, Massachusetts); Stephanie Kim (Brookline, Massachusetts) |
| ABSTRACT | Compositions and methods for selective targeting of BMP/TGF? signaling using heteromeric complexes, preferably comprising single chain variable domain (scFv) antibodies (Abs) targeting the extracellular domains of BMP type I and type II receptors. |
| FILED | Monday, March 01, 2021 |
| APPL NO | 17/907781 |
| CURRENT CPC | Peptides C07K 16/2863 (20130101) Original (OR) Class C07K 2317/31 (20130101) C07K 2317/35 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220103 | Turtle et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Fred Hutchinson Cancer Center (Seattle, Washington) |
| ASSIGNEE(S) | Fred Hutchinson Cancer Center (Seattle, Washington) |
| INVENTOR(S) | Cameron J. Turtle (Seattle, Washington); Roland B. Walter (Seattle, Washington); George S. Laszlo (Seattle, Washington); Salvatore Fiorenza (Seattle, Washington) |
| ABSTRACT | Chimeric antigen receptors (CARs) with binding domains derived from a novel suite of human CD33-binding antibodies are described. The CARs include optimized short and intermediate spacer regions. The current disclosure also provides methods of cell expansion/activation processes utilizing IL-2, IL-7, IL-15, and/or IL-21 that improve cellular proliferation and cell lysis of the CARs as described. |
| FILED | Wednesday, March 31, 2021 |
| APPL NO | 17/907648 |
| CURRENT CPC | Peptides C07K 14/7051 (20130101) C07K 14/70521 (20130101) C07K 16/2896 (20130101) Original (OR) Class C07K 2317/526 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) C07K 2319/03 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220113 | GARCIA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AQUALUNG THERAPEUTICS CORP. (TUCSON, Arizona) |
| ASSIGNEE(S) | AQUALUNG THERAPEUTICS CORP. (TUCSON, Arizona) |
| INVENTOR(S) | JOE G.N. GARCIA (TUCSON, Arizona); DARRAGH MACCANN (CO. DERRY, Ireland) |
| ABSTRACT | Anti-nicotinamide phosphoribosyltransferase (NAMPT) antibodies, or antigen binding fragments thereof, are described, as well as methods for treating a subject having a (NAMPT)-associated local and/or systemic inflammatory disorder. |
| FILED | Friday, September 09, 2022 |
| APPL NO | 17/941741 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) A61P 31/14 (20180101) Peptides C07K 16/40 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/34 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220148 | Park et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado); Universita degli Studi di Trieste (Trieste, Italy) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daewon Park (Englewood, Colorado); Brisa Pena Castellanos (Aurora, Colorado); Susanna Bosi (Trieste, Italy); Luisa Mestroni (Boulder, Colorado); Maurizio Prato (Trieste, Italy) |
| ABSTRACT | Polymers suitable for forming carbon nanotube-functionalized reverse thermal gel compositions, compositions including the polymers, and methods of forming and using the polymers and compositions are disclosed. The compositions have reverse thermal gelling properties and transform from a liquid/solution to a gel—e.g., near or below body temperature. The polymers and compositions can be injected into or proximate an area in need of treatment. |
| FILED | Tuesday, March 21, 2023 |
| APPL NO | 18/124219 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/174 (20170801) C01B 2202/06 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2006/22 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 83/001 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0657 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220334 | SINGEC et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN S (Rockville, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ilyas SINGEC (Gaithersburg, Maryland); Jaroslav SLAMECKA (Gaithersburg, Maryland); Anton SIMEONOV (Bethesda, Maryland); Tao DENG (Potomac, Maryland) |
| ABSTRACT | Methods for generating in culture of cells resembling mammalian trophectoderm-lineage cells from mammalian pluripotent stem cells are provided, along with the related compositions. |
| FILED | Wednesday, June 02, 2021 |
| APPL NO | 18/000653 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0605 (20130101) Original (OR) Class C12N 2500/02 (20130101) C12N 2501/11 (20130101) C12N 2501/12 (20130101) C12N 2501/13 (20130101) C12N 2501/15 (20130101) C12N 2501/115 (20130101) C12N 2501/155 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220335 | Chambers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN KETTERING CANCER CENTER (NEW YORIK, New York) |
| ASSIGNEE(S) | MEMORIAL SLOAN KETTERING CANCER CENTER (NEW YORK, New York) |
| INVENTOR(S) | Stuart Chambers (San Francisco, California); Lorenz Studer (New york, New York) |
| ABSTRACT | The present invention relates generally to the field of cell biology of stem cells, more specifically the directed differentiation of pluripotent or multipotent stem cells, including human embryonic stem cells (hESC), somatic stem cells, and induced human pluripotent stem cells (hiPSC) using novel culture conditions. Specifically, methods are provided for obtaining neural tissue, floor plate cells, and placode including induction of neural plate development in hESCs for obtaining midbrain dopamine (DA) neurons, motor neurons, and sensory neurons. Further, neural plate tissue obtained using methods of the present inventions are contemplated for use in co-cultures with other tissues as inducers for shifting differentiation pathways, i.e. patterning. |
| FILED | Wednesday, January 11, 2023 |
| APPL NO | 18/153038 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) Original (OR) Class C12N 2500/90 (20130101) C12N 2501/15 (20130101) C12N 2501/41 (20130101) C12N 2501/60 (20130101) C12N 2501/155 (20130101) C12N 2501/415 (20130101) C12N 2501/998 (20130101) C12N 2506/02 (20130101) C12N 2506/45 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220342 | LIU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia State University Research Foundation, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yuan LIU (Decatur, Georgia); Zhen BIAN (Atlanta, Georgia); Lei SHI (Decatur, Georgia); Ke ZEN (Decatur, Georgia); Koby KIDDER (Mohnton, Pennsylvania) |
| ABSTRACT | As disclosed herein, SIRPα is integral to immuno-evasion by many different cancer types as well as cancer resistance to therapies, and reducing SIRPα levels on can bolster antigen acquisition, processing, and presentation, decrease TME immunosuppression and thereby promote tumor-specific T cell activation to eliminate tumors and generate an adaptive immune response consisting of memory T cells, circulating antibodies, and plasma cells, all of which may be specific for neo-antigens in the original cancer. Therefore, disclosed are activated SIRPαlow macrophages that are useful for treating cancers. |
| FILED | Friday, April 23, 2021 |
| APPL NO | 17/996573 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/15 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 5/0645 (20130101) Original (OR) Class C12N 2501/24 (20130101) C12N 2501/999 (20130101) C12N 2502/1114 (20130101) C12N 2502/1157 (20130101) C12N 2506/115 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220361 | KAMINSKI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rafal KAMINSKI (Philadelphia, Pennsylvania); Tricia BURDO (Dresher, Pennsylvania) |
| ABSTRACT | Migration of HIV-1 infected monocytes across the endothelial barrier plays an essential role in establishing and maintenance of viral reservoir in the brain and leads to neuroinflammation, neuronal damage, and subsequent HIV-induced central nervous system (CNS) dysfunction. These processes continue despite antiretroviral therapy (ART) due to limited pharmacological permeability of the blood-brain barrier, the presence of residual viral replication, and the reactivation of latent viruses. Compositions comprising Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated endonucleases targeted to activated leukocytes cell adhesion molecule (ALCAM/CD166), chemotactic recruitment (CCR2/5), adhesion to the endothelium (ALCAM) and junctional diapedesis (JAM-A) achieves maximum repression of leukocyte transmigration and block of the spread of the virus to different tissues and organs. |
| FILED | Friday, August 05, 2022 |
| APPL NO | 17/817781 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220374 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BROAD INSTITUTE, INC. (CAMBRIDGE, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (CAMBRIDGE, Massachusetts) |
| ASSIGNEE(S) | THE BROAD INSTITUTE, INC. (CAMBRIDGE, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (CAMBRIDGE, Massachusetts) |
| INVENTOR(S) | David R. Liu (Cambridge, Massachusetts); Andrew Vito Anzalone (Cambridge, Massachusetts); Jonathan Ma Levy (Cambridge, Massachusetts); Xin Gao (Cambridge, Massachusetts); Christopher J. Podracky (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure provides systems, compositions, and methods for simultaneously editing both strands of a double-stranded DNA sequence at a target site to be edited. In some aspects, the systems comprise a first and second prime editor complex, wherein each of the first and second prime editor complexes comprises (1) a prime editor comprising (i) a nucleic acid programmable DNA binding protein (napDNAbp), and (ii) a polypeptide having an RNA-dependent DNA polymerase activity; and (2) a pegRNA comprising a spacer sequence, gRNA core, a DNA synthesis template, and a primer binding site, wherein the DNA synthesis template encodes a desired DNA sequence or a complement thereof, wherein the desired DNA sequence and the complement thereof form a duplex comprising an edited portion which integrates into the target site to be edited. In some aspects, the systems comprise a first, second, third, and fourth prime editor complex, each comprising a prime editor and a PEgRNA. Also provided herein are methods for simultaneously editing both strands of a double-stranded DNA sequence at a target site to be edited. Further provided herein are pharmaceutical compositions, polynucleotides, vectors, cells, and kits. |
| FILED | Monday, November 07, 2022 |
| APPL NO | 18/053269 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/1276 (20130101) C12N 15/102 (20130101) Original (OR) Class C12N 15/111 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220385 | Kortylewski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | City of Hope (Duarte, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Marcin Tomasz Kortylewski (Monrovia, California); Guido Marcucci (Azusa, California); Yu-Lin Su (Duarte, California); Piotr Marek Swiderski (San Dimas, California) |
| ABSTRACT | The disclosure provides, inter alia, hybridized nucleic acid sequences and compounds comprising Toll-like receptor 9-binding nucleic acid sequences and nucleic acid sequences comprising a microRNA passenger strand sequence hybridized to a microRNA guide strand sequence; pharmaceutical compositions comprising the hybridized nucleic acid sequences and compounds; and the use of the hybridized nucleic acid sequences, compounds, and pharmaceutical compositions to treat medical conditions, such as cancer and inflammatory diseases. |
| FILED | Wednesday, November 25, 2020 |
| APPL NO | 17/779293 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/141 (20130101) C12N 2310/3519 (20130101) C12N 2320/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220401 | SIERKS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael SIERKS (Fort McDowell, Arizona); Lalitha VENKATARAMAN (Tempe, Arizona); Wei XIN (Tempe, Arizona) |
| ABSTRACT | The present invention provides detection reagents and method for determining risk of traumatic brain injury (TBI) and/or susceptibility to neurodegenerative disease in a subject. |
| FILED | Tuesday, December 20, 2022 |
| APPL NO | 18/085418 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Peptides C07K 1/22 (20130101) C07K 16/18 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) G01N 2800/2821 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220443 | BURGOS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Emmanuel Sebastien BURGOS (Bronx, New York); David SHECHTER (New Rochelle, New York) |
| ABSTRACT | Methods and kits are disclosed for measuring activity of a methyltransferase or a radical SAM enzyme or for screening for an inhibitor of a methyltransferase or a radical SAM enzyme, where the methods and kits comprise, respectively, deaminase TM0936 for a MTase coupled assay and deaminase PA3170 for a radical SAM coupled assay. |
| FILED | Tuesday, February 20, 2018 |
| APPL NO | 16/488421 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/34 (20130101) C12Q 1/48 (20130101) Original (OR) Class Enzymes C12Y 201/01 (20130101) C12Y 305/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220456 | ZHANG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | David ZHANG (Houston, Texas); Ruojia WU (Houston, Texas); Peng DAI (Houston, Texas); Xi CHEN (Houston, Texas) |
| ABSTRACT | Provided herein are methods for labeling input DNA with oligonucleotide barcode sequences, and selective PCR amplification of DNA sequence variants across the targeted regions for variant quantitation. |
| FILED | Friday, April 30, 2021 |
| APPL NO | 17/997696 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6851 (20130101) Original (OR) Class C12Q 1/6858 (20130101) C12Q 1/6869 (20130101) C12Q 1/6876 (20130101) C12Q 2600/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220468 | HATCHWELL et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Research Foundation of State of University of New York (Albany, New York); Population Bio, Inc. (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eli HATCHWELL (Winchester, United Kingdom); Peggy S. EIS (Fitchburg, Wisconsin) |
| ABSTRACT | This document provides methods and materials related to genetic variations of neurological disorders. For example, this document provides methods for using such genetic variations to assess susceptibility of developing Parkinson's disease. |
| FILED | Wednesday, October 20, 2021 |
| APPL NO | 17/506406 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6809 (20130101) C12Q 1/6813 (20130101) C12Q 1/6827 (20130101) C12Q 1/6869 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/48 (20130101) G01N 33/5005 (20130101) G01N 33/5023 (20130101) G01N 33/5058 (20130101) G01N 33/6896 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220472 | Ganesh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); The University of British Columbia (Vancouver, Canada) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Santhi Ganesh (Ann Arbor, Michigan); Liam Brunham (Vancouver, Canada); Jacqueline Saw (Vancouver, Canada) |
| ABSTRACT | Provided herein are systems and methods for determining a subject's risk of spontaneous coronary artery dissection (SCAD) and myocardial infarction (MI) and systems and methods of using SCAD and/or MI risk for treatment thereof. |
| FILED | Friday, May 28, 2021 |
| APPL NO | 18/000060 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/616 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220475 | Griffin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Patrick Thomas Griffin (Cambridge, Massachusetts); David A. Sinclair (Cambridge, Massachusetts) |
| ABSTRACT | The present invention provides methods, compositions and kits for assembling an enzyme-deoxyribonucleic acid (DNA) complex for use in preparing a double stranded DNA molecule comprising one or more loci of interest for determining the methylation status of the one or more loci of interest therein. |
| FILED | Friday, June 11, 2021 |
| APPL NO | 18/008989 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/154 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220589 | GUNDERSON et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Encodia, Inc. (San Diego, California) |
| ASSIGNEE(S) | Encodia, Inc. (San Diego, California) |
| INVENTOR(S) | Kevin L. GUNDERSON (San Diego, California); Soumya GANGULY (San Diego, California); Robert C. JAMES (San Diego, California); Kenneth KUHN (San Diego, California); Zachary MILES (San Diego, California); Lei SHI (San Diego, California); Stephen VERESPY, III (San Diego, California); Aaron WISE (San Diego, California); Zongxiang ZHOU (San Diego, California) |
| ABSTRACT | The present disclosure relates to a binder that specifically binds to an N-terminally modified polypeptide through interaction with a modified N-terminal amino acid. Also provided herein is a method and related kits for treating a polypeptide using or comprising the binder and/or modified cleavase. In some embodiments, also provided herein is a method and related kits for transferring information using a plurality of enzymes, including for performing a ligation, extension, and cleavage reaction with nucleic acid molecules associated with the polypeptide for analysis. |
| FILED | Wednesday, September 29, 2021 |
| APPL NO | 17/539033 |
| CURRENT CPC | Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230221239 | PRALJAK et al. |
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| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Niksa PRALJAK (Cleveland, Ohio); Shamreen IRAM (Cleveland, Ohio); Utku GOREKE (Cleveland, Ohio); Michael HINCZEWSKI (Cleveland, Ohio); Ailis HILL (Cleveland, Ohio); Umut GURKAN (Cleveland, Ohio); Gundeep SINGH (Cleveland, Ohio) |
| ABSTRACT | In a disclosed example, a computer-implemented method includes storing image data that includes an input image of a blood sample within a blood monitoring device. The method also includes generating, by a machine learning model, a segmentation mask that assigns pixels in the input image to one of a plurality of classes, which correlate to respective known biophysical properties of blood cells. The method also includes extracting cell images from the input image based on the segmentation mask, in which each extracted cell image includes a respective cluster of the pixels assigned to a respective one of the plurality of classes. |
| FILED | Thursday, June 03, 2021 |
| APPL NO | 17/928976 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1475 (20130101) Original (OR) Class G01N 33/49 (20130101) G01N 2015/0073 (20130101) Image Data Processing or Generation, in General G06T 7/12 (20170101) Image or Video Recognition or Understanding G06V 10/25 (20220101) G06V 10/762 (20220101) G06V 10/764 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230221313 | DeKosky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts); University of Kansas (Lawrence, Kansas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brandon DeKosky (Cambridge, Massachusetts); Matias F. Gutierrez (Cambridge, Massachusetts); Chengyu Chung (Lawrence, Kansas); Ahmed Fahad (Lawrence, Kansas); Nicoleen Boyle (Lawrence, Kansas); Shuyan Jin (Lawrence, Kansas) |
| ABSTRACT | Disclosed herein are methods, compositions, systems, and kits related to functional testing of soluble polypeptides in a single-cell format. |
| FILED | Friday, November 11, 2022 |
| APPL NO | 18/054823 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/566 (20130101) Original (OR) Class G01N 33/56983 (20130101) G01N 2500/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230221318 | Hess et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicholas Hess (Cottage Grove, Wisconsin); Christian Capitini (Madison, Wisconsin); Kalyan Nadiminti (Madison, Wisconsin); Peiman Hematti (Madison, Wisconsin); Jenny Gumperz (Madison, Wisconsin) |
| ABSTRACT | The present disclosure generally relates to methods for diagnosing, predicting and treating graft-vs-host disease and/or relapse of a hematologic malignancy following hematopoietic stem cell transplantation based on T-cell specific biomarkers. |
| FILED | Friday, January 06, 2023 |
| APPL NO | 18/094221 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56972 (20130101) Original (OR) Class G01N 2333/70589 (20130101) G01N 2800/245 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230221337 | KATAGIRI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE (Tokyo, Japan); TIMEWELL MEDICAL Co., Ltd. (Tokyo, Japan) |
| ASSIGNEE(S) | NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE (Tokyo, Japan); TIMEWELL MEDICAL Co., Ltd. (Tokyo, Japan) |
| INVENTOR(S) | Daisuke KATAGIRI (Tokyo, Japan); Eisei NOIRI (Tokyo, Japan); Norio OHMAGARI (Tokyo, Japan); Takeshi SUGAYA (Tokyo, Japan) |
| ABSTRACT | The purpose of the present invention is to provide: a method for testing the aggravation risk for a person infected with the COVID-19 virus, the method allowing the use of urine as a test sample; a test kit for the method; and a companion diagnostic drug and an aggravation risk marker thereof. The present invention is a method that includes a step for determining the amount of liver fatty acid binding protein in urine sampled from a subject, and that tests the aggravation risk of SARS-CoV-2 infectious disease (COVID-19) on the basis of the quantitative determination result. |
| FILED | Thursday, June 18, 2020 |
| APPL NO | 17/928371 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) Original (OR) Class G01N 2800/26 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230221541 | Shroff et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hari Shroff (Ashburn, Virginia); Patrick La Riviere (Chicago, Illinois); Yicong Wu (Bethesda, Maryland); Xiaofei Han (Beijing, China PRC) |
| ABSTRACT | Methods and systems are provided for improving resolution, acquisition speed, and/or illumination dose for microscopy systems. In some embodiments, a microscopy system having multiple objective setups may include illumination generators to provide selectively-blanked illumination line scans, objective lenses to introduce the selectively-blanked illumination line scans to a sample and to collect fluorescence emissions from the sample, and detectors to receive the fluorescence emissions from the objective lenses. The microscopy system may also include one or more processors in operative communication with the detectors, which may combine the fluorescence emissions to generate a composite image. |
| FILED | Friday, March 26, 2021 |
| APPL NO | 17/995271 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) Optical Elements, Systems, or Apparatus G02B 21/0076 (20130101) G02B 21/367 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230221578 | Yoon |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Geunyoung Yoon (Houston, Texas) |
| ABSTRACT | A method comprises positioning, on a subject's eye, an ophthalmic lens having one or more physical marks, directing light through the eye to cause reflection of light off the retina of the eye, visualizing one or more images representative of the at least one physical mark and determining an orientation of the ophthalmic lens based on the one or more images. |
| FILED | Tuesday, December 27, 2022 |
| APPL NO | 18/088967 |
| CURRENT CPC | Spectacles; Sunglasses or Goggles Insofar as They Have the Same Features as Spectacles; Contact Lenses G02C 7/021 (20130101) Original (OR) Class G02C 7/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230222637 | Keahey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Pelham Keahey (Missouri City, Texas); Rebecca Richards-Kortum (Houston, Texas) |
| ABSTRACT | A high-resolution microendoscope system includes a light source, a fiber optic bundle configured to transmit light from the light source to a sample, a disc configured to receive light returned from the sample, the disc having spaced apart segments, the spaced-apart segments being at least one of openings and transparent portions, a first camera configured to capture a first image based at least in part on light passing through the disc, and a second camera configured to capture a second image based at least in part on light reflected from the disc. |
| FILED | Monday, November 14, 2022 |
| APPL NO | 18/055237 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/07 (20130101) A61B 1/042 (20130101) A61B 1/043 (20130101) A61B 1/0646 (20130101) Optical Elements, Systems, or Apparatus G02B 23/2469 (20130101) Image Data Processing or Generation, in General G06T 5/003 (20130101) G06T 5/50 (20130101) Original (OR) Class G06T 2207/10064 (20130101) G06T 2207/10068 (20130101) G06T 2207/30096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230222654 | Fan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SPECTRAL MD, INC. (Dallas, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Wensheng Fan (Plano, Texas); John Michael DiMaio (Dallas, Texas); Jeffrey E. Thatcher (Irving, Texas); Peiran Quan (Dallas, Texas); Faliu Yi (Allen, Texas); Kevin Plant (Dallas, Texas); Ronald Baxter (Grand Prairie, Texas); Brian McCall (Dallas, Texas); Zhicun Gao (Plano, Texas); Jason Dwight (Dallas, Texas) |
| ABSTRACT | Machine learning systems and methods are disclosed for prediction of wound healing, such as for diabetic foot ulcers or other wounds, and for assessment implementations such as segmentation of images into wound regions and non-wound regions. Systems for assessing or predicting wound healing can include a light detection element configured to collect light of at least a first wavelength reflected from a tissue region including a wound, and one or more processors configured to generate an image based on a signal from the light detection element having pixels depicting the tissue region, determine reflectance intensity values for at least a subset of the pixels, determine one or more quantitative features of the subset of the plurality of pixels based on the reflectance intensity values, and generate a predicted or assessed healing parameter associated with the wound over a predetermined time interval. |
| FILED | Thursday, March 02, 2023 |
| APPL NO | 18/177493 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0077 (20130101) A61B 5/445 (20130101) A61B 5/7275 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 2207/20081 (20130101) G06T 2207/30088 (20130101) G06T 2207/30096 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230223152 | Wilson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio); UH Cleveland Medical Center (Cleveland, Ohio); Florida Institute of Technology (Melbourne, Florida); Tampa General Hospital (Tampa, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David L. Wilson (Cleveland Heights, Ohio); Yazan Gharaibeh (Shaker Heights, Ohio); Juhwan Lee (Westlake, Ohio); Sadeer Al-Kindi (Lyndhurst, Ohio); Vladislav N. Zimin (Beachwood, Ohio); Linxia Gu (Melbourne, Florida); Pengfei Dong (Melbourne, Florida); Hiram Bezerra (Tampa, Florida) |
| ABSTRACT | The present disclosure, in some embodiments, relates to a method of predicting stent expansion. The method includes accessing a pre-stent intravascular image of a blood vessel of a patient and segmenting the pre-stent intravascular image to identify a lumen and a calcification lesion. A plurality of features are extracted from one or more of the lumen and the calcification lesion. A regression model is applied to one or more of the plurality of features to determine a minimum stent expansion metric (mSEM). The mSEM indicating how much a stent will expand after implantation. The mSEM is used to generate a classification of the blood vessel as an under-expanded area or a well-expanded area. |
| FILED | Thursday, January 05, 2023 |
| APPL NO | 18/150315 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/7264 (20130101) A61B 34/10 (20160201) A61B 2034/104 (20160201) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/10101 (20130101) G06T 2207/20081 (20130101) G06T 2207/30096 (20130101) G06T 2207/30101 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) G16H 50/50 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20230217971 | Qadri et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Syed B. Qadri (Fairfax Station, Virginia); Bhakta B. Rath (Oakton, Virginia); Edward P. Gorzkowski, III (Odenton, Maryland) |
| ABSTRACT | Nano-structures of Aluminum Nitride and a method of producing nano-structures of Aluminum Nitride from nut shells comprising milling agricultural nuts into a fine nut powder, milling nanocrystalline Al2O3 into a powder, mixing, pressing the fine nut powder and the powder of nanocrystalline Al2O3, heating the pellet, maintaining the temperature of the pellet at about 1400° C., cooling the pellet, eliminating the residual carbon, and forming nano-structures of AlN. An Aluminum Nitride (AlN) product made from the steps of preparing powders of agricultural nuts using ball milling, preparing powders of nanocrystalline Al2O3, mixing the powders of agricultural nuts and the powders of nanocrystalline Al2O3 forming a homogenous sample powder of agricultural nuts and Al2O3, pressurizing, pyrolizing the disk, and reacting the disk and the nitrogen atmosphere and forming AlN. |
| FILED | Wednesday, March 08, 2023 |
| APPL NO | 18/118921 |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 25/00 (20160801) Original (OR) Class Crushing, Pulverising, or Disintegrating in General; Milling Grain B02C 17/20 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 21/0726 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/82 (20130101) C01P 2004/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230218226 | Reed et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | David A. Reed (Baltimore, Maryland); George C. Emmett (Wilmington, Delaware) |
| ABSTRACT | In an example, a method of detecting cyanide exposure of an individual includes: measuring a thiocyanate level of the individual which includes placing saliva of the individual in contact with a chemical indicator to measure the thiocyanate level and measuring thiocyanate (SCN−) catalyzed by enzyme rhodanese of the individual; comparing the measured thiocyanate level to a preset thiocyanate threshold to determine whether the measured thiocyanate level is above the preset thiocyanate threshold indicating a level of cyanide poisoning for which a medical procedure is recommended to manage health effects of the exposure; and performing the medical procedure if the measured thiocyanate level is above the preset thiocyanate threshold and not performing the medical procedure if the measured thiocyanate level is not above the preset thiocyanate threshold. |
| FILED | Tuesday, January 17, 2023 |
| APPL NO | 18/097978 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/4845 (20130101) Original (OR) Class A61B 5/14551 (20130101) A61B 10/0051 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230218384 | Powell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brandon Powell (Washington, District of Columbia); John Montgomery (Washington, District of Columbia); Bradley Segelhorst (Washington, District of Columbia); Christopher Ferri (Washington, District of Columbia); Alex Snouffer (Washington, District of Columbia) |
| ABSTRACT | A thermoplastic vascular structure has a first thermoplastic sheet including at least one first recess; and a second thermoplastic sheet. The first thermoplastic sheet is attached to the second thermoplastic sheet to create a continuous branched vascular network structure. The at least one first recess creates at least one fluid channel through the continuous branched vascular network structure. The second thermoplastic sheet may have at least one second recess. The at least one first recess of the first thermoplastic sheet may align with the at least one second recess of the second thermoplastic sheet to create the at least one fluid channel through the continuous branched vascular network structure. |
| FILED | Wednesday, January 04, 2023 |
| APPL NO | 18/093017 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/04 (20130101) Original (OR) Class A61F 2/82 (20130101) A61F 2210/0076 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230218634 | Szmulewitz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Russell Z. Szmulewitz (Chicago, Illinois); Suzanne D. Conzen (Park Ridge, Illinois) |
| ABSTRACT | Embodiments of the invention are directed to the treatment of subjects with prostate cancer, in particular those with castration resistant prostate cancer, with glucocorticoid receptor antagonists. The prostate cancer may be one that has become resistant to androgen deprivation therapy, for example, by increase in glucocorticoid receptor expression and/or activity. |
| FILED | Friday, December 23, 2022 |
| APPL NO | 18/088400 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) A61K 31/567 (20130101) Original (OR) Class A61K 31/569 (20130101) A61K 31/573 (20130101) A61K 31/4166 (20130101) A61K 45/06 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230219075 | PENNELL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | KURT PENNELL (WABAN, Massachusetts); Chen Liu (Providence, Rhode Island) |
| ABSTRACT | This invention relates to an aqueous composition comprising, (a) an ion-exchange resin (IXR) comprising microporous beads having a particle size ranging from about 200 um to about 1000 um; (b) a water soluble surfactant having a molecular weight ranging from about 7,500 to about 15,000 Da; and (c) a buffer component; wherein the pH of the aqueous composition ranges from about 5 to about 8, and a process for isolating chemical contaminants using the aqueous composition. |
| FILED | Tuesday, April 06, 2021 |
| APPL NO | 17/995639 |
| CURRENT CPC | Separation B01D 15/361 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 41/05 (20170101) B01J 41/07 (20170101) B01J 41/12 (20130101) B01J 47/018 (20170101) Original (OR) Class Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/42 (20130101) C02F 1/56 (20130101) C02F 1/547 (20130101) C02F 2001/422 (20130101) C02F 2101/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230219080 | Puleo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher Michael Puleo (Niskayuna, New York); Ralf Lenigk (Schnectady, New York); Tejas Suresh Khire (Niskayuna, New York); Tyler Hammond (Amsterdam, New York); Erik Leeming Kvam (Niskayuna, New York); Allison Caron (Burnt Hills, New York) |
| ABSTRACT | A closed system centrifuge tube is described and discussed herein that enables removal of waste and transfer and removal of samples via one or more ports of the centrifuge tube within the closed system, without exposing the sample to the outer environment. This may enable greater sample retention during sample processing and centrifugation of the sample. |
| FILED | Tuesday, January 11, 2022 |
| APPL NO | 17/573311 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5021 (20130101) Original (OR) Class B01L 3/502715 (20130101) B01L 2200/10 (20130101) B01L 2300/087 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230219304 | Roy |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of The University of Alabama (Tuscaloosa, Alabama) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Samit Roy (Northport, Alabama) |
| ABSTRACT | Disclosed herein are methods for designing composite materials with improved toughness. |
| FILED | Thursday, November 10, 2022 |
| APPL NO | 17/984335 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 70/04 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2101/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/005 (20130101) C08J 5/041 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230219699 | Helvajian et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Henry Helvajian (Pasadena, California); Randy Villahermosa (La Canada Flintridge, California) |
| ABSTRACT | Cell-based systems may interlock in a reconfigurable configuration to support a mission. Space systems, for example, of a relatively large size may be assembled using an ensemble of individual “cells”, which are individual space vehicles. The cells may be held together via magnets, electromagnets, mechanical interlocks, etc. The topology or shape of the joined cells may be altered by cells hopping, rotating, or “rolling” along the joint ensemble. The cells may be multifunctional, mass producible units. Rotation of cell faces, or of components within cells, may change the functionality of the cell. The cell maybe collapsible for stowage or during launch. |
| FILED | Friday, March 17, 2023 |
| APPL NO | 18/185709 |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/244 (20190501) B64G 1/283 (20130101) Original (OR) Class B64G 1/443 (20130101) B64G 1/645 (20130101) B64G 1/646 (20130101) B64G 1/1085 (20130101) B64G 2001/1092 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220011 | Gao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xiaojing Gao (Los Angeles, California); Michael B. Elowitz (Los Angeles, California) |
| ABSTRACT | Disclosed herein include methods, compositions, and kits suitable for use in detecting the activation level of a signal transducer. In some embodiments, there are provided synthetic protein circuits wherein recruitment of synthetic protein circuit components to an association location upon activation of a signal transducer generates an active effector protein. The effector protein can be configured to carry out a variety of functions when in an active state, such as, for example, inducing cell death. Methods of treating a disease or disorder characterized by aberrant signaling are provided in some embodiments. |
| FILED | Wednesday, December 14, 2022 |
| APPL NO | 18/065880 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/001 (20130101) Original (OR) Class C07K 14/47 (20130101) C07K 2319/02 (20130101) C07K 2319/50 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/506 (20130101) Enzymes C12Y 304/22044 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6803 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220016 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Monsanto Company (St. Louis, Missouri) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Monsanto Company (St. Louis, Missouri) |
| INVENTOR(S) | David R. Liu (Cambridge, Massachusetts); Ahmed Hussein Badran (Cambridge, Massachusetts); Victor Guzov (Cambridge, Massachusetts); Tom Malvar (North Stonington, Connecticut); Prashanth Vishwanath (Arlington, Massachusetts); Jeff Nageotte (Billerica, Massachusetts); Qing Huai (Winchester, Massachusetts); Melissa Kemp (Medford, Massachusetts) |
| ABSTRACT | The disclosure provides amino acid sequence variants of Bacillus thuringiensis (Bt) toxins and methods of producing the same. Some aspects of this disclosure provide methods for generating Bt toxin variants by continuous directed evolution. Some aspects of this disclosure provide compositions and methods for pest control using the disclosed variant Bt toxins. |
| FILED | Wednesday, October 26, 2022 |
| APPL NO | 18/050014 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/50 (20200101) Peptides C07K 14/325 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1058 (20130101) C12N 15/8286 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220401 | SIERKS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael SIERKS (Fort McDowell, Arizona); Lalitha VENKATARAMAN (Tempe, Arizona); Wei XIN (Tempe, Arizona) |
| ABSTRACT | The present invention provides detection reagents and method for determining risk of traumatic brain injury (TBI) and/or susceptibility to neurodegenerative disease in a subject. |
| FILED | Tuesday, December 20, 2022 |
| APPL NO | 18/085418 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Peptides C07K 1/22 (20130101) C07K 16/18 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) G01N 2800/2821 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220438 | Lynch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Michael David Lynch (Durham, North Carolina); Romel Menacho Melgar (Durham, North Carolina); Eirik Adim Moreb (Durham, North Carolina); John P. Efromson (Durham, North Carolina) |
| ABSTRACT | An improved strain of E. coli for autoinduction of protein expression but also of autolytic enzymes thereby enabling combined autolysis and auto DNA/RNA hydrolysis. This combination of these two mechanisms improves cellular lysis and DNA removal and expounds the benefits of two stage production of a protein product. This system enables greater than 95% lysis and hydrolysis due to tightly controlled expression the genes. The autolytic genes may encode a lysozyme and a benzonase. |
| FILED | Friday, January 08, 2021 |
| APPL NO | 17/758477 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/06 (20130101) C12N 9/16 (20130101) C12N 9/2462 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) Original (OR) Class Enzymes C12Y 301/30002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220442 | Xu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Ting Xu (Berkeley, California); Brian Panganiban (Berkeley, California); Tao Jiang (Berkeley, California) |
| ABSTRACT | Compositions comprise statistically random heteropolymers complexed with active proteins, and are formulated and used in stimuli-responsive materials and nanoreactors composed of proteins and synthetic materials. |
| FILED | Saturday, March 04, 2023 |
| APPL NO | 18/178505 |
| CURRENT CPC | Compositions of Macromolecular Compounds C08L 89/00 (20130101) C08L 2203/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/34 (20130101) Original (OR) Class Enzymes C12Y 301/08001 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220999 | Turney et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Joseph Turney (Amston, Connecticut); Christopher Britton Greene (Hebron, Connecticut); Peter AT Cocks (South Glastonbury, Connecticut); Andrzej Ernest Kuczek (Bristol, Connecticut); James M. Donohue (Glastonbury, Connecticut) |
| ABSTRACT | A combustor for a detonation engine includes a radially outer wall extending along an axis; a radially inner wall extending along the axis, wherein the radially inner wall is positioned at least partially within the radially outer wall to define an annular detonation chamber having an inlet for fuel and oxidant and an outlet; a cooling flow passage defined along at least one of the radially outer wall and the radially inner wall and comprising at least two axially spaced cooling flow passage sections, whereby a different cooling rate can be implemented in the at least two axially spaced cooling flow passage sections. |
| FILED | Friday, April 09, 2021 |
| APPL NO | 17/226444 |
| CURRENT CPC | Jet-propulsion Plants F02K 7/02 (20130101) Original (OR) Class Methods or apparatus for combustion using fluid fuel or Solid Fuel Suspended In Air F23C 15/00 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) F23R 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230221229 | ZANOTTO et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey) |
| INVENTOR(S) | Damiano ZANOTTO (Jersey City, New Jersey); Ton DUONG (Glen Ridge, New Jersey) |
| ABSTRACT | A sensor apparatus for footwear includes at least one pair of light sources and at least one pair of light receivers, each light receiver being positioned and configured to receive light emitted from a respective one of the light sources. A pair of movable curtains functions to adjust the amount of light received by the pair of light receivers. The curtains are movable conjointly such that the amount of light received by one of the light receivers is inversely proportional to the amount of light received by the other light receiver. (FIG. 1B). |
| FILED | Friday, May 28, 2021 |
| APPL NO | 17/928229 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/112 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/24 (20130101) Original (OR) Class G01N 2203/0025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230221242 | Caldwell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee); Third Floor Materials, Inc. (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joshua D. Caldwell (Nashville, Tennessee); Edward Sachet (Nashville, Tennessee); Christopher Shelton (Nashville, Tennessee); Thomas G. Folland (Nashville, Tennessee) |
| ABSTRACT | Devices and methods for non-dispersive infrared (NDIR) sensing are disclosed. In one aspect, a non-dispersive infrared sensor is disclosed which, in one embodiment includes a nanophotonic infrared emitting metamaterial (NIREM) emitter configured to selectively emit radiation corresponding to a respective vibrational resonance frequency for each of a plurality of different analytes of interest. The broadband detector can be configured to detect photons associated with vibrational resonance of each of the plurality of analytes of interest in response to the emitted radiation from the NIREM emitter, in order to determine properties of one or more of the analytes of interest. |
| FILED | Thursday, January 12, 2023 |
| APPL NO | 18/096319 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/1702 (20130101) Original (OR) Class G01N 33/0027 (20130101) G01N 2021/1704 (20130101) G01N 2201/061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230221247 | Huffman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tyler Huffman (Alexandria, Virginia); Robert Furstenberg (Burke, Virginia); Chris Kendziora (Burke, Virginia); R. Andrew McGill (Lorton, Virginia) |
| ABSTRACT | The present invention provides a method for spectroscopic imaging by illuminating a sample with a short infrared pulse, directing one or more probe beams to the sample, and measuring light that is reflected, transmitted, or re-emitted inelastically, where a spectrum is collocated by varying the wavelength of the infrared pulse and an image is collected by moving the sample and probe beam relative to each other as the steps are repeated multiple times to create a multidimensional spectroscopic image of the sample. Also disclosed are the related methods for analyzing the data and the related system for spectroscopic imaging. |
| FILED | Thursday, January 12, 2023 |
| APPL NO | 18/096250 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/3563 (20130101) Original (OR) Class G01N 2201/0636 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230221780 | Reed et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher Reed (McKinney, Texas); James Ruiz (McKinney, Texas) |
| ABSTRACT | Disclosed herein is a computer circuit card cage system configured to house one or more computer circuit cards. The computer circuit card cage system can comprise a housing comprising one or more walls having one or more apertures formed therein. The computer circuit card cage system can further comprise one or more support rails supported on one or more of the walls and configured to support a computer circuit card. The one or more support rails can have one or more apertures formed therein to facilitate flow of a fluid through the one or more support rails. The flow path of the fluid is through the one or more apertures in the walls of the housing, and the one or more apertures in the support rails. |
| FILED | Tuesday, January 11, 2022 |
| APPL NO | 17/573464 |
| CURRENT CPC | Electric Digital Data Processing G06F 1/20 (20130101) Original (OR) Class G06F 1/183 (20130101) G06F 2200/201 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/1424 (20130101) H05K 7/20136 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230222274 | Kehlet et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | David Kehlet (Los Altos Hills, California); Nij Dorairaj (Campbell, California) |
| ABSTRACT | A computer system is provided for protecting a circuit design for an application specific integrated circuit. The computer system includes a logic circuit replacement tool for identifying a module of logic circuitry for replacement in at least a portion of the circuit design. The logic circuit replacement tool generates a transformed circuit design for the application specific integrated circuit by replacing the logic circuitry in the module with a configurable circuit that performs a logic function of the logic circuitry when a bitstream stored in storage circuits in the configurable circuit configures the configurable circuit. The transformed circuit design includes the configurable circuit in the module. |
| FILED | Tuesday, March 21, 2023 |
| APPL NO | 18/124259 |
| CURRENT CPC | Electric Digital Data Processing G06F 30/323 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230222303 | Burnett |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | US Gov't as represented by Sec'y of Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gregory M. Burnett (Dayton, Ohio) |
| ABSTRACT | A method and apparatus to control optical communication between proximal devices, providing autonomous data transfer sessions that include optically-represented datagram (e.g., QR Code™) presentations, is disclosed. Optical control signals sent between a viewing device and a presenting device enable control of the presenting device without physical contact during initiation, performance, and termination of the transfer session. Advancement between datagrams is provided by control signals indicated by changes in relative orientation, changes in relative position, and gestural relative motion between the proximal devices. |
| FILED | Monday, January 10, 2022 |
| APPL NO | 17/571598 |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/1408 (20130101) Original (OR) Class G06K 7/10821 (20130101) Wireless Communication Networks H04W 4/80 (20180201) H04W 76/14 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230222654 | Fan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SPECTRAL MD, INC. (Dallas, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Wensheng Fan (Plano, Texas); John Michael DiMaio (Dallas, Texas); Jeffrey E. Thatcher (Irving, Texas); Peiran Quan (Dallas, Texas); Faliu Yi (Allen, Texas); Kevin Plant (Dallas, Texas); Ronald Baxter (Grand Prairie, Texas); Brian McCall (Dallas, Texas); Zhicun Gao (Plano, Texas); Jason Dwight (Dallas, Texas) |
| ABSTRACT | Machine learning systems and methods are disclosed for prediction of wound healing, such as for diabetic foot ulcers or other wounds, and for assessment implementations such as segmentation of images into wound regions and non-wound regions. Systems for assessing or predicting wound healing can include a light detection element configured to collect light of at least a first wavelength reflected from a tissue region including a wound, and one or more processors configured to generate an image based on a signal from the light detection element having pixels depicting the tissue region, determine reflectance intensity values for at least a subset of the pixels, determine one or more quantitative features of the subset of the plurality of pixels based on the reflectance intensity values, and generate a predicted or assessed healing parameter associated with the wound over a predetermined time interval. |
| FILED | Thursday, March 02, 2023 |
| APPL NO | 18/177493 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0077 (20130101) A61B 5/445 (20130101) A61B 5/7275 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 2207/20081 (20130101) G06T 2207/30088 (20130101) G06T 2207/30096 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230222927 | GOBIN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (Blacksburg, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bradley Scott GOBIN (Carlisle, Pennsylvania); Robert Clayton BRIGGS (Blacksburg, Virginia); Thomas JONES (Blacksburg, Virginia); Robert A. CANFIELD (Blacksburg, Virginia) |
| ABSTRACT | Various embodiments of a system and method for a quantitative approach and departure risk assessment are described. In one example, the system includes program instructions executable in the computing device that, when executed by the computing device, cause the computing device to: obtain a nominal flight path of an aircraft, calculate a potential crash area for a section of the nominal flight path based on a failure mode, calculate risk values based on a population data of a geographical area traveled corresponding to the nominal flight path, and display the calculated risk values plotted on a map of at least a section of the geographical area traveled corresponding to the nominal flight path. Other examples include corresponding computer systems, apparatus, and computer programs recorded on one or more computer storage devices, each configured to perform the actions of the methods. |
| FILED | Tuesday, July 20, 2021 |
| APPL NO | 18/000730 |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/20 (20130101) Traffic Control Systems G08G 5/003 (20130101) G08G 5/0056 (20130101) Original (OR) Class G08G 5/0069 (20130101) G08G 5/0091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230223324 | Stadler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bethanie J Stadler (Shoreview, Minnesota); Rhonda R. Franklin (Falcon Heights, Minnesota) |
| ABSTRACT | A device includes a porous substrate that include a plurality of pores and a plurality of nanodevices dispersed in at least a portion of the plurality of pores. Each of the plurality of nanodevices includes a magnetic nanowire and a solder nanoparticle. The magnetic nanowires are configured to generate heat in response to an alternating magnetic field. The solder nanoparticles are configured to receive a portion of the heat and reflow to connect to one or more devices or surfaces. |
| FILED | Friday, January 06, 2023 |
| APPL NO | 18/151250 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/486 (20130101) H01L 23/5384 (20130101) H01L 23/49827 (20130101) Original (OR) Class H01L 24/13 (20130101) H01L 24/16 (20130101) H01L 24/81 (20130101) H01L 2224/1312 (20130101) H01L 2224/13109 (20130101) H01L 2224/13111 (20130101) H01L 2224/13118 (20130101) H01L 2224/13138 (20130101) H01L 2224/13139 (20130101) H01L 2224/13147 (20130101) H01L 2224/16235 (20130101) H01L 2224/81192 (20130101) H01L 2224/81222 (20130101) H01L 2224/81815 (20130101) H01L 2924/01014 (20130101) Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 12/52 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/145 (20130101) H05K 1/181 (20130101) H05K 3/0014 (20130101) H05K 3/368 (20130101) H05K 3/424 (20130101) H05K 3/3436 (20130101) H05K 3/3494 (20130101) H05K 2201/10378 (20130101) H05K 2203/0723 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230223463 | Holt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GlobalFoundries U.S. Inc. (Malta, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Judson R. Holt (Ballston Lake, New York); Vibhor Jain (Clifton Park, New York); Jeffrey B. Johnson (Essex Junction, Vermont); John J. Pekarik (Underhill, Vermont) |
| ABSTRACT | Embodiments of the disclosure provide a bipolar transistor structure with a collector on a polycrystalline isolation layer. A polycrystalline isolation layer may be on a substrate, and a collector layer may be on the polycrystalline isolation layer. The collector layer has a first doping type and includes a polycrystalline semiconductor. A base layer is on the collector layer and has a second doping type opposite the first doping type. An emitter layer is on the base layer and has the first doping type. A material composition of the doped collector region is different from a material composition of the base layer. |
| FILED | Thursday, January 13, 2022 |
| APPL NO | 17/574661 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/763 (20130101) H01L 29/0642 (20130101) H01L 29/7371 (20130101) Original (OR) Class H01L 29/66242 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230223514 | DeBlock et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Ryan H. DeBlock (Alexandria, Virginia); Joseph F. Parker (Riva, Maryland); Jeffrey W. Long (Alexandria, Virginia); Debra R. Rolison (Arlington, Virginia); Christopher N. Chervin (Washington, District of Columbia) |
| ABSTRACT | A method of: placing a mixture of zinc particles; water; a water-soluble thickener; and water-insoluble inorganic porogen particles into a mold; evaporating the water to form a monolith; heating the monolith to fuse the zinc particles together; and submerging the monolith in a liquid that removes the porogen particles. A method of: placing a mixture of zinc particles; an aqueous acetic acid solution; and porogen particles into a mold; evaporating water to form a monolith; and submerging the monolith in a liquid that removes the porogen particles. |
| FILED | Friday, January 13, 2023 |
| APPL NO | 18/154078 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/244 (20130101) Original (OR) Class H01M 4/0433 (20130101) H01M 4/0471 (20130101) H01M 2004/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230223595 | Ma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Army DEVCOM, Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lin Ma (Silver Spring, Maryland); Marshall A. Schroeder (Pasadena, Maryland); Oleg A. Borodin (Laurel, Maryland); Travis P. Pollard (Rockville, Maryland); Kang Xu (Potomac, Maryland) |
| ABSTRACT | An electrochemical cell (such as a battery) that provides, inter alia, improved cycling efficiencies, by utilizing an electrolyte and a plurality of electrodes (including at least one metal electrode) where the electrolyte includes one or more solvents, one or more salts, and one or more additives, and at least one of the additives is a heterocyclic compound. |
| FILED | Tuesday, January 11, 2022 |
| APPL NO | 17/573178 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0567 (20130101) Original (OR) Class H01M 2300/0025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230223741 | Jiang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Texas Tech University System (Lubbock, Texas) |
| ASSIGNEE(S) | TEXAS TECH UNIVERSITY SYSTEM (Lubbock, Texas) |
| INVENTOR(S) | Hongxing Jiang (Lubbock, Texas); Zhenyu Sun (Lubbock, Texas); Yaqiong Yan (Lubbock, Texas); Jing Li (Lubbock, Texas); Jingyu Lin (Lubbock, Texas) |
| ABSTRACT | Core-cladding planar waveguide (PWG) structures and methods of making and using same. The core-cladding PWG structures can be synthesized by hydride vapor phase epitaxy and processed by mechanical and chemical-mechanical polishing. An Er doping concentration of [Er] between 1×1018 atoms/cm3 and 1×1022 atoms/cm3 can be in the core layer. Such PWGs have a core region that can achieve optical confinement between 96% and 99% and above. |
| FILED | Thursday, March 12, 2020 |
| APPL NO | 17/439321 |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0632 (20130101) H01S 5/0265 (20130101) H01S 5/2214 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230224018 | Anderson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Govt of the US as rep by the Secy of the Air Force (Wright Patterson AFB, Ohio) |
| ASSIGNEE(S) | Government of the United States as represented by the Secretary of the Air Force (Wright Patterson AFB, Ohio) |
| INVENTOR(S) | Michael L. Anderson (Colorado Springs, Colorado); Nicholas R. Black (Charlotte, North Carolina); Joseph A. Puglisi (Roy, Utah); Mary E. Hood (Brighton, United Kingdom); Joseph Anderson (Edwards, California) |
| ABSTRACT | A portable communication system for use in hostile and unknown environments. The system has a base station for control by an operator. The base station dispatches one or more unmanned drones into the hostile environment, where a forward agent, such a robot or investigative person can approach a suspected threat. Each drone has a payload of repeaters to be delivered as necessary to maintain line of sight communication from the forward agent back to the base station. Once delivered, the repeaters are mobile and can autonomously reposition to maintain or optimize line of sight communication. Communications from the forward agent back to the base station are then interpreted and analyzed for further action. |
| FILED | Wednesday, February 09, 2022 |
| APPL NO | 17/667824 |
| CURRENT CPC | Transmission H04B 7/15507 (20130101) Original (OR) Class H04B 7/18504 (20130101) Wireless Communication Networks H04W 4/44 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230224020 | Flint et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Spencer Flint (Seattle, Washington); Erin Leslie (Oklahoma City, Oklahoma); Nathaniel Bowen (Columbus, Mississippi); Michael Anderson (Colorado Springs, Colorado) |
| ABSTRACT | A communication system for sending surveillance signals in a hostile environment to an operator. The communication system comprises a plurality of relay sensors to transceive collected data between sequential relay sensors and ultimately to an operator. The communication system has a tractor for dispensing plural relay sensors throughout the hostile environment. The sensors may be dispensed by an elevator to a position where a relay sensor can be retrieved by a drone for placement to maintain line of sight communication. And relay sensors can be dispensed directly from the tractor to the ground or water. Direct dispensing of the relay sensors can occur through a hole in tractor or off a ramp. |
| FILED | Friday, September 30, 2022 |
| APPL NO | 17/936964 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) Unmanned aerial vehicles [UAV]; equipment therefor B64U 70/90 (20230101) B64U 2101/60 (20230101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0022 (20130101) Transmission H04B 7/18504 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230224037 | Burnett |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | US Gov't as represented by Sec'y of Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gregory M. Burnett (Dayton, Ohio) |
| ABSTRACT | A method and apparatus to control optical communication between proximal devices, providing autonomous data transfer sessions that include optically-represented datagram (e.g., QR code™) presentations, is disclosed. Optical control signals sent between a viewing device and a presenting device enable control of the presenting device without physical contact during initiation, performance, and termination of the transfer session. Advancement between datagrams is provided by control signals indicated by changes in relative orientation, changes in relative position, and gestural relative motion between the proximal devices. |
| FILED | Monday, January 10, 2022 |
| APPL NO | 17/571591 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/14 (20130101) G06F 3/017 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/1417 (20130101) Image Data Processing or Generation, in General G06T 7/70 (20170101) G06T 2207/10016 (20130101) Transmission H04B 10/1143 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230224199 | Swanson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Naval Information Warfare Center Pacific (San Diego, California) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (San Diego, California) |
| INVENTOR(S) | Paul David Swanson (Santee, California) |
| ABSTRACT | A method for demodulating an RF signal to polar in-phase and quadrature (IQ) components that includes converting an RF signal with an analog-to-digital converter and calculating the polar in-phase and quadrature (IQ) components of the RF signal as an IQ phasor phase angle and an IQ amplitude using a digital processor. The analog-to-digital converter uses a sampling rate, where, when the sampling rate used has sampling rates other than 3 times an RF carrier frequency of the RF signal, a digital logic circuit splines data to the sampling rate of 3 times the RF carrier frequency of the RF signal. The digital processor calculates the polar in-phase and quadrature (IQ) components of the RF signal as an IQ phasor phase angle and an IQ amplitude using addition, subtraction, multiplication, division, and absolute value. |
| FILED | Wednesday, January 12, 2022 |
| APPL NO | 17/574319 |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 1/124 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230225225 | YANG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Yu-Tao YANG (Los Angeles, California); Subramanian S. IYER (Los Angeles, California) |
| ABSTRACT | Example implementations include a method of manufacturing a quantum computing device, by depositing a superconducting electrode layer on at least a portion of a superconducting wafer, forming a plurality of electrode pads on the superconducting electrode layer, depositing an electrode bonding interlayer on the electrode pads, singulating the superconducting wafer into a first superconducting die including a first electrode pad among the plurality and a second superconducting die including a second electrode pad among the plurality, and integrating the first superconducting die with the second superconducting die at a bonding interface between the first electrode pad and the second electrode pad. |
| FILED | Thursday, May 27, 2021 |
| APPL NO | 18/000377 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/40 (20220101) Electric solid-state devices not otherwise provided for H10N 69/00 (20230201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20230219058 | Campbell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Patrick Campbell (Oakland, California); Sarah Baker (Dublin, California); Maira R. Ceron Hernandez (Brentwood, California); Jennifer Marie Knipe (Oakland, California); Joshuah K. Stolaroff (Oakland, California) |
| ABSTRACT | An ink for three dimensional printing a ceramic material includes metal oxide nanoparticles and a polymer resin, where a concentration of the metal oxide nanoparticles is at least about 50 wt % of a total mass of the ink. A method of forming a porous ceramic material includes obtaining an ink, where the ink comprises a mixture of metal oxide nanoparticles and a polymer, forming a body from the ink, curing the formed body, heating the formed body for removing the polymer and for forming a porous ceramic material from the metal oxide nanoparticles. The forming the body includes an additive manufacturing process with the ink. |
| FILED | Wednesday, March 22, 2023 |
| APPL NO | 18/124979 |
| CURRENT CPC | Separation B01D 53/62 (20130101) B01D 53/80 (20130101) B01D 53/228 (20130101) B01D 53/229 (20130101) B01D 67/0079 (20130101) B01D 69/141 (20130101) B01D 71/024 (20130101) B01D 2251/304 (20130101) B01D 2251/606 (20130101) B01D 2253/25 (20130101) B01D 2253/202 (20130101) B01D 2253/304 (20130101) B01D 2253/308 (20130101) B01D 2253/1124 (20130101) B01D 2257/504 (20130101) B01D 2259/40088 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/06 (20130101) Original (OR) Class B01J 20/043 (20130101) B01J 20/3007 (20130101) B01J 20/3042 (20130101) B01J 20/3064 (20130101) B01J 20/3078 (20130101) B01J 20/3085 (20130101) B01J 20/3204 (20130101) B01J 20/3287 (20130101) B01J 20/3293 (20130101) B01J 20/3433 (20130101) B01J 20/3483 (20130101) B01J 20/28004 (20130101) B01J 20/28016 (20130101) B01J 20/28083 (20130101) B01J 20/28085 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/10 (20200101) B33Y 80/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230219297 | Moo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho); Addvanced Cooling Technologies, Inc. (Lancaster, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Patrick J. Moo (DeLand, Florida); Michael R. Shaltry (Idaho Falls, Idaho); Donna Post Guillen (Idaho Falls, Idaho); Jeffrey Diebold (Chesterbrook, Pennsylvania); Calin Tarau (Downingtown, Pennsylvania); Kuan-Lin Lee (West Chester, Pennsylvania) |
| ABSTRACT | A heat-transfer device and methods for forming the heat-transfer device are disclosed. The method includes forming a first green structure using digital light processing, the first green structure including a different porosity in at least two sections. The method also includes exposing the first green structure to heat to remove resin used during the digital light processing from the first green structure. The method further includes sintering the first green structure to form at least a portion of the heat-transfer device. |
| FILED | Thursday, January 12, 2023 |
| APPL NO | 18/153886 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/165 (20170801) B29C 64/268 (20170801) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/10 (20200101) B33Y 80/00 (20141201) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/046 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 21/08 (20130101) F28F 21/067 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230219870 | SADOW et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Ames, Iowa); CORNELL UNIVERSITY (Ithaca, New York); UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aaron David SADOW (Ames, Iowa); Uddhav KANBUR (Ames, Iowa); Frederic A. PERRAS (Ames, Iowa); Alexander L. PATERSON (Ames, Iowa); Andrew KOCEN (Brooklyn, New York); Geoffrey W. COATES (Lansing, New York); Anne M. LAPOINTE (Ithaca, New York); Massimiliano DELFERRO (Chicago, Illinois); Ryan A. HACKLER (Chicago, Illinois); Jessica RODRIGUEZ (Ames, Iowa) |
| ABSTRACT | Disclosed herein is the selective functionalization of one or more hydrocarbons ranging from the longest macromolecules to methane as the smallest. Functionalization is achieved through C-H activation of the one or more hydrocarbons and is carried out by the catalytic complex described herein. Also disclosed is the compound of formula (I) and the compound of formula (II). |
| FILED | Tuesday, November 08, 2022 |
| APPL NO | 17/983165 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 29/36 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220121 | ACHINIVU et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ezinne ACHINIVU (Alexandria, Virginia); John M. GLADDEN (Alameda, California); Blake A. SIMMONS (San Francisco, California) |
| ABSTRACT | The present invention provides for a method to produce a sugar compound from a biomass, the method comprising: (a) providing a first mixture comprising a solubilized biomass and an alkanolamine; (b) recovering at least part of the alkanolamine from the first mixture in order to separate the at least part of the alkanolamine from the first mixture; (c) optionally introducing an enzyme and/or a microbe to the first mixture such that the enzyme and/or microbe produce a sugar from the solubilized biomass; and, (d) optionally the sugar is separated from the first mixture. |
| FILED | Thursday, April 29, 2021 |
| APPL NO | 17/925266 |
| CURRENT CPC | Polysaccharides; Derivatives Thereof C08B 37/0003 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220158 | Dishari |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shudipto Konika Dishari (Dhaka, Bangladesh) |
| ABSTRACT | Provided here are ion conducting materials including one or more macrocycles, and either one or more pendant groups or one or more backbone repeat units. The ion conducting materials exhibit distinctly high ion conductivity in thin film and bulk membrane applications, and further exhibit one or more of ion permselectivity, mechanical strength, self-assembly, stacking, and gating behavior. Further provided are methods for preparation and methods for use of the ion conducting materials. |
| FILED | Tuesday, April 20, 2021 |
| APPL NO | 17/996666 |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/3346 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/1027 (20130101) H01M 8/1032 (20130101) H01M 10/0565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220434 | LYNCH et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Michael David LYNCH (Durham, North Carolina); Eirik Adim MOREB (Durham, North Carolina); Tian YANG (Durham, North Carolina) |
| ABSTRACT | Methods for CRISPR Enabled DNA Synthesis and compositions arising from the methods are provided. The methods may include ligation of partially single stranded DNA donor and acceptor oligonucleotides that are covalently linked to a subsequence of the target DNA to be sequenced followed by cleavage of the ligated product. In this manner the donor and acceptor oligonucleotides shuttle a growing subsequence of the target DNA with each cycle. A mutant Cpfl nuclease is missing non-specific ssDNA nuclease activity may be used for cleavage of the ligation product. Fourteen ligation/cleavage cycles can result in synthesis of ssDNA of greater than 10,000 bp in length. |
| FILED | Friday, January 08, 2021 |
| APPL NO | 17/758480 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 2310/20 (20170501) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6844 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220438 | Lynch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Michael David Lynch (Durham, North Carolina); Romel Menacho Melgar (Durham, North Carolina); Eirik Adim Moreb (Durham, North Carolina); John P. Efromson (Durham, North Carolina) |
| ABSTRACT | An improved strain of E. coli for autoinduction of protein expression but also of autolytic enzymes thereby enabling combined autolysis and auto DNA/RNA hydrolysis. This combination of these two mechanisms improves cellular lysis and DNA removal and expounds the benefits of two stage production of a protein product. This system enables greater than 95% lysis and hydrolysis due to tightly controlled expression the genes. The autolytic genes may encode a lysozyme and a benzonase. |
| FILED | Friday, January 08, 2021 |
| APPL NO | 17/758477 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/06 (20130101) C12N 9/16 (20130101) C12N 9/2462 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) Original (OR) Class Enzymes C12Y 301/30002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220943 | Duncan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexander Kyle Duncan (Niskayuna, New York); Todd William Danko (Niskayuna, New York) |
| ABSTRACT | A system for use in maintaining a structure includes a maintenance apparatus including a maintenance drive system and a maintenance device. The system includes a support apparatus configured to travel in proximity to the structure. The support apparatus includes a body including a first end and a second end and a tether support device coupled to the body. The tether support device includes a housing. The support apparatus also includes a support drive system coupled to the body. The support drive system is configured to propel the support apparatus. The system also includes a tether including a first tether end, a second tether end, and a tether body extending between the first tether end and the second tether end. The maintenance apparatus is operably coupled to the first tether end. The tether support device is coupled to the tether between the first tether end and the second tether end. |
| FILED | Monday, January 10, 2022 |
| APPL NO | 17/572312 |
| CURRENT CPC | Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 55/30 (20130101) Original (OR) Class F16L 55/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230221040 | Ho et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Clifford K. Ho (Albuquerque, New Mexico); Kevin Albrecht (Albuquerque, New Mexico) |
| ABSTRACT | The present disclosure is directed to systems and methods to control particle mass flow rate in solar receivers and associated heat exchangers based on feedback from one or more temperatures of particles in the system. |
| FILED | Monday, March 06, 2023 |
| APPL NO | 18/117932 |
| CURRENT CPC | Solar Heat Collectors; Solar Heat Systems F24S 20/20 (20180501) Original (OR) Class F24S 50/40 (20180501) F24S 80/00 (20180501) F24S 80/20 (20180501) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230221219 | Thorpe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Bridger Photonics, Inc. (Bozeman, Montana) |
| ASSIGNEE(S) | Bridger Photonics, Inc. (Bozeman, Montana) |
| INVENTOR(S) | Michael James Thorpe (Bozeman, Montana); Aaron Thomas Kreitinger (Bozeman, Montana) |
| ABSTRACT | Apparatuses systems and methods for gas emission rate detection sensitivity and probability of detection (PoD) based on emission rate. A measurement system may be characterized by its ability to detect gas plumes as a function of the emission rate of those plumes. The measurement system may be characterized based on a generalized PoD function which expresses PoD relative to emission rate as a function of gas concentration noise and gas flow speed. In an example application, the PoD may be used to estimate a cumulative distribution of gas plumes which were not detected based on a cumulative distribution of measured gas plumes. In another example application, the PoD may be used to refine an estimate for a measured emission rate. |
| FILED | Thursday, November 10, 2022 |
| APPL NO | 18/054517 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/2247 (20130101) Original (OR) Class G01N 15/0612 (20130101) G01N 21/8851 (20130101) G01N 2021/8887 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230221285 | Dou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Liminal Insights, Inc. (Emeryville, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shan Dou (Berkeley, California); Andrew G. Hsieh (Berkeley, California); Shaurjo Biswas (El Cerrito, California); Barry J. Van Tassell (El Cerrito, California); Elizabeth M. Lee (Oakland, California); Dennis Yu (Berkeley, California); Jason Y. Yu (Emeryville, California) |
| ABSTRACT | Systems and techniques for measuring process characteristics including electrolyte distribution in a battery cell. A non-destructive method for analyzing a battery cell includes determining acoustic features at two or more locations of the battery cell, the acoustic features based on one or more of acoustic signals travelling through at least one or more portions of the battery cell during one or more points in time or responses to the acoustic signals obtained during one or more points in time, wherein the one or more points in time correspond to one or more stages of electrolyte distribution in the battery cell. One or more characteristics of the battery cell are determined based on the acoustic features at the two or more locations of the battery cell. |
| FILED | Monday, March 06, 2023 |
| APPL NO | 18/117815 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/0654 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/484 (20130101) H01M 50/60 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230221306 | LAWRENCE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BATTELLE SAVANNAH RIVER ALLIANCE, LLC (AIKEN, South Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | KAITLIN LAWRENCE (AIKEN, South Carolina); STEVEN DEMERS (AIKEN, South Carolina); WENDY KUHNE (EVANS, Georgia); ASHLEE R. SWINDLE (AIKEN, South Carolina) |
| ABSTRACT | A multifunctional biosensor is described that is configured to simultaneously detect two or more different types of chemical, biological and/or radiological/nuclear (CBRN) threats on one platform using FRET-based and/or NSET-based technology. |
| FILED | Tuesday, October 18, 2022 |
| APPL NO | 17/968446 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6818 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/77 (20130101) G01N 21/6428 (20130101) G01N 33/542 (20130101) Original (OR) Class G01N 2021/7786 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 5/0075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230221455 | Walsh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vista Clara Inc. (Mukilteo, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Walsh (Shoreline, Washington); Elliot Grunewald (Seattle, Washington) |
| ABSTRACT | Circuits that employ selective solid-state isolation of circuit elements can include solid-state switches, such as back-to-back Field Effect Transistor (FET) pairs, and isolated gate drive electronics adapted to operate the solid-state switches in order to selectively decouple certain circuit elements. The isolated solid-state switches can be placed in series to achieve higher standoff voltages, and can be configured for low on resistance and short switching times. The gate drive electronics can include electrical isolation components adapted to enhance standoff voltages and reduce electrical noise at the selectively isolated circuit elements. |
| FILED | Thursday, January 13, 2022 |
| APPL NO | 17/647876 |
| CURRENT CPC | Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 3/14 (20130101) Original (OR) Class G01V 3/38 (20130101) Pulse Technique H03K 17/6874 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230221458 | Labov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Simon E. Labov (Berkeley, California); Karl E. Nelson (Livermore, California); Brandon S. Seilhan (Emeryville, California) |
| ABSTRACT | A system identifying a source of radiation is provided. The system includes a radiation source detector and a radiation source identifier. The radiation source detector receives measurements of radiation; for one or more sources, generates a detection metric indicating whether that source is present in the measurements; and evaluates the detection metrics to detect whether a source is present in the measurements. When the presence of a source in the measurements is detected, the radiation source identifier for one or more sources, generates an identification metric indicating whether that source is present in the measurements; generates a null-hypothesis metric indicating whether no source is present in the measurements; evaluates the one or more identification metrics and the null-hypothesis metric to identify the source, if any, that is present in the measurements. |
| FILED | Tuesday, October 25, 2022 |
| APPL NO | 17/972761 |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/36 (20130101) G01T 1/167 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 5/0075 (20130101) Original (OR) Class G01V 5/0091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230222058 | Sheridan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Patrick Michael Sheridan (Boulder, Colorado) |
| ABSTRACT | Disclosed in some examples are methods, systems, memory devices, memory controllers, and machine-readable mediums which provide for reserving physical memory device resources to specific execution units. Execution units may include processes, threads, virtual machines, functions, procedures, or the like. Physical memory device resources may include channels, modules, ranks, banks, bank groups, and the like. For example, a physical memory device resource that is reservable may be a smallest unit that allows for parallel access with another of the same size unit. |
| FILED | Friday, November 04, 2022 |
| APPL NO | 17/980919 |
| CURRENT CPC | Electric Digital Data Processing G06F 12/0238 (20130101) G06F 12/0638 (20130101) Original (OR) Class G06F 13/1668 (20130101) G06F 2212/7201 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230223158 | SHUMLAK et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Uri SHUMLAK (Seattle, Washington); Brian A. NELSON (Seattle, Washington); Raymond GOLINGO (Seattle, Washington) |
| ABSTRACT | An example method includes directing gas, via one or more first valves, from within an inner electrode to an acceleration region between the inner electrode and an outer electrode that substantially surrounds the inner electrode, directing gas, via two or more second valves, from outside the outer electrode to the acceleration region, and applying, via a power supply, a voltage between the inner electrode and the outer electrode, thereby converting at least a portion of the directed gas into a plasma having a substantially annular cross section, the plasma flowing axially within the acceleration region toward a first end of the inner electrode and a first end of the outer electrode and, thereafter, establishing a Z-pinch plasma that flows between the first end of the outer electrode and the first end of the inner electrode. Related plasma confinement systems and methods are also disclosed herein. |
| FILED | Thursday, January 05, 2023 |
| APPL NO | 18/150255 |
| CURRENT CPC | Fusion Reactors G21B 1/05 (20130101) Original (OR) Class Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/04 (20130101) H05H 1/06 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230223273 | Shul et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology & Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Randy J. Shul (Baltimore, Maryland); Caitlin Rochford Friedman (Albuquerque, New Mexico); Gregory Paul Salazar (Rio Rancho, New Mexico); Michael J. Rye (Albuquerque, New Mexico); John Mudrick (Albuquerque, New Mexico); Craig Y. Nakakura (Corrales, New Mexico); Jeffry Joseph Sniegowski (Tijeras, New Mexico); Karl Douglas Greth (Albuquerque, New Mexico) |
| ABSTRACT | The present invention relates to methods of delayering a semiconductor integrated circuit die or wafer. In at least one aspect, the method includes exposing a die or wafer to plasma of an etching gas and detecting exposure of one or more metal layers within the die. In one aspect of the invention, the plasma of the etching gas is non-selective and removes all materials in a layer at about the same rate. In another aspect of the invention, two different plasmas of corresponding etching gases are employed with each plasma of the etching gas being selective, thus necessitating the sequential use of both plasmas of corresponding etching gases to remove all materials in a layer. |
| FILED | Tuesday, February 14, 2023 |
| APPL NO | 18/109651 |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/321 (20130101) Original (OR) Class H01J 2237/3341 (20130101) H01J 2237/3346 (20130101) H01J 2237/24585 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/31116 (20130101) H01L 21/32136 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230223484 | Zhao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hongping Zhao (Columbus, Ohio); Kaitian Zhang (Columbus, Ohio) |
| ABSTRACT | Disclosed herein are photonic materials. The photonic materials comprise a first layer, a second layer, and a third layer, wherein the second layer is disposed between and in contact with the first layer and the third layer, such that the second layer is sandwiched between the first layer and the third layer. In some examples, the first layer comprises InyGa1-yN, wherein y is from 0 to 0.8. In some examples, the second layer comprises (ZnaSnbGec)xGadN2, wherein: x is from greater than 0 to 1; a, b, c, and d are each independently from 0 to 1; with the proviso that at least one of a, b, or c is greater than 0. In some examples, the third layer comprises InzGa1-zN, wherein z is from 0 to 0.8. |
| FILED | Thursday, November 10, 2022 |
| APPL NO | 17/984333 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/03048 (20130101) Original (OR) Class H01L 31/035209 (20130101) H01L 33/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230223552 | Ramaswamy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan) |
| ASSIGNEE(S) | GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan) |
| INVENTOR(S) | Nagappan Ramaswamy (Rochester Hills, Michigan); Roland J. Koestner (Rochester Hills, Michigan); Swaminatha P. Kumaraguru (Rochester Hills, Michigan) |
| ABSTRACT | A cathode configured for use within a fuel cell system is provided. The cathode includes a cathode substrate. The cathode further includes a coating disposed upon the cathode substrate and including a fluorocarbon polymer additive configured for sintering at a temperature of less than 200° C. The fluorocarbon polymer additive may be mixed with a catalyst ink coating or may be applied separately as a topcoat layer. |
| FILED | Tuesday, January 11, 2022 |
| APPL NO | 17/573089 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/8657 (20130101) Original (OR) Class H01M 4/8663 (20130101) H01M 4/8828 (20130101) H01M 4/8885 (20130101) H01M 2004/8689 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230224599 | Gutierrez Barragan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Felipe Gutierrez Barragan (Alameda, California); Yuhao Liu (Madison, Wisconsin); Atul Ingle (Madison, Wisconsin); Mohit Gupta (Madison, Wisconsin); Andreas Velten (Madison, Wisconsin) |
| ABSTRACT | In accordance with some embodiments, systems, methods, and media for high dynamic range imaging using single-photon and conventional image sensor data are provided. In some embodiments, the system comprises: first detectors configured to detect a level of photons proportional to incident photon flux; second detectors configured to detect arrival of individual photons; a processor programmed to: receive, from the first detectors, first values indicative of photon flux from a scene with a first resolution; receive, from the second detectors, second values indicative of photon flux from the scene with a lower resolution; provide a first encoder of a trained machine learning model first flux values based on the first values, provide the second encoder of the model second flux values; receive, as output, values indicative of photon flux from the scene; and generate a high dynamic range image based on the third plurality of values. |
| FILED | Monday, January 10, 2022 |
| APPL NO | 17/572236 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14634 (20130101) H01L 27/14645 (20130101) Pictorial Communication, e.g Television H04N 5/35563 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230225082 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Toyota Motor Engineering and Manufacturing North America, Inc. (Plano, Texas); The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The Regents of the University of California, Merced (Merced, California); Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Toyota Motor Engineering and Manufacturing North America, Inc. (Plano, Texas); The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The Regents of the University of California, Merced (Merced, California); Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Chi Zhang (Palo Alto, California); Qianying Wu (Stanford, California); Muhammad Shattique (Merced, California); Neda Seyedhassantehrani (Merced, California); Souvik Roy (Merced, California); James Palko (Merced, California); Sreekant Narumanchi (Littleton, Colorado); Bidzina Kekelia (Golden, Colorado); Sougata Hazra (Stanford, California); Kenneth E. Goodson (Portola Valley, California); Roman Giglio (Costa Mesa, California); Ercan M. Dede (Ann Arbor, Michigan); Mehdi Asheghi (Oakland, California) |
| ABSTRACT | A cooler device includes a cold plate and a manifold with fluid wicking structure. The cold plate includes an array of bonding posts and an array of fluid channels. Each bonding post of the array of bonding posts has a first height and is in contact with the manifold with fluid wicking structure. Each fluid channel of the array of fluid channels has a second height that is less than the first height. The array of fluid channels include a MIO secondary wick structure. The array of bonding posts is orthogonal to the array of fluid channels. The manifold with fluid wicking structure includes a plurality of spacer elements and a plurality of mesh layers. Each one of the plurality of spacer elements alternate with each one of the plurality of mesh layers in a stacked arrangement. |
| FILED | Thursday, January 13, 2022 |
| APPL NO | 17/575071 |
| CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20327 (20130101) Original (OR) Class H05K 7/20336 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20230217935 | Yoon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Antithesis Foods Inc. (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Antithesis Foods Inc. (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Ashton Yoon (Philadelphia, Pennsylvania); Jason Goodman (Philadelphia, Pennsylvania); Allie Hall (Philadelphia, Pennsylvania) |
| ABSTRACT | A system and method for the production of doughs and products using textured pulse proteins, including legume-based crunchy snack foods, said method comprising the following steps: homogenization of ingredients in the form of dry feed powders, mixing and hydration of powders with liquid ingredients to form a dough, forming of the dough into form factors, drying and expansion of the form factors to develop texture and shelf stability, and cooling. |
| FILED | Thursday, December 22, 2022 |
| APPL NO | 18/145831 |
| CURRENT CPC | Treatment, e.g Preservation, of Flour or Dough, e.g by Addition of Materials; Baking; Bakery Products; Preservation Thereof A21D 2/266 (20130101) Original (OR) Class A21D 2/362 (20130101) A21D 8/02 (20130101) A21D 10/002 (20130101) A21D 13/06 (20130101) A21D 13/045 (20170101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230218058 | Taig |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RAPHA ROBOTICS INCORPORATED (Lexington, Massachusetts) |
| ASSIGNEE(S) | RAPHA ROBOTICS INCORPORATED (Lexington, Massachusetts) |
| INVENTOR(S) | Elad Taig (Lexington, Massachusetts) |
| ABSTRACT | The present disclosure features systems and devices for robotic debridement and perforating of finger- and toenails, as well as methods of use of the same. The systems and devices may be used for in the treatment of fungal infection of the nail, as well as for cosmetic uses, e.g., pedicure and manicure. |
| FILED | Wednesday, September 15, 2021 |
| APPL NO | 17/615328 |
| CURRENT CPC | Hairdressing or Shaving Equipment; Equipment for Cosmetics or Cosmetic Treatments, e.g for Manicuring or Pedicuring A45D 29/17 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/10 (20130101) A61L 2/24 (20130101) A61L 2202/11 (20130101) A61L 2202/14 (20130101) A61L 2202/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230218435 | Kulstad et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Advanced Cooling Therapy, Inc. (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Erik Kulstad (Dallas, Texas); Hugh Patrick Caherty (Canton, Michigan) |
| ABSTRACT | Relatively non-invasive devices and methods for heating or cooling a patient's body are disclosed. Devices and methods for treating ischemic conditions by inducing therapeutic hypothermia are disclosed. Devices and methods for inducing therapeutic hypothermia through esophageal cooling are disclosed. Devices and methods for operative temperature management are disclosed. |
| FILED | Tuesday, March 14, 2023 |
| APPL NO | 18/183308 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 2017/00084 (20130101) A61B 2090/064 (20160201) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 7/12 (20130101) Original (OR) Class A61F 7/123 (20130101) A61F 2007/0054 (20130101) A61F 2007/0095 (20130101) A61F 2007/126 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230218723 | Ghandehari et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hamidreza Ghandehari (Salt Lake City, Utah); Joseph Cappello (San Diego, California); Azadeh Poursaid (Salt Lake City, Utah); Mark Martin Jensen (Pleasant Grove, Utah) |
| ABSTRACT | Disclosed are methods of treating an aneurysm in a subject comprising administering to the subject a therapeutically effective amount of a composition comprising a SELP. Disclosed are methods of preventing rupture of an aneurysm comprising administering to a subject having an aneurysm a composition comprising a SELP, wherein the SELP is present in the aneurysm and prevents rupture. Also disclosed are methods of embolizing an aneurysm in a subject comprising administering to the subject a therapeutically effective amount of a composition comprising SEEP. Disclosed are methods of treating AVM in a subject comprising administering to the subject a composition comprising a SELP. In some aspects, the SELP embolizes an abnormal blood vessel in the AVM. Disclosed are methods of embolizing an AVM in a subject comprising administering to the subject a therapeutically effective amount of a composition comprising a SELP, wherein the SELP embolizes an abnormal blood vessel in the AVM. |
| FILED | Friday, September 04, 2020 |
| APPL NO | 17/640627 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 38/39 (20130101) Original (OR) Class A61K 49/0034 (20130101) A61K 49/0073 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230219073 | Mi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Faqrul A. Chowdhury (Ann Arbor, Michigan); The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zetian Mi (Ann Arbor, Michigan); Yongjie Wang (Berkeley, California); Faqrul A. Chowdhury (Montreal, Canada) |
| ABSTRACT | A photocatalytic device includes a substrate having a surface, and an array of conductive projections supported by the substrate and extending outward from the surface of the substrate. Each conductive projection of the array of conductive projections has a semiconductor composition. The semiconductor composition establishes a photochemical diode. The surface may be nonplanar such that subsets of the array of conductive projections are oriented at different angles. |
| FILED | Friday, March 26, 2021 |
| APPL NO | 17/914597 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/088 (20130101) B01J 19/122 (20130101) B01J 23/75 (20130101) B01J 23/464 (20130101) B01J 27/24 (20130101) B01J 35/004 (20130101) Original (OR) Class B01J 35/0013 (20130101) B01J 35/0033 (20130101) B01J 37/06 (20130101) B01J 37/0228 (20130101) B01J 37/0244 (20130101) B01J 2219/0843 (20130101) B01J 2219/1203 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230219283 | LEIBIG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CHROMATIC 3D MATERIALS, INC. (North Golden Valley, Minnesota) |
| ASSIGNEE(S) | CHROMATIC 3D MATERIALS, INC. (North Golden Valley, Minnesota) |
| INVENTOR(S) | Cora LEIBIG (Maple Grove, Minnesota); Theresa LEIBIG (Maple Grove, Minnesota); Michael GARROD (Minnetrista, Minnesota); Garth BENSON (Burnsville, Minnesota) |
| ABSTRACT | A three-dimensional object production process and system comprising providing a thermoset printing apparatus comprising a mixing chamber to receive and mix at least a first reactive component and a second reactive component to provide a thermosetting material, an extrusion nozzle, at least one actuator coupled to the extrusion nozzle, and a controller, wherein the controller generates a printing path for the 3D printing process, executes a translation start command, a flow start command, a translation command, a flow command, a translation stop command, a flow stop command, and a reverse translation command to the thermoset printing apparatus during the 3D printing process, identifies an at least one discontinuity in the printing path, executes the flow stop command before the extrusion nozzle reaches the at least one discontinuity, executes the translation stop command before the at least one discontinuity, and executes a reverse translation command |
| FILED | Tuesday, June 08, 2021 |
| APPL NO | 18/000952 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/106 (20170801) Original (OR) Class B29C 64/209 (20170801) B29C 64/227 (20170801) B29C 64/393 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230219284 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Chao Wang (Chandler, Arizona); Shinhyuk Choi (Tempe, Arizona); Yu Yao (Chandler, Arizona); Jiawei Zuo (Tempe, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chao Wang (Chandler, Arizona); Shinhyuk Choi (Tempe, Arizona); Yu Yao (Chandler, Arizona); Jiawei Zuo (Tempe, Arizona) |
| ABSTRACT | A structural color image includes a metallic layer, a nanocomposite film, and a dielectric layer between and in direct contact with the metallic layer and the nanocomposite film. The metallic layer reflects visible light. The nanocomposite film reflects visible light and includes metallic nanoparticles in a polymeric material. |
| FILED | Friday, January 13, 2023 |
| APPL NO | 18/154257 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 35/0805 (20130101) B29C 64/106 (20170801) Original (OR) Class B29C 2035/0827 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/10 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230219846 | Fini et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Elham Fini (Phoenix, Arizona); Saba Shariati (Shenzhen, China PRC) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Elham Fini (Phoenix, Arizona); Saba Shariati (Shenzhen, China PRC) |
| ABSTRACT | A modified bitumen composition includes bitumen and a multiplicity of silica particles. Each silica particle is coupled to an acid component. Treating a modified bitumen includes contacting the modified bitumen with a flow of air and removing the flow of air after a length of time when a penetration grade of the bitumen decreases to a specified value. |
| FILED | Wednesday, January 11, 2023 |
| APPL NO | 18/153143 |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 14/06 (20130101) C04B 20/107 (20130101) Original (OR) Class C04B 26/26 (20130101) C04B 38/10 (20130101) C04B 2111/0075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220018 | Gillaspy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY (Blacksburg, Virginia); VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (Blacksburg, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Glenda Gillaspy (Blacksburg, Virginia); Catherine Freed (Blacksburg, Virginia); Sarah Phoebe Williams (Blacksburg, Virginia); Zhiwu Wang (Blacksburg, Virginia) |
| ABSTRACT | Described herein are engineered cells and plants that contain a heterologous Diadenosine and Diphosphoinositol Polyphosphate Phosphohydrolase (DDP1) polypeptide, a heterologous DDP1 encoding polynucleotide, a vector or vector system comprising a heterologous DDP1 encoding polynucleotide, or a combination thereof. Also described herein are methods of making and using the engineered cells and plants described herein. |
| FILED | Saturday, May 22, 2021 |
| APPL NO | 17/927082 |
| CURRENT CPC | Peptides C07K 14/39 (20130101) C07K 14/415 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8261 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220158 | Dishari |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shudipto Konika Dishari (Dhaka, Bangladesh) |
| ABSTRACT | Provided here are ion conducting materials including one or more macrocycles, and either one or more pendant groups or one or more backbone repeat units. The ion conducting materials exhibit distinctly high ion conductivity in thin film and bulk membrane applications, and further exhibit one or more of ion permselectivity, mechanical strength, self-assembly, stacking, and gating behavior. Further provided are methods for preparation and methods for use of the ion conducting materials. |
| FILED | Tuesday, April 20, 2021 |
| APPL NO | 17/996666 |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/3346 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/1027 (20130101) H01M 8/1032 (20130101) H01M 10/0565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220330 | Forgacs et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gabor Forgacs (Potsdam, New York); Francoise Suzanne Marga (Columbia, Missouri); Cyrille Norotte (Paris, France) |
| ABSTRACT | Structures and methods for tissue engineering include a multicellular body including a plurality of living cells. A plurality of multicellular bodies can be arranged in a pattern and allowed to fuse to form an engineered tissue. The arrangement can include filler bodies including a biocompatible material that resists migration and ingrowth of cells from the multicellular bodies and that is resistant to adherence of cells to it. Three-dimensional constructs can be assembled by printing or otherwise stacking the multicellular bodies and filler bodies such that there is direct contact between adjoining multicellular bodies, suitably along a contact area that has a substantial length. The direct contact between the multicellular bodies promotes efficient and reliable fusion. The increased contact area between adjoining multicellular bodies also promotes efficient and reliable fusion. Methods of producing multicellular bodies having characteristics that facilitate assembly of the three-dimensional constructs are also provided. |
| FILED | Monday, October 31, 2022 |
| APPL NO | 18/051215 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/222 (20130101) A61L 27/225 (20130101) A61L 27/3625 (20130101) A61L 27/3691 (20130101) A61L 27/3886 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/10 (20130101) C12M 25/06 (20130101) C12M 25/14 (20130101) C12M 33/00 (20130101) C12M 35/08 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) C12N 5/0068 (20130101) Original (OR) Class C12N 5/0602 (20130101) C12N 5/0691 (20130101) C12N 2506/1307 (20130101) C12N 2506/1338 (20130101) C12N 2533/54 (20130101) C12N 2533/56 (20130101) C12N 2533/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220514 | PARK et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ah-Hyung Alissa PARK (New York, New York); Peng PENG (Emeryville, California); Haonan Danny HUANG (Glendora, California) |
| ABSTRACT | A plurality of different metals, including precious metals, platinum group metals, rare earth elements, alkaline earth metals, etc., can be electrochemically recovered from waste materials such as ashes and e-waste, e.g., printed circuit boards. Waste feed stocks are treated with supercritical CO2 (scCO2) and acid to produce a solid delaminated waste and a liquid delaminated waste for recovery of elemental metals and metal compounds from each. Carbonation reactions can be used to convert and recover alkaline earth metals from the liquid delaminated waste. The solid delaminated waste can yield a solid gold product, and be further treated along with the liquid delaminated waste via a solvent including one or more organic ligands that bind target metals to form metal-ligand complexes. Electrochemical separation of the different metals, e.g., via stepwise variation of pH to release the metals from organic ligands having different pKa values, yields high purity metal product streams. |
| FILED | Monday, January 09, 2023 |
| APPL NO | 18/094588 |
| CURRENT CPC | Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 1/00 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 3/16 (20130101) C22B 3/045 (20130101) Original (OR) Class C22B 4/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230221239 | PRALJAK et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Niksa PRALJAK (Cleveland, Ohio); Shamreen IRAM (Cleveland, Ohio); Utku GOREKE (Cleveland, Ohio); Michael HINCZEWSKI (Cleveland, Ohio); Ailis HILL (Cleveland, Ohio); Umut GURKAN (Cleveland, Ohio); Gundeep SINGH (Cleveland, Ohio) |
| ABSTRACT | In a disclosed example, a computer-implemented method includes storing image data that includes an input image of a blood sample within a blood monitoring device. The method also includes generating, by a machine learning model, a segmentation mask that assigns pixels in the input image to one of a plurality of classes, which correlate to respective known biophysical properties of blood cells. The method also includes extracting cell images from the input image based on the segmentation mask, in which each extracted cell image includes a respective cluster of the pixels assigned to a respective one of the plurality of classes. |
| FILED | Thursday, June 03, 2021 |
| APPL NO | 17/928976 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1475 (20130101) Original (OR) Class G01N 33/49 (20130101) G01N 2015/0073 (20130101) Image Data Processing or Generation, in General G06T 7/12 (20170101) Image or Video Recognition or Understanding G06V 10/25 (20220101) G06V 10/762 (20220101) G06V 10/764 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230221242 | Caldwell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee); Third Floor Materials, Inc. (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joshua D. Caldwell (Nashville, Tennessee); Edward Sachet (Nashville, Tennessee); Christopher Shelton (Nashville, Tennessee); Thomas G. Folland (Nashville, Tennessee) |
| ABSTRACT | Devices and methods for non-dispersive infrared (NDIR) sensing are disclosed. In one aspect, a non-dispersive infrared sensor is disclosed which, in one embodiment includes a nanophotonic infrared emitting metamaterial (NIREM) emitter configured to selectively emit radiation corresponding to a respective vibrational resonance frequency for each of a plurality of different analytes of interest. The broadband detector can be configured to detect photons associated with vibrational resonance of each of the plurality of analytes of interest in response to the emitted radiation from the NIREM emitter, in order to determine properties of one or more of the analytes of interest. |
| FILED | Thursday, January 12, 2023 |
| APPL NO | 18/096319 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/1702 (20130101) Original (OR) Class G01N 33/0027 (20130101) G01N 2021/1704 (20130101) G01N 2201/061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230221616 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ariz. Bd. of Reg. on Behalf of the Univ. of Ariz. (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zheshen Zhang (Tucson, Arizona); Shuai Liu (Tucson, Arizona); Bo-Han Wu (Tucson, Arizona) |
| ABSTRACT | A photonic integrated circuit (PIC) includes a first microresonator that generates a two-mode squeezed vacuum using spontaneous four-wave mixing. Specifically, the first microresonator uses a nonlinear optical medium to convert two pump photons into a pair of entangled signal and idler photons. Due to imperfect conversion efficiency, some of the pump light may co-propagate with the signal light and idler light. To remove this “unconverted” pump light, the PIC includes a second microresonator that is tuned to resonate with only the pump light. The second microresonator is located after the first microresonator and couples the unconverted pump light into a waveguide that guide the light off the PIC. Thus, the second microresonator acts as a notch filter. Integrating this pump filter onto the PIC adds negligibly to the path length of the squeezed light, and therefore saves the propagation losses incurred when using a much larger off-chip filter. |
| FILED | Tuesday, June 15, 2021 |
| APPL NO | 18/000901 |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/365 (20130101) G02F 1/3503 (20210101) G02F 1/3536 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230223113 | Ragan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Regina Ragan (Irvine, California); Allon Hochbaum (Irvine, California); William John Thrift (San Francisco, California) |
| ABSTRACT | Rapid antimicrobial susceptibility testing (AST) can be an integral tool to mitigate the unnecessary use of powerful and broad spectrum antibiotics that leads to the proliferation of multi-drug resistant bacteria. Methods and systems for a sensor platform composed of surface enhanced Raman scattering (SERS) sensors with surfaces having molecular control of nano architecture and surface chemistry and machine learning processes for analyzing SERS data, are described to detect metabolic profiles from susceptible antibiotic resistant bacteria strains for rapid AST. |
| FILED | Thursday, May 27, 2021 |
| APPL NO | 17/999674 |
| CURRENT CPC | Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/70 (20190201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230223207 | Kassegne et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | San Diego State University Research Foundation (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Samuel K. Kassegne (San Diego, California); Elisa Castagnola (San Diego, California); Surabhi Nimbalkar (San Diego, California) |
| ABSTRACT | A meta-material is disclosed that includes a first layer composed of graphene, and one or more additional layers, each composed of glassy carbon or graphene. A method of producing an engineered material includes depositing a graphene precursor on a substrate, pyrolyzing the graphene precursor to allow the formation of graphene, depositing a glassy carbon precursor the graphene, pyrolyzing to allow the formation of glassy carbon from the glassy carbon precursor, depositing a graphene precursor on the glassy carbon, and pyrolyzing the graphene precursor to allow the formation of graphene. |
| FILED | Tuesday, October 25, 2022 |
| APPL NO | 17/973439 |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/26 (20130101) Original (OR) Class H01G 11/32 (20130101) H01G 11/52 (20130101) H01G 11/86 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/62 (20130101) H01M 4/133 (20130101) H01M 4/366 (20130101) H01M 4/583 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230223485 | KELLEY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | MATHEW KELLEY (COLUMBIA, South Carolina); ANDREW B. GREYTAK (COLUMBIA, South Carolina); MVS CHANDRASHEKHAR (LEXINGTON, South Carolina); JOSHUA LETTON (COLUMBIA, South Carolina) |
| ABSTRACT | The present disclosure is directed to methods for producing a photovoltaic junction that can include coating a bare junction with a composition. In one embodiment, the composition includes a plurality of quantum dots to create a film; exposing the film to a ligand to create a first layer; coating the first layer with the composition to form a film on the first layer; and exposing the film on the first layer to the ligand to create a second layer. |
| FILED | Monday, December 05, 2022 |
| APPL NO | 18/074665 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/07 (20130101) H01L 31/18 (20130101) H01L 31/108 (20130101) H01L 31/0312 (20130101) H01L 31/0324 (20130101) H01L 31/0336 (20130101) H01L 31/1848 (20130101) H01L 31/03048 (20130101) H01L 31/022408 (20130101) H01L 31/035218 (20130101) Original (OR) Class Organic electric solid-state devices H10K 30/00 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20230223651 — OXIDIZED BACTERIAL CELLULOSE SEPARATOR FOR BATTERIES AND METHOD FOR PRODUCING THE SAME
| US 20230223651 | Fan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Zhaoyang Fan (Chandler, Arizona); Wenyue Li (Chandler, Arizona); Shu Wang (Chandler, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Zhaoyang Fan (Chandler, Arizona); Wenyue Li (Chandler, Arizona); Shu Wang (Chandler, Arizona) |
| ABSTRACT | A separator for a lithium-based battery, and method for fabricating the same is disclosed. The method includes oxidizing cellulose fibrils to form oxidized cellulose having carboxylic functional groups, decorating the oxidized cellulose with nanoparticles, and forming the nanoparticle-decorated oxidized cellulose into a film to become the separator for the lithium-based battery. The cellulose may be a bacterial cellulose. The cellulose fibrils may be oxidized through a TEMPO oxidation. Decorating the oxidized cellulose with nanoparticles may include introducing a precursor solution to the oxidized cellulose that reacts with hydroxyl groups of the oxidized cellulose while preserving the carboxylic functional groups, causing the nanoparticles to nucleate on the surface of the oxidized cellulose. The nanoparticles may be composed of an oxide material. The oxide material may be SiO2. The precursor solution may be tetraethyl orthosilicate (TEOS). |
| FILED | Thursday, January 12, 2023 |
| APPL NO | 18/154037 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/052 (20130101) H01M 50/403 (20210101) H01M 50/431 (20210101) H01M 50/434 (20210101) H01M 50/446 (20210101) H01M 50/4295 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230223869 | Reitz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | C-Motive Technologies, Inc. (Middleton, Wisconsin) |
| ASSIGNEE(S) | C-Motive Technologies, Inc. (Middleton, Wisconsin) |
| INVENTOR(S) | Graham T. Reitz (Middleton, Wisconsin); William D. Butrymowicz (Middleton, Wisconsin); Justin K. Reed (Madison, Wisconsin); Daniel C. Ludois (Middleton, Wisconsin) |
| ABSTRACT | An electrostatic machine includes a drive electrode and a stator electrode. The drive electrode and the stator electrode are separated by a gap and form a capacitor. The drive electrode is configured to move with respect to the stator electrode. The electrostatic machine further includes a housing configured to enclose the drive electrode and the stator electrode. The stator electrode is fixed to the housing. The electrostatic machine also includes a dielectric fluid that fills a void defined by the housing, the drive electrode, and the stator electrode. The dielectric fluid includes an ester. |
| FILED | Friday, March 03, 2023 |
| APPL NO | 18/117239 |
| CURRENT CPC | Electric Machines Not Otherwise Provided for H02N 1/004 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230224599 | Gutierrez Barragan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Felipe Gutierrez Barragan (Alameda, California); Yuhao Liu (Madison, Wisconsin); Atul Ingle (Madison, Wisconsin); Mohit Gupta (Madison, Wisconsin); Andreas Velten (Madison, Wisconsin) |
| ABSTRACT | In accordance with some embodiments, systems, methods, and media for high dynamic range imaging using single-photon and conventional image sensor data are provided. In some embodiments, the system comprises: first detectors configured to detect a level of photons proportional to incident photon flux; second detectors configured to detect arrival of individual photons; a processor programmed to: receive, from the first detectors, first values indicative of photon flux from a scene with a first resolution; receive, from the second detectors, second values indicative of photon flux from the scene with a lower resolution; provide a first encoder of a trained machine learning model first flux values based on the first values, provide the second encoder of the model second flux values; receive, as output, values indicative of photon flux from the scene; and generate a high dynamic range image based on the third plurality of values. |
| FILED | Monday, January 10, 2022 |
| APPL NO | 17/572236 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14634 (20130101) H01L 27/14645 (20130101) Pictorial Communication, e.g Television H04N 5/35563 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20230218019 | Fuller |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States Govemment as represensted by The Department ofVeterans Affairs (Washington, District of Columbia); REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Scott C. Fuller (Sacramento, California) |
| ABSTRACT | A mask can comprise a covering material that is sufficiently sized to extend over a mouth and a nose on a head of a wearer. The covering material can have an outer surface and an inner surface. The covering material can define an opening therethrough. At least one transparent membrane can be coupled to the covering material and cover the opening in the covering material. The at least one transparent membrane can define a hole therethrough. An elongate conduit can define an interior passage having a central axis. The elongate conduit can be coupled to the at least one transparent membrane so that the central axis of the interior passage is aligned with the hole. The mask can further comprise at least one securing element for securing the mask to the head of the wearer. |
| FILED | Friday, May 21, 2021 |
| APPL NO | 17/927193 |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 13/11 (20130101) Original (OR) Class Diagnosis; Surgery; Identification A61B 90/05 (20160201) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 2210/0618 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230218639 | Ren et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Durect Corporation (Cupertino, California); Virginia Commonwealth University (, None); THE UNITED STATE GOVERNMENT as represented by THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | Virginia Commonwealth University (Richmond, Virginia) |
| INVENTOR(S) | Shunlin Ren (Richmond, Virginia); Yaping Wang (Richmond, Virginia); WeiQi Lin (Emerald Hills, California); James E. Brown (Los Gatos, California); Felix Theeuwes (Los Altos Hills, California) |
| ABSTRACT | Aspects of the present disclosure include methods for treating at least one of depression, neurodegenerative disease, multiple sclerosis, Parkinson's disease, spinocerebellar degeneration, Friedreich ataxia, ataxia-telangiectasia, progressive supranuclear palsy, Huntington's disease, striatonigral degeneration, olivopontocerebellar atrophy, Shy-Drager syndrome, schizophrenia, schizoaffective disorder, manic-depression (bipolar) disorder, disturbed or abnormal circadian entrainment, childhood Alice in Wonderland syndrome, childhood acute cerebellar ataxia, and Alzheimer's disease. In some instances, methods include treating an addiction to a drug, such as alcohol addiction, cocaine addiction or amphetamine addiction. In practicing the subject methods, an effective amount of at least one compound selected from 25-hydroxycholesterol-3-sulfate (25HC3S), 25-hydroxycholesterol-disulfate (25HCDS), 27-hydroxycholesterol-3-sulfate (27HC3S), 27-hydroxycholesterol-disulfate (27HCDS), 24-hydroxycholesterol-3-sulfate (24HC3S), 24-hydroxycholesterol-disulfate (24HCDS), and 24,25-epoxycholesterol-3-sulfate, or salt thereof is administered to the subject. |
| FILED | Friday, June 25, 2021 |
| APPL NO | 18/008560 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/575 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230219893 | Mallipattu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia); Icahn School of Medicine at Mount Sinai (New York, New York); The Research Foundation for the State University of New York (Albany, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sandeep Mallipattu (St. James, New York); Bhaskar Das (West Nyack, New York) |
| ABSTRACT | The present disclosure is concerned with small molecule modulators of KLF15 signaling useful for treating various disorders such as, for example, kidney disease (e.g., chronic kidney disease), heart disease, obesity, or a neurodegenerative disorder (e.g., amyotrophic lateral sclerosis (ALS), Alzheimer's disease, Parkinson's disease, spinal muscular atrophy, traumatic brain injury, vascular dementia, Huntington's disease, mental retardation, and attention deficit and hyperactivity disorder (ADHD)). This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Thursday, March 02, 2023 |
| APPL NO | 18/116593 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/573 (20130101) Acyclic or Carbocyclic Compounds C07C 321/20 (20130101) Heterocyclic Compounds C07D 213/74 (20130101) C07D 213/85 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230219958 | Suto et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Southern Research Institute (Birmingham, Alabama); UAB Research Foundation (Birmingham, Alabama); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark J. Suto (Homewood, Alabama); Bini Mathew (Hoover, Alabama); Corinne E. Augelli-Szafran (Homewood, Alabama); Marina Fosso Yatchang (Chelsea, Alabama); Mohammad Athar (Hoover, Alabama); Anupam Agarwal (Mountain Brook, Alabama); Ritesh Kumar Srivastava (Vestavial Hills, Alabama); Suhail Muzaffar (Birmingham, Alabama); Jasim Khan (Birmingham, Alabama) |
| ABSTRACT | The present disclosure is concerned with purine diamine compounds for the treatment of conditions associated with BRD4, RIP3K, and/or IL6 signaling dysfunction such as, for example, cancer (e.g., lung cancer, skin cancer, bladder cancer, kidney cancer, liver cancer), arsenicosis, arsenic poisoning, inflammation, skin lesions, dysfunction of systemic organs, and skin blisters. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Tuesday, January 10, 2023 |
| APPL NO | 18/095429 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 39/02 (20180101) Heterocyclic Compounds C07D 473/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230223125 | Gaweda et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky); United States Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Adam E. Gaweda (Jeffersonville, Indiana); Michael E. Brier (Rossville, Tennessee); Eleanor D. Lederer (Louisville, Kentucky) |
| ABSTRACT | The present invention relates to systems and methods for personalized dosing of pharmacologic agents. In particular, the presently-disclosed subject matter relates to a computer-based system and method for personalized dosing of one or more pharmacologic agents to optimize one or more therapeutic responses. In some embodiments, the computer-based system and method provides for a computer-based model of a complex biological system useful for training machine learning agents for optimizing personalized dosing of pharmacological agents. |
| FILED | Tuesday, May 04, 2021 |
| APPL NO | 17/997667 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/10 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 20230218226 | Reed et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | David A. Reed (Baltimore, Maryland); George C. Emmett (Wilmington, Delaware) |
| ABSTRACT | In an example, a method of detecting cyanide exposure of an individual includes: measuring a thiocyanate level of the individual which includes placing saliva of the individual in contact with a chemical indicator to measure the thiocyanate level and measuring thiocyanate (SCN−) catalyzed by enzyme rhodanese of the individual; comparing the measured thiocyanate level to a preset thiocyanate threshold to determine whether the measured thiocyanate level is above the preset thiocyanate threshold indicating a level of cyanide poisoning for which a medical procedure is recommended to manage health effects of the exposure; and performing the medical procedure if the measured thiocyanate level is above the preset thiocyanate threshold and not performing the medical procedure if the measured thiocyanate level is not above the preset thiocyanate threshold. |
| FILED | Tuesday, January 17, 2023 |
| APPL NO | 18/097978 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/4845 (20130101) Original (OR) Class A61B 5/14551 (20130101) A61B 10/0051 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230224569 | Vemury |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Arun Vemury (North Bethesda, Maryland) |
| ABSTRACT | A system for generating a privacy protected image. The system may have a detection logic and obscuring logic configured to detect one or more identity-correlated object categories. The system may provide automatic selection of a type of obscuring to be used based on the detected category; wherein said automatic selection includes automatically selecting among a plurality of different, category specific types of reversible obscuring. The detection logic and obscuring logic may include an automatic category-specific selecting between irreversible obscuring and reversible obscuring. The system may comprise a privacy protected image output logic configured to generate the privacy protected image. |
| FILED | Thursday, March 16, 2023 |
| APPL NO | 18/122415 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/6245 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 5/002 (20130101) G06T 7/20 (20130101) G06T 7/70 (20170101) G06T 2207/30201 (20130101) Image or Video Recognition or Understanding G06V 10/25 (20220101) G06V 10/764 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230224712 | Lim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Jason Lim (Alexandria, Virginia); Daniel Boyd (Arlington, Virginia); Chang Ellison (Arlington, Virginia); William Washington (North Potomac, Maryland) |
| ABSTRACT | In an example, a provider system receives from a client device a request for client sign-on access. The provider system sends to the client device a request for identification information of the client. The provider system receives client information associated with a first mobile identification credential (MIC) which the client device received from an authorizing party system (APS), the client having consented to release the client information to the provider system, and the client information having been verified by the APS. The provider system uses the verified client information associated with the first MIC to verify or not verify the identity of the client. The provider system verifies the identity of the client before granting the client the request for client sign-on access. |
| FILED | Thursday, March 02, 2023 |
| APPL NO | 18/116503 |
| CURRENT CPC | Wireless Communication Networks H04W 12/06 (20130101) H04W 12/08 (20130101) H04W 12/71 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20230217935 | Yoon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Antithesis Foods Inc. (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Antithesis Foods Inc. (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Ashton Yoon (Philadelphia, Pennsylvania); Jason Goodman (Philadelphia, Pennsylvania); Allie Hall (Philadelphia, Pennsylvania) |
| ABSTRACT | A system and method for the production of doughs and products using textured pulse proteins, including legume-based crunchy snack foods, said method comprising the following steps: homogenization of ingredients in the form of dry feed powders, mixing and hydration of powders with liquid ingredients to form a dough, forming of the dough into form factors, drying and expansion of the form factors to develop texture and shelf stability, and cooling. |
| FILED | Thursday, December 22, 2022 |
| APPL NO | 18/145831 |
| CURRENT CPC | Treatment, e.g Preservation, of Flour or Dough, e.g by Addition of Materials; Baking; Bakery Products; Preservation Thereof A21D 2/266 (20130101) Original (OR) Class A21D 2/362 (20130101) A21D 8/02 (20130101) A21D 10/002 (20130101) A21D 13/06 (20130101) A21D 13/045 (20170101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230220113 | GARCIA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | AQUALUNG THERAPEUTICS CORP. (TUCSON, Arizona) |
| ASSIGNEE(S) | AQUALUNG THERAPEUTICS CORP. (TUCSON, Arizona) |
| INVENTOR(S) | JOE G.N. GARCIA (TUCSON, Arizona); DARRAGH MACCANN (CO. DERRY, Ireland) |
| ABSTRACT | Anti-nicotinamide phosphoribosyltransferase (NAMPT) antibodies, or antigen binding fragments thereof, are described, as well as methods for treating a subject having a (NAMPT)-associated local and/or systemic inflammatory disorder. |
| FILED | Friday, September 09, 2022 |
| APPL NO | 17/941741 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) A61P 31/14 (20180101) Peptides C07K 16/40 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/34 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230221242 | Caldwell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee); Third Floor Materials, Inc. (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joshua D. Caldwell (Nashville, Tennessee); Edward Sachet (Nashville, Tennessee); Christopher Shelton (Nashville, Tennessee); Thomas G. Folland (Nashville, Tennessee) |
| ABSTRACT | Devices and methods for non-dispersive infrared (NDIR) sensing are disclosed. In one aspect, a non-dispersive infrared sensor is disclosed which, in one embodiment includes a nanophotonic infrared emitting metamaterial (NIREM) emitter configured to selectively emit radiation corresponding to a respective vibrational resonance frequency for each of a plurality of different analytes of interest. The broadband detector can be configured to detect photons associated with vibrational resonance of each of the plurality of analytes of interest in response to the emitted radiation from the NIREM emitter, in order to determine properties of one or more of the analytes of interest. |
| FILED | Thursday, January 12, 2023 |
| APPL NO | 18/096319 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/1702 (20130101) Original (OR) Class G01N 33/0027 (20130101) G01N 2021/1704 (20130101) G01N 2201/061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 20230221233 | PARLAK |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | QATCH TECHNOLOGIES (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zehra PARLAK (Chapel Hill, North Carolina) |
| ABSTRACT | A method is provided to measure viscosity of an analyte using a microfluidic piezoelectric sensor including a channel on an active area of a piezoelectric resonator substrate. The microfluidic piezoelectric sensor is driven so that the active area of the piezoelectric resonator substrate generates shear motion in a direction of shear motion displacement that is parallel with respect to a first surface of the piezoelectric resonator substrate. A high shear-rate viscosity of the analyte is determined based on a shift in resonance of the microfluidic piezoelectric sensor while driving the microfluidic piezoelectric sensor with the analyte in the channel. A low shear-rate viscosity of the analyte is determined by detecting flow of the analyte through the channel based on tracking shifts in resonance of the microfluidic piezoelectric sensor. Related sensors are also discussed. |
| FILED | Friday, October 16, 2020 |
| APPL NO | 17/768937 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 11/16 (20130101) Original (OR) Class G01N 2011/0073 (20130101) Electric solid-state devices not otherwise provided for H10N 30/208 (20230201) H10N 30/302 (20230201) H10N 30/853 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 20230221229 | ZANOTTO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey) |
| INVENTOR(S) | Damiano ZANOTTO (Jersey City, New Jersey); Ton DUONG (Glen Ridge, New Jersey) |
| ABSTRACT | A sensor apparatus for footwear includes at least one pair of light sources and at least one pair of light receivers, each light receiver being positioned and configured to receive light emitted from a respective one of the light sources. A pair of movable curtains functions to adjust the amount of light received by the pair of light receivers. The curtains are movable conjointly such that the amount of light received by one of the light receivers is inversely proportional to the amount of light received by the other light receiver. (FIG. 1B). |
| FILED | Friday, May 28, 2021 |
| APPL NO | 17/928229 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/112 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/24 (20130101) Original (OR) Class G01N 2203/0025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 20230223254 | Hazbun et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GlobalFoundries U.S. Inc. (Malta, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ramsey Hazbun (Colchester, Vermont); Mark Levy (Williston, Vermont); Alvin Joseph (Williston, Vermont); Siva P. Adusumilli (South Burlington, Vermont) |
| ABSTRACT | Structures including a compound-semiconductor-based device and a silicon-based device integrated on a semiconductor substrate and methods of forming such structures. The structure includes a first semiconductor layer having a top surface and a faceted surface that fully surrounds the top surface. The top surface has a first surface normal, and the faceted surface has a second surface normal that is inclined relative to the first surface normal. A layer stack that includes second semiconductor layers is positioned on the faceted surface of the first semiconductor layer. Each of the second semiconductor layers contains a compound semiconductor material. A silicon-based device is located on the top surface of the first semiconductor layer, and a compound-semiconductor-based device is located on the layer stack. |
| FILED | Monday, January 10, 2022 |
| APPL NO | 17/571932 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0243 (20130101) Original (OR) Class H01L 21/02381 (20130101) H01L 21/02433 (20130101) H01L 21/76224 (20130101) H01L 27/085 (20130101) H01L 29/2003 (20130101) H01L 29/66462 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20230224143 — MODULATION-AGNOSTIC TRANSFORMATIONS USING UNITARY BRAID DIVISIONAL MULTIPLEXING (UBDM)
| US 20230224143 | ROBINSON |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rampart Communications, Inc. (Linthicum Heights, Maryland) |
| ASSIGNEE(S) | Rampart Communications, Inc. (Linthicum Heights, Maryland) |
| INVENTOR(S) | Matthew Brandon ROBINSON (Millersville, Maryland) |
| ABSTRACT | A method for implementing a fast UBDM transform includes receiving a first, input vector via a processor, and partitioning the first vector to produce a magnitude vector and a sign vector. A second vector, including a modified magnitude vector and a modified sign vector, is generated by: applying a permutation to the magnitude vector to produce the modified magnitude vector, converting the sign vector, based on an algorithm, into an intermediate sign vector, and applying nonlinear layers to the intermediate sign vector. Each nonlinear layer includes a permutation, an S-box transformation, a diffusive linear operation and/or an Xor operation. Multiple linear layers are applied to the second vector to produce a third vector, the third vector being a transformed version of the first vector. A first signal representing the third vector is sent to at least one transmitter for transmission of a second signal representing the transformed data vector. |
| FILED | Tuesday, March 21, 2023 |
| APPL NO | 18/187630 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0637 (20130101) Original (OR) Class H04L 27/2627 (20130101) H04L 2209/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, July 13, 2023.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
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HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-applications-20230713.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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