FedInvent™ Patent Applications
Application Details for Thursday, July 20, 2023
This page was updated on Thursday, July 20, 2023 at 12:14 PM GMT
Department of Health and Human Services (HHS)
| US 20230225315 | Steinmetz et al. |
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| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicole F. Steinmetz (San Diego, California); Paul L. Chariou (Cleveland, Ohio) |
| ABSTRACT | A method of delivering an agricultural composition to a plant including determining a dose of the agricultural composition required to deliver a treatment effective amount of the at least one agrochemical agent to a target soil depth using a computational model, the agricultural composition including a plurality of plant viral nanoparticles (VNPs) and/or virus-like particles (VLPs) and at least one agrochemical agent, and applying the determined dose of the agricultural composition to the plant. |
| FILED | Monday, January 27, 2020 |
| APPL NO | 17/425909 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/28 (20130101) Original (OR) Class A01N 63/40 (20200101) Biocidal, Pest Repellant, Pest Attractant or Plant Growth Regulatory Activity of Chemical Compounds or Preparations A01P 5/00 (20210801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230225623 | Carek et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois); Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew M. Carek (Evanston, Illinois); James A. Heller (Evanston, Illinois); Mozziyar Etemadi (Evanston, Illinois); Avidor B. Kazen (Evanston, Illinois); Omer T. Inan (Atlanta, Georgia); Venu G. Ganti (Atlanta, Georgia) |
| ABSTRACT | An exemplary embodiment of the present disclosure provides systems and methods for non-invasively measuring blood pressure, the system and methods comprise a wearable device having a first surface, a first sensor positioned on the first surface of the wearable device, the first sensor configured to receive a first signal, wherein the first signal is indicative of a first blood-volume change in a first vessel of a subject, a second sensor positioned within the wearable device, the second sensor configured to receive a second signal, wherein the second signal is indicative of a cardiac mechanical motion of the subject, and a processor positioned within the wearable device, the processor configured to generate an output based at least on the first signal and the second signal, the output representing a blood pressure measurement of the subject. |
| FILED | Friday, March 19, 2021 |
| APPL NO | 17/906672 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/318 (20210101) A61B 5/02108 (20130101) Original (OR) Class A61B 5/6802 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230225636 | Datta et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Sandeep Robert Datta (Cambridge, Massachusetts); Alexander B. Wiltschko (Cambridge, Massachusetts); Matthew J. Johnson (Cambridge, Massachusetts); Geetika Bajaj (Cupertino, California) |
| ABSTRACT | Systems and methods are disclosed to objectively identify sub-second behavioral modules in the three-dimensional (3D) video data that represents the motion of a subject. Defining behavioral modules based upon structure in the 3D video data itself—rather than using a priori definitions for what should constitute a measurable unit of action—identifies a previously-unexplored sub-second regularity that defines a timescale upon which behavior is organized, yields important information about the components and structure of behavior, offers insight into the nature of behavioral change in the subject, and enables objective discovery of subtle alterations in patterned action. The systems and methods of the invention can be applied to drug or gene therapy classification, drug or gene therapy screening, disease study including early detection of the onset of a disease, toxicology research, side-effect study, learning and memory process study, anxiety study, and analysis in consumer behavior. |
| FILED | Wednesday, March 08, 2023 |
| APPL NO | 18/180677 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/00 (20130101) A61B 5/1123 (20130101) A61B 5/1128 (20130101) Original (OR) Class A61B 5/7267 (20130101) A61B 2503/40 (20130101) A61B 2503/42 (20130101) A61B 2576/00 (20130101) Electric Digital Data Processing G06F 18/295 (20230101) G06F 18/2135 (20230101) Image or Video Recognition or Understanding G06V 10/85 (20220101) G06V 10/147 (20220101) G06V 10/7715 (20220101) G06V 40/20 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230225685 | Altunbas |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the university of Colorado, a body corporate (Denver, Colorado) |
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| INVENTOR(S) | Cem Altunbas (Denver, Colorado) |
| ABSTRACT | A portable computed tomography (CT) system includes an O-shaped gantry defining an opening, an x-ray source operably coupled to the O-shaped gantry, and a flat panel detector (FPD) coupled to the O-shaped gantry and having a two-dimensional anti-scatter grid (2D ASG) coupled to a side of the FPD facing the opening. With the O-shaped gantry having the FPD, the object may be imaged in a first field of view (FOV) with the detector arranged in a centered geometry. Then, the detector may be arranged in an offset geometry, through-holes of the ASG may be aligned with x-ray emission paths of the x-ray source, and the object may be imaged in a second FOV with the detector arranged in the offset geometry. |
| FILED | Friday, January 06, 2023 |
| APPL NO | 18/151363 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/4035 (20130101) A61B 6/4216 (20130101) A61B 6/4283 (20130101) A61B 6/4291 (20130101) Original (OR) Class Measurement of Nuclear or X-radiation G01T 1/2002 (20130101) G01T 1/2006 (20130101) G01T 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230225850 | Kilbride et al. |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
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| INVENTOR(S) | Bridget F. Kilbride (San Francisco, California); Bradford R.H. Thorne (San Francisco, California); Steven W. Hetts (Hillsborough, California); Vitaliy Lvovich Rayz (Thiensville, Wisconsin) |
| ABSTRACT | In vivo and ex vivo positionable filtration devices are provided that are functionalized to bind one or more therapeutic agents in blood flowing in a blood vessel. |
| FILED | Monday, December 19, 2022 |
| APPL NO | 18/084230 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/01 (20130101) Original (OR) Class Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/3615 (20140204) A61M 1/3687 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230225964 | Wang et al. |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
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| INVENTOR(S) | Joseph Wang (San Diego, California); Rodolfo Andres Mundaca Uribe (La Jolla, California); Berta Esteban-Fernandez de Avila (San Diego, California); Ronnie Fang (San Diego, California); Liangfang Zhang (San Diego, California) |
| ABSTRACT | Disclosed are methods, materials and devices that pertain to a microstirring pill technology with built-in mixing capability for oral drug delivery that greatly enhances bioavailability of its therapeutic payload. In some aspects, a drug delivery device includes a pill matrix dissolvable in a fluid medium and loaded with a plurality of drug payloads; and a plurality of micro stirrers embedded in the pill matrix and configured to create a local fluid transport upon interacting with a biological fluid surrounding the microstirring pill. |
| FILED | Wednesday, January 18, 2023 |
| APPL NO | 18/156328 |
| CURRENT CPC | Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 3/06 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0007 (20130101) A61K 9/0053 (20130101) Original (OR) Class A61K 9/1611 (20130101) A61K 9/2018 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226005 | Vinetz |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
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| INVENTOR(S) | Joseph M. Vinetz (New Haven, Connecticut) |
| ABSTRACT | The present disclosure relates, in part, to methods of treating, ameliorating, shortening duration, and/or reversing at least one symptom and/or complication in a human subject with a coronavirus infection with camostat, or a pharmaceutically acceptable salt or solvate thereof. The present disclosure further relates to a method of preventing and/or reducing the occurrence of long COVID, and/or a symptom and/or complication thereof, hospitalization, and/or death in a human subject with a SARS-CoV-2 infection with camostat, or a pharmaceutically acceptable salt or solvate thereof. In certain embodiments, the camostat salt is camostat mesylate. |
| FILED | Tuesday, June 29, 2021 |
| APPL NO | 18/002477 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/245 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226016 | Eisenberg et al. |
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| APPLICANT(S) | The Regents of University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David S. Eisenberg (Los Angeles, California); Paul M. Seidler (Los Angeles, California); Patrick G. Harran (Santa Monica, California); Darsheed Mustafa (Los Angeles, California); Melinda Balbirnie (Los Angeles, California); Anton EI Khoury (Sherman Oaks, California); Kevin A. Murray (Los Angeles, California) |
| ABSTRACT | Disclosed are agents that include a flavanol (e.g., epigallocatechin-3-gallate) or a flavanol analog, a linker coupled to the flavanol or the flavanol analog, and a carrier (e.g., iron oxide nanoparticle) coupled to the linker. The disclosed agents can be used in methods for destabilizing a tau amyloid fibril, and for treating a tauopathy (e.g., Alzheimer's disease, progressive supranuclear palsy) in a subject. |
| FILED | Friday, May 14, 2021 |
| APPL NO | 17/927639 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/353 (20130101) Original (OR) Class A61K 31/4192 (20130101) A61K 47/60 (20170801) A61K 47/6923 (20170801) A61K 47/6929 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226050 | DALY et al. |
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| APPLICANT(S) | ViiV Healthcare Company (Wilmington, Delaware); The United State of America, as represented by Th Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michele B. DALY (Collegeville, Pennsylvania); Jose Gerardo GARCIA LERMA (Collegeville, Pennsylvania); Walid M. HENEINE (Collegeville, Pennsylvania); William Robert SPREEN (Collegeville, Pennsylvania); Peter Evan Owen WILLIAMS (Beerse, Belgium) |
| ABSTRACT | A method of achieving HIV viral remission in a patient in need thereof, comprising the steps of: after exposure of the patient to the HIV virus, administering an early antiretroviral therapy (eART) of therapeutically effective amounts of cabotegravir and rilpivirine long-acting antiretrovirals, and after eART suppression of the virus, discontinuing said early antiretroviral therapy. |
| FILED | Wednesday, June 30, 2021 |
| APPL NO | 18/002494 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/505 (20130101) A61K 31/675 (20130101) A61K 31/4985 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226079 | Ray et al. |
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| APPLICANT(S) | Saint Louis University (St. Louis, Missouri) |
| ASSIGNEE(S) | Saint Louis University (St. Louis, Missouri) |
| INVENTOR(S) | Ratna Ray (St. Louis, Missouri); Subhayan Sur (St. Louis, Missouri) |
| ABSTRACT | This invention relates to a novel method of treating solid tumors of the head and neck. More specifically, the invention relates to the use of Momordicine-I (M-I), an extract of bitter melon (Momordica charantia), to treat solid tumors, particularly those of the head and neck as well as the breast. Methods and compositions are disclosed related to administrating Momordicine-I with lipophilic solvents to subjects in need. |
| FILED | Saturday, January 14, 2023 |
| APPL NO | 18/154810 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/575 (20130101) Original (OR) Class A61K 47/20 (20130101) A61K 47/40 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226088 | GOMER et al. |
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| APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | Richard H. GOMER (College Station, Texas); Darrell PILLING (Bryan, Texas); Tejas KARHADKAR (San Mateo, California) |
| ABSTRACT | The present disclosure relates to methods of treating Coronavirus-Associated Lung Damage (CALD) and cytokine storm using CALD-treating compounds. The methods can involve administering CALD-treating compounds to a patient suffering from CALD or cytokine storm. |
| FILED | Monday, June 07, 2021 |
| APPL NO | 18/009203 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4468 (20130101) A61K 31/7012 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) A61P 29/00 (20180101) A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226089 | KOFF et al. |
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| APPLICANT(S) | Atropos Therapeutics, Inc. (San Carlos, California) |
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| INVENTOR(S) | Andrew KOFF (Westbury, New York); Thomas B. NGUYEN (Missouri City, Texas) |
| ABSTRACT | The present disclosure relates to a method of treating or delaying onset of a disease associated with the accumulation of senescent cells in a subject comprising administering to the subject a therapeutically effective amount of a senosuppressor that modulates a number of ATRX foci per cell. |
| FILED | Monday, March 20, 2023 |
| APPL NO | 18/186412 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/65 (20130101) A61K 31/519 (20130101) A61K 31/704 (20130101) Original (OR) Class A61K 31/4709 (20130101) A61K 35/28 (20130101) A61K 36/53 (20130101) A61K 36/70 (20130101) A61K 36/79 (20130101) A61K 36/258 (20130101) A61K 36/488 (20130101) A61K 36/804 (20130101) A61K 36/815 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226095 | Chatila et al. |
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| APPLICANT(S) | The Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Talal Chatila (Belmont, Massachusetts); Hani Harb (Brookline, Massachusetts); Mehdi Benamar (Boston, Massachusetts) |
| ABSTRACT | Described herein are methods and compositions for treating a coronavirus infectious disease, e.g., COVID-19. Aspects of the invention relate to administering to a subject an agent that targets Notch4. |
| FILED | Friday, June 11, 2021 |
| APPL NO | 18/009605 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 31/7125 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226101 | Machielse et al. |
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| APPLICANT(S) | Mandos LLC (West Hollywood, California) |
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| INVENTOR(S) | Bernardus Nicolaas Machielse (North Potomac, Maryland); Allan Darling (North Potomac, Maryland) |
| ABSTRACT | This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C. |
| FILED | Wednesday, March 01, 2023 |
| APPL NO | 18/115898 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/724 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226102 | Machielse et al. |
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| APPLICANT(S) | Mandos LLC (West Hollywood, California) |
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| INVENTOR(S) | Bernardus Nicolaas Machielse (North Potomac, Maryland); Allan Darling (North Potomac, Maryland) |
| ABSTRACT | This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C. |
| FILED | Wednesday, March 01, 2023 |
| APPL NO | 18/115901 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/0019 (20130101) A61K 9/0085 (20130101) A61K 31/724 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226109 | Sunwoo et al. |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John Sunwoo (Stanford, California); Uriel Y. Moreno Nieves (Palo Alto, California); Joshua Tay (Redwood City, California); Saumyaa Saumyaa (Redwood City, California); June H. Shin (Redwood City, California); Nina Beryl Horowitz (Armonk, New York) |
| ABSTRACT | Natural killer cells are differentiated to an intraepithelial innate lymphoid cells (ielLC1)-like cell, with an increase in cytotoxic activity. Specifically, the disclosure provides a method for differentiating mammalian natural killer cells to adapt an ielLC1-like phenotype, the method comprising: differentiating peripheral natural killer (NK) cells in the presence of IL-15 and epithelial cells or plate coatings that mimic features of epithelial cells, to generate CD49a+ CD103+ cells having features and phenotype of ielLC1s, with enhanced cytotoxic activity and expression of Th1 type cytokines. |
| FILED | Friday, October 02, 2020 |
| APPL NO | 17/766019 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 2039/5156 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7055 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0646 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226116 | GOLDMAN et al. |
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| APPLICANT(S) | UNIVERSITY OF ROCHESTER (Rochester, New York) |
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| INVENTOR(S) | Steven A. GOLDMAN (Webster, New York); John MARIANI (Rochester, New York); Nguyen P.T. HUYNH (Cambridge, Massachusetts) |
| ABSTRACT | A method for rejuvenating glial progenitor cells and rejuvenated glial progenitor cells rejuvenated by such method are disclosed. The method comprises introducing a population of genetically modified glial progenitor cells into the brain and/or brain stem of a subject, wherein the genetically modified glial progenitor cells have increased expression of one or more genes compared to the same type of glial progenitor cells that have not been genetically modified, and wherein the one or more genes are selected from the group consisting of ARX, CEBPZ, DLX1, DLX2, ELK1, ETS1, ETV4, KLF16, MYBL2, MYC, NFYB, POU3F1, SMAD1, SOX3, SP5, TCF12, TFDP1, TP53, ZIC3 and ZNF195. |
| FILED | Sunday, October 16, 2022 |
| APPL NO | 18/046930 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/30 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0622 (20130101) C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) C12N 2506/02 (20130101) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226150 | BUTLER |
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| APPLICANT(S) | Hackensack Meridian Health Center for Discovery and Innovation (Nutley, New Jersey) |
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| INVENTOR(S) | Jason M. BUTLER (Nutley, New Jersey) |
| ABSTRACT | The described invention identifies endothelial cells within the perivascular niche as a crucial component in driving bone marrow (BM) inflammation and HSC dysfunction. We demonstrate that crosstalk between ERK-MAPK and NF-κB signaling pathways within the endothelium plays a key role in modulating the outcomes of chronic inflammation. Sustained activation of the MAPK pathway selectively within the endothelium of adult mice leads to inflammation-induced HSC dysfunction including loss of engraftment ability and a myeloid-biased output. HSC defects caused by endothelial MAPK activation are completely resolved upon simultaneous inhibition of endothelial NF-κB signaling. The described invention identifies Stem Cell Growth Factor alpha (SCGF) as a niche-derived factor that suppresses BM inflammation and enhances hematopoietic recovery following myelosuppressive injury. |
| FILED | Wednesday, November 25, 2020 |
| APPL NO | 17/780933 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) A61K 38/18 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226174 | MOE et al. |
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| APPLICANT(S) | Omvax, Inc. (San Francisco, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gregory MOE (Oakland, California); Serena GIUNTINI (Walnut Creek, California) |
| ABSTRACT | The disclosure provides native outer membrane vesicle (NOMV) vaccines containing a coronavirus receptor binding domain (RBD) modified to be a lipoprotein. Also provided are compositions comprising a meningococcal strain having a plasmid-borne gene encoding the SARS-CoV-2 RBD modified to be a lipoprotein. Also provided are a meningococcal strain and a NOMV vaccine containing a plasmid coding for the SARS-CoV-2 RBD with a promoter/enhancer and polyA sequence that provide for expression of the RBD in mammalian cells. |
| FILED | Friday, January 27, 2023 |
| APPL NO | 18/160835 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/215 (20130101) Original (OR) Class A61K 2039/521 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226188 | Monson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Bexion Pharmaceuticals Inc. (Covington, Kentucky) |
| ASSIGNEE(S) | Bexion Pharmaceuticals Inc. (Covington, Kentucky) |
| INVENTOR(S) | Ellen K. Monson (Cincinnati, Ohio); Xiaochen Wei (Covington, Kentucky); Ray Takigiku (Covington, Kentucky); Charles A. Cruze, III (West Chester, Ohio); Joseph W. Wyse (Nicholasville, Kentucky) |
| ABSTRACT | Disclosed are pharmaceutical compositions containing saposin C and phosphatidylserine that are useful for treating various cancers. |
| FILED | Friday, January 20, 2023 |
| APPL NO | 18/157689 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/19 (20130101) A61K 9/127 (20130101) A61K 38/18 (20130101) A61K 47/10 (20130101) A61K 47/12 (20130101) Original (OR) Class A61K 47/18 (20130101) A61K 47/24 (20130101) A61K 47/26 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/4705 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/40 (20130101) C12Q 2334/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226211 | STRUTT et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tara M. STRUTT (Orlando, Florida); Karl Kai MCKINSTRY (Orlando, Florida) |
| ABSTRACT | Disclosed are compositions comprising an IL-2:anti-IL-2 antibody (Ab) complex (IL-2C) and methods of using said N compositions for the treatment of microbial infections, autoimmune diseases, autoinflammatory diseases, or cancers as well the treatment of inflammatory conditions or reduction in inflammation caused by said microbial infections, autoimmune diseases, autoinflammatory diseases, or cancers. |
| FILED | Monday, April 26, 2021 |
| APPL NO | 17/920942 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6813 (20170801) A61K 47/6845 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/16 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226221 | Jaiswal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CHILDREN'S NATIONAL MEDICAL CENTER (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jyoti K. Jaiswal (Rockville, Maryland); Aurelia Defour (Marseille, France); Daniel Bittel (Washington, District of Columbia); Goutam Chandra (Silver Spring, Maryland); Sreetama Sen Chandra (Silver Spring, Maryland) |
| ABSTRACT | Compositions and methods for the treatment of muscular dystrophies are provided. |
| FILED | Tuesday, June 29, 2021 |
| APPL NO | 18/008422 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0058 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) C12N 15/86 (20130101) Enzymes C12Y 301/04012 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226225 | McIvor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota); REGENXBIO Inc. (Rockville, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | R. Scott McIvor (St. Louis Park, Minnesota); Lalitha R. Belur (St. Paul, Minnesota); Karen Kozarsky (Bala Cynwyd, Pennsylvania) |
| ABSTRACT | A method to prevent, inhibit or treat one or more symptoms associated with disease of the central nervous system by intranasally, intrathecally, intracerebrovascularly or intravenously administering a rAAV encoding a gene product associated with the disease, e.g., a mammal in which the gene product is absent or present at a reduced level relative to a mammal without the disease, in an amount effective, e.g., to provide for cross-correction. |
| FILED | Thursday, January 05, 2023 |
| APPL NO | 18/150740 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0043 (20130101) A61K 31/675 (20130101) A61K 38/47 (20130101) A61K 45/06 (20130101) A61K 48/0075 (20130101) Original (OR) Class A61K 48/0083 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 2750/14143 (20130101) C12N 2750/14171 (20130101) Enzymes C12Y 302/01076 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226228 | Tonge et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for the State University of New York (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for the State University of New York (Albany, New York) |
| INVENTOR(S) | Peter J. Tonge (Stony Brook, New York); Yong Li (Stony Brook, New York); Fareidoon Daryaee (Stony Brook, New York); Peter Michael Smith-Jones (Stony Brook, New York); Labros Meimetis (Stony Brook, New York) |
| ABSTRACT | This invention provides a composition comprising the compound having the structure: ethyl 2-[19F]F-4-nitrobenzoate, and at least one acceptable carrier. This invention also provides a method of detecting the presence of or location of bacteria cells in a subject which comprises determining if an amount of the compound or determining where an amount of the compound having the structure: is present in the subject at a period of time after administration of the compound or salt thereof to the subject, thereby detecting the presence of or location of the bacteria cells based on the amount of the compound determined to be present in the subject or detecting the location of the bacteria cells based on the location of the compound determined to be present in the subject. |
| FILED | Tuesday, May 04, 2021 |
| APPL NO | 17/997908 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/0402 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Acyclic or Carbocyclic Compounds C07C 201/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226258 | ABACI |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Hasan Erbil ABACI (New York, New York) |
| ABSTRACT | Engineered skin substitutes comprising an outer-facing portion and an inner-facing portion and methods of making the same are provided. The skin substitutes are configured to conform to a shape and a dimension of a body part of a subject, and have at least one surface that circles back on itself so as to enclose at least a portion of the body part. In some instances, dermis and epidermal layers can be formed in an air liquid interface. The exemplary skin substitutes are wearable and can be made to conform to a generic body part or a specific body part from a three-dimensional representation of the body part. |
| FILED | Tuesday, February 28, 2023 |
| APPL NO | 18/115402 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/3813 (20130101) Original (OR) Class A61L 27/3891 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0625 (20130101) C12N 2501/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226259 | KHAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mahmood KHAN (Dublin, Ohio); Heather POWELL (Mason, Ohio) |
| ABSTRACT | The present disclosure relates to a biocompatible patch and methods of use thereof. A biocompatible patch and uses thereof for treating a damaged cardiac tissue. |
| FILED | Thursday, June 03, 2021 |
| APPL NO | 18/007918 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/48 (20130101) Original (OR) Class A61L 27/54 (20130101) A61L 2300/414 (20130101) A61L 2400/12 (20130101) A61L 2430/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226334 | McAllister et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Devin McAllister (Marietta, Georgia); Mark R. Prausnitz (Atlanta, Georgia); Sebastien Henry (Smyrna, Georgia); James J. Norman (North Bethesda, Maryland) |
| ABSTRACT | Microneedle patches and systems, and methods for use of such patches and systems. In one aspect, a microneedle patch is provided including a tab portion for handling the microneedle patch. In another aspect, a system is provided including a microneedle patch and a tray for housing the microneedle patch. In still another aspect, various indicators providing for providing feedback prior to, during, and after administration of the microneedle patch are provided. Advantageously, the described microneedle patches and systems provide improved handling and ease of application of the microneedle patches to skin for the delivery of therapeutic agents. |
| FILED | Monday, February 27, 2023 |
| APPL NO | 18/114866 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/0015 (20130101) Original (OR) Class A61M 2037/0023 (20130101) A61M 2037/0046 (20130101) A61M 2037/0061 (20130101) A61M 2205/581 (20130101) A61M 2205/582 (20130101) A61M 2205/583 (20130101) A61M 2205/586 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226493 | MONTGOMERY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cellphire, Inc. (Rockville, Maryland) |
| ASSIGNEE(S) | Cellphire, Inc. (Rockville, Maryland) |
| INVENTOR(S) | Joshua Donald MONTGOMERY (Silver Spring, Maryland); Braden Carl ISHLER (Montgomery Village, Maryland); Stephen Edward AMOS (Buckeystown, Maryland); Keith Andrew MOSKOWITZ (Westfield, Indiana); Amber Nicole LEE (Montgomery Village, Maryland); Rafael JORDA (Merignac, France); Glen Michael FITZPATRICK (North Potomac, Maryland); Michael Alexander MATHEWS (Arlington, Virginia) |
| ABSTRACT | Provided herein are materials and methods for the preparation of blood products. In one aspect, provided herein is a composition including platelets or platelet derivatives and an aqueous medium, wherein the aqueous medium has a protein concentration less than 50% of the protein concentration of donor apheresis plasma. |
| FILED | Wednesday, November 16, 2022 |
| APPL NO | 18/056220 |
| CURRENT CPC | Separation B01D 61/14 (20130101) Original (OR) Class B01D 2311/12 (20130101) B01D 2315/10 (20130101) B01D 2315/16 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0644 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227439 | RINEHART et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (NEW HAVEN, Connecticut); MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (ROCHESTER, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jesse RINEHART (Guilford, Connecticut); Farren ISAACS (Stamford, Connecticut); Andre LEVCHENKO (Madison, Connecticut); Denton HOYER (West Haven, Connecticut); Apiwat WANGWEERAWONG (Bedford, Massachusetts); William HUNGERFORD (Kenneth City, Florida); Mark PLUMMER (Westbrook, Connecticut); Alfredo QUINONES-HINOJOSA (Ponte Vedra Beach, Florida); Paula Valentina SCHIAPPARELLI (Ponte Vedra Beach, Florida) |
| ABSTRACT | The present disclosure provides SPAK/OSR inhibitors. In certain embodiments, the compounds of the disclosure can be used to treat, ameliorate, and/or prevent certain cancers in a subject. |
| FILED | Friday, December 04, 2020 |
| APPL NO | 17/756890 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 239/48 (20130101) C07D 403/12 (20130101) C07D 413/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227443 | Barbosa |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GB006, INC. (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Antonio J. Barbosa (Ave Maria, Florida) |
| ABSTRACT | The present invention provides new salts and crystalline forms of leukadherin LA1 [(Z)-4-(5-((3-benzyl-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-yl)benzoic acid] according to Formula I. Methods for preparation of the salts and crystalline forms are also described, as well as methods for treating β2 integrin-mediated diseases and conditions using the salts and crystalline forms. |
| FILED | Tuesday, November 01, 2022 |
| APPL NO | 17/978848 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/13 (20130101) Acyclic or Carbocyclic Compounds C07C 215/08 (20130101) Heterocyclic Compounds C07D 417/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227452 | MILLER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | The University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Courtney Anne MILLER (Jupiter, Florida); Patrick Robert GRIFFIN (Jupiter, Florida); Theodore Mark KAMENECKA (Palm Beach Gardens, Florida); Gavin Rumbaugh (Jupiter, Florida); Matthew Surman (Albany, New York); Steve Young (Lansdale, Pennsylvania); Steven Duddy (Ann Arbor, Michigan); Laszlo Radnai (East Palm Beach Gardens, Florida) |
| ABSTRACT | The invention can provide compounds, analogs of blebbistatin, effective and selective inhibitors of nonmuscle myosin II relative to cardiac myosin II. Compounds can be used in the method of treating a disease, disorder, or medical condition in a patient, comprising modulating myosin II ATPase, such as treatment of substance abuse relapse disorder, or of renal disease, cancer and metastasis, benign prostate hyperplasia, hemostasis or thrombosis, nerve injury including retinal damage, lung fibrosis, liver fibrosis, arthrofibrosis, wound healing, spinal cord injury, periodontitis, glaucoma and immune-related diseases including multiple sclerosis; or wherein the disease, disorder, or medical condition comprises addiction including abuse of or addiction to anything classified as a Substance-Related or Addictive Disorder in the Diagnostic and Statistical Manual of Mental Disorders (DSM), such as, but not limited to, cocaine, opioids, amphetamines, ethanol, cannabis/marijuana, nicotine, and activities including gambling. Compounds are of general formula with substituents as defined herein. |
| FILED | Wednesday, February 15, 2023 |
| APPL NO | 18/169660 |
| CURRENT CPC | Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class C07D 471/14 (20130101) C07D 495/14 (20130101) C07D 519/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227476 | XUE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Fengtian XUE (Potomac, Maryland); Angela WILKS (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Fengtian XUE (Potomac, Maryland); Angela WILKS (Baltimore, Maryland) |
| ABSTRACT | Gallium-salophen compounds, and methods of using the same for the treatment of disease are disclosed. |
| FILED | Friday, June 04, 2021 |
| APPL NO | 18/000802 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/003 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227492 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The USA as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); Ash Stevens, LLC (Detroit, Michigan) |
| ASSIGNEE(S) | The USA as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); Ash Stevens, LLC (Detroit, Michigan) |
| INVENTOR(S) | Min Lee (San Diego, California); Diana Blithe (Silver Spring, Maryland); Ming-Teh Lin (Farmington Hills, Michigan); Pranab Gupta (West Bloomfield, Michigan); Bashir Kaskar (Troy, Michigan) |
| ABSTRACT | Disclosed herein are monomeric and oligomeric compound embodiments for use as contraceptive agents. Monomeric compound embodiments disclosed herein comprise substituents that facilitate the ability of the compounds to exhibit progestogenic, androgenic, and estrogenic activity, which can prevent or inhibit bone density loss in subjects. Oligomeric compound embodiments disclosed herein provide the ability to control receptor activation and/or treatment by incorporating a tunable linker group which couples steroidal-based compounds to one another or with therapeutic agents and facilitates selective cleavage of the monomeric components of the oligomeric compound. |
| FILED | Thursday, June 10, 2021 |
| APPL NO | 18/009571 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 15/16 (20180101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/05 (20130101) Steroids C07J 1/0074 (20130101) C07J 1/0096 (20130101) C07J 43/003 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227512 | Kwong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Servic (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Servic (, None) |
| INVENTOR(S) | Peter Kwong (Washington, District of Columbia); Marie Pancera (Seattle, Washington); Tongqing Zhou (Boyds, Maryland); Ivelin Georgiev (Nashville, Tennessee); Michael Gordon Joyce (Washington, District of Columbia); Priyamvada Acharya (Chapel Hill, North Carolina); Jason Gorman (Washington, District of Columbia); Yongping Yang (Potomac, Maryland); Guillaume Stewart-Jones (Cambridge, Massachusetts); Rita Chen (St. Louis, Missouri); Gwo-Yu Chuang (Rockville, Maryland); John Mascola (Rockville, Maryland); Baoshan Zhang (Bethesda, Maryland); Cheng Cheng (Bethesda, Maryland); Mallika Sastry (Rockville, Maryland); Aliaksandr Druz (Germantown, Maryland) |
| ABSTRACT | HIV-1 Env ectodomain trimers stabilized in a prefusion mature closed conformation and methods of their use and production are disclosed. In several embodiments, the HIV-1 Env ectodomain trimers and/or nucleic acid molecules can be used to generate an immune response to HIV-1 in a subject. In additional embodiments, the therapeutically effective amount of the HIV-1 Env ectodomain trimers can be administered to a subject in a method of treating or preventing HIV-1 infection. |
| FILED | Monday, October 03, 2022 |
| APPL NO | 17/937719 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) A61K 2039/55555 (20130101) Peptides C07K 14/005 (20130101) C07K 14/435 (20130101) Original (OR) Class C07K 16/1063 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56988 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227523 | Cochran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jennifer R. Cochran (Stanford, California); Douglas S. Jones (Newton, Massachusetts); Mihalis S. Kariolis (San Mateo, California); Ping-Chuan Tsai (Fremont, California) |
| ABSTRACT | The present disclosure presents a general approach to engineering existing protein-protein interactions through domain addition and evolution. The disclosure teaches the creation of novel fusion proteins that include knottin peptides where a portion of the knottin peptide is replaced with a sequence that has been created for binding to a particular target. Such fusion proteins can also be bispecific or multi specific in that they can bind to and/or inhibit two or more receptors or receptor ligands. Knottins may be fused with an existing ligand (or receptor) as a general platform tor increasing the affinity of a ligand-receptor interaction or for creating a multi specific protein. In addition, the fusion proteins may comprise a knottin peptide fused to another protein where the other protein facilitates proper expression and folding of the knottin. |
| FILED | Monday, November 14, 2022 |
| APPL NO | 18/055297 |
| CURRENT CPC | Peptides C07K 14/47 (20130101) C07K 14/71 (20130101) C07K 14/81 (20130101) C07K 14/475 (20130101) C07K 14/705 (20130101) Original (OR) Class C07K 14/4702 (20130101) C07K 14/8121 (20130101) C07K 14/43518 (20130101) C07K 2319/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227537 | SCHEPENS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VIB VZW (Gent, Belgium); UNIVERSITEIT GENT (Gent, Belgium); BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN (Bethesda, Maryland); TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire); KATHOLIEKE UNIVERSITEIT LEUVEN, K.U.LEUVEN R and D (Leuven, Belgium); EXEVIR BIO BV (Gent, Belgium); VRIJE UNIVERSITEIT BRUSSEL (Brussel, Belgium) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bert SCHEPENS (Drongen, Belgium); Xavier SAELENS (leper, Belgium); Nico CALLEWAERT (Nevele, Belgium); Dorien DE VLIEGER (Lotenhulle, Belgium); Loes VAN SCHIE (Gent, Belgium); Wim NERINCKX (Astene, Belgium); Kenny ROOSE (Gent, Belgium); Wander VAN BREEDAM (Antwerpen, Belgium); Hannah EECKHAUT (Oosterzele, Belgium); Daria FIJALKOWSKA (Evergem, Belgium); Chiara LONIGRO (Gent, Belgium); Sieglinde DE CAE (Lennik, Belgium); Bruno DOMBRECHT (Heusden, Belgium); Catelijne STORTELERS (Gent, Belgium); Johan NEYTS (Kessel-Lo, Belgium); Leen DELANG (Korbeek-Lo, Belgium); Suzanne KAPTEIN (DH Maastricht, Netherlands); Joana DUARTE DA ROCHA PEREIRA (Sint- Agatha-Rode, Belgium); Barney GRAHAM (Rockville, Maryland); Jason MCLELLAN (Austin, Texas); Daniel WRAPP (Chandler, Arizona); Han REMAUT (Roosbeek, Belgium) |
| ABSTRACT | The present invention relates to the field of virology, more specifically to the field of zoonotic Coronaviruses. Specifically, the invention provides for binding agents specific for the spike protein receptor binding domain (RBD) of the SARS-Corona virus, more specifically for an epitope of the RBD present in a broad range of Sarbecoviruses and mutants thereof, even more specifically present in SARS-Cov and SARS-CoV-2 viruses. More specifically, the invention relates to compositions comprising antibodies capable of specifically binding and neutralizing SARS-Corona viruses. More specifically the invention relates to compositions comprising single domain antibodies, or specifically VHHs, and compositions comprising multivalent binding agents comprising IgG Fc fusions thereof, specifically VHH-Fc fusions thereof, even more specifically comprising heavy chain only VHH72-S56A-IgG1-Fc fusions, or compositions comprising any humanized form of any one thereof, and are capable of specifically binding and neutralizing SARS-Corona viruses, specifically SARS-Cov-2 virus. The compositions are useful in the diagnosis of Sarbecoviruses, and specifically SARS-CoV-2 virus, and in prophylactic and/or therapeutic treatment of a condition resulting from infections with Sarbecoviruses, specifically SARS-Corona or SARS-CoV-2 virus, or mutants thereof. |
| FILED | Friday, February 05, 2021 |
| APPL NO | 17/760300 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/10 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227546 | Petri, JR. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | William A. Petri, JR. (Charlottesville, Virginia); Alexandra N. Donlan (Charlottesville, Virginia); Mary Katherine Young (Charlottesville, Virginia); Mayuresh M. Abhyankar (Charlottesville, Virginia); Barbara J. Mann (Charlottesville, Virginia) |
| ABSTRACT | Methods for treating coronavirus disease 2019 (COVID-19), the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, is described. The methods can be used to reduce the severity of outcomes related to COVID-19, such as hospitalization and ventilation. For example, treatment of a subject with a therapeutic agent that neutralizes interleukin 13 (IL-13) can result in reduced risk for mechanical ventilation in the subject. Also described are methods of predicting risk of mechanical ventilation in subjects with COVID-19. |
| FILED | Thursday, June 17, 2021 |
| APPL NO | 18/011412 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) Peptides C07K 16/247 (20130101) Original (OR) Class C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6869 (20130101) G01N 2333/50 (20130101) G01N 2333/165 (20130101) G01N 2333/523 (20130101) G01N 2333/5412 (20130101) G01N 2333/5418 (20130101) G01N 2333/5421 (20130101) G01N 2333/5437 (20130101) G01N 2800/56 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227549 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CITY OF HOPE (Duarte, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jianhua Yu (Duarte, California); Michael A. Caligiuri (Duarte, California) |
| ABSTRACT | Provided herein, inter alia, are compositions and methods including recombinant oncolytic viruses expressing CD47 antibody for the treatment of diseases including cancer, immune disorders, and infectious disease. |
| FILED | Saturday, February 06, 2021 |
| APPL NO | 17/797681 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/502 (20130101) A61K 35/763 (20130101) A61K 39/001111 (20180801) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 15/08 (20180101) A61P 35/00 (20180101) A61P 37/04 (20180101) Peptides C07K 16/2803 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/52 (20130101) C07K 2317/73 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2710/16632 (20130101) C12N 2710/16643 (20130101) C12N 2710/16662 (20130101) C12N 2710/16671 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227571 | Song et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Wenchao Song (Bryn Mawr, Pennsylvania); Sayaka Sato (Philadelphia, Pennsylvania); Takashi Miwa (Bala Cynwyd, Pennsylvania); Damodar Gullipalli (Philadelphia, Pennsylvania) |
| ABSTRACT | This invention relates to inhibition of the complement signaling using an anti-C5 antibody. Specifically, the invention relates to methods of treating a complement-mediated disease or complement-mediated disorder in an individual by contacting the individual with an anti-C5 antibody. |
| FILED | Thursday, January 12, 2023 |
| APPL NO | 18/153720 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/2896 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/55 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227574 | Liu |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Bin Liu (San Francisco, California) |
| ABSTRACT | Methods are provided for identifying and selecting antibodies that are internalized into cells via the macropinocytosis pathway. Additionally antibodies that are internalized via this pathway are provided as well as immunoconjugates comprising such antibodies. |
| FILED | Wednesday, August 03, 2022 |
| APPL NO | 17/880556 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 47/6801 (20170801) A61K 47/6851 (20170801) A61K 47/6889 (20170801) A61K 49/00 (20130101) Peptides C07K 16/005 (20130101) C07K 16/30 (20130101) Original (OR) Class C07K 16/2866 (20130101) C07K 16/3069 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1037 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/6854 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227583 | QUIJANO et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Elias QUIJANO (Durham, Connecticut); Peter GLAZER (Guilford, Connecticut) |
| ABSTRACT | Compositions and methods of use thereof for delivering nucleic acid cargo into cells are provided. The compositions typically include (a) a 3E10 monoclonal antibody or an antigen binding, cell-penetrating fragment thereof; a monovalent, divalent, or multivalent single chain variable fragment (scFv); or a diabody; or humanized form or variant thereof, and (b) a nucleic acid cargo including, for example, a nucleic acid encoding a polypeptide, a functional nucleic acid, a nucleic acid encoding a functional nucleic acid, or a combination thereof. Elements (a) and (b) are typically non-covalently linked to form a complex. |
| FILED | Monday, August 31, 2020 |
| APPL NO | 17/638642 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0025 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/44 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/77 (20130101) C07K 2317/565 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2310/3181 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227782 | DALEY |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | George Q. DALEY (Cambridge, Massachusetts) |
| ABSTRACT | Embodiments herein relate to in vitro production methods of hematopoietic stem cell (HSC) and hematopoietic stem and progenitor cell (HSPC) that have long-term multilineage hematopoiesis potentials upon in vivo engraftment. The HSC and HSPCs are derived from pluripotent stem cells-derived hemogenic endothelia cells (HE) by non-integrative episomal vectors-based gene transfer. |
| FILED | Wednesday, December 28, 2022 |
| APPL NO | 18/147554 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0647 (20130101) Original (OR) Class C12N 2500/24 (20130101) C12N 2500/38 (20130101) C12N 2500/44 (20130101) C12N 2501/14 (20130101) C12N 2501/15 (20130101) C12N 2501/26 (20130101) C12N 2501/32 (20130101) C12N 2501/41 (20130101) C12N 2501/105 (20130101) C12N 2501/115 (20130101) C12N 2501/125 (20130101) C12N 2501/145 (20130101) C12N 2501/165 (20130101) C12N 2501/602 (20130101) C12N 2501/603 (20130101) C12N 2501/604 (20130101) C12N 2501/605 (20130101) C12N 2501/606 (20130101) C12N 2501/608 (20130101) C12N 2501/2303 (20130101) C12N 2501/2306 (20130101) C12N 2501/2311 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227793 | Joung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, None); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | J. Keith Joung (Winchester, Massachusetts); Peter Cabeceiras (Boston, Massachusetts) |
| ABSTRACT | Enhanced virus-like particles (eVLPs), comprising a membrane comprising a phospholipid bilayer with one or more virally-derived glycoproteins on the external side; and a cargo disposed in the core of the eVLP on the inside of the membrane, wherein the eVLP does not comprise an exogenous gag/pol protein, and methods of use thereof for delivery of the cargo to cells. |
| FILED | Monday, January 23, 2023 |
| APPL NO | 18/158173 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 2310/20 (20170501) C12N 2760/20223 (20130101) C12N 2760/20252 (20130101) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227796 | STONE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Everett STONE (Austin, Texas); Donjeta GJUKA (Austin, Texas) |
| ABSTRACT | Methods and compositions related to the engineering of a protein with MTA/ADO-degrading enzyme activity are described. For example, in certain aspects there may be disclosed an MTase capable of degrading MTA/ADO. Furthermore, certain aspects of the invention provide compositions and methods for the treatment of cancer or SCID with an MTase using the disclosed proteins or nucleic acids. |
| FILED | Thursday, November 10, 2022 |
| APPL NO | 18/054347 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/45 (20130101) A61K 39/3955 (20130101) A61K 47/60 (20170801) A61K 47/6849 (20170801) A61K 47/6851 (20170801) A61K 47/6855 (20170801) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) A61P 35/04 (20180101) Peptides C07K 16/2818 (20130101) C07K 2317/76 (20130101) C07K 2317/622 (20130101) C07K 2319/30 (20130101) C07K 2319/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/96 (20130101) C12N 9/1077 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) Enzymes C12Y 204/02028 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) G01N 33/574 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227809 | Ruan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Jackson Laboratory (Bar Harbor, Maine) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yijun Ruan (Farmington, Connecticut) |
| ABSTRACT | The scChIA-Drop method is a microfluidics-based dual-indexing strategy for single-cell and single-molecule chromatin interaction analysis. |
| FILED | Tuesday, July 20, 2021 |
| APPL NO | 18/007129 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227813 | Ren et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ludwig Institute for Cancer Research Ltd (Zurich, Switzerland) |
| ASSIGNEE(S) | Ludwig Institute for Cancer Research Ltd (Zurich, Switzerland) |
| INVENTOR(S) | Bing Ren (La Jolla, California); Chenxu Zhu (La Jolla, California) |
| ABSTRACT | The present invention relates to methods for the joint analysis of regulation of gene expression and gene expression in single cells. Provided are methods for obtaining gene expression information for a single nucleus, the methods comprising deriving a DNA library from the genomic DNA in one or more nuclei and deriving an RNA library from the RNA in one or more nuclei, sequencing the molecules in the RNA library and the DNA library, and correlating the RNA library and the DNA library for each of the one or more nuclei. |
| FILED | Tuesday, June 22, 2021 |
| APPL NO | 18/001898 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1072 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227848 | CURIEL et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | DAVID CURIEL (St. Louis, Missouri); Michael Diamond (St. Louis, Missouri); IGOR DMITRIEV (St. Louis, Missouri); Ahmed Hassan (St. Louis, Missouri) |
| ABSTRACT | Compositions and methods for treating a viral infection may comprise use of an adenoviral vector. An adenoviral vector of the present disclosure may comprise a non-human adenoviral genome with one or more gene locus functionally removed and a transgene. A method of treating a viral infection may comprise administering a composition comprising an adenoviral vector of the present disclosure, to a subject and reducing the infectivity or transmission of the virus. Intranasal administration provides enhance protection of the upper respiratory tract of a subject relative to intramuscular administration. |
| FILED | Tuesday, June 01, 2021 |
| APPL NO | 18/007677 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/04 (20180101) Peptides C07K 14/165 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2710/10343 (20130101) C12N 2770/20022 (20130101) C12N 2770/20034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227859 | Doudna et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Emmanuelle Charpentier (Berlin, Germany); The Regents of the University of California (Oakland, California); University of Vienna (Vienna, Austria) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jennifer A. Doudna (Berkeley, California); Martin Jinek (Berkeley, California); Krzysztof Chylinski (Vienna, Austria); Emmanuelle Charpentier (Berlin, Germany) |
| ABSTRACT | The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a polypeptide associated with the target DNA. The present disclosure further provides site-specific modifying polypeptides. The present disclosure further provides methods of site-specific modification of a target DNA and/or a polypeptide associated with the target DNA The present disclosure provides methods of modulating transcription of a target nucleic acid in a target cell, generally involving contacting the target nucleic acid with an enzymatically inactive Cas9 polypeptide and a DNA-targeting RNA. Kits and compositions for carrying out the methods are also provided. The present disclosure provides genetically modified cells that produce Cas9; and Cas9 transgenic non-human multicellular organisms. |
| FILED | Thursday, November 10, 2022 |
| APPL NO | 18/054538 |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 6/4684 (20180501) Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/027 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/465 (20130101) A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/63 (20130101) C12N 15/70 (20130101) C12N 15/90 (20130101) C12N 15/102 (20130101) C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 15/746 (20130101) C12N 15/902 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/13 (20130101) C12N 2310/20 (20170501) C12N 2310/531 (20130101) C12N 2310/3519 (20130101) C12N 2800/80 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Enzymes C12Y 301/04 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02312 (20130101) H01L 33/0075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227888 | KIM et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GoDx, Inc. (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chang Hee KIM (Waunakee, Wisconsin); Jacob Jerome TOKAR (Madison, Wisconsin); Xiao JIANG (Madison, Wisconsin) |
| ABSTRACT | The present invention provides point-of-need diagnostic devices and kits for detecting a target nucleic acid sequence in a sample. Methods of using the point-of-need diagnostic devices or the kits disclosed are also provided. |
| FILED | Wednesday, May 12, 2021 |
| APPL NO | 17/925223 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5023 (20130101) B01L 3/502715 (20130101) B01L 2200/16 (20130101) B01L 2200/0621 (20130101) B01L 2300/18 (20130101) B01L 2300/025 (20130101) B01L 2300/087 (20130101) B01L 2300/0627 (20130101) B01L 2300/0681 (20130101) B01L 2400/043 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227891 | Seelig et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Georg Seelig (Seattle, Washington); Richard Muscat (London, United Kingdom); Alexander B. Rosenberg (Seattle, Washington) |
| ABSTRACT | Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens. |
| FILED | Tuesday, January 24, 2023 |
| APPL NO | 18/158487 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6855 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227895 | Church et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | George M. Church (Brookline, Massachusetts); Je-Hyuk Lee (Allston, Massachusetts); Evan R. Daugharthy (Cambridge, Massachusetts) |
| ABSTRACT | Methods of labelling one or more subcellular components (e.g., an organelle and/or subcellular region) in vivo are provided. Methods of labelling a protein in vivo are provided. Methods of determining a nucleic acid sequence in situ are also provided. |
| FILED | Friday, January 20, 2023 |
| APPL NO | 18/157108 |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) C07H 21/04 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6841 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227901 | Abate et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Adam R. Abate (Daly City, California); Iain Clark (San Francisco, California); Peng Xu (Redwood City, California); Cyrus Modavi (San Francisco, California) |
| ABSTRACT | Methods for selectively adding one or more reagents are provided. In certain aspects, the methods include selectively merging one or more droplets of a plurality of droplets with one or more droplets of a plurality of reagent droplets based on detection of a property. Systems, devices and kits for practicing the subject methods are also provided. The subject disclosure may find use in a wide variety of applications, such as increasing the accuracy and/or efficiency of single-cell sequencing, detection of cancer or other diseases, monitoring disease progression, analyzing the DNA or RNA content of cells, and other applications in which it is desired to detect and/or quantify specific target cells. |
| FILED | Thursday, June 24, 2021 |
| APPL NO | 18/010188 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502792 (20130101) B01L 2200/16 (20130101) B01L 2200/0652 (20130101) B01L 2300/0645 (20130101) B01L 2300/0654 (20130101) B01L 2300/0867 (20130101) B01L 2400/0427 (20130101) B01L 2400/0622 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227911 | Khatri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Purvesh Khatri (Menlo Park, California); Timothy E. Sweeney (San Francisco, California) |
| ABSTRACT | Methods for diagnosis of sepsis are disclosed. In particular, the invention relates to the use of bio -markers for aiding diagnosis, prognosis, and treatment of sepsis, and to a panel of biomarkers that can be used to distinguish sepsis from noninfectious sources of inflammation, such as caused by traumatic injury, surgery, autoimmune disease, thrombosis, or systemic inflammatory response syndrome (SIRS). |
| FILED | Wednesday, March 08, 2023 |
| APPL NO | 18/180833 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/00 (20190201) G16B 25/10 (20190201) G16B 25/20 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) Technologies for Adaptation to Climate Change Y02A 90/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230228653 | Kaushansky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Seattle Children's Hospital d/b/a Seattle Children's Research Institute (Seattle, Washington) |
| ASSIGNEE(S) | Seattle Children's Hospital d/b/a Seattle Children's Research Institute (Seattle, Washington) |
| INVENTOR(S) | Alexis Kaushansky (Seattle, Washington); Brian Zephyr Pitre (Seattle, Washington); Tess Seltzer (Seattle, Washington); Christopher Sutanto (Seattle, Washington); Samantha Brown (Seattle, Washington); Thurston Herricks (Seattle, Washington) |
| ABSTRACT | Systems, apparatuses, and methods enable rapid, repeatable, and accurate dissection of arthropods. Arthropod dissection apparatuses includes a shear dissection mechanism having a primary shear body and a secondary shear body. The primary shear body includes at least an inlet channel, a first outlet channel, and a second outlet channel formed therein. The secondary shear body is disposed in an aperture of the primary shear body and has a dissection chamber formed therein. The secondary shear body is movable between a first position and a second position relative to the primary shear body, which causes a shearing action at a shearing interface between the secondary shear body and the primary shear body. |
| FILED | Friday, May 14, 2021 |
| APPL NO | 17/997909 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/286 (20130101) Original (OR) Class G01N 2001/2866 (20130101) G01N 2001/2873 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230228683 | Butte et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pramod Butte (Studio City, California); Paul Lapchak (San Diego, California); David Scott Kittle (Running Springs, California) |
| ABSTRACT | The invention provides systems for characterizing a biological sample by analyzing emission of fluorescent light from the biological sample upon excitation and methods for using the same. The system includes a laser source, collection fibers, a demultiplexer and an optical delay device. All references cited herein are incorporated by reference in their entirety as though fully set forth. Unless defined otherwise, technical and scientific terms used herein have the same meaning as commonly understood by one of-ordinary skill in the art in which this invention belongs. |
| FILED | Thursday, July 21, 2022 |
| APPL NO | 17/870090 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0071 (20130101) A61B 5/0084 (20130101) A61B 5/14556 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/0218 (20130101) G01J 3/2889 (20130101) G01J 3/4406 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/64 (20130101) G01N 21/645 (20130101) G01N 21/6402 (20130101) G01N 21/6408 (20130101) G01N 21/6428 (20130101) G01N 21/6486 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230228695 | Gonen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tamir Gonen (Los Angeles, California); Michael Martynowycz (Los Angeles, California) |
| ABSTRACT | Methods of introducing a small molecule into a crystal of a macromolecule, of obtaining a microcrystal having a macromolecule and a small molecule from a crystal of the macromolecule, of determining a structural model for a complex having a macromolecule and a small molecule, of identifying a small molecule that complexes with a macromolecule, and of screening a library of small molecules for their binding to a macromolecule are disclosed. |
| FILED | Friday, May 21, 2021 |
| APPL NO | 17/926955 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/2055 (20130101) Original (OR) Class G01N 23/20025 (20130101) G01N 2223/60 (20130101) G01N 2223/3306 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/28 (20130101) H01J 37/305 (20130101) H01J 2237/2001 (20130101) H01J 2237/31749 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230228715 | Stegemann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jan P. Stegemann (Ann Arbor, Michigan); Cheri X. Deng (Ann Arbor, Michigan); Eric C. Hobson (Ann Arbor, Michigan) |
| ABSTRACT | Techniques for performing an acoustic rheology measurement of a sample are provided. A first set of acoustic pulses is provided by a focused ultrasound transducer to induce surface oscillations of the sample. A second set of acoustic pulses is provided by a detection transducer to interrogate the sample and detect the echo pulses reflected by the sample surface as a function of time. The detection ultrasound transducer system converts the echo signals to an electrical signal associated with the detected echo pulses, and a processor determines a dynamic displacement of the interface of the sample as a function of time. The processor also determines the spectrum, resonant surface oscillation frequency, and damping coefficient. Viscoelastic properties of the material are determined from these measurements, with applications for the characterization of the blood clotting process, the identification of a blood clot, gelation process, tumor, or fibrosis based on the viscoelastic properties. |
| FILED | Friday, January 13, 2023 |
| APPL NO | 18/154348 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/02 (20130101) Original (OR) Class G01N 29/04 (20130101) G01N 33/02 (20130101) G01N 33/487 (20130101) G01N 33/4833 (20130101) G01N 2291/022 (20130101) G01N 2291/023 (20130101) G01N 2291/106 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230228737 | Jackson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Meyer Jackson (Madison, Wisconsin); Masoud Sepehri Rad (Madison, Wisconsin) |
| ABSTRACT | As described herein, a hybrid voltage sensor genetically-encoded voltage indicator (GEVI) for mitochondria or endoplasmic reticulum includes a transmembrane domain, and a fluorescent protein, wherein a terminus of the transmembrane domain and a terminus of the fluorescent protein are covalently linked directly or by a linker comprising 1 to 20 amino acids, and wherein the transmembrane domain comprises SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4 or a peptide with greater than 85%, 90%, 95% or 98% identity to SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3 or SEQ ID NO: 4. Also described are expression vectors, expression cassettes, and organelle membranes, as well as methods of determining the voltage across an organelle using the GEVIs. |
| FILED | Tuesday, August 23, 2022 |
| APPL NO | 17/893530 |
| CURRENT CPC | Peptides C07K 14/705 (20130101) C07K 2319/03 (20130101) C07K 2319/60 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0071 (20130101) Enzymes C12Y 114/14001 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) Original (OR) Class G01N 33/5076 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230228738 | Dong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xinzhong Dong (Clarksville, Maryland); Chirag Vasavda (Baltimore, Maryland); Solomon H. Snyder (Baltimore, Maryland); James Meixiong (Baltimore, Maryland); Yingying Cheng (Baltimore, Maryland); Nathachit Limjunyawong (Baltimore, Maryland); Xintong Dong (Baltimore, Maryland) |
| ABSTRACT | The present invention relates to cells and methods for detecting compounds that affect G protein coupled receptor mediated conditions. The invention also relates to methods for treating adverse drug reactions, autoimmune disorders, and pruritus. |
| FILED | Monday, June 27, 2022 |
| APPL NO | 17/850169 |
| CURRENT CPC | Peptides C07K 14/723 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/64 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/15 (20130101) G01N 33/74 (20130101) G01N 33/5041 (20130101) Original (OR) Class G01N 2333/726 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230228763 | Kelleher |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Neil Lindstrom Kelleher (Evanston, Illinois) |
| ABSTRACT | Disclosed herein are methods for the direct readout of proteoforms and complexes thereof, such as immunoglobulins. The method may comprise ionizing a sample with an ionizer, wherein the sample comprises a mixture of different proteoforms or complexes thereof; detecting a multiplicity of ions generated by the ionization of the sample with a current detector; determining ion masses for each of the multiplicity of ions detected with the current detector with a mass analyzer; generating a mass-domain spectrum from the ion masses with the mass analyzer. The method may also comprise determining one or more metrics capturing the heterogeneity or relative abundance of proteoforms. |
| FILED | Friday, June 18, 2021 |
| APPL NO | 18/002457 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6848 (20130101) G01N 33/6854 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230228831 | Sylvester et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NOUS Imaging, Inc. (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chad Sylvester (St. Louis, Missouri); Deanna Greene (St. Louis, Missouri); Scott Marek (St. Louis, Missouri); Scott Norris (St. Louis, Missouri); Jared Roland (St. Louis, Missouri); Evan Gordon (St. Louis, Missouri); Timothy Laumann (St. Louis, Missouri); Damien Fair (St. Louis, Missouri); Kenneth Bruener (St. Louis, Missouri); Nico Dosenbach (St. Louis, Missouri) |
| ABSTRACT | A method of performing personalized neuromodulation on a subject is provided. The method includes acquiring functional magnetic resonance imaging (fMRI) data of a brain of the subject. The method also includes calculating functional connectivity of the brain between a voxel in a subcortical region of the brain and a voxel in a cortical region of the brain, based on the fMRI data. The method also includes identifying a target location in the brain to be targeted by neuromodulation based on the calculated functional connectivity. |
| FILED | Thursday, January 19, 2023 |
| APPL NO | 18/098886 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0036 (20180801) A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 5/4064 (20130101) A61B 2576/026 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/3727 (20130101) A61N 1/36189 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4806 (20130101) Original (OR) Class G01R 33/56366 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230230249 | WANG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Shaopeng WANG (Chandler, Arizona); Fenni ZHANG (Tempe, Arizona); Nongjian TAO (Fountain Hills, Arizona) |
| ABSTRACT | Detecting single bacterial cells in a sample includes collecting, from a sample provided to an imaging apparatus, a multiplicity of images of the sample over a length of time; assessing a trajectory of each bacterial cell in the sample; and assessing, based on the trajectory of each bacterial cell in the sample, a number of bacterial cell divisions that occur in the sample during the length of time. |
| FILED | Wednesday, June 23, 2021 |
| APPL NO | 18/002438 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 41/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/06 (20130101) C12Q 1/18 (20130101) Image Data Processing or Generation, in General G06T 7/0016 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230230636 | GU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Curator's of the University of Missouri (Columbia, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Li-Qun GU (Columbia, Missouri); Kai TIAN (Columbia, Missouri) |
| ABSTRACT | The present disclosure relates to methods of writing data in nucleic acid chains and methods of reading data written in nucleic acid chains. The present disclosure also relates to a kit for writing and reading data in nucleic acid chains. |
| FILED | Friday, May 14, 2021 |
| APPL NO | 17/998269 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/48721 (20130101) Static Stores G11C 13/0019 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230230655 | McGovern et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CEDARS-SINAI MEDICAL CENTER (LOS ANGELES, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dermot P. McGovern (Los Angeles, California); Dalin Li (Walnut, California) |
| ABSTRACT | The present disclosure provides methods and systems of identifying a fibrotic disease in a subject using a DeepLearning model. The DeepLearning model may be used to predict, treat, monitor, and/or prevent the fibrotic disease in the subject, as well as to characterize a subtype of the fibrotic disease. |
| FILED | Friday, October 28, 2022 |
| APPL NO | 18/050837 |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) Original (OR) Class G16B 30/00 (20190201) G16B 40/20 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230230657 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | HoJoon Lee (Palo Alto, California); Hanlee P. Ji (Stanford, California); Tsachy Weissman (Stanford, California); Dmitri Pavlichin (Redwood City, California) |
| ABSTRACT | Systems and methods of storing and retrieving K-mer data in a data structure are provided. In certain embodiments, the K-mer data is stored as an integer value that defines an address of a slot in the data structure. In many embodiments, each slot in the data structure stores the remaining portion of the K-mer that is not part of the prefix. Additional embodiments are directed to genetic or genomic analysis using a data structure for storing K-mer data. |
| FILED | Monday, September 21, 2020 |
| APPL NO | 17/754017 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0604 (20130101) G06F 3/0655 (20130101) G06F 3/0673 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/40 (20190201) G16B 30/00 (20190201) Original (OR) Class G16B 45/00 (20190201) G16B 50/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230230680 | Ward et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kevin Ward (Glen Allen, Virginia); Daniel Francis Taylor (Belleville, Michigan); Michael W. Sjoding (Ann Arbor, Michigan); Christopher Elliot Gillies (Ann Arbor, Michigan) |
| ABSTRACT | A computing system includes a processor; and a memory having stored thereon an adjustment application comprising computer-executable instructions that, when executed, cause the computing system to: display a graphical user interface including a digital medical image of a patient; superimpose a bounding box; receive an adjustment of an area of interest; and provide an adjusted digital medical image. A non-transitory computer-readable medium includes computer-executable instructions that, when executed via one or more processors, cause a computer to: display a graphical user interface including a digital medical image of a patient; superimpose a bounding box; receive an adjustment of an area of interest; and provide an adjusted digital medical image. A computer-implemented method includes: displaying a graphical user interface including a digital medical image of a patient; superimposing a bounding box; receiving an adjustment of an area of interest; and providing an adjusted digital medical image. |
| FILED | Tuesday, March 07, 2023 |
| APPL NO | 18/180119 |
| CURRENT CPC | Electric Digital Data Processing G06F 17/18 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 11/20 (20130101) G06T 2207/10116 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30061 (20130101) G06T 2210/12 (20130101) Image or Video Recognition or Understanding G06V 10/25 (20220101) G06V 10/82 (20220101) G06V 10/454 (20220101) G06V 10/987 (20220101) G06V 10/7784 (20220101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 30/40 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230230827 | Ouyang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zheng Ouyang (West Lafayette, Indiana); Yue Ren (West Lafayette, India); Ziqing Lin (West Lafayette, Indiana) |
| ABSTRACT | The invention generally relates to systems and methods for quantifying an analyte extracted from a sample. In certain embodiments, the invention provides methods that involve introducing a solvent into a capillary, introducing the capillary into a vessel including a sample such that a portion of the sample is introduced into the capillary, moving the sample and the solvent within the capillary to induce circulation within the sample and the solvent, thereby causing the analyte to be extracted from the sample and into the solvent, analyzing the analyte that has been extracted from the sample, and quantifying the analyte. In certain embodiments, the quantifying step is performed without knowledge of a volume of the sample and/or solvent. |
| FILED | Thursday, November 03, 2022 |
| APPL NO | 17/979972 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/167 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 436/24 (20150115) Y10T 436/255 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20230225315 | Steinmetz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicole F. Steinmetz (San Diego, California); Paul L. Chariou (Cleveland, Ohio) |
| ABSTRACT | A method of delivering an agricultural composition to a plant including determining a dose of the agricultural composition required to deliver a treatment effective amount of the at least one agrochemical agent to a target soil depth using a computational model, the agricultural composition including a plurality of plant viral nanoparticles (VNPs) and/or virus-like particles (VLPs) and at least one agrochemical agent, and applying the determined dose of the agricultural composition to the plant. |
| FILED | Monday, January 27, 2020 |
| APPL NO | 17/425909 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/28 (20130101) Original (OR) Class A01N 63/40 (20200101) Biocidal, Pest Repellant, Pest Attractant or Plant Growth Regulatory Activity of Chemical Compounds or Preparations A01P 5/00 (20210801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230225325 | ZHU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | New York University (New York, New York) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Xiaolong ZHU (New York, New York); Jingxiang YANG (New York, New York); Bart KAHR (Brooklyn, New York); Michael D. WARD (New York, New York) |
| ABSTRACT | The present invention relates to a novel crystalline form of deltamethrin, which is a pyrethroid compound useful as a pest control agent. The present invention further relates to a process of preparing the novel crystalline form, and to methods of controlling pests using the novel crystalline form. |
| FILED | Thursday, January 19, 2023 |
| APPL NO | 18/098925 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/12 (20130101) A01N 25/34 (20130101) A01N 53/00 (20130101) Original (OR) Class General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/13 (20130101) Acyclic or Carbocyclic Compounds C07C 255/41 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230225326 | Bowden et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| ASSIGNEE(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| INVENTOR(S) | Ned B. Bowden (Iowa City, Iowa); Justin M. CARTER (Iowa City, Iowa); Eric M. BROWN (Iowa City, Iowa); Nimesh RANASINGHE (Iowa City, Iowa); Arjun PAUDEL (Iowa City, Iowa); Erin E. IRISH (Iowa City, Iowa) |
| ABSTRACT | The invention provides a compound of formula I: wherein X, Y, Z, R′, R2, and X+ have any of the values described in the specification. The compounds are useful to increase plant growth and/or to increase harvest yield. |
| FILED | Tuesday, February 28, 2023 |
| APPL NO | 18/115700 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 57/12 (20130101) Original (OR) Class A01N 59/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230225328 | DUCKER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (Blacksburg, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | William DUCKER (Blacksburg, Virginia); Saeed BEHZADINASAB (Blacksburg, Virginia); Mohsen HOSSEINI (Blacksburg, Virginia); Gary WHITING (North East, Maryland) |
| ABSTRACT | In one aspect, the disclosure relates to antimicrobial films for use on high-touch surfaces in medical, commercial, and residential settings and methods of making the same. The films and coatings are robust and retain activity over time and are optimized to minimize diffusion time of virus particles as well as bacterial and fungal pathogens to the inactivating layers and/or particles in the films and coatings. In another aspect, the films and coatings are capable of inactivating multiple virus, bacteria, and fungi types, can be applied as sprayable coatings or adhesive backed films, or can be incorporated into fabrics. In still another aspect, the films and coatings can be formulated as transparent or can be a neutral color such as gray or white. |
| FILED | Thursday, May 27, 2021 |
| APPL NO | 17/928337 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/10 (20130101) A01N 25/34 (20130101) A01N 59/00 (20130101) A01N 59/06 (20130101) A01N 59/16 (20130101) A01N 59/20 (20130101) Original (OR) Class Biocidal, Pest Repellant, Pest Attractant or Plant Growth Regulatory Activity of Chemical Compounds or Preparations A01P 1/00 (20210801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230225357 | GIBBONS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PRAIRIE AQUATECH LLC (Brookings, South Dakota) |
| ASSIGNEE(S) | PRAIRIE AQUATECH LLC (Brookings, South Dakota) |
| INVENTOR(S) | WILLIAM GIBBONS (BROOKINGS, South Dakota); Michael L. Brown (Volga, South Dakota) |
| ABSTRACT | The present invention describes a bio-based process to produce high quality protein concentrate (HQPC) by converting plant derived celluloses into bioavailable protein via aerobic incubation, including the use of such HQPC so produced as a nutrient, including use as a fish meal replacement in aquaculture diets. |
| FILED | Friday, January 06, 2023 |
| APPL NO | 18/093884 |
| CURRENT CPC | Protein Compositions for Foodstuffs; Working-up Proteins for Foodstuffs; Phosphatide Compositions for Foodstuffs A23J 1/14 (20130101) A23J 1/125 (20130101) Original (OR) Class A23J 1/148 (20130101) Fodder A23K 10/14 (20160501) A23K 10/38 (20160501) A23K 20/147 (20160501) A23K 40/20 (20160501) A23K 40/25 (20160501) A23K 50/80 (20160501) Technologies for Adaptation to Climate Change Y02A 40/818 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230225358 | GIBBONS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PRAIRIE AQUATECH LLC (Brookings, South Dakota) |
| ASSIGNEE(S) | PRAIRIE AQUATECH LLC (Brookings, South Dakota) |
| INVENTOR(S) | WILLIAM GIBBONS (BROOKINGS, South Dakota); Michael L Brown (Volga, South Dakota) |
| ABSTRACT | The present invention describes a bio-based process to produce high quality protein concentrate (HQPC) by converting plant derived celluloses into bioavailable protein via aerobic incubation, including the use of such HQPC so produced as a nutrient, including use as a fish meal replacement in aquaculture diets. |
| FILED | Friday, January 06, 2023 |
| APPL NO | 18/093889 |
| CURRENT CPC | Protein Compositions for Foodstuffs; Working-up Proteins for Foodstuffs; Phosphatide Compositions for Foodstuffs A23J 1/14 (20130101) A23J 1/125 (20130101) Original (OR) Class A23J 1/148 (20130101) Fodder A23K 10/14 (20160501) A23K 10/38 (20160501) A23K 20/147 (20160501) A23K 40/20 (20160501) A23K 40/25 (20160501) A23K 50/80 (20160501) Technologies for Adaptation to Climate Change Y02A 40/818 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230225969 | CAO |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WAYNE STATE UNIVERSITY (Detroit, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhiqiang CAO (Troy, Michigan) |
| ABSTRACT | Compositions and methods for oral and/or mucosal administration of a biologically active agent are provided according to aspects of the present disclosure which include: a plurality of particles, wherein each particle has an exterior surface, the exterior surface defining a particle interior, the exterior surface having at least one type of zwitterionic polymer and/or zwitterionic copolymer disposed thereon and/or extending therefrom; and a biologically active agent disposed on the exterior surface and/or in the particle interior, wherein the biologically active agent is or includes a protein, peptide, or dietary supplement. According to particular aspects, compositions and methods for oral and/or mucosal administration of an anti diabetes biological agent, such as insulin and/or an insulin analog. |
| FILED | Thursday, May 20, 2021 |
| APPL NO | 17/925234 |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/155 (20160801) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 9/1075 (20130101) Original (OR) Class A61K 38/26 (20130101) A61K 38/28 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230225982 | MOON et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | JOONG HO MOON (WESTON, Florida); ALFONSO BARRIOS (MIAMI, Florida); MARIO DIAZ (MIAMI, Florida) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (MIAMI, Florida) |
| INVENTOR(S) | JOONG HO MOON (WESTON, Florida); ALFONSO BARRIOS (MIAMI, Florida); MARIO DIAZ (MIAMI, Florida) |
| ABSTRACT | The subject invention provides materials and methods for intracellular deliver of molecules and/or therapeutic agents. The subject invention also provides methods for synthesizing polymeric systems and nanomaterials that enhance or assist the passage of molecules and/or therapeutic agents across biological membranes. The compound, polymer or nanoparticle of the subject invention comprises a modified guanidine moiety in a plurality of repeating units of a polymer or on the surface of a nanoparticle where the guanidine moiety comprises, for example, a carbamoyl or thiourea modification. The polymer or nanoparticle can be used in a cancer treatment formulation. |
| FILED | Thursday, October 13, 2022 |
| APPL NO | 17/965330 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5115 (20130101) A61K 9/5138 (20130101) Original (OR) Class A61K 47/32 (20130101) A61K 47/34 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 43/00 (20180101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Heterocyclic Compounds C07D 491/048 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/125 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226504 | Masoudi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | EMISSOL, LLC (Mill Creek, Washington) |
| ASSIGNEE(S) | EMISSOL, LLC (MILL CREEK, Washington) |
| INVENTOR(S) | Mansour Masoudi (Mill Creek, Washington); Sahm Noorfeshan (Snohomish, Washington); Nikolai Alex Poliakov (Lynwood, Washington) |
| ABSTRACT | A segmented, heated urea mixer and an exhaust system to control NOx emission from combustion engines comprising a plurality of elements, at least one mixing element independently heatable by an external power source to a temperature above a temperature of another element. A method of using the exhaust gas mixer and an exhaust gas mixer system further comprising a controller is also disclosed. |
| FILED | Friday, December 09, 2022 |
| APPL NO | 18/078791 |
| CURRENT CPC | Separation B01D 53/9418 (20130101) B01D 53/9431 (20130101) Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 25/3141 (20220101) Original (OR) Class B01F 25/4314 (20220101) B01F 25/4317 (20220101) B01F 25/43197 (20220101) B01F 35/93 (20220101) B01F 2035/99 (20220101) Gas-flow Silencers or Exhaust Apparatus for Machines or Engines in General; Gas-flow Silencers or Exhaust Apparatus for Internal Combustion Engines F01N 3/2066 (20130101) F01N 3/2892 (20130101) F01N 2610/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227305 | Painter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Oskar Painter (Sierra Madre, California); Jie Luo (Pasadena, California); Michael T. Fang (Pasadena, California); Alp Sipahigil (Pasadena, California); Paul B. Dieterle (Somerville, Massachusetts); Mahmoud Kalaee (Pasadena, California); Johannes M. Fink (Klosterneuburg, Austria); Andrew J. Keller (Los Angeles, California); Gregory MacCabe (Los Angeles, California); Hengjiang Ren (Pasadena, California); Justin D. Cohen (Annandale, Virginia) |
| ABSTRACT | Embodiments described herein include systems and techniques for converting (i.e., transducing) a quantum-level (e.g., single photon) signal between the three wave forms (i.e., optical, acoustic, and microwave). A suspended crystalline structure is used at the nanometer scale to accomplish the desired behavior of the system as described in detail herein. Transducers that use a common acoustic intermediary transform optical signals to acoustic signals and vice versa as well as microwave signals to acoustic signals and vice versa. Other embodiments described herein include systems and techniques for storing a qubit in phonon memory having an extended coherence time. A suspended crystalline structure with specific geometric design is used at the nanometer scale to accomplish the desired behavior of the system. |
| FILED | Tuesday, March 21, 2023 |
| APPL NO | 18/187419 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/40 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227631 | Keith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MITO Material Solutions, Inc. (Indiana, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kevin Keith (Carmel, Indiana); Bhishma Sedai (Stillwater, Oklahoma) |
| ABSTRACT | A high-performance composite material is provided including a polymer and a hybrid nanoadditive dispersed throughout the polymer at a low concentration and without agglomeration. The hybrid nanoadditive includes a first, graphene oxide portion and a second, polyhedral oligomeric silesquioxane (POSS) portion. Associated extrusion systems and methods are also provided. |
| FILED | Tuesday, June 15, 2021 |
| APPL NO | 18/010379 |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/226 (20130101) C08J 2363/00 (20130101) C08J 2377/06 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/549 (20130101) Original (OR) Class C08K 2201/005 (20130101) C08K 2201/011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227693 | Fini et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Elham Fini (Phoenix, Arizona); Albert Hung (Tempe, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Elham Fini (Phoenix, Arizona); Albert Hung (Tempe, Arizona) |
| ABSTRACT | A coating composition includes alkaline mineral particles including an oxide of an alkaline earth metal and an amine-containing polymer. The amine-containing polymer is adsorbed on the alkaline mineral particles. Forming a coating composition includes at least partially coating alkaline mineral particles with an amine-containing polymer and dispersing the alkaline mineral particles in a liquid to yield the coating composition. The alkaline mineral particles include an oxide of an alkaline earth metal. |
| FILED | Thursday, January 19, 2023 |
| APPL NO | 18/156901 |
| CURRENT CPC | Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 7/20 (20180101) C09D 7/61 (20180101) C09D 7/65 (20180101) C09D 7/67 (20180101) C09D 177/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227837 | Koo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE CURATORS OF THE UNIVERSITY OF MISSOURI (Columbia, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeong-Kyu Abraham Koo (Columbia, Missouri); Athen N. Kimberlin (Columbia, Missouri) |
| ABSTRACT | The disclosure relates to compositions and methods for increasing oil content of the vegetative tissues of plants. The compositions comprise polynucleotides encoding phospholipase A1 (PLA1) polypeptides and plants, plant parts, plant cells, and seeds comprising such polynucleotides. The methods for increasing oil content of the vegetative tissues of plants comprise introducing a polynucleotide encoding PLA1 polypeptides into the plant. Expression of these PLA1 polynucleotides result in a large accumulation of triacyl glycerides or neutral lipids in vegetative tissues such as leaves that normally contain very little amount of such oil. |
| FILED | Thursday, August 18, 2022 |
| APPL NO | 17/820696 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/18 (20130101) C12N 15/8247 (20130101) Original (OR) Class Enzymes C12Y 301/01032 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227864 | Lynch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Michael David Lynch (Durham, North Carolina); Shuai Li (Durham, North Carolina) |
| ABSTRACT | The present disclosure is related to genetically engineered microbial strains and related bioprocesses for the production of products from acetyl-CoA. Specifically, the use of dynamically controlled synthetic metabolic valves to reduce the activity of certain enzymes, leads to increased product production in a two-stage process. |
| FILED | Friday, July 23, 2021 |
| APPL NO | 18/006506 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) C12N 9/0008 (20130101) C12N 9/0067 (20130101) C12N 9/1025 (20130101) C12N 15/11 (20130101) C12N 15/70 (20130101) C12N 15/635 (20130101) C12N 2310/20 (20170501) C12N 2800/101 (20130101) C12N 2830/001 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/44 (20130101) Original (OR) Class Enzymes C12Y 101/01049 (20130101) C12Y 102/04001 (20130101) C12Y 112/07002 (20130101) C12Y 203/03001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227891 | Seelig et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Georg Seelig (Seattle, Washington); Richard Muscat (London, United Kingdom); Alexander B. Rosenberg (Seattle, Washington) |
| ABSTRACT | Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens. |
| FILED | Tuesday, January 24, 2023 |
| APPL NO | 18/158487 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6855 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227944 | Manuel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida); UTBATTELLE, LLC (OAK RIDGE, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michele Viola Manuel (GAINESVILLE, Florida); HUNTER B. HENDERSON (GAINESVILLE, Florida); ORLANDO RIOS (OAK RIDGE, Tennessee); GERARD M. LUDTKA (OAK RIDGE, Tennessee) |
| ABSTRACT | Disclosed herein is a method comprising disposing a container containing a metal and/or ferromagnetic solid and abrasive particles in a static magnetic field; where the container is surrounded by an induction coil; activating the induction coil with an electrical current, to heat up the metallic or ferromagnetic solid to form a fluid; generating sonic energy to produce acoustic cavitation and abrasion between the abrasive particles and the container; and producing nanoparticles that comprise elements from the container, the metal and/or the ferromagnetic solid and the abrasive particles. Disclosed herein too is a composition comprising first metal or a first ceramic; and particles comprising carbides and/or nitrides dispersed therein. Disclosed herein too is a composition comprising nanoparticles comprising chromium carbide, iron carbide, nickel carbide, γ-Fe and magnesium nitride. |
| FILED | Thursday, February 23, 2023 |
| APPL NO | 18/173158 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/00 (20130101) B22F 1/07 (20220101) B22F 1/12 (20220101) B22F 1/054 (20220101) B22F 9/06 (20130101) B22F 2009/042 (20130101) Alloys C22C 1/1084 (20130101) Original (OR) Class Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 1/00 (20130101) C25D 15/00 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/047 (20130101) H01F 1/442 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 6/367 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230228446 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zachary Lee (Ithaca, New York); Ke Zhang (Ithaca, New York) |
| ABSTRACT | An apparatus in one embodiment comprises at least one processing device. The processing device comprises a processor coupled to a memory, and is configured to obtain information characterizing operation of a heat pump at a particular energy usage location, and to process the obtained information in a reinforcement learning agent to generate at least one control signal for controlling the heat pump, wherein the reinforcement learning agent is implemented at least in part utilizing behavioral cloning of a model predictive control process. In some embodiments, the behavioral cloning of the model predictive control process comprises a constraint-informed parameter grouping (CIPG) phase, a training data generation phase and a model training phase. The apparatus can be implemented, for example, at least in part in a cloud-based processing platform, and/or at least in part in one or more of a smart meter, a smart thermostat, a smart-home controller or other smart-home device. |
| FILED | Thursday, January 19, 2023 |
| APPL NO | 18/099037 |
| CURRENT CPC | Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 11/46 (20180101) F24F 11/58 (20180101) F24F 11/64 (20180101) Original (OR) Class Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/042 (20130101) G05B 2219/2614 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230228563 | Liang |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rongguang Liang (Tucson, Arizona) |
| ABSTRACT | Methods, devices and systems describe compact and simple deflectometry configurations that can measure complex shapes of freeform surfaces. One deflectometry system includes a first panel and a second panel positioned at an offset position from each other to provide illumination for an object. The second panel, positioned closer to the object, is operable as a substantially transparent panel, and as a pixelated panel to provide structured light patterns. The system also includes two or more cameras positioned on the second panel an is operable in a first mode where the first panel provides a first structured illumination and the second panel is configured as a substantially transparent panel that allows the first structured illumination from the first panel to transmit toward the object. The system is also operable in a second mode where the second panel is configured to provide a second structured illumination for illuminating the object. |
| FILED | Wednesday, June 16, 2021 |
| APPL NO | 18/002397 |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/25 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230228689 | HEMLER et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (PITTSBURGH, Pennsylvania) |
| INVENTOR(S) | SARAH L. HEMLER (Geneva, Switzerland); KURT E. BESCHORNER (PITTSBURGH, Pennsylvania) |
| ABSTRACT | A system for monitoring the tread of a shoe includes a frame member, a waveguide structured to support the shoe when an outer sole of shoe is in contact with a surface of the waveguide, a light source structured to provide light within an edge of the waveguide such that the light will be internally reflected within the waveguide, and an imaging device structured and configured to generate an image of the outer sole of the shoe when the outer sole of shoe is in contact with the waveguide and the light is being provided within the waveguide. The system also includes a controller structured and configured to: (i) receive image data based on the image of the outer sole; (ii) determine from the image data a largest worn region size for the shoe; and (iii) determine a slip risk for the shoe based on the largest worn region size. |
| FILED | Friday, December 02, 2022 |
| APPL NO | 18/061215 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/8851 (20130101) Original (OR) Class G01N 2021/8874 (20130101) Optical Elements, Systems, or Apparatus G02B 6/42 (20130101) Image Data Processing or Generation, in General G06T 7/0002 (20130101) G06T 7/62 (20170101) Pictorial Communication, e.g Television H04N 23/56 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230229112 | Zhao et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jianbo Zhao (Tucson, Arizona); Benjamin Chrysler (Tucson, Arizona); Raymond Kostuk (Tucson, Arizona); Jilian Nguyen (Tucson, Arizona) |
| ABSTRACT | Methods, devices and systems for improved fabrication and measurement of holographic elements are described. One example method includes directing a reference and an object beam toward a holographic material for formation of a diffraction grating in the holographic material, and blocking one of the reference or the object beams to prevent the beam from reaching the holographic material for at least a portion of time during which the diffraction grating is being formed. During the blockage of the beam, a power level of a diffracted beam associated with the reference or the object beam that is not being blocked is measured. Based on the measured power level, it is then determined whether a particular diffraction grating efficiency is reached. The described techniques enable real-time measurement of diffraction grating efficiency as the grating is being formed and enable improved fabrication of holographic elements hat must meet precise diffraction grating efficiency requirements. |
| FILED | Tuesday, May 04, 2021 |
| APPL NO | 17/997924 |
| CURRENT CPC | Holographic Processes or Apparatus G03H 1/0248 (20130101) G03H 1/0402 (20130101) G03H 1/0486 (20130101) Original (OR) Class G03H 2001/0439 (20130101) G03H 2240/53 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230229439 | Huang et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jane Huang (Granger, Indiana); Michael Vierhauser (Linz, Austria); Ankit Agrawal (South Bend, Indiana) |
| ABSTRACT | Systems and methods for maintaining the safety of a software-based system. One method includes automatically generating a first artifact tree for a hazard for a first version of the system and automatically transforming the first artifact tree into a first augmented tree using a set of heuristics. The method also includes automatically generating a second artifact tree for the hazard for a second version of the system and automatically transforming the second artifact tree for the hazard into a second augmented tree using the set of heuristics. The method further includes automatically comparing the first augmented tree and the second augmented tree to generate a delta view, and automatically generating, based on the delta view, at least one selected from a group consisting of a safety warning for the second version of the software-based system and an actionable recommendation to maintain safety of the second version of the software-based system. |
| FILED | Tuesday, February 28, 2023 |
| APPL NO | 18/115272 |
| CURRENT CPC | Electric Digital Data Processing G06F 8/71 (20130101) Original (OR) Class G06F 11/3684 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230229946 | O'Shaughnessy et al. |
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| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew O'Shaughnessy (Atlanta, Georgia); Gregory Canal (Atlanta, Georgia); Marissa Connor (Atlanta, Georgia); Mark Davenport (Atlanta, Georgia); Christopher John Rozell (Atlanta, Georgia) |
| ABSTRACT | Methods, non-transitory computer readable media, and causal explanation computing apparatus that assists with generating and providing causal explanation of artificial intelligence models includes obtaining a dataset as an input for an artificial intelligence model, wherein the obtained dataset is filtered to a disentangled low-dimensional representation. Next, a plurality of first factors from the disentangled low-dimensional representation of the obtained data that affect an output of the artificial intelligence model is identified. Further, a generative mapping from the disentangled low-dimensional representation between the identified plurality of first factors and the output of the artificial intelligence model, using causal reasoning is determined. An explanation data is generated using the determined generative mapping, wherein the generated explanation data provides a description of an operation leading to the output of the artificial intelligence model using the identified plurality of first factors. The generated explanation data is provided via a graphical user. |
| FILED | Thursday, June 24, 2021 |
| APPL NO | 18/011629 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 5/045 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230229983 | Ruddell et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of Northern Arizona University (Flagstaff, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Benjamin Lyle Ruddell (Flagstaff, Arizona); Richard Rushforth (Flagstaff, Arizona); Jon Miller (Tempe, Arizona); Rahul Salla (Tempe, Arizona); Erzhena Soktoeva (Tempe, Arizona); Ramesh Gorantla (Tempe, Arizona) |
| ABSTRACT | Systems and methods for producing geospatial images representing flows of commodities between geographic regions and their dependencies are disclosed. Raw economic and other data associating with discrete geographic locations are combined with data metadata from other sources, including transportation network data. Images may be generated at user-specified degrees of commodity category granularity and geographic granularity and may be contain information at significantly higher degree of geographic granularity than the original raw economic data. Quantities of flows are represented graphically by parameters such as widths of lines, paths, or other graphic elements. |
| FILED | Wednesday, March 08, 2023 |
| APPL NO | 18/119029 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0484 (20130101) G06F 16/13 (20190101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0631 (20130101) Original (OR) Class G06Q 30/0201 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/1097 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230230484 | Al Faruque et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mohammad Abdullah Al Faruque (Irvine, California); Shih-Yuan Yu (Irvine, California); Arnav Vaibhav Malawade (Irvine, California); Deepan Muthirayan (Irvine, California); Pramod P. Khargonekar (Irvine, California) |
| ABSTRACT | The present invention is directed to a Spatiotemporal scene-graph embedding methodology that models scene-graphs and resolves safety-focused tasks for autonomous vehicles. The present invention features a computing system comprising instructions for accepting the one or more images, extracting one or more objects from each image, computing an inverse-perspective mapping transformation of the image to generate a bird's-eye view (BEV) representation of each image, calculating relations between each object for each image, and generating a scene-graph for each image based on the aforementioned calculations. The system may further comprise instructions for calculating a confidence value for whether or not a collision will occur through the generation of a spatio-temporal graph embedding based on a spatial graph embedding and a temporal model. |
| FILED | Monday, January 16, 2023 |
| APPL NO | 18/154987 |
| CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 30/0956 (20130101) B60W 60/0015 (20200201) B60W 2420/42 (20130101) B60W 2552/00 (20200201) B60W 2554/402 (20200201) B60W 2554/4041 (20200201) Traffic Control Systems G08G 1/166 (20130101) Original (OR) Class G08G 1/167 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230230735 | Taheri et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mitra Lenore Taheri (Philadelphia, Pennsylvania); Katie Jo Sunday (Reinholds, Pennsylvania); Steven Richard Spurgeon (Narberth, Pennsylvania); Steven Joseph May (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | DREXEL UNIVERSITY (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Mitra Lenore Taheri (Philadelphia, Pennsylvania); Katie Jo Sunday (Reinholds, Pennsylvania); Steven Richard Spurgeon (Narberth, Pennsylvania); Steven Joseph May (Philadelphia, Pennsylvania) |
| ABSTRACT | A soft magnetic composite comprising an iron or iron alloy ferromagnetic material coated with an oxide material. An interface between the ferromagnetic material and the layer of oxide contains antiphase domain boundaries. Two processes for producing a soft magnetic composite are also provided. One process includes depositing an oxide layer onto an iron or iron alloy ferromagnetic material by molecular beam epitaxy at a partial oxygen pressure of from 1×10−5 Torr to 1×10−7 Torr to form a coated composite. The other process includes milling an iron or iron alloy ferromagnetic material powder and an oxide powder by high-energy milling to form a mixture; compacting the mixture and curing in an inert gas atmosphere at a temperature from 500° C. to 1200° C. to form a soft magnetic composite. |
| FILED | Tuesday, February 28, 2023 |
| APPL NO | 18/175572 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/05 (20220101) B22F 1/07 (20220101) B22F 1/16 (20220101) B22F 3/02 (20130101) B22F 3/24 (20130101) B22F 9/04 (20130101) B22F 2003/248 (20130101) B22F 2009/041 (20130101) B22F 2009/043 (20130101) B22F 2301/35 (20130101) B22F 2302/25 (20130101) B22F 2302/45 (20130101) B22F 2304/10 (20130101) B22F 2304/15 (20130101) B22F 2998/10 (20130101) B22F 2999/00 (20130101) Alloys C22C 33/02 (20130101) C22C 2202/02 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/26 (20130101) H01F 1/33 (20130101) Original (OR) Class H01F 41/0246 (20130101) Dynamo-electric Machines H02K 1/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230230851 | KHAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | ASIF KHAN (IRMO, South Carolina); MVS CHANDRASHEKHAR (COLUMBIA, South Carolina); MD DIDARUL ALAM (WEST COLUMBIA, South Carolina); MIKHAIL E. GAEVSKI (MOUNT SINAI, New York) |
| ABSTRACT | The present disclosure relates to use of 193-nm excimer laser-based lift-off (LLO) of Al0.26Ga0.74N/GaN High-electron mobility transistors (HEMTs) with thick (t>10 μm) AlN heat spreading buffer layers grown over sapphire substrates. The use of the thick AlN heat spreading layer resulted in thermal resistance (Rth) of 16 Kmm/W for as-fabricated devices on sapphire, which is lower than the value of ≈25-50 Kmm/W for standard HEMT structures on sapphire without the heat-spreaders. Soldering the LLO devices onto a copper heat sink led to a further reduction of Rth to 8 Kmm/W, a value comparable to published measurements on bulk SiC substrates. The reduction in Rth by LLO and bonding to copper led to significantly reduced self-heating and drain current droop. A drain current density as high as 0.9 A/mm was observed despite a marginal reduction of the carrier mobility (≈1800 to ≈1500 cm2/Vs). This is the highest drain current density and mobility reported to-date for LLO AlGaN/GaN HEMTs. |
| FILED | Monday, November 14, 2022 |
| APPL NO | 17/986579 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02079 (20130101) H01L 21/4882 (20130101) Original (OR) Class H01L 21/7813 (20130101) H01L 23/3736 (20130101) H01L 29/205 (20130101) H01L 29/2003 (20130101) H01L 29/7786 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20230231142 — FUNCTIONALIZED CROSS-LINKED POLYMER NETWORKS, METHODS OF MAKING SAME, AND USES THEREOF
| US 20230231142 | Archer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lynden A. Archer (Ithaca, New York); Sanjuna Stalin (Perungu, India) |
| ABSTRACT | In various examples, a functionalized cross-linked polymer network includes a plurality of cross-linked multifunctional trione triazine groups, a plurality of disulfide groups, a plurality of cross-linked multifunctional ether groups, a plurality of cross-linked multifunctional polyether groups, or a combination thereof, a plurality of crosslinking multifunctional polyether groups, and a plurality of dangling groups, where individual cross-linked multifunctional trione triazine groups and/or cross-linked multifunctional disulfide groups and/or cross-linked multifunctional ether groups and/or cross-linked multifunctional polyether groups and individual crosslinking multifunctional polyether groups are connected by one or more covalent bond(s) and individual dangling groups may be connected to the network by a covalent bond. At least a portion of or all of the dangling groups may be halogenated. A functionalized cross-linked polymer network may be made by polymerization (e.g., Thiol-ene reach on(s)) of one or more functionalized monomer(s) and one or more multifunctional monomer(s). |
| FILED | Tuesday, June 01, 2021 |
| APPL NO | 17/927784 |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 75/045 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 181/02 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/134 (20130101) H01M 4/628 (20130101) Original (OR) Class H01M 10/0525 (20130101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230231508 | Davy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Andluca Technologies Inc. (Princeton, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicholas C. Davy (Philadelphia, Pennsylvania); Jason U. Wallace (Rochester, New York); Douglas H. Axtell (Rochester, New York) |
| ABSTRACT | Illustrative embodiments of the invention generally relate to photovoltaics and solar energy harvesting devices and, particularly, to those that are transparent or semi-transparent, allowing sufficient visible light through them to allow visualization of objects through them, and more particularly, to those that supplement their primary near ultraviolet light absorption with secondary and/or tertiary absorptions of narrow bands of visible light while maintaining their transparency. Various embodiments of the invention relate to single solar materials with both primary ultraviolet absorption and secondary, narrow-band visible absorption, while some embodiments of the invention utilize mixtures of one or more materials to realize a primary ultraviolet absorption of light with secondary, or even tertiary, narrow bands of visible light absorption. Means of manufacturing such photovoltaics and solar energy harvesting devices will also be disclosed as well as the applications and uses thereof. |
| FILED | Monday, March 20, 2023 |
| APPL NO | 18/123817 |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/157 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 20/22 (20141201) Original (OR) Class H02S 40/22 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230231575 | Kliewer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | New Jersey Institute of Technology (Newark, New Jersey) |
| ASSIGNEE(S) | New Jersey Institute of Technology (Newark, New Jersey) |
| INVENTOR(S) | Joerg Kliewer (Fair Lawn, New Jersey); Allison Beemer (Eau Claire, Wisconsin); Salman Habib (Newark, New Jersey) |
| ABSTRACT | Embodiments of the present disclosure relate to sequential decoding of moderate length low-density parity-check (LDPC) codes via reinforcement learning (RL). The sequential decoding scheme is modeled as a Markov decision process (MDP), and an optimized cluster scheduling policy is subsequently obtained via RL. A software agent is trained to schedule all check nodes (CNs) in a cluster, and all clusters in every iteration. A new RL state space model is provided that enables the RL-based decoder to be suitable for longer LDPC codes. |
| FILED | Tuesday, September 27, 2022 |
| APPL NO | 17/954120 |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 13/1125 (20130101) H03M 13/1128 (20130101) H03M 13/1131 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230232123 | O'Toole et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew O'Toole (Pittsburgh, Pennsylvania); Mark Sheinin (Pittsburgh, Pennsylvania); Srinivasa Narasimhan (Pittsburgh, Pennsylvania) |
| ABSTRACT | A novel class of imaging systems that combines diffractive optics with 1D line sensing is disclosed. When light passes through a diffraction grating or prism, it disperses as a function of wavelength. This property is exploited to recover 2D and 3D positions from line images. A detailed image formation model and a learning-based algorithm for 2D position estimation are disclosed. The disclosure includes several extensions of the imaging system to improve the accuracy of the 2D position estimates and to expand the effective field-of-view. The invention is useful for fast passive imaging of sparse light sources, such as streetlamps, headlights at night and LED-based motion capture, and structured light 3D scanning with line illumination and line sensing. |
| FILED | Friday, May 28, 2021 |
| APPL NO | 17/925064 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/70 (20170101) G06T 7/90 (20170101) G06T 2207/10024 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30204 (20130101) Pictorial Communication, e.g Television H04N 23/56 (20230101) H04N 23/95 (20230101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20230226462 | SABOE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Patrick Owen SABOE (Golden, Colorado); Ryan Lane PRESTANGEN (Golden, Colorado); Eric M. KARP (Denver, Colorado); Bryan PIVOVAR (Arvada, Colorado) |
| ABSTRACT | Embodiments of the hybrid thermal-chromatograph systems described herein solve the co-product generation problem associated with seawater desalination, and result in significant reduction in the selling price of fresh water generated through the process, while also solving problems associated with traditional lithium mining practices. |
| FILED | Wednesday, December 09, 2020 |
| APPL NO | 17/783716 |
| CURRENT CPC | Separation B01D 15/364 (20130101) B01D 15/1821 (20130101) Original (OR) Class Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/42 (20130101) C02F 2103/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226486 | Ding et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho); Kansas State University Research Foundation (Manhattan, Kansas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dong Ding (Idaho Falls, Idaho); Wei Wu (Idaho Falls, Idaho); Chuancheng Duan (Manhattan, Kansas) |
| ABSTRACT | A method for capturing carbon dioxide comprises introducing a first feed stream comprising carbon dioxide and dioxygen into a first electrochemical cell, reducing the carbon dioxide to carbonate ions at a first cathode of the first electrochemical cell, and reducing the carbonate ions at a first anode to produce a first product stream comprising concentrated carbon dioxide and a second product stream comprising water. A second feed stream comprising water is introduced to a second electrochemical cell coupled to the first electrochemical cell. The water is oxidized at a second anode of the second electrochemical cell to produce hydrogen ions and dioxygen gas, the hydrogen ions are reduced to hydrogen gas at a second cathode, and the hydrogen gas produced by the second cathode is transported to the first anode. The first product stream is removed from the first electrochemical cell. Additional methods and related systems are also disclosed. |
| FILED | Thursday, January 19, 2023 |
| APPL NO | 18/156626 |
| CURRENT CPC | Separation B01D 53/326 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/145 (20130101) H01M 8/0656 (20130101) H01M 8/04007 (20130101) H01M 2008/147 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226513 | Zheng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard F. Zheng (Lake Oswego, Oregon); Robert S. Wegeng (Richland, Washington); Paul H. Humble (Kennewick, Washington); Dustin D. Caldwell (Portland, Connecticut); Richard B. Diver (Albuquerque, New Mexico); Ward E. TeGrotenhuis (Kennewick, Washington); Christopher K. Clayton (Kennewick, Washington); Timothy G. Veldman (Kennewick, Washington) |
| ABSTRACT | Reactors are provided that can include a first set of fluid channels and a second set of fluid channels oriented in thermal contact with the first set of fluid channels. The reactor assemblies can also provide where the channels of either one or both of the first of the set of fluid channels are non-linear. Other implementations provide for at least one of the first set of fluid channels being in thermal contact with a plurality of other channels of the second set of fluid channels. Reactor assemblies are also provided that can include a first set of fluid channels defining at least one non-linear channel having a positive function, and a second set of fluid channels defining at least another non-linear channel having a negative function in relation to the positive function of the one non-linear channel of the first set of fluid channels. Processes for distributing energy across a reactor are provided. The processes can include transporting reactants via a first set of fluid channels to a second set of fluid channels, and thermally engaging at least one of the first set of fluid channels with at least two of the second set of fluid channels. |
| FILED | Monday, March 06, 2023 |
| APPL NO | 18/179358 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0013 (20130101) B01J 19/0093 (20130101) Original (OR) Class B01J 2219/00081 (20130101) B01J 2219/00788 (20130101) B01J 2219/00804 (20130101) B01J 2219/00873 (20130101) B01J 2219/00995 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/16 (20130101) C01B 3/38 (20130101) C01B 2203/063 (20130101) C01B 2203/066 (20130101) C01B 2203/0233 (20130101) C01B 2203/0283 (20130101) C01B 2203/0833 (20130101) C01B 2203/1241 (20130101) Solar Heat Collectors; Solar Heat Systems F24S 20/20 (20180501) F24S 90/00 (20180501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226527 | Chou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); UNM Rainforest Innovations (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stanley Shihyao Chou (Albuquerque, New Mexico); Christopher Ryan Riley (Albuquerque, New Mexico); Abhaya Datye (Albuquerque, New Mexico); Andrew de la Riva (Albuquerque, New Mexico) |
| ABSTRACT | High surface area, high entropy oxides comprising multiple metal cations in a single-phase fluorite lattice material enables intrinsic catalytic activity without platinum group metals, tunable oxygen storage capacity, and thermal stability. These properties can be obtained through a facile sol-gel synthesis to provide a low-temperature route for production of phase-pure multi-cationic oxides. The resulting materials achieved significantly higher surface area and catalytic performance, taking advantage of all the properties endowed by the various cations in the composition. |
| FILED | Thursday, February 09, 2023 |
| APPL NO | 18/107546 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/10 (20130101) B01J 23/34 (20130101) B01J 23/83 (20130101) Original (OR) Class B01J 35/1009 (20130101) B01J 37/04 (20130101) B01J 37/0018 (20130101) B01J 37/036 (20130101) B01J 37/088 (20130101) B01J 37/0236 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/50 (20170801) Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 17/241 (20200101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 45/1228 (20130101) C01G 49/0054 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/30 (20130101) C01P 2002/50 (20130101) C01P 2006/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226587 | LOJEK, III et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania) |
| ASSIGNEE(S) | Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania) |
| INVENTOR(S) | John LOJEK, III (Valencia, Pennsylvania); Matthew M SWARTZ (Claridge, Pennsylvania); William A. BYERS (Murrysville, Pennsylvania); Gregory A. KUSTRA (Gibsonia, Pennsylvania); David M. GROSS (Gibsonia, Pennsylvania) |
| ABSTRACT | A forming assembly for forming a wick is disclosed. The forming assembly includes a tube inflatable to an inflated configuration. A wick mesh is configured to be wrapped about the tube. The forming assembly further includes a sheath positionable about the tube and the wick mesh. The tube and the sheath are configured to compress the wick mesh and form the wick based on the tube inflating towards the inflated configuration. |
| FILED | Monday, April 19, 2021 |
| APPL NO | 17/996716 |
| CURRENT CPC | Working or Processing of Sheet Metal or Metal Tubes, Rods or Profiles Without Essentially Removing Material; Punching Metal B21D 26/033 (20130101) Original (OR) Class B21D 53/06 (20130101) Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 15/26 (20130101) B23P 2700/09 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226763 | Ring et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | FERMI RESEARCH ALLIANCE, LLC (Batavia, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Timothy Ring (Batavia, Illinois); Derek Plant (Batavia, Illinois) |
| ABSTRACT | Many materials (e.g., PVDF) are difficult to use in additive manufacturing processes because the material does not bond to the build platform of additive manufacturing machines. In order to use such materials, a build platform can use a difference in air pressure to hold a base film in position on a top plate of the build platform. An object is to be printed using the material and the base film is of a material that the material will bond to during the printing process. The difference in air pressure may be achieved using a build plate with a voided internal region and a top plate with apertures. A low pressure source can draw a vacuum in the voided internal region. Placing the base film over the apertures causes the base film to be held in place by the difference in air pressure. |
| FILED | Tuesday, January 17, 2023 |
| APPL NO | 18/098022 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/30 (20170801) B29C 64/245 (20170801) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226788 | Tobin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James Robert Tobin (Greenville, South Carolina); Paul Trevor Hayden (Romsey, United Kingdom); Harald Behmer (Newport, United Kingdom); Raphael Sajous (Cowes, United Kingdom); Hongyi Zhou (Schenectady, New York) |
| ABSTRACT | In an aspect, the present disclosure is directed to a composite structure. The composite structure includes a three-dimensional (3-D) grid structure and at least one monolithic skin layer at least partially enveloping and securing the grid structure. As such, the grid structure is configured to stabilize the composite structure under at least one of: static local buckling and dynamic global buckling. |
| FILED | Thursday, June 24, 2021 |
| APPL NO | 18/011217 |
| CURRENT CPC | Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 99/0014 (20130101) B29D 99/0028 (20130101) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227380 | LARSEN, III et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BATTELLE SAVANNAH RIVER ALLIANCE, LLC (AIKEN, South Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | GEORGE K. LARSEN, III (AIKEN, South Carolina); TYLER C. GUIN (AIKEN, South Carolina); JOSEPH E. MEANY (ATLANTA, Georgia); JAY B. GAILLARD (AIKEN, South Carolina); MARK C. ELVINGTON (AIKEN, South Carolina) |
| ABSTRACT | Disclosed are methods and systems for hydrogen isotope exchange of organic molecules that can be carried out with no alteration in the chemical structure of the organic molecules. Methods can be utilized to incorporate a particular hydrogen isotope on an organic molecule (e.g., deuteration or tritiation) or to remove a particular hydrogen isotope from an organic molecule (e.g., detritiation). |
| FILED | Friday, January 20, 2023 |
| APPL NO | 18/099455 |
| CURRENT CPC | Separation B01D 59/00 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 10/007 (20130101) B01J 19/24 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 59/001 (20130101) Original (OR) Class C07B 2200/05 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227602 | Foster et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeffrey Clayton Foster (Albuquerque, New Mexico); Erica Marie Redline (Albuquerque, New Mexico); Koushik Ghosh (Albuquerque, New Mexico); Chad Staiger (Albuquerque, New Mexico) |
| ABSTRACT | A method to synthesize a low thermal expansion thermoset comprises mixing a thermosetting resin and a benzocyclobutene curative having a reactive secondary functionalization; heating the mixture to a first temperature to from a pre-polymer comprising benzocyclobutene end groups and a thermoset linking group; and heating the pre-polymer to a second temperature sufficient for ring-opening of benzocyclobutene to occur, thereby forming a thermoset polymer network crosslinked with dibenzocyclooctene moieties. |
| FILED | Wednesday, January 18, 2023 |
| APPL NO | 18/098168 |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 59/4007 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227646 | Jones et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brad Howard Jones (Albuquerque, New Mexico); Samuel Leguizamon (Albuquerque, New Mexico) |
| ABSTRACT | Polymerization-induced phase separation enables fine control over thermoset network morphologies, yielding heterogeneous structures with domain sizes tunable over 1-100 nm. However, the controlled chain-growth polymerization techniques exclusively employed to regulate morphology at these length scales are unsuitable for most thermoset materials typically formed through step-growth mechanisms. By employing binary mixtures in place of the classic constituents of phase-separating thermosets—resin, curing agent, and secondary polymer—facile tunability over morphology can be achieved through a single compositional parameter. Indeed, this method yields morphologies spanning nano-scale to macro-scale, controlled by the relative reactivities and thermodynamic compatibility of the network components. Due to the connection between chain dynamics and microstructure in these materials, the tunable morphology enables exquisite control over glass transition and other physical and mechanical properties. |
| FILED | Monday, January 17, 2022 |
| APPL NO | 17/577111 |
| CURRENT CPC | Compositions of Macromolecular Compounds C08L 63/00 (20130101) Original (OR) Class C08L 2205/035 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227677 | Fenn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David R. Fenn (Allison Park, Pennsylvania); Kurt G. Olson (Gibsonia, Pennsylvania); Reza M. Rock (Pittsburgh, Pennsylvania); Cynthia Kutchko (Pittsburgh, Pennsylvania); Susan F. Donaldson (Allison Park, Pennsylvania); Hao Sun (Allison Park, Pennsylvania) |
| ABSTRACT | Methods of printing a three-dimensional object using co-reactive components are disclosed. Thermosetting compositions for three-dimensional printing are also disclosed. |
| FILED | Wednesday, March 15, 2023 |
| APPL NO | 18/184138 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/112 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2075/02 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/10 (20130101) C08G 18/73 (20130101) C08G 18/325 (20130101) C08G 18/755 (20130101) C08G 18/792 (20130101) C08G 18/3225 (20130101) C08G 18/3228 (20130101) C08G 18/3234 (20130101) C08G 18/3821 (20130101) C08G 18/4854 (20130101) C08G 18/5024 (20130101) C08G 18/7893 (20130101) C08G 2150/50 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/36 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/03 (20130101) C09D 11/30 (20130101) C09D 11/38 (20130101) C09D 11/102 (20130101) Original (OR) Class C09D 175/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227721 | Fan |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hongyou Fan (Albuquerque, New Mexico) |
| ABSTRACT | A bi-phased approach between good solvents (or non-polar) and bad solvents (polar) can be used to assemble nanorods into highly ordered monolayers or multilayers of ordered nanorod arrays. These ordered nanorod arrays can display unique optical properties. For example, ordered arrays of CdSe/CdS core/shell nanorods were assembled that display polarized photoluminescence. |
| FILED | Wednesday, January 19, 2022 |
| APPL NO | 17/579239 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 49/08 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/025 (20130101) C09K 11/883 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227810 | Gill et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Inscripta, Inc. (Boulder, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ryan T. Gill (Denver, Colorado); Andrew Garst (Boulder, Colorado); Tanya Elizabeth Warnecke Lipscomb (Boulder, Colorado); Marcelo Colika Bassalo (Boulder, Colorado); Ramsey Ibrahim Zeitoun (San Francisco, California) |
| ABSTRACT | Provided herein are methods and composition for trackable genetic variant libraries. Further provided herein are methods and compositions for recursive engineering. Further provided herein are methods and compositions for multiplex engineering. Further provided herein are methods and compositions for enriching for editing and trackable engineered sequences and cells using nucleic acid-guided nucleases. |
| FILED | Friday, January 20, 2023 |
| APPL NO | 18/157740 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 15/102 (20130101) C12N 15/1065 (20130101) Original (OR) Class C12N 15/1079 (20130101) C12N 15/1082 (20130101) C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227861 | Hittinger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chris Todd Hittinger (Madison, Wisconsin); Trey Sato (Madison, Wisconsin); Sae-Byuk Lee (Madison, Wisconsin) |
| ABSTRACT | An engineered yeast strain capable of efficient fermentation of xylose to ethanol, and methods of making and using the strain, are provided |
| FILED | Thursday, November 03, 2022 |
| APPL NO | 18/052410 |
| CURRENT CPC | Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/02 (20130101) C10L 2200/0469 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/92 (20130101) C12N 9/0093 (20130101) C12N 9/1022 (20130101) C12N 9/1205 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/10 (20130101) Original (OR) Class Enzymes C12Y 117/99 (20130101) C12Y 202/01002 (20130101) C12Y 207/01017 (20130101) C12Y 503/01005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227864 | Lynch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Michael David Lynch (Durham, North Carolina); Shuai Li (Durham, North Carolina) |
| ABSTRACT | The present disclosure is related to genetically engineered microbial strains and related bioprocesses for the production of products from acetyl-CoA. Specifically, the use of dynamically controlled synthetic metabolic valves to reduce the activity of certain enzymes, leads to increased product production in a two-stage process. |
| FILED | Friday, July 23, 2021 |
| APPL NO | 18/006506 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) C12N 9/0008 (20130101) C12N 9/0067 (20130101) C12N 9/1025 (20130101) C12N 15/11 (20130101) C12N 15/70 (20130101) C12N 15/635 (20130101) C12N 2310/20 (20170501) C12N 2800/101 (20130101) C12N 2830/001 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/44 (20130101) Original (OR) Class Enzymes C12Y 101/01049 (20130101) C12Y 102/04001 (20130101) C12Y 112/07002 (20130101) C12Y 203/03001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227895 | Church et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | George M. Church (Brookline, Massachusetts); Je-Hyuk Lee (Allston, Massachusetts); Evan R. Daugharthy (Cambridge, Massachusetts) |
| ABSTRACT | Methods of labelling one or more subcellular components (e.g., an organelle and/or subcellular region) in vivo are provided. Methods of labelling a protein in vivo are provided. Methods of determining a nucleic acid sequence in situ are also provided. |
| FILED | Friday, January 20, 2023 |
| APPL NO | 18/157108 |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) C07H 21/04 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6841 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227943 | Taleyarkhan |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Rusi P. Taleyarkhan (Lafayette, Indiana) |
| ABSTRACT | The method of separating an actinide within a mixture of an Rn-progeny alpha emitting isotope includes disposing a continuous air monitoring filter in acetone. The acetone is then evaporated, thereby forming a residue. The residue is mixed with a first solution including nitric acid, thus forming a first blend. The first blend is mixed with a second solution including an extraction solvent, thus forming a second blend. The second blend is stratified into a first layer and a second layer. The first layer is extracted from the second blend, thus separating the actinide from the Rn-progeny alpha emitting isotope. |
| FILED | Friday, January 20, 2023 |
| APPL NO | 18/099307 |
| CURRENT CPC | Production and Refining of Metals; Pretreatment of Raw Materials C22B 7/006 (20130101) C22B 60/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227944 | Manuel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida); UTBATTELLE, LLC (OAK RIDGE, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michele Viola Manuel (GAINESVILLE, Florida); HUNTER B. HENDERSON (GAINESVILLE, Florida); ORLANDO RIOS (OAK RIDGE, Tennessee); GERARD M. LUDTKA (OAK RIDGE, Tennessee) |
| ABSTRACT | Disclosed herein is a method comprising disposing a container containing a metal and/or ferromagnetic solid and abrasive particles in a static magnetic field; where the container is surrounded by an induction coil; activating the induction coil with an electrical current, to heat up the metallic or ferromagnetic solid to form a fluid; generating sonic energy to produce acoustic cavitation and abrasion between the abrasive particles and the container; and producing nanoparticles that comprise elements from the container, the metal and/or the ferromagnetic solid and the abrasive particles. Disclosed herein too is a composition comprising first metal or a first ceramic; and particles comprising carbides and/or nitrides dispersed therein. Disclosed herein too is a composition comprising nanoparticles comprising chromium carbide, iron carbide, nickel carbide, γ-Fe and magnesium nitride. |
| FILED | Thursday, February 23, 2023 |
| APPL NO | 18/173158 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/00 (20130101) B22F 1/07 (20220101) B22F 1/12 (20220101) B22F 1/054 (20220101) B22F 9/06 (20130101) B22F 2009/042 (20130101) Alloys C22C 1/1084 (20130101) Original (OR) Class Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 1/00 (20130101) C25D 15/00 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/047 (20130101) H01F 1/442 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 6/367 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227988 | Balema et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Viktor Balema (Ames, Iowa); Sonal Padalkar (Ames, Iowa); Ihor Hlova (Ames, Iowa); Tian Lan (Fremont, California); Oleksandr Dolotko (Kartsruhe, Germany); Vitalij K. Pecharsky (Ames, Iowa); Duane D. Johnson (Ames, Iowa); Arjun K. Pathak (East Amherst, New York); Prashant Singh (Ames, Iowa) |
| ABSTRACT | A cathode is provided for electrolysis of water wherein the cathode material comprises a multi-principal element, transition metal dichalcogenide material that has four or more chemical elements and that is a single phase, solid solution. The pristine cathode material does not contain platinum as a principal (major) component. However, a cathode comprising a transition metal dichalcogenide having platinum (Pt) nanosized islands or precipitates disposed thereon is also provided. |
| FILED | Thursday, January 12, 2023 |
| APPL NO | 17/803894 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 18/42 (20130101) C23C 18/1639 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 11/051 (20210101) C25B 11/057 (20210101) C25B 11/075 (20210101) Original (OR) Class C25B 11/091 (20210101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 3/50 (20130101) C25D 5/02 (20130101) C25D 13/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230228800 | Owens et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Israel Owens (Albuquerque, New Mexico); Andrew Charles Biller (Albuquerque, New Mexico) |
| ABSTRACT | The present invention is directed to an electro-optical sensor for high intensity electric field measurement. The electro-optical sensor was used to measure a strong 118 MV/m narrow pulse width (˜33 ns) electric field in the magnetically insulated transmission line (MITL) of a pulsed power accelerator. Accurately measuring these high fields using conventional pulsed power diagnostics is difficult due to the strength of interfering particles and fields. The electro-optical sensor uses a free space laser beam with a dielectric crystal sensor that is highly immune to electromagnetic interference and does not require an external calibration. |
| FILED | Tuesday, January 10, 2023 |
| APPL NO | 18/095153 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 29/0885 (20130101) Original (OR) Class Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0136 (20130101) G02F 1/0311 (20130101) G02F 2201/58 (20130101) G02F 2202/20 (20130101) G02F 2202/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230229494 | HASSAAN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ADVANCED MICRO DEVICES, INC. (Santa Clara, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Muhammad Amber HASSAAN (Austin, Texas); Anirudh Mohan KAUSHIK (Austin, Texas); Sooraj PUTHOOR (Austin, Texas); Gokul Subramanian RAVI (Austin, Texas); Bradford BECKMANN (Bellevue, Washington); Ashwin AJI (Santa Clara, California) |
| ABSTRACT | A processor includes a task scheduling unit and a compute unit coupled to the task scheduling unit. The task scheduling unit performs a task dependency assessment of a task dependency graph and task data requirements that correspond to each task of the plurality of tasks. Based on the task dependency assessment, the task scheduling unit schedules a first task of the plurality of tasks and a second proxy object of a plurality of proxy objects specified by the task data requirements such that a memory transfer of the second proxy object of the plurality of proxy objects occurs while the first task is being executed. |
| FILED | Wednesday, January 11, 2023 |
| APPL NO | 18/095704 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/52 (20130101) G06F 9/4881 (20130101) Original (OR) Class G06F 16/9024 (20190101) G06F 2209/486 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230229784 | CHOI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (Gwangju, South Korea); OFFICE OF SCIENCE and TECHNOLOGY, VIETNAM NATIONAL UNIVERSITY HO CHI MINH CITY - UNIVERSITY OF SCIENCE (Ho Chi Minh, Viet Nam) |
| ASSIGNEE(S) | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (Gwangju, South Korea); OFFICE OF SCIENCE and TECHNOLOGY, VIETNAM NATIONAL UNIVERSITY HO CHI MINH CITY - UNIVERSITY OF SCIENCE (Ho Chi Minh, Viet Nam) |
| INVENTOR(S) | Deokjai CHOI (Gwangju, South Korea); Mai Thao DANG (Gwangju, South Korea); Dinh Thuc NGUYEN (Ho Chi Minh, Viet Nam) |
| ABSTRACT | A personal information security system and a method thereof ensuring irreversibility and similarity are proposed. According to specific exemplary embodiments of the present technology, the personal information security system includes a feature vector extraction unit for extracting a feature vector from user modality information, an Absolute Value Equations Transform (AVET) unit for performing absolute value equations transform on the feature vector, and a transformed-template generation unit for generating a transformed template (TT) from which the feature vector is unable to be predicted reversely from a result of the AVET. |
| FILED | Wednesday, January 04, 2023 |
| APPL NO | 18/093321 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/577 (20130101) Original (OR) Class G06F 21/602 (20130101) G06F 21/6245 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230229995 | Papalexopoulos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Zome Energy Networks, Inc. (San Francisco, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alex Papalexopoulos (San Francisco, California); Shmuel Oren (Berkeley, California) |
| ABSTRACT | A virtual power plant manages power consumption of various assets and curtails the power consumption of the assets based, at least in part, on power consumption flexibility of the assets. Curtailing the power consumption of the assets reduces electricity required which is effectively the same as generating electricity. The electricity that has been reduced by the curtailment may be subsequently resold on the wholesale market. |
| FILED | Tuesday, January 17, 2023 |
| APPL NO | 18/155522 |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/06312 (20130101) Original (OR) Class G06Q 50/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230230762 | Hesterman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Bryce Leonard Hesterman (Providence, Utah); Dorai Babu Yelaverthi (Raleigh, North Carolina) |
| ASSIGNEE(S) | Utah State University (Logan, Utah) |
| INVENTOR(S) | Bryce Leonard Hesterman (Providence, Utah); Dorai Babu Yelaverthi (Raleigh, North Carolina) |
| ABSTRACT | An apparatus for a transformer with an insulating divider includes a primary winding proximate to a primary magnetic core assembly and a secondary winding proximate to a secondary magnetic core assembly. The primary magnetic core assembly and the secondary magnetic core assembly are made of materials with a high magnetic permeability. The apparatus includes a divider placed between the primary and secondary magnetic core assemblies. The divider includes an electrically insulating material. The apparatus includes an electrically insulating potting material surrounding each of the magnetic core assemblies in a vicinity of the divider. |
| FILED | Friday, January 13, 2023 |
| APPL NO | 18/097183 |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 27/263 (20130101) H01F 27/306 (20130101) H01F 27/324 (20130101) Original (OR) Class H01F 2038/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230230776 | Penner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Reginald M. Penner (Newport Beach, California); Mya Le Thai (Irvine, California) |
| ABSTRACT | A nanowire energy storage device such as a nanowire battery or a capacitor having a cathode comprising a plurality of nanowires and an anode comprising a plurality of nanowires interlaced with the plurality of nanowires of the cathode, and embedded in a PMMA gel electrolyte. |
| FILED | Wednesday, December 07, 2022 |
| APPL NO | 18/077052 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/24 (20130101) H01G 11/36 (20130101) Original (OR) Class H01G 11/46 (20130101) H01G 11/56 (20130101) H01G 11/80 (20130101) H01G 11/86 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/661 (20130101) H01M 10/0565 (20130101) H01M 12/02 (20130101) H01M 2010/0495 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230231200 | LIU et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gao LIU (Piedmont, California); Thanh-Nhan TRAN (Berkeley, California) |
| ABSTRACT | The present invention provides for an electrolyte composition comprising an ether solvent, an amphiphilic molecule, an electrolyte solvent, and a lithium salt. |
| FILED | Friday, December 09, 2022 |
| APPL NO | 18/064187 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0567 (20130101) H01M 10/0569 (20130101) Original (OR) Class H01M 2300/0034 (20130101) H01M 2300/0037 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230231392 | Xue |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lingxiao Xue (Oak Ridge, Tennessee) |
| ABSTRACT | A power sharing multiport charger or a power sharing multiport supply is provided. The power sharing may be provided via time division multiplexing of power output from a switch mode power supply. |
| FILED | Wednesday, January 11, 2023 |
| APPL NO | 18/095765 |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0019 (20130101) Original (OR) Class H02J 7/0024 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230231489 | Xue |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lingxiao Xue (Oak Ridge, Tennessee) |
| ABSTRACT | A rectifier for use in a power supply is provided, including a capacitor charge control circuit operable to enable reduction in bulk capacitance. |
| FILED | Wednesday, January 11, 2023 |
| APPL NO | 18/095780 |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 7/1555 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230231746 | Deptuch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brookhaven Science Associates, LLC (Upton, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Grzegorz W. Deptuch (Great Neck, New York); Nicholas Benjamin St. John (East Patchogue, New York); Soumyajit Mandal (Merrick, New York) |
| ABSTRACT | An adaptive line driver circuit configured to transmit a signal over a wired link includes a delay-locked loop (DLL) circuit, which includes a phase detector (PD) circuit, charge pump (CP) circuit, and voltage-controlled delay line (VCDL) circuit operatively coupled together. The delay-locked loop circuit provides pre-emphasis and feed-forward equalization of the signal. The delay locked loop circuit also provides a user-configurable parameter including at least one of pre-data tap amplitude, data tap amplitude, post-data tap amplitude, pre-data tap duration, post-data tap duration, pre-data tap quantity, and post-data tap quantity. The adaptive line driver circuit further includes a source-series terminated (SST) driver circuit operatively coupled to the delay-locked loop circuit. |
| FILED | Friday, January 06, 2023 |
| APPL NO | 18/151171 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 7/0331 (20130101) H04L 25/03038 (20130101) Original (OR) Class H04L 2025/03477 (20130101) H04L 2025/03509 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20230226190 | HAGGARD et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Memphis Research Foundation (Memphis, Tennessee) |
| ASSIGNEE(S) | The University of Memphis Research Foundation (Memphis, Tennessee) |
| INVENTOR(S) | Warren O. HAGGARD (Memphis, Tennessee); Scott P. NOEL (Memphis, Tennessee); Joel D. BUMGARDNER (Memphis, Tennessee) |
| ABSTRACT | The invention provides compositions featuring chitosan and methods for using such compositions for the local delivery of biologically active agents to an open fracture, complex wound or other site of infection. Advantageously, the degradation and drug elution profiles of the chitosan compositions can be tailored to the needs of particular patients at the point of care (e.g., in a surgical suite, clinic, physician's office, or other clinical setting). |
| FILED | Friday, January 27, 2023 |
| APPL NO | 18/102123 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 9/7007 (20130101) A61K 31/00 (20130101) A61K 31/7036 (20130101) A61K 38/14 (20130101) A61K 47/36 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/28 (20130101) A61L 15/44 (20130101) A61L 27/20 (20130101) A61L 27/58 (20130101) A61L 29/16 (20130101) A61L 29/043 (20130101) A61L 29/146 (20130101) A61L 29/148 (20130101) A61L 31/16 (20130101) A61L 31/042 (20130101) A61L 31/146 (20130101) A61L 31/148 (20130101) A61L 2300/25 (20130101) A61L 2300/232 (20130101) A61L 2300/406 (20130101) Polysaccharides; Derivatives Thereof C08B 37/003 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/18 (20130101) C08J 2305/08 (20130101) Compositions of Macromolecular Compounds C08L 5/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226535 | ZHOU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chen ZHOU (Chandler, Arizona); Bruce RITTMAN (Tempe, Arizona); Dandan ZHOU (Changchun, China PRC); Yihao LUO (Phoenix, Arizona); Min LONG (Phoenix, Arizona); Chenwei ZHENG (Tempe, Arizona) |
| ABSTRACT | The present invention relates to systems and methods for catalytic removal of oxidized contaminants (for example, nitrite, chromate, chlorate, trichloroethene, CFC-11, 4-nonylphenol, RDX, and perfluorooctanoate) from water and wastewater. In some aspects, the catalytic method of removing oxidized contaminants comprises using precious metal nanoparticles as catalysts to reduce the oxidized contaminants. |
| FILED | Thursday, June 17, 2021 |
| APPL NO | 18/002454 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/44 (20130101) B01J 23/46 (20130101) B01J 35/065 (20130101) B01J 37/18 (20130101) B01J 37/0072 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226605 | Grogan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Powdermet, Inc. (Euclid, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark Grogan (Cleveland, Ohio); Brian Doud (Cleveland Heights, Ohio); Andrew Sherman (Mentor, Ohio) |
| ABSTRACT | A heterogeneous composite consisting of near-nano ceramic clusters dispersed within a ductile matrix. The composite is formed through the high temperature compaction of a starting powder consisting of a core of ceramic nanoparticles held together with metallic binder. This core is clad with a ductile metal such that when the final powder is consolidated, the ductile metal forms a tough, near-zero contiguity matrix. The material is consolidated using any means that will maintain its heterogeneous structure. |
| FILED | Tuesday, November 22, 2022 |
| APPL NO | 17/992400 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/17 (20220101) B22F 3/14 (20130101) B22F 3/15 (20130101) B22F 3/17 (20130101) B22F 3/18 (20130101) B22F 3/20 (20130101) B22F 3/24 (20130101) B22F 3/105 (20130101) Original (OR) Class Working of Metal by the Action of a High Concentration of Electric Current on a Workpiece Using an Electrode Which Takes the Place of a Tool; Such Working Combined With Other Forms of Working of Metal B23H 1/08 (20130101) B23H 5/04 (20130101) B23H 5/12 (20130101) B23H 7/00 (20130101) Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 13/02 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/5626 (20130101) C04B 35/58014 (20130101) Alloys C22C 29/00 (20130101) C22C 29/005 (20130101) C22C 29/08 (20130101) C22C 29/14 (20130101) C22C 29/065 (20130101) C22C 32/00 (20130101) Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 17/00 (20130101) F16C 33/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226724 | FAHEY, JR. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Richard L. FAHEY, JR. (St. Louis, Missouri); Vincenzo MISURACA (Ballwin, Missouri); Reed SEARCY (St. Louis, Missouri) |
| ABSTRACT | A method for making a composite part using a reformable mandrel, including contouring a reformable mandrel; placing an uncured composite part on the reformable mandrel; curing the uncured composite part; and removing the reformable mandrel, wherein the reformable mandrel includes a core including a transitional state material having a transition temperature, and a sleeve at least partially surrounding the core and including a heat-resistant flexible material having an operational temperature. |
| FILED | Wednesday, January 19, 2022 |
| APPL NO | 17/648366 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 33/40 (20130101) B29C 33/505 (20130101) Original (OR) Class B29C 70/54 (20130101) B29C 70/342 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/3076 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230226807 | Percec et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Temple University-Of The Commonwealth Systemof Higher Education (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Simona Percec (Philadelphia, Pennsylvania); Jacob Celli (Drexei Hill, Panama); Fei Ren (Philadelphia, Pennsylvania) |
| ABSTRACT | Polymer composites may be made by providing a first polymer material; treating the first polymer material; providing a second polymer material; and pressing the first polymer material and the second polymer material. The polymer composites may be incorporated into ballistic resistant materials and soft armor articles. |
| FILED | Friday, May 07, 2021 |
| APPL NO | 17/998170 |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/024 (20130101) B32B 27/12 (20130101) Original (OR) Class B32B 27/16 (20130101) B32B 27/32 (20130101) B32B 27/34 (20130101) B32B 2250/24 (20130101) B32B 2262/0269 (20130101) B32B 2323/10 (20130101) B32B 2323/043 (20130101) B32B 2323/046 (20130101) B32B 2571/02 (20130101) Compositions of Macromolecular Compounds C08L 23/06 (20130101) C08L 23/26 (20130101) C08L 77/10 (20130101) C08L 2203/12 (20130101) C08L 2207/07 (20130101) C08L 2207/062 (20130101) C08L 2207/064 (20130101) C08L 2207/068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227305 | Painter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Oskar Painter (Sierra Madre, California); Jie Luo (Pasadena, California); Michael T. Fang (Pasadena, California); Alp Sipahigil (Pasadena, California); Paul B. Dieterle (Somerville, Massachusetts); Mahmoud Kalaee (Pasadena, California); Johannes M. Fink (Klosterneuburg, Austria); Andrew J. Keller (Los Angeles, California); Gregory MacCabe (Los Angeles, California); Hengjiang Ren (Pasadena, California); Justin D. Cohen (Annandale, Virginia) |
| ABSTRACT | Embodiments described herein include systems and techniques for converting (i.e., transducing) a quantum-level (e.g., single photon) signal between the three wave forms (i.e., optical, acoustic, and microwave). A suspended crystalline structure is used at the nanometer scale to accomplish the desired behavior of the system as described in detail herein. Transducers that use a common acoustic intermediary transform optical signals to acoustic signals and vice versa as well as microwave signals to acoustic signals and vice versa. Other embodiments described herein include systems and techniques for storing a qubit in phonon memory having an extended coherence time. A suspended crystalline structure with specific geometric design is used at the nanometer scale to accomplish the desired behavior of the system. |
| FILED | Tuesday, March 21, 2023 |
| APPL NO | 18/187419 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/40 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227508 | Voigt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Christopher A. Voigt (Belmont, Massachusetts); Andrew King (Cambridge, Massachusetts); Emerson Glassey (Malden, Massachusetts) |
| ABSTRACT | Disclosed herein, in some embodiments, non-naturally occurring proteins (e.g., non-naturally occurring modified proteins) that may be useful in the treatment of bacterial and viral infections, including SARS-CoV-2 infection, host cells comprising the same, and methods of treating bacterial and viral infections including SARS-CoV-2 infection. Also provided herein are host cells comprising fusion proteins for split intein-based selection of peptides that bind a target protein, methods of using the same, and methods of identifying peptides that bind a target protein. |
| FILED | Friday, June 11, 2021 |
| APPL NO | 18/009357 |
| CURRENT CPC | Peptides C07K 14/32 (20130101) Original (OR) Class C07K 2319/92 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1055 (20130101) C12N 15/1086 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227685 | WEBSTER et al. |
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| FUNDED BY |
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| APPLICANT(S) | NDSU RESEARCH FOUNDATION (Fargo, North Dakota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dean C. WEBSTER (FARGO, North Dakota); Mukund P' Sibi (Fargo, North Dakota); Jingbo Wu (Fargo, North Dakota); Catherine A. Sutton (Fargo, North Dakota) |
| ABSTRACT | The invention relates to a curable coating composition comprising: at least one acrylate functional oligomer; at least one furan-based reactive diluent; and at least one photoinitiator. The invention also relates to methods of making and using the curable coating composition of the invention. The invention also relates to a method for improving the hardness, abrasion resistance, and/or durability of an object or a substrate. |
| FILED | Tuesday, November 01, 2022 |
| APPL NO | 18/051678 |
| CURRENT CPC | Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 7/20 (20180101) C09D 7/63 (20180101) C09D 133/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227815 | Chatterjee et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anushree Chatterjee (Lafayette, Colorado); Thomas Aunins (Boulder, Colorado) |
| ABSTRACT | The present inventions describes a Facile Accelerated Specific Therapeutic (FAST) pipeline to rapidly design, built and test peptide nucleic acid treatments against mammalian or microbial genes of interest. The invention may include a bioinformatics application for facile and accelerated high throughput design of peptide nucleic acids (PNAs) that act as inhibitors of expression of specific targeted genes by binding to their mRNA to block translation, or PNA activators that can activate expression of target genes by binding to the respective promoter regions and recruitment of transcriptional activators. The invention may further involve automated and high throughput parallel synthesis of a PNA inhibitor/activator library for generation of on-site therapeutic molecules, which may reduce storage requirements, and the development of efficient delivery of therapeutic PNAs to host cells to overcome challenges of transport, toxicity, and bioavailability. The invention may further involve the testing of designed and built PNAs in a high throughput manner in a relevant infection, or mammalian cell culture model. The proposed invention may allow identification of important gene targets, and quickly generate translatable therapies that can be tested under host conditions, and most importantly develop a countermeasure platform that can be deployed on-site in the future to generate therapies in short time scales. |
| FILED | Monday, August 10, 2020 |
| APPL NO | 17/633735 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/67 (20130101) C12N 15/1093 (20130101) Original (OR) Class Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 30/06 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 15/30 (20190201) G16B 35/20 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227860 | Pandit et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambrige, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Shalmalee Pandit (Cambridge, Massachusetts); Angela Belcher (Lexington, Massachusetts) |
| ABSTRACT | A system for biofuel production can include a cell, a nanoparticle on a surface of the cell, and an irradiation unit configured to expose the cell to irradiation. A method of producing biofuel can include providing a cell having a nanoparticle on a surface of the cell, exposing the cell to a fuel precursor, irradiating the cell, converting the fuel precursor to a biofuel with the cell, and collecting the biofuel. |
| FILED | Wednesday, June 09, 2021 |
| APPL NO | 18/001032 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227864 | Lynch et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Michael David Lynch (Durham, North Carolina); Shuai Li (Durham, North Carolina) |
| ABSTRACT | The present disclosure is related to genetically engineered microbial strains and related bioprocesses for the production of products from acetyl-CoA. Specifically, the use of dynamically controlled synthetic metabolic valves to reduce the activity of certain enzymes, leads to increased product production in a two-stage process. |
| FILED | Friday, July 23, 2021 |
| APPL NO | 18/006506 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) C12N 9/0008 (20130101) C12N 9/0067 (20130101) C12N 9/1025 (20130101) C12N 15/11 (20130101) C12N 15/70 (20130101) C12N 15/635 (20130101) C12N 2310/20 (20170501) C12N 2800/101 (20130101) C12N 2830/001 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/44 (20130101) Original (OR) Class Enzymes C12Y 101/01049 (20130101) C12Y 102/04001 (20130101) C12Y 112/07002 (20130101) C12Y 203/03001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227955 | Holder et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Scott M. Holder (Cherry Hill, New Jersey); Dale J. Weires (Hockessin, Delaware) |
| ABSTRACT | Methods of hardening a case-nitrided metal article, methods of producing a hardened case-nitrided metal article, and hardened case-nitrided metal articles. The methods of hardening a case-nitrided metal article include heating the case-nitrided metal article to an aging temperature, maintaining the case-nitrided metal article at the aging temperature for an aging time, and cooling the case-nitrided metal article from the aging temperature. The methods of producing a hardened case-nitrided metal article include case-nitriding a metal article to produce a case-nitrided metal article and subsequently hardening the case-nitrided metal article. The hardened case-nitrided metal article comprises a body formed of a metal or a metal alloy, a surface surrounding the body, and a nitrided case layer formed in the body and extending inwardly from the surface of the body toward the core that includes a hardness that is greater than that of an otherwise equivalent case-nitrided metal article. |
| FILED | Monday, March 13, 2023 |
| APPL NO | 18/183012 |
| CURRENT CPC | Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/183 (20130101) Original (OR) Class Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 8/24 (20130101) C23C 8/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230228200 | Heeter |
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| FUNDED BY |
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| APPLICANT(S) | Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert W. Heeter (Noblesville, Indiana) |
| ABSTRACT | An engine section stator for a gas turbine engine having a compressor, a combustor, and a turbine. The engine section stator includes an inner band, an outer band spaced radially outwardly from the inner band, and a series of spaced apart aerofoils extending the inner and outer bands. The engine section stator includes a stiffness feature that extends away from one of the inner and outer bands of the engine section stator. The stiffness feature configured to increase the high cycle fatigue strength of the aerofoils without impeding airflow passing between the inner and outer bands. |
| FILED | Wednesday, January 19, 2022 |
| APPL NO | 17/578885 |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/041 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/121 (20130101) F05D 2300/501 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230228568 | Rastegar |
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| FUNDED BY |
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| APPLICANT(S) | Omnitek Partners LLC (Ronkonkoma, New York) |
| ASSIGNEE(S) | Omnitek Partners LLC (Ronkonkoma, New York) |
| INVENTOR(S) | Jahangir S Rastegar (Stony Brook, New York) |
| ABSTRACT | A system including a polarized RF scanning reference source and one or more cavity sensor receivers. |
| FILED | Saturday, March 18, 2023 |
| APPL NO | 18/123261 |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/38 (20130101) Original (OR) Class G01C 19/48 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 1/045 (20130101) G01S 5/0221 (20130101) G01S 5/0247 (20130101) G01S 7/024 (20130101) G01S 13/88 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230228672 | MORALES et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rocky G. MORALES (Long Beach, California); Aileen O. HUI (Los Angeles, California); De-Ling LIU (Manhattan Beach, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Rocky G. MORALES (Long Beach, California); Aileen O. HUI (Los Angeles, California); De-Ling LIU (Manhattan Beach, California) |
| ABSTRACT | A multi-purpose in-situ contamination sampler includes an inner frame surrounded by a plurality of removable or attachable pieces, each of which include of a single witness surface configured to collect both particulate and molecular contamination within an environment on a payload or a spacecraft. |
| FILED | Thursday, January 06, 2022 |
| APPL NO | 17/570302 |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/66 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/211 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 21/0004 (20130101) G02B 21/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230228869 | Miller et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America ,as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Gerald F Miller (Bedford, Indiana); James L Stewart (Bloomington, Indiana); William F Crespo-Miranda (Bloomington, Indiana); Donald R Statter, JR. (Lousby, Maryland) |
| ABSTRACT | Generally, the present disclosure relates to a forward deployed sensor system or, in a specific embodiment, a forward deployed radar (FDR) system. The forward deployed sensor system includes a radar system and may also include other types of sensors such as optical sensors, acoustic sensors including sonar, and electromagnetic sensors. Further, the forward deployed sensor system may also include a communication system such as a full spectrum receiver/transmitter, a ship to ship relay transponder, a satellite communication system, and global positioning system (GPS) capability. The forward deployed sensor system is able to detect objects in the air, on the sea, and underwater, and communicate such detection to a ship, submarine, aircraft, satellite, or other remote location. Such systems may be used to augment the protection of shipping lanes by military or security forces to allow for peaceful commerce and utility of the sea by all nations. |
| FILED | Monday, January 09, 2023 |
| APPL NO | 18/094629 |
| CURRENT CPC | Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/04 (20130101) B63G 8/08 (20130101) B63G 8/22 (20130101) B63G 8/38 (20130101) B63G 8/39 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/003 (20130101) G01S 7/027 (20210501) G01S 13/86 (20130101) G01S 13/862 (20130101) G01S 13/917 (20190501) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230229173 | Christensen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Textron Innovations Inc. (Providence, Rhode Island) |
| ASSIGNEE(S) | Textron Innovations Inc. (Providence, Rhode Island) |
| INVENTOR(S) | Kevin Thomas Christensen (Plano, Texas); Sang Gyun Park (Southlake, Texas) |
| ABSTRACT | Automatic low-speed aircraft maneuver wind compensation is implemented by an aircraft flight control system flight control computer (FCC) configured to receive or retrieve steady wind data and retrieve groundspeed data for the aircraft. The FCC computes two-dimensional relative horizontal airspeed (i.e., horizontal relative to the surface of the earth) for the aircraft, using the steady wind data and the groundspeed data for the aircraft, and computes relative changes in trim controls of the aircraft using the two-dimensional relative horizontal airspeed of the aircraft. The resulting relative changes in controls of the aircraft due to relative horizontal airspeed changes are applied to flight element control actuators. |
| FILED | Tuesday, January 18, 2022 |
| APPL NO | 17/578058 |
| CURRENT CPC | Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 5/00 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/106 (20190501) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230230256 | Johnson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| INVENTOR(S) | Benjamin Lee Johnson (Brooklyn Park, Minnesota); Vibhor L Bageshwar (Minneapolis, Minnesota); Srivatsan Varadarajan (St. Louis Park, Minnesota) |
| ABSTRACT | In one embodiment, a vision aided navigation system comprises: at least one image sensor configured to produce image frames of a surrounding environment; a feature extractor configured to extract at least one image feature from a first image frame; a navigation filter configured to output a navigation solution based navigation data from a navigation device and changes in position of the image feature in the images; a feature tracker to receive the image frames and predict a location of the image feature in a subsequent image frame; a dynamic localized parameter adjuster to adjust at least one image parameter of the subsequent image frame; and wherein the feature tracker is configured so that when the image feature cannot be identified in the subsequent image frame within a bounded region around the predicted location, the dynamic localized parameter adjuster adjusts the at least one image parameter within the bounded region. |
| FILED | Thursday, May 30, 2019 |
| APPL NO | 16/426733 |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/3623 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/73 (20170101) G06T 7/246 (20170101) G06T 2207/30252 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230230680 | Ward et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kevin Ward (Glen Allen, Virginia); Daniel Francis Taylor (Belleville, Michigan); Michael W. Sjoding (Ann Arbor, Michigan); Christopher Elliot Gillies (Ann Arbor, Michigan) |
| ABSTRACT | A computing system includes a processor; and a memory having stored thereon an adjustment application comprising computer-executable instructions that, when executed, cause the computing system to: display a graphical user interface including a digital medical image of a patient; superimpose a bounding box; receive an adjustment of an area of interest; and provide an adjusted digital medical image. A non-transitory computer-readable medium includes computer-executable instructions that, when executed via one or more processors, cause a computer to: display a graphical user interface including a digital medical image of a patient; superimpose a bounding box; receive an adjustment of an area of interest; and provide an adjusted digital medical image. A computer-implemented method includes: displaying a graphical user interface including a digital medical image of a patient; superimposing a bounding box; receiving an adjustment of an area of interest; and providing an adjusted digital medical image. |
| FILED | Tuesday, March 07, 2023 |
| APPL NO | 18/180119 |
| CURRENT CPC | Electric Digital Data Processing G06F 17/18 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 11/20 (20130101) G06T 2207/10116 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30061 (20130101) G06T 2210/12 (20130101) Image or Video Recognition or Understanding G06V 10/25 (20220101) G06V 10/82 (20220101) G06V 10/454 (20220101) G06V 10/987 (20220101) G06V 10/7784 (20220101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 30/40 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230230851 | KHAN et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | ASIF KHAN (IRMO, South Carolina); MVS CHANDRASHEKHAR (COLUMBIA, South Carolina); MD DIDARUL ALAM (WEST COLUMBIA, South Carolina); MIKHAIL E. GAEVSKI (MOUNT SINAI, New York) |
| ABSTRACT | The present disclosure relates to use of 193-nm excimer laser-based lift-off (LLO) of Al0.26Ga0.74N/GaN High-electron mobility transistors (HEMTs) with thick (t>10 μm) AlN heat spreading buffer layers grown over sapphire substrates. The use of the thick AlN heat spreading layer resulted in thermal resistance (Rth) of 16 Kmm/W for as-fabricated devices on sapphire, which is lower than the value of ≈25-50 Kmm/W for standard HEMT structures on sapphire without the heat-spreaders. Soldering the LLO devices onto a copper heat sink led to a further reduction of Rth to 8 Kmm/W, a value comparable to published measurements on bulk SiC substrates. The reduction in Rth by LLO and bonding to copper led to significantly reduced self-heating and drain current droop. A drain current density as high as 0.9 A/mm was observed despite a marginal reduction of the carrier mobility (≈1800 to ≈1500 cm2/Vs). This is the highest drain current density and mobility reported to-date for LLO AlGaN/GaN HEMTs. |
| FILED | Monday, November 14, 2022 |
| APPL NO | 17/986579 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02079 (20130101) H01L 21/4882 (20130101) Original (OR) Class H01L 21/7813 (20130101) H01L 23/3736 (20130101) H01L 29/205 (20130101) H01L 29/2003 (20130101) H01L 29/7786 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230231364 | Meyer et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Jerry R. Meyer (Catonsville, Maryland); Alexander Spott (Santa Barbara, California); Chul Soo Kim (West Springfield, Virginia); Mijin Kim (West Springfield, Virginia); Chadwick L. Canedy (Washington, District of Columbia); Charles D. Merritt (Fairfax, Virginia); William W. Bewley (Falls Church, Virginia); Igor Vurgaftman (Severna Park, Maryland) |
| ABSTRACT | Semiconductor laser architectures that provide weak index guiding of interband cascade lasers (ICLs) processed on a native III-V substrate and of ICLs grown on silicon or integrated on silicon by heterogeneous bonding. Weak index guiding of a ridge waveguide semiconductor laser can enhance the stability of lasing in the fundamental lateral mode, so as to allow a wider ridge to maintain stable single-lateral-mode operation. |
| FILED | Wednesday, January 04, 2023 |
| APPL NO | 18/149778 |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/3419 (20130101) Original (OR) Class H01S 5/3422 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230231412 | McAleenan |
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| FUNDED BY |
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| APPLICANT(S) | KAZAK TECHNOLOGIES INC. (Woolwich, Maine) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael McAleenan (Woolwich, Maine) |
| ABSTRACT | A flywheel includes a hub configured to rotate about a longitudinal axis. At least one member having a laminate casing connected to the hub, the laminate casing is formed with an enclosed space for housing at least one mass with a fixed shape. The enclosed space is structured to control radial displacement of the at least one mass. Wherein upon rotation, an operational radial force applies a through thickness laminate radial load to the laminate casing, while simultaneously radially displacing the at least one mass to apply a controllable compressive load on the laminate casing. The applied controllable compressive load increases a predetermined laminate loading capacity by an amount of compressive load counteracting the through thickness laminate radial load, resulting in a corresponding increase in a flywheel angular velocity, that therefore increases an amount of energy stored by the at least one energy storage unit. |
| FILED | Monday, January 23, 2023 |
| APPL NO | 18/158468 |
| CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 10/26 (20130101) Indexing Scheme Relating to Aspects Cross-cutting Vehicle Technology B60Y 2400/162 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 15/007 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230232123 | O'Toole et al. |
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| FUNDED BY |
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| APPLICANT(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew O'Toole (Pittsburgh, Pennsylvania); Mark Sheinin (Pittsburgh, Pennsylvania); Srinivasa Narasimhan (Pittsburgh, Pennsylvania) |
| ABSTRACT | A novel class of imaging systems that combines diffractive optics with 1D line sensing is disclosed. When light passes through a diffraction grating or prism, it disperses as a function of wavelength. This property is exploited to recover 2D and 3D positions from line images. A detailed image formation model and a learning-based algorithm for 2D position estimation are disclosed. The disclosure includes several extensions of the imaging system to improve the accuracy of the 2D position estimates and to expand the effective field-of-view. The invention is useful for fast passive imaging of sparse light sources, such as streetlamps, headlights at night and LED-based motion capture, and structured light 3D scanning with line illumination and line sensing. |
| FILED | Friday, May 28, 2021 |
| APPL NO | 17/925064 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/70 (20170101) G06T 7/90 (20170101) G06T 2207/10024 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30204 (20130101) Pictorial Communication, e.g Television H04N 23/56 (20230101) H04N 23/95 (20230101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230232350 | SHEN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intelligent Fusion Technology, Inc. (Germantown, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dan SHEN (Germantown, Maryland); Genshe CHEN (Germantown, Maryland); Khanh PHAM (Kirtland AFB, New Mexico); Erik BLASCH (Arlington, Virginia) |
| ABSTRACT | A system includes at least one slave node and one master node that are for a method of time synchronization between the at least one slave node and the master node. The method includes: sending, by one slave node, a first message to the master node to launch a time synchronization between the slave node and the master node; upon receiving the first message, adding, by the master node, a receiving time on a master clock to the first message to form a second message; sending, by the master node, the second message back to the slave node; adding, by the slave node, a receiving time on the slave clock to the second message to form an updated message; and performing, by the slave node, a time adjustment to the slave clock based on the updated message, thereby synchronizing time between the slave node and the master node. |
| FILED | Wednesday, January 19, 2022 |
| APPL NO | 17/579348 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) Transmission H04B 7/026 (20130101) Wireless Communication Networks H04W 56/0015 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230232561 | Cahall et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ColdQuanta, Inc. (Boulder, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Clinton Cahall (Lafayette, Colorado); Jayson Denney (Golden, Colorado); Thomas William Noel (Lafayette, Colorado); Hugo Leon (Longmont, Colorado); Steffen Michael Kross (Boulder, Colorado); James S. Hale (Longmont, Colorado); Colin Fitzgerald (Boulder, Colorado); Matthew Barton Jaskot (Golden, Colorado) |
| ABSTRACT | A vacuum cell including a vacuum chamber, a first bond, and a second bond is described. The first bond affixes a first portion of the vacuum cell to a second portion of the vacuum cell. The first bond has a first bonding temperature and a first debonding temperature greater than the first bonding temperature. The second bond affixes a third portion of the vacuum cell to a fourth portion of the vacuum cell. The second bond has a second bonding temperature and a second debonding temperature. The second bonding temperature is less than the first debonding temperature. |
| FILED | Tuesday, December 20, 2022 |
| APPL NO | 18/085501 |
| CURRENT CPC | Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/00 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 5/066 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230232641 | SHULAKER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Max SHULAKER (San Mateo, California); Mindy BISHOP (Waltham, Massachusetts) |
| ABSTRACT | Described are concepts, systems, circuits, devices, structures and methods for depositing carbon nanotubes (CNTs) uniformly over a substrate. The described concepts, systems, circuits, devices, structures and methods meet at least several requirements; namely, the systems, circuits, devices, structures are: (1) manufacturable; (2) silicon-CMOS compatible; and (3) provide a path for realizing energy efficiency benefits utilizing silicon. In embodiments, described is an illustrative CNT solution-based deposition technique that addresses all of these requirements. Also described is a method for providing carbon nanotube field effect transistors (CNFETs) using uniform and reproducible fabrication techniques suitable for use across industry-standard wafers and which may use the same equipment currently being used to fabricate silicon product wafers. Also described are CNFETs fabricated within commercial silicon manufacturing facilities and having wafer-scale uniformity and reproducibility across multiple wafers. |
| FILED | Friday, August 20, 2021 |
| APPL NO | 18/002495 |
| CURRENT CPC | Organic electric solid-state devices H10K 10/466 (20230201) H10K 10/484 (20230201) Original (OR) Class H10K 71/12 (20230201) H10K 71/441 (20230201) H10K 85/221 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20230227815 | Chatterjee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anushree Chatterjee (Lafayette, Colorado); Thomas Aunins (Boulder, Colorado) |
| ABSTRACT | The present inventions describes a Facile Accelerated Specific Therapeutic (FAST) pipeline to rapidly design, built and test peptide nucleic acid treatments against mammalian or microbial genes of interest. The invention may include a bioinformatics application for facile and accelerated high throughput design of peptide nucleic acids (PNAs) that act as inhibitors of expression of specific targeted genes by binding to their mRNA to block translation, or PNA activators that can activate expression of target genes by binding to the respective promoter regions and recruitment of transcriptional activators. The invention may further involve automated and high throughput parallel synthesis of a PNA inhibitor/activator library for generation of on-site therapeutic molecules, which may reduce storage requirements, and the development of efficient delivery of therapeutic PNAs to host cells to overcome challenges of transport, toxicity, and bioavailability. The invention may further involve the testing of designed and built PNAs in a high throughput manner in a relevant infection, or mammalian cell culture model. The proposed invention may allow identification of important gene targets, and quickly generate translatable therapies that can be tested under host conditions, and most importantly develop a countermeasure platform that can be deployed on-site in the future to generate therapies in short time scales. |
| FILED | Monday, August 10, 2020 |
| APPL NO | 17/633735 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/67 (20130101) C12N 15/1093 (20130101) Original (OR) Class Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 30/06 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 15/30 (20190201) G16B 35/20 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230228610 | RAMSEY |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RAPA Technologies, LLC (Meriden, New Hampshire) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Marc C. RAMSEY (Meriden, New Hampshire) |
| ABSTRACT | Systems and methods for storing fluid are described. In some embodiments, a system may include a container having an internal volume that is configured to change as fluid enters or exits, a first shell component, and a second shell component. The first shell component may limit an expansion of the container in a first direction, and the second shell component may limit the expansion of the container in a second direction that is opposite the first direction. |
| FILED | Tuesday, January 17, 2023 |
| APPL NO | 18/155262 |
| CURRENT CPC | Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 23/241 (20130101) Original (OR) Class G01F 23/248 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230228856 | Reinhardt |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Dayton Research Institute (Dayton, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew Reinhardt (Ironton, Ohio) |
| ABSTRACT | A system for calibrating a light detection and ranging (LiDAR) sensor comprises an optical transmission source, a coarse adjustment optically coupled to the optical transmission source, an optical device optically coupled to the coarse adjustment, a fine adjustment optically coupled to the optical device, and a lens optically coupled to the fine adjustment. Light from the optical transmission source passes through the coarse adjustment, the optical device, the fine adjustment, and the lens to illuminate a LiDAR sensor under test. Further, a single optical transmission source, coarse adjustment, and optical device may be coupled to a splitter to test multiple LiDAR sensors at once, where each LiDAR sensor is associated with an individually controlled fine attenuator and an individually controlled variable lens. |
| FILED | Tuesday, January 17, 2023 |
| APPL NO | 18/155426 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/497 (20130101) Original (OR) Class G01S 17/894 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20230226089 | KOFF et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Atropos Therapeutics, Inc. (San Carlos, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew KOFF (Westbury, New York); Thomas B. NGUYEN (Missouri City, Texas) |
| ABSTRACT | The present disclosure relates to a method of treating or delaying onset of a disease associated with the accumulation of senescent cells in a subject comprising administering to the subject a therapeutically effective amount of a senosuppressor that modulates a number of ATRX foci per cell. |
| FILED | Monday, March 20, 2023 |
| APPL NO | 18/186412 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/65 (20130101) A61K 31/519 (20130101) A61K 31/704 (20130101) Original (OR) Class A61K 31/4709 (20130101) A61K 35/28 (20130101) A61K 36/53 (20130101) A61K 36/70 (20130101) A61K 36/79 (20130101) A61K 36/258 (20130101) A61K 36/488 (20130101) A61K 36/804 (20130101) A61K 36/815 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227443 | Barbosa |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GB006, INC. (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Antonio J. Barbosa (Ave Maria, Florida) |
| ABSTRACT | The present invention provides new salts and crystalline forms of leukadherin LA1 [(Z)-4-(5-((3-benzyl-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-yl)benzoic acid] according to Formula I. Methods for preparation of the salts and crystalline forms are also described, as well as methods for treating β2 integrin-mediated diseases and conditions using the salts and crystalline forms. |
| FILED | Tuesday, November 01, 2022 |
| APPL NO | 17/978848 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/13 (20130101) Acyclic or Carbocyclic Compounds C07C 215/08 (20130101) Heterocyclic Compounds C07D 417/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230227631 | Keith et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MITO Material Solutions, Inc. (Indiana, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kevin Keith (Carmel, Indiana); Bhishma Sedai (Stillwater, Oklahoma) |
| ABSTRACT | A high-performance composite material is provided including a polymer and a hybrid nanoadditive dispersed throughout the polymer at a low concentration and without agglomeration. The hybrid nanoadditive includes a first, graphene oxide portion and a second, polyhedral oligomeric silesquioxane (POSS) portion. Associated extrusion systems and methods are also provided. |
| FILED | Tuesday, June 15, 2021 |
| APPL NO | 18/010379 |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/226 (20130101) C08J 2363/00 (20130101) C08J 2377/06 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/549 (20130101) Original (OR) Class C08K 2201/005 (20130101) C08K 2201/011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20230225326 | Bowden et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| ASSIGNEE(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| INVENTOR(S) | Ned B. Bowden (Iowa City, Iowa); Justin M. CARTER (Iowa City, Iowa); Eric M. BROWN (Iowa City, Iowa); Nimesh RANASINGHE (Iowa City, Iowa); Arjun PAUDEL (Iowa City, Iowa); Erin E. IRISH (Iowa City, Iowa) |
| ABSTRACT | The invention provides a compound of formula I: wherein X, Y, Z, R′, R2, and X+ have any of the values described in the specification. The compounds are useful to increase plant growth and/or to increase harvest yield. |
| FILED | Tuesday, February 28, 2023 |
| APPL NO | 18/115700 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 57/12 (20130101) Original (OR) Class A01N 59/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230225329 | KONG |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (Blacksburg, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ping KONG (Virginia Beach, Virginia) |
| ABSTRACT | The disclosure, in one aspect, relates to compositions containing non-pathogenic Burkholderia species SSG and/or extracts from SSG cultures and methods of making and using the same. Also disclosed are methods for treating and preventing plant diseases caused by pathogens, the methods including applying the disclosed compositions to plants and/or soil, diseased leaf debris, or other plant growth media surrounding the plants. Finally, disclosed are methods for increasing plant growth using the disclosed compositions. The compositions are effective as well as environmentally benign and are not detrimental to human or animal health This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure. |
| FILED | Wednesday, March 03, 2021 |
| APPL NO | 17/905283 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/20 (20200101) Original (OR) Class Biocidal, Pest Repellant, Pest Attractant or Plant Growth Regulatory Activity of Chemical Compounds or Preparations A01P 3/00 (20210801) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Education (ED)
| US 20230230484 | Al Faruque et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mohammad Abdullah Al Faruque (Irvine, California); Shih-Yuan Yu (Irvine, California); Arnav Vaibhav Malawade (Irvine, California); Deepan Muthirayan (Irvine, California); Pramod P. Khargonekar (Irvine, California) |
| ABSTRACT | The present invention is directed to a Spatiotemporal scene-graph embedding methodology that models scene-graphs and resolves safety-focused tasks for autonomous vehicles. The present invention features a computing system comprising instructions for accepting the one or more images, extracting one or more objects from each image, computing an inverse-perspective mapping transformation of the image to generate a bird's-eye view (BEV) representation of each image, calculating relations between each object for each image, and generating a scene-graph for each image based on the aforementioned calculations. The system may further comprise instructions for calculating a confidence value for whether or not a collision will occur through the generation of a spatio-temporal graph embedding based on a spatial graph embedding and a temporal model. |
| FILED | Monday, January 16, 2023 |
| APPL NO | 18/154987 |
| CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 30/0956 (20130101) B60W 60/0015 (20200201) B60W 2420/42 (20130101) B60W 2552/00 (20200201) B60W 2554/402 (20200201) B60W 2554/4041 (20200201) Traffic Control Systems G08G 1/166 (20130101) Original (OR) Class G08G 1/167 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20230225824 | Fares |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sam S. Fares (Brooklyn, New York) |
| ABSTRACT | Disclosed herein is a portable aerosol-protective apparatus and method for reducing the exposure of healthcare workers to contaminants and aerosols that may contain respiratory and other pathogens. The apparatus generally comprises a shield suitable for forming a partial enclosure around the head-space end of a hospital or surgery bed, through which a medical procedure can be performed on a patient. The method generally comprises performing the medical procedure on the patient through the shield of the disclosed apparatus. |
| FILED | Wednesday, June 02, 2021 |
| APPL NO | 18/007622 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 90/40 (20160201) Original (OR) Class A61B 2090/401 (20160201) A61B 2560/0437 (20130101) Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices A61G 10/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 20230226188 | Monson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bexion Pharmaceuticals Inc. (Covington, Kentucky) |
| ASSIGNEE(S) | Bexion Pharmaceuticals Inc. (Covington, Kentucky) |
| INVENTOR(S) | Ellen K. Monson (Cincinnati, Ohio); Xiaochen Wei (Covington, Kentucky); Ray Takigiku (Covington, Kentucky); Charles A. Cruze, III (West Chester, Ohio); Joseph W. Wyse (Nicholasville, Kentucky) |
| ABSTRACT | Disclosed are pharmaceutical compositions containing saposin C and phosphatidylserine that are useful for treating various cancers. |
| FILED | Friday, January 20, 2023 |
| APPL NO | 18/157689 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/19 (20130101) A61K 9/127 (20130101) A61K 38/18 (20130101) A61K 47/10 (20130101) A61K 47/12 (20130101) Original (OR) Class A61K 47/18 (20130101) A61K 47/24 (20130101) A61K 47/26 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/4705 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/40 (20130101) C12Q 2334/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 20230226188 | Monson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bexion Pharmaceuticals Inc. (Covington, Kentucky) |
| ASSIGNEE(S) | Bexion Pharmaceuticals Inc. (Covington, Kentucky) |
| INVENTOR(S) | Ellen K. Monson (Cincinnati, Ohio); Xiaochen Wei (Covington, Kentucky); Ray Takigiku (Covington, Kentucky); Charles A. Cruze, III (West Chester, Ohio); Joseph W. Wyse (Nicholasville, Kentucky) |
| ABSTRACT | Disclosed are pharmaceutical compositions containing saposin C and phosphatidylserine that are useful for treating various cancers. |
| FILED | Friday, January 20, 2023 |
| APPL NO | 18/157689 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/19 (20130101) A61K 9/127 (20130101) A61K 38/18 (20130101) A61K 47/10 (20130101) A61K 47/12 (20130101) Original (OR) Class A61K 47/18 (20130101) A61K 47/24 (20130101) A61K 47/26 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/4705 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/40 (20130101) C12Q 2334/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 20230226862 | Shiu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Leung Man Shiu (Gaithersburg, Maryland); Edward F. Houston (Bristow, Virginia); Anthony B. Taylor (Stafford, Virginia); Tuyen Thanh Nguyen (Fairfax, Virginia); Scott R. Bombaugh (Burke, Virginia) |
| ABSTRACT | This disclosure relates to systems and methods of towing, hitching, and connecting devices. In particular, this disclosure relates to tow devices, hitches, and connections for towing item containers behind vehicles, both autonomous and manually guided. |
| FILED | Tuesday, March 28, 2023 |
| APPL NO | 18/191386 |
| CURRENT CPC | Vehicle Connections B60D 1/14 (20130101) Original (OR) Class B60D 1/52 (20130101) B60D 2001/001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 20230228202 | Packer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Travis J. Packer (Evendale, Ohio); Michael A. Hile (Evendale, Ohio); James H. Grooms (Evendale, Ohio) |
| ABSTRACT | Methods, apparatus, systems, and articles of manufacture are disclosed to implement a stator plenum with collet seal. The stator plenum for a gas turbine engine includes an outer shell circumscribing a centerline axis, a first end of the outer shell coupled to an engine casing at a first coupling, the first coupling to form a first seal, a second end of the outer shell coupled to the engine casing at a second coupling, the second end formed by a thickened portion of the outer shell, the second coupling to form a second seal, and a cavity formed by the outer shell, the cavity to contain cooling flow to reduce a temperature of a turbine. |
| FILED | Thursday, January 20, 2022 |
| APPL NO | 17/580426 |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/041 (20130101) F01D 9/065 (20130101) Original (OR) Class F01D 11/001 (20130101) F01D 11/025 (20130101) F01D 25/246 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230230758 | Pérez-Díaz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | COUNTERFOG CORPORATION (Irving, Texas); XTRACTION SCIENCE AND TECHNOLOGY, INC. (South Park, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | José Luis Pérez-Díaz (Valdemoro, Spain); Steven A. Cotten (Lockport, New York) |
| ABSTRACT | Disclosed is a design approach for intrinsically safe electromagnetic devices such as electrically actuated valves, motors, generators, or transformers intended for and capable of safe operation in explosive atmospheres or environments. The design employs a plurality of electrically insulated, intrinsically safe circuits cooperating to induce, or in the case of a generator, create a relatively large magnetic flux in the ferromagnetic core, or iron, of these devices. A method to construct such intrinsically safe devices is disclosed. These devices can be practically used in machines, mechanisms, valves, and manned or unmanned vehicles intended for safe operation in hazardous environments, for example underground coal mines or ATEX or EX classified facilities. |
| FILED | Friday, January 14, 2022 |
| APPL NO | 17/576415 |
| CURRENT CPC | Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 31/04 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 7/081 (20130101) H01F 27/24 (20130101) H01F 27/30 (20130101) Original (OR) Class Dynamo-electric Machines H02K 11/30 (20160101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230231178 | Amatucci et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Glenn Amatucci (Peapack, New Jersey); Irene Plitz (Toms River, New Jersey); Linda Sung (Morris Plains, New Jersey); Anthony Ferrer (Red Lion, New Jersey) |
| ABSTRACT | An electrochemical cell is provided comprising a thin metal foil packaging made from at least one sheet of metal foil and having a perimeter extending around at least a portion of the electrochemical cell, as well as an electrochemical cell stack contained within the thin metal foil packaging, and a metal-to-metal welded seal around at least a portion of the perimeter of the thin metal foil packaging. The metal-to-metal welded seal is hermetic or nearly hermetic. Furthermore, the metal-to-metal welded seal is narrow, having a width of less than about 1 mm, and is less than about 5 mm away from the electrochemical cell stack. In some embodiments, the thin metal foil packaging functions not only as a hermetically or near hermetically sealed packaging, but also as either the negative or positive current collector, with one electrode of the cell bonded to the foil packaging. A method for making the foregoing electrochemical cell is also provided and involves using laser energy the metal-to-metal welded seal, wherein the laser energy is applied to the foil at high speed using a scanning laser. |
| FILED | Thursday, March 23, 2023 |
| APPL NO | 18/125550 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/133 (20130101) H01M 4/661 (20130101) H01M 10/058 (20130101) H01M 10/0525 (20130101) Original (OR) Class H01M 10/0585 (20130101) H01M 50/105 (20210101) H01M 50/119 (20210101) H01M 50/133 (20210101) H01M 50/545 (20210101) H01M 2220/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
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Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-applications-20230720.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page