FedInvent™ Patent Applications
Application Details for Thursday, August 10, 2023
This page was updated on Thursday, August 10, 2023 at 06:46 AM GMT
Department of Health and Human Services (HHS)
| US 20230247982 | Joseph et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Cincinnati (Cincinnati, Ohio) |
| ASSIGNEE(S) | University of Cincinnati (Cincinnati, Ohio) |
| INVENTOR(S) | Bernardin Joseph (Cincinnati, Ohio); Kasiemobi Pulliam (Cincinnati, Ohio); Timothy A Pritts (Cincinnati, Ohio); Salwa Arafa (Liberty Twp, Ohio); Charles Caldwell (Cincinnati, Ohio); Alex Lentsch (Hebron, Kentucky); Michael Goodman (Cincinnati, Ohio) |
| ABSTRACT | A storage solution for packed red blood cells is disclosed where the solution is alkaline and has a viscosity at 4° C. greater than about 20 millipascal seconds. In one embodiment, the storage solution comprises from about 0.1 percent to about 10 percent of hydroxy-propyl-methyl-cellulose. In another embodiment, the storage solution has a pH greater than about 8. |
| FILED | Tuesday, July 13, 2021 |
| APPL NO | 18/015158 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0226 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0641 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230248090 | SHI |
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| FUNDED BY |
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| APPLICANT(S) | WUXI CENTER FOR DISEASE CONTROL AND PREVENTION (Wuxi City, China PRC) |
| ASSIGNEE(S) | WUXI CENTER FOR DISEASE CONTROL AND PREVENTION (Wuxi City, China PRC) |
| INVENTOR(S) | Chao SHI (Wuxi City, China PRC) |
| ABSTRACT | Medical protective clothing, including a protective clothing body. The protective clothing body includes a hood part, a neck part, a top, pants, shoe cover parts, and sleeves, and is formed by sewing the hood part, the neck part, the top, the pants, the shoe cover parts and the sleeves in sequence. The hood part includes an air exchange assembly. The sidewall of the top is separated from the back of the medical personnel by means of airbag ribs, thus preventing the sweaty back from being in contact with the sidewall of the top to make the people feel uncomfortable when the protective clothing is worn for a long time in summer. |
| FILED | Thursday, February 09, 2023 |
| APPL NO | 18/107857 |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 13/1218 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230248602 | ZELIK et al. |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
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| INVENTOR(S) | Karl ZELIK (Nashville, Tennessee); Jaime FINE (Clarksville, Tennessee); Anna WOLFE (Nashville, Tennessee) |
| ABSTRACT | Wearable assistance devices and methods of using the same are disclosed. Embodiments relate to bimodal wearable assistance devices that provide assistance in one mode, and no or reduced assistance in a second mode, for reducing muscle stress, fatigue, injury and/or pain in the lower back or other body segments, and enabling comfortable, free or increased range of motion. Other embodiments relate to interfaces for wearable assistance devices that can loosen/tighten. |
| FILED | Wednesday, June 16, 2021 |
| APPL NO | 18/010756 |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/0244 (20130101) A61H 3/00 (20130101) Original (OR) Class A61H 2201/163 (20130101) A61H 2201/1253 (20130101) A61H 2201/1616 (20130101) A61H 2201/1626 (20130101) A61H 2201/1652 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230248649 | ZHANG |
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| APPLICANT(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| INVENTOR(S) | Huang-Ge ZHANG (Louisville, Kentucky) |
| ABSTRACT | An exosomal composition is provided that includes a therapeutic agent encapsulated by an exosome. The therapeutic agent can be a phytochemical agent, a chemotherapeutic agent, or a Stat3 inhibitor. Pharmaceutical compositions comprising the exosomal compositions are also provided. Methods for treating an inflammatory disease or a cancer are further provided and include administering an effective amount of an exosomal composition to a subject in need thereof to thereby treat the inflammatory disorder or the cancer. |
| FILED | Friday, March 31, 2023 |
| APPL NO | 18/129593 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) Original (OR) Class A61K 31/05 (20130101) A61K 31/12 (20130101) A61K 31/282 (20130101) A61K 31/337 (20130101) A61K 31/353 (20130101) A61K 31/475 (20130101) A61K 31/513 (20130101) A61K 31/575 (20130101) A61K 31/704 (20130101) A61K 33/243 (20190101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230248680 | Reddy et al. |
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| APPLICANT(S) | Icahn School of Medicine at Mount Sinai (New York, New York) |
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| INVENTOR(S) | Premkumar Reddy (New York, New York); Kris White (New York, New York); M.V. Ramana Reddy (New York, New York); Adolfo Garcia-Sastre (New York, New York) |
| ABSTRACT | Provided herein are methods for treating a virus (e.g,. an RNA virus, such as a SARS-CoV-2) infection or a disease associated therewith (e.g., COVID-19) comprising administering Rigosertib or a composition thereof to a subject (e.g., a human subject). |
| FILED | Friday, May 28, 2021 |
| APPL NO | 17/927978 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/198 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230248706 | Zhao |
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| APPLICANT(S) | Ann And Robert H. Lurie Children's Hospital of Chicago (Chicago, Illinois) |
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| INVENTOR(S) | Youyang Zhao (Deerfield, Illinois) |
| ABSTRACT | Disclosed herein are methods and compositions for treatment of COVID-19 and associated sepsis, respiratory distress and organ failure, acute respiratory distress syndrome, sepsis, infection-induced organ failure, restenosis, critical limb ischemia, and vascular diseases associated with impaired endothelial regeneration, vascular repair, and vascular regeneration. In some embodiments, the methods include administering an effective amount of one or more of a) Dexamethasone, Resveratrol, N-acetylcysteine, Apocynin, Ebselen, APX-115, NOX2 inhibiting peptide, NOX2 inhibiting nucleic acid, Thienopyridine, orb) Selisistat, AG-1031, rabeprazole, phenazopyridine, roxadustat, molidustat, vadadustat, desidustat, decitabine, azacytidine, and analogues thereof, FOXM1 expressing nucleic acid, HIF1A expressing nucleic acid, SIRT1 inhibiting nucleic acid, EGLN1 inhibiting nucleic acid, or c) combination of one of a with one of b to a subject in need thereof. In some embodiments, the monotherapy or combination therapy is particularly useful for treatment of an elderly subject, and is useful to treat a subject at any age. |
| FILED | Thursday, June 24, 2021 |
| APPL NO | 18/002940 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5153 (20130101) A61K 31/472 (20130101) A61K 31/655 (20130101) A61K 31/4418 (20130101) A61K 31/4439 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230248721 | Auguste et al. |
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| APPLICANT(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Debra Auguste (Briarcliff Manor, New York); Marsha A. Moses (Brookline, Massachusetts); Peng Guo (Natick, Massachusetts) |
| ABSTRACT | A method of detecting triple negative breast cancer (TNBC) is provided. Overexpression of ICAM-1 is linked to an increased risk of TNBC. A composition of matter is also provided that binds an anti-ICAM~1 antibody to a nanoparticle. The composition may be used as an imaging agent and/or a therapeutic targeting agent. A therapeutically active molecule may be bound to the composition to provide targeted therapy. |
| FILED | Thursday, December 29, 2022 |
| APPL NO | 18/091145 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) A61K 31/191 (20130101) A61K 31/429 (20130101) A61K 31/4365 (20130101) A61K 31/4965 (20130101) Original (OR) Class A61K 47/555 (20170801) A61K 2121/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57415 (20130101) G01N 2333/70525 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230248733 | Strum et al. |
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| APPLICANT(S) | G1 Therapeutics, Inc. (Research Triangle Park, North Carolina) |
| ASSIGNEE(S) | G1 Therapeutics, Inc. (Research Triangle Park, North Carolina) |
| INVENTOR(S) | Jay Copeland Strum (Hillsborough, North Carolina); John Emerson Bisi (Apex, North Carolina); Patrick Joseph Roberts (Durham, North Carolina); Francis Xavier Tavares (Durham, North Carolina) |
| ABSTRACT | This invention is in the area of improved compounds and methods for treating selected cancers and hyperproliferative disorders. |
| FILED | Wednesday, August 17, 2022 |
| APPL NO | 17/890130 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/527 (20130101) Original (OR) Class A61K 31/529 (20130101) A61K 31/5377 (20130101) A61K 47/545 (20170801) A61K 47/6803 (20170801) A61K 47/6867 (20170801) A61K 51/0459 (20130101) A61K 51/0468 (20130101) Heterocyclic Compounds C07D 487/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230248767 | DUNHAM et al. |
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| APPLICANT(S) | Hemanext Inc. (Lexington, Massachusetts) |
| ASSIGNEE(S) | Hemanext Inc. (Lexington, Massachusetts) |
| INVENTOR(S) | Andrew DUNHAM (Tower Lakes, Illinois); Tatsuro YOSHIDA (West Newton, Massachusetts); Samuel O. SOWEMIMO-COKER (Dix Hills, New York) |
| ABSTRACT | Methods for prevention and reversal of inflammation. |
| FILED | Friday, January 20, 2023 |
| APPL NO | 18/157652 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/14 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230248769 | Bae et al. |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
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| INVENTOR(S) | Jooeun Bae (West Roxbury, Massachusetts); Nikhil C. Munshi (Needham, Massachusetts); Kenneth C Anderson (Wellesley, Massachusetts) |
| ABSTRACT | This disclosure relates to immunogenic peptides that are specific to B-cell maturation antigen (BCMA) and Transmembrane activator and CAML interactor (TACI), and methods of use thereof. |
| FILED | Monday, October 31, 2022 |
| APPL NO | 18/051492 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/193 (20130101) A61K 38/212 (20130101) A61K 38/217 (20130101) A61K 39/39 (20130101) A61K 39/3955 (20130101) A61K 2039/55544 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 7/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230248800 | Jiang et al. |
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| APPLICANT(S) | PharmaIN Corporation (Bothell, Washington) |
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| INVENTOR(S) | Han Jiang (Burlingame, California); Yao Yao (Seattle, Washington); Gerardo M. Castillo (Bothell, Washington); Akiko Nishimoto-Ashfield (Seattle, Washington); Christian Ventocilla (San Francisco, California); Elijah Bolotin (Bothell, Washington) |
| ABSTRACT | The present disclosure provides novel V1a partial agonists for partially activating a V1a receptor. The partial V1a agonist has a therapeutic index of at least 20 (e.g., at least 30, at least 40, at least 50, at least 60, at least 70, at least 80, at least 90, at least 100). Also provided are method of treating liver fibrosis, cirrhosis, portal hypertension, ascites, esophageal varices, fundal varices, bleeding, arterial hypotension, and/or hepatorenal syndrome, including administering to a subject in need thereof a therapeutically effective dose of a composition including the V1a partial agonist(s) of the present disclosure, optionally in combination with a V2 antagonist. |
| FILED | Friday, July 16, 2021 |
| APPL NO | 18/013389 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) A61K 38/08 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/10 (20180101) A61P 9/12 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230248805 | Sullenger et al. |
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| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
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| INVENTOR(S) | Bruce A. Sullenger (Durham, North Carolina); Jaewoo Lee (Durham, North Carolina) |
| ABSTRACT | The present invention relates, in general, to pattern-recognition receptors (PRRs), including toll-like receptors (TLRs), and, in particular, to a method of inhibiting nucleic acid-induced activation of, for example, endosomal TLRs using an agent that binds to the nucleic acid (“nucleic acid binding agent”), preferably, in a manner that is independent of the nucleotide sequence, the chemistry (e.g., DNA or RNA, with or without base or sugar modifications) and/or the structure (e.g., double-stranded or single-stranded, complexed or uncomplexed with, for example protein) of the nucleic acid(s) responsible for inducing TLR activation. The invention also relates to methods of identifying nucleic acid binding agents suitable for use in such methods. |
| FILED | Thursday, March 30, 2023 |
| APPL NO | 18/128957 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/13 (20130101) A61K 31/70 (20130101) A61K 31/722 (20130101) A61K 31/785 (20130101) A61K 38/16 (20130101) Original (OR) Class A61K 38/1709 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230248812 | Strober et al. |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
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| INVENTOR(S) | Samuel Strober (Stanford, California); Alexander Filatenkov (Menlo Park, California) |
| ABSTRACT | In one aspect, the present invention provides a method for treating cancer comprising tumor cell vaccination in combination with hematopoietic and immune cell transplantation. In some embodiments, the method involves autologous tumor cell vaccination prior to autologous hematopoietic and immune cell transplantation. In another aspect, the present invention provides a method of purifying tumor cells from a subject in preparation for vaccination. |
| FILED | Friday, April 07, 2023 |
| APPL NO | 18/297451 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/14 (20130101) A61K 35/17 (20130101) A61K 39/0011 (20130101) Original (OR) Class A61K 41/00 (20130101) A61K 2039/80 (20180801) A61K 2039/5152 (20130101) A61K 2039/55522 (20130101) A61K 2039/55561 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230248814 | Wu et al. |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
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| INVENTOR(S) | Catherine Wu (Boston, Massachusetts); Steven Carr (Cambridge, Massachusetts); Susan Klaeger (Cambridge, Massachusetts); Derin Keskin (Boston, Massachusetts) |
| ABSTRACT | The subject matter disclosed herein is generally directed to epitopes that specifically bind to subject specific HLA class I molecules in MCC. The epitope identified is specific for MCC and is encoded for in the Merkel Cell Polyomavirus (MCPyV) large T antigen (MCPyV LT). |
| FILED | Tuesday, June 01, 2021 |
| APPL NO | 17/928649 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/5154 (20130101) Peptides C07K 14/7051 (20130101) C07K 16/084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230248818 | Pardi et al. |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
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| INVENTOR(S) | Norbert Pardi (Philadelphia, Pennsylvania); Drew Weissman (Wynnewood, Pennsylvania) |
| ABSTRACT | The present invention relates to compositions and methods for inducing an adaptive immune response against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a subject. In certain embodiments, the present invention provides a composition comprising a nucleoside-modified nucleic acid molecule encoding a SARS-CoV-2 antigen, adjuvant, or a combination thereof. For example, in certain embodiments, the composition comprises a vaccine comprising a nucleoside-modified nucleic acid molecule encoding a SARS-CoV-2 antigen, adjuvant, or a combination thereof. |
| FILED | Thursday, July 08, 2021 |
| APPL NO | 18/004494 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 39/215 (20130101) Original (OR) Class A61K 2039/53 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230248832 | Chung et al. |
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| APPLICANT(S) | Emory University (Atlanta, Georgia); Georgia State University Research Foundation, Inc. (Atlanta, Georgia) |
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| INVENTOR(S) | Leland W.K. Chung (Beverly Hills, California); Xiaojian Yang (Shannxi, China PRC); Jianjun Cheng (Champaign, Illinois); Rong Tong (Urbana, Illinois); Maged Henary (Lawrenceville, Georgia) |
| ABSTRACT | The present invention describes small molecule ligand-drug conjugates and methods of using the small molecule ligand-drug conjugates for targeted treatment of cancer in a patient in need thereof. Further described are methods of sterilizing circulating tumor cells and determining drug concentration in cancer tissue. |
| FILED | Friday, March 17, 2023 |
| APPL NO | 18/123236 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/545 (20170801) Original (OR) Class A61K 47/546 (20170801) A61K 49/0002 (20130101) A61K 49/0032 (20130101) A61K 49/0052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230248840 | Moynihan et al. |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
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| INVENTOR(S) | Kelly Dare Moynihan (Allston, Massachusetts); Rebecca Lynn Holden (Cambridge, Massachusetts); Darrell J. Irvine (Arlington, Massachusetts); Bradley Lether Pentelute (Cambridge, Massachusetts) |
| ABSTRACT | The present invention provides a conjugate comprising an albumin binding peptide and a cargo, compositions for directing cargos to the lymphatic system, and vaccines. The methods of the invention can be used to increase an immune response, or to treat cancer or an infectious disease. |
| FILED | Tuesday, April 18, 2023 |
| APPL NO | 18/302655 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/0011 (20130101) A61K 39/001192 (20180801) A61K 47/646 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/00 (20180101) A61P 35/00 (20180101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) C07K 14/76 (20130101) C07K 14/4748 (20130101) C07K 2319/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230248849 | PAGEL |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Mark D. PAGEL (Houston, Texas) |
| ABSTRACT | We disclose a composition, comprising a compound, comprising a melanin precursor that spontaneously synthesizes a melanin when in free form in vivo, and a peptide directly covalently bonded to or indirectly linked to the melanin precursor, wherein the direct covalent bond or indirect link of the peptide to the melanin precursor blocks spontaneous synthesis of the melanin in vivo in the absence of protease activity. We also disclose methods of tumor imaging, tumor detection, diagnosis, and treatment, including methods comprising administering, to a patient suffering from a tumor, the composition; and either surgically resecting the tumor or thermally ablating the tumor, wherein the surgical resection is guided at least in part by contrast imparted by, or the thermally ablating targets cells containing, the melanin, wherein the melanin is spontaneously synthesized in the tumor after administering the composition. |
| FILED | Monday, July 26, 2021 |
| APPL NO | 18/004827 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 49/0056 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230248850 | Dai et al. |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
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| INVENTOR(S) | Hongjie Dai (Cupertino, California); Ani Baghdasaryan (Redwood City, California); Feifei Wang (Redwood City, California) |
| ABSTRACT | Provided are gold molecular clusters functionalized with phosphorylcholine (PC) ligands. Also provided are compositions comprising the gold molecular clusters and methods of in vivo imaging of a tissue in a subject, the methods comprising administering a composition of the present disclosure to the subject, and performing NIR-I or NIR-II in vivo fluorescence imaging of the tissue. Also provided are kits comprising the gold molecular clusters and compositions of the present disclosure, as well as methods of synthesizing gold molecular clusters functionalized with PC ligands. |
| FILED | Friday, January 27, 2023 |
| APPL NO | 18/102623 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0065 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230249006 | Khuri-Yakub et al. |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University Office of the General Counsel (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Butrus T. Khuri-Yakub (Palo Alto, California); Kwan Kyu Park (Seoul, South Korea); Kamyar Firouzi (San Jose, California); Younghun Kim (Namyangju-si, South Korea) |
| ABSTRACT | Improved acoustic neurostimulation is provided using two or more acoustic transducers generating an acoustic interference pattern. In a first operating mode the transducers are driven at the same frequency. In a second operating mode the transducers are driven at different frequencies. The acoustic interference pattern is varied electronically by control of the driving frequencies. In addition, a method for neurostimulation excites two confocal ultrasound transducers using an excitation waveform signal that has a time-varying frequency within range containing a resonance frequency of the two transducers, thereby increasing resolution and allowing electronic scanning. |
| FILED | Friday, March 31, 2023 |
| APPL NO | 18/129680 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) Original (OR) Class A61N 2007/0026 (20130101) A61N 2007/0078 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230249441 | Singamaneni et al. |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Srikanth Singamaneni (St. Louis, Missouri); Jingyi Luan (St. Louis, Missouri); Jeremiah Morrissey (St. Louis, Missouri); Evan Kharasch (St. Louis, Missouri) |
| ABSTRACT | Fluorescence-based techniques are the cornerstone of modern biomedical optics with applications ranging from bioimaging at various scales (organelle to organism) to detection and quantification of a wide variety of biological species of interest. However, feeble fluorescence signal remains a persistent challenge in meeting the ever-increasing demand to image, detect and quantify biological species of low abundance. Disclosed herein are simple and universal methods based on a flexible and conformal elastomeric film adsorbed with plasmonic nanostructures, referred to as “plasmonic skin” or “plasmonic patch”, that provide large and uniform enhancement of fluorescence on a variety of surfaces, through an “add-on-top” process. The novel fluorescence enhancement approach presented here represents a disease-, biomarker-, and application-agnostic ubiquitously-applicable fundamental and enabling technology to improve the sensitivity of existing analytical methodologies in an easy-to-handle and cost-effective manner, without changing and/or minimally altering the original procedures of the existing techniques. |
| FILED | Friday, May 06, 2022 |
| APPL NO | 17/662293 |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 27/06 (20130101) Original (OR) Class B32B 2307/422 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250042 | Dai et al. |
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| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mingji Dai (West Lafayette, Indiana); Chengsen Cui (West Lafayette, Indiana); Zhongjian Cai (Suzhou, Jiangsu, China PRC); Alexander Adibekian (Palm City, Florida); Brendan Dwyer (Palm Beach Gardens, Florida) |
| ABSTRACT | The present disclosure provides the first asymmetric total synthesis and target identification of the curcusone natural products. The novel convergent synthesis is built upon a cheap and abundant chiral pool molecule (8) and features a thermal [3,3]-sigmatropic rearrangement and an FeCl3-promoted global hydrolysis/adol condensation cascade to rapidly construct the critical cycloheptadienone core. By performing chemoproteomics with the alkyne probe 37, we identified the previously “undruggable” oncogenic protein BRAT1 as a key cellular target of 1d. Furthermore, 1d inhibits BRAT1 in cancer cells, thereby reducing cancer cell migration, increasing susceptibility to DNA damage, and inducing chemosensitization to the approved drug etoposide. Compound 1d is the first known small-molecule inhibitor for BRAT1, a master regulator of the DDR and DNA repair. Composition matters and methods of uses are within the scope of this disclosure. |
| FILED | Monday, September 27, 2021 |
| APPL NO | 18/445087 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 45/63 (20130101) C07C 49/643 (20130101) Original (OR) Class C07C 229/12 (20130101) Heterocyclic Compounds C07D 265/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250054 | SHEN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); THE GEORGE WASHINGTON UNIVERSITY (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sida SHEN (Chicago, Illinois); Alejandro VILLAGRA (Falls Church, Virginia); Alan KOZIKOWSKI (Chicago, Illinois) |
| ABSTRACT | The present disclosure provides methods, pharmaceutical compositions, and kits comprising histone deacetylase (HD AC) inhibitors of formula I, or a pharmaceutically acceptable salt thereof, wherein R1, R2, L1, L2, m, n, p, X, Y, and Z are as defined in the specification, including methods of increasing the sensitivity of cancer cells to the cytotoxic effects of radiotherapy and/or chemotherapy in a subject. |
| FILED | Friday, June 25, 2021 |
| APPL NO | 18/002952 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/17 (20130101) A61K 31/69 (20130101) A61K 39/3955 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 275/40 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250084 | Flaherty et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Daniel Patrick Flaherty (West Lafayette, Indiana); Val Joseph Watts (West Lafayette, Indiana); Tiffany S. Dwyer (Lafayette, Indiana); Shrinidhi Annadka (Lafayette, Indiana) |
| ABSTRACT | The present invention relates to a method of treatment for chronic pain, opioid dependence, alcohol use disorder or autism using a class of pyrimidinone compounds, an adenylyl cyclase 1 (AC1) inhibitor. The invention described herein also pertains to pharmaceutical compositions and methods for treating diseases in mammals using those compounds disclosed herein. |
| FILED | Friday, March 17, 2023 |
| APPL NO | 18/123096 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Heterocyclic Compounds C07D 403/04 (20130101) Original (OR) Class C07D 405/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250085 | Natarajan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (LIncoln, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Amarnath Natarajan (Elkhorn, Nebraska) |
| ABSTRACT | Provided herein are compounds having a structure of formula (I) and methods of using the disclosed compounds to inhibit IKKβ activity. |
| FILED | Monday, April 17, 2023 |
| APPL NO | 18/301693 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) Heterocyclic Compounds C07D 403/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250089 | La Spada et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California); Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Albert La Spada (Irvine, California); Daruka Mahadevan (San Antonio, Texas) |
| ABSTRACT | The disclosure provides for small molecule inhibitors of the regulatory kinase MAP4K3, and methods of use thereof. |
| FILED | Thursday, February 09, 2023 |
| APPL NO | 18/108005 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Heterocyclic Compounds C07D 403/12 (20130101) Original (OR) Class C07D 413/12 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250098 | MAJUMDAR et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Health Sciences and Pharmacy in St. Louis (St. Louis, Missouri); Purdue Research Foundation (West Lafayette, Indiana); The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | University of Health Sciences and Pharmacy in St. Louis (St. Louis, Missouri); Purdue Research Foundation (West Lafayette, Indiana); The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Susruta MAJUMDAR (St. Louis, Missouri); Richard M. VAN RIJN (West Lafayette, Indiana); Soumen CHAKRABORTY (St. Louis, Missouri); Balazs VARGA (St. Louis, Missouri); Anna M. GUTRIDGE (West Lafayette, Indiana); Dalibor SAMES (New York, New York) |
| ABSTRACT | In some aspects, the present disclosure provides compounds of the formula: wherein the variables are as defined herein. In some embodiments, these compounds may be used to reduce the consumption of alcohol in a patient. These compounds may be used in treat or prevent alcoholism or an alcohol abuse disorder and show an improved pharmaceutical profile relative to other commonly used compounds. |
| FILED | Tuesday, October 04, 2022 |
| APPL NO | 17/938003 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/32 (20180101) Heterocyclic Compounds C07D 471/14 (20130101) Original (OR) Class C07D 471/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250134 | CAO et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington); NORTHWESTERN UNIVERSITY (Evanston, Illinois); WASHINGTON UNIVERSITY (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Longxing CAO (Seattle, Washington); Brian COVENTRY (Seattle, Washington); Inna GORESHNIK (Seattle, Washington); Lauren MILLER (Seattle, Washington); David BAKER (Seattle, Washington); Lisa KOZODOY (Seattle, Washington); John BOWEN (Seattle, Washington); Lauren CARTER (Seattle, Washington); James Brett CASE (Seattle, Washington); Michael DIAMOND (Seattle, Washington); Natasha EDMAN (Seattle, Washington); Andrew HUNT (Seattle, Washington); Michael Christopher JEWETT (Seattle, Washington); Cassandra Jean OGOHARA (Seattle, Washington); Young-jun PARK (Seattle, Washington); Rashmi RAVICHANDRAN (Seattle, Washington); Lance Joseph STEWART (Seattle, Washington); David VEESLER (Seattle, Washington); Bastian VOGELI (Seattle, Washington); Alexandra C. WALLS (Seattle, Washington); Kejia WU (Seattle, Washington); Scott BOYKEN (Seattle, Washington); George UEDA (Seattle, Washington) |
| ABSTRACT | Polypeptide inhibitors of SARS-COV-2 are disclosed comprising an amino acid sequence at least 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to the amino acid sequence selected from the group consisting of SEQ ID NOS: 1-17, 19-21, 23-34 and 100-101, and their use for treating and limiting development of SARS-COV-2 infection. |
| FILED | Tuesday, May 25, 2021 |
| APPL NO | 18/004545 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/001 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250135 | JONGENEELEN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | JANSSEN VACCINES and PREVENTION B.V. (Leiden, Netherlands) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mandy Antonia Catharina JONGENEELEN (Leiden, Netherlands); Tina RITSCHEL (Oegstgeest, Netherlands); Ferdinand Jacobus MILDER (Zwolle, Netherlands); Indigo KING (Seattle, Washington); Yifan SONG (Seattle, Washington); Johannes Petrus Maria LANGEDIJK (Amsterdam, Netherlands); Boerries BRANDENBURG (Utrecht, Netherlands) |
| ABSTRACT | Provided herein are group 2 influenza hemagglutinin stem polypeptides, nucleic acids encoding said polypeptides, vectors comprising said nucleic acid and pharmaceutical compositions comprising the same, as well as methods of their use, in particular in the prevention and/or treatment of influenza virus infections. |
| FILED | Thursday, September 03, 2020 |
| APPL NO | 17/753506 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/16 (20180101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 2319/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250139 | Linghu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Changyang Linghu (Cambridge, Massachusetts); Edward S. Boyden (Cambridge, Massachusetts) |
| ABSTRACT | The invention, in some aspects, includes compositions encoding expression-recording islands (XRIs), compositions comprising XRIs, and methods for using XRIs for intracellular molecular recording. |
| FILED | Tuesday, October 11, 2022 |
| APPL NO | 18/045624 |
| CURRENT CPC | Peptides C07K 14/245 (20130101) Original (OR) Class C07K 2319/24 (20130101) C07K 2319/735 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250157 | Bjorkman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California); City of Hope (Duarte, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pamela J. Bjorkman (Pasadena, California); Alexander A. Cohen (Pasadena, California); Chengcheng Fan (Pasadena, California); John C. Williams (Duarte, California); Miso Park (Duarte, California) |
| ABSTRACT | Disclosed herein include antibodies or fragments thereof having specificity to a sarbecovirus spike protein receptor binding domain. Also provided are compositions, methods, and kits for isolating and using said antibodies or fragments thereof for preventing or treating, for example a coronavirus infection. |
| FILED | Thursday, December 01, 2022 |
| APPL NO | 18/060814 |
| CURRENT CPC | Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/76 (20130101) C07K 2317/92 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250172 | BUTTE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Manish J. BUTTE (Los Angeles, California); Mohammad Mahdi HASANI-SADRABADI (Los Angeles, California); Fatemeh S. MAJEDI (Los Angeles, California) |
| ABSTRACT | An implantable or injectable scaffold comprising immunostimulatory compounds and a suppressor of regulatory T cell induction is provided for use in immunotherapy treatments, including the treatment of cancers and other tumors, in particular solid tumors including inoperable tumors, as well as for other applications of immune enhancement and/or suppression. |
| FILED | Tuesday, September 20, 2022 |
| APPL NO | 17/933817 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/246 (20130101) C07K 16/247 (20130101) C07K 16/248 (20130101) C07K 16/2809 (20130101) Original (OR) Class C07K 16/2818 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250196 | Herrmann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | City of Hope (Duarte, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andreas Herrmann (Pasadena, California); Hua Yu (Glendora, California) |
| ABSTRACT | Provided herein are cell penetrating conjugates. The conjugates include non-cell penetrating proteins connected through a phosphorothioate nucleic acid, wherein the phosphorothioate nucleic acid enhances intracellular delivery of the non-cell penetrating proteins. Also provided are methods and kits including the conjugates provided herein. |
| FILED | Tuesday, April 11, 2023 |
| APPL NO | 18/298933 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/14 (20130101) A61K 47/549 (20170801) A61K 47/6843 (20170801) A61K 47/6851 (20170801) A61K 47/6871 (20170801) A61K 47/6879 (20170801) A61K 47/6889 (20170801) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/00 (20130101) C07K 16/18 (20130101) C07K 16/30 (20130101) C07K 16/40 (20130101) C07K 16/468 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/31 (20130101) C07K 2317/40 (20130101) C07K 2317/77 (20130101) C07K 2317/622 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 2310/18 (20130101) C12N 2310/315 (20130101) C12N 2310/3513 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250212 | Hearon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California); The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Keith Hearon (Boston, Massachusetts); Landon D. Nash (Sunnyvale, California); Thomas Wilson (San Leandro, California); Duncan J. Maitland (College Station, Texas); Mark A. Wierzbicki (College Station, Texas) |
| ABSTRACT | An embodiment includes a platform shape memory polymer system. Such an embodiment exhibits a blend of tunable, high performance mechanical attributes in combination with advanced processing capabilities and good biocompatibility. A post-polymerization crosslinking synthetic approach is employed that combines polyurethane and thiol-ene synthetic processes. Other embodiments are described herein. |
| FILED | Friday, March 24, 2023 |
| APPL NO | 18/189277 |
| CURRENT CPC | Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2105/04 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/73 (20130101) C08G 18/675 (20130101) C08G 18/758 (20130101) C08G 18/3206 (20130101) Original (OR) Class C08G 18/3212 (20130101) C08G 18/6715 (20130101) Compositions of Macromolecular Compounds C08L 75/04 (20130101) C08L 75/16 (20130101) C08L 81/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250407 | Jones et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Peter L. Jones (Carson City, Nevada); Charis L. Himeda (Reno, Nevada); Takako Jones (Carson City, Nevada) |
| ABSTRACT | The disclosure relates to methods and compositions for regulating expression of DUX4. In some aspects, methods described by the disclosure are useful for treating a disease associated with aberrant DUX4 expression (e.g., facioscapulohumeral muscular dystrophy. FSHD). |
| FILED | Tuesday, December 13, 2022 |
| APPL NO | 18/065255 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 15/11 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) C12N 2750/14141 (20130101) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250422 | DUAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE CURATORS OF THE UNIVERSITY OF MISSOURI (Columbia, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | DONGSHENG DUAN (Columbia, Missouri); XIUFANG PAN (Columbia, Missouri); YONGPING YUE (Columbia, Missouri) |
| ABSTRACT | Disclosed are recombinant adeno-associated virus (rAAV) nucleic acid vectors comprising inverted terminal repeats (ITRs) free of 5′-cytosine-phosphate-guanine-3′ (CpG) motifs. Also disclosed are rAAV particles comprising the rAAV vectors, and to compositions and methods for delivering nucleic acids and/or for gene therapy. Further disclosed are compositions and methods for treating diseases with AAV gene therapy using the rAAV vector. |
| FILED | Wednesday, April 07, 2021 |
| APPL NO | 17/995763 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250423 | PORTEUS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); BOCO Silicon Valley, Inc. (Palo Alto, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew H. PORTEUS (Palo Alto, California); Eric J. KILDEBECK (Stanford, California); Daniel P. DEVER (Mountain View, California); Joseph T. CLARK (Philadelphia, Pennsylvania); Ann TSUKAMOTO (Stanford, California); Nobuko UCHIDA (Palo Alto, California) |
| ABSTRACT | The invention provides methods for generating a genetically modified human neural stem cell, genetically modified human neural stem cells, and pharmaceutical compositions comprising the genetically modified human neural stem cells. Also provided are associated kits. The invention also provides methods for preventing or treating a neurodegenerative disease or a neurological injury in a human subject using genetically modified human neural stem cells. |
| FILED | Tuesday, January 03, 2023 |
| APPL NO | 18/092911 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/30 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) Original (OR) Class C12N 15/113 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) C12N 2310/315 (20130101) C12N 2310/346 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250431 | Varga et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven M. Varga (Coralville, Iowa); Kevin L. Legge (North Liberty, Iowa) |
| ABSTRACT | Disclosed are compositions and methods for vaccinating susceptible individuals against infection by respiratory syncytial virus (RSV). The disclosed compositions include vaccine compositions comprising an effective amount of respiratory syncytial virus (RSV) F protein in a pre-fusion stabilized form and/or M protein incorporated into biodegradable polyanhydride polymer particles for inducing an immune response against RSV. The vaccine compositions also may include a suitable adjuvant. |
| FILED | Thursday, February 17, 2022 |
| APPL NO | 17/674683 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 31/713 (20130101) A61K 31/7105 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1136 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/321 (20130101) C12N 2320/30 (20130101) C12N 2320/31 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250433 | LEE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Rumi LEE (Houston, Texas); Ronald A DEPINHO (Houston, Texas) |
| ABSTRACT | The disclosure provides methods and compositions for treating subject having cancers with abnormal WNT signaling, such as APC-deficient cancers. Accordingly, aspects of the disclosure relate to methods for treating APC-deficient cancers comprising administering an inhibitor of TDO2 or of a cytokine activated by TDO2. Additional aspects relate to methods for identifying a cancer as being sensitive to TDO2 inhibition comprising detecting a deficiency in an APC gene and/or measuring an expression level of TDO2. |
| FILED | Friday, February 26, 2021 |
| APPL NO | 17/905124 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/496 (20130101) A61K 31/713 (20130101) A61K 31/4439 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250452 | Samulski |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard Jude Samulski (Hillsborough, North Carolina) |
| ABSTRACT | Disclosed herein are methods and compositions comprising an adeno-associated virus 2.5 (AAV2.5) capsid protein, comprising one or more amino acids substitutions, (e.g., which does not contain a substitution at the position corresponding to amino acid 267 of AAV2.5, or does not contain a serine at the position corresponding to amino acid 267 of AAV2.5) wherein the substitutions introduce a new glycan binding site into the AAV capsid protein. |
| FILED | Monday, March 20, 2023 |
| APPL NO | 18/186746 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/16 (20180101) A61P 31/18 (20180101) A61P 31/20 (20180101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2750/14122 (20130101) C12N 2750/14142 (20130101) C12N 2750/14143 (20130101) C12N 2750/14171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250470 | ZHANG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | David ZHANG (Houston, Texas); Kerou ZHANG (Houston, Texas); Ping SONG (Houston, Texas) |
| ABSTRACT | Provided herein are reagents and methods for comprehensively enriching potential variants within targeted regions, named Amplicon Comprehensive Enrichment (ACE). The sequence variants enriched can include single nucleotide polymorphisms (SNPs), single nucleotide variants, or small insertions and deletions. Embodiments include procedures for integration with real-time polymerase chain reaction, next generation sequencing (NGS), and long-read sequencing. |
| FILED | Friday, June 25, 2021 |
| APPL NO | 18/003412 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6827 (20130101) C12Q 1/6844 (20130101) Original (OR) Class C12Q 1/6876 (20130101) C12Q 2600/16 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250481 | MELLER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MOREHOUSE SCHOOL OF MEDICINE (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert MELLER (Covington, Georgia); Roger P. SIMON (Atlanta, Georgia) |
| ABSTRACT | A method of distinguishing a subject with pre-clinical Alzheimer's disease from those with similar symptoms but other forms of dementia such as mild cognitive impairment. The blood RNA whole transcriptome profile of a subject with suspected pre-clinical Alzheimer's disease is obtained and analyzed against a reference blood RNA whole transcriptome profile from a subject with another form of dementia such as frontal temporal dementia, CADASIL or mild cognitive impairment (MCI). The blood RNA whole transcriptome profile includes the presence and quantitation of ncRNA. Methods to enhance treatment of epileptic seizures are also discussed. |
| FILED | Friday, January 27, 2023 |
| APPL NO | 18/160373 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6809 (20130101) C12Q 1/6869 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/166 (20130101) C12Q 2600/178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250483 | Kinde et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Isaac Kinde (Beaumont, California); Kenneth W. Kinzler (Frankford, Delaware); Bert Vogelstein (Baltimore, Maryland); Nickolas Papadopoulos (Towson, Maryland); Luis Diaz (Ellicott City, Maryland); Chetan Bettegowda (Lutherville, Maryland); Yuxuan Wang (Baltimore, Maryland) |
| ABSTRACT | The recently developed liquid-based Papanicolaou (Pap) smear allows not only cytologic evaluation but also collection of DNA for detection of HPV, the causative agent of cervical cancer. We tested these samples to detect somatic mutations present in rare tumor cells that might accumulate in the cervix once shed from endometrial and ovarian cancers. A panel of commonly mutated genes in endometrial and ovarian cancers was assembled and used to identify mutations in all 46 endometrial or cervical cancer tissue samples. We were able also able to identify the same mutations in the DNA from liquid Pap smears in 100% of endometrial cancers (24 of 24) and in 41% of ovarian cancers (9 of 22). We developed a sequence-based method to query mutations in 12 genes in a single liquid Pap smear without prior knowledge of the tumor's genotype. |
| FILED | Friday, October 28, 2022 |
| APPL NO | 18/050809 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6851 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/154 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57442 (20130101) G01N 33/57449 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250484 | Perou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Washington University (St. Louis, Missouri); University of Utah Research Foundation (Salt Lake City, Utah); British Columbia Cancer Agency Branch (Vancouver, Canada) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Charles M. Perou (Carrboro, North Carolina); Joel S. Parker (Apex, North Carolina); James Stephen Marron (Durham, North Carolina); Andrew Nobel (Chapel Hill, North Carolina); Philip S. Bernard (Salt Lake City, Utah); Matthew J. Ellis (St. Louis, Missouri); Elaine Mardis (Troy, Illinois); Torsten O. Nielson (Vancouver, Canada); Maggie Chon U. Cheang (Vancouver, Canada) |
| ABSTRACT | Methods for classifying and for evaluating the prognosis of a subject having breast cancer are provided. The methods include prediction of breast cancer subtype using a supervised algorithm trained to stratify subjects on the basis of breast cancer intrinsic subtype. The prediction model is based on the gene expression profile of the intrinsic genes listed in Table 1. This prediction model can be used to accurately predict the intrinsic subtype of a subject diagnosed with or suspected of having breast cancer. Further provided are compositions and methods for predicting outcome or response to therapy of a subject diagnosed with or suspected of having breast cancer. These methods are useful for guiding or determining treatment options for a subject afflicted with breast cancer. Methods of the invention further include means for evaluating gene expression profiles, including microarrays and quantitative polymerase chain reaction assays, as well as kits comprising reagents for practicing the methods of the invention. |
| FILED | Monday, January 23, 2023 |
| APPL NO | 18/158396 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/00 (20190201) G16B 25/10 (20190201) G16B 40/00 (20190201) G16B 40/20 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250485 | Kurtz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | David M. Kurtz (San Carlos, California); Maximilian Diehn (San Carlos, California); Arash Ash Alizadeh (San Mateo, California) |
| ABSTRACT | Processes and materials to detect cancer from a biopsy are described. In some cases, cell-free nucleic acids can be sequenced, and the sequencing result can be utilized to detect sequences derived from a neoplasm. Detection of somatic variants occurring in phase can indicate the presence of cancer in a diagnostic scan and a clinical intervention can be performed. |
| FILED | Friday, February 10, 2023 |
| APPL NO | 18/167803 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1089 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/7028 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) G16B 20/10 (20190201) G16B 20/20 (20190201) G16B 30/00 (20190201) G16B 30/10 (20190201) G16B 35/20 (20190201) G16B 40/00 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/40 (20180101) G16H 10/60 (20180101) G16H 20/10 (20180101) G16H 50/20 (20180101) G16H 50/30 (20180101) G16H 50/70 (20180101) G16H 70/60 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250539 | Sevov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christo Sevov (Columbus, Ohio); Taylor Hamby (Columbus, Ohio) |
| ABSTRACT | Disclosed herein are systems and methods for the electrochemical reductive cross-coupling of sp2 and sp3 hybridized carbon atoms. The methods proceed under mild conditions and have a wide substrate tolerance. |
| FILED | Thursday, February 09, 2023 |
| APPL NO | 18/166604 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/05 (20210101) Original (OR) Class C25B 3/09 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230251182 | Haghgooie et al. |
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| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ramin Haghgooie (Arlington, Arkansas); Kenneth T. Kotz (Auburndale, Massachusetts); Robert Granier (Boston, Massachusetts); Anne Celia Petrofsky (Sudbury, Massachusetts) |
| ABSTRACT | Reusable network of spatially-multiplexed microfluidic channels each including an inlet, an outlet, and a cuvette in-between. Individual channels may operationally share a main or common output channel defining the network output and optionally leading to a disposable storage volume. Alternatively, multiple channels are structured to individually lead to the storage volume. An individual cuvette is dimensioned to substantially prevent the formation of air-bubbles during the fluid sample flow through the cuvette and, therefore, to be fully filled and fully emptied. The overall channel network is configured to spatially lock the fluidic sample by pressing such sample with a second fluid against a closed to substantially immobilize it to prevent drifting due to the change in ambient conditions during the measurement. Thereafter, the fluidic sample is flushed through the now-opened valve with continually-applied pressure of the second fluid. System and method for photometric measurements of multiple fluid samples employing such network of channels. |
| FILED | Wednesday, April 19, 2023 |
| APPL NO | 18/303073 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 3/502723 (20130101) B01L 2200/143 (20130101) B01L 2200/146 (20130101) B01L 2300/0851 (20130101) B01L 2300/0858 (20130101) B01L 2300/0877 (20130101) B01L 2400/0622 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/03 (20130101) Original (OR) Class G01N 21/11 (20130101) G01N 21/253 (20130101) G01N 2021/0346 (20130101) G01N 2021/0357 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230251194 | NOLAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SCINTILLON INSTITUTE FOR BIOMEDICAL AND BIOENERGY RESEARCH (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John P. NOLAN (La Jolla, California); Erika DUGGAN (San Diego, California) |
| ABSTRACT | This technology relates in part to optical methods for analyzing particles, including nanoparticles, thereby determining their presence, identity, origin, size and/or number in a sample of interest. |
| FILED | Tuesday, September 06, 2022 |
| APPL NO | 17/903888 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/06 (20130101) G01N 15/1429 (20130101) G01N 15/1459 (20130101) G01N 21/6428 (20130101) Original (OR) Class G01N 33/542 (20130101) G01N 33/582 (20130101) G01N 33/5308 (20130101) G01N 33/56983 (20130101) G01N 2015/0065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230251195 | Adams et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicholas M. Adams (Nashville, Tennessee); Frederick R. HASELTON (Nashville, Tennessee); Zackary A. ZIMMERS (Nashville, Tennessee) |
| ABSTRACT | The number of unique testable conditions that can be detected in parallel from a sample in a PCR assay can be increased without need for larger sample volumes or additional expensive instruments. At least two fluorescent compounds, each designed to have a peak fluorescence excitation and/or emission within a common spectral channel, can be added to a sample in a tube, wherein each of the at least two fluorescent compounds is used to test for a unique testable condition. PCR assay can be performed on the contents of the tube. Then a spectral channel signal of each of the at least two fluorescent compounds can be determined based on fluorescence emission measurements and at least two properties of each of the at least two fluorescent compounds, wherein the spectral channel signals are analyzed to indicate a presence or absence of each of the unique testable conditions. |
| FILED | Friday, February 03, 2023 |
| APPL NO | 18/164028 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6858 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) Original (OR) Class G01N 2021/6439 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230251220 | Larimer |
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| FUNDED BY |
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| APPLICANT(S) | United States Department of Energy (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Joshua T. Larimer (McMurray, Pennsylvania) |
| ABSTRACT | Disclosed is an apparatus and method for crack measurement, including the steps of placing a plurality of sense leads on a surface of an object, passing a current through the object, sensing a change in electric potential in the interior of the object, and forming a crack profile of the interior of the object based on the sensed change in electric potential. |
| FILED | Tuesday, February 07, 2023 |
| APPL NO | 18/106777 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/20 (20130101) Original (OR) Class G01N 27/041 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230251245 | Rhodes et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Katherine L. Rhodes (South Hadley, Massachusetts); Kenneth A. Barr (Chicago, Illinois); Yoav Gilad (Chicago, Illinois) |
| ABSTRACT | In aspects, the present disclosure provides methods of using multi-tissue organoids bodies including for analyzing the genome or transcriptome of a mammal, analyzing a cellular response to a treatment, determining an effect of a substance, or analyzing a cellular response to a treatment. |
| FILED | Friday, December 16, 2022 |
| APPL NO | 18/067192 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5082 (20130101) Original (OR) Class G01N 2570/00 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/30 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230251269 | Larman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Harry B. Larman (Baltimore, Maryland); Daniel Monaco (Baltimore, Maryland) |
| ABSTRACT | The present invention relates to the field of allergies. More specifically, the present invention provides compositions and methods useful for identifying anti-allergen antibodies in a patient sample using phage display. In one embodiment, a method for detecting the presence of an antibody against an allergen in subject includes the steps of (a) contacting a reaction sample comprising a display library with a biological sample comprising antibodies, wherein the display library includes a plurality of peptides derived from a plurality of allergens; and (b) detecting at least one antibody bound to at least one peptide expressed by the display library, thereby detecting an antibody against the at least one peptide in the biological sample. |
| FILED | Thursday, July 15, 2021 |
| APPL NO | 18/015684 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1037 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6844 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5436 (20130101) G01N 33/6854 (20130101) Original (OR) Class G01N 2800/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230251273 | DE RIVERO VACCARI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Miami (Miami, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Juan Pablo DE RIVERO VACCARI (Miami, Florida); Robert W. KEANE (Miami, Florida); W. Dalton DIETRICH (Miami, Florida); Helen BRAMLETT (Miami, Florida) |
| ABSTRACT | The present invention provides compositions and methods for detecting components of the inflammasome in a sample from a subject as markers for brain injuries such as multiple sclerosis, stroke or traumatic brain injury. Methods of using such inflammasome markers to determine prognosis, direct treatment and monitor response to treatment for the subject with a brain injury such as multiple sclerosis, stroke, mild cognitive impairment or traumatic brain injury are also described. |
| FILED | Tuesday, July 12, 2022 |
| APPL NO | 17/812058 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/136 (20130101) A61K 31/137 (20130101) A61K 31/225 (20130101) A61K 31/277 (20130101) A61K 38/02 (20130101) A61K 38/215 (20130101) A61K 39/3955 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) Original (OR) Class G01N 33/6896 (20130101) G01N 2333/54 (20130101) G01N 2333/545 (20130101) G01N 2333/96469 (20130101) G01N 2800/285 (20130101) G01N 2800/2871 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230251275 | Al Gharaibeh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Faris N. Al Gharaibeh (Cincinnati, Ohio); Hector R. Wong (Cincinnati, Ohio) |
| ABSTRACT | Methods and compositions disclosed herein generally relate to methods of identifying, validating, and measuring clinically relevant, quantifiable biomarkers of diagnostic and therapeutic responses for blood, vascular, cardiac, and respiratory tract dysfunction, particularly as those responses relate to sepsis and/or necrotizing enterocolitis in pediatric patients. In particular, the invention relates to identifying two or more biomarkers associated with septic shock in pediatric patients, obtaining a sample from a pediatric patient having at least one indication of sepsis and/or necrotizing enterocolitis, then quantifying from the sample an amount of two or more of said biomarkers, wherein the level of said biomarker correlates with a predicted outcome. |
| FILED | Tuesday, January 31, 2023 |
| APPL NO | 18/104055 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6869 (20130101) G01N 33/6893 (20130101) Original (OR) Class G01N 2800/26 (20130101) G01N 2800/52 (20130101) G01N 2800/56 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230251276 | WALLACH et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cognizance Biomarkers LLC (Miami, Florida) |
| ASSIGNEE(S) | Cognizance Biomarkers LLC (Miami, Florida) |
| INVENTOR(S) | Todd WALLACH (Miami, Florida); Peter CRINO (Miami, Florida); John POLLARD (Miami, Florida); Elizabeth BRAND (Miami, Florida); Maura STRAUMAN (Miami, Florida); Christopher HOLLENBEAK (Miami, Florida); Richard ST. CLAIR (Miami, Florida); Jeffrey BOTBYL (Miami, Florida); John GLEDHILL (Miami, Florida) |
| ABSTRACT | Epileptic seizures are difficult to diagnose and are often difficult to distinguish from several conditions with similar presentations, and therefore, diagnosis of seizures is often a long, expensive, and unreliable process. This invention provides biomarkers for identifying seizures and epilepsy, assays for measuring and assessing biomarker concentration, predictive models based on biomarkers and computer systems for detecting, assessing and diagnosing phasic and tonic changes associated with seizures and epilepsy in all clinical and healthcare settings. Diagnostic methods, kits and predictive models provided herein provide quantitative and/or qualitative assessment in order to allow patients to proceed immediately to diagnostic and/or treatment protocols, and assess therapeutic treatment effectiveness. |
| FILED | Monday, January 30, 2023 |
| APPL NO | 18/102852 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/20 (20130101) A61K 31/27 (20130101) A61K 31/53 (20130101) A61K 31/55 (20130101) A61K 31/195 (20130101) A61K 31/513 (20130101) A61K 31/515 (20130101) A61K 31/551 (20130101) A61K 31/4015 (20130101) A61K 31/4166 (20130101) A61K 31/5513 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) Original (OR) Class G01N 2800/2857 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230251340 | Harkins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kevin Harkins (Nashville, Tennessee); Mark D. Does (Nashville, Tennessee) |
| ABSTRACT | Accurate measurement of gradient waveform errors can often improve image quality in sequences with time varying readout and excitation waveforms. Self-encoding or offset-slice method sequences are commonly used to measure gradient waveforms. However, the self-encoding method requires a long scan time, while the offset-slice method is often low precision, requiring the thickness of the excited slice to be small compared to the maximal k-space encoded by the test waveform. This disclosure describes a novel hybrid of those methods, referred to as variable-prephasing (VP). Like the offset-slice method, VP uses the change in signal phase from offset-slices to calculate the gradient waveform. Similar to the self-encoding method, repeated acquisitions with a variable amplitude self-encoding gradient mitigates the signal loss due to phase wrapping, which, in-turn, allows thicker slices and greater SNR. |
| FILED | Friday, February 03, 2023 |
| APPL NO | 18/164362 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/56518 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230253066 | DeGrado et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | William F. DeGrado (San Francisco, California); Nicholas Polizzi (San Francisco, California) |
| ABSTRACT | Disclosed herein, inter alia, are methods and systems for optimizing protein ligand interactions. |
| FILED | Wednesday, July 21, 2021 |
| APPL NO | 18/015582 |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 15/30 (20190201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230254010 | Khodagholy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dion Khodagholy (Cresskill, New Jersey); Zifang Zhao (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dion Khodagholy (Cresskill, New Jersey); Zifang Zhao (New York, New York) |
| ABSTRACT | System for ionic communication in an electrolyte are provided, the systems including a transmitter; a first plurality of electrodes coupled to the transmitter and in contact with an electrolyte; a receiver; and a second plurality of electrodes coupled to the receiver and in contact with the electrolyte, wherein the transmitter is configured to transmit at least one signal to the receiver by manipulating ions in the electrolyte using the first plurality of electrodes. In some of these systems, the transmitter and the first plurality of electrodes are configured to be placed inside a body comprising the electrolyte. In some of these systems, the first plurality of electrodes consists of two electrodes. In some of these systems, the first plurality of electrodes includes at least three electrodes and the at least one signal is a plurality of signals. |
| FILED | Monday, February 06, 2023 |
| APPL NO | 18/106467 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0031 (20130101) Transmission H04B 5/0012 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20230248096 | WEITZ et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kennon Products, Inc. (Sheridan, Wyoming) |
| ASSIGNEE(S) | Kennon Products, Inc. (Sheridan, Wyoming) |
| INVENTOR(S) | Mark WEITZ (Sheridan, Wyoming); Justin WOOD (Sheridan, Wyoming); Zachary GREY (Sheridan, Wyoming); Brock SWECKARD (Sheridan, Wyoming); Thomas BUSHNELL (Sheridan, Wyoming); Dakotah GALI (Sheridan, Wyoming) |
| ABSTRACT | The present disclosure provides high tensile strength FCL seams, as well as methods for forming high tensile strength FCL seams by laser welding. The present disclosure also provides weldable FCL tabs for the reinforcement of both linear and curved sections of seams, as well as methods for reinforcing linear and curved sections of seams with weldable FCL tabs. |
| FILED | Wednesday, May 26, 2021 |
| APPL NO | 17/926884 |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 27/245 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230248307 | LYNCH et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jerome P. LYNCH (Ann Arbor, Michigan); Wentao WANG (Ann Arbor, Michigan) |
| ABSTRACT | A method and an osseointegrated prosthesis system having an osseointegrated prosthesis member are provided having a monitoring system operably coupled to the osseointegrated prosthesis member configured to quantitatively assess the osseointegration of the osseointegrated prosthesis member, a wave-generating element coupled to the osseointegrated prosthesis member and configured to output guided waves along the osseointegrated prosthesis member interrogating an interface between bone and the osseointegrated prosthesis member, and a sensing system configured to sense a condition of the interface between bone and the prosthesis. |
| FILED | Thursday, March 30, 2023 |
| APPL NO | 18/128647 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/4504 (20130101) A61B 5/4851 (20130101) Original (OR) Class A61B 5/6811 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/76 (20130101) A61F 2002/30784 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230248338 | SPRINGER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Michael SPRINGER (Cambridge, Massachusetts); Richard NOVAK (Cambridge, Massachusetts) |
| ABSTRACT | The technology described herein is directed to an anterior nares swab that is automation compatible. In one aspect, the swab comprises a cap, a threaded portion, a neck, and a sample collection head. The cap can be integrally and/or monolithically formed with any one or more of the threaded portion, the neck, and the sample collection head; or can be removably coupled to any one or more of the threaded portion, the neck, and the sample collection head. In additional aspects, described herein are kits comprising said swabs and methods of using said swabs. |
| FILED | Tuesday, July 13, 2021 |
| APPL NO | 18/005276 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 10/0051 (20130101) Original (OR) Class Chemical or Physical Laboratory Apparatus for General Use B01L 3/50825 (20130101) B01L 2300/042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230248544 | Langenfeld et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DEKA Products Limited Partnership (Manchester, New Hampshire) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher C. Langenfeld (Nashua, New Hampshire); Christopher O. Evans (Amherst, New Hampshire); Stanley B. Smith, III (Raymond, New Hampshire); Alexander H. Muller (Manchester, New Hampshire); John M. Kerwin (Manchester, New Hampshire); Thomas S. Schnellinger (North Andover, Massachusetts); G. Michael Guay (Greenville, New Hampshire); Dirk A. van der Merwe (Manchester, New Hampshire) |
| ABSTRACT | A prosthetic arm apparatus comprising a plurality of segments that provide a user of the prosthetic arm apparatus with substantially the same movement capability and function as a human arm. The segments are connectable to one another and connectable to a harness mount that may be adorned by the user. Each segment of the plurality of segments provides a portion of the movement capability, enabling the plurality of connected segments connected to the harness mount to provide substantially the same movement capability as that lacking in the user. |
| FILED | Tuesday, April 18, 2023 |
| APPL NO | 18/302282 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/54 (20130101) Original (OR) Class A61F 2/70 (20130101) A61F 2/78 (20130101) A61F 2/581 (20130101) A61F 2/582 (20130101) A61F 2/583 (20130101) A61F 2/585 (20130101) A61F 2/586 (20130101) A61F 2002/543 (20130101) A61F 2002/546 (20130101) A61F 2002/5069 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230248651 | DESIMONE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (CHAPEL HILL, North Carolina) |
| ASSIGNEE(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (CHAPEL HILL, North Carolina) |
| INVENTOR(S) | JOSEPH M. DESIMONE (CHAPEL HILL, North Carolina); JASON P. ROLLAND (BELMONT, Massachusetts); BENJAMIN W. MAYNOR (DURHAM, North Carolina); LARKEN E. EULISS (AUGOURA HILLS, California); GINGER DENISON ROTHROCK (DURHAM, North Carolina); ANSLEY E. DENNIS (AUGUSTA, Georgia); EDWARD T. SAMULSKI (CHAPEL HILL, North Carolina); R. JUDE SAMULSKI (CHAPEL HILL, North Carolina) |
| ABSTRACT | The presently disclosed subject matter describes the use of fluorinated elastomer-based materials, in particular perfluoropolyether (PFPE)-based materials, in high-resolution soft or imprint lithographic applications, such as micro- and nanoscale replica molding, and the first nano-contact molding of organic materials to generate high fidelity features using an elastomeric mold. Accordingly, the presently disclosed subject matter describes a method for producing free-standing, isolated nanostructures of any shape using soft or imprint lithography technique. |
| FILED | Friday, April 21, 2023 |
| APPL NO | 18/305051 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) Original (OR) Class A61K 9/0097 (20130101) A61K 9/5138 (20130101) A61K 9/5153 (20130101) A61K 9/5192 (20130101) A61K 47/34 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 99/0085 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 40/00 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) Organic electric solid-state devices H10K 71/13 (20230201) Technical Subjects Covered by Former US Classification Y10T 428/3154 (20150401) Y10T 428/24273 (20150115) Y10T 428/24479 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230249031 | Eder |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INCLUDEHEALTH, INC. (Mason, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James Ryan Eder (Columbus, Ohio) |
| ABSTRACT | Systems and methods for providing a customized exercise protocol to a computing device of a user. As the user performs the exercise protocol, one or more cameras of the computing device can track the user's movements. The user's movement are assessed to determine if proper form and technique is being used. |
| FILED | Thursday, April 13, 2023 |
| APPL NO | 18/134281 |
| CURRENT CPC | Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 24/0006 (20130101) A63B 24/0062 (20130101) Original (OR) Class A63B 24/0075 (20130101) A63B 2024/0068 (20130101) A63B 2024/0071 (20130101) A63B 2220/05 (20130101) A63B 2220/806 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230249147 | Maruyama |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Benji Maruyama (Yellow Springs, Ohio) |
| ABSTRACT | Methods and apparatuses for making nanomaterials are disclosed. The methods involve passing one or more source materials through a high pressure and high temperature chamber with an open throat, and then allowing the reactants to expand into a lower pressure, lower temperature zone. The source material is non-stoichiometric and fuel-rich so that excess un-combusted primary source material can form the nanomaterials. In some cases, the apparatus may be in the form of a modified rocket engine. The methods may be used to make various materials including: carbon nanotubes, boron nitride nanomaterials, titanium dioxide, and any materials that are currently produced by flame synthesis, including but not limited to electrocatalysts. The methods may also be used to make nanomaterials outside the Earth's atmosphere. The methods can include making, coating, or repairing structures in space, such as antennae. |
| FILED | Monday, January 09, 2023 |
| APPL NO | 18/094490 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 3/062 (20130101) Original (OR) Class B01J 2203/066 (20130101) B01J 2203/0655 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/162 (20170801) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 23/07 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/64 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20230249173 — PLATFORM FOR ROBOTIC MICRO-EXPERIMENTATION OF SOLUTION-PROCESSED MATERIALS AND DEVICES
| US 20230249173 | Amassian et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aram Amassian (Raleigh, North Carolina); Tonghui Wang (Raleigh, North Carolina); Jacob Mauthe (Morrisville, North Carolina) |
| ABSTRACT | The present subject matter relates to systems and methods for the formulation of inks from stock solutions in which a liquid handler is configured to draw samples from a plurality of solution components and mix the components together to create one or more ink formulations, and a dispensing robot is configured to transfer the one or more ink formulations to a common substrate to form one or more material samples or a coating element in communication with the liquid handler is configured to transfer the one or more ink formulations to a common substrate to form one or more material samples. A controller in communication with each of the liquid handler and the dispensing robot can be configured to coordinate the creation and transfer of the one or more ink formulations. In addition, the one or more material samples can be analyzed using one or more characterization instrument configured to characterize the material samples on the common substrate. |
| FILED | Monday, February 06, 2023 |
| APPL NO | 18/106287 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 2219/00689 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/0268 (20130101) B01L 3/0293 (20130101) Original (OR) Class B01L 3/5085 (20130101) B01L 13/02 (20190801) Manipulators; Chambers Provided With Manipulation Devices B25J 9/1669 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230249174 | Qing |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (SCOTTSDALE, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Quan Qing (Chandler, Arizona) |
| ABSTRACT | Disclosed are systems and methods for delivering and/or linking molecules, such as DNA, between tunable metal nanogaps and measuring electrical and/or optical properties. |
| FILED | Tuesday, July 06, 2021 |
| APPL NO | 18/004663 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) Original (OR) Class B01L 2300/16 (20130101) B01L 2300/0645 (20130101) B01L 2300/0861 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230249327 | Coulson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zachary Coulson (Oklahoma City, Oklahoma); Bradley Sullivan (Shawnee, Oklahoma) |
| ABSTRACT | A sound suppressing device for reducing the sound made when using a piece of equipment or tool is disclosed. The sound suppressing device includes: an outer shell, a window in the top of the outer shell, a filler inside the outer shell, and a containment seal for the filler. The sound suppressing device has an opening extending between its top and bottom that is sized and configured to fit around a portion of the body of the tool that will be adjacent the work piece when the tool is in use. |
| FILED | Thursday, December 01, 2022 |
| APPL NO | 18/072893 |
| CURRENT CPC | Percussive Tools B25D 9/04 (20130101) B25D 17/11 (20130101) Original (OR) Class B25D 2250/365 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230249789 | Ripplinger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battle Sight Technologies, LLC (Dayton, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicholas R. Ripplinger (Springboro, Ohio); Christopher J. Vogt (Cincinnati, Ohio) |
| ABSTRACT | An apparatus that facilitates search and rescue, for example, in open water. The apparatus comprises a substrate with a particular geometry and a perimeter. The apparatus further comprises a cover positioned atop the substrate with the cover also having a particular geometry and perimeter, which correspond to the geometry and perimeter of the substrate. An air-tight seal seals the substrate perimeter to the cover perimeter and creates a sealed internal region. A breakable vessel holding an activator is located in the sealed internal region, along with illuminable dyes that are also located in the sealed internal region. When the breakable vessel is broken, the activator reacts with the illuminable dyes and illuminates the illuminable dyes. |
| FILED | Friday, March 31, 2023 |
| APPL NO | 18/194031 |
| CURRENT CPC | Launching, Hauling-out, or Dry-docking of Vessels; Life-saving in Water; Equipment for Dwelling or Working Under Water; Means for Salvaging or Searching for Underwater Objects B63C 9/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230249809 | Dunn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LOCKHEED MARTIN CORPORATION (Bethesda, Maryland) |
| ASSIGNEE(S) | LOCKHEED MARTIN CORPORATION (Bethesda, Maryland) |
| INVENTOR(S) | Eric Dunn (Trumbull, Connecticut); Keith M. Schenone (Fairfield, Connecticut); Sven R. Lofstrom (Irving, Texas) |
| ABSTRACT | According to an aspect, a method of assembling a mandrel includes assembling a plurality of members via interlocking features arranged at opposing edges of each member of the plurality of members to form a compartment, the assembled members having a collective outer surface that conforms to an inner surface of the spar. A support member is inserted into the compartment formed radially inward from the assembled members, the support member making contact with a portion of each member of the plurality of members. |
| FILED | Monday, April 17, 2023 |
| APPL NO | 18/135253 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 33/485 (20130101) B29C 53/824 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 99/0028 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Aeroplanes; Helicopters B64C 27/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230249811 | Tobin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| INVENTOR(S) | Evan S. Tobin (Trumbull, Connecticut); Daniel George Schuster (Bethlehem, Connecticut); David N. Schmaling (Southbury, Connecticut); Evan Medrano (Stratford, Connecticut); Masruk Siddique (Stratford, Connecticut); Erik M. Byrne (Amherst, Massachusetts); James Orbon (New Haven, Connecticut) |
| ABSTRACT | A rotor blade retention assembly is configured to connect a rotor blade to a central hub comprising a hub arm coupled to and extending radially outward from a hub bowl. The hub arm includes a hub arm lug. The rotor blade retention assembly includes a tension-torsion strap with an inboard end and an outboard end, the inboard end including an inboard pin hole and the outboard end including an outboard pin hole. The rotor blade retention assembly further includes an inboard blade pin and an outboard blade pin. The inboard blade pin is configured to extend through the hub arm lug and the inboard pin hole and to couple the inboard end of the tension-torsion strap to the hub arm. The outboard blade pin is configured to extend through a blade lug of a rotor blade and the outboard pin hole and to couple the outboard end of the tension-torsion strap to the rotor blade. |
| FILED | Friday, February 04, 2022 |
| APPL NO | 17/665432 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/10 (20130101) B64C 27/35 (20130101) B64C 27/48 (20130101) Original (OR) Class B64C 27/327 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230249825 | Anderson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of The United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Anderson (Colorado Springs, Colorado); Grant Appel (O'Fallon, Illinois); Nathaniel Bowen (Columbus, Mississippi); Hugh Briggs (Colorado Springs, Colorado); Spencer Flint (Seattle, Washington); Seth Konig (Biloxi, Mississippi); Erin Leslie (Oklahoma City, Oklahoma) |
| ABSTRACT | A system for sending surveillance signals from a hostile environment to an operator. The system comprises an operably movable tractor for ground hauling a trailer and an independently operable drone. The trailer has an actuatable elevator for holding a stockpile of relay sensors and comprising a pair of co-acting elevator belts defining a chute therebetween. The elevator holds a stack of relay sensors for elevation to a pickup-position by the drone. Optionally a conveyor chute may replenish the stack of relay sensors in the elevator. |
| FILED | Monday, August 29, 2022 |
| APPL NO | 17/822868 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/208 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 9/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230249978 | Chaloux et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brian L. Chaloux (Alexandria, Virginia); James A. Ridenour (Arlington, Virginia); Albert Epshteyn (Potomac, Maryland) |
| ABSTRACT | A method of preparing borosulfate materials avoids the need for fuming sulfuric acid, also known as oleum. Instead, B(OH)3 present in solution in concentrated sulfuric acid at 5% to 15% by weight is reacted with a cation source at 100-250° C. under dynamic vacuum while in connection with a receiving vessel comprising a desiccant and separate from the reaction vessel, thereby causing formation of a borosulfate material in the reaction vessel while eliminated water is collected in the receiving vessel. |
| FILED | Friday, January 13, 2023 |
| APPL NO | 18/096602 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 35/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250126 | Medintz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Igor L. Medintz (Washington, District of Columbia); Joseph Melinger (Washington, District of Columbia); William B. Knowlton (Boise, Idaho); Bernard Yurke (Boise, Idaho); Kimihiro Susumu (Washington, District of Columbia); Sang Ho Lee (Washington, District of Columbia); Adam Meares (Fairfax, Virginia); Divita Mathur (Fairfax, Virginia); Olga A. Mass (Boise, Idaho); Jeunghoon Lee (Boise, Idaho); Ryan D. Pensack (Boise, Idaho) |
| ABSTRACT | New phosphoramidite Cy5 derivatives can be used in automated DNA synthesis, allowing the labeling of DNA sequences with a wider array of chromophores than are presently commercially available. In addition to varying dye hydrophobicity/hydrophilicity, the 5,5′-substituents (including hexyloxy, triethyleneglycol monomethyl ether, tert-butyl, and chloro groups) can modulate electron donating/withdrawing character while also tuning resulting absorption and emission properties. Modification of the Cy5 periphery enables the tuning of photophysical properties, such as absorption and emission maxima, fluorescence quantum yield, and fluorescence lifetime. |
| FILED | Friday, January 27, 2023 |
| APPL NO | 18/160925 |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250134 | CAO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington); NORTHWESTERN UNIVERSITY (Evanston, Illinois); WASHINGTON UNIVERSITY (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Longxing CAO (Seattle, Washington); Brian COVENTRY (Seattle, Washington); Inna GORESHNIK (Seattle, Washington); Lauren MILLER (Seattle, Washington); David BAKER (Seattle, Washington); Lisa KOZODOY (Seattle, Washington); John BOWEN (Seattle, Washington); Lauren CARTER (Seattle, Washington); James Brett CASE (Seattle, Washington); Michael DIAMOND (Seattle, Washington); Natasha EDMAN (Seattle, Washington); Andrew HUNT (Seattle, Washington); Michael Christopher JEWETT (Seattle, Washington); Cassandra Jean OGOHARA (Seattle, Washington); Young-jun PARK (Seattle, Washington); Rashmi RAVICHANDRAN (Seattle, Washington); Lance Joseph STEWART (Seattle, Washington); David VEESLER (Seattle, Washington); Bastian VOGELI (Seattle, Washington); Alexandra C. WALLS (Seattle, Washington); Kejia WU (Seattle, Washington); Scott BOYKEN (Seattle, Washington); George UEDA (Seattle, Washington) |
| ABSTRACT | Polypeptide inhibitors of SARS-COV-2 are disclosed comprising an amino acid sequence at least 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to the amino acid sequence selected from the group consisting of SEQ ID NOS: 1-17, 19-21, 23-34 and 100-101, and their use for treating and limiting development of SARS-COV-2 infection. |
| FILED | Tuesday, May 25, 2021 |
| APPL NO | 18/004545 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/001 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250139 | Linghu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Changyang Linghu (Cambridge, Massachusetts); Edward S. Boyden (Cambridge, Massachusetts) |
| ABSTRACT | The invention, in some aspects, includes compositions encoding expression-recording islands (XRIs), compositions comprising XRIs, and methods for using XRIs for intracellular molecular recording. |
| FILED | Tuesday, October 11, 2022 |
| APPL NO | 18/045624 |
| CURRENT CPC | Peptides C07K 14/245 (20130101) Original (OR) Class C07K 2319/24 (20130101) C07K 2319/735 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250274 | Pollum, JR. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio) |
| ASSIGNEE(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Marvin Michael Pollum, JR. (Pittsburgh, Pennsylvania); Joseph Peter Kriley (Valencia, Pennsylvania); Masayuki Nakajima (Wexford, Pennsylvania); Ljiljana Maksimovic (Allison Park, Pennsylvania); Brian Kirk Rearick (Allison Park, Pennsylvania); Adam B. Powell (Wexford, Pennsylvania); David Joseph Fortman (Pittsburgh, Pennsylvania); Loubna Pagnotti (Wexford, Pennsylvania) |
| ABSTRACT | Disclosed herein is a composition comprising: an epoxy-containing component, elastomeric particles in an amount of greater than 11% by weight to 25% by weight based on total weight of the composition; and a curing component activatable by an external energy source, the curing component comprising at least one guanidine having a D90 particle size of 25 μm measured by dynamic light scattering. Also disclosed is the composition in an at least partially cured state. Also disclosed is a method for treating a substrate comprising applying the composition to a surface of a substrate; and applying an external energy source to cure the composition. Also disclosed are substrates comprising the composition. Also disclosed are substrates formed by the method of the present invention. |
| FILED | Monday, March 27, 2023 |
| APPL NO | 18/190798 |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 27/38 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 59/68 (20130101) C08G 59/226 (20130101) C08G 59/245 (20130101) C08G 59/4021 (20130101) C08G 2150/00 (20130101) C08G 2170/00 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/013 (20180101) C08K 2201/019 (20130101) Compositions of Macromolecular Compounds C08L 25/10 (20130101) C08L 63/04 (20130101) Original (OR) Class C08L 83/04 (20130101) C08L 2205/18 (20130101) C08L 2207/53 (20130101) C08L 2312/06 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 163/00 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 163/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250422 | DUAN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE CURATORS OF THE UNIVERSITY OF MISSOURI (Columbia, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | DONGSHENG DUAN (Columbia, Missouri); XIUFANG PAN (Columbia, Missouri); YONGPING YUE (Columbia, Missouri) |
| ABSTRACT | Disclosed are recombinant adeno-associated virus (rAAV) nucleic acid vectors comprising inverted terminal repeats (ITRs) free of 5′-cytosine-phosphate-guanine-3′ (CpG) motifs. Also disclosed are rAAV particles comprising the rAAV vectors, and to compositions and methods for delivering nucleic acids and/or for gene therapy. Further disclosed are compositions and methods for treating diseases with AAV gene therapy using the rAAV vector. |
| FILED | Wednesday, April 07, 2021 |
| APPL NO | 17/995763 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250540 | Schroer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Govemment of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thorsten G. Schroer (Palmdale, California); Gregory E. LeCroy (Lancaster, California); Miguel Aguila (Palmdale, California); Mayra R. Rodriguez (Lancaster, California); Tyler J. Downard (Phelan, California); Brianna L. MacLeod (Lancaster, California) |
| ABSTRACT | A process for the microfluidic electrochemical synthesis of geminal dipseudohalide or halide-pseudohalide compounds comprising the steps of pumping a solution comprising a compound of Formula I into a microfluidic electrochemical reactor in the presence of a base, one of a halide or pseudohalide salt (MY), and a mediator; applying an electrical current through the microfluidic electrochemical reactor; and performing oxidative addition to create a geminal dipseudohalide or halide-pseudohalide compound of the general Formula II |
| FILED | Thursday, January 12, 2023 |
| APPL NO | 18/153683 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/11 (20210101) Original (OR) Class C25B 9/19 (20210101) C25B 11/091 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250602 | Hooper et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Naval Information Warfare Center Pacific (San Diego, California) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (San Diego, California) |
| INVENTOR(S) | Ralph David Hooper (Lemon Grove, California); Taylor Doolittle (San Diego, California); William Abbot Chambers (Jamul, California) |
| ABSTRACT | A dock shock absorption device includes a frame and one or more energy dissipative elements. The frame is attached to a dock with the frame enclosing a pylon. The one or more energy dissipative elements attach to the frame and are equal to or less than 1 inch from the pylon. |
| FILED | Wednesday, February 09, 2022 |
| APPL NO | 17/667737 |
| CURRENT CPC | Launching, Hauling-out, or Dry-docking of Vessels; Life-saving in Water; Equipment for Dwelling or Working Under Water; Means for Salvaging or Searching for Underwater Objects B63C 1/02 (20130101) Hydraulic Engineering E02B 3/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230251149 | Adelson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Edward Adelson (Winchester, Massachusetts); Sandra Liu (Cambridge, Massachusetts) |
| ABSTRACT | A retrographic sensor includes a flexible transparent structure, a transparent elastomeric pad, and an at least partially reflective layer. The flexible transparent structure may be configured to elastically deform between multiple configurations. At least one light source emits light into the transparent structure. The flexible transparent structure may include one or more markers that are illuminated by the at least one light source. The retrographic sensor may also include a photosensitive detector configured to image the flexible transparent structure and one or more markers. A processor may determine a configuration of the flexible transparent structure based at least in part on an image from the one or more markers. |
| FILED | Friday, February 04, 2022 |
| APPL NO | 17/665186 |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/24 (20130101) Original (OR) Class G01L 5/0061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230251235 | Pedigo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Aaron E. Pedigo (Bloomington, Indiana); Derek Lengacher (Odon, Indiana) |
| ABSTRACT | Provided is a method of breaking down an oxide formed on a tin whisker using a current-limited voltage. A circuit is formed on a region of interest with a pair of probes and a substrate. A first sweep breaks down the oxide formed on the tin whisker and includes a current limiting to prevent the whisker from fusing open. A second sweep is performed at lower voltages that will not produce sufficient current to fuse the whisker open. The electrical resistance of the tin whisker is measured after breaking down the oxide. The inventive method allows for direct measurement of the resistance of metallic whiskers, does not require extrapolation from ideal electrical properties of bulk materials, allows for testing resistance in a variety of environments, and allows for measurement of time dependent variables, such as how long it takes for the oxide to reform in various environments. |
| FILED | Tuesday, November 15, 2022 |
| APPL NO | 17/986938 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/04 (20130101) G01N 31/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230251238 | Rosenstein et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jacob K. Rosenstein (Providence, Rhode Island); Christopher Rose (Providence, Rhode Island) |
| ABSTRACT | A system includes an array of chemical, pressure, and temperature sensors, and a temporal airflow modulator configured to provide sniffed vapors in a temporally-modulated sequence through a plurality of different air paths across multiple sensor locations. |
| FILED | Friday, February 17, 2023 |
| APPL NO | 18/170849 |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0018 (20130101) B81B 2201/0264 (20130101) B81B 2201/0278 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/0075 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230251368 | Rogers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shawn Rogers (Johns Creek, Georgia); Marc M. Pos (Duvall, Washington); Darren Goshi (El Segundo, California); David C. Vacanti (Renton, Washington) |
| ABSTRACT | The disclosure describes techniques to scan a radio frequency antenna beam along one or more axes. For example, for a wide transmit beam oriented such that the long axis is in azimuth, this disclosure describes techniques to scan the transmit beam in elevation, in the direction of a short axis of the transmit beam. The radar receive aperture may be synchronized with transmit beam to scan the radar receive aperture using RF beamforming such that the elevation scan of the field of view of the radar receive aperture follows the elevation scan of the transmit beam. The radar receiver circuitry may also down-convert the received radar signals to an intermediate frequency (IF). The radar receiver circuitry may digitally form monopulse receive beams at IF within the processing circuitry of the receiver electronics and digitally scan the monopulse receive beams along the long axis of the field of view. |
| FILED | Friday, February 04, 2022 |
| APPL NO | 17/665479 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/032 (20130101) G01S 7/35 (20130101) G01S 13/426 (20130101) Original (OR) Class G01S 13/4409 (20130101) G01S 13/4463 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230251894 | Brewer |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tony Brewer (Plano, Texas) |
| ABSTRACT | Chiplet systems may include a memory controller that has programmable atomic units that execute programmable atomic transactions. These instructions are stored in one or more memory partitions of memory in the programmable atomic unit. Since the programmable atomic unit executes programmable atomic transactions that are customized for various processes, and since the programmable atomic unit is a physical resource shared by multiple processes, the processes need a way of both loading the programmable atomic unit memory with instructions and a method of calling those instructions. Disclosed are methods, systems, and devices for registering, calling, and virtualizing programmable atomic transactions. |
| FILED | Tuesday, October 20, 2020 |
| APPL NO | 17/074811 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/467 (20130101) Original (OR) Class G06F 9/3004 (20130101) G06F 15/7825 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230252297 | Chu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Linsong Chu (White Plains, New York); Pranita Sharad Dewan (White Plains, New York); Raghu Kiran Ganti (Elmsford, New York); Joshua M. Rosenkranz (Westchester, New York); Mudhakar Srivatsa (White Plains, New York) |
| ABSTRACT | Aspects of the present disclosure relate to annotating or tagging customer data. In some embodiments, the annotating can include summarizing touchpoints into k-hot encoding feature vectors, mapping the feature vectors onto an embedding layer, predicting a hierarchical data sequence using the embedding layer and the feature vectors, extracting the feature vectors that are most influential in predicting the embedding layer, and outputting the touchpoints associated with the most influential feature vectors. |
| FILED | Tuesday, April 18, 2023 |
| APPL NO | 18/302255 |
| CURRENT CPC | Electric Digital Data Processing G06F 16/282 (20190101) G06F 16/285 (20190101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230252308 | Roy |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Radhika Roy (Howell, New Jersey) |
| ABSTRACT | Various embodiments that pertain to artificial intelligence algorithms. A repository can retain a reusable common set of artificial intelligence algorithms. Different users can access this common set of artificial intelligence algorithms and employ individual artificial intelligence algorithms in programs as appropriately as they are developing different applications and/or products. Employment of these individual artificial intelligence algorithms can include, for example, tailoring parameters based on the desires of the individual user’s desires using the same common set of algorithms or individually or as a group as appropriate. |
| FILED | Monday, November 02, 2020 |
| APPL NO | 17/086853 |
| CURRENT CPC | Electric Digital Data Processing G06F 8/36 (20130101) G06F 21/6218 (20130101) Original (OR) Class G06F 2221/2113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230252913 | Aarabi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Shahram Aarabi (Seattle, Washington); Jason Germany (Seattle, Washington); Abhijith Shasheendra (Seattle, Washington); Ketan Sunil Mhetre (Seattle, Washington) |
| ABSTRACT | A thermally representative phantom mammalian manikin assembly is provided. The assembly can include a cover portion representative of mammalian tissue partially enclosing a thermal cavity having a thermally representative material therein. The cover portion can have an opening with a cap extending across the opening and configured to further enclose the thermal cavity. The cap can have an aperture extending therethrough to receive a device extending through the aperture and into the thermally representative material within the thermal cavity. The device can be a thermocouple configured to measure a temperature of the thermally representative material. In assemblies representing mammalian limbs, the assembly can further include a second thermal cavity representing an additional portion of the limb, e.g., thermally representative upper and lower leg cavities. |
| FILED | Friday, February 10, 2023 |
| APPL NO | 18/167629 |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 7/021 (20130101) G01K 13/10 (20130101) G01K 2213/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/32 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 23/34 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230253066 | DeGrado et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | William F. DeGrado (San Francisco, California); Nicholas Polizzi (San Francisco, California) |
| ABSTRACT | Disclosed herein, inter alia, are methods and systems for optimizing protein ligand interactions. |
| FILED | Wednesday, July 21, 2021 |
| APPL NO | 18/015582 |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 15/30 (20190201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230253290 | Burrell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Keith R. Burrell (Rancho Palos Verdes, California); Andrew J. Bristol (Brentwood, California); Rosalio S. Vidaurri (Los Angeles, California); Kevin A. Miyamoto (Camarillo, California) |
| ABSTRACT | An apparatus includes a thermal spreader configured to remove thermal energy from a device to be cooled. The thermal spreader includes a ringframe having an opening, where the opening is configured to provide access to the device through the ringframe. The thermal spreader also includes a pair of thermal straps configured to fit within the opening. The pair of thermal straps is configured to be bonded to the device and to be fastened to the ringframe in order to provide the thermal energy from the device to the ringframe. |
| FILED | Thursday, February 10, 2022 |
| APPL NO | 17/650599 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/4006 (20130101) Original (OR) Class H01L 25/0655 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230253431 | O'Masta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HRL LABORATORIES, LLC (Malibu, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark O'Masta (Malibu, California); Jacob Hundley (Thousand Oaks, California); Jensen Severance (Malibu, California); Brian Hempe (Malibu, California); Christopher Roper (Malibu, California) |
| ABSTRACT | An imaging sensor package including: an imaging sensor; and a patterned substrate coupled to a surface of the imaging sensor. The imaging sensor and the patterned substrate being curved. The patterned substrate having a petal-shaped patterned area having a first thickness and a base substrate having a second thickness, the first thickness being greater than the second thickness. |
| FILED | Wednesday, April 12, 2023 |
| APPL NO | 18/299550 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14632 (20130101) Original (OR) Class H01L 27/14687 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230253522 | Razeghi |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Manijeh Razeghi (Wilmette, Illinois) |
| ABSTRACT | Diffusion-based and ion implantation-based methods are provided for fabricating planar photodetectors. The methods may be used to fabricate planar photodetectors comprising type II superlattice absorber layers but without mesa structures. The fabricated planar photodetectors exhibit high quantum efficiencies, low dark current densities, and high specific detectivities as compared to photodetectors having mesa structures. |
| FILED | Friday, March 17, 2023 |
| APPL NO | 18/185507 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/101 (20130101) H01L 31/105 (20130101) H01L 31/1035 (20130101) H01L 31/1844 (20130101) Original (OR) Class H01L 31/03046 (20130101) H01L 31/035236 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230253545 | Tour et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | WILLIAM MARSH RICE UNIVERSITY (Houston, Texas) |
| INVENTOR(S) | James M. Tour (Houston, Texas); Rodrigo Villegas Salvatierra (Houston, Texas); Gladys Anahi Lopez Silva (Houston, Texas) |
| ABSTRACT | Anodes, cathodes, and separators for batteries (electrochemical energy storage devices). The anodes are Li metal anodes having lithiated carbon films (Li-MWCNT) (as dendrite suppressors and protective coatings for the Li metal anodes). The cathodes are sulfurized carbon cathodes. The separators are GNR-coated (or modified) separators. The invention includes each of these separately (as well as in combination both with each other and with other anodes, cathodes, and separators) and the methods of making each of these separately (and in combination). The invention further includes a battery that uses at least one of (a) the anode having a lithiated carbon film, (b) the sulfurized carbon cathode, and (c) the GNR-modified separator in the anode/cathode/separator arrangement. For instance, a full battery can include the sulfurized carbon cathode in combination with the Li-MWCNT anode or a full battery can include the sulfurized carbon cathode in combination with other anodes (such as a GCNT-Li anode). |
| FILED | Wednesday, March 08, 2023 |
| APPL NO | 18/118834 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/58 (20130101) H01M 4/133 (20130101) Original (OR) Class H01M 4/136 (20130101) H01M 4/0404 (20130101) H01M 4/0471 (20130101) H01M 4/583 (20130101) H01M 4/625 (20130101) H01M 10/0525 (20130101) H01M 50/451 (20210101) H01M 2004/028 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230253801 | Longley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert F. Longley (Oxford, Connecticut); John Chellgren (Norwalk, Connecticut); Christopher Patrick Sullivan (Monroe, Connecticut) |
| ABSTRACT | Systems and methods for power and data distribution on an aircraft. One embodiment provides an aircraft comprising a plurality of nodes, a power system controller, and an aircraft controller. Each node is connected to a plurality of LRUs, and each node includes a node controller. The power system controller is configured to control power distribution to each node. The aircraft controller is configured to transmit data to each node and to receive data from each node. The node controller includes an electronic processor and a memory. The node controller is configured to control power to the plurality of LRUs, receive first data from at least one LRU of the plurality of LRUs, and provide the first data to the aircraft controller. The node controller is further configured to receive second data from the aircraft controller and provide the second data to at least one LRU of the plurality of LRUs. |
| FILED | Thursday, February 10, 2022 |
| APPL NO | 17/668763 |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/24 (20130101) B64D 2221/00 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 4/00 (20130101) Original (OR) Class H02J 7/0068 (20130101) H02J 2310/44 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230254047 | BECK et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Kristin M BECK (Livermore, California); Marko CETINA (College Park, Maryland); Michael Lurie GOLDMAN (University Park, Maryland) |
| ABSTRACT | Aspects of the present disclosure describe techniques for controlling coherent crosstalk errors that occur in multi-channel acousto-optic modulators (AOMs) by applying cancellation tones to reduce or eliminate the crosstalk errors. For example, a method and systems are described that include applying a first radio frequency (RF) tone to generate a first acoustic wave in a first channel of the multi-channel AOM, wherein a portion of the first acoustic wave interacts with a second channel to cause a crosstalk effect, and applying a second RF tone to generate a second acoustic wave in the second channel, wherein the second acoustic wave reduces or eliminates the crosstalk effect caused by the portion of the first acoustic wave. |
| FILED | Friday, November 11, 2022 |
| APPL NO | 18/054829 |
| CURRENT CPC | Transmission H04B 10/70 (20130101) Original (OR) Class H04B 10/114 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230254050 | DON et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CCDC Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael L. DON (Baltimore, Maryland); Gonzalo R. Arce (Newark, Delaware) |
| ABSTRACT | A method and apparatus for measuring antenna radiation patterns comprising an array of test antennas coupled to at least one transmitter and an antenna under test located proximate to the array of test antennas. A compressive sensing processor is coupled to the antenna under test and the array of test antennas to control signals emitted and received by the antenna under test and the array of test antennas. The received signals comprise either amplitude only signals or amplitude and phase signals. The compressive sensing processor processes the received signals using compressive sensing to produce an antenna radiation pattern. |
| FILED | Friday, February 04, 2022 |
| APPL NO | 17/592603 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 29/0814 (20130101) Transmission H04B 17/12 (20150115) H04B 17/0085 (20130101) Original (OR) Class H04B 17/102 (20150115) H04B 17/391 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230254206 | Yeh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Edmund Meng Yeh (Newton, Massachusetts); Khashayar Kamran (Allston, Massachusetts) |
| ABSTRACT | A framework for joint computation, caching, and request forwarding in data-centric computing-based networks comprises a virtual control plane, which operates on request counters for computations and data, and an actual plane, which handles computation requests, data requests, data objects and computation results in the physical network. A throughput optimal policy, implemented in the virtual plane, provides a basis for adaptive and distributed computation, caching, and request forwarding in the actual plane. The framework provides superior performance in terms of request satisfaction delay as compared with several baseline policies over multiple network topologies. |
| FILED | Wednesday, April 19, 2023 |
| APPL NO | 18/302959 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/547 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 41/082 (20130101) Original (OR) Class H04L 67/10 (20130101) H04L 67/568 (20220501) H04L 69/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230254797 | Civerolo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States Government as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Civerolo (San Diego, California); Nicholas Lumsden (Escondido, California); Nicholas Johnson (San Diego, California); Christopher Lichtenberg (San Diego, California) |
| ABSTRACT | A secure data transmission system and method for targeting specific receiver locations. The secure data transmission system includes a time multiplexer, a time delay unit, a receiver tacker, and a plurality of transmitters. Additionally, the secure data transmission system may include a multiplexing sequence, a digital switch, a plurality of empty vectors, a range calculator, a delay estimator, and a plurality of stream time delays. The method for targeting specific receiver location includes receiving an input data stream, multiplexing the input data steam, receiving at least one instantaneous receiver locations, calculating a plurality of transmission ranges for each of the plurality of output data streams, calculating a plurality of time delays for each of the plurality of output data streams, delaying each of the plurality of output data streams according its calculated time delay, and transmitting each of the plurality of output data streams. |
| FILED | Friday, February 04, 2022 |
| APPL NO | 17/650029 |
| CURRENT CPC | Wireless Communication Networks H04W 56/005 (20130101) Original (OR) Class H04W 56/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230255047 | Zhao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Haonan Zhao (Ann Arbor, Michigan); Stephen R. FORREST (Ann Arbor, Michigan) |
| ABSTRACT | An OLED comprises a first electrode, an emissive layer positioned over the first electrode, a charge transport layer positioned over the emissive layer, and a second electrode positioned over the charge transport layer, wherein the charge transport layer is in direct contact with the second electrode, and wherein the charge transport layer has an index of refraction of at least 1.7. An OLED comprises a cavity formed between first and second metal electrodes, an organic light emitting element positioned within the cavity, and an efficiency enhancement layer positioned between the organic light emitting element and the second silver electrode, the efficiency enhancement layer having a refractive index of at least 1.7. |
| FILED | Friday, January 20, 2023 |
| APPL NO | 18/157308 |
| CURRENT CPC | Organic electric solid-state devices H10K 50/16 (20230201) Original (OR) Class H10K 50/82 (20230201) H10K 50/816 (20230201) H10K 2102/20 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230255121 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Weigang Wang (Tucson, Arizona); Pravin Khanal (Tucson, Arizona) |
| ABSTRACT | A magnetic memory cell can include a reference ferromagnetic layer; a barrier layer on the reference ferromagnetic layer; a multiple-interface free layer (MIFL) on the barrier layer; and a capping layer on the MIFL. The MIFL has at least three coupled sublayers, providing at least four interfaces for the MIFL. |
| FILED | Wednesday, February 09, 2022 |
| APPL NO | 17/667973 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/02 (20130101) H01L 43/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20230248878 | RADISCH et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Bio DG, Inc. (Poway, California); U.S. DEPARTMENT OF ENERGY (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Herbert RADISCH (San Diego, California); Paul JABLONSKI (Poway, California) |
| ABSTRACT | The invention provides medical devices comprising high-strength alloys which degrade over time in the body of a human or animal, at controlled degradation rates, without generating emboli and which have enhanced degradation due to the presence of a halogen component. In one embodiment the alloy is formed into a bone fixation device such as an anchor, screw, plate, support or rod. In another embodiment the alloy is formed into a tissue fastening device such as staple. In yet another embodiment, the alloy is formed into a dental implant or a stent. |
| FILED | Wednesday, September 14, 2022 |
| APPL NO | 17/944432 |
| CURRENT CPC | Dentistry; Apparatus or Methods for Oral or Dental Hygiene A61C 8/0012 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/042 (20130101) Original (OR) Class A61L 31/16 (20130101) A61L 31/022 (20130101) A61L 31/148 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/12292 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230249137 | FRAYNE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Via Separations, Inc. (Watertown, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen Hale FRAYNE (Watertown, Massachusetts); Lymaris ORTIZ RIVERA (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure relates to an alkylated graphene oxide membrane comprising a plurality of graphene oxide layers, each graphene oxide layer including at least one graphene oxide sheet covalently coupled to a chemical spacer, the chemical spacer being of Formula I: The present disclosure also relates to a filtration apparatus comprising an alkylated graphene oxide membrane disposed on a support substrate. |
| FILED | Thursday, March 02, 2023 |
| APPL NO | 18/116762 |
| CURRENT CPC | Separation B01D 67/0044 (20130101) B01D 67/0046 (20130101) B01D 67/0076 (20130101) B01D 69/02 (20130101) B01D 69/107 (20220801) B01D 69/1213 (20220801) B01D 69/1216 (20220801) B01D 71/024 (20130101) B01D 71/0211 (20220801) Original (OR) Class B01D 2323/36 (20130101) B01D 2323/081 (20220801) B01D 2323/219 (20220801) B01D 2325/06 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/205 (20130101) B01J 20/262 (20130101) B01J 20/324 (20130101) B01J 20/3085 (20130101) B01J 20/3212 (20130101) B01J 20/28007 (20130101) B01J 20/28035 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/194 (20170801) C01B 32/198 (20170801) C01B 2204/04 (20130101) Production of Cellulose by Removing Non-cellulose Substances From Cellulose-containing Materials; Regeneration of Pulping Liquors; Apparatus Therefor D21C 11/0042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230249149 | Even |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Dakota Even (Overland Park, Kansas) |
| ABSTRACT | Porous polysiloxane microspheres may be formed using a double emulsion (W/O/W) and double reaction process. The methods generally comprise forming a first emulsion and reacting components of the emulsion phases to form reinforced hydrogen gas pockets. The first emulsion is then combined with a solvent to form a second emulsion comprising a plurality of microspheres making up the dispersed phase. The microspheres comprise the reinforced gas pockets encapsulated by a polysiloxane, which are cured and recovered. The microspheres are particularly useful as fillers for low density composite materials and sensor applications. |
| FILED | Monday, February 07, 2022 |
| APPL NO | 17/665763 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/16 (20130101) Original (OR) Class Printing, Duplicating, Marking, or Copying Processes; Colour Printing, B41M 5/0023 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 77/08 (20130101) C08G 77/12 (20130101) C08G 77/20 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230249236 | SMITH et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Keystone Tower Systems, Inc. (DENVER, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eric D. SMITH (Boulder, Colorado); Rosalind K. TAKATA (Denver, Colorado); Alexander H. SLOCUM (Bow, New Hampshire); Samir A. NAYFEH (Shrewsbury, Massachusetts) |
| ABSTRACT | Feeding stock used to form a tapered structure into a curving device such that each point on the stock undergoes rotational motion about a peak location of the tapered structure; and the stock meets a predecessor portion of stock along one or more adjacent edges. |
| FILED | Monday, February 06, 2023 |
| APPL NO | 18/164826 |
| CURRENT CPC | Rolling of Metal B21B 39/02 (20130101) Original (OR) Class Manufacture of Metal Sheets, Wire, Rods, Tubes or Profiles, Otherwise Than by Rolling; Auxiliary Operations Used in Connection With Metal-working Without Essentially Removing Material B21C 37/124 (20130101) B21C 37/126 (20130101) B21C 37/185 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230249397 | JOSHIPURA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Ishan JOSHIPURA (Oakland, California); Martin DE BEER (Berkeley, California); Jordan Seiji LUM (Livermore, California); Maxim SHUSTEFF (Piedmont, California); David Matthew STOBBE (Livermore, California) |
| ABSTRACT | The present disclosure relates to an additive manufacturing system for forming at least one of forming a part or modifying a surface using a volume of polymerizable resin. The system makes use of a subsystem for generating power output signals, and at least one acoustic transducer. The acoustic transducer is placed in a vicinity of the volume of polymerizable resin and is responsive to the power output signals. The acoustic transducer generates and projects ultrasound energy in response to receiving the power output signals to at least one spatial location within the volume of resin to cause polymerization of at least a portion of the volume of resin to at least one of form the part or modify the surface. |
| FILED | Wednesday, February 09, 2022 |
| APPL NO | 17/668205 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/129 (20170801) Original (OR) Class B29C 64/268 (20170801) B29C 64/277 (20170801) B29C 64/393 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201) B33Y 70/10 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230249974 | Kidambi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); King Fahd University of Petroleum and Minerals (Dhahran, Saudi Arabia) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); King Fahd University of Petroleum and Minerals (Dhahran, Saudi Arabia) |
| INVENTOR(S) | Piran Kidambi (Somerville, Massachusetts); Ahmed Ibrahim (Dhahran, Saudi Arabia); Tahar Laoui (Dhahran, Saudi Arabia); Jing Kong (Winchester, Massachusetts); Rohit N Karnik (Cambridge, Massachusetts); Sui Zhang (Kent Vale, Singapore) |
| ABSTRACT | Atomically thin layers including pores, their method of manufacture, and their use are disclosed. In some embodiments, pores may be formed in an atomically thin layer by growing the atomically thin layer on exposed portions of a substrate that includes islands comprising a material that is different than the material of the substrate. In some embodiments, pores and/or defects may be formed in an atomically thin layer by employing growth conditions that promote the formation of defects and/or pores. In certain embodiments, pores and/or defects may be etched to enlarge their size. |
| FILED | Thursday, November 03, 2022 |
| APPL NO | 17/980413 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/186 (20170801) Original (OR) Class Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/26 (20130101) C23C 16/56 (20130101) C23C 16/0227 (20130101) C23C 16/0236 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250099 | Redline et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Erica M. Redline (Albuquerque, New Mexico); Chad L. Staiger (Albuquerque, New Mexico); David R. Wheeler (Albuquerque, New Mexico); Leah N. Appelhans (Tijeras, New Mexico); Jeffrey C. Foster (Albuquerque, NM, New Mexico) |
| ABSTRACT | Curatives and their resulting thermosets and other crosslinked polymers can reduce thermal expansion mismatch between an encapsulant and objects that are encapsulated. This can be accomplished by incorporating a negative CTE moiety into the thermoset resin or polymer backbone. The negative CTE moiety can be a thermal contractile unit that shrinks as a result of thermally induced conversion from a twist-boat to chair or cis/trans isomerization upon heating. Beyond CTE matching, other potential uses for these crosslinked polymers and thermosets include passive energy generation, energy absorption at high strain rates, mechanophores, actuators, and piezoelectric applications. |
| FILED | Monday, March 20, 2023 |
| APPL NO | 18/123665 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 13/547 (20130101) C07C 211/60 (20130101) C07C 2602/12 (20170501) C07C 2603/30 (20170501) C07C 2603/36 (20170501) Heterocyclic Compounds C07D 321/12 (20130101) C07D 471/14 (20130101) Original (OR) Class Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/17 (20130101) C08K 5/053 (20130101) C08K 5/235 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250111 | THOMPSON et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (LOS ANGELES, California) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (LOS ANGELES, California) |
| INVENTOR(S) | Mark E. THOMPSON (Anaheim Hills, California); Peter I. DJUROVICH (Long Beach, California); Rasha HAMZE (Los Angeles, California); Shuyang SHI (Los Angeles, California); Moon Chul JUNG (Los Angeles, California) |
| ABSTRACT | Provided is a compound having Formula I where rings A and B are independently a five-membered or six-membered, carbocyclic or heterocyclic ring, each of which is optionally aromatic; together with nitrogen atoms bonded to ring A and ring B, ring W is a 5-membered N-heterocyclic carbene; and the remaining variables are as defined herein. |
| FILED | Friday, March 31, 2023 |
| APPL NO | 18/193678 |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 1/08 (20130101) C07F 1/10 (20130101) Original (OR) Class C07F 1/12 (20130101) Organic electric solid-state devices H10K 50/11 (20230201) H10K 85/371 (20230201) H10K 2101/10 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250207 | Bae et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ORION POLYMER CORP. (Cohoes, New York) |
| ASSIGNEE(S) | ORION POLYMER CORP. (Cohoes, New York) |
| INVENTOR(S) | Chulsung Bae (Cohoes, New York); Gregory Kline (Kendallville, Indiana); Bharat Shrimant (State College, Pennsylvania); Ding Tian (Troy, New York); Xiaofeng Wang (Katy, Texas); Yu Seung Kim (White Rock, New Mexico); Eun Joo Park (Santa Fe, New Mexico); Santosh Adhikari (Los Almos, New Mexico) |
| ABSTRACT | Disclosed herein in various embodiments are aryl-ether free polyaromatic polymers based on random copolymer architecture with two, three, or more aromatic ring components and methods of preparing those polymers. The polymers of the present disclosure can be used as ion exchange membranes, e.g., as anion exchange membranes, and ionomer binders in alkaline electrochemical devices. |
| FILED | Monday, February 06, 2023 |
| APPL NO | 18/164980 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 41/14 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 232/06 (20130101) Original (OR) Class Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/17 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250212 | Hearon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California); The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Keith Hearon (Boston, Massachusetts); Landon D. Nash (Sunnyvale, California); Thomas Wilson (San Leandro, California); Duncan J. Maitland (College Station, Texas); Mark A. Wierzbicki (College Station, Texas) |
| ABSTRACT | An embodiment includes a platform shape memory polymer system. Such an embodiment exhibits a blend of tunable, high performance mechanical attributes in combination with advanced processing capabilities and good biocompatibility. A post-polymerization crosslinking synthetic approach is employed that combines polyurethane and thiol-ene synthetic processes. Other embodiments are described herein. |
| FILED | Friday, March 24, 2023 |
| APPL NO | 18/189277 |
| CURRENT CPC | Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2105/04 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/73 (20130101) C08G 18/675 (20130101) C08G 18/758 (20130101) C08G 18/3206 (20130101) Original (OR) Class C08G 18/3212 (20130101) C08G 18/6715 (20130101) Compositions of Macromolecular Compounds C08L 75/04 (20130101) C08L 75/16 (20130101) C08L 81/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250251 | ALLEN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert David ALLEN (Golden, Colorado); Nicholas A. RORRER (Golden, Colorado); Gregg Tyler BECKHAM (Golden, Colorado); Katrina Marie KNAUER (Denver, Colorado); Minjung LEE (Arvada, Colorado) |
| ABSTRACT | Described herein are systems and methods for the recycling of polymer materials that utilize recoverable solvents to efficiently produce high quality valuable polymer while removing contaminants such as metals, dyes or fibers present in the product to be recycled. The described methods may reduce temperature requirements, both reducing the energy requirements as well as providing higher quality recycled feedstocks by, for example, reducing discoloration due to high temperature processing. |
| FILED | Wednesday, February 08, 2023 |
| APPL NO | 18/166331 |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 11/02 (20130101) Original (OR) Class C08J 11/08 (20130101) C08J 2367/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250303 | Nguyen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Du Nguyen (Fremont, California); Eric Duoss (Dublin, California); Jeremy Lenhardt (Tracy, California); Thomas S. Wilson (San Leandro, California) |
| ABSTRACT | The silicone-based ink for additive manufacturing includes a siloxane macromer, and a porogen mixture comprising a water-soluble porogen and a surfactant. The product of additive manufacturing with a silicone-based ink includes a three-dimensional printed structure including a plurality of continuous filaments arranged in a predefined pattern and a plurality of inter-filament pores defined by the predefined pattern of the continuous filaments. In addition, each continuous filament of the three-dimensional printed structure includes a silicone matrix having an open cell structure with a plurality of intra-filament pores, and the intra-filament pores form continuous channels through the silicone matrix. |
| FILED | Friday, March 31, 2023 |
| APPL NO | 18/129716 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/118 (20170801) B29C 64/379 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2083/00 (20130101) B29K 2439/06 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 40/20 (20200101) B33Y 70/00 (20141201) B33Y 70/10 (20200101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/037 (20130101) C09D 11/102 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250504 | Monroe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | James Alan Monroe (Syracuse, New York); Ibrahim (nmn) Karaman (College Station, Texas); Raymundo (nmn) Arroyave (College Station, Texas) |
| ABSTRACT | A controlled thermal coefficient product manufacturing system and method is disclosed. The disclosed product relates to the manufacture of metallic material product (MMP) having a thermal expansion coefficient (TEC) in a predetermined range. The disclosed system and method provides for a first material deformation (FMD) of the MMP that comprises at least some of a first material phase (FMP) wherein the FMP comprises martensite randomly oriented and a first thermal expansion coefficient (FTC). In response to the FMD at least some of the FMP is oriented in at least one predetermined orientation. Subsequent to deformation, the MMP comprises a second thermal expansion coefficient (STC) that is within a predetermined range and wherein the thermal expansion of the MMP is in at least one predetermined direction. The MMP may be comprised of a second material phase (SMP) that may or may not transform to the FMP in response to the FMD. |
| FILED | Tuesday, April 18, 2023 |
| APPL NO | 18/135872 |
| CURRENT CPC | Working or Processing of Sheet Metal or Metal Tubes, Rods or Profiles Without Essentially Removing Material; Punching Metal B21D 22/20 (20130101) B21D 35/002 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/14 (20130101) B23K 26/38 (20130101) B23K 26/0643 (20130101) B23K 26/0648 (20130101) B23K 26/1476 (20130101) Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 1/785 (20130101) C21D 8/005 (20130101) C21D 9/0068 (20130101) Original (OR) Class Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/08 (20130101) C22F 1/10 (20130101) C22F 1/183 (20130101) Details or Accessories of Furnaces, Kilns, Ovens, or Retorts, in so Far as They Are of Kinds Occurring in More Than One Kind of Furnace F27D 7/06 (20130101) F27D 11/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250576 | Dai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sheng Dai (Knoxville, Tennessee); Prashant Bagri (Hillsboro, Oregon); Huimin Luo (Knoxville, Tennessee) |
| ABSTRACT | A method for converting amorphous carbon fiber to graphitized carbon fiber, the method comprising immersing the amorphous carbon fiber into a molten anhydrous alkaline earth salt (e.g., CaCl2) and/or MgCl2) maintained at a temperature within a range of 720° C.-920° C. or 780° C.-920° C. while the amorphous carbon fiber is cathodically polarized at a voltage within a range of −2.2V to −2.8V for a period of time (e.g., 0.5-6 hours) to result in conversion of the amorphous carbon fiber to the graphitized carbon fiber, wherein the graphitized carbon fiber is at least partially graphitized. |
| FILED | Thursday, February 09, 2023 |
| APPL NO | 18/107715 |
| CURRENT CPC | Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 10/06 (20130101) Original (OR) Class D06M 2101/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250877 | Eryilmaz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Uchicago Argonne, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | Uchicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Osman L. Eryilmaz (Plainfield, Illinois); Vanessa DaSilva (Countryside, Illinois); Ali Erdemir (Naperville, Illinois) |
| ABSTRACT | A sealing system having a seal engagable with a reciprocating component. The seal includes a catalytic additive that catalyzes the formation of a carbon tribolayer. The tribolayer provides for a lubricous environment while maintaining seal integrity and continued lubrication during active use (reciprocation). |
| FILED | Wednesday, February 08, 2023 |
| APPL NO | 18/107269 |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/04 (20130101) C08K 3/22 (20130101) C08K 2201/005 (20130101) Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition C10M 107/02 (20130101) C10M 2205/003 (20130101) Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions C10N 2040/34 (20130101) Pistons; Cylinders; Sealings F16J 15/162 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250989 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma); University of Miami (Miami, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gang Wang (Palmetto Bay, Florida); Li Song (Norman, Oklahoma); Zufen Wang (Miami, Florida); Rodney D. Hurt (Norman, Oklahoma) |
| ABSTRACT | The present disclosure describes a system comprising a gain-scheduling control strategy which improves its nonlinear control performance. A control-oriented model, which does not require numerous physical parameters and extensive test data, has been developed to address the nonlinearity of the fan system. Based on theoretical model and experimental verifications, the issue of an aggressive response with a conventional fixed-gain controller is caused by the fact that the system gain is proportional to the ratio of the duct static pressure to the fan speed. To address the issue, a scheduling function of the measurable duct static pressure and fan speed is included in the conventional fixed-gain controller to compensate for the fan system gain variation. The gain-scheduling control strategy approximately maintains the identical control performance under all operation conditions. The gain-scheduling control strategy can be readily implemented on a processor without intensive computation and additional measurements. |
| FILED | Tuesday, February 07, 2023 |
| APPL NO | 18/165686 |
| CURRENT CPC | Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 11/46 (20180101) F24F 11/63 (20180101) F24F 11/77 (20180101) Original (OR) Class F24F 2110/40 (20180101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230251220 | Larimer |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States Department of Energy (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Joshua T. Larimer (McMurray, Pennsylvania) |
| ABSTRACT | Disclosed is an apparatus and method for crack measurement, including the steps of placing a plurality of sense leads on a surface of an object, passing a current through the object, sensing a change in electric potential in the interior of the object, and forming a crack profile of the interior of the object based on the sensed change in electric potential. |
| FILED | Tuesday, February 07, 2023 |
| APPL NO | 18/106777 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/20 (20130101) Original (OR) Class G01N 27/041 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230251236 | Meng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ying Shirley Meng (San Diego, California); Chengcheng Fang (La Jolla, California); Wurigumula Bao (La Jolla, California); Xuefeng Wang (La Jolla, California) |
| ABSTRACT | Disclosed are methods and systems for the use of titration-gas chromatography (TGC) to differentiate and quantify metallic substances (M0) and ionic metal (Mn+) in an anode material, such as in rechargeable-battery anodes of metal type (e.g., Li, Na, K, Mg, Ca, Fe, Zn, Al, etc.) or compound type (e.g., LixC6, LixSi, LixSn, etc) by using the proper titrant. |
| FILED | Thursday, February 09, 2023 |
| APPL NO | 18/167026 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/16 (20130101) G01N 31/16 (20130101) Original (OR) Class G01N 2030/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230251963 | Alwadi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mazen Alwadi (Irbid, Jordan); Vamsee Reddy Kommareddy (Leander, Texas); Clayton Hughes (Albuquerque, New Mexico); Simon David Hammond (Albuquerque, New Mexico); Amro Awad (Morrisville, North Carolina) |
| ABSTRACT | Illustrative embodiments are directed to methods, apparatus and computer program products for caching at least a fraction of data stored in a non-volatile memory in a mirror region of a dynamic random access memory. A memory controller hub of a processor chip coupled to both the non-volatile memory and the dynamic random access memory is configured to, when an update to the dynamic random access memory is cached in the mirror region of the dynamic random access memory, use the memory controller hub to write the update directly to the mirror region of the dynamic random access memory and concurrently mirror the update to the non-volatile memory to provide coherent persistent durability of the update. When a read from the dynamic random access memory is cached in the mirror region of the dynamic random access memory, embodiments can use the memory controller hub to serve the read directly from the mirror region of the dynamic random access memory to optimize read operations of persistent objects. |
| FILED | Friday, February 04, 2022 |
| APPL NO | 17/665390 |
| CURRENT CPC | Electric Digital Data Processing G06F 8/65 (20130101) G06F 12/0238 (20130101) Original (OR) Class G06F 2212/304 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230252160 | White et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Liveremore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gregory K. White (Livermore, California); Steven A. Kreek (Livermore, California) |
| ABSTRACT | A system is provided for simulating a cyberattack as a simulated cyberattack on a real industrial control facility that includes reals sensor devices. The system generates simulated sensor signals that are representative of sensor signals generated by a sensor of a real sensor device that is the target of the simulated cyberattack. The system injects the simulated sensor signals into the real sensor device so that the real sensor device generates an output based on the simulated sensor signals. The system monitors the response of a personnel of the industrial control facility. The system then generates an assessment of the response based on a target response. The system may rerun the simulated cyberattack based on the assessment. |
| FILED | Thursday, February 10, 2022 |
| APPL NO | 17/669097 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/577 (20130101) Original (OR) Class G06F 2221/034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230252373 | González-Cruz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Research Foundation of the City University of New York (New York, New York); New York University (New York, New York); Brookhaven Science Associates, LLC (Upton, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jorge E. González-Cruz (Northport, New York); Juan P. Montoya-Rincon (New York, New York); Shams Azad (New York, New York); Masoud Ghandehari (New York, New York); Michael P. Jensen (New York, New York) |
| ABSTRACT | A predictive method that uses satellite-based nighttime light (NTL) observations as a proxy for power outage data that occurred during a hurricane. The NTL data is provided to a machine learning module along with exploratory variables. The module forecasts hurricane-induced power loss based on the NTL and exploratory variables. The method does not require any data from the utility, making it useful for isolated regions or regions with limited power outage records. |
| FILED | Friday, February 03, 2023 |
| APPL NO | 18/164330 |
| CURRENT CPC | Meteorology G01W 1/00 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/04 (20130101) G06Q 10/0631 (20130101) Original (OR) Class G06Q 50/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230252663 | Quintana et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Enrico C. Quintana (Albuquerque, New Mexico); Elizabeth M. C. Jones (Cedar Crest, New Mexico); Daniel Peter Rohe (Albuquerque, New Mexico); Bryan Lee Witt (Albuquerque, New Mexico); Timothy J. Miller (Albuquerque, New Mexico); Phillip L. Reu (Albuquerque, New Mexico) |
| ABSTRACT | A method of X-ray digital image correlation is provided. The method comprises aligning cameras of an X-ray imaging system, wherein the X-ray imaging system comprises two X-ray sources pointed at a target area at a stereo angle and two corresponding X-ray detectors behind the target area. The X-ray imaging system is tuned to determine power levels of the X-ray sources that maximize image contrast and signal-to-noise ratio. The system is calibrated to determine intrinsic and extrinsic stereoscopic imaging parameters. A specimen with a random contrast pattern comprising an X-ray attenuating material is placed in the target area. Stereoscopic X-ray images are taken of the specimen and processed according to the power levels of the X-ray sources to maximize image contrast and signal-to-noise ratio and remove background objects. Kinematic quantities are determined according to changes in the contrast pattern over a number of successive images. |
| FILED | Tuesday, February 08, 2022 |
| APPL NO | 17/666723 |
| CURRENT CPC | Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor G03B 42/026 (20130101) Image Data Processing or Generation, in General G06T 7/593 (20170101) Original (OR) Class G06T 2207/10116 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230253006 | Candy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jim Candy (Danville, California); Karl A. Fisher (Brentwood, California); Christopher Roland Candy (San Ramon, California) |
| ABSTRACT | A system determines an event location of an event within an indoor environment based on an event sound generated by the event. The system employs time-reversal techniques based on a received event sound to identify the event location as being in the vicinity of one of a plurality of locator devices at locator locations in the environment. The system includes a base array located within the environment that receives an indication that an event has been detected. Upon receiving the event sound, the system generates a time-reversed event sound for each transceiver and transmits via each transceiver the time-reversed event sound for that transceiver. When a locator device receives a time-reversed event sound, the locator device determines whether the event is in the vicinity of that locator location of the locator device and, if so, outputs an indication that the event occurred at that locator location. |
| FILED | Saturday, November 05, 2022 |
| APPL NO | 17/981412 |
| CURRENT CPC | Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 21/04 (20130101) G10L 25/48 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 5/0048 (20130101) H04L 65/70 (20220501) H04L 65/75 (20220501) Wireless Communication Networks H04W 4/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230253136 | Kashikhin |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Fermi Research Alliance, LLC (Batavia, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vadim V. Kashikhin (North Aurora, Illinois) |
| ABSTRACT | A Conductor on Molded Barrel (COMB) magnet assembly optimized for High Temperature Superconducting (HTS) materials. The magnet assembly comprises a magnetic coil(s) carried by a conductor support structure and configured in cosine-theta geometry. Created using additive manufacturing, the conductor support structure features a continuous cable channel that fittedly carries and positions elongated straight portion(s) of the magnetic coil(s) parallel to a magnetic axis. The conductor support structure may be cylindrically shaped and longitudinally bored, with the continuous cable channel comprising an outer channel portion (distal on the cylinder) and an inner channel portion (proximal on the cylinder). A transition hole that joins the outer channel portion and the inner channel portion allows a single magnetic coil to be wound along both the outer and inner surfaces of the conductor support structure. The conductor support structure may be fabricated as longitudinally-symmetrical halves, and secured for operation using azimuthal and/or midplane shims. |
| FILED | Wednesday, April 19, 2023 |
| APPL NO | 18/136590 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/00 (20210101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/342 (20151001) B23K 26/354 (20151001) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/147 (20130101) H01F 5/02 (20130101) H01F 6/06 (20130101) Original (OR) Class H01F 41/048 (20130101) H01F 41/082 (20160101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230253543 | Amine et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Uchicago Argonne, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | Uchicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Khalil Amine (Oakbrook, Illinois); Tongchao Liu (Westmont, Illinois); Jun Lu (Naperville, Illinois) |
| ABSTRACT | A cathode material comprising: a cathode active material of formula LiNixMnyCozO2 or NaNixMnyCozO2 and having a partial or whole particle concentration gradient, wherein at least two or three elements concentration gradually change in the part or whole particle from the center part to the surface part of the particle (i.e. along a vector radius); 0.5≤x≤1, 0≤y≤0.33, 0≤z≤0.33. |
| FILED | Wednesday, April 12, 2023 |
| APPL NO | 18/133804 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/131 (20130101) Original (OR) Class H01M 4/364 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/1391 (20130101) H01M 10/0525 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230253563 | Su et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Chi Cheung Su (Westmont, Illinois); Jiayan Shi (Woodridge, Illinois); Rachid Amine (Bolingbrook, Illinois); Khalil Amine (Oakbrook, Illinois) |
| ABSTRACT | An electrochemical cell includes an anode that includes silicon, a conductive carbon, a lithium titanate, lithium metal, or a combination of any two or more thereof; a separator; a cathode having a cathode active material and a redox active species either mixed into the cathode or coated onto the cathode; and an electrolyte that includes a salt; and an aprotic solvent comprising a fluorinated ether solvent, a carbonate solvent, or a mixture thereof, with the proviso that the redox active species has substantially no solubility in the electrolyte. The redox active species may be a redox active organic compound or polymer. |
| FILED | Friday, February 04, 2022 |
| APPL NO | 17/592635 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/606 (20130101) Original (OR) Class H01M 10/0569 (20130101) H01M 2300/0037 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230253578 | BROWN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Versa Power Systems Ltd. c/o FuelCell Energy, Inc. (Danbury, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Casy Cloudless BROWN (Calgary, Canada); Khun Bong LUC (Calgary, Canada); Cameron James RANKIN (Calgary, Canada) |
| ABSTRACT | A top compression plate assembly for an electrochemical cell stack includes a top end plate configured to interface with a top end of a stack of electrochemical cells, a top compression plate positioned on the top end plate, and a plurality of springs coupled to a periphery of the top compression plate. The springs are configured to cause the top compression plate to exert a compressive force on the top end plate. |
| FILED | Tuesday, April 18, 2023 |
| APPL NO | 18/302709 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/026 (20130101) Original (OR) Class H01M 8/0271 (20130101) H01M 8/2432 (20160201) H01M 8/2475 (20130101) H01M 8/2485 (20130101) H01M 2008/1293 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230255115 | Ripley |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Edward Bolling Ripley (Knoxville, Tennessee) |
| ABSTRACT | Methods and systems for characterizing ultrasonic environments using piezo-electric sensor devices. In general, a piezo-electric sensor assembly is disposed and selectively repositioned in the fluid in an ultrasonic cleaning vessel, before, while, or after a component to be cleaned is present, providing quantitative and directional data regarding the high and low energy areas within the tank, where cleaning will be more or less intense, as well as areas in which standing waves without cavitation are present, representing cleaning dead spots. Further, the presence of harmonic vibrations can be detected where a fixed frequency causes a part itself to resonate. Thus, wave cancellation, reinforcement, and relative uniformity can be mapped and assessed in an ultrasonic environment, such as an ultrasonic cleaning environment or ultrasonic environment used for another purpose. |
| FILED | Tuesday, February 08, 2022 |
| APPL NO | 17/666722 |
| CURRENT CPC | Cleaning in General; Prevention of Fouling in General B08B 3/12 (20130101) B08B 13/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/042 (20130101) H01L 41/1132 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20230248414 | Sano et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Virginia Tech Intellectual Properties Inc. (Blacksburg, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael B. Sano (Cary, North Carolina); Christopher B. Arena (Blacksburg, Virginia); Scott S. Verbridge (Blacksburg, Virginia); Rafael V. Davalos (Blacksburg, Virginia) |
| ABSTRACT | The present invention relates to the field of biomedical engineering and medical treatment of diseases and disorders. Methods, devices, and systems for in vivo treatment of cell proliferative disorders are provided. In embodiments, the methods comprise the delivery of high-frequency bursts of bipolar pulses to achieve the desired modality of cell death. More specifically, embodiments of the invention relate to a device and method for destroying aberrant cells, including tumor tissues, using high-frequency, bipolar electrical pulses having a burst width on the order of microseconds and duration of single polarity on the microsecond to nanosecond scale. In embodiments, the methods rely on conventional electroporation with adjuvant drugs or irreversible electroporation to cause cell death in treated tumors. The invention can be used to treat solid tumors, such as brain tumors. |
| FILED | Monday, March 20, 2023 |
| APPL NO | 18/123719 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/14 (20130101) Original (OR) Class A61B 2018/00761 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/327 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230248651 | DESIMONE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (CHAPEL HILL, North Carolina) |
| ASSIGNEE(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (CHAPEL HILL, North Carolina) |
| INVENTOR(S) | JOSEPH M. DESIMONE (CHAPEL HILL, North Carolina); JASON P. ROLLAND (BELMONT, Massachusetts); BENJAMIN W. MAYNOR (DURHAM, North Carolina); LARKEN E. EULISS (AUGOURA HILLS, California); GINGER DENISON ROTHROCK (DURHAM, North Carolina); ANSLEY E. DENNIS (AUGUSTA, Georgia); EDWARD T. SAMULSKI (CHAPEL HILL, North Carolina); R. JUDE SAMULSKI (CHAPEL HILL, North Carolina) |
| ABSTRACT | The presently disclosed subject matter describes the use of fluorinated elastomer-based materials, in particular perfluoropolyether (PFPE)-based materials, in high-resolution soft or imprint lithographic applications, such as micro- and nanoscale replica molding, and the first nano-contact molding of organic materials to generate high fidelity features using an elastomeric mold. Accordingly, the presently disclosed subject matter describes a method for producing free-standing, isolated nanostructures of any shape using soft or imprint lithography technique. |
| FILED | Friday, April 21, 2023 |
| APPL NO | 18/305051 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) Original (OR) Class A61K 9/0097 (20130101) A61K 9/5138 (20130101) A61K 9/5153 (20130101) A61K 9/5192 (20130101) A61K 47/34 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 99/0085 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 40/00 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) Organic electric solid-state devices H10K 71/13 (20230201) Technical Subjects Covered by Former US Classification Y10T 428/3154 (20150401) Y10T 428/24273 (20150115) Y10T 428/24479 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230248832 | Chung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia); Georgia State University Research Foundation, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Leland W.K. Chung (Beverly Hills, California); Xiaojian Yang (Shannxi, China PRC); Jianjun Cheng (Champaign, Illinois); Rong Tong (Urbana, Illinois); Maged Henary (Lawrenceville, Georgia) |
| ABSTRACT | The present invention describes small molecule ligand-drug conjugates and methods of using the small molecule ligand-drug conjugates for targeted treatment of cancer in a patient in need thereof. Further described are methods of sterilizing circulating tumor cells and determining drug concentration in cancer tissue. |
| FILED | Friday, March 17, 2023 |
| APPL NO | 18/123236 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/545 (20170801) Original (OR) Class A61K 47/546 (20170801) A61K 49/0002 (20130101) A61K 49/0032 (20130101) A61K 49/0052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230249169 | Do et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | University of Houston System (Houston, Texas) |
| INVENTOR(S) | Loi Hung Do (Manvel, Texas); Zhongzheng Cai (Houston, Texas); Thi Tran (Houston, Texas); Dawei Xiao (Houston, Texas) |
| ABSTRACT | Phosphine phosphonate and phenoxyphosphine ligands bearing polyethylene glycol (PEG) chains are used as described herein to produce heterobimetallic catalysts. The ligands can be metallated selectively with palladium or nickel and secondary metal ions to provide well-defined heterobimetallic compounds. These heterobimetallic complexes exhibit accelerated reaction rates and greater thermal stability in olefin polymerization compared to other catalysts. |
| FILED | Wednesday, March 22, 2023 |
| APPL NO | 18/124708 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/2243 (20130101) Original (OR) Class B01J 31/2247 (20130101) B01J 2531/0205 (20130101) B01J 2531/0297 (20130101) B01J 2531/824 (20130101) B01J 2531/847 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 4/7014 (20130101) C08F 10/02 (20130101) C08F 2410/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20230249173 — PLATFORM FOR ROBOTIC MICRO-EXPERIMENTATION OF SOLUTION-PROCESSED MATERIALS AND DEVICES
| US 20230249173 | Amassian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aram Amassian (Raleigh, North Carolina); Tonghui Wang (Raleigh, North Carolina); Jacob Mauthe (Morrisville, North Carolina) |
| ABSTRACT | The present subject matter relates to systems and methods for the formulation of inks from stock solutions in which a liquid handler is configured to draw samples from a plurality of solution components and mix the components together to create one or more ink formulations, and a dispensing robot is configured to transfer the one or more ink formulations to a common substrate to form one or more material samples or a coating element in communication with the liquid handler is configured to transfer the one or more ink formulations to a common substrate to form one or more material samples. A controller in communication with each of the liquid handler and the dispensing robot can be configured to coordinate the creation and transfer of the one or more ink formulations. In addition, the one or more material samples can be analyzed using one or more characterization instrument configured to characterize the material samples on the common substrate. |
| FILED | Monday, February 06, 2023 |
| APPL NO | 18/106287 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 2219/00689 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/0268 (20130101) B01L 3/0293 (20130101) Original (OR) Class B01L 3/5085 (20130101) B01L 13/02 (20190801) Manipulators; Chambers Provided With Manipulation Devices B25J 9/1669 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230249368 | Padir et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Taskin Padir (Westborough, Massachusetts); Akshay Vaidya (Westford, Massachusetts); Hillel Hochsztein (Brighton, Massachusetts); Nathaniel Hanson (Boston, Massachusetts); Kristen Dorsey (Roslindale, Massachusetts); Joel B. Willick (Olivette, Missouri); Tarik Kelestemur (Boston, Massachusetts); Deniz Erdogmus (Winchester, Massachusetts) |
| ABSTRACT | Embodiments include systems for determining one or more properties of an object. In an embodiment, a system includes a gripping element, a light source, a probe element including an optical fiber, a spectrometer, and a processor. The gripping element is configured to grasp the object. The light source is configured to illuminate the object. The probe element is operatively coupled to the gripping element. The optical fiber is configured to transmit reflected light from the object. The spectrometer configured to: (i) receive the transmitted reflected light from the optical fiber and (ii) generate spectral data based on the received transmitted reflected light. The processor is configured to: (i) receive the generated spectral data from the spectrometer and (ii) determine one or more properties of the object based on the received generated spectral data. |
| FILED | Tuesday, February 07, 2023 |
| APPL NO | 18/165707 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 15/08 (20130101) B25J 19/025 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/255 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230249409 | Malhan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rishi Malhan (Los Angeles, California); Timotei Centea (Los Angeles, California); Satyandra Gupta (Los Angeles, California); Ariyan Kabir (Los Angeles, California); Brual Shah (Los Angeles, California); Aniruddha Shembekar (Los Angeles, California) |
| ABSTRACT | Methods, systems, and robots for multi-layer prepreg composite sheet layup. The robotic system may include a memory for storing a dataset including start and end point pairs of a mold of a 3D part that defines a layup sequence, a first robot or a first robot arm that is configured to conform a prepreg layer or sheet onto the mold of the 3D part, and a second robot or a second robot arm that is configured to hold or grasp the prepreg layer or sheet above the mold of the 3D part and stretch or relax the prepreg layer or sheet when the first robot or the first robot arm conforms the prepreg layer or sheet onto the mold. The robotic system may also include one or more processors connected to the first robot or the first robot arm and the second robot or the second robot arm. |
| FILED | Friday, March 31, 2023 |
| APPL NO | 18/129757 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/0087 (20130101) B25J 11/005 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/379 (20170801) Original (OR) Class B29C 64/393 (20170801) B29C 70/386 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230249441 | Singamaneni et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Srikanth Singamaneni (St. Louis, Missouri); Jingyi Luan (St. Louis, Missouri); Jeremiah Morrissey (St. Louis, Missouri); Evan Kharasch (St. Louis, Missouri) |
| ABSTRACT | Fluorescence-based techniques are the cornerstone of modern biomedical optics with applications ranging from bioimaging at various scales (organelle to organism) to detection and quantification of a wide variety of biological species of interest. However, feeble fluorescence signal remains a persistent challenge in meeting the ever-increasing demand to image, detect and quantify biological species of low abundance. Disclosed herein are simple and universal methods based on a flexible and conformal elastomeric film adsorbed with plasmonic nanostructures, referred to as “plasmonic skin” or “plasmonic patch”, that provide large and uniform enhancement of fluorescence on a variety of surfaces, through an “add-on-top” process. The novel fluorescence enhancement approach presented here represents a disease-, biomarker-, and application-agnostic ubiquitously-applicable fundamental and enabling technology to improve the sensitivity of existing analytical methodologies in an easy-to-handle and cost-effective manner, without changing and/or minimally altering the original procedures of the existing techniques. |
| FILED | Friday, May 06, 2022 |
| APPL NO | 17/662293 |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 27/06 (20130101) Original (OR) Class B32B 2307/422 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250025 | Bartel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher Bartel (Boulder, Colorado); Alan W. Weimer (Niwot, Colorado); Rebecca Jean O'Toole (Boulder, Colorado); Maila Kodas (Carlisle, Massachusetts) |
| ABSTRACT | Disclosed herein is a ceramic particle comprising a core substrate chosen from yttria-stabilized zirconia, partially stabilized zirconia, zirconium oxide, aluminum nitride, silicon nitride, silicon carbide, and cerium oxide, and a conformal coating of a sintering aid film having a thickness of less than three nanometers and covering the core substrate, and methods for producing the ceramic particle. |
| FILED | Tuesday, March 28, 2023 |
| APPL NO | 18/127498 |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/624 (20130101) C04B 35/4885 (20130101) Original (OR) Class C04B 35/62813 (20130101) C04B 2235/3217 (20130101) C04B 2235/3246 (20130101) C04B 2235/6026 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/1253 (20130101) H01M 2008/1293 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250028 | Gardiner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher Joseph Gardiner (Tampa, Florida); Justin Nussbaum (Tampa, Florida); Nathan Crane (Tampa, Florida) |
| ABSTRACT | A large area sintering platform, system, and methodology. The system includes a convection oven with a projection window disposed within a top surface of the oven. A platform is disposed within the oven below the window at a spaced distance away from the window. A powder is positioned on top of the platform, with a thermocouple positioned within the powder on the platform. A high intensity projector moves in sync with the platform, and uses low intensities and long exposure times to project an image through the window onto the powder and sinter the powder to fabricate the desired model layer by layer. |
| FILED | Thursday, March 30, 2023 |
| APPL NO | 18/193028 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/28 (20210101) B22F 10/368 (20210101) B22F 12/13 (20210101) B22F 12/44 (20210101) B22F 12/90 (20210101) Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 1/001 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/153 (20170801) B29C 64/264 (20170801) B29C 64/295 (20170801) B29C 64/393 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/00 (20141201) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/64 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250139 | Linghu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Changyang Linghu (Cambridge, Massachusetts); Edward S. Boyden (Cambridge, Massachusetts) |
| ABSTRACT | The invention, in some aspects, includes compositions encoding expression-recording islands (XRIs), compositions comprising XRIs, and methods for using XRIs for intracellular molecular recording. |
| FILED | Tuesday, October 11, 2022 |
| APPL NO | 18/045624 |
| CURRENT CPC | Peptides C07K 14/245 (20130101) Original (OR) Class C07K 2319/24 (20130101) C07K 2319/735 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250212 | Hearon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California); The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Keith Hearon (Boston, Massachusetts); Landon D. Nash (Sunnyvale, California); Thomas Wilson (San Leandro, California); Duncan J. Maitland (College Station, Texas); Mark A. Wierzbicki (College Station, Texas) |
| ABSTRACT | An embodiment includes a platform shape memory polymer system. Such an embodiment exhibits a blend of tunable, high performance mechanical attributes in combination with advanced processing capabilities and good biocompatibility. A post-polymerization crosslinking synthetic approach is employed that combines polyurethane and thiol-ene synthetic processes. Other embodiments are described herein. |
| FILED | Friday, March 24, 2023 |
| APPL NO | 18/189277 |
| CURRENT CPC | Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2105/04 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/73 (20130101) C08G 18/675 (20130101) C08G 18/758 (20130101) C08G 18/3206 (20130101) Original (OR) Class C08G 18/3212 (20130101) C08G 18/6715 (20130101) Compositions of Macromolecular Compounds C08L 75/04 (20130101) C08L 75/16 (20130101) C08L 81/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250504 | Monroe et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | James Alan Monroe (Syracuse, New York); Ibrahim (nmn) Karaman (College Station, Texas); Raymundo (nmn) Arroyave (College Station, Texas) |
| ABSTRACT | A controlled thermal coefficient product manufacturing system and method is disclosed. The disclosed product relates to the manufacture of metallic material product (MMP) having a thermal expansion coefficient (TEC) in a predetermined range. The disclosed system and method provides for a first material deformation (FMD) of the MMP that comprises at least some of a first material phase (FMP) wherein the FMP comprises martensite randomly oriented and a first thermal expansion coefficient (FTC). In response to the FMD at least some of the FMP is oriented in at least one predetermined orientation. Subsequent to deformation, the MMP comprises a second thermal expansion coefficient (STC) that is within a predetermined range and wherein the thermal expansion of the MMP is in at least one predetermined direction. The MMP may be comprised of a second material phase (SMP) that may or may not transform to the FMP in response to the FMD. |
| FILED | Tuesday, April 18, 2023 |
| APPL NO | 18/135872 |
| CURRENT CPC | Working or Processing of Sheet Metal or Metal Tubes, Rods or Profiles Without Essentially Removing Material; Punching Metal B21D 22/20 (20130101) B21D 35/002 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/14 (20130101) B23K 26/38 (20130101) B23K 26/0643 (20130101) B23K 26/0648 (20130101) B23K 26/1476 (20130101) Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 1/785 (20130101) C21D 8/005 (20130101) C21D 9/0068 (20130101) Original (OR) Class Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/08 (20130101) C22F 1/10 (20130101) C22F 1/183 (20130101) Details or Accessories of Furnaces, Kilns, Ovens, or Retorts, in so Far as They Are of Kinds Occurring in More Than One Kind of Furnace F27D 7/06 (20130101) F27D 11/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250515 | RODENE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dylan D. RODENE (Ponte Vedra, Florida); Ebtesam H. ELADGHAM (Richmond, Virginia); Indika U. ARACHCHIGE (Henrico, Virginia); Ram B. GUPTA (Glen Allen, Virginia) |
| ABSTRACT | Low-cost and earth abundant, Ni1−xMox alloy nanocrystals, with sizes ranging from 18-43 nm and varying Mo composition (0.0-11.4%), were produced by a colloidal chemistry method for alkaline HER reactions. For a water splitting current density of ˜10 mA/cm2, these alloys demonstrate over-potentials of −62 to −177 mV, which are comparable to commercial Pt-based electrocatalysts (−68 to −129 mV). The cubic Ni0.934Mo0.066 alloy nanocrystals exhibit the highest activity as alkaline HER electrocatalysts, outperforming commercial Pt/C (20 wt %) catalyst. |
| FILED | Wednesday, September 02, 2020 |
| APPL NO | 18/004706 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/054 (20220101) B22F 9/24 (20130101) B22F 2201/11 (20130101) B22F 2301/15 (20130101) B22F 2304/054 (20130101) Alloys C22C 19/03 (20130101) Original (OR) Class Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 11/089 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250714 | Alali et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Eden GeoPower, Inc. (Somerville, Massachusetts) |
| ASSIGNEE(S) | Eden GeoPower, Inc. (Somerville, Massachusetts) |
| INVENTOR(S) | Ammar Alali (Cambridge, Massachusetts); Mehrdad Mehrvand (Somerville, Massachusetts) |
| ABSTRACT | Downhole tools, systems, and methods for electric-based fracturing are disclosed. A downhole tool for electric-based fracturing may include an outer enclosure, an insulator chamber disposed at least partially within the enclosure, and an electrode disposed at least partially within the insulator chamber. The electrode may extend out from the insulator chamber and the enclosure, and may be configured to transfer electric energy to an exterior environment surrounding the downhole tool. The insulator chamber may be configured to thermally and electrically insulate at least a portion of the electrode from the exterior environment. |
| FILED | Tuesday, April 18, 2023 |
| APPL NO | 18/136169 |
| CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 17/028 (20130101) E21B 43/26 (20130101) Original (OR) Class E21B 43/2401 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230251218 | Smith |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Innogized Techologies Inc. (Chesterland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Oliver Smith (Chesterland, Ohio) |
| ABSTRACT | Systems, methods, devices, and circuitries are provided for determining a material property. In one embodiment, a method includes receiving an environmental characteristic value from a user; determining garment suitability information for the environmental characteristic value; and providing an indication of the garment suitability information to the user. |
| FILED | Monday, February 06, 2023 |
| APPL NO | 18/105964 |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 7/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/08 (20130101) G01N 21/00 (20130101) G01N 25/18 (20130101) Original (OR) Class G01N 25/22 (20130101) G01N 2015/0846 (20130101) G01N 2291/02827 (20130101) G01N 2291/02854 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230251219 | Smith |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Innogized Techologies Inc. (Chesterland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Oliver Smith (Chesterland, Ohio) |
| ABSTRACT | Systems, methods, devices, and circuitries are provided for determining a material property. In one embodiment, a measurement device includes analysis circuitry and indicia circuitry. The analysis circuitry is configured to determine a sample thermal property value of a material sample; determine an environmental characteristic value; identify a range of environmental characteristic values mapped to the sample thermal property value; determine a suitability result corresponding to a suitability of the material sample to the environmental characteristic value based on whether the environmental characteristic value falls within the identified range of environmental characteristic values. The indicia circuitry is configured to communicate the suitability result. |
| FILED | Monday, February 06, 2023 |
| APPL NO | 18/106038 |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 7/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/08 (20130101) G01N 21/00 (20130101) G01N 25/18 (20130101) Original (OR) Class G01N 25/22 (20130101) G01N 2015/0846 (20130101) G01N 2291/02827 (20130101) G01N 2291/02854 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230251577 | Yu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xiaoming Yu (Orlando, Florida); Boyang Zhou (Orlando, Florida) |
| ABSTRACT | A laser patterning method may include fabricating one or more precursor sites on a sample, generating an illumination beam including one or more pulse bursts, each pulse burst including two or more laser pulses, and scanning the illumination beam across the sample along a scan pattern including locations of the one or more precursor sites. At least one of intensities, temporal inter-pulse spacings, or spatial overlap between the two or more laser pulses in the illumination beam may be selected to selectively excite the one or more precursor sites to selectively modify the sample at the one or more precursor sites to form one or more patterned features, where a dimension of at least one feature in the one or more patterned features along at least one dimension is smaller than a size of the illumination beam on the sample. |
| FILED | Monday, February 06, 2023 |
| APPL NO | 18/106338 |
| CURRENT CPC | Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/70025 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230252372 | Singh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Shweta Singh (West Lafayette, Indiana); Carol X. Song (West Lafayette, Indiana); Venkata Sai Gargeya Vunnava (Indianapolis, Indiana) |
| ABSTRACT | System and methods for material dataflow extraction and simulation for bottom-up physical input-output table (PIOT) generation is provided. The system may receive an engineering model and an industry classification. The system may determine the type of engineering model. The system may execute the engineering model to generate the flow data. The system may build an physical supply use table (PSUT) for the region by determining, based on a flow type of data generated by the engineering model and the industry classification, a cell location in the PSUT. The system may store the data in the cell location of the PSUT. The system may generate a physical input output table (PIOT) based on PSUTs generated based for a plurality of industries. |
| FILED | Tuesday, July 06, 2021 |
| APPL NO | 18/014903 |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/08 (20130101) G06Q 10/063 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230252373 | González-Cruz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Research Foundation of the City University of New York (New York, New York); New York University (New York, New York); Brookhaven Science Associates, LLC (Upton, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jorge E. González-Cruz (Northport, New York); Juan P. Montoya-Rincon (New York, New York); Shams Azad (New York, New York); Masoud Ghandehari (New York, New York); Michael P. Jensen (New York, New York) |
| ABSTRACT | A predictive method that uses satellite-based nighttime light (NTL) observations as a proxy for power outage data that occurred during a hurricane. The NTL data is provided to a machine learning module along with exploratory variables. The module forecasts hurricane-induced power loss based on the NTL and exploratory variables. The method does not require any data from the utility, making it useful for isolated regions or regions with limited power outage records. |
| FILED | Friday, February 03, 2023 |
| APPL NO | 18/164330 |
| CURRENT CPC | Meteorology G01W 1/00 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/04 (20130101) G06Q 10/0631 (20130101) Original (OR) Class G06Q 50/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230253066 | DeGrado et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | William F. DeGrado (San Francisco, California); Nicholas Polizzi (San Francisco, California) |
| ABSTRACT | Disclosed herein, inter alia, are methods and systems for optimizing protein ligand interactions. |
| FILED | Wednesday, July 21, 2021 |
| APPL NO | 18/015582 |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 15/30 (20190201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230253198 | Venter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF WESTERN MICHICAN UNIVERSITY (Kalamazoo, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andre R. Venter (Kalamazoo, Michigan); Roshan Javanshad (Kalamazoo, Michigan) |
| ABSTRACT | A mass spectrometry device and process may include the use of helium as a nebulizing gas to provide increased signal strength in mass spectrum results. This may be implemented in, for example, ESI-based and/or DESI-based systems and/or processes. The process may be implemented utilizing a unique ionization source and, optionally, other unique components. One or more process parameters may be adjusted to provide increased signal intensity in mass spectrum results. |
| FILED | Wednesday, January 18, 2023 |
| APPL NO | 18/098471 |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/045 (20130101) H01J 49/167 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230254010 | Khodagholy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dion Khodagholy (Cresskill, New Jersey); Zifang Zhao (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dion Khodagholy (Cresskill, New Jersey); Zifang Zhao (New York, New York) |
| ABSTRACT | System for ionic communication in an electrolyte are provided, the systems including a transmitter; a first plurality of electrodes coupled to the transmitter and in contact with an electrolyte; a receiver; and a second plurality of electrodes coupled to the receiver and in contact with the electrolyte, wherein the transmitter is configured to transmit at least one signal to the receiver by manipulating ions in the electrolyte using the first plurality of electrodes. In some of these systems, the transmitter and the first plurality of electrodes are configured to be placed inside a body comprising the electrolyte. In some of these systems, the first plurality of electrodes consists of two electrodes. In some of these systems, the first plurality of electrodes includes at least three electrodes and the at least one signal is a plurality of signals. |
| FILED | Monday, February 06, 2023 |
| APPL NO | 18/106467 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0031 (20130101) Transmission H04B 5/0012 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230254206 | Yeh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Edmund Meng Yeh (Newton, Massachusetts); Khashayar Kamran (Allston, Massachusetts) |
| ABSTRACT | A framework for joint computation, caching, and request forwarding in data-centric computing-based networks comprises a virtual control plane, which operates on request counters for computations and data, and an actual plane, which handles computation requests, data requests, data objects and computation results in the physical network. A throughput optimal policy, implemented in the virtual plane, provides a basis for adaptive and distributed computation, caching, and request forwarding in the actual plane. The framework provides superior performance in terms of request satisfaction delay as compared with several baseline policies over multiple network topologies. |
| FILED | Wednesday, April 19, 2023 |
| APPL NO | 18/302959 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/547 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 41/082 (20130101) Original (OR) Class H04L 67/10 (20130101) H04L 67/568 (20220501) H04L 69/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230255121 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Weigang Wang (Tucson, Arizona); Pravin Khanal (Tucson, Arizona) |
| ABSTRACT | A magnetic memory cell can include a reference ferromagnetic layer; a barrier layer on the reference ferromagnetic layer; a multiple-interface free layer (MIFL) on the barrier layer; and a capping layer on the MIFL. The MIFL has at least three coupled sublayers, providing at least four interfaces for the MIFL. |
| FILED | Wednesday, February 09, 2022 |
| APPL NO | 17/667973 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/02 (20130101) H01L 43/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20230248039 | KOZUBAL et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Fynder Group, Inc. (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark A. KOZUBAL (Bozeman, Montana); Richard E. MACUR (Manhattan, Montana); Yuval C. AVNIEL (Missoula, Montana); Maximilian DeVane HAMILTON (Bozeman, Montana) |
| ABSTRACT | Methods of production of edible filamentous fungal biomat formulations are provided as standalone protein sources and/or protein ingredients in foodstuffs as well as a one-time use or repeated use self-contained biofilm-biomat reactor comprising a container with at least one compartment and placed within the compartment(s), a feedstock, a fungal inoculum, a gas-permeable membrane, and optionally a liquid nutrient medium. |
| FILED | Monday, March 20, 2023 |
| APPL NO | 18/123744 |
| CURRENT CPC | Dairy Products, e.g Milk, Butter, Cheese; Milk or Cheese Substitutes; Making Thereof A23C 9/1203 (20130101) Cocoa; Cocoa Products, e.g Chocolate; Substitutes for Cocoa or Cocoa Products; Confectionery; Chewing Gum; Ice-cream; Preparation Thereof A23G 9/36 (20130101) Protein Compositions for Foodstuffs; Working-up Proteins for Foodstuffs; Phosphatide Compositions for Foodstuffs A23J 3/20 (20130101) A23J 3/227 (20130101) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 29/065 (20160801) A23L 31/00 (20160801) Original (OR) Class A23L 33/195 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) A23V 2250/208 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/00 (20130101) C12M 23/24 (20130101) C12M 23/34 (20130101) C12M 23/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/14 (20130101) C12N 1/145 (20210501) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/77 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230248455 | Oca et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Siobhan Oca (Durham, North Carolina); Guangshen Ma (Durham, North Carolina); Daniel Buckland (Durham, North Carolina); Patrick Codd (Durham, North Carolina) |
| ABSTRACT | A method for performing autonomous peripheral vascular localization, including: providing a robotic system including a camera and an ultrasound probe each connected to a robotic arm; moving the robotic arm such that the camera is positioned above and/or adjacent a target surface of a body part; capturing a three-dimensional (3D) image of the target surface using the camera; generating a scanning trajectory on the target surface using the 3D image; and scanning the ultrasound probe along the scanning trajectory by moving the robotic arm to autonomously localize a target vessel in the body part. |
| FILED | Wednesday, February 08, 2023 |
| APPL NO | 18/166111 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/10 (20160201) A61B 34/32 (20160201) Original (OR) Class A61B 2034/107 (20160201) A61B 2034/2063 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230249273 | Zaffetti et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark A. Zaffetti (Suffield, Connecticut); Benjamin Abraham (Marlborough, Connecticut); Timothy Sauerhoefer (Broad Brook, Connecticut) |
| ABSTRACT | Systems and methods to control fabrication of an assembly involve a first end sheet having an interior surface and an exterior surface, opposite the interior surface. A system includes interior sheets, the interior sheets including a first interior sheet at one end of a stack of the interior sheets and including a last interior sheet at an opposite end of the stack of the two or more interior sheets, the first interior sheet being adjacent to the interior surface of the first end sheet, and a second end sheet having an interior surface and an exterior surface, opposite the interior surface. The last interior sheet is adjacent to the interior surface of the last end sheet, and the interior surface of the first end sheet or the second end sheet includes venting features, the venting features including holes or slots to channel heat, gas, or vapor during a brazing process. |
| FILED | Thursday, March 30, 2023 |
| APPL NO | 18/192777 |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 1/0012 (20130101) B23K 1/018 (20130101) Original (OR) Class B23K 2101/14 (20180801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230249417 | Bryant |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert G. Bryant (Lightfoot, Virginia) |
| ABSTRACT | Systems, methods, and devices of the various embodiments may provide Automated Tape (or Tow) Placement (ATP) systems including machine-based parts that support prepreg tape laying processes to build composite parts. Various embodiments may be applied to materials that may be consolidated during fabrication and/or may be used to fabricate parts that may require post processing steps. |
| FILED | Friday, April 14, 2023 |
| APPL NO | 18/134879 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 70/388 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230254335 | Tan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Kymie Tan (Pasadena, California); Jeremy L. Pecharich (Claremont, California); Arun A. Viswanathan (La Mirada, California); Marc I. Pomerantz (Glendale, California); Deniz E. Celik (Sunnyvale, California); Bryan Johnson (Temple City, California); Brian Wright (Goode, Virginia) |
| ABSTRACT | A method, apparatus, and system provide the ability to act on cyber risks and reduce cyber attacks. System characteristics and system information for a cyber system are gathered. The system characteristics and system information are preprocessed to identify vulnerabilities that are relevant to the cyber system. A system model of a cyber environment is generated for the cyber system. One or more features are converted from cyber threat reports to one or more semantically relevant queries over the system model. The system model is reasoned over to generate one or more answers relevant to the one or more semantically relevant queries. Attack models are executed over the system model to generate actionable intelligence and reduce cyber attacks. |
| FILED | Tuesday, August 23, 2022 |
| APPL NO | 17/821569 |
| CURRENT CPC | Electric Digital Data Processing G06F 16/2455 (20190101) Computer Systems Based on Specific Computational Models G06N 5/02 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/20 (20130101) H04L 63/1433 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20230248039 | KOZUBAL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Fynder Group, Inc. (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark A. KOZUBAL (Bozeman, Montana); Richard E. MACUR (Manhattan, Montana); Yuval C. AVNIEL (Missoula, Montana); Maximilian DeVane HAMILTON (Bozeman, Montana) |
| ABSTRACT | Methods of production of edible filamentous fungal biomat formulations are provided as standalone protein sources and/or protein ingredients in foodstuffs as well as a one-time use or repeated use self-contained biofilm-biomat reactor comprising a container with at least one compartment and placed within the compartment(s), a feedstock, a fungal inoculum, a gas-permeable membrane, and optionally a liquid nutrient medium. |
| FILED | Monday, March 20, 2023 |
| APPL NO | 18/123744 |
| CURRENT CPC | Dairy Products, e.g Milk, Butter, Cheese; Milk or Cheese Substitutes; Making Thereof A23C 9/1203 (20130101) Cocoa; Cocoa Products, e.g Chocolate; Substitutes for Cocoa or Cocoa Products; Confectionery; Chewing Gum; Ice-cream; Preparation Thereof A23G 9/36 (20130101) Protein Compositions for Foodstuffs; Working-up Proteins for Foodstuffs; Phosphatide Compositions for Foodstuffs A23J 3/20 (20130101) A23J 3/227 (20130101) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 29/065 (20160801) A23L 31/00 (20160801) Original (OR) Class A23L 33/195 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) A23V 2250/208 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/00 (20130101) C12M 23/24 (20130101) C12M 23/34 (20130101) C12M 23/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/14 (20130101) C12N 1/145 (20210501) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/77 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230248096 | WEITZ et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kennon Products, Inc. (Sheridan, Wyoming) |
| ASSIGNEE(S) | Kennon Products, Inc. (Sheridan, Wyoming) |
| INVENTOR(S) | Mark WEITZ (Sheridan, Wyoming); Justin WOOD (Sheridan, Wyoming); Zachary GREY (Sheridan, Wyoming); Brock SWECKARD (Sheridan, Wyoming); Thomas BUSHNELL (Sheridan, Wyoming); Dakotah GALI (Sheridan, Wyoming) |
| ABSTRACT | The present disclosure provides high tensile strength FCL seams, as well as methods for forming high tensile strength FCL seams by laser welding. The present disclosure also provides weldable FCL tabs for the reinforcement of both linear and curved sections of seams, as well as methods for reinforcing linear and curved sections of seams with weldable FCL tabs. |
| FILED | Wednesday, May 26, 2021 |
| APPL NO | 17/926884 |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 27/245 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250639 | Watkins |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ORB Technologies, LLC (Lexington, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Virginia Watkins (Lexington, Kentucky) |
| ABSTRACT | An apparatus for resisting a gravity load is disclosed. The apparatus has a first end member, a second end member, and a plurality of elongated structural members, each of the plurality of elongated structural members including a first end portion attached to the first end member and a second end portion attached to the second end member. The plurality of elongated structural members is oriented to resist compressive stresses or tensile stresses induced by the gravity load. The plurality of elongated structural members is formed from plants with a harvest cycle of four years or fewer. |
| FILED | Monday, April 17, 2023 |
| APPL NO | 18/301352 |
| CURRENT CPC | Structural Elements; Building Materials E04C 2/16 (20130101) Original (OR) Class E04C 2/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20230247931 | Cromer |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Walter A. Cromer (Knoxville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Walter A. Cromer (Knoxville, Tennessee) |
| ABSTRACT | Systems and methods for seed germination and planting include: a germinator unit providing an environment for seeds to germinate in water, and means to deliver the germinated seeds in batch form, suspended in an aqueous hydrogel; and a planting unit to accept batches of suspended seeds and dispense the seeds, preferably in singulated manner, to selected locations in a planting environment. The planting unit may be man-portable, mounted on a trailer or autonomous vehicle, or substantially stationary for use in a greenhouse. The planting environment may be a field or it may be a planting tray, pot, or other container for use in a greenhouse. |
| FILED | Thursday, November 17, 2022 |
| APPL NO | 17/988831 |
| CURRENT CPC | Planting; Sowing; Fertilising A01C 1/04 (20130101) Original (OR) Class A01C 7/004 (20130101) A01C 7/105 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230250639 | Watkins |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ORB Technologies, LLC (Lexington, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Virginia Watkins (Lexington, Kentucky) |
| ABSTRACT | An apparatus for resisting a gravity load is disclosed. The apparatus has a first end member, a second end member, and a plurality of elongated structural members, each of the plurality of elongated structural members including a first end portion attached to the first end member and a second end portion attached to the second end member. The plurality of elongated structural members is oriented to resist compressive stresses or tensile stresses induced by the gravity load. The plurality of elongated structural members is formed from plants with a harvest cycle of four years or fewer. |
| FILED | Monday, April 17, 2023 |
| APPL NO | 18/301352 |
| CURRENT CPC | Structural Elements; Building Materials E04C 2/16 (20130101) Original (OR) Class E04C 2/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 20230251174 | Barber et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey Barber (Vineland, New Jersey); James C. Weatherall (Linwood, New Jersey); Duane Karns (Mays Landing, New Jersey); Barry T. Smith (Egg Harbor City, New Jersey) |
| ABSTRACT | A device to determine density includes a housing, a first transducer disposed in the housing at a first position, and a second transducer disposed in the housing at a second position. The second transducer is located a distance from the first transducer. The device also includes a controller that reads a first output from the first transducer, and reads a second output from the second transducer. The controller determines a density of a liquid based on the first output, the second output, and the distance. |
| FILED | Friday, May 27, 2022 |
| APPL NO | 17/827384 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 11/00 (20130101) Original (OR) Class G01N 21/45 (20130101) G01N 27/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230251917 | CHARLSON et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David CHARLSON (Columbus, Ohio); Matthew CLINE (Grove City, Ohio); Benjamin COTE (Powell, Ohio); Joseph FLANAGAN (Abingdon, Maryland); Todd HITT (Worthington, Ohio); Jim RISSER (LUTHERVILLE TIMONIUM, Maryland); Kileen RUFF (MECHANICSBURG, Ohio); Michael WOUDSTRA (Severn, Maryland); Greg ZINK (Hllliard, Ohio) |
| ABSTRACT | In an approach to non-disruptive system enhancements and integrations, the system including: one or more computer processors; one or more computer readable storage media; and program instructions stored on the one or more computer readable storage media for execution by at least one of the one or more computer processors. The stored program instructions including instructions to: connect one or more devices to the system, wherein each device of the one or more devices is connected to the system without changing a baseline system code; assign a mode to each device; receive an event from any device of the one or more devices; determine whether each user of one or more users of the system has an appropriate privilege; and send the event to each user of the one or more users that has the appropriate privilege. |
| FILED | Thursday, February 09, 2023 |
| APPL NO | 18/166543 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/542 (20130101) Original (OR) Class G06F 9/5077 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 20230249810 | Ramakrishnan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kishore Ramakrishnan (Rexford, New York); Valeria Andreoli (Watertown, Massachusetts); Daniel L. Tweedt (West Chester, Ohio) |
| ABSTRACT | A blade for an open rotor includes a pressure side and a suction side, the pressure side and the suction side intersecting at a leading edge and a trailing edge, wherein for at least 30% of a span of the blade, the meanline of the airfoil section is shaped such that a relative curvature parameter is greater than 1.2 in a first region, less than 0.75 in a second region, and greater than 0.9 in a third region, wherein the relative curvature parameter of a region is defined by Δζn/Δζtot/Δ(x/c)n wherein ζ corresponds to the inverse tangent of the slope of a meanline curve, subscript n indicates the region, and x/c is a chordwise location normalized by the chord and wherein the first region comprises at least x/c=0.0 to 0.15 and the third region comprises at least x/c=0.80 to 1.0. |
| FILED | Wednesday, February 15, 2023 |
| APPL NO | 18/169757 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/467 (20130101) B64C 27/473 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20230248566 | RASALINGAM et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jose VENEGAS (West Roxbury, Massachusetts); United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | RAVI RASALINGAM (Boston, Massachusetts); TARSHA WARD (Lowell, Massachusetts); JOSE VENEGAS (Boston, Massachusetts); Ellen T. Roche (Cambridge, Massachusetts) |
| ABSTRACT | An oral appliance and method for treating a sleep disorder in a subject are disclosed. The appliance includes, among other elements, a palatal overlay element that engages a portion of the dorsal surface of the subject's tongue, stabilizing the tongue in a superior direction toward the hard palate. The method generally involves stabilizing the dorsal surface of a subject's tongue in a superior direction toward the subject's hard palate. |
| FILED | Thursday, June 17, 2021 |
| APPL NO | 18/010617 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 5/566 (20130101) Original (OR) Class Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/0009 (20140204) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 20230254047 | BECK et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Kristin M BECK (Livermore, California); Marko CETINA (College Park, Maryland); Michael Lurie GOLDMAN (University Park, Maryland) |
| ABSTRACT | Aspects of the present disclosure describe techniques for controlling coherent crosstalk errors that occur in multi-channel acousto-optic modulators (AOMs) by applying cancellation tones to reduce or eliminate the crosstalk errors. For example, a method and systems are described that include applying a first radio frequency (RF) tone to generate a first acoustic wave in a first channel of the multi-channel AOM, wherein a portion of the first acoustic wave interacts with a second channel to cause a crosstalk effect, and applying a second RF tone to generate a second acoustic wave in the second channel, wherein the second acoustic wave reduces or eliminates the crosstalk effect caused by the portion of the first acoustic wave. |
| FILED | Friday, November 11, 2022 |
| APPL NO | 18/054829 |
| CURRENT CPC | Transmission H04B 10/70 (20130101) Original (OR) Class H04B 10/114 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 20230250025 | Bartel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher Bartel (Boulder, Colorado); Alan W. Weimer (Niwot, Colorado); Rebecca Jean O'Toole (Boulder, Colorado); Maila Kodas (Carlisle, Massachusetts) |
| ABSTRACT | Disclosed herein is a ceramic particle comprising a core substrate chosen from yttria-stabilized zirconia, partially stabilized zirconia, zirconium oxide, aluminum nitride, silicon nitride, silicon carbide, and cerium oxide, and a conformal coating of a sintering aid film having a thickness of less than three nanometers and covering the core substrate, and methods for producing the ceramic particle. |
| FILED | Tuesday, March 28, 2023 |
| APPL NO | 18/127498 |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/624 (20130101) C04B 35/4885 (20130101) Original (OR) Class C04B 35/62813 (20130101) C04B 2235/3217 (20130101) C04B 2235/3246 (20130101) C04B 2235/6026 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/1253 (20130101) H01M 2008/1293 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 20230252398 | Jones et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anthony Cramer Jones (Brooklyn, New York); Dominik Heinrich (New York, New York); Caspar Serge Ouvaroff (New York, New York) |
| ABSTRACT | Systems, methods, interface devices, and media for the delivery of physical items using a digital stamp. Various implementations include operations such as receiving a request from a user to deliver an item to a destination using a digital stamp, wherein the item includes destination information and lacks any physical indicator that the delivery fee for the item has been paid or will be paid; receiving a destination address from the user; presenting a delivery fee for the item; and causing the generation of a digital stamp using the destination address and the delivery fee, which may be correlated with the item. |
| FILED | Wednesday, April 05, 2023 |
| APPL NO | 18/296017 |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0832 (20130101) Original (OR) Class G06Q 20/3223 (20130101) G06Q 50/32 (20130101) Ticket-issuing Apparatus; Fare-registering Apparatus; Franking Apparatus G07B 17/00508 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, August 10, 2023.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
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HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-applications-20230810.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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